Motif ID: Obox3

Z-value: 0.350


Transcription factors associated with Obox3:

Gene SymbolEntrez IDGene Name
Obox3 ENSMUSG00000066772.6 Obox3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Obox3mm10_v2_chr7_-_15627876_156278760.076.7e-01Click!


Activity profile for motif Obox3.

activity profile for motif Obox3


Sorted Z-values histogram for motif Obox3

Sorted Z-values for motif Obox3



Network of associatons between targets according to the STRING database.



First level regulatory network of Obox3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_-_43393346 1.620 ENSMUST00000025379.7
Dpysl3
dihydropyrimidinase-like 3
chr6_+_4902913 1.180 ENSMUST00000175889.1
ENSMUST00000168998.2
Ppp1r9a

protein phosphatase 1, regulatory (inhibitor) subunit 9A

chr6_-_91807318 1.131 ENSMUST00000159684.1
Grip2
glutamate receptor interacting protein 2
chr7_-_103843154 1.112 ENSMUST00000063957.4
Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr4_+_74013442 1.110 ENSMUST00000098006.2
ENSMUST00000084474.5
Frmd3

FERM domain containing 3

chr6_-_91807424 1.045 ENSMUST00000162300.1
Grip2
glutamate receptor interacting protein 2
chr14_-_19977249 1.000 ENSMUST00000160013.1
Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr11_+_70459940 0.977 ENSMUST00000147289.1
ENSMUST00000126105.1
Zmynd15

zinc finger, MYND-type containing 15

chr14_+_61138445 0.970 ENSMUST00000089394.3
ENSMUST00000119509.1
Sacs

sacsin

chr14_-_19977040 0.861 ENSMUST00000159028.1
Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr1_+_118389058 0.856 ENSMUST00000049404.6
ENSMUST00000070989.7
ENSMUST00000165223.1
ENSMUST00000178710.1
Clasp1



CLIP associating protein 1



chr14_-_19977151 0.829 ENSMUST00000055100.7
ENSMUST00000162425.1
Gng2

guanine nucleotide binding protein (G protein), gamma 2

chr1_-_119836999 0.795 ENSMUST00000163621.1
ENSMUST00000168303.1
Ptpn4

protein tyrosine phosphatase, non-receptor type 4

chr2_+_136892168 0.723 ENSMUST00000099311.2
Slx4ip
SLX4 interacting protein
chr1_+_178187721 0.704 ENSMUST00000159284.1
Desi2
desumoylating isopeptidase 2
chr19_+_3768112 0.698 ENSMUST00000005518.9
ENSMUST00000113967.1
ENSMUST00000152935.1
ENSMUST00000176262.1
ENSMUST00000176407.1
ENSMUST00000176926.1
ENSMUST00000176512.1
Suv420h1






suppressor of variegation 4-20 homolog 1 (Drosophila)






chr11_-_70459957 0.634 ENSMUST00000019064.2
Cxcl16
chemokine (C-X-C motif) ligand 16
chr1_-_52232296 0.627 ENSMUST00000114512.1
Gls
glutaminase
chr14_-_69805524 0.576 ENSMUST00000022665.2
Rhobtb2
Rho-related BTB domain containing 2
chr7_+_35802593 0.569 ENSMUST00000052454.2
E130304I02Rik
RIKEN cDNA E130304I02 gene
chr12_+_81631369 0.567 ENSMUST00000036116.5
Ttc9
tetratricopeptide repeat domain 9
chr4_+_74242468 0.547 ENSMUST00000077851.3
Kdm4c
lysine (K)-specific demethylase 4C
chr19_+_3767397 0.535 ENSMUST00000113974.4
ENSMUST00000113972.2
ENSMUST00000113973.1
ENSMUST00000113977.2
ENSMUST00000052699.6
ENSMUST00000113968.2
Suv420h1





suppressor of variegation 4-20 homolog 1 (Drosophila)





chr6_-_122340200 0.526 ENSMUST00000159384.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr19_+_44992127 0.497 ENSMUST00000179305.1
Sema4g
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr9_-_50617228 0.487 ENSMUST00000147671.1
ENSMUST00000145139.1
ENSMUST00000155435.1
AU019823


expressed sequence AU019823


chr18_+_37496997 0.458 ENSMUST00000059571.5
Pcdhb19
protocadherin beta 19
chr4_+_115000174 0.428 ENSMUST00000129957.1
Stil
Scl/Tal1 interrupting locus
chr13_-_23369156 0.391 ENSMUST00000125328.1
ENSMUST00000145451.1
ENSMUST00000050101.2
Zfp322a


zinc finger protein 322A


chrX_+_74424632 0.329 ENSMUST00000114129.2
ENSMUST00000132749.1
Ikbkg

inhibitor of kappaB kinase gamma

chr4_+_62663620 0.314 ENSMUST00000126338.1
Rgs3
regulator of G-protein signaling 3
chrX_+_134295225 0.313 ENSMUST00000037687.7
Tmem35
transmembrane protein 35
chr11_+_109649376 0.305 ENSMUST00000106677.1
Prkar1a
protein kinase, cAMP dependent regulatory, type I, alpha
chr19_+_3767953 0.298 ENSMUST00000113970.1
Suv420h1
suppressor of variegation 4-20 homolog 1 (Drosophila)
chr9_+_109051090 0.286 ENSMUST00000059097.8
Shisa5
shisa homolog 5 (Xenopus laevis)
chrX_+_74424534 0.270 ENSMUST00000135165.1
ENSMUST00000114128.1
ENSMUST00000114133.2
ENSMUST00000004330.3
Ikbkg



inhibitor of kappaB kinase gamma



chr1_+_140246216 0.253 ENSMUST00000119786.1
ENSMUST00000120796.1
ENSMUST00000060201.8
ENSMUST00000120709.1
Kcnt2



potassium channel, subfamily T, member 2



chr18_-_60848911 0.247 ENSMUST00000177172.1
ENSMUST00000175934.1
ENSMUST00000176630.1
Tcof1


Treacher Collins Franceschetti syndrome 1, homolog


chrX_+_52791179 0.240 ENSMUST00000101588.1
Ccdc160
coiled-coil domain containing 160
chr1_-_133701881 0.236 ENSMUST00000167348.1
Gm17678
predicted gene, 17678
chr1_+_178187417 0.181 ENSMUST00000161075.1
ENSMUST00000027783.7
Desi2

desumoylating isopeptidase 2

chr9_+_57825918 0.155 ENSMUST00000165858.1
Gm17231
predicted gene 17231
chr9_+_108460518 0.097 ENSMUST00000061209.5
Ccdc71
coiled-coil domain containing 71
chr4_+_115000156 0.083 ENSMUST00000030490.6
Stil
Scl/Tal1 interrupting locus
chr10_+_111972664 0.078 ENSMUST00000163048.1
ENSMUST00000174653.1
Krr1

KRR1, small subunit (SSU) processome component, homolog (yeast)

chr3_-_63964768 0.074 ENSMUST00000029402.8
Slc33a1
solute carrier family 33 (acetyl-CoA transporter), member 1
chr9_-_21312255 0.056 ENSMUST00000115433.3
ENSMUST00000003397.7
Ap1m2

adaptor protein complex AP-1, mu 2 subunit

chr18_+_42511496 0.055 ENSMUST00000025375.7
Tcerg1
transcription elongation regulator 1 (CA150)
chr7_-_44986313 0.042 ENSMUST00000045325.6
ENSMUST00000085387.4
ENSMUST00000107840.1
ENSMUST00000107843.3
ENSMUST00000107842.3
Prmt1




protein arginine N-methyltransferase 1




chr18_-_3281712 0.034 ENSMUST00000182204.1
ENSMUST00000154705.1
ENSMUST00000182833.1
ENSMUST00000151084.1
Crem



cAMP responsive element modulator



chr7_-_25398697 0.033 ENSMUST00000105177.2
ENSMUST00000149349.1
Lipe

lipase, hormone sensitive

chrX_+_142227923 0.023 ENSMUST00000042329.5
Nxt2
nuclear transport factor 2-like export factor 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.2 1.1 GO:0015671 oxygen transport(GO:0015671)
0.2 2.2 GO:0014824 artery smooth muscle contraction(GO:0014824)
0.1 0.6 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 0.9 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 1.6 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.5 GO:0033504 floor plate development(GO:0033504)
0.0 0.5 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.6 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.6 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.3 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.2 GO:0014029 neural crest formation(GO:0014029)
0.0 0.0 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.0 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.5 GO:0050919 negative chemotaxis(GO:0050919)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:1990761 growth cone lamellipodium(GO:1990761)
0.2 0.9 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 1.1 GO:0005833 hemoglobin complex(GO:0005833)
0.1 2.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.5 GO:0001739 sex chromatin(GO:0001739)
0.0 0.6 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 1.6 GO:0031941 filamentous actin(GO:0031941)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 2.2 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.5 GO:0005721 pericentric heterochromatin(GO:0005721)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.2 0.6 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.2 1.6 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 0.9 GO:0043515 kinetochore binding(GO:0043515)
0.1 2.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.6 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.8 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 0.6 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 1.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454) histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 1.0 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 2.2 GO:0035254 glutamate receptor binding(GO:0035254)
0.0 0.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.0 GO:0030519 snoRNP binding(GO:0030519)
0.0 1.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.7 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 0.6 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.5 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.5 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 2.7 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 1.6 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 0.6 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.6 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.6 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.9 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB