Motif ID: Zbtb7a

Z-value: 0.931


Transcription factors associated with Zbtb7a:

Gene SymbolEntrez IDGene Name
Zbtb7a ENSMUSG00000035011.9 Zbtb7a

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb7amm10_v2_chr10_+_81136534_811366080.342.8e-02Click!


Activity profile for motif Zbtb7a.

activity profile for motif Zbtb7a


Sorted Z-values histogram for motif Zbtb7a

Sorted Z-values for motif Zbtb7a



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb7a

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_107036156 3.891 ENSMUST00000052718.3
Kcna3
potassium voltage-gated channel, shaker-related subfamily, member 3
chr7_+_96210107 3.858 ENSMUST00000138760.1
Tenm4
teneurin transmembrane protein 4
chr9_-_44234014 3.798 ENSMUST00000037644.6
Cbl
Casitas B-lineage lymphoma
chr11_+_75532127 2.995 ENSMUST00000127226.1
Slc43a2
solute carrier family 43, member 2
chr18_+_32938955 2.934 ENSMUST00000042868.4
Camk4
calcium/calmodulin-dependent protein kinase IV
chr8_-_34965631 2.723 ENSMUST00000033929.4
Tnks
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr11_-_107915041 2.713 ENSMUST00000039071.2
Cacng5
calcium channel, voltage-dependent, gamma subunit 5
chr11_+_75531690 2.700 ENSMUST00000149727.1
ENSMUST00000042561.7
ENSMUST00000108433.1
ENSMUST00000143035.1
Slc43a2



solute carrier family 43, member 2



chr8_-_11008458 2.625 ENSMUST00000040514.6
Irs2
insulin receptor substrate 2
chr11_+_24076529 2.603 ENSMUST00000148087.1
Gm12063
predicted gene 12063
chr4_-_123664725 2.559 ENSMUST00000147030.1
Macf1
microtubule-actin crosslinking factor 1
chr9_+_67840386 2.487 ENSMUST00000077879.5
Vps13c
vacuolar protein sorting 13C (yeast)
chrX_+_159697308 2.486 ENSMUST00000123433.1
Sh3kbp1
SH3-domain kinase binding protein 1
chr1_-_155417394 2.460 ENSMUST00000111775.1
ENSMUST00000111774.1
Xpr1

xenotropic and polytropic retrovirus receptor 1

chrX_+_71364901 2.452 ENSMUST00000132837.1
Mtmr1
myotubularin related protein 1
chr15_-_72546279 2.443 ENSMUST00000044624.6
Kcnk9
potassium channel, subfamily K, member 9
chr7_+_49246812 2.351 ENSMUST00000184945.1
Nav2
neuron navigator 2
chr2_-_29253001 2.261 ENSMUST00000071201.4
Ntng2
netrin G2
chr1_-_154725920 2.238 ENSMUST00000004214.8
Cacna1e
calcium channel, voltage-dependent, R type, alpha 1E subunit
chr15_-_98567630 2.226 ENSMUST00000012104.6
Ccnt1
cyclin T1
chr15_-_100599864 2.218 ENSMUST00000177247.2
ENSMUST00000177505.2
Pou6f1

POU domain, class 6, transcription factor 1

chr5_+_37028329 2.182 ENSMUST00000173836.1
Jakmip1
janus kinase and microtubule interacting protein 1
chr6_+_54681687 2.158 ENSMUST00000046276.6
2410066E13Rik
RIKEN cDNA 2410066E13 gene
chr9_+_100643755 2.044 ENSMUST00000133388.1
Stag1
stromal antigen 1
chr17_-_17624458 1.964 ENSMUST00000041047.2
Lnpep
leucyl/cystinyl aminopeptidase
chr19_-_42431778 1.917 ENSMUST00000048630.6
Crtac1
cartilage acidic protein 1
chr13_-_59556845 1.894 ENSMUST00000170378.1
ENSMUST00000169434.1
Agtpbp1

ATP/GTP binding protein 1

chr10_-_127263346 1.832 ENSMUST00000099172.3
Kif5a
kinesin family member 5A
chr13_+_92611119 1.830 ENSMUST00000049488.7
Serinc5
serine incorporator 5
chr2_+_28513105 1.815 ENSMUST00000135803.1
Ralgds
ral guanine nucleotide dissociation stimulator
chr6_-_126645784 1.813 ENSMUST00000055168.3
Kcna1
potassium voltage-gated channel, shaker-related subfamily, member 1
chr9_+_31280525 1.787 ENSMUST00000117389.1
Prdm10
PR domain containing 10
chr17_+_6270475 1.770 ENSMUST00000088940.4
Tmem181a
transmembrane protein 181A
chr16_+_11984581 1.759 ENSMUST00000170672.2
ENSMUST00000023138.7
Shisa9

shisa homolog 9 (Xenopus laevis)

chr7_-_73537621 1.759 ENSMUST00000172704.1
Chd2
chromodomain helicase DNA binding protein 2
chr7_-_27929430 1.734 ENSMUST00000098639.2
1700049G17Rik
RIKEN cDNA 1700049G17 gene
chr17_-_78835326 1.700 ENSMUST00000097281.2
Heatr5b
HEAT repeat containing 5B
chr16_+_91729436 1.698 ENSMUST00000113993.1
Itsn1
intersectin 1 (SH3 domain protein 1A)
chr11_+_75532099 1.695 ENSMUST00000169547.2
Slc43a2
solute carrier family 43, member 2
chr2_+_28533355 1.694 ENSMUST00000113893.1
ENSMUST00000100241.3
Ralgds

ral guanine nucleotide dissociation stimulator

chr11_+_68692070 1.692 ENSMUST00000108673.1
Myh10
myosin, heavy polypeptide 10, non-muscle
chr5_+_130144861 1.680 ENSMUST00000040616.2
Kctd7
potassium channel tetramerisation domain containing 7
chr9_+_66350465 1.676 ENSMUST00000042824.6
Herc1
hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1
chr2_-_28840274 1.674 ENSMUST00000037117.5
ENSMUST00000171404.1
Gtf3c4

general transcription factor IIIC, polypeptide 4

chr16_+_91729281 1.611 ENSMUST00000114001.1
ENSMUST00000113999.1
ENSMUST00000064797.5
ENSMUST00000114002.2
ENSMUST00000095909.3
ENSMUST00000056482.7
ENSMUST00000113996.1
Itsn1






intersectin 1 (SH3 domain protein 1A)






chr11_+_3332426 1.606 ENSMUST00000136474.1
Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr2_+_180042496 1.595 ENSMUST00000041126.8
Ss18l1
synovial sarcoma translocation gene on chromosome 18-like 1
chr10_+_76531593 1.572 ENSMUST00000048678.6
Lss
lanosterol synthase
chr17_+_7170101 1.562 ENSMUST00000024575.6
Rps6ka2
ribosomal protein S6 kinase, polypeptide 2
chr11_+_115187481 1.530 ENSMUST00000100235.2
ENSMUST00000061450.6
Tmem104

transmembrane protein 104

chr18_+_35965088 1.517 ENSMUST00000175734.1
Psd2
pleckstrin and Sec7 domain containing 2
chr11_+_93996082 1.472 ENSMUST00000041956.7
Spag9
sperm associated antigen 9
chr11_-_118248489 1.472 ENSMUST00000100181.4
Cyth1
cytohesin 1
chr12_+_31265234 1.449 ENSMUST00000169088.1
Lamb1
laminin B1
chr11_-_70687917 1.437 ENSMUST00000108545.2
ENSMUST00000120261.1
ENSMUST00000036299.7
ENSMUST00000119120.1
ENSMUST00000100933.3
Camta2




calmodulin binding transcription activator 2




chr6_+_51432663 1.428 ENSMUST00000005103.5
Nfe2l3
nuclear factor, erythroid derived 2, like 3
chr16_+_36875119 1.413 ENSMUST00000135406.1
ENSMUST00000114812.1
ENSMUST00000134616.1
ENSMUST00000023534.6
Golgb1


Golgb1
golgi autoantigen, golgin subfamily b, macrogolgin 1


golgi autoantigen, golgin subfamily b, macrogolgin 1
chr16_+_10545390 1.411 ENSMUST00000115827.1
ENSMUST00000038145.6
ENSMUST00000150894.1
Clec16a


C-type lectin domain family 16, member A


chr15_-_28025834 1.408 ENSMUST00000090247.5
Trio
triple functional domain (PTPRF interacting)
chr8_+_40862379 1.404 ENSMUST00000098816.3
ENSMUST00000057784.8
ENSMUST00000141505.1
Slc7a2


solute carrier family 7 (cationic amino acid transporter, y+ system), member 2


chr2_-_160872829 1.386 ENSMUST00000176141.1
Zhx3
zinc fingers and homeoboxes 3
chr5_-_139129662 1.385 ENSMUST00000026973.7
Prkar1b
protein kinase, cAMP dependent regulatory, type I beta
chr1_-_155417283 1.378 ENSMUST00000027741.5
Xpr1
xenotropic and polytropic retrovirus receptor 1
chr4_+_119539652 1.377 ENSMUST00000044564.8
ENSMUST00000162267.1
ENSMUST00000106310.2
ENSMUST00000138845.2
Foxj3



forkhead box J3



chr12_+_86241848 1.365 ENSMUST00000071106.4
Gpatch2l
G patch domain containing 2 like
chr7_-_84086494 1.360 ENSMUST00000064174.5
9930013L23Rik
RIKEN cDNA 9930013L23 gene
chr13_+_54575020 1.345 ENSMUST00000156024.1
Arl10
ADP-ribosylation factor-like 10
chr4_+_136284658 1.322 ENSMUST00000144217.1
Zfp46
zinc finger protein 46
chrX_+_73503074 1.319 ENSMUST00000114479.1
ENSMUST00000088429.1
ENSMUST00000033744.5
Atp2b3


ATPase, Ca++ transporting, plasma membrane 3


chr1_+_132008285 1.318 ENSMUST00000146432.1
Elk4
ELK4, member of ETS oncogene family
chr9_+_15709715 1.314 ENSMUST00000115588.1
ENSMUST00000061568.7
Slc36a4

solute carrier family 36 (proton/amino acid symporter), member 4

chr17_-_66077022 1.308 ENSMUST00000150766.1
ENSMUST00000038116.5
Ankrd12

ankyrin repeat domain 12

chr2_-_160872985 1.305 ENSMUST00000109460.1
ENSMUST00000127201.1
Zhx3

zinc fingers and homeoboxes 3

chr2_+_172345565 1.303 ENSMUST00000028995.4
Fam210b
family with sequence similarity 210, member B
chr5_+_118027743 1.298 ENSMUST00000031304.7
Tesc
tescalcin
chr6_+_4601124 1.274 ENSMUST00000181734.1
ENSMUST00000141359.1
Casd1

CAS1 domain containing 1

chr1_-_21961581 1.259 ENSMUST00000029667.6
ENSMUST00000173058.1
ENSMUST00000173404.1
Kcnq5


potassium voltage-gated channel, subfamily Q, member 5


chr1_+_156558759 1.238 ENSMUST00000173929.1
Abl2
v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene)
chrX_+_71364745 1.230 ENSMUST00000114601.1
ENSMUST00000146213.1
ENSMUST00000015358.1
Mtmr1


myotubularin related protein 1


chr9_-_15045378 1.230 ENSMUST00000164273.1
Panx1
pannexin 1
chr10_-_79874211 1.224 ENSMUST00000167897.1
BC005764
cDNA sequence BC005764
chr11_-_116412965 1.219 ENSMUST00000100202.3
ENSMUST00000106398.2
Rnf157

ring finger protein 157

chr2_-_132385392 1.213 ENSMUST00000049997.7
ENSMUST00000145995.1
ENSMUST00000142766.1
ENSMUST00000110157.2
Prokr2



prokineticin receptor 2



chr7_+_127511976 1.209 ENSMUST00000098025.4
Srcap
Snf2-related CREBBP activator protein
chr4_+_85205417 1.203 ENSMUST00000030212.8
ENSMUST00000107189.1
ENSMUST00000107184.1
Sh3gl2


SH3-domain GRB2-like 2


chr4_+_119539716 1.200 ENSMUST00000137560.1
Foxj3
forkhead box J3
chr2_+_28840406 1.196 ENSMUST00000113853.2
Ddx31
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 31
chr4_+_43059028 1.193 ENSMUST00000163653.1
ENSMUST00000107952.2
ENSMUST00000107953.2
Unc13b


unc-13 homolog B (C. elegans)


chr19_+_54045182 1.178 ENSMUST00000036700.5
Adra2a
adrenergic receptor, alpha 2a
chr10_-_57532416 1.176 ENSMUST00000169122.1
Serinc1
serine incorporator 1
chr17_+_8340710 1.174 ENSMUST00000163887.1
Prr18
proline rich region 18
chr19_-_55099417 1.148 ENSMUST00000061856.5
Gpam
glycerol-3-phosphate acyltransferase, mitochondrial
chr4_+_136284708 1.147 ENSMUST00000130223.1
Zfp46
zinc finger protein 46
chr9_-_108190352 1.142 ENSMUST00000035208.7
Bsn
bassoon
chr4_-_151108244 1.138 ENSMUST00000131948.1
Camta1
calmodulin binding transcription activator 1
chr19_-_5510467 1.137 ENSMUST00000070172.4
Snx32
sorting nexin 32
chr2_-_160872552 1.132 ENSMUST00000103111.2
Zhx3
zinc fingers and homeoboxes 3
chr7_+_28180226 1.128 ENSMUST00000172467.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr7_+_16130285 1.125 ENSMUST00000168693.1
Slc8a2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr18_+_63708689 1.101 ENSMUST00000072726.5
Wdr7
WD repeat domain 7
chr16_-_43979050 1.099 ENSMUST00000165648.1
ENSMUST00000036321.7
Zdhhc23

zinc finger, DHHC domain containing 23

chr11_+_61485431 1.096 ENSMUST00000064783.3
ENSMUST00000040522.6
Mfap4

microfibrillar-associated protein 4

chr12_-_4038905 1.094 ENSMUST00000111178.1
Efr3b
EFR3 homolog B (S. cerevisiae)
chr11_-_69369377 1.094 ENSMUST00000092971.6
ENSMUST00000108661.1
Chd3

chromodomain helicase DNA binding protein 3

chrX_+_161717055 1.092 ENSMUST00000112338.1
Rai2
retinoic acid induced 2
chr7_+_28180272 1.090 ENSMUST00000173223.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr9_+_100643605 1.086 ENSMUST00000041418.6
Stag1
stromal antigen 1
chr1_+_170214826 1.085 ENSMUST00000159201.1
ENSMUST00000055830.1
4930500M09Rik

RIKEN cDNA 4930500M09 gene

chr6_+_135198034 1.083 ENSMUST00000130612.1
8430419L09Rik
RIKEN cDNA 8430419L09 gene
chr5_+_123015010 1.083 ENSMUST00000121652.1
ENSMUST00000051016.4
Orai1

ORAI calcium release-activated calcium modulator 1

chr15_+_100870670 1.079 ENSMUST00000082209.6
Scn8a
sodium channel, voltage-gated, type VIII, alpha
chr8_+_104101625 1.077 ENSMUST00000034339.8
Cdh5
cadherin 5
chr7_+_12881165 1.074 ENSMUST00000144578.1
Zfp128
zinc finger protein 128
chr17_-_45686899 1.068 ENSMUST00000156254.1
Tmem63b
transmembrane protein 63b
chr2_+_133552159 1.067 ENSMUST00000028836.6
Bmp2
bone morphogenetic protein 2
chr2_-_58567157 1.067 ENSMUST00000056376.5
Acvr1
activin A receptor, type 1
chr17_+_87107621 1.065 ENSMUST00000041369.6
Socs5
suppressor of cytokine signaling 5
chr13_+_54575008 1.049 ENSMUST00000026988.4
Arl10
ADP-ribosylation factor-like 10
chr11_-_85139939 1.042 ENSMUST00000108075.2
Usp32
ubiquitin specific peptidase 32
chr2_-_132385435 1.042 ENSMUST00000110156.1
Prokr2
prokineticin receptor 2
chr10_+_88379127 1.033 ENSMUST00000127615.1
Gnptab
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr1_+_15287259 1.030 ENSMUST00000175681.1
Kcnb2
potassium voltage gated channel, Shab-related subfamily, member 2
chr13_-_70637634 1.029 ENSMUST00000043493.5
BC018507
cDNA sequence BC018507
chr12_+_8674391 1.022 ENSMUST00000163569.1
ENSMUST00000169089.1
Pum2

pumilio 2 (Drosophila)

chr2_-_25319095 1.009 ENSMUST00000114318.3
ENSMUST00000114310.3
ENSMUST00000114308.3
ENSMUST00000114317.3
ENSMUST00000028335.6
ENSMUST00000114314.3
ENSMUST00000114307.1
Grin1






glutamate receptor, ionotropic, NMDA1 (zeta 1)






chr10_-_84440591 1.006 ENSMUST00000020220.8
Nuak1
NUAK family, SNF1-like kinase, 1
chr1_+_55406163 1.003 ENSMUST00000042986.8
Plcl1
phospholipase C-like 1
chr7_-_6696423 1.002 ENSMUST00000002336.8
Zim1
zinc finger, imprinted 1
chr4_-_22488296 0.997 ENSMUST00000178174.1
Pou3f2
POU domain, class 3, transcription factor 2
chr5_+_111733924 0.996 ENSMUST00000180627.1
Gm26897
predicted gene, 26897
chr5_-_34288407 0.993 ENSMUST00000114368.1
ENSMUST00000114369.1
Zfyve28

zinc finger, FYVE domain containing 28

chr13_+_81711407 0.993 ENSMUST00000057598.5
Mblac2
metallo-beta-lactamase domain containing 2
chr1_+_37299882 0.991 ENSMUST00000136846.1
ENSMUST00000027287.4
ENSMUST00000132401.1
Inpp4a


inositol polyphosphate-4-phosphatase, type I


chr7_+_131966446 0.988 ENSMUST00000045840.4
Gpr26
G protein-coupled receptor 26
chr15_-_100599983 0.987 ENSMUST00000073837.6
Pou6f1
POU domain, class 6, transcription factor 1
chr10_+_127380799 0.982 ENSMUST00000111628.2
R3hdm2
R3H domain containing 2
chr2_-_5676046 0.977 ENSMUST00000114987.3
Camk1d
calcium/calmodulin-dependent protein kinase ID
chr4_+_43578921 0.960 ENSMUST00000030190.8
Rgp1
RGP1 retrograde golgi transport homolog (S. cerevisiae)
chr11_-_118248507 0.959 ENSMUST00000017276.7
Cyth1
cytohesin 1
chr6_+_52714219 0.956 ENSMUST00000138040.1
ENSMUST00000129660.1
Tax1bp1

Tax1 (human T cell leukemia virus type I) binding protein 1

chr15_+_79108911 0.952 ENSMUST00000040320.8
Micall1
microtubule associated monooxygenase, calponin and LIM domain containing -like 1
chr13_-_59557230 0.939 ENSMUST00000165370.1
ENSMUST00000109830.2
ENSMUST00000022040.6
ENSMUST00000171606.1
ENSMUST00000167096.1
ENSMUST00000166585.1
Agtpbp1





ATP/GTP binding protein 1





chr18_+_35965036 0.926 ENSMUST00000176873.1
ENSMUST00000177432.1
Psd2

pleckstrin and Sec7 domain containing 2

chr9_-_27030010 0.925 ENSMUST00000034470.9
Vps26b
vacuolar protein sorting 26 homolog B (yeast)
chr11_-_35798884 0.922 ENSMUST00000160726.2
Fbll1
fibrillarin-like 1
chr18_-_20896078 0.914 ENSMUST00000025177.6
ENSMUST00000097658.1
Trappc8

trafficking protein particle complex 8

chr11_+_68692097 0.906 ENSMUST00000018887.8
Myh10
myosin, heavy polypeptide 10, non-muscle
chr13_-_49147931 0.901 ENSMUST00000162581.1
ENSMUST00000110097.2
ENSMUST00000049265.8
ENSMUST00000035538.6
ENSMUST00000110096.1
ENSMUST00000091623.3
Wnk2





WNK lysine deficient protein kinase 2





chr1_-_52817503 0.892 ENSMUST00000162576.1
Inpp1
inositol polyphosphate-1-phosphatase
chr1_-_52817643 0.890 ENSMUST00000027271.2
Inpp1
inositol polyphosphate-1-phosphatase
chr6_-_137649211 0.889 ENSMUST00000134630.1
ENSMUST00000058210.6
ENSMUST00000111878.1
Eps8


epidermal growth factor receptor pathway substrate 8


chr14_-_29721835 0.882 ENSMUST00000022567.7
Cacna2d3
calcium channel, voltage-dependent, alpha2/delta subunit 3
chr9_-_119093468 0.882 ENSMUST00000010804.2
Plcd1
phospholipase C, delta 1
chr4_+_31964081 0.880 ENSMUST00000037607.4
ENSMUST00000080933.6
ENSMUST00000108183.1
ENSMUST00000108184.2
Map3k7



mitogen-activated protein kinase kinase kinase 7



chr1_+_156558844 0.866 ENSMUST00000166172.2
ENSMUST00000027888.6
Abl2

v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene)

chr7_-_98361275 0.863 ENSMUST00000094161.4
ENSMUST00000164726.1
ENSMUST00000167405.1
Tsku


tsukushi


chr3_+_95427575 0.862 ENSMUST00000181809.1
Gm4349
predicted gene 4349
chr1_-_136260873 0.860 ENSMUST00000086395.5
Gpr25
G protein-coupled receptor 25
chr9_+_109931774 0.857 ENSMUST00000169851.2
Map4
microtubule-associated protein 4
chr11_+_72796254 0.853 ENSMUST00000069395.5
Zzef1
zinc finger, ZZ-type with EF hand domain 1
chr1_-_165460430 0.852 ENSMUST00000027856.7
Dcaf6
DDB1 and CUL4 associated factor 6
chr1_-_30949756 0.852 ENSMUST00000076587.3
ENSMUST00000027232.7
Ptp4a1

protein tyrosine phosphatase 4a1

chr16_-_91728701 0.852 ENSMUST00000114023.2
ENSMUST00000117644.1
Cryzl1

crystallin, zeta (quinone reductase)-like 1

chr17_-_24689901 0.849 ENSMUST00000007236.4
Syngr3
synaptogyrin 3
chr11_+_117654211 0.826 ENSMUST00000026658.6
Tnrc6c
trinucleotide repeat containing 6C
chr11_+_49794157 0.822 ENSMUST00000020629.4
Gfpt2
glutamine fructose-6-phosphate transaminase 2
chr11_+_113649169 0.801 ENSMUST00000018805.8
Cog1
component of oligomeric golgi complex 1
chr10_-_79874233 0.800 ENSMUST00000166023.1
ENSMUST00000167707.1
ENSMUST00000165601.1
BC005764


cDNA sequence BC005764


chr15_+_65787023 0.799 ENSMUST00000015146.9
ENSMUST00000173858.1
ENSMUST00000172756.1
ENSMUST00000174856.1
Efr3a



EFR3 homolog A (S. cerevisiae)



chrX_+_161717498 0.794 ENSMUST00000061514.7
Rai2
retinoic acid induced 2
chr11_+_68691906 0.783 ENSMUST00000102611.3
Myh10
myosin, heavy polypeptide 10, non-muscle
chrX_+_105120361 0.783 ENSMUST00000033578.5
Magee1
melanoma antigen, family E, 1
chr12_+_14494561 0.780 ENSMUST00000052528.3
Gm9847
predicted pseudogene 9847
chr7_-_31126945 0.778 ENSMUST00000098548.4
Scn1b
sodium channel, voltage-gated, type I, beta
chr5_-_34288318 0.777 ENSMUST00000094868.3
Zfyve28
zinc finger, FYVE domain containing 28
chr1_-_93101854 0.772 ENSMUST00000171796.1
ENSMUST00000171556.1
Kif1a

kinesin family member 1A

chr13_+_56522497 0.772 ENSMUST00000045428.6
Fbxl21
F-box and leucine-rich repeat protein 21
chr7_-_57509995 0.771 ENSMUST00000068456.6
Gabra5
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5
chr9_+_45370185 0.771 ENSMUST00000085939.6
Fxyd6
FXYD domain-containing ion transport regulator 6
chr4_+_139574697 0.767 ENSMUST00000174078.1
Iffo2
intermediate filament family orphan 2
chr2_-_155514796 0.767 ENSMUST00000029131.4
Ggt7
gamma-glutamyltransferase 7
chr11_+_72796164 0.758 ENSMUST00000172220.1
Zzef1
zinc finger, ZZ-type with EF hand domain 1
chr16_+_17561885 0.752 ENSMUST00000171002.1
ENSMUST00000023441.4
P2rx6

purinergic receptor P2X, ligand-gated ion channel, 6

chr19_-_40612160 0.750 ENSMUST00000132452.1
ENSMUST00000135795.1
ENSMUST00000025981.8
Tctn3


tectonic family member 3


chr14_-_76110760 0.748 ENSMUST00000022585.3
Gpalpp1
GPALPP motifs containing 1
chr7_+_141949846 0.748 ENSMUST00000172652.1
Brsk2
BR serine/threonine kinase 2
chr13_-_54611332 0.740 ENSMUST00000091609.4
Cltb
clathrin, light polypeptide (Lcb)
chr2_+_121358591 0.738 ENSMUST00000000317.6
ENSMUST00000129130.1
Ckmt1

creatine kinase, mitochondrial 1, ubiquitous

chr10_-_17947997 0.738 ENSMUST00000037879.6
Heca
headcase homolog (Drosophila)
chr6_+_17463826 0.735 ENSMUST00000140070.1
Met
met proto-oncogene
chr17_+_87672523 0.732 ENSMUST00000172855.1
Msh2
mutS homolog 2 (E. coli)
chr1_-_36445248 0.730 ENSMUST00000125304.1
ENSMUST00000115011.1
Lman2l

lectin, mannose-binding 2-like

chr1_+_105663855 0.724 ENSMUST00000086721.3
ENSMUST00000039173.6
2310035C23Rik

RIKEN cDNA 2310035C23 gene

chr1_+_179668202 0.722 ENSMUST00000040538.3
Sccpdh
saccharopine dehydrogenase (putative)
chr4_-_151108454 0.719 ENSMUST00000105670.1
Camta1
calmodulin binding transcription activator 1
chr12_-_31950210 0.716 ENSMUST00000176084.1
ENSMUST00000176103.1
ENSMUST00000167458.2
Hbp1


high mobility group box transcription factor 1


chr4_-_155398059 0.712 ENSMUST00000030925.2
Gabrd
gamma-aminobutyric acid (GABA) A receptor, subunit delta
chr4_-_143212691 0.712 ENSMUST00000105778.1
ENSMUST00000134791.1
Prdm2

PR domain containing 2, with ZNF domain

chr12_-_31950170 0.710 ENSMUST00000176520.1
Hbp1
high mobility group box transcription factor 1
chr9_+_100643448 0.707 ENSMUST00000146312.1
ENSMUST00000129269.1
Stag1

stromal antigen 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0070650 actin filament bundle distribution(GO:0070650)
1.0 3.9 GO:0060912 cardiac cell fate specification(GO:0060912)
0.9 2.7 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.7 2.8 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.6 3.8 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) phosphate ion transmembrane transport(GO:0035435) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.6 4.2 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.6 2.4 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.6 2.9 GO:1990034 calcium ion export from cell(GO:1990034)
0.5 3.7 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.5 1.6 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.5 1.4 GO:1900673 olefin metabolic process(GO:1900673)
0.5 1.9 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.5 1.4 GO:1902022 L-lysine transport(GO:1902022)
0.4 2.2 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.4 1.7 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.4 1.2 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.4 1.2 GO:0032650 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) interleukin-1 alpha secretion(GO:0050703)
0.4 1.1 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.4 2.6 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.4 6.6 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.4 1.1 GO:0003289 endocardial cushion fusion(GO:0003274) atrial septum primum morphogenesis(GO:0003289)
0.3 1.0 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.3 1.0 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.3 1.3 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.3 0.6 GO:0008355 olfactory learning(GO:0008355)
0.3 1.6 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.3 1.8 GO:0009405 pathogenesis(GO:0009405)
0.3 1.2 GO:0050955 thermoception(GO:0050955)
0.3 2.6 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.3 0.3 GO:2000331 regulation of terminal button organization(GO:2000331)
0.3 1.1 GO:0070970 interleukin-2 secretion(GO:0070970)
0.3 0.8 GO:0086047 membrane depolarization during Purkinje myocyte cell action potential(GO:0086047)
0.3 2.6 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.2 2.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.2 0.7 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.2 0.7 GO:0050975 sensory perception of touch(GO:0050975)
0.2 1.6 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 1.8 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.2 2.9 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.2 2.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.2 0.9 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.2 0.9 GO:0097343 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.2 1.5 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.2 1.0 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.2 2.1 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.2 1.0 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.2 0.8 GO:0006751 glutathione catabolic process(GO:0006751)
0.2 0.6 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.2 1.3 GO:0015808 L-alanine transport(GO:0015808)
0.2 4.9 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2 0.9 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.2 1.1 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.2 0.9 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701) positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.2 1.2 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.2 0.9 GO:0051012 microtubule sliding(GO:0051012)
0.2 0.5 GO:0060268 negative regulation of respiratory burst(GO:0060268)
0.2 0.8 GO:0038026 glycoprotein transport(GO:0034436) reelin-mediated signaling pathway(GO:0038026)
0.2 0.6 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.2 4.4 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 3.9 GO:0046856 phospholipid dephosphorylation(GO:0046839) phosphatidylinositol dephosphorylation(GO:0046856)
0.1 0.4 GO:1990859 cellular response to endothelin(GO:1990859)
0.1 1.0 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.1 0.7 GO:0006817 phosphate ion transport(GO:0006817)
0.1 7.7 GO:0015807 L-amino acid transport(GO:0015807)
0.1 1.0 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.1 0.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.9 GO:0030242 pexophagy(GO:0030242)
0.1 1.1 GO:0071493 elastic fiber assembly(GO:0048251) cellular response to UV-B(GO:0071493)
0.1 3.5 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.1 0.7 GO:0051013 microtubule severing(GO:0051013)
0.1 1.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.2 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 1.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.6 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.1 1.3 GO:0070932 histone H3 deacetylation(GO:0070932)
0.1 0.5 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.1 0.6 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1 1.3 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.1 0.7 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 0.6 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.1 1.5 GO:0051382 kinetochore assembly(GO:0051382)
0.1 0.5 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.1 0.3 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.1 0.4 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 0.3 GO:0032240 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.1 0.3 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.1 1.0 GO:0035635 entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.1 1.7 GO:0021702 cerebellar Purkinje cell differentiation(GO:0021702)
0.1 0.3 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.1 0.5 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.1 0.7 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 0.4 GO:1905247 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.1 0.4 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.1 1.7 GO:0036010 protein localization to endosome(GO:0036010)
0.1 0.3 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.1 0.8 GO:0033280 response to vitamin D(GO:0033280)
0.1 0.2 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.1 0.4 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 1.0 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.1 1.4 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.1 2.0 GO:0043171 peptide catabolic process(GO:0043171)
0.1 1.6 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.1 0.7 GO:0000042 protein targeting to Golgi(GO:0000042)
0.1 0.2 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.1 0.3 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 1.1 GO:0033630 regulation of neuron maturation(GO:0014041) positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.1 0.4 GO:0090394 negative regulation of excitatory postsynaptic potential(GO:0090394)
0.1 0.7 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.1 0.3 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.1 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 0.4 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.1 0.6 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 1.0 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.1 2.5 GO:0007520 myoblast fusion(GO:0007520)
0.1 1.1 GO:0002115 store-operated calcium entry(GO:0002115)
0.1 0.2 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.1 0.2 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.1 0.5 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.1 0.2 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.2 GO:0002536 respiratory burst involved in inflammatory response(GO:0002536)
0.1 0.2 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.1 0.3 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.1 0.3 GO:0007403 glial cell fate determination(GO:0007403)
0.1 0.1 GO:0071211 protein targeting to vacuole involved in autophagy(GO:0071211)
0.1 0.4 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.1 0.4 GO:0007625 grooming behavior(GO:0007625)
0.1 2.3 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.1 1.5 GO:0018345 protein palmitoylation(GO:0018345)
0.1 0.6 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.2 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.1 0.3 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.1 0.5 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 0.2 GO:1902624 positive regulation of granulocyte chemotaxis(GO:0071624) positive regulation of neutrophil chemotaxis(GO:0090023) positive regulation of neutrophil migration(GO:1902624)
0.0 0.1 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0 0.3 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.4 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 0.2 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.1 GO:0035672 transepithelial chloride transport(GO:0030321) oligopeptide transmembrane transport(GO:0035672)
0.0 0.6 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.0 0.2 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.2 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 3.8 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 1.2 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.7 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.5 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.0 0.3 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.7 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.4 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.7 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.3 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.4 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.8 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.2 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.3 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.1 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.8 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.0 0.2 GO:0006561 proline biosynthetic process(GO:0006561)
0.0 0.7 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.2 GO:1905169 protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171)
0.0 0.3 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.3 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.2 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.3 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.1 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.0 0.6 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.8 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.3 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 1.1 GO:0042596 fear response(GO:0042596)
0.0 0.4 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 0.7 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.3 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.7 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 1.1 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.1 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0 1.1 GO:0050905 neuromuscular process(GO:0050905)
0.0 0.2 GO:0001842 neural fold formation(GO:0001842)
0.0 0.2 GO:0030593 neutrophil chemotaxis(GO:0030593) neutrophil migration(GO:1990266)
0.0 0.1 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 0.1 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.3 GO:0061339 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0 1.7 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 1.7 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 0.2 GO:0035878 nail development(GO:0035878)
0.0 0.2 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.6 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 1.2 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.0 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.5 GO:0033198 response to ATP(GO:0033198)
0.0 0.0 GO:0030070 insulin processing(GO:0030070)
0.0 0.2 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.2 GO:0051352 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444)
0.0 0.4 GO:0072673 lamellipodium morphogenesis(GO:0072673)
0.0 1.3 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 0.4 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.2 GO:0048266 behavioral response to pain(GO:0048266)
0.0 1.2 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 1.4 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.0 1.0 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.9 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.4 GO:0035411 catenin import into nucleus(GO:0035411)
0.0 0.7 GO:1901264 carbohydrate derivative transport(GO:1901264)
0.0 0.1 GO:0021747 cochlear nucleus development(GO:0021747) regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 1.0 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.7 GO:0032091 negative regulation of protein binding(GO:0032091)
0.0 0.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.1 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.1 GO:0006544 glycine metabolic process(GO:0006544)
0.0 2.4 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.3 GO:0044804 nucleophagy(GO:0044804)
0.0 0.1 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 0.1 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0098838 reduced folate transmembrane transport(GO:0098838)
0.0 0.3 GO:0030262 cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.0 0.1 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.0 GO:2000744 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.0 0.5 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.0 0.1 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.4 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.0 1.1 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.4 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 1.0 GO:1903363 negative regulation of cellular protein catabolic process(GO:1903363)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.4 GO:0097513 myosin II filament(GO:0097513)
0.5 2.0 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.4 1.1 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
0.4 1.1 GO:0071953 elastic fiber(GO:0071953)
0.4 1.4 GO:0044307 dendritic branch(GO:0044307)
0.4 1.1 GO:0048179 activin receptor complex(GO:0048179)
0.3 3.8 GO:0016600 flotillin complex(GO:0016600)
0.3 0.3 GO:0036125 mitochondrial fatty acid beta-oxidation multienzyme complex(GO:0016507) fatty acid beta-oxidation multienzyme complex(GO:0036125)
0.3 1.7 GO:0044305 calyx of Held(GO:0044305)
0.2 1.8 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.2 2.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.2 0.6 GO:0071920 cleavage body(GO:0071920)
0.2 0.7 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 0.8 GO:0001533 cornified envelope(GO:0001533)
0.2 2.5 GO:0005614 interstitial matrix(GO:0005614)
0.1 2.7 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 1.0 GO:0097422 tubular endosome(GO:0097422)
0.1 0.8 GO:0008091 spectrin(GO:0008091)
0.1 0.9 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 1.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 1.4 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1 0.5 GO:0032280 symmetric synapse(GO:0032280)
0.1 2.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 1.3 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1 1.9 GO:0030008 TRAPP complex(GO:0030008)
0.1 1.6 GO:1990635 proximal dendrite(GO:1990635)
0.1 1.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 1.5 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 0.3 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 0.7 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 1.0 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.4 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 0.3 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.1 2.1 GO:0001891 phagocytic cup(GO:0001891)
0.1 1.2 GO:0017119 Golgi transport complex(GO:0017119)
0.1 0.2 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.1 2.5 GO:0030139 endocytic vesicle(GO:0030139)
0.1 6.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 1.6 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.1 2.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 1.9 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 1.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.4 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.2 GO:0090537 CERF complex(GO:0090537)
0.1 0.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 2.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 0.3 GO:0070820 tertiary granule(GO:0070820)
0.1 1.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 4.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 0.2 GO:0034679 integrin alpha9-beta1 complex(GO:0034679)
0.0 0.6 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.8 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.6 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.8 GO:0030904 retromer complex(GO:0030904)
0.0 0.3 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.2 GO:0072687 meiotic spindle(GO:0072687)
0.0 1.9 GO:0031901 early endosome membrane(GO:0031901)
0.0 5.0 GO:0005903 brush border(GO:0005903)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 2.2 GO:0005811 lipid particle(GO:0005811)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 1.4 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.3 GO:0043196 varicosity(GO:0043196)
0.0 0.3 GO:0042587 glycogen granule(GO:0042587)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.4 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.8 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.3 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0 0.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 1.1 GO:0031941 filamentous actin(GO:0031941)
0.0 5.1 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.2 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.1 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.6 GO:0005921 gap junction(GO:0005921)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 6.7 GO:0014069 postsynaptic density(GO:0014069)
0.0 3.2 GO:0005923 bicellular tight junction(GO:0005923)
0.0 4.1 GO:0008021 synaptic vesicle(GO:0008021)
0.0 1.2 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.9 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 2.4 GO:0005774 vacuolar membrane(GO:0005774)
0.0 0.5 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.4 GO:0008180 COP9 signalosome(GO:0008180)
0.0 2.6 GO:0043209 myelin sheath(GO:0043209)
0.0 2.5 GO:0001650 fibrillar center(GO:0001650)
0.0 0.1 GO:0060076 excitatory synapse(GO:0060076)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.9 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.4 GO:0030027 lamellipodium(GO:0030027)
0.0 0.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.5 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.1 GO:0070382 exocytic vesicle(GO:0070382)
0.0 0.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.4 GO:0015030 Cajal body(GO:0015030)
0.0 0.5 GO:0005882 intermediate filament(GO:0005882)
0.0 0.2 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.4 GO:0009986 cell surface(GO:0009986)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.6 2.3 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.6 3.9 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.6 1.7 GO:0001565 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
0.5 1.6 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.5 1.6 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.4 1.8 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.4 1.3 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.4 1.2 GO:0004936 alpha-adrenergic receptor activity(GO:0004936) epinephrine binding(GO:0051379)
0.4 6.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.4 1.4 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.3 1.0 GO:0005436 sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319)
0.3 1.0 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.3 11.1 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.3 0.8 GO:0034437 very-low-density lipoprotein particle binding(GO:0034189) glycoprotein transporter activity(GO:0034437)
0.3 3.7 GO:0022842 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.3 1.0 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.2 2.0 GO:0043208 glycosphingolipid binding(GO:0043208)
0.2 2.9 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.2 0.7 GO:0032139 guanine/thymine mispair binding(GO:0032137) dinucleotide insertion or deletion binding(GO:0032139) single guanine insertion binding(GO:0032142)
0.2 3.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.2 1.4 GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.2 0.9 GO:0016361 activin receptor activity, type I(GO:0016361)
0.2 4.0 GO:0050811 GABA receptor binding(GO:0050811)
0.2 0.7 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2 3.8 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.2 0.7 GO:0004111 creatine kinase activity(GO:0004111)
0.2 0.7 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.2 0.5 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.2 4.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 0.5 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.2 1.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.2 2.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.2 2.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 4.3 GO:0070064 proline-rich region binding(GO:0070064)
0.2 1.1 GO:0019211 phosphatase activator activity(GO:0019211)
0.2 0.6 GO:0035473 lipase binding(GO:0035473)
0.1 0.6 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739) tubulin deacetylase activity(GO:0042903)
0.1 1.3 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 1.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 0.8 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 1.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 1.4 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.6 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 0.8 GO:0086006 sodium channel inhibitor activity(GO:0019871) voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.8 GO:0008242 omega peptidase activity(GO:0008242)
0.1 1.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.6 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 0.6 GO:0045545 syndecan binding(GO:0045545)
0.1 0.4 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 1.4 GO:0015643 toxic substance binding(GO:0015643)
0.1 1.5 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 1.8 GO:0070300 phosphatidic acid binding(GO:0070300)
0.1 2.1 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.7 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.6 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.4 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 2.0 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.4 GO:0034056 estrogen response element binding(GO:0034056)
0.1 0.9 GO:0000182 rDNA binding(GO:0000182)
0.1 2.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 0.3 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.9 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.1 0.2 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.1 0.6 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 0.4 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 1.1 GO:0005248 voltage-gated sodium channel activity(GO:0005248)
0.1 0.3 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.1 0.2 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 0.1 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 0.6 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.1 0.8 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 1.8 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 1.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.3 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.1 0.6 GO:0008301 DNA binding, bending(GO:0008301)
0.1 0.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.4 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.1 0.8 GO:0008483 transaminase activity(GO:0008483)
0.1 0.3 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 0.6 GO:0035325 Toll-like receptor binding(GO:0035325)
0.1 0.9 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.1 0.3 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.5 GO:0016004 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.1 0.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 1.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 2.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 2.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.7 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.2 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 1.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.3 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 1.1 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.3 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 1.3 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.8 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.7 GO:0035497 cAMP response element binding(GO:0035497)
0.0 1.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.2 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:2001069 glycogen binding(GO:2001069)
0.0 0.3 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.7 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.5 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 1.3 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.9 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.6 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.3 GO:0043495 protein anchor(GO:0043495)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.9 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.2 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.5 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215) organophosphate ester transmembrane transporter activity(GO:0015605)
0.0 0.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 4.1 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.7 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.2 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.9 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 1.5 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.2 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.3 GO:0004407 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.0 0.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.7 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.6 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.7 GO:1901505 carbohydrate derivative transporter activity(GO:1901505)
0.0 0.6 GO:0008374 O-acyltransferase activity(GO:0008374)
0.0 0.7 GO:0005230 extracellular ligand-gated ion channel activity(GO:0005230)
0.0 0.3 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.5 GO:0016866 intramolecular transferase activity(GO:0016866)
0.0 0.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.9 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 3.3 GO:0008017 microtubule binding(GO:0008017)
0.0 0.1 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 1.1 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.1 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.9 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.0 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.0 1.4 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 1.4 GO:0017124 SH3 domain binding(GO:0017124)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.0 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 13.2 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.1 2.9 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 1.0 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.1 3.2 SIG_IL4RECEPTOR_IN_B_LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.1 1.1 PID_ALK2_PATHWAY ALK2 signaling events
0.1 1.3 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.1 1.6 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.1 0.9 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 1.1 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.1 5.0 PID_ERBB1_DOWNSTREAM_PATHWAY ErbB1 downstream signaling
0.1 3.1 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 2.1 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 1.5 PID_ARF_3PATHWAY Arf1 pathway
0.1 0.3 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 1.5 PID_PI3KCI_PATHWAY Class I PI3K signaling events
0.0 1.6 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.6 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 1.1 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 0.3 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 1.1 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.3 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.7 ST_B_CELL_ANTIGEN_RECEPTOR B Cell Antigen Receptor
0.0 1.1 PID_CD8_TCR_PATHWAY TCR signaling in naïve CD8+ T cells
0.0 1.1 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 0.9 PID_SHP2_PATHWAY SHP2 signaling
0.0 0.8 PID_INSULIN_PATHWAY Insulin Pathway
0.0 0.5 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 0.2 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.4 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 1.0 PID_BMP_PATHWAY BMP receptor signaling
0.0 1.3 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.4 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 0.6 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.2 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 1.0 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 0.2 ST_GAQ_PATHWAY G alpha q Pathway
0.0 0.5 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 0.2 PID_ARF6_PATHWAY Arf6 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.3 2.4 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.3 3.8 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.3 3.5 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.2 8.8 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.2 4.3 REACTOME_P38MAPK_EVENTS Genes involved in p38MAPK events
0.2 1.2 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.2 0.5 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
0.2 6.5 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 1.5 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 2.6 REACTOME_SOS_MEDIATED_SIGNALLING Genes involved in SOS-mediated signalling
0.1 5.0 REACTOME_CA_DEPENDENT_EVENTS Genes involved in Ca-dependent events
0.1 3.7 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.1 2.0 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 0.9 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 1.4 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.1 3.4 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 2.7 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.4 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 1.6 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.1 0.6 REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS Genes involved in Prolonged ERK activation events
0.1 1.4 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.1 2.1 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.1 0.4 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 0.9 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 0.7 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.2 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.8 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.0 1.3 REACTOME_KINESINS Genes involved in Kinesins
0.0 3.3 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.7 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 1.0 REACTOME_REGULATORY_RNA_PATHWAYS Genes involved in Regulatory RNA pathways
0.0 2.7 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.1 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 1.1 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.8 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.7 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.2 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.1 REACTOME_ABORTIVE_ELONGATION_OF_HIV1_TRANSCRIPT_IN_THE_ABSENCE_OF_TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 0.9 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.8 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 0.8 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.3 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.3 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.4 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.3 REACTOME_MRNA_CAPPING Genes involved in mRNA Capping
0.0 0.5 REACTOME_CTLA4_INHIBITORY_SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 1.7 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.2 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.2 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.4 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.6 REACTOME_IL1_SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.3 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.4 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.5 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.4 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.4 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.2 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.6 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.2 REACTOME_KERATAN_SULFATE_BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.2 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.4 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.2 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.2 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)