Motif ID: Prrx1_Isx_Prrxl1

Z-value: 0.855

Transcription factors associated with Prrx1_Isx_Prrxl1:

Gene SymbolEntrez IDGene Name
Isx ENSMUSG00000031621.3 Isx
Prrx1 ENSMUSG00000026586.10 Prrx1
Prrxl1 ENSMUSG00000041730.7 Prrxl1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Prrx1mm10_v2_chr1_-_163313661_1633137100.702.7e-07Click!
Prrxl1mm10_v2_chr14_+_32599922_32599932-0.533.3e-04Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Prrx1_Isx_Prrxl1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_79386943 7.199 ENSMUST00000053718.8
ENSMUST00000179243.1
Rlbp1

retinaldehyde binding protein 1

chr2_-_71546745 5.713 ENSMUST00000024159.6
Dlx2
distal-less homeobox 2
chr3_+_122419772 5.573 ENSMUST00000029766.4
Bcar3
breast cancer anti-estrogen resistance 3
chr15_-_8710734 4.979 ENSMUST00000005493.7
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr15_-_8710409 3.507 ENSMUST00000157065.1
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr14_-_101609033 3.501 ENSMUST00000161991.1
ENSMUST00000100340.3
Tbc1d4

TBC1 domain family, member 4

chr12_+_9029982 3.417 ENSMUST00000085741.1
Ttc32
tetratricopeptide repeat domain 32
chr12_+_117843489 3.348 ENSMUST00000021592.9
Cdca7l
cell division cycle associated 7 like
chrM_+_11734 3.176 ENSMUST00000082418.1
mt-Nd5
mitochondrially encoded NADH dehydrogenase 5
chr17_+_78508063 3.096 ENSMUST00000024880.9
Vit
vitrin
chr15_-_37459327 3.095 ENSMUST00000119730.1
ENSMUST00000120746.1
Ncald

neurocalcin delta

chr8_-_106573461 3.013 ENSMUST00000073722.5
Gm10073
predicted pseudogene 10073
chr12_+_79297345 3.005 ENSMUST00000079533.5
ENSMUST00000171210.1
Rad51b

RAD51 homolog B

chr2_+_91257323 3.005 ENSMUST00000111349.2
ENSMUST00000131711.1
Pacsin3

protein kinase C and casein kinase substrate in neurons 3

chr10_-_42583628 2.883 ENSMUST00000019938.4
Nr2e1
nuclear receptor subfamily 2, group E, member 1
chr8_+_94172618 2.802 ENSMUST00000034214.6
Mt2
metallothionein 2
chr18_-_78206408 2.788 ENSMUST00000163367.1
Slc14a2
solute carrier family 14 (urea transporter), member 2
chr4_-_58499398 2.766 ENSMUST00000107570.1
Lpar1
lysophosphatidic acid receptor 1
chr3_-_59220150 2.755 ENSMUST00000170388.1
P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr9_+_35423582 2.711 ENSMUST00000154652.1
Cdon
cell adhesion molecule-related/down-regulated by oncogenes
chr2_+_116067213 2.660 ENSMUST00000152412.1
G630016G05Rik
RIKEN cDNA G630016G05 gene
chr3_-_98339921 2.654 ENSMUST00000065793.5
Phgdh
3-phosphoglycerate dehydrogenase
chr14_-_118052235 2.652 ENSMUST00000022725.2
Dct
dopachrome tautomerase
chrX_+_170010744 2.651 ENSMUST00000178789.1
Gm21887
predicted gene, 21887
chr3_+_159839729 2.535 ENSMUST00000068952.5
Wls
wntless homolog (Drosophila)
chr1_-_152625212 2.392 ENSMUST00000027760.7
Rgl1
ral guanine nucleotide dissociation stimulator,-like 1
chr19_-_43912392 2.279 ENSMUST00000026209.4
Dnmbp
dynamin binding protein
chr4_+_5724304 2.207 ENSMUST00000108380.1
Fam110b
family with sequence similarity 110, member B
chrY_+_90785442 2.105 ENSMUST00000177591.1
ENSMUST00000177671.1
ENSMUST00000179077.1
Erdr1


erythroid differentiation regulator 1


chr8_-_46294592 2.103 ENSMUST00000058636.7
Helt
helt bHLH transcription factor
chr4_-_134767940 2.044 ENSMUST00000037828.6
Ldlrap1
low density lipoprotein receptor adaptor protein 1
chr11_-_117873433 2.030 ENSMUST00000033230.7
Tha1
threonine aldolase 1
chr16_-_45693658 1.999 ENSMUST00000114562.2
ENSMUST00000036617.7
Tmprss7

transmembrane serine protease 7

chr2_+_152736244 1.933 ENSMUST00000038368.8
ENSMUST00000109824.1
Id1

inhibitor of DNA binding 1

chr2_+_20737306 1.920 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4

enhancer trap locus 4

chr3_+_66219909 1.882 ENSMUST00000029421.5
Ptx3
pentraxin related gene
chr2_+_91256813 1.882 ENSMUST00000144394.1
ENSMUST00000028694.5
ENSMUST00000168916.1
ENSMUST00000156919.1
Pacsin3



protein kinase C and casein kinase substrate in neurons 3



chr8_-_105568298 1.810 ENSMUST00000005849.5
Agrp
agouti related protein
chr2_-_34913976 1.765 ENSMUST00000028232.3
Phf19
PHD finger protein 19
chr18_-_39487096 1.734 ENSMUST00000097592.2
ENSMUST00000115571.1
Nr3c1

nuclear receptor subfamily 3, group C, member 1

chr6_-_34317442 1.725 ENSMUST00000154655.1
ENSMUST00000102980.4
Akr1b3

aldo-keto reductase family 1, member B3 (aldose reductase)

chr3_-_49757257 1.681 ENSMUST00000035931.7
Pcdh18
protocadherin 18
chr10_+_56377300 1.595 ENSMUST00000068581.7
Gja1
gap junction protein, alpha 1
chr4_-_14621805 1.569 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr17_+_56613392 1.523 ENSMUST00000080492.5
Rpl36
ribosomal protein L36
chr15_-_9140374 1.493 ENSMUST00000096482.3
ENSMUST00000110585.2
Skp2

S-phase kinase-associated protein 2 (p45)

chr8_+_23411490 1.474 ENSMUST00000033952.7
Sfrp1
secreted frizzled-related protein 1
chr18_+_60774510 1.461 ENSMUST00000025511.3
Rps14
ribosomal protein S14
chr10_-_13324160 1.441 ENSMUST00000105545.4
Phactr2
phosphatase and actin regulator 2
chr10_-_88605017 1.406 ENSMUST00000119185.1
ENSMUST00000121629.1
Mybpc1

myosin binding protein C, slow-type

chr7_+_126862431 1.404 ENSMUST00000132808.1
Hirip3
HIRA interacting protein 3
chr13_+_104229366 1.325 ENSMUST00000022227.6
Cenpk
centromere protein K
chr9_+_92457369 1.261 ENSMUST00000034941.7
Plscr4
phospholipid scramblase 4
chr18_+_60774675 1.240 ENSMUST00000118551.1
Rps14
ribosomal protein S14
chr11_+_90030295 1.237 ENSMUST00000092788.3
Tmem100
transmembrane protein 100
chr4_-_32923455 1.226 ENSMUST00000035719.4
ENSMUST00000084749.1
Ankrd6

ankyrin repeat domain 6

chr3_-_66296807 1.225 ENSMUST00000029419.7
Veph1
ventricular zone expressed PH domain-containing 1
chr3_+_86070915 1.208 ENSMUST00000182666.1
Sh3d19
SH3 domain protein D19
chr19_+_5474681 1.197 ENSMUST00000165485.1
ENSMUST00000166253.1
ENSMUST00000167371.1
ENSMUST00000167855.1
ENSMUST00000070118.7
Efemp2




epidermal growth factor-containing fibulin-like extracellular matrix protein 2




chr3_+_84593547 1.175 ENSMUST00000062623.3
Tigd4
tigger transposable element derived 4
chr15_+_98571004 1.134 ENSMUST00000023728.6
4930415O20Rik
RIKEN cDNA 4930415O20 gene
chr2_+_14873656 1.111 ENSMUST00000114718.1
ENSMUST00000114719.1
Cacnb2

calcium channel, voltage-dependent, beta 2 subunit

chr19_+_53140430 1.108 ENSMUST00000111741.2
Add3
adducin 3 (gamma)
chr15_+_85510812 1.102 ENSMUST00000079690.2
Gm4825
predicted pseudogene 4825
chr9_+_64281575 1.099 ENSMUST00000034964.6
Tipin
timeless interacting protein
chr3_-_88410295 1.095 ENSMUST00000056370.7
Pmf1
polyamine-modulated factor 1
chr2_-_116067391 1.091 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr1_-_163725123 1.088 ENSMUST00000159679.1
Mettl11b
methyltransferase like 11B
chr5_+_15516489 1.085 ENSMUST00000178227.1
Gm21847
predicted gene, 21847
chr2_+_52038005 1.071 ENSMUST00000065927.5
Tnfaip6
tumor necrosis factor alpha induced protein 6
chr11_-_115419917 1.071 ENSMUST00000106537.1
ENSMUST00000043931.2
ENSMUST00000073791.3
Atp5h


ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d


chr5_-_124095749 1.025 ENSMUST00000031354.4
Abcb9
ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr3_-_141982224 1.016 ENSMUST00000029948.8
Bmpr1b
bone morphogenetic protein receptor, type 1B
chr14_+_73237891 1.002 ENSMUST00000044405.6
Lpar6
lysophosphatidic acid receptor 6
chr7_+_67655414 0.962 ENSMUST00000107470.1
Ttc23
tetratricopeptide repeat domain 23
chr3_-_41742471 0.943 ENSMUST00000026866.8
Sclt1
sodium channel and clathrin linker 1
chr9_-_48911067 0.918 ENSMUST00000003826.7
Htr3a
5-hydroxytryptamine (serotonin) receptor 3A
chr1_-_56969864 0.914 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr12_-_110978981 0.913 ENSMUST00000135131.1
ENSMUST00000043459.6
ENSMUST00000128353.1
Ankrd9


ankyrin repeat domain 9


chr8_-_105637403 0.893 ENSMUST00000182046.1
Gm5914
predicted gene 5914
chr14_-_6973818 0.885 ENSMUST00000166618.1
Gm6356
predicted gene 6356
chr11_+_109543694 0.880 ENSMUST00000106696.1
Arsg
arylsulfatase G
chr8_-_105966038 0.858 ENSMUST00000116429.2
ENSMUST00000034370.9
Slc12a4

solute carrier family 12, member 4

chr2_-_84425258 0.857 ENSMUST00000074262.2
Calcrl
calcitonin receptor-like
chr9_+_118478344 0.850 ENSMUST00000035020.8
Eomes
eomesodermin homolog (Xenopus laevis)
chr12_-_56535047 0.843 ENSMUST00000178477.2
Nkx2-1
NK2 homeobox 1
chr11_-_79504078 0.836 ENSMUST00000164465.2
Omg
oligodendrocyte myelin glycoprotein
chr13_-_105271039 0.824 ENSMUST00000069686.6
Rnf180
ring finger protein 180
chr4_+_3940747 0.808 ENSMUST00000119403.1
Chchd7
coiled-coil-helix-coiled-coil-helix domain containing 7
chr3_+_41742615 0.807 ENSMUST00000146165.1
ENSMUST00000119572.1
ENSMUST00000108065.2
ENSMUST00000120167.1
ENSMUST00000026867.7
ENSMUST00000026868.7
D3Ertd751e





DNA segment, Chr 3, ERATO Doi 751, expressed





chr19_+_38395980 0.802 ENSMUST00000054098.2
Slc35g1
solute carrier family 35, member G1
chr17_+_46496753 0.798 ENSMUST00000046497.6
Dnph1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr9_-_71163224 0.797 ENSMUST00000074465.2
Aqp9
aquaporin 9
chr13_-_81570640 0.788 ENSMUST00000109565.2
Gpr98
G protein-coupled receptor 98
chr7_+_132610620 0.780 ENSMUST00000033241.5
Lhpp
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
chr4_-_14621669 0.775 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr1_+_167598384 0.774 ENSMUST00000015987.3
Rxrg
retinoid X receptor gamma
chr7_+_126695355 0.770 ENSMUST00000130498.1
Bola2
bolA-like 2 (E. coli)
chr11_+_113684412 0.745 ENSMUST00000042227.8
ENSMUST00000123466.1
ENSMUST00000106621.3
D11Wsu47e


DNA segment, Chr 11, Wayne State University 47, expressed


chr7_+_140941550 0.740 ENSMUST00000079403.4
Athl1
ATH1, acid trehalase-like 1 (yeast)
chr9_+_80165079 0.739 ENSMUST00000184480.1
Myo6
myosin VI
chr3_+_88579602 0.732 ENSMUST00000035785.7
Ssr2
signal sequence receptor, beta
chr5_-_62766153 0.731 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr4_-_14621494 0.726 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chrX_+_99975570 0.720 ENSMUST00000113779.1
ENSMUST00000113776.1
ENSMUST00000113775.1
ENSMUST00000113780.1
ENSMUST00000113778.1
ENSMUST00000113781.1
ENSMUST00000113783.1
ENSMUST00000071453.2
ENSMUST00000113777.1
Eda








ectodysplasin-A








chr15_+_99006056 0.707 ENSMUST00000079818.3
Gm8973
predicted gene 8973
chr13_-_74807913 0.702 ENSMUST00000065629.4
Cast
calpastatin
chr13_+_49504774 0.693 ENSMUST00000051504.7
Ecm2
extracellular matrix protein 2, female organ and adipocyte specific
chr11_-_12027958 0.693 ENSMUST00000109654.1
Grb10
growth factor receptor bound protein 10
chr2_-_155945282 0.693 ENSMUST00000040162.2
Gdf5
growth differentiation factor 5
chrX_-_134541847 0.691 ENSMUST00000054213.4
Timm8a1
translocase of inner mitochondrial membrane 8A1
chr2_-_160619971 0.685 ENSMUST00000109473.1
Gm14221
predicted gene 14221
chr19_-_50678642 0.681 ENSMUST00000072685.6
ENSMUST00000164039.2
Sorcs1

VPS10 domain receptor protein SORCS 1

chr4_+_154964117 0.671 ENSMUST00000030931.4
ENSMUST00000070953.4
Pank4

pantothenate kinase 4

chr3_+_87906842 0.670 ENSMUST00000159492.1
Hdgf
hepatoma-derived growth factor
chr7_+_102441685 0.661 ENSMUST00000033283.9
Rrm1
ribonucleotide reductase M1
chr1_+_167598450 0.658 ENSMUST00000111386.1
ENSMUST00000111384.1
Rxrg

retinoid X receptor gamma

chr1_-_133610253 0.648 ENSMUST00000166915.1
Snrpe
small nuclear ribonucleoprotein E
chr11_+_53433299 0.647 ENSMUST00000018382.6
Gdf9
growth differentiation factor 9
chr1_+_58210397 0.644 ENSMUST00000040442.5
Aox4
aldehyde oxidase 4
chr6_+_36388055 0.643 ENSMUST00000172278.1
Chrm2
cholinergic receptor, muscarinic 2, cardiac
chr18_+_69593361 0.637 ENSMUST00000114978.2
ENSMUST00000114977.1
Tcf4

transcription factor 4

chr13_+_94788873 0.619 ENSMUST00000046644.5
Tbca
tubulin cofactor A
chr5_-_87482258 0.609 ENSMUST00000079811.6
ENSMUST00000144144.1
Ugt2a1

UDP glucuronosyltransferase 2 family, polypeptide A1

chr9_-_89705017 0.607 ENSMUST00000058488.6
Tmed3
transmembrane emp24 domain containing 3
chr19_-_19001099 0.600 ENSMUST00000040153.8
ENSMUST00000112828.1
Rorb

RAR-related orphan receptor beta

chr10_+_128747850 0.590 ENSMUST00000163377.2
Wibg
within bgcn homolog (Drosophila)
chr4_+_15881255 0.590 ENSMUST00000029876.1
Calb1
calbindin 1
chr12_-_73047179 0.590 ENSMUST00000050029.7
Six1
sine oculis-related homeobox 1
chr9_+_66946057 0.583 ENSMUST00000040917.7
ENSMUST00000127896.1
Rps27l

ribosomal protein S27-like

chr2_-_67194695 0.573 ENSMUST00000147939.1
Gm13598
predicted gene 13598
chr18_+_35553401 0.570 ENSMUST00000181664.1
Snhg4
small nucleolar RNA host gene 4 (non-protein coding)
chr5_+_45493374 0.565 ENSMUST00000046122.6
Lap3
leucine aminopeptidase 3
chr4_+_102589687 0.558 ENSMUST00000097949.4
ENSMUST00000106901.1
Pde4b

phosphodiesterase 4B, cAMP specific

chr9_+_99629823 0.545 ENSMUST00000112886.2
Dzip1l
DAZ interacting protein 1-like
chr4_-_110292719 0.545 ENSMUST00000106601.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr12_-_80643799 0.543 ENSMUST00000166931.1
Erh
enhancer of rudimentary homolog (Drosophila)
chrX_+_106015699 0.531 ENSMUST00000033582.4
Cox7b
cytochrome c oxidase subunit VIIb
chr17_+_27556668 0.526 ENSMUST00000117254.1
ENSMUST00000118570.1
Hmga1

high mobility group AT-hook 1

chr3_+_133338936 0.523 ENSMUST00000150386.1
ENSMUST00000125858.1
Ppa2

pyrophosphatase (inorganic) 2

chrX_-_59166080 0.521 ENSMUST00000119306.1
Fgf13
fibroblast growth factor 13
chr1_-_56969827 0.519 ENSMUST00000176759.1
Satb2
special AT-rich sequence binding protein 2
chr2_-_33942111 0.514 ENSMUST00000130988.1
ENSMUST00000127936.1
ENSMUST00000134271.1
Gm13403


predicted gene 13403


chr2_-_29787622 0.507 ENSMUST00000177467.1
ENSMUST00000113807.3
Trub2

TruB pseudouridine (psi) synthase homolog 2 (E. coli)

chrX_-_134111852 0.485 ENSMUST00000033610.6
Nox1
NADPH oxidase 1
chr17_+_27556613 0.483 ENSMUST00000117600.1
ENSMUST00000114888.3
Hmga1

high mobility group AT-hook 1

chr1_-_144177259 0.483 ENSMUST00000111941.1
ENSMUST00000052375.1
Rgs13

regulator of G-protein signaling 13

chr18_-_20682963 0.481 ENSMUST00000165229.2
Gm10269
predicted gene 10269
chr2_+_119047116 0.475 ENSMUST00000152380.1
ENSMUST00000099542.2
Casc5

cancer susceptibility candidate 5

chr10_+_99263224 0.469 ENSMUST00000020118.4
Dusp6
dual specificity phosphatase 6
chr4_+_105789869 0.468 ENSMUST00000184254.1
Gm12728
predicted gene 12728
chr17_-_37483543 0.464 ENSMUST00000016427.4
ENSMUST00000171139.2
H2-M2

histocompatibility 2, M region locus 2

chr18_+_75000469 0.463 ENSMUST00000079716.5
Rpl17
ribosomal protein L17
chr7_+_19508712 0.463 ENSMUST00000002112.8
ENSMUST00000108455.1
Trappc6a

trafficking protein particle complex 6A

chr11_+_52098681 0.462 ENSMUST00000020608.2
Ppp2ca
protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform
chr5_+_52783055 0.457 ENSMUST00000113904.2
ENSMUST00000031077.8
Zcchc4

zinc finger, CCHC domain containing 4

chr14_+_24490678 0.453 ENSMUST00000169826.1
ENSMUST00000112384.3
Rps24

ribosomal protein S24

chr11_+_94936224 0.452 ENSMUST00000001547.7
Col1a1
collagen, type I, alpha 1
chr7_-_44892358 0.443 ENSMUST00000003049.6
Med25
mediator of RNA polymerase II transcription, subunit 25 homolog (yeast)
chr9_+_119341487 0.437 ENSMUST00000175743.1
ENSMUST00000176397.1
Acaa1a

acetyl-Coenzyme A acyltransferase 1A

chr10_+_128232065 0.433 ENSMUST00000055539.4
ENSMUST00000105244.1
ENSMUST00000105243.2
ENSMUST00000125289.1
ENSMUST00000105242.1
Timeless




timeless circadian clock 1




chr5_-_62765618 0.433 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr15_+_76343504 0.431 ENSMUST00000023210.6
Cyc1
cytochrome c-1
chr2_+_112492926 0.430 ENSMUST00000003705.5
Aven
apoptosis, caspase activation inhibitor
chr2_-_130664565 0.427 ENSMUST00000089559.4
Ddrgk1
DDRGK domain containing 1
chr11_-_113684155 0.426 ENSMUST00000120194.1
Fam104a
family with sequence similarity 104, member A
chr8_-_69373914 0.424 ENSMUST00000095282.1
Gm10311
predicted gene 10311
chr6_+_49367739 0.423 ENSMUST00000060561.8
ENSMUST00000121903.1
ENSMUST00000134786.1
Fam221a


family with sequence similarity 221, member A


chr17_+_94873986 0.421 ENSMUST00000108007.4
Gm20939
predicted gene, 20939
chrX_+_56963325 0.420 ENSMUST00000096431.3
Gpr112
G protein-coupled receptor 112
chr7_-_126861828 0.418 ENSMUST00000106343.1
Ino80e
INO80 complex subunit E
chr3_-_39359128 0.404 ENSMUST00000056409.2
Gm9845
predicted pseudogene 9845
chr14_+_80000292 0.399 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr1_-_182282738 0.395 ENSMUST00000035295.5
Degs1
degenerative spermatocyte homolog 1 (Drosophila)
chr8_-_84969412 0.387 ENSMUST00000147812.1
Rnaseh2a
ribonuclease H2, large subunit
chr17_-_45599603 0.384 ENSMUST00000171847.1
ENSMUST00000166633.1
ENSMUST00000169729.1
Slc29a1


solute carrier family 29 (nucleoside transporters), member 1


chr7_+_45526330 0.377 ENSMUST00000120985.1
ENSMUST00000051810.8
Plekha4

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4

chr9_-_42399915 0.375 ENSMUST00000042190.7
Tecta
tectorin alpha
chr7_-_127895578 0.375 ENSMUST00000033074.6
Vkorc1
vitamin K epoxide reductase complex, subunit 1
chr10_-_128626464 0.374 ENSMUST00000026420.5
Rps26
ribosomal protein S26
chr8_-_120228221 0.372 ENSMUST00000183235.1
A330074K22Rik
RIKEN cDNA A330074K22 gene
chr9_-_26802563 0.371 ENSMUST00000162252.1
Glb1l2
galactosidase, beta 1-like 2
chr12_-_84617326 0.368 ENSMUST00000021666.4
Abcd4
ATP-binding cassette, sub-family D (ALD), member 4
chr11_+_58171648 0.362 ENSMUST00000020820.1
Mrpl22
mitochondrial ribosomal protein L22
chr15_+_81744848 0.354 ENSMUST00000109554.1
Zc3h7b
zinc finger CCCH type containing 7B
chr7_+_19368498 0.350 ENSMUST00000132655.1
Ppp1r13l
protein phosphatase 1, regulatory (inhibitor) subunit 13 like
chr17_-_15498263 0.350 ENSMUST00000014913.9
Psmb1
proteasome (prosome, macropain) subunit, beta type 1
chr16_+_33684460 0.346 ENSMUST00000152782.1
ENSMUST00000179453.1
Heg1

HEG homolog 1 (zebrafish)

chr9_-_42399709 0.346 ENSMUST00000160940.1
Tecta
tectorin alpha
chr2_-_170194033 0.345 ENSMUST00000180625.1
Gm17619
predicted gene, 17619
chr6_-_83121385 0.342 ENSMUST00000146328.1
ENSMUST00000113936.3
ENSMUST00000032111.4
Wbp1


WW domain binding protein 1


chr8_+_105305572 0.338 ENSMUST00000109375.2
Elmo3
engulfment and cell motility 3
chr8_-_105484350 0.337 ENSMUST00000044286.5
Zdhhc1
zinc finger, DHHC domain containing 1
chr2_-_72986716 0.336 ENSMUST00000112062.1
Gm11084
predicted gene 11084
chr15_+_78935177 0.330 ENSMUST00000145157.1
ENSMUST00000123013.1
Nol12

nucleolar protein 12

chr8_-_70527945 0.327 ENSMUST00000138260.1
ENSMUST00000117580.1
Kxd1

KxDL motif containing 1

chr2_+_155751117 0.326 ENSMUST00000029140.5
ENSMUST00000132608.1
Procr

protein C receptor, endothelial

chr12_-_4841583 0.324 ENSMUST00000020964.5
Fkbp1b
FK506 binding protein 1b
chr14_+_74735641 0.323 ENSMUST00000177283.1
Esd
esterase D/formylglutathione hydrolase
chr15_+_78934919 0.323 ENSMUST00000138880.1
ENSMUST00000149580.1
ENSMUST00000041164.3
Nol12


nucleolar protein 12



Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 8.5 GO:0043490 malate-aspartate shuttle(GO:0043490)
1.9 5.7 GO:0061075 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
1.6 4.7 GO:0006566 threonine metabolic process(GO:0006566)
0.9 2.8 GO:0071918 urea transmembrane transport(GO:0071918)
0.9 2.8 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.8 2.5 GO:0061357 Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356) positive regulation of Wnt protein secretion(GO:0061357)
0.7 2.8 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.7 2.0 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.6 1.7 GO:0006059 hexitol metabolic process(GO:0006059) alditol biosynthetic process(GO:0019401)
0.6 2.8 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.5 1.6 GO:0003104 positive regulation of glomerular filtration(GO:0003104) cell communication by chemical coupling(GO:0010643)
0.5 3.0 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.5 1.5 GO:1904956 Wnt signaling pathway involved in somitogenesis(GO:0090244) regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.4 2.7 GO:0006570 tyrosine metabolic process(GO:0006570)
0.4 3.1 GO:0019532 oxalate transport(GO:0019532)
0.4 3.5 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.4 1.9 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.4 1.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.4 2.9 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.3 1.7 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.3 2.7 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.3 1.9 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.3 0.6 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.3 1.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.3 0.8 GO:0021759 globus pallidus development(GO:0021759)
0.3 1.0 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.3 6.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.3 1.8 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.2 0.7 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.2 0.5 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.2 1.8 GO:0008343 adult feeding behavior(GO:0008343)
0.2 0.6 GO:0042701 progesterone secretion(GO:0042701)
0.2 1.1 GO:0052695 cellular glucuronidation(GO:0052695)
0.2 0.6 GO:0046110 xanthine metabolic process(GO:0046110)
0.2 0.9 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.2 2.1 GO:0097154 GABAergic neuron differentiation(GO:0097154)
0.2 0.8 GO:1990034 calcium ion export from cell(GO:1990034)
0.2 0.9 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.2 1.1 GO:0048478 replication fork protection(GO:0048478)
0.2 5.6 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.2 0.6 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.2 1.2 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.2 3.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 1.8 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.1 0.4 GO:1904975 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
0.1 0.7 GO:0060591 chondroblast differentiation(GO:0060591)
0.1 0.8 GO:0046689 response to mercury ion(GO:0046689)
0.1 0.5 GO:0060486 Clara cell differentiation(GO:0060486)
0.1 0.4 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 0.2 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.1 0.5 GO:0045113 regulation of integrin biosynthetic process(GO:0045113)
0.1 0.6 GO:0072235 distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235)
0.1 0.3 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.2 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) apoptotic process involved in heart morphogenesis(GO:0003278) glomerular mesangial cell differentiation(GO:0072008) glomerular mesangial cell development(GO:0072144) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.1 0.4 GO:0033762 response to glucagon(GO:0033762)
0.1 0.3 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 0.3 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630) positive regulation of aminoacyl-tRNA ligase activity(GO:1903632) regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.1 0.7 GO:0007343 egg activation(GO:0007343)
0.1 0.3 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.1 0.5 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.8 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.1 0.8 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.1 0.6 GO:0046549 retinal cone cell development(GO:0046549)
0.1 0.2 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.1 0.3 GO:0046294 formaldehyde catabolic process(GO:0046294)
0.1 0.2 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016) regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.1 0.9 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.7 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.1 0.5 GO:0098909 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.1 6.4 GO:0007601 visual perception(GO:0007601)
0.1 1.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.4 GO:1990564 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 0.2 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.1 0.3 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.1 0.4 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 1.0 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.1 0.7 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.1 0.4 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 0.7 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 1.4 GO:0002076 osteoblast development(GO:0002076)
0.1 0.2 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.1 0.4 GO:0015862 uridine transport(GO:0015862)
0.1 0.3 GO:0051775 response to redox state(GO:0051775)
0.1 0.3 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 0.1 GO:2001187 positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.0 0.4 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.2 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.2 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 1.4 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.2 GO:1903772 regulation of viral budding via host ESCRT complex(GO:1903772)
0.0 2.2 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.7 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.8 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.1 GO:0060467 negative regulation of fertilization(GO:0060467)
0.0 0.2 GO:0060768 epithelial cell proliferation involved in prostate gland development(GO:0060767) regulation of epithelial cell proliferation involved in prostate gland development(GO:0060768) negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 1.1 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.0 3.9 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 2.4 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.4 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.4 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013) negative regulation of T-helper 17 type immune response(GO:2000317) regulation of T-helper 17 cell differentiation(GO:2000319) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.0 1.5 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.0 0.6 GO:0008206 bile acid metabolic process(GO:0008206)
0.0 0.5 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.1 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.5 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.8 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.1 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.0 0.4 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 1.2 GO:0006284 base-excision repair(GO:0006284)
0.0 0.1 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.4 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.2 GO:0072615 interleukin-17 secretion(GO:0072615)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) connective tissue replacement(GO:0097709) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) regulation of connective tissue replacement(GO:1905203)
0.0 0.2 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.2 GO:0034982 mitochondrial protein processing(GO:0034982)
0.0 0.5 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.1 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.0 1.5 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.8 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 0.1 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.7 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.3 GO:0022904 respiratory electron transport chain(GO:0022904)
0.0 0.1 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.6 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.1 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.0 2.6 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.1 GO:1904861 excitatory synapse assembly(GO:1904861)
0.0 0.3 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 1.1 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 1.6 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.5 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.3 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.5 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 0.3 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 0.3 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 0.1 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.1 GO:1901162 serotonin biosynthetic process(GO:0042427) indole-containing compound biosynthetic process(GO:0042435) primary amino compound biosynthetic process(GO:1901162)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.0 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.5 2.0 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.4 1.7 GO:0097454 Schwann cell microvillus(GO:0097454)
0.3 1.8 GO:0005796 Golgi lumen(GO:0005796)
0.2 3.8 GO:0005614 interstitial matrix(GO:0005614)
0.2 1.4 GO:0005859 muscle myosin complex(GO:0005859)
0.2 1.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.2 1.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.2 1.1 GO:0031298 replication fork protection complex(GO:0031298)
0.2 0.5 GO:0005584 collagen type I trimer(GO:0005584)
0.1 1.6 GO:0005916 fascia adherens(GO:0005916)
0.1 0.7 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 0.5 GO:0071438 invadopodium membrane(GO:0071438)
0.1 1.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 2.7 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 0.9 GO:0071439 clathrin complex(GO:0071439)
0.1 0.6 GO:0005687 U4 snRNP(GO:0005687)
0.1 4.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.8 GO:0034709 methylosome(GO:0034709)
0.1 1.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 2.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 0.7 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 0.4 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 0.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.2 GO:0005745 m-AAA complex(GO:0005745)
0.1 0.6 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 12.0 GO:0043197 dendritic spine(GO:0043197)
0.0 0.7 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.6 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 0.5 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.5 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.4 GO:0042581 specific granule(GO:0042581)
0.0 2.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.9 GO:0070469 respiratory chain(GO:0070469)
0.0 0.7 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0000125 PCAF complex(GO:0000125)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.5 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.1 GO:0031983 vesicle lumen(GO:0031983)
0.0 0.3 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 1.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 2.0 GO:0005901 caveola(GO:0005901)
0.0 0.9 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.2 GO:0002177 manchette(GO:0002177)
0.0 0.7 GO:0016459 myosin complex(GO:0016459)
0.0 0.3 GO:0005839 proteasome core complex(GO:0005839)
0.0 1.4 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 4.0 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.1 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.2 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 1.2 GO:0043204 perikaryon(GO:0043204)
0.0 1.1 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 1.8 GO:0001650 fibrillar center(GO:0001650)
0.0 0.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 8.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
1.2 7.2 GO:0019841 retinol binding(GO:0019841)
0.7 2.0 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.6 3.6 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.5 3.8 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.4 1.7 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.4 3.0 GO:0000150 recombinase activity(GO:0000150)
0.4 5.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.4 1.6 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075) gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.4 2.4 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.4 2.8 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.3 1.7 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.3 1.3 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.3 1.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.3 3.1 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.3 1.9 GO:0001849 complement component C1q binding(GO:0001849)
0.3 2.5 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.2 2.7 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.2 0.7 GO:0070052 collagen V binding(GO:0070052)
0.2 1.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.2 1.0 GO:0015440 peptide-transporting ATPase activity(GO:0015440)
0.2 2.7 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.2 0.6 GO:0008502 melatonin receptor activity(GO:0008502)
0.2 1.3 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725)
0.2 0.5 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.2 6.3 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2 0.6 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 2.0 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.2 0.6 GO:0008410 CoA-transferase activity(GO:0008410)
0.1 1.4 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 1.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 0.7 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.4 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.1 0.1 GO:0031628 opioid receptor binding(GO:0031628)
0.1 0.9 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 1.2 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 1.0 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.3 GO:0018738 S-formylglutathione hydrolase activity(GO:0018738)
0.1 0.9 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.1 0.6 GO:0008494 translation activator activity(GO:0008494)
0.1 1.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 1.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 1.9 GO:0070628 proteasome binding(GO:0070628)
0.1 2.6 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.2 GO:0048019 receptor antagonist activity(GO:0048019)
0.1 0.5 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.4 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 2.1 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.6 GO:1990446 U1 snRNP binding(GO:1990446)
0.1 0.8 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.1 1.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.3 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1 1.1 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 1.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.9 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 0.2 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.1 0.5 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 0.5 GO:1990405 protein antigen binding(GO:1990405)
0.1 0.4 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 5.0 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 3.1 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.2 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 1.2 GO:0070064 proline-rich region binding(GO:0070064)
0.0 2.7 GO:0051287 NAD binding(GO:0051287)
0.0 0.8 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 1.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.4 GO:0048038 quinone binding(GO:0048038)
0.0 0.6 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 1.3 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 2.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.8 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 1.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.4 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 2.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 3.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.6 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.7 GO:0019843 rRNA binding(GO:0019843)
0.0 0.8 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 2.9 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.2 GO:0022842 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.0 0.3 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.7 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.1 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.4 GO:0009055 electron carrier activity(GO:0009055)
0.0 1.1 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.0 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.0 0.7 GO:0022824 transmitter-gated ion channel activity(GO:0022824) transmitter-gated channel activity(GO:0022835)
0.0 0.5 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.4 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.1 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.4 GO:0043015 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) gamma-tubulin binding(GO:0043015)
0.0 0.4 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 2.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 8.1 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.1 3.5 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.1 2.7 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.1 2.0 PID_MYC_PATHWAY C-MYC pathway
0.1 2.9 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 1.9 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 2.0 PID_ALK1_PATHWAY ALK1 signaling events
0.0 1.4 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 2.1 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 0.7 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 1.4 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.4 PID_BMP_PATHWAY BMP receptor signaling
0.0 4.8 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.3 PID_ATR_PATHWAY ATR signaling pathway
0.0 0.7 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.7 PID_IGF1_PATHWAY IGF1 pathway
0.0 0.6 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.9 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 0.7 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.5 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 0.1 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 0.5 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 0.8 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.7 PID_E2F_PATHWAY E2F transcription factor network
0.0 0.8 PID_P73PATHWAY p73 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.8 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.2 3.1 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 3.0 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 1.2 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 2.0 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 7.6 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 1.6 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.1 0.9 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 2.7 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 6.8 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 0.8 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 3.9 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 3.8 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 0.6 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.1 2.5 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 0.9 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.1 1.1 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 1.4 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.1 0.6 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.9 REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.7 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.4 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.7 REACTOME_GAP_JUNCTION_TRAFFICKING Genes involved in Gap junction trafficking
0.0 0.6 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.7 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 0.5 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 2.3 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 1.3 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 3.4 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.0 1.8 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.2 REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.6 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.5 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.7 REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.5 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 2.6 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.5 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.9 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.1 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 0.1 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.1 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.1 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.3 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.7 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.4 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules