Motif ID: Zfp219_Zfp740

Z-value: 1.274

Transcription factors associated with Zfp219_Zfp740:

Gene SymbolEntrez IDGene Name
Zfp219 ENSMUSG00000049295.10 Zfp219
Zfp740 ENSMUSG00000046897.10 Zfp740

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp740mm10_v2_chr15_+_102203639_1022037090.417.7e-03Click!
Zfp219mm10_v2_chr14_-_52020698_520207370.408.9e-03Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp219_Zfp740

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_134747241 7.731 ENSMUST00000015138.9
Eln
elastin
chr1_-_56972437 7.474 ENSMUST00000042857.7
Satb2
special AT-rich sequence binding protein 2
chr7_-_78577771 7.471 ENSMUST00000039438.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr7_-_78578308 6.847 ENSMUST00000039431.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr10_-_127341583 6.405 ENSMUST00000026474.3
Gli1
GLI-Kruppel family member GLI1
chr15_+_57694651 5.930 ENSMUST00000096430.4
Zhx2
zinc fingers and homeoboxes 2
chr10_-_127620922 5.839 ENSMUST00000118455.1
Lrp1
low density lipoprotein receptor-related protein 1
chr11_-_69369377 5.705 ENSMUST00000092971.6
ENSMUST00000108661.1
Chd3

chromodomain helicase DNA binding protein 3

chr10_-_127620960 4.999 ENSMUST00000121829.1
Lrp1
low density lipoprotein receptor-related protein 1
chr16_+_44173271 4.912 ENSMUST00000088356.4
ENSMUST00000169582.1
Gm608

predicted gene 608

chr2_-_36105271 4.859 ENSMUST00000112960.1
ENSMUST00000112967.5
ENSMUST00000112963.1
Lhx6


LIM homeobox protein 6


chr16_+_43503607 4.779 ENSMUST00000126100.1
ENSMUST00000123047.1
ENSMUST00000156981.1
Zbtb20


zinc finger and BTB domain containing 20


chr7_+_127511976 4.750 ENSMUST00000098025.4
Srcap
Snf2-related CREBBP activator protein
chr3_+_28263563 4.741 ENSMUST00000160307.2
ENSMUST00000159680.2
ENSMUST00000160518.1
ENSMUST00000162485.1
ENSMUST00000159308.1
ENSMUST00000162777.1
ENSMUST00000161964.1
Tnik






TRAF2 and NCK interacting kinase






chr19_-_59170978 4.589 ENSMUST00000172821.2
Vax1
ventral anterior homeobox containing gene 1
chr7_+_127777095 4.569 ENSMUST00000144406.1
Setd1a
SET domain containing 1A
chr2_+_48949495 3.929 ENSMUST00000112745.1
Mbd5
methyl-CpG binding domain protein 5
chr2_-_116065798 3.886 ENSMUST00000110907.1
ENSMUST00000110908.2
Meis2

Meis homeobox 2

chr1_-_168431695 3.686 ENSMUST00000176790.1
Pbx1
pre B cell leukemia homeobox 1
chr6_+_4903350 3.685 ENSMUST00000175962.1
Ppp1r9a
protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr2_-_180225812 3.572 ENSMUST00000015791.5
Lama5
laminin, alpha 5
chr2_-_31141802 3.510 ENSMUST00000073879.5
ENSMUST00000100208.2
ENSMUST00000100207.2
ENSMUST00000113555.1
ENSMUST00000075326.4
ENSMUST00000113552.2
ENSMUST00000136181.1
Fnbp1






formin binding protein 1






chr9_-_44881274 3.438 ENSMUST00000002095.3
ENSMUST00000114689.1
ENSMUST00000128768.1
Kmt2a


lysine (K)-specific methyltransferase 2A


chr17_+_75005523 3.376 ENSMUST00000001927.5
Ltbp1
latent transforming growth factor beta binding protein 1
chr4_+_144892813 3.287 ENSMUST00000105744.1
ENSMUST00000171001.1
Dhrs3

dehydrogenase/reductase (SDR family) member 3

chrX_-_94123087 3.270 ENSMUST00000113925.1
Zfx
zinc finger protein X-linked
chr16_+_44173239 3.268 ENSMUST00000119746.1
Gm608
predicted gene 608
chr12_-_27342696 3.164 ENSMUST00000079063.5
Sox11
SRY-box containing gene 11
chr11_+_69765970 2.964 ENSMUST00000108642.1
ENSMUST00000156932.1
Zbtb4

zinc finger and BTB domain containing 4

chr4_-_88033328 2.951 ENSMUST00000078090.5
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr1_-_64121389 2.918 ENSMUST00000055001.3
Klf7
Kruppel-like factor 7 (ubiquitous)
chr9_+_44499126 2.846 ENSMUST00000074989.5
Bcl9l
B cell CLL/lymphoma 9-like
chr2_-_119477613 2.841 ENSMUST00000110808.1
ENSMUST00000049920.7
Ino80

INO80 homolog (S. cerevisiae)

chr18_+_69346143 2.822 ENSMUST00000114980.1
Tcf4
transcription factor 4
chr2_-_120850364 2.717 ENSMUST00000131389.1
Ttbk2
tau tubulin kinase 2
chrX_-_104201126 2.706 ENSMUST00000056502.6
ENSMUST00000118314.1
C77370

expressed sequence C77370

chr8_-_11008458 2.692 ENSMUST00000040514.6
Irs2
insulin receptor substrate 2
chr1_-_56969864 2.690 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr12_+_102949450 2.688 ENSMUST00000179002.1
Unc79
unc-79 homolog (C. elegans)
chr4_+_144893077 2.608 ENSMUST00000154208.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr1_-_119422239 2.459 ENSMUST00000038765.5
Inhbb
inhibin beta-B
chr4_-_154636831 2.456 ENSMUST00000030902.6
ENSMUST00000105637.1
ENSMUST00000070313.7
ENSMUST00000105636.1
ENSMUST00000105638.2
ENSMUST00000097759.2
ENSMUST00000124771.1
Prdm16






PR domain containing 16






chr1_-_168431502 2.446 ENSMUST00000064438.4
Pbx1
pre B cell leukemia homeobox 1
chr5_+_64803513 2.439 ENSMUST00000165536.1
Klf3
Kruppel-like factor 3 (basic)
chr8_-_46294592 2.435 ENSMUST00000058636.7
Helt
helt bHLH transcription factor
chr1_-_56969827 2.411 ENSMUST00000176759.1
Satb2
special AT-rich sequence binding protein 2
chr7_+_25282784 2.395 ENSMUST00000165239.1
Cic
capicua homolog (Drosophila)
chr15_-_100599864 2.392 ENSMUST00000177247.2
ENSMUST00000177505.2
Pou6f1

POU domain, class 6, transcription factor 1

chrX_+_151803642 2.382 ENSMUST00000156616.2
Huwe1
HECT, UBA and WWE domain containing 1
chr2_-_146511899 2.303 ENSMUST00000131824.1
Ralgapa2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr1_-_56971762 2.303 ENSMUST00000114415.3
Satb2
special AT-rich sequence binding protein 2
chr2_-_29253001 2.278 ENSMUST00000071201.4
Ntng2
netrin G2
chrX_+_9199865 2.228 ENSMUST00000069763.2
Lancl3
LanC lantibiotic synthetase component C-like 3 (bacterial)
chr6_+_4903298 2.220 ENSMUST00000035813.2
Ppp1r9a
protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr8_+_70501116 2.217 ENSMUST00000127983.1
Crlf1
cytokine receptor-like factor 1
chr2_-_45113216 2.201 ENSMUST00000124942.1
Zeb2
zinc finger E-box binding homeobox 2
chr11_-_69801716 2.200 ENSMUST00000011285.4
ENSMUST00000102585.1
Fgf11

fibroblast growth factor 11

chr2_-_161109017 2.168 ENSMUST00000039782.7
ENSMUST00000134178.1
Chd6

chromodomain helicase DNA binding protein 6

chr5_-_25498748 2.142 ENSMUST00000173174.1
Kmt2c
lysine (K)-specific methyltransferase 2C
chr7_+_122289297 2.135 ENSMUST00000064989.5
ENSMUST00000064921.4
Prkcb

protein kinase C, beta

chr8_+_12385769 2.127 ENSMUST00000080795.8
Gm5607
predicted gene 5607
chr18_+_69345721 2.113 ENSMUST00000078486.6
ENSMUST00000114982.1
Tcf4

transcription factor 4

chr2_-_45113255 2.089 ENSMUST00000068415.4
ENSMUST00000127520.1
Zeb2

zinc finger E-box binding homeobox 2

chr15_+_102406143 2.085 ENSMUST00000170884.1
ENSMUST00000165924.1
ENSMUST00000163709.1
ENSMUST00000001326.6
Sp1



trans-acting transcription factor 1



chr16_-_4213404 2.042 ENSMUST00000023165.6
Crebbp
CREB binding protein
chr14_+_21500879 2.033 ENSMUST00000182964.1
Kat6b
K(lysine) acetyltransferase 6B
chr11_+_69765899 1.991 ENSMUST00000108640.1
ENSMUST00000108639.1
Zbtb4

zinc finger and BTB domain containing 4

chr2_+_128126030 1.982 ENSMUST00000089634.5
ENSMUST00000019281.7
ENSMUST00000110341.2
ENSMUST00000103211.1
ENSMUST00000103210.1
Bcl2l11




BCL2-like 11 (apoptosis facilitator)




chr10_+_127705170 1.964 ENSMUST00000079590.5
Myo1a
myosin IA
chr14_-_54781886 1.962 ENSMUST00000022787.6
Slc7a8
solute carrier family 7 (cationic amino acid transporter, y+ system), member 8
chr4_-_151861667 1.935 ENSMUST00000169423.2
Camta1
calmodulin binding transcription activator 1
chr18_-_43393346 1.930 ENSMUST00000025379.7
Dpysl3
dihydropyrimidinase-like 3
chr12_-_31950210 1.928 ENSMUST00000176084.1
ENSMUST00000176103.1
ENSMUST00000167458.2
Hbp1


high mobility group box transcription factor 1


chr4_-_3938354 1.884 ENSMUST00000003369.3
Plag1
pleiomorphic adenoma gene 1
chr1_+_59764264 1.820 ENSMUST00000087435.5
Bmpr2
bone morphogenetic protein receptor, type II (serine/threonine kinase)
chr6_-_28261907 1.813 ENSMUST00000115320.1
ENSMUST00000123098.1
ENSMUST00000115321.2
ENSMUST00000155494.1
Zfp800



zinc finger protein 800



chr5_-_25498702 1.811 ENSMUST00000173073.1
ENSMUST00000045291.7
Kmt2c

lysine (K)-specific methyltransferase 2C

chr3_-_95217741 1.801 ENSMUST00000107204.1
Gabpb2
GA repeat binding protein, beta 2
chr4_+_119539716 1.800 ENSMUST00000137560.1
Foxj3
forkhead box J3
chr12_-_118301429 1.791 ENSMUST00000026367.9
Sp4
trans-acting transcription factor 4
chr5_+_19227046 1.777 ENSMUST00000088516.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr14_-_51913393 1.775 ENSMUST00000004673.7
ENSMUST00000111632.3
Ndrg2

N-myc downstream regulated gene 2

chr11_+_84179852 1.765 ENSMUST00000136463.2
Acaca
acetyl-Coenzyme A carboxylase alpha
chr2_-_162661075 1.765 ENSMUST00000109442.1
ENSMUST00000109445.2
ENSMUST00000109443.1
ENSMUST00000109441.1
Ptprt



protein tyrosine phosphatase, receptor type, T



chr4_-_45012093 1.747 ENSMUST00000131991.1
Zbtb5
zinc finger and BTB domain containing 5
chr5_+_137350371 1.745 ENSMUST00000166239.1
ENSMUST00000111054.1
Ephb4

Eph receptor B4

chr6_-_136173492 1.745 ENSMUST00000111905.1
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr12_-_31950170 1.730 ENSMUST00000176520.1
Hbp1
high mobility group box transcription factor 1
chr1_-_168431896 1.714 ENSMUST00000176540.1
Pbx1
pre B cell leukemia homeobox 1
chr5_+_75152274 1.694 ENSMUST00000000476.8
Pdgfra
platelet derived growth factor receptor, alpha polypeptide
chr6_+_29433248 1.691 ENSMUST00000101617.2
ENSMUST00000065090.5
Flnc

filamin C, gamma

chrX_-_160994665 1.668 ENSMUST00000087104.4
Cdkl5
cyclin-dependent kinase-like 5
chr2_-_120850389 1.634 ENSMUST00000143051.1
ENSMUST00000057135.7
ENSMUST00000085840.4
Ttbk2


tau tubulin kinase 2


chr10_+_13966268 1.623 ENSMUST00000015645.4
Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr2_+_153031852 1.622 ENSMUST00000037235.6
Xkr7
X Kell blood group precursor related family member 7 homolog
chr4_-_118179946 1.618 ENSMUST00000050288.8
ENSMUST00000106403.1
Kdm4a

lysine (K)-specific demethylase 4A

chr5_+_137350101 1.608 ENSMUST00000061244.8
Ephb4
Eph receptor B4
chr14_+_116925379 1.608 ENSMUST00000088483.3
Gpc6
glypican 6
chr14_+_116925516 1.603 ENSMUST00000125435.1
Gpc6
glypican 6
chr11_-_69605829 1.598 ENSMUST00000047889.6
Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr18_+_34777008 1.589 ENSMUST00000043775.7
Kdm3b
KDM3B lysine (K)-specific demethylase 3B
chr9_+_100643755 1.570 ENSMUST00000133388.1
Stag1
stromal antigen 1
chr2_-_156392829 1.558 ENSMUST00000088578.2
2900097C17Rik
RIKEN cDNA 2900097C17 gene
chr7_+_97579868 1.556 ENSMUST00000042399.7
ENSMUST00000107153.1
Rsf1

remodeling and spacing factor 1

chr2_-_45112890 1.549 ENSMUST00000076836.6
Zeb2
zinc finger E-box binding homeobox 2
chr2_-_146511992 1.517 ENSMUST00000109986.2
Ralgapa2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr3_-_89393294 1.515 ENSMUST00000142119.1
ENSMUST00000029677.8
ENSMUST00000148361.1
Zbtb7b


zinc finger and BTB domain containing 7B


chr4_+_152338619 1.514 ENSMUST00000030775.5
ENSMUST00000164662.1
Chd5

chromodomain helicase DNA binding protein 5

chr3_+_28263205 1.506 ENSMUST00000159236.2
Tnik
TRAF2 and NCK interacting kinase
chr5_+_137350162 1.504 ENSMUST00000111055.2
Ephb4
Eph receptor B4
chr13_-_29984219 1.492 ENSMUST00000146092.1
E2f3
E2F transcription factor 3
chr11_-_6065538 1.460 ENSMUST00000101585.3
ENSMUST00000066431.7
ENSMUST00000109815.2
ENSMUST00000109812.2
ENSMUST00000101586.2
ENSMUST00000093355.5
ENSMUST00000019133.4
Camk2b






calcium/calmodulin-dependent protein kinase II, beta






chr1_+_158362330 1.449 ENSMUST00000170718.1
Astn1
astrotactin 1
chr2_+_57237651 1.447 ENSMUST00000169687.1
Gpd2
glycerol phosphate dehydrogenase 2, mitochondrial
chr9_+_31280525 1.445 ENSMUST00000117389.1
Prdm10
PR domain containing 10
chr7_+_30291941 1.426 ENSMUST00000144508.1
Clip3
CAP-GLY domain containing linker protein 3
chr15_-_50890041 1.402 ENSMUST00000077935.5
Trps1
trichorhinophalangeal syndrome I (human)
chr11_-_88718165 1.380 ENSMUST00000107908.1
Msi2
musashi RNA-binding protein 2
chr17_+_78200240 1.380 ENSMUST00000112498.2
Crim1
cysteine rich transmembrane BMP regulator 1 (chordin like)
chr17_-_34121944 1.369 ENSMUST00000151986.1
Brd2
bromodomain containing 2
chr6_+_6863269 1.347 ENSMUST00000160937.2
ENSMUST00000171311.1
Dlx6

distal-less homeobox 6

chr9_-_59036387 1.344 ENSMUST00000068664.5
Neo1
neogenin
chr8_-_31918203 1.332 ENSMUST00000073884.4
Nrg1
neuregulin 1
chr11_+_98203314 1.327 ENSMUST00000003203.7
ENSMUST00000107538.1
Cdk12

cyclin-dependent kinase 12

chr2_-_116065047 1.325 ENSMUST00000028639.6
ENSMUST00000102538.4
Meis2

Meis homeobox 2

chrX_+_99042581 1.319 ENSMUST00000036606.7
Stard8
START domain containing 8
chr10_+_79854658 1.312 ENSMUST00000171599.1
ENSMUST00000095457.4
Ptbp1

polypyrimidine tract binding protein 1

chr10_+_79854618 1.307 ENSMUST00000165704.1
Ptbp1
polypyrimidine tract binding protein 1
chr1_-_189343704 1.300 ENSMUST00000180044.1
ENSMUST00000110920.1
Kcnk2

potassium channel, subfamily K, member 2

chr3_-_95217877 1.284 ENSMUST00000136139.1
Gabpb2
GA repeat binding protein, beta 2
chr3_-_95217690 1.271 ENSMUST00000107209.1
Gabpb2
GA repeat binding protein, beta 2
chr11_-_88718078 1.264 ENSMUST00000092794.5
Msi2
musashi RNA-binding protein 2
chr8_+_22859528 1.263 ENSMUST00000110696.1
ENSMUST00000044331.6
Kat6a

K(lysine) acetyltransferase 6A

chr7_-_80405425 1.249 ENSMUST00000107362.3
ENSMUST00000135306.1
Furin

furin (paired basic amino acid cleaving enzyme)

chr1_-_191397026 1.248 ENSMUST00000067976.3
Ppp2r5a
protein phosphatase 2, regulatory subunit B (B56), alpha isoform
chr11_+_97663366 1.245 ENSMUST00000044730.5
Mllt6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr10_-_127666598 1.245 ENSMUST00000099157.3
Nab2
Ngfi-A binding protein 2
chr14_+_62837679 1.242 ENSMUST00000014691.8
Wdfy2
WD repeat and FYVE domain containing 2
chr11_-_97187872 1.241 ENSMUST00000001479.4
Kpnb1
karyopherin (importin) beta 1
chr5_+_118560719 1.240 ENSMUST00000100816.4
Med13l
mediator complex subunit 13-like
chr13_-_101768154 1.240 ENSMUST00000055518.6
Pik3r1
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)
chr14_+_46882854 1.233 ENSMUST00000022386.8
ENSMUST00000100672.3
Samd4

sterile alpha motif domain containing 4

chrX_+_13071470 1.230 ENSMUST00000169594.2
Usp9x
ubiquitin specific peptidase 9, X chromosome
chr4_-_118180043 1.227 ENSMUST00000106406.2
Kdm4a
lysine (K)-specific demethylase 4A
chr10_+_106470281 1.217 ENSMUST00000029404.9
ENSMUST00000169303.1
Ppfia2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chrX_-_105928547 1.210 ENSMUST00000101305.2
Atrx
alpha thalassemia/mental retardation syndrome X-linked homolog (human)
chr1_-_189343342 1.208 ENSMUST00000079451.6
Kcnk2
potassium channel, subfamily K, member 2
chr16_-_38713235 1.196 ENSMUST00000023487.4
Arhgap31
Rho GTPase activating protein 31
chr18_-_39490649 1.176 ENSMUST00000115567.1
Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr7_+_28180272 1.167 ENSMUST00000173223.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr2_-_120850598 1.162 ENSMUST00000028740.4
Ttbk2
tau tubulin kinase 2
chr7_+_4119556 1.159 ENSMUST00000079415.5
Ttyh1
tweety homolog 1 (Drosophila)
chr7_+_4119525 1.159 ENSMUST00000119661.1
ENSMUST00000129423.1
Ttyh1

tweety homolog 1 (Drosophila)

chr19_-_3686549 1.137 ENSMUST00000025856.10
ENSMUST00000176867.1
Lrp5

low density lipoprotein receptor-related protein 5

chr7_-_66689474 1.129 ENSMUST00000068980.3
Asb7
ankyrin repeat and SOCS box-containing 7
chr4_+_152338887 1.120 ENSMUST00000005175.4
Chd5
chromodomain helicase DNA binding protein 5
chr4_-_24430838 1.103 ENSMUST00000183964.1
RP23-35K5.2
RP23-35K5.2
chr13_-_105054895 1.096 ENSMUST00000063551.5
Rgs7bp
regulator of G-protein signalling 7 binding protein
chr5_-_3803081 1.095 ENSMUST00000043551.6
Ankib1
ankyrin repeat and IBR domain containing 1
chr11_+_77216180 1.093 ENSMUST00000037912.5
ENSMUST00000156488.1
Ssh2

slingshot homolog 2 (Drosophila)

chr14_-_70520254 1.093 ENSMUST00000022693.7
Bmp1
bone morphogenetic protein 1
chr19_-_4397052 1.093 ENSMUST00000075856.4
Kdm2a
lysine (K)-specific demethylase 2A
chr6_+_92091378 1.091 ENSMUST00000113460.1
Nr2c2
nuclear receptor subfamily 2, group C, member 2
chr7_+_28180226 1.090 ENSMUST00000172467.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr15_-_8444449 1.086 ENSMUST00000052965.6
Nipbl
Nipped-B homolog (Drosophila)
chr9_+_72532609 1.079 ENSMUST00000183372.1
ENSMUST00000184015.1
Rfx7

regulatory factor X, 7

chr14_+_116925291 1.078 ENSMUST00000078849.4
Gpc6
glypican 6
chr18_+_64340225 1.077 ENSMUST00000175965.2
ENSMUST00000115145.3
Onecut2

one cut domain, family member 2

chr1_-_72874877 1.073 ENSMUST00000027377.8
Igfbp5
insulin-like growth factor binding protein 5
chr11_+_121702591 1.070 ENSMUST00000125580.1
Metrnl
meteorin, glial cell differentiation regulator-like
chr14_+_20929416 1.061 ENSMUST00000022369.7
Vcl
vinculin
chr16_+_20673264 1.053 ENSMUST00000154950.1
ENSMUST00000115461.1
Eif4g1

eukaryotic translation initiation factor 4, gamma 1

chrX_+_101254528 1.044 ENSMUST00000062000.4
Foxo4
forkhead box O4
chr10_-_127621107 1.030 ENSMUST00000049149.8
Lrp1
low density lipoprotein receptor-related protein 1
chr4_+_129461581 1.017 ENSMUST00000048162.8
ENSMUST00000138013.1
Bsdc1

BSD domain containing 1

chr12_+_3806513 1.014 ENSMUST00000172719.1
Dnmt3a
DNA methyltransferase 3A
chr11_-_101984749 1.008 ENSMUST00000176261.1
ENSMUST00000143177.1
ENSMUST00000003612.6
Dusp3


dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related)


chr18_+_49832622 1.003 ENSMUST00000180611.1
Dmxl1
Dmx-like 1
chr1_-_168432270 1.003 ENSMUST00000072863.4
Pbx1
pre B cell leukemia homeobox 1
chr10_-_87493651 1.000 ENSMUST00000020243.7
Ascl1
achaete-scute complex homolog 1 (Drosophila)
chr4_-_118179628 0.991 ENSMUST00000097911.2
Kdm4a
lysine (K)-specific demethylase 4A
chr7_+_25282179 0.990 ENSMUST00000163320.1
ENSMUST00000005578.6
Cic

capicua homolog (Drosophila)

chr10_-_127666673 0.988 ENSMUST00000026469.2
Nab2
Ngfi-A binding protein 2
chr9_+_69397933 0.985 ENSMUST00000117610.1
ENSMUST00000145538.1
ENSMUST00000117246.1
Narg2


NMDA receptor-regulated gene 2


chr17_+_85620816 0.985 ENSMUST00000175898.2
Six3
sine oculis-related homeobox 3
chr10_+_127380799 0.984 ENSMUST00000111628.2
R3hdm2
R3H domain containing 2
chr4_-_41464816 0.976 ENSMUST00000108055.2
ENSMUST00000154535.1
ENSMUST00000030148.5
Kif24


kinesin family member 24


chr6_-_120038647 0.971 ENSMUST00000088646.5
ENSMUST00000177761.1
ENSMUST00000088644.6
ENSMUST00000060043.6
Wnk1



WNK lysine deficient protein kinase 1



chr17_-_45686120 0.958 ENSMUST00000143907.1
ENSMUST00000127065.1
Tmem63b

transmembrane protein 63b

chr2_+_117121374 0.955 ENSMUST00000028829.6
Spred1
sprouty protein with EVH-1 domain 1, related sequence
chr17_-_35074485 0.952 ENSMUST00000007259.3
Ly6g6d
lymphocyte antigen 6 complex, locus G6D
chr4_-_128962420 0.948 ENSMUST00000119354.1
ENSMUST00000106068.1
ENSMUST00000030581.3
Adc


arginine decarboxylase


chr17_-_34122311 0.945 ENSMUST00000025193.6
Brd2
bromodomain containing 2
chr5_+_65764073 0.944 ENSMUST00000138239.1
ENSMUST00000087264.3
N4bp2

NEDD4 binding protein 2

chr11_+_108920800 0.943 ENSMUST00000140821.1
Axin2
axin2
chr17_+_33916171 0.941 ENSMUST00000053429.9
Zbtb22
zinc finger and BTB domain containing 22
chr11_+_98412461 0.938 ENSMUST00000058295.5
Erbb2
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
chr9_+_57072024 0.936 ENSMUST00000169879.1
Sin3a
transcriptional regulator, SIN3A (yeast)
chrX_+_77511002 0.932 ENSMUST00000088217.5
Tbl1x
transducin (beta)-like 1 X-linked
chr4_-_151861762 0.931 ENSMUST00000097774.2
Camta1
calmodulin binding transcription activator 1

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.8 14.3 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
3.0 11.9 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
2.0 5.9 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
1.6 6.4 GO:0060032 notochord regression(GO:0060032)
1.3 3.9 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
1.2 6.2 GO:0007256 activation of JNKK activity(GO:0007256)
1.2 4.9 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
1.1 4.4 GO:0043974 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
1.1 3.2 GO:0060023 soft palate development(GO:0060023)
1.0 6.1 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
1.0 4.9 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.9 1.8 GO:2000793 cell proliferation involved in heart valve development(GO:2000793)
0.9 0.9 GO:1904048 regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.8 13.4 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.8 2.5 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.8 2.5 GO:0046881 positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.8 3.8 GO:0060178 regulation of exocyst localization(GO:0060178)
0.7 5.5 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.6 0.6 GO:0043585 nose morphogenesis(GO:0043585)
0.6 1.7 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.5 5.4 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.5 2.2 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.5 4.3 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.5 1.6 GO:0097402 neuroblast migration(GO:0097402)
0.5 2.0 GO:0045358 negative regulation of interferon-beta biosynthetic process(GO:0045358)
0.5 5.5 GO:0042572 retinol metabolic process(GO:0042572)
0.5 2.0 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139) apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.5 4.9 GO:0042118 endothelial cell activation(GO:0042118)
0.5 1.5 GO:0032430 inhibitory G-protein coupled receptor phosphorylation(GO:0002030) positive regulation of phospholipase A2 activity(GO:0032430) activation of meiosis involved in egg activation(GO:0060466)
0.5 2.7 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.4 1.3 GO:0021830 interneuron migration from the subpallium to the cortex(GO:0021830)
0.4 1.8 GO:0044268 multicellular organismal protein metabolic process(GO:0044268)
0.4 1.7 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.4 2.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.4 1.2 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.4 1.6 GO:1904398 positive regulation of neuromuscular junction development(GO:1904398)
0.4 1.2 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.4 3.7 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.4 1.6 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.4 0.8 GO:2000078 positive regulation of type B pancreatic cell development(GO:2000078)
0.4 0.4 GO:0045608 inhibition of neuroepithelial cell differentiation(GO:0002085) negative regulation of auditory receptor cell differentiation(GO:0045608)
0.4 3.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.4 2.6 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.4 3.8 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.4 1.5 GO:0003192 mitral valve formation(GO:0003192) condensed mesenchymal cell proliferation(GO:0072137)
0.4 2.2 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.3 3.8 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.3 0.7 GO:0021759 globus pallidus development(GO:0021759)
0.3 5.5 GO:1990403 embryonic brain development(GO:1990403)
0.3 1.0 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.3 8.5 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.3 1.0 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.3 2.2 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.3 0.9 GO:0070602 regulation of chondrocyte development(GO:0061181) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.3 0.9 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.3 1.2 GO:0090472 dibasic protein processing(GO:0090472)
0.3 1.2 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.3 1.2 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.3 1.5 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.3 2.1 GO:0070814 hydrogen sulfide biosynthetic process(GO:0070814)
0.3 2.4 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.3 1.4 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.3 0.8 GO:0070535 histone H2A K63-linked ubiquitination(GO:0070535) negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.3 1.1 GO:0061010 gall bladder development(GO:0061010)
0.3 2.7 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.3 1.6 GO:0072718 response to cisplatin(GO:0072718)
0.3 0.8 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.3 1.0 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.3 2.1 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.2 1.7 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.2 1.7 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.2 1.4 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.2 1.9 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.2 1.2 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.2 4.4 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.2 1.6 GO:0016584 nucleosome positioning(GO:0016584)
0.2 1.5 GO:2001185 regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.2 1.9 GO:0097154 GABAergic neuron differentiation(GO:0097154)
0.2 3.4 GO:0007379 segment specification(GO:0007379)
0.2 0.6 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.2 0.6 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.2 0.7 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.2 0.5 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.2 0.5 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.2 0.8 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.2 0.7 GO:0097494 regulation of vesicle size(GO:0097494)
0.2 1.1 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.2 1.2 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.2 0.9 GO:0036337 Fas signaling pathway(GO:0036337)
0.2 0.9 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.2 3.2 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.2 0.3 GO:2001027 negative regulation of antigen processing and presentation(GO:0002578) negative regulation of endothelial cell chemotaxis(GO:2001027)
0.2 1.5 GO:0071455 cellular response to hyperoxia(GO:0071455)
0.1 2.2 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 2.7 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.1 1.4 GO:0010459 negative regulation of heart rate(GO:0010459)
0.1 0.8 GO:0097646 dimeric G-protein coupled receptor signaling pathway(GO:0038042) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 1.5 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 2.2 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 0.4 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.1 1.3 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 1.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.4 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.1 0.6 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.5 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.1 0.7 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.1 0.4 GO:0015744 succinate transport(GO:0015744)
0.1 1.0 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.4 GO:0097298 regulation of nucleus size(GO:0097298)
0.1 1.2 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.1 0.4 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.1 1.9 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 0.4 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.1 3.6 GO:0007520 myoblast fusion(GO:0007520)
0.1 0.8 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 2.3 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.1 0.9 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.1 2.0 GO:0030033 microvillus assembly(GO:0030033)
0.1 1.1 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.6 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1 3.6 GO:0048599 oocyte development(GO:0048599)
0.1 1.2 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.1 1.5 GO:0060736 prostate gland growth(GO:0060736)
0.1 3.3 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.8 GO:0038203 TORC2 signaling(GO:0038203)
0.1 1.5 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.1 0.4 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.1 0.5 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.1 0.3 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1 0.3 GO:0019858 cytosine metabolic process(GO:0019858)
0.1 0.4 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 0.4 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.1 3.8 GO:0006284 base-excision repair(GO:0006284)
0.1 0.5 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.1 0.6 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 0.8 GO:0000042 protein targeting to Golgi(GO:0000042)
0.1 0.4 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.7 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.6 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 0.2 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 0.3 GO:0006558 L-phenylalanine metabolic process(GO:0006558) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221)
0.1 3.8 GO:0008542 visual learning(GO:0008542)
0.1 0.6 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 1.1 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.1 0.4 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.1 0.8 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.1 2.5 GO:0001755 neural crest cell migration(GO:0001755)
0.1 0.5 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.6 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.1 0.5 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.1 2.2 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.1 6.6 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.1 3.4 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.1 1.7 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 0.4 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.1 2.0 GO:0015804 neutral amino acid transport(GO:0015804)
0.1 0.2 GO:0060982 coronary artery morphogenesis(GO:0060982)
0.1 0.9 GO:0000338 protein deneddylation(GO:0000338)
0.1 0.2 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.1 0.3 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.1 0.4 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 0.4 GO:0036506 maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1 0.2 GO:1990859 cellular response to endothelin(GO:1990859)
0.1 0.2 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700) purinergic nucleotide receptor signaling pathway(GO:0035590) positive regulation of penile erection(GO:0060406)
0.1 0.1 GO:0060437 lung growth(GO:0060437)
0.1 0.6 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.6 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.1 GO:0009994 oocyte differentiation(GO:0009994)
0.0 0.0 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.9 GO:0010574 regulation of vascular endothelial growth factor production(GO:0010574)
0.0 0.8 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.8 GO:0048305 immunoglobulin secretion(GO:0048305)
0.0 0.9 GO:0007143 female meiotic division(GO:0007143)
0.0 0.9 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.2 GO:0002158 osteoclast proliferation(GO:0002158)
0.0 1.7 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.3 GO:1903351 response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
0.0 1.1 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 1.4 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 0.2 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 2.4 GO:0034333 adherens junction assembly(GO:0034333)
0.0 0.8 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 1.1 GO:0061036 positive regulation of cartilage development(GO:0061036)
0.0 0.6 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.3 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.3 GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.0 0.3 GO:0071578 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574) zinc II ion transmembrane import(GO:0071578)
0.0 0.2 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.5 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 4.5 GO:0007051 spindle organization(GO:0007051)
0.0 0.5 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:0001803 type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805) serotonin secretion by platelet(GO:0002554) positive regulation of mast cell cytokine production(GO:0032765) mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0 1.0 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.9 GO:0035065 regulation of histone acetylation(GO:0035065)
0.0 0.4 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.0 0.2 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.3 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.6 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.5 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.0 0.9 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.1 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.0 0.3 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.2 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.2 GO:0046959 habituation(GO:0046959)
0.0 0.5 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.8 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 1.2 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.0 1.9 GO:0008016 regulation of heart contraction(GO:0008016)
0.0 0.2 GO:0032060 bleb assembly(GO:0032060)
0.0 0.1 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.3 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.7 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.7 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 0.2 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0 0.2 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:0070230 positive regulation of lymphocyte apoptotic process(GO:0070230)
0.0 0.2 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.2 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.2 GO:0002931 response to ischemia(GO:0002931)
0.0 0.2 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 1.7 GO:0050714 positive regulation of protein secretion(GO:0050714)
0.0 0.2 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.0 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.1 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.1 GO:0031100 organ regeneration(GO:0031100)
0.0 0.0 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.4 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.0 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.0 0.2 GO:0051310 metaphase plate congression(GO:0051310)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.3 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.7 GO:0071953 elastic fiber(GO:0071953)
1.2 5.9 GO:1990761 growth cone lamellipodium(GO:1990761)
1.1 3.4 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.9 3.6 GO:0043259 laminin-10 complex(GO:0043259)
0.8 4.0 GO:0044666 MLL3/4 complex(GO:0044666)
0.8 2.3 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.7 2.2 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.6 1.9 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.6 2.5 GO:0043511 inhibin complex(GO:0043511)
0.5 6.4 GO:0097542 ciliary tip(GO:0097542)
0.5 2.7 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.4 2.5 GO:0044305 calyx of Held(GO:0044305)
0.3 5.4 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.3 1.2 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.3 7.0 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.3 1.4 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.3 1.2 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.3 1.1 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.2 3.8 GO:0005721 pericentric heterochromatin(GO:0005721)
0.2 1.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.2 0.7 GO:0034679 integrin alpha9-beta1 complex(GO:0034679)
0.2 1.9 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 1.3 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.2 4.1 GO:0010369 chromocenter(GO:0010369)
0.2 2.7 GO:0043083 synaptic cleft(GO:0043083)
0.2 2.8 GO:0031011 Ino80 complex(GO:0031011)
0.2 1.7 GO:0044294 dendritic growth cone(GO:0044294)
0.2 3.6 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.2 2.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.2 13.6 GO:0000118 histone deacetylase complex(GO:0000118)
0.2 0.5 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
0.2 0.8 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.2 4.1 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.2 14.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.2 1.2 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.2 1.7 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.2 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.1 1.0 GO:0044327 dendritic spine head(GO:0044327)
0.1 0.7 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 1.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 5.5 GO:0035869 ciliary transition zone(GO:0035869)
0.1 1.4 GO:0005916 fascia adherens(GO:0005916)
0.1 0.6 GO:1990246 uniplex complex(GO:1990246)
0.1 0.8 GO:0032584 growth cone membrane(GO:0032584)
0.1 3.6 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 5.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 1.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 5.0 GO:0009925 basal plasma membrane(GO:0009925)
0.1 2.8 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 0.6 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 8.3 GO:0055037 recycling endosome(GO:0055037)
0.1 0.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.8 GO:0061700 GATOR2 complex(GO:0061700)
0.1 10.2 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 0.4 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 0.7 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 1.9 GO:0016592 mediator complex(GO:0016592)
0.1 1.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.8 GO:0045180 basal cortex(GO:0045180)
0.1 1.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.7 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 1.4 GO:0051233 spindle midzone(GO:0051233)
0.0 3.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.7 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.5 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 1.2 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.5 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 5.1 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.4 GO:0005605 basal lamina(GO:0005605)
0.0 0.4 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.8 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.2 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.3 GO:0000346 transcription export complex(GO:0000346)
0.0 1.3 GO:0030673 axolemma(GO:0030673)
0.0 0.5 GO:0097440 apical dendrite(GO:0097440)
0.0 0.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.8 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.6 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.3 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.1 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 1.8 GO:0005844 polysome(GO:0005844)
0.0 2.1 GO:0016528 sarcoplasm(GO:0016528)
0.0 0.4 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 1.6 GO:0031526 brush border membrane(GO:0031526)
0.0 0.2 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.5 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.5 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.9 GO:0031941 filamentous actin(GO:0031941)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 4.7 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.9 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.3 GO:0031143 pseudopodium(GO:0031143)
0.0 0.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 2.4 GO:0044306 neuron projection terminus(GO:0044306)
0.0 0.3 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.6 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.9 GO:0031201 SNARE complex(GO:0031201)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.4 GO:0005814 centriole(GO:0005814)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.4 GO:0030118 clathrin coat(GO:0030118)
0.0 0.4 GO:0000795 synaptonemal complex(GO:0000795)
0.0 9.5 GO:0016604 nuclear body(GO:0016604)
0.0 3.0 GO:0043235 receptor complex(GO:0043235)
0.0 0.4 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0030015 CCR4-NOT core complex(GO:0030015)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 11.9 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
2.9 14.3 GO:0005030 neurotrophin receptor activity(GO:0005030)
1.2 4.9 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
1.1 5.4 GO:1990188 euchromatin binding(GO:1990188)
0.8 3.4 GO:0050436 microfibril binding(GO:0050436)
0.8 5.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.8 4.5 GO:0045322 unmethylated CpG binding(GO:0045322)
0.7 2.6 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.6 1.8 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.6 2.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.6 4.5 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.5 2.0 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
0.5 1.4 GO:0016901 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.5 1.9 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.4 6.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.4 2.6 GO:0001069 regulatory region RNA binding(GO:0001069)
0.4 4.1 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.4 1.1 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.4 2.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.3 2.1 GO:0097001 ceramide binding(GO:0097001)
0.3 1.7 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.3 4.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.3 2.2 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.3 0.9 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.3 2.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.3 1.8 GO:0070699 type II activin receptor binding(GO:0070699)
0.3 1.2 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.3 2.3 GO:0070087 chromo shadow domain binding(GO:0070087)
0.3 4.9 GO:0005003 ephrin receptor activity(GO:0005003)
0.3 2.3 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529)
0.3 5.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.3 1.8 GO:0098821 BMP receptor activity(GO:0098821)
0.3 1.0 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.2 2.0 GO:0019534 toxin transporter activity(GO:0019534)
0.2 1.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.2 0.9 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.2 2.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.2 0.8 GO:0048495 Roundabout binding(GO:0048495)
0.2 7.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 4.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.2 1.6 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.2 0.7 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.2 1.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.2 6.6 GO:0070412 R-SMAD binding(GO:0070412)
0.2 0.8 GO:0097643 amylin receptor activity(GO:0097643)
0.2 1.5 GO:0008420 CTD phosphatase activity(GO:0008420)
0.2 1.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.2 1.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.2 0.9 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.2 0.9 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.2 0.9 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.2 0.3 GO:0070052 collagen V binding(GO:0070052)
0.1 0.4 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.1 1.3 GO:0039706 co-receptor binding(GO:0039706)
0.1 1.5 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 4.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.8 GO:0005042 netrin receptor activity(GO:0005042)
0.1 1.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 1.3 GO:0045499 chemorepellent activity(GO:0045499)
0.1 2.9 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.5 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.9 GO:0070411 I-SMAD binding(GO:0070411)
0.1 1.2 GO:0001727 lipid kinase activity(GO:0001727)
0.1 0.4 GO:0004104 cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.1 0.5 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.5 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.6 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.4 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.1 0.3 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 9.0 GO:0001012 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.1 0.6 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 2.1 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 2.5 GO:0046332 SMAD binding(GO:0046332)
0.1 3.1 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 0.6 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 0.5 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 2.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.5 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.3 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 4.5 GO:0001221 transcription cofactor binding(GO:0001221)
0.1 2.4 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 2.1 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.3 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1 0.4 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 0.5 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.4 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 1.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.3 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.4 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.1 0.2 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.1 6.0 GO:0008013 beta-catenin binding(GO:0008013)
0.1 2.4 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 2.9 GO:0005158 insulin receptor binding(GO:0005158)
0.1 6.2 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 1.4 GO:0030506 ankyrin binding(GO:0030506)
0.1 2.8 GO:0003678 DNA helicase activity(GO:0003678)
0.1 1.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 1.2 GO:0070840 dynein complex binding(GO:0070840)
0.1 0.1 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.1 0.5 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 1.0 GO:0043274 phospholipase binding(GO:0043274)
0.0 2.6 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.8 GO:0015491 cation:cation antiporter activity(GO:0015491)
0.0 0.6 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 1.1 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 1.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.2 GO:0004667 prostaglandin-D synthase activity(GO:0004667) prostaglandin-E synthase activity(GO:0050220)
0.0 0.6 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.7 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.6 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.5 GO:0019104 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906) DNA N-glycosylase activity(GO:0019104)
0.0 0.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.6 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.7 GO:0005179 hormone activity(GO:0005179)
0.0 0.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 8.2 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.5 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.7 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 1.3 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 2.8 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.3 GO:0017166 vinculin binding(GO:0017166)
0.0 0.4 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 1.1 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0005118 sevenless binding(GO:0005118)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.4 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 2.6 GO:0004713 protein tyrosine kinase activity(GO:0004713)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 1.2 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 1.4 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.4 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.4 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.3 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.2 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.5 GO:0032934 cholesterol binding(GO:0015485) sterol binding(GO:0032934)
0.0 0.0 GO:0036361 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.0 0.9 GO:0005178 integrin binding(GO:0005178)
0.0 0.2 GO:0000030 mannosyltransferase activity(GO:0000030)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.1 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.3 11.5 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2 2.6 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 2.2 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.2 13.4 PID_SHP2_PATHWAY SHP2 signaling
0.2 8.6 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 1.8 PID_ALK2_PATHWAY ALK2 signaling events
0.2 2.7 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.1 2.9 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 3.7 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.1 2.8 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.1 2.7 PID_EPO_PATHWAY EPO signaling pathway
0.1 3.8 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.1 6.7 PID_TNF_PATHWAY TNF receptor signaling pathway
0.1 0.9 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.1 3.0 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 8.3 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.1 6.0 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 4.3 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 1.6 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.1 1.6 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.1 0.7 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.1 1.1 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.1 0.8 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.1 0.6 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.1 4.6 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 3.3 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 1.2 PID_REELIN_PATHWAY Reelin signaling pathway
0.0 5.8 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 2.2 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 1.4 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.6 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 3.7 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.9 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 1.6 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.6 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.0 0.6 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.0 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 0.4 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 4.2 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 0.9 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 0.7 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.9 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 0.2 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.2 4.8 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.2 1.3 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 2.4 REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 5.5 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 1.2 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 1.2 REACTOME_PLATELET_SENSITIZATION_BY_LDL Genes involved in Platelet sensitization by LDL
0.1 2.8 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.1 4.1 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.1 3.2 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 3.3 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.1 1.5 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 2.3 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 2.3 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.3 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.1 0.4 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 2.1 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 1.5 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 1.1 REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.1 0.5 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 0.8 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 2.0 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 1.9 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 0.9 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.2 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 4.5 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 1.6 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 0.4 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.1 0.9 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.7 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 0.7 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.6 REACTOME_PIP3_ACTIVATES_AKT_SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 1.6 REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.5 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 1.2 REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.4 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.5 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.5 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.3 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.9 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.5 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.4 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 1.0 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.8 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.5 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 3.3 REACTOME_FATTY_ACID_TRIACYLGLYCEROL_AND_KETONE_BODY_METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.0 2.3 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 2.8 REACTOME_CHROMOSOME_MAINTENANCE Genes involved in Chromosome Maintenance
0.0 0.2 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.3 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.6 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.1 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.4 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.1 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.2 REACTOME_ELONGATION_ARREST_AND_RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.1 REACTOME_ACYL_CHAIN_REMODELLING_OF_PS Genes involved in Acyl chain remodelling of PS
0.0 1.2 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 1.6 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.2 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.6 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)