Motif ID: Egr1

Z-value: 2.201


Transcription factors associated with Egr1:

Gene SymbolEntrez IDGene Name
Egr1 ENSMUSG00000038418.7 Egr1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Egr1mm10_v2_chr18_+_34861200_34861215-0.095.8e-01Click!


Activity profile for motif Egr1.

activity profile for motif Egr1


Sorted Z-values histogram for motif Egr1

Sorted Z-values for motif Egr1



Network of associatons between targets according to the STRING database.



First level regulatory network of Egr1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_6065538 24.893 ENSMUST00000101585.3
ENSMUST00000066431.7
ENSMUST00000109815.2
ENSMUST00000109812.2
ENSMUST00000101586.2
ENSMUST00000093355.5
ENSMUST00000019133.4
Camk2b






calcium/calmodulin-dependent protein kinase II, beta






chr14_-_33447142 12.424 ENSMUST00000111944.3
ENSMUST00000022504.5
ENSMUST00000111945.2
Mapk8


mitogen-activated protein kinase 8


chr5_-_139130159 10.303 ENSMUST00000129851.1
Prkar1b
protein kinase, cAMP dependent regulatory, type I beta
chr5_-_139129662 10.225 ENSMUST00000026973.7
Prkar1b
protein kinase, cAMP dependent regulatory, type I beta
chr11_+_98348404 9.227 ENSMUST00000078694.6
Ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr14_-_102982630 8.221 ENSMUST00000184744.1
KCTD12
mmu-mir-5130
chr7_+_73740277 7.937 ENSMUST00000107456.2
Fam174b
family with sequence similarity 174, member B
chr2_+_157914618 7.893 ENSMUST00000109523.1
Vstm2l
V-set and transmembrane domain containing 2-like
chr11_-_6065737 7.821 ENSMUST00000002817.5
ENSMUST00000109813.2
ENSMUST00000090443.3
Camk2b


calcium/calmodulin-dependent protein kinase II, beta


chr4_+_127169131 7.626 ENSMUST00000046659.7
Dlgap3
discs, large (Drosophila) homolog-associated protein 3
chr5_+_137553517 7.500 ENSMUST00000136088.1
ENSMUST00000139395.1
ENSMUST00000136565.1
ENSMUST00000149292.1
ENSMUST00000125489.1
Actl6b




actin-like 6B




chr7_-_27396542 7.323 ENSMUST00000108363.1
Sptbn4
spectrin beta, non-erythrocytic 4
chr7_+_82175156 7.125 ENSMUST00000180243.1
Sh3gl3
SH3-domain GRB2-like 3
chr7_+_82174796 6.841 ENSMUST00000032874.7
Sh3gl3
SH3-domain GRB2-like 3
chr5_+_137288273 6.822 ENSMUST00000024099.4
ENSMUST00000085934.3
Ache

acetylcholinesterase

chrX_-_20920911 6.606 ENSMUST00000081893.6
ENSMUST00000115345.1
Syn1

synapsin I

chr9_+_59750876 6.288 ENSMUST00000136740.1
ENSMUST00000135298.1
ENSMUST00000128341.1
Myo9a


myosin IXa


chr14_-_30353468 6.273 ENSMUST00000112249.1
Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr2_-_24763047 6.205 ENSMUST00000100348.3
ENSMUST00000041342.5
ENSMUST00000114447.1
ENSMUST00000102939.2
ENSMUST00000070864.7
Cacna1b




calcium channel, voltage-dependent, N type, alpha 1B subunit




chr4_-_22488296 6.178 ENSMUST00000178174.1
Pou3f2
POU domain, class 3, transcription factor 2
chr7_-_45370559 5.999 ENSMUST00000003971.7
Lin7b
lin-7 homolog B (C. elegans)
chr3_-_89089955 5.856 ENSMUST00000166687.1
Rusc1
RUN and SH3 domain containing 1
chr7_-_47132698 5.833 ENSMUST00000033142.5
Ptpn5
protein tyrosine phosphatase, non-receptor type 5
chr6_-_126645784 5.697 ENSMUST00000055168.3
Kcna1
potassium voltage-gated channel, shaker-related subfamily, member 1
chr3_+_28263205 5.685 ENSMUST00000159236.2
Tnik
TRAF2 and NCK interacting kinase
chr4_+_42917234 5.652 ENSMUST00000107976.2
ENSMUST00000069184.2
N28178

expressed sequence N28178

chr11_-_98053415 5.606 ENSMUST00000017544.2
Stac2
SH3 and cysteine rich domain 2
chrX_+_36195968 5.294 ENSMUST00000115256.1
Zcchc12
zinc finger, CCHC domain containing 12
chr6_-_60828889 5.004 ENSMUST00000114268.3
Snca
synuclein, alpha
chr5_-_62766153 4.900 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr8_+_84415348 4.880 ENSMUST00000121390.1
ENSMUST00000122053.1
Cacna1a

calcium channel, voltage-dependent, P/Q type, alpha 1A subunit

chr16_+_20589471 4.873 ENSMUST00000100074.3
ENSMUST00000096197.4
Vwa5b2

von Willebrand factor A domain containing 5B2

chr14_-_55585250 4.869 ENSMUST00000022828.8
Emc9
ER membrane protein complex subunit 9
chr10_-_116473418 4.733 ENSMUST00000087965.4
ENSMUST00000164271.1
Kcnmb4

potassium large conductance calcium-activated channel, subfamily M, beta member 4

chr11_+_119942763 4.732 ENSMUST00000026436.3
ENSMUST00000106231.1
ENSMUST00000075180.5
ENSMUST00000103021.3
ENSMUST00000106233.1
Baiap2




brain-specific angiogenesis inhibitor 1-associated protein 2




chr2_-_136387929 4.652 ENSMUST00000035264.2
ENSMUST00000077200.3
Pak7

p21 protein (Cdc42/Rac)-activated kinase 7

chr11_-_67922136 4.621 ENSMUST00000021288.3
ENSMUST00000108677.1
Usp43

ubiquitin specific peptidase 43

chr12_+_36157124 4.616 ENSMUST00000041640.3
Ankmy2
ankyrin repeat and MYND domain containing 2
chr13_-_54749627 4.608 ENSMUST00000099506.1
Gprin1
G protein-regulated inducer of neurite outgrowth 1
chr2_-_32312162 4.599 ENSMUST00000155269.1
Dnm1
dynamin 1
chr10_-_80139347 4.559 ENSMUST00000105369.1
Dos
downstream of Stk11
chr17_+_86167777 4.496 ENSMUST00000097275.2
Prkce
protein kinase C, epsilon
chr4_+_42949814 4.487 ENSMUST00000037872.3
ENSMUST00000098112.2
Dnajb5

DnaJ (Hsp40) homolog, subfamily B, member 5

chr19_-_4698315 4.479 ENSMUST00000096325.3
Gm960
predicted gene 960
chr18_+_32163073 4.396 ENSMUST00000096575.3
Map3k2
mitogen-activated protein kinase kinase kinase 2
chr2_+_145167706 4.352 ENSMUST00000110007.1
Slc24a3
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr8_+_104170513 4.348 ENSMUST00000171018.1
ENSMUST00000167633.1
ENSMUST00000093245.5
ENSMUST00000164076.1
Bean1



brain expressed, associated with Nedd4, 1



chr9_+_60712989 4.320 ENSMUST00000038407.5
Larp6
La ribonucleoprotein domain family, member 6
chr2_-_25319095 4.260 ENSMUST00000114318.3
ENSMUST00000114310.3
ENSMUST00000114308.3
ENSMUST00000114317.3
ENSMUST00000028335.6
ENSMUST00000114314.3
ENSMUST00000114307.1
Grin1






glutamate receptor, ionotropic, NMDA1 (zeta 1)






chr2_-_168741898 4.239 ENSMUST00000109176.1
ENSMUST00000178504.1
Atp9a

ATPase, class II, type 9A

chr4_+_124657646 4.236 ENSMUST00000053491.7
Pou3f1
POU domain, class 3, transcription factor 1
chr8_+_95678085 4.182 ENSMUST00000041318.7
Ndrg4
N-myc downstream regulated gene 4
chr3_+_28263563 4.164 ENSMUST00000160307.2
ENSMUST00000159680.2
ENSMUST00000160518.1
ENSMUST00000162485.1
ENSMUST00000159308.1
ENSMUST00000162777.1
ENSMUST00000161964.1
Tnik






TRAF2 and NCK interacting kinase






chr15_+_89499598 4.153 ENSMUST00000109309.1
Shank3
SH3/ankyrin domain gene 3
chr1_-_189343704 4.126 ENSMUST00000180044.1
ENSMUST00000110920.1
Kcnk2

potassium channel, subfamily K, member 2

chr10_-_127666673 4.066 ENSMUST00000026469.2
Nab2
Ngfi-A binding protein 2
chr5_+_137030275 4.028 ENSMUST00000041543.8
Vgf
VGF nerve growth factor inducible
chr7_-_109865586 4.024 ENSMUST00000007423.5
ENSMUST00000106728.2
ENSMUST00000106729.1
Scube2


signal peptide, CUB domain, EGF-like 2


chr12_+_78226627 3.956 ENSMUST00000110388.2
ENSMUST00000052472.4
Gphn

gephyrin

chr13_-_107890059 3.922 ENSMUST00000105097.2
Zswim6
zinc finger SWIM-type containing 6
chr4_-_151861762 3.876 ENSMUST00000097774.2
Camta1
calmodulin binding transcription activator 1
chr9_-_107710475 3.851 ENSMUST00000080560.3
Sema3f
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr10_-_127666598 3.848 ENSMUST00000099157.3
Nab2
Ngfi-A binding protein 2
chr19_-_5098418 3.823 ENSMUST00000025805.6
Cnih2
cornichon homolog 2 (Drosophila)
chr11_+_97415527 3.793 ENSMUST00000121799.1
Arhgap23
Rho GTPase activating protein 23
chrX_+_152144240 3.749 ENSMUST00000168786.1
ENSMUST00000112605.1
ENSMUST00000112604.1
Iqsec2


IQ motif and Sec7 domain 2


chr3_+_96596628 3.748 ENSMUST00000058943.7
Ankrd34a
ankyrin repeat domain 34A
chr4_-_149774238 3.740 ENSMUST00000105686.2
Slc25a33
solute carrier family 25, member 33
chr14_-_76556662 3.704 ENSMUST00000064517.7
Serp2
stress-associated endoplasmic reticulum protein family member 2
chr11_+_42419729 3.700 ENSMUST00000007797.4
Gabrb2
gamma-aminobutyric acid (GABA) A receptor, subunit beta 2
chr10_-_116473875 3.652 ENSMUST00000068233.4
Kcnmb4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr6_-_85502980 3.647 ENSMUST00000159062.1
Fbxo41
F-box protein 41
chr11_+_85832551 3.630 ENSMUST00000000095.6
Tbx2
T-box 2
chr13_-_54749849 3.620 ENSMUST00000135343.1
Gprin1
G protein-regulated inducer of neurite outgrowth 1
chr6_-_85502858 3.611 ENSMUST00000161546.1
ENSMUST00000161078.1
Fbxo41

F-box protein 41

chr10_-_81472859 3.591 ENSMUST00000147524.1
ENSMUST00000119060.1
Celf5

CUGBP, Elav-like family member 5

chr17_+_26715644 3.585 ENSMUST00000062519.7
ENSMUST00000144221.1
ENSMUST00000142539.1
ENSMUST00000151681.1
Crebrf



CREB3 regulatory factor



chrX_-_73660047 3.581 ENSMUST00000114472.1
Pnck
pregnancy upregulated non-ubiquitously expressed CaM kinase
chr7_+_99535652 3.541 ENSMUST00000032995.8
ENSMUST00000162404.1
Arrb1

arrestin, beta 1

chr12_+_102949450 3.538 ENSMUST00000179002.1
Unc79
unc-79 homolog (C. elegans)
chr7_+_126950837 3.523 ENSMUST00000106332.1
Sez6l2
seizure related 6 homolog like 2
chr12_+_71309876 3.489 ENSMUST00000061273.5
ENSMUST00000150639.1
Dact1

dapper homolog 1, antagonist of beta-catenin (xenopus)

chr1_-_56969864 3.466 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr16_+_44173271 3.460 ENSMUST00000088356.4
ENSMUST00000169582.1
Gm608

predicted gene 608

chrX_+_6047453 3.445 ENSMUST00000103007.3
Nudt11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr1_-_22805994 3.442 ENSMUST00000097808.4
Rims1
regulating synaptic membrane exocytosis 1
chr4_+_138250403 3.419 ENSMUST00000105818.1
ENSMUST00000105824.1
ENSMUST00000124239.1
Kif17
Sh2d5

kinesin family member 17
SH2 domain containing 5

chr9_-_112187766 3.386 ENSMUST00000111872.2
ENSMUST00000164754.2
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr7_+_5056856 3.372 ENSMUST00000131368.1
ENSMUST00000123956.1
Ccdc106

