Motif ID: Fosl2_Bach2

Z-value: 0.774

Transcription factors associated with Fosl2_Bach2:

Gene SymbolEntrez IDGene Name
Bach2 ENSMUSG00000040270.10 Bach2
Fosl2 ENSMUSG00000029135.9 Fosl2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Fosl2mm10_v2_chr5_+_32136458_321365050.711.5e-07Click!
Bach2mm10_v2_chr4_+_32238950_322389640.296.4e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Fosl2_Bach2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_33907721 6.416 ENSMUST00000115161.1
ENSMUST00000062289.8
Bend6

BEN domain containing 6

chrY_-_1286563 4.974 ENSMUST00000091190.5
Ddx3y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr14_+_65968483 4.587 ENSMUST00000022616.6
Clu
clusterin
chr18_+_32938955 4.291 ENSMUST00000042868.4
Camk4
calcium/calmodulin-dependent protein kinase IV
chr6_+_17463927 4.047 ENSMUST00000115442.1
Met
met proto-oncogene
chr2_-_45110241 3.324 ENSMUST00000177302.1
Zeb2
zinc finger E-box binding homeobox 2
chr14_+_101840602 3.220 ENSMUST00000159314.1
Lmo7
LIM domain only 7
chr3_-_88503187 3.134 ENSMUST00000120377.1
Lmna
lamin A
chr9_-_20728219 3.033 ENSMUST00000034692.7
Olfm2
olfactomedin 2
chr6_-_124769548 3.019 ENSMUST00000149652.1
ENSMUST00000112476.1
ENSMUST00000004378.8
Eno2


enolase 2, gamma neuronal


chr3_-_88503331 2.801 ENSMUST00000029699.6
Lmna
lamin A
chr2_-_36105271 2.767 ENSMUST00000112960.1
ENSMUST00000112967.5
ENSMUST00000112963.1
Lhx6


LIM homeobox protein 6


chr6_+_124996681 2.766 ENSMUST00000032479.4
Pianp
PILR alpha associated neural protein
chr6_-_97459279 2.753 ENSMUST00000113359.1
Frmd4b
FERM domain containing 4B
chr13_+_54949388 2.644 ENSMUST00000026994.7
ENSMUST00000109994.2
Unc5a

unc-5 homolog A (C. elegans)

chr7_-_105482197 2.605 ENSMUST00000047040.2
Prkcdbp
protein kinase C, delta binding protein
chr14_+_101840501 2.604 ENSMUST00000159026.1
Lmo7
LIM domain only 7
chr13_-_54611332 2.480 ENSMUST00000091609.4
Cltb
clathrin, light polypeptide (Lcb)
chr7_-_44670820 2.421 ENSMUST00000048102.7
Myh14
myosin, heavy polypeptide 14
chr13_-_54611274 2.411 ENSMUST00000049575.7
Cltb
clathrin, light polypeptide (Lcb)
chr14_+_27622433 2.363 ENSMUST00000090302.5
Erc2
ELKS/RAB6-interacting/CAST family member 2
chr2_+_156475803 2.341 ENSMUST00000029155.8
Epb4.1l1
erythrocyte protein band 4.1-like 1
chr8_+_95703037 2.337 ENSMUST00000073139.7
ENSMUST00000080666.7
Ndrg4

N-myc downstream regulated gene 4

chr1_+_165302625 2.323 ENSMUST00000111450.1
Gpr161
G protein-coupled receptor 161
chr3_+_55461758 2.291 ENSMUST00000070418.4
Dclk1
doublecortin-like kinase 1
chr1_-_180193475 2.250 ENSMUST00000160482.1
ENSMUST00000170472.1
Adck3

aarF domain containing kinase 3

chrX_-_8132770 2.232 ENSMUST00000130832.1
ENSMUST00000033506.6
ENSMUST00000115623.1
ENSMUST00000153839.1
Wdr13



WD repeat domain 13



chr9_+_60712989 2.210 ENSMUST00000038407.5
Larp6
La ribonucleoprotein domain family, member 6
chr2_+_156475844 2.164 ENSMUST00000103135.1
Epb4.1l1
erythrocyte protein band 4.1-like 1
chr7_+_126776939 2.136 ENSMUST00000038614.5
ENSMUST00000170882.1
ENSMUST00000106359.1
ENSMUST00000106357.1
ENSMUST00000145762.1
ENSMUST00000132643.1
ENSMUST00000106356.1
Ypel3






yippee-like 3 (Drosophila)






chr5_+_37050854 2.116 ENSMUST00000043794.4
Jakmip1
janus kinase and microtubule interacting protein 1
chr2_-_20943413 2.108 ENSMUST00000140230.1
Arhgap21
Rho GTPase activating protein 21
chr11_-_32222233 2.097 ENSMUST00000150381.1
ENSMUST00000144902.1
ENSMUST00000020524.8
Rhbdf1


rhomboid family 1 (Drosophila)


chr3_-_84220853 2.022 ENSMUST00000154152.1
ENSMUST00000107693.2
ENSMUST00000107695.2
Trim2


tripartite motif-containing 2


chr1_-_134235420 2.011 ENSMUST00000038191.6
ENSMUST00000086465.4
Adora1

adenosine A1 receptor

chr17_-_56133817 1.916 ENSMUST00000167545.1
Sema6b
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr9_+_50752758 1.911 ENSMUST00000034562.7
Cryab
crystallin, alpha B
chr10_+_128933782 1.905 ENSMUST00000099112.2
Itga7
integrin alpha 7
chr9_-_96752822 1.902 ENSMUST00000152594.1
Zbtb38
zinc finger and BTB domain containing 38
chr11_+_103103051 1.901 ENSMUST00000152971.1
Acbd4
acyl-Coenzyme A binding domain containing 4
chr7_+_139834148 1.899 ENSMUST00000026548.7
Gpr123
G protein-coupled receptor 123
chr2_+_25428699 1.895 ENSMUST00000102919.3
Abca2
ATP-binding cassette, sub-family A (ABC1), member 2
chr18_+_37955544 1.880 ENSMUST00000070709.2
ENSMUST00000177058.1
ENSMUST00000169360.2
ENSMUST00000163591.2
ENSMUST00000091932.5
Rell2




RELT-like 2




chr8_-_11008458 1.878 ENSMUST00000040514.6
Irs2
insulin receptor substrate 2
chr6_+_17463749 1.870 ENSMUST00000115443.1
Met
met proto-oncogene
chr2_+_32628390 1.819 ENSMUST00000156578.1
Ak1
adenylate kinase 1
chr18_-_37969742 1.774 ENSMUST00000166148.1
ENSMUST00000163131.1
ENSMUST00000043437.7
Fchsd1


FCH and double SH3 domains 1


chr14_-_36968679 1.761 ENSMUST00000067700.6
Ccser2
coiled-coil serine rich 2
chr2_-_166581969 1.730 ENSMUST00000109246.1
Prex1
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
chr1_+_33908172 1.707 ENSMUST00000182513.1
ENSMUST00000183034.1
Dst

dystonin

chr15_-_102257306 1.706 ENSMUST00000135466.1
Rarg
retinoic acid receptor, gamma
chr10_-_81407641 1.701 ENSMUST00000140916.1
Nfic
nuclear factor I/C
chr5_+_35278566 1.683 ENSMUST00000049545.5
Adra2c
adrenergic receptor, alpha 2c
chr5_+_105415738 1.681 ENSMUST00000112707.1
Lrrc8b
leucine rich repeat containing 8 family, member B
chr9_+_32224457 1.678 ENSMUST00000183121.1
Arhgap32
Rho GTPase activating protein 32
chr15_+_82275197 1.661 ENSMUST00000116423.1
Sept3
septin 3
chr8_+_12984246 1.658 ENSMUST00000110873.3
ENSMUST00000173006.1
ENSMUST00000145067.1
Mcf2l


mcf.2 transforming sequence-like


chrX_+_159840463 1.581 ENSMUST00000112451.1
ENSMUST00000112453.2
Sh3kbp1

SH3-domain kinase binding protein 1

chr16_-_22439719 1.559 ENSMUST00000079601.6
Etv5
ets variant gene 5
chr8_+_107293500 1.557 ENSMUST00000151114.1
ENSMUST00000075922.4
ENSMUST00000125721.1
Nfat5


nuclear factor of activated T cells 5


chr9_-_119977250 1.545 ENSMUST00000035101.7
Csrnp1
cysteine-serine-rich nuclear protein 1
chr18_+_37955685 1.543 ENSMUST00000169498.2
Rell2
RELT-like 2
chr1_+_75549581 1.528 ENSMUST00000154101.1
Slc4a3
solute carrier family 4 (anion exchanger), member 3
chr14_-_36968769 1.503 ENSMUST00000090024.4
Ccser2
coiled-coil serine rich 2
chr4_-_42034726 1.454 ENSMUST00000084677.2
Gm21093
predicted gene, 21093
chr1_-_6215292 1.435 ENSMUST00000097832.1
4732440D04Rik
RIKEN cDNA 4732440D04 gene
chr11_-_120630516 1.413 ENSMUST00000106181.1
Mafg
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr7_+_66365905 1.411 ENSMUST00000107486.1
Gm10974
predicted gene 10974
chr10_-_128498676 1.390 ENSMUST00000026428.3
Myl6b
myosin, light polypeptide 6B
chr2_-_29253001 1.388 ENSMUST00000071201.4
Ntng2
netrin G2
chr2_+_136713444 1.360 ENSMUST00000028727.4
ENSMUST00000110098.3
Snap25

synaptosomal-associated protein 25

chr4_-_140665891 1.349 ENSMUST00000069623.5
Arhgef10l
Rho guanine nucleotide exchange factor (GEF) 10-like
chrX_+_7722214 1.341 ENSMUST00000043045.2
ENSMUST00000116634.1
ENSMUST00000115689.3
ENSMUST00000131077.1
ENSMUST00000115688.1
ENSMUST00000116633.1
Wdr45





WD repeat domain 45





chr8_-_120228221 1.339 ENSMUST00000183235.1
A330074K22Rik
RIKEN cDNA A330074K22 gene
chr1_+_87327008 1.335 ENSMUST00000172794.1
ENSMUST00000164992.2
Gigyf2

GRB10 interacting GYF protein 2

chr5_-_124187150 1.307 ENSMUST00000161938.1
Pitpnm2
phosphatidylinositol transfer protein, membrane-associated 2
chrX_+_7722267 1.288 ENSMUST00000125991.1
ENSMUST00000148624.1
Wdr45

WD repeat domain 45

chr2_-_151632471 1.284 ENSMUST00000137936.1
ENSMUST00000146172.1
ENSMUST00000094456.3
ENSMUST00000148755.1
ENSMUST00000109875.1
ENSMUST00000028951.7
ENSMUST00000109877.3
Snph






syntaphilin






chr15_+_82274935 1.265 ENSMUST00000023095.6
Sept3
septin 3
chr4_+_138972885 1.263 ENSMUST00000123636.1
ENSMUST00000043042.3
ENSMUST00000050949.2
Tmco4


transmembrane and coiled-coil domains 4


chr15_-_102257449 1.255 ENSMUST00000043172.8
Rarg
retinoic acid receptor, gamma
chr9_+_32224246 1.253 ENSMUST00000168954.2
Arhgap32
Rho GTPase activating protein 32
chr11_+_78188422 1.202 ENSMUST00000002128.7
ENSMUST00000150941.1
Rab34

RAB34, member of RAS oncogene family

chrX_+_6415736 1.185 ENSMUST00000143641.3
Shroom4
shroom family member 4
chr3_-_85722474 1.170 ENSMUST00000119077.1
Fam160a1
family with sequence similarity 160, member A1
chr18_+_61045139 1.150 ENSMUST00000025522.4
ENSMUST00000115274.1
Pdgfrb

platelet derived growth factor receptor, beta polypeptide

chr6_+_86849488 1.143 ENSMUST00000089519.6
ENSMUST00000113668.1
Aak1

AP2 associated kinase 1

chr14_+_76476913 1.130 ENSMUST00000140251.2
Tsc22d1
TSC22 domain family, member 1
chr17_-_24644933 1.124 ENSMUST00000019684.5
Slc9a3r2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr2_+_164948219 1.121 ENSMUST00000017881.2
Mmp9
matrix metallopeptidase 9
chr10_-_64090241 1.111 ENSMUST00000133588.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr7_-_127946725 1.108 ENSMUST00000118755.1
ENSMUST00000094026.3
Prss36

protease, serine, 36

chr11_-_50210765 1.100 ENSMUST00000143379.1
ENSMUST00000015981.5
ENSMUST00000102774.4
Sqstm1


sequestosome 1


chr11_+_78188737 1.091 ENSMUST00000108322.2
Rab34
RAB34, member of RAS oncogene family
chr1_+_87327044 1.074 ENSMUST00000173173.1
Gigyf2
GRB10 interacting GYF protein 2
chr2_-_45110336 1.069 ENSMUST00000028229.6
ENSMUST00000152232.1
Zeb2

zinc finger E-box binding homeobox 2

chrX_+_73675500 1.056 ENSMUST00000171398.1
Slc6a8
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chrX_+_99975570 1.033 ENSMUST00000113779.1
ENSMUST00000113776.1
ENSMUST00000113775.1
ENSMUST00000113780.1
ENSMUST00000113778.1
ENSMUST00000113781.1
ENSMUST00000113783.1
ENSMUST00000071453.2
ENSMUST00000113777.1
Eda








ectodysplasin-A








chr11_-_120041774 1.018 ENSMUST00000103019.1
Aatk
apoptosis-associated tyrosine kinase
chr4_-_6454068 1.017 ENSMUST00000124344.1
Nsmaf
neutral sphingomyelinase (N-SMase) activation associated factor
chr7_+_30553263 0.996 ENSMUST00000044048.7
Hspb6
heat shock protein, alpha-crystallin-related, B6
chr7_+_110772604 0.977 ENSMUST00000005829.6
Ampd3
adenosine monophosphate deaminase 3
chrX_-_7740206 0.975 ENSMUST00000128289.1
Ccdc120
coiled-coil domain containing 120
chr8_-_60954726 0.968 ENSMUST00000110302.1
Clcn3
chloride channel 3
chr2_+_131909928 0.952 ENSMUST00000091288.6
Prnp
prion protein
chr10_-_81427114 0.935 ENSMUST00000078185.7
ENSMUST00000020461.8
ENSMUST00000105321.3
Nfic


nuclear factor I/C


chr8_-_105966038 0.928 ENSMUST00000116429.2
ENSMUST00000034370.9
Slc12a4

solute carrier family 12, member 4

chr15_+_77084367 0.925 ENSMUST00000181870.1
1700109K24Rik
RIKEN cDNA 1700109K24 gene
chr2_+_131909951 0.923 ENSMUST00000124100.1
ENSMUST00000136783.1
PRND

prion protein gene complex (Prn), transcript variant 1, mRNA

chr15_+_84669565 0.912 ENSMUST00000171460.1
Prr5
proline rich 5 (renal)
chr9_-_72111172 0.888 ENSMUST00000183992.1
Tcf12
transcription factor 12
chr19_-_6840590 0.867 ENSMUST00000170516.2
ENSMUST00000025903.5
Rps6ka4

ribosomal protein S6 kinase, polypeptide 4

chr16_+_17561885 0.837 ENSMUST00000171002.1
ENSMUST00000023441.4
P2rx6

purinergic receptor P2X, ligand-gated ion channel, 6

chr7_-_100547620 0.823 ENSMUST00000064334.2
D630004N19Rik
RIKEN cDNA D630004N19 gene
chr17_+_35841668 0.822 ENSMUST00000174124.1
Mdc1
mediator of DNA damage checkpoint 1
chr19_+_5447692 0.814 ENSMUST00000025850.5
Fosl1
fos-like antigen 1
chr7_+_144284385 0.813 ENSMUST00000097929.2
Shank2
SH3/ankyrin domain gene 2
chr5_+_117363513 0.810 ENSMUST00000111959.1
Wsb2
WD repeat and SOCS box-containing 2
chr10_-_64090265 0.809 ENSMUST00000105439.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr11_+_120467635 0.801 ENSMUST00000140862.1
ENSMUST00000106205.1
ENSMUST00000106203.1
ENSMUST00000026900.7
Hgs



HGF-regulated tyrosine kinase substrate



chr16_-_17722879 0.789 ENSMUST00000080936.6
ENSMUST00000012259.7
Med15

mediator complex subunit 15

chr7_-_80401707 0.764 ENSMUST00000120753.1
Furin
furin (paired basic amino acid cleaving enzyme)
chr7_+_27607997 0.752 ENSMUST00000142365.1
Akt2
thymoma viral proto-oncogene 2
chr4_+_42459563 0.749 ENSMUST00000098119.2
Gm3883
predicted gene 3883
chr6_+_135362931 0.747 ENSMUST00000032330.9
Emp1
epithelial membrane protein 1
chr14_-_31417666 0.741 ENSMUST00000100730.3
Sh3bp5
SH3-domain binding protein 5 (BTK-associated)
chr17_-_45592262 0.732 ENSMUST00000164769.1
Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr18_-_82406777 0.731 ENSMUST00000065224.6
Galr1
galanin receptor 1
chr11_+_78188806 0.723 ENSMUST00000056241.5
Rab34
RAB34, member of RAS oncogene family
chr3_+_62338344 0.722 ENSMUST00000079300.6
Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr7_-_31126945 0.720 ENSMUST00000098548.4
Scn1b
sodium channel, voltage-gated, type I, beta
chr1_-_30949756 0.709 ENSMUST00000076587.3
ENSMUST00000027232.7
Ptp4a1

protein tyrosine phosphatase 4a1

chr18_+_36559972 0.705 ENSMUST00000134146.1
Ankhd1
ankyrin repeat and KH domain containing 1
chr12_+_88953399 0.705 ENSMUST00000057634.7
Nrxn3
neurexin III
chr1_+_153749496 0.698 ENSMUST00000182722.1
Rnasel
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
chr2_-_102400863 0.692 ENSMUST00000102573.1
Trim44
tripartite motif-containing 44
chr4_-_140648736 0.682 ENSMUST00000039204.3
ENSMUST00000105799.1
ENSMUST00000097820.2
Arhgef10l


Rho guanine nucleotide exchange factor (GEF) 10-like


chr9_-_116175318 0.674 ENSMUST00000061101.4
ENSMUST00000035014.6
Tgfbr2

transforming growth factor, beta receptor II

chr1_+_87326997 0.668 ENSMUST00000027475.8
Gigyf2
GRB10 interacting GYF protein 2
chr11_-_116024489 0.653 ENSMUST00000016703.7
H3f3b
H3 histone, family 3B
chr1_-_132390301 0.649 ENSMUST00000132435.1
Tmcc2
transmembrane and coiled-coil domains 2
chr11_+_87592145 0.634 ENSMUST00000103179.3
ENSMUST00000092802.5
ENSMUST00000146871.1
Mtmr4


myotubularin related protein 4


chr5_-_107875035 0.631 ENSMUST00000138111.1
ENSMUST00000112642.1
Evi5

ecotropic viral integration site 5

chr13_-_113663670 0.628 ENSMUST00000054650.4
Hspb3
heat shock protein 3
chr2_-_25461021 0.623 ENSMUST00000151239.1
BC029214
cDNA sequence BC029214
chr19_+_8929628 0.613 ENSMUST00000096241.4
Eml3
echinoderm microtubule associated protein like 3
chr10_+_86779000 0.611 ENSMUST00000099396.2
Nt5dc3
5'-nucleotidase domain containing 3
chr16_-_4880284 0.608 ENSMUST00000037843.6
Ubald1
UBA-like domain containing 1
chr6_-_56901870 0.603 ENSMUST00000101367.2
Nt5c3
5'-nucleotidase, cytosolic III
chr12_+_31265279 0.596 ENSMUST00000002979.8
ENSMUST00000170495.1
Lamb1

laminin B1

chr9_-_109059711 0.591 ENSMUST00000061973.4
Trex1
three prime repair exonuclease 1
chr19_+_8664005 0.590 ENSMUST00000035444.3
ENSMUST00000163785.1
Chrm1

cholinergic receptor, muscarinic 1, CNS

chr1_+_75546258 0.588 ENSMUST00000124341.1
Slc4a3
solute carrier family 4 (anion exchanger), member 3
chr5_-_62766153 0.571 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr2_+_3424123 0.570 ENSMUST00000061852.5
ENSMUST00000100463.3
ENSMUST00000102988.3
ENSMUST00000115066.1
Dclre1c



DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae)



chr10_+_119992962 0.564 ENSMUST00000154238.1
Grip1
glutamate receptor interacting protein 1
chr3_+_79885930 0.563 ENSMUST00000029567.8
Fam198b
family with sequence similarity 198, member B
chr11_+_116030304 0.559 ENSMUST00000021116.5
ENSMUST00000106452.1
Unk

unkempt homolog (Drosophila)

chrX_+_74424534 0.535 ENSMUST00000135165.1
ENSMUST00000114128.1
ENSMUST00000114133.2
ENSMUST00000004330.3
Ikbkg



inhibitor of kappaB kinase gamma



chr6_+_17463826 0.533 ENSMUST00000140070.1
Met
met proto-oncogene
chr3_-_121283096 0.530 ENSMUST00000135818.1
ENSMUST00000137234.1
Tmem56

transmembrane protein 56

chr7_+_19181159 0.527 ENSMUST00000120595.1
ENSMUST00000048502.8
Eml2

echinoderm microtubule associated protein like 2

chr5_+_105732063 0.526 ENSMUST00000154807.1
Lrrc8d
leucine rich repeat containing 8D
chr14_+_62837679 0.526 ENSMUST00000014691.8
Wdfy2
WD repeat and FYVE domain containing 2
chr12_+_111166485 0.525 ENSMUST00000139162.1
Traf3
TNF receptor-associated factor 3
chr4_-_149126688 0.514 ENSMUST00000030815.2
Cort
cortistatin
chr17_-_47834682 0.509 ENSMUST00000066368.6
Mdfi
MyoD family inhibitor
chr18_+_40258361 0.504 ENSMUST00000091927.4
Kctd16
potassium channel tetramerisation domain containing 16
chr6_+_17693965 0.488 ENSMUST00000115419.1
St7
suppression of tumorigenicity 7
chr7_+_141468776 0.486 ENSMUST00000058746.5
Cd151
CD151 antigen
chr13_+_93303757 0.482 ENSMUST00000109494.1
Homer1
homer homolog 1 (Drosophila)
chr6_+_17693905 0.475 ENSMUST00000115420.1
St7
suppression of tumorigenicity 7
chr1_+_153749414 0.474 ENSMUST00000086209.3
Rnasel
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
chr3_+_103576081 0.465 ENSMUST00000183637.1
ENSMUST00000117221.2
ENSMUST00000118117.1
ENSMUST00000118563.2
Syt6



synaptotagmin VI



chr6_+_17694005 0.465 ENSMUST00000081635.6
ENSMUST00000052113.5
St7

suppression of tumorigenicity 7

chr4_+_42158092 0.464 ENSMUST00000098122.2
Gm13306
predicted gene 13306
chr1_+_134560190 0.462 ENSMUST00000112198.1
ENSMUST00000112197.1
Kdm5b

lysine (K)-specific demethylase 5B

chr6_+_17694167 0.462 ENSMUST00000115418.1
St7
suppression of tumorigenicity 7
chr9_-_109059216 0.461 ENSMUST00000112053.1
Trex1
three prime repair exonuclease 1
chr2_-_76215363 0.449 ENSMUST00000144892.1
Pde11a
phosphodiesterase 11A
chr8_+_120488416 0.446 ENSMUST00000034279.9
Gse1
genetic suppressor element 1
chr17_-_45592485 0.444 ENSMUST00000166119.1
Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr15_-_3979432 0.444 ENSMUST00000022791.8
Fbxo4
F-box protein 4
chrX_+_74424632 0.441 ENSMUST00000114129.2
ENSMUST00000132749.1
Ikbkg

inhibitor of kappaB kinase gamma

chr11_-_120467414 0.440 ENSMUST00000076921.6
Arl16
ADP-ribosylation factor-like 16
chr10_+_127290774 0.437 ENSMUST00000026475.8
ENSMUST00000139091.1
Ddit3

DNA-damage inducible transcript 3

chr7_-_80403315 0.434 ENSMUST00000147150.1
Furin
furin (paired basic amino acid cleaving enzyme)
chr10_+_116143881 0.429 ENSMUST00000105271.2
Ptprr
protein tyrosine phosphatase, receptor type, R
chr7_-_30195046 0.428 ENSMUST00000001845.5
Capns1
calpain, small subunit 1
chr13_+_93304799 0.421 ENSMUST00000080127.5
Homer1
homer homolog 1 (Drosophila)
chr10_+_21993890 0.411 ENSMUST00000092673.4
Sgk1
serum/glucocorticoid regulated kinase 1
chr10_+_60277627 0.409 ENSMUST00000105465.1
ENSMUST00000177779.1
ENSMUST00000179238.1
ENSMUST00000004316.8
Psap



prosaposin



chr8_+_4226827 0.408 ENSMUST00000053035.6
Lrrc8e
leucine rich repeat containing 8 family, member E
chr2_-_30124454 0.408 ENSMUST00000044751.8
Zer1
zyg-11 related, cell cycle regulator
chr19_-_32210969 0.401 ENSMUST00000151289.1
Sgms1
sphingomyelin synthase 1
chr5_+_105731755 0.396 ENSMUST00000127686.1
Lrrc8d
leucine rich repeat containing 8D
chr2_-_93849679 0.390 ENSMUST00000068513.4
ENSMUST00000041593.8
ENSMUST00000130077.1
Accs


1-aminocyclopropane-1-carboxylate synthase (non-functional)


chr4_-_91376433 0.388 ENSMUST00000107109.2
ENSMUST00000107111.2
ENSMUST00000107120.1
Elavl2


ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)


chr10_+_128411616 0.385 ENSMUST00000096386.5
ENSMUST00000171342.1
Rnf41

ring finger protein 41

chr15_-_97767798 0.383 ENSMUST00000129223.2
ENSMUST00000126854.2
ENSMUST00000135080.1
Rapgef3


Rap guanine nucleotide exchange factor (GEF) 3



Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 5.9 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.9 6.5 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.9 3.6 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.8 4.6 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.7 4.4 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.7 2.0 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.6 3.0 GO:1905169 protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171)
0.5 2.8 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.4 2.1 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.4 2.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.4 1.7 GO:0035624 receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.4 1.2 GO:0035441 cell migration involved in vasculogenesis(GO:0035441) metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
0.3 1.0 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.3 2.6 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.3 1.0 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.3 1.9 GO:0007021 tubulin complex assembly(GO:0007021)
0.3 1.0 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.3 0.3 GO:0030862 positive regulation of polarized epithelial cell differentiation(GO:0030862)
0.3 1.6 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.3 1.8 GO:0046103 ADP biosynthetic process(GO:0006172) inosine biosynthetic process(GO:0046103)
0.3 1.2 GO:0090472 dibasic protein processing(GO:0090472)
0.3 2.9 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.3 0.9 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.3 1.9 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.3 4.0 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.2 0.7 GO:0051464 positive regulation of cortisol secretion(GO:0051464)
0.2 0.7 GO:0086047 membrane depolarization during Purkinje myocyte cell action potential(GO:0086047)
0.2 1.9 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.2 1.1 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.2 0.9 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.2 1.9 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.2 3.0 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.2 2.3 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.2 2.3 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.2 1.3 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.2 1.3 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.2 1.2 GO:0015862 uridine transport(GO:0015862)
0.2 0.7 GO:1902340 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.2 6.4 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.2 2.2 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.2 0.5 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.1 0.4 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.1 1.4 GO:0030049 muscle filament sliding(GO:0030049)
0.1 0.4 GO:0071544 diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.1 0.3 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
0.1 0.8 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.1 0.6 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.1 0.6 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 0.8 GO:0007296 vitellogenesis(GO:0007296)
0.1 3.1 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.1 1.1 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 0.4 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 1.2 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.1 3.2 GO:0071625 vocalization behavior(GO:0071625)
0.1 0.1 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
0.1 1.2 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 1.0 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 2.0 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 0.6 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 4.2 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 0.4 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.1 0.5 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.1 0.4 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.1 1.8 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 0.3 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.1 6.0 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.1 0.3 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.1 1.5 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 0.6 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 0.3 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.1 2.3 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 0.6 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.1 GO:0030397 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.1 0.4 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.1 0.3 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 2.5 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 0.7 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.1 0.3 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 0.2 GO:0035937 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.1 0.1 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.1 0.6 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 0.8 GO:0006622 protein targeting to lysosome(GO:0006622) regulation of exosomal secretion(GO:1903541) positive regulation of exosomal secretion(GO:1903543)
0.0 1.1 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.7 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 2.1 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.0 0.2 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.1 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.3 GO:0019532 oxalate transport(GO:0019532)
0.0 1.5 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.3 GO:0015074 DNA integration(GO:0015074)
0.0 0.6 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 1.7 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 1.1 GO:0072337 modified amino acid transport(GO:0072337)
0.0 0.1 GO:0045713 low-density lipoprotein particle receptor biosynthetic process(GO:0045713) regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714)
0.0 2.6 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 0.8 GO:0033198 response to ATP(GO:0033198)
0.0 0.8 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.0 0.7 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 3.3 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.3 GO:0044804 nucleophagy(GO:0044804)
0.0 1.0 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.4 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.2 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0 1.5 GO:0045806 negative regulation of endocytosis(GO:0045806)
0.0 1.0 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 0.5 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.2 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.4 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.2 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.0 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.2 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.0 0.2 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.0 0.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 2.1 GO:0030641 regulation of cellular pH(GO:0030641)
0.0 0.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.2 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.2 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.3 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 1.7 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.3 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313) negative regulation of neutrophil activation(GO:1902564)
0.0 0.6 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 0.3 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.3 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.2 GO:0032060 bleb assembly(GO:0032060)
0.0 0.3 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.8 GO:0051438 regulation of ubiquitin-protein transferase activity(GO:0051438)
0.0 0.1 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.0 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 2.0 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.4 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.2 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.1 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.4 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.2 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.1 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.1 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 5.9 GO:0005638 lamin filament(GO:0005638)
0.7 2.9 GO:0099569 presynaptic cytoskeleton(GO:0099569)
0.7 4.6 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.6 1.9 GO:0005927 muscle tendon junction(GO:0005927)
0.4 4.9 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.4 1.7 GO:0031673 H zone(GO:0031673)
0.4 2.4 GO:0097513 myosin II filament(GO:0097513)
0.4 1.1 GO:0044753 amphisome(GO:0044753)
0.3 1.4 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.3 3.0 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.3 1.9 GO:0097512 cardiac myofibril(GO:0097512)
0.2 1.2 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.2 1.8 GO:0001520 outer dense fiber(GO:0001520)
0.2 0.9 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.2 3.1 GO:1990635 proximal dendrite(GO:1990635)
0.2 1.1 GO:0071439 clathrin complex(GO:0071439)
0.2 2.6 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.4 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.1 1.5 GO:0016461 unconventional myosin complex(GO:0016461)
0.1 2.6 GO:0032279 asymmetric synapse(GO:0032279)
0.1 0.3 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1 6.5 GO:0009925 basal plasma membrane(GO:0009925)
0.1 1.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 0.3 GO:0097447 dendritic tree(GO:0097447)
0.1 0.3 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.1 3.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 3.1 GO:0048786 presynaptic active zone(GO:0048786)
0.1 1.0 GO:0042581 specific granule(GO:0042581)
0.1 2.6 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 10.2 GO:0001650 fibrillar center(GO:0001650)
0.1 0.8 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 0.6 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 3.4 GO:0031985 Golgi cisterna(GO:0031985)
0.1 3.3 GO:0042734 presynaptic membrane(GO:0042734)
0.1 0.8 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 0.8 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.6 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 1.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 3.7 GO:0005604 basement membrane(GO:0005604)
0.0 8.2 GO:0016324 apical plasma membrane(GO:0016324)
0.0 5.0 GO:0055037 recycling endosome(GO:0055037)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 1.9 GO:0072562 blood microparticle(GO:0072562)
0.0 2.3 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.6 GO:0097440 apical dendrite(GO:0097440)
0.0 4.0 GO:0036464 cytoplasmic ribonucleoprotein granule(GO:0036464)
0.0 0.7 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.4 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.3 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)
0.0 1.2 GO:0045177 apical part of cell(GO:0045177)
0.0 1.7 GO:0043679 axon terminus(GO:0043679)
0.0 1.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 2.7 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.1 GO:0044754 secondary lysosome(GO:0005767) autolysosome(GO:0044754)
0.0 1.2 GO:0005769 early endosome(GO:0005769)
0.0 0.6 GO:0005844 polysome(GO:0005844)
0.0 0.7 GO:0030139 endocytic vesicle(GO:0030139)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.5 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.6 1.7 GO:0051379 epinephrine binding(GO:0051379)
0.4 2.6 GO:0005042 netrin receptor activity(GO:0005042)
0.4 4.9 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.4 4.3 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.3 3.0 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.3 4.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.3 1.0 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.3 2.0 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.3 1.1 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.3 1.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.3 1.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.2 1.0 GO:1903135 cupric ion binding(GO:1903135)
0.2 1.2 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.2 5.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 4.6 GO:0051787 misfolded protein binding(GO:0051787)
0.2 0.7 GO:0004966 galanin receptor activity(GO:0004966)
0.2 1.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 3.0 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.2 6.4 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 5.8 GO:0042805 actinin binding(GO:0042805)
0.2 3.4 GO:0017160 Ral GTPase binding(GO:0017160)
0.2 2.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.2 0.7 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.2 1.8 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.8 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.9 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.6 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 1.7 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.6 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 2.1 GO:0050811 GABA receptor binding(GO:0050811)
0.1 3.1 GO:0070064 proline-rich region binding(GO:0070064)
0.1 2.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 4.3 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.9 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 1.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.7 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 2.6 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 2.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.3 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 0.6 GO:1990715 mRNA CDS binding(GO:1990715)
0.1 0.4 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 1.9 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 1.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 2.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.3 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 1.1 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.4 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 0.6 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.1 0.6 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 0.3 GO:0004859 phospholipase inhibitor activity(GO:0004859) phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.4 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 4.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.3 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 1.8 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.2 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.1 4.2 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.1 0.2 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.4 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 1.1 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 1.9 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 1.1 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.3 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 1.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 1.2 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.7 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0003883 CTP synthase activity(GO:0003883)
0.0 2.0 GO:0005518 collagen binding(GO:0005518)
0.0 0.7 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 1.0 GO:0043236 laminin binding(GO:0043236)
0.0 0.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 8.2 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.3 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 1.6 GO:0017022 myosin binding(GO:0017022)
0.0 2.7 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 2.9 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.8 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.7 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 1.2 GO:0019843 rRNA binding(GO:0019843)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 4.9 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.1 GO:0005522 profilin binding(GO:0005522)
0.0 3.7 GO:0008017 microtubule binding(GO:0008017)
0.0 1.7 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.8 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 1.6 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.8 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 1.1 GO:0030165 PDZ domain binding(GO:0030165)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.0 PID_ARF6_PATHWAY Arf6 signaling events
0.1 4.2 PID_ARF_3PATHWAY Arf1 pathway
0.1 0.9 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.6 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 6.0 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 2.6 SIG_IL4RECEPTOR_IN_B_LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.1 4.4 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 1.2 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.1 1.1 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 3.0 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 1.6 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 5.0 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.1 1.6 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.1 1.7 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 2.5 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 0.8 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.1 1.6 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.1 1.5 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.1 3.2 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 0.7 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.0 1.7 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.6 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 1.2 PID_ATM_PATHWAY ATM pathway
0.0 0.7 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 0.6 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.0 1.9 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.8 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.9 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 0.2 PID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.4 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.0 1.1 PID_TNF_PATHWAY TNF receptor signaling pathway
0.0 0.7 PID_BCR_5PATHWAY BCR signaling pathway
0.0 0.9 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.3 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 2.2 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.2 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.8 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.0 0.2 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 0.6 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.7 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.1 PID_CXCR3_PATHWAY CXCR3-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.9 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.2 8.9 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.2 2.6 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 2.0 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.2 2.3 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.4 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 1.3 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 6.3 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 2.0 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.1 4.3 REACTOME_CA_DEPENDENT_EVENTS Genes involved in Ca-dependent events
0.1 1.1 REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 1.9 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 2.4 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.1 1.3 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.1 1.1 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 1.6 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 0.4 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.4 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.3 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 3.0 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.4 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.6 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.9 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.0 1.2 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.1 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.3 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 1.6 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.4 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.7 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.2 REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION Genes involved in Downstream signal transduction
0.0 1.8 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.7 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.4 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.5 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis