Motif ID: Runx2_Bcl11a
Z-value: 1.148


Transcription factors associated with Runx2_Bcl11a:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Bcl11a | ENSMUSG00000000861.9 | Bcl11a |
Runx2 | ENSMUSG00000039153.10 | Runx2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Bcl11a | mm10_v2_chr11_+_24078022_24078076 | 0.10 | 5.2e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.9 | 5.6 | GO:0046110 | xanthine metabolic process(GO:0046110) |
1.2 | 3.6 | GO:0038095 | positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095) |
1.2 | 13.0 | GO:0042572 | retinol metabolic process(GO:0042572) |
1.0 | 7.3 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
1.0 | 3.0 | GO:0050975 | sensory perception of touch(GO:0050975) |
0.9 | 2.7 | GO:1903279 | regulation of calcium:sodium antiporter activity(GO:1903279) |
0.9 | 7.7 | GO:0002903 | negative regulation of B cell apoptotic process(GO:0002903) |
0.7 | 2.1 | GO:0050703 | interleukin-1 alpha secretion(GO:0050703) |
0.7 | 2.0 | GO:0021837 | motogenic signaling involved in postnatal olfactory bulb interneuron migration(GO:0021837) positive regulation of mitotic cell cycle DNA replication(GO:1903465) |
0.7 | 2.0 | GO:1904959 | elastin biosynthetic process(GO:0051542) copper ion export(GO:0060003) regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959) |
0.6 | 3.9 | GO:0045919 | positive regulation of cytolysis(GO:0045919) |
0.6 | 4.5 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
0.6 | 1.9 | GO:2000297 | negative regulation of synapse maturation(GO:2000297) |
0.6 | 3.1 | GO:0015671 | oxygen transport(GO:0015671) |
0.6 | 1.8 | GO:0048687 | positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) |
0.6 | 1.7 | GO:1904139 | microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) |
0.6 | 3.3 | GO:0097646 | calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647) |
0.6 | 1.1 | GO:0060769 | positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769) |
0.5 | 2.1 | GO:0021564 | glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564) |
0.5 | 2.6 | GO:0019852 | L-ascorbic acid metabolic process(GO:0019852) |
0.5 | 2.6 | GO:0010519 | negative regulation of phospholipase activity(GO:0010519) |
0.5 | 1.6 | GO:0014738 | regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900) |
0.5 | 4.0 | GO:0098707 | positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707) |
0.4 | 2.1 | GO:2000255 | negative regulation of male germ cell proliferation(GO:2000255) |
0.4 | 1.2 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
0.4 | 2.6 | GO:0015862 | uridine transport(GO:0015862) |
0.4 | 1.4 | GO:1900220 | semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220) |
0.3 | 1.0 | GO:0016115 | terpenoid catabolic process(GO:0016115) |
0.3 | 1.0 | GO:0051342 | regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344) |
0.3 | 1.3 | GO:0071475 | cellular hyperosmotic salinity response(GO:0071475) |
0.3 | 0.9 | GO:0019046 | release from viral latency(GO:0019046) |
0.3 | 0.9 | GO:0042939 | glutathione transport(GO:0034635) oligopeptide transmembrane transport(GO:0035672) xenobiotic transport(GO:0042908) tripeptide transport(GO:0042939) |
0.3 | 1.5 | GO:0060414 | aorta smooth muscle tissue morphogenesis(GO:0060414) |
0.3 | 0.9 | GO:0006550 | isoleucine catabolic process(GO:0006550) |
0.3 | 0.8 | GO:1905051 | regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053) |
0.3 | 1.9 | GO:0045650 | negative regulation of macrophage differentiation(GO:0045650) |
0.3 | 0.8 | GO:0046340 | diacylglycerol catabolic process(GO:0046340) |
0.3 | 1.4 | GO:1904721 | regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721) |
0.3 | 0.8 | GO:0033364 | mast cell secretory granule organization(GO:0033364) |
0.3 | 1.3 | GO:0051182 | coenzyme transport(GO:0051182) |
0.3 | 0.8 | GO:0045347 | negative regulation of MHC class II biosynthetic process(GO:0045347) |
0.3 | 1.0 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
0.2 | 0.7 | GO:2000016 | negative regulation of determination of dorsal identity(GO:2000016) |
0.2 | 0.2 | GO:0043401 | steroid hormone mediated signaling pathway(GO:0043401) |
0.2 | 0.7 | GO:0007621 | negative regulation of female receptivity(GO:0007621) |
0.2 | 0.7 | GO:0043379 | rRNA export from nucleus(GO:0006407) memory T cell differentiation(GO:0043379) response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) |
0.2 | 0.2 | GO:0038163 | thrombopoietin-mediated signaling pathway(GO:0038163) |
0.2 | 2.4 | GO:0051923 | sulfation(GO:0051923) |
0.2 | 1.5 | GO:0061718 | NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718) |
0.2 | 0.8 | GO:0060448 | dichotomous subdivision of terminal units involved in lung branching(GO:0060448) |
0.2 | 1.7 | GO:0036444 | calcium ion transmembrane import into mitochondrion(GO:0036444) |
0.2 | 0.8 | GO:0090472 | dibasic protein processing(GO:0090472) |
0.2 | 0.4 | GO:0097475 | motor neuron migration(GO:0097475) |
0.2 | 1.2 | GO:0072513 | positive regulation of secondary heart field cardioblast proliferation(GO:0072513) |
0.2 | 1.0 | GO:0038032 | termination of G-protein coupled receptor signaling pathway(GO:0038032) |
0.2 | 0.8 | GO:0070317 | negative regulation of G0 to G1 transition(GO:0070317) |
0.2 | 5.1 | GO:0032967 | positive regulation of collagen biosynthetic process(GO:0032967) |
0.2 | 0.8 | GO:0035937 | androgen catabolic process(GO:0006710) estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864) |
0.2 | 0.9 | GO:0007256 | activation of JNKK activity(GO:0007256) |
0.2 | 3.0 | GO:0043011 | myeloid dendritic cell differentiation(GO:0043011) |
0.2 | 2.1 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) |
0.2 | 0.5 | GO:0018103 | protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406) |
0.2 | 0.7 | GO:0071596 | ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596) |
0.2 | 2.0 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
0.2 | 1.2 | GO:2000258 | negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258) |
0.2 | 0.5 | GO:0035526 | retrograde transport, plasma membrane to Golgi(GO:0035526) |
0.2 | 0.5 | GO:2000170 | positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170) |
0.2 | 7.0 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
0.2 | 0.5 | GO:0090071 | negative regulation of ribosome biogenesis(GO:0090071) |
0.2 | 0.5 | GO:0072378 | blood coagulation, fibrin clot formation(GO:0072378) |
0.2 | 1.0 | GO:1903071 | positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071) |
0.2 | 0.8 | GO:0034638 | phosphatidylcholine catabolic process(GO:0034638) |
0.2 | 0.5 | GO:0002842 | T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) positive regulation of T cell mediated immune response to tumor cell(GO:0002842) positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) |
0.2 | 1.1 | GO:0014819 | regulation of skeletal muscle contraction(GO:0014819) |
0.2 | 1.1 | GO:0010968 | regulation of microtubule nucleation(GO:0010968) |
0.2 | 0.8 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
0.1 | 0.7 | GO:0032497 | detection of lipopolysaccharide(GO:0032497) |
0.1 | 0.6 | GO:0019355 | nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628) |
0.1 | 0.6 | GO:0035811 | negative regulation of urine volume(GO:0035811) |
0.1 | 1.0 | GO:0070886 | positive regulation of calcineurin-NFAT signaling cascade(GO:0070886) |
0.1 | 0.5 | GO:0072362 | regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362) |
0.1 | 0.4 | GO:0017055 | negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055) |
0.1 | 0.4 | GO:0010579 | regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579) |
0.1 | 1.5 | GO:1901841 | regulation of high voltage-gated calcium channel activity(GO:1901841) |
0.1 | 0.5 | GO:1904048 | negative regulation of synaptic vesicle recycling(GO:1903422) regulation of spontaneous neurotransmitter secretion(GO:1904048) |
0.1 | 1.0 | GO:1901387 | positive regulation of voltage-gated calcium channel activity(GO:1901387) |
0.1 | 0.7 | GO:0060665 | regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665) |
0.1 | 1.3 | GO:2000766 | negative regulation of cytoplasmic translation(GO:2000766) |
0.1 | 1.9 | GO:0015701 | bicarbonate transport(GO:0015701) |
0.1 | 0.7 | GO:0044375 | regulation of peroxisome size(GO:0044375) |
0.1 | 1.8 | GO:0006767 | water-soluble vitamin metabolic process(GO:0006767) |
0.1 | 0.2 | GO:0010726 | positive regulation of hydrogen peroxide metabolic process(GO:0010726) |
0.1 | 0.5 | GO:0070627 | vanadium ion transport(GO:0015676) lead ion transport(GO:0015692) ferrous iron import(GO:0070627) |
0.1 | 0.3 | GO:0033689 | negative regulation of osteoblast proliferation(GO:0033689) |
0.1 | 0.3 | GO:0036092 | phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092) |
0.1 | 0.7 | GO:0030263 | apoptotic chromosome condensation(GO:0030263) |
0.1 | 0.8 | GO:0033564 | anterior/posterior axon guidance(GO:0033564) |
0.1 | 0.9 | GO:0043615 | astrocyte cell migration(GO:0043615) |
0.1 | 0.3 | GO:1902396 | protein localization to bicellular tight junction(GO:1902396) |
0.1 | 0.1 | GO:0035482 | gastric motility(GO:0035482) gastric emptying(GO:0035483) |
0.1 | 0.5 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
0.1 | 0.9 | GO:0000042 | protein targeting to Golgi(GO:0000042) |
0.1 | 0.5 | GO:0042636 | negative regulation of hair cycle(GO:0042636) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279) |
0.1 | 0.6 | GO:2000310 | regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310) |
0.1 | 0.2 | GO:1904020 | regulation of G-protein coupled receptor internalization(GO:1904020) |
0.1 | 1.3 | GO:2000096 | positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
0.1 | 3.9 | GO:0045744 | negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744) |
0.1 | 0.4 | GO:0015669 | gas transport(GO:0015669) carbon dioxide transport(GO:0015670) |
0.1 | 0.7 | GO:0061042 | vascular wound healing(GO:0061042) |
0.1 | 1.7 | GO:0010592 | positive regulation of lamellipodium assembly(GO:0010592) |
0.1 | 1.2 | GO:1902170 | cellular response to reactive nitrogen species(GO:1902170) |
0.1 | 0.7 | GO:0045541 | negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206) |
0.1 | 0.7 | GO:0090074 | negative regulation of protein homodimerization activity(GO:0090074) |
0.1 | 0.7 | GO:0033184 | positive regulation of histone ubiquitination(GO:0033184) |
0.1 | 0.5 | GO:0032811 | negative regulation of epinephrine secretion(GO:0032811) |
0.1 | 0.9 | GO:0060575 | intestinal epithelial cell differentiation(GO:0060575) |
0.1 | 0.4 | GO:0051503 | adenine nucleotide transport(GO:0051503) |
0.1 | 0.9 | GO:0071670 | smooth muscle cell chemotaxis(GO:0071670) |
0.1 | 0.4 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
0.1 | 0.8 | GO:0014067 | negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067) |
0.1 | 1.3 | GO:0046069 | cGMP catabolic process(GO:0046069) |
0.1 | 0.3 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
0.1 | 0.4 | GO:1903690 | negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
0.1 | 0.2 | GO:0098501 | polynucleotide dephosphorylation(GO:0098501) |
0.1 | 0.2 | GO:1902915 | negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915) |
0.1 | 4.3 | GO:0038083 | peptidyl-tyrosine autophosphorylation(GO:0038083) |
0.1 | 0.5 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
0.1 | 1.3 | GO:0032957 | inositol trisphosphate metabolic process(GO:0032957) |
0.1 | 0.4 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
0.1 | 1.9 | GO:0030325 | adrenal gland development(GO:0030325) |
0.1 | 0.9 | GO:0008209 | androgen metabolic process(GO:0008209) |
0.1 | 0.3 | GO:0006447 | regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994) |
0.1 | 4.3 | GO:0015807 | L-amino acid transport(GO:0015807) |
0.1 | 0.3 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
0.1 | 0.2 | GO:0071929 | alpha-tubulin acetylation(GO:0071929) |
0.1 | 0.2 | GO:0071211 | protein targeting to vacuole involved in autophagy(GO:0071211) |
0.1 | 0.2 | GO:0042264 | peptidyl-aspartic acid hydroxylation(GO:0042264) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428) |
0.1 | 0.3 | GO:0036091 | positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091) |
0.1 | 0.4 | GO:0032261 | purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264) |
0.1 | 0.3 | GO:0051012 | microtubule sliding(GO:0051012) negative regulation of nonmotile primary cilium assembly(GO:1902856) |
0.1 | 0.6 | GO:1990440 | positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440) |
0.1 | 0.6 | GO:0035887 | aortic smooth muscle cell differentiation(GO:0035887) |
0.1 | 0.4 | GO:0061092 | involuntary skeletal muscle contraction(GO:0003011) regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092) |
0.1 | 0.2 | GO:0036465 | synaptic vesicle recycling(GO:0036465) |
0.1 | 0.2 | GO:0060762 | regulation of branching involved in mammary gland duct morphogenesis(GO:0060762) |
0.1 | 0.7 | GO:0044387 | negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387) |
0.1 | 0.2 | GO:1904425 | negative regulation of GTP binding(GO:1904425) |
0.1 | 0.4 | GO:0090234 | regulation of kinetochore assembly(GO:0090234) |
0.1 | 0.2 | GO:0045654 | positive regulation of megakaryocyte differentiation(GO:0045654) |
0.1 | 0.8 | GO:0071378 | growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378) |
0.1 | 1.1 | GO:0071625 | vocalization behavior(GO:0071625) |
0.1 | 0.3 | GO:0030579 | ubiquitin-dependent SMAD protein catabolic process(GO:0030579) |
0.1 | 0.3 | GO:0006616 | SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616) |
0.1 | 0.5 | GO:0031665 | negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665) |
0.1 | 0.3 | GO:0035234 | ectopic germ cell programmed cell death(GO:0035234) |
0.1 | 0.6 | GO:0010650 | positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
0.1 | 1.5 | GO:1900026 | positive regulation of substrate adhesion-dependent cell spreading(GO:1900026) |
0.1 | 0.4 | GO:0098909 | establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909) |
0.1 | 0.1 | GO:0001743 | optic placode formation(GO:0001743) |
0.0 | 0.2 | GO:0001705 | ectoderm formation(GO:0001705) |
0.0 | 0.1 | GO:1901856 | negative regulation of cellular respiration(GO:1901856) |
0.0 | 2.3 | GO:2001222 | regulation of neuron migration(GO:2001222) |
0.0 | 0.9 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
0.0 | 0.3 | GO:1990845 | adaptive thermogenesis(GO:1990845) |
0.0 | 0.3 | GO:0015879 | carnitine transport(GO:0015879) |
0.0 | 0.2 | GO:0038018 | Wnt receptor catabolic process(GO:0038018) |
0.0 | 0.9 | GO:0071357 | type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357) |
0.0 | 0.2 | GO:0061188 | regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188) |
0.0 | 0.3 | GO:0050982 | detection of mechanical stimulus(GO:0050982) |
0.0 | 0.2 | GO:0045903 | positive regulation of translational fidelity(GO:0045903) |
0.0 | 0.2 | GO:0021506 | anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995) |
0.0 | 0.1 | GO:0060353 | regulation of cell adhesion molecule production(GO:0060353) positive regulation of cell adhesion molecule production(GO:0060355) |
0.0 | 0.3 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
0.0 | 2.3 | GO:0050810 | regulation of steroid biosynthetic process(GO:0050810) |
0.0 | 0.2 | GO:0051096 | regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096) |
0.0 | 0.9 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
0.0 | 0.2 | GO:1902775 | mitochondrial large ribosomal subunit assembly(GO:1902775) |
0.0 | 1.1 | GO:0035116 | embryonic hindlimb morphogenesis(GO:0035116) |
0.0 | 0.2 | GO:0035720 | intraciliary anterograde transport(GO:0035720) |
0.0 | 0.3 | GO:0036506 | maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) |
0.0 | 0.4 | GO:0061469 | regulation of type B pancreatic cell proliferation(GO:0061469) |
0.0 | 0.2 | GO:0071372 | cellular response to follicle-stimulating hormone stimulus(GO:0071372) |
0.0 | 0.2 | GO:0034162 | toll-like receptor 9 signaling pathway(GO:0034162) |
0.0 | 0.2 | GO:0031022 | nuclear migration along microfilament(GO:0031022) |
0.0 | 1.5 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
0.0 | 0.1 | GO:0015744 | succinate transport(GO:0015744) |
0.0 | 0.6 | GO:0042178 | xenobiotic catabolic process(GO:0042178) |
0.0 | 1.1 | GO:0030641 | regulation of cellular pH(GO:0030641) |
0.0 | 0.1 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
0.0 | 0.1 | GO:0001865 | NK T cell differentiation(GO:0001865) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138) |
0.0 | 1.2 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
0.0 | 0.4 | GO:0030213 | hyaluronan biosynthetic process(GO:0030213) |
0.0 | 0.3 | GO:0070072 | vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
0.0 | 0.1 | GO:0035964 | COPI-coated vesicle budding(GO:0035964) |
0.0 | 0.3 | GO:0030538 | embryonic genitalia morphogenesis(GO:0030538) embryonic hindgut morphogenesis(GO:0048619) |
0.0 | 0.2 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
0.0 | 0.5 | GO:0003215 | cardiac right ventricle morphogenesis(GO:0003215) |
0.0 | 0.9 | GO:0018345 | protein palmitoylation(GO:0018345) |
0.0 | 0.1 | GO:0032687 | negative regulation of interferon-alpha production(GO:0032687) |
0.0 | 1.2 | GO:0035904 | aorta development(GO:0035904) |
0.0 | 0.7 | GO:0032212 | positive regulation of telomere maintenance via telomerase(GO:0032212) |
0.0 | 0.3 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
0.0 | 0.1 | GO:0097084 | vascular smooth muscle cell development(GO:0097084) |
0.0 | 4.2 | GO:0007416 | synapse assembly(GO:0007416) |
0.0 | 0.2 | GO:0006561 | proline biosynthetic process(GO:0006561) |
0.0 | 0.5 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) |
0.0 | 0.2 | GO:0007296 | vitellogenesis(GO:0007296) |
0.0 | 0.2 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
0.0 | 1.2 | GO:1901998 | toxin transport(GO:1901998) |
0.0 | 0.4 | GO:1900153 | regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153) |
0.0 | 0.1 | GO:2000402 | negative regulation of lymphocyte migration(GO:2000402) |
0.0 | 0.3 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
0.0 | 0.1 | GO:0090035 | misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846) regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035) |
0.0 | 0.2 | GO:0006741 | NADP biosynthetic process(GO:0006741) |
0.0 | 0.3 | GO:0090385 | phagosome-lysosome fusion(GO:0090385) |
0.0 | 0.1 | GO:0045743 | positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743) |
0.0 | 0.2 | GO:0006627 | protein processing involved in protein targeting to mitochondrion(GO:0006627) |
0.0 | 1.1 | GO:0051489 | regulation of filopodium assembly(GO:0051489) |
0.0 | 0.4 | GO:2000369 | regulation of clathrin-mediated endocytosis(GO:2000369) |
0.0 | 0.2 | GO:0007250 | activation of NF-kappaB-inducing kinase activity(GO:0007250) |
0.0 | 0.4 | GO:0010669 | epithelial structure maintenance(GO:0010669) |
0.0 | 0.9 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
0.0 | 0.2 | GO:0042989 | sequestering of actin monomers(GO:0042989) |
0.0 | 0.2 | GO:0045647 | negative regulation of erythrocyte differentiation(GO:0045647) |
0.0 | 0.3 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
0.0 | 0.2 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
0.0 | 0.1 | GO:0030718 | germ-line stem cell population maintenance(GO:0030718) |
0.0 | 0.4 | GO:0097435 | fibril organization(GO:0097435) |
0.0 | 0.3 | GO:0007035 | vacuolar acidification(GO:0007035) |
0.0 | 0.5 | GO:0006152 | purine nucleoside catabolic process(GO:0006152) purine ribonucleoside catabolic process(GO:0046130) |
0.0 | 0.3 | GO:0090141 | positive regulation of mitochondrial fission(GO:0090141) |
0.0 | 0.8 | GO:0001541 | ovarian follicle development(GO:0001541) |
0.0 | 0.2 | GO:0036371 | T-tubule organization(GO:0033292) protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) |
0.0 | 0.3 | GO:0044406 | adhesion of symbiont to host(GO:0044406) |
0.0 | 0.0 | GO:0043313 | regulation of neutrophil degranulation(GO:0043313) regulation of neutrophil activation(GO:1902563) |
0.0 | 0.2 | GO:0002328 | pro-B cell differentiation(GO:0002328) |
0.0 | 0.5 | GO:0006383 | transcription from RNA polymerase III promoter(GO:0006383) |
0.0 | 0.2 | GO:0044130 | negative regulation of growth of symbiont in host(GO:0044130) negative regulation of growth of symbiont involved in interaction with host(GO:0044146) |
0.0 | 0.2 | GO:0032510 | endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510) |
0.0 | 0.2 | GO:0034551 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033) |
0.0 | 0.7 | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184) |
0.0 | 0.1 | GO:0007016 | cytoskeletal anchoring at plasma membrane(GO:0007016) |
0.0 | 0.2 | GO:0051085 | chaperone mediated protein folding requiring cofactor(GO:0051085) |
0.0 | 0.3 | GO:0010574 | regulation of vascular endothelial growth factor production(GO:0010574) |
0.0 | 0.1 | GO:0002347 | response to tumor cell(GO:0002347) |
0.0 | 0.1 | GO:0002339 | B cell selection(GO:0002339) |
0.0 | 0.2 | GO:0061470 | interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619) |
0.0 | 0.1 | GO:0046929 | negative regulation of neurotransmitter secretion(GO:0046929) |
0.0 | 0.2 | GO:0006465 | signal peptide processing(GO:0006465) |
0.0 | 0.2 | GO:0035721 | intraciliary retrograde transport(GO:0035721) |
0.0 | 1.4 | GO:0090630 | activation of GTPase activity(GO:0090630) |
0.0 | 0.1 | GO:0014010 | Schwann cell proliferation(GO:0014010) |
0.0 | 0.3 | GO:0006047 | UDP-N-acetylglucosamine metabolic process(GO:0006047) |
0.0 | 0.2 | GO:0035881 | amacrine cell differentiation(GO:0035881) |
0.0 | 0.1 | GO:0006729 | tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146) |
0.0 | 0.1 | GO:0014886 | transition between slow and fast fiber(GO:0014886) |
0.0 | 0.3 | GO:1901222 | regulation of NIK/NF-kappaB signaling(GO:1901222) |
0.0 | 0.4 | GO:0070059 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059) |
0.0 | 0.1 | GO:0009212 | dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075) |
0.0 | 0.9 | GO:0070936 | protein K48-linked ubiquitination(GO:0070936) |
0.0 | 0.4 | GO:0009268 | response to pH(GO:0009268) |
0.0 | 0.2 | GO:1902187 | negative regulation of viral release from host cell(GO:1902187) |
0.0 | 0.0 | GO:0097026 | dendritic cell dendrite assembly(GO:0097026) |
0.0 | 0.9 | GO:0051289 | protein homotetramerization(GO:0051289) |
0.0 | 5.2 | GO:0006897 | endocytosis(GO:0006897) |
0.0 | 1.2 | GO:0030518 | intracellular steroid hormone receptor signaling pathway(GO:0030518) |
0.0 | 0.1 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
0.0 | 0.0 | GO:1904760 | myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760) |
0.0 | 1.0 | GO:0019722 | calcium-mediated signaling(GO:0019722) |
0.0 | 0.2 | GO:0010758 | regulation of macrophage chemotaxis(GO:0010758) |
0.0 | 0.0 | GO:0000973 | posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) |
0.0 | 0.1 | GO:0061179 | negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179) |
0.0 | 0.0 | GO:0046654 | tetrahydrofolate biosynthetic process(GO:0046654) |
0.0 | 0.0 | GO:0006421 | asparaginyl-tRNA aminoacylation(GO:0006421) |
0.0 | 0.7 | GO:0090263 | positive regulation of canonical Wnt signaling pathway(GO:0090263) |
0.0 | 0.4 | GO:0071774 | response to fibroblast growth factor(GO:0071774) |
0.0 | 0.0 | GO:0010735 | positive regulation of transcription via serum response element binding(GO:0010735) |
0.0 | 0.9 | GO:0031032 | actomyosin structure organization(GO:0031032) |
0.0 | 0.1 | GO:0050667 | homocysteine metabolic process(GO:0050667) |
0.0 | 0.3 | GO:1900087 | positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) |
0.0 | 0.3 | GO:0016578 | histone deubiquitination(GO:0016578) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.5 | 10.0 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
1.7 | 5.2 | GO:0038045 | large latent transforming growth factor-beta complex(GO:0038045) |
0.7 | 3.3 | GO:1903440 | calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440) |
0.5 | 1.6 | GO:1990682 | CSF1-CSF1R complex(GO:1990682) |
0.5 | 4.0 | GO:0097433 | dense body(GO:0097433) |
0.3 | 3.1 | GO:0031254 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
0.3 | 1.7 | GO:1990246 | uniplex complex(GO:1990246) |
0.3 | 1.3 | GO:0043564 | Ku70:Ku80 complex(GO:0043564) |
0.3 | 1.6 | GO:0038039 | G-protein coupled receptor heterodimeric complex(GO:0038039) |
0.3 | 2.1 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
0.3 | 2.1 | GO:0042629 | mast cell granule(GO:0042629) |
0.2 | 1.2 | GO:1990604 | IRE1-TRAF2-ASK1 complex(GO:1990604) |
0.2 | 0.9 | GO:0031084 | BLOC-2 complex(GO:0031084) |
0.2 | 0.7 | GO:0033596 | TSC1-TSC2 complex(GO:0033596) |
0.2 | 1.1 | GO:0097513 | myosin II filament(GO:0097513) |
0.2 | 1.0 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
0.2 | 1.0 | GO:1990037 | Lewy body core(GO:1990037) |
0.2 | 0.7 | GO:0045098 | type III intermediate filament(GO:0045098) |
0.2 | 0.7 | GO:0043293 | apoptosome(GO:0043293) |
0.2 | 0.5 | GO:0043512 | inhibin A complex(GO:0043512) |
0.1 | 0.6 | GO:0060187 | cell pole(GO:0060187) |
0.1 | 1.1 | GO:0016600 | flotillin complex(GO:0016600) Scrib-APC-beta-catenin complex(GO:0034750) |
0.1 | 1.7 | GO:0031209 | SCAR complex(GO:0031209) |
0.1 | 2.4 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
0.1 | 1.9 | GO:0005614 | interstitial matrix(GO:0005614) |
0.1 | 0.5 | GO:0070826 | paraferritin complex(GO:0070826) |
0.1 | 0.4 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
0.1 | 0.4 | GO:0014802 | terminal cisterna(GO:0014802) |
0.1 | 0.3 | GO:0034457 | Mpp10 complex(GO:0034457) |
0.1 | 0.3 | GO:0034272 | phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272) |
0.1 | 1.5 | GO:0042581 | specific granule(GO:0042581) |
0.1 | 0.1 | GO:0098830 | presynaptic endosome(GO:0098830) |
0.1 | 3.2 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
0.1 | 1.1 | GO:0020005 | symbiont-containing vacuole membrane(GO:0020005) |
0.1 | 0.8 | GO:0061574 | ASAP complex(GO:0061574) |
0.1 | 0.2 | GO:0055087 | Ski complex(GO:0055087) |
0.1 | 0.2 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
0.1 | 0.4 | GO:1990130 | Iml1 complex(GO:1990130) |
0.1 | 1.1 | GO:0005604 | basement membrane(GO:0005604) |
0.1 | 0.5 | GO:0005638 | lamin filament(GO:0005638) |
0.1 | 1.2 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
0.1 | 5.5 | GO:0072562 | blood microparticle(GO:0072562) |
0.1 | 0.2 | GO:0031088 | platelet dense granule membrane(GO:0031088) lysosomal lumen(GO:0043202) intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637) |
0.1 | 1.5 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
0.1 | 0.9 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
0.1 | 0.4 | GO:0071439 | clathrin complex(GO:0071439) |
0.1 | 0.3 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
0.1 | 0.2 | GO:0071595 | Nem1-Spo7 phosphatase complex(GO:0071595) |
0.1 | 1.5 | GO:0031430 | M band(GO:0031430) |
0.1 | 0.2 | GO:0044753 | amphisome(GO:0044753) |
0.1 | 0.6 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
0.1 | 0.5 | GO:0005652 | nuclear lamina(GO:0005652) |
0.0 | 3.2 | GO:0009925 | basal plasma membrane(GO:0009925) |
0.0 | 1.3 | GO:0030137 | COPI-coated vesicle(GO:0030137) |
0.0 | 0.5 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
0.0 | 0.3 | GO:0031528 | microvillus membrane(GO:0031528) |
0.0 | 0.4 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
0.0 | 0.5 | GO:0005637 | nuclear inner membrane(GO:0005637) |
0.0 | 0.2 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
0.0 | 0.0 | GO:0019815 | immunoglobulin complex(GO:0019814) B cell receptor complex(GO:0019815) |
0.0 | 0.3 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
0.0 | 5.4 | GO:0030139 | endocytic vesicle(GO:0030139) |
0.0 | 0.3 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
0.0 | 3.5 | GO:0005901 | caveola(GO:0005901) |
0.0 | 0.1 | GO:0001405 | presequence translocase-associated import motor(GO:0001405) |
0.0 | 0.8 | GO:0016514 | SWI/SNF complex(GO:0016514) |
0.0 | 0.2 | GO:0070776 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
0.0 | 0.8 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
0.0 | 0.1 | GO:0016012 | sarcoglycan complex(GO:0016012) |
0.0 | 3.2 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
0.0 | 4.3 | GO:0043204 | perikaryon(GO:0043204) |
0.0 | 1.4 | GO:0000139 | Golgi membrane(GO:0000139) |
0.0 | 1.0 | GO:0097440 | apical dendrite(GO:0097440) |
0.0 | 3.7 | GO:0055037 | recycling endosome(GO:0055037) |
0.0 | 0.6 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
0.0 | 0.5 | GO:0030008 | TRAPP complex(GO:0030008) |
0.0 | 0.6 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
0.0 | 0.2 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
0.0 | 0.2 | GO:0005958 | DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807) |
0.0 | 0.2 | GO:0030478 | actin cap(GO:0030478) |
0.0 | 0.9 | GO:0097610 | cell division site(GO:0032153) cleavage furrow(GO:0032154) cell division site part(GO:0032155) cell surface furrow(GO:0097610) |
0.0 | 0.4 | GO:0070938 | contractile ring(GO:0070938) |
0.0 | 0.2 | GO:0032300 | mismatch repair complex(GO:0032300) |
0.0 | 0.3 | GO:0098984 | asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984) |
0.0 | 0.2 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
0.0 | 0.5 | GO:0016580 | Sin3 complex(GO:0016580) |
0.0 | 4.0 | GO:0001650 | fibrillar center(GO:0001650) |
0.0 | 0.1 | GO:0005916 | fascia adherens(GO:0005916) |
0.0 | 0.5 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
0.0 | 0.2 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
0.0 | 0.7 | GO:0072686 | mitotic spindle(GO:0072686) |
0.0 | 0.2 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
0.0 | 0.6 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
0.0 | 0.1 | GO:0005883 | neurofilament(GO:0005883) |
0.0 | 0.2 | GO:0097542 | ciliary tip(GO:0097542) |
0.0 | 0.2 | GO:0005787 | signal peptidase complex(GO:0005787) |
0.0 | 0.7 | GO:0031901 | early endosome membrane(GO:0031901) |
0.0 | 0.7 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
0.0 | 0.3 | GO:0033276 | transcription factor TFTC complex(GO:0033276) |
0.0 | 0.2 | GO:0031414 | N-terminal protein acetyltransferase complex(GO:0031414) |
0.0 | 0.1 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
0.0 | 0.3 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
0.0 | 0.6 | GO:0032589 | neuron projection membrane(GO:0032589) |
0.0 | 0.4 | GO:0043197 | dendritic spine(GO:0043197) |
0.0 | 0.1 | GO:0030877 | beta-catenin destruction complex(GO:0030877) Wnt signalosome(GO:1990909) |
0.0 | 0.3 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
0.0 | 0.3 | GO:0005921 | gap junction(GO:0005921) |
0.0 | 2.4 | GO:0045177 | apical part of cell(GO:0045177) |
0.0 | 1.7 | GO:0001726 | ruffle(GO:0001726) |
0.0 | 0.1 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
0.0 | 0.2 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
0.0 | 0.9 | GO:0000118 | histone deacetylase complex(GO:0000118) |
0.0 | 0.1 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
0.0 | 0.1 | GO:0042583 | chromaffin granule(GO:0042583) |
0.0 | 0.1 | GO:0042641 | actomyosin(GO:0042641) |
0.0 | 0.6 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
0.0 | 0.3 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.5 | 10.0 | GO:0031721 | haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721) |
2.4 | 7.2 | GO:0036313 | phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313) |
1.9 | 13.3 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
1.4 | 5.6 | GO:0030151 | molybdenum ion binding(GO:0030151) |
1.2 | 5.0 | GO:0050436 | microfibril binding(GO:0050436) |
1.0 | 3.1 | GO:0005344 | oxygen transporter activity(GO:0005344) |
0.8 | 3.3 | GO:0001851 | complement component C3b binding(GO:0001851) |
0.8 | 2.4 | GO:0050656 | 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656) |
0.7 | 3.3 | GO:0097643 | amylin receptor activity(GO:0097643) |
0.7 | 2.0 | GO:0043682 | copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682) |
0.6 | 4.0 | GO:0015091 | ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510) |
0.5 | 2.1 | GO:0004667 | prostaglandin-D synthase activity(GO:0004667) |
0.5 | 1.4 | GO:0004517 | nitric-oxide synthase activity(GO:0004517) |
0.5 | 1.4 | GO:0070890 | L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890) |
0.5 | 1.4 | GO:0015038 | glutathione disulfide oxidoreductase activity(GO:0015038) |
0.4 | 1.6 | GO:0004999 | vasoactive intestinal polypeptide receptor activity(GO:0004999) |
0.4 | 1.1 | GO:0051765 | inositol tetrakisphosphate kinase activity(GO:0051765) |
0.4 | 1.8 | GO:0005030 | neurotrophin receptor activity(GO:0005030) |
0.3 | 2.1 | GO:0004118 | cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) |
0.3 | 1.0 | GO:0036004 | GAF domain binding(GO:0036004) |
0.3 | 1.2 | GO:0004859 | phospholipase inhibitor activity(GO:0004859) phospholipase A2 inhibitor activity(GO:0019834) |
0.3 | 0.9 | GO:0035673 | oligopeptide transmembrane transporter activity(GO:0035673) sphingolipid transporter activity(GO:0046624) |
0.3 | 2.6 | GO:1990239 | steroid hormone binding(GO:1990239) |
0.3 | 1.2 | GO:0004126 | cytidine deaminase activity(GO:0004126) |
0.3 | 1.6 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
0.3 | 1.3 | GO:0008865 | fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
0.2 | 4.5 | GO:0050811 | GABA receptor binding(GO:0050811) |
0.2 | 0.7 | GO:0001875 | lipopolysaccharide receptor activity(GO:0001875) |
0.2 | 11.7 | GO:0005158 | insulin receptor binding(GO:0005158) |
0.2 | 0.7 | GO:0005118 | sevenless binding(GO:0005118) |
0.2 | 0.9 | GO:0004528 | phosphodiesterase I activity(GO:0004528) |
0.2 | 1.4 | GO:0060698 | endoribonuclease inhibitor activity(GO:0060698) |
0.2 | 0.7 | GO:0031752 | D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752) |
0.2 | 1.3 | GO:0051185 | coenzyme transporter activity(GO:0051185) |
0.2 | 2.0 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
0.2 | 0.6 | GO:0071723 | lipopeptide binding(GO:0071723) |
0.2 | 2.5 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
0.2 | 2.6 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
0.2 | 0.7 | GO:0005008 | hepatocyte growth factor-activated receptor activity(GO:0005008) |
0.2 | 1.0 | GO:0019841 | retinal binding(GO:0016918) retinol binding(GO:0019841) |
0.2 | 0.7 | GO:0004111 | creatine kinase activity(GO:0004111) |
0.2 | 0.8 | GO:0042134 | rRNA primary transcript binding(GO:0042134) |
0.2 | 1.0 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
0.2 | 0.5 | GO:0047710 | bis(5'-adenosyl)-triphosphatase activity(GO:0047710) |
0.2 | 0.6 | GO:0097003 | adipokinetic hormone receptor activity(GO:0097003) |
0.2 | 0.3 | GO:0030519 | snoRNP binding(GO:0030519) |
0.2 | 0.8 | GO:0048248 | CXCR3 chemokine receptor binding(GO:0048248) |
0.2 | 0.8 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
0.2 | 1.9 | GO:0003691 | double-stranded telomeric DNA binding(GO:0003691) |
0.2 | 3.2 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
0.2 | 0.9 | GO:0004920 | interleukin-10 receptor activity(GO:0004920) |
0.1 | 3.3 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |
0.1 | 0.6 | GO:0004515 | nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515) |
0.1 | 0.9 | GO:0052654 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
0.1 | 0.8 | GO:0005042 | netrin receptor activity(GO:0005042) |
0.1 | 2.5 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
0.1 | 1.3 | GO:1990715 | mRNA CDS binding(GO:1990715) |
0.1 | 0.5 | GO:0070573 | tripeptidyl-peptidase activity(GO:0008240) metallodipeptidase activity(GO:0070573) |
0.1 | 0.4 | GO:0002153 | steroid receptor RNA activator RNA binding(GO:0002153) |
0.1 | 1.3 | GO:0044548 | S100 protein binding(GO:0044548) |
0.1 | 4.1 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
0.1 | 0.4 | GO:0000992 | polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) |
0.1 | 1.1 | GO:0016151 | nickel cation binding(GO:0016151) |
0.1 | 0.5 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
0.1 | 0.2 | GO:0032139 | dinucleotide insertion or deletion binding(GO:0032139) |
0.1 | 2.1 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
0.1 | 1.4 | GO:0070097 | delta-catenin binding(GO:0070097) |
0.1 | 0.7 | GO:0050786 | RAGE receptor binding(GO:0050786) |
0.1 | 0.9 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
0.1 | 1.0 | GO:0043995 | histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972) |
0.1 | 2.3 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
0.1 | 0.3 | GO:0005124 | scavenger receptor binding(GO:0005124) |
0.1 | 0.7 | GO:0045322 | unmethylated CpG binding(GO:0045322) |
0.1 | 0.7 | GO:0033192 | calmodulin-dependent protein phosphatase activity(GO:0033192) |
0.1 | 1.1 | GO:0045294 | alpha-catenin binding(GO:0045294) |
0.1 | 0.7 | GO:0098821 | BMP receptor activity(GO:0098821) |
0.1 | 4.3 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
0.1 | 0.6 | GO:0008294 | calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294) |
0.1 | 0.9 | GO:0030976 | thiamine pyrophosphate binding(GO:0030976) |
0.1 | 2.2 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
0.1 | 0.5 | GO:0035033 | histone deacetylase regulator activity(GO:0035033) |
0.1 | 0.3 | GO:0030984 | kininogen binding(GO:0030984) |
0.1 | 0.6 | GO:0050897 | cobalt ion binding(GO:0050897) |
0.1 | 0.3 | GO:0017077 | oxidative phosphorylation uncoupler activity(GO:0017077) |
0.1 | 0.8 | GO:0048406 | nerve growth factor binding(GO:0048406) |
0.1 | 3.6 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
0.1 | 0.2 | GO:1990450 | linear polyubiquitin binding(GO:1990450) |
0.1 | 0.5 | GO:0070699 | type II activin receptor binding(GO:0070699) |
0.1 | 0.7 | GO:0097200 | cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200) |
0.1 | 0.6 | GO:0016308 | 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308) |
0.1 | 0.2 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
0.1 | 0.7 | GO:0005432 | calcium:sodium antiporter activity(GO:0005432) |
0.1 | 0.9 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
0.1 | 1.3 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
0.1 | 1.1 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
0.1 | 0.2 | GO:0004735 | pyrroline-5-carboxylate reductase activity(GO:0004735) |
0.1 | 0.2 | GO:0001007 | transcription factor activity, RNA polymerase III transcription factor binding(GO:0001007) |
0.1 | 0.4 | GO:0003831 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831) |
0.1 | 0.4 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
0.1 | 1.3 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
0.1 | 0.4 | GO:0030274 | LIM domain binding(GO:0030274) |
0.1 | 0.7 | GO:0031210 | phosphatidylcholine binding(GO:0031210) |
0.1 | 2.9 | GO:0050840 | extracellular matrix binding(GO:0050840) |
0.1 | 0.3 | GO:0070404 | NADH binding(GO:0070404) |
0.1 | 0.4 | GO:0001609 | G-protein coupled adenosine receptor activity(GO:0001609) |
0.1 | 0.3 | GO:0008761 | UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) |
0.1 | 0.7 | GO:0019215 | intermediate filament binding(GO:0019215) |
0.1 | 0.7 | GO:0017166 | vinculin binding(GO:0017166) |
0.1 | 0.7 | GO:0016832 | aldehyde-lyase activity(GO:0016832) |
0.1 | 1.2 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
0.0 | 0.0 | GO:0004637 | phosphoribosylamine-glycine ligase activity(GO:0004637) |
0.0 | 0.7 | GO:0048273 | mitogen-activated protein kinase p38 binding(GO:0048273) |
0.0 | 0.2 | GO:0010484 | H3 histone acetyltransferase activity(GO:0010484) |
0.0 | 0.1 | GO:0017153 | sodium:dicarboxylate symporter activity(GO:0017153) |
0.0 | 0.4 | GO:0002162 | dystroglycan binding(GO:0002162) |
0.0 | 0.2 | GO:0071532 | ankyrin repeat binding(GO:0071532) |
0.0 | 0.3 | GO:0070644 | vitamin D response element binding(GO:0070644) |
0.0 | 0.3 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
0.0 | 0.3 | GO:0015093 | iron ion transmembrane transporter activity(GO:0005381) ferrous iron transmembrane transporter activity(GO:0015093) |
0.0 | 0.2 | GO:0046403 | polynucleotide 3'-phosphatase activity(GO:0046403) |
0.0 | 0.3 | GO:0016401 | palmitoyl-CoA oxidase activity(GO:0016401) |
0.0 | 1.3 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
0.0 | 1.5 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
0.0 | 0.3 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
0.0 | 0.1 | GO:0008192 | RNA guanylyltransferase activity(GO:0008192) |
0.0 | 6.8 | GO:0017124 | SH3 domain binding(GO:0017124) |
0.0 | 0.8 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.0 | 0.2 | GO:0048495 | Roundabout binding(GO:0048495) |
0.0 | 0.2 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
0.0 | 0.2 | GO:0008545 | JUN kinase kinase activity(GO:0008545) |
0.0 | 0.2 | GO:0034235 | GPI anchor binding(GO:0034235) |
0.0 | 0.2 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
0.0 | 0.9 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
0.0 | 0.2 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
0.0 | 0.6 | GO:0035497 | cAMP response element binding(GO:0035497) |
0.0 | 0.4 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
0.0 | 0.6 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
0.0 | 2.9 | GO:0008083 | growth factor activity(GO:0008083) |
0.0 | 2.5 | GO:0005178 | integrin binding(GO:0005178) |
0.0 | 0.3 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
0.0 | 0.9 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
0.0 | 1.7 | GO:0030507 | spectrin binding(GO:0030507) |
0.0 | 1.2 | GO:0001671 | ATPase activator activity(GO:0001671) |
0.0 | 0.5 | GO:0071949 | FAD binding(GO:0071949) |
0.0 | 0.3 | GO:0005243 | gap junction channel activity(GO:0005243) |
0.0 | 0.2 | GO:1990932 | 5.8S rRNA binding(GO:1990932) |
0.0 | 2.2 | GO:0008201 | heparin binding(GO:0008201) |
0.0 | 0.2 | GO:1990599 | 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599) |
0.0 | 0.3 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062) |
0.0 | 0.4 | GO:0050780 | dopamine receptor binding(GO:0050780) |
0.0 | 1.4 | GO:0016811 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811) |
0.0 | 0.3 | GO:0035004 | 1-phosphatidylinositol-3-kinase activity(GO:0016303) phosphatidylinositol 3-kinase activity(GO:0035004) |
0.0 | 0.6 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.0 | 4.3 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
0.0 | 0.6 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
0.0 | 0.1 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
0.0 | 0.2 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
0.0 | 0.4 | GO:0070566 | adenylyltransferase activity(GO:0070566) |
0.0 | 0.3 | GO:0019531 | secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531) |
0.0 | 0.2 | GO:0035325 | Toll-like receptor binding(GO:0035325) |
0.0 | 0.1 | GO:0016971 | flavin-linked sulfhydryl oxidase activity(GO:0016971) |
0.0 | 0.8 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
0.0 | 0.2 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
0.0 | 0.2 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
0.0 | 1.5 | GO:0030674 | protein binding, bridging(GO:0030674) |
0.0 | 0.8 | GO:0015485 | cholesterol binding(GO:0015485) |
0.0 | 0.1 | GO:0005025 | transforming growth factor beta receptor activity, type I(GO:0005025) |
0.0 | 0.0 | GO:0008534 | oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534) |
0.0 | 0.1 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
0.0 | 0.3 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
0.0 | 0.1 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
0.0 | 0.2 | GO:0004576 | oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
0.0 | 0.2 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
0.0 | 0.2 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
0.0 | 0.1 | GO:0004016 | adenylate cyclase activity(GO:0004016) |
0.0 | 0.5 | GO:0005484 | SNAP receptor activity(GO:0005484) |
0.0 | 0.1 | GO:0004416 | hydroxyacylglutathione hydrolase activity(GO:0004416) |
0.0 | 0.1 | GO:0015143 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
0.0 | 0.5 | GO:0016810 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810) |
0.0 | 0.1 | GO:0016884 | carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884) |
0.0 | 0.3 | GO:0008013 | beta-catenin binding(GO:0008013) |
0.0 | 1.7 | GO:0043021 | ribonucleoprotein complex binding(GO:0043021) |
0.0 | 0.1 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
0.0 | 3.0 | GO:0030695 | GTPase regulator activity(GO:0030695) |
0.0 | 1.1 | GO:0008237 | metallopeptidase activity(GO:0008237) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 2.3 | SA_MMP_CYTOKINE_CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
0.2 | 2.3 | PID_INTEGRIN2_PATHWAY | Beta2 integrin cell surface interactions |
0.2 | 7.3 | PID_EPO_PATHWAY | EPO signaling pathway |
0.1 | 3.6 | ST_GA12_PATHWAY | G alpha 12 Pathway |
0.1 | 4.5 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
0.1 | 6.4 | PID_ERBB1_INTERNALIZATION_PATHWAY | Internalization of ErbB1 |
0.1 | 0.6 | PID_ECADHERIN_KERATINOCYTE_PATHWAY | E-cadherin signaling in keratinocytes |
0.1 | 7.9 | PID_AJDISS_2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
0.1 | 1.6 | PID_ANTHRAX_PATHWAY | Cellular roles of Anthrax toxin |
0.1 | 6.2 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
0.1 | 2.8 | PID_NETRIN_PATHWAY | Netrin-mediated signaling events |
0.1 | 0.4 | PID_S1P_S1P2_PATHWAY | S1P2 pathway |
0.1 | 2.1 | PID_NCADHERIN_PATHWAY | N-cadherin signaling events |
0.1 | 2.5 | PID_PI3K_PLC_TRK_PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
0.1 | 2.0 | PID_INTEGRIN_A9B1_PATHWAY | Alpha9 beta1 integrin signaling events |
0.1 | 1.7 | PID_DNA_PK_PATHWAY | DNA-PK pathway in nonhomologous end joining |
0.1 | 1.6 | PID_S1P_META_PATHWAY | Sphingosine 1-phosphate (S1P) pathway |
0.1 | 2.7 | PID_SHP2_PATHWAY | SHP2 signaling |
0.1 | 1.7 | PID_ECADHERIN_NASCENT_AJ_PATHWAY | E-cadherin signaling in the nascent adherens junction |
0.1 | 1.6 | PID_PI3KCI_AKT_PATHWAY | Class I PI3K signaling events mediated by Akt |
0.1 | 2.3 | PID_ENDOTHELIN_PATHWAY | Endothelins |
0.1 | 4.1 | PID_REG_GR_PATHWAY | Glucocorticoid receptor regulatory network |
0.1 | 0.4 | PID_BARD1_PATHWAY | BARD1 signaling events |
0.1 | 7.6 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
0.1 | 1.0 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
0.0 | 8.8 | NABA_SECRETED_FACTORS | Genes encoding secreted soluble factors |
0.0 | 3.1 | PID_ERA_GENOMIC_PATHWAY | Validated nuclear estrogen receptor alpha network |
0.0 | 5.4 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.0 | 1.0 | ST_GAQ_PATHWAY | G alpha q Pathway |
0.0 | 0.6 | PID_IL6_7_PATHWAY | IL6-mediated signaling events |
0.0 | 1.3 | ST_WNT_BETA_CATENIN_PATHWAY | Wnt/beta-catenin Pathway |
0.0 | 1.2 | PID_HIF2PATHWAY | HIF-2-alpha transcription factor network |
0.0 | 1.0 | PID_TRKR_PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
0.0 | 2.2 | PID_PDGFRB_PATHWAY | PDGFR-beta signaling pathway |
0.0 | 1.4 | PID_AP1_PATHWAY | AP-1 transcription factor network |
0.0 | 1.5 | PID_AR_TF_PATHWAY | Regulation of Androgen receptor activity |
0.0 | 1.0 | PID_TNF_PATHWAY | TNF receptor signaling pathway |
0.0 | 1.3 | PID_LKB1_PATHWAY | LKB1 signaling events |
0.0 | 1.0 | PID_BMP_PATHWAY | BMP receptor signaling |
0.0 | 0.4 | ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY | PI3K Pathway |
0.0 | 0.8 | PID_P75_NTR_PATHWAY | p75(NTR)-mediated signaling |
0.0 | 0.8 | PID_CASPASE_PATHWAY | Caspase cascade in apoptosis |
0.0 | 0.2 | PID_EPHA_FWDPATHWAY | EPHA forward signaling |
0.0 | 0.4 | PID_RXR_VDR_PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
0.0 | 0.2 | PID_IL2_STAT5_PATHWAY | IL2 signaling events mediated by STAT5 |
0.0 | 0.5 | PID_TELOMERASE_PATHWAY | Regulation of Telomerase |
0.0 | 0.4 | PID_ARF_3PATHWAY | Arf1 pathway |
0.0 | 0.1 | PID_TRAIL_PATHWAY | TRAIL signaling pathway |
0.0 | 0.1 | PID_ERBB2_ERBB3_PATHWAY | ErbB2/ErbB3 signaling events |
0.0 | 0.2 | PID_ILK_PATHWAY | Integrin-linked kinase signaling |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 3.3 | REACTOME_REGULATION_OF_COMPLEMENT_CASCADE | Genes involved in Regulation of Complement cascade |
0.5 | 3.0 | REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
0.4 | 8.0 | REACTOME_SOS_MEDIATED_SIGNALLING | Genes involved in SOS-mediated signalling |
0.3 | 2.4 | REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
0.3 | 4.1 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
0.3 | 1.3 | REACTOME_COMMON_PATHWAY | Genes involved in Common Pathway |
0.2 | 3.4 | REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 | Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 |
0.2 | 2.0 | REACTOME_SIGNALING_BY_ACTIVATED_POINT_MUTANTS_OF_FGFR1 | Genes involved in Signaling by activated point mutants of FGFR1 |
0.2 | 2.6 | REACTOME_CS_DS_DEGRADATION | Genes involved in CS/DS degradation |
0.2 | 1.3 | REACTOME_THE_NLRP3_INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
0.2 | 0.7 | REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 | Genes involved in IKK complex recruitment mediated by RIP1 |
0.2 | 1.1 | REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
0.2 | 1.8 | REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
0.2 | 5.3 | REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
0.1 | 3.1 | REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
0.1 | 0.7 | REACTOME_PLATELET_CALCIUM_HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
0.1 | 1.1 | REACTOME_KERATAN_SULFATE_DEGRADATION | Genes involved in Keratan sulfate degradation |
0.1 | 0.8 | REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
0.1 | 0.5 | REACTOME_GLYCOPROTEIN_HORMONES | Genes involved in Glycoprotein hormones |
0.1 | 4.2 | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
0.1 | 4.4 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | Genes involved in Ion transport by P-type ATPases |
0.1 | 2.3 | REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING | Genes involved in DCC mediated attractive signaling |
0.1 | 2.1 | REACTOME_CGMP_EFFECTS | Genes involved in cGMP effects |
0.1 | 0.1 | REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS | Genes involved in Class A/1 (Rhodopsin-like receptors) |
0.1 | 1.4 | REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
0.1 | 1.1 | REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
0.1 | 1.5 | REACTOME_INTEGRATION_OF_PROVIRUS | Genes involved in Integration of provirus |
0.1 | 2.2 | REACTOME_DARPP_32_EVENTS | Genes involved in DARPP-32 events |
0.1 | 3.3 | REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
0.1 | 0.9 | REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
0.1 | 2.5 | REACTOME_CA_DEPENDENT_EVENTS | Genes involved in Ca-dependent events |
0.1 | 0.6 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
0.1 | 0.8 | REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
0.1 | 2.2 | REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING | Genes involved in Sema4D in semaphorin signaling |
0.1 | 0.6 | REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
0.1 | 0.8 | REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
0.1 | 1.6 | REACTOME_NETRIN1_SIGNALING | Genes involved in Netrin-1 signaling |
0.1 | 1.0 | REACTOME_ACTIVATION_OF_GENES_BY_ATF4 | Genes involved in Activation of Genes by ATF4 |
0.1 | 0.7 | REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
0.1 | 3.1 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
0.1 | 3.5 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
0.1 | 0.5 | REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
0.0 | 0.8 | REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
0.0 | 1.4 | REACTOME_MYOGENESIS | Genes involved in Myogenesis |
0.0 | 1.5 | REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT | Genes involved in ABC-family proteins mediated transport |
0.0 | 0.6 | REACTOME_P38MAPK_EVENTS | Genes involved in p38MAPK events |
0.0 | 1.0 | REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
0.0 | 1.7 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
0.0 | 2.5 | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
0.0 | 0.5 | REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
0.0 | 1.1 | REACTOME_TIGHT_JUNCTION_INTERACTIONS | Genes involved in Tight junction interactions |
0.0 | 1.2 | REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
0.0 | 0.8 | REACTOME_SYNTHESIS_OF_PC | Genes involved in Synthesis of PC |
0.0 | 0.8 | REACTOME_SIGNALING_BY_PDGF | Genes involved in Signaling by PDGF |
0.0 | 0.4 | REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS | Genes involved in Nucleotide-like (purinergic) receptors |
0.0 | 1.2 | REACTOME_GLUCOSE_TRANSPORT | Genes involved in Glucose transport |
0.0 | 0.4 | REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
0.0 | 0.7 | REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
0.0 | 0.2 | REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR | Genes involved in Trafficking and processing of endosomal TLR |
0.0 | 0.4 | REACTOME_PURINE_SALVAGE | Genes involved in Purine salvage |
0.0 | 0.5 | REACTOME_RNA_POL_III_CHAIN_ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
0.0 | 0.9 | REACTOME_INTERFERON_ALPHA_BETA_SIGNALING | Genes involved in Interferon alpha/beta signaling |
0.0 | 0.4 | REACTOME_ERK_MAPK_TARGETS | Genes involved in ERK/MAPK targets |
0.0 | 0.4 | REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
0.0 | 2.4 | REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
0.0 | 0.3 | REACTOME_NOD1_2_SIGNALING_PATHWAY | Genes involved in NOD1/2 Signaling Pathway |
0.0 | 0.3 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
0.0 | 0.2 | REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 | Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
0.0 | 0.4 | REACTOME_GAP_JUNCTION_DEGRADATION | Genes involved in Gap junction degradation |
0.0 | 0.2 | REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL | Genes involved in NF-kB is activated and signals survival |
0.0 | 0.2 | REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |
0.0 | 0.8 | REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
0.0 | 0.6 | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
0.0 | 0.9 | REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
0.0 | 0.3 | REACTOME_NEPHRIN_INTERACTIONS | Genes involved in Nephrin interactions |
0.0 | 0.9 | REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ | Genes involved in Response to elevated platelet cytosolic Ca2+ |
0.0 | 0.5 | REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 | Genes involved in Nuclear signaling by ERBB4 |
0.0 | 0.1 | REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
0.0 | 0.3 | REACTOME_KERATAN_SULFATE_KERATIN_METABOLISM | Genes involved in Keratan sulfate/keratin metabolism |
0.0 | 0.4 | REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
0.0 | 0.3 | REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
0.0 | 0.1 | REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
0.0 | 0.5 | REACTOME_TOLL_RECEPTOR_CASCADES | Genes involved in Toll Receptor Cascades |
0.0 | 0.2 | REACTOME_METABOLISM_OF_POLYAMINES | Genes involved in Metabolism of polyamines |
0.0 | 0.3 | REACTOME_RAP1_SIGNALLING | Genes involved in Rap1 signalling |
0.0 | 0.2 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
0.0 | 0.3 | REACTOME_SIGNALING_BY_BMP | Genes involved in Signaling by BMP |