Motif ID: Alx4

Z-value: 0.567


Transcription factors associated with Alx4:

Gene SymbolEntrez IDGene Name
Alx4 ENSMUSG00000040310.6 Alx4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Alx4mm10_v2_chr2_+_93642307_93642388-0.143.9e-01Click!


Activity profile for motif Alx4.

activity profile for motif Alx4


Sorted Z-values histogram for motif Alx4

Sorted Z-values for motif Alx4



Network of associatons between targets according to the STRING database.



First level regulatory network of Alx4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_97479470 2.618 ENSMUST00000105287.3
Dcn
decorin
chr6_-_136875794 1.930 ENSMUST00000032342.1
Mgp
matrix Gla protein
chr13_-_81710937 1.791 ENSMUST00000161920.1
ENSMUST00000048993.5
Polr3g

polymerase (RNA) III (DNA directed) polypeptide G

chr13_+_44121167 1.750 ENSMUST00000163056.1
ENSMUST00000159595.1
Gm5083

predicted gene 5083

chrM_+_2743 1.689 ENSMUST00000082392.1
mt-Nd1
mitochondrially encoded NADH dehydrogenase 1
chr15_+_9436028 1.597 ENSMUST00000042360.3
Capsl
calcyphosine-like
chr7_-_45103747 1.586 ENSMUST00000003512.7
Fcgrt
Fc receptor, IgG, alpha chain transporter
chrM_+_9452 1.547 ENSMUST00000082411.1
mt-Nd3
mitochondrially encoded NADH dehydrogenase 3
chrX_-_134111852 1.512 ENSMUST00000033610.6
Nox1
NADPH oxidase 1
chr1_-_163725123 1.451 ENSMUST00000159679.1
Mettl11b
methyltransferase like 11B
chr8_+_23411490 1.357 ENSMUST00000033952.7
Sfrp1
secreted frizzled-related protein 1
chr7_-_46667375 1.349 ENSMUST00000107669.2
Tph1
tryptophan hydroxylase 1
chrX_+_73483602 1.338 ENSMUST00000033741.8
ENSMUST00000169489.1
Bgn

biglycan

chr2_+_91257323 1.287 ENSMUST00000111349.2
ENSMUST00000131711.1
Pacsin3

protein kinase C and casein kinase substrate in neurons 3

chr19_+_55895508 1.271 ENSMUST00000111646.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chrM_+_10167 1.202 ENSMUST00000082414.1
mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr8_+_94152607 1.170 ENSMUST00000034211.8
Mt3
metallothionein 3
chr10_-_37138863 1.106 ENSMUST00000092584.5
Marcks
myristoylated alanine rich protein kinase C substrate
chr1_-_152386675 1.084 ENSMUST00000015124.8
Tsen15
tRNA splicing endonuclease 15 homolog (S. cerevisiae)
chr2_-_160619971 1.072 ENSMUST00000109473.1
Gm14221
predicted gene 14221
chr9_+_123366921 1.067 ENSMUST00000038863.7
Lars2
leucyl-tRNA synthetase, mitochondrial
chr9_-_123678873 1.032 ENSMUST00000040960.6
Slc6a20a
solute carrier family 6 (neurotransmitter transporter), member 20A
chr1_-_152386589 1.026 ENSMUST00000162371.1
Tsen15
tRNA splicing endonuclease 15 homolog (S. cerevisiae)
chr13_+_104229366 1.016 ENSMUST00000022227.6
Cenpk
centromere protein K
chr14_-_66124482 1.002 ENSMUST00000070515.1
Ephx2
epoxide hydrolase 2, cytoplasmic
chr9_-_123678782 0.951 ENSMUST00000170591.1
ENSMUST00000171647.1
Slc6a20a

solute carrier family 6 (neurotransmitter transporter), member 20A

chr10_-_77166545 0.935 ENSMUST00000081654.6
Col18a1
collagen, type XVIII, alpha 1
chr9_+_119063429 0.883 ENSMUST00000141185.1
ENSMUST00000126251.1
ENSMUST00000136561.1
Vill


villin-like


chr5_-_43981757 0.876 ENSMUST00000061299.7
Fgfbp1
fibroblast growth factor binding protein 1
chrM_+_8600 0.853 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chr10_+_18845071 0.827 ENSMUST00000019998.7
Perp
PERP, TP53 apoptosis effector
chr19_+_5474681 0.816 ENSMUST00000165485.1
ENSMUST00000166253.1
ENSMUST00000167371.1
ENSMUST00000167855.1
ENSMUST00000070118.7
Efemp2




epidermal growth factor-containing fibulin-like extracellular matrix protein 2




chr7_-_142656018 0.802 ENSMUST00000178921.1
Igf2
insulin-like growth factor 2
chr11_+_109543694 0.788 ENSMUST00000106696.1
Arsg
arylsulfatase G
chrM_+_7005 0.783 ENSMUST00000082405.1
mt-Co2
mitochondrially encoded cytochrome c oxidase II
chr1_-_72284248 0.779 ENSMUST00000097698.4
ENSMUST00000027381.6
Pecr

peroxisomal trans-2-enoyl-CoA reductase

chr11_+_58171648 0.777 ENSMUST00000020820.1
Mrpl22
mitochondrial ribosomal protein L22
chr3_-_57294880 0.772 ENSMUST00000171384.1
Tm4sf1
transmembrane 4 superfamily member 1
chr7_-_46672537 0.767 ENSMUST00000049298.7
Tph1
tryptophan hydroxylase 1
chr2_+_109917639 0.760 ENSMUST00000046548.7
ENSMUST00000111037.2
Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chr18_+_57468478 0.753 ENSMUST00000091892.2
Ctxn3
cortexin 3
chr6_-_87335758 0.748 ENSMUST00000042025.9
Antxr1
anthrax toxin receptor 1
chr7_-_126676428 0.737 ENSMUST00000106373.1
Sult1a1
sulfotransferase family 1A, phenol-preferring, member 1
chr10_-_81350191 0.730 ENSMUST00000122993.1
Hmg20b
high mobility group 20B
chr7_-_126676357 0.718 ENSMUST00000106371.1
ENSMUST00000106372.3
ENSMUST00000155419.1
Sult1a1


sulfotransferase family 1A, phenol-preferring, member 1


chrM_+_11734 0.714 ENSMUST00000082418.1
mt-Nd5
mitochondrially encoded NADH dehydrogenase 5
chr10_-_81350389 0.711 ENSMUST00000020454.4
ENSMUST00000105324.2
ENSMUST00000154609.2
ENSMUST00000105323.1
Hmg20b



high mobility group 20B



chr14_-_26170283 0.678 ENSMUST00000100809.4
Plac9b
placenta specific 9b
chr10_-_81350305 0.654 ENSMUST00000167481.1
Hmg20b
high mobility group 20B
chr15_-_37459327 0.652 ENSMUST00000119730.1
ENSMUST00000120746.1
Ncald

neurocalcin delta

chr14_+_24490678 0.650 ENSMUST00000169826.1
ENSMUST00000112384.3
Rps24

ribosomal protein S24

chr11_+_59306920 0.643 ENSMUST00000000128.3
ENSMUST00000108783.3
Wnt9a

wingless-type MMTV integration site 9A

chr6_+_116650674 0.637 ENSMUST00000067354.5
ENSMUST00000178241.1
8430408G22Rik

RIKEN cDNA 8430408G22 gene

chr2_+_125136692 0.636 ENSMUST00000099452.2
Ctxn2
cortexin 2
chr8_-_21906412 0.632 ENSMUST00000051965.4
Defb11
defensin beta 11
chr9_+_72958785 0.622 ENSMUST00000098567.2
ENSMUST00000034734.8
Dyx1c1

dyslexia susceptibility 1 candidate 1 homolog (human)

chr1_-_155527083 0.607 ENSMUST00000097531.2
Gm5532
predicted gene 5532
chr8_-_4779513 0.604 ENSMUST00000022945.7
Shcbp1
Shc SH2-domain binding protein 1
chr14_-_118237016 0.595 ENSMUST00000170662.1
Sox21
SRY-box containing gene 21
chr2_-_144270852 0.558 ENSMUST00000110030.3
Snx5
sorting nexin 5
chr7_+_19361207 0.558 ENSMUST00000047621.7
Ppp1r13l
protein phosphatase 1, regulatory (inhibitor) subunit 13 like
chr17_-_53867041 0.548 ENSMUST00000061311.7
Mrps36-ps1
mitichondrial ribosomal protein S36, pseudogene 1
chr5_-_149053038 0.548 ENSMUST00000085546.6
Hmgb1
high mobility group box 1
chr1_+_58210397 0.543 ENSMUST00000040442.5
Aox4
aldehyde oxidase 4
chr11_+_116843278 0.542 ENSMUST00000106370.3
Mettl23
methyltransferase like 23
chr9_-_55512156 0.535 ENSMUST00000034866.8
Etfa
electron transferring flavoprotein, alpha polypeptide
chr4_+_145510759 0.535 ENSMUST00000105742.1
ENSMUST00000136309.1
Gm13225

predicted gene 13225

chr3_-_36475688 0.532 ENSMUST00000029266.8
Anxa5
annexin A5
chr11_+_80183851 0.524 ENSMUST00000017839.2
Rnf135
ring finger protein 135
chr4_-_14621805 0.517 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr1_-_133610253 0.508 ENSMUST00000166915.1
Snrpe
small nuclear ribonucleoprotein E
chr3_-_100489324 0.507 ENSMUST00000061455.8
Fam46c
family with sequence similarity 46, member C
chr12_-_80643799 0.507 ENSMUST00000166931.1
Erh
enhancer of rudimentary homolog (Drosophila)
chr4_+_43493345 0.500 ENSMUST00000030181.5
ENSMUST00000107922.2
Ccdc107

coiled-coil domain containing 107

chr9_+_109832998 0.497 ENSMUST00000119376.1
ENSMUST00000122343.1
Nme6

NME/NM23 nucleoside diphosphate kinase 6

chr16_+_18836573 0.496 ENSMUST00000055413.6
2510002D24Rik
RIKEN cDNA 2510002D24 gene
chr7_-_137410717 0.493 ENSMUST00000120340.1
ENSMUST00000117404.1
ENSMUST00000068996.6
9430038I01Rik


RIKEN cDNA 9430038I01 gene


chr11_+_98026695 0.478 ENSMUST00000092425.4
Rpl19
ribosomal protein L19
chr6_+_125215551 0.470 ENSMUST00000032487.7
ENSMUST00000100942.2
ENSMUST00000063588.8
Vamp1


vesicle-associated membrane protein 1


chr13_+_90923122 0.468 ENSMUST00000051955.7
Rps23
ribosomal protein S23
chr19_-_11604828 0.465 ENSMUST00000025582.4
Ms4a6d
membrane-spanning 4-domains, subfamily A, member 6D
chr2_+_125068118 0.463 ENSMUST00000070353.3
Slc24a5
solute carrier family 24, member 5
chr4_-_118489755 0.461 ENSMUST00000184261.1
Tie1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr15_+_102326400 0.454 ENSMUST00000165717.1
Pfdn5
prefoldin 5
chr2_+_144270900 0.450 ENSMUST00000028910.2
ENSMUST00000110027.1
Mgme1

mitochondrial genome maintainance exonuclease 1

chr11_-_115419917 0.449 ENSMUST00000106537.1
ENSMUST00000043931.2
ENSMUST00000073791.3
Atp5h


ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d


chr17_-_47834682 0.448 ENSMUST00000066368.6
Mdfi
MyoD family inhibitor
chr5_+_13398688 0.445 ENSMUST00000125629.1
Sema3a
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr8_-_84662841 0.441 ENSMUST00000060427.4
Ier2
immediate early response 2
chr2_+_71389239 0.438 ENSMUST00000028408.2
Hat1
histone aminotransferase 1
chr17_-_15527281 0.435 ENSMUST00000154293.1
ENSMUST00000054450.6
Pdcd2

programmed cell death 2

chr19_-_41933276 0.434 ENSMUST00000075280.4
ENSMUST00000112123.2
Exosc1

exosome component 1

chr4_+_147132038 0.434 ENSMUST00000084149.3
Gm13139
predicted gene 13139
chr15_+_98571004 0.429 ENSMUST00000023728.6
4930415O20Rik
RIKEN cDNA 4930415O20 gene
chr17_-_55915870 0.422 ENSMUST00000074828.4
Rpl21-ps6
ribosomal protein L21, pseudogene 6
chr6_-_28397999 0.421 ENSMUST00000035930.4
Zfp800
zinc finger protein 800
chr2_+_32606946 0.415 ENSMUST00000113290.1
St6galnac6
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr11_+_98026918 0.414 ENSMUST00000017548.6
Rpl19
ribosomal protein L19
chr8_+_84689247 0.413 ENSMUST00000109767.2
ENSMUST00000177084.1
ENSMUST00000109768.2
ENSMUST00000152301.2
ENSMUST00000177423.1
Trmt1




tRNA methyltransferase 1




chr5_-_151651216 0.413 ENSMUST00000038131.9
Rfc3
replication factor C (activator 1) 3
chr8_-_106573461 0.411 ENSMUST00000073722.5
Gm10073
predicted pseudogene 10073
chr2_-_155357392 0.410 ENSMUST00000165234.1
ENSMUST00000077626.6
Pigu

phosphatidylinositol glycan anchor biosynthesis, class U

chr2_+_131491764 0.407 ENSMUST00000028806.5
ENSMUST00000110179.2
ENSMUST00000110189.2
ENSMUST00000110182.2
ENSMUST00000110183.2
ENSMUST00000110186.2
ENSMUST00000110188.1
Smox






spermine oxidase






chr11_-_4095344 0.406 ENSMUST00000004868.5
Mtfp1
mitochondrial fission process 1
chr5_+_3543812 0.405 ENSMUST00000115527.3
Fam133b
family with sequence similarity 133, member B
chr8_-_70510322 0.405 ENSMUST00000140679.1
ENSMUST00000129909.1
ENSMUST00000081940.4
Uba52


ubiquitin A-52 residue ribosomal protein fusion product 1


chr4_+_105789869 0.398 ENSMUST00000184254.1
Gm12728
predicted gene 12728
chr5_-_62766153 0.398 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr6_-_101377342 0.390 ENSMUST00000151175.1
Pdzrn3
PDZ domain containing RING finger 3
chr8_+_84689308 0.385 ENSMUST00000125370.3
ENSMUST00000175784.1
Trmt1

tRNA methyltransferase 1

chr14_+_26119811 0.385 ENSMUST00000173617.1
Duxbl2
doubl homeobox B-like 2
chr14_+_54686171 0.384 ENSMUST00000038539.6
1700123O20Rik
RIKEN cDNA 1700123O20 gene
chr12_+_16653470 0.381 ENSMUST00000111064.1
Ntsr2
neurotensin receptor 2
chr15_+_97964220 0.375 ENSMUST00000064200.7
Tmem106c
transmembrane protein 106C
chr11_+_102189620 0.375 ENSMUST00000070334.3
ENSMUST00000078975.7
G6pc3

glucose 6 phosphatase, catalytic, 3

chr11_-_102946688 0.374 ENSMUST00000057849.5
C1ql1
complement component 1, q subcomponent-like 1
chr6_-_83506895 0.367 ENSMUST00000113888.1
ENSMUST00000014698.3
Dguok

deoxyguanosine kinase

chr5_-_106926245 0.366 ENSMUST00000117588.1
Hfm1
HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
chr16_-_35363842 0.365 ENSMUST00000043521.4
Sec22a
SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
chr15_+_102326369 0.364 ENSMUST00000169637.1
ENSMUST00000165671.1
Pfdn5

prefoldin 5

chr1_+_24177610 0.363 ENSMUST00000054588.8
Col9a1
collagen, type IX, alpha 1
chr1_+_93685574 0.356 ENSMUST00000027499.6
Bok
BCL2-related ovarian killer protein
chr19_+_8735808 0.355 ENSMUST00000049424.9
Wdr74
WD repeat domain 74
chr5_-_138171248 0.354 ENSMUST00000153867.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr9_+_92457369 0.353 ENSMUST00000034941.7
Plscr4
phospholipid scramblase 4
chr10_-_128804353 0.351 ENSMUST00000051011.7
Tmem198b
transmembrane protein 198b
chr9_+_102834961 0.349 ENSMUST00000035142.6
Ryk
receptor-like tyrosine kinase
chr3_+_89459118 0.341 ENSMUST00000029564.5
Pmvk
phosphomevalonate kinase
chr3_-_116712644 0.329 ENSMUST00000029569.2
Slc35a3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr12_+_111814170 0.323 ENSMUST00000021714.7
Zfyve21
zinc finger, FYVE domain containing 21
chr14_+_26259109 0.322 ENSMUST00000174494.1
Duxbl3
double homeobox B-like 3
chr12_-_87444017 0.321 ENSMUST00000091090.4
2700073G19Rik
RIKEN cDNA 2700073G19 gene
chr4_-_147809788 0.320 ENSMUST00000105734.3
ENSMUST00000176201.1
Gm13157
Gm20707
predicted gene 13157
predicted gene 20707
chr14_+_55559993 0.318 ENSMUST00000117236.1
Dcaf11
DDB1 and CUL4 associated factor 11
chr4_+_122996035 0.316 ENSMUST00000030407.7
Mycl
v-myc myelocytomatosis viral oncogene homolog, lung carcinoma derived (avian)
chr12_-_75735729 0.312 ENSMUST00000021450.4
Sgpp1
sphingosine-1-phosphate phosphatase 1
chr4_+_122995944 0.311 ENSMUST00000106252.2
Mycl
v-myc myelocytomatosis viral oncogene homolog, lung carcinoma derived (avian)
chr1_-_175979114 0.310 ENSMUST00000104983.1
B020018G12Rik
RIKEN cDNA B020018G12 gene
chr7_+_3703979 0.305 ENSMUST00000006496.8
Rps9
ribosomal protein S9
chr17_-_26099257 0.303 ENSMUST00000053575.3
Gm8186
predicted gene 8186
chr18_-_10706688 0.302 ENSMUST00000002549.7
ENSMUST00000117726.1
ENSMUST00000117828.1
Abhd3


abhydrolase domain containing 3


chr5_-_114823460 0.302 ENSMUST00000140374.1
ENSMUST00000100850.4
Gm20499
2610524H06Rik
predicted gene 20499
RIKEN cDNA 2610524H06 gene
chr19_+_5088534 0.299 ENSMUST00000025811.4
Yif1a
Yip1 interacting factor homolog A (S. cerevisiae)
chr3_+_94372794 0.297 ENSMUST00000029795.3
Rorc
RAR-related orphan receptor gamma
chr2_+_20737306 0.296 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4

enhancer trap locus 4

chr11_-_115187321 0.295 ENSMUST00000103038.1
ENSMUST00000103039.1
ENSMUST00000103040.4
Nat9


N-acetyltransferase 9 (GCN5-related, putative)


chr3_+_146121655 0.282 ENSMUST00000039450.4
Mcoln3
mucolipin 3
chr17_+_31520115 0.278 ENSMUST00000046288.8
ENSMUST00000064798.8
Ndufv3

NADH dehydrogenase (ubiquinone) flavoprotein 3

chr4_-_150914401 0.274 ENSMUST00000105675.1
Park7
Parkinson disease (autosomal recessive, early onset) 7
chr2_-_105017015 0.273 ENSMUST00000111110.2
ENSMUST00000028592.5
Eif3m

eukaryotic translation initiation factor 3, subunit M

chr13_+_76579670 0.273 ENSMUST00000126960.1
ENSMUST00000109583.2
Mctp1

multiple C2 domains, transmembrane 1

chr18_+_12741324 0.265 ENSMUST00000115857.2
ENSMUST00000121018.1
ENSMUST00000119108.1
Cabyr


calcium-binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2)


chr2_-_5063932 0.265 ENSMUST00000027986.4
Optn
optineurin
chr7_+_101896340 0.263 ENSMUST00000035395.7
ENSMUST00000106973.1
ENSMUST00000144207.1
Anapc15


anaphase prompoting complex C subunit 15


chr4_+_145585166 0.261 ENSMUST00000105739.1
ENSMUST00000119718.1
Gm13212

predicted gene 13212

chr10_-_128626464 0.260 ENSMUST00000026420.5
Rps26
ribosomal protein S26
chr16_-_10543028 0.247 ENSMUST00000184863.1
ENSMUST00000038281.5
Dexi

dexamethasone-induced transcript

chr16_-_36874806 0.246 ENSMUST00000075946.5
Eaf2
ELL associated factor 2
chr9_-_22117123 0.237 ENSMUST00000013966.6
Elof1
elongation factor 1 homolog (ELF1, S. cerevisiae)
chr16_-_26989974 0.232 ENSMUST00000089832.4
Gmnc
geminin coiled-coil domain containing
chr1_+_161070767 0.230 ENSMUST00000111618.1
ENSMUST00000111620.3
ENSMUST00000028035.7
Cenpl


centromere protein L


chr5_-_138170992 0.226 ENSMUST00000139983.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr5_-_100373484 0.225 ENSMUST00000182433.1
Sec31a
Sec31 homolog A (S. cerevisiae)
chr12_+_10390756 0.216 ENSMUST00000020947.5
Rdh14
retinol dehydrogenase 14 (all-trans and 9-cis)
chr19_-_29334646 0.215 ENSMUST00000044143.5
Rln1
relaxin 1
chr12_-_55302974 0.214 ENSMUST00000021410.8
Ppp2r3c
protein phosphatase 2, regulatory subunit B'', gamma
chr17_-_36032682 0.213 ENSMUST00000102678.4
H2-T23
histocompatibility 2, T region locus 23
chr2_-_34826071 0.211 ENSMUST00000113077.1
ENSMUST00000028220.3
Fbxw2

F-box and WD-40 domain protein 2

chr12_-_113361232 0.205 ENSMUST00000103423.1
Ighg3
Immunoglobulin heavy constant gamma 3
chr17_+_29274078 0.203 ENSMUST00000149405.2
BC004004
cDNA sequence BC004004
chr18_-_36454487 0.201 ENSMUST00000025204.5
Pfdn1
prefoldin 1
chr6_+_124304646 0.201 ENSMUST00000112541.2
ENSMUST00000032234.2
Cd163

CD163 antigen

chr15_-_79774383 0.200 ENSMUST00000069877.5
Dnal4
dynein, axonemal, light chain 4
chr8_-_83442648 0.186 ENSMUST00000167525.1
Scoc
short coiled-coil protein
chr17_-_43543639 0.183 ENSMUST00000178772.1
Ankrd66
ankyrin repeat domain 66
chr11_-_29247208 0.181 ENSMUST00000020754.3
Ccdc104
coiled-coil domain containing 104
chr12_-_85824506 0.180 ENSMUST00000021676.5
ENSMUST00000142331.1
0610007P14Rik

RIKEN cDNA 0610007P14 gene

chr3_+_27938638 0.180 ENSMUST00000120834.1
Pld1
phospholipase D1
chr2_-_5063996 0.179 ENSMUST00000114996.1
Optn
optineurin
chr7_+_28808795 0.177 ENSMUST00000172529.1
Hnrnpl
heterogeneous nuclear ribonucleoprotein L
chr13_+_67813740 0.176 ENSMUST00000181391.1
ENSMUST00000012725.7
Zfp273

zinc finger protein 273

chr14_+_25980039 0.173 ENSMUST00000173155.1
Duxbl1
double homeobox B-like 1
chr15_-_9140374 0.172 ENSMUST00000096482.3
ENSMUST00000110585.2
Skp2

S-phase kinase-associated protein 2 (p45)

chr17_+_80290206 0.172 ENSMUST00000061703.9
Morn2
MORN repeat containing 2
chr12_+_84361968 0.167 ENSMUST00000021661.6
Coq6
coenzyme Q6 homolog (yeast)
chr2_-_73453918 0.167 ENSMUST00000102679.1
Wipf1
WAS/WASL interacting protein family, member 1
chr10_-_81407641 0.166 ENSMUST00000140916.1
Nfic
nuclear factor I/C
chr5_-_63968867 0.165 ENSMUST00000154169.1
Rell1
RELT-like 1
chr2_+_32606979 0.162 ENSMUST00000113289.1
ENSMUST00000095044.3
St6galnac6

ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

chr14_+_118854695 0.162 ENSMUST00000100314.3
Cldn10
claudin 10
chr7_+_29238434 0.162 ENSMUST00000108237.1
Yif1b
Yip1 interacting factor homolog B (S. cerevisiae)
chr5_-_87490869 0.156 ENSMUST00000147854.1
Ugt2a1
UDP glucuronosyltransferase 2 family, polypeptide A1
chr11_-_80377975 0.152 ENSMUST00000179332.1
ENSMUST00000103225.4
ENSMUST00000134274.1
5730455P16Rik


RIKEN cDNA 5730455P16 gene


chrX_-_23266751 0.150 ENSMUST00000115316.2
Klhl13
kelch-like 13
chr18_-_56975333 0.146 ENSMUST00000139243.2
ENSMUST00000025488.8
C330018D20Rik

RIKEN cDNA C330018D20 gene

chr6_+_145934113 0.144 ENSMUST00000032383.7
Sspn
sarcospan
chr7_-_30559600 0.140 ENSMUST00000043975.4
ENSMUST00000156241.1
Lin37

lin-37 homolog (C. elegans)

chr1_+_86021935 0.139 ENSMUST00000052854.6
ENSMUST00000125083.1
ENSMUST00000152501.1
ENSMUST00000113344.1
ENSMUST00000130504.1
ENSMUST00000153247.2
Spata3





spermatogenesis associated 3





chr7_-_30559828 0.138 ENSMUST00000108164.1
Lin37
lin-37 homolog (C. elegans)
chr1_+_190928492 0.138 ENSMUST00000066632.7
ENSMUST00000110899.1
Angel2

angel homolog 2 (Drosophila)


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.7 GO:0072592 oxygen metabolic process(GO:0072592)
0.5 1.4 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.4 4.0 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.3 1.0 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) olefin metabolic process(GO:1900673)
0.3 0.8 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.3 2.1 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.3 0.8 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.2 0.7 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.2 2.0 GO:0015838 proline transport(GO:0015824) amino-acid betaine transport(GO:0015838)
0.2 0.4 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.2 0.5 GO:0045819 plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819)
0.2 0.5 GO:0046110 xanthine metabolic process(GO:0046110)
0.2 0.3 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.2 1.3 GO:0048625 myoblast fate commitment(GO:0048625)
0.2 2.1 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 0.9 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 2.4 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 0.8 GO:0002934 desmosome organization(GO:0002934)
0.1 0.5 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.1 1.5 GO:0051923 sulfation(GO:0051923)
0.1 0.4 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.4 GO:0061743 motor learning(GO:0061743)
0.1 0.4 GO:0097360 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.1 0.5 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1 0.4 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.8 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.4 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.4 GO:0021856 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.1 1.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.4 GO:0046208 spermine catabolic process(GO:0046208)
0.1 0.3 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.1 0.3 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.1 0.2 GO:2000564 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.1 1.8 GO:0033194 response to hydroperoxide(GO:0033194)
0.1 0.4 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.5 GO:0019532 oxalate transport(GO:0019532)
0.1 0.3 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.1 0.4 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.1 0.6 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.4 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.1 0.7 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.1 0.1 GO:0021886 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.1 0.6 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 0.8 GO:0030497 fatty acid elongation(GO:0030497)
0.1 0.2 GO:0010749 regulation of nitric oxide mediated signal transduction(GO:0010749)
0.1 1.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.9 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1 1.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.2 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.4 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.5 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.4 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.5 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.3 GO:0072615 interleukin-17 secretion(GO:0072615)
0.0 1.3 GO:0071384 cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385)
0.0 0.6 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 2.3 GO:0022904 respiratory electron transport chain(GO:0022904)
0.0 0.5 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.4 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.6 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.2 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 1.0 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.0 1.9 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 0.1 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.0 0.5 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.2 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.3 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.4 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.1 GO:1902741 type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.0 0.6 GO:0006907 pinocytosis(GO:0006907)
0.0 0.5 GO:0018126 protein hydroxylation(GO:0018126)
0.0 0.3 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 1.0 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.5 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 0.2 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.1 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.1 GO:0042360 vitamin E metabolic process(GO:0042360)
0.0 0.4 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 0.4 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.2 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.9 GO:0051693 actin filament capping(GO:0051693)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.2 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.0 0.7 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.0 GO:1902605 heterotrimeric G-protein complex assembly(GO:1902605)
0.0 0.3 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.2 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.0 0.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.3 GO:0002183 cytoplasmic translational initiation(GO:0002183)
0.0 0.2 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.0 0.0 GO:1902498 regulation of protein K63-linked ubiquitination(GO:1900044) regulation of protein autoubiquitination(GO:1902498)
0.0 0.2 GO:0006953 acute-phase response(GO:0006953)
0.0 0.1 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.1 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.4 1.5 GO:0071438 invadopodium membrane(GO:0071438)
0.4 1.1 GO:0042585 germinal vesicle(GO:0042585)
0.1 1.3 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 2.6 GO:0098644 complex of collagen trimers(GO:0098644)
0.1 0.5 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.1 1.0 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.5 GO:0070820 tertiary granule(GO:0070820)
0.1 0.4 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 0.6 GO:0097422 tubular endosome(GO:0097422)
0.1 0.4 GO:0044301 climbing fiber(GO:0044301)
0.1 6.1 GO:0070469 respiratory chain(GO:0070469)
0.1 0.5 GO:0005687 U4 snRNP(GO:0005687)
0.1 0.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 0.4 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 0.4 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 1.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.7 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.5 GO:0034709 methylosome(GO:0034709)
0.0 0.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.5 GO:0042555 MCM complex(GO:0042555)
0.0 1.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.3 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.9 GO:0005581 collagen trimer(GO:0005581)
0.0 0.3 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 1.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 4.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.1 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.1 GO:0097413 Lewy body(GO:0097413)
0.0 0.8 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.2 GO:0043231 intracellular membrane-bounded organelle(GO:0043231)
0.0 2.6 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.1 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.0 0.6 GO:0045171 intercellular bridge(GO:0045171)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.5 1.5 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.5 1.5 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.4 2.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.3 1.6 GO:0019770 IgG receptor activity(GO:0019770)
0.3 0.8 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.2 2.0 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.2 1.0 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.2 1.2 GO:1990932 5.8S rRNA binding(GO:1990932)
0.2 0.5 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.2 4.8 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2 0.8 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 0.5 GO:0030151 molybdenum ion binding(GO:0030151)
0.1 0.4 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.1 2.1 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 0.3 GO:0052740 phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 1.3 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 0.5 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.4 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 0.3 GO:0036470 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.1 0.6 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.4 GO:0034235 GPI anchor binding(GO:0034235)
0.1 0.6 GO:0034452 dynactin binding(GO:0034452)
0.1 0.4 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.1 1.6 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 1.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.1 3.8 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.9 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.1 0.8 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 1.3 GO:0070016 gamma-catenin binding(GO:0045295) armadillo repeat domain binding(GO:0070016)
0.1 0.5 GO:1990446 U1 snRNP binding(GO:1990446)
0.1 0.8 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 1.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.4 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.5 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.0 0.4 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.4 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.4 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.4 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.0 0.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.9 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.9 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 1.3 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.5 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.4 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.4 GO:0051400 BH domain binding(GO:0051400)
0.0 0.9 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.4 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.5 GO:0009055 electron carrier activity(GO:0009055)
0.0 1.5 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:1990715 mRNA CDS binding(GO:1990715)
0.0 1.1 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.6 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.4 GO:0005402 cation:sugar symporter activity(GO:0005402)
0.0 0.1 GO:0051378 primary amine oxidase activity(GO:0008131) serotonin binding(GO:0051378)
0.0 0.7 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0005113 patched binding(GO:0005113) cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.6 GO:0046983 protein dimerization activity(GO:0046983)
0.0 0.5 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.0 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
0.0 0.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.4 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.0 0.2 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.4 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 1.0 GO:0051082 unfolded protein binding(GO:0051082)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.5 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 2.0 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.7 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.0 1.3 NABA_COLLAGENS Genes encoding collagen proteins
0.0 1.4 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 1.5 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 1.3 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.9 PID_ATR_PATHWAY ATR signaling pathway
0.0 0.8 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.5 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.3 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.8 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.9 PID_P73PATHWAY p73 transcription factor network
0.0 0.4 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.2 PID_MYC_PATHWAY C-MYC pathway
0.0 0.3 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.4 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.0 0.9 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.4 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 1.4 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.6 PID_P53_REGULATION_PATHWAY p53 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.0 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.2 1.5 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.2 2.1 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.1 1.1 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 0.8 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 0.8 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.1 REACTOME_TRAF6_MEDIATED_NFKB_ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.4 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 1.0 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.5 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.7 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.5 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.7 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.4 REACTOME_POL_SWITCHING Genes involved in Polymerase switching
0.0 1.0 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.5 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.0 0.3 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.4 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.4 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.4 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.4 REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.2 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.4 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.0 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 0.8 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.3 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 1.8 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.3 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.0 0.2 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.8 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 0.4 REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.1 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism