Motif ID: Scrt1

Z-value: 1.756


Transcription factors associated with Scrt1:

Gene SymbolEntrez IDGene Name
Scrt1 ENSMUSG00000048385.8 Scrt1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Scrt1mm10_v2_chr15_-_76521902_76522129-0.681.0e-06Click!


Activity profile for motif Scrt1.

activity profile for motif Scrt1


Sorted Z-values histogram for motif Scrt1

Sorted Z-values for motif Scrt1



Network of associatons between targets according to the STRING database.



First level regulatory network of Scrt1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_30973367 18.012 ENSMUST00000108116.3
Lsr
lipolysis stimulated lipoprotein receptor
chr15_-_98004634 15.988 ENSMUST00000131560.1
ENSMUST00000088355.5
Col2a1

collagen, type II, alpha 1

chr3_+_34649987 14.764 ENSMUST00000099151.2
Sox2
SRY-box containing gene 2
chr7_-_30973399 14.129 ENSMUST00000098553.4
ENSMUST00000147431.1
Lsr

lipolysis stimulated lipoprotein receptor

chr11_-_55419898 13.925 ENSMUST00000108858.1
ENSMUST00000141530.1
Sparc

secreted acidic cysteine rich glycoprotein

chr10_+_56377300 13.365 ENSMUST00000068581.7
Gja1
gap junction protein, alpha 1
chr7_-_30973464 12.712 ENSMUST00000001279.8
Lsr
lipolysis stimulated lipoprotein receptor
chr2_+_31950257 12.429 ENSMUST00000001920.7
Aif1l
allograft inflammatory factor 1-like
chr2_+_131234043 11.410 ENSMUST00000041362.5
ENSMUST00000110199.2
Mavs

mitochondrial antiviral signaling protein

chr17_-_25570678 11.135 ENSMUST00000025003.3
ENSMUST00000173447.1
Sox8

SRY-box containing gene 8

chr1_-_165194310 9.455 ENSMUST00000043338.4
Sft2d2
SFT2 domain containing 2
chr7_+_110221697 9.296 ENSMUST00000033325.7
Swap70
SWA-70 protein
chr11_+_115163333 9.279 ENSMUST00000021077.3
Slc9a3r1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr7_-_144939823 8.779 ENSMUST00000093962.4
Ccnd1
cyclin D1
chr12_-_91779129 8.655 ENSMUST00000170077.1
Ston2
stonin 2
chr7_-_25250720 8.535 ENSMUST00000116343.2
ENSMUST00000045847.8
Erf

Ets2 repressor factor

chr13_-_81633119 8.364 ENSMUST00000126444.1
ENSMUST00000128585.1
ENSMUST00000146749.1
ENSMUST00000095585.4
Gpr98



G protein-coupled receptor 98



chr14_-_70642268 8.302 ENSMUST00000022697.5
Fgf17
fibroblast growth factor 17
chr5_+_33658567 8.144 ENSMUST00000114426.3
Tacc3
transforming, acidic coiled-coil containing protein 3
chrX_+_100730178 8.018 ENSMUST00000113744.1
Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr6_+_128375456 7.769 ENSMUST00000100926.2
4933413G19Rik
RIKEN cDNA 4933413G19 gene
chr5_+_33658550 6.984 ENSMUST00000152847.1
Tacc3
transforming, acidic coiled-coil containing protein 3
chr3_-_20155069 6.900 ENSMUST00000184552.1
ENSMUST00000178328.1
Gyg

glycogenin

chrX_-_72274747 6.743 ENSMUST00000064780.3
Gabre
gamma-aminobutyric acid (GABA) A receptor, subunit epsilon
chr8_+_31187317 6.583 ENSMUST00000066173.5
ENSMUST00000161788.1
ENSMUST00000110527.2
ENSMUST00000161502.1
Fut10



fucosyltransferase 10



chr9_-_27155418 6.321 ENSMUST00000167074.1
ENSMUST00000034472.8
Jam3

junction adhesion molecule 3

chr5_+_33658123 6.187 ENSMUST00000074849.6
ENSMUST00000079534.4
Tacc3

transforming, acidic coiled-coil containing protein 3

chr12_-_119238794 6.067 ENSMUST00000026360.8
Itgb8
integrin beta 8
chr3_+_81036360 5.789 ENSMUST00000029652.3
Pdgfc
platelet-derived growth factor, C polypeptide
chr1_-_153549697 5.784 ENSMUST00000041874.7
Npl
N-acetylneuraminate pyruvate lyase
chr18_+_48045329 5.503 ENSMUST00000076155.4
Gm5506
predicted gene 5506
chr5_-_137116177 5.468 ENSMUST00000054384.5
ENSMUST00000152207.1
Trim56

tripartite motif-containing 56

chr13_+_99100698 5.426 ENSMUST00000181742.1
Gm807
predicted gene 807
chr1_+_131867224 5.308 ENSMUST00000112386.1
ENSMUST00000027693.7
Rab7l1

RAB7, member RAS oncogene family-like 1

chr4_+_111719975 5.205 ENSMUST00000038868.7
ENSMUST00000070513.6
ENSMUST00000153746.1
Spata6


spermatogenesis associated 6


chr3_-_108840477 5.138 ENSMUST00000106596.3
ENSMUST00000102621.4
Stxbp3a

syntaxin binding protein 3A

chr12_-_40038025 5.076 ENSMUST00000101472.3
Arl4a
ADP-ribosylation factor-like 4A
chr4_-_116123618 4.931 ENSMUST00000102704.3
ENSMUST00000102705.3
Rad54l

RAD54 like (S. cerevisiae)

chr14_+_60634719 4.904 ENSMUST00000022566.7
ENSMUST00000159729.1
Spata13

spermatogenesis associated 13

chr6_-_88898664 4.900 ENSMUST00000058011.6
Mcm2
minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
chr18_+_56432116 4.818 ENSMUST00000070166.5
Gramd3
GRAM domain containing 3
chr13_+_23756937 4.744 ENSMUST00000102965.2
Hist1h4b
histone cluster 1, H4b
chr7_-_44815658 4.644 ENSMUST00000107893.1
Atf5
activating transcription factor 5
chr11_+_53770458 4.616 ENSMUST00000138913.1
ENSMUST00000123376.1
ENSMUST00000019043.6
ENSMUST00000133291.1
Irf1



interferon regulatory factor 1



chr16_+_16213318 4.600 ENSMUST00000162150.1
ENSMUST00000161342.1
ENSMUST00000039408.2
Pkp2


plakophilin 2


chr9_+_65214690 4.545 ENSMUST00000069000.7
Parp16
poly (ADP-ribose) polymerase family, member 16
chr11_-_100355383 4.475 ENSMUST00000146878.2
Hap1
huntingtin-associated protein 1
chr4_+_98923845 4.412 ENSMUST00000091358.4
Usp1
ubiquitin specific peptidase 1
chr6_-_53820764 4.363 ENSMUST00000127748.2
Tril
TLR4 interactor with leucine-rich repeats
chr4_-_129189646 4.305 ENSMUST00000106059.1
S100pbp
S100P binding protein
chr4_+_111720187 4.234 ENSMUST00000084354.3
Spata6
spermatogenesis associated 6
chr6_-_124779686 4.209 ENSMUST00000147669.1
ENSMUST00000128697.1
ENSMUST00000032218.3
ENSMUST00000112475.2
Lrrc23



leucine rich repeat containing 23



chr3_-_67375163 4.117 ENSMUST00000166353.1
Gm17402
predicted gene, 17402
chr5_-_138171248 4.063 ENSMUST00000153867.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr4_-_129189512 3.926 ENSMUST00000117965.1
ENSMUST00000106061.2
ENSMUST00000072431.6
S100pbp


S100P binding protein


chr17_+_26917091 3.886 ENSMUST00000078961.4
Kifc5b
kinesin family member C5B
chr15_+_34306666 3.759 ENSMUST00000163455.2
ENSMUST00000022947.5
Matn2

matrilin 2

chr6_+_138140521 3.676 ENSMUST00000120939.1
ENSMUST00000120302.1
Mgst1

microsomal glutathione S-transferase 1

chr5_-_125294107 3.656 ENSMUST00000127148.1
Scarb1
scavenger receptor class B, member 1
chr4_-_129189600 3.581 ENSMUST00000117497.1
ENSMUST00000117350.1
S100pbp

S100P binding protein

chr6_-_23839137 3.529 ENSMUST00000166458.2
ENSMUST00000142913.2
ENSMUST00000115357.1
ENSMUST00000069074.7
ENSMUST00000115361.2
ENSMUST00000018122.7
ENSMUST00000115355.1
ENSMUST00000115356.2
Cadps2







Ca2+-dependent activator protein for secretion 2







chr18_-_78123324 3.489 ENSMUST00000160292.1
ENSMUST00000091813.5
Slc14a1

solute carrier family 14 (urea transporter), member 1

chr2_-_127788854 3.471 ENSMUST00000028857.7
ENSMUST00000110357.1
Nphp1

nephronophthisis 1 (juvenile) homolog (human)

chr6_-_120357422 3.454 ENSMUST00000032283.5
Ccdc77
coiled-coil domain containing 77
chr13_-_76098606 3.438 ENSMUST00000120573.1
Arsk
arylsulfatase K
chr2_-_163750169 3.392 ENSMUST00000017841.3
Ada
adenosine deaminase
chr2_+_25218741 3.352 ENSMUST00000028346.3
Fam166a
family with sequence similarity 166, member A
chr16_+_44347121 3.336 ENSMUST00000050897.6
Spice1
spindle and centriole associated protein 1
chr15_+_80948484 3.272 ENSMUST00000023043.2
ENSMUST00000168756.1
ENSMUST00000164806.1
Adsl


adenylosuccinate lyase


chr9_+_59656368 3.262 ENSMUST00000034834.9
ENSMUST00000163694.2
Pkm

pyruvate kinase, muscle

chr2_+_72285637 3.254 ENSMUST00000090824.5
ENSMUST00000135469.1
Zak

sterile alpha motif and leucine zipper containing kinase AZK

chr4_-_151044564 3.229 ENSMUST00000103204.4
Per3
period circadian clock 3
chr16_-_10313940 3.140 ENSMUST00000078357.4
Emp2
epithelial membrane protein 2
chr11_+_71749914 3.107 ENSMUST00000150531.1
Wscd1
WSC domain containing 1
chr13_+_22043189 3.105 ENSMUST00000110452.1
Hist1h2bj
histone cluster 1, H2bj
chr6_-_90716489 3.073 ENSMUST00000101153.3
Iqsec1
IQ motif and Sec7 domain 1
chr12_-_40037387 3.029 ENSMUST00000146905.1
Arl4a
ADP-ribosylation factor-like 4A
chr12_+_113098199 2.985 ENSMUST00000009099.6
ENSMUST00000109723.1
ENSMUST00000109726.1
ENSMUST00000109727.2
ENSMUST00000069690.4
Mta1




metastasis associated 1




chr9_+_91368970 2.905 ENSMUST00000172646.1
Zic4
zinc finger protein of the cerebellum 4
chr2_+_150909565 2.833 ENSMUST00000028948.4
Gins1
GINS complex subunit 1 (Psf1 homolog)
chr6_-_120357342 2.822 ENSMUST00000163827.1
Ccdc77
coiled-coil domain containing 77
chr6_-_120357440 2.811 ENSMUST00000112703.1
Ccdc77
coiled-coil domain containing 77
chr5_-_33629577 2.799 ENSMUST00000153696.1
ENSMUST00000045329.3
ENSMUST00000065119.8
Fam53a


family with sequence similarity 53, member A


chr13_+_23934434 2.752 ENSMUST00000072391.1
Hist1h2aa
histone cluster 1, H2aa
chr13_-_23991158 2.739 ENSMUST00000021770.7
Scgn
secretagogin, EF-hand calcium binding protein
chr9_+_91368811 2.710 ENSMUST00000173054.1
Zic4
zinc finger protein of the cerebellum 4
chr11_-_119355484 2.651 ENSMUST00000100172.2
ENSMUST00000005173.4
Sgsh

N-sulfoglucosamine sulfohydrolase (sulfamidase)

chr3_-_133091764 2.647 ENSMUST00000029651.4
Gstcd
glutathione S-transferase, C-terminal domain containing
chr9_-_121857952 2.644 ENSMUST00000060251.6
Higd1a
HIG1 domain family, member 1A
chr11_+_68968107 2.638 ENSMUST00000102606.3
ENSMUST00000018884.5
Slc25a35

solute carrier family 25, member 35

chr13_-_22042949 2.608 ENSMUST00000091741.4
Hist1h2ag
histone cluster 1, H2ag
chr12_+_3572379 2.466 ENSMUST00000173199.1
ENSMUST00000164578.2
ENSMUST00000174479.1
ENSMUST00000173240.1
ENSMUST00000174663.1
ENSMUST00000173736.1
Dtnb





dystrobrevin, beta





chr19_+_6364557 2.450 ENSMUST00000155973.1
Sf1
splicing factor 1
chr5_+_136116631 2.444 ENSMUST00000111127.1
ENSMUST00000041366.7
ENSMUST00000111129.1
Polr2j


polymerase (RNA) II (DNA directed) polypeptide J


chr19_-_5388656 2.423 ENSMUST00000044207.4
Sart1
squamous cell carcinoma antigen recognized by T cells 1
chr3_-_133092029 2.396 ENSMUST00000080583.5
Gstcd
glutathione S-transferase, C-terminal domain containing
chr11_+_102881204 2.364 ENSMUST00000021307.3
ENSMUST00000159834.1
Ccdc103

coiled-coil domain containing 103

chr11_+_120491840 2.360 ENSMUST00000026899.3
Slc25a10
solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10
chr12_+_3572528 2.341 ENSMUST00000173998.1
Dtnb
dystrobrevin, beta
chr10_-_81266906 2.312 ENSMUST00000046114.4
Mrpl54
mitochondrial ribosomal protein L54
chr1_+_160195215 2.230 ENSMUST00000135680.1
ENSMUST00000097193.2
Mrps14

mitochondrial ribosomal protein S14

chr11_-_6444352 2.213 ENSMUST00000093346.5
ENSMUST00000109737.2
H2afv

H2A histone family, member V

chr18_-_14682756 2.131 ENSMUST00000040964.6
ENSMUST00000092041.3
ENSMUST00000040924.7
Ss18


synovial sarcoma translocation, Chromosome 18


chr7_-_133776681 2.111 ENSMUST00000130182.1
ENSMUST00000106139.1
Dhx32

DEAH (Asp-Glu-Ala-His) box polypeptide 32

chr7_-_133776772 2.092 ENSMUST00000033290.5
Dhx32
DEAH (Asp-Glu-Ala-His) box polypeptide 32
chr17_-_14961273 2.090 ENSMUST00000024657.5
Phf10
PHD finger protein 10
chr19_-_10880370 2.053 ENSMUST00000133303.1
Tmem109
transmembrane protein 109
chr11_-_102880981 2.048 ENSMUST00000107060.1
Eftud2
elongation factor Tu GTP binding domain containing 2
chr6_+_107529717 2.040 ENSMUST00000049285.8
Lrrn1
leucine rich repeat protein 1, neuronal
chr5_-_138171216 1.997 ENSMUST00000147920.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr18_+_24205303 1.979 ENSMUST00000000430.7
Galnt1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1
chr11_-_102880925 1.922 ENSMUST00000021306.7
Eftud2
elongation factor Tu GTP binding domain containing 2
chr5_+_137630116 1.900 ENSMUST00000175968.1
Lrch4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr4_+_98923908 1.871 ENSMUST00000169053.1
Usp1
ubiquitin specific peptidase 1
chr18_+_24205722 1.822 ENSMUST00000170243.1
Galnt1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1
chr7_-_65370908 1.775 ENSMUST00000032729.6
Tjp1
tight junction protein 1
chr2_-_39005574 1.769 ENSMUST00000080861.5
Rpl35
ribosomal protein L35
chrX_-_104671048 1.727 ENSMUST00000042070.5
Zdhhc15
zinc finger, DHHC domain containing 15
chr8_+_71488103 1.653 ENSMUST00000007754.6
ENSMUST00000168847.1
Gtpbp3

GTP binding protein 3

chr9_-_31131817 1.635 ENSMUST00000034478.2
St14
suppression of tumorigenicity 14 (colon carcinoma)
chr2_-_92370968 1.579 ENSMUST00000176774.1
Gyltl1b
glycosyltransferase-like 1B
chr2_-_30093642 1.548 ENSMUST00000102865.4
Zdhhc12
zinc finger, DHHC domain containing 12
chr10_-_75932468 1.544 ENSMUST00000120281.1
ENSMUST00000000924.6
Mmp11

matrix metallopeptidase 11

chr7_-_133782721 1.542 ENSMUST00000063669.1
Dhx32
DEAH (Asp-Glu-Ala-His) box polypeptide 32
chr1_-_87156127 1.537 ENSMUST00000160810.1
Ecel1
endothelin converting enzyme-like 1
chr8_-_122611419 1.533 ENSMUST00000015171.9
Galns
galactosamine (N-acetyl)-6-sulfate sulfatase
chr19_-_24861828 1.522 ENSMUST00000047666.4
Pgm5
phosphoglucomutase 5
chr6_+_146888481 1.430 ENSMUST00000016631.7
ENSMUST00000111623.2
Ppfibp1

PTPRF interacting protein, binding protein 1 (liprin beta 1)

chr14_+_54883377 1.409 ENSMUST00000022806.3
ENSMUST00000172844.1
ENSMUST00000133397.2
ENSMUST00000134077.1
Bcl2l2


Gm20521
BCL2-like 2


predicted gene 20521
chr11_-_12464881 1.403 ENSMUST00000046755.7
ENSMUST00000109651.2
Cobl

cordon-bleu WH2 repeat

chr2_-_30093607 1.367 ENSMUST00000081838.6
Zdhhc12
zinc finger, DHHC domain containing 12
chr8_+_127064107 1.361 ENSMUST00000162536.1
ENSMUST00000026921.6
ENSMUST00000162665.1
ENSMUST00000160766.1
ENSMUST00000162602.1
ENSMUST00000162531.1
ENSMUST00000160581.1
ENSMUST00000161355.1
ENSMUST00000159537.1
Pard3








par-3 (partitioning defective 3) homolog (C. elegans)








chr4_+_109676568 1.344 ENSMUST00000102724.4
Faf1
Fas-associated factor 1
chr5_+_146832890 1.335 ENSMUST00000035983.5
Rpl21
ribosomal protein L21
chr2_-_5862923 1.332 ENSMUST00000071016.2
Gm13199
predicted gene 13199
chr17_-_25844417 1.302 ENSMUST00000176591.1
Rhot2
ras homolog gene family, member T2
chr10_+_13499534 1.293 ENSMUST00000130865.1
ENSMUST00000120549.1
Fuca2

fucosidase, alpha-L- 2, plasma

chr7_-_19399859 1.286 ENSMUST00000047170.3
ENSMUST00000108459.2
Klc3

kinesin light chain 3

chr9_-_22117123 1.249 ENSMUST00000013966.6
Elof1
elongation factor 1 homolog (ELF1, S. cerevisiae)
chr2_+_119034783 1.237 ENSMUST00000028796.1
Rpusd2
RNA pseudouridylate synthase domain containing 2
chr6_-_33060256 1.232 ENSMUST00000066379.4
Chchd3
coiled-coil-helix-coiled-coil-helix domain containing 3
chr2_-_170142673 1.206 ENSMUST00000109155.1
Zfp217
zinc finger protein 217
chr19_-_5912771 1.199 ENSMUST00000118623.1
Dpf2
D4, zinc and double PHD fingers family 2
chr9_+_97179153 1.186 ENSMUST00000177657.1
Rpl7a-ps10
ribosomal protein L7A, pseudogene 10
chr4_-_93335510 1.179 ENSMUST00000066774.4
Tusc1
tumor suppressor candidate 1
chr7_+_44816088 1.175 ENSMUST00000057195.9
ENSMUST00000107891.1
Nup62

nucleoporin 62

chr12_-_17011727 1.138 ENSMUST00000095823.2
2410004P03Rik
RIKEN cDNA 2410004P03 gene
chr2_-_168590191 1.075 ENSMUST00000029057.6
ENSMUST00000074618.3
Nfatc2

nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2

chr19_-_5912834 1.074 ENSMUST00000136983.1
Dpf2
D4, zinc and double PHD fingers family 2
chr7_+_141447645 1.060 ENSMUST00000106004.1
ENSMUST00000106003.1
Rplp2

ribosomal protein, large P2

chr1_+_88227005 1.041 ENSMUST00000061013.6
ENSMUST00000113130.1
Mroh2a

maestro heat-like repeat family member 2A

chr15_-_101054399 1.040 ENSMUST00000178140.1
Fignl2
fidgetin-like 2
chr3_-_95687846 1.023 ENSMUST00000015994.3
ENSMUST00000148854.1
ENSMUST00000117782.1
Adamtsl4


ADAMTS-like 4


chr12_-_69681795 1.013 ENSMUST00000183277.1
ENSMUST00000035773.7
Sos2

son of sevenless homolog 2 (Drosophila)

chr15_-_80264276 0.936 ENSMUST00000052499.7
Rps19bp1
ribosomal protein S19 binding protein 1
chr17_+_28272191 0.929 ENSMUST00000169040.1
Ppard
peroxisome proliferator activator receptor delta
chr17_-_25844514 0.925 ENSMUST00000176709.1
Rhot2
ras homolog gene family, member T2
chr1_+_75521521 0.906 ENSMUST00000027414.9
ENSMUST00000113553.1
Stk11ip

serine/threonine kinase 11 interacting protein

chr11_+_101316200 0.896 ENSMUST00000142640.1
ENSMUST00000019470.7
Psme3

proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)

chr2_+_92915080 0.833 ENSMUST00000028648.2
Syt13
synaptotagmin XIII
chr18_-_7004717 0.829 ENSMUST00000079788.4
Mkx
mohawk homeobox
chr3_+_4211716 0.804 ENSMUST00000170943.1
Gm8775
predicted gene 8775
chr7_+_140763739 0.800 ENSMUST00000026552.7
Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
chr14_+_8080315 0.797 ENSMUST00000023924.3
Rpp14
ribonuclease P 14 subunit
chr11_-_115187827 0.780 ENSMUST00000103041.1
Nat9
N-acetyltransferase 9 (GCN5-related, putative)
chr16_+_31663935 0.777 ENSMUST00000100001.3
ENSMUST00000064477.7
Dlg1

discs, large homolog 1 (Drosophila)

chr6_-_148831448 0.771 ENSMUST00000048418.7
Ipo8
importin 8
chr6_+_21985903 0.749 ENSMUST00000137437.1
ENSMUST00000115383.2
Cped1

cadherin-like and PC-esterase domain containing 1

chr3_+_121426495 0.744 ENSMUST00000029773.8
Cnn3
calponin 3, acidic
chr2_-_168590315 0.742 ENSMUST00000109184.1
Nfatc2
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2
chr19_+_6335093 0.739 ENSMUST00000078137.5
Men1
multiple endocrine neoplasia 1
chr1_-_160077918 0.675 ENSMUST00000028061.3
4930562F07Rik
RIKEN cDNA 4930562F07 gene
chr17_-_56183887 0.651 ENSMUST00000019723.7
D17Wsu104e
DNA segment, Chr 17, Wayne State University 104, expressed
chr5_-_138171813 0.651 ENSMUST00000155902.1
ENSMUST00000148879.1
Mcm7

minichromosome maintenance deficient 7 (S. cerevisiae)

chr1_+_172482199 0.625 ENSMUST00000135267.1
ENSMUST00000052629.6
ENSMUST00000111235.2
Igsf9


immunoglobulin superfamily, member 9


chr2_-_32260138 0.619 ENSMUST00000002625.8
Uck1
uridine-cytidine kinase 1
chr14_+_26579535 0.599 ENSMUST00000037585.7
Dennd6a
DENN/MADD domain containing 6A
chr10_-_107123585 0.584 ENSMUST00000165067.1
ENSMUST00000044668.4
Acss3

acyl-CoA synthetase short-chain family member 3

chr6_-_33060172 0.575 ENSMUST00000115091.1
ENSMUST00000127666.1
Chchd3

coiled-coil-helix-coiled-coil-helix domain containing 3

chr15_+_76671615 0.530 ENSMUST00000037551.8
Ppp1r16a
protein phosphatase 1, regulatory (inhibitor) subunit 16A
chr9_+_94669876 0.490 ENSMUST00000033463.9
Slc9a9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr5_-_34637107 0.483 ENSMUST00000124668.1
ENSMUST00000001109.4
ENSMUST00000155577.1
ENSMUST00000114329.1
Mfsd10



major facilitator superfamily domain containing 10



chrX_-_133981765 0.483 ENSMUST00000113297.2
ENSMUST00000174542.1
ENSMUST00000033608.8
ENSMUST00000113294.1
Sytl4



synaptotagmin-like 4



chrX_-_152769461 0.444 ENSMUST00000101141.2
ENSMUST00000062317.4
Shroom2

shroom family member 2

chr18_-_3281036 0.438 ENSMUST00000049942.6
ENSMUST00000139537.1
ENSMUST00000124747.1
Crem


cAMP responsive element modulator


chr3_+_90537306 0.426 ENSMUST00000107335.1
S100a16
S100 calcium binding protein A16
chr3_+_88325023 0.425 ENSMUST00000177005.1
0610031J06Rik
RIKEN cDNA 0610031J06 gene
chr3_+_90537242 0.423 ENSMUST00000098911.3
S100a16
S100 calcium binding protein A16
chr11_-_62539257 0.388 ENSMUST00000018653.1
Cenpv
centromere protein V
chr3_+_90600203 0.369 ENSMUST00000001047.7
S100a3
S100 calcium binding protein A3
chr6_+_88084473 0.360 ENSMUST00000032143.6
Rpn1
ribophorin I
chr10_+_116301374 0.356 ENSMUST00000092167.5
Ptprb
protein tyrosine phosphatase, receptor type, B
chr5_-_34637203 0.319 ENSMUST00000114331.3
Mfsd10
major facilitator superfamily domain containing 10
chr19_+_6334979 0.293 ENSMUST00000113504.3
ENSMUST00000113502.3
ENSMUST00000079327.5
ENSMUST00000056391.8
ENSMUST00000113501.1
ENSMUST00000113500.1
ENSMUST00000166909.1
Men1






multiple endocrine neoplasia 1






chr8_-_119558718 0.290 ENSMUST00000081381.4
ENSMUST00000098362.3
Mbtps1

membrane-bound transcription factor peptidase, site 1

chr3_+_133091840 0.284 ENSMUST00000029650.8
Ints12
integrator complex subunit 12
chr3_-_90433603 0.282 ENSMUST00000029542.5
ENSMUST00000071488.3
Ints3

integrator complex subunit 3

chr9_+_110333402 0.279 ENSMUST00000133114.1
ENSMUST00000125759.1
Scap

SREBF chaperone

chr2_-_28583189 0.278 ENSMUST00000113889.2
Gtf3c5
general transcription factor IIIC, polypeptide 5
chr3_-_89101907 0.276 ENSMUST00000081848.8
Fdps
farnesyl diphosphate synthetase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
15.0 44.9 GO:1904274 tricellular tight junction assembly(GO:1904274)
4.5 13.4 GO:0003104 positive regulation of glomerular filtration(GO:0003104) cell communication by chemical coupling(GO:0010643)
3.8 11.4 GO:0071649 regulation of chemokine (C-C motif) ligand 5 production(GO:0071649)
3.7 11.1 GO:0072034 renal vesicle induction(GO:0072034)
3.1 9.3 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
2.1 12.7 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
2.1 14.8 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
1.7 8.5 GO:0010668 ectodermal cell differentiation(GO:0010668)
1.5 4.6 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) negative regulation of regulatory T cell differentiation(GO:0045590) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
1.5 4.6 GO:0002159 desmosome assembly(GO:0002159) adherens junction maintenance(GO:0034334) intermediate filament bundle assembly(GO:0045110) maintenance of organ identity(GO:0048496)
1.5 16.0 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
1.4 5.8 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
1.3 22.1 GO:0030953 astral microtubule organization(GO:0030953)
1.3 8.8 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
1.2 3.7 GO:0015920 regulation of phosphatidylcholine catabolic process(GO:0010899) lipopolysaccharide transport(GO:0015920)
1.2 3.5 GO:0071918 urea transmembrane transport(GO:0071918)
1.2 11.6 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
1.2 3.5 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
1.1 4.5 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
1.1 3.3 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
1.0 3.0 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.9 3.7 GO:0006982 response to lipid hydroperoxide(GO:0006982) cellular response to lipid hydroperoxide(GO:0071449)
0.9 4.5 GO:0032901 positive regulation of neurotrophin production(GO:0032901)
0.9 2.7 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.8 5.8 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.8 8.0 GO:0090527 actin filament reorganization(GO:0090527)
0.8 3.8 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.7 6.3 GO:0002318 myeloid progenitor cell differentiation(GO:0002318) leukocyte migration involved in inflammatory response(GO:0002523)
0.6 2.4 GO:0015744 succinate transport(GO:0015744)
0.6 6.3 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.5 1.6 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.5 3.3 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.5 3.5 GO:1990504 dense core granule exocytosis(GO:1990504)
0.5 1.4 GO:0001757 somite specification(GO:0001757)
0.4 3.1 GO:0003093 regulation of glomerular filtration(GO:0003093)
0.4 0.8 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.4 2.4 GO:0045583 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.4 1.2 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.4 6.1 GO:0001573 ganglioside metabolic process(GO:0001573)
0.4 13.9 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.3 2.4 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.3 4.1 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.3 8.7 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.3 5.5 GO:0046597 negative regulation of viral entry into host cell(GO:0046597) negative regulation of viral release from host cell(GO:1902187)
0.3 3.2 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.3 2.8 GO:1902969 mitotic DNA replication(GO:1902969)
0.2 4.7 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.2 6.7 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.2 1.4 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.2 0.9 GO:0006776 vitamin A metabolic process(GO:0006776)
0.2 1.4 GO:0003383 apical constriction(GO:0003383)
0.2 1.3 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.2 8.1 GO:0050873 brown fat cell differentiation(GO:0050873)
0.2 2.4 GO:0030238 male sex determination(GO:0030238)
0.2 4.4 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.2 3.1 GO:0044458 motile cilium assembly(GO:0044458)
0.2 1.0 GO:0002051 osteoblast fate commitment(GO:0002051)
0.2 1.0 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.2 1.8 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.2 1.3 GO:0035635 fucose metabolic process(GO:0006004) entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.2 1.8 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.2 0.8 GO:0042891 antibiotic transport(GO:0042891)
0.2 4.6 GO:0018345 protein palmitoylation(GO:0018345)
0.1 0.6 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.1 1.8 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 2.6 GO:0046599 regulation of centriole replication(GO:0046599)
0.1 3.7 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 2.6 GO:0090201 negative regulation of release of cytochrome c from mitochondria(GO:0090201)
0.1 0.6 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.1 1.2 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.1 8.3 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.1 3.1 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 1.8 GO:0042407 cristae formation(GO:0042407)
0.1 6.9 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 0.5 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.7 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 1.5 GO:0030574 collagen catabolic process(GO:0030574)
0.1 0.3 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.1 2.2 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.1 1.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.4 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.1 3.8 GO:0048678 response to axon injury(GO:0048678)
0.1 2.1 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.1 7.4 GO:0006342 chromatin silencing(GO:0006342)
0.1 0.8 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 4.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 0.5 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 1.5 GO:0003016 respiratory system process(GO:0003016)
0.0 0.8 GO:0019369 drug metabolic process(GO:0017144) arachidonic acid metabolic process(GO:0019369)
0.0 0.4 GO:0045176 apical protein localization(GO:0045176)
0.0 0.3 GO:0061051 terpenoid biosynthetic process(GO:0016114) positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.0 1.0 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 1.8 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 2.0 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.3 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.6 GO:0016180 snRNA processing(GO:0016180)
0.0 1.7 GO:0006400 tRNA modification(GO:0006400)
0.0 0.1 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 1.1 GO:0006414 translational elongation(GO:0006414)
0.0 8.2 GO:0008380 RNA splicing(GO:0008380)
0.0 0.1 GO:0035026 leading edge cell differentiation(GO:0035026)
0.0 3.1 GO:1902593 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 0.1 GO:0042472 inner ear morphogenesis(GO:0042472)
0.0 0.1 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.3 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 0.0 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
7.5 44.9 GO:0061689 tricellular tight junction(GO:0061689)
3.5 13.9 GO:0031092 platelet alpha granule membrane(GO:0031092)
1.3 16.0 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
1.3 6.3 GO:0033010 paranodal junction(GO:0033010)
1.2 13.4 GO:0005916 fascia adherens(GO:0005916)
1.0 2.1 GO:0071564 npBAF complex(GO:0071564)
0.9 2.8 GO:0000811 GINS complex(GO:0000811)
0.8 9.3 GO:0032426 stereocilium tip(GO:0032426)
0.8 11.6 GO:0042555 MCM complex(GO:0042555)
0.7 4.4 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.4 4.6 GO:0030057 desmosome(GO:0030057)
0.3 3.7 GO:0031528 microvillus membrane(GO:0031528)
0.3 1.4 GO:1990357 terminal web(GO:1990357)
0.3 6.1 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.2 6.4 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.2 0.9 GO:0008537 proteasome activator complex(GO:0008537)
0.2 1.8 GO:0046581 intercellular canaliculus(GO:0046581)
0.2 1.8 GO:0061617 MICOS complex(GO:0061617)
0.2 15.1 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.2 4.5 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.2 2.1 GO:0043219 lateral loop(GO:0043219)
0.2 1.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.2 8.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 1.2 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 4.7 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 2.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 26.2 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.1 1.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 19.4 GO:0005884 actin filament(GO:0005884)
0.1 3.0 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 6.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 3.5 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 3.4 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 5.2 GO:0005871 kinesin complex(GO:0005871)
0.1 2.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 7.8 GO:0005814 centriole(GO:0005814)
0.1 0.2 GO:0005581 collagen trimer(GO:0005581)
0.1 0.8 GO:0030677 ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.1 2.2 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 1.0 GO:0005614 interstitial matrix(GO:0005614)
0.1 12.2 GO:0008021 synaptic vesicle(GO:0008021)
0.1 2.2 GO:0000786 nucleosome(GO:0000786)
0.1 0.3 GO:0070876 SOSS complex(GO:0070876)
0.1 4.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 22.6 GO:0005813 centrosome(GO:0005813)
0.0 3.7 GO:0005604 basement membrane(GO:0005604)
0.0 4.8 GO:0031514 motile cilium(GO:0031514)
0.0 2.3 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.5 GO:0043034 costamere(GO:0043034)
0.0 0.5 GO:0070382 exocytic vesicle(GO:0070382)
0.0 10.0 GO:0016607 nuclear speck(GO:0016607)
0.0 1.2 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 6.5 GO:0005681 spliceosomal complex(GO:0005681)
0.0 2.1 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 2.6 GO:0070469 respiratory chain(GO:0070469)
0.0 0.4 GO:0051233 spindle midzone(GO:0051233)
0.0 1.0 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 1.9 GO:0016605 PML body(GO:0016605)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 1.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 4.9 GO:0000790 nuclear chromatin(GO:0000790)
0.0 5.2 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.8 GO:0031526 brush border membrane(GO:0031526)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.7 GO:0005913 cell-cell adherens junction(GO:0005913)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 13.4 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075) gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
3.2 16.0 GO:0042289 MHC class II protein binding(GO:0042289)
2.9 48.5 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
2.8 8.3 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
2.3 11.4 GO:0050700 CARD domain binding(GO:0050700)
1.9 9.4 GO:0032027 myosin light chain binding(GO:0032027)
1.6 6.6 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
1.4 5.8 GO:0016833 oxo-acid-lyase activity(GO:0016833)
1.1 3.3 GO:0004743 pyruvate kinase activity(GO:0004743)
1.0 8.0 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.9 6.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.8 3.3 GO:0016842 amidine-lyase activity(GO:0016842)
0.8 2.4 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.8 6.9 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.8 14.4 GO:0035198 miRNA binding(GO:0035198)
0.7 9.3 GO:0017081 chloride channel regulator activity(GO:0017081)
0.7 3.5 GO:0015265 urea channel activity(GO:0015265)
0.6 2.4 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.6 4.5 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.5 7.6 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.4 1.3 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.4 4.9 GO:0036310 annealing helicase activity(GO:0036310)
0.4 6.7 GO:0004890 GABA-A receptor activity(GO:0004890)
0.4 4.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.3 4.9 GO:0003688 DNA replication origin binding(GO:0003688)
0.3 8.8 GO:0070064 proline-rich region binding(GO:0070064)
0.3 0.9 GO:0016501 prostacyclin receptor activity(GO:0016501)
0.3 5.7 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.3 4.4 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.3 3.4 GO:0004000 adenosine deaminase activity(GO:0004000)
0.3 0.8 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.3 2.8 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.3 1.8 GO:0071253 connexin binding(GO:0071253)
0.2 13.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.2 1.2 GO:0051425 PTB domain binding(GO:0051425)
0.2 2.4 GO:0001055 RNA polymerase II activity(GO:0001055)
0.2 6.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.2 1.5 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.2 4.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2 1.0 GO:0000403 Y-form DNA binding(GO:0000403)
0.2 0.6 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.2 0.8 GO:0042895 antibiotic transporter activity(GO:0042895)
0.2 4.9 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.2 3.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 0.8 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.6 GO:0004849 uridine kinase activity(GO:0004849)
0.1 3.0 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 3.2 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 9.1 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 3.1 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 1.4 GO:0051400 BH domain binding(GO:0051400)
0.1 0.9 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 9.5 GO:0005178 integrin binding(GO:0005178)
0.1 0.3 GO:0000992 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.1 8.4 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 5.7 GO:0008026 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) ATP-dependent helicase activity(GO:0008026) RNA-dependent ATPase activity(GO:0008186) purine NTP-dependent helicase activity(GO:0070035)
0.1 3.8 GO:0030145 manganese ion binding(GO:0030145)
0.1 1.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.8 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 0.5 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 0.4 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 3.1 GO:0008146 sulfotransferase activity(GO:0008146)
0.1 0.7 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 5.2 GO:0003777 microtubule motor activity(GO:0003777)
0.1 1.4 GO:0003785 actin monomer binding(GO:0003785)
0.1 15.0 GO:0003924 GTPase activity(GO:0003924)
0.0 4.4 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.3 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 1.3 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 1.2 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 8.5 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 3.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 2.1 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.3 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 6.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.4 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 3.9 GO:0031072 heat shock protein binding(GO:0031072)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 9.5 GO:0045296 cadherin binding(GO:0045296)
0.0 0.4 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 1.8 GO:0032947 protein complex scaffold(GO:0032947)
0.0 7.3 GO:0005509 calcium ion binding(GO:0005509)
0.0 1.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 24.0 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.5 6.3 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.4 19.3 PID_AURORA_A_PATHWAY Aurora A signaling
0.4 6.1 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.4 16.2 NABA_COLLAGENS Genes encoding collagen proteins
0.3 11.6 PID_ATR_PATHWAY ATR signaling pathway
0.2 6.3 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.2 3.3 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 4.6 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.2 4.6 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.2 9.3 PID_TXA2PATHWAY Thromboxane A2 receptor signaling
0.1 17.2 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 8.3 PID_FGF_PATHWAY FGF signaling pathway
0.1 3.1 PID_ARF6_PATHWAY Arf6 signaling events
0.1 4.9 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.1 1.8 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 3.4 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 2.4 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.0 3.0 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.9 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 3.4 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.3 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.8 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.3 ST_FAS_SIGNALING_PATHWAY Fas Signaling Pathway
0.0 1.7 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 13.4 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
1.0 8.3 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.9 14.4 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.8 15.5 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.6 6.3 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.5 5.8 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.4 3.4 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.3 28.4 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.3 1.8 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.3 8.2 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.3 3.7 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.2 3.3 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2 7.8 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.2 3.5 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.2 12.4 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 2.4 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 3.7 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.1 4.0 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 2.7 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.1 2.3 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 1.5 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.4 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.0 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 0.8 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 2.3 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.1 0.8 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.3 REACTOME_KINESINS Genes involved in Kinesins
0.0 4.2 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 1.2 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 1.0 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.6 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.3 REACTOME_ACTIVATION_OF_CHAPERONES_BY_ATF6_ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 2.2 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.4 REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.3 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.3 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis