Motif ID: Cux1

Z-value: 0.665


Transcription factors associated with Cux1:

Gene SymbolEntrez IDGene Name
Cux1 ENSMUSG00000029705.11 Cux1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cux1mm10_v2_chr5_-_136567242_1365672870.462.5e-03Click!


Activity profile for motif Cux1.

activity profile for motif Cux1


Sorted Z-values histogram for motif Cux1

Sorted Z-values for motif Cux1



Network of associatons between targets according to the STRING database.



First level regulatory network of Cux1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_71528657 5.489 ENSMUST00000126400.1
Dlx1
distal-less homeobox 1
chr2_+_71529085 5.337 ENSMUST00000152711.1
Dlx1
distal-less homeobox 1
chr2_+_158610731 2.895 ENSMUST00000045738.4
Slc32a1
solute carrier family 32 (GABA vesicular transporter), member 1
chr8_+_12385769 2.708 ENSMUST00000080795.8
Gm5607
predicted gene 5607
chr7_-_103827922 2.406 ENSMUST00000023934.6
ENSMUST00000153218.1
Hbb-bs

hemoglobin, beta adult s chain

chr5_+_117841839 2.400 ENSMUST00000142742.2
Nos1
nitric oxide synthase 1, neuronal
chr2_+_22622183 2.342 ENSMUST00000028123.3
Gad2
glutamic acid decarboxylase 2
chr11_+_78499087 2.260 ENSMUST00000017488.4
Vtn
vitronectin
chr7_+_96210107 1.530 ENSMUST00000138760.1
Tenm4
teneurin transmembrane protein 4
chr3_+_98013503 1.510 ENSMUST00000079812.6
Notch2
notch 2
chr5_+_66968559 1.388 ENSMUST00000127184.1
Limch1
LIM and calponin homology domains 1
chr5_-_122050102 1.379 ENSMUST00000154139.1
Cux2
cut-like homeobox 2
chr5_+_66968961 1.285 ENSMUST00000132991.1
Limch1
LIM and calponin homology domains 1
chr4_+_119814495 1.152 ENSMUST00000106307.2
Hivep3
human immunodeficiency virus type I enhancer binding protein 3
chr4_-_143299463 1.019 ENSMUST00000119654.1
Pdpn
podoplanin
chr17_-_6782775 1.008 ENSMUST00000064234.6
Ezr
ezrin
chr7_-_19166119 0.976 ENSMUST00000094790.3
Gipr
gastric inhibitory polypeptide receptor
chr5_+_140607334 0.959 ENSMUST00000031555.1
Lfng
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr17_-_6449571 0.953 ENSMUST00000180035.1
Tmem181b-ps
transmembrane protein 181B, pseudogene
chr17_-_32166879 0.794 ENSMUST00000087723.3
Notch3
notch 3
chr7_-_19698206 0.787 ENSMUST00000172808.1
ENSMUST00000174191.1
Apoe

apolipoprotein E

chr3_-_53657339 0.773 ENSMUST00000091137.4
Frem2
Fras1 related extracellular matrix protein 2
chr7_-_19698383 0.771 ENSMUST00000173739.1
Apoe
apolipoprotein E
chr6_-_127151044 0.747 ENSMUST00000000188.8
Ccnd2
cyclin D2
chr15_-_67113909 0.736 ENSMUST00000092640.5
St3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chrX_+_7722267 0.718 ENSMUST00000125991.1
ENSMUST00000148624.1
Wdr45

WD repeat domain 45

chr11_-_42182924 0.690 ENSMUST00000020707.5
ENSMUST00000132971.1
Gabra1

gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1

chr3_-_66296807 0.686 ENSMUST00000029419.7
Veph1
ventricular zone expressed PH domain-containing 1
chr13_-_81633119 0.680 ENSMUST00000126444.1
ENSMUST00000128585.1
ENSMUST00000146749.1
ENSMUST00000095585.4
Gpr98



G protein-coupled receptor 98



chr9_-_40346290 0.675 ENSMUST00000121357.1
Gramd1b
GRAM domain containing 1B
chr12_+_108334341 0.672 ENSMUST00000021684.4
Cyp46a1
cytochrome P450, family 46, subfamily a, polypeptide 1
chr15_+_74516196 0.670 ENSMUST00000042035.9
Bai1
brain-specific angiogenesis inhibitor 1
chr15_-_37791993 0.669 ENSMUST00000168992.1
ENSMUST00000148652.1
Ncald

neurocalcin delta

chr16_-_91597636 0.640 ENSMUST00000023686.8
Tmem50b
transmembrane protein 50B
chr1_+_16688405 0.622 ENSMUST00000026881.4
Ly96
lymphocyte antigen 96
chrX_+_7722214 0.592 ENSMUST00000043045.2
ENSMUST00000116634.1
ENSMUST00000115689.3
ENSMUST00000131077.1
ENSMUST00000115688.1
ENSMUST00000116633.1
Wdr45





WD repeat domain 45





chr3_+_68572245 0.589 ENSMUST00000170788.2
Schip1
schwannomin interacting protein 1
chr16_-_4003750 0.565 ENSMUST00000171658.1
ENSMUST00000171762.1
Slx4

SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)

chr7_-_140154712 0.551 ENSMUST00000059241.7
Sprn
shadow of prion protein
chr18_+_77185979 0.549 ENSMUST00000075290.6
St8sia5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr7_-_93081027 0.532 ENSMUST00000098303.1
Gm9934
predicted gene 9934
chr6_-_92943485 0.511 ENSMUST00000113438.1
Adamts9
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 9
chr14_+_47001336 0.505 ENSMUST00000125113.1
Samd4
sterile alpha motif domain containing 4
chr7_+_25268387 0.504 ENSMUST00000169392.1
Cic
capicua homolog (Drosophila)
chr7_+_144838590 0.494 ENSMUST00000105898.1
Fgf3
fibroblast growth factor 3
chr15_+_25758755 0.488 ENSMUST00000131834.1
ENSMUST00000124966.1
Myo10

myosin X

chr9_+_114731177 0.469 ENSMUST00000035007.8
Cmtm6
CKLF-like MARVEL transmembrane domain containing 6
chr5_-_70842617 0.467 ENSMUST00000031119.1
Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr3_+_27984145 0.463 ENSMUST00000067757.4
Pld1
phospholipase D1
chr13_+_43615710 0.458 ENSMUST00000059986.2
Rnf182
ring finger protein 182
chr2_-_25224653 0.455 ENSMUST00000043584.4
Tubb4b
tubulin, beta 4B class IVB
chr10_-_117282262 0.454 ENSMUST00000092163.7
Lyz2
lysozyme 2
chr1_+_72583245 0.446 ENSMUST00000145868.1
ENSMUST00000133123.1
ENSMUST00000047615.8
Smarcal1


SWI/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1


chr7_+_140941550 0.438 ENSMUST00000079403.4
Athl1
ATH1, acid trehalase-like 1 (yeast)
chr10_+_62071014 0.434 ENSMUST00000053865.5
Gm5424
predicted gene 5424
chr8_-_13677575 0.415 ENSMUST00000117551.2
Rasa3
RAS p21 protein activator 3
chr1_-_119837613 0.402 ENSMUST00000064091.5
Ptpn4
protein tyrosine phosphatase, non-receptor type 4
chr7_-_99695809 0.397 ENSMUST00000107086.2
Slco2b1
solute carrier organic anion transporter family, member 2b1
chr3_-_85722474 0.396 ENSMUST00000119077.1
Fam160a1
family with sequence similarity 160, member A1
chr11_+_32286946 0.396 ENSMUST00000101387.3
Hbq1b
hemoglobin, theta 1B
chr3_+_89715016 0.394 ENSMUST00000098924.2
Adar
adenosine deaminase, RNA-specific
chr17_-_47833256 0.392 ENSMUST00000152455.1
ENSMUST00000035375.7
Mdfi

MyoD family inhibitor

chrX_-_94212638 0.388 ENSMUST00000113922.1
Eif2s3x
eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked
chr18_+_37484955 0.385 ENSMUST00000053856.4
Pcdhb17
protocadherin beta 17
chr19_-_57360668 0.383 ENSMUST00000181921.1
B230217O12Rik
RIKEN cDNA B230217O12 gene
chr17_-_87797994 0.381 ENSMUST00000055221.7
Kcnk12
potassium channel, subfamily K, member 12
chr5_+_24428208 0.378 ENSMUST00000115049.2
Slc4a2
solute carrier family 4 (anion exchanger), member 2
chr5_-_145201829 0.373 ENSMUST00000162220.1
ENSMUST00000031632.8
Zkscan14

zinc finger with KRAB and SCAN domains 14

chr14_+_121035194 0.368 ENSMUST00000135010.1
Farp1
FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived)
chr7_+_113207465 0.367 ENSMUST00000047321.7
Arntl
aryl hydrocarbon receptor nuclear translocator-like
chr10_-_32890462 0.364 ENSMUST00000092602.1
Nkain2
Na+/K+ transporting ATPase interacting 2
chr9_-_112232449 0.350 ENSMUST00000035085.5
Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr8_+_68880491 0.344 ENSMUST00000015712.8
Lpl
lipoprotein lipase
chr6_+_41605482 0.343 ENSMUST00000114732.2
Ephb6
Eph receptor B6
chr1_+_75436002 0.342 ENSMUST00000131545.1
ENSMUST00000141124.1
Gmppa

GDP-mannose pyrophosphorylase A

chr18_+_37447641 0.341 ENSMUST00000052387.3
Pcdhb14
protocadherin beta 14
chr11_+_96251100 0.326 ENSMUST00000129907.2
Gm53
predicted gene 53
chr9_+_92457369 0.323 ENSMUST00000034941.7
Plscr4
phospholipid scramblase 4
chrX_+_142227923 0.321 ENSMUST00000042329.5
Nxt2
nuclear transport factor 2-like export factor 2
chr8_+_36094828 0.320 ENSMUST00000110492.1
D8Ertd82e
DNA segment, Chr 8, ERATO Doi 82, expressed
chr4_-_62360524 0.315 ENSMUST00000107461.1
ENSMUST00000084528.3
Fkbp15

FK506 binding protein 15

chr6_-_88875035 0.312 ENSMUST00000145944.1
Podxl2
podocalyxin-like 2
chr11_+_70540260 0.309 ENSMUST00000018429.5
ENSMUST00000108557.3
ENSMUST00000108556.1
Pld2


phospholipase D2


chr18_-_15403680 0.304 ENSMUST00000079081.6
Aqp4
aquaporin 4
chr7_-_28962223 0.304 ENSMUST00000127210.1
Actn4
actinin alpha 4
chr17_-_33760306 0.304 ENSMUST00000173860.1
Rab11b
RAB11B, member RAS oncogene family
chr10_+_81628570 0.302 ENSMUST00000153573.1
ENSMUST00000119336.1
Ankrd24

ankyrin repeat domain 24

chr16_-_33967032 0.302 ENSMUST00000023510.6
Umps
uridine monophosphate synthetase
chr6_-_40436104 0.299 ENSMUST00000039008.6
ENSMUST00000101492.3
E330009J07Rik

RIKEN cDNA E330009J07 gene

chr12_-_91746020 0.296 ENSMUST00000166967.1
Ston2
stonin 2
chr11_+_69088490 0.295 ENSMUST00000021273.6
ENSMUST00000117780.1
Vamp2

vesicle-associated membrane protein 2

chr15_+_21111452 0.291 ENSMUST00000075132.6
Cdh12
cadherin 12
chr4_+_130107556 0.286 ENSMUST00000030563.5
Pef1
penta-EF hand domain containing 1
chr2_-_32694120 0.286 ENSMUST00000028148.4
Fpgs
folylpolyglutamyl synthetase
chr2_+_131491764 0.279 ENSMUST00000028806.5
ENSMUST00000110179.2
ENSMUST00000110189.2
ENSMUST00000110182.2
ENSMUST00000110183.2
ENSMUST00000110186.2
ENSMUST00000110188.1
Smox






spermine oxidase






chr7_-_74013676 0.277 ENSMUST00000026896.4
St8sia2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr5_-_43981757 0.276 ENSMUST00000061299.7
Fgfbp1
fibroblast growth factor binding protein 1
chr15_+_76660564 0.274 ENSMUST00000004294.10
Kifc2
kinesin family member C2
chr6_-_97617536 0.274 ENSMUST00000113355.2
Frmd4b
FERM domain containing 4B
chr10_+_103367748 0.273 ENSMUST00000074204.4
ENSMUST00000179636.1
Slc6a15

solute carrier family 6 (neurotransmitter transporter), member 15

chr8_+_85037151 0.271 ENSMUST00000166592.1
Tnpo2
transportin 2 (importin 3, karyopherin beta 2b)
chrX_+_142228177 0.270 ENSMUST00000112914.1
Nxt2
nuclear transport factor 2-like export factor 2
chr1_-_77515048 0.264 ENSMUST00000027451.6
Epha4
Eph receptor A4
chr1_+_43092588 0.262 ENSMUST00000039080.3
8430432A02Rik
RIKEN cDNA 8430432A02 gene
chr1_-_119837338 0.261 ENSMUST00000163435.1
Ptpn4
protein tyrosine phosphatase, non-receptor type 4
chr10_-_127121125 0.260 ENSMUST00000164259.1
ENSMUST00000080975.4
Os9

amplified in osteosarcoma

chr9_+_111271832 0.257 ENSMUST00000060711.5
Epm2aip1
EPM2A (laforin) interacting protein 1
chr7_-_132576372 0.257 ENSMUST00000084500.6
Oat
ornithine aminotransferase
chr5_+_3596066 0.257 ENSMUST00000006061.6
ENSMUST00000121291.1
ENSMUST00000142516.1
Pex1


peroxisomal biogenesis factor 1


chr4_-_62360436 0.256 ENSMUST00000084527.3
ENSMUST00000098033.3
Fkbp15

FK506 binding protein 15

chr13_-_92030897 0.253 ENSMUST00000149630.1
Rasgrf2
RAS protein-specific guanine nucleotide-releasing factor 2
chr9_+_56418624 0.253 ENSMUST00000034879.3
Hmg20a
high mobility group 20A
chr6_+_49367739 0.250 ENSMUST00000060561.8
ENSMUST00000121903.1
ENSMUST00000134786.1
Fam221a


family with sequence similarity 221, member A


chr19_+_34217588 0.249 ENSMUST00000119603.1
Stambpl1
STAM binding protein like 1
chr19_-_8819278 0.245 ENSMUST00000088092.5
Ttc9c
tetratricopeptide repeat domain 9C
chr7_-_104950441 0.245 ENSMUST00000179862.1
Gm5900
predicted pseudogene 5900
chr14_-_69284982 0.244 ENSMUST00000183882.1
ENSMUST00000037064.4
Slc25a37

solute carrier family 25, member 37

chr15_+_99392948 0.244 ENSMUST00000161250.1
ENSMUST00000160635.1
ENSMUST00000161778.1
Tmbim6


transmembrane BAX inhibitor motif containing 6


chr7_+_13278778 0.244 ENSMUST00000098814.4
ENSMUST00000146998.1
ENSMUST00000185145.1
Lig1


ligase I, DNA, ATP-dependent


chr10_+_81628702 0.243 ENSMUST00000129622.1
Ankrd24
ankyrin repeat domain 24
chrX_+_136741821 0.237 ENSMUST00000089350.4
BC065397
cDNA sequence BC065397
chr9_-_21312255 0.236 ENSMUST00000115433.3
ENSMUST00000003397.7
Ap1m2

adaptor protein complex AP-1, mu 2 subunit

chr11_-_97744659 0.236 ENSMUST00000018691.8
Pip4k2b
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chr9_-_77347816 0.235 ENSMUST00000184138.1
ENSMUST00000184006.1
ENSMUST00000185144.1
ENSMUST00000034910.9
Mlip



muscular LMNA-interacting protein



chrX_-_74393103 0.235 ENSMUST00000114142.1
ENSMUST00000114139.1
ENSMUST00000114141.1
Fam3a


family with sequence similarity 3, member A


chr3_+_99141068 0.233 ENSMUST00000004343.2
Wars2
tryptophanyl tRNA synthetase 2 (mitochondrial)
chr9_+_107554633 0.231 ENSMUST00000010211.4
Rassf1
Ras association (RalGDS/AF-6) domain family member 1
chr2_+_57238297 0.230 ENSMUST00000112618.2
ENSMUST00000028167.2
Gpd2

glycerol phosphate dehydrogenase 2, mitochondrial

chr15_-_78120011 0.226 ENSMUST00000019290.2
Cacng2
calcium channel, voltage-dependent, gamma subunit 2
chr7_-_35215248 0.226 ENSMUST00000118444.1
ENSMUST00000122409.1
Lrp3

low density lipoprotein receptor-related protein 3

chr8_+_84908560 0.221 ENSMUST00000003910.6
ENSMUST00000109744.1
Dnase2a

deoxyribonuclease II alpha

chr6_+_48554776 0.220 ENSMUST00000114545.1
ENSMUST00000153222.1
ENSMUST00000101436.2
Lrrc61


leucine rich repeat containing 61


chr3_+_89266552 0.219 ENSMUST00000040824.1
Dpm3
dolichyl-phosphate mannosyltransferase polypeptide 3
chr4_-_116144609 0.217 ENSMUST00000030469.4
Lurap1
leucine rich adaptor protein 1
chr2_-_148875452 0.216 ENSMUST00000028938.6
ENSMUST00000144845.1
Cst3

cystatin C

chr9_-_101034857 0.215 ENSMUST00000142676.1
ENSMUST00000149322.1
Pccb

propionyl Coenzyme A carboxylase, beta polypeptide

chr6_-_114969986 0.212 ENSMUST00000139640.1
Vgll4
vestigial like 4 (Drosophila)
chr1_+_34801704 0.211 ENSMUST00000047664.9
Arhgef4
Rho guanine nucleotide exchange factor (GEF) 4
chr1_-_45503282 0.211 ENSMUST00000086430.4
Col5a2
collagen, type V, alpha 2
chr11_+_75486813 0.210 ENSMUST00000018449.4
ENSMUST00000102510.1
ENSMUST00000131283.1
Prpf8


pre-mRNA processing factor 8


chr13_-_81710937 0.210 ENSMUST00000161920.1
ENSMUST00000048993.5
Polr3g

polymerase (RNA) III (DNA directed) polypeptide G

chr4_+_155831272 0.208 ENSMUST00000139651.1
ENSMUST00000084097.5
Aurkaip1

aurora kinase A interacting protein 1

chr1_-_5019342 0.206 ENSMUST00000002533.8
Rgs20
regulator of G-protein signaling 20
chr14_+_70577839 0.205 ENSMUST00000089049.2
Nudt18
nudix (nucleoside diphosphate linked moiety X)-type motif 18
chr5_-_3596071 0.204 ENSMUST00000121877.1
Rbm48
RNA binding motif protein 48
chr2_+_129100995 0.204 ENSMUST00000103205.4
ENSMUST00000028874.7
Polr1b

polymerase (RNA) I polypeptide B

chr4_-_149126688 0.204 ENSMUST00000030815.2
Cort
cortistatin
chr1_+_87404916 0.203 ENSMUST00000173152.1
ENSMUST00000173663.1
Gigyf2

GRB10 interacting GYF protein 2

chr10_+_79960145 0.200 ENSMUST00000045247.7
Wdr18
WD repeat domain 18
chr7_+_46033698 0.197 ENSMUST00000033121.6
Nomo1
nodal modulator 1
chr8_-_73353477 0.197 ENSMUST00000119826.1
Large
like-glycosyltransferase
chr16_-_90934802 0.195 ENSMUST00000023694.3
1110004E09Rik
RIKEN cDNA 1110004E09 gene
chr11_+_115765420 0.195 ENSMUST00000093912.4
ENSMUST00000136720.1
ENSMUST00000103034.3
ENSMUST00000141871.1
2310067B10Rik



RIKEN cDNA 2310067B10 gene



chr8_-_8639363 0.195 ENSMUST00000152698.1
Efnb2
ephrin B2
chr8_-_102865853 0.194 ENSMUST00000076373.6
Gm8730
predicted pseudogene 8730
chr18_-_38211957 0.193 ENSMUST00000159405.1
ENSMUST00000160721.1
Pcdh1

protocadherin 1

chr1_+_165302625 0.192 ENSMUST00000111450.1
Gpr161
G protein-coupled receptor 161
chr19_-_46395722 0.191 ENSMUST00000040270.4
Actr1a
ARP1 actin-related protein 1A, centractin alpha
chr3_+_95624971 0.191 ENSMUST00000058230.6
ENSMUST00000037983.4
Ensa

endosulfine alpha

chr17_-_85090204 0.190 ENSMUST00000072406.3
ENSMUST00000171795.1
Prepl

prolyl endopeptidase-like

chr11_-_60352869 0.190 ENSMUST00000095254.5
ENSMUST00000102683.4
ENSMUST00000093048.6
ENSMUST00000093046.6
ENSMUST00000064019.8
ENSMUST00000102682.4
Tom1l2





target of myb1-like 2 (chicken)





chr7_+_24587543 0.189 ENSMUST00000077191.6
Ethe1
ethylmalonic encephalopathy 1
chr2_-_24049389 0.188 ENSMUST00000051416.5
Hnmt
histamine N-methyltransferase
chrX_-_74393211 0.187 ENSMUST00000122894.1
ENSMUST00000114143.3
Fam3a

family with sequence similarity 3, member A

chr8_+_84689308 0.187 ENSMUST00000125370.3
ENSMUST00000175784.1
Trmt1

tRNA methyltransferase 1

chrX_-_7947763 0.186 ENSMUST00000154244.1
Hdac6
histone deacetylase 6
chr4_+_108847827 0.185 ENSMUST00000102738.2
Kti12
KTI12 homolog, chromatin associated (S. cerevisiae)
chr13_-_66852017 0.185 ENSMUST00000059329.6
Gm17449
predicted gene, 17449
chr6_+_71831441 0.184 ENSMUST00000171057.1
Immt
inner membrane protein, mitochondrial
chrX_+_7884244 0.184 ENSMUST00000115663.3
Slc35a2
solute carrier family 35 (UDP-galactose transporter), member A2
chr11_-_45955465 0.183 ENSMUST00000011398.6
Thg1l
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr2_-_167060417 0.183 ENSMUST00000155281.1
Znfx1
zinc finger, NFX1-type containing 1
chr5_-_84417359 0.183 ENSMUST00000113401.1
Epha5
Eph receptor A5
chr11_+_32300069 0.181 ENSMUST00000020535.1
Hbq1a
hemoglobin, theta 1A
chr8_+_12757002 0.180 ENSMUST00000033818.3
ENSMUST00000091237.5
Atp11a

ATPase, class VI, type 11A

chr1_-_84935089 0.180 ENSMUST00000027422.5
Slc16a14
solute carrier family 16 (monocarboxylic acid transporters), member 14
chr13_-_114932035 0.179 ENSMUST00000056117.8
Itga2
integrin alpha 2
chr10_+_67096456 0.179 ENSMUST00000174317.1
Jmjd1c
jumonji domain containing 1C
chr7_-_140955960 0.178 ENSMUST00000081649.8
Ifitm2
interferon induced transmembrane protein 2
chr11_+_74649462 0.176 ENSMUST00000092915.5
ENSMUST00000117818.1
Cluh

clustered mitochondria (cluA/CLU1) homolog

chr9_-_112185726 0.176 ENSMUST00000160240.1
ENSMUST00000162065.1
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr15_+_84192223 0.176 ENSMUST00000023071.6
Samm50
sorting and assembly machinery component 50 homolog (S. cerevisiae)
chr4_-_155869394 0.176 ENSMUST00000105586.1
ENSMUST00000030950.1
Gltpd1

glycolipid transfer protein domain containing 1

chr1_+_179546303 0.175 ENSMUST00000040706.8
Cnst
consortin, connexin sorting protein
chr2_-_178414460 0.175 ENSMUST00000058678.4
Ppp1r3d
protein phosphatase 1, regulatory subunit 3D
chr2_+_180967291 0.175 ENSMUST00000108859.1
Arfgap1
ADP-ribosylation factor GTPase activating protein 1
chr5_+_110544326 0.173 ENSMUST00000040001.7
Galnt9
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9
chr3_+_19957037 0.173 ENSMUST00000091309.5
ENSMUST00000108329.1
ENSMUST00000003714.6
Cp


ceruloplasmin


chr11_+_101733011 0.172 ENSMUST00000129741.1
Dhx8
DEAH (Asp-Glu-Ala-His) box polypeptide 8
chr7_-_13054665 0.171 ENSMUST00000182515.1
ENSMUST00000069289.8
Mzf1

myeloid zinc finger 1

chr2_+_131909951 0.169 ENSMUST00000124100.1
ENSMUST00000136783.1
PRND

prion protein gene complex (Prn), transcript variant 1, mRNA

chr13_-_34130345 0.167 ENSMUST00000075774.3
Tubb2b
tubulin, beta 2B class IIB
chr5_-_148928619 0.166 ENSMUST00000149169.1
ENSMUST00000047257.8
Katnal1

katanin p60 subunit A-like 1

chr9_+_21337828 0.166 ENSMUST00000034697.7
Slc44a2
solute carrier family 44, member 2
chr10_+_79669410 0.166 ENSMUST00000020552.5
Tpgs1
tubulin polyglutamylase complex subunit 1
chr4_-_64276595 0.166 ENSMUST00000141162.1
Gm11217
predicted gene 11217
chr11_-_78536235 0.166 ENSMUST00000017759.2
ENSMUST00000108277.2
Tnfaip1

tumor necrosis factor, alpha-induced protein 1 (endothelial)

chrX_-_74393003 0.163 ENSMUST00000015427.6
Fam3a
family with sequence similarity 3, member A
chr19_-_5964132 0.162 ENSMUST00000025752.7
ENSMUST00000165143.1
Pola2

polymerase (DNA directed), alpha 2

chr11_+_108921648 0.160 ENSMUST00000144511.1
Axin2
axin2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 10.8 GO:0061075 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.8 2.4 GO:0099548 drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738) retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by nitric oxide(GO:0099548)
0.5 1.6 GO:1990705 cholangiocyte proliferation(GO:1990705)
0.5 1.6 GO:1903002 regulation of lipid transport across blood brain barrier(GO:1903000) positive regulation of lipid transport across blood brain barrier(GO:1903002)
0.4 2.2 GO:0006538 glutamate catabolic process(GO:0006538)
0.4 1.5 GO:0032289 central nervous system myelin formation(GO:0032289)
0.3 1.0 GO:1900041 intestinal D-glucose absorption(GO:0001951) negative regulation of interleukin-2 secretion(GO:1900041) terminal web assembly(GO:1902896)
0.3 2.9 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.2 1.0 GO:1901731 positive regulation of platelet aggregation(GO:1901731)
0.2 0.6 GO:1905034 regulation of antifungal innate immune response(GO:1905034) negative regulation of antifungal innate immune response(GO:1905035)
0.2 1.0 GO:0007386 compartment pattern specification(GO:0007386)
0.2 2.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.2 0.6 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.2 0.3 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.2 0.8 GO:0072103 glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.2 0.5 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 0.7 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 0.4 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.1 0.6 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.1 0.4 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.1 0.1 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.1 0.3 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.1 0.3 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.1 0.3 GO:0002447 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
0.1 0.3 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.1 0.3 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1 1.3 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 0.3 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.1 0.3 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1 0.2 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 0.7 GO:0071420 cellular response to histamine(GO:0071420)
0.1 0.3 GO:0045054 constitutive secretory pathway(GO:0045054)
0.1 0.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.2 GO:0009182 purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066) GDP metabolic process(GO:0046710)
0.1 0.5 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 0.2 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.1 0.2 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.1 0.2 GO:0070844 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.1 0.3 GO:0070295 renal water absorption(GO:0070295)
0.1 1.4 GO:0007614 short-term memory(GO:0007614)
0.1 0.2 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.1 0.7 GO:0071481 cellular response to X-ray(GO:0071481)
0.1 0.3 GO:0046208 spermine catabolic process(GO:0046208)
0.1 0.5 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.1 0.3 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 0.2 GO:2000054 regulation of chondrocyte development(GO:0061181) negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.1 0.2 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.0 0.2 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.2 GO:0001692 histamine metabolic process(GO:0001692) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.1 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.1 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 1.3 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
0.0 0.3 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.2 GO:0072737 response to diamide(GO:0072737) cellular response to diamide(GO:0072738)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.2 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.3 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.1 GO:0019659 fermentation(GO:0006113) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.0 0.2 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.4 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.2 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.1 GO:0000389 generation of catalytic spliceosome for second transesterification step(GO:0000350) mRNA 3'-splice site recognition(GO:0000389)
0.0 0.4 GO:1902913 positive regulation of melanocyte differentiation(GO:0045636) positive regulation of neuroepithelial cell differentiation(GO:1902913)
0.0 0.2 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
0.0 0.3 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.1 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.0 0.6 GO:0001553 luteinization(GO:0001553)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.2 GO:0010694 positive regulation of alkaline phosphatase activity(GO:0010694)
0.0 0.1 GO:0014042 positive regulation of neuron maturation(GO:0014042)
0.0 0.3 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.4 GO:0042407 cristae formation(GO:0042407)
0.0 0.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.5 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.2 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.2 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.2 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0046077 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) deoxyribonucleoside diphosphate metabolic process(GO:0009186) deoxyribonucleoside diphosphate biosynthetic process(GO:0009189) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.2 GO:1902669 positive regulation of axon guidance(GO:1902669)
0.0 0.2 GO:0070813 hydrogen sulfide metabolic process(GO:0070813)
0.0 0.2 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.0 0.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.0 1.0 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.4 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.4 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.2 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.5 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.1 GO:0021508 floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
0.0 0.1 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.1 GO:1903542 negative regulation of exosomal secretion(GO:1903542)
0.0 0.2 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.0 0.7 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.1 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.1 GO:1990927 negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927)
0.0 0.2 GO:0046688 response to copper ion(GO:0046688)
0.0 0.2 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.2 GO:0045187 regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.3 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.4 GO:0031297 replication fork processing(GO:0031297)
0.0 0.1 GO:0072719 cellular response to cisplatin(GO:0072719)
0.0 0.1 GO:0010873 positive regulation of cholesterol esterification(GO:0010873)
0.0 0.1 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.2 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 3.0 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.0 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.0 0.2 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.0 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.1 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.0 0.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.2 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 0.3 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 0.2 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 0.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.8 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.0 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.2 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0043589 skin morphogenesis(GO:0043589)
0.0 1.0 GO:0035308 negative regulation of protein dephosphorylation(GO:0035308)
0.0 0.1 GO:0060253 negative regulation of glial cell proliferation(GO:0060253)
0.0 0.2 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.0 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.0 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.7 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.1 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0 0.2 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.1 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.1 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.2 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.4 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.6 2.9 GO:0044316 cone cell pedicle(GO:0044316)
0.5 2.7 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.5 1.6 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.3 1.0 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.2 2.4 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.2 0.7 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 0.6 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 1.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.3 GO:0042627 chylomicron(GO:0042627)
0.1 0.7 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.7 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 0.3 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.3 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.4 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.2 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.1 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 1.8 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.4 GO:0033391 chromatoid body(GO:0033391)
0.0 0.5 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:0034657 GID complex(GO:0034657)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.1 GO:0034679 integrin alpha9-beta1 complex(GO:0034679)
0.0 0.3 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.3 GO:0031143 pseudopodium(GO:0031143)
0.0 0.2 GO:0002177 manchette(GO:0002177)
0.0 0.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 0.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.1 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.2 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.1 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.5 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.1 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 1.1 GO:0005604 basement membrane(GO:0005604)
0.0 0.6 GO:0009925 basal plasma membrane(GO:0009925)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.8 2.4 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.6 2.4 GO:0031720 haptoglobin binding(GO:0031720)
0.5 1.6 GO:0046911 hydroxyapatite binding(GO:0046848) metal chelating activity(GO:0046911) phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.3 2.3 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.3 1.0 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2 0.6 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.2 0.7 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.2 0.5 GO:0003796 lysozyme activity(GO:0003796)
0.1 0.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.4 GO:0003692 left-handed Z-DNA binding(GO:0003692)
0.1 2.3 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.4 GO:0004658 propionyl-CoA carboxylase activity(GO:0004658)
0.1 1.3 GO:0015250 water channel activity(GO:0015250)
0.1 0.7 GO:1904315 GABA-gated chloride ion channel activity(GO:0022851) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 0.6 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.1 0.8 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.7 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.3 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.2 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 1.0 GO:0044548 S100 protein binding(GO:0044548)
0.1 0.2 GO:0016901 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.1 0.2 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.1 0.2 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 0.3 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 0.2 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.1 0.2 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.1 0.4 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.4 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 1.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.2 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.1 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.2 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.1 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.3 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.2 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.2 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.2 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.2 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 1.6 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.1 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 0.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.2 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.4 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.1 GO:1903135 cupric ion binding(GO:1903135)
0.0 0.4 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.7 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.2 GO:0071253 connexin binding(GO:0071253)
0.0 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494) C-X-C chemokine binding(GO:0019958)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0 0.1 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.2 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.2 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.3 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.1 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.0 GO:0036361 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.0 0.0 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.0 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.0 0.2 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 9.3 GO:0003682 chromatin binding(GO:0003682)
0.0 0.3 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.1 GO:1990932 5.8S rRNA binding(GO:1990932)
0.0 0.2 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.0 0.1 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 0.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.2 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.3 GO:0008139 nuclear localization sequence binding(GO:0008139)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 10.6 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.1 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 1.2 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.0 0.8 ST_GA12_PATHWAY G alpha 12 Pathway
0.0 2.2 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 0.3 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.3 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 0.6 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 0.4 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.5 PID_NETRIN_PATHWAY Netrin-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.5 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.2 3.3 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.9 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 0.7 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.1 0.7 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 2.3 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 0.7 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.4 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.0 0.7 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.0 0.5 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.0 REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.6 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.3 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.7 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.3 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 2.5 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.4 REACTOME_PROCESSIVE_SYNTHESIS_ON_THE_LAGGING_STRAND Genes involved in Processive synthesis on the lagging strand
0.0 0.8 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.4 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.2 REACTOME_AMYLOIDS Genes involved in Amyloids
0.0 0.4 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.9 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.0 0.9 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.3 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.2 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.3 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.7 REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.6 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.2 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.4 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.3 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.2 REACTOME_IRON_UPTAKE_AND_TRANSPORT Genes involved in Iron uptake and transport
0.0 0.3 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions