Motif ID: Spdef

Z-value: 0.472


Transcription factors associated with Spdef:

Gene SymbolEntrez IDGene Name
Spdef ENSMUSG00000024215.7 Spdef

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Spdefmm10_v2_chr17_-_27728889_277289560.029.1e-01Click!


Activity profile for motif Spdef.

activity profile for motif Spdef


Sorted Z-values histogram for motif Spdef

Sorted Z-values for motif Spdef



Network of associatons between targets according to the STRING database.



First level regulatory network of Spdef

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_58813359 3.244 ENSMUST00000135526.2
ENSMUST00000153031.1
Sh3rf3

SH3 domain containing ring finger 3

chr18_+_34861200 1.692 ENSMUST00000165033.1
Egr1
early growth response 1
chr14_-_70207637 1.461 ENSMUST00000022682.5
Sorbs3
sorbin and SH3 domain containing 3
chr11_-_55419898 1.156 ENSMUST00000108858.1
ENSMUST00000141530.1
Sparc

secreted acidic cysteine rich glycoprotein

chr15_-_89170688 0.996 ENSMUST00000060808.9
Plxnb2
plexin B2
chr2_-_167492826 0.984 ENSMUST00000109211.2
ENSMUST00000057627.9
Spata2

spermatogenesis associated 2

chr14_+_28511344 0.940 ENSMUST00000112272.1
Wnt5a
wingless-related MMTV integration site 5A
chr14_+_54254124 0.926 ENSMUST00000180359.1
Abhd4
abhydrolase domain containing 4
chrX_+_110814390 0.922 ENSMUST00000078229.3
Pou3f4
POU domain, class 3, transcription factor 4
chr17_+_88626569 0.918 ENSMUST00000150023.1
Ston1
stonin 1
chr9_+_65908967 0.880 ENSMUST00000034949.3
ENSMUST00000154589.1
Csnk1g1

casein kinase 1, gamma 1

chr3_-_90243073 0.879 ENSMUST00000107369.1
Creb3l4
cAMP responsive element binding protein 3-like 4
chr13_-_60177357 0.864 ENSMUST00000065086.4
Gas1
growth arrest specific 1
chr9_+_80165079 0.858 ENSMUST00000184480.1
Myo6
myosin VI
chr5_+_66968961 0.844 ENSMUST00000132991.1
Limch1
LIM and calponin homology domains 1
chr5_+_66968559 0.839 ENSMUST00000127184.1
Limch1
LIM and calponin homology domains 1
chr2_+_62664279 0.823 ENSMUST00000028257.2
Gca
grancalcin
chr3_-_84582616 0.817 ENSMUST00000143514.1
Arfip1
ADP-ribosylation factor interacting protein 1
chrX_+_101254528 0.752 ENSMUST00000062000.4
Foxo4
forkhead box O4
chrX_-_134276888 0.735 ENSMUST00000113252.1
Trmt2b
TRM2 tRNA methyltransferase 2B
chrX_-_134276969 0.732 ENSMUST00000087541.5
ENSMUST00000087540.3
Trmt2b

TRM2 tRNA methyltransferase 2B

chr13_+_40886758 0.727 ENSMUST00000069958.7
Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr15_-_99820072 0.724 ENSMUST00000109024.2
Lima1
LIM domain and actin binding 1
chr13_-_19619820 0.709 ENSMUST00000002885.6
Epdr1
ependymin related protein 1 (zebrafish)
chr9_-_65908676 0.705 ENSMUST00000119245.1
ENSMUST00000134338.1
ENSMUST00000179395.1
Trip4


thyroid hormone receptor interactor 4


chr9_+_30427329 0.693 ENSMUST00000164099.1
Snx19
sorting nexin 19
chr3_-_84582476 0.691 ENSMUST00000107687.2
ENSMUST00000098990.3
Arfip1

ADP-ribosylation factor interacting protein 1

chr13_+_12395362 0.685 ENSMUST00000059270.8
Heatr1
HEAT repeat containing 1
chr9_+_80165013 0.679 ENSMUST00000035889.8
ENSMUST00000113268.1
Myo6

myosin VI

chr1_-_56969864 0.670 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr12_-_85339346 0.662 ENSMUST00000040992.7
Nek9
NIMA (never in mitosis gene a)-related expressed kinase 9
chr13_-_21531032 0.662 ENSMUST00000156674.2
ENSMUST00000110481.2
Zkscan8

zinc finger with KRAB and SCAN domains 8

chr8_+_125995102 0.658 ENSMUST00000046765.8
Kcnk1
potassium channel, subfamily K, member 1
chr12_-_102878406 0.638 ENSMUST00000045652.6
Btbd7
BTB (POZ) domain containing 7
chr5_+_66968416 0.627 ENSMUST00000038188.7
Limch1
LIM and calponin homology domains 1
chr1_-_56969827 0.624 ENSMUST00000176759.1
Satb2
special AT-rich sequence binding protein 2
chr11_-_119355484 0.615 ENSMUST00000100172.2
ENSMUST00000005173.4
Sgsh

N-sulfoglucosamine sulfohydrolase (sulfamidase)

chr4_+_156203292 0.600 ENSMUST00000105140.2
AW011738
expressed sequence AW011738
chr10_-_58675631 0.597 ENSMUST00000003312.4
Edar
ectodysplasin-A receptor
chr10_-_93311073 0.587 ENSMUST00000008542.5
Elk3
ELK3, member of ETS oncogene family
chr7_+_127841752 0.579 ENSMUST00000033075.7
Stx4a
syntaxin 4A (placental)
chr7_+_127841817 0.576 ENSMUST00000121705.1
Stx4a
syntaxin 4A (placental)
chr11_-_94474088 0.575 ENSMUST00000107786.1
ENSMUST00000107791.1
ENSMUST00000103166.2
ENSMUST00000107792.1
ENSMUST00000100561.3
ENSMUST00000107793.1
ENSMUST00000107788.1
ENSMUST00000107790.1
ENSMUST00000107789.1
ENSMUST00000107785.1
ENSMUST00000021234.8
Cacna1g










calcium channel, voltage-dependent, T type, alpha 1G subunit










chr11_+_60777525 0.571 ENSMUST00000056907.6
ENSMUST00000102667.3
Smcr8

Smith-Magenis syndrome chromosome region, candidate 8 homolog (human)

chrX_-_102505359 0.559 ENSMUST00000087916.4
Hdac8
histone deacetylase 8
chr1_+_61638819 0.540 ENSMUST00000138768.1
ENSMUST00000075374.3
Pard3b

par-3 partitioning defective 3 homolog B (C. elegans)

chr2_-_26445175 0.534 ENSMUST00000114082.2
ENSMUST00000091252.4
Sec16a

SEC16 homolog A (S. cerevisiae)

chr17_-_84466186 0.529 ENSMUST00000047524.8
Thada
thyroid adenoma associated
chr11_-_60777241 0.496 ENSMUST00000120417.1
ENSMUST00000102668.3
ENSMUST00000117743.1
ENSMUST00000130068.1
ENSMUST00000002891.4
Top3a




topoisomerase (DNA) III alpha




chr16_-_44016387 0.495 ENSMUST00000036174.3
Gramd1c
GRAM domain containing 1C
chr7_+_127876796 0.492 ENSMUST00000131000.1
Zfp646
zinc finger protein 646
chr3_+_27938638 0.491 ENSMUST00000120834.1
Pld1
phospholipase D1
chr8_+_113635550 0.491 ENSMUST00000179926.1
Mon1b
MON1 homolog b (yeast)
chr2_-_18392736 0.477 ENSMUST00000091418.5
ENSMUST00000166495.1
Dnajc1

DnaJ (Hsp40) homolog, subfamily C, member 1

chr1_-_13589717 0.463 ENSMUST00000027068.4
Tram1
translocating chain-associating membrane protein 1
chr2_+_106693185 0.459 ENSMUST00000111063.1
Mpped2
metallophosphoesterase domain containing 2
chr9_+_45055166 0.457 ENSMUST00000114664.1
ENSMUST00000093856.3
Mpzl3

myelin protein zero-like 3

chr6_-_86793522 0.457 ENSMUST00000001187.8
Anxa4
annexin A4
chr14_+_54936456 0.446 ENSMUST00000037814.6
Cmtm5
CKLF-like MARVEL transmembrane domain containing 5
chr8_+_113635787 0.442 ENSMUST00000035777.8
Mon1b
MON1 homolog b (yeast)
chrX_+_6577259 0.441 ENSMUST00000089520.2
Shroom4
shroom family member 4
chr2_+_32151074 0.432 ENSMUST00000036691.7
ENSMUST00000069817.8
Prrc2b

proline-rich coiled-coil 2B

chr1_+_58802492 0.429 ENSMUST00000165549.1
Casp8
caspase 8
chr8_-_69996326 0.427 ENSMUST00000177851.1
ENSMUST00000065169.4
Gatad2a

GATA zinc finger domain containing 2A

chr6_-_30509706 0.421 ENSMUST00000064330.6
ENSMUST00000102991.2
ENSMUST00000115157.1
ENSMUST00000148638.1
Tmem209



transmembrane protein 209



chr17_-_35074485 0.419 ENSMUST00000007259.3
Ly6g6d
lymphocyte antigen 6 complex, locus G6D
chr3_+_135825788 0.413 ENSMUST00000167390.1
Slc39a8
solute carrier family 39 (metal ion transporter), member 8
chr15_-_36608959 0.408 ENSMUST00000001809.8
Pabpc1
poly(A) binding protein, cytoplasmic 1
chr7_+_101378183 0.402 ENSMUST00000084895.5
Arap1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr11_-_83302586 0.395 ENSMUST00000176374.1
Pex12
peroxisomal biogenesis factor 12
chr18_+_12643329 0.392 ENSMUST00000025294.7
Ttc39c
tetratricopeptide repeat domain 39C
chr6_-_119388671 0.391 ENSMUST00000169744.1
Adipor2
adiponectin receptor 2
chr5_-_69592274 0.388 ENSMUST00000174233.1
ENSMUST00000120789.1
ENSMUST00000166298.1
Gnpda2


glucosamine-6-phosphate deaminase 2


chr5_+_105732063 0.385 ENSMUST00000154807.1
Lrrc8d
leucine rich repeat containing 8D
chr12_+_102283036 0.385 ENSMUST00000056950.7
Rin3
Ras and Rab interactor 3
chr8_+_109778554 0.385 ENSMUST00000093157.6
Ap1g1
adaptor protein complex AP-1, gamma 1 subunit
chr5_+_138085083 0.384 ENSMUST00000019660.4
ENSMUST00000066617.5
ENSMUST00000110963.1
Zkscan1


zinc finger with KRAB and SCAN domains 1


chr18_-_46597299 0.382 ENSMUST00000036030.7
Tmed7
transmembrane emp24 protein transport domain containing 7
chr9_+_32224457 0.381 ENSMUST00000183121.1
Arhgap32
Rho GTPase activating protein 32
chr8_-_110846770 0.381 ENSMUST00000042012.5
Sf3b3
splicing factor 3b, subunit 3
chr19_-_29047847 0.380 ENSMUST00000025696.4
Ak3
adenylate kinase 3
chr3_-_89393294 0.372 ENSMUST00000142119.1
ENSMUST00000029677.8
ENSMUST00000148361.1
Zbtb7b


zinc finger and BTB domain containing 7B


chr2_-_160872985 0.371 ENSMUST00000109460.1
ENSMUST00000127201.1
Zhx3

zinc fingers and homeoboxes 3

chr11_+_105126425 0.365 ENSMUST00000021030.7
Mettl2
methyltransferase like 2
chr4_-_43562397 0.364 ENSMUST00000030187.7
Tln1
talin 1
chr5_+_111733924 0.362 ENSMUST00000180627.1
Gm26897
predicted gene, 26897
chr7_+_27591705 0.360 ENSMUST00000167435.1
Akt2
thymoma viral proto-oncogene 2
chr17_+_26676390 0.360 ENSMUST00000015719.8
Atp6v0e
ATPase, H+ transporting, lysosomal V0 subunit E
chr8_+_109778863 0.351 ENSMUST00000034171.8
Ap1g1
adaptor protein complex AP-1, gamma 1 subunit
chr11_+_83302817 0.348 ENSMUST00000142680.1
Ap2b1
adaptor-related protein complex 2, beta 1 subunit
chr5_+_129941949 0.345 ENSMUST00000051758.7
ENSMUST00000073945.4
Vkorc1l1

vitamin K epoxide reductase complex, subunit 1-like 1

chr13_+_40859768 0.345 ENSMUST00000110191.2
Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr12_+_80644212 0.345 ENSMUST00000085245.5
Slc39a9
solute carrier family 39 (zinc transporter), member 9
chr5_-_146221391 0.336 ENSMUST00000161574.1
Rnf6
ring finger protein (C3H2C3 type) 6
chr3_+_96576984 0.333 ENSMUST00000148290.1
Gm16253
predicted gene 16253
chr11_+_83299005 0.330 ENSMUST00000176944.1
Ap2b1
adaptor-related protein complex 2, beta 1 subunit
chr2_+_127208358 0.327 ENSMUST00000103220.3
Snrnp200
small nuclear ribonucleoprotein 200 (U5)
chr8_-_105568298 0.325 ENSMUST00000005849.5
Agrp
agouti related protein
chr11_+_102189620 0.324 ENSMUST00000070334.3
ENSMUST00000078975.7
G6pc3

glucose 6 phosphatase, catalytic, 3

chr6_+_29348069 0.323 ENSMUST00000173216.1
ENSMUST00000031779.10
ENSMUST00000090481.7
Calu


calumenin


chr17_-_32947372 0.321 ENSMUST00000139353.1
Cyp4f13
cytochrome P450, family 4, subfamily f, polypeptide 13
chr18_+_36783222 0.316 ENSMUST00000019287.8
Hars2
histidyl-tRNA synthetase 2, mitochondrial (putative)
chr11_-_103412668 0.315 ENSMUST00000041272.9
Plekhm1
pleckstrin homology domain containing, family M (with RUN domain) member 1
chr19_+_6306456 0.313 ENSMUST00000025681.7
Cdc42bpg
CDC42 binding protein kinase gamma (DMPK-like)
chr1_+_36307745 0.313 ENSMUST00000142319.1
ENSMUST00000097778.2
ENSMUST00000115031.1
ENSMUST00000115032.1
ENSMUST00000137906.1
ENSMUST00000115029.1
Arid5a





AT rich interactive domain 5A (MRF1-like)





chr9_+_13749291 0.308 ENSMUST00000156801.1
ENSMUST00000134530.1
Mtmr2

myotubularin related protein 2

chr17_+_28272191 0.306 ENSMUST00000169040.1
Ppard
peroxisome proliferator activator receptor delta
chr3_+_135825648 0.306 ENSMUST00000180196.1
Slc39a8
solute carrier family 39 (metal ion transporter), member 8
chr2_-_121171107 0.305 ENSMUST00000163766.1
ENSMUST00000146243.1
Zscan29

zinc finger SCAN domains 29

chr5_+_137745730 0.296 ENSMUST00000100540.3
Tsc22d4
TSC22 domain family, member 4
chr11_-_72795801 0.293 ENSMUST00000079681.5
Cyb5d2
cytochrome b5 domain containing 2
chr8_+_85840971 0.291 ENSMUST00000053771.7
ENSMUST00000161850.1
Phkb

phosphorylase kinase beta

chr2_+_145785980 0.290 ENSMUST00000110005.1
ENSMUST00000094480.4
Rin2

Ras and Rab interactor 2

chr5_+_137745967 0.290 ENSMUST00000100539.3
Tsc22d4
TSC22 domain family, member 4
chr5_+_105731755 0.289 ENSMUST00000127686.1
Lrrc8d
leucine rich repeat containing 8D
chr12_-_54999102 0.286 ENSMUST00000173529.1
Baz1a
bromodomain adjacent to zinc finger domain 1A
chr7_+_27233003 0.286 ENSMUST00000003860.6
ENSMUST00000108378.3
Adck4

aarF domain containing kinase 4

chr10_-_128547722 0.283 ENSMUST00000040572.3
Zc3h10
zinc finger CCCH type containing 10
chr5_+_124439891 0.279 ENSMUST00000059580.4
Setd8
SET domain containing (lysine methyltransferase) 8
chr11_-_75454656 0.278 ENSMUST00000173320.1
Wdr81
WD repeat domain 81
chr13_-_21531084 0.277 ENSMUST00000045228.5
Zkscan8
zinc finger with KRAB and SCAN domains 8
chr1_+_85894281 0.276 ENSMUST00000027425.9
Itm2c
integral membrane protein 2C
chrX_-_75843185 0.275 ENSMUST00000137192.1
Pls3
plastin 3 (T-isoform)
chr18_-_46597480 0.272 ENSMUST00000151189.1
Tmed7
transmembrane emp24 protein transport domain containing 7
chr7_-_109960461 0.271 ENSMUST00000080437.6
Dennd5a
DENN/MADD domain containing 5A
chr10_+_77622363 0.271 ENSMUST00000172772.1
Ube2g2
ubiquitin-conjugating enzyme E2G 2
chr17_+_26676405 0.267 ENSMUST00000167352.1
Atp6v0e
ATPase, H+ transporting, lysosomal V0 subunit E
chr10_+_17723220 0.265 ENSMUST00000038107.7
Cited2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr4_-_118409219 0.265 ENSMUST00000075406.5
Szt2
seizure threshold 2
chr2_-_160872829 0.264 ENSMUST00000176141.1
Zhx3
zinc fingers and homeoboxes 3
chr3_+_79629074 0.264 ENSMUST00000029388.8
4930579G24Rik
RIKEN cDNA 4930579G24 gene
chr4_-_107923519 0.260 ENSMUST00000106719.1
ENSMUST00000106720.2
ENSMUST00000131644.1
ENSMUST00000030345.8
Cpt2



carnitine palmitoyltransferase 2



chr7_+_130774069 0.259 ENSMUST00000048453.5
Btbd16
BTB (POZ) domain containing 16
chr7_-_109960385 0.259 ENSMUST00000106722.1
Dennd5a
DENN/MADD domain containing 5A
chr11_-_78176619 0.256 ENSMUST00000148154.2
ENSMUST00000017549.6
Nek8

NIMA (never in mitosis gene a)-related expressed kinase 8

chr4_-_4793275 0.255 ENSMUST00000084949.2
Impad1
inositol monophosphatase domain containing 1
chr12_+_17348422 0.252 ENSMUST00000046011.10
Nol10
nucleolar protein 10
chr5_+_145283343 0.252 ENSMUST00000094116.3
Zscan25
zinc finger and SCAN domain containing 25
chr5_-_146220901 0.250 ENSMUST00000169407.2
ENSMUST00000161331.1
ENSMUST00000159074.2
ENSMUST00000067837.3
Rnf6



ring finger protein (C3H2C3 type) 6



chr9_+_65032722 0.248 ENSMUST00000167773.1
Dpp8
dipeptidylpeptidase 8
chr3_+_116008220 0.247 ENSMUST00000106502.1
Extl2
exostoses (multiple)-like 2
chr4_-_130279205 0.245 ENSMUST00000120126.2
Serinc2
serine incorporator 2
chr5_+_114100308 0.233 ENSMUST00000031588.7
Usp30
ubiquitin specific peptidase 30
chr11_+_74898078 0.233 ENSMUST00000045807.7
Tsr1
TSR1 20S rRNA accumulation
chr2_+_130406478 0.230 ENSMUST00000055421.4
Tmem239
transmembrane 239
chr5_-_140830430 0.228 ENSMUST00000000153.4
Gna12
guanine nucleotide binding protein, alpha 12
chr5_-_69592311 0.225 ENSMUST00000031117.6
Gnpda2
glucosamine-6-phosphate deaminase 2
chr17_+_47140942 0.224 ENSMUST00000077951.7
Trerf1
transcriptional regulating factor 1
chr7_-_80232479 0.223 ENSMUST00000123279.1
Cib1
calcium and integrin binding 1 (calmyrin)
chr11_-_95310186 0.223 ENSMUST00000103159.3
ENSMUST00000107734.3
ENSMUST00000107733.3
Kat7


K(lysine) acetyltransferase 7


chr2_-_52742169 0.222 ENSMUST00000102759.1
ENSMUST00000127316.1
Stam2

signal transducing adaptor molecule (SH3 domain and ITAM motif) 2

chr17_+_35049966 0.221 ENSMUST00000007257.9
Clic1
chloride intracellular channel 1
chr19_+_6363719 0.220 ENSMUST00000113489.1
ENSMUST00000113488.1
Sf1

splicing factor 1

chr7_-_73537621 0.219 ENSMUST00000172704.1
Chd2
chromodomain helicase DNA binding protein 2
chr10_+_88147061 0.217 ENSMUST00000169309.1
Nup37
nucleoporin 37
chr12_+_84362029 0.215 ENSMUST00000110278.1
ENSMUST00000145522.1
Coq6

coenzyme Q6 homolog (yeast)

chr4_-_43025756 0.215 ENSMUST00000098109.2
Pigo
phosphatidylinositol glycan anchor biosynthesis, class O
chr3_-_122984404 0.214 ENSMUST00000090379.2
Usp53
ubiquitin specific peptidase 53
chr1_-_121567906 0.213 ENSMUST00000001724.5
Ddx18
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr11_+_78176711 0.210 ENSMUST00000098545.5
Tlcd1
TLC domain containing 1
chr14_-_52197216 0.210 ENSMUST00000046709.7
Supt16
suppressor of Ty 16
chr11_-_98149551 0.209 ENSMUST00000103143.3
Fbxl20
F-box and leucine-rich repeat protein 20
chr9_+_57560934 0.206 ENSMUST00000045791.9
Scamp2
secretory carrier membrane protein 2
chr10_+_88146992 0.206 ENSMUST00000052355.7
Nup37
nucleoporin 37
chr6_-_72390659 0.206 ENSMUST00000059983.9
Vamp8
vesicle-associated membrane protein 8
chr17_-_57247632 0.205 ENSMUST00000005975.6
Gpr108
G protein-coupled receptor 108
chr4_-_101265236 0.203 ENSMUST00000149297.1
ENSMUST00000102781.3
Jak1

Janus kinase 1

chr2_-_7395879 0.203 ENSMUST00000182404.1
Celf2
CUGBP, Elav-like family member 2
chr3_-_51277470 0.199 ENSMUST00000108053.2
ENSMUST00000108051.1
Elf2

E74-like factor 2

chr1_-_172082757 0.199 ENSMUST00000003550.4
Ncstn
nicastrin
chr17_+_32506446 0.196 ENSMUST00000165999.1
Cyp4f17
cytochrome P450, family 4, subfamily f, polypeptide 17
chr4_-_116627921 0.195 ENSMUST00000030456.7
Nasp
nuclear autoantigenic sperm protein (histone-binding)
chr10_-_95416850 0.195 ENSMUST00000020215.9
Socs2
suppressor of cytokine signaling 2
chr2_+_6322621 0.194 ENSMUST00000114937.1
Usp6nl
USP6 N-terminal like
chr3_-_5576233 0.193 ENSMUST00000059021.4
Pex2
peroxisomal biogenesis factor 2
chr10_-_39899238 0.192 ENSMUST00000178563.1
AA474331
expressed sequence AA474331
chr11_+_21572221 0.192 ENSMUST00000020568.3
ENSMUST00000131135.1
Wdpcp

WD repeat containing planar cell polarity effector

chr4_+_44756609 0.189 ENSMUST00000143385.1
Zcchc7
zinc finger, CCHC domain containing 7
chr3_-_79628660 0.188 ENSMUST00000120992.1
Etfdh
electron transferring flavoprotein, dehydrogenase
chr4_+_149485215 0.188 ENSMUST00000124413.1
ENSMUST00000141293.1
Lzic

leucine zipper and CTNNBIP1 domain containing

chr11_+_60454587 0.187 ENSMUST00000018568.3
Drg2
developmentally regulated GTP binding protein 2
chr13_+_77135513 0.186 ENSMUST00000168779.1
2210408I21Rik
RIKEN cDNA 2210408I21 gene
chr9_+_27299205 0.186 ENSMUST00000115247.1
ENSMUST00000133213.1
Igsf9b

immunoglobulin superfamily, member 9B

chr2_-_52742142 0.183 ENSMUST00000138290.1
Stam2
signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
chr11_+_72796254 0.183 ENSMUST00000069395.5
Zzef1
zinc finger, ZZ-type with EF hand domain 1
chr18_-_60848911 0.182 ENSMUST00000177172.1
ENSMUST00000175934.1
ENSMUST00000176630.1
Tcof1


Treacher Collins Franceschetti syndrome 1, homolog


chr6_-_57692007 0.181 ENSMUST00000053386.5
ENSMUST00000185014.1
Pyurf
PYURF
Pigy upstream reading frame
protein preY, mitochondrial precursor
chrX_+_134686519 0.176 ENSMUST00000124226.2
Armcx4
armadillo repeat containing, X-linked 4
chr7_-_28372597 0.174 ENSMUST00000144700.1
Plekhg2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr19_-_7295394 0.174 ENSMUST00000025921.8
Mark2
MAP/microtubule affinity-regulating kinase 2
chr1_+_51987139 0.172 ENSMUST00000168302.1
Stat4
signal transducer and activator of transcription 4
chr12_+_76072016 0.171 ENSMUST00000131480.1
Syne2
spectrin repeat containing, nuclear envelope 2
chr14_+_55591708 0.169 ENSMUST00000019443.8
Rnf31
ring finger protein 31
chr9_+_122888471 0.166 ENSMUST00000063980.6
Zkscan7
zinc finger with KRAB and SCAN domains 7
chr19_-_6840590 0.163 ENSMUST00000170516.2
ENSMUST00000025903.5
Rps6ka4

ribosomal protein S6 kinase, polypeptide 4

chr10_-_86011833 0.163 ENSMUST00000105304.1
ENSMUST00000061699.5
Bpifc

BPI fold containing family C

chr3_-_79628859 0.162 ENSMUST00000029386.7
Etfdh
electron transferring flavoprotein, dehydrogenase
chrX_-_57338598 0.162 ENSMUST00000033468.4
ENSMUST00000114736.1
Arhgef6

Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6

chr1_+_95313607 0.161 ENSMUST00000059975.6
Fam174a
family with sequence similarity 174, member A
chr11_+_117232254 0.160 ENSMUST00000106354.2
Sept9
septin 9

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0072223 metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
0.4 1.2 GO:0002447 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308) regulation of eosinophil activation(GO:1902566)
0.3 0.9 GO:0061349 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) hypophysis morphogenesis(GO:0048850) cervix development(GO:0060067) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354)
0.3 0.9 GO:0019085 early viral transcription(GO:0019085)
0.2 0.7 GO:0043323 positive regulation of natural killer cell degranulation(GO:0043323)
0.2 0.6 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.2 0.6 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.2 1.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.7 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 0.6 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.1 0.4 GO:0002946 tRNA C5-cytosine methylation(GO:0002946)
0.1 0.3 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 0.7 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 1.5 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.1 0.7 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.1 0.3 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.4 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.1 0.9 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.1 0.8 GO:0070317 negative regulation of smooth muscle cell differentiation(GO:0051151) negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.8 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.4 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.6 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 1.3 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 0.9 GO:0042473 outer ear morphogenesis(GO:0042473)
0.1 0.3 GO:2000318 positive regulation of T-helper 17 type immune response(GO:2000318)
0.1 0.2 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.1 0.3 GO:0006776 vitamin A metabolic process(GO:0006776)
0.1 0.5 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.1 0.6 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1 0.2 GO:0072720 response to sorbitol(GO:0072708) response to dithiothreitol(GO:0072720)
0.1 1.6 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.1 0.7 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1 0.4 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.1 0.5 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 0.2 GO:0090187 zymogen granule exocytosis(GO:0070625) positive regulation of pancreatic juice secretion(GO:0090187)
0.1 0.1 GO:0072076 formation of anatomical boundary(GO:0048859) nephrogenic mesenchyme development(GO:0072076)
0.1 0.3 GO:0061428 embryonic heart tube left/right pattern formation(GO:0060971) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.1 0.3 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.1 0.6 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.2 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.1 0.4 GO:0006172 ADP biosynthetic process(GO:0006172)
0.1 0.5 GO:0006265 DNA topological change(GO:0006265)
0.1 0.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.4 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.1 0.2 GO:2000256 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163) positive regulation of male germ cell proliferation(GO:2000256)
0.1 0.2 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 0.6 GO:0060693 regulation of branching involved in salivary gland morphogenesis(GO:0060693)
0.1 0.4 GO:2001185 regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.1 0.5 GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471)
0.1 0.1 GO:0032817 regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819)
0.1 0.2 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.0 0.1 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.1 GO:2000850 negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.0 0.3 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.4 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.3 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.1 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.8 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.3 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.2 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.4 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.1 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
0.0 0.1 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.3 GO:0061042 vascular wound healing(GO:0061042)
0.0 0.2 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.2 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.6 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.3 GO:0006691 leukotriene metabolic process(GO:0006691)
0.0 0.1 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.1 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.2 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.0 0.2 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 1.1 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.0 0.1 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.0 0.4 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.3 GO:0030238 male sex determination(GO:0030238)
0.0 0.2 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.1 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.0 1.0 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.1 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.1 GO:0021764 amygdala development(GO:0021764)
0.0 0.2 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.4 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.2 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151)
0.0 0.2 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.0 0.7 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.0 0.2 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.1 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.1 GO:0018202 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) peptidyl-histidine modification(GO:0018202)
0.0 0.3 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.4 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 0.3 GO:0060749 mammary gland alveolus development(GO:0060749) mammary gland lobule development(GO:0061377)
0.0 0.1 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.5 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.2 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.1 GO:0018342 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0 0.6 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.0 GO:0006105 succinate metabolic process(GO:0006105)
0.0 1.5 GO:0008033 tRNA processing(GO:0008033)
0.0 0.2 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.3 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.5 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.6 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.0 0.1 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.6 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.3 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.0 0.3 GO:0002063 chondrocyte development(GO:0002063)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.2 1.2 GO:0000322 storage vacuole(GO:0000322)
0.2 0.7 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 0.4 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.1 0.5 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.1 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.4 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.1 0.3 GO:0097543 ciliary inversin compartment(GO:0097543)
0.1 0.3 GO:0008623 CHRAC(GO:0008623)
0.1 0.2 GO:0035101 FACT complex(GO:0035101)
0.1 0.6 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 0.6 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 1.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 1.4 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 0.3 GO:0005796 Golgi lumen(GO:0005796)
0.1 1.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.3 GO:1990130 Iml1 complex(GO:1990130)
0.1 0.6 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.1 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 2.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.4 GO:0016460 myosin II complex(GO:0016460)
0.0 0.8 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.5 GO:0030904 retromer complex(GO:0030904)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.6 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.8 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.3 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 1.3 GO:0032432 actin filament bundle(GO:0032432)
0.0 1.1 GO:0016605 PML body(GO:0016605)
0.0 0.0 GO:0000801 central element(GO:0000801)
0.0 0.2 GO:0044447 axoneme part(GO:0044447)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.4 1.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.3 0.9 GO:0005110 frizzled-2 binding(GO:0005110)
0.3 1.2 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.2 1.5 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 0.6 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.6 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.4 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 0.4 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 0.6 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.1 1.8 GO:0017166 vinculin binding(GO:0017166)
0.1 0.4 GO:0035877 death effector domain binding(GO:0035877)
0.1 0.3 GO:0016501 prostacyclin receptor activity(GO:0016501)
0.1 0.5 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 0.4 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.1 0.4 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.2 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.1 0.3 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 1.0 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.5 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 0.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.2 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 0.2 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 0.2 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.1 0.3 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 0.7 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.2 GO:0051747 cytosine C-5 DNA demethylase activity(GO:0051747)
0.1 0.3 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.4 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.4 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.5 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.0 1.5 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.2 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.6 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.3 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.4 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.6 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.3 GO:0048038 quinone binding(GO:0048038)
0.0 2.0 GO:0005518 collagen binding(GO:0005518)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.7 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.6 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.3 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.3 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 1.0 GO:0050681 androgen receptor binding(GO:0050681)
0.0 1.0 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.5 GO:0071949 FAD binding(GO:0071949)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.1 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.2 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.0 GO:0016635 succinate dehydrogenase (ubiquinone) activity(GO:0008177) oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.5 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 2.0 GO:0051015 actin filament binding(GO:0051015)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.0 1.5 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.0 0.4 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.6 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 0.4 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.0 0.9 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.0 0.9 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 1.5 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.8 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.5 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 0.7 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.2 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 0.4 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 0.6 PID_ATM_PATHWAY ATM pathway
0.0 0.3 PID_ARF_3PATHWAY Arf1 pathway
0.0 0.1 PID_ALK2_PATHWAY ALK2 signaling events
0.0 0.7 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.4 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.0 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 0.2 PID_IL27_PATHWAY IL27-mediated signaling events
0.0 0.2 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 1.5 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.1 0.8 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 1.8 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.8 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.7 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.6 REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.1 REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.6 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.0 0.4 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.8 REACTOME_PIP3_ACTIVATES_AKT_SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.3 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.9 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.0 0.3 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.2 REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.2 REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.5 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.3 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.1 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.1 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.6 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.1 REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRONLESS_TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.1 REACTOME_G_ALPHA1213_SIGNALLING_EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.5 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway