Motif ID: Crem_Jdp2
Z-value: 0.550


Transcription factors associated with Crem_Jdp2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Crem | ENSMUSG00000063889.10 | Crem |
Jdp2 | ENSMUSG00000034271.9 | Jdp2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Crem | mm10_v2_chr18_-_3281036_3281132 | -0.30 | 5.8e-02 | Click! |
Jdp2 | mm10_v2_chr12_+_85599388_85599416 | -0.27 | 8.4e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.1 | 6.6 | GO:0021797 | forebrain anterior/posterior pattern specification(GO:0021797) |
1.0 | 3.0 | GO:0072284 | cervix development(GO:0060067) metanephric S-shaped body morphogenesis(GO:0072284) anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744) |
0.6 | 3.2 | GO:0048245 | eosinophil chemotaxis(GO:0048245) |
0.5 | 2.2 | GO:1902724 | positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728) |
0.4 | 1.3 | GO:0030070 | insulin processing(GO:0030070) |
0.4 | 1.3 | GO:1900020 | regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020) |
0.4 | 7.9 | GO:0031987 | locomotion involved in locomotory behavior(GO:0031987) |
0.4 | 1.2 | GO:0035973 | aggrephagy(GO:0035973) |
0.4 | 1.6 | GO:0042414 | epinephrine metabolic process(GO:0042414) |
0.4 | 1.5 | GO:0090467 | regulation of amino acid import(GO:0010958) L-arginine import(GO:0043091) arginine import(GO:0090467) |
0.3 | 2.5 | GO:0042487 | regulation of odontogenesis of dentin-containing tooth(GO:0042487) |
0.2 | 0.9 | GO:0060578 | extraocular skeletal muscle development(GO:0002074) subthalamic nucleus development(GO:0021763) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578) |
0.2 | 1.0 | GO:0003376 | sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520) |
0.2 | 0.5 | GO:0010845 | positive regulation of reciprocal meiotic recombination(GO:0010845) |
0.2 | 0.5 | GO:0006931 | substrate-dependent cell migration, cell attachment to substrate(GO:0006931) calcium-independent cell-matrix adhesion(GO:0007161) transforming growth factor-beta secretion(GO:0038044) |
0.1 | 1.0 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
0.1 | 0.7 | GO:0018125 | peptidyl-cysteine methylation(GO:0018125) |
0.1 | 1.1 | GO:0031547 | brain-derived neurotrophic factor receptor signaling pathway(GO:0031547) |
0.1 | 0.9 | GO:0055064 | carbon dioxide transport(GO:0015670) chloride ion homeostasis(GO:0055064) |
0.1 | 1.1 | GO:1904668 | positive regulation of ubiquitin protein ligase activity(GO:1904668) |
0.1 | 0.7 | GO:0098964 | dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964) |
0.1 | 1.3 | GO:0021942 | radial glia guided migration of Purkinje cell(GO:0021942) |
0.1 | 0.5 | GO:1904672 | regulation of somatic stem cell population maintenance(GO:1904672) |
0.1 | 0.6 | GO:2000271 | positive regulation of fibroblast apoptotic process(GO:2000271) |
0.1 | 0.3 | GO:0003221 | right ventricular cardiac muscle tissue morphogenesis(GO:0003221) |
0.1 | 0.8 | GO:0008635 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635) |
0.1 | 0.3 | GO:0014028 | notochord formation(GO:0014028) axial mesoderm morphogenesis(GO:0048319) |
0.1 | 1.2 | GO:0001682 | tRNA 5'-leader removal(GO:0001682) |
0.1 | 0.7 | GO:2000286 | receptor internalization involved in canonical Wnt signaling pathway(GO:2000286) |
0.1 | 0.5 | GO:1902775 | mitochondrial large ribosomal subunit assembly(GO:1902775) |
0.1 | 0.3 | GO:0031038 | myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519) |
0.1 | 0.3 | GO:0071335 | hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338) |
0.1 | 0.2 | GO:0034773 | histone H4-K20 trimethylation(GO:0034773) |
0.1 | 1.0 | GO:0006824 | cobalt ion transport(GO:0006824) |
0.1 | 0.2 | GO:0048294 | negative regulation of isotype switching to IgE isotypes(GO:0048294) |
0.1 | 0.2 | GO:0046341 | CDP-diacylglycerol metabolic process(GO:0046341) |
0.1 | 0.4 | GO:0032792 | negative regulation of CREB transcription factor activity(GO:0032792) |
0.1 | 0.6 | GO:0000320 | re-entry into mitotic cell cycle(GO:0000320) |
0.1 | 0.9 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
0.1 | 0.2 | GO:0045658 | regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659) |
0.1 | 0.2 | GO:0097278 | transforming growth factor beta activation(GO:0036363) complement-dependent cytotoxicity(GO:0097278) |
0.1 | 0.5 | GO:0060040 | retinal bipolar neuron differentiation(GO:0060040) |
0.1 | 0.2 | GO:0035694 | mitochondrial protein catabolic process(GO:0035694) |
0.1 | 0.8 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
0.1 | 1.4 | GO:0070262 | peptidyl-serine dephosphorylation(GO:0070262) |
0.1 | 0.2 | GO:0097401 | synaptic vesicle lumen acidification(GO:0097401) |
0.1 | 0.6 | GO:0033299 | secretion of lysosomal enzymes(GO:0033299) |
0.1 | 0.2 | GO:0000973 | posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) |
0.1 | 0.2 | GO:0019046 | release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382) |
0.1 | 0.4 | GO:0051012 | microtubule sliding(GO:0051012) |
0.1 | 0.6 | GO:0046543 | development of secondary female sexual characteristics(GO:0046543) |
0.1 | 0.2 | GO:1903753 | negative regulation of p38MAPK cascade(GO:1903753) |
0.1 | 0.7 | GO:0051152 | positive regulation of smooth muscle cell differentiation(GO:0051152) |
0.1 | 0.2 | GO:2000850 | negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850) |
0.1 | 1.0 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
0.1 | 0.7 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
0.1 | 0.3 | GO:0090164 | asymmetric Golgi ribbon formation(GO:0090164) |
0.1 | 0.7 | GO:0061469 | regulation of type B pancreatic cell proliferation(GO:0061469) |
0.1 | 0.6 | GO:0036123 | histone H3-K9 dimethylation(GO:0036123) |
0.1 | 0.5 | GO:0060373 | regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371) regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373) |
0.1 | 0.3 | GO:0018377 | N-terminal protein myristoylation(GO:0006499) protein myristoylation(GO:0018377) |
0.1 | 0.3 | GO:0034196 | acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) |
0.1 | 0.3 | GO:0034162 | toll-like receptor 9 signaling pathway(GO:0034162) |
0.1 | 0.7 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
0.1 | 0.9 | GO:0046855 | inositol phosphate dephosphorylation(GO:0046855) |
0.1 | 0.6 | GO:0060501 | positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) |
0.1 | 0.2 | GO:0097212 | cleavage furrow ingression(GO:0036090) lysosomal membrane organization(GO:0097212) |
0.1 | 0.4 | GO:0007296 | vitellogenesis(GO:0007296) |
0.1 | 0.2 | GO:0045204 | MAPK export from nucleus(GO:0045204) |
0.0 | 2.0 | GO:0001709 | cell fate determination(GO:0001709) |
0.0 | 0.1 | GO:0033566 | gamma-tubulin complex localization(GO:0033566) |
0.0 | 1.0 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
0.0 | 0.3 | GO:0070365 | hepatocyte differentiation(GO:0070365) |
0.0 | 0.2 | GO:1903546 | protein localization to photoreceptor outer segment(GO:1903546) |
0.0 | 0.1 | GO:0051030 | snRNA transport(GO:0051030) |
0.0 | 0.2 | GO:0001844 | protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:0001844) |
0.0 | 0.2 | GO:0001306 | age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571) |
0.0 | 0.1 | GO:2000501 | natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501) |
0.0 | 0.2 | GO:0051661 | cortical microtubule organization(GO:0043622) maintenance of centrosome location(GO:0051661) |
0.0 | 1.0 | GO:0051457 | maintenance of protein location in nucleus(GO:0051457) |
0.0 | 0.1 | GO:0060279 | positive regulation of ovulation(GO:0060279) |
0.0 | 0.6 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
0.0 | 0.0 | GO:0045829 | negative regulation of isotype switching(GO:0045829) |
0.0 | 0.5 | GO:0006706 | steroid catabolic process(GO:0006706) |
0.0 | 0.2 | GO:0019065 | receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509) |
0.0 | 0.7 | GO:0080182 | histone H3-K4 trimethylation(GO:0080182) |
0.0 | 0.5 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
0.0 | 0.1 | GO:0045014 | detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594) |
0.0 | 0.1 | GO:0071707 | immunoglobulin heavy chain V-D-J recombination(GO:0071707) |
0.0 | 0.1 | GO:1902412 | regulation of mitotic cytokinesis(GO:1902412) |
0.0 | 0.2 | GO:0071947 | protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) |
0.0 | 0.1 | GO:0046604 | positive regulation of mitotic centrosome separation(GO:0046604) |
0.0 | 0.7 | GO:0070208 | protein heterotrimerization(GO:0070208) |
0.0 | 0.4 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
0.0 | 0.1 | GO:0008616 | queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116) |
0.0 | 0.2 | GO:0032790 | ribosome disassembly(GO:0032790) |
0.0 | 0.5 | GO:0032515 | negative regulation of phosphoprotein phosphatase activity(GO:0032515) |
0.0 | 0.8 | GO:0001706 | endoderm formation(GO:0001706) |
0.0 | 0.2 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
0.0 | 0.1 | GO:1900864 | mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864) |
0.0 | 0.2 | GO:0090315 | negative regulation of protein targeting to membrane(GO:0090315) |
0.0 | 0.2 | GO:0002098 | tRNA wobble uridine modification(GO:0002098) |
0.0 | 0.2 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
0.0 | 0.1 | GO:1901857 | positive regulation of cellular respiration(GO:1901857) regulation of progesterone biosynthetic process(GO:2000182) |
0.0 | 0.2 | GO:0000042 | protein targeting to Golgi(GO:0000042) |
0.0 | 0.3 | GO:0006107 | oxaloacetate metabolic process(GO:0006107) |
0.0 | 0.3 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
0.0 | 0.4 | GO:0034067 | protein localization to Golgi apparatus(GO:0034067) |
0.0 | 0.1 | GO:0015819 | lysine transport(GO:0015819) ornithine transport(GO:0015822) |
0.0 | 0.2 | GO:1902474 | positive regulation of protein localization to synapse(GO:1902474) |
0.0 | 0.1 | GO:0000972 | transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972) |
0.0 | 0.4 | GO:0031573 | intra-S DNA damage checkpoint(GO:0031573) |
0.0 | 0.2 | GO:0032875 | regulation of DNA endoreduplication(GO:0032875) DNA endoreduplication(GO:0042023) |
0.0 | 0.3 | GO:0048671 | negative regulation of collateral sprouting(GO:0048671) |
0.0 | 0.1 | GO:0018243 | protein O-linked glycosylation via threonine(GO:0018243) |
0.0 | 0.1 | GO:0044861 | protein transport into plasma membrane raft(GO:0044861) |
0.0 | 0.2 | GO:1901409 | positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
0.0 | 0.2 | GO:0061339 | establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339) |
0.0 | 0.1 | GO:0046601 | positive regulation of centriole replication(GO:0046601) |
0.0 | 0.1 | GO:0035864 | response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865) |
0.0 | 0.4 | GO:0010763 | positive regulation of fibroblast migration(GO:0010763) |
0.0 | 0.1 | GO:0061084 | regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084) |
0.0 | 0.3 | GO:0071625 | vocalization behavior(GO:0071625) |
0.0 | 0.2 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
0.0 | 0.1 | GO:1902741 | type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741) |
0.0 | 0.1 | GO:0030397 | membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081) |
0.0 | 0.7 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
0.0 | 0.1 | GO:0046007 | negative regulation of activated T cell proliferation(GO:0046007) |
0.0 | 0.0 | GO:2000686 | regulation of rubidium ion transmembrane transporter activity(GO:2000686) |
0.0 | 0.1 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
0.0 | 0.1 | GO:0060702 | negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) |
0.0 | 0.1 | GO:0050957 | equilibrioception(GO:0050957) |
0.0 | 0.1 | GO:0006072 | glycerol-3-phosphate metabolic process(GO:0006072) |
0.0 | 0.1 | GO:1902035 | positive regulation of hematopoietic stem cell proliferation(GO:1902035) |
0.0 | 0.1 | GO:0010793 | regulation of mRNA export from nucleus(GO:0010793) |
0.0 | 0.2 | GO:0046856 | phosphatidylinositol dephosphorylation(GO:0046856) |
0.0 | 0.4 | GO:0003016 | respiratory system process(GO:0003016) |
0.0 | 0.1 | GO:0006680 | glucosylceramide catabolic process(GO:0006680) |
0.0 | 0.2 | GO:0060213 | regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) |
0.0 | 0.1 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
0.0 | 0.4 | GO:0070584 | mitochondrion morphogenesis(GO:0070584) |
0.0 | 0.4 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
0.0 | 0.1 | GO:2000348 | regulation of CD40 signaling pathway(GO:2000348) |
0.0 | 0.1 | GO:0042985 | negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) |
0.0 | 0.2 | GO:0032460 | negative regulation of protein oligomerization(GO:0032460) negative regulation of protein homooligomerization(GO:0032463) |
0.0 | 0.3 | GO:0051123 | RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) |
0.0 | 0.1 | GO:0009644 | response to high light intensity(GO:0009644) |
0.0 | 0.2 | GO:0030953 | astral microtubule organization(GO:0030953) |
0.0 | 0.1 | GO:0006363 | termination of RNA polymerase I transcription(GO:0006363) |
0.0 | 0.0 | GO:0048014 | Tie signaling pathway(GO:0048014) |
0.0 | 0.2 | GO:0072395 | signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422) |
0.0 | 1.8 | GO:0010466 | negative regulation of peptidase activity(GO:0010466) |
0.0 | 0.2 | GO:0006622 | protein targeting to lysosome(GO:0006622) |
0.0 | 0.0 | GO:0097343 | ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026) |
0.0 | 0.6 | GO:0006940 | regulation of smooth muscle contraction(GO:0006940) |
0.0 | 0.0 | GO:0010815 | bradykinin catabolic process(GO:0010815) |
0.0 | 0.1 | GO:0055098 | response to low-density lipoprotein particle(GO:0055098) |
0.0 | 0.3 | GO:0016572 | histone phosphorylation(GO:0016572) |
0.0 | 0.1 | GO:0070940 | dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 1.6 | GO:0045009 | melanosome membrane(GO:0033162) chitosome(GO:0045009) |
0.4 | 1.3 | GO:0043224 | nuclear SCF ubiquitin ligase complex(GO:0043224) |
0.3 | 0.9 | GO:0034274 | Atg12-Atg5-Atg16 complex(GO:0034274) |
0.2 | 1.0 | GO:0031467 | Cul7-RING ubiquitin ligase complex(GO:0031467) |
0.2 | 0.7 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
0.2 | 1.2 | GO:0000172 | ribonuclease MRP complex(GO:0000172) |
0.2 | 0.5 | GO:0005577 | fibrinogen complex(GO:0005577) |
0.1 | 2.4 | GO:0031045 | dense core granule(GO:0031045) |
0.1 | 0.7 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
0.1 | 0.7 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
0.1 | 1.4 | GO:0030008 | TRAPP complex(GO:0030008) |
0.1 | 0.6 | GO:0010009 | cytoplasmic side of endosome membrane(GO:0010009) |
0.1 | 1.0 | GO:0071437 | invadopodium(GO:0071437) |
0.1 | 0.6 | GO:0030478 | actin cap(GO:0030478) |
0.1 | 0.9 | GO:0002178 | palmitoyltransferase complex(GO:0002178) |
0.1 | 0.2 | GO:0044614 | nuclear pore cytoplasmic filaments(GO:0044614) |
0.1 | 0.3 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
0.1 | 0.5 | GO:0033503 | HULC complex(GO:0033503) |
0.1 | 1.4 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
0.1 | 0.8 | GO:0072546 | ER membrane protein complex(GO:0072546) |
0.1 | 0.4 | GO:0070652 | HAUS complex(GO:0070652) |
0.1 | 0.3 | GO:0000235 | astral microtubule(GO:0000235) |
0.0 | 0.3 | GO:0000125 | PCAF complex(GO:0000125) |
0.0 | 0.2 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
0.0 | 0.0 | GO:0061574 | ASAP complex(GO:0061574) |
0.0 | 0.6 | GO:0044754 | secondary lysosome(GO:0005767) autolysosome(GO:0044754) |
0.0 | 0.6 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
0.0 | 0.3 | GO:0001940 | male pronucleus(GO:0001940) |
0.0 | 0.5 | GO:0044232 | organelle membrane contact site(GO:0044232) |
0.0 | 0.6 | GO:0031083 | BLOC-1 complex(GO:0031083) |
0.0 | 0.5 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
0.0 | 0.7 | GO:0035253 | ciliary rootlet(GO:0035253) |
0.0 | 0.2 | GO:0000322 | storage vacuole(GO:0000322) |
0.0 | 0.7 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.0 | 0.1 | GO:1990423 | RZZ complex(GO:1990423) |
0.0 | 1.3 | GO:0097546 | ciliary base(GO:0097546) |
0.0 | 0.1 | GO:0097447 | dendritic tree(GO:0097447) |
0.0 | 0.2 | GO:0005664 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
0.0 | 0.2 | GO:0042581 | specific granule(GO:0042581) |
0.0 | 0.2 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
0.0 | 0.1 | GO:0002139 | stereocilia coupling link(GO:0002139) |
0.0 | 0.3 | GO:0031528 | microvillus membrane(GO:0031528) |
0.0 | 0.1 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
0.0 | 0.3 | GO:0031985 | Golgi cisterna(GO:0031985) |
0.0 | 0.1 | GO:0000931 | gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274) |
0.0 | 0.4 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
0.0 | 0.2 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
0.0 | 0.1 | GO:0098536 | deuterosome(GO:0098536) |
0.0 | 0.2 | GO:0043196 | varicosity(GO:0043196) |
0.0 | 0.1 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
0.0 | 0.3 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
0.0 | 1.1 | GO:0005643 | nuclear pore(GO:0005643) |
0.0 | 0.2 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
0.0 | 0.1 | GO:0070847 | core mediator complex(GO:0070847) |
0.0 | 0.7 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
0.0 | 0.1 | GO:0060053 | neurofilament cytoskeleton(GO:0060053) |
0.0 | 0.8 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
0.0 | 1.1 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
0.0 | 2.6 | GO:0030141 | secretory granule(GO:0030141) |
0.0 | 0.5 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
0.0 | 1.0 | GO:0005769 | early endosome(GO:0005769) |
0.0 | 0.1 | GO:0060293 | P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293) |
0.0 | 0.1 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
0.0 | 0.2 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
0.0 | 0.5 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.3 | 7.9 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
0.6 | 4.2 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
0.4 | 1.2 | GO:0000171 | ribonuclease MRP activity(GO:0000171) |
0.3 | 1.6 | GO:0035240 | dopamine binding(GO:0035240) |
0.3 | 0.9 | GO:0019776 | Atg8 ligase activity(GO:0019776) |
0.3 | 0.8 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
0.3 | 2.3 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
0.3 | 1.5 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
0.2 | 0.7 | GO:0034190 | apolipoprotein receptor binding(GO:0034190) |
0.2 | 1.2 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
0.2 | 0.7 | GO:0031800 | type 3 metabotropic glutamate receptor binding(GO:0031800) |
0.2 | 1.3 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
0.1 | 3.2 | GO:0042056 | chemoattractant activity(GO:0042056) |
0.1 | 1.1 | GO:0048403 | brain-derived neurotrophic factor binding(GO:0048403) |
0.1 | 1.0 | GO:0038036 | sphingosine-1-phosphate receptor activity(GO:0038036) |
0.1 | 1.0 | GO:0015087 | cobalt ion transmembrane transporter activity(GO:0015087) |
0.1 | 1.2 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
0.1 | 0.6 | GO:1904047 | S-adenosyl-L-methionine binding(GO:1904047) |
0.1 | 0.2 | GO:0002135 | CTP binding(GO:0002135) |
0.1 | 1.1 | GO:0004445 | inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030) |
0.1 | 0.2 | GO:0004605 | phosphatidate cytidylyltransferase activity(GO:0004605) |
0.1 | 1.0 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
0.1 | 0.9 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
0.1 | 0.5 | GO:0045340 | mercury ion binding(GO:0045340) |
0.1 | 0.5 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
0.1 | 0.4 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
0.1 | 0.2 | GO:0070139 | ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139) |
0.1 | 2.2 | GO:0005109 | frizzled binding(GO:0005109) |
0.1 | 0.6 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
0.1 | 0.2 | GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616) |
0.1 | 0.3 | GO:0033192 | calmodulin-dependent protein phosphatase activity(GO:0033192) |
0.1 | 0.5 | GO:0051021 | GDP-dissociation inhibitor binding(GO:0051021) |
0.1 | 0.1 | GO:0097677 | STAT family protein binding(GO:0097677) |
0.1 | 0.9 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
0.1 | 0.7 | GO:0031996 | thioesterase binding(GO:0031996) |
0.1 | 0.4 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
0.1 | 0.2 | GO:0005093 | Rab GDP-dissociation inhibitor activity(GO:0005093) |
0.0 | 0.6 | GO:0001618 | virus receptor activity(GO:0001618) |
0.0 | 8.7 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
0.0 | 1.0 | GO:0097602 | cullin family protein binding(GO:0097602) |
0.0 | 1.5 | GO:0005112 | Notch binding(GO:0005112) |
0.0 | 2.6 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
0.0 | 0.6 | GO:0005355 | glucose transmembrane transporter activity(GO:0005355) |
0.0 | 1.8 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.0 | 0.7 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
0.0 | 0.2 | GO:0071987 | WD40-repeat domain binding(GO:0071987) |
0.0 | 0.2 | GO:0035614 | snRNA stem-loop binding(GO:0035614) |
0.0 | 0.2 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
0.0 | 0.4 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
0.0 | 0.3 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
0.0 | 0.2 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
0.0 | 0.2 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
0.0 | 0.9 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
0.0 | 0.7 | GO:0017160 | Ral GTPase binding(GO:0017160) |
0.0 | 1.0 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
0.0 | 0.1 | GO:0032564 | dATP binding(GO:0032564) |
0.0 | 0.2 | GO:0030957 | Tat protein binding(GO:0030957) |
0.0 | 0.2 | GO:0034483 | heparan sulfate sulfotransferase activity(GO:0034483) |
0.0 | 0.1 | GO:0070012 | oligopeptidase activity(GO:0070012) |
0.0 | 0.7 | GO:0003785 | actin monomer binding(GO:0003785) |
0.0 | 0.1 | GO:0008479 | queuine tRNA-ribosyltransferase activity(GO:0008479) |
0.0 | 0.2 | GO:0009019 | tRNA (guanine-N1-)-methyltransferase activity(GO:0009019) |
0.0 | 0.3 | GO:0019215 | intermediate filament binding(GO:0019215) |
0.0 | 0.1 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
0.0 | 1.0 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
0.0 | 0.2 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
0.0 | 0.1 | GO:0000064 | L-ornithine transmembrane transporter activity(GO:0000064) |
0.0 | 0.3 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
0.0 | 0.8 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
0.0 | 0.5 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
0.0 | 0.4 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
0.0 | 0.5 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
0.0 | 0.2 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
0.0 | 0.1 | GO:0051880 | G-quadruplex DNA binding(GO:0051880) |
0.0 | 0.6 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.0 | 0.1 | GO:0004348 | glucosylceramidase activity(GO:0004348) |
0.0 | 0.1 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
0.0 | 0.9 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
0.0 | 0.6 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
0.0 | 0.2 | GO:0016004 | phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229) |
0.0 | 0.4 | GO:0031489 | myosin V binding(GO:0031489) |
0.0 | 1.7 | GO:0001158 | enhancer sequence-specific DNA binding(GO:0001158) |
0.0 | 0.2 | GO:0003688 | DNA replication origin binding(GO:0003688) |
0.0 | 1.1 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.0 | 0.1 | GO:0060698 | endoribonuclease inhibitor activity(GO:0060698) |
0.0 | 0.1 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
0.0 | 0.2 | GO:0043008 | ATP-dependent protein binding(GO:0043008) |
0.0 | 0.3 | GO:0008307 | structural constituent of muscle(GO:0008307) |
0.0 | 0.1 | GO:0015217 | ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217) |
0.0 | 0.3 | GO:0034185 | apolipoprotein binding(GO:0034185) |
0.0 | 0.3 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
0.0 | 0.1 | GO:0071558 | histone demethylase activity (H3-K27 specific)(GO:0071558) |
0.0 | 0.6 | GO:0015485 | cholesterol binding(GO:0015485) |
0.0 | 0.2 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
0.0 | 1.6 | GO:0047485 | protein N-terminus binding(GO:0047485) |
0.0 | 0.2 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
0.0 | 0.3 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
0.0 | 0.1 | GO:0015643 | toxic substance binding(GO:0015643) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 5.9 | PID_TCR_CALCIUM_PATHWAY | Calcium signaling in the CD4+ TCR pathway |
0.1 | 2.2 | ST_STAT3_PATHWAY | STAT3 Pathway |
0.1 | 3.0 | PID_P38_MK2_PATHWAY | p38 signaling mediated by MAPKAP kinases |
0.1 | 0.9 | SA_REG_CASCADE_OF_CYCLIN_EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
0.1 | 2.0 | PID_P38_ALPHA_BETA_PATHWAY | Regulation of p38-alpha and p38-beta |
0.0 | 1.2 | SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES | Genes related to regulation of the actin cytoskeleton |
0.0 | 0.6 | PID_S1P_S1P2_PATHWAY | S1P2 pathway |
0.0 | 3.4 | WNT_SIGNALING | Genes related to Wnt-mediated signal transduction |
0.0 | 0.5 | PID_INTEGRIN5_PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
0.0 | 0.2 | SA_G1_AND_S_PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
0.0 | 0.3 | PID_EPHA2_FWD_PATHWAY | EPHA2 forward signaling |
0.0 | 0.2 | PID_VEGFR1_2_PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
0.0 | 0.8 | PID_HIV_NEF_PATHWAY | HIV-1 Nef: Negative effector of Fas and TNF-alpha |
0.0 | 0.6 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
0.0 | 0.3 | PID_WNT_NONCANONICAL_PATHWAY | Noncanonical Wnt signaling pathway |
0.0 | 0.4 | PID_AMB2_NEUTROPHILS_PATHWAY | amb2 Integrin signaling |
0.0 | 0.2 | PID_IL5_PATHWAY | IL5-mediated signaling events |
0.0 | 0.8 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
0.0 | 0.3 | PID_MYC_PATHWAY | C-MYC pathway |
0.0 | 0.3 | PID_SMAD2_3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
0.0 | 0.4 | PID_FOXM1_PATHWAY | FOXM1 transcription factor network |
0.0 | 0.2 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 2.2 | REACTOME_IL_6_SIGNALING | Genes involved in Interleukin-6 signaling |
0.1 | 1.6 | REACTOME_AMINE_DERIVED_HORMONES | Genes involved in Amine-derived hormones |
0.1 | 5.5 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
0.1 | 1.3 | REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING | Genes involved in Insulin Synthesis and Processing |
0.1 | 0.7 | REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS | Genes involved in p130Cas linkage to MAPK signaling for integrins |
0.1 | 1.8 | REACTOME_SMOOTH_MUSCLE_CONTRACTION | Genes involved in Smooth Muscle Contraction |
0.0 | 0.7 | REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
0.0 | 2.9 | REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
0.0 | 0.7 | REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
0.0 | 0.2 | REACTOME_THE_NLRP3_INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
0.0 | 1.0 | REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
0.0 | 0.2 | REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION | Genes involved in E2F-enabled inhibition of pre-replication complex formation |
0.0 | 0.3 | REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
0.0 | 0.3 | REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 | Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1 |
0.0 | 0.7 | REACTOME_G1_PHASE | Genes involved in G1 Phase |
0.0 | 0.8 | REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN | Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein |
0.0 | 0.3 | REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
0.0 | 0.4 | REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE | Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase |
0.0 | 0.9 | REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS | Genes involved in Intrinsic Pathway for Apoptosis |
0.0 | 0.7 | REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
0.0 | 0.3 | REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
0.0 | 0.6 | REACTOME_SIGNALING_BY_HIPPO | Genes involved in Signaling by Hippo |
0.0 | 0.3 | REACTOME_CD28_DEPENDENT_VAV1_PATHWAY | Genes involved in CD28 dependent Vav1 pathway |
0.0 | 0.1 | REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
0.0 | 0.5 | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
0.0 | 0.6 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
0.0 | 0.4 | REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |
0.0 | 0.2 | REACTOME_COPI_MEDIATED_TRANSPORT | Genes involved in COPI Mediated Transport |
0.0 | 1.1 | REACTOME_MITOTIC_PROMETAPHASE | Genes involved in Mitotic Prometaphase |
0.0 | 0.3 | REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
0.0 | 0.5 | REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
0.0 | 0.4 | REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS | Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements |
0.0 | 0.5 | REACTOME_MRNA_3_END_PROCESSING | Genes involved in mRNA 3'-end processing |