Motif ID: Gata2_Gata1

Z-value: 0.750

Transcription factors associated with Gata2_Gata1:

Gene SymbolEntrez IDGene Name
Gata1 ENSMUSG00000031162.8 Gata1
Gata2 ENSMUSG00000015053.8 Gata2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gata2mm10_v2_chr6_+_88198656_881986750.314.6e-02Click!
Gata1mm10_v2_chrX_-_7967817_79679100.221.7e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Gata2_Gata1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_-_116309639 6.177 ENSMUST00000036060.6
Isl1
ISL1 transcription factor, LIM/homeodomain
chr16_+_45094036 5.799 ENSMUST00000061050.5
Ccdc80
coiled-coil domain containing 80
chr16_+_45093611 5.760 ENSMUST00000099498.2
Ccdc80
coiled-coil domain containing 80
chr11_+_90030295 4.360 ENSMUST00000092788.3
Tmem100
transmembrane protein 100
chr2_+_72476159 3.886 ENSMUST00000102691.4
Cdca7
cell division cycle associated 7
chr2_+_72476225 3.421 ENSMUST00000157019.1
Cdca7
cell division cycle associated 7
chr14_-_54577578 3.418 ENSMUST00000054487.8
Ajuba
ajuba LIM protein
chr7_-_4522427 3.395 ENSMUST00000098859.3
Tnni3
troponin I, cardiac 3
chr3_-_154330543 3.171 ENSMUST00000184966.1
ENSMUST00000177846.2
Lhx8

LIM homeobox protein 8

chr2_-_36104060 3.036 ENSMUST00000112961.3
ENSMUST00000112966.3
Lhx6

LIM homeobox protein 6

chr1_-_162866502 2.994 ENSMUST00000046049.7
Fmo1
flavin containing monooxygenase 1
chr4_+_11579647 2.625 ENSMUST00000180239.1
Fsbp
fibrinogen silencer binding protein
chr1_+_172341197 2.623 ENSMUST00000056136.3
Kcnj10
potassium inwardly-rectifying channel, subfamily J, member 10
chr8_+_84701430 2.571 ENSMUST00000037165.4
Lyl1
lymphoblastomic leukemia 1
chr6_+_17306335 2.493 ENSMUST00000007799.6
ENSMUST00000115456.1
ENSMUST00000115455.2
ENSMUST00000130505.1
Cav1



caveolin 1, caveolae protein



chr7_-_139582790 2.429 ENSMUST00000106095.2
Nkx6-2
NK6 homeobox 2
chr19_-_42202150 2.394 ENSMUST00000018966.7
Sfrp5
secreted frizzled-related sequence protein 5
chr3_+_135825788 2.212 ENSMUST00000167390.1
Slc39a8
solute carrier family 39 (metal ion transporter), member 8
chr4_-_14621805 2.175 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chrX_-_107403295 2.155 ENSMUST00000033591.5
Itm2a
integral membrane protein 2A
chr18_+_57142782 2.075 ENSMUST00000139892.1
Megf10
multiple EGF-like-domains 10
chr18_-_78123324 2.046 ENSMUST00000160292.1
ENSMUST00000091813.5
Slc14a1

solute carrier family 14 (urea transporter), member 1

chr7_-_4522794 1.937 ENSMUST00000140424.1
Tnni3
troponin I, cardiac 3
chr3_-_88000350 1.892 ENSMUST00000090971.5
Bcan
brevican
chr9_-_32541589 1.810 ENSMUST00000016231.7
Fli1
Friend leukemia integration 1
chr2_+_70474923 1.783 ENSMUST00000100043.2
Sp5
trans-acting transcription factor 5
chr16_-_95459245 1.745 ENSMUST00000176345.1
ENSMUST00000121809.2
ENSMUST00000118113.1
ENSMUST00000122199.1
Erg



avian erythroblastosis virus E-26 (v-ets) oncogene related



chr5_-_125294107 1.696 ENSMUST00000127148.1
Scarb1
scavenger receptor class B, member 1
chr7_+_28833975 1.669 ENSMUST00000066723.8
Lgals4
lectin, galactose binding, soluble 4
chr7_+_110627650 1.490 ENSMUST00000033054.8
Adm
adrenomedullin
chr7_-_100662315 1.420 ENSMUST00000151123.1
ENSMUST00000107047.2
Plekhb1

pleckstrin homology domain containing, family B (evectins) member 1

chr2_-_153241402 1.319 ENSMUST00000056924.7
Plagl2
pleiomorphic adenoma gene-like 2
chr9_-_44342332 1.287 ENSMUST00000097558.3
Hmbs
hydroxymethylbilane synthase
chr5_-_121836852 1.235 ENSMUST00000086310.1
Sh2b3
SH2B adaptor protein 3
chr4_-_14621669 1.132 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr12_-_10900296 1.125 ENSMUST00000085735.2
Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chr19_+_58670358 1.113 ENSMUST00000057270.7
Pnlip
pancreatic lipase
chr11_-_102469839 1.112 ENSMUST00000103086.3
Itga2b
integrin alpha 2b
chr15_-_50890396 1.043 ENSMUST00000185183.1
Trps1
trichorhinophalangeal syndrome I (human)
chr10_-_80421847 1.021 ENSMUST00000156244.1
Tcf3
transcription factor 3
chr15_+_76904070 1.006 ENSMUST00000004072.8
Rpl8
ribosomal protein L8
chr17_-_84682932 1.002 ENSMUST00000066175.3
Abcg5
ATP-binding cassette, sub-family G (WHITE), member 5
chr4_+_41760454 0.939 ENSMUST00000108040.1
Il11ra1
interleukin 11 receptor, alpha chain 1
chr7_-_100662414 0.868 ENSMUST00000079176.6
Plekhb1
pleckstrin homology domain containing, family B (evectins) member 1
chr6_+_15185203 0.845 ENSMUST00000154448.1
Foxp2
forkhead box P2
chr6_+_17306415 0.843 ENSMUST00000150901.1
Cav1
caveolin 1, caveolae protein
chr2_+_85037212 0.812 ENSMUST00000077798.6
Ssrp1
structure specific recognition protein 1
chr19_-_7019423 0.809 ENSMUST00000040772.8
Fermt3
fermitin family homolog 3 (Drosophila)
chr10_-_13388830 0.803 ENSMUST00000079698.5
Phactr2
phosphatase and actin regulator 2
chr15_-_103251465 0.789 ENSMUST00000133600.1
ENSMUST00000134554.1
ENSMUST00000156927.1
ENSMUST00000149111.1
ENSMUST00000132836.1
Nfe2




nuclear factor, erythroid derived 2




chrX_+_73757069 0.786 ENSMUST00000002079.6
Plxnb3
plexin B3
chr3_+_79884576 0.784 ENSMUST00000145992.1
Fam198b
family with sequence similarity 198, member B
chr3_-_84479418 0.780 ENSMUST00000091002.1
Fhdc1
FH2 domain containing 1
chr4_-_14621494 0.773 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chr5_-_121836810 0.672 ENSMUST00000118580.1
ENSMUST00000040308.7
Sh2b3

SH2B adaptor protein 3

chr13_-_91388079 0.638 ENSMUST00000181054.1
A830009L08Rik
RIKEN cDNA A830009L08 gene
chr8_+_84908731 0.614 ENSMUST00000134569.1
Dnase2a
deoxyribonuclease II alpha
chr16_-_44016387 0.576 ENSMUST00000036174.3
Gramd1c
GRAM domain containing 1C
chr10_+_61648552 0.547 ENSMUST00000020286.6
Ppa1
pyrophosphatase (inorganic) 1
chr2_+_26583858 0.533 ENSMUST00000100290.5
ENSMUST00000102907.5
Egfl7

EGF-like domain 7

chr17_-_85688252 0.525 ENSMUST00000024947.7
ENSMUST00000163568.2
Six2

sine oculis-related homeobox 2

chr11_+_95337012 0.500 ENSMUST00000037502.6
Fam117a
family with sequence similarity 117, member A
chr2_-_25224653 0.496 ENSMUST00000043584.4
Tubb4b
tubulin, beta 4B class IVB
chr3_+_79884496 0.470 ENSMUST00000118853.1
Fam198b
family with sequence similarity 198, member B
chr3_+_133338936 0.463 ENSMUST00000150386.1
ENSMUST00000125858.1
Ppa2

pyrophosphatase (inorganic) 2

chr8_+_84908560 0.458 ENSMUST00000003910.6
ENSMUST00000109744.1
Dnase2a

deoxyribonuclease II alpha

chr3_-_63851251 0.436 ENSMUST00000162269.2
ENSMUST00000159676.2
ENSMUST00000175947.1
Plch1


phospholipase C, eta 1


chr1_-_14310198 0.434 ENSMUST00000168081.2
ENSMUST00000027066.6
Eya1

eyes absent 1 homolog (Drosophila)

chr10_+_53337686 0.412 ENSMUST00000046221.6
ENSMUST00000163319.1
Pln

phospholamban

chr13_+_56702983 0.410 ENSMUST00000069557.7
ENSMUST00000109876.1
Smad5

SMAD family member 5

chr7_+_110773658 0.410 ENSMUST00000143786.1
Ampd3
adenosine monophosphate deaminase 3
chr2_-_77170592 0.406 ENSMUST00000164114.2
ENSMUST00000049544.7
Ccdc141

coiled-coil domain containing 141

chr6_+_125552948 0.396 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Vwf


Von Willebrand factor homolog


chr11_+_118428493 0.394 ENSMUST00000017590.2
C1qtnf1
C1q and tumor necrosis factor related protein 1
chrX_+_150547375 0.393 ENSMUST00000066337.6
ENSMUST00000112715.1
Alas2

aminolevulinic acid synthase 2, erythroid

chr2_+_85037448 0.376 ENSMUST00000168266.1
ENSMUST00000130729.1
Ssrp1

structure specific recognition protein 1

chr7_-_44892358 0.371 ENSMUST00000003049.6
Med25
mediator of RNA polymerase II transcription, subunit 25 homolog (yeast)
chr9_-_77251829 0.365 ENSMUST00000184322.1
ENSMUST00000184316.1
Mlip

muscular LMNA-interacting protein

chr3_-_138131356 0.362 ENSMUST00000029805.8
Mttp
microsomal triglyceride transfer protein
chr15_-_98607611 0.359 ENSMUST00000096224.4
Adcy6
adenylate cyclase 6
chr10_-_115185015 0.358 ENSMUST00000006949.8
Tph2
tryptophan hydroxylase 2
chr8_+_84908680 0.353 ENSMUST00000145292.1
Dnase2a
deoxyribonuclease II alpha
chr11_-_53707269 0.353 ENSMUST00000124352.1
ENSMUST00000020649.7
Rad50

RAD50 homolog (S. cerevisiae)

chr11_-_26591729 0.346 ENSMUST00000109504.1
Vrk2
vaccinia related kinase 2
chr6_+_30541582 0.338 ENSMUST00000096066.4
Cpa2
carboxypeptidase A2, pancreatic
chr5_+_24364804 0.331 ENSMUST00000030834.4
ENSMUST00000115090.1
Nos3

nitric oxide synthase 3, endothelial cell

chr1_+_75450436 0.325 ENSMUST00000113577.1
Asic4
acid-sensing (proton-gated) ion channel family member 4
chr1_-_82586781 0.318 ENSMUST00000087050.5
Col4a4
collagen, type IV, alpha 4
chr5_+_42067960 0.317 ENSMUST00000087332.4
Gm16223
predicted gene 16223
chr18_+_7869159 0.312 ENSMUST00000170932.1
ENSMUST00000167020.1
Wac

WW domain containing adaptor with coiled-coil

chr4_-_32923455 0.310 ENSMUST00000035719.4
ENSMUST00000084749.1
Ankrd6

ankyrin repeat domain 6

chr1_+_75450699 0.305 ENSMUST00000037708.9
Asic4
acid-sensing (proton-gated) ion channel family member 4
chr3_+_106113229 0.303 ENSMUST00000079132.5
ENSMUST00000139086.1
Chia

chitinase, acidic

chr13_-_18031616 0.295 ENSMUST00000099736.2
Vdac3-ps1
voltage-dependent anion channel 3, pseudogene 1
chr10_-_83648631 0.291 ENSMUST00000146876.2
ENSMUST00000176294.1
Appl2

adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2

chr17_+_71204647 0.276 ENSMUST00000126681.1
Lpin2
lipin 2
chr11_+_118428203 0.275 ENSMUST00000124861.1
C1qtnf1
C1q and tumor necrosis factor related protein 1
chr3_+_79885930 0.274 ENSMUST00000029567.8
Fam198b
family with sequence similarity 198, member B
chrX_-_134111852 0.265 ENSMUST00000033610.6
Nox1
NADPH oxidase 1
chr9_+_109832998 0.265 ENSMUST00000119376.1
ENSMUST00000122343.1
Nme6

NME/NM23 nucleoside diphosphate kinase 6

chr14_-_64455903 0.231 ENSMUST00000067927.7
Msra
methionine sulfoxide reductase A
chr3_+_135826075 0.229 ENSMUST00000029810.5
Slc39a8
solute carrier family 39 (metal ion transporter), member 8
chr17_+_46650328 0.228 ENSMUST00000043464.7
Cul7
cullin 7
chrX_+_10485121 0.222 ENSMUST00000076354.6
ENSMUST00000115526.1
Tspan7

tetraspanin 7

chr14_-_55560340 0.217 ENSMUST00000066106.3
A730061H03Rik
RIKEN cDNA A730061H03 gene
chr1_+_75507077 0.216 ENSMUST00000037330.4
Inha
inhibin alpha
chr10_+_90576252 0.213 ENSMUST00000182427.1
ENSMUST00000182053.1
ENSMUST00000182113.1
Anks1b


ankyrin repeat and sterile alpha motif domain containing 1B


chrX_-_18461371 0.207 ENSMUST00000044188.4
4930578C19Rik
RIKEN cDNA 4930578C19 gene
chr10_-_14718191 0.207 ENSMUST00000020016.4
Gje1
gap junction protein, epsilon 1
chr8_+_84901928 0.187 ENSMUST00000067060.7
Klf1
Kruppel-like factor 1 (erythroid)
chr10_+_5593718 0.184 ENSMUST00000051809.8
Myct1
myc target 1
chr4_-_46404224 0.182 ENSMUST00000107764.2
Hemgn
hemogen
chr3_-_146839365 0.181 ENSMUST00000084614.3
Gm10288
predicted gene 10288
chr19_+_24875679 0.179 ENSMUST00000073080.5
Gm10053
predicted gene 10053
chr3_-_94886945 0.177 ENSMUST00000005923.6
Psmb4
proteasome (prosome, macropain) subunit, beta type 4
chr8_+_13037308 0.176 ENSMUST00000063820.5
ENSMUST00000033821.4
F10

coagulation factor X

chr17_-_45593626 0.171 ENSMUST00000163905.1
ENSMUST00000167692.1
Slc29a1

solute carrier family 29 (nucleoside transporters), member 1

chr2_+_69670100 0.164 ENSMUST00000100050.3
Klhl41
kelch-like 41
chr9_-_77251871 0.163 ENSMUST00000183955.1
Mlip
muscular LMNA-interacting protein
chr10_+_90576708 0.155 ENSMUST00000182430.1
ENSMUST00000182960.1
ENSMUST00000182045.1
ENSMUST00000182083.1
Anks1b



ankyrin repeat and sterile alpha motif domain containing 1B



chr2_-_121037048 0.144 ENSMUST00000102490.3
Epb4.2
erythrocyte protein band 4.2
chr1_+_165788681 0.142 ENSMUST00000161971.1
ENSMUST00000178336.1
ENSMUST00000005907.5
ENSMUST00000027849.4
Cd247



CD247 antigen



chr10_+_90576570 0.142 ENSMUST00000182786.1
ENSMUST00000182600.1
Anks1b

ankyrin repeat and sterile alpha motif domain containing 1B

chr8_+_46490968 0.133 ENSMUST00000110372.1
ENSMUST00000130563.1
Acsl1

acyl-CoA synthetase long-chain family member 1

chr10_+_90576678 0.121 ENSMUST00000182284.1
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr13_+_38345716 0.108 ENSMUST00000171970.1
Bmp6
bone morphogenetic protein 6
chrX_+_99975570 0.094 ENSMUST00000113779.1
ENSMUST00000113776.1
ENSMUST00000113775.1
ENSMUST00000113780.1
ENSMUST00000113778.1
ENSMUST00000113781.1
ENSMUST00000113783.1
ENSMUST00000071453.2
ENSMUST00000113777.1
Eda








ectodysplasin-A








chr17_+_36869567 0.091 ENSMUST00000060524.9
Trim10
tripartite motif-containing 10
chr4_+_124802543 0.083 ENSMUST00000138807.1
ENSMUST00000030723.2
ENSMUST00000175875.1
Mtf1


metal response element binding transcription factor 1


chr4_-_59438633 0.071 ENSMUST00000040166.7
ENSMUST00000107544.1
Susd1

sushi domain containing 1

chr11_+_70639118 0.066 ENSMUST00000055184.6
ENSMUST00000108551.2
Gp1ba

glycoprotein 1b, alpha polypeptide

chr3_-_59262825 0.063 ENSMUST00000050360.7
P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr8_+_4325205 0.057 ENSMUST00000127460.1
ENSMUST00000136191.1
ENSMUST00000069762.9
ENSMUST00000098949.4
Ccl25

Ccl25

chemokine (C-C motif) ligand 25

chemokine (C-C motif) ligand 25

chr7_-_99238564 0.054 ENSMUST00000064231.7
Mogat2
monoacylglycerol O-acyltransferase 2
chr1_+_165788746 0.050 ENSMUST00000161559.2
Cd247
CD247 antigen
chr18_-_43477764 0.050 ENSMUST00000057110.9
Eif3j2
eukaryotic translation initiation factor 3, subunit J2
chr16_-_64786321 0.048 ENSMUST00000052588.4
Zfp654
zinc finger protein 654
chr6_-_122856151 0.045 ENSMUST00000042081.8
C3ar1
complement component 3a receptor 1
chr9_-_21963568 0.040 ENSMUST00000006397.5
Epor
erythropoietin receptor
chr1_+_135818593 0.034 ENSMUST00000038760.8
Lad1
ladinin
chr9_+_44069421 0.034 ENSMUST00000114830.2
Usp2
ubiquitin specific peptidase 2
chr10_+_90576777 0.015 ENSMUST00000183136.1
ENSMUST00000182595.1
Anks1b

ankyrin repeat and sterile alpha motif domain containing 1B

chr14_+_66784523 0.014 ENSMUST00000071522.2
Gm10032
predicted gene 10032
chr4_+_43493345 0.013 ENSMUST00000030181.5
ENSMUST00000107922.2
Ccdc107

coiled-coil domain containing 107

chr6_+_15185456 0.012 ENSMUST00000115472.1
ENSMUST00000115474.1
ENSMUST00000031545.7
ENSMUST00000137628.1
Foxp2



forkhead box P2



chr3_-_94473591 0.011 ENSMUST00000029785.3
Riiad1
regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1
chr15_+_80623499 0.010 ENSMUST00000043149.7
Grap2
GRB2-related adaptor protein 2
chr8_+_105636509 0.007 ENSMUST00000005841.9
Ctcf
CCCTC-binding factor

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.2 GO:0032650 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) cardiac cell fate determination(GO:0060913)
0.9 5.3 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.8 2.4 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.7 2.0 GO:0071918 urea transmembrane transport(GO:0071918)
0.7 3.3 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.7 2.6 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.6 3.8 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.6 4.1 GO:0019532 oxalate transport(GO:0019532)
0.6 1.7 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.5 4.4 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.5 3.0 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.5 3.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.4 2.6 GO:0001955 blood vessel maturation(GO:0001955)
0.4 2.2 GO:0002317 plasma cell differentiation(GO:0002317) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.3 2.4 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.3 1.0 GO:0030300 regulation of intestinal cholesterol absorption(GO:0030300) negative regulation of intestinal absorption(GO:1904479)
0.2 3.0 GO:0070995 toxin metabolic process(GO:0009404) NADPH oxidation(GO:0070995)
0.2 1.5 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.2 2.4 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.2 1.1 GO:0030299 intestinal cholesterol absorption(GO:0030299)
0.2 0.4 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.2 1.0 GO:0002326 B cell lineage commitment(GO:0002326)
0.2 0.8 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.1 0.8 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.1 0.5 GO:0097168 condensed mesenchymal cell proliferation(GO:0072137) mesenchymal stem cell proliferation(GO:0097168)
0.1 0.4 GO:0035811 negative regulation of urine volume(GO:0035811)
0.1 0.3 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.1 0.3 GO:0003057 regulation of the force of heart contraction by chemical signal(GO:0003057)
0.1 1.3 GO:0018065 protein-cofactor linkage(GO:0018065)
0.1 1.4 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.1 0.8 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 1.8 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.1 0.3 GO:0072592 oxygen metabolic process(GO:0072592)
0.1 1.3 GO:0034377 plasma lipoprotein particle assembly(GO:0034377)
0.1 10.8 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 0.8 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.1 1.8 GO:0035855 megakaryocyte development(GO:0035855)
0.1 0.4 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.9 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 0.4 GO:0000019 regulation of mitotic recombination(GO:0000019) telomeric 3' overhang formation(GO:0031860)
0.1 0.3 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.1 1.0 GO:0046697 decidualization(GO:0046697)
0.1 0.4 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.1 0.2 GO:0001880 Mullerian duct regression(GO:0001880)
0.1 0.4 GO:0006586 tryptophan metabolic process(GO:0006568) indolalkylamine metabolic process(GO:0006586)
0.0 0.4 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 1.0 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.4 GO:0086023 adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.0 3.1 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 0.5 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.3 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.2 GO:0046880 regulation of gonadotropin secretion(GO:0032276) regulation of follicle-stimulating hormone secretion(GO:0046880) follicle-stimulating hormone secretion(GO:0046884)
0.0 0.1 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 1.0 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.3 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.4 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.2 GO:0015862 uridine transport(GO:0015862)
0.0 0.3 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 1.2 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.2 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 1.5 GO:0021766 hippocampus development(GO:0021766)
0.0 0.1 GO:0044539 long-chain fatty acid import(GO:0044539)
0.0 0.1 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.0 0.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.0 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.5 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 0.2 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.0 0.3 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.4 GO:0030168 platelet activation(GO:0030168)
0.0 0.4 GO:0021799 cerebral cortex radially oriented cell migration(GO:0021799) centrosome localization(GO:0051642)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.3 GO:1990584 cardiac Troponin complex(GO:1990584)
0.7 10.6 GO:0005614 interstitial matrix(GO:0005614)
0.5 3.2 GO:0001674 female germ cell nucleus(GO:0001674)
0.3 3.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.2 2.4 GO:0097449 astrocyte projection(GO:0097449)
0.1 2.4 GO:0031528 microvillus membrane(GO:0031528)
0.1 1.0 GO:0098533 ATPase dependent transmembrane transport complex(GO:0098533)
0.1 2.1 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.2 GO:0043512 inhibin-betaglycan-ActRII complex(GO:0034673) inhibin A complex(GO:0043512)
0.1 0.3 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.3 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1 1.1 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.1 0.4 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.5 GO:0045298 tubulin complex(GO:0045298)
0.0 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.2 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 4.4 GO:0043204 perikaryon(GO:0043204)
0.0 1.0 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 3.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)
0.0 2.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.2 GO:0005839 proteasome core complex(GO:0005839)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.3 GO:0030172 troponin C binding(GO:0030172)
1.1 1.1 GO:0070051 fibrinogen binding(GO:0070051)
0.9 2.6 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.7 3.3 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.6 3.0 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.6 1.7 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.5 1.4 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.4 11.6 GO:0001968 fibronectin binding(GO:0001968)
0.4 2.0 GO:0015265 urea channel activity(GO:0015265)
0.4 4.1 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.3 2.1 GO:0001849 complement component C1q binding(GO:0001849)
0.3 1.7 GO:0016936 galactoside binding(GO:0016936)
0.3 3.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.3 1.0 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.2 0.9 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.2 1.3 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.2 6.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 1.0 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 0.4 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 0.4 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.1 1.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.3 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 2.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.1 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 2.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.3 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 0.8 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1 0.2 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 0.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.4 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 0.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.4 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.1 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.0 0.4 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 2.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 1.7 GO:0005179 hormone activity(GO:0005179)
0.0 1.9 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.8 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.6 GO:0005272 sodium channel activity(GO:0005272)
0.0 1.8 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.4 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.1 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.2 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.5 GO:0005112 Notch binding(GO:0005112)
0.0 0.0 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.1 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.4 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 1.0 GO:0019843 rRNA binding(GO:0019843)
0.0 13.3 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 0.7 GO:0005518 collagen binding(GO:0005518)
0.0 0.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0070700 BMP receptor binding(GO:0070700)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.3 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.1 7.0 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.1 1.1 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.1 1.8 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.0 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.2 PID_EPO_PATHWAY EPO signaling pathway
0.0 0.2 PID_ALK2_PATHWAY ALK2 signaling events
0.0 5.1 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 0.4 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 1.2 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.8 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.2 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.0 2.2 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.4 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.3 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.2 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.2 4.3 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.2 7.5 REACTOME_LIPID_DIGESTION_MOBILIZATION_AND_TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
0.1 2.4 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.1 1.9 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.1 3.0 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 1.5 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 2.0 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 0.2 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 2.6 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 1.4 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.2 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.1 0.2 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.0 1.2 REACTOME_ELONGATION_ARREST_AND_RECOVERY Genes involved in Elongation arrest and recovery
0.0 3.8 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.4 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.4 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.0 0.1 REACTOME_ADP_SIGNALLING_THROUGH_P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.5 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.2 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.0 0.8 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.4 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.4 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 1.0 REACTOME_TRNA_AMINOACYLATION Genes involved in tRNA Aminoacylation
0.0 1.5 REACTOME_G_ALPHA_S_SIGNALLING_EVENTS Genes involved in G alpha (s) signalling events
0.0 0.3 REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.4 REACTOME_MYOGENESIS Genes involved in Myogenesis