Motif ID: Rxrb

Z-value: 0.696


Transcription factors associated with Rxrb:

Gene SymbolEntrez IDGene Name
Rxrb ENSMUSG00000039656.10 Rxrb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rxrbmm10_v2_chr17_+_34032071_34032196-0.231.4e-01Click!


Activity profile for motif Rxrb.

activity profile for motif Rxrb


Sorted Z-values histogram for motif Rxrb

Sorted Z-values for motif Rxrb



Network of associatons between targets according to the STRING database.



First level regulatory network of Rxrb

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_118052235 6.144 ENSMUST00000022725.2
Dct
dopachrome tautomerase
chr10_+_93641041 4.197 ENSMUST00000020204.4
Ntn4
netrin 4
chr18_+_57142782 3.887 ENSMUST00000139892.1
Megf10
multiple EGF-like-domains 10
chr4_+_136143497 3.602 ENSMUST00000008016.2
Id3
inhibitor of DNA binding 3
chr4_-_117178726 3.380 ENSMUST00000153953.1
ENSMUST00000106436.1
Kif2c

kinesin family member 2C

chr6_-_23248264 3.330 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr10_-_88146867 2.817 ENSMUST00000164121.1
ENSMUST00000164803.1
ENSMUST00000168163.1
ENSMUST00000048518.9
Parpbp



PARP1 binding protein



chr1_+_84839833 2.663 ENSMUST00000097672.3
Fbxo36
F-box protein 36
chr1_+_146420434 2.656 ENSMUST00000163646.1
Gm5263
predicted gene 5263
chr12_+_91400990 2.486 ENSMUST00000021346.7
ENSMUST00000021343.6
Tshr

thyroid stimulating hormone receptor

chr4_+_44300876 2.442 ENSMUST00000045607.5
Melk
maternal embryonic leucine zipper kinase
chr11_+_40733936 2.349 ENSMUST00000127382.1
Nudcd2
NudC domain containing 2
chr5_+_110839973 2.236 ENSMUST00000066160.1
Chek2
checkpoint kinase 2
chr11_-_40733373 2.194 ENSMUST00000020579.8
Hmmr
hyaluronan mediated motility receptor (RHAMM)
chr11_+_40733639 2.035 ENSMUST00000020578.4
Nudcd2
NudC domain containing 2
chr1_+_6487231 1.972 ENSMUST00000140079.1
ENSMUST00000131494.1
St18

suppression of tumorigenicity 18

chr1_-_170306332 1.761 ENSMUST00000179801.1
Gm7694
predicted gene 7694
chr5_-_116422858 1.702 ENSMUST00000036991.4
Hspb8
heat shock protein 8
chr1_+_74791516 1.677 ENSMUST00000006718.8
Wnt10a
wingless related MMTV integration site 10a
chr10_+_88147061 1.659 ENSMUST00000169309.1
Nup37
nucleoporin 37
chr10_+_88146992 1.594 ENSMUST00000052355.7
Nup37
nucleoporin 37
chr1_+_131910458 1.383 ENSMUST00000062264.6
Nucks1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr15_-_78529617 1.359 ENSMUST00000023075.8
C1qtnf6
C1q and tumor necrosis factor related protein 6
chr6_+_113531675 1.266 ENSMUST00000036340.5
ENSMUST00000101051.2
Fancd2

Fanconi anemia, complementation group D2

chr17_-_32388885 1.259 ENSMUST00000087703.5
ENSMUST00000170603.1
Wiz

widely-interspaced zinc finger motifs

chr8_+_72135247 1.253 ENSMUST00000003575.9
Tpm4
tropomyosin 4
chr5_+_119834663 1.238 ENSMUST00000018407.6
Tbx5
T-box 5
chrX_-_23365044 1.211 ENSMUST00000115313.1
Klhl13
kelch-like 13
chr11_-_68973840 1.084 ENSMUST00000038644.4
Rangrf
RAN guanine nucleotide release factor
chr12_-_98737405 1.016 ENSMUST00000170188.1
Ptpn21
protein tyrosine phosphatase, non-receptor type 21
chr14_+_20929416 1.004 ENSMUST00000022369.7
Vcl
vinculin
chr4_+_130047840 1.002 ENSMUST00000044565.8
ENSMUST00000132251.1
Col16a1

collagen, type XVI, alpha 1

chr17_-_35704000 0.989 ENSMUST00000097333.3
ENSMUST00000003628.6
Ddr1

discoidin domain receptor family, member 1

chr5_+_137630116 0.977 ENSMUST00000175968.1
Lrch4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr2_+_121449362 0.973 ENSMUST00000110615.1
ENSMUST00000099475.5
Serf2

small EDRK-rich factor 2

chr14_-_118706180 0.962 ENSMUST00000036554.6
ENSMUST00000166646.1
Abcc4

ATP-binding cassette, sub-family C (CFTR/MRP), member 4

chr12_-_111713185 0.934 ENSMUST00000054636.6
Bag5
BCL2-associated athanogene 5
chr16_-_76403673 0.851 ENSMUST00000052867.7
Gm9843
predicted gene 9843
chr11_-_53430779 0.849 ENSMUST00000061326.4
ENSMUST00000109021.3
Uqcrq

ubiquinol-cytochrome c reductase, complex III subunit VII

chr5_-_134946917 0.835 ENSMUST00000051401.2
Cldn4
claudin 4
chr2_-_73911323 0.766 ENSMUST00000111996.1
ENSMUST00000018914.2
Atp5g3

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)

chr6_-_124965248 0.755 ENSMUST00000129976.1
Cops7a
COP9 (constitutive photomorphogenic) homolog, subunit 7a (Arabidopsis thaliana)
chr3_-_96172384 0.746 ENSMUST00000180958.1
Gm17690
predicted gene, 17690
chr19_-_6980420 0.720 ENSMUST00000070878.8
ENSMUST00000177752.1
Fkbp2

FK506 binding protein 2

chr4_+_130047914 0.676 ENSMUST00000142293.1
Col16a1
collagen, type XVI, alpha 1
chr3_+_96172327 0.660 ENSMUST00000076372.4
Sf3b4
splicing factor 3b, subunit 4
chr16_+_31663841 0.640 ENSMUST00000115201.1
Dlg1
discs, large homolog 1 (Drosophila)
chr12_-_111712909 0.632 ENSMUST00000160576.1
Bag5
BCL2-associated athanogene 5
chr12_+_111713255 0.631 ENSMUST00000040519.5
ENSMUST00000160366.1
ENSMUST00000163220.2
ENSMUST00000162316.1
Apopt1



apoptogenic, mitochondrial 1



chr12_-_40223149 0.630 ENSMUST00000171553.1
ENSMUST00000001672.5
Ifrd1

interferon-related developmental regulator 1

chr5_-_134747241 0.620 ENSMUST00000015138.9
Eln
elastin
chr16_+_31663935 0.617 ENSMUST00000100001.3
ENSMUST00000064477.7
Dlg1

discs, large homolog 1 (Drosophila)

chr6_+_120836201 0.609 ENSMUST00000009256.2
Bcl2l13
BCL2-like 13 (apoptosis facilitator)
chr1_+_86021935 0.605 ENSMUST00000052854.6
ENSMUST00000125083.1
ENSMUST00000152501.1
ENSMUST00000113344.1
ENSMUST00000130504.1
ENSMUST00000153247.2
Spata3





spermatogenesis associated 3





chr5_+_47984571 0.603 ENSMUST00000174313.1
Slit2
slit homolog 2 (Drosophila)
chr15_+_76797628 0.602 ENSMUST00000165535.2
Gm17271
predicted gene, 17271
chr10_-_53647080 0.593 ENSMUST00000169866.1
Fam184a
family with sequence similarity 184, member A
chr6_-_124965403 0.581 ENSMUST00000129446.1
ENSMUST00000032220.8
Cops7a

COP9 (constitutive photomorphogenic) homolog, subunit 7a (Arabidopsis thaliana)

chr6_-_124965485 0.571 ENSMUST00000112439.2
Cops7a
COP9 (constitutive photomorphogenic) homolog, subunit 7a (Arabidopsis thaliana)
chr14_+_54476100 0.533 ENSMUST00000164766.1
ENSMUST00000164697.1
Rem2

rad and gem related GTP binding protein 2

chr11_-_29547820 0.522 ENSMUST00000102844.3
Rps27a
ribosomal protein S27A
chr11_-_50325599 0.521 ENSMUST00000179865.1
ENSMUST00000020637.8
Canx

calnexin

chr18_+_60774510 0.509 ENSMUST00000025511.3
Rps14
ribosomal protein S14
chr6_-_88446491 0.489 ENSMUST00000165242.1
Eefsec
eukaryotic elongation factor, selenocysteine-tRNA-specific
chr12_+_108792946 0.487 ENSMUST00000021692.7
Yy1
YY1 transcription factor
chr6_-_124965207 0.473 ENSMUST00000148485.1
Cops7a
COP9 (constitutive photomorphogenic) homolog, subunit 7a (Arabidopsis thaliana)
chr5_+_3803160 0.470 ENSMUST00000171023.1
ENSMUST00000080085.4
Krit1

KRIT1, ankyrin repeat containing

chr15_-_79285502 0.450 ENSMUST00000165408.1
Baiap2l2
BAI1-associated protein 2-like 2
chr18_+_60774675 0.427 ENSMUST00000118551.1
Rps14
ribosomal protein S14
chr2_-_119477613 0.416 ENSMUST00000110808.1
ENSMUST00000049920.7
Ino80

INO80 homolog (S. cerevisiae)

chr10_-_128821576 0.415 ENSMUST00000026409.3
Ormdl2
ORM1-like 2 (S. cerevisiae)
chr19_+_11770415 0.394 ENSMUST00000167199.1
Mrpl16
mitochondrial ribosomal protein L16
chr4_+_57845240 0.392 ENSMUST00000102903.1
ENSMUST00000107598.3
Akap2

A kinase (PRKA) anchor protein 2

chr11_-_70255329 0.375 ENSMUST00000108574.2
ENSMUST00000000329.2
Alox12

arachidonate 12-lipoxygenase

chr19_-_4615453 0.372 ENSMUST00000053597.2
Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr12_-_111712946 0.365 ENSMUST00000160825.1
ENSMUST00000162953.1
Bag5

BCL2-associated athanogene 5

chr17_+_28177339 0.361 ENSMUST00000073534.2
ENSMUST00000002318.1
Zfp523

zinc finger protein 523

chr5_-_123666682 0.353 ENSMUST00000149410.1
Clip1
CAP-GLY domain containing linker protein 1
chr5_+_72914554 0.335 ENSMUST00000143829.1
Slain2
SLAIN motif family, member 2
chr12_-_113260217 0.320 ENSMUST00000178282.1
Igha
immunoglobulin heavy constant alpha
chr7_+_28440927 0.309 ENSMUST00000078845.6
Gmfg
glia maturation factor, gamma
chr10_+_80148263 0.305 ENSMUST00000099492.3
ENSMUST00000042057.5
Midn

midnolin

chr15_-_82354280 0.294 ENSMUST00000023085.5
Ndufa6
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6 (B14)
chr2_+_158794807 0.287 ENSMUST00000029186.7
ENSMUST00000109478.2
ENSMUST00000156893.1
Dhx35


DEAH (Asp-Glu-Ala-His) box polypeptide 35


chr3_+_122729158 0.279 ENSMUST00000066728.5
Pde5a
phosphodiesterase 5A, cGMP-specific
chr5_+_72914264 0.248 ENSMUST00000144843.1
Slain2
SLAIN motif family, member 2
chr1_+_160044564 0.246 ENSMUST00000168359.1
4930523C07Rik
RIKEN cDNA 4930523C07 gene
chr7_-_86775860 0.233 ENSMUST00000001824.5
Folh1
folate hydrolase 1
chr11_-_23519181 0.231 ENSMUST00000020527.5
1700093K21Rik
RIKEN cDNA 1700093K21 gene
chr11_-_97629685 0.229 ENSMUST00000052281.4
E130012A19Rik
RIKEN cDNA E130012A19 gene
chr7_+_102229999 0.224 ENSMUST00000120119.1
Pgap2
post-GPI attachment to proteins 2
chr11_+_97315716 0.213 ENSMUST00000019026.3
ENSMUST00000132168.1
Mrpl45

mitochondrial ribosomal protein L45

chr4_-_58912678 0.210 ENSMUST00000144512.1
ENSMUST00000102889.3
ENSMUST00000055822.8
AI314180


expressed sequence AI314180


chr2_-_119662756 0.201 ENSMUST00000028768.1
ENSMUST00000110801.1
ENSMUST00000110802.1
Ndufaf1


NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1


chr1_+_160044374 0.199 ENSMUST00000163892.1
4930523C07Rik
RIKEN cDNA 4930523C07 gene
chr5_+_121795034 0.195 ENSMUST00000162327.1
Atxn2
ataxin 2
chr11_-_97699634 0.192 ENSMUST00000103148.1
ENSMUST00000169807.1
Pcgf2

polycomb group ring finger 2

chr7_-_4778141 0.167 ENSMUST00000094892.5
Il11
interleukin 11
chr6_-_83054415 0.151 ENSMUST00000113962.1
ENSMUST00000089645.6
ENSMUST00000113963.1
Htra2


HtrA serine peptidase 2


chr16_-_30388530 0.144 ENSMUST00000100013.2
ENSMUST00000061350.6
Atp13a3

ATPase type 13A3

chr13_+_5861489 0.137 ENSMUST00000000080.6
Klf6
Kruppel-like factor 6
chr10_-_128547722 0.133 ENSMUST00000040572.3
Zc3h10
zinc finger CCCH type containing 10
chr2_+_151542483 0.129 ENSMUST00000044011.5
Fkbp1a
FK506 binding protein 1a
chr3_-_94786430 0.111 ENSMUST00000107272.1
Cgn
cingulin
chrX_+_99042581 0.094 ENSMUST00000036606.7
Stard8
START domain containing 8
chr17_-_27820445 0.088 ENSMUST00000114859.1
D17Wsu92e
DNA segment, Chr 17, Wayne State University 92, expressed
chr3_+_90062781 0.053 ENSMUST00000029551.2
1700094D03Rik
RIKEN cDNA 1700094D03 gene
chr7_+_35802593 0.052 ENSMUST00000052454.2
E130304I02Rik
RIKEN cDNA E130304I02 gene
chr6_+_29396576 0.052 ENSMUST00000115275.1
Ccdc136
coiled-coil domain containing 136
chr18_-_80713062 0.051 ENSMUST00000170905.1
ENSMUST00000078049.4
Nfatc1

nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1

chr9_-_106891870 0.050 ENSMUST00000160503.1
ENSMUST00000159620.2
ENSMUST00000160978.1
Manf


mesencephalic astrocyte-derived neurotrophic factor


chr10_+_81136223 0.042 ENSMUST00000048128.8
Zbtb7a
zinc finger and BTB domain containing 7a
chr14_-_16243309 0.036 ENSMUST00000112625.1
Oxsm
3-oxoacyl-ACP synthase, mitochondrial
chr7_-_31055594 0.031 ENSMUST00000039909.6
Fxyd1
FXYD domain-containing ion transport regulator 1
chr7_+_138846335 0.022 ENSMUST00000041097.6
Ppp2r2d
protein phosphatase 2, regulatory subunit B, delta isoform
chr9_-_50659780 0.022 ENSMUST00000034567.3
Dlat
dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)
chr9_+_55208925 0.017 ENSMUST00000034859.8
Fbxo22
F-box protein 22

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 6.1 GO:0006570 tyrosine metabolic process(GO:0006570)
0.8 4.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.7 3.4 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.6 3.9 GO:0043654 skeletal muscle satellite cell activation(GO:0014719) recognition of apoptotic cell(GO:0043654)
0.6 2.2 GO:1903463 regulation of mitotic cell cycle DNA replication(GO:1903463)
0.6 3.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.5 1.4 GO:0019046 release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382)
0.4 2.5 GO:1904587 response to glycoprotein(GO:1904587)
0.3 1.3 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905024)
0.2 1.2 GO:0051890 regulation of cardioblast differentiation(GO:0051890)
0.2 1.9 GO:0061084 negative regulation of protein refolding(GO:0061084)
0.2 1.7 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.2 0.6 GO:0021972 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.2 2.8 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.2 1.3 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.2 1.1 GO:0086028 bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
0.2 2.1 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.2 0.5 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.2 1.7 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.1 0.8 GO:0021539 subthalamus development(GO:0021539)
0.1 2.4 GO:0000338 protein deneddylation(GO:0000338)
0.1 0.4 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
0.1 3.6 GO:0030903 notochord development(GO:0030903)
0.1 1.0 GO:0006855 drug transmembrane transport(GO:0006855)
0.1 0.4 GO:0019372 lipoxygenase pathway(GO:0019372)
0.1 0.3 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678)
0.1 0.6 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.1 0.4 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 1.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 1.0 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 1.7 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.1 0.8 GO:0061436 establishment of skin barrier(GO:0061436)
0.1 1.4 GO:0070208 protein heterotrimerization(GO:0070208)
0.1 0.5 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 1.0 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.1 0.5 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.1 0.3 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 2.4 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.0 0.3 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.9 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.6 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.0 0.8 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.5 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.7 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.5 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 3.3 GO:0051028 mRNA transport(GO:0051028)
0.0 0.3 GO:0002385 mucosal immune response(GO:0002385)
0.0 0.6 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.0 1.4 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.1 GO:0060854 patterning of lymph vessels(GO:0060854)
0.0 1.8 GO:0006457 protein folding(GO:0006457)
0.0 0.1 GO:0002014 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.2 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0031088 platelet dense granule membrane(GO:0031088)
0.3 3.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.2 6.1 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.2 0.6 GO:0071953 elastic fiber(GO:0071953)
0.2 1.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.2 3.9 GO:0001891 phagocytic cup(GO:0001891)
0.1 4.3 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.4 GO:0035339 SPOTS complex(GO:0035339)
0.1 1.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 1.0 GO:0005916 fascia adherens(GO:0005916)
0.1 0.8 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 0.5 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 0.9 GO:0031011 Ino80 complex(GO:0031011)
0.1 0.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 3.9 GO:0005604 basement membrane(GO:0005604)
0.0 0.5 GO:0071439 clathrin complex(GO:0071439)
0.0 3.0 GO:0005581 collagen trimer(GO:0005581)
0.0 0.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 4.4 GO:0000776 kinetochore(GO:0000776)
0.0 1.3 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 1.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 2.7 GO:0016605 PML body(GO:0016605)
0.0 0.7 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 1.9 GO:0016234 inclusion body(GO:0016234)
0.0 1.1 GO:0014704 intercalated disc(GO:0014704)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 2.7 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.3 GO:0000793 condensed chromosome(GO:0000793)
0.0 2.0 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 3.6 GO:0043235 receptor complex(GO:0043235)
0.0 0.2 GO:0005771 multivesicular body(GO:0005771)
0.0 0.6 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.9 GO:0001849 complement component C1q binding(GO:0001849)
0.5 4.8 GO:0043237 laminin-1 binding(GO:0043237)
0.5 6.1 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.2 3.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 1.3 GO:0097016 L27 domain binding(GO:0097016)
0.2 2.5 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 2.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.0 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.8 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 1.0 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.9 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 3.6 GO:0005504 fatty acid binding(GO:0005504)
0.1 0.5 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 1.0 GO:0015238 drug transmembrane transporter activity(GO:0015238)
0.0 2.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.8 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.8 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 1.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 1.7 GO:0005109 frizzled binding(GO:0005109)
0.0 3.8 GO:0051082 unfolded protein binding(GO:0051082)
0.0 1.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.4 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 1.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.5 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 1.6 GO:0051087 chaperone binding(GO:0051087)
0.0 3.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.1 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 1.7 GO:0005178 integrin binding(GO:0005178)
0.0 0.2 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 1.4 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.1 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.2 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.1 4.6 PID_AURORA_B_PATHWAY Aurora B signaling
0.1 3.5 PID_ATM_PATHWAY ATM pathway
0.1 2.5 PID_ARF6_PATHWAY Arf6 signaling events
0.1 1.7 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.6 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 2.0 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.0 5.5 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 1.3 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.1 PID_ALK2_PATHWAY ALK2 signaling events
0.0 1.4 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
0.3 1.8 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.2 2.2 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.2 2.2 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 3.4 REACTOME_KINESINS Genes involved in Kinesins
0.1 3.3 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.1 4.8 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.1 1.3 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 2.3 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.5 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.9 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.7 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.8 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 1.7 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.9 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.1 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 0.2 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.7 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 1.0 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+