Motif ID: Tfeb_Usf1_Srebf1_Usf2_Bhlhe41_Srebf2
Z-value: 1.252






Transcription factors associated with Tfeb_Usf1_Srebf1_Usf2_Bhlhe41_Srebf2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Bhlhe41 | ENSMUSG00000030256.5 | Bhlhe41 |
Srebf1 | ENSMUSG00000020538.9 | Srebf1 |
Srebf2 | ENSMUSG00000022463.7 | Srebf2 |
Tfeb | ENSMUSG00000023990.12 | Tfeb |
Usf1 | ENSMUSG00000026641.7 | Usf1 |
Usf2 | ENSMUSG00000058239.7 | Usf2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Usf2 | mm10_v2_chr7_-_30956742_30956803 | -0.51 | 6.5e-04 | Click! |
Srebf2 | mm10_v2_chr15_+_82147238_82147275 | 0.32 | 4.1e-02 | Click! |
Usf1 | mm10_v2_chr1_+_171411343_171411384 | -0.26 | 1.0e-01 | Click! |
Srebf1 | mm10_v2_chr11_-_60210410_60210465 | 0.18 | 2.7e-01 | Click! |
Tfeb | mm10_v2_chr17_+_47737030_47737107 | -0.12 | 4.7e-01 | Click! |
First level regulatory network of Tfeb_Usf1_Srebf1_Usf2_Bhlhe41_Srebf2
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Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
4.8 | 19.3 | GO:0070829 | heterochromatin maintenance(GO:0070829) |
4.0 | 11.9 | GO:0032915 | positive regulation of transforming growth factor beta2 production(GO:0032915) |
3.4 | 10.3 | GO:1904959 | elastin biosynthetic process(GO:0051542) copper ion export(GO:0060003) regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959) |
2.6 | 7.9 | GO:0099547 | regulation of translation at synapse, modulating synaptic transmission(GO:0099547) regulation of translation at postsynapse, modulating synaptic transmission(GO:0099578) positive regulation of intracellular transport of viral material(GO:1901254) |
2.6 | 7.8 | GO:0090204 | protein localization to nuclear pore(GO:0090204) |
2.3 | 9.2 | GO:0016340 | calcium-dependent cell-matrix adhesion(GO:0016340) |
2.2 | 6.5 | GO:0043379 | memory T cell differentiation(GO:0043379) |
2.1 | 10.5 | GO:1902683 | regulation of receptor localization to synapse(GO:1902683) |
2.1 | 8.4 | GO:0072531 | pyrimidine-containing compound transmembrane transport(GO:0072531) |
2.1 | 8.3 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
1.6 | 4.9 | GO:0060399 | positive regulation of growth hormone receptor signaling pathway(GO:0060399) |
1.6 | 6.5 | GO:0090126 | protein complex assembly involved in synapse maturation(GO:0090126) |
1.6 | 4.8 | GO:0010845 | positive regulation of reciprocal meiotic recombination(GO:0010845) |
1.4 | 9.9 | GO:0045346 | regulation of MHC class II biosynthetic process(GO:0045346) |
1.4 | 5.6 | GO:2000211 | regulation of glutamate metabolic process(GO:2000211) |
1.4 | 6.9 | GO:1900170 | negative regulation of glucocorticoid mediated signaling pathway(GO:1900170) |
1.4 | 4.1 | GO:0019482 | beta-alanine metabolic process(GO:0019482) |
1.2 | 4.9 | GO:2001245 | regulation of phosphatidylcholine biosynthetic process(GO:2001245) |
1.2 | 3.6 | GO:2000312 | regulation of kainate selective glutamate receptor activity(GO:2000312) |
1.2 | 5.8 | GO:0042117 | monocyte activation(GO:0042117) |
1.1 | 4.6 | GO:0060729 | intestinal epithelial structure maintenance(GO:0060729) |
1.1 | 5.7 | GO:1904684 | negative regulation of metalloendopeptidase activity(GO:1904684) |
1.1 | 4.5 | GO:0071638 | negative regulation of monocyte chemotactic protein-1 production(GO:0071638) |
1.1 | 6.7 | GO:0051013 | microtubule severing(GO:0051013) |
1.1 | 3.2 | GO:0070428 | granuloma formation(GO:0002432) negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070432) |
1.0 | 7.3 | GO:0034058 | endosomal vesicle fusion(GO:0034058) |
1.0 | 4.1 | GO:0007066 | female meiosis sister chromatid cohesion(GO:0007066) |
1.0 | 3.1 | GO:1904760 | myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760) |
0.9 | 4.6 | GO:0034162 | toll-like receptor 9 signaling pathway(GO:0034162) |
0.9 | 6.4 | GO:0035826 | rubidium ion transport(GO:0035826) |
0.9 | 2.7 | GO:0001978 | regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) |
0.9 | 5.4 | GO:2000672 | negative regulation of motor neuron apoptotic process(GO:2000672) |
0.9 | 0.9 | GO:0016240 | autophagosome docking(GO:0016240) |
0.9 | 2.6 | GO:0043181 | vacuolar sequestering(GO:0043181) |
0.9 | 3.4 | GO:0097118 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) |
0.8 | 4.1 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
0.8 | 4.1 | GO:1990034 | calcium ion export from cell(GO:1990034) |
0.8 | 25.9 | GO:0097352 | autophagosome maturation(GO:0097352) |
0.8 | 2.4 | GO:1900369 | negative regulation of RNA interference(GO:1900369) |
0.8 | 8.6 | GO:0033148 | positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148) |
0.7 | 5.8 | GO:2000973 | regulation of pro-B cell differentiation(GO:2000973) |
0.7 | 19.5 | GO:0015991 | ATP hydrolysis coupled proton transport(GO:0015991) |
0.7 | 4.9 | GO:0070494 | regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) |
0.7 | 3.4 | GO:1903012 | positive regulation of bone development(GO:1903012) |
0.7 | 1.3 | GO:0008626 | granzyme-mediated apoptotic signaling pathway(GO:0008626) |
0.6 | 1.3 | GO:0035469 | determination of pancreatic left/right asymmetry(GO:0035469) determination of liver left/right asymmetry(GO:0071910) |
0.6 | 4.4 | GO:0030242 | pexophagy(GO:0030242) |
0.6 | 2.5 | GO:0007352 | zygotic specification of dorsal/ventral axis(GO:0007352) positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224) |
0.6 | 2.5 | GO:0060830 | ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) myotome development(GO:0061055) |
0.6 | 1.8 | GO:0003349 | epicardium-derived cardiac endothelial cell differentiation(GO:0003349) |
0.6 | 19.6 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
0.6 | 1.8 | GO:2000016 | negative regulation of determination of dorsal identity(GO:2000016) |
0.6 | 5.9 | GO:1901409 | positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
0.6 | 2.3 | GO:0097494 | regulation of vesicle size(GO:0097494) |
0.6 | 1.1 | GO:0060743 | epithelial cell maturation involved in prostate gland development(GO:0060743) |
0.5 | 1.1 | GO:1903774 | positive regulation of viral budding via host ESCRT complex(GO:1903774) |
0.5 | 0.5 | GO:0030576 | Cajal body organization(GO:0030576) |
0.5 | 1.6 | GO:0090238 | positive regulation of arachidonic acid secretion(GO:0090238) |
0.5 | 1.6 | GO:0006868 | glutamine transport(GO:0006868) |
0.5 | 1.6 | GO:0043686 | co-translational protein modification(GO:0043686) |
0.5 | 3.5 | GO:0030718 | germ-line stem cell population maintenance(GO:0030718) |
0.5 | 1.5 | GO:0090526 | regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526) |
0.5 | 4.0 | GO:1903207 | neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208) |
0.5 | 5.5 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
0.5 | 0.5 | GO:0052151 | positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139) |
0.5 | 3.5 | GO:0015808 | L-alanine transport(GO:0015808) |
0.5 | 0.5 | GO:0006818 | hydrogen transport(GO:0006818) |
0.5 | 22.1 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
0.5 | 1.5 | GO:0035694 | mitochondrial protein catabolic process(GO:0035694) |
0.5 | 3.8 | GO:0015074 | DNA integration(GO:0015074) |
0.5 | 2.8 | GO:0042256 | mature ribosome assembly(GO:0042256) |
0.5 | 1.4 | GO:0035356 | cellular triglyceride homeostasis(GO:0035356) |
0.4 | 4.9 | GO:0035520 | monoubiquitinated protein deubiquitination(GO:0035520) |
0.4 | 8.4 | GO:0002115 | store-operated calcium entry(GO:0002115) |
0.4 | 3.9 | GO:0070816 | phosphorylation of RNA polymerase II C-terminal domain(GO:0070816) |
0.4 | 6.0 | GO:0071378 | growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378) |
0.4 | 2.6 | GO:0010730 | negative regulation of hydrogen peroxide metabolic process(GO:0010727) negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) |
0.4 | 4.2 | GO:1900113 | negative regulation of histone H3-K9 trimethylation(GO:1900113) |
0.4 | 2.9 | GO:1903441 | protein localization to ciliary membrane(GO:1903441) |
0.4 | 1.7 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
0.4 | 4.5 | GO:0045974 | miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974) |
0.4 | 2.8 | GO:0000414 | regulation of histone H3-K36 methylation(GO:0000414) |
0.4 | 2.4 | GO:0061502 | early endosome to recycling endosome transport(GO:0061502) |
0.4 | 1.2 | GO:0032241 | positive regulation of nucleobase-containing compound transport(GO:0032241) |
0.4 | 1.2 | GO:1903061 | regulation of protein lipidation(GO:1903059) positive regulation of protein lipidation(GO:1903061) |
0.4 | 2.3 | GO:0071442 | positive regulation of histone H3-K14 acetylation(GO:0071442) |
0.4 | 1.9 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
0.4 | 3.4 | GO:0051901 | positive regulation of mitochondrial depolarization(GO:0051901) |
0.4 | 2.3 | GO:0035188 | blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684) |
0.4 | 3.8 | GO:1903301 | positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301) |
0.4 | 0.7 | GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
0.4 | 0.7 | GO:0006681 | galactosylceramide metabolic process(GO:0006681) galactolipid metabolic process(GO:0019374) |
0.4 | 1.8 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
0.4 | 1.8 | GO:0000019 | regulation of mitotic recombination(GO:0000019) |
0.4 | 1.8 | GO:0042364 | water-soluble vitamin biosynthetic process(GO:0042364) |
0.4 | 4.3 | GO:0007141 | male meiosis I(GO:0007141) |
0.3 | 1.4 | GO:0045113 | regulation of integrin biosynthetic process(GO:0045113) |
0.3 | 9.4 | GO:0031571 | mitotic G1 DNA damage checkpoint(GO:0031571) |
0.3 | 3.1 | GO:0006104 | succinyl-CoA metabolic process(GO:0006104) |
0.3 | 1.4 | GO:0006344 | maintenance of chromatin silencing(GO:0006344) |
0.3 | 2.4 | GO:0035434 | copper ion transmembrane transport(GO:0035434) |
0.3 | 2.4 | GO:1903551 | regulation of extracellular exosome assembly(GO:1903551) |
0.3 | 1.7 | GO:0006689 | ganglioside catabolic process(GO:0006689) |
0.3 | 1.0 | GO:0097151 | positive regulation of inhibitory postsynaptic potential(GO:0097151) |
0.3 | 3.3 | GO:0070131 | positive regulation of mitochondrial translation(GO:0070131) |
0.3 | 4.0 | GO:0010807 | regulation of synaptic vesicle priming(GO:0010807) |
0.3 | 1.3 | GO:0021586 | pons maturation(GO:0021586) |
0.3 | 2.3 | GO:0090148 | membrane fission(GO:0090148) |
0.3 | 2.3 | GO:1990416 | cellular response to brain-derived neurotrophic factor stimulus(GO:1990416) |
0.3 | 1.9 | GO:0009405 | pathogenesis(GO:0009405) |
0.3 | 3.8 | GO:0043982 | histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982) |
0.3 | 0.6 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
0.3 | 2.2 | GO:0016185 | synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) |
0.3 | 5.3 | GO:0045898 | regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) |
0.3 | 3.7 | GO:0060693 | regulation of branching involved in salivary gland morphogenesis(GO:0060693) |
0.3 | 2.8 | GO:1900244 | positive regulation of synaptic vesicle endocytosis(GO:1900244) |
0.3 | 0.6 | GO:0070625 | zymogen granule exocytosis(GO:0070625) |
0.3 | 3.4 | GO:0048570 | notochord morphogenesis(GO:0048570) |
0.3 | 0.9 | GO:0035963 | response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963) |
0.3 | 0.9 | GO:0060971 | embryonic heart tube left/right pattern formation(GO:0060971) |
0.3 | 0.9 | GO:0070779 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
0.3 | 2.1 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
0.3 | 2.3 | GO:0044791 | modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) |
0.3 | 0.9 | GO:0035405 | histone-threonine phosphorylation(GO:0035405) |
0.3 | 1.1 | GO:0060083 | smooth muscle contraction involved in micturition(GO:0060083) |
0.3 | 1.1 | GO:1904694 | negative regulation of vascular smooth muscle contraction(GO:1904694) |
0.3 | 0.8 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
0.3 | 11.4 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
0.3 | 0.8 | GO:0045359 | positive regulation of interferon-beta biosynthetic process(GO:0045359) |
0.3 | 0.8 | GO:0006011 | UDP-glucose metabolic process(GO:0006011) |
0.3 | 1.9 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) negative regulation of actin nucleation(GO:0051126) |
0.3 | 0.5 | GO:1903181 | late endosome to lysosome transport(GO:1902774) regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) |
0.3 | 3.5 | GO:0043084 | penile erection(GO:0043084) |
0.3 | 42.2 | GO:0008643 | carbohydrate transport(GO:0008643) |
0.3 | 3.9 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
0.3 | 1.3 | GO:0030205 | dermatan sulfate metabolic process(GO:0030205) |
0.3 | 17.3 | GO:0070936 | protein K48-linked ubiquitination(GO:0070936) |
0.2 | 4.0 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
0.2 | 0.2 | GO:1900377 | negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377) |
0.2 | 1.0 | GO:0045213 | neurotransmitter receptor metabolic process(GO:0045213) |
0.2 | 3.4 | GO:0039703 | viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) |
0.2 | 0.7 | GO:0060155 | platelet dense granule organization(GO:0060155) |
0.2 | 1.9 | GO:2000766 | negative regulation of cytoplasmic translation(GO:2000766) |
0.2 | 1.7 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
0.2 | 0.7 | GO:0038180 | nerve growth factor signaling pathway(GO:0038180) |
0.2 | 1.6 | GO:2000323 | negative regulation of glucocorticoid receptor signaling pathway(GO:2000323) |
0.2 | 8.2 | GO:0045214 | sarcomere organization(GO:0045214) |
0.2 | 0.5 | GO:0034144 | negative regulation of toll-like receptor 4 signaling pathway(GO:0034144) |
0.2 | 17.7 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
0.2 | 0.7 | GO:1901017 | negative regulation of potassium ion transmembrane transporter activity(GO:1901017) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817) |
0.2 | 2.7 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
0.2 | 0.9 | GO:0035426 | extracellular matrix-cell signaling(GO:0035426) |
0.2 | 0.9 | GO:0019276 | UDP-N-acetylgalactosamine metabolic process(GO:0019276) |
0.2 | 2.7 | GO:0070842 | aggresome assembly(GO:0070842) |
0.2 | 1.1 | GO:1905150 | regulation of voltage-gated sodium channel activity(GO:1905150) |
0.2 | 3.3 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
0.2 | 3.3 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
0.2 | 0.4 | GO:0051771 | negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) |
0.2 | 2.2 | GO:0061470 | T follicular helper cell differentiation(GO:0061470) |
0.2 | 0.9 | GO:0006668 | sphinganine-1-phosphate metabolic process(GO:0006668) |
0.2 | 10.7 | GO:0036465 | synaptic vesicle recycling(GO:0036465) |
0.2 | 2.4 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
0.2 | 2.6 | GO:0035020 | regulation of Rac protein signal transduction(GO:0035020) |
0.2 | 1.0 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
0.2 | 1.6 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
0.2 | 6.6 | GO:0008333 | endosome to lysosome transport(GO:0008333) |
0.2 | 1.4 | GO:0031340 | positive regulation of vesicle fusion(GO:0031340) |
0.2 | 0.4 | GO:0033634 | positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) |
0.2 | 0.8 | GO:0002188 | translation reinitiation(GO:0002188) |
0.2 | 0.8 | GO:0001956 | positive regulation of neurotransmitter secretion(GO:0001956) |
0.2 | 1.1 | GO:0015015 | heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015) |
0.2 | 0.2 | GO:1902256 | apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256) |
0.2 | 2.8 | GO:0051481 | negative regulation of cytosolic calcium ion concentration(GO:0051481) |
0.2 | 0.6 | GO:1901052 | sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053) |
0.2 | 4.4 | GO:0045071 | negative regulation of viral genome replication(GO:0045071) |
0.2 | 0.9 | GO:0048102 | autophagic cell death(GO:0048102) |
0.2 | 0.7 | GO:0046487 | glyoxylate metabolic process(GO:0046487) |
0.2 | 7.0 | GO:0036075 | endochondral ossification(GO:0001958) replacement ossification(GO:0036075) |
0.2 | 0.7 | GO:0006710 | androgen catabolic process(GO:0006710) |
0.2 | 0.9 | GO:0070574 | cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574) |
0.2 | 0.5 | GO:1900126 | negative regulation of hyaluronan biosynthetic process(GO:1900126) |
0.2 | 1.7 | GO:0019243 | methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727) |
0.2 | 1.2 | GO:2000786 | positive regulation of autophagosome assembly(GO:2000786) |
0.2 | 2.6 | GO:0051703 | social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703) |
0.2 | 1.5 | GO:0006620 | posttranslational protein targeting to membrane(GO:0006620) |
0.2 | 1.3 | GO:0018095 | protein polyglutamylation(GO:0018095) |
0.2 | 0.9 | GO:0006308 | DNA catabolic process(GO:0006308) |
0.2 | 2.2 | GO:0006613 | cotranslational protein targeting to membrane(GO:0006613) |
0.2 | 10.5 | GO:0030433 | ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) |
0.2 | 1.1 | GO:0072015 | purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264) glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310) |
0.2 | 1.7 | GO:0032688 | negative regulation of interferon-beta production(GO:0032688) |
0.2 | 0.6 | GO:0089711 | L-glutamate transmembrane transport(GO:0089711) |
0.2 | 1.8 | GO:0030828 | positive regulation of cGMP biosynthetic process(GO:0030828) |
0.2 | 1.5 | GO:0071625 | vocalization behavior(GO:0071625) |
0.2 | 1.5 | GO:0033623 | regulation of integrin activation(GO:0033623) |
0.1 | 0.6 | GO:0035093 | spermatogenesis, exchange of chromosomal proteins(GO:0035093) |
0.1 | 1.2 | GO:0044387 | negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387) |
0.1 | 3.5 | GO:0014002 | astrocyte development(GO:0014002) |
0.1 | 2.4 | GO:0006465 | signal peptide processing(GO:0006465) |
0.1 | 0.9 | GO:0048069 | eye pigmentation(GO:0048069) |
0.1 | 0.7 | GO:0000480 | endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480) |
0.1 | 0.3 | GO:0070309 | lens fiber cell morphogenesis(GO:0070309) |
0.1 | 1.3 | GO:0006833 | water transport(GO:0006833) |
0.1 | 1.8 | GO:0016926 | protein desumoylation(GO:0016926) |
0.1 | 0.4 | GO:0060290 | noradrenergic neuron differentiation(GO:0003357) transdifferentiation(GO:0060290) |
0.1 | 1.5 | GO:1990403 | embryonic brain development(GO:1990403) |
0.1 | 0.7 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
0.1 | 3.6 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
0.1 | 1.1 | GO:1901844 | regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) |
0.1 | 0.5 | GO:0009212 | dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075) |
0.1 | 0.5 | GO:2000110 | protein sialylation(GO:1990743) negative regulation of macrophage apoptotic process(GO:2000110) |
0.1 | 3.3 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
0.1 | 0.6 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
0.1 | 0.2 | GO:0043987 | histone H3-S10 phosphorylation(GO:0043987) |
0.1 | 2.6 | GO:0048266 | behavioral response to pain(GO:0048266) |
0.1 | 2.5 | GO:0070534 | protein K63-linked ubiquitination(GO:0070534) |
0.1 | 0.2 | GO:0003094 | glomerular filtration(GO:0003094) renal filtration(GO:0097205) |
0.1 | 0.8 | GO:0070601 | centromeric sister chromatid cohesion(GO:0070601) |
0.1 | 1.7 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
0.1 | 0.3 | GO:1902952 | positive regulation of dendritic spine maintenance(GO:1902952) |
0.1 | 3.4 | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146) |
0.1 | 0.3 | GO:0035526 | retrograde transport, plasma membrane to Golgi(GO:0035526) |
0.1 | 3.2 | GO:0018279 | protein N-linked glycosylation via asparagine(GO:0018279) |
0.1 | 0.2 | GO:0071677 | positive regulation of mononuclear cell migration(GO:0071677) |
0.1 | 0.3 | GO:0019858 | cytosine metabolic process(GO:0019858) |
0.1 | 0.4 | GO:1904426 | positive regulation of GTP binding(GO:1904426) regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453) |
0.1 | 0.7 | GO:0098967 | exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967) |
0.1 | 1.5 | GO:0030011 | maintenance of cell polarity(GO:0030011) |
0.1 | 2.8 | GO:0007097 | nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023) |
0.1 | 2.8 | GO:0010866 | regulation of triglyceride biosynthetic process(GO:0010866) |
0.1 | 0.5 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
0.1 | 0.9 | GO:0032482 | Rab protein signal transduction(GO:0032482) |
0.1 | 0.7 | GO:0099640 | axo-dendritic protein transport(GO:0099640) |
0.1 | 0.8 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
0.1 | 0.2 | GO:0010692 | regulation of alkaline phosphatase activity(GO:0010692) positive regulation of alkaline phosphatase activity(GO:0010694) |
0.1 | 5.7 | GO:0007492 | endoderm development(GO:0007492) |
0.1 | 2.0 | GO:0034453 | microtubule anchoring(GO:0034453) |
0.1 | 1.1 | GO:0051601 | exocyst localization(GO:0051601) |
0.1 | 1.0 | GO:0021942 | radial glia guided migration of Purkinje cell(GO:0021942) |
0.1 | 2.0 | GO:0070536 | protein K63-linked deubiquitination(GO:0070536) |
0.1 | 0.5 | GO:0001837 | epithelial to mesenchymal transition(GO:0001837) |
0.1 | 0.6 | GO:0042276 | error-prone translesion synthesis(GO:0042276) |
0.1 | 0.4 | GO:2000049 | positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049) |
0.1 | 2.0 | GO:0035641 | locomotory exploration behavior(GO:0035641) |
0.1 | 0.7 | GO:1902187 | negative regulation of viral release from host cell(GO:1902187) |
0.1 | 0.2 | GO:0035964 | COPI-coated vesicle budding(GO:0035964) |
0.1 | 3.6 | GO:0046513 | ceramide biosynthetic process(GO:0046513) |
0.1 | 0.5 | GO:0070070 | proton-transporting V-type ATPase complex assembly(GO:0070070) |
0.1 | 0.6 | GO:0014842 | regulation of skeletal muscle satellite cell proliferation(GO:0014842) regulation of skeletal muscle cell proliferation(GO:0014857) |
0.1 | 2.4 | GO:0007638 | mechanosensory behavior(GO:0007638) |
0.1 | 5.3 | GO:0030203 | glycosaminoglycan metabolic process(GO:0030203) |
0.1 | 0.3 | GO:0098532 | histone H3-K27 trimethylation(GO:0098532) |
0.1 | 4.5 | GO:0045839 | negative regulation of mitotic nuclear division(GO:0045839) |
0.1 | 1.0 | GO:0070830 | apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830) |
0.1 | 1.9 | GO:0035909 | aorta morphogenesis(GO:0035909) |
0.1 | 0.6 | GO:2000628 | regulation of miRNA metabolic process(GO:2000628) |
0.1 | 3.6 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
0.1 | 0.2 | GO:1904742 | regulation of telomeric DNA binding(GO:1904742) |
0.1 | 0.5 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
0.1 | 9.2 | GO:0007596 | blood coagulation(GO:0007596) |
0.1 | 0.4 | GO:1900095 | regulation of dosage compensation by inactivation of X chromosome(GO:1900095) |
0.1 | 0.5 | GO:0030262 | apoptotic nuclear changes(GO:0030262) |
0.1 | 1.0 | GO:0080182 | histone H3-K4 trimethylation(GO:0080182) |
0.1 | 0.4 | GO:1903056 | positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056) |
0.1 | 2.2 | GO:0002011 | morphogenesis of an epithelial sheet(GO:0002011) |
0.1 | 0.5 | GO:0019254 | carnitine metabolic process, CoA-linked(GO:0019254) |
0.1 | 0.3 | GO:0000117 | regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117) |
0.1 | 0.5 | GO:0090527 | actin filament reorganization(GO:0090527) |
0.1 | 0.5 | GO:1903818 | positive regulation of voltage-gated potassium channel activity(GO:1903818) |
0.1 | 2.6 | GO:0007628 | adult walking behavior(GO:0007628) |
0.1 | 0.8 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
0.1 | 0.3 | GO:0098706 | ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706) |
0.1 | 0.3 | GO:1901386 | negative regulation of voltage-gated calcium channel activity(GO:1901386) |
0.1 | 0.3 | GO:0008655 | pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097) |
0.1 | 0.4 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
0.1 | 3.4 | GO:0006893 | Golgi to plasma membrane transport(GO:0006893) |
0.1 | 0.1 | GO:0048619 | embryonic hindgut morphogenesis(GO:0048619) |
0.1 | 0.9 | GO:0009081 | branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083) |
0.1 | 0.2 | GO:0019530 | taurine metabolic process(GO:0019530) |
0.1 | 0.2 | GO:0031000 | response to caffeine(GO:0031000) |
0.1 | 0.6 | GO:0051255 | spindle midzone assembly(GO:0051255) mitotic spindle midzone assembly(GO:0051256) |
0.1 | 0.2 | GO:0007144 | female meiosis I(GO:0007144) |
0.1 | 0.1 | GO:0070213 | protein auto-ADP-ribosylation(GO:0070213) |
0.1 | 0.6 | GO:0061469 | regulation of type B pancreatic cell proliferation(GO:0061469) |
0.1 | 0.1 | GO:0070162 | adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163) negative regulation of adiponectin secretion(GO:0070164) |
0.1 | 0.2 | GO:0048254 | snoRNA localization(GO:0048254) |
0.1 | 0.3 | GO:0019532 | oxalate transport(GO:0019532) |
0.1 | 0.1 | GO:0060025 | regulation of synaptic activity(GO:0060025) |
0.1 | 0.3 | GO:1903715 | regulation of aerobic respiration(GO:1903715) |
0.1 | 1.3 | GO:0097178 | ruffle assembly(GO:0097178) |
0.1 | 0.7 | GO:0046548 | retinal rod cell development(GO:0046548) |
0.1 | 0.7 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
0.1 | 0.8 | GO:0001516 | prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457) |
0.1 | 0.4 | GO:0007168 | receptor guanylyl cyclase signaling pathway(GO:0007168) |
0.1 | 1.0 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
0.1 | 0.1 | GO:1901165 | positive regulation of trophoblast cell migration(GO:1901165) |
0.1 | 0.4 | GO:0003215 | cardiac right ventricle morphogenesis(GO:0003215) |
0.1 | 0.8 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
0.1 | 0.6 | GO:0071300 | cellular response to retinoic acid(GO:0071300) |
0.1 | 0.8 | GO:0003170 | heart valve development(GO:0003170) |
0.1 | 0.4 | GO:0033603 | positive regulation of dopamine secretion(GO:0033603) |
0.1 | 0.3 | GO:0016557 | peroxisome membrane biogenesis(GO:0016557) |
0.1 | 4.0 | GO:0016579 | protein deubiquitination(GO:0016579) |
0.1 | 2.2 | GO:0030500 | regulation of bone mineralization(GO:0030500) |
0.0 | 1.5 | GO:0007520 | myoblast fusion(GO:0007520) |
0.0 | 0.2 | GO:0043402 | glucocorticoid mediated signaling pathway(GO:0043402) |
0.0 | 0.3 | GO:0040016 | embryonic cleavage(GO:0040016) |
0.0 | 0.1 | GO:0016256 | N-glycan processing to lysosome(GO:0016256) |
0.0 | 0.1 | GO:0048496 | maintenance of organ identity(GO:0048496) |
0.0 | 1.4 | GO:0051646 | mitochondrion localization(GO:0051646) |
0.0 | 2.4 | GO:0000910 | cytokinesis(GO:0000910) |
0.0 | 5.9 | GO:0007224 | smoothened signaling pathway(GO:0007224) |
0.0 | 0.3 | GO:0035247 | peptidyl-arginine omega-N-methylation(GO:0035247) |
0.0 | 0.5 | GO:0007190 | activation of adenylate cyclase activity(GO:0007190) |
0.0 | 0.3 | GO:0034312 | diol biosynthetic process(GO:0034312) |
0.0 | 0.2 | GO:1901838 | positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838) |
0.0 | 3.4 | GO:0051092 | positive regulation of NF-kappaB transcription factor activity(GO:0051092) |
0.0 | 0.2 | GO:0016266 | O-glycan processing(GO:0016266) |
0.0 | 0.2 | GO:0006590 | thyroid hormone generation(GO:0006590) |
0.0 | 0.3 | GO:0045292 | mRNA cis splicing, via spliceosome(GO:0045292) |
0.0 | 0.2 | GO:1901339 | regulation of store-operated calcium channel activity(GO:1901339) |
0.0 | 0.5 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
0.0 | 0.3 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
0.0 | 0.1 | GO:0046340 | diacylglycerol catabolic process(GO:0046340) |
0.0 | 0.1 | GO:2000074 | regulation of type B pancreatic cell development(GO:2000074) |
0.0 | 0.3 | GO:0033572 | transferrin transport(GO:0033572) |
0.0 | 0.3 | GO:0016093 | polyprenol metabolic process(GO:0016093) |
0.0 | 4.2 | GO:0042787 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) |
0.0 | 0.4 | GO:0031987 | locomotion involved in locomotory behavior(GO:0031987) |
0.0 | 0.3 | GO:0051923 | sulfation(GO:0051923) |
0.0 | 0.8 | GO:0007026 | negative regulation of microtubule depolymerization(GO:0007026) |
0.0 | 0.2 | GO:0045579 | positive regulation of B cell differentiation(GO:0045579) |
0.0 | 0.4 | GO:1900026 | positive regulation of substrate adhesion-dependent cell spreading(GO:1900026) |
0.0 | 0.1 | GO:0045351 | type I interferon biosynthetic process(GO:0045351) |
0.0 | 0.3 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) |
0.0 | 0.4 | GO:0010447 | response to acidic pH(GO:0010447) |
0.0 | 0.1 | GO:0072395 | signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422) |
0.0 | 0.4 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
0.0 | 0.3 | GO:0030049 | muscle filament sliding(GO:0030049) |
0.0 | 0.3 | GO:0022027 | interkinetic nuclear migration(GO:0022027) |
0.0 | 0.6 | GO:1904031 | positive regulation of cyclin-dependent protein kinase activity(GO:1904031) |
0.0 | 0.5 | GO:0051443 | positive regulation of ubiquitin-protein transferase activity(GO:0051443) |
0.0 | 0.2 | GO:2000051 | negative regulation of non-canonical Wnt signaling pathway(GO:2000051) |
0.0 | 0.5 | GO:0046677 | response to antibiotic(GO:0046677) |
0.0 | 0.4 | GO:0031670 | cellular response to nutrient(GO:0031670) |
0.0 | 0.1 | GO:0019372 | lipoxygenase pathway(GO:0019372) |
0.0 | 0.6 | GO:0021799 | cerebral cortex radially oriented cell migration(GO:0021799) |
0.0 | 0.3 | GO:0035414 | negative regulation of catenin import into nucleus(GO:0035414) |
0.0 | 0.1 | GO:2000643 | positive regulation of vacuolar transport(GO:1903337) positive regulation of early endosome to late endosome transport(GO:2000643) |
0.0 | 0.4 | GO:0000731 | DNA synthesis involved in DNA repair(GO:0000731) |
0.0 | 0.1 | GO:0014043 | negative regulation of neuron maturation(GO:0014043) |
0.0 | 0.7 | GO:0003333 | amino acid transmembrane transport(GO:0003333) |
0.0 | 0.1 | GO:0035754 | B cell chemotaxis(GO:0035754) |
0.0 | 0.3 | GO:0019369 | arachidonic acid metabolic process(GO:0019369) |
0.0 | 0.1 | GO:0048318 | protein O-linked glycosylation via serine(GO:0018242) axial mesoderm development(GO:0048318) |
0.0 | 0.2 | GO:0006362 | transcription elongation from RNA polymerase I promoter(GO:0006362) |
0.0 | 0.0 | GO:0033092 | positive regulation of immature T cell proliferation(GO:0033091) positive regulation of immature T cell proliferation in thymus(GO:0033092) |
0.0 | 3.0 | GO:0007416 | synapse assembly(GO:0007416) |
0.0 | 1.1 | GO:0006367 | transcription initiation from RNA polymerase II promoter(GO:0006367) |
0.0 | 0.2 | GO:0030166 | proteoglycan biosynthetic process(GO:0030166) |
0.0 | 0.8 | GO:0045773 | positive regulation of axon extension(GO:0045773) |
0.0 | 0.1 | GO:0002544 | chronic inflammatory response(GO:0002544) |
0.0 | 0.2 | GO:0006817 | phosphate ion transport(GO:0006817) |
0.0 | 0.6 | GO:0061512 | protein localization to cilium(GO:0061512) |
0.0 | 0.5 | GO:0045070 | positive regulation of viral genome replication(GO:0045070) |
0.0 | 0.2 | GO:0008090 | retrograde axonal transport(GO:0008090) |
0.0 | 0.3 | GO:0046718 | viral entry into host cell(GO:0046718) |
0.0 | 0.1 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
0.0 | 0.2 | GO:0050901 | leukocyte tethering or rolling(GO:0050901) |
0.0 | 0.5 | GO:0010591 | regulation of lamellipodium assembly(GO:0010591) |
0.0 | 2.8 | GO:0043547 | positive regulation of GTPase activity(GO:0043547) |
0.0 | 0.1 | GO:0090051 | regulation of cell migration involved in sprouting angiogenesis(GO:0090049) negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051) negative regulation of sprouting angiogenesis(GO:1903671) |
0.0 | 0.4 | GO:0043550 | regulation of lipid kinase activity(GO:0043550) |
0.0 | 0.1 | GO:0006102 | isocitrate metabolic process(GO:0006102) |
0.0 | 0.2 | GO:0031643 | positive regulation of myelination(GO:0031643) |
0.0 | 0.4 | GO:0030818 | negative regulation of cAMP biosynthetic process(GO:0030818) |
0.0 | 0.5 | GO:1901385 | regulation of voltage-gated calcium channel activity(GO:1901385) |
0.0 | 0.7 | GO:0060395 | SMAD protein signal transduction(GO:0060395) |
0.0 | 0.1 | GO:0014029 | neural crest formation(GO:0014029) |
0.0 | 0.5 | GO:0051865 | protein autoubiquitination(GO:0051865) |
0.0 | 0.2 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
0.0 | 0.1 | GO:2000369 | regulation of clathrin-mediated endocytosis(GO:2000369) |
0.0 | 2.4 | GO:0016358 | dendrite development(GO:0016358) |
0.0 | 0.2 | GO:0015816 | glycine transport(GO:0015816) |
0.0 | 0.1 | GO:1903077 | negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376) |
0.0 | 0.1 | GO:0034720 | histone H3-K4 demethylation(GO:0034720) |
0.0 | 0.6 | GO:0008156 | negative regulation of DNA replication(GO:0008156) |
0.0 | 0.2 | GO:0035411 | catenin import into nucleus(GO:0035411) |
0.0 | 0.2 | GO:0046928 | regulation of neurotransmitter secretion(GO:0046928) |
0.0 | 0.1 | GO:0048642 | negative regulation of skeletal muscle tissue development(GO:0048642) |
0.0 | 0.1 | GO:0009435 | NAD biosynthetic process(GO:0009435) |
0.0 | 0.2 | GO:0048538 | thymus development(GO:0048538) |
0.0 | 0.2 | GO:0060043 | regulation of cardiac muscle cell proliferation(GO:0060043) |
0.0 | 0.7 | GO:0002062 | chondrocyte differentiation(GO:0002062) |
0.0 | 0.1 | GO:0035518 | histone H2A monoubiquitination(GO:0035518) |
0.0 | 0.8 | GO:0007030 | Golgi organization(GO:0007030) |
0.0 | 0.0 | GO:0032703 | negative regulation of interleukin-2 production(GO:0032703) |
0.0 | 0.3 | GO:0001523 | retinoid metabolic process(GO:0001523) |
0.0 | 0.1 | GO:0046322 | negative regulation of fatty acid oxidation(GO:0046322) |
0.0 | 0.2 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663) |
0.0 | 0.1 | GO:1902369 | negative regulation of RNA catabolic process(GO:1902369) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.8 | 11.4 | GO:0031084 | BLOC-2 complex(GO:0031084) |
2.6 | 7.7 | GO:0005927 | muscle tendon junction(GO:0005927) |
2.5 | 10.1 | GO:0019034 | viral replication complex(GO:0019034) |
2.1 | 15.0 | GO:0033263 | CORVET complex(GO:0033263) |
1.9 | 16.8 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
1.8 | 5.4 | GO:0033596 | TSC1-TSC2 complex(GO:0033596) |
1.7 | 6.6 | GO:0099569 | presynaptic cytoskeleton(GO:0099569) |
1.6 | 6.3 | GO:0034991 | nuclear meiotic cohesin complex(GO:0034991) |
1.1 | 3.3 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
1.1 | 11.1 | GO:0071141 | SMAD protein complex(GO:0071141) |
1.1 | 9.9 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
0.8 | 4.0 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
0.8 | 1.6 | GO:0098592 | cytoplasmic side of apical plasma membrane(GO:0098592) |
0.8 | 4.0 | GO:0070044 | synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044) |
0.8 | 7.8 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
0.8 | 1.6 | GO:0042581 | specific granule(GO:0042581) |
0.8 | 10.1 | GO:1990635 | proximal dendrite(GO:1990635) |
0.7 | 2.2 | GO:0098835 | presynaptic endosome(GO:0098830) presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) |
0.7 | 5.6 | GO:0034750 | Scrib-APC-beta-catenin complex(GO:0034750) |
0.7 | 4.8 | GO:0033503 | HULC complex(GO:0033503) |
0.7 | 2.0 | GO:0020018 | ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018) |
0.6 | 5.8 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
0.6 | 9.2 | GO:0043196 | varicosity(GO:0043196) |
0.6 | 2.8 | GO:0044666 | MLL3/4 complex(GO:0044666) |
0.5 | 2.7 | GO:1990037 | Lewy body core(GO:1990037) |
0.5 | 3.7 | GO:0070695 | FHF complex(GO:0070695) |
0.5 | 5.2 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
0.5 | 2.3 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
0.5 | 1.4 | GO:0070985 | TFIIK complex(GO:0070985) |
0.5 | 4.2 | GO:0000439 | core TFIIH complex(GO:0000439) |
0.4 | 2.7 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
0.4 | 1.3 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
0.4 | 4.1 | GO:0032591 | dendritic spine membrane(GO:0032591) |
0.4 | 2.4 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
0.4 | 2.0 | GO:0097441 | basilar dendrite(GO:0097441) |
0.4 | 4.3 | GO:0033179 | proton-transporting V-type ATPase, V0 domain(GO:0033179) |
0.4 | 1.5 | GO:0032280 | symmetric synapse(GO:0032280) |
0.4 | 13.6 | GO:0035861 | site of double-strand break(GO:0035861) |
0.4 | 7.1 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
0.4 | 5.7 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
0.3 | 2.4 | GO:0071203 | WASH complex(GO:0071203) |
0.3 | 3.5 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
0.3 | 1.0 | GO:0031045 | dense core granule(GO:0031045) |
0.3 | 5.1 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
0.3 | 1.9 | GO:0070776 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
0.3 | 5.5 | GO:0010369 | chromocenter(GO:0010369) |
0.3 | 2.1 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
0.3 | 2.3 | GO:0005787 | signal peptidase complex(GO:0005787) |
0.3 | 0.9 | GO:0097629 | extrinsic component of omegasome membrane(GO:0097629) |
0.3 | 9.2 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
0.3 | 3.6 | GO:0042405 | nuclear inclusion body(GO:0042405) |
0.3 | 2.2 | GO:0042589 | zymogen granule membrane(GO:0042589) |
0.3 | 3.6 | GO:0030057 | desmosome(GO:0030057) |
0.3 | 2.5 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
0.3 | 2.2 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
0.3 | 1.8 | GO:0005827 | polar microtubule(GO:0005827) |
0.3 | 1.0 | GO:0043202 | lysosomal lumen(GO:0043202) |
0.2 | 2.7 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
0.2 | 0.5 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
0.2 | 3.4 | GO:0043203 | axon hillock(GO:0043203) |
0.2 | 0.7 | GO:0031083 | BLOC-1 complex(GO:0031083) |
0.2 | 1.0 | GO:0097487 | vacuolar lumen(GO:0005775) multivesicular body membrane(GO:0032585) multivesicular body, internal vesicle(GO:0097487) |
0.2 | 1.9 | GO:0072687 | meiotic spindle(GO:0072687) |
0.2 | 0.7 | GO:1990075 | periciliary membrane compartment(GO:1990075) |
0.2 | 0.9 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
0.2 | 0.7 | GO:0005899 | insulin receptor complex(GO:0005899) |
0.2 | 1.0 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
0.2 | 2.9 | GO:0005869 | dynactin complex(GO:0005869) |
0.2 | 1.0 | GO:0097361 | CIA complex(GO:0097361) |
0.2 | 0.4 | GO:0000801 | central element(GO:0000801) |
0.2 | 7.1 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
0.2 | 4.2 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
0.2 | 1.0 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
0.2 | 3.3 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
0.2 | 1.7 | GO:0042582 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
0.2 | 0.7 | GO:0044308 | axonal spine(GO:0044308) |
0.2 | 2.9 | GO:0030008 | TRAPP complex(GO:0030008) |
0.2 | 4.0 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
0.2 | 1.4 | GO:0046581 | intercellular canaliculus(GO:0046581) |
0.2 | 2.1 | GO:0030061 | mitochondrial crista(GO:0030061) |
0.2 | 1.3 | GO:0005785 | signal recognition particle receptor complex(GO:0005785) |
0.2 | 10.4 | GO:0005905 | clathrin-coated pit(GO:0005905) |
0.2 | 0.6 | GO:0051286 | cell tip(GO:0051286) |
0.2 | 1.4 | GO:0000813 | ESCRT I complex(GO:0000813) |
0.2 | 0.5 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
0.1 | 3.2 | GO:0005797 | Golgi medial cisterna(GO:0005797) |
0.1 | 1.8 | GO:0044754 | autolysosome(GO:0044754) |
0.1 | 0.1 | GO:0010009 | cytoplasmic side of endosome membrane(GO:0010009) cytoplasmic side of early endosome membrane(GO:0098559) |
0.1 | 0.7 | GO:0097422 | tubular endosome(GO:0097422) |
0.1 | 3.0 | GO:0030667 | secretory granule membrane(GO:0030667) |
0.1 | 2.6 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.1 | 4.1 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
0.1 | 37.2 | GO:0000139 | Golgi membrane(GO:0000139) |
0.1 | 1.4 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
0.1 | 26.0 | GO:0098852 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
0.1 | 23.9 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
0.1 | 0.3 | GO:0001739 | sex chromatin(GO:0001739) |
0.1 | 2.4 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
0.1 | 0.8 | GO:0005883 | neurofilament(GO:0005883) |
0.1 | 0.9 | GO:0090571 | RNA polymerase II transcription repressor complex(GO:0090571) |
0.1 | 4.8 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
0.1 | 1.9 | GO:0035102 | PRC1 complex(GO:0035102) |
0.1 | 3.2 | GO:0071339 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
0.1 | 0.4 | GO:0097574 | lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795) photoreceptor cell terminal bouton(GO:1990796) |
0.1 | 2.8 | GO:0035371 | microtubule plus-end(GO:0035371) |
0.1 | 0.8 | GO:0031415 | NatA complex(GO:0031415) |
0.1 | 2.2 | GO:0000242 | pericentriolar material(GO:0000242) |
0.1 | 0.4 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
0.1 | 0.6 | GO:0005796 | Golgi lumen(GO:0005796) |
0.1 | 0.4 | GO:0035032 | phosphatidylinositol 3-kinase complex, class III(GO:0035032) |
0.1 | 4.2 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
0.1 | 0.9 | GO:0045252 | dihydrolipoyl dehydrogenase complex(GO:0045240) oxoglutarate dehydrogenase complex(GO:0045252) |
0.1 | 0.4 | GO:0001651 | dense fibrillar component(GO:0001651) |
0.1 | 1.0 | GO:0090543 | Flemming body(GO:0090543) |
0.1 | 6.7 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
0.1 | 0.7 | GO:0071437 | invadopodium(GO:0071437) |
0.1 | 4.2 | GO:0005776 | autophagosome(GO:0005776) |
0.1 | 0.5 | GO:0030665 | clathrin-coated vesicle membrane(GO:0030665) |
0.1 | 9.0 | GO:0055037 | recycling endosome(GO:0055037) |
0.1 | 0.3 | GO:1990769 | proximal neuron projection(GO:1990769) |
0.1 | 2.2 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
0.1 | 0.5 | GO:0005955 | calcineurin complex(GO:0005955) |
0.1 | 0.3 | GO:0097443 | sorting endosome(GO:0097443) |
0.1 | 0.5 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
0.1 | 0.6 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
0.1 | 5.9 | GO:0030139 | endocytic vesicle(GO:0030139) |
0.1 | 4.4 | GO:0016528 | sarcoplasm(GO:0016528) |
0.1 | 1.7 | GO:0030673 | axolemma(GO:0030673) |
0.1 | 0.5 | GO:0002178 | palmitoyltransferase complex(GO:0002178) |
0.1 | 0.6 | GO:0036157 | outer dynein arm(GO:0036157) |
0.1 | 3.3 | GO:0016459 | myosin complex(GO:0016459) |
0.1 | 0.2 | GO:0098554 | cytoplasmic side of endoplasmic reticulum membrane(GO:0098554) |
0.1 | 0.4 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
0.1 | 0.7 | GO:1904949 | ATPase complex(GO:1904949) |
0.1 | 0.4 | GO:0030119 | AP-type membrane coat adaptor complex(GO:0030119) |
0.1 | 2.8 | GO:0009925 | basal plasma membrane(GO:0009925) |
0.1 | 2.4 | GO:0034707 | chloride channel complex(GO:0034707) |
0.1 | 2.1 | GO:0090544 | BAF-type complex(GO:0090544) |
0.1 | 0.7 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
0.1 | 0.5 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
0.1 | 1.6 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
0.1 | 1.0 | GO:0060077 | inhibitory synapse(GO:0060077) |
0.1 | 0.8 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
0.1 | 0.2 | GO:0030056 | hemidesmosome(GO:0030056) H zone(GO:0031673) |
0.1 | 0.8 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
0.1 | 0.2 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
0.0 | 9.6 | GO:0030427 | site of polarized growth(GO:0030427) |
0.0 | 5.1 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
0.0 | 0.5 | GO:0031209 | SCAR complex(GO:0031209) |
0.0 | 5.6 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
0.0 | 2.9 | GO:0005770 | late endosome(GO:0005770) |
0.0 | 1.0 | GO:0030659 | cytoplasmic vesicle membrane(GO:0030659) |
0.0 | 0.4 | GO:0098827 | endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827) |
0.0 | 0.3 | GO:0051233 | spindle midzone(GO:0051233) |
0.0 | 0.8 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
0.0 | 1.1 | GO:0035145 | exon-exon junction complex(GO:0035145) |
0.0 | 2.3 | GO:0030027 | lamellipodium(GO:0030027) |
0.0 | 0.6 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
0.0 | 1.8 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
0.0 | 0.3 | GO:0031616 | spindle pole centrosome(GO:0031616) |
0.0 | 0.1 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
0.0 | 0.3 | GO:0031258 | lamellipodium membrane(GO:0031258) |
0.0 | 0.5 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
0.0 | 0.7 | GO:0001772 | immunological synapse(GO:0001772) |
0.0 | 0.2 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
0.0 | 0.4 | GO:0043034 | costamere(GO:0043034) |
0.0 | 0.2 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
0.0 | 5.2 | GO:0045211 | postsynaptic membrane(GO:0045211) |
0.0 | 0.2 | GO:0032300 | mismatch repair complex(GO:0032300) |
0.0 | 0.1 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
0.0 | 0.2 | GO:0070187 | telosome(GO:0070187) |
0.0 | 0.6 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
0.0 | 0.3 | GO:0005686 | U2 snRNP(GO:0005686) |
0.0 | 0.1 | GO:0048269 | methionine adenosyltransferase complex(GO:0048269) |
0.0 | 0.1 | GO:0005967 | mitochondrial pyruvate dehydrogenase complex(GO:0005967) |
0.0 | 0.3 | GO:0036038 | MKS complex(GO:0036038) |
0.0 | 1.4 | GO:0043204 | perikaryon(GO:0043204) |
0.0 | 5.6 | GO:0030424 | axon(GO:0030424) |
0.0 | 0.8 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
0.0 | 7.7 | GO:0045202 | synapse(GO:0045202) |
0.0 | 0.6 | GO:0042383 | sarcolemma(GO:0042383) |
0.0 | 0.8 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
0.0 | 0.8 | GO:0001669 | acrosomal vesicle(GO:0001669) |
0.0 | 0.3 | GO:0005614 | interstitial matrix(GO:0005614) |
0.0 | 1.3 | GO:0005802 | trans-Golgi network(GO:0005802) |
0.0 | 0.2 | GO:0097539 | ciliary transition fiber(GO:0097539) |
0.0 | 5.9 | GO:0005773 | vacuole(GO:0005773) |
0.0 | 0.1 | GO:0036513 | Derlin-1 retrotranslocation complex(GO:0036513) |
0.0 | 0.7 | GO:0072562 | blood microparticle(GO:0072562) |
0.0 | 0.2 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
0.0 | 0.6 | GO:0005903 | brush border(GO:0005903) |
0.0 | 0.2 | GO:0005839 | proteasome core complex(GO:0005839) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
6.4 | 19.3 | GO:0004489 | methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489) |
3.4 | 10.3 | GO:0043682 | copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682) |
2.9 | 8.6 | GO:0035500 | MH2 domain binding(GO:0035500) |
2.0 | 45.6 | GO:0005351 | sugar:proton symporter activity(GO:0005351) |
1.7 | 12.0 | GO:0033592 | RNA strand annealing activity(GO:0033592) |
1.4 | 8.3 | GO:0016401 | palmitoyl-CoA oxidase activity(GO:0016401) |
1.2 | 8.7 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
1.2 | 4.8 | GO:0000099 | sulfur amino acid transmembrane transporter activity(GO:0000099) |
1.2 | 6.0 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
1.2 | 19.0 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
1.2 | 3.5 | GO:0015173 | hydrogen:amino acid symporter activity(GO:0005280) aromatic amino acid transmembrane transporter activity(GO:0015173) |
1.1 | 11.9 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
1.0 | 4.0 | GO:0005483 | soluble NSF attachment protein activity(GO:0005483) |
1.0 | 3.9 | GO:0004741 | [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741) |
1.0 | 4.9 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
1.0 | 2.9 | GO:0046969 | histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969) |
1.0 | 5.8 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
0.9 | 21.0 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
0.9 | 4.6 | GO:0042289 | MHC class II protein binding(GO:0042289) |
0.9 | 3.6 | GO:0005008 | hepatocyte growth factor-activated receptor activity(GO:0005008) |
0.9 | 2.6 | GO:0004574 | oligo-1,6-glucosidase activity(GO:0004574) |
0.9 | 4.3 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
0.8 | 3.3 | GO:0072345 | NAADP-sensitive calcium-release channel activity(GO:0072345) |
0.8 | 17.9 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
0.8 | 5.7 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
0.8 | 2.4 | GO:0003692 | left-handed Z-DNA binding(GO:0003692) |
0.7 | 2.8 | GO:0001602 | pancreatic polypeptide receptor activity(GO:0001602) |
0.7 | 2.0 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
0.6 | 5.2 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
0.6 | 3.1 | GO:0034602 | oxoglutarate dehydrogenase (NAD+) activity(GO:0034602) |
0.6 | 7.4 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
0.6 | 3.0 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
0.6 | 4.6 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
0.6 | 3.4 | GO:0070699 | type II activin receptor binding(GO:0070699) |
0.6 | 1.7 | GO:0036313 | phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313) |
0.5 | 2.2 | GO:0036033 | mediator complex binding(GO:0036033) |
0.5 | 6.5 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
0.5 | 2.5 | GO:0030618 | transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) |
0.5 | 5.3 | GO:0019531 | secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531) |
0.5 | 3.8 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
0.5 | 1.4 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
0.5 | 1.4 | GO:0003846 | 2-acylglycerol O-acyltransferase activity(GO:0003846) |
0.5 | 5.5 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
0.4 | 4.4 | GO:0050308 | sugar-phosphatase activity(GO:0050308) |
0.4 | 2.6 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
0.4 | 2.1 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
0.4 | 5.4 | GO:0017081 | chloride channel regulator activity(GO:0017081) |
0.4 | 3.7 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
0.4 | 7.7 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
0.4 | 0.4 | GO:0022833 | mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833) |
0.4 | 1.2 | GO:0004348 | glucosylceramidase activity(GO:0004348) |
0.4 | 1.6 | GO:0015186 | L-glutamine transmembrane transporter activity(GO:0015186) |
0.4 | 6.0 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
0.4 | 1.1 | GO:0038052 | RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052) |
0.4 | 2.9 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
0.4 | 2.2 | GO:0044547 | DNA topoisomerase binding(GO:0044547) |
0.4 | 9.7 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.4 | 5.6 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
0.3 | 3.1 | GO:0043995 | histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972) |
0.3 | 6.9 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
0.3 | 3.1 | GO:0008499 | UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499) |
0.3 | 2.0 | GO:0051185 | coenzyme transporter activity(GO:0051185) |
0.3 | 1.7 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
0.3 | 5.9 | GO:0015215 | nucleotide transmembrane transporter activity(GO:0015215) |
0.3 | 1.8 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
0.3 | 1.2 | GO:0071074 | eukaryotic initiation factor eIF2 binding(GO:0071074) |
0.3 | 1.8 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
0.3 | 0.9 | GO:0001888 | glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888) |
0.3 | 5.9 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
0.3 | 0.9 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
0.3 | 1.1 | GO:0035851 | histone deacetylase activity (H4-K16 specific)(GO:0034739) Krueppel-associated box domain binding(GO:0035851) |
0.3 | 7.0 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
0.3 | 1.1 | GO:0017095 | heparan sulfate 6-O-sulfotransferase activity(GO:0017095) |
0.3 | 5.7 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
0.3 | 1.1 | GO:0000832 | inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724) |
0.3 | 3.7 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
0.2 | 2.7 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
0.2 | 2.7 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
0.2 | 1.0 | GO:0004104 | cholinesterase activity(GO:0004104) choline binding(GO:0033265) |
0.2 | 1.9 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
0.2 | 2.4 | GO:0005375 | copper ion transmembrane transporter activity(GO:0005375) |
0.2 | 0.7 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
0.2 | 1.1 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
0.2 | 7.0 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
0.2 | 2.4 | GO:0009922 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
0.2 | 0.2 | GO:0097100 | supercoiled DNA binding(GO:0097100) |
0.2 | 5.0 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
0.2 | 6.0 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
0.2 | 0.6 | GO:0061628 | H3K27me3 modified histone binding(GO:0061628) |
0.2 | 0.2 | GO:0019203 | carbohydrate phosphatase activity(GO:0019203) |
0.2 | 0.8 | GO:0070573 | metallodipeptidase activity(GO:0070573) |
0.2 | 1.7 | GO:0004416 | hydroxyacylglutathione hydrolase activity(GO:0004416) |
0.2 | 0.6 | GO:0019912 | cyclin-dependent protein kinase activating kinase activity(GO:0019912) |
0.2 | 0.8 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
0.2 | 5.9 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
0.2 | 2.0 | GO:0004017 | adenylate kinase activity(GO:0004017) |
0.2 | 0.6 | GO:0046997 | sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997) |
0.2 | 0.6 | GO:0005436 | sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319) |
0.2 | 0.5 | GO:0004980 | melanocortin receptor activity(GO:0004977) melanocyte-stimulating hormone receptor activity(GO:0004980) |
0.2 | 0.9 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
0.2 | 4.2 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
0.2 | 1.1 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
0.2 | 17.0 | GO:0008565 | protein transporter activity(GO:0008565) |
0.2 | 0.5 | GO:0004022 | alcohol dehydrogenase (NAD) activity(GO:0004022) |
0.2 | 1.0 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
0.2 | 10.0 | GO:0005262 | calcium channel activity(GO:0005262) |
0.2 | 1.6 | GO:0047499 | calcium-independent phospholipase A2 activity(GO:0047499) |
0.2 | 1.1 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
0.2 | 6.8 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
0.2 | 1.8 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
0.2 | 6.7 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
0.1 | 1.8 | GO:0015643 | toxic substance binding(GO:0015643) |
0.1 | 0.3 | GO:0043560 | insulin receptor substrate binding(GO:0043560) |
0.1 | 0.7 | GO:1904288 | BAT3 complex binding(GO:1904288) |
0.1 | 1.9 | GO:0010181 | FMN binding(GO:0010181) |
0.1 | 7.9 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
0.1 | 0.4 | GO:0031694 | alpha-2A adrenergic receptor binding(GO:0031694) |
0.1 | 1.0 | GO:0004075 | biotin carboxylase activity(GO:0004075) |
0.1 | 0.7 | GO:0017116 | single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) |
0.1 | 11.8 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
0.1 | 3.8 | GO:0008373 | sialyltransferase activity(GO:0008373) |
0.1 | 1.5 | GO:0031005 | filamin binding(GO:0031005) |
0.1 | 2.5 | GO:0098811 | transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811) |
0.1 | 3.1 | GO:0000030 | mannosyltransferase activity(GO:0000030) |
0.1 | 5.3 | GO:0042169 | SH2 domain binding(GO:0042169) |
0.1 | 0.4 | GO:0050656 | 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656) |
0.1 | 3.2 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
0.1 | 8.5 | GO:0050660 | flavin adenine dinucleotide binding(GO:0050660) |
0.1 | 0.9 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
0.1 | 0.7 | GO:0050543 | icosatetraenoic acid binding(GO:0050543) |
0.1 | 2.4 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
0.1 | 0.5 | GO:0004092 | carnitine O-acetyltransferase activity(GO:0004092) |
0.1 | 6.2 | GO:0030971 | receptor tyrosine kinase binding(GO:0030971) |
0.1 | 1.6 | GO:0004576 | oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
0.1 | 1.3 | GO:0015250 | water channel activity(GO:0015250) |
0.1 | 0.8 | GO:0001609 | G-protein coupled adenosine receptor activity(GO:0001609) heterotrimeric G-protein binding(GO:0032795) |
0.1 | 0.4 | GO:0004661 | protein geranylgeranyltransferase activity(GO:0004661) |
0.1 | 9.7 | GO:0019905 | syntaxin binding(GO:0019905) |
0.1 | 0.7 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
0.1 | 0.7 | GO:0004303 | estradiol 17-beta-dehydrogenase activity(GO:0004303) |
0.1 | 0.6 | GO:0016308 | 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308) |
0.1 | 1.7 | GO:0005234 | extracellular-glutamate-gated ion channel activity(GO:0005234) |
0.1 | 0.4 | GO:0016833 | oxo-acid-lyase activity(GO:0016833) |
0.1 | 2.4 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
0.1 | 0.3 | GO:0051425 | PTB domain binding(GO:0051425) |
0.1 | 0.9 | GO:0042288 | MHC class I protein binding(GO:0042288) |
0.1 | 0.3 | GO:0004301 | epoxide hydrolase activity(GO:0004301) |
0.1 | 3.9 | GO:0016790 | thiolester hydrolase activity(GO:0016790) |
0.1 | 3.4 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
0.1 | 0.5 | GO:0032051 | clathrin light chain binding(GO:0032051) |
0.1 | 2.0 | GO:0003785 | actin monomer binding(GO:0003785) |
0.1 | 1.0 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) |
0.1 | 1.1 | GO:0030331 | estrogen receptor binding(GO:0030331) |
0.1 | 0.4 | GO:0030332 | cyclin binding(GO:0030332) |
0.1 | 12.4 | GO:0035091 | phosphatidylinositol binding(GO:0035091) |
0.1 | 41.2 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
0.1 | 0.2 | GO:0016716 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716) |
0.1 | 1.7 | GO:0005521 | lamin binding(GO:0005521) |
0.1 | 8.8 | GO:0030674 | protein binding, bridging(GO:0030674) |
0.1 | 3.6 | GO:0008235 | metalloexopeptidase activity(GO:0008235) |
0.1 | 0.8 | GO:0070569 | uridylyltransferase activity(GO:0070569) |
0.1 | 2.3 | GO:0043394 | proteoglycan binding(GO:0043394) |
0.1 | 0.4 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
0.1 | 0.7 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
0.1 | 0.2 | GO:0036004 | GAF domain binding(GO:0036004) |
0.1 | 0.3 | GO:0042285 | UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285) |
0.1 | 0.7 | GO:0051021 | GDP-dissociation inhibitor binding(GO:0051021) |
0.1 | 0.6 | GO:0004622 | lysophospholipase activity(GO:0004622) |
0.1 | 0.2 | GO:0035243 | protein-arginine omega-N symmetric methyltransferase activity(GO:0035243) |
0.1 | 0.1 | GO:0048156 | tau protein binding(GO:0048156) |
0.1 | 0.3 | GO:0004849 | uridine kinase activity(GO:0004849) |
0.1 | 3.0 | GO:0015485 | cholesterol binding(GO:0015485) |
0.1 | 0.6 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
0.1 | 1.2 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
0.1 | 1.0 | GO:0051787 | misfolded protein binding(GO:0051787) |
0.1 | 0.5 | GO:0016717 | oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717) |
0.1 | 0.2 | GO:0019237 | centromeric DNA binding(GO:0019237) |
0.1 | 1.8 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
0.1 | 4.5 | GO:0005249 | voltage-gated potassium channel activity(GO:0005249) |
0.1 | 0.5 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
0.1 | 1.2 | GO:0005158 | insulin receptor binding(GO:0005158) |
0.1 | 0.8 | GO:0035497 | cAMP response element binding(GO:0035497) |
0.1 | 0.5 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
0.1 | 9.1 | GO:0008017 | microtubule binding(GO:0008017) |
0.1 | 0.4 | GO:0001094 | TFIID-class transcription factor binding(GO:0001094) |
0.1 | 0.5 | GO:0004679 | AMP-activated protein kinase activity(GO:0004679) |
0.1 | 1.7 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
0.1 | 0.5 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
0.0 | 1.1 | GO:0008327 | methyl-CpG binding(GO:0008327) |
0.0 | 1.0 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
0.0 | 0.2 | GO:0050347 | trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347) |
0.0 | 1.3 | GO:0051018 | protein kinase A binding(GO:0051018) |
0.0 | 1.2 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.0 | 4.9 | GO:0003774 | motor activity(GO:0003774) |
0.0 | 0.4 | GO:0031702 | angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702) |
0.0 | 0.1 | GO:0016880 | acid-ammonia (or amide) ligase activity(GO:0016880) |
0.0 | 0.2 | GO:0015143 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
0.0 | 0.2 | GO:0030144 | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144) |
0.0 | 1.1 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
0.0 | 0.8 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
0.0 | 0.1 | GO:0001042 | RNA polymerase I core binding(GO:0001042) |
0.0 | 0.1 | GO:0003976 | UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976) |
0.0 | 0.2 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
0.0 | 3.3 | GO:0005125 | cytokine activity(GO:0005125) |
0.0 | 0.1 | GO:0017050 | sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050) |
0.0 | 0.1 | GO:0004667 | prostaglandin-D synthase activity(GO:0004667) |
0.0 | 0.3 | GO:0000268 | peroxisome targeting sequence binding(GO:0000268) |
0.0 | 0.6 | GO:0005044 | scavenger receptor activity(GO:0005044) |
0.0 | 0.3 | GO:0016229 | steroid dehydrogenase activity(GO:0016229) |
0.0 | 0.6 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
0.0 | 0.7 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
0.0 | 1.4 | GO:0035064 | methylated histone binding(GO:0035064) |
0.0 | 0.4 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.0 | 0.7 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
0.0 | 0.1 | GO:0042134 | rRNA primary transcript binding(GO:0042134) |
0.0 | 0.1 | GO:0032453 | histone demethylase activity (H3-K4 specific)(GO:0032453) |
0.0 | 1.9 | GO:0008094 | DNA-dependent ATPase activity(GO:0008094) |
0.0 | 0.1 | GO:0070568 | guanylyltransferase activity(GO:0070568) |
0.0 | 0.3 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
0.0 | 0.1 | GO:0004449 | isocitrate dehydrogenase (NAD+) activity(GO:0004449) |
0.0 | 0.1 | GO:0004065 | arylsulfatase activity(GO:0004065) |
0.0 | 0.3 | GO:0036459 | thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005) |
0.0 | 0.2 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
0.0 | 0.1 | GO:0035242 | histone-arginine N-methyltransferase activity(GO:0008469) arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274) protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242) |
0.0 | 0.4 | GO:1901505 | carbohydrate derivative transporter activity(GO:1901505) |
0.0 | 0.3 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
0.0 | 0.1 | GO:0001849 | complement component C1q binding(GO:0001849) |
0.0 | 0.2 | GO:0015187 | glycine transmembrane transporter activity(GO:0015187) |
0.0 | 0.3 | GO:0000182 | rDNA binding(GO:0000182) |
0.0 | 0.5 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
0.0 | 0.6 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
0.0 | 0.1 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
0.0 | 0.2 | GO:0016018 | cyclosporin A binding(GO:0016018) |
0.0 | 0.1 | GO:0034711 | inhibin binding(GO:0034711) |
0.0 | 2.8 | GO:0051015 | actin filament binding(GO:0051015) |
0.0 | 0.6 | GO:0008378 | galactosyltransferase activity(GO:0008378) |
0.0 | 0.8 | GO:0070063 | RNA polymerase binding(GO:0070063) |
0.0 | 0.1 | GO:0033691 | sialic acid binding(GO:0033691) |
0.0 | 0.4 | GO:0070412 | R-SMAD binding(GO:0070412) |
0.0 | 0.1 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
0.0 | 0.1 | GO:0044548 | S100 protein binding(GO:0044548) |
0.0 | 0.1 | GO:0016971 | flavin-linked sulfhydryl oxidase activity(GO:0016971) |
0.0 | 0.5 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
0.0 | 0.3 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
0.0 | 0.6 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
0.0 | 0.4 | GO:0000983 | transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983) |
0.0 | 0.1 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
0.0 | 0.6 | GO:0048365 | Rac GTPase binding(GO:0048365) |
0.0 | 0.2 | GO:0015459 | potassium channel regulator activity(GO:0015459) |
0.0 | 4.6 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
0.0 | 0.4 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
0.0 | 0.2 | GO:0004659 | prenyltransferase activity(GO:0004659) |
0.0 | 0.2 | GO:0030957 | Tat protein binding(GO:0030957) |
0.0 | 0.3 | GO:0016881 | acid-amino acid ligase activity(GO:0016881) |
0.0 | 0.1 | GO:0016618 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
0.0 | 1.3 | GO:0017137 | Rab GTPase binding(GO:0017137) |
0.0 | 0.3 | GO:0000149 | SNARE binding(GO:0000149) |
0.0 | 0.4 | GO:0046875 | ephrin receptor binding(GO:0046875) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 0.7 | SA_G2_AND_M_PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
0.3 | 17.7 | ST_JNK_MAPK_PATHWAY | JNK MAPK Pathway |
0.3 | 1.1 | PID_FRA_PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
0.2 | 2.4 | PID_CIRCADIAN_PATHWAY | Circadian rhythm pathway |
0.2 | 5.5 | ST_GRANULE_CELL_SURVIVAL_PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
0.2 | 0.7 | PID_RETINOIC_ACID_PATHWAY | Retinoic acid receptors-mediated signaling |
0.2 | 2.0 | ST_G_ALPHA_S_PATHWAY | G alpha s Pathway |
0.2 | 12.1 | PID_LKB1_PATHWAY | LKB1 signaling events |
0.2 | 3.6 | ST_GA12_PATHWAY | G alpha 12 Pathway |
0.2 | 0.8 | PID_IFNG_PATHWAY | IFN-gamma pathway |
0.1 | 9.2 | PID_AJDISS_2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
0.1 | 1.0 | PID_ATF2_PATHWAY | ATF-2 transcription factor network |
0.1 | 6.8 | PID_IL4_2PATHWAY | IL4-mediated signaling events |
0.1 | 5.6 | PID_IL2_1PATHWAY | IL2-mediated signaling events |
0.1 | 1.9 | PID_RB_1PATHWAY | Regulation of retinoblastoma protein |
0.1 | 3.2 | PID_CD40_PATHWAY | CD40/CD40L signaling |
0.1 | 2.8 | PID_GLYPICAN_1PATHWAY | Glypican 1 network |
0.1 | 1.7 | PID_ATM_PATHWAY | ATM pathway |
0.1 | 1.4 | PID_RANBP2_PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
0.1 | 0.9 | PID_IL2_PI3K_PATHWAY | IL2 signaling events mediated by PI3K |
0.1 | 3.7 | PID_FOXO_PATHWAY | FoxO family signaling |
0.1 | 4.4 | PID_P73PATHWAY | p73 transcription factor network |
0.1 | 2.6 | PID_RAS_PATHWAY | Regulation of Ras family activation |
0.1 | 0.6 | SA_MMP_CYTOKINE_CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
0.1 | 2.6 | PID_IL12_2PATHWAY | IL12-mediated signaling events |
0.1 | 1.1 | PID_ERB_GENOMIC_PATHWAY | Validated nuclear estrogen receptor beta network |
0.1 | 0.9 | PID_ECADHERIN_KERATINOCYTE_PATHWAY | E-cadherin signaling in keratinocytes |
0.1 | 1.9 | PID_AURORA_A_PATHWAY | Aurora A signaling |
0.1 | 2.7 | PID_HES_HEY_PATHWAY | Notch-mediated HES/HEY network |
0.1 | 1.6 | PID_REELIN_PATHWAY | Reelin signaling pathway |
0.0 | 1.5 | SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES | Genes related to the insulin receptor pathway |
0.0 | 3.9 | PID_ERBB1_DOWNSTREAM_PATHWAY | ErbB1 downstream signaling |
0.0 | 0.2 | PID_MET_PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
0.0 | 1.5 | PID_ARF6_TRAFFICKING_PATHWAY | Arf6 trafficking events |
0.0 | 0.5 | PID_LPA4_PATHWAY | LPA4-mediated signaling events |
0.0 | 4.1 | PID_P53_DOWNSTREAM_PATHWAY | Direct p53 effectors |
0.0 | 1.0 | PID_ERBB1_INTERNALIZATION_PATHWAY | Internalization of ErbB1 |
0.0 | 0.2 | PID_UPA_UPAR_PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
0.0 | 0.3 | SIG_CHEMOTAXIS | Genes related to chemotaxis |
0.0 | 2.9 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.0 | 0.1 | ST_TYPE_I_INTERFERON_PATHWAY | Type I Interferon (alpha/beta IFN) Pathway |
0.0 | 0.3 | PID_ERBB4_PATHWAY | ErbB4 signaling events |
0.0 | 1.6 | PID_AR_PATHWAY | Coregulation of Androgen receptor activity |
0.0 | 0.0 | ST_INTERFERON_GAMMA_PATHWAY | Interferon gamma pathway. |
0.0 | 0.6 | PID_VEGFR1_2_PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
0.0 | 0.2 | ST_TUMOR_NECROSIS_FACTOR_PATHWAY | Tumor Necrosis Factor Pathway. |
0.0 | 0.2 | PID_INTEGRIN2_PATHWAY | Beta2 integrin cell surface interactions |
0.0 | 0.4 | SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES | Genes related to regulation of the actin cytoskeleton |
0.0 | 0.6 | PID_AVB3_INTEGRIN_PATHWAY | Integrins in angiogenesis |
0.0 | 0.2 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 21.0 | REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING | Genes involved in Transferrin endocytosis and recycling |
0.7 | 10.4 | REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
0.6 | 10.6 | REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
0.6 | 5.7 | REACTOME_KERATAN_SULFATE_DEGRADATION | Genes involved in Keratan sulfate degradation |
0.6 | 3.4 | REACTOME_NEPHRIN_INTERACTIONS | Genes involved in Nephrin interactions |
0.5 | 6.2 | REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
0.4 | 5.8 | REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
0.4 | 8.4 | REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
0.4 | 4.5 | REACTOME_REGULATORY_RNA_PATHWAYS | Genes involved in Regulatory RNA pathways |
0.3 | 1.0 | REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G | Genes involved in Vif-mediated degradation of APOBEC3G |
0.3 | 4.0 | REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
0.3 | 2.7 | REACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS | Genes involved in Acetylcholine Binding And Downstream Events |
0.3 | 18.5 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
0.3 | 5.6 | REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
0.3 | 10.8 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | Genes involved in Ion transport by P-type ATPases |
0.3 | 2.3 | REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
0.3 | 6.6 | REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING | Genes involved in Growth hormone receptor signaling |
0.2 | 5.2 | REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
0.2 | 9.9 | REACTOME_FORMATION_OF_RNA_POL_II_ELONGATION_COMPLEX_ | Genes involved in Formation of RNA Pol II elongation complex |
0.2 | 0.4 | REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
0.2 | 4.6 | REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS | Genes involved in Regulation of gene expression in beta cells |
0.2 | 1.4 | REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
0.2 | 2.9 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
0.2 | 1.3 | REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
0.1 | 4.6 | REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
0.1 | 2.4 | REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
0.1 | 0.7 | REACTOME_ERKS_ARE_INACTIVATED | Genes involved in ERKs are inactivated |
0.1 | 4.3 | REACTOME_GLYCOLYSIS | Genes involved in Glycolysis |
0.1 | 1.5 | REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX | Genes involved in Association of licensing factors with the pre-replicative complex |
0.1 | 1.7 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PC | Genes involved in Acyl chain remodelling of PC |
0.1 | 3.2 | REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
0.1 | 1.3 | REACTOME_CS_DS_DEGRADATION | Genes involved in CS/DS degradation |
0.1 | 2.6 | REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
0.1 | 0.2 | REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES | Genes involved in Cross-presentation of soluble exogenous antigens (endosomes) |
0.1 | 1.9 | REACTOME_RNA_POL_II_PRE_TRANSCRIPTION_EVENTS | Genes involved in RNA Polymerase II Pre-transcription Events |
0.1 | 2.2 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
0.1 | 3.9 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
0.1 | 3.6 | REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING | Genes involved in Sema4D in semaphorin signaling |
0.1 | 2.6 | REACTOME_INTERFERON_ALPHA_BETA_SIGNALING | Genes involved in Interferon alpha/beta signaling |
0.1 | 0.7 | REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR | Genes involved in Trafficking and processing of endosomal TLR |
0.1 | 2.9 | REACTOME_EGFR_DOWNREGULATION | Genes involved in EGFR downregulation |
0.1 | 9.8 | REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
0.1 | 1.5 | REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
0.1 | 1.5 | REACTOME_SIGNALING_BY_NODAL | Genes involved in Signaling by NODAL |
0.1 | 1.5 | REACTOME_DARPP_32_EVENTS | Genes involved in DARPP-32 events |
0.1 | 1.3 | REACTOME_CRMPS_IN_SEMA3A_SIGNALING | Genes involved in CRMPs in Sema3A signaling |
0.1 | 1.2 | REACTOME_ZINC_TRANSPORTERS | Genes involved in Zinc transporters |
0.1 | 1.1 | REACTOME_PURINE_SALVAGE | Genes involved in Purine salvage |
0.1 | 0.5 | REACTOME_PYRUVATE_METABOLISM_AND_CITRIC_ACID_TCA_CYCLE | Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle |
0.1 | 0.7 | REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS | Genes involved in Nucleotide-like (purinergic) receptors |
0.1 | 0.4 | REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
0.1 | 1.1 | REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING | Genes involved in Insulin Synthesis and Processing |
0.1 | 4.6 | REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS | Genes involved in Glycerophospholipid biosynthesis |
0.1 | 0.4 | REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT | Genes involved in Regulation of beta-cell development |
0.0 | 4.1 | REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS | Genes involved in Peptide ligand-binding receptors |
0.0 | 1.0 | REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
0.0 | 0.5 | REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB | Genes involved in PKA-mediated phosphorylation of CREB |
0.0 | 0.9 | REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS | Genes involved in Prolonged ERK activation events |
0.0 | 2.6 | REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION | Genes involved in MHC class II antigen presentation |
0.0 | 1.2 | REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
0.0 | 0.5 | REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS | Genes involved in Activation of BH3-only proteins |
0.0 | 0.6 | REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
0.0 | 0.3 | REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
0.0 | 1.0 | REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
0.0 | 0.4 | REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP | Genes involved in Destabilization of mRNA by KSRP |
0.0 | 1.3 | REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
0.0 | 0.8 | REACTOME_RECYCLING_PATHWAY_OF_L1 | Genes involved in Recycling pathway of L1 |
0.0 | 0.3 | REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
0.0 | 0.2 | REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION | Genes involved in FGFR4 ligand binding and activation |
0.0 | 0.5 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION | Genes involved in N-Glycan antennae elongation |
0.0 | 0.8 | REACTOME_G_ALPHA_S_SIGNALLING_EVENTS | Genes involved in G alpha (s) signalling events |
0.0 | 0.2 | REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
0.0 | 0.3 | REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
0.0 | 0.2 | REACTOME_STEROID_HORMONES | Genes involved in Steroid hormones |
0.0 | 0.4 | REACTOME_INTEGRIN_ALPHAIIB_BETA3_SIGNALING | Genes involved in Integrin alphaIIb beta3 signaling |
0.0 | 1.0 | REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION_ | Genes involved in Cyclin E associated events during G1/S transition |
0.0 | 0.2 | REACTOME_PEROXISOMAL_LIPID_METABOLISM | Genes involved in Peroxisomal lipid metabolism |
0.0 | 0.2 | REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
0.0 | 0.3 | REACTOME_SMOOTH_MUSCLE_CONTRACTION | Genes involved in Smooth Muscle Contraction |