coiled-coil domain containing 106

chrX_+_36195938 3.345 ENSMUST00000048067.3
Zcchc12
zinc finger, CCHC domain containing 12
chr16_-_18629864 3.339 ENSMUST00000096987.5
Sept5
septin 5
chr1_-_189343342 3.308 ENSMUST00000079451.6
Kcnk2
potassium channel, subfamily K, member 2
chr7_+_40899278 3.305 ENSMUST00000044705.9
Vstm2b
V-set and transmembrane domain containing 2B
chr2_-_181135220 3.271 ENSMUST00000016491.7
Kcnq2
potassium voltage-gated channel, subfamily Q, member 2
chrX_-_47892396 3.264 ENSMUST00000153548.2
Smarca1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr10_+_79716588 3.249 ENSMUST00000099513.1
ENSMUST00000020581.2
Hcn2

hyperpolarization-activated, cyclic nucleotide-gated K+ 2

chr9_+_21165714 3.234 ENSMUST00000039413.8
Pde4a
phosphodiesterase 4A, cAMP specific
chrX_+_36195904 3.232 ENSMUST00000115258.2
Zcchc12
zinc finger, CCHC domain containing 12
chr11_-_108343917 3.228 ENSMUST00000059595.4
Prkca
protein kinase C, alpha
chr9_-_119093468 3.225 ENSMUST00000010804.2
Plcd1
phospholipase C, delta 1
chr4_-_151861698 3.222 ENSMUST00000049790.7
Camta1
calmodulin binding transcription activator 1
chrX_-_47892502 3.203 ENSMUST00000077569.4
ENSMUST00000101616.2
ENSMUST00000088973.4
Smarca1


SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1


chr12_+_102948843 3.201 ENSMUST00000101099.5
Unc79
unc-79 homolog (C. elegans)
chr4_+_136286061 3.188 ENSMUST00000069195.4
ENSMUST00000130658.1
Zfp46

zinc finger protein 46

chr2_+_143546144 3.177 ENSMUST00000028905.9
Pcsk2
proprotein convertase subtilisin/kexin type 2
chr9_-_112187898 3.176 ENSMUST00000178410.1
ENSMUST00000172380.3
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr3_-_89322883 3.173 ENSMUST00000029673.5
Efna3
ephrin A3
chr9_-_102354685 3.144 ENSMUST00000035129.7
ENSMUST00000085169.5
Ephb1

Eph receptor B1

chr11_+_75193783 3.108 ENSMUST00000102514.3
Rtn4rl1
reticulon 4 receptor-like 1
chr3_+_117575268 3.097 ENSMUST00000039564.6
4833424O15Rik
RIKEN cDNA 4833424O15 gene
chr3_+_54156039 3.091 ENSMUST00000029311.6
Trpc4
transient receptor potential cation channel, subfamily C, member 4
chr16_+_10545390 3.070 ENSMUST00000115827.1
ENSMUST00000038145.6
ENSMUST00000150894.1
Clec16a


C-type lectin domain family 16, member A


chr14_-_20546512 3.061 ENSMUST00000022355.4
ENSMUST00000161445.1
ENSMUST00000159027.1
Ppp3cb


protein phosphatase 3, catalytic subunit, beta isoform


chrX_+_36195950 3.056 ENSMUST00000115257.1
Zcchc12
zinc finger, CCHC domain containing 12
chr18_-_37935378 3.039 ENSMUST00000025337.7
Diap1
diaphanous homolog 1 (Drosophila)
chr8_-_73353477 3.014 ENSMUST00000119826.1
Large
like-glycosyltransferase
chr8_-_64205970 3.006 ENSMUST00000066166.4
Tll1
tolloid-like
chr7_-_45366714 2.981 ENSMUST00000107779.1
Ppfia3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr1_-_52233211 2.980 ENSMUST00000114513.2
ENSMUST00000114510.1
Gls

glutaminase

chr17_+_26414820 2.976 ENSMUST00000182897.1
ENSMUST00000183077.1
ENSMUST00000053020.7
Neurl1b


neuralized homolog 1b (Drosophila)


chr14_-_60177482 2.922 ENSMUST00000140924.1
Atp8a2
ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
chr7_+_122671401 2.910 ENSMUST00000182095.1
Cacng3
calcium channel, voltage-dependent, gamma subunit 3
chr16_+_94370786 2.906 ENSMUST00000147046.1
ENSMUST00000149885.1
ENSMUST00000127667.1
ENSMUST00000119131.1
ENSMUST00000145883.1
Ttc3




tetratricopeptide repeat domain 3




chr6_-_4747019 2.904 ENSMUST00000126151.1
ENSMUST00000133306.1
ENSMUST00000123907.1
Sgce


sarcoglycan, epsilon


chr1_-_56969827 2.900 ENSMUST00000176759.1
Satb2
special AT-rich sequence binding protein 2
chrX_-_47892432 2.898 ENSMUST00000141084.2
Smarca1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr16_+_44173239 2.873 ENSMUST00000119746.1
Gm608
predicted gene 608
chr16_+_94370618 2.855 ENSMUST00000117648.1
ENSMUST00000147352.1
ENSMUST00000150346.1
ENSMUST00000155692.1
ENSMUST00000153988.1
ENSMUST00000141856.1
ENSMUST00000152117.1
ENSMUST00000150097.1
ENSMUST00000122895.1
ENSMUST00000151770.1
Ttc3









tetratricopeptide repeat domain 3









chr16_+_20696175 2.855 ENSMUST00000128273.1
Fam131a
family with sequence similarity 131, member A
chr7_+_5057161 2.855 ENSMUST00000045543.5
Ccdc106
coiled-coil domain containing 106
chr9_-_51008936 2.842 ENSMUST00000176824.1
ENSMUST00000176663.1
ENSMUST00000041375.10
Sik2


salt inducible kinase 2


chr18_-_37935403 2.841 ENSMUST00000080033.6
ENSMUST00000115631.1
Diap1

diaphanous homolog 1 (Drosophila)

chr7_+_100227638 2.823 ENSMUST00000054436.8
Pgm2l1
phosphoglucomutase 2-like 1
chr19_+_42255704 2.805 ENSMUST00000087123.5
Golga7b
golgi autoantigen, golgin subfamily a, 7B
chrX_+_23693043 2.792 ENSMUST00000035766.6
ENSMUST00000101670.2
Wdr44

WD repeat domain 44

chr2_+_156613664 2.775 ENSMUST00000169464.2
ENSMUST00000109567.3
Dlgap4

discs, large homolog-associated protein 4 (Drosophila)

chr14_-_52279238 2.768 ENSMUST00000167116.1
ENSMUST00000100631.4
Rab2b

RAB2B, member RAS oncogene family

chr4_-_126753372 2.762 ENSMUST00000030637.7
ENSMUST00000106116.1
Ncdn

neurochondrin

chr16_-_20621255 2.756 ENSMUST00000052939.2
Camk2n2
calcium/calmodulin-dependent protein kinase II inhibitor 2
chr12_+_5375870 2.740 ENSMUST00000037953.6
2810032G03Rik
RIKEN cDNA 2810032G03 gene
chr8_+_88697022 2.714 ENSMUST00000043526.8
Cyld
cylindromatosis (turban tumor syndrome)
chr18_-_37935429 2.689 ENSMUST00000115634.1
Diap1
diaphanous homolog 1 (Drosophila)
chr7_+_80860909 2.683 ENSMUST00000132163.1
ENSMUST00000147125.1
Zscan2

zinc finger and SCAN domain containing 2

chr9_+_58582397 2.674 ENSMUST00000176557.1
ENSMUST00000114121.4
ENSMUST00000177064.1
Nptn


neuroplastin


chr9_-_54501496 2.668 ENSMUST00000118600.1
ENSMUST00000118163.1
Dmxl2

Dmx-like 2

chr3_-_89093358 2.664 ENSMUST00000090929.5
ENSMUST00000052539.6
Rusc1

RUN and SH3 domain containing 1

chr1_+_75382114 2.626 ENSMUST00000113590.1
ENSMUST00000148515.1
Speg

SPEG complex locus

chr14_+_101653967 2.622 ENSMUST00000002289.6
Uchl3
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr13_-_68999518 2.620 ENSMUST00000022013.7
Adcy2
adenylate cyclase 2
chr15_-_76660108 2.612 ENSMUST00000066677.8
ENSMUST00000177359.1
Cyhr1

cysteine and histidine rich 1

chr8_-_70234401 2.576 ENSMUST00000019679.5
Armc6
armadillo repeat containing 6
chr17_-_83631892 2.546 ENSMUST00000051482.1
Kcng3
potassium voltage-gated channel, subfamily G, member 3
chr15_-_45114926 2.542 ENSMUST00000022967.5
Kcnv1
potassium channel, subfamily V, member 1
chr3_+_136670679 2.528 ENSMUST00000056758.8
Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr16_-_4880284 2.515 ENSMUST00000037843.6
Ubald1
UBA-like domain containing 1
chr11_-_100759942 2.512 ENSMUST00000107363.2
Kcnh4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr12_-_76709997 2.480 ENSMUST00000166101.1
Sptb
spectrin beta, erythrocytic
chr8_-_122551316 2.476 ENSMUST00000067252.7
Piezo1
piezo-type mechanosensitive ion channel component 1
chr1_+_167001417 2.467 ENSMUST00000165874.1
Fam78b
family with sequence similarity 78, member B
chr4_+_42154040 2.444 ENSMUST00000108018.2
Gm13306
predicted gene 13306
chr11_-_78497458 2.442 ENSMUST00000108287.3
Sarm1
sterile alpha and HEAT/Armadillo motif containing 1
chr4_-_40722307 2.412 ENSMUST00000181475.1
Gm6297
predicted gene 6297
chr7_-_126704179 2.400 ENSMUST00000106364.1
Coro1a
coronin, actin binding protein 1A
chr19_+_27217357 2.394 ENSMUST00000047645.6
ENSMUST00000167487.1
Vldlr

very low density lipoprotein receptor

chr17_-_45686120 2.386 ENSMUST00000143907.1
ENSMUST00000127065.1
Tmem63b

transmembrane protein 63b

chr11_-_75796048 2.373 ENSMUST00000021209.7
Doc2b
double C2, beta
chr18_+_80256300 2.357 ENSMUST00000091798.3
ENSMUST00000140594.1
ENSMUST00000070135.7
Pqlc1


PQ loop repeat containing 1


chr2_-_25319187 2.355 ENSMUST00000114312.1
Grin1
glutamate receptor, ionotropic, NMDA1 (zeta 1)
chr9_-_107231816 2.352 ENSMUST00000044532.4
Dock3
dedicator of cyto-kinesis 3
chr8_-_70234097 2.347 ENSMUST00000130319.1
Armc6
armadillo repeat containing 6
chr2_-_118703963 2.341 ENSMUST00000104937.1
Ankrd63
ankyrin repeat domain 63
chr15_-_79834323 2.338 ENSMUST00000177316.2
ENSMUST00000175858.2
Nptxr

neuronal pentraxin receptor

chr8_-_124434323 2.333 ENSMUST00000140012.1
Pgbd5
piggyBac transposable element derived 5
chr7_+_122671378 2.323 ENSMUST00000182563.1
Cacng3
calcium channel, voltage-dependent, gamma subunit 3
chr2_+_52857844 2.317 ENSMUST00000090952.4
ENSMUST00000049483.6
ENSMUST00000050719.6
Fmnl2


formin-like 2


chr13_-_43304153 2.307 ENSMUST00000055341.5
Gfod1
glucose-fructose oxidoreductase domain containing 1
chr15_-_76243401 2.295 ENSMUST00000165738.1
ENSMUST00000075689.6
Parp10

poly (ADP-ribose) polymerase family, member 10

chr5_+_32136458 2.286 ENSMUST00000031017.9
Fosl2
fos-like antigen 2
chr11_-_100759740 2.263 ENSMUST00000107361.2
Kcnh4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr19_-_5085483 2.258 ENSMUST00000140389.1
ENSMUST00000151413.1
ENSMUST00000077066.7
Tmem151a


transmembrane protein 151A


chr4_-_41774097 2.254 ENSMUST00000108036.1
ENSMUST00000173865.1
ENSMUST00000108037.2
ENSMUST00000108032.2
Ccl27a



chemokine (C-C motif) ligand 27A



chr13_+_100108155 2.243 ENSMUST00000129014.1
Serf1
small EDRK-rich factor 1
chr1_+_42952872 2.239 ENSMUST00000179766.1
Gpr45
G protein-coupled receptor 45
chr9_+_21032038 2.236 ENSMUST00000019616.4
Icam5
intercellular adhesion molecule 5, telencephalin
chr3_+_106721893 2.235 ENSMUST00000106736.2
ENSMUST00000154973.1
ENSMUST00000131330.1
ENSMUST00000150513.1
Lrif1



ligand dependent nuclear receptor interacting factor 1



chr7_+_100227311 2.227 ENSMUST00000084935.3
Pgm2l1
phosphoglucomutase 2-like 1
chr15_-_79742493 2.221 ENSMUST00000100439.3
Sun2
Sad1 and UNC84 domain containing 2
chr5_+_30588078 2.213 ENSMUST00000066295.2
Kcnk3
potassium channel, subfamily K, member 3
chr9_-_24503127 2.201 ENSMUST00000142064.1
ENSMUST00000170356.1
Dpy19l1

dpy-19-like 1 (C. elegans)

chr13_-_96132568 2.195 ENSMUST00000161263.1
Sv2c
synaptic vesicle glycoprotein 2c
chr18_+_64887690 2.161 ENSMUST00000163516.1
Nedd4l
neural precursor cell expressed, developmentally down-regulated gene 4-like
chr17_-_45685973 2.139 ENSMUST00000145873.1
Tmem63b
transmembrane protein 63b
chr7_+_101108768 2.138 ENSMUST00000098250.3
ENSMUST00000032931.7
Fchsd2

FCH and double SH3 domains 2

chr13_+_100107997 2.133 ENSMUST00000142155.1
ENSMUST00000022145.8
ENSMUST00000132053.1
Serf1


small EDRK-rich factor 1


chrX_-_20291776 2.118 ENSMUST00000072451.4
Slc9a7
solute carrier family 9 (sodium/hydrogen exchanger), member 7
chr3_+_106721672 2.112 ENSMUST00000098750.2
ENSMUST00000130105.1
Lrif1

ligand dependent nuclear receptor interacting factor 1

chr11_+_97799772 2.108 ENSMUST00000129558.1
Lasp1
LIM and SH3 protein 1
chr5_-_77408034 2.101 ENSMUST00000163898.1
ENSMUST00000046746.6
Igfbp7

insulin-like growth factor binding protein 7

chr18_+_80256249 2.075 ENSMUST00000129043.1
Pqlc1
PQ loop repeat containing 1
chr11_-_72135721 2.073 ENSMUST00000108508.2
ENSMUST00000075258.6
Pitpnm3

PITPNM family member 3


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
10.9 32.7 GO:0032430 inhibitory G-protein coupled receptor phosphorylation(GO:0002030) positive regulation of phospholipase A2 activity(GO:0032430) activation of meiosis involved in egg activation(GO:0060466)
3.1 12.4 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
3.1 9.2 GO:0007621 negative regulation of female receptivity(GO:0007621)
3.0 14.9 GO:2000325 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
2.5 5.0 GO:0045963 negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963)
2.5 7.4 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
2.2 6.6 GO:1900673 olefin metabolic process(GO:1900673)
2.1 10.5 GO:0007256 activation of JNKK activity(GO:0007256)
1.9 5.7 GO:0050975 sensory perception of touch(GO:0050975)
1.7 20.6 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
1.6 4.9 GO:0050883 regulation of sulfur amino acid metabolic process(GO:0031335) musculoskeletal movement, spinal reflex action(GO:0050883)
1.3 6.5 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
1.3 6.3 GO:2001025 positive regulation of response to drug(GO:2001025)
1.2 7.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
1.2 3.6 GO:0007521 muscle cell fate determination(GO:0007521) mammary placode formation(GO:0060596)
1.2 15.7 GO:0016191 synaptic vesicle uncoating(GO:0016191)
1.2 6.0 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
1.1 6.8 GO:0019695 choline metabolic process(GO:0019695)
1.1 6.8 GO:0032796 uropod organization(GO:0032796)
1.1 7.9 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
1.1 4.5 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
1.1 4.5 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
1.1 8.9 GO:0005513 detection of calcium ion(GO:0005513)
1.1 3.2 GO:0002159 desmosome assembly(GO:0002159)
1.1 3.2 GO:0030070 insulin processing(GO:0030070)
1.0 4.9 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
1.0 4.9 GO:0006543 glutamine catabolic process(GO:0006543)
0.9 3.7 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.9 3.4 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.9 4.3 GO:0034436 glycoprotein transport(GO:0034436)
0.8 2.5 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) regulation of connective tissue replacement(GO:1905203)
0.8 4.2 GO:0090292 nuclear migration along microfilament(GO:0031022) nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.8 4.2 GO:1904717 positive regulation of synapse structural plasticity(GO:0051835) regulation of AMPA glutamate receptor clustering(GO:1904717)
0.8 2.5 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.8 0.8 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.8 4.0 GO:1902732 positive regulation of chondrocyte proliferation(GO:1902732)
0.8 4.0 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.8 2.3 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.8 2.3 GO:0071677 positive regulation of mononuclear cell migration(GO:0071677)
0.7 3.0 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.7 2.2 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.7 2.2 GO:0072720 response to sorbitol(GO:0072708) response to dithiothreitol(GO:0072720)
0.7 0.7 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.7 6.7 GO:0048149 behavioral response to ethanol(GO:0048149)
0.7 3.3 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.7 4.6 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.7 3.3 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.6 3.2 GO:0070305 response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321)
0.6 3.9 GO:0097491 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.6 3.2 GO:1905247 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.6 3.1 GO:2001015 negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.6 9.6 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.6 3.4 GO:1901911 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.6 1.7 GO:0002447 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
0.6 3.4 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.5 1.1 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.5 2.7 GO:0097343 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.5 2.0 GO:1990034 calcium ion export from cell(GO:1990034)
0.5 1.0 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.5 1.9 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.5 4.4 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.5 6.2 GO:0001956 positive regulation of neurotransmitter secretion(GO:0001956)
0.4 3.1 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.4 1.8 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.4 2.2 GO:0060437 lung growth(GO:0060437)
0.4 2.2 GO:2001286 regulation of caveolin-mediated endocytosis(GO:2001286)
0.4 3.9 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.4 6.4 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.4 2.9 GO:0061092 involuntary skeletal muscle contraction(GO:0003011) regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.4 3.7 GO:0071420 cellular response to histamine(GO:0071420)
0.4 4.4 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.4 1.2 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.4 0.8 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.4 1.6 GO:0050913 sensory perception of bitter taste(GO:0050913)
0.4 3.5 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.4 3.1 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.4 1.8 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.4 4.0 GO:0043084 penile erection(GO:0043084)
0.4 1.8 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.3 0.3 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.3 2.0 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.3 5.3 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.3 4.2 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.3 1.9 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.3 0.9 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.3 2.7 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.3 0.9 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.3 2.1 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.3 1.2 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.3 3.7 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.3 1.4 GO:0015871 choline transport(GO:0015871) negative regulation of RIG-I signaling pathway(GO:0039536)
0.3 4.7 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.3 2.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.3 1.7 GO:0097264 self proteolysis(GO:0097264)
0.3 5.2 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.3 1.6 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.3 0.8 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.3 2.9 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.3 1.3 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.3 3.1 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.3 3.6 GO:1900102 negative regulation of endoplasmic reticulum unfolded protein response(GO:1900102)
0.3 1.5 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.2 4.5 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.2 1.2 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.2 1.2 GO:1901660 calcium ion export(GO:1901660)
0.2 1.9 GO:0061368 maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.2 1.2 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.2 0.7 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.2 1.9 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.2 1.6 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.2 1.3 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.2 2.6 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.2 1.3 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.2 2.4 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.2 4.0 GO:0030033 microvillus assembly(GO:0030033)
0.2 1.1 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.2 1.6 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.2 4.3 GO:0006491 N-glycan processing(GO:0006491)
0.2 0.8 GO:0030576 Cajal body organization(GO:0030576)
0.2 5.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.2 1.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.2 1.3 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.2 1.3 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.2 0.7 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.2 5.0 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.2 1.6 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.2 0.7 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.2 2.4 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
0.2 1.7 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.2 1.4 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.2 0.3 GO:0099527 postsynapse to nucleus signaling pathway(GO:0099527)
0.2 3.5 GO:0060074 synapse maturation(GO:0060074)
0.2 1.7 GO:0016926 protein desumoylation(GO:0016926)
0.2 5.6 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.2 0.9 GO:0070314 G1 to G0 transition(GO:0070314)
0.2 0.9 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 1.2 GO:0097623 potassium ion export across plasma membrane(GO:0097623)
0.1 0.3 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.1 1.9 GO:0060259 regulation of feeding behavior(GO:0060259)
0.1 0.9 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.1 1.3 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.1 1.5 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.1 5.1 GO:2001222 regulation of neuron migration(GO:2001222)
0.1 6.8 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.1 3.9 GO:0061157 mRNA destabilization(GO:0061157)
0.1 1.1 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.1 0.8 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 1.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.8 GO:0030578 PML body organization(GO:0030578)
0.1 2.8 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.1 0.5 GO:0001771 immunological synapse formation(GO:0001771)
0.1 4.5 GO:0009311 oligosaccharide metabolic process(GO:0009311)
0.1 1.1 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.1 1.3 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.4 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1 0.3 GO:0035793 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512) cell migration involved in metanephros development(GO:0035788) metanephric mesenchymal cell migration(GO:0035789) positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) regulation of metanephric mesenchymal cell migration(GO:2000589) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.1 0.7 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.8 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.6 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.1 0.4 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.1 1.3 GO:0072643 interferon-gamma secretion(GO:0072643)
0.1 0.8 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.1 2.6 GO:0042755 eating behavior(GO:0042755)
0.1 2.5 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.1 0.8 GO:1900116 sequestering of extracellular ligand from receptor(GO:0035581) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 0.2 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.1 4.6 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 3.7 GO:0034605 cellular response to heat(GO:0034605)
0.1 3.1 GO:1902186 regulation of viral release from host cell(GO:1902186)
0.1 1.6 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1 2.4 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 5.0 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.1 0.7 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.1 0.6 GO:0071285 cellular response to lithium ion(GO:0071285)
0.1 1.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 6.5 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.1 1.3 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.1 1.1 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.1 0.3 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.1 1.8 GO:0021859 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.1 3.8 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.1 0.8 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 0.5 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.1 1.6 GO:0046326 positive regulation of glucose import(GO:0046326)
0.1 15.6 GO:0000209 protein polyubiquitination(GO:0000209)
0.1 0.3 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.9 GO:0030011 maintenance of cell polarity(GO:0030011)
0.1 2.3 GO:0032355 response to estradiol(GO:0032355)
0.1 0.5 GO:0048793 pronephros development(GO:0048793)
0.1 0.3 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.8 GO:0006817 phosphate ion transport(GO:0006817)
0.1 2.0 GO:0014037 Schwann cell differentiation(GO:0014037)
0.1 0.2 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 1.9 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.1 2.5 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.1 2.0 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.1 10.0 GO:0006813 potassium ion transport(GO:0006813)
0.1 1.1 GO:0007616 long-term memory(GO:0007616)
0.1 1.5 GO:0008333 endosome to lysosome transport(GO:0008333)
0.1 0.7 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1 0.2 GO:0006106 fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533) alditol biosynthetic process(GO:0019401)
0.1 5.2 GO:2001237 negative regulation of extrinsic apoptotic signaling pathway(GO:2001237)
0.1 2.7 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626)
0.1 0.4 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.1 0.7 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 0.4 GO:0045056 transcytosis(GO:0045056)
0.1 2.1 GO:0048839 inner ear development(GO:0048839)
0.1 1.1 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.1 0.5 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.1 6.9 GO:0043524 negative regulation of neuron apoptotic process(GO:0043524)
0.1 1.0 GO:0044804 nucleophagy(GO:0044804)
0.1 0.1 GO:0071455 response to hyperoxia(GO:0055093) cellular response to hyperoxia(GO:0071455)
0.0 0.8 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 0.5 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.0 0.5 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.5 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.4 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 7.1 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 1.2 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.2 GO:0032511 endosome transport via multivesicular body sorting pathway(GO:0032509) late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 1.1 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.1 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.2 GO:0015862 uridine transport(GO:0015862)
0.0 3.0 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.5 GO:1901798 positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0 2.2 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 2.2 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 1.9 GO:0008589 regulation of smoothened signaling pathway(GO:0008589)
0.0 1.2 GO:0042770 signal transduction in response to DNA damage(GO:0042770)
0.0 3.4 GO:0006457 protein folding(GO:0006457)
0.0 0.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.6 GO:0016239 positive regulation of macroautophagy(GO:0016239)
0.0 1.7 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 0.5 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.0 3.4 GO:0031098 stress-activated protein kinase signaling cascade(GO:0031098)
0.0 1.3 GO:0006165 nucleoside diphosphate phosphorylation(GO:0006165)
0.0 0.2 GO:0009408 response to heat(GO:0009408)
0.0 0.1 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.7 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 1.4 GO:0030833 regulation of actin filament polymerization(GO:0030833)
0.0 0.2 GO:0010452 histone H3-K36 methylation(GO:0010452)
0.0 0.1 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.0 0.4 GO:0002011 morphogenesis of an epithelial sheet(GO:0002011)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 9.4 GO:0090537 CERF complex(GO:0090537)
1.7 6.6 GO:0044307 dendritic branch(GO:0044307)
1.6 21.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
1.6 9.8 GO:0008091 spectrin(GO:0008091)
1.3 7.7 GO:0005955 calcineurin complex(GO:0005955)
1.3 5.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
1.2 7.4 GO:0044305 calyx of Held(GO:0044305)
1.2 4.9 GO:0016012 sarcoglycan complex(GO:0016012)
1.1 3.4 GO:1990075 periciliary membrane compartment(GO:1990075)
1.1 3.3 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
1.1 3.2 GO:0098855 HCN channel complex(GO:0098855)
0.9 31.9 GO:0051233 spindle midzone(GO:0051233)
0.9 3.4 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.9 6.0 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.7 6.8 GO:0032426 stereocilium tip(GO:0032426)
0.6 6.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.6 7.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.5 4.3 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.5 4.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.5 6.8 GO:0043083 synaptic cleft(GO:0043083)
0.5 7.9 GO:1990635 proximal dendrite(GO:1990635)
0.4 1.3 GO:0044194 cytolytic granule(GO:0044194)
0.4 1.7 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.4 4.3 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.3 11.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.3 5.4 GO:0043196 varicosity(GO:0043196)
0.3 4.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.3 5.7 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.3 6.0 GO:0016514 SWI/SNF complex(GO:0016514)
0.3 5.0 GO:0034704 calcium channel complex(GO:0034704)
0.3 1.2 GO:0043293 apoptosome(GO:0043293)
0.3 2.9 GO:0071141 SMAD protein complex(GO:0071141)
0.3 9.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.3 2.0 GO:0032591 dendritic spine membrane(GO:0032591)
0.3 2.5 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.3 18.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.3 1.4 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.3 11.6 GO:0002102 podosome(GO:0002102)
0.3 10.4 GO:0048786 presynaptic active zone(GO:0048786)
0.3 0.8 GO:1903095 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.2 3.7 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.2 2.8 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.2 1.4 GO:0072687 meiotic spindle(GO:0072687)
0.2 3.1 GO:0032433 filopodium tip(GO:0032433)
0.2 3.3 GO:0031105 septin complex(GO:0031105)
0.2 0.4 GO:0032839 dendrite cytoplasm(GO:0032839)
0.2 3.5 GO:0031143 pseudopodium(GO:0031143)
0.2 1.5 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.2 1.5 GO:0070695 FHF complex(GO:0070695)
0.2 1.1 GO:0031523 Myb complex(GO:0031523)
0.2 1.1 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.2 2.7 GO:0097542 ciliary tip(GO:0097542)
0.2 3.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 4.0 GO:0060077 inhibitory synapse(GO:0060077)
0.2 1.6 GO:0044294 dendritic growth cone(GO:0044294)
0.2 0.6 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.2 0.7 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.2 5.9 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 2.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 1.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 1.2 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.1 0.9 GO:0044327 dendritic spine head(GO:0044327)
0.1 1.7 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.1 1.7 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 0.9 GO:0033263 CORVET complex(GO:0033263)
0.1 13.8 GO:0055037 recycling endosome(GO:0055037)
0.1 0.7 GO:0030125 clathrin vesicle coat(GO:0030125)
0.1 0.3 GO:0098830 presynaptic endosome(GO:0098830)
0.1 1.2 GO:0000812 Swr1 complex(GO:0000812)
0.1 5.3 GO:0016459 myosin complex(GO:0016459)
0.1 2.0 GO:0060170 ciliary membrane(GO:0060170)
0.1 20.0 GO:0005769 early endosome(GO:0005769)
0.1 3.5 GO:0032420 stereocilium(GO:0032420)
0.1 1.9 GO:0071004 U2-type prespliceosome(GO:0071004)
0.1 1.7 GO:0000145 exocyst(GO:0000145)
0.1 1.8 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 1.1 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.1 1.3 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 3.5 GO:0030139 endocytic vesicle(GO:0030139)
0.1 2.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 1.0 GO:0010369 chromocenter(GO:0010369)
0.1 2.4 GO:0031201 SNARE complex(GO:0031201)
0.1 1.1 GO:0042555 MCM complex(GO:0042555)
0.1 0.7 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 0.7 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 3.2 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 2.3 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 4.9 GO:0010008 endosome membrane(GO:0010008)
0.1 0.7 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 15.8 GO:0000139 Golgi membrane(GO:0000139)
0.1 0.8 GO:0017119 Golgi transport complex(GO:0017119)
0.1 1.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.7 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.3 GO:0098858 actin-based cell projection(GO:0098858)
0.0 2.8 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 2.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.0 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.5 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 1.4 GO:0043679 axon terminus(GO:0043679)
0.0 1.5 GO:0030175 filopodium(GO:0030175)
0.0 1.2 GO:0016235 aggresome(GO:0016235)
0.0 1.3 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 5.6 GO:0031253 cell projection membrane(GO:0031253)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 1.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.0 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 3.2 GO:0008021 synaptic vesicle(GO:0008021)
0.0 2.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.7 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.6 GO:0005871 kinesin complex(GO:0005871)
0.0 1.0 GO:0005795 Golgi stack(GO:0005795)
0.0 1.9 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0031209 SCAR complex(GO:0031209)
0.0 9.6 GO:0005773 vacuole(GO:0005773)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 6.0 GO:0005667 transcription factor complex(GO:0005667)
0.0 6.2 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.4 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.7 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.3 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.8 GO:0005643 nuclear pore(GO:0005643)
0.0 0.4 GO:0045171 intercellular bridge(GO:0045171)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 9.4 GO:0070615 nucleosome-dependent ATPase activity(GO:0070615)
3.1 12.4 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
3.1 9.2 GO:0031752 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
1.9 20.5 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
1.7 6.8 GO:0004104 cholinesterase activity(GO:0004104) choline binding(GO:0033265)
1.5 38.1 GO:0043274 phospholipase binding(GO:0043274)
1.4 4.3 GO:0034437 very-low-density lipoprotein particle binding(GO:0034189) glycoprotein transporter activity(GO:0034437)
1.2 17.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
1.2 4.8 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
1.2 3.5 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
1.1 4.5 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
1.1 6.6 GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
1.1 3.2 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
1.0 4.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
1.0 4.0 GO:0097108 hedgehog family protein binding(GO:0097108)
1.0 6.0 GO:0097016 L27 domain binding(GO:0097016)
1.0 4.0 GO:0043546 molybdopterin cofactor binding(GO:0043546)
1.0 4.9 GO:0004359 glutaminase activity(GO:0004359)
1.0 2.9 GO:0035500 MH2 domain binding(GO:0035500)
1.0 9.6 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.9 5.6 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.9 3.7 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.9 4.4 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.8 2.5 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.8 3.2 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.7 5.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.7 9.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.7 2.0 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.6 1.9 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.6 6.8 GO:0032036 myosin heavy chain binding(GO:0032036)
0.6 1.2 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.6 4.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.6 2.3 GO:0001847 opsonin receptor activity(GO:0001847)
0.6 4.6 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.6 3.4 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.6 2.8 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.5 8.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.5 6.3 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.5 1.4 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.5 8.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.4 1.3 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.4 1.3 GO:0004686 elongation factor-2 kinase activity(GO:0004686)
0.4 2.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.4 4.3 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.4 3.1 GO:0015386 potassium:proton antiporter activity(GO:0015386) potassium ion antiporter activity(GO:0022821)
0.4 4.2 GO:0043495 protein anchor(GO:0043495)
0.4 2.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.3 3.1 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.3 2.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.3 1.7 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.3 3.7 GO:0004016 adenylate cyclase activity(GO:0004016)
0.3 1.5 GO:0042610 CD8 receptor binding(GO:0042610)
0.3 8.8 GO:0032183 SUMO binding(GO:0032183)
0.3 5.7 GO:0070300 phosphatidic acid binding(GO:0070300)
0.3 1.2 GO:2001069 glycogen binding(GO:2001069)
0.3 3.9 GO:0038191 neuropilin binding(GO:0038191)
0.3 3.5 GO:0070097 delta-catenin binding(GO:0070097)
0.3 7.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.3 1.1 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.3 1.6 GO:0097001 ceramide binding(GO:0097001)
0.3 1.8 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.3 1.8 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.2 1.7 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.2 2.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.2 0.7 GO:0019002 GMP binding(GO:0019002)
0.2 0.9 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.2 1.4 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.2 3.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.2 1.1 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.2 4.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.2 5.2 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.2 0.8 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.2 4.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.2 1.2 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.2 8.6 GO:0001784 phosphotyrosine binding(GO:0001784)
0.2 1.7 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.2 4.4 GO:0015605 organophosphate ester transmembrane transporter activity(GO:0015605)
0.2 2.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 0.8 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1 7.3 GO:0030507 spectrin binding(GO:0030507)
0.1 3.2 GO:0030552 cAMP binding(GO:0030552)
0.1 6.3 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.1 3.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 1.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 5.6 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 0.5 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.1 1.2 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 2.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 1.3 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 1.1 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.1 1.4 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 1.8 GO:0008373 sialyltransferase activity(GO:0008373)
0.1 8.8 GO:0051219 phosphoprotein binding(GO:0051219)
0.1 2.2 GO:0000030 mannosyltransferase activity(GO:0000030)
0.1 2.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 2.3 GO:0031489 myosin V binding(GO:0031489)
0.1 0.5 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 5.9 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 3.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 2.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 2.8 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 1.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 2.1 GO:0070064 proline-rich region binding(GO:0070064)
0.1 9.3 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1 0.8 GO:0036122 BMP binding(GO:0036122)
0.1 1.1 GO:0005522 profilin binding(GO:0005522)
0.1 0.7 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 2.0 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.5 GO:0051425 PTB domain binding(GO:0051425)
0.1 0.9 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 2.1 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 6.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 1.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 1.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 4.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 4.4 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.1 1.5 GO:0015026 coreceptor activity(GO:0015026)
0.1 3.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.6 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.3 GO:0070012 oligopeptidase activity(GO:0070012)
0.1 3.9 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 0.8 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.1 1.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 1.9 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 1.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 2.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 5.6 GO:0003774 motor activity(GO:0003774)
0.1 0.2 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 1.7 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 0.2 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.1 8.7 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 0.5 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 1.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.6 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013)
0.1 2.3 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 1.7 GO:0005112 Notch binding(GO:0005112)
0.1 1.3 GO:0017046 peptide hormone binding(GO:0017046)
0.1 1.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 4.8 GO:0051087 chaperone binding(GO:0051087)
0.1 3.1 GO:0004620 phospholipase activity(GO:0004620)
0.0 1.8 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 1.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.9 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.6 GO:0070403 NAD+ binding(GO:0070403)
0.0 1.1 GO:0071617 lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.3 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 1.5 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 3.8 GO:0016247 channel regulator activity(GO:0016247)
0.0 1.7 GO:0019905 syntaxin binding(GO:0019905)
0.0 18.8 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 3.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 6.3 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.9 GO:0016504 peptidase activator activity(GO:0016504)
0.0 5.4 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 2.5 GO:0005496 steroid binding(GO:0005496)
0.0 0.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 1.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 4.5 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.3 GO:1901981 phosphatidylinositol phosphate binding(GO:1901981)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.9 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 6.0 GO:0045296 cadherin binding(GO:0045296)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.2 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 29.4 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.9 12.3 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.5 9.0 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.4 17.6 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.4 11.6 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.3 13.3 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.3 7.7 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.2 7.2 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.2 24.5 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.2 4.3 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2 4.6 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.2 5.6 PID_ARF6_PATHWAY Arf6 signaling events
0.1 2.2 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.1 4.4 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.1 3.1 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.1 5.6 PID_RAC1_PATHWAY RAC1 signaling pathway
0.1 1.9 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.1 4.2 PID_CD8_TCR_PATHWAY TCR signaling in naïve CD8+ T cells
0.1 5.7 PID_LKB1_PATHWAY LKB1 signaling events
0.1 1.1 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.1 2.0 PID_PI3KCI_AKT_PATHWAY Class I PI3K signaling events mediated by Akt
0.1 1.9 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.1 1.7 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.1 1.7 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 1.7 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.1 2.8 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.1 0.6 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 2.2 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 1.9 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.1 1.6 PID_CDC42_PATHWAY CDC42 signaling events
0.0 2.1 PID_P73PATHWAY p73 transcription factor network
0.0 1.1 PID_IL12_2PATHWAY IL12-mediated signaling events
0.0 0.5 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 4.9 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.5 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 1.9 PID_CMYB_PATHWAY C-MYB transcription factor network
0.0 0.8 PID_ERBB4_PATHWAY ErbB4 signaling events
0.0 0.7 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.5 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 0.6 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.5 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 0.4 PID_ARF_3PATHWAY Arf1 pathway
0.0 0.6 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 1.7 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.4 PID_FOXO_PATHWAY FoxO family signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 39.3 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
1.4 9.6 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
1.1 25.0 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.8 11.8 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.8 11.6 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.6 3.1 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.6 16.4 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.5 10.1 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.5 8.2 REACTOME_DAG_AND_IP3_SIGNALING Genes involved in DAG and IP3 signaling
0.4 4.9 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.4 18.4 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.3 4.7 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.3 5.7 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.3 6.8 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.3 2.7 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 4.9 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.2 3.7 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.2 8.4 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.2 6.1 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS Genes involved in Trafficking of AMPA receptors
0.2 2.2 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.2 2.9 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.2 2.7 REACTOME_NOD1_2_SIGNALING_PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.2 1.8 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 1.7 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 4.0 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 1.9 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 1.1 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.1 REACTOME_ACYL_CHAIN_REMODELLING_OF_PI Genes involved in Acyl chain remodelling of PI
0.1 9.8 REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH Genes involved in NCAM signaling for neurite out-growth
0.1 2.0 REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 1.3 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.1 2.5 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.1 1.4 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 2.8 REACTOME_DOWNSTREAM_TCR_SIGNALING Genes involved in Downstream TCR signaling
0.1 8.6 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 2.5 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 1.2 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.1 0.4 REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS Genes involved in Prolonged ERK activation events
0.1 0.5 REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1 0.5 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 1.7 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 1.8 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 1.9 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 0.8 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.1 1.3 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.4 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.6 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 8.1 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.9 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.7 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 2.6 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.1 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.7 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.4 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.2 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 3.0 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.4 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.6 REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 0.7 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.6 REACTOME_AMYLOIDS Genes involved in Amyloids
0.0 0.8 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.5 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.5 REACTOME_REGULATION_OF_INSULIN_SECRETION Genes involved in Regulation of Insulin Secretion
0.0 0.7 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.0 0.5 REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION Genes involved in Downstream signal transduction