Motif ID: Rbpj

Z-value: 1.008


Transcription factors associated with Rbpj:

Gene SymbolEntrez IDGene Name
Rbpj ENSMUSG00000039191.6 Rbpj

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rbpjmm10_v2_chr5_+_53590215_53590351-0.019.6e-01Click!


Activity profile for motif Rbpj.

activity profile for motif Rbpj


Sorted Z-values histogram for motif Rbpj

Sorted Z-values for motif Rbpj



Network of associatons between targets according to the STRING database.



First level regulatory network of Rbpj

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_154960915 16.242 ENSMUST00000049621.6
Hes5
hairy and enhancer of split 5 (Drosophila)
chr11_+_78324200 13.195 ENSMUST00000102478.3
Aldoc
aldolase C, fructose-bisphosphate
chr10_-_30842765 8.447 ENSMUST00000019924.8
Hey2
hairy/enhancer-of-split related with YRPW motif 2
chr4_+_156203292 5.896 ENSMUST00000105140.2
AW011738
expressed sequence AW011738
chr6_-_5298455 5.008 ENSMUST00000057792.8
Pon2
paraoxonase 2
chr2_+_59612034 4.614 ENSMUST00000112568.1
ENSMUST00000037526.4
Tanc1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr11_-_102579461 4.570 ENSMUST00000107081.1
Gm11627
predicted gene 11627
chr2_+_37776229 4.299 ENSMUST00000050372.7
Crb2
crumbs homolog 2 (Drosophila)
chr11_+_101627942 3.649 ENSMUST00000010506.3
Rdm1
RAD52 motif 1
chr2_+_105668935 3.384 ENSMUST00000142772.1
Pax6
paired box gene 6
chr2_+_105668888 3.298 ENSMUST00000111086.4
ENSMUST00000111087.3
Pax6

paired box gene 6

chr5_+_136919137 3.295 ENSMUST00000181045.1
4933404O12Rik
RIKEN cDNA 4933404O12 gene
chrX_+_139684980 3.284 ENSMUST00000096313.3
Tbc1d8b
TBC1 domain family, member 8B
chr19_+_53140430 3.155 ENSMUST00000111741.2
Add3
adducin 3 (gamma)
chr12_-_80260091 2.678 ENSMUST00000167327.1
Actn1
actinin, alpha 1
chr5_-_77115145 2.545 ENSMUST00000081964.5
Hopx
HOP homeobox
chr6_+_29694204 2.473 ENSMUST00000046750.7
ENSMUST00000115250.3
Tspan33

tetraspanin 33

chr9_-_26806384 2.277 ENSMUST00000162702.1
ENSMUST00000040398.7
ENSMUST00000066560.6
Glb1l2


galactosidase, beta 1-like 2


chr12_-_80260356 2.206 ENSMUST00000021554.8
Actn1
actinin, alpha 1
chr2_-_26140468 2.031 ENSMUST00000133808.1
C330006A16Rik
RIKEN cDNA C330006A16 gene
chr9_+_123478693 2.014 ENSMUST00000026269.2
Limd1
LIM domains containing 1
chr1_-_191575534 1.958 ENSMUST00000027933.5
Dtl
denticleless homolog (Drosophila)
chr15_-_86033777 1.845 ENSMUST00000016172.7
Celsr1
cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chr7_+_45216671 1.837 ENSMUST00000134420.1
Tead2
TEA domain family member 2
chr4_-_11007635 1.737 ENSMUST00000054776.3
Plekhf2
pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr7_+_44748584 1.731 ENSMUST00000171821.1
Vrk3
vaccinia related kinase 3
chr7_+_44748413 1.674 ENSMUST00000002275.8
Vrk3
vaccinia related kinase 3
chr12_+_82170016 1.637 ENSMUST00000166429.1
Sipa1l1
signal-induced proliferation-associated 1 like 1
chr7_+_44748640 1.591 ENSMUST00000165957.1
ENSMUST00000144515.2
Vrk3

vaccinia related kinase 3

chr4_+_107830958 1.582 ENSMUST00000106731.2
Lrp8
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr6_+_55203381 1.526 ENSMUST00000053094.7
Fam188b
family with sequence similarity 188, member B
chr18_+_34625009 1.525 ENSMUST00000166044.1
Kif20a
kinesin family member 20A
chr2_-_69586021 1.513 ENSMUST00000100051.2
ENSMUST00000092551.4
ENSMUST00000080953.5
Lrp2


low density lipoprotein receptor-related protein 2


chr19_+_46056539 1.510 ENSMUST00000111899.1
ENSMUST00000099392.3
ENSMUST00000062322.4
Pprc1


peroxisome proliferative activated receptor, gamma, coactivator-related 1


chr2_+_133552159 1.493 ENSMUST00000028836.6
Bmp2
bone morphogenetic protein 2
chr11_+_63133068 1.359 ENSMUST00000108700.1
Pmp22
peripheral myelin protein 22
chr5_-_138172383 1.352 ENSMUST00000000505.9
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr7_+_122159422 1.340 ENSMUST00000033154.6
Plk1
polo-like kinase 1
chr10_+_29313227 1.307 ENSMUST00000161605.1
Echdc1
enoyl Coenzyme A hydratase domain containing 1
chr9_-_55512156 1.170 ENSMUST00000034866.8
Etfa
electron transferring flavoprotein, alpha polypeptide
chr14_+_75131499 1.136 ENSMUST00000125833.1
ENSMUST00000124499.1
Lcp1

lymphocyte cytosolic protein 1

chr5_-_75978447 1.135 ENSMUST00000113516.1
Kdr
kinase insert domain protein receptor
chr11_+_109485606 1.134 ENSMUST00000106697.1
Arsg
arylsulfatase G
chr15_+_83563571 1.123 ENSMUST00000047419.6
Tspo
translocator protein
chr6_+_48593883 1.058 ENSMUST00000154010.1
ENSMUST00000163452.1
ENSMUST00000118229.1
ENSMUST00000009420.8
Repin1



replication initiator 1



chr15_-_75894474 1.030 ENSMUST00000023237.6
Naprt1
nicotinate phosphoribosyltransferase domain containing 1
chr7_-_44670820 0.977 ENSMUST00000048102.7
Myh14
myosin, heavy polypeptide 14
chr18_+_34624621 0.971 ENSMUST00000167161.1
Kif20a
kinesin family member 20A
chr5_+_115327125 0.941 ENSMUST00000031513.7
Srsf9
serine/arginine-rich splicing factor 9
chr15_-_81858317 0.901 ENSMUST00000050467.7
Tob2
transducer of ERBB2, 2
chr7_+_29983948 0.900 ENSMUST00000148442.1
Zfp568
zinc finger protein 568
chr3_-_89270489 0.886 ENSMUST00000107460.1
ENSMUST00000029565.4
ENSMUST00000130230.1
Slc50a1


solute carrier family 50 (sugar transporter), member 1


chr7_-_105752193 0.879 ENSMUST00000033184.4
Tpp1
tripeptidyl peptidase I
chr11_-_80779989 0.867 ENSMUST00000041065.7
ENSMUST00000070997.5
Myo1d

myosin ID

chr9_-_13446753 0.854 ENSMUST00000167906.2
Gm17571
predicted gene, 17571
chrX_+_99136119 0.832 ENSMUST00000052839.6
Efnb1
ephrin B1
chr2_+_164746028 0.832 ENSMUST00000109327.3
Dnttip1
deoxynucleotidyltransferase, terminal, interacting protein 1
chr5_+_33658550 0.831 ENSMUST00000152847.1
Tacc3
transforming, acidic coiled-coil containing protein 3
chr13_+_12395362 0.820 ENSMUST00000059270.8
Heatr1
HEAT repeat containing 1
chrX_-_160138375 0.813 ENSMUST00000033662.8
Pdha1
pyruvate dehydrogenase E1 alpha 1
chr13_-_54590047 0.763 ENSMUST00000148222.1
ENSMUST00000026987.5
Nop16

NOP16 nucleolar protein

chr5_-_24577467 0.759 ENSMUST00000030795.8
Abcf2
ATP-binding cassette, sub-family F (GCN20), member 2
chr5_-_138171813 0.735 ENSMUST00000155902.1
ENSMUST00000148879.1
Mcm7

minichromosome maintenance deficient 7 (S. cerevisiae)

chr17_+_35121455 0.732 ENSMUST00000173380.1
ENSMUST00000173043.3
ENSMUST00000165306.2
Gpank1


G patch domain and ankyrin repeats 1


chrX_-_134600976 0.728 ENSMUST00000033621.6
Gla
galactosidase, alpha
chr4_-_107178282 0.711 ENSMUST00000058585.7
Tceanc2
transcription elongation factor A (SII) N-terminal and central domain containing 2
chr2_+_164745979 0.680 ENSMUST00000017443.7
ENSMUST00000109326.3
Dnttip1

deoxynucleotidyltransferase, terminal, interacting protein 1

chr1_+_87327044 0.668 ENSMUST00000173173.1
Gigyf2
GRB10 interacting GYF protein 2
chr3_-_103809278 0.664 ENSMUST00000063502.6
ENSMUST00000106832.1
ENSMUST00000106834.1
ENSMUST00000029435.8
Dclre1b



DNA cross-link repair 1B, PSO2 homolog (S. cerevisiae)



chr7_+_16842896 0.656 ENSMUST00000168093.2
Prkd2
protein kinase D2
chr9_-_114640175 0.643 ENSMUST00000070117.6
Cnot10
CCR4-NOT transcription complex, subunit 10
chr7_-_24208093 0.631 ENSMUST00000086006.5
Zfp111
zinc finger protein 111
chr12_-_112673944 0.629 ENSMUST00000130342.1
Akt1
thymoma viral proto-oncogene 1
chr7_+_45639964 0.610 ENSMUST00000148532.1
Mamstr
MEF2 activating motif and SAP domain containing transcriptional regulator
chr8_-_69974367 0.584 ENSMUST00000116463.2
Gatad2a
GATA zinc finger domain containing 2A
chr3_+_26331150 0.569 ENSMUST00000099182.2
A830092H15Rik
RIKEN cDNA A830092H15 gene
chr4_-_126202583 0.564 ENSMUST00000106142.1
ENSMUST00000169403.1
ENSMUST00000130334.1
Thrap3


thyroid hormone receptor associated protein 3


chr12_-_73047179 0.560 ENSMUST00000050029.7
Six1
sine oculis-related homeobox 1
chr14_-_66124482 0.541 ENSMUST00000070515.1
Ephx2
epoxide hydrolase 2, cytoplasmic
chr19_-_41933276 0.537 ENSMUST00000075280.4
ENSMUST00000112123.2
Exosc1

exosome component 1

chr12_-_4477138 0.531 ENSMUST00000085814.3
Ncoa1
nuclear receptor coactivator 1
chr7_+_112225856 0.525 ENSMUST00000050149.5
ENSMUST00000106647.1
ENSMUST00000106648.1
Mical2


microtubule associated monooxygenase, calponin and LIM domain containing 2


chr7_+_79273201 0.510 ENSMUST00000037315.6
Abhd2
abhydrolase domain containing 2
chr2_-_54085542 0.509 ENSMUST00000100089.2
Rprm
reprimo, TP53 dependent G2 arrest mediator candidate
chr4_-_156197479 0.497 ENSMUST00000075787.6
ENSMUST00000180572.1
Agrn

agrin

chr6_+_50110186 0.470 ENSMUST00000166318.1
ENSMUST00000036236.8
ENSMUST00000036225.8
Mpp6


membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)


chr10_-_81266906 0.464 ENSMUST00000046114.4
Mrpl54
mitochondrial ribosomal protein L54
chr2_+_120609383 0.463 ENSMUST00000124187.1
Haus2
HAUS augmin-like complex, subunit 2
chr7_+_127777376 0.441 ENSMUST00000126761.1
ENSMUST00000047157.6
Setd1a

SET domain containing 1A

chrX_+_7579666 0.436 ENSMUST00000115740.1
ENSMUST00000115739.1
Foxp3

forkhead box P3

chr4_-_126202335 0.435 ENSMUST00000142125.1
ENSMUST00000106141.2
Thrap3

thyroid hormone receptor associated protein 3

chr2_+_92184106 0.424 ENSMUST00000111294.1
ENSMUST00000111293.2
ENSMUST00000162146.1
ENSMUST00000111292.1
ENSMUST00000162497.1
Phf21a




PHD finger protein 21A




chr4_-_149166686 0.420 ENSMUST00000084124.6
Pgd
phosphogluconate dehydrogenase
chr19_-_10577362 0.418 ENSMUST00000025568.2
Tmem138
transmembrane protein 138
chr13_-_67484225 0.413 ENSMUST00000019572.7
Zfp874b
zinc finger protein 874b
chr12_+_83688123 0.394 ENSMUST00000041806.5
Psen1
presenilin 1
chr12_+_8973892 0.386 ENSMUST00000085745.6
ENSMUST00000111113.2
Wdr35

WD repeat domain 35

chr9_+_35559460 0.362 ENSMUST00000034615.3
ENSMUST00000121246.1
Pus3

pseudouridine synthase 3

chr7_+_5020561 0.359 ENSMUST00000085427.3
Zfp865
zinc finger protein 865
chr19_-_10101501 0.359 ENSMUST00000025567.7
Fads2
fatty acid desaturase 2
chr19_+_8967031 0.350 ENSMUST00000052248.7
Eef1g
eukaryotic translation elongation factor 1 gamma
chr1_+_191575721 0.347 ENSMUST00000045450.5
Ints7
integrator complex subunit 7
chr7_+_5020376 0.315 ENSMUST00000076251.4
Zfp865
zinc finger protein 865
chr8_+_110721462 0.273 ENSMUST00000052457.8
Mtss1l
metastasis suppressor 1-like
chr3_+_131564768 0.264 ENSMUST00000029666.9
Papss1
3'-phosphoadenosine 5'-phosphosulfate synthase 1
chr5_+_130257029 0.264 ENSMUST00000100662.3
ENSMUST00000040213.6
Tyw1

tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)

chr11_-_6626030 0.253 ENSMUST00000000394.7
ENSMUST00000136682.1
Tbrg4

transforming growth factor beta regulated gene 4

chr7_-_44748306 0.250 ENSMUST00000118162.1
ENSMUST00000140599.2
ENSMUST00000120798.1
Zfp473


zinc finger protein 473


chr10_+_79704478 0.249 ENSMUST00000179781.1
Bsg
basigin
chr19_+_10577439 0.244 ENSMUST00000168445.1
Cyb561a3
cytochrome b561 family, member A3
chr7_+_29768552 0.242 ENSMUST00000032802.4
Zfp84
zinc finger protein 84
chr2_-_167062607 0.238 ENSMUST00000128676.1
Znfx1
zinc finger, NFX1-type containing 1
chr9_+_64811313 0.232 ENSMUST00000038890.5
Dennd4a
DENN/MADD domain containing 4A
chr7_-_100121512 0.230 ENSMUST00000032969.7
Pold3
polymerase (DNA-directed), delta 3, accessory subunit
chr5_-_90223923 0.223 ENSMUST00000118816.1
ENSMUST00000048363.7
Cox18

cytochrome c oxidase assembly protein 18

chr12_+_33315393 0.218 ENSMUST00000154742.1
Atxn7l1
ataxin 7-like 1
chr10_+_79704499 0.218 ENSMUST00000067036.5
ENSMUST00000178383.1
Bsg

basigin

chr17_+_34205100 0.217 ENSMUST00000131105.1
Tap2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr6_+_117841258 0.209 ENSMUST00000136889.1
ENSMUST00000134526.1
ENSMUST00000112860.1
ENSMUST00000112858.1
Zfp637



zinc finger protein 637



chrX_-_73966329 0.206 ENSMUST00000114372.2
ENSMUST00000033761.6
Hcfc1

host cell factor C1

chr7_-_126649556 0.198 ENSMUST00000084587.1
2510046G10Rik
RIKEN cDNA 2510046G10 gene
chr1_+_87327008 0.187 ENSMUST00000172794.1
ENSMUST00000164992.2
Gigyf2

GRB10 interacting GYF protein 2

chr2_+_26581050 0.184 ENSMUST00000166920.2
Egfl7
EGF-like domain 7
chrX_+_100494291 0.181 ENSMUST00000033570.5
Igbp1
immunoglobulin (CD79A) binding protein 1
chr4_-_126202757 0.176 ENSMUST00000080919.5
Thrap3
thyroid hormone receptor associated protein 3
chr11_-_62457772 0.171 ENSMUST00000127471.2
Ncor1
nuclear receptor co-repressor 1
chr19_-_6992478 0.169 ENSMUST00000025915.5
Dnajc4
DnaJ (Hsp40) homolog, subfamily C, member 4
chr6_+_21949571 0.165 ENSMUST00000031680.3
ENSMUST00000115389.1
ENSMUST00000151473.1
Ing3


inhibitor of growth family, member 3


chr12_-_36382181 0.163 ENSMUST00000171007.1
D630036H23Rik
RIKEN cDNA D630036H23 gene
chr16_+_33062512 0.115 ENSMUST00000023497.2
Lmln
leishmanolysin-like (metallopeptidase M8 family)
chr9_+_106821874 0.110 ENSMUST00000159645.1
Vprbp
Vpr (HIV-1) binding protein
chr16_-_17722879 0.092 ENSMUST00000080936.6
ENSMUST00000012259.7
Med15

mediator complex subunit 15

chr7_+_127967457 0.090 ENSMUST00000106251.3
ENSMUST00000077609.5
ENSMUST00000121616.2
Fus


fused in sarcoma


chr14_-_55722223 0.078 ENSMUST00000163889.1
Rabggta
Rab geranylgeranyl transferase, a subunit
chr6_+_91473695 0.066 ENSMUST00000032183.4
Tmem43
transmembrane protein 43
chr10_-_62726086 0.061 ENSMUST00000133371.1
Stox1
storkhead box 1
chr7_-_25237849 0.055 ENSMUST00000071739.5
ENSMUST00000108411.1
Gsk3a

glycogen synthase kinase 3 alpha

chr2_+_167062934 0.054 ENSMUST00000125674.1
1500012F01Rik
RIKEN cDNA 1500012F01 gene
chr13_-_67609617 0.051 ENSMUST00000138725.1
AA987161
expressed sequence AA987161
chr2_-_120609500 0.033 ENSMUST00000133612.1
ENSMUST00000102498.1
ENSMUST00000102499.1
Lrrc57


leucine rich repeat containing 57


chr9_+_44334685 0.033 ENSMUST00000052686.2
H2afx
H2A histone family, member X
chr2_-_120609319 0.016 ENSMUST00000102497.3
Lrrc57
leucine rich repeat containing 57
chr5_+_148959263 0.015 ENSMUST00000135240.1
Gm15409
predicted gene 15409
chr2_-_120609283 0.015 ENSMUST00000102496.1
Lrrc57
leucine rich repeat containing 57
chr9_-_103222063 0.007 ENSMUST00000170904.1
Trf
transferrin

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 16.2 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
2.8 8.4 GO:0003195 tricuspid valve formation(GO:0003195) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
1.3 6.7 GO:0021905 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
1.3 13.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.9 2.7 GO:0014028 notochord formation(GO:0014028)
0.6 1.8 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.5 1.5 GO:0060129 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.4 2.5 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.4 1.1 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.3 5.1 GO:0051639 actin filament network formation(GO:0051639)
0.3 1.3 GO:0040038 polar body extrusion after meiotic divisions(GO:0040038)
0.3 0.9 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.3 2.0 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.3 5.0 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.2 2.3 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.2 2.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.2 0.5 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) olefin metabolic process(GO:1900673)
0.2 4.6 GO:0097062 dendritic spine maintenance(GO:0097062)
0.2 1.6 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.2 0.6 GO:0060709 glycogen cell differentiation involved in embryonic placenta development(GO:0060709)
0.2 2.0 GO:0019985 translesion synthesis(GO:0019985)
0.1 0.6 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.1 0.4 GO:0032829 positive regulation of T cell anergy(GO:0002669) negative regulation of T cell cytokine production(GO:0002725) positive regulation of lymphocyte anergy(GO:0002913) regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 0.4 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.1 2.5 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.1 0.8 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 0.7 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.8 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 0.5 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 1.0 GO:0032570 response to progesterone(GO:0032570)
0.1 0.7 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 0.7 GO:0046477 glycosylceramide catabolic process(GO:0046477) negative regulation of nitric-oxide synthase activity(GO:0051001)
0.1 1.5 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.1 0.3 GO:0034035 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.1 1.8 GO:0030903 notochord development(GO:0030903)
0.1 0.4 GO:0015871 astrocyte activation involved in immune response(GO:0002265) choline transport(GO:0015871)
0.1 0.2 GO:0002489 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589)
0.1 1.3 GO:0032060 bleb assembly(GO:0032060)
0.1 0.2 GO:0019046 release from viral latency(GO:0019046)
0.1 0.9 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.1 1.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 0.4 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 0.8 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 2.5 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 0.1 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.1 0.9 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 1.2 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 1.1 GO:2001273 regulation of glucose import in response to insulin stimulus(GO:2001273)
0.0 3.3 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.4 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 0.2 GO:0051204 protein insertion into mitochondrial membrane(GO:0051204)
0.0 5.0 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.4 GO:0045019 negative regulation of nitric oxide biosynthetic process(GO:0045019) negative regulation of nitric oxide metabolic process(GO:1904406)
0.0 1.0 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.2 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 0.7 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.0 0.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.9 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.9 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.3 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.6 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.4 GO:0001967 suckling behavior(GO:0001967)
0.0 0.9 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 3.2 GO:0042493 response to drug(GO:0042493)
0.0 0.1 GO:0071500 cellular response to nitrosative stress(GO:0071500)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.9 GO:0032127 dense core granule membrane(GO:0032127)
0.6 1.8 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.4 8.2 GO:0016580 Sin3 complex(GO:0016580)
0.3 1.3 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.3 1.2 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.3 2.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.3 2.5 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 1.1 GO:0097443 sorting endosome(GO:0097443)
0.2 1.0 GO:0097513 myosin II filament(GO:0097513)
0.2 2.0 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 2.1 GO:0042555 MCM complex(GO:0042555)
0.1 0.8 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 0.5 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 0.5 GO:0070652 HAUS complex(GO:0070652)
0.1 1.4 GO:0043218 compact myelin(GO:0043218)
0.0 0.5 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.7 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.4 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.6 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 5.5 GO:0005903 brush border(GO:0005903)
0.0 2.5 GO:0005871 kinesin complex(GO:0005871)
0.0 0.5 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.4 GO:0035253 ciliary rootlet(GO:0035253)
0.0 1.2 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 2.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.2 GO:0042825 TAP complex(GO:0042825)
0.0 0.1 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 19.2 GO:0030424 axon(GO:0030424)
0.0 0.8 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.5 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 4.3 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.2 GO:0005811 lipid particle(GO:0005811)
0.0 6.4 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 6.2 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 1.6 GO:0043197 dendritic spine(GO:0043197)
0.0 1.1 GO:0019867 mitochondrial outer membrane(GO:0005741) outer membrane(GO:0019867) organelle outer membrane(GO:0031968)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 8.4 GO:0035939 microsatellite binding(GO:0035939)
2.2 13.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
1.3 5.0 GO:0004064 arylesterase activity(GO:0004064)
0.9 4.3 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.5 1.5 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.5 2.3 GO:0004565 beta-galactosidase activity(GO:0004565)
0.4 6.7 GO:0003680 AT DNA binding(GO:0003680)
0.4 1.6 GO:0038025 reelin receptor activity(GO:0038025)
0.4 0.7 GO:0015925 galactosidase activity(GO:0015925)
0.3 0.9 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.3 4.9 GO:0017166 vinculin binding(GO:0017166)
0.2 1.1 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.2 1.3 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.2 0.9 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.2 1.5 GO:0019211 phosphatase activator activity(GO:0019211)
0.2 0.8 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 0.4 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 1.8 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.4 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.5 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 1.8 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.1 0.5 GO:0033142 progesterone receptor binding(GO:0033142)
0.1 0.4 GO:1990188 euchromatin binding(GO:1990188)
0.1 16.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 0.5 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 1.1 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 0.7 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 0.4 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768)
0.1 0.9 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 0.2 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.1 4.4 GO:0005080 protein kinase C binding(GO:0005080)
0.1 2.1 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.4 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.5 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 1.0 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 1.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.5 GO:0005537 mannose binding(GO:0005537)
0.0 2.5 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.3 GO:0010181 FMN binding(GO:0010181)
0.0 0.7 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 5.2 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 0.8 GO:0030515 snoRNA binding(GO:0030515)
0.0 1.2 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.0 0.9 GO:0051119 sugar transmembrane transporter activity(GO:0051119)
0.0 0.6 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.5 GO:0071949 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) FAD binding(GO:0071949)
0.0 0.2 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 1.1 GO:0042562 hormone binding(GO:0042562)
0.0 1.5 GO:0031491 nucleosome binding(GO:0031491)
0.0 3.4 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.3 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 2.0 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.3 GO:0003785 actin monomer binding(GO:0003785)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 22.0 PID_CDC42_PATHWAY CDC42 signaling events
0.2 9.9 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.2 4.9 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.1 0.9 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.1 2.1 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.1 3.4 PID_ATR_PATHWAY ATR signaling pathway
0.1 2.5 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 1.6 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.8 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 1.5 PID_BMP_PATHWAY BMP receptor signaling
0.0 0.8 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 0.4 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 0.6 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 6.7 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.3 13.2 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.3 24.5 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.2 4.9 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.1 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 2.1 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.1 1.5 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.1 1.1 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 1.6 REACTOME_PLATELET_SENSITIZATION_BY_LDL Genes involved in Platelet sensitization by LDL
0.1 2.5 REACTOME_KINESINS Genes involved in Kinesins
0.1 2.4 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 1.3 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 1.2 REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 0.8 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.5 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 0.5 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism
0.0 2.7 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.3 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.0 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.6 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.2 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.5 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.0 0.9 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.4 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.9 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.2 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC