Motif ID: Gsx1_Alx1_Mixl1_Lbx2

Z-value: 0.546


Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gsx1mm10_v2_chr5_+_147188678_147188696-0.305.6e-02Click!
Alx1mm10_v2_chr10_-_103028771_1030287820.241.3e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Gsx1_Alx1_Mixl1_Lbx2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_62766153 6.922 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr3_-_49757257 5.018 ENSMUST00000035931.7
Pcdh18
protocadherin 18
chr13_+_44121167 3.388 ENSMUST00000163056.1
ENSMUST00000159595.1
Gm5083

predicted gene 5083

chr2_+_116067213 3.151 ENSMUST00000152412.1
G630016G05Rik
RIKEN cDNA G630016G05 gene
chr7_+_103550368 3.001 ENSMUST00000106888.1
Olfr613
olfactory receptor 613
chr5_-_62765618 2.455 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr18_+_57468478 2.325 ENSMUST00000091892.2
Ctxn3
cortexin 3
chr1_-_190170671 2.273 ENSMUST00000175916.1
Prox1
prospero-related homeobox 1
chr2_-_116067391 2.208 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr1_-_163725123 2.116 ENSMUST00000159679.1
Mettl11b
methyltransferase like 11B
chr5_-_84417359 2.038 ENSMUST00000113401.1
Epha5
Eph receptor A5
chr11_-_98053415 2.036 ENSMUST00000017544.2
Stac2
SH3 and cysteine rich domain 2
chrX_+_56454871 1.857 ENSMUST00000039374.2
ENSMUST00000101553.2
Ddx26b

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

chr3_+_62419668 1.786 ENSMUST00000161057.1
Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chrM_+_7005 1.578 ENSMUST00000082405.1
mt-Co2
mitochondrially encoded cytochrome c oxidase II
chr5_+_17574726 1.429 ENSMUST00000169603.1
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr15_-_11037968 1.340 ENSMUST00000058007.5
Rxfp3
relaxin family peptide receptor 3
chr15_+_55307743 1.304 ENSMUST00000023053.5
ENSMUST00000110221.2
ENSMUST00000110217.3
Col14a1


collagen, type XIV, alpha 1


chr17_+_45734506 1.255 ENSMUST00000180558.1
F630040K05Rik
RIKEN cDNA F630040K05 gene
chr15_+_18818895 1.230 ENSMUST00000166873.2
Cdh10
cadherin 10
chr15_-_8710734 1.175 ENSMUST00000005493.7
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr1_-_72284248 1.172 ENSMUST00000097698.4
ENSMUST00000027381.6
Pecr

peroxisomal trans-2-enoyl-CoA reductase

chr3_-_66296807 1.139 ENSMUST00000029419.7
Veph1
ventricular zone expressed PH domain-containing 1
chr5_+_17574268 1.098 ENSMUST00000030568.7
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr8_-_120228221 1.096 ENSMUST00000183235.1
A330074K22Rik
RIKEN cDNA A330074K22 gene
chrM_+_2743 1.079 ENSMUST00000082392.1
mt-Nd1
mitochondrially encoded NADH dehydrogenase 1
chr1_+_137928100 1.057 ENSMUST00000054333.2
A130050O07Rik
RIKEN cDNA A130050O07 gene
chr2_+_152754156 1.053 ENSMUST00000010020.5
Cox4i2
cytochrome c oxidase subunit IV isoform 2
chrM_+_11734 0.990 ENSMUST00000082418.1
mt-Nd5
mitochondrially encoded NADH dehydrogenase 5
chr7_+_64185459 0.958 ENSMUST00000177102.2
ENSMUST00000107519.1
ENSMUST00000137650.1
ENSMUST00000032737.5
ENSMUST00000107515.1
ENSMUST00000144996.1
Trpm1





transient receptor potential cation channel, subfamily M, member 1





chr8_+_23411490 0.943 ENSMUST00000033952.7
Sfrp1
secreted frizzled-related protein 1
chr11_+_23306884 0.890 ENSMUST00000180046.1
Usp34
ubiquitin specific peptidase 34
chr5_+_13398688 0.888 ENSMUST00000125629.1
Sema3a
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chrX_-_157415286 0.875 ENSMUST00000079945.4
ENSMUST00000138396.1
Phex

phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)

chrM_+_10167 0.865 ENSMUST00000082414.1
mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr7_+_29071597 0.855 ENSMUST00000180926.1
Gm26604
predicted gene, 26604
chr11_+_29373618 0.808 ENSMUST00000040182.6
ENSMUST00000109477.1
Ccdc88a

coiled coil domain containing 88A

chr4_+_154964117 0.804 ENSMUST00000030931.4
ENSMUST00000070953.4
Pank4

pantothenate kinase 4

chr1_+_19103022 0.799 ENSMUST00000037294.7
Tfap2d
transcription factor AP-2, delta
chr11_+_23306910 0.790 ENSMUST00000137823.1
Usp34
ubiquitin specific peptidase 34
chr6_+_125552948 0.782 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Vwf


Von Willebrand factor homolog


chr4_-_155056784 0.781 ENSMUST00000131173.2
Plch2
phospholipase C, eta 2
chr7_-_19699008 0.767 ENSMUST00000174355.1
ENSMUST00000172983.1
ENSMUST00000174710.1
ENSMUST00000167646.2
ENSMUST00000003066.9
ENSMUST00000174064.1
Apoe





apolipoprotein E





chr6_+_145934113 0.696 ENSMUST00000032383.7
Sspn
sarcospan
chr12_-_25096080 0.669 ENSMUST00000020974.6
Id2
inhibitor of DNA binding 2
chr13_+_118714678 0.663 ENSMUST00000022246.8
Fgf10
fibroblast growth factor 10
chrX_-_37110257 0.645 ENSMUST00000076265.6
Upf3b
UPF3 regulator of nonsense transcripts homolog B (yeast)
chrX_+_150547375 0.640 ENSMUST00000066337.6
ENSMUST00000112715.1
Alas2

aminolevulinic acid synthase 2, erythroid

chr14_+_53324632 0.635 ENSMUST00000178100.1
Trav7n-6
T cell receptor alpha variable 7N-6
chr16_-_74411292 0.633 ENSMUST00000117200.1
Robo2
roundabout homolog 2 (Drosophila)
chrX_-_9256899 0.624 ENSMUST00000115553.2
Gm14862
predicted gene 14862
chr10_+_39612934 0.621 ENSMUST00000019987.6
Traf3ip2
TRAF3 interacting protein 2
chr5_-_70842617 0.616 ENSMUST00000031119.1
Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr4_+_108719649 0.614 ENSMUST00000178992.1
3110021N24Rik
RIKEN cDNA 3110021N24 gene
chr2_-_146511992 0.611 ENSMUST00000109986.2
Ralgapa2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr3_+_86070915 0.610 ENSMUST00000182666.1
Sh3d19
SH3 domain protein D19
chr6_-_126645784 0.606 ENSMUST00000055168.3
Kcna1
potassium voltage-gated channel, shaker-related subfamily, member 1
chr14_+_80000292 0.602 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr9_+_96258697 0.602 ENSMUST00000179416.1
Tfdp2
transcription factor Dp 2
chr13_-_97747373 0.592 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr4_-_24430838 0.588 ENSMUST00000183964.1
RP23-35K5.2
RP23-35K5.2
chr16_+_33684538 0.582 ENSMUST00000126532.1
Heg1
HEG homolog 1 (zebrafish)
chr14_+_124005355 0.579 ENSMUST00000166105.1
Gm17615
predicted gene, 17615
chr1_+_58210397 0.570 ENSMUST00000040442.5
Aox4
aldehyde oxidase 4
chr1_+_170308802 0.549 ENSMUST00000056991.5
1700015E13Rik
RIKEN cDNA 1700015E13 gene
chr12_+_49401277 0.549 ENSMUST00000056234.3
Gm9804
predicted gene 9804
chr4_-_154636831 0.533 ENSMUST00000030902.6
ENSMUST00000105637.1
ENSMUST00000070313.7
ENSMUST00000105636.1
ENSMUST00000105638.2
ENSMUST00000097759.2
ENSMUST00000124771.1
Prdm16






PR domain containing 16






chr9_-_123678782 0.519 ENSMUST00000170591.1
ENSMUST00000171647.1
Slc6a20a

solute carrier family 6 (neurotransmitter transporter), member 20A

chr13_-_83729544 0.509 ENSMUST00000181705.1
Gm26803
predicted gene, 26803
chr5_-_20882072 0.506 ENSMUST00000118174.1
Phtf2
putative homeodomain transcription factor 2
chr16_+_43503607 0.505 ENSMUST00000126100.1
ENSMUST00000123047.1
ENSMUST00000156981.1
Zbtb20


zinc finger and BTB domain containing 20


chr7_-_46667375 0.498 ENSMUST00000107669.2
Tph1
tryptophan hydroxylase 1
chr6_-_136875794 0.498 ENSMUST00000032342.1
Mgp
matrix Gla protein
chrM_+_7759 0.494 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr13_-_97747399 0.494 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr18_+_52767994 0.484 ENSMUST00000025413.7
ENSMUST00000163742.2
ENSMUST00000178011.1
Sncaip


synuclein, alpha interacting protein (synphilin)


chr16_-_45724600 0.482 ENSMUST00000096057.4
Tagln3
transgelin 3
chr17_-_47834682 0.465 ENSMUST00000066368.6
Mdfi
MyoD family inhibitor
chrX_-_139871637 0.463 ENSMUST00000033811.7
ENSMUST00000087401.5
Morc4

microrchidia 4

chr11_+_16752203 0.460 ENSMUST00000102884.3
ENSMUST00000020329.6
Egfr

epidermal growth factor receptor

chr3_+_94398517 0.453 ENSMUST00000050975.3
Lingo4
leucine rich repeat and Ig domain containing 4
chr4_-_87806296 0.453 ENSMUST00000126353.1
ENSMUST00000149357.1
Mllt3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr8_-_84662841 0.442 ENSMUST00000060427.4
Ier2
immediate early response 2
chr4_-_87806276 0.441 ENSMUST00000148059.1
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr2_-_146511899 0.436 ENSMUST00000131824.1
Ralgapa2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr8_-_105637403 0.431 ENSMUST00000182046.1
Gm5914
predicted gene 5914
chr3_-_130730375 0.421 ENSMUST00000079085.6
Rpl34
ribosomal protein L34
chr1_+_104768510 0.413 ENSMUST00000062528.8
Cdh20
cadherin 20
chr17_+_25188380 0.400 ENSMUST00000039734.5
Unkl
unkempt-like (Drosophila)
chr9_-_55919605 0.397 ENSMUST00000037408.8
Scaper
S phase cyclin A-associated protein in the ER
chr7_+_82337218 0.393 ENSMUST00000173828.1
Adamtsl3
ADAMTS-like 3
chr6_+_17749170 0.393 ENSMUST00000053148.7
ENSMUST00000115417.3
St7

suppression of tumorigenicity 7

chr7_+_51879041 0.376 ENSMUST00000107591.2
Gas2
growth arrest specific 2
chr3_+_32436151 0.371 ENSMUST00000029201.7
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr9_+_113930934 0.368 ENSMUST00000084885.5
ENSMUST00000009885.7
Ubp1

upstream binding protein 1

chr2_-_27475622 0.368 ENSMUST00000138693.1
ENSMUST00000113941.2
ENSMUST00000077737.6
Brd3


bromodomain containing 3


chr2_-_37359274 0.366 ENSMUST00000009174.8
Pdcl
phosducin-like
chr2_-_84425258 0.359 ENSMUST00000074262.2
Calcrl
calcitonin receptor-like
chr15_-_8710409 0.351 ENSMUST00000157065.1
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr12_-_4841583 0.347 ENSMUST00000020964.5
Fkbp1b
FK506 binding protein 1b
chr2_-_79456750 0.347 ENSMUST00000041099.4
Neurod1
neurogenic differentiation 1
chr12_-_111813834 0.342 ENSMUST00000021715.5
Xrcc3
X-ray repair complementing defective repair in Chinese hamster cells 3
chr6_+_134929118 0.342 ENSMUST00000185152.1
ENSMUST00000184504.1
RP23-45G16.5

RP23-45G16.5

chrM_-_14060 0.338 ENSMUST00000082419.1
mt-Nd6
mitochondrially encoded NADH dehydrogenase 6
chr7_+_5015466 0.329 ENSMUST00000086349.3
Zfp524
zinc finger protein 524
chr1_+_195017399 0.328 ENSMUST00000181273.1
A330023F24Rik
RIKEN cDNA A330023F24 gene
chr5_+_15516489 0.326 ENSMUST00000178227.1
Gm21847
predicted gene, 21847
chr5_+_135106881 0.322 ENSMUST00000005507.3
Mlxipl
MLX interacting protein-like
chr6_+_143285988 0.317 ENSMUST00000160951.1
D6Ertd474e
DNA segment, Chr 6, ERATO Doi 474, expressed
chr6_+_37870786 0.313 ENSMUST00000120428.1
ENSMUST00000031859.7
Trim24

tripartite motif-containing 24

chr5_-_137684665 0.312 ENSMUST00000100544.4
ENSMUST00000031736.9
ENSMUST00000151839.1
Agfg2


ArfGAP with FG repeats 2


chr12_+_102128718 0.312 ENSMUST00000159329.1
Slc24a4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr1_+_63176818 0.310 ENSMUST00000129339.1
Eef1b2
eukaryotic translation elongation factor 1 beta 2
chr17_-_51826562 0.308 ENSMUST00000024720.4
ENSMUST00000129667.1
ENSMUST00000156051.1
ENSMUST00000169480.1
ENSMUST00000148559.1
Satb1




special AT-rich sequence binding protein 1




chr15_-_42676967 0.306 ENSMUST00000022921.5
Angpt1
angiopoietin 1
chr12_+_84361968 0.304 ENSMUST00000021661.6
Coq6
coenzyme Q6 homolog (yeast)
chr13_-_27582168 0.304 ENSMUST00000006664.1
ENSMUST00000095926.1
Prl8a1

prolactin family 8, subfamily a, member 1

chr5_-_107875035 0.302 ENSMUST00000138111.1
ENSMUST00000112642.1
Evi5

ecotropic viral integration site 5

chr15_+_25773985 0.298 ENSMUST00000125667.1
Myo10
myosin X
chr16_-_65562686 0.298 ENSMUST00000004965.6
Chmp2b
charged multivesicular body protein 2B
chr7_+_114745685 0.297 ENSMUST00000136645.1
ENSMUST00000169913.1
Insc

inscuteable homolog (Drosophila)

chr13_+_94083490 0.296 ENSMUST00000156071.1
Lhfpl2
lipoma HMGIC fusion partner-like 2
chr2_-_45112890 0.290 ENSMUST00000076836.6
Zeb2
zinc finger E-box binding homeobox 2
chr6_-_57535422 0.288 ENSMUST00000042766.3
Ppm1k
protein phosphatase 1K (PP2C domain containing)
chr19_+_26749726 0.288 ENSMUST00000175842.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chrX_+_159697308 0.288 ENSMUST00000123433.1
Sh3kbp1
SH3-domain kinase binding protein 1
chr1_-_90843916 0.287 ENSMUST00000130846.2
ENSMUST00000097653.4
ENSMUST00000056925.9
Col6a3


collagen, type VI, alpha 3


chr17_-_57247632 0.286 ENSMUST00000005975.6
Gpr108
G protein-coupled receptor 108
chr3_+_66219909 0.285 ENSMUST00000029421.5
Ptx3
pentraxin related gene
chr16_-_97170707 0.283 ENSMUST00000056102.7
Dscam
Down syndrome cell adhesion molecule
chr15_+_82016369 0.282 ENSMUST00000069530.6
Xrcc6
X-ray repair complementing defective repair in Chinese hamster cells 6
chr11_+_116843278 0.282 ENSMUST00000106370.3
Mettl23
methyltransferase like 23
chr8_-_67818284 0.280 ENSMUST00000120071.1
Psd3
pleckstrin and Sec7 domain containing 3
chr2_+_125136692 0.277 ENSMUST00000099452.2
Ctxn2
cortexin 2
chr17_-_48451510 0.277 ENSMUST00000024794.5
Tspo2
translocator protein 2
chr13_+_76579670 0.277 ENSMUST00000126960.1
ENSMUST00000109583.2
Mctp1

multiple C2 domains, transmembrane 1

chr9_-_96719404 0.270 ENSMUST00000140121.1
Zbtb38
zinc finger and BTB domain containing 38
chr9_+_118478182 0.267 ENSMUST00000111763.1
Eomes
eomesodermin homolog (Xenopus laevis)
chr18_+_37518341 0.263 ENSMUST00000097609.1
Pcdhb22
protocadherin beta 22
chr14_+_55559993 0.251 ENSMUST00000117236.1
Dcaf11
DDB1 and CUL4 associated factor 11
chr16_+_14705832 0.247 ENSMUST00000023356.6
Snai2
snail homolog 2 (Drosophila)
chr3_-_87930121 0.246 ENSMUST00000005016.9
Rrnad1
ribosomal RNA adenine dimethylase domain containing 1
chr9_-_96719549 0.244 ENSMUST00000128269.1
Zbtb38
zinc finger and BTB domain containing 38
chr15_-_37459327 0.239 ENSMUST00000119730.1
ENSMUST00000120746.1
Ncald

neurocalcin delta

chr7_+_30565410 0.239 ENSMUST00000043850.7
Igflr1
IGF-like family receptor 1
chr17_+_46161021 0.237 ENSMUST00000024748.7
ENSMUST00000172170.1
Gtpbp2

GTP binding protein 2

chr15_+_36179299 0.236 ENSMUST00000047348.3
Spag1
sperm associated antigen 1
chrX_+_103356464 0.233 ENSMUST00000116547.2
Chic1
cysteine-rich hydrophobic domain 1
chr12_-_75735729 0.233 ENSMUST00000021450.4
Sgpp1
sphingosine-1-phosphate phosphatase 1
chr14_-_76010863 0.232 ENSMUST00000088922.4
Gtf2f2
general transcription factor IIF, polypeptide 2
chr13_-_103764502 0.230 ENSMUST00000074616.5
Srek1
splicing regulatory glutamine/lysine-rich protein 1
chr18_+_23415400 0.222 ENSMUST00000115832.2
ENSMUST00000047954.7
Dtna

dystrobrevin alpha

chr4_-_42661893 0.221 ENSMUST00000108006.3
Il11ra2
interleukin 11 receptor, alpha chain 2
chr3_+_32436376 0.220 ENSMUST00000108242.1
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr3_+_108186332 0.219 ENSMUST00000050909.6
ENSMUST00000106659.2
ENSMUST00000106656.1
ENSMUST00000106661.2
Amigo1



adhesion molecule with Ig like domain 1



chr11_-_87359011 0.219 ENSMUST00000055438.4
Ppm1e
protein phosphatase 1E (PP2C domain containing)
chrX_+_8271133 0.217 ENSMUST00000127103.1
ENSMUST00000115591.1
Slc38a5

solute carrier family 38, member 5

chrM_+_9870 0.216 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr3_-_146495115 0.214 ENSMUST00000093951.2
Spata1
spermatogenesis associated 1
chrM_+_8600 0.210 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chrX_+_16619698 0.210 ENSMUST00000026013.5
Maoa
monoamine oxidase A
chr2_-_144527341 0.209 ENSMUST00000163701.1
ENSMUST00000081982.5
Dzank1

double zinc ribbon and ankyrin repeat domains 1

chr15_+_9436028 0.208 ENSMUST00000042360.3
Capsl
calcyphosine-like
chr9_+_13827708 0.207 ENSMUST00000059579.5
Fam76b
family with sequence similarity 76, member B
chr5_+_34999111 0.203 ENSMUST00000114283.1
Rgs12
regulator of G-protein signaling 12
chr8_+_121116163 0.200 ENSMUST00000054691.6
Foxc2
forkhead box C2
chr9_+_118478344 0.199 ENSMUST00000035020.8
Eomes
eomesodermin homolog (Xenopus laevis)
chr6_-_85765744 0.199 ENSMUST00000050780.7
Cml3
camello-like 3
chr8_+_83666827 0.198 ENSMUST00000019608.5
Ptger1
prostaglandin E receptor 1 (subtype EP1)
chr10_-_128744014 0.198 ENSMUST00000026414.7
Dgka
diacylglycerol kinase, alpha
chr5_+_34999070 0.196 ENSMUST00000114280.1
Rgs12
regulator of G-protein signaling 12
chr19_-_42129043 0.196 ENSMUST00000018965.3
Avpi1
arginine vasopressin-induced 1
chr16_+_33684460 0.195 ENSMUST00000152782.1
ENSMUST00000179453.1
Heg1

HEG homolog 1 (zebrafish)

chr4_-_109665249 0.194 ENSMUST00000063531.4
Cdkn2c
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr4_-_14621805 0.193 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chrX_-_133981765 0.190 ENSMUST00000113297.2
ENSMUST00000174542.1
ENSMUST00000033608.8
ENSMUST00000113294.1
Sytl4



synaptotagmin-like 4



chrX_-_74246534 0.190 ENSMUST00000101454.2
ENSMUST00000033699.6
Flna

filamin, alpha

chr1_+_165769392 0.190 ENSMUST00000040298.4
Creg1
cellular repressor of E1A-stimulated genes 1
chr1_-_140183404 0.189 ENSMUST00000066859.6
ENSMUST00000111976.2
Cfh

complement component factor h

chr9_+_21927471 0.189 ENSMUST00000170304.1
ENSMUST00000006403.6
Ccdc159

coiled-coil domain containing 159

chr9_-_123678873 0.186 ENSMUST00000040960.6
Slc6a20a
solute carrier family 6 (neurotransmitter transporter), member 20A
chr10_-_88683021 0.185 ENSMUST00000004473.8
Spic
Spi-C transcription factor (Spi-1/PU.1 related)
chr17_+_35424842 0.180 ENSMUST00000174699.1
H2-Q6
histocompatibility 2, Q region locus 6
chr5_+_8660059 0.180 ENSMUST00000047753.4
Abcb1a
ATP-binding cassette, sub-family B (MDR/TAP), member 1A
chr3_-_106790143 0.180 ENSMUST00000038845.8
Cd53
CD53 antigen
chr16_-_63864114 0.179 ENSMUST00000064405.6
Epha3
Eph receptor A3
chr4_+_123016590 0.178 ENSMUST00000102649.3
Trit1
tRNA isopentenyltransferase 1
chr7_+_49910112 0.178 ENSMUST00000056442.5
Slc6a5
solute carrier family 6 (neurotransmitter transporter, glycine), member 5
chr1_+_153751859 0.177 ENSMUST00000182538.1
Rnasel
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
chr1_+_10056922 0.177 ENSMUST00000149214.1
Cspp1
centrosome and spindle pole associated protein 1
chr5_+_34999046 0.176 ENSMUST00000114281.1
Rgs12
regulator of G-protein signaling 12
chr12_+_59066908 0.176 ENSMUST00000021381.4
Pnn
pinin
chr4_-_15149755 0.175 ENSMUST00000108273.1
Necab1
N-terminal EF-hand calcium binding protein 1
chr15_-_50890396 0.175 ENSMUST00000185183.1
Trps1
trichorhinophalangeal syndrome I (human)
chr15_+_21111452 0.175 ENSMUST00000075132.6
Cdh12
cadherin 12
chrX_+_101640056 0.173 ENSMUST00000119299.1
ENSMUST00000044475.4
Ogt

O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)

chr12_+_111814170 0.172 ENSMUST00000021714.7
Zfyve21
zinc finger, FYVE domain containing 21
chr3_-_79628660 0.171 ENSMUST00000120992.1
Etfdh
electron transferring flavoprotein, dehydrogenase
chr18_-_39487096 0.169 ENSMUST00000097592.2
ENSMUST00000115571.1
Nr3c1

nuclear receptor subfamily 3, group C, member 1

chr8_-_67818218 0.169 ENSMUST00000059374.4
Psd3
pleckstrin and Sec7 domain containing 3

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.5 3.4 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.3 1.6 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.3 1.3 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.3 0.8 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.3 0.8 GO:1903002 regulation of lipid transport across blood brain barrier(GO:1903000) positive regulation of lipid transport across blood brain barrier(GO:1903002)
0.2 2.2 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.2 0.7 GO:0071336 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.2 0.6 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.2 1.0 GO:0060178 regulation of exocyst localization(GO:0060178)
0.2 4.8 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.2 0.6 GO:0050975 sensory perception of touch(GO:0050975)
0.2 0.6 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.2 0.6 GO:0046110 xanthine metabolic process(GO:0046110)
0.2 0.8 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.2 0.5 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.1 0.4 GO:1902605 heterotrimeric G-protein complex assembly(GO:1902605)
0.1 0.6 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.1 1.1 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.3 GO:0030210 heparin biosynthetic process(GO:0030210) Tie signaling pathway(GO:0048014)
0.1 1.0 GO:0015824 proline transport(GO:0015824)
0.1 0.3 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.1 1.8 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.6 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 0.5 GO:0070459 prolactin secretion(GO:0070459)
0.1 0.4 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1 0.3 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 1.2 GO:0030497 fatty acid elongation(GO:0030497)
0.1 0.3 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.1 0.2 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.1 0.5 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.1 2.6 GO:0007608 sensory perception of smell(GO:0007608)
0.1 3.6 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.1 1.0 GO:0046548 retinal rod cell development(GO:0046548)
0.1 0.3 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.1 0.4 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.1 1.3 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.1 0.2 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) glomerular mesangial cell differentiation(GO:0072008) glomerular mesangial cell development(GO:0072144) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.1 0.2 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.1 0.5 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.1 1.7 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 2.1 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.1 0.2 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 0.2 GO:0036233 glycine import(GO:0036233)
0.1 0.2 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.1 0.2 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.3 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.1 0.9 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.8 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.2 GO:0042420 dopamine catabolic process(GO:0042420)
0.1 0.3 GO:0045919 complement activation, alternative pathway(GO:0006957) positive regulation of cytolysis(GO:0045919)
0.0 0.1 GO:0051795 positive regulation of catagen(GO:0051795)
0.0 0.3 GO:0060315 response to redox state(GO:0051775) negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 1.4 GO:0061050 regulation of cell growth involved in cardiac muscle cell development(GO:0061050)
0.0 0.2 GO:0046618 drug export(GO:0046618)
0.0 0.2 GO:0015816 glycine transport(GO:0015816)
0.0 0.3 GO:0090656 t-circle formation(GO:0090656)
0.0 0.1 GO:0061738 late endosomal microautophagy(GO:0061738) ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0 0.2 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0 0.6 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.5 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.0 0.8 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.2 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.1 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.6 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.9 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.1 GO:0045113 regulation of integrin biosynthetic process(GO:0045113)
0.0 0.1 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0051593 response to folic acid(GO:0051593)
0.0 0.1 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.5 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.1 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361) termination of RNA polymerase I transcription(GO:0006363)
0.0 0.1 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.0 0.1 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.3 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.2 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091) negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.4 GO:0022904 respiratory electron transport chain(GO:0022904)
0.0 0.6 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 0.1 GO:1904659 glucose transmembrane transport(GO:1904659)
0.0 0.2 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.1 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.3 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.2 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.3 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.5 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.0 0.2 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.5 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.4 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.1 GO:0019532 oxalate transport(GO:0019532)
0.0 0.2 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.6 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.0 GO:1903546 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.0 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630) positive regulation of aminoacyl-tRNA ligase activity(GO:1903632)
0.0 0.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.2 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0097264 self proteolysis(GO:0097264)
0.0 0.1 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.1 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.0 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.2 GO:0042438 melanin biosynthetic process(GO:0042438)
0.0 0.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.1 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.2 0.6 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.2 2.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 0.8 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.5 GO:0097487 vesicle lumen(GO:0031983) multivesicular body, internal vesicle(GO:0097487)
0.1 1.3 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.3 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.1 1.0 GO:0051286 cell tip(GO:0051286)
0.1 0.9 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 3.6 GO:0070469 respiratory chain(GO:0070469)
0.0 0.5 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.2 GO:0031523 Myb complex(GO:0031523)
0.0 0.3 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.6 GO:0042581 specific granule(GO:0042581)
0.0 0.2 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.0 0.2 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.4 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.1 GO:0032807 DNA ligase IV complex(GO:0032807)
0.0 0.1 GO:0097449 astrocyte projection(GO:0097449)
0.0 0.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 1.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.8 GO:0030673 axolemma(GO:0030673)
0.0 1.0 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 1.2 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.6 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)
0.0 0.6 GO:0016235 aggresome(GO:0016235)
0.0 0.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.5 GO:0097440 apical dendrite(GO:0097440)
0.0 0.2 GO:0042588 zymogen granule(GO:0042588)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.8 GO:0072562 blood microparticle(GO:0072562)
0.0 0.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.1 GO:0005796 Golgi lumen(GO:0005796)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.2 GO:0004984 olfactory receptor activity(GO:0004984)
0.4 1.2 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.3 1.3 GO:0004966 galanin receptor activity(GO:0004966)
0.3 2.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.3 3.6 GO:0038191 neuropilin binding(GO:0038191)
0.3 0.8 GO:0046911 hydroxyapatite binding(GO:0046848) metal chelating activity(GO:0046911) phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.3 1.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.2 0.6 GO:0016748 succinyltransferase activity(GO:0016748)
0.2 9.6 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.2 2.3 GO:0050693 LBD domain binding(GO:0050693)
0.2 0.5 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.2 0.7 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.2 0.8 GO:0004594 pantothenate kinase activity(GO:0004594)
0.2 0.5 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.6 GO:0030151 molybdenum ion binding(GO:0030151)
0.1 2.9 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 1.0 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 3.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.2 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 0.6 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.5 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.2 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 0.8 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 0.3 GO:0001851 complement component C3b binding(GO:0001851)
0.1 0.6 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 0.4 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 0.2 GO:0051378 primary amine oxidase activity(GO:0008131) serotonin binding(GO:0051378)
0.1 0.2 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.4 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.1 GO:0098809 nitrite reductase activity(GO:0098809)
0.0 0.4 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.0 0.3 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.3 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.2 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.2 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.6 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.2 GO:0004954 icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)
0.0 0.5 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.9 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.1 GO:0019153 protein-disulfide reductase (glutathione) activity(GO:0019153)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.3 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.2 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.3 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.3 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 1.9 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.2 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 1.4 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0035004 1-phosphatidylinositol-3-kinase activity(GO:0016303) phosphatidylinositol 3-kinase activity(GO:0035004)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.3 GO:0071949 FAD binding(GO:0071949)
0.0 0.2 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0003681 bent DNA binding(GO:0003681)
0.0 0.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 1.0 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0051400 BH domain binding(GO:0051400)
0.0 0.4 GO:0070412 R-SMAD binding(GO:0070412)
0.0 5.9 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 1.0 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 9.2 PID_ARF6_PATHWAY Arf6 signaling events
0.0 1.4 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.6 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 3.4 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.5 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 2.8 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.3 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.5 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 0.4 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.5 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.5 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.7 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 0.5 PID_IL12_2PATHWAY IL12-mediated signaling events
0.0 0.8 PID_E2F_PATHWAY E2F transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.1 0.2 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 0.8 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 0.3 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.1 0.8 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 0.8 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 9.5 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.5 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.0 0.9 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 1.9 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.5 REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 1.1 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.6 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.1 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.2 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.4 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.3 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.0 0.6 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.7 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME_INTEGRATION_OF_PROVIRUS Genes involved in Integration of provirus
0.0 0.1 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.3 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.2 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.3 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.6 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.2 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.2 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.3 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.2 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.1 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.4 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.1 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.2 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.1 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis