Motif ID: Dlx1

Z-value: 0.874


Transcription factors associated with Dlx1:

Gene SymbolEntrez IDGene Name
Dlx1 ENSMUSG00000041911.3 Dlx1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Dlx1mm10_v2_chr2_+_71529085_715291100.371.8e-02Click!


Activity profile for motif Dlx1.

activity profile for motif Dlx1


Sorted Z-values histogram for motif Dlx1

Sorted Z-values for motif Dlx1



Network of associatons between targets according to the STRING database.



First level regulatory network of Dlx1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_8710734 4.743 ENSMUST00000005493.7
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr12_+_84069325 4.070 ENSMUST00000046422.4
ENSMUST00000072505.4
Acot5

acyl-CoA thioesterase 5

chr15_-_8710409 3.770 ENSMUST00000157065.1
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr6_-_101377897 3.435 ENSMUST00000075994.6
Pdzrn3
PDZ domain containing RING finger 3
chr3_+_66219909 2.887 ENSMUST00000029421.5
Ptx3
pentraxin related gene
chr8_+_94152607 2.600 ENSMUST00000034211.8
Mt3
metallothionein 3
chr1_+_58210397 2.518 ENSMUST00000040442.5
Aox4
aldehyde oxidase 4
chr6_-_36811361 2.506 ENSMUST00000101534.1
Ptn
pleiotrophin
chr14_+_80000292 2.476 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr11_-_98053415 2.305 ENSMUST00000017544.2
Stac2
SH3 and cysteine rich domain 2
chr8_+_94172618 2.156 ENSMUST00000034214.6
Mt2
metallothionein 2
chr2_+_22622183 2.139 ENSMUST00000028123.3
Gad2
glutamic acid decarboxylase 2
chr3_+_121953213 2.110 ENSMUST00000037958.7
ENSMUST00000128366.1
Arhgap29

Rho GTPase activating protein 29

chr5_+_107403496 2.064 ENSMUST00000049146.5
Ephx4
epoxide hydrolase 4
chr13_+_94083490 2.033 ENSMUST00000156071.1
Lhfpl2
lipoma HMGIC fusion partner-like 2
chrX_+_150547375 2.012 ENSMUST00000066337.6
ENSMUST00000112715.1
Alas2

aminolevulinic acid synthase 2, erythroid

chr5_-_70842617 1.611 ENSMUST00000031119.1
Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr15_-_37458523 1.607 ENSMUST00000116445.2
Ncald
neurocalcin delta
chr2_+_91257323 1.573 ENSMUST00000111349.2
ENSMUST00000131711.1
Pacsin3

protein kinase C and casein kinase substrate in neurons 3

chr11_+_114675431 1.488 ENSMUST00000045779.5
Ttyh2
tweety homolog 2 (Drosophila)
chr3_+_62419668 1.473 ENSMUST00000161057.1
Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr13_-_41487306 1.433 ENSMUST00000021794.6
Nedd9
neural precursor cell expressed, developmentally down-regulated gene 9
chr15_-_71954395 1.379 ENSMUST00000159410.1
Col22a1
collagen, type XXII, alpha 1
chr2_+_116067213 1.366 ENSMUST00000152412.1
G630016G05Rik
RIKEN cDNA G630016G05 gene
chr7_-_45103747 1.354 ENSMUST00000003512.7
Fcgrt
Fc receptor, IgG, alpha chain transporter
chr4_+_128058962 1.323 ENSMUST00000184063.1
Csmd2
CUB and Sushi multiple domains 2
chr8_+_23411490 1.293 ENSMUST00000033952.7
Sfrp1
secreted frizzled-related protein 1
chr4_+_102589687 1.262 ENSMUST00000097949.4
ENSMUST00000106901.1
Pde4b

phosphodiesterase 4B, cAMP specific

chr6_+_30541582 1.246 ENSMUST00000096066.4
Cpa2
carboxypeptidase A2, pancreatic
chr14_-_64455903 1.208 ENSMUST00000067927.7
Msra
methionine sulfoxide reductase A
chr4_-_14621805 1.204 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr3_-_154330543 1.188 ENSMUST00000184966.1
ENSMUST00000177846.2
Lhx8

LIM homeobox protein 8

chr13_+_29016267 1.149 ENSMUST00000140415.1
A330102I10Rik
RIKEN cDNA A330102I10 gene
chr8_+_66386292 1.118 ENSMUST00000039540.5
ENSMUST00000110253.2
March1

membrane-associated ring finger (C3HC4) 1

chrX_-_57338598 1.087 ENSMUST00000033468.4
ENSMUST00000114736.1
Arhgef6

Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6

chr1_-_163725123 1.084 ENSMUST00000159679.1
Mettl11b
methyltransferase like 11B
chr2_-_34913976 1.080 ENSMUST00000028232.3
Phf19
PHD finger protein 19
chr10_-_81407641 1.068 ENSMUST00000140916.1
Nfic
nuclear factor I/C
chr13_-_105271039 1.057 ENSMUST00000069686.6
Rnf180
ring finger protein 180
chr5_+_66968416 1.053 ENSMUST00000038188.7
Limch1
LIM and calponin homology domains 1
chr15_-_37459327 1.043 ENSMUST00000119730.1
ENSMUST00000120746.1
Ncald

neurocalcin delta

chr2_+_4300462 1.041 ENSMUST00000175669.1
Frmd4a
FERM domain containing 4A
chr19_-_32196393 1.008 ENSMUST00000151822.1
Sgms1
sphingomyelin synthase 1
chr18_-_39487096 1.002 ENSMUST00000097592.2
ENSMUST00000115571.1
Nr3c1

nuclear receptor subfamily 3, group C, member 1

chr16_+_43247278 0.994 ENSMUST00000114691.1
ENSMUST00000079441.6
Zbtb20

zinc finger and BTB domain containing 20

chr4_+_102570065 0.949 ENSMUST00000097950.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr19_-_59076069 0.946 ENSMUST00000047511.7
ENSMUST00000163821.1
4930506M07Rik

RIKEN cDNA 4930506M07 gene

chr7_+_19368498 0.894 ENSMUST00000132655.1
Ppp1r13l
protein phosphatase 1, regulatory (inhibitor) subunit 13 like
chr5_+_66968559 0.892 ENSMUST00000127184.1
Limch1
LIM and calponin homology domains 1
chr4_+_15881255 0.887 ENSMUST00000029876.1
Calb1
calbindin 1
chr5_-_92278155 0.873 ENSMUST00000159345.1
ENSMUST00000113102.3
Naaa

N-acylethanolamine acid amidase

chr6_-_108185552 0.868 ENSMUST00000167338.1
ENSMUST00000172188.1
ENSMUST00000032191.9
Sumf1


sulfatase modifying factor 1


chr15_+_98571004 0.861 ENSMUST00000023728.6
4930415O20Rik
RIKEN cDNA 4930415O20 gene
chr19_-_50678642 0.856 ENSMUST00000072685.6
ENSMUST00000164039.2
Sorcs1

VPS10 domain receptor protein SORCS 1

chr11_-_42182924 0.836 ENSMUST00000020707.5
ENSMUST00000132971.1
Gabra1

gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1

chr4_-_138396438 0.816 ENSMUST00000105032.2
Fam43b
family with sequence similarity 43, member B
chr1_-_155527083 0.797 ENSMUST00000097531.2
Gm5532
predicted gene 5532
chr9_-_90255927 0.791 ENSMUST00000144646.1
Tbc1d2b
TBC1 domain family, member 2B
chr15_-_11037968 0.783 ENSMUST00000058007.5
Rxfp3
relaxin family peptide receptor 3
chr5_+_19907502 0.769 ENSMUST00000101558.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr10_-_18743691 0.769 ENSMUST00000019999.5
D10Bwg1379e
DNA segment, Chr 10, Brigham & Women's Genetics 1379 expressed
chr6_+_113333304 0.764 ENSMUST00000147945.1
Ogg1
8-oxoguanine DNA-glycosylase 1
chrX_-_134111852 0.755 ENSMUST00000033610.6
Nox1
NADPH oxidase 1
chr6_-_137169710 0.733 ENSMUST00000117919.1
Rerg
RAS-like, estrogen-regulated, growth-inhibitor
chr6_+_145934113 0.731 ENSMUST00000032383.7
Sspn
sarcospan
chrX_+_170009892 0.729 ENSMUST00000180251.1
Gm21887
predicted gene, 21887
chr8_-_21906412 0.729 ENSMUST00000051965.4
Defb11
defensin beta 11
chr6_+_86195214 0.729 ENSMUST00000032066.9
Tgfa
transforming growth factor alpha
chr14_-_48665098 0.720 ENSMUST00000118578.1
Otx2
orthodenticle homolog 2 (Drosophila)
chr19_+_26749726 0.711 ENSMUST00000175842.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr3_+_103575275 0.711 ENSMUST00000090697.4
Syt6
synaptotagmin VI
chr19_+_5474681 0.701 ENSMUST00000165485.1
ENSMUST00000166253.1
ENSMUST00000167371.1
ENSMUST00000167855.1
ENSMUST00000070118.7
Efemp2




epidermal growth factor-containing fibulin-like extracellular matrix protein 2




chr17_-_45659312 0.701 ENSMUST00000120717.1
Capn11
calpain 11
chr6_+_72097561 0.695 ENSMUST00000069994.4
ENSMUST00000114112.1
St3gal5

ST3 beta-galactoside alpha-2,3-sialyltransferase 5

chr11_+_109543694 0.645 ENSMUST00000106696.1
Arsg
arylsulfatase G
chr11_+_117809687 0.637 ENSMUST00000120928.1
ENSMUST00000175737.1
Syngr2

synaptogyrin 2

chr9_+_72985504 0.636 ENSMUST00000156879.1
Ccpg1
cell cycle progression 1
chr19_+_55895508 0.632 ENSMUST00000111646.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr2_+_131491764 0.620 ENSMUST00000028806.5
ENSMUST00000110179.2
ENSMUST00000110189.2
ENSMUST00000110182.2
ENSMUST00000110183.2
ENSMUST00000110186.2
ENSMUST00000110188.1
Smox






spermine oxidase






chr16_-_3908596 0.620 ENSMUST00000123235.2
1700037C18Rik
RIKEN cDNA 1700037C18 gene
chr7_-_140154712 0.611 ENSMUST00000059241.7
Sprn
shadow of prion protein
chr2_+_109917639 0.605 ENSMUST00000046548.7
ENSMUST00000111037.2
Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chr1_-_72284248 0.597 ENSMUST00000097698.4
ENSMUST00000027381.6
Pecr

peroxisomal trans-2-enoyl-CoA reductase

chr1_-_152625212 0.595 ENSMUST00000027760.7
Rgl1
ral guanine nucleotide dissociation stimulator,-like 1
chr8_+_69226343 0.595 ENSMUST00000110216.1
Zfp930
zinc finger protein 930
chr17_-_36032682 0.595 ENSMUST00000102678.4
H2-T23
histocompatibility 2, T region locus 23
chrY_+_90785442 0.594 ENSMUST00000177591.1
ENSMUST00000177671.1
ENSMUST00000179077.1
Erdr1


erythroid differentiation regulator 1


chrX_+_99042581 0.591 ENSMUST00000036606.7
Stard8
START domain containing 8
chr18_+_36281069 0.582 ENSMUST00000051301.3
Pura
purine rich element binding protein A
chr5_+_107497718 0.566 ENSMUST00000112671.2
A830010M20Rik
RIKEN cDNA A830010M20 gene
chr14_-_18893376 0.549 ENSMUST00000151926.1
Ube2e2
ubiquitin-conjugating enzyme E2E 2
chr7_+_27452417 0.547 ENSMUST00000108357.1
Blvrb
biliverdin reductase B (flavin reductase (NADPH))
chr7_+_44896125 0.544 ENSMUST00000166552.1
ENSMUST00000168207.1
Fuz

fuzzy homolog (Drosophila)

chr13_+_43785107 0.537 ENSMUST00000015540.2
Cd83
CD83 antigen
chr9_-_51963533 0.537 ENSMUST00000034552.6
Fdx1
ferredoxin 1
chr2_-_116067391 0.532 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr18_+_37411674 0.532 ENSMUST00000051126.2
Pcdhb10
protocadherin beta 10
chr3_-_152193803 0.531 ENSMUST00000050073.6
Dnajb4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr17_+_17316078 0.525 ENSMUST00000105311.3
Gm6712
predicted gene 6712
chr7_+_101378183 0.523 ENSMUST00000084895.5
Arap1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr9_+_92457369 0.522 ENSMUST00000034941.7
Plscr4
phospholipid scramblase 4
chr18_+_23415400 0.514 ENSMUST00000115832.2
ENSMUST00000047954.7
Dtna

dystrobrevin alpha

chr7_-_133782721 0.506 ENSMUST00000063669.1
Dhx32
DEAH (Asp-Glu-Ala-His) box polypeptide 32
chr12_-_75735729 0.500 ENSMUST00000021450.4
Sgpp1
sphingosine-1-phosphate phosphatase 1
chr11_+_116843278 0.497 ENSMUST00000106370.3
Mettl23
methyltransferase like 23
chr5_+_19907774 0.493 ENSMUST00000115267.2
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr19_+_46689902 0.485 ENSMUST00000074912.7
2010012O05Rik
RIKEN cDNA 2010012O05 gene
chr5_+_29195983 0.483 ENSMUST00000160888.1
ENSMUST00000159272.1
ENSMUST00000001247.5
ENSMUST00000161398.1
ENSMUST00000160246.1
Rnf32




ring finger protein 32




chr14_-_45388772 0.481 ENSMUST00000046191.7
Gnpnat1
glucosamine-phosphate N-acetyltransferase 1
chr11_-_80377975 0.481 ENSMUST00000179332.1
ENSMUST00000103225.4
ENSMUST00000134274.1
5730455P16Rik


RIKEN cDNA 5730455P16 gene


chr13_+_52596847 0.475 ENSMUST00000055087.6
Syk
spleen tyrosine kinase
chr10_+_90071095 0.470 ENSMUST00000183109.1
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr5_-_106926245 0.458 ENSMUST00000117588.1
Hfm1
HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
chr5_+_3543812 0.456 ENSMUST00000115527.3
Fam133b
family with sequence similarity 133, member B
chr5_-_62766153 0.449 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr4_-_40722307 0.446 ENSMUST00000181475.1
Gm6297
predicted gene 6297
chr19_-_19001099 0.444 ENSMUST00000040153.8
ENSMUST00000112828.1
Rorb

RAR-related orphan receptor beta

chr1_+_82316452 0.444 ENSMUST00000027322.7
Rhbdd1
rhomboid domain containing 1
chr2_+_96318014 0.439 ENSMUST00000135431.1
ENSMUST00000162807.2
Lrrc4c

leucine rich repeat containing 4C

chr3_+_63295815 0.438 ENSMUST00000029400.1
Mme
membrane metallo endopeptidase
chr9_-_123678782 0.436 ENSMUST00000170591.1
ENSMUST00000171647.1
Slc6a20a

solute carrier family 6 (neurotransmitter transporter), member 20A

chr1_-_22315792 0.436 ENSMUST00000164877.1
Rims1
regulating synaptic membrane exocytosis 1
chr1_+_125561010 0.431 ENSMUST00000027580.4
Slc35f5
solute carrier family 35, member F5
chr19_+_53140430 0.429 ENSMUST00000111741.2
Add3
adducin 3 (gamma)
chr18_+_37435602 0.429 ENSMUST00000055495.5
Pcdhb12
protocadherin beta 12
chr9_-_123678873 0.412 ENSMUST00000040960.6
Slc6a20a
solute carrier family 6 (neurotransmitter transporter), member 20A
chr19_-_34527396 0.410 ENSMUST00000049572.8
ENSMUST00000178114.1
Lipa

lysosomal acid lipase A

chrY_+_90784738 0.405 ENSMUST00000179483.1
Erdr1
erythroid differentiation regulator 1
chr5_-_145201829 0.402 ENSMUST00000162220.1
ENSMUST00000031632.8
Zkscan14

zinc finger with KRAB and SCAN domains 14

chr11_+_117809653 0.401 ENSMUST00000026649.7
ENSMUST00000177131.1
ENSMUST00000132298.1
Syngr2

Gm20708
synaptogyrin 2

predicted gene 20708
chr2_-_10130638 0.399 ENSMUST00000042290.7
Itih2
inter-alpha trypsin inhibitor, heavy chain 2
chr7_-_126676357 0.397 ENSMUST00000106371.1
ENSMUST00000106372.3
ENSMUST00000155419.1
Sult1a1


sulfotransferase family 1A, phenol-preferring, member 1


chr9_-_15301555 0.394 ENSMUST00000034414.8
4931406C07Rik
RIKEN cDNA 4931406C07 gene
chr3_-_130730375 0.390 ENSMUST00000079085.6
Rpl34
ribosomal protein L34
chrX_+_42068398 0.388 ENSMUST00000115095.2
Xiap
X-linked inhibitor of apoptosis
chr11_-_40695203 0.381 ENSMUST00000101347.3
Mat2b
methionine adenosyltransferase II, beta
chr6_-_54593139 0.378 ENSMUST00000046520.6
Fkbp14
FK506 binding protein 14
chr18_+_12741324 0.375 ENSMUST00000115857.2
ENSMUST00000121018.1
ENSMUST00000119108.1
Cabyr


calcium-binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2)


chr17_-_57087729 0.374 ENSMUST00000071135.5
Tubb4a
tubulin, beta 4A class IVA
chr7_-_100583072 0.372 ENSMUST00000152876.1
ENSMUST00000150042.1
Mrpl48

mitochondrial ribosomal protein L48

chr3_+_103575231 0.366 ENSMUST00000121834.1
Syt6
synaptotagmin VI
chr2_-_34826071 0.365 ENSMUST00000113077.1
ENSMUST00000028220.3
Fbxw2

F-box and WD-40 domain protein 2

chr19_-_40588374 0.362 ENSMUST00000175932.1
ENSMUST00000176955.1
ENSMUST00000149476.2
Aldh18a1


aldehyde dehydrogenase 18 family, member A1


chr9_+_122351723 0.360 ENSMUST00000111497.3
Abhd5
abhydrolase domain containing 5
chr6_+_116650674 0.354 ENSMUST00000067354.5
ENSMUST00000178241.1
8430408G22Rik

RIKEN cDNA 8430408G22 gene

chr6_+_47920476 0.353 ENSMUST00000009411.8
Zfp212
Zinc finger protein 212
chr10_+_103367748 0.350 ENSMUST00000074204.4
ENSMUST00000179636.1
Slc6a15

solute carrier family 6 (neurotransmitter transporter), member 15

chr17_+_74395607 0.349 ENSMUST00000179074.1
ENSMUST00000024870.6
Slc30a6

solute carrier family 30 (zinc transporter), member 6

chr5_-_43981757 0.341 ENSMUST00000061299.7
Fgfbp1
fibroblast growth factor binding protein 1
chr7_+_79273201 0.339 ENSMUST00000037315.6
Abhd2
abhydrolase domain containing 2
chrX_-_75416533 0.338 ENSMUST00000033542.4
Mtcp1
mature T cell proliferation 1
chr2_-_144550777 0.336 ENSMUST00000028915.5
Rbbp9
retinoblastoma binding protein 9
chr1_+_34801704 0.336 ENSMUST00000047664.9
Arhgef4
Rho guanine nucleotide exchange factor (GEF) 4
chr2_+_32606946 0.332 ENSMUST00000113290.1
St6galnac6
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr1_-_134955908 0.329 ENSMUST00000045665.6
ENSMUST00000086444.4
ENSMUST00000112163.1
Ppp1r12b


protein phosphatase 1, regulatory (inhibitor) subunit 12B


chr2_-_29787622 0.327 ENSMUST00000177467.1
ENSMUST00000113807.3
Trub2

TruB pseudouridine (psi) synthase homolog 2 (E. coli)

chr3_+_121291725 0.326 ENSMUST00000039442.7
Alg14
asparagine-linked glycosylation 14
chr19_-_57182293 0.321 ENSMUST00000133369.1
Ablim1
actin-binding LIM protein 1
chr13_+_21478907 0.317 ENSMUST00000062609.5
Zkscan4
zinc finger with KRAB and SCAN domains 4
chr4_-_42661893 0.316 ENSMUST00000108006.3
Il11ra2
interleukin 11 receptor, alpha chain 2
chr4_+_110397661 0.315 ENSMUST00000106589.2
ENSMUST00000106587.2
ENSMUST00000106591.1
ENSMUST00000106592.1
Agbl4



ATP/GTP binding protein-like 4



chr2_+_32606979 0.313 ENSMUST00000113289.1
ENSMUST00000095044.3
St6galnac6

ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

chr15_+_8968389 0.311 ENSMUST00000053308.9
ENSMUST00000166524.1
Ranbp3l

RAN binding protein 3-like

chrX_-_162565514 0.311 ENSMUST00000154424.1
Reps2
RALBP1 associated Eps domain containing protein 2
chr3_+_159839729 0.309 ENSMUST00000068952.5
Wls
wntless homolog (Drosophila)
chrM_-_14060 0.306 ENSMUST00000082419.1
mt-Nd6
mitochondrially encoded NADH dehydrogenase 6
chr13_+_118714678 0.305 ENSMUST00000022246.8
Fgf10
fibroblast growth factor 10
chr13_-_62371936 0.302 ENSMUST00000107989.3
Gm3604
predicted gene 3604
chr19_+_8802486 0.302 ENSMUST00000172175.1
Zbtb3
zinc finger and BTB domain containing 3
chr12_-_85824506 0.302 ENSMUST00000021676.5
ENSMUST00000142331.1
0610007P14Rik

RIKEN cDNA 0610007P14 gene

chr19_+_46396885 0.301 ENSMUST00000039922.6
ENSMUST00000111867.2
ENSMUST00000120778.1
Sufu


suppressor of fused homolog (Drosophila)


chr13_-_29855630 0.295 ENSMUST00000091674.5
ENSMUST00000006353.7
Cdkal1

CDK5 regulatory subunit associated protein 1-like 1

chr9_-_95750335 0.293 ENSMUST00000053785.3
Trpc1
transient receptor potential cation channel, subfamily C, member 1
chrX_+_153139941 0.293 ENSMUST00000039720.4
ENSMUST00000144175.2
Rragb

Ras-related GTP binding B

chr1_+_58795371 0.290 ENSMUST00000027189.8
Casp8
caspase 8
chr7_+_44896077 0.290 ENSMUST00000071207.7
ENSMUST00000166849.1
ENSMUST00000168712.1
ENSMUST00000168389.1
Fuz



fuzzy homolog (Drosophila)



chr10_+_116177351 0.290 ENSMUST00000155606.1
ENSMUST00000128399.1
Ptprr

protein tyrosine phosphatase, receptor type, R

chr1_-_38821215 0.287 ENSMUST00000039612.4
Lonrf2
LON peptidase N-terminal domain and ring finger 2
chr19_+_8735808 0.285 ENSMUST00000049424.9
Wdr74
WD repeat domain 74
chr8_-_86580664 0.283 ENSMUST00000131423.1
ENSMUST00000152438.1
Abcc12

ATP-binding cassette, sub-family C (CFTR/MRP), member 12

chr1_-_134955847 0.281 ENSMUST00000168381.1
Ppp1r12b
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr2_-_150255591 0.277 ENSMUST00000063463.5
Gm21994
predicted gene 21994
chr14_+_118787894 0.276 ENSMUST00000047761.6
ENSMUST00000071546.7
Cldn10

claudin 10

chr2_-_140066661 0.276 ENSMUST00000046656.2
ENSMUST00000099304.3
ENSMUST00000110079.2
Tasp1


taspase, threonine aspartase 1


chr7_-_13054665 0.275 ENSMUST00000182515.1
ENSMUST00000069289.8
Mzf1

myeloid zinc finger 1

chr2_+_68104671 0.271 ENSMUST00000042456.3
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr13_+_104229366 0.271 ENSMUST00000022227.6
Cenpk
centromere protein K
chr15_+_25773985 0.270 ENSMUST00000125667.1
Myo10
myosin X
chr5_-_137600650 0.270 ENSMUST00000111007.1
ENSMUST00000133705.1
Mospd3

motile sperm domain containing 3

chr12_+_80644212 0.270 ENSMUST00000085245.5
Slc39a9
solute carrier family 39 (zinc transporter), member 9
chr7_+_45062429 0.270 ENSMUST00000107830.1
ENSMUST00000003513.3
ENSMUST00000107829.1
ENSMUST00000150609.1
Nosip



nitric oxide synthase interacting protein



chr16_+_11406618 0.266 ENSMUST00000122168.1
Snx29
sorting nexin 29
chr18_-_37969742 0.265 ENSMUST00000166148.1
ENSMUST00000163131.1
ENSMUST00000043437.7
Fchsd1


FCH and double SH3 domains 1


chr12_-_98259416 0.263 ENSMUST00000021390.7
Galc
galactosylceramidase
chr10_-_112928974 0.260 ENSMUST00000099276.2
Atxn7l3b
ataxin 7-like 3B
chr19_-_40588338 0.258 ENSMUST00000176939.1
Aldh18a1
aldehyde dehydrogenase 18 family, member A1
chr8_+_84990585 0.257 ENSMUST00000064495.6
Hook2
hook homolog 2 (Drosophila)
chr19_+_31082841 0.256 ENSMUST00000066039.6
Cstf2t
cleavage stimulation factor, 3' pre-RNA subunit 2, tau
chr7_-_133702515 0.255 ENSMUST00000153698.1
Uros
uroporphyrinogen III synthase
chr15_-_58034289 0.255 ENSMUST00000100655.3
9130401M01Rik
RIKEN cDNA 9130401M01 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 8.5 GO:0043490 malate-aspartate shuttle(GO:0043490)
1.0 4.1 GO:0032788 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.9 2.6 GO:0097212 lysosomal membrane organization(GO:0097212)
0.8 2.5 GO:0046110 xanthine metabolic process(GO:0046110)
0.8 2.5 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.6 2.9 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.5 1.5 GO:2000040 regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.4 2.1 GO:0006538 glutamate catabolic process(GO:0006538)
0.4 1.1 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.3 2.2 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.3 0.8 GO:2000314 negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.3 0.8 GO:0072592 oxygen metabolic process(GO:0072592)
0.2 0.6 GO:0006592 ornithine biosynthetic process(GO:0006592)
0.2 0.6 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.2 1.0 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.2 0.6 GO:2000564 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.2 1.3 GO:0019532 oxalate transport(GO:0019532)
0.2 0.9 GO:0072235 distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235)
0.2 2.2 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 0.6 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.2 0.5 GO:0002554 serotonin secretion by platelet(GO:0002554) interleukin-3 production(GO:0032632) beta selection(GO:0043366)
0.2 1.3 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.2 1.1 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 0.4 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.1 0.4 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.6 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.1 0.4 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.1 0.4 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.5 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.1 0.6 GO:0046208 spermine catabolic process(GO:0046208)
0.1 0.5 GO:0006041 glucosamine metabolic process(GO:0006041)
0.1 1.2 GO:0015824 proline transport(GO:0015824)
0.1 0.5 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.1 1.1 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.1 2.1 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.1 1.0 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.8 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.1 0.4 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.1 0.3 GO:0061357 Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356) positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.3 GO:0071336 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.1 1.0 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 0.8 GO:0071420 cellular response to histamine(GO:0071420)
0.1 0.6 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 0.4 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891) positive regulation of triglyceride catabolic process(GO:0010898)
0.1 0.5 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.1 0.4 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 0.2 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 0.2 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.1 1.6 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.7 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 0.3 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 0.6 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.3 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.1 0.5 GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.1 0.5 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.5 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1 1.4 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 1.6 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.3 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780)
0.1 0.4 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.1 0.3 GO:0061743 motor learning(GO:0061743)
0.1 3.4 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 1.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 0.7 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 0.2 GO:0061738 abscission(GO:0009838) late endosomal microautophagy(GO:0061738) positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 0.6 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.2 GO:0001692 histamine metabolic process(GO:0001692) imidazole-containing compound catabolic process(GO:0052805)
0.1 0.3 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.4 GO:0040031 snRNA modification(GO:0040031)
0.0 0.5 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.5 GO:0051923 sulfation(GO:0051923)
0.0 0.5 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.7 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.0 0.1 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.3 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.6 GO:0030497 fatty acid elongation(GO:0030497)
0.0 2.6 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.1 GO:0031038 myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519)
0.0 0.5 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.3 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 0.5 GO:0006681 galactosylceramide metabolic process(GO:0006681) galactolipid metabolic process(GO:0019374)
0.0 0.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.1 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.0 0.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 1.1 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.0 0.1 GO:0000389 generation of catalytic spliceosome for second transesterification step(GO:0000350) mRNA 3'-splice site recognition(GO:0000389)
0.0 0.3 GO:0046541 saliva secretion(GO:0046541)
0.0 2.4 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.2 GO:0097186 amelogenesis(GO:0097186)
0.0 0.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.3 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.5 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.3 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.3 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 1.4 GO:0006821 chloride transport(GO:0006821)
0.0 0.2 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.1 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.2 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.1 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0 0.1 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.4 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.2 GO:0036159 outer dynein arm assembly(GO:0036158) inner dynein arm assembly(GO:0036159)
0.0 0.5 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 0.1 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.2 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:0061622 glycolytic process through glucose-1-phosphate(GO:0061622)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.4 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.0 GO:0060527 prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.0 0.1 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361) termination of RNA polymerase I transcription(GO:0006363)
0.0 0.0 GO:0019085 early viral transcription(GO:0019085)
0.0 0.0 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
0.0 0.8 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.3 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 1.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.9 GO:0031076 embryonic camera-type eye development(GO:0031076)
0.0 0.1 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.0 0.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.2 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.3 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.0 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.0 0.1 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) phosphate ion transmembrane transport(GO:0035435) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.3 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.4 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.8 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.4 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.1 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.2 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0001674 female germ cell nucleus(GO:0001674)
0.2 0.8 GO:0071438 invadopodium membrane(GO:0071438)
0.2 2.5 GO:0042581 specific granule(GO:0042581)
0.1 1.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.4 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 0.5 GO:0019815 B cell receptor complex(GO:0019815)
0.1 1.0 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 2.6 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.3 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.1 3.9 GO:0034707 chloride channel complex(GO:0034707)
0.1 2.2 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 1.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 7.3 GO:0031594 neuromuscular junction(GO:0031594)
0.1 0.6 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 0.3 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.6 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.4 GO:0033269 internode region of axon(GO:0033269)
0.0 0.5 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.3 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.2 GO:0097443 sorting endosome(GO:0097443)
0.0 8.7 GO:0043197 dendritic spine(GO:0043197)
0.0 1.0 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.6 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.3 GO:0070695 FHF complex(GO:0070695)
0.0 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.2 GO:0042629 mast cell granule(GO:0042629)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.2 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.3 GO:0009986 cell surface(GO:0009986)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 1.0 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)
0.0 0.2 GO:0034709 methylosome(GO:0034709)
0.0 0.2 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.9 GO:0045171 intercellular bridge(GO:0045171)
0.0 2.9 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.6 GO:0031672 A band(GO:0031672)
0.0 0.3 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.1 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.2 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.5 GO:0016235 aggresome(GO:0016235)
0.0 0.6 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 1.2 GO:0000922 spindle pole(GO:0000922)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 7.9 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.8 2.5 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.6 2.5 GO:0030151 molybdenum ion binding(GO:0030151)
0.6 1.9 GO:0016748 succinyltransferase activity(GO:0016748)
0.4 2.9 GO:0001849 complement component C1q binding(GO:0001849)
0.4 1.2 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.3 2.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.3 1.4 GO:0019770 IgG receptor activity(GO:0019770)
0.3 0.8 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.3 0.8 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.3 1.0 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.2 4.0 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.2 1.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 0.6 GO:0017084 glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)
0.2 0.6 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.2 1.0 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.2 0.6 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.2 0.8 GO:0004966 galanin receptor activity(GO:0004966)
0.2 0.5 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.1 1.2 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 0.4 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 0.6 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.8 GO:1904315 GABA-gated chloride ion channel activity(GO:0022851) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 0.5 GO:0004074 biliverdin reductase activity(GO:0004074)
0.1 1.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 1.6 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 1.3 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.1 1.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.6 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.6 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.5 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 0.3 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.2 GO:0052740 phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 0.6 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 0.3 GO:0035877 death effector domain binding(GO:0035877)
0.1 0.3 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 0.5 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 2.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.5 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 0.5 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 0.2 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 2.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 1.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.6 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.6 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.2 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.3 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.8 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0051378 primary amine oxidase activity(GO:0008131) serotonin binding(GO:0051378)
0.0 0.5 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0071568 UFM1 transferase activity(GO:0071568)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.3 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.2 GO:0071253 connexin binding(GO:0071253)
0.0 0.2 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 1.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.2 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.4 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386) potassium ion antiporter activity(GO:0022821)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.7 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.0 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.0 0.1 GO:0009374 biotin binding(GO:0009374)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.1 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.0 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.5 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 1.1 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 0.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.9 GO:0019842 vitamin binding(GO:0019842)
0.0 0.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.3 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.2 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.8 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.2 GO:0008170 N-methyltransferase activity(GO:0008170)
0.0 1.4 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.1 2.9 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.7 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 0.3 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.3 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.5 PID_NFKAPPAB_ATYPICAL_PATHWAY Atypical NF-kappaB pathway
0.0 1.3 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 1.2 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.8 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.5 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 1.0 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.0 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.0 0.4 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.8 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 0.8 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.8 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 0.2 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.5 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 2.7 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 2.8 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 7.0 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 2.6 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 0.5 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 0.8 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 0.1 REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 2.2 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.1 0.8 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.0 0.7 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.6 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.1 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 1.5 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 1.6 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 4.5 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.3 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.5 REACTOME_REGULATION_OF_SIGNALING_BY_CBL Genes involved in Regulation of signaling by CBL
0.0 0.6 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.4 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.3 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.4 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.3 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.6 REACTOME_ADP_SIGNALLING_THROUGH_P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.4 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.1 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.1 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.2 REACTOME_ENOS_ACTIVATION_AND_REGULATION Genes involved in eNOS activation and regulation
0.0 0.4 REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis