Motif ID: Nr1h4

Z-value: 0.656


Transcription factors associated with Nr1h4:

Gene SymbolEntrez IDGene Name
Nr1h4 ENSMUSG00000047638.9 Nr1h4



Activity profile for motif Nr1h4.

activity profile for motif Nr1h4


Sorted Z-values histogram for motif Nr1h4

Sorted Z-values for motif Nr1h4



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr1h4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_+_50752758 3.906 ENSMUST00000034562.7
Cryab
crystallin, alpha B
chr4_+_53440388 2.570 ENSMUST00000102911.3
ENSMUST00000107646.2
Slc44a1

solute carrier family 44, member 1

chr10_+_13966268 2.392 ENSMUST00000015645.4
Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr7_-_44670820 2.349 ENSMUST00000048102.7
Myh14
myosin, heavy polypeptide 14
chr8_+_94179089 2.090 ENSMUST00000034215.6
Mt1
metallothionein 1
chr9_-_42399709 2.038 ENSMUST00000160940.1
Tecta
tectorin alpha
chr7_+_19176416 1.900 ENSMUST00000117338.1
Eml2
echinoderm microtubule associated protein like 2
chr10_-_33995054 1.832 ENSMUST00000164429.1
Gm17567
predicted gene, 17567
chr1_+_172341197 1.762 ENSMUST00000056136.3
Kcnj10
potassium inwardly-rectifying channel, subfamily J, member 10
chr15_+_80287234 1.723 ENSMUST00000160424.1
Cacna1i
calcium channel, voltage-dependent, alpha 1I subunit
chr7_-_105482197 1.557 ENSMUST00000047040.2
Prkcdbp
protein kinase C, delta binding protein
chr5_-_147725988 1.410 ENSMUST00000110529.1
ENSMUST00000031652.3
ENSMUST00000031653.5
Flt1


FMS-like tyrosine kinase 1


chr9_+_54538984 1.405 ENSMUST00000060242.5
ENSMUST00000118413.1
Sh2d7

SH2 domain containing 7

chr2_-_152951547 1.353 ENSMUST00000037715.6
Dusp15
dual specificity phosphatase-like 15
chrX_+_73064787 1.329 ENSMUST00000060418.6
Pnma3
paraneoplastic antigen MA3
chr6_+_4902913 1.316 ENSMUST00000175889.1
ENSMUST00000168998.2
Ppp1r9a

protein phosphatase 1, regulatory (inhibitor) subunit 9A

chr4_+_133039482 1.278 ENSMUST00000105914.1
Ahdc1
AT hook, DNA binding motif, containing 1
chr7_-_99695809 1.189 ENSMUST00000107086.2
Slco2b1
solute carrier organic anion transporter family, member 2b1
chr4_-_141664063 1.111 ENSMUST00000084203.4
Plekhm2
pleckstrin homology domain containing, family M (with RUN domain) member 2
chr2_-_152951688 1.077 ENSMUST00000109811.3
Dusp15
dual specificity phosphatase-like 15
chr1_+_75507077 1.022 ENSMUST00000037330.4
Inha
inhibin alpha
chr4_+_42916647 1.011 ENSMUST00000132173.1
ENSMUST00000107975.1
N28178

expressed sequence N28178

chr19_+_5474681 0.993 ENSMUST00000165485.1
ENSMUST00000166253.1
ENSMUST00000167371.1
ENSMUST00000167855.1
ENSMUST00000070118.7
Efemp2




epidermal growth factor-containing fibulin-like extracellular matrix protein 2




chr11_+_101552188 0.980 ENSMUST00000147239.1
Nbr1
neighbor of Brca1 gene 1
chr6_-_124769548 0.978 ENSMUST00000149652.1
ENSMUST00000112476.1
ENSMUST00000004378.8
Eno2


enolase 2, gamma neuronal


chr14_+_25459267 0.957 ENSMUST00000007961.8
Zmiz1
zinc finger, MIZ-type containing 1
chr14_-_26170283 0.931 ENSMUST00000100809.4
Plac9b
placenta specific 9b
chr1_+_36511867 0.891 ENSMUST00000001166.7
ENSMUST00000097776.3
Cnnm3

cyclin M3

chr15_+_86214431 0.876 ENSMUST00000063414.8
Tbc1d22a
TBC1 domain family, member 22a
chr5_-_116422858 0.856 ENSMUST00000036991.4
Hspb8
heat shock protein 8
chr15_-_98567630 0.838 ENSMUST00000012104.6
Ccnt1
cyclin T1
chr4_+_42917234 0.838 ENSMUST00000107976.2
ENSMUST00000069184.2
N28178

expressed sequence N28178

chr6_-_86793522 0.812 ENSMUST00000001187.8
Anxa4
annexin A4
chr19_+_6400523 0.809 ENSMUST00000146831.1
ENSMUST00000035716.8
ENSMUST00000138555.1
ENSMUST00000167240.1
Rasgrp2



RAS, guanyl releasing protein 2



chrX_-_102644210 0.797 ENSMUST00000052012.7
ENSMUST00000043596.5
ENSMUST00000119229.1
ENSMUST00000122022.1
ENSMUST00000120270.1
ENSMUST00000113611.2
Phka1





phosphorylase kinase alpha 1





chr12_-_98577940 0.774 ENSMUST00000110113.1
Kcnk10
potassium channel, subfamily K, member 10
chr10_-_78298162 0.768 ENSMUST00000105389.1
Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr11_+_101552135 0.755 ENSMUST00000103099.1
Nbr1
neighbor of Brca1 gene 1
chr19_+_44992127 0.749 ENSMUST00000179305.1
Sema4g
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr11_+_75513540 0.730 ENSMUST00000042808.6
ENSMUST00000118243.1
Scarf1

scavenger receptor class F, member 1

chr12_+_86678685 0.719 ENSMUST00000021681.3
Vash1
vasohibin 1
chr19_+_4594312 0.712 ENSMUST00000113825.2
Pcx
pyruvate carboxylase
chr9_-_58249702 0.703 ENSMUST00000135310.1
ENSMUST00000085673.4
ENSMUST00000114136.2
ENSMUST00000153820.1
ENSMUST00000124982.1
Pml




promyelocytic leukemia




chr2_-_120353094 0.682 ENSMUST00000028752.7
ENSMUST00000102501.3
Vps39

vacuolar protein sorting 39 (yeast)

chr14_+_46882854 0.670 ENSMUST00000022386.8
ENSMUST00000100672.3
Samd4

sterile alpha motif domain containing 4

chr3_-_108226598 0.659 ENSMUST00000029486.7
ENSMUST00000156371.1
ENSMUST00000141387.1
Sypl2


synaptophysin-like 2


chr2_+_32621750 0.648 ENSMUST00000113278.2
Ak1
adenylate kinase 1
chr9_+_108662098 0.647 ENSMUST00000035222.5
Slc25a20
solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20
chr5_-_36582381 0.635 ENSMUST00000141043.1
ENSMUST00000031094.8
Tbc1d14

TBC1 domain family, member 14

chr2_-_130638094 0.608 ENSMUST00000089561.3
ENSMUST00000110260.1
Lzts3

leucine zipper, putative tumor suppressor family member 3

chr7_-_105787544 0.593 ENSMUST00000078482.5
ENSMUST00000154659.1
Dchs1

dachsous 1 (Drosophila)

chr16_-_29962307 0.552 ENSMUST00000100016.3
Gm1968
predicted gene 1968
chr5_-_113800356 0.550 ENSMUST00000160374.1
ENSMUST00000067853.5
Tmem119

transmembrane protein 119

chr7_-_127936097 0.546 ENSMUST00000150591.1
Prss36
protease, serine, 36
chr9_-_20879718 0.543 ENSMUST00000043726.6
Angptl6
angiopoietin-like 6
chr6_+_4903298 0.535 ENSMUST00000035813.2
Ppp1r9a
protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr4_-_15149755 0.503 ENSMUST00000108273.1
Necab1
N-terminal EF-hand calcium binding protein 1
chr4_-_108406676 0.498 ENSMUST00000184609.1
Gpx7
glutathione peroxidase 7
chr13_+_40859768 0.496 ENSMUST00000110191.2
Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr13_+_74350313 0.490 ENSMUST00000160021.1
ENSMUST00000162672.1
ENSMUST00000162376.1
Ccdc127


coiled-coil domain containing 127


chr14_-_31206666 0.486 ENSMUST00000165981.1
ENSMUST00000171735.1
Nisch

nischarin

chr11_+_78037959 0.481 ENSMUST00000073660.6
Flot2
flotillin 2
chr7_+_28180226 0.481 ENSMUST00000172467.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr11_+_101552849 0.481 ENSMUST00000107213.1
ENSMUST00000107208.1
ENSMUST00000107212.1
ENSMUST00000127421.1
Nbr1



neighbor of Brca1 gene 1



chr2_+_176802233 0.462 ENSMUST00000132883.1
Gm14295
predicted gene 14295
chr2_+_176711933 0.453 ENSMUST00000108983.2
Gm14305
predicted gene 14305
chr9_-_63377835 0.439 ENSMUST00000034920.9
Map2k5
mitogen-activated protein kinase kinase 5
chr7_-_105787567 0.438 ENSMUST00000144189.1
Dchs1
dachsous 1 (Drosophila)
chr6_-_59426279 0.433 ENSMUST00000051065.4
Gprin3
GPRIN family member 3
chr11_+_97685794 0.430 ENSMUST00000107584.1
ENSMUST00000107585.2
Cisd3

CDGSH iron sulfur domain 3

chr15_+_76380492 0.429 ENSMUST00000096385.4
ENSMUST00000160728.1
ENSMUST00000162319.1
Mroh1


maestro heat-like repeat family member 1


chr2_-_176149825 0.424 ENSMUST00000109049.3
ENSMUST00000179349.1
Gm2004

predicted gene 2004

chr9_+_44107268 0.421 ENSMUST00000114821.2
ENSMUST00000114818.2
C1qtnf5

C1q and tumor necrosis factor related protein 5

chr2_-_175203061 0.390 ENSMUST00000165892.1
Gm14391
predicted gene 14391
chr8_-_71043040 0.385 ENSMUST00000170101.1
Gm17576
predicted gene, 17576
chr14_-_70766598 0.385 ENSMUST00000167242.1
ENSMUST00000022696.6
Xpo7

exportin 7

chr2_+_177004553 0.384 ENSMUST00000126358.1
Gm14419
predicted gene 14419
chr16_+_94370786 0.383 ENSMUST00000147046.1
ENSMUST00000149885.1
ENSMUST00000127667.1
ENSMUST00000119131.1
ENSMUST00000145883.1
Ttc3




tetratricopeptide repeat domain 3




chr4_+_117849193 0.377 ENSMUST00000132043.2
ENSMUST00000169990.1
Slc6a9

solute carrier family 6 (neurotransmitter transporter, glycine), member 9

chr9_+_44107286 0.373 ENSMUST00000152956.1
ENSMUST00000114815.1
C1qtnf5

C1q and tumor necrosis factor related protein 5

chr6_+_72414301 0.371 ENSMUST00000065906.7
Ggcx
gamma-glutamyl carboxylase
chr7_-_31055594 0.359 ENSMUST00000039909.6
Fxyd1
FXYD domain-containing ion transport regulator 1
chr11_-_74590065 0.357 ENSMUST00000145524.1
ENSMUST00000047488.7
Rap1gap2

RAP1 GTPase activating protein 2

chr5_-_140649018 0.352 ENSMUST00000042661.3
Ttyh3
tweety homolog 3 (Drosophila)
chr17_-_57087729 0.350 ENSMUST00000071135.5
Tubb4a
tubulin, beta 4A class IVA
chr7_+_44442398 0.349 ENSMUST00000058667.8
Lrrc4b
leucine rich repeat containing 4B
chr10_-_89732253 0.348 ENSMUST00000020109.3
Actr6
ARP6 actin-related protein 6
chr2_-_177202829 0.347 ENSMUST00000133301.1
Gm14410
predicted gene 14410
chr18_-_67449083 0.345 ENSMUST00000025408.8
Afg3l2
AFG3(ATPase family gene 3)-like 2 (yeast)
chr19_+_6400611 0.333 ENSMUST00000113467.1
Rasgrp2
RAS, guanyl releasing protein 2
chr16_+_32431225 0.331 ENSMUST00000115140.1
Pcyt1a
phosphate cytidylyltransferase 1, choline, alpha isoform
chr11_-_116199040 0.331 ENSMUST00000066587.5
Acox1
acyl-Coenzyme A oxidase 1, palmitoyl
chr11_-_116198701 0.299 ENSMUST00000072948.4
Acox1
acyl-Coenzyme A oxidase 1, palmitoyl
chr2_+_177762898 0.294 ENSMUST00000119838.2
Gm14322
predicted gene 14322
chrX_+_77511002 0.291 ENSMUST00000088217.5
Tbl1x
transducin (beta)-like 1 X-linked
chr9_+_22003035 0.282 ENSMUST00000115331.2
ENSMUST00000003493.7
Prkcsh

protein kinase C substrate 80K-H

chr16_+_94370618 0.281 ENSMUST00000117648.1
ENSMUST00000147352.1
ENSMUST00000150346.1
ENSMUST00000155692.1
ENSMUST00000153988.1
ENSMUST00000141856.1
ENSMUST00000152117.1
ENSMUST00000150097.1
ENSMUST00000122895.1
ENSMUST00000151770.1
Ttc3









tetratricopeptide repeat domain 3









chr13_-_38960498 0.280 ENSMUST00000167513.1
Slc35b3
solute carrier family 35, member B3
chr4_-_123116686 0.276 ENSMUST00000166337.1
Gm17244
predicted gene, 17244
chr10_+_4611971 0.276 ENSMUST00000105590.1
ENSMUST00000067086.7
Esr1

estrogen receptor 1 (alpha)

chr16_-_4523056 0.271 ENSMUST00000090500.3
ENSMUST00000023161.7
Srl

sarcalumenin

chr9_-_59353430 0.268 ENSMUST00000026265.6
Bbs4
Bardet-Biedl syndrome 4 (human)
chr11_+_75655873 0.254 ENSMUST00000108431.2
Myo1c
myosin IC
chr1_+_152954966 0.253 ENSMUST00000043313.8
Nmnat2
nicotinamide nucleotide adenylyltransferase 2
chr17_+_25133385 0.250 ENSMUST00000040729.2
Clcn7
chloride channel 7
chr9_-_58249660 0.224 ENSMUST00000124063.1
ENSMUST00000126690.1
Pml

promyelocytic leukemia

chr4_+_147507600 0.224 ENSMUST00000063704.7
Gm13152
predicted gene 13152
chr10_+_89686365 0.223 ENSMUST00000181598.1
1500026H17Rik
RIKEN cDNA 1500026H17 gene
chrX_+_101532734 0.217 ENSMUST00000118878.1
ENSMUST00000101341.2
ENSMUST00000149274.1
Taf1


TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor


chr14_-_31206782 0.209 ENSMUST00000022469.6
ENSMUST00000172142.1
Nisch

nischarin

chr2_+_91650116 0.191 ENSMUST00000111331.2
Arhgap1
Rho GTPase activating protein 1
chr2_+_181497223 0.179 ENSMUST00000108799.3
Tpd52l2
tumor protein D52-like 2
chr2_-_51934644 0.178 ENSMUST00000165313.1
Rbm43
RNA binding motif protein 43
chr14_+_34220028 0.178 ENSMUST00000119693.1
ENSMUST00000035351.5
Syt15

synaptotagmin XV

chr11_-_120630126 0.176 ENSMUST00000106180.1
Mafg
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr14_+_25459206 0.172 ENSMUST00000162645.1
Zmiz1
zinc finger, MIZ-type containing 1
chr2_+_181497165 0.160 ENSMUST00000149163.1
ENSMUST00000000844.8
ENSMUST00000184849.1
ENSMUST00000108800.1
ENSMUST00000069712.2
Tpd52l2




tumor protein D52-like 2




chr10_-_43901712 0.157 ENSMUST00000020012.6
Qrsl1
glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1
chr4_-_133672601 0.156 ENSMUST00000062118.4
ENSMUST00000067902.6
Pigv

phosphatidylinositol glycan anchor biosynthesis, class V

chr9_+_56994932 0.152 ENSMUST00000034832.6
Ptpn9
protein tyrosine phosphatase, non-receptor type 9
chr5_-_124531308 0.149 ENSMUST00000062153.7
Rilpl1
Rab interacting lysosomal protein-like 1
chr11_+_97685903 0.138 ENSMUST00000107583.2
Cisd3
CDGSH iron sulfur domain 3
chr16_-_20730544 0.134 ENSMUST00000076422.5
Thpo
thrombopoietin
chr1_-_163289214 0.125 ENSMUST00000183691.1
Prrx1
paired related homeobox 1
chr3_+_96181151 0.122 ENSMUST00000035371.8
Sv2a
synaptic vesicle glycoprotein 2 a
chr17_-_35909626 0.120 ENSMUST00000141132.1
Atat1
alpha tubulin acetyltransferase 1
chr17_-_47924400 0.116 ENSMUST00000113263.1
ENSMUST00000097311.2
Foxp4

forkhead box P4

chr2_+_176230177 0.115 ENSMUST00000135430.1
2210418O10Rik
RIKEN cDNA 2210418O10 gene
chr11_+_97050811 0.112 ENSMUST00000168565.1
Osbpl7
oxysterol binding protein-like 7
chr1_+_20951666 0.101 ENSMUST00000038447.4
Efhc1
EF-hand domain (C-terminal) containing 1
chr4_-_42581621 0.099 ENSMUST00000178742.1
Gm10592
predicted gene 10592
chr17_-_47924460 0.098 ENSMUST00000113262.1
Foxp4
forkhead box P4
chr10_+_116301374 0.095 ENSMUST00000092167.5
Ptprb
protein tyrosine phosphatase, receptor type, B
chr5_+_123076275 0.094 ENSMUST00000067505.8
ENSMUST00000111619.3
ENSMUST00000160344.1
Tmem120b


transmembrane protein 120B


chr11_+_97050594 0.093 ENSMUST00000090020.5
Osbpl7
oxysterol binding protein-like 7
chr11_-_74590186 0.093 ENSMUST00000102521.1
Rap1gap2
RAP1 GTPase activating protein 2
chr8_+_104831572 0.075 ENSMUST00000059449.6
Ces2b
carboxyesterase 2B
chr5_-_24445254 0.073 ENSMUST00000030800.6
Fastk
Fas-activated serine/threonine kinase
chr9_-_32541589 0.070 ENSMUST00000016231.7
Fli1
Friend leukemia integration 1
chr10_-_67548944 0.066 ENSMUST00000075686.4
Ado
2-aminoethanethiol (cysteamine) dioxygenase
chr4_-_42084291 0.063 ENSMUST00000177937.1
Gm21968
predicted gene, 21968
chr1_+_93215899 0.059 ENSMUST00000138595.1
E030010N08Rik
RIKEN cDNA E030010N08 gene
chr13_-_73678005 0.055 ENSMUST00000022105.7
ENSMUST00000109680.2
ENSMUST00000109679.2
Slc6a18


solute carrier family 6 (neurotransmitter transporter), member 18


chr4_-_42528175 0.046 ENSMUST00000180201.1
Gm13298
predicted gene 13298
chr3_+_94974831 0.035 ENSMUST00000167008.1
ENSMUST00000107251.2
Pi4kb

phosphatidylinositol 4-kinase, catalytic, beta polypeptide

chr14_+_21500879 0.033 ENSMUST00000182964.1
Kat6b
K(lysine) acetyltransferase 6B
chr9_+_44107226 0.013 ENSMUST00000114816.1
C1qtnf5
C1q and tumor necrosis factor related protein 5
chr11_+_5955693 0.010 ENSMUST00000002818.8
Ykt6
YKT6 homolog (S. Cerevisiae)
chr10_+_23894688 0.007 ENSMUST00000041416.7
Vnn1
vanin 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.9 GO:0007021 tubulin complex assembly(GO:0007021)
0.6 1.9 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.5 2.6 GO:0015871 choline transport(GO:0015871)
0.4 1.8 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.3 0.9 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.3 2.1 GO:0010273 detoxification of copper ion(GO:0010273) cellular response to zinc ion(GO:0071294) stress response to copper ion(GO:1990169)
0.3 1.9 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.3 1.0 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.2 0.7 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.2 1.4 GO:0048597 post-embryonic camera-type eye morphogenesis(GO:0048597)
0.2 1.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.2 0.7 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.2 1.0 GO:0046880 regulation of follicle-stimulating hormone secretion(GO:0046880) follicle-stimulating hormone secretion(GO:0046884)
0.2 1.1 GO:0007296 vitellogenesis(GO:0007296)
0.2 0.5 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.2 0.6 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.1 0.4 GO:0070375 ERK5 cascade(GO:0070375)
0.1 0.7 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.1 0.8 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.1 0.4 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 0.2 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.1 1.2 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.3 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1 0.6 GO:0006172 ADP biosynthetic process(GO:0006172)
0.1 0.6 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.1 0.5 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.6 GO:0015879 carnitine transport(GO:0015879)
0.1 0.5 GO:1903012 positive regulation of bone development(GO:1903012)
0.1 0.8 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 0.8 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 2.3 GO:0071625 vocalization behavior(GO:0071625)
0.1 0.3 GO:0060745 Sertoli cell proliferation(GO:0060011) mammary gland branching involved in pregnancy(GO:0060745)
0.1 0.3 GO:1903546 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108) protein localization to photoreceptor outer segment(GO:1903546)
0.1 1.7 GO:0030431 sleep(GO:0030431)
0.1 0.3 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1 0.4 GO:1903275 positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278) regulation of inorganic anion transmembrane transport(GO:1903795)
0.1 0.7 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.1 0.3 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.3 GO:0014874 response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.0 0.3 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 2.2 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.2 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706) negative regulation of vacuolar transport(GO:1903336)
0.0 0.1 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.1 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.0 0.1 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.7 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 1.1 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.2 GO:1901250 regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250)
0.0 0.1 GO:0071397 cellular response to cholesterol(GO:0071397)
0.0 0.3 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 2.2 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.7 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.8 GO:0070206 protein trimerization(GO:0070206)
0.0 2.4 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 0.7 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.3 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.9 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.5 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.1 GO:0048664 neuron fate determination(GO:0048664)
0.0 1.0 GO:0006096 glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757)
0.0 0.1 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.9 GO:0097512 cardiac myofibril(GO:0097512)
0.4 2.3 GO:0097513 myosin II filament(GO:0097513)
0.4 1.9 GO:1990761 growth cone lamellipodium(GO:1990761)
0.3 1.0 GO:0043512 inhibin-betaglycan-ActRII complex(GO:0034673) inhibin A complex(GO:0043512)
0.2 0.9 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 1.8 GO:0097449 astrocyte projection(GO:0097449)
0.1 0.8 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 1.0 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.3 GO:0005745 m-AAA complex(GO:0005745)
0.1 0.3 GO:0045160 myosin I complex(GO:0045160)
0.1 0.6 GO:0001520 outer dense fiber(GO:0001520)
0.1 0.8 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1 0.5 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 2.2 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 0.7 GO:0030123 AP-3 adaptor complex(GO:0030123) HOPS complex(GO:0030897)
0.0 0.3 GO:0033269 internode region of axon(GO:0033269)
0.0 0.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.8 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.2 GO:0097443 sorting endosome(GO:0097443)
0.0 0.2 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.3 GO:0034464 BBSome(GO:0034464)
0.0 2.1 GO:0072686 mitotic spindle(GO:0072686)
0.0 1.2 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.7 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.8 GO:0005776 autophagosome(GO:0005776)
0.0 0.2 GO:0045120 pronucleus(GO:0045120)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.6 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.6 1.8 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.4 3.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.4 1.7 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.2 1.4 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.2 2.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.2 1.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.2 0.5 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.2 0.6 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.1 0.5 GO:0004096 catalase activity(GO:0004096)
0.1 0.7 GO:0009374 biotin binding(GO:0009374)
0.1 0.8 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 1.0 GO:0034711 inhibin binding(GO:0034711)
0.1 1.0 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.6 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.1 0.8 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.3 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 0.3 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 0.2 GO:0001129 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.1 0.9 GO:0050897 cobalt ion binding(GO:0050897)
0.1 0.8 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.3 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1 1.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.6 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 2.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 2.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 2.1 GO:0005507 copper ion binding(GO:0005507)
0.0 0.7 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.3 GO:0034452 dynactin binding(GO:0034452)
0.0 0.8 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 2.0 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.3 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.7 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 1.1 GO:0019894 kinesin binding(GO:0019894)
0.0 0.5 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.2 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.5 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.5 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.6 GO:0043621 protein self-association(GO:0043621)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 0.9 PID_MYC_PATHWAY C-MYC pathway
0.0 1.1 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 3.0 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.1 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 0.5 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.4 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.1 1.2 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.1 2.9 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 1.4 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 0.8 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 2.3 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.6 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.0 1.8 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.4 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.8 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 1.7 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.6 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.6 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.8 REACTOME_ELONGATION_ARREST_AND_RECOVERY Genes involved in Elongation arrest and recovery
0.0 1.0 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.6 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.8 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.3 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.3 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA