Motif ID: Spib

Z-value: 0.808


Transcription factors associated with Spib:

Gene SymbolEntrez IDGene Name
Spib ENSMUSG00000008193.7 Spib



Activity profile for motif Spib.

activity profile for motif Spib


Sorted Z-values histogram for motif Spib

Sorted Z-values for motif Spib



Network of associatons between targets according to the STRING database.



First level regulatory network of Spib

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_23248264 4.373 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr5_+_81021202 3.979 ENSMUST00000117253.1
ENSMUST00000120128.1
Lphn3

latrophilin 3

chr17_+_93199348 3.732 ENSMUST00000064775.6
Adcyap1
adenylate cyclase activating polypeptide 1
chr10_-_6980376 2.663 ENSMUST00000105617.1
Ipcef1
interaction protein for cytohesin exchange factors 1
chrX_-_43167817 2.609 ENSMUST00000115058.1
ENSMUST00000115059.1
Tenm1

teneurin transmembrane protein 1

chr6_+_137410721 2.531 ENSMUST00000167002.1
Ptpro
protein tyrosine phosphatase, receptor type, O
chr6_-_136941694 2.465 ENSMUST00000032344.5
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr15_-_66812593 2.382 ENSMUST00000100572.3
Sla
src-like adaptor
chr5_+_149265035 2.206 ENSMUST00000130144.1
ENSMUST00000071130.3
Alox5ap

arachidonate 5-lipoxygenase activating protein

chr2_+_32721055 2.119 ENSMUST00000074248.4
Sh2d3c
SH2 domain containing 3C
chr12_-_86988676 2.101 ENSMUST00000095521.2
Zdhhc22
zinc finger, DHHC-type containing 22
chr3_-_123672321 2.077 ENSMUST00000172537.1
ENSMUST00000029602.6
Ndst3

N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3

chr2_+_121357714 2.058 ENSMUST00000125812.1
ENSMUST00000078222.2
ENSMUST00000125221.1
ENSMUST00000150271.1
Ckmt1



creatine kinase, mitochondrial 1, ubiquitous



chr6_-_136941494 1.811 ENSMUST00000111892.1
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr2_-_52558539 1.807 ENSMUST00000102760.3
ENSMUST00000102761.2
Cacnb4

calcium channel, voltage-dependent, beta 4 subunit

chr2_+_121358591 1.665 ENSMUST00000000317.6
ENSMUST00000129130.1
Ckmt1

creatine kinase, mitochondrial 1, ubiquitous

chr1_-_173333503 1.611 ENSMUST00000038227.4
Darc
Duffy blood group, chemokine receptor
chr2_+_55437100 1.611 ENSMUST00000112633.2
ENSMUST00000112632.1
Kcnj3

potassium inwardly-rectifying channel, subfamily J, member 3

chr7_+_99535439 1.563 ENSMUST00000098266.2
ENSMUST00000179755.1
Arrb1

arrestin, beta 1

chr12_-_78980758 1.458 ENSMUST00000174072.1
Tmem229b
transmembrane protein 229B
chr1_-_22315792 1.434 ENSMUST00000164877.1
Rims1
regulating synaptic membrane exocytosis 1
chr11_-_103344651 1.379 ENSMUST00000041385.7
Arhgap27
Rho GTPase activating protein 27
chr1_+_135147615 1.349 ENSMUST00000125774.1
Arl8a
ADP-ribosylation factor-like 8A
chrX_+_120290259 1.317 ENSMUST00000113358.3
ENSMUST00000050239.9
ENSMUST00000113364.3
Pcdh11x


protocadherin 11 X-linked


chr2_+_169633517 1.303 ENSMUST00000109157.1
Tshz2
teashirt zinc finger family member 2
chr4_-_43454582 1.249 ENSMUST00000107925.1
Cd72
CD72 antigen
chr4_+_44012661 1.243 ENSMUST00000107849.3
ENSMUST00000107851.3
ENSMUST00000107845.3
Clta


clathrin, light polypeptide (Lca)


chr11_-_20112876 1.240 ENSMUST00000000137.7
Actr2
ARP2 actin-related protein 2
chr18_-_35215008 1.209 ENSMUST00000091636.3
Lrrtm2
leucine rich repeat transmembrane neuronal 2
chr4_-_43454563 1.188 ENSMUST00000107926.1
Cd72
CD72 antigen
chr13_+_109903089 1.187 ENSMUST00000120664.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr7_-_126704179 1.178 ENSMUST00000106364.1
Coro1a
coronin, actin binding protein 1A
chr4_+_36952930 1.160 ENSMUST00000144029.1
Gm12371
predicted gene 12371
chr4_+_118409331 1.156 ENSMUST00000084319.4
ENSMUST00000106384.3
ENSMUST00000126089.1
ENSMUST00000073881.1
ENSMUST00000019229.8
ENSMUST00000144577.1
Med8





mediator of RNA polymerase II transcription, subunit 8 homolog (yeast)





chr11_-_115699461 1.118 ENSMUST00000106497.1
Grb2
growth factor receptor bound protein 2
chr9_+_58582240 1.117 ENSMUST00000177292.1
ENSMUST00000085651.5
Nptn

neuroplastin

chr11_-_115699307 1.102 ENSMUST00000106499.1
Grb2
growth factor receptor bound protein 2
chr14_-_124677089 1.101 ENSMUST00000095529.3
Fgf14
fibroblast growth factor 14
chr1_-_171059390 1.092 ENSMUST00000164044.1
ENSMUST00000169017.1
Fcgr3

Fc receptor, IgG, low affinity III

chr7_-_126704736 1.088 ENSMUST00000131415.1
Coro1a
coronin, actin binding protein 1A
chr4_-_136886187 1.079 ENSMUST00000046384.8
C1qb
complement component 1, q subcomponent, beta polypeptide
chr1_-_183297008 1.077 ENSMUST00000057062.5
Brox
BRO1 domain and CAAX motif containing
chr3_-_69127098 1.063 ENSMUST00000029353.2
Kpna4
karyopherin (importin) alpha 4
chr2_+_169632996 1.051 ENSMUST00000109159.2
Tshz2
teashirt zinc finger family member 2
chr13_+_5861489 1.050 ENSMUST00000000080.6
Klf6
Kruppel-like factor 6
chr12_+_28751798 1.026 ENSMUST00000035657.7
Tssc1
tumor suppressing subtransferable candidate 1
chr4_-_43454600 1.022 ENSMUST00000098105.3
ENSMUST00000098104.3
ENSMUST00000030179.4
Cd72


CD72 antigen


chr4_+_44012638 0.983 ENSMUST00000107847.3
ENSMUST00000170241.1
Clta

clathrin, light polypeptide (Lca)

chr4_-_136892867 0.982 ENSMUST00000046332.5
C1qc
complement component 1, q subcomponent, C chain
chrX_-_104413825 0.970 ENSMUST00000033695.5
Abcb7
ATP-binding cassette, sub-family B (MDR/TAP), member 7
chr2_-_91183818 0.964 ENSMUST00000075269.3
ENSMUST00000111371.1
ENSMUST00000111372.1
ENSMUST00000111381.2
ENSMUST00000077941.6
ENSMUST00000066473.5
Madd





MAP-kinase activating death domain





chr4_-_136898803 0.962 ENSMUST00000046285.5
C1qa
complement component 1, q subcomponent, alpha polypeptide
chr3_+_106721893 0.955 ENSMUST00000106736.2
ENSMUST00000154973.1
ENSMUST00000131330.1
ENSMUST00000150513.1
Lrif1



ligand dependent nuclear receptor interacting factor 1



chr8_+_3353415 0.936 ENSMUST00000098966.3
A430078G23Rik
RIKEN cDNA A430078G23 gene
chr1_-_38664947 0.931 ENSMUST00000039827.7
ENSMUST00000027250.7
Aff3

AF4/FMR2 family, member 3

chr17_+_50509518 0.920 ENSMUST00000043938.6
Plcl2
phospholipase C-like 2
chr10_+_80265035 0.909 ENSMUST00000092305.5
Dazap1
DAZ associated protein 1
chr3_-_33844255 0.905 ENSMUST00000029222.5
Ccdc39
coiled-coil domain containing 39
chr4_-_118489755 0.900 ENSMUST00000184261.1
Tie1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr3_-_101924378 0.887 ENSMUST00000106928.3
Slc22a15
solute carrier family 22 (organic anion/cation transporter), member 15
chrX_+_159708593 0.885 ENSMUST00000080394.6
Sh3kbp1
SH3-domain kinase binding protein 1
chr7_-_126704522 0.877 ENSMUST00000135087.1
Coro1a
coronin, actin binding protein 1A
chr17_+_34604262 0.869 ENSMUST00000174041.1
Agpat1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chrX_+_20848543 0.867 ENSMUST00000001155.4
ENSMUST00000122312.1
ENSMUST00000120356.1
ENSMUST00000122850.1
Araf



v-raf murine sarcoma 3611 viral oncogene homolog



chr13_+_30659999 0.842 ENSMUST00000091672.6
ENSMUST00000110310.1
ENSMUST00000095914.5
Dusp22


dual specificity phosphatase 22


chr4_-_109476666 0.822 ENSMUST00000030284.3
Rnf11
ring finger protein 11
chrX_-_107816238 0.808 ENSMUST00000120722.1
2610002M06Rik
RIKEN cDNA 2610002M06 gene
chr4_+_119195353 0.800 ENSMUST00000106345.2
Ccdc23
coiled-coil domain containing 23
chr7_-_80387935 0.785 ENSMUST00000080932.6
Fes
feline sarcoma oncogene
chr4_-_117887292 0.785 ENSMUST00000150204.1
ENSMUST00000147845.1
ENSMUST00000036380.7
ENSMUST00000136596.1
Atp6v0b



ATPase, H+ transporting, lysosomal V0 subunit B



chr3_+_106721672 0.783 ENSMUST00000098750.2
ENSMUST00000130105.1
Lrif1

ligand dependent nuclear receptor interacting factor 1

chr7_-_46919915 0.773 ENSMUST00000143413.1
ENSMUST00000014546.8
Tsg101

tumor susceptibility gene 101

chr15_-_78803015 0.771 ENSMUST00000164826.1
Card10
caspase recruitment domain family, member 10
chr10_+_86302854 0.764 ENSMUST00000132307.1
Timp3
tissue inhibitor of metalloproteinase 3
chr11_+_113657375 0.764 ENSMUST00000148736.1
ENSMUST00000142069.1
ENSMUST00000134418.1
Cog1


component of oligomeric golgi complex 1


chr18_-_6241486 0.763 ENSMUST00000025083.7
Kif5b
kinesin family member 5B
chr17_+_20945311 0.746 ENSMUST00000007708.7
Ppp2r1a
protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform
chr6_-_120822680 0.744 ENSMUST00000019354.8
Atp6v1e1
ATPase, H+ transporting, lysosomal V1 subunit E1
chr9_+_58582397 0.736 ENSMUST00000176557.1
ENSMUST00000114121.4
ENSMUST00000177064.1
Nptn


neuroplastin


chr12_-_69357120 0.723 ENSMUST00000021368.8
Nemf
nuclear export mediator factor
chr4_+_119195496 0.718 ENSMUST00000097908.3
Ccdc23
coiled-coil domain containing 23
chr5_-_138263942 0.711 ENSMUST00000048421.7
ENSMUST00000164203.1
BC037034
BC037034
cDNA sequence BC037034
cDNA sequence BC037034
chr2_+_91650116 0.709 ENSMUST00000111331.2
Arhgap1
Rho GTPase activating protein 1
chr2_+_91650169 0.697 ENSMUST00000090614.4
Arhgap1
Rho GTPase activating protein 1
chr2_+_120463566 0.691 ENSMUST00000028749.7
ENSMUST00000110721.1
Capn3

calpain 3

chr10_+_81393610 0.688 ENSMUST00000118206.1
2210404O07Rik
RIKEN cDNA 2210404O07 gene
chr4_-_117887279 0.686 ENSMUST00000132073.1
Atp6v0b
ATPase, H+ transporting, lysosomal V0 subunit B
chr16_+_21423118 0.684 ENSMUST00000096191.4
ENSMUST00000096192.5
ENSMUST00000115397.1
ENSMUST00000118923.1
ENSMUST00000122235.1
ENSMUST00000117598.1
ENSMUST00000139473.1
Vps8






vacuolar protein sorting 8 homolog (S. cerevisiae)






chr17_-_34603675 0.682 ENSMUST00000015622.7
Rnf5
ring finger protein 5
chr9_-_70503718 0.674 ENSMUST00000034739.5
Rnf111
ring finger 111
chr4_+_43641262 0.673 ENSMUST00000123351.1
ENSMUST00000128549.1
Npr2

natriuretic peptide receptor 2

chr9_-_53706211 0.655 ENSMUST00000068449.3
Rab39
RAB39, member RAS oncogene family
chr19_+_26623419 0.647 ENSMUST00000176584.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr10_-_127121125 0.645 ENSMUST00000164259.1
ENSMUST00000080975.4
Os9

amplified in osteosarcoma

chr19_+_6399857 0.642 ENSMUST00000146601.1
ENSMUST00000150713.1
Rasgrp2

RAS, guanyl releasing protein 2

chr5_-_138264013 0.631 ENSMUST00000161604.1
ENSMUST00000163268.1
BC037034
BC037034
cDNA sequence BC037034
cDNA sequence BC037034
chr7_+_87602544 0.628 ENSMUST00000167164.1
ENSMUST00000107263.2
Grm5

glutamate receptor, metabotropic 5

chr5_+_57718021 0.616 ENSMUST00000094783.3
ENSMUST00000068110.7
Pcdh7

protocadherin 7

chr5_-_134229581 0.613 ENSMUST00000111275.1
ENSMUST00000016094.6
ENSMUST00000144086.1
Ncf1


neutrophil cytosolic factor 1


chr4_+_130913120 0.612 ENSMUST00000151698.1
Laptm5
lysosomal-associated protein transmembrane 5
chr2_-_156887172 0.609 ENSMUST00000109561.3
Sla2
Src-like-adaptor 2
chr12_-_78861636 0.606 ENSMUST00000021536.7
Atp6v1d
ATPase, H+ transporting, lysosomal V1 subunit D
chr4_-_98383232 0.604 ENSMUST00000143116.1
ENSMUST00000030292.5
ENSMUST00000102793.4
Tm2d1


TM2 domain containing 1


chr1_-_130729249 0.603 ENSMUST00000171479.1
Pfkfb2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chrX_-_103981242 0.597 ENSMUST00000121153.1
ENSMUST00000070705.4
Rlim

ring finger protein, LIM domain interacting

chr2_-_156887056 0.593 ENSMUST00000029164.2
Sla2
Src-like-adaptor 2
chr4_+_119195279 0.575 ENSMUST00000030395.2
Ccdc23
coiled-coil domain containing 23
chrX_-_136741155 0.562 ENSMUST00000166930.1
ENSMUST00000113095.1
ENSMUST00000155207.1
ENSMUST00000080411.6
ENSMUST00000169418.1
Morf4l2




mortality factor 4 like 2




chr18_-_23038656 0.562 ENSMUST00000081423.6
Nol4
nucleolar protein 4
chr6_-_35539765 0.555 ENSMUST00000031866.5
Mtpn
myotrophin
chr2_+_132686931 0.550 ENSMUST00000061891.4
1110034G24Rik
RIKEN cDNA 1110034G24 gene
chr12_-_28635914 0.546 ENSMUST00000074267.3
Rps7
ribosomal protein S7
chr3_-_87263518 0.545 ENSMUST00000090986.4
Fcrls
Fc receptor-like S, scavenger receptor
chr2_+_14229390 0.530 ENSMUST00000028045.2
Mrc1
mannose receptor, C type 1
chr2_+_145934800 0.527 ENSMUST00000138774.1
ENSMUST00000152515.1
ENSMUST00000130168.1
ENSMUST00000133433.1
ENSMUST00000118002.1
4930529M08Rik




RIKEN cDNA 4930529M08 gene




chr11_+_82045705 0.516 ENSMUST00000021011.2
Ccl7
chemokine (C-C motif) ligand 7
chr19_+_4154606 0.514 ENSMUST00000061086.8
Ptprcap
protein tyrosine phosphatase, receptor type, C polypeptide-associated protein
chr13_+_44731265 0.510 ENSMUST00000173246.1
Jarid2
jumonji, AT rich interactive domain 2
chr19_-_6084873 0.501 ENSMUST00000160977.1
ENSMUST00000159859.1
Zfpl1

zinc finger like protein 1

chr19_-_11336107 0.498 ENSMUST00000056035.2
ENSMUST00000067532.4
Ms4a7

membrane-spanning 4-domains, subfamily A, member 7

chr1_+_109993982 0.497 ENSMUST00000027542.6
Cdh7
cadherin 7, type 2
chr4_-_41517326 0.496 ENSMUST00000030152.6
ENSMUST00000095126.4
1110017D15Rik

RIKEN cDNA 1110017D15 gene

chr12_-_84361802 0.492 ENSMUST00000021659.1
ENSMUST00000065536.2
Fam161b

family with sequence similarity 161, member B

chr15_-_55557748 0.453 ENSMUST00000172387.1
Mrpl13
mitochondrial ribosomal protein L13
chr9_+_94669876 0.444 ENSMUST00000033463.9
Slc9a9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chrX_+_20703906 0.444 ENSMUST00000033383.2
Usp11
ubiquitin specific peptidase 11
chr15_-_58933688 0.433 ENSMUST00000110155.1
Tatdn1
TatD DNase domain containing 1
chr1_+_153899937 0.431 ENSMUST00000086199.5
Glul
glutamate-ammonia ligase (glutamine synthetase)
chr13_+_77135513 0.424 ENSMUST00000168779.1
2210408I21Rik
RIKEN cDNA 2210408I21 gene
chr7_-_100856289 0.424 ENSMUST00000139604.1
Relt
RELT tumor necrosis factor receptor
chr5_-_24601961 0.416 ENSMUST00000030791.7
Smarcd3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr1_-_170976112 0.414 ENSMUST00000027966.7
ENSMUST00000081103.5
ENSMUST00000159688.1
Fcgr2b


Fc receptor, IgG, low affinity IIb


chr2_-_104494400 0.412 ENSMUST00000028600.7
Hipk3
homeodomain interacting protein kinase 3
chr2_-_53191214 0.411 ENSMUST00000076313.6
ENSMUST00000125243.1
Prpf40a

PRP40 pre-mRNA processing factor 40 homolog A (yeast)

chr11_-_77078404 0.410 ENSMUST00000102494.1
Ccdc55
coiled-coil domain containing 55
chr11_+_69324055 0.410 ENSMUST00000102601.3
Trappc1
trafficking protein particle complex 1
chr4_-_120815703 0.407 ENSMUST00000120779.1
Nfyc
nuclear transcription factor-Y gamma
chr19_-_6084941 0.406 ENSMUST00000025707.2
ENSMUST00000160712.1
Zfpl1

zinc finger like protein 1

chr5_-_9161692 0.398 ENSMUST00000183973.1
ENSMUST00000184372.1
ENSMUST00000095017.4
ENSMUST00000071921.6
Dmtf1



cyclin D binding myb-like transcription factor 1



chr11_+_69991633 0.395 ENSMUST00000108592.1
Gabarap
gamma-aminobutyric acid receptor associated protein
chr6_-_83121385 0.394 ENSMUST00000146328.1
ENSMUST00000113936.3
ENSMUST00000032111.4
Wbp1


WW domain binding protein 1


chr2_+_52857844 0.386 ENSMUST00000090952.4
ENSMUST00000049483.6
ENSMUST00000050719.6
Fmnl2


formin-like 2


chr19_+_6399746 0.380 ENSMUST00000113468.1
Rasgrp2
RAS, guanyl releasing protein 2
chr4_-_154160632 0.378 ENSMUST00000105639.3
ENSMUST00000030896.8
Tprgl

transformation related protein 63 regulated like

chr3_-_87263703 0.377 ENSMUST00000146512.1
Fcrls
Fc receptor-like S, scavenger receptor
chr19_+_6057925 0.377 ENSMUST00000179142.1
Fau
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)
chr2_-_6721606 0.369 ENSMUST00000150624.2
ENSMUST00000142941.1
ENSMUST00000100429.4
ENSMUST00000182879.1
Celf2



CUGBP, Elav-like family member 2



chr19_-_6084679 0.366 ENSMUST00000161548.1
Zfpl1
zinc finger like protein 1
chr3_+_32515295 0.361 ENSMUST00000029203.7
Zfp639
zinc finger protein 639
chr16_-_36666067 0.344 ENSMUST00000089620.4
Cd86
CD86 antigen
chr11_+_69324069 0.339 ENSMUST00000060956.6
ENSMUST00000108662.1
Trappc1

trafficking protein particle complex 1

chr19_+_18631927 0.336 ENSMUST00000159572.1
ENSMUST00000042392.7
Nmrk1

nicotinamide riboside kinase 1

chrX_+_7789986 0.335 ENSMUST00000136930.1
ENSMUST00000115675.2
ENSMUST00000101694.3
Gripap1


GRIP1 associated protein 1


chr12_+_33957645 0.328 ENSMUST00000049089.5
Twist1
twist basic helix-loop-helix transcription factor 1
chr4_-_124850670 0.328 ENSMUST00000163946.1
ENSMUST00000106190.3
1110065P20Rik

RIKEN cDNA 1110065P20 gene

chr19_+_6341121 0.310 ENSMUST00000025897.6
ENSMUST00000130382.1
Map4k2

mitogen-activated protein kinase kinase kinase kinase 2

chr6_-_88518760 0.308 ENSMUST00000032168.5
Sec61a1
Sec61 alpha 1 subunit (S. cerevisiae)
chr14_-_65593079 0.302 ENSMUST00000022609.5
Elp3
elongator acetyltransferase complex subunit 3
chr11_-_17008647 0.302 ENSMUST00000102881.3
Plek
pleckstrin
chr5_-_32746317 0.298 ENSMUST00000135248.1
Pisd
phosphatidylserine decarboxylase
chr19_-_18631754 0.284 ENSMUST00000025631.6
Ostf1
osteoclast stimulating factor 1
chr17_-_67950908 0.282 ENSMUST00000164647.1
Arhgap28
Rho GTPase activating protein 28
chr7_+_45896941 0.280 ENSMUST00000069772.7
ENSMUST00000107716.1
Tmem143

transmembrane protein 143

chr10_+_128058974 0.276 ENSMUST00000084771.2
Ptges3
prostaglandin E synthase 3 (cytosolic)
chr14_+_67745229 0.273 ENSMUST00000111095.2
Gnrh1
gonadotropin releasing hormone 1
chr11_+_69323963 0.269 ENSMUST00000102602.1
Trappc1
trafficking protein particle complex 1
chr14_+_80000292 0.263 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr15_+_58933774 0.258 ENSMUST00000022980.3
Ndufb9
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9
chr2_-_166155624 0.254 ENSMUST00000109249.2
Sulf2
sulfatase 2
chr1_+_87620334 0.253 ENSMUST00000042275.8
ENSMUST00000168783.1
Inpp5d

inositol polyphosphate-5-phosphatase D

chrX_-_48454152 0.253 ENSMUST00000114958.1
Elf4
E74-like factor 4 (ets domain transcription factor)
chr1_-_171294937 0.249 ENSMUST00000111302.3
ENSMUST00000080001.2
Ufc1

ubiquitin-fold modifier conjugating enzyme 1

chr17_-_46645128 0.247 ENSMUST00000003642.6
Klc4
kinesin light chain 4
chr13_+_102693522 0.241 ENSMUST00000022124.3
ENSMUST00000171267.1
ENSMUST00000167144.1
ENSMUST00000170878.1
Cd180



CD180 antigen



chr12_+_105784694 0.236 ENSMUST00000109901.2
ENSMUST00000168186.1
ENSMUST00000163473.1
ENSMUST00000170540.1
ENSMUST00000166735.1
ENSMUST00000170002.1
Papola





poly (A) polymerase alpha





chrX_-_12762069 0.227 ENSMUST00000096495.4
ENSMUST00000076016.5
Med14

mediator complex subunit 14

chr19_+_30030439 0.226 ENSMUST00000025739.7
Uhrf2
ubiquitin-like, containing PHD and RING finger domains 2
chr16_+_36934976 0.224 ENSMUST00000023531.8
Hcls1
hematopoietic cell specific Lyn substrate 1
chr9_-_66919646 0.224 ENSMUST00000041139.7
Rab8b
RAB8B, member RAS oncogene family
chr19_+_6057888 0.223 ENSMUST00000043074.5
ENSMUST00000178310.1
Fau

Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)

chr1_+_160906372 0.221 ENSMUST00000161609.1
Rc3h1
RING CCCH (C3H) domains 1
chr19_+_12846773 0.218 ENSMUST00000164001.1
Gm5244
predicted pseudogene 5244
chr4_+_109343029 0.218 ENSMUST00000030281.5
Eps15
epidermal growth factor receptor pathway substrate 15
chr8_+_108714644 0.216 ENSMUST00000043896.8
Zfhx3
zinc finger homeobox 3
chr15_-_81045467 0.215 ENSMUST00000135047.1
Mkl1
MKL (megakaryoblastic leukemia)/myocardin-like 1
chr16_-_89960815 0.214 ENSMUST00000002588.3
Tiam1
T cell lymphoma invasion and metastasis 1
chr8_+_110618577 0.213 ENSMUST00000034190.9
Vac14
Vac14 homolog (S. cerevisiae)
chr13_+_80886095 0.211 ENSMUST00000161441.1
Arrdc3
arrestin domain containing 3
chr15_-_99705490 0.206 ENSMUST00000163472.2
Gm17349
predicted gene, 17349
chr1_+_156036133 0.205 ENSMUST00000128941.1
Tor1aip2
torsin A interacting protein 2
chr4_+_49632046 0.201 ENSMUST00000156314.1
ENSMUST00000167496.1
ENSMUST00000029989.4
ENSMUST00000146547.1
Rnf20



ring finger protein 20



chr15_-_12592556 0.201 ENSMUST00000075317.5
Pdzd2
PDZ domain containing 2
chr7_-_126897424 0.200 ENSMUST00000120007.1
Tmem219
transmembrane protein 219
chr5_-_32746272 0.195 ENSMUST00000120591.1
Pisd
phosphatidylserine decarboxylase
chr4_+_130913264 0.194 ENSMUST00000156225.1
ENSMUST00000156742.1
Laptm5

lysosomal-associated protein transmembrane 5

chr3_-_59210881 0.193 ENSMUST00000040622.1
P2ry13
purinergic receptor P2Y, G-protein coupled 13
chr7_+_3290553 0.185 ENSMUST00000096744.5
Myadm
myeloid-associated differentiation marker
chr2_-_10080322 0.184 ENSMUST00000145530.1
ENSMUST00000026887.7
ENSMUST00000114896.1
ENSMUST00000114897.2
Atp5c1



ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1



chr7_-_127208423 0.182 ENSMUST00000120705.1
Tbc1d10b
TBC1 domain family, member 10b
chr8_-_41417042 0.174 ENSMUST00000033999.6
Frg1
FSHD region gene 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:0002865 negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865)
0.7 2.2 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538)
0.7 4.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.7 4.3 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.5 3.1 GO:0032796 uropod organization(GO:0032796)
0.5 2.5 GO:0003105 negative regulation of glomerular filtration(GO:0003105)
0.4 1.2 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.4 1.2 GO:0001788 antibody-dependent cellular cytotoxicity(GO:0001788)
0.4 1.9 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.4 1.4 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.3 2.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.3 1.0 GO:1904809 dense core granule localization(GO:0032253) dense core granule transport(GO:1901950) regulation of dense core granule transport(GO:1904809) positive regulation of dense core granule transport(GO:1904811)
0.3 1.0 GO:1902277 negative regulation of pancreatic amylase secretion(GO:1902277)
0.3 0.9 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.3 1.4 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.3 1.6 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.3 0.8 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.2 0.7 GO:1903538 meiotic sister chromatid cohesion, centromeric(GO:0051754) meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.2 0.7 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.2 1.6 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.2 1.1 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.2 0.6 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553) regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.2 0.6 GO:0070944 neutrophil mediated killing of bacterium(GO:0070944)
0.2 1.8 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.2 0.8 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.2 0.6 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.2 0.8 GO:0035617 stress granule disassembly(GO:0035617) plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386) regulation of voltage-gated sodium channel activity(GO:1905150)
0.2 0.9 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.1 3.0 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 0.4 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.1 0.4 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.1 0.8 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.1 0.6 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.1 0.7 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.3 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) cell proliferation involved in heart valve development(GO:2000793)
0.1 1.2 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.1 0.6 GO:0090383 phagosome acidification(GO:0090383)
0.1 0.7 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.7 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 1.4 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1 1.2 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.1 0.6 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.4 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 2.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.3 GO:0002667 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.1 0.3 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1 2.2 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.1 0.2 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 0.3 GO:0010920 negative regulation of inositol phosphate biosynthetic process(GO:0010920)
0.1 0.5 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 0.6 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 0.2 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.2 GO:1900149 positive regulation of Schwann cell migration(GO:1900149)
0.1 0.2 GO:0090327 negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.1 0.3 GO:0033087 negative regulation of immature T cell proliferation(GO:0033087)
0.1 0.3 GO:0001787 natural killer cell proliferation(GO:0001787)
0.1 0.4 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.1 0.5 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.1 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.4 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.6 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1 0.6 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 2.2 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.1 1.2 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.1 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.8 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.2 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.1 GO:0035880 embryonic nail plate morphogenesis(GO:0035880) positive regulation of catagen(GO:0051795)
0.0 0.7 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 1.3 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.2 GO:1903028 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.0 1.1 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.3 GO:0048793 pronephros development(GO:0048793)
0.0 0.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.1 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.0 0.2 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 3.7 GO:0032091 negative regulation of protein binding(GO:0032091)
0.0 0.9 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.4 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:0051461 regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.3 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.9 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 0.9 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.0 1.5 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 1.0 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.2 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.1 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.0 0.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.2 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.3 GO:0019363 pyridine nucleotide biosynthetic process(GO:0019363)
0.0 0.5 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.8 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.4 GO:0006308 DNA catabolic process(GO:0006308)
0.0 0.2 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.4 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 1.0 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.2 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
0.0 0.2 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.1 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.2 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 1.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.6 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.8 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.3 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.4 GO:0009299 mRNA transcription(GO:0009299)
0.0 0.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.2 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclase activity(GO:0031280)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0099631 postsynaptic endocytic zone cytoplasmic component(GO:0099631)
0.6 2.2 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.3 1.4 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.3 3.1 GO:0032426 stereocilium tip(GO:0032426)
0.2 1.4 GO:0097443 sorting endosome(GO:0097443)
0.2 1.5 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 1.2 GO:0030478 actin cap(GO:0030478)
0.1 0.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 1.6 GO:0031143 pseudopodium(GO:0031143)
0.1 0.8 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.6 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 0.7 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.1 3.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 0.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 1.0 GO:0030008 TRAPP complex(GO:0030008)
0.1 1.1 GO:0071564 npBAF complex(GO:0071564)
0.1 0.6 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.4 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.1 0.5 GO:0002177 manchette(GO:0002177)
0.1 0.6 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
0.1 0.8 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.9 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 0.3 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.3 GO:0033263 CORVET complex(GO:0033263)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 0.8 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.8 GO:0097386 glial cell projection(GO:0097386)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 2.2 GO:0030315 T-tubule(GO:0030315)
0.0 3.4 GO:0043204 perikaryon(GO:0043204)
0.0 2.5 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 1.0 GO:0016592 mediator complex(GO:0016592)
0.0 3.7 GO:0043195 terminal bouton(GO:0043195)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 1.8 GO:0005581 collagen trimer(GO:0005581)
0.0 3.5 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.8 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.3 GO:0042581 specific granule(GO:0042581)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.4 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.6 GO:0051233 spindle midzone(GO:0051233)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.5 GO:0071010 prespliceosome(GO:0071010)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.5 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.3 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.1 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 1.1 GO:0005643 nuclear pore(GO:0005643)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124)
0.0 0.9 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.3 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 1.3 GO:0008021 synaptic vesicle(GO:0008021)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.7 GO:0004111 creatine kinase activity(GO:0004111)
0.6 4.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.5 1.6 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.5 2.1 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.4 2.2 GO:0050544 arachidonic acid binding(GO:0050544)
0.3 1.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.3 1.6 GO:0019770 IgG receptor activity(GO:0019770)
0.3 3.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.2 3.7 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.2 2.2 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.2 2.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.2 2.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.2 2.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 0.6 GO:0001639 PLC activating G-protein coupled glutamate receptor activity(GO:0001639) A2A adenosine receptor binding(GO:0031687) G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.2 0.6 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 0.4 GO:0016880 acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.7 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.5 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 1.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.5 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.1 3.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 0.8 GO:0099609 microtubule lateral binding(GO:0099609)
0.1 0.8 GO:0046790 virion binding(GO:0046790)
0.1 0.7 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.7 GO:0031432 titin binding(GO:0031432)
0.1 0.2 GO:0071568 UFM1 transferase activity(GO:0071568)
0.1 0.3 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.1 1.3 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.3 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 0.5 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1 1.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.6 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 0.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.4 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 1.1 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.3 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 1.1 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 1.3 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 2.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.7 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.4 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 1.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 6.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.7 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 0.2 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.6 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 3.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.4 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 3.4 GO:0017124 SH3 domain binding(GO:0017124)
0.0 3.9 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.9 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 1.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.8 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 1.6 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.7 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.5 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.2 GO:0031690 adrenergic receptor binding(GO:0031690)
0.0 0.9 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.4 GO:0050699 WW domain binding(GO:0050699)
0.0 0.6 GO:0001540 beta-amyloid binding(GO:0001540)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.9 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 5.2 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.1 2.1 PID_ARF_3PATHWAY Arf1 pathway
0.1 2.1 PID_IL8_CXCR2_PATHWAY IL8- and CXCR2-mediated signaling events
0.1 2.6 PID_TCR_PATHWAY TCR signaling in naïve CD4+ T cells
0.0 3.1 PID_BCR_5PATHWAY BCR signaling pathway
0.0 1.6 ST_G_ALPHA_I_PATHWAY G alpha i Pathway
0.0 1.8 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.7 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.8 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 0.3 PID_AR_NONGENOMIC_PATHWAY Nongenotropic Androgen signaling
0.0 0.6 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 1.3 SIG_CHEMOTAXIS Genes related to chemotaxis
0.0 0.6 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.2 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.0 0.8 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 2.6 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.3 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.2 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.3 PID_TNF_PATHWAY TNF receptor signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.0 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 2.3 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 0.9 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 1.4 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 2.8 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.1 2.2 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.1 1.6 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 1.6 REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1 0.3 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 3.3 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 3.7 REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS Genes involved in Glucagon-type ligand receptors
0.1 0.8 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 0.8 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 0.6 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 2.1 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.1 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 1.0 REACTOME_KINESINS Genes involved in Kinesins
0.0 1.0 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.0 0.8 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 1.8 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.2 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 3.5 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.4 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.6 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.4 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.2 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.2 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.6 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.1 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 1.0 REACTOME_INTEGRATION_OF_ENERGY_METABOLISM Genes involved in Integration of energy metabolism
0.0 0.8 REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 0.4 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis