Motif ID: Tgif2_Tgif2lx1_Tgif2lx2

Z-value: 0.770

Transcription factors associated with Tgif2_Tgif2lx1_Tgif2lx2:

Gene SymbolEntrez IDGene Name
Tgif2 ENSMUSG00000062175.7 Tgif2
Tgif2lx1 ENSMUSG00000061283.4 Tgif2lx1
Tgif2lx2 ENSMUSG00000063242.6 Tgif2lx2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tgif2mm10_v2_chr2_+_156840077_156840141-0.314.6e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Tgif2_Tgif2lx1_Tgif2lx2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_19103022 8.614 ENSMUST00000037294.7
Tfap2d
transcription factor AP-2, delta
chr2_+_82053222 3.292 ENSMUST00000047527.7
Zfp804a
zinc finger protein 804A
chr17_+_86753900 3.146 ENSMUST00000024954.9
Epas1
endothelial PAS domain protein 1
chr15_+_85510812 2.957 ENSMUST00000079690.2
Gm4825
predicted pseudogene 4825
chr5_-_45857473 2.869 ENSMUST00000016026.7
ENSMUST00000067997.6
ENSMUST00000045586.6
Lcorl


ligand dependent nuclear receptor corepressor-like


chr11_+_115154139 2.679 ENSMUST00000021076.5
Rab37
RAB37, member of RAS oncogene family
chr5_-_100159261 2.624 ENSMUST00000139520.1
Tmem150c
transmembrane protein 150C
chr13_-_76385028 2.595 ENSMUST00000099365.1
Gm10760
predicted gene 10760
chr7_-_44670820 2.052 ENSMUST00000048102.7
Myh14
myosin, heavy polypeptide 14
chr7_+_51621830 1.888 ENSMUST00000032710.5
Slc17a6
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
chr1_-_52727457 1.821 ENSMUST00000156876.1
ENSMUST00000087701.3
Mfsd6

major facilitator superfamily domain containing 6

chr9_+_78175898 1.729 ENSMUST00000180974.1
C920006O11Rik
RIKEN cDNA C920006O11 gene
chr13_+_54949388 1.709 ENSMUST00000026994.7
ENSMUST00000109994.2
Unc5a

unc-5 homolog A (C. elegans)

chr6_-_106800051 1.658 ENSMUST00000013882.7
ENSMUST00000049675.4
ENSMUST00000113239.3
Crbn


cereblon


chr6_-_88875035 1.564 ENSMUST00000145944.1
Podxl2
podocalyxin-like 2
chr7_-_61982348 1.550 ENSMUST00000181804.1
ENSMUST00000181187.1
A330076H08Rik

RIKEN cDNA A330076H08 gene

chr17_+_87025550 1.517 ENSMUST00000024959.3
ENSMUST00000160269.1
Cript

cysteine-rich PDZ-binding protein

chr7_-_61982290 1.379 ENSMUST00000180481.1
A330076H08Rik
RIKEN cDNA A330076H08 gene
chr17_-_6477102 1.342 ENSMUST00000167717.2
Tmem181b-ps
transmembrane protein 181B, pseudogene
chr17_-_36989504 1.302 ENSMUST00000169189.1
H2-M5
histocompatibility 2, M region locus 5
chr11_+_98348404 1.298 ENSMUST00000078694.6
Ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr16_+_7069825 1.296 ENSMUST00000056416.7
Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr10_-_81430966 1.267 ENSMUST00000117966.1
Nfic
nuclear factor I/C
chr3_-_146770603 1.255 ENSMUST00000106138.1
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr8_-_70439557 1.247 ENSMUST00000076615.5
Crtc1
CREB regulated transcription coactivator 1
chr6_-_88874597 1.238 ENSMUST00000061262.4
ENSMUST00000140455.1
ENSMUST00000145780.1
Podxl2


podocalyxin-like 2


chr1_+_36307745 1.221 ENSMUST00000142319.1
ENSMUST00000097778.2
ENSMUST00000115031.1
ENSMUST00000115032.1
ENSMUST00000137906.1
ENSMUST00000115029.1
Arid5a





AT rich interactive domain 5A (MRF1-like)





chr15_-_33687840 1.152 ENSMUST00000042021.3
Tspyl5
testis-specific protein, Y-encoded-like 5
chr2_-_120970706 1.113 ENSMUST00000028728.5
Ubr1
ubiquitin protein ligase E3 component n-recognin 1
chr2_-_25461094 1.112 ENSMUST00000114261.2
BC029214
cDNA sequence BC029214
chr11_+_23306884 1.105 ENSMUST00000180046.1
Usp34
ubiquitin specific peptidase 34
chr14_+_55560904 1.091 ENSMUST00000072530.4
ENSMUST00000128490.1
Dcaf11

DDB1 and CUL4 associated factor 11

chr11_+_23306910 1.074 ENSMUST00000137823.1
Usp34
ubiquitin specific peptidase 34
chr3_-_146770218 1.058 ENSMUST00000106137.1
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr7_-_12422488 1.047 ENSMUST00000120220.1
Zfp551
zinc fingr protein 551
chr6_+_112273758 1.043 ENSMUST00000032376.5
Lmcd1
LIM and cysteine-rich domains 1
chr4_-_87806276 1.027 ENSMUST00000148059.1
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr14_+_55561060 1.020 ENSMUST00000117701.1
Dcaf11
DDB1 and CUL4 associated factor 11
chr7_-_80401707 1.014 ENSMUST00000120753.1
Furin
furin (paired basic amino acid cleaving enzyme)
chr9_+_48362034 0.981 ENSMUST00000093853.4
Nxpe4
neurexophilin and PC-esterase domain family, member 4
chr4_-_87806296 0.976 ENSMUST00000126353.1
ENSMUST00000149357.1
Mllt3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr13_+_41606216 0.941 ENSMUST00000129449.1
Tmem170b
transmembrane protein 170B
chr19_-_33761949 0.937 ENSMUST00000025694.6
ENSMUST00000147153.1
Lipo1
Lipo2
lipase, member O1
lipase, member O2
chr15_+_40655020 0.927 ENSMUST00000053467.4
Zfpm2
zinc finger protein, multitype 2
chr11_-_20741447 0.897 ENSMUST00000177543.1
Aftph
aftiphilin
chr7_+_107370728 0.867 ENSMUST00000137663.1
ENSMUST00000073459.5
Syt9

synaptotagmin IX

chr7_-_42578588 0.848 ENSMUST00000179470.1
Gm21028
predicted gene, 21028
chr10_+_60106198 0.835 ENSMUST00000121820.2
Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr7_-_4789541 0.831 ENSMUST00000168578.1
Tmem238
transmembrane protein 238
chr1_-_163725123 0.826 ENSMUST00000159679.1
Mettl11b
methyltransferase like 11B
chr3_+_107877227 0.818 ENSMUST00000037375.8
Eps8l3
EPS8-like 3
chr5_-_124095749 0.801 ENSMUST00000031354.4
Abcb9
ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr11_+_85353156 0.800 ENSMUST00000108061.1
ENSMUST00000108062.1
ENSMUST00000108056.1
ENSMUST00000138423.1
ENSMUST00000074875.4
ENSMUST00000092821.3
Bcas3





breast carcinoma amplified sequence 3





chr11_+_32000452 0.769 ENSMUST00000020537.2
ENSMUST00000109409.1
Nsg2

neuron specific gene family member 2

chr14_+_45351473 0.753 ENSMUST00000111835.2
Styx
serine/threonine/tyrosine interaction protein
chr2_-_168741752 0.746 ENSMUST00000029060.4
Atp9a
ATPase, class II, type 9A
chr2_+_32721055 0.734 ENSMUST00000074248.4
Sh2d3c
SH2 domain containing 3C
chr7_-_137410717 0.734 ENSMUST00000120340.1
ENSMUST00000117404.1
ENSMUST00000068996.6
9430038I01Rik


RIKEN cDNA 9430038I01 gene


chr2_-_27246814 0.725 ENSMUST00000149733.1
Sardh
sarcosine dehydrogenase
chr3_-_146812951 0.720 ENSMUST00000102515.3
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr8_-_41133697 0.696 ENSMUST00000155055.1
ENSMUST00000059115.6
ENSMUST00000145860.1
Mtus1


mitochondrial tumor suppressor 1


chr9_-_85749308 0.672 ENSMUST00000039213.8
Ibtk
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr13_-_12464925 0.655 ENSMUST00000124888.1
Lgals8
lectin, galactose binding, soluble 8
chr18_-_80934054 0.647 ENSMUST00000091790.3
Atp9b
ATPase, class II, type 9B
chr8_-_70839720 0.633 ENSMUST00000002989.9
Arrdc2
arrestin domain containing 2
chr16_+_19028232 0.611 ENSMUST00000074116.4
Gm10088
predicted gene 10088
chr15_+_85832301 0.607 ENSMUST00000146088.1
Ttc38
tetratricopeptide repeat domain 38
chr17_+_6270475 0.605 ENSMUST00000088940.4
Tmem181a
transmembrane protein 181A
chr7_+_83584910 0.598 ENSMUST00000039317.7
ENSMUST00000164944.1
Tmc3

transmembrane channel-like gene family 3

chr2_-_7395968 0.596 ENSMUST00000002176.6
Celf2
CUGBP, Elav-like family member 2
chr11_-_5741141 0.595 ENSMUST00000140922.1
ENSMUST00000093362.5
Urgcp

upregulator of cell proliferation

chr3_-_57301919 0.564 ENSMUST00000029376.8
Tm4sf1
transmembrane 4 superfamily member 1
chr9_-_44134481 0.553 ENSMUST00000180670.1
Gm10687
predicted gene 10687
chr2_+_49451486 0.544 ENSMUST00000092123.4
Epc2
enhancer of polycomb homolog 2 (Drosophila)
chr1_-_133753681 0.536 ENSMUST00000125659.1
ENSMUST00000165602.2
ENSMUST00000048953.7
Atp2b4


ATPase, Ca++ transporting, plasma membrane 4


chr8_+_125054195 0.507 ENSMUST00000118942.1
ENSMUST00000117658.1
ENSMUST00000074562.4
ENSMUST00000098311.4
ENSMUST00000115885.2
ENSMUST00000075730.4
ENSMUST00000122389.1
ENSMUST00000121953.1
Disc1







disrupted in schizophrenia 1







chr11_+_32000496 0.505 ENSMUST00000093219.3
Nsg2
neuron specific gene family member 2
chr2_+_130405256 0.493 ENSMUST00000110281.1
ENSMUST00000028898.3
1700020A23Rik

RIKEN cDNA 1700020A23 gene

chr3_-_107969162 0.488 ENSMUST00000004136.8
ENSMUST00000106678.1
Gstm3

glutathione S-transferase, mu 3

chr1_-_93101854 0.462 ENSMUST00000171796.1
ENSMUST00000171556.1
Kif1a

kinesin family member 1A

chr1_-_172632931 0.430 ENSMUST00000027826.5
Dusp23
dual specificity phosphatase 23
chr8_+_122611618 0.428 ENSMUST00000015157.8
Trappc2l
trafficking protein particle complex 2-like
chr3_-_78892451 0.422 ENSMUST00000164923.1
Gm5277
predicted gene 5277
chr8_+_3655762 0.418 ENSMUST00000012849.8
ENSMUST00000169234.2
Retn

resistin

chr5_-_36582381 0.409 ENSMUST00000141043.1
ENSMUST00000031094.8
Tbc1d14

TBC1 domain family, member 14

chr5_-_38502107 0.402 ENSMUST00000005238.6
Slc2a9
solute carrier family 2 (facilitated glucose transporter), member 9
chr16_-_17576631 0.397 ENSMUST00000164545.1
ENSMUST00000164490.1
ENSMUST00000172164.1
Slc7a4


solute carrier family 7 (cationic amino acid transporter, y+ system), member 4


chr7_+_48789003 0.392 ENSMUST00000118927.1
ENSMUST00000125280.1
Zdhhc13

zinc finger, DHHC domain containing 13

chr17_+_21423227 0.385 ENSMUST00000165230.1
ENSMUST00000007884.8
ENSMUST00000167749.1
Zfp54


zinc finger protein 54


chr14_-_54877532 0.377 ENSMUST00000168622.1
ENSMUST00000177403.1
Ppp1r3e

protein phosphatase 1, regulatory (inhibitor) subunit 3E

chr11_-_20332689 0.373 ENSMUST00000109594.1
Slc1a4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr13_-_33935782 0.365 ENSMUST00000168350.1
ENSMUST00000167260.1
Serpinb6a

serine (or cysteine) peptidase inhibitor, clade B, member 6a

chr7_+_4137475 0.355 ENSMUST00000154571.1
Leng8
leukocyte receptor cluster (LRC) member 8
chr4_-_82859571 0.350 ENSMUST00000156055.1
ENSMUST00000030110.8
Zdhhc21

zinc finger, DHHC domain containing 21

chr2_+_30392405 0.347 ENSMUST00000113612.3
ENSMUST00000123202.1
Dolpp1

dolichyl pyrophosphate phosphatase 1

chr8_+_104250925 0.344 ENSMUST00000098464.4
Cklf
chemokine-like factor
chr6_+_142413441 0.339 ENSMUST00000088263.4
B230216G23Rik
RIKEN cDNA B230216G23 gene
chr1_-_93101825 0.329 ENSMUST00000112958.2
Kif1a
kinesin family member 1A
chrX_+_151344171 0.329 ENSMUST00000073364.5
Fam120c
family with sequence similarity 120, member C
chr10_+_39369750 0.303 ENSMUST00000063091.6
ENSMUST00000099967.3
ENSMUST00000126486.1
Fyn


Fyn proto-oncogene


chr17_-_55712571 0.302 ENSMUST00000086876.5
Pot1b
protection of telomeres 1B
chrY_+_90755657 0.279 ENSMUST00000167967.2
Gm21857
predicted gene, 21857
chr7_+_43562256 0.273 ENSMUST00000107972.1
Zfp658
zinc finger protein 658
chr7_+_45785331 0.265 ENSMUST00000120005.1
ENSMUST00000123585.1
Lmtk3

lemur tyrosine kinase 3

chr2_-_34826187 0.258 ENSMUST00000113075.1
ENSMUST00000113080.2
ENSMUST00000091020.3
Fbxw2


F-box and WD-40 domain protein 2


chr7_-_25477607 0.251 ENSMUST00000098669.1
ENSMUST00000098668.1
ENSMUST00000098666.2
Ceacam1


carcinoembryonic antigen-related cell adhesion molecule 1


chr5_+_148959263 0.248 ENSMUST00000135240.1
Gm15409
predicted gene 15409
chr2_-_34826071 0.247 ENSMUST00000113077.1
ENSMUST00000028220.3
Fbxw2

F-box and WD-40 domain protein 2

chr14_-_70653081 0.244 ENSMUST00000062629.4
Npm2
nucleophosmin/nucleoplasmin 2
chr3_+_14863495 0.237 ENSMUST00000029076.4
Car3
carbonic anhydrase 3
chr7_-_24316590 0.233 ENSMUST00000108436.1
ENSMUST00000032673.8
Zfp94

zinc finger protein 94

chr8_+_104250869 0.233 ENSMUST00000034342.5
Cklf
chemokine-like factor
chr17_+_26113286 0.230 ENSMUST00000025010.7
Tmem8
transmembrane protein 8 (five membrane-spanning domains)
chr12_-_32953772 0.223 ENSMUST00000180391.1
ENSMUST00000181670.1
4933406C10Rik

RIKEN cDNA 4933406C10 gene

chr2_+_30364227 0.219 ENSMUST00000077977.7
ENSMUST00000140075.2
Fam73b

family with sequence similarity 73, member B

chr9_-_51963533 0.203 ENSMUST00000034552.6
Fdx1
ferredoxin 1
chr8_-_72213636 0.196 ENSMUST00000109987.1
Gm11034
predicted gene 11034
chr18_+_63708689 0.190 ENSMUST00000072726.5
Wdr7
WD repeat domain 7
chr5_-_128433066 0.179 ENSMUST00000044441.6
Tmem132d
transmembrane protein 132D
chr2_-_121506639 0.176 ENSMUST00000089926.5
Mfap1a
microfibrillar-associated protein 1A
chr6_-_38046994 0.171 ENSMUST00000096040.4
Svopl
SV2 related protein homolog (rat)-like
chr10_+_120201586 0.165 ENSMUST00000156877.1
Tmbim4
transmembrane BAX inhibitor motif containing 4
chr6_-_29179584 0.164 ENSMUST00000159200.1
Prrt4
proline-rich transmembrane protein 4
chr3_+_105973711 0.162 ENSMUST00000000573.2
Ovgp1
oviductal glycoprotein 1
chr6_-_122820606 0.162 ENSMUST00000181317.1
Gm26826
predicted gene, 26826
chr2_+_110597298 0.159 ENSMUST00000045972.6
ENSMUST00000111026.2
Slc5a12

solute carrier family 5 (sodium/glucose cotransporter), member 12

chr17_+_32993123 0.158 ENSMUST00000087666.4
ENSMUST00000157017.1
Zfp952

zinc finger protein 952

chr11_+_30954389 0.157 ENSMUST00000020551.6
ENSMUST00000117883.1
Asb3

ankyrin repeat and SOCS box-containing 3

chr2_-_26380600 0.149 ENSMUST00000114115.2
ENSMUST00000035427.4
Snapc4

small nuclear RNA activating complex, polypeptide 4

chr4_+_11123950 0.147 ENSMUST00000142297.1
Gm11827
predicted gene 11827
chr15_+_82147238 0.145 ENSMUST00000023100.6
Srebf2
sterol regulatory element binding factor 2
chr9_-_108079279 0.141 ENSMUST00000162355.1
ENSMUST00000047746.6
ENSMUST00000174504.1
ENSMUST00000178267.1
ENSMUST00000160649.1
Rnf123




ring finger protein 123




chr17_-_26886175 0.140 ENSMUST00000108741.2
Gm17382
predicted gene, 17382
chr6_-_108185552 0.137 ENSMUST00000167338.1
ENSMUST00000172188.1
ENSMUST00000032191.9
Sumf1


sulfatase modifying factor 1


chr17_+_46202740 0.134 ENSMUST00000087031.5
Xpo5
exportin 5
chr5_-_114773488 0.133 ENSMUST00000178440.1
ENSMUST00000043283.7
ENSMUST00000112185.2
Git2


G protein-coupled receptor kinase-interactor 2


chr11_+_32455362 0.131 ENSMUST00000051053.4
Ubtd2
ubiquitin domain containing 2
chr1_-_162548484 0.128 ENSMUST00000028017.9
Mettl13
methyltransferase like 13
chr1_-_153408429 0.127 ENSMUST00000097535.4
E330020D12Rik
Riken cDNA E330020D12 gene
chr9_-_108079255 0.127 ENSMUST00000162516.1
Rnf123
ring finger protein 123
chr3_+_116594959 0.126 ENSMUST00000029571.8
Sass6
spindle assembly 6 homolog (C. elegans)
chr5_-_114773372 0.124 ENSMUST00000112183.1
ENSMUST00000086564.4
Git2

G protein-coupled receptor kinase-interactor 2

chr8_+_70724064 0.110 ENSMUST00000034307.7
ENSMUST00000110095.2
Pde4c

phosphodiesterase 4C, cAMP specific

chr1_+_185204165 0.100 ENSMUST00000069652.6
Rab3gap2
RAB3 GTPase activating protein subunit 2
chr10_+_82699007 0.099 ENSMUST00000020478.7
Hcfc2
host cell factor C2
chr2_-_128943985 0.093 ENSMUST00000028866.8
Zc3h8
zinc finger CCCH type containing 8
chrX_+_94367147 0.089 ENSMUST00000113897.2
ENSMUST00000113896.1
ENSMUST00000113895.1
Apoo


apolipoprotein O


chr4_-_149126688 0.089 ENSMUST00000030815.2
Cort
cortistatin
chr15_-_85811644 0.085 ENSMUST00000144067.1
ENSMUST00000134631.1
ENSMUST00000154814.1
ENSMUST00000071876.6
ENSMUST00000150995.1
Cdpf1




cysteine rich, DPF motif domain containing 1




chr15_+_10981747 0.083 ENSMUST00000070877.5
Amacr
alpha-methylacyl-CoA racemase
chr2_+_129065934 0.080 ENSMUST00000035812.7
Ttl
tubulin tyrosine ligase
chr10_-_30618337 0.075 ENSMUST00000019925.5
Hint3
histidine triad nucleotide binding protein 3
chr5_+_145283343 0.072 ENSMUST00000094116.3
Zscan25
zinc finger and SCAN domain containing 25
chr2_-_165473187 0.064 ENSMUST00000029208.8
ENSMUST00000109279.2
Slc13a3

solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3

chr2_-_7395879 0.064 ENSMUST00000182404.1
Celf2
CUGBP, Elav-like family member 2
chr8_+_25849618 0.064 ENSMUST00000098858.3
Kcnu1
potassium channel, subfamily U, member 1
chr2_-_120731503 0.063 ENSMUST00000110701.1
ENSMUST00000110700.1
Cdan1

congenital dyserythropoietic anemia, type I (human)

chr8_+_4226827 0.060 ENSMUST00000053035.6
Lrrc8e
leucine rich repeat containing 8 family, member E
chr13_-_25020289 0.060 ENSMUST00000021772.2
Mrs2
MRS2 magnesium homeostasis factor homolog (S. cerevisiae)
chr15_-_27681498 0.057 ENSMUST00000100739.3
Fam105a
family with sequence similarity 105, member A
chr3_+_134828993 0.051 ENSMUST00000029822.4
Tacr3
tachykinin receptor 3
chr7_+_28440927 0.050 ENSMUST00000078845.6
Gmfg
glia maturation factor, gamma
chr3_+_102010138 0.049 ENSMUST00000066187.4
Nhlh2
nescient helix loop helix 2
chr4_+_74251928 0.048 ENSMUST00000030102.5
Kdm4c
lysine (K)-specific demethylase 4C
chr9_-_62510498 0.041 ENSMUST00000164246.2
Coro2b
coronin, actin binding protein, 2B
chr8_+_72219726 0.040 ENSMUST00000003123.8
Fam32a
family with sequence similarity 32, member A
chrX_+_94367112 0.039 ENSMUST00000113898.1
Apoo
apolipoprotein O
chr19_-_5610038 0.036 ENSMUST00000113641.2
Kat5
K(lysine) acetyltransferase 5
chr2_+_26319741 0.035 ENSMUST00000066889.6
Gpsm1
G-protein signalling modulator 1 (AGS3-like, C. elegans)
chr5_-_134552414 0.032 ENSMUST00000100647.2
ENSMUST00000036999.6
Clip2

CAP-GLY domain containing linker protein 2

chr9_+_50768228 0.032 ENSMUST00000042391.6
Fdxacb1
ferredoxin-fold anticodon binding domain containing 1
chr18_+_78349754 0.027 ENSMUST00000164064.1
Gm6133
predicted gene 6133
chr6_+_115544664 0.026 ENSMUST00000040234.7
Tsen2
tRNA splicing endonuclease 2 homolog (S. cerevisiae)
chr11_+_83662579 0.025 ENSMUST00000019074.3
Ccl4
chemokine (C-C motif) ligand 4
chr8_-_3467617 0.024 ENSMUST00000111081.3
ENSMUST00000118194.1
ENSMUST00000004686.6
Pex11g


peroxisomal biogenesis factor 11 gamma


chr7_+_27927592 0.024 ENSMUST00000181644.1
Gm26891
predicted gene, 26891
chr2_-_136891363 0.022 ENSMUST00000028730.6
ENSMUST00000110089.2
Mkks

McKusick-Kaufman syndrome

chr1_-_16093286 0.017 ENSMUST00000145070.1
ENSMUST00000151004.1
4930444P10Rik

RIKEN cDNA 4930444P10 gene

chr9_+_86743616 0.009 ENSMUST00000036426.6
Prss35
protease, serine, 35
chr11_+_6292120 0.008 ENSMUST00000135124.1
Ogdh
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr7_+_27862557 0.008 ENSMUST00000053722.8
Zfp607
zinc finger proten 607
chr11_+_109425967 0.006 ENSMUST00000020929.9
Amz2
archaelysin family metallopeptidase 2
chrX_+_169036610 0.004 ENSMUST00000087016.4
ENSMUST00000112129.1
ENSMUST00000112131.2
Arhgap6


Rho GTPase activating protein 6


chr5_-_115119277 0.003 ENSMUST00000031524.7
Acads
acyl-Coenzyme A dehydrogenase, short chain
chr2_+_155236602 0.002 ENSMUST00000150602.1
Dynlrb1
dynein light chain roadblock-type 1
chr5_+_129895723 0.001 ENSMUST00000041466.7
ENSMUST00000077320.2
2410018M08Rik

RIKEN cDNA 2410018M08 gene

chr11_+_87109221 0.000 ENSMUST00000020794.5
Ska2
spindle and kinetochore associated complex subunit 2

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.1 GO:1903181 regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181)
0.4 1.3 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.4 1.2 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.3 0.9 GO:0003195 tricuspid valve formation(GO:0003195) right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.3 1.2 GO:2000318 positive regulation of T-helper 17 type immune response(GO:2000318)
0.3 1.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.3 3.0 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.3 0.5 GO:2000282 regulation of cellular amino acid biosynthetic process(GO:2000282)
0.3 1.0 GO:0090472 dibasic protein processing(GO:0090472)
0.3 1.5 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.3 0.8 GO:0045204 MAPK export from nucleus(GO:0045204)
0.2 0.7 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.2 1.7 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.2 1.9 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.2 1.7 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.2 0.5 GO:0021852 pyramidal neuron migration(GO:0021852)
0.2 2.8 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.1 8.6 GO:0030901 midbrain development(GO:0030901)
0.1 2.0 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.7 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 0.6 GO:0009405 pathogenesis(GO:0009405)
0.1 0.3 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.1 1.0 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.4 GO:0015825 L-serine transport(GO:0015825)
0.1 0.8 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.3 GO:2001187 natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.1 0.4 GO:0042701 progesterone secretion(GO:0042701)
0.1 2.2 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 2.7 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 0.4 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.1 1.3 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.1 2.1 GO:0071625 vocalization behavior(GO:0071625)
0.1 0.2 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 0.2 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.4 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 1.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.3 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.1 0.4 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.1 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.0 0.6 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.0 0.8 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.9 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0 0.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 1.2 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 1.3 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.1 GO:1900368 regulation of RNA interference(GO:1900368)
0.0 1.3 GO:0048246 macrophage chemotaxis(GO:0048246)
0.0 0.4 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.8 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.0 0.7 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.2 GO:0045836 positive regulation of meiotic nuclear division(GO:0045836)
0.0 0.8 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:0015744 succinate transport(GO:0015744)
0.0 0.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 1.2 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 0.4 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.0 0.1 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.0 0.0 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.0 0.4 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.1 GO:0042407 cristae formation(GO:0042407)
0.0 0.1 GO:0042538 hyperosmotic salinity response(GO:0042538)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.1 GO:0097513 myosin II filament(GO:0097513)
0.2 3.0 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 0.9 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 1.7 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 0.6 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 1.0 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 2.1 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 1.6 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.9 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.9 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 1.8 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 2.0 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 2.7 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.4 GO:0042587 glycogen granule(GO:0042587)
0.0 0.3 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.5 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.0 11.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 1.3 GO:0005871 kinesin complex(GO:0005871)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.3 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.4 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.2 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 1.5 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.0 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0031752 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.3 3.0 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.3 1.7 GO:0005042 netrin receptor activity(GO:0005042)
0.3 0.8 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.2 3.1 GO:0050897 cobalt ion binding(GO:0050897)
0.2 0.7 GO:0046997 sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.2 1.1 GO:0070728 leucine binding(GO:0070728)
0.2 0.7 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.2 0.8 GO:0015440 peptide-transporting ATPase activity(GO:0015440)
0.2 1.3 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 2.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 1.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.4 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 1.9 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.1 1.0 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.7 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.1 GO:0015172 acidic amino acid transmembrane transporter activity(GO:0015172)
0.1 0.3 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 1.3 GO:0042605 peptide antigen binding(GO:0042605)
0.1 1.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 0.2 GO:0004568 chitinase activity(GO:0004568)
0.1 0.4 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.1 1.2 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 0.6 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.2 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.3 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.5 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 2.2 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.1 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.6 GO:0008009 chemokine activity(GO:0008009)
0.0 0.9 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.8 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.7 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 1.5 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.8 GO:0008276 protein methyltransferase activity(GO:0008276)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 2.5 PID_IL3_PATHWAY IL3-mediated signaling events
0.0 1.6 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 1.3 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 0.8 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.0 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.2 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.7 PID_BCR_5PATHWAY BCR signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 3.0 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 1.7 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.0 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 2.1 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.4 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 2.3 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.4 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.3 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.3 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.3 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.1 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.1 REACTOME_MICRORNA_MIRNA_BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.4 REACTOME_ENOS_ACTIVATION_AND_REGULATION Genes involved in eNOS activation and regulation
0.0 0.5 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.1 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol