Motif ID: Neurod2_Bhlha15_Bhlhe22_Olig1

Z-value: 0.569


Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bhlhe22mm10_v2_chr3_+_18054258_180543250.594.6e-05Click!
Neurod2mm10_v2_chr11_-_98329641_983296540.551.8e-04Click!
Olig1mm10_v2_chr16_+_91269759_91269778-0.086.2e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Neurod2_Bhlha15_Bhlhe22_Olig1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_43235856 3.793 ENSMUST00000146708.1
Zbtb20
zinc finger and BTB domain containing 20
chr17_-_36989504 3.417 ENSMUST00000169189.1
H2-M5
histocompatibility 2, M region locus 5
chr3_-_120886691 2.762 ENSMUST00000182099.1
ENSMUST00000183168.1
ENSMUST00000183276.1
ENSMUST00000182124.1
6530403H02Rik



RIKEN cDNA 6530403H02 gene



chr5_+_124194894 2.604 ENSMUST00000159053.1
ENSMUST00000162577.1
Gm16338

predicted gene 16338

chr10_-_25200110 2.322 ENSMUST00000100012.2
Akap7
A kinase (PRKA) anchor protein 7
chr1_-_111864869 2.112 ENSMUST00000035462.5
Dsel
dermatan sulfate epimerase-like
chr1_-_150392719 2.040 ENSMUST00000006167.6
ENSMUST00000094477.2
ENSMUST00000097547.3
BC003331


cDNA sequence BC003331


chr1_+_177444653 1.984 ENSMUST00000094276.3
Zbtb18
zinc finger and BTB domain containing 18
chr4_-_42034726 1.889 ENSMUST00000084677.2
Gm21093
predicted gene, 21093
chr5_-_66618772 1.791 ENSMUST00000162994.1
ENSMUST00000159512.1
ENSMUST00000159786.1
Apbb2


amyloid beta (A4) precursor protein-binding, family B, member 2


chr4_-_141598206 1.747 ENSMUST00000131317.1
ENSMUST00000006381.4
ENSMUST00000129602.1
Fblim1


filamin binding LIM protein 1


chr5_-_66618636 1.733 ENSMUST00000162382.1
ENSMUST00000160870.1
ENSMUST00000087256.5
ENSMUST00000160103.1
ENSMUST00000162349.1
Apbb2




amyloid beta (A4) precursor protein-binding, family B, member 2




chr1_+_15287259 1.730 ENSMUST00000175681.1
Kcnb2
potassium voltage gated channel, Shab-related subfamily, member 2
chr2_+_65930117 1.660 ENSMUST00000176109.1
Csrnp3
cysteine-serine-rich nuclear protein 3
chr2_+_69670100 1.612 ENSMUST00000100050.3
Klhl41
kelch-like 41
chr2_-_79456750 1.571 ENSMUST00000041099.4
Neurod1
neurogenic differentiation 1
chr9_+_72985568 1.435 ENSMUST00000150826.2
ENSMUST00000085350.4
ENSMUST00000140675.1
Ccpg1


cell cycle progression 1


chr9_-_21918089 1.433 ENSMUST00000128442.1
ENSMUST00000119055.1
ENSMUST00000122211.1
ENSMUST00000115351.3
Rab3d



RAB3D, member RAS oncogene family



chr19_-_37176055 1.383 ENSMUST00000142973.1
ENSMUST00000154376.1
Cpeb3

cytoplasmic polyadenylation element binding protein 3

chr1_-_44218952 1.338 ENSMUST00000054801.3
Mettl21e
methyltransferase like 21E
chr1_+_150392794 1.320 ENSMUST00000124973.2
Tpr
translocated promoter region
chr13_-_62607499 1.308 ENSMUST00000091563.4
6720489N17Rik
RIKEN cDNA 6720489N17 gene
chr11_+_58954675 1.285 ENSMUST00000047697.5
ENSMUST00000108817.3
Trim17
Hist3h2a
tripartite motif-containing 17
histone cluster 3, H2a
chr3_-_126998408 1.263 ENSMUST00000182764.1
ENSMUST00000044443.8
Ank2

ankyrin 2, brain

chr2_+_62046580 1.255 ENSMUST00000054484.8
Slc4a10
solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
chr1_+_177445660 1.231 ENSMUST00000077225.6
Zbtb18
zinc finger and BTB domain containing 18
chr2_+_62046623 1.218 ENSMUST00000112480.2
Slc4a10
solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
chr9_+_72985504 1.188 ENSMUST00000156879.1
Ccpg1
cell cycle progression 1
chr3_+_138065052 1.186 ENSMUST00000163080.2
1110002E22Rik
RIKEN cDNA 1110002E22 gene
chr5_-_103977360 1.113 ENSMUST00000048118.8
Hsd17b13
hydroxysteroid (17-beta) dehydrogenase 13
chr2_+_62046462 1.099 ENSMUST00000102735.3
Slc4a10
solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
chr11_+_31872100 1.018 ENSMUST00000020543.6
ENSMUST00000109412.2
Cpeb4

cytoplasmic polyadenylation element binding protein 4

chr17_-_6449571 1.003 ENSMUST00000180035.1
Tmem181b-ps
transmembrane protein 181B, pseudogene
chr4_+_42035113 0.997 ENSMUST00000098127.1
Gm10597
predicted gene 10597
chr10_-_127041513 0.974 ENSMUST00000116231.2
Mettl21b
methyltransferase like 21B
chr1_-_155232710 0.891 ENSMUST00000035914.3
BC034090
cDNA sequence BC034090
chr7_+_55794146 0.868 ENSMUST00000032627.3
Tubgcp5
tubulin, gamma complex associated protein 5
chr8_+_33428709 0.867 ENSMUST00000059351.7
5930422O12Rik
RIKEN cDNA 5930422O12 gene
chr2_+_155382186 0.826 ENSMUST00000134218.1
Trp53inp2
transformation related protein 53 inducible nuclear protein 2
chr19_+_26748268 0.774 ENSMUST00000175791.1
ENSMUST00000176698.1
ENSMUST00000177252.1
ENSMUST00000176475.1
ENSMUST00000112637.2
Smarca2




SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2




chr2_-_29253001 0.770 ENSMUST00000071201.4
Ntng2
netrin G2
chr10_+_127759721 0.754 ENSMUST00000073639.5
Rdh1
retinol dehydrogenase 1 (all trans)
chr11_-_75796048 0.734 ENSMUST00000021209.7
Doc2b
double C2, beta
chr8_+_25602236 0.721 ENSMUST00000146919.1
ENSMUST00000142395.1
ENSMUST00000139966.1
Whsc1l1


Wolf-Hirschhorn syndrome candidate 1-like 1 (human)


chr4_-_108301045 0.706 ENSMUST00000043616.6
Zyg11b
zyg-ll family member B, cell cycle regulator
chr5_+_105415738 0.694 ENSMUST00000112707.1
Lrrc8b
leucine rich repeat containing 8 family, member B
chr17_-_6621267 0.654 ENSMUST00000115772.3
Tmem181c-ps
transmembrane protein 181C, pseudogene
chr19_+_26753588 0.647 ENSMUST00000177116.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr3_-_26133734 0.643 ENSMUST00000108308.3
ENSMUST00000075054.4
Nlgn1

neuroligin 1

chr9_+_72985410 0.640 ENSMUST00000037977.8
Ccpg1
cell cycle progression 1
chr6_+_51544513 0.617 ENSMUST00000179365.1
ENSMUST00000114439.1
Snx10

sorting nexin 10

chr13_-_97747399 0.617 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr8_+_25601591 0.611 ENSMUST00000155861.1
Whsc1l1
Wolf-Hirschhorn syndrome candidate 1-like 1 (human)
chr16_-_57292845 0.598 ENSMUST00000023434.8
ENSMUST00000120112.1
ENSMUST00000119407.1
Tmem30c


transmembrane protein 30C


chrX_+_159708593 0.593 ENSMUST00000080394.6
Sh3kbp1
SH3-domain kinase binding protein 1
chr8_-_106337987 0.591 ENSMUST00000067512.7
Smpd3
sphingomyelin phosphodiesterase 3, neutral
chr10_+_74967164 0.561 ENSMUST00000037813.4
Gnaz
guanine nucleotide binding protein, alpha z subunit
chr9_-_49798905 0.557 ENSMUST00000114476.2
Ncam1
neural cell adhesion molecule 1
chr8_+_104170513 0.555 ENSMUST00000171018.1
ENSMUST00000167633.1
ENSMUST00000093245.5
ENSMUST00000164076.1
Bean1



brain expressed, associated with Nedd4, 1



chrX_-_43167817 0.549 ENSMUST00000115058.1
ENSMUST00000115059.1
Tenm1

teneurin transmembrane protein 1

chr11_-_98329641 0.548 ENSMUST00000041685.6
Neurod2
neurogenic differentiation 2
chr4_+_42459563 0.538 ENSMUST00000098119.2
Gm3883
predicted gene 3883
chr5_+_129096740 0.533 ENSMUST00000056617.7
ENSMUST00000156437.1
Gpr133

G protein-coupled receptor 133

chr6_-_122340499 0.522 ENSMUST00000160843.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr15_-_76918010 0.521 ENSMUST00000048854.7
Zfp647
zinc finger protein 647
chr5_-_66618752 0.510 ENSMUST00000162366.1
Apbb2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr14_-_5449039 0.503 ENSMUST00000180143.1
Gm3194
predicted gene 3194
chr14_-_5801530 0.503 ENSMUST00000178414.1
Gm3383
predicted gene 3383
chrX_+_56454871 0.498 ENSMUST00000039374.2
ENSMUST00000101553.2
Ddx26b

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

chr18_+_69593361 0.487 ENSMUST00000114978.2
ENSMUST00000114977.1
Tcf4

transcription factor 4

chr16_-_34095983 0.484 ENSMUST00000114973.1
ENSMUST00000114964.1
Kalrn

kalirin, RhoGEF kinase

chr3_+_118430299 0.477 ENSMUST00000180774.1
Gm26871
predicted gene, 26871
chr15_-_76126538 0.475 ENSMUST00000054022.5
ENSMUST00000089654.3
BC024139

cDNA sequence BC024139

chr9_+_66350465 0.475 ENSMUST00000042824.6
Herc1
hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1
chr16_-_17722879 0.471 ENSMUST00000080936.6
ENSMUST00000012259.7
Med15

mediator complex subunit 15

chr5_-_137600650 0.464 ENSMUST00000111007.1
ENSMUST00000133705.1
Mospd3

motile sperm domain containing 3

chr3_-_84259812 0.456 ENSMUST00000107691.1
Trim2
tripartite motif-containing 2
chr13_-_101692624 0.454 ENSMUST00000035532.6
Pik3r1
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)
chr6_-_12749193 0.453 ENSMUST00000046121.6
ENSMUST00000172356.1
Thsd7a

thrombospondin, type I, domain containing 7A

chr6_-_48708206 0.421 ENSMUST00000119315.1
ENSMUST00000053661.4
Gimap6

GTPase, IMAP family member 6

chr4_+_9269285 0.420 ENSMUST00000038841.7
Clvs1
clavesin 1
chr5_-_137601043 0.406 ENSMUST00000037620.7
ENSMUST00000154708.1
Mospd3

motile sperm domain containing 3

chr16_-_46010212 0.400 ENSMUST00000130481.1
Plcxd2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr10_+_127420334 0.379 ENSMUST00000171434.1
R3hdm2
R3H domain containing 2
chr4_-_41870612 0.379 ENSMUST00000179680.1
Gm21966
predicted gene, 21966
chr10_-_12923075 0.370 ENSMUST00000180529.1
B230208H11Rik
RIKEN cDNA B230208H11 gene
chr16_+_11008898 0.368 ENSMUST00000180624.1
Gm4262
predicted gene 4262
chr3_-_27710413 0.367 ENSMUST00000046157.4
Fndc3b
fibronectin type III domain containing 3B
chr2_-_121807024 0.367 ENSMUST00000138157.1
Frmd5
FERM domain containing 5
chr8_-_69749938 0.358 ENSMUST00000130458.1
ENSMUST00000154063.1
Zfp963

zinc finger protein 963

chr4_-_108032069 0.340 ENSMUST00000106709.2
Podn
podocan
chr9_+_87015537 0.325 ENSMUST00000058846.4
Ripply2
ripply2 homolog (zebrafish)
chr18_+_55057557 0.324 ENSMUST00000181765.1
Gm4221
predicted gene 4221
chr14_+_12284198 0.316 ENSMUST00000112669.3
ENSMUST00000163392.1
3830406C13Rik

RIKEN cDNA 3830406C13 gene

chr15_-_91191733 0.302 ENSMUST00000069511.6
Abcd2
ATP-binding cassette, sub-family D (ALD), member 2
chr11_+_53433299 0.299 ENSMUST00000018382.6
Gdf9
growth differentiation factor 9
chr4_+_43441939 0.298 ENSMUST00000060864.6
Tesk1
testis specific protein kinase 1
chr2_-_130638094 0.296 ENSMUST00000089561.3
ENSMUST00000110260.1
Lzts3

leucine zipper, putative tumor suppressor family member 3

chr11_-_69602741 0.293 ENSMUST00000138694.1
Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr4_-_42459176 0.283 ENSMUST00000098118.1
Gm10597
predicted gene 10597
chr17_-_24443077 0.274 ENSMUST00000119932.1
Dnase1l2
deoxyribonuclease 1-like 2
chr8_+_4243264 0.262 ENSMUST00000110996.1
Map2k7
mitogen-activated protein kinase kinase 7
chr11_-_68853019 0.256 ENSMUST00000108672.1
Ndel1
nuclear distribution gene E-like homolog 1 (A. nidulans)
chr4_+_42714926 0.229 ENSMUST00000178454.1
Gm21955
predicted gene, 21955
chr6_-_122340200 0.229 ENSMUST00000159384.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr16_-_59553970 0.228 ENSMUST00000139989.1
Crybg3
beta-gamma crystallin domain containing 3
chr15_+_99972780 0.224 ENSMUST00000100206.2
Larp4
La ribonucleoprotein domain family, member 4
chr13_-_67332525 0.218 ENSMUST00000168892.1
ENSMUST00000109735.2
Zfp595

zinc finger protein 595

chr17_-_24443093 0.218 ENSMUST00000088506.5
Dnase1l2
deoxyribonuclease 1-like 2
chr15_+_98167806 0.215 ENSMUST00000031914.4
AI836003
expressed sequence AI836003
chr3_+_95164306 0.213 ENSMUST00000107217.1
ENSMUST00000168321.1
Sema6c

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C

chr19_-_4334001 0.213 ENSMUST00000176653.1
Kdm2a
lysine (K)-specific demethylase 2A
chr10_-_70655934 0.210 ENSMUST00000162144.1
ENSMUST00000162793.1
Phyhipl

phytanoyl-CoA hydroxylase interacting protein-like

chr10_+_80261457 0.208 ENSMUST00000156935.1
Dazap1
DAZ associated protein 1
chr5_-_124187150 0.208 ENSMUST00000161938.1
Pitpnm2
phosphatidylinositol transfer protein, membrane-associated 2
chr13_-_67399738 0.196 ENSMUST00000181071.1
ENSMUST00000109732.1
Zfp429

zinc finger protein 429

chr4_-_110292719 0.190 ENSMUST00000106601.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr14_-_79481268 0.186 ENSMUST00000022601.5
Wbp4
WW domain binding protein 4
chr10_+_61175206 0.171 ENSMUST00000079235.5
Tbata
thymus, brain and testes associated
chr8_-_105933832 0.170 ENSMUST00000034368.6
Ctrl
chymotrypsin-like
chr11_-_69413675 0.163 ENSMUST00000094077.4
Kdm6b
KDM1 lysine (K)-specific demethylase 6B
chr14_-_16249675 0.158 ENSMUST00000022311.4
Oxsm
3-oxoacyl-ACP synthase, mitochondrial
chr11_-_95514570 0.154 ENSMUST00000058866.7
Nxph3
neurexophilin 3
chr9_-_71896047 0.151 ENSMUST00000184448.1
Tcf12
transcription factor 12
chr13_-_67375729 0.151 ENSMUST00000172266.1
ENSMUST00000057070.8
Zfp456

zinc finger protein 456

chr10_+_127759780 0.148 ENSMUST00000128247.1
RP23-386P10.11
Protein Rdh9
chrX_+_166344692 0.141 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
Gpm6b





glycoprotein m6b





chr11_-_68853119 0.138 ENSMUST00000018880.7
Ndel1
nuclear distribution gene E-like homolog 1 (A. nidulans)
chr10_-_22149270 0.113 ENSMUST00000179054.1
ENSMUST00000069372.6
E030030I06Rik

RIKEN cDNA E030030I06 gene

chr2_-_80128834 0.105 ENSMUST00000102654.4
ENSMUST00000102655.3
Pde1a

phosphodiesterase 1A, calmodulin-dependent

chr9_-_60649793 0.104 ENSMUST00000053171.7
Lrrc49
leucine rich repeat containing 49
chr6_-_148831395 0.104 ENSMUST00000145960.1
Ipo8
importin 8
chr2_+_150323702 0.102 ENSMUST00000133235.2
Gm10130
predicted gene 10130
chr5_-_144223516 0.097 ENSMUST00000085701.6
Tecpr1
tectonin beta-propeller repeat containing 1
chr2_+_72054598 0.097 ENSMUST00000028525.5
Rapgef4
Rap guanine nucleotide exchange factor (GEF) 4
chr11_-_103938211 0.088 ENSMUST00000133774.2
ENSMUST00000149642.1
Nsf

N-ethylmaleimide sensitive fusion protein

chr10_-_14718191 0.088 ENSMUST00000020016.4
Gje1
gap junction protein, epsilon 1
chr3_+_95434386 0.087 ENSMUST00000102749.4
ENSMUST00000090804.5
ENSMUST00000107161.1
ENSMUST00000107160.1
ENSMUST00000015666.10
Arnt




aryl hydrocarbon receptor nuclear translocator




chr3_+_58525821 0.087 ENSMUST00000029387.8
Eif2a
eukaryotic translation initiation factor 2A
chr16_-_31314804 0.073 ENSMUST00000115230.1
ENSMUST00000130560.1
Apod

apolipoprotein D

chr5_-_33782810 0.073 ENSMUST00000005431.5
Letm1
leucine zipper-EF-hand containing transmembrane protein 1
chr10_+_36974536 0.065 ENSMUST00000019911.7
Hdac2
histone deacetylase 2
chr6_-_28421680 0.065 ENSMUST00000090511.3
Gcc1
golgi coiled coil 1
chr14_-_61556881 0.064 ENSMUST00000022497.8
Spryd7
SPRY domain containing 7
chr13_-_97747373 0.063 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr6_-_122340525 0.060 ENSMUST00000112600.2
Phc1
polyhomeotic-like 1 (Drosophila)
chr10_+_127849917 0.058 ENSMUST00000077530.2
Rdh19
retinol dehydrogenase 19
chrX_-_150814265 0.051 ENSMUST00000026302.6
ENSMUST00000129768.1
ENSMUST00000112699.2
Maged2


melanoma antigen, family D, 2


chr11_-_97996171 0.046 ENSMUST00000042971.9
Arl5c
ADP-ribosylation factor-like 5C
chr1_+_37997975 0.037 ENSMUST00000027252.7
Eif5b
eukaryotic translation initiation factor 5B
chr4_+_150853919 0.034 ENSMUST00000073600.2
Errfi1
ERBB receptor feedback inhibitor 1
chr2_+_91710900 0.034 ENSMUST00000142692.1
ENSMUST00000090608.5
Harbi1

harbinger transposase derived 1

chr4_+_80910646 0.030 ENSMUST00000055922.3
Lurap1l
leucine rich adaptor protein 1-like
chr1_+_110099295 0.026 ENSMUST00000134301.1
Cdh7
cadherin 7, type 2
chrX_+_164373363 0.018 ENSMUST00000033751.7
Figf
c-fos induced growth factor
chr8_-_122476036 0.017 ENSMUST00000014614.3
Rnf166
ring finger protein 166
chr7_+_82867327 0.013 ENSMUST00000082237.5
Mex3b
mex3 homolog B (C. elegans)
chr14_-_51988829 0.013 ENSMUST00000181008.1
Gm16617
predicted gene, 16617
chr5_-_122989260 0.008 ENSMUST00000118027.1
Kdm2b
lysine (K)-specific demethylase 2B
chr8_+_94838321 0.004 ENSMUST00000034234.8
ENSMUST00000159871.1
Coq9

coenzyme Q9 homolog (yeast)

chr1_+_6730051 0.001 ENSMUST00000043578.6
ENSMUST00000131467.1
ENSMUST00000150761.1
ENSMUST00000151281.1
St18



suppression of tumorigenicity 18




Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.3 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.5 1.4 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.4 1.3 GO:0032240 RNA import into nucleus(GO:0006404) mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.4 2.1 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.4 1.6 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.4 2.3 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.3 1.4 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.2 0.6 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923)
0.2 0.6 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.2 0.5 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.2 1.4 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 3.6 GO:0021860 pyramidal neuron development(GO:0021860)
0.1 1.3 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1 1.0 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 1.6 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.1 0.9 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1 1.7 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 0.6 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1 3.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 1.3 GO:0070914 nucleosome disassembly(GO:0006337) UV-damage excision repair(GO:0070914)
0.1 3.3 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1 0.3 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.1 0.5 GO:0061368 maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.1 0.3 GO:0042701 progesterone secretion(GO:0042701)
0.1 0.3 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.5 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.5 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.7 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.4 GO:0060510 Type II pneumocyte differentiation(GO:0060510)
0.0 3.3 GO:0021766 hippocampus development(GO:0021766)
0.0 0.4 GO:0030397 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.0 0.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.2 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.0 0.2 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.0 0.5 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.8 GO:0001523 retinoid metabolic process(GO:0001523)
0.0 0.1 GO:2000097 negative regulation of monocyte chemotactic protein-1 production(GO:0071638) regulation of smooth muscle cell-matrix adhesion(GO:2000097) negative regulation of lymphocyte migration(GO:2000402)
0.0 0.1 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.0 0.3 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.0 0.5 GO:0021702 cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.3 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.6 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 1.6 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 3.3 GO:0050821 protein stabilization(GO:0050821)
0.0 0.1 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
0.0 0.8 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.7 GO:0051438 regulation of ubiquitin-protein transferase activity(GO:0051438)
0.0 0.5 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 1.1 GO:0046889 positive regulation of lipid biosynthetic process(GO:0046889)
0.0 0.0 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0 0.2 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.1 GO:0034214 protein hexamerization(GO:0034214)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.6 GO:0097441 basilar dendrite(GO:0097441)
0.2 1.3 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.2 0.9 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 2.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 2.9 GO:0031430 M band(GO:0031430)
0.1 0.8 GO:0001739 sex chromatin(GO:0001739)
0.1 1.4 GO:0042588 zymogen granule(GO:0042588)
0.1 0.6 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 1.4 GO:0071564 npBAF complex(GO:0071564)
0.1 3.2 GO:0045171 intercellular bridge(GO:0045171)
0.1 0.7 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 0.6 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.4 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.6 GO:0032433 filopodium tip(GO:0032433)
0.0 1.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 2.3 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 1.2 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.5 GO:0097038 phosphatidylinositol 3-kinase complex(GO:0005942) perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0044316 cone cell pedicle(GO:0044316)
0.0 1.1 GO:0005811 lipid particle(GO:0005811)
0.0 0.7 GO:0031201 SNARE complex(GO:0031201)
0.0 0.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.5 GO:0016592 mediator complex(GO:0016592)
0.0 1.2 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.8 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 2.4 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 3.4 GO:0042605 peptide antigen binding(GO:0042605)
0.1 1.7 GO:0031005 filamin binding(GO:0031005)
0.1 2.1 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 0.5 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.5 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.1 2.3 GO:0016208 AMP binding(GO:0016208)
0.1 0.4 GO:0070012 oligopeptidase activity(GO:0070012)
0.1 1.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.9 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 3.8 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.6 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.8 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 1.4 GO:0031489 myosin V binding(GO:0031489)
0.1 0.7 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 2.3 GO:0070888 E-box binding(GO:0070888)
0.1 0.3 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 1.3 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.2 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.0 0.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.3 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 0.6 GO:0030275 LRR domain binding(GO:0030275)
0.0 1.4 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 1.3 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0035851 histone deacetylase activity (H4-K16 specific)(GO:0034739) Krueppel-associated box domain binding(GO:0035851)
0.0 3.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.4 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.2 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 0.5 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 0.3 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.0 1.4 PID_E2F_PATHWAY E2F transcription factor network
0.0 0.5 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.0 0.7 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.0 0.6 PID_FGF_PATHWAY FGF signaling pathway
0.0 0.6 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 0.4 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 2.0 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.6 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.3 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 1.7 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.5 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.6 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.6 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.6 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.0 0.3 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.6 REACTOME_INTERFERON_GAMMA_SIGNALING Genes involved in Interferon gamma signaling
0.0 0.3 REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1