Motif ID: Zic3
Z-value: 0.888

Transcription factors associated with Zic3:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Zic3 | ENSMUSG00000067860.5 | Zic3 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Zic3 | mm10_v2_chrX_+_58030999_58031018 | 0.54 | 2.5e-04 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 3.5 | GO:0055099 | response to high density lipoprotein particle(GO:0055099) |
0.5 | 2.5 | GO:0060178 | regulation of exocyst localization(GO:0060178) |
0.4 | 1.4 | GO:0033326 | cerebrospinal fluid secretion(GO:0033326) |
0.3 | 1.0 | GO:0060023 | soft palate development(GO:0060023) |
0.3 | 1.9 | GO:0002934 | desmosome organization(GO:0002934) |
0.3 | 0.9 | GO:0035621 | ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627) |
0.3 | 0.3 | GO:0048859 | formation of anatomical boundary(GO:0048859) |
0.3 | 0.3 | GO:1905072 | cardiac jelly development(GO:1905072) |
0.3 | 0.8 | GO:1904978 | regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980) |
0.3 | 0.5 | GO:1902608 | regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608) |
0.3 | 1.0 | GO:1901204 | regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204) |
0.3 | 1.8 | GO:0035754 | B cell chemotaxis(GO:0035754) |
0.2 | 0.7 | GO:0003195 | tricuspid valve formation(GO:0003195) right ventricular cardiac muscle tissue morphogenesis(GO:0003221) |
0.2 | 1.0 | GO:0035021 | negative regulation of Rac protein signal transduction(GO:0035021) |
0.2 | 2.4 | GO:1903608 | protein localization to cytoplasmic stress granule(GO:1903608) |
0.2 | 0.7 | GO:0071921 | establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) |
0.2 | 2.2 | GO:0015838 | proline transport(GO:0015824) amino-acid betaine transport(GO:0015838) |
0.2 | 1.3 | GO:0019695 | choline metabolic process(GO:0019695) |
0.2 | 0.8 | GO:1904425 | negative regulation of GTP binding(GO:1904425) |
0.2 | 0.6 | GO:0071579 | regulation of zinc ion transport(GO:0071579) |
0.2 | 1.6 | GO:0048050 | post-embryonic eye morphogenesis(GO:0048050) |
0.2 | 1.2 | GO:0042276 | error-prone translesion synthesis(GO:0042276) |
0.2 | 0.6 | GO:0014916 | regulation of lung blood pressure(GO:0014916) negative regulation of cell proliferation involved in heart morphogenesis(GO:2000137) cell proliferation involved in heart valve development(GO:2000793) |
0.2 | 0.5 | GO:0044208 | 'de novo' AMP biosynthetic process(GO:0044208) |
0.2 | 1.0 | GO:0003383 | apical constriction(GO:0003383) |
0.2 | 0.5 | GO:0097026 | dendritic cell dendrite assembly(GO:0097026) |
0.2 | 0.7 | GO:0016340 | calcium-dependent cell-matrix adhesion(GO:0016340) |
0.2 | 0.7 | GO:0015744 | succinate transport(GO:0015744) |
0.2 | 3.3 | GO:0060044 | negative regulation of cardiac muscle cell proliferation(GO:0060044) |
0.2 | 1.1 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
0.2 | 0.8 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
0.2 | 0.5 | GO:1902256 | apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256) response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) |
0.2 | 0.6 | GO:0090472 | dibasic protein processing(GO:0090472) |
0.2 | 0.3 | GO:0003273 | cell migration involved in endocardial cushion formation(GO:0003273) |
0.2 | 0.5 | GO:0060912 | cardiac cell fate specification(GO:0060912) |
0.2 | 0.6 | GO:0086046 | membrane depolarization during SA node cell action potential(GO:0086046) |
0.1 | 0.4 | GO:0060126 | somatotropin secreting cell differentiation(GO:0060126) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129) dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) renal vesicle induction(GO:0072034) regulation of testosterone biosynthetic process(GO:2000224) |
0.1 | 0.6 | GO:0046487 | glyoxylate metabolic process(GO:0046487) |
0.1 | 0.6 | GO:0046210 | nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346) |
0.1 | 0.6 | GO:1902340 | telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340) |
0.1 | 0.5 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
0.1 | 0.8 | GO:0051045 | negative regulation of membrane protein ectodomain proteolysis(GO:0051045) |
0.1 | 1.2 | GO:1900194 | negative regulation of oocyte maturation(GO:1900194) |
0.1 | 0.7 | GO:0097646 | calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647) |
0.1 | 2.7 | GO:0060579 | ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581) |
0.1 | 0.7 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
0.1 | 0.4 | GO:0007521 | muscle cell fate determination(GO:0007521) mammary placode formation(GO:0060596) |
0.1 | 0.3 | GO:0070375 | ERK5 cascade(GO:0070375) |
0.1 | 0.3 | GO:1900149 | positive regulation of Schwann cell migration(GO:1900149) |
0.1 | 0.3 | GO:0015697 | quaternary ammonium group transport(GO:0015697) |
0.1 | 0.4 | GO:0048633 | positive regulation of skeletal muscle tissue growth(GO:0048633) |
0.1 | 1.0 | GO:0010839 | negative regulation of keratinocyte proliferation(GO:0010839) |
0.1 | 0.6 | GO:1901552 | positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142) |
0.1 | 0.6 | GO:0036515 | serotonergic neuron axon guidance(GO:0036515) |
0.1 | 1.6 | GO:0008209 | androgen metabolic process(GO:0008209) |
0.1 | 0.7 | GO:2000301 | negative regulation of synaptic vesicle exocytosis(GO:2000301) |
0.1 | 0.6 | GO:0007296 | vitellogenesis(GO:0007296) |
0.1 | 0.5 | GO:0090292 | nuclear migration along microfilament(GO:0031022) nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292) |
0.1 | 0.9 | GO:0071372 | cellular response to follicle-stimulating hormone stimulus(GO:0071372) |
0.1 | 0.7 | GO:0010587 | miRNA catabolic process(GO:0010587) |
0.1 | 0.4 | GO:0051697 | protein delipidation(GO:0051697) |
0.1 | 2.1 | GO:0035024 | negative regulation of Rho protein signal transduction(GO:0035024) |
0.1 | 0.2 | GO:2001013 | epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013) |
0.1 | 0.3 | GO:0032901 | positive regulation of neurotrophin production(GO:0032901) |
0.1 | 0.5 | GO:0016266 | O-glycan processing(GO:0016266) |
0.1 | 0.8 | GO:0043568 | positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568) |
0.1 | 0.9 | GO:2000288 | positive regulation of myoblast proliferation(GO:2000288) |
0.1 | 0.4 | GO:0021914 | negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914) |
0.1 | 0.3 | GO:0021631 | optic nerve morphogenesis(GO:0021631) |
0.1 | 0.6 | GO:0071557 | histone H3-K27 demethylation(GO:0071557) |
0.1 | 0.5 | GO:0035726 | common myeloid progenitor cell proliferation(GO:0035726) |
0.1 | 0.4 | GO:0048703 | embryonic viscerocranium morphogenesis(GO:0048703) |
0.1 | 0.3 | GO:0038108 | negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108) |
0.1 | 0.6 | GO:2001197 | regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197) |
0.1 | 0.4 | GO:0098535 | de novo centriole assembly(GO:0098535) |
0.1 | 0.3 | GO:0060849 | regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849) |
0.1 | 1.0 | GO:0046069 | cGMP catabolic process(GO:0046069) |
0.1 | 1.5 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
0.1 | 0.3 | GO:1901386 | negative regulation of voltage-gated calcium channel activity(GO:1901386) |
0.1 | 0.6 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
0.1 | 0.4 | GO:1903800 | positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800) |
0.1 | 1.1 | GO:0071425 | hematopoietic stem cell proliferation(GO:0071425) |
0.1 | 0.2 | GO:0070103 | regulation of interleukin-6-mediated signaling pathway(GO:0070103) negative regulation of interleukin-6-mediated signaling pathway(GO:0070104) |
0.1 | 0.2 | GO:0010808 | positive regulation of synaptic vesicle priming(GO:0010808) |
0.1 | 0.5 | GO:0010571 | positive regulation of nuclear cell cycle DNA replication(GO:0010571) |
0.0 | 0.2 | GO:1903265 | positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265) |
0.0 | 0.5 | GO:0002347 | response to tumor cell(GO:0002347) |
0.0 | 0.2 | GO:0032914 | positive regulation of transforming growth factor beta1 production(GO:0032914) |
0.0 | 0.2 | GO:0060050 | positive regulation of protein glycosylation(GO:0060050) |
0.0 | 3.0 | GO:0045669 | positive regulation of osteoblast differentiation(GO:0045669) |
0.0 | 0.5 | GO:2000465 | regulation of glycogen (starch) synthase activity(GO:2000465) |
0.0 | 0.2 | GO:0098914 | membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914) |
0.0 | 0.3 | GO:0000707 | meiotic DNA recombinase assembly(GO:0000707) |
0.0 | 0.6 | GO:0014898 | muscle hypertrophy in response to stress(GO:0003299) cardiac muscle hypertrophy in response to stress(GO:0014898) |
0.0 | 1.0 | GO:0046856 | phosphatidylinositol dephosphorylation(GO:0046856) |
0.0 | 1.4 | GO:0097352 | autophagosome maturation(GO:0097352) |
0.0 | 0.2 | GO:0010792 | DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) |
0.0 | 0.5 | GO:2000671 | regulation of motor neuron apoptotic process(GO:2000671) |
0.0 | 0.5 | GO:1900113 | negative regulation of histone H3-K9 trimethylation(GO:1900113) |
0.0 | 0.2 | GO:0021773 | striatal medium spiny neuron differentiation(GO:0021773) |
0.0 | 0.6 | GO:0007250 | activation of NF-kappaB-inducing kinase activity(GO:0007250) |
0.0 | 0.1 | GO:0072720 | response to sorbitol(GO:0072708) response to dithiothreitol(GO:0072720) |
0.0 | 0.1 | GO:0000957 | mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960) |
0.0 | 0.3 | GO:0070986 | left/right axis specification(GO:0070986) |
0.0 | 0.4 | GO:1901620 | regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620) |
0.0 | 0.5 | GO:0070307 | lens fiber cell development(GO:0070307) |
0.0 | 0.8 | GO:0048266 | behavioral response to pain(GO:0048266) |
0.0 | 0.5 | GO:0043249 | erythrocyte maturation(GO:0043249) |
0.0 | 1.7 | GO:0030835 | negative regulation of actin filament depolymerization(GO:0030835) |
0.0 | 1.0 | GO:0060351 | cartilage development involved in endochondral bone morphogenesis(GO:0060351) |
0.0 | 0.9 | GO:0032008 | positive regulation of TOR signaling(GO:0032008) |
0.0 | 0.1 | GO:0006545 | glycine biosynthetic process(GO:0006545) |
0.0 | 0.1 | GO:1905244 | regulation of modification of synaptic structure(GO:1905244) |
0.0 | 2.3 | GO:0006635 | fatty acid beta-oxidation(GO:0006635) |
0.0 | 0.1 | GO:2001032 | regulation of double-strand break repair via nonhomologous end joining(GO:2001032) |
0.0 | 0.2 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
0.0 | 0.4 | GO:0007220 | Notch receptor processing(GO:0007220) |
0.0 | 0.6 | GO:0045956 | positive regulation of calcium ion-dependent exocytosis(GO:0045956) |
0.0 | 0.1 | GO:0001844 | protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:0001844) |
0.0 | 0.2 | GO:0000042 | protein targeting to Golgi(GO:0000042) |
0.0 | 0.2 | GO:0014067 | negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067) |
0.0 | 0.5 | GO:1901897 | regulation of relaxation of cardiac muscle(GO:1901897) |
0.0 | 0.2 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
0.0 | 0.2 | GO:0072321 | chaperone-mediated protein transport(GO:0072321) |
0.0 | 0.1 | GO:0001956 | positive regulation of neurotransmitter secretion(GO:0001956) |
0.0 | 0.3 | GO:0016926 | protein desumoylation(GO:0016926) |
0.0 | 0.4 | GO:0014046 | dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059) |
0.0 | 0.8 | GO:0034243 | regulation of transcription elongation from RNA polymerase II promoter(GO:0034243) |
0.0 | 0.7 | GO:0030517 | negative regulation of axon extension(GO:0030517) |
0.0 | 0.1 | GO:0014886 | transition between slow and fast fiber(GO:0014886) |
0.0 | 0.4 | GO:0071378 | growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378) |
0.0 | 0.1 | GO:0070212 | protein poly-ADP-ribosylation(GO:0070212) |
0.0 | 0.3 | GO:0045056 | transcytosis(GO:0045056) |
0.0 | 0.5 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
0.0 | 0.1 | GO:0001180 | transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180) |
0.0 | 3.9 | GO:0048813 | dendrite morphogenesis(GO:0048813) |
0.0 | 1.0 | GO:0036465 | synaptic vesicle recycling(GO:0036465) |
0.0 | 0.5 | GO:1900047 | negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047) |
0.0 | 1.8 | GO:0051225 | spindle assembly(GO:0051225) |
0.0 | 0.2 | GO:2001223 | negative regulation of neuron migration(GO:2001223) |
0.0 | 0.2 | GO:0035428 | hexose transmembrane transport(GO:0035428) |
0.0 | 0.1 | GO:0006362 | transcription elongation from RNA polymerase I promoter(GO:0006362) |
0.0 | 0.2 | GO:0016446 | somatic hypermutation of immunoglobulin genes(GO:0016446) |
0.0 | 0.2 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
0.0 | 0.0 | GO:0001561 | fatty acid alpha-oxidation(GO:0001561) |
0.0 | 0.8 | GO:0045670 | regulation of osteoclast differentiation(GO:0045670) |
0.0 | 0.3 | GO:1903077 | negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376) |
0.0 | 0.1 | GO:0030157 | pancreatic juice secretion(GO:0030157) |
0.0 | 0.2 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
0.0 | 0.0 | GO:0043181 | vacuolar sequestering(GO:0043181) |
0.0 | 0.1 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
0.0 | 0.1 | GO:0048148 | behavioral response to cocaine(GO:0048148) |
0.0 | 0.5 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
0.0 | 0.1 | GO:0019433 | triglyceride catabolic process(GO:0019433) |
0.0 | 0.5 | GO:1901998 | toxin transport(GO:1901998) |
0.0 | 0.7 | GO:0032088 | negative regulation of NF-kappaB transcription factor activity(GO:0032088) |
0.0 | 0.1 | GO:1902775 | mitochondrial large ribosomal subunit assembly(GO:1902775) |
0.0 | 1.4 | GO:0098656 | anion transmembrane transport(GO:0098656) |
0.0 | 0.1 | GO:0060482 | lobar bronchus development(GO:0060482) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 2.4 | GO:0097165 | nuclear stress granule(GO:0097165) |
0.2 | 1.4 | GO:0008091 | spectrin(GO:0008091) |
0.2 | 3.0 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
0.1 | 0.7 | GO:1903440 | calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440) |
0.1 | 0.7 | GO:0035189 | Rb-E2F complex(GO:0035189) |
0.1 | 0.5 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
0.1 | 1.0 | GO:0033269 | internode region of axon(GO:0033269) |
0.1 | 0.7 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
0.1 | 2.9 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
0.1 | 0.7 | GO:0016011 | dystroglycan complex(GO:0016011) |
0.1 | 1.3 | GO:0043083 | synaptic cleft(GO:0043083) |
0.1 | 0.3 | GO:1990111 | spermatoproteasome complex(GO:1990111) |
0.1 | 0.6 | GO:0012510 | trans-Golgi network transport vesicle membrane(GO:0012510) |
0.1 | 0.9 | GO:0061700 | GATOR2 complex(GO:0061700) |
0.1 | 0.4 | GO:0032983 | kainate selective glutamate receptor complex(GO:0032983) |
0.1 | 0.4 | GO:0098536 | deuterosome(GO:0098536) |
0.1 | 1.0 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
0.1 | 1.2 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
0.1 | 0.6 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
0.1 | 0.5 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
0.1 | 0.3 | GO:0033063 | Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
0.1 | 0.8 | GO:0005614 | interstitial matrix(GO:0005614) |
0.1 | 1.1 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.0 | 0.9 | GO:0097228 | sperm principal piece(GO:0097228) |
0.0 | 0.4 | GO:0070765 | gamma-secretase complex(GO:0070765) |
0.0 | 0.4 | GO:0071141 | SMAD protein complex(GO:0071141) |
0.0 | 0.3 | GO:0060091 | kinocilium(GO:0060091) |
0.0 | 0.3 | GO:0001940 | male pronucleus(GO:0001940) |
0.0 | 0.6 | GO:0045180 | basal cortex(GO:0045180) |
0.0 | 2.3 | GO:0005871 | kinesin complex(GO:0005871) |
0.0 | 0.2 | GO:0044305 | calyx of Held(GO:0044305) |
0.0 | 0.5 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
0.0 | 0.5 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
0.0 | 0.5 | GO:0031011 | Ino80 complex(GO:0031011) |
0.0 | 1.0 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
0.0 | 0.6 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
0.0 | 0.1 | GO:0070552 | BRISC complex(GO:0070552) |
0.0 | 0.2 | GO:0005744 | mitochondrial inner membrane presequence translocase complex(GO:0005744) |
0.0 | 0.2 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
0.0 | 2.4 | GO:0005905 | clathrin-coated pit(GO:0005905) |
0.0 | 0.3 | GO:0034464 | BBSome(GO:0034464) |
0.0 | 0.4 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
0.0 | 1.4 | GO:0016459 | myosin complex(GO:0016459) |
0.0 | 0.2 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
0.0 | 2.1 | GO:0032587 | ruffle membrane(GO:0032587) |
0.0 | 0.2 | GO:0000796 | condensin complex(GO:0000796) |
0.0 | 0.1 | GO:0098837 | postsynaptic recycling endosome(GO:0098837) |
0.0 | 0.4 | GO:0030137 | COPI-coated vesicle(GO:0030137) |
0.0 | 0.6 | GO:0009925 | basal plasma membrane(GO:0009925) |
0.0 | 0.6 | GO:0000788 | nuclear nucleosome(GO:0000788) |
0.0 | 1.0 | GO:0016328 | lateral plasma membrane(GO:0016328) |
0.0 | 1.1 | GO:0005811 | lipid particle(GO:0005811) |
0.0 | 0.1 | GO:0000120 | RNA polymerase I transcription factor complex(GO:0000120) |
0.0 | 0.6 | GO:0030315 | T-tubule(GO:0030315) |
0.0 | 0.2 | GO:0032420 | stereocilium(GO:0032420) |
0.0 | 0.2 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
0.0 | 0.4 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
0.0 | 0.3 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.0 | 3.0 | GO:0030226 | apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556) |
0.4 | 1.1 | GO:0036313 | phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313) |
0.3 | 1.3 | GO:0004104 | cholinesterase activity(GO:0004104) choline binding(GO:0033265) |
0.3 | 1.8 | GO:0003854 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) |
0.3 | 2.2 | GO:0015193 | L-proline transmembrane transporter activity(GO:0015193) |
0.2 | 1.2 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
0.2 | 1.4 | GO:0045545 | syndecan binding(GO:0045545) |
0.2 | 0.7 | GO:0017153 | sodium:dicarboxylate symporter activity(GO:0017153) |
0.2 | 2.5 | GO:0004300 | enoyl-CoA hydratase activity(GO:0004300) |
0.2 | 1.1 | GO:0097001 | ceramide binding(GO:0097001) |
0.2 | 0.5 | GO:0008502 | melatonin receptor activity(GO:0008502) |
0.2 | 0.8 | GO:0043812 | phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) |
0.1 | 1.0 | GO:0048101 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
0.1 | 0.7 | GO:0097643 | amylin receptor activity(GO:0097643) |
0.1 | 0.4 | GO:0004517 | nitric-oxide synthase activity(GO:0004517) |
0.1 | 0.6 | GO:0016833 | oxo-acid-lyase activity(GO:0016833) |
0.1 | 0.4 | GO:0035500 | MH2 domain binding(GO:0035500) |
0.1 | 0.6 | GO:0016708 | nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726) |
0.1 | 0.6 | GO:0008332 | low voltage-gated calcium channel activity(GO:0008332) |
0.1 | 0.4 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
0.1 | 1.0 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
0.1 | 0.7 | GO:0050265 | RNA uridylyltransferase activity(GO:0050265) |
0.1 | 0.5 | GO:0004966 | galanin receptor activity(GO:0004966) |
0.1 | 0.6 | GO:0008545 | JUN kinase kinase activity(GO:0008545) |
0.1 | 0.5 | GO:2001069 | glycogen binding(GO:2001069) |
0.1 | 0.9 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
0.1 | 1.5 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
0.1 | 0.3 | GO:0008504 | monoamine transmembrane transporter activity(GO:0008504) |
0.1 | 0.5 | GO:0086080 | protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
0.1 | 0.4 | GO:0034481 | N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537) chondroitin sulfotransferase activity(GO:0034481) |
0.1 | 0.9 | GO:0061676 | importin-alpha family protein binding(GO:0061676) |
0.1 | 0.8 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
0.1 | 0.9 | GO:0036122 | BMP binding(GO:0036122) |
0.1 | 2.1 | GO:0030506 | ankyrin binding(GO:0030506) |
0.1 | 0.6 | GO:0071558 | histone demethylase activity (H3-K27 specific)(GO:0071558) |
0.1 | 2.8 | GO:0032452 | histone demethylase activity(GO:0032452) |
0.1 | 0.4 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
0.1 | 0.9 | GO:0038191 | neuropilin binding(GO:0038191) |
0.1 | 0.7 | GO:0043237 | laminin-1 binding(GO:0043237) |
0.1 | 1.2 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
0.1 | 0.2 | GO:0001565 | phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566) |
0.1 | 1.7 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
0.1 | 1.0 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
0.1 | 0.5 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
0.1 | 0.6 | GO:0048406 | nerve growth factor binding(GO:0048406) |
0.1 | 0.3 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
0.1 | 2.0 | GO:0017091 | AU-rich element binding(GO:0017091) |
0.1 | 0.2 | GO:0097677 | STAT family protein binding(GO:0097677) |
0.1 | 1.0 | GO:0045295 | gamma-catenin binding(GO:0045295) |
0.1 | 1.5 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
0.0 | 0.4 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.0 | 0.3 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
0.0 | 0.2 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
0.0 | 0.3 | GO:0048403 | neurotrophin binding(GO:0043121) brain-derived neurotrophic factor binding(GO:0048403) |
0.0 | 0.5 | GO:0048531 | beta-1,3-galactosyltransferase activity(GO:0048531) |
0.0 | 0.5 | GO:0008301 | DNA binding, bending(GO:0008301) |
0.0 | 0.1 | GO:0008732 | threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) |
0.0 | 0.2 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
0.0 | 0.5 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
0.0 | 0.3 | GO:0000150 | recombinase activity(GO:0000150) |
0.0 | 0.3 | GO:0001849 | complement component C1q binding(GO:0001849) |
0.0 | 0.9 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
0.0 | 0.1 | GO:0050436 | microfibril binding(GO:0050436) |
0.0 | 0.5 | GO:0043495 | protein anchor(GO:0043495) |
0.0 | 1.0 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
0.0 | 0.7 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
0.0 | 0.3 | GO:0001972 | retinoic acid binding(GO:0001972) |
0.0 | 0.2 | GO:0086008 | voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008) |
0.0 | 0.1 | GO:0001165 | RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165) |
0.0 | 0.7 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
0.0 | 0.6 | GO:0070410 | co-SMAD binding(GO:0070410) |
0.0 | 2.3 | GO:0003777 | microtubule motor activity(GO:0003777) |
0.0 | 0.5 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
0.0 | 0.4 | GO:0017166 | vinculin binding(GO:0017166) |
0.0 | 0.5 | GO:0004707 | MAP kinase activity(GO:0004707) |
0.0 | 1.0 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
0.0 | 5.6 | GO:0003714 | transcription corepressor activity(GO:0003714) |
0.0 | 1.4 | GO:0003774 | motor activity(GO:0003774) |
0.0 | 0.3 | GO:0005522 | profilin binding(GO:0005522) |
0.0 | 0.6 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.0 | 0.7 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
0.0 | 0.4 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
0.0 | 0.1 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
0.0 | 0.7 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
0.0 | 0.6 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
0.0 | 1.7 | GO:0031490 | chromatin DNA binding(GO:0031490) |
0.0 | 0.3 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
0.0 | 0.3 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
0.0 | 4.5 | GO:0005096 | GTPase activator activity(GO:0005096) |
0.0 | 0.6 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
0.0 | 0.1 | GO:0003945 | N-acetyllactosamine synthase activity(GO:0003945) |
0.0 | 0.0 | GO:0004574 | oligo-1,6-glucosidase activity(GO:0004574) |
0.0 | 0.3 | GO:0042805 | actinin binding(GO:0042805) |
0.0 | 1.4 | GO:0008565 | protein transporter activity(GO:0008565) |
0.0 | 0.4 | GO:0051018 | protein kinase A binding(GO:0051018) |
0.0 | 0.1 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
0.0 | 0.2 | GO:0005355 | glucose transmembrane transporter activity(GO:0005355) |
0.0 | 0.2 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
0.0 | 0.8 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
0.0 | 0.1 | GO:0001163 | RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 0.6 | PID_ALK2_PATHWAY | ALK2 signaling events |
0.1 | 0.3 | PID_ALK1_PATHWAY | ALK1 signaling events |
0.1 | 1.4 | PID_ANTHRAX_PATHWAY | Cellular roles of Anthrax toxin |
0.1 | 0.5 | ST_PAC1_RECEPTOR_PATHWAY | PAC1 Receptor Pathway |
0.1 | 2.3 | PID_RXR_VDR_PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
0.1 | 0.7 | PID_TCR_RAS_PATHWAY | Ras signaling in the CD4+ TCR pathway |
0.0 | 1.3 | PID_SYNDECAN_2_PATHWAY | Syndecan-2-mediated signaling events |
0.0 | 2.5 | PID_PI3KCI_PATHWAY | Class I PI3K signaling events |
0.0 | 0.9 | PID_EPHA_FWDPATHWAY | EPHA forward signaling |
0.0 | 2.0 | PID_RHOA_PATHWAY | RhoA signaling pathway |
0.0 | 1.6 | PID_DELTA_NP63_PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
0.0 | 0.5 | PID_FRA_PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
0.0 | 0.3 | PID_INSULIN_GLUCOSE_PATHWAY | Insulin-mediated glucose transport |
0.0 | 0.3 | PID_EPHA2_FWD_PATHWAY | EPHA2 forward signaling |
0.0 | 1.5 | PID_ATF2_PATHWAY | ATF-2 transcription factor network |
0.0 | 1.0 | PID_EPHB_FWD_PATHWAY | EPHB forward signaling |
0.0 | 0.2 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
0.0 | 0.4 | PID_SYNDECAN_3_PATHWAY | Syndecan-3-mediated signaling events |
0.0 | 0.5 | ST_WNT_CA2_CYCLIC_GMP_PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
0.0 | 0.9 | PID_NFAT_TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
0.0 | 0.3 | ST_GA12_PATHWAY | G alpha 12 Pathway |
0.0 | 0.5 | PID_ERBB4_PATHWAY | ErbB4 signaling events |
0.0 | 0.8 | SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES | Genes related to the insulin receptor pathway |
0.0 | 0.7 | PID_CASPASE_PATHWAY | Caspase cascade in apoptosis |
0.0 | 0.6 | PID_P75_NTR_PATHWAY | p75(NTR)-mediated signaling |
0.0 | 0.6 | PID_ECADHERIN_STABILIZATION_PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
0.0 | 0.0 | PID_PDGFRA_PATHWAY | PDGFR-alpha signaling pathway |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 3.0 | REACTOME_HDL_MEDIATED_LIPID_TRANSPORT | Genes involved in HDL-mediated lipid transport |
0.2 | 1.8 | REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
0.1 | 0.5 | REACTOME_COMMON_PATHWAY | Genes involved in Common Pathway |
0.1 | 1.3 | REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
0.1 | 0.6 | REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
0.1 | 0.7 | REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
0.1 | 0.7 | REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 | Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1 |
0.1 | 0.9 | REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR | Genes involved in Regulated proteolysis of p75NTR |
0.1 | 0.7 | REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
0.1 | 1.3 | REACTOME_SYNTHESIS_OF_PC | Genes involved in Synthesis of PC |
0.1 | 0.3 | REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
0.1 | 1.2 | REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
0.1 | 1.6 | REACTOME_TIGHT_JUNCTION_INTERACTIONS | Genes involved in Tight junction interactions |
0.0 | 0.3 | REACTOME_ERKS_ARE_INACTIVATED | Genes involved in ERKs are inactivated |
0.0 | 1.8 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
0.0 | 0.7 | REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING | Genes involved in Spry regulation of FGF signaling |
0.0 | 1.4 | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
0.0 | 0.5 | REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
0.0 | 0.6 | REACTOME_ZINC_TRANSPORTERS | Genes involved in Zinc transporters |
0.0 | 0.6 | REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 | Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
0.0 | 0.4 | REACTOME_MTORC1_MEDIATED_SIGNALLING | Genes involved in mTORC1-mediated signalling |
0.0 | 0.4 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
0.0 | 0.4 | REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
0.0 | 1.1 | REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
0.0 | 0.6 | REACTOME_SIGNALING_BY_BMP | Genes involved in Signaling by BMP |
0.0 | 0.2 | REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
0.0 | 0.4 | REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
0.0 | 0.2 | REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
0.0 | 0.2 | REACTOME_REGULATION_OF_IFNG_SIGNALING | Genes involved in Regulation of IFNG signaling |
0.0 | 0.1 | REACTOME_COPI_MEDIATED_TRANSPORT | Genes involved in COPI Mediated Transport |
0.0 | 0.4 | REACTOME_INTERFERON_ALPHA_BETA_SIGNALING | Genes involved in Interferon alpha/beta signaling |
0.0 | 0.6 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
0.0 | 1.5 | REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
0.0 | 0.2 | REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |