Motif ID: Zfhx3

Z-value: 1.025


Transcription factors associated with Zfhx3:

Gene SymbolEntrez IDGene Name
Zfhx3 ENSMUSG00000038872.8 Zfhx3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfhx3mm10_v2_chr8_+_108714644_108714644-0.361.9e-02Click!


Activity profile for motif Zfhx3.

activity profile for motif Zfhx3


Sorted Z-values histogram for motif Zfhx3

Sorted Z-values for motif Zfhx3



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfhx3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_101377897 10.232 ENSMUST00000075994.6
Pdzrn3
PDZ domain containing RING finger 3
chr13_-_110280103 6.234 ENSMUST00000167824.1
Rab3c
RAB3C, member RAS oncogene family
chr10_-_110000219 5.657 ENSMUST00000032719.7
Nav3
neuron navigator 3
chrX_-_143933089 5.301 ENSMUST00000087313.3
Dcx
doublecortin
chr9_+_86485407 4.463 ENSMUST00000034987.8
Dopey1
dopey family member 1
chr17_+_35076902 3.749 ENSMUST00000172494.1
ENSMUST00000172678.1
ENSMUST00000013910.4
Ly6g6e


lymphocyte antigen 6 complex, locus G6E


chr2_+_82053222 3.512 ENSMUST00000047527.7
Zfp804a
zinc finger protein 804A
chrX_-_143933204 3.498 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chr1_+_179961110 3.418 ENSMUST00000076687.5
ENSMUST00000097450.3
Cdc42bpa

CDC42 binding protein kinase alpha

chr5_+_107497718 3.310 ENSMUST00000112671.2
A830010M20Rik
RIKEN cDNA A830010M20 gene
chr3_+_28263205 3.203 ENSMUST00000159236.2
Tnik
TRAF2 and NCK interacting kinase
chr4_-_32923455 3.021 ENSMUST00000035719.4
ENSMUST00000084749.1
Ankrd6

ankyrin repeat domain 6

chr16_-_74411776 3.014 ENSMUST00000116586.2
Robo2
roundabout homolog 2 (Drosophila)
chr1_-_158814469 2.850 ENSMUST00000161589.2
Pappa2
pappalysin 2
chr2_-_63184253 2.699 ENSMUST00000075052.3
ENSMUST00000112454.1
Kcnh7

potassium voltage-gated channel, subfamily H (eag-related), member 7

chr5_+_107497762 2.607 ENSMUST00000152474.1
ENSMUST00000060553.7
A830010M20Rik

RIKEN cDNA A830010M20 gene

chr1_-_24612700 2.567 ENSMUST00000088336.1
Gm10222
predicted gene 10222
chr14_+_64588112 2.496 ENSMUST00000181808.1
A930011O12Rik
RIKEN cDNA A930011O12 gene
chr1_-_157256682 2.472 ENSMUST00000134543.1
Rasal2
RAS protein activator like 2
chr2_+_120977017 2.443 ENSMUST00000067582.7
Tmem62
transmembrane protein 62
chrM_+_9870 2.330 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr2_+_3770673 2.286 ENSMUST00000177037.1
Fam107b
family with sequence similarity 107, member B
chr9_+_113812547 2.240 ENSMUST00000166734.2
ENSMUST00000111838.2
ENSMUST00000163895.2
Clasp2


CLIP associating protein 2


chr5_-_107875035 2.111 ENSMUST00000138111.1
ENSMUST00000112642.1
Evi5

ecotropic viral integration site 5

chr2_-_63184170 2.055 ENSMUST00000112452.1
Kcnh7
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr18_+_37518341 2.006 ENSMUST00000097609.1
Pcdhb22
protocadherin beta 22
chr13_+_83732438 1.965 ENSMUST00000182701.1
C130071C03Rik
RIKEN cDNA C130071C03 gene
chrX_+_163911401 1.912 ENSMUST00000140845.1
Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr8_-_67818284 1.811 ENSMUST00000120071.1
Psd3
pleckstrin and Sec7 domain containing 3
chr10_+_115384951 1.708 ENSMUST00000036044.8
Zfc3h1
zinc finger, C3H1-type containing
chr1_+_179960472 1.692 ENSMUST00000097453.2
ENSMUST00000111117.1
Cdc42bpa

CDC42 binding protein kinase alpha

chr9_+_95857597 1.680 ENSMUST00000034980.7
Atr
ataxia telangiectasia and Rad3 related
chr10_-_56228636 1.673 ENSMUST00000099739.3
Tbc1d32
TBC1 domain family, member 32
chr9_+_54980880 1.504 ENSMUST00000093844.3
Chrna5
cholinergic receptor, nicotinic, alpha polypeptide 5
chr10_-_17947997 1.486 ENSMUST00000037879.6
Heca
headcase homolog (Drosophila)
chr10_+_23797052 1.486 ENSMUST00000133289.1
Slc18b1
solute carrier family 18, subfamily B, member 1
chr1_-_12991109 1.462 ENSMUST00000115403.2
ENSMUST00000115402.1
Slco5a1

solute carrier organic anion transporter family, member 5A1

chr3_+_66985680 1.435 ENSMUST00000065047.6
Rsrc1
arginine/serine-rich coiled-coil 1
chr5_+_25246775 1.434 ENSMUST00000144971.1
Galnt11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11
chr13_-_75943812 1.401 ENSMUST00000022078.5
ENSMUST00000109606.1
Rhobtb3

Rho-related BTB domain containing 3

chr6_+_127453667 1.325 ENSMUST00000112193.1
Parp11
poly (ADP-ribose) polymerase family, member 11
chr12_+_71170589 1.256 ENSMUST00000129376.1
2700049A03Rik
RIKEN cDNA 2700049A03 gene
chr4_+_101507947 1.232 ENSMUST00000149047.1
ENSMUST00000106929.3
Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr19_+_10015016 1.206 ENSMUST00000137637.1
ENSMUST00000149967.1
Rab3il1

RAB3A interacting protein (rabin3)-like 1

chr10_+_23796946 1.193 ENSMUST00000119597.1
ENSMUST00000179321.1
Slc18b1

solute carrier family 18, subfamily B, member 1

chrM_+_7759 1.120 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr6_-_122340499 1.111 ENSMUST00000160843.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr2_+_177768044 1.093 ENSMUST00000108942.3
Gm14322
predicted gene 14322
chrM_+_14138 1.036 ENSMUST00000082421.1
mt-Cytb
mitochondrially encoded cytochrome b
chr8_-_9976294 1.033 ENSMUST00000095476.4
Lig4
ligase IV, DNA, ATP-dependent
chr2_-_37647199 0.983 ENSMUST00000028279.3
Strbp
spermatid perinuclear RNA binding protein
chr3_+_76075583 0.893 ENSMUST00000160261.1
Fstl5
follistatin-like 5
chr11_+_24078173 0.846 ENSMUST00000109514.1
Bcl11a
B cell CLL/lymphoma 11A (zinc finger protein)
chr8_+_47713266 0.822 ENSMUST00000180928.1
E030037K01Rik
RIKEN cDNA E030037K01 gene
chr7_+_55794146 0.810 ENSMUST00000032627.3
Tubgcp5
tubulin, gamma complex associated protein 5
chr18_+_55057557 0.772 ENSMUST00000181765.1
Gm4221
predicted gene 4221
chr3_+_90537306 0.747 ENSMUST00000107335.1
S100a16
S100 calcium binding protein A16
chr3_+_90537242 0.718 ENSMUST00000098911.3
S100a16
S100 calcium binding protein A16
chr6_-_38124568 0.700 ENSMUST00000040259.4
Atp6v0a4
ATPase, H+ transporting, lysosomal V0 subunit A4
chr1_-_126830632 0.695 ENSMUST00000112583.1
ENSMUST00000094609.3
Nckap5

NCK-associated protein 5

chr7_-_34655500 0.683 ENSMUST00000032709.1
Kctd15
potassium channel tetramerisation domain containing 15
chr1_+_74661794 0.679 ENSMUST00000129890.1
Ttll4
tubulin tyrosine ligase-like family, member 4
chr8_+_83666827 0.620 ENSMUST00000019608.5
Ptger1
prostaglandin E receptor 1 (subtype EP1)
chr10_+_79927330 0.619 ENSMUST00000105376.1
Arid3a
AT rich interactive domain 3A (BRIGHT-like)
chr10_+_79927039 0.618 ENSMUST00000019708.5
ENSMUST00000105377.1
Arid3a

AT rich interactive domain 3A (BRIGHT-like)

chr6_-_86765866 0.603 ENSMUST00000113675.1
Anxa4
annexin A4
chr1_-_132390301 0.597 ENSMUST00000132435.1
Tmcc2
transmembrane and coiled-coil domains 2
chr2_-_140671440 0.581 ENSMUST00000099301.1
Flrt3
fibronectin leucine rich transmembrane protein 3
chr2_-_120245157 0.579 ENSMUST00000090071.4
Pla2g4e
phospholipase A2, group IVE
chr5_+_24394388 0.578 ENSMUST00000115074.1
Abcb8
ATP-binding cassette, sub-family B (MDR/TAP), member 8
chr17_-_32886083 0.568 ENSMUST00000178401.1
Zfp870
zinc finger protein 870
chr17_-_50094277 0.567 ENSMUST00000113195.1
Rftn1
raftlin lipid raft linker 1
chr8_-_67818218 0.555 ENSMUST00000059374.4
Psd3
pleckstrin and Sec7 domain containing 3
chr11_+_24078022 0.555 ENSMUST00000000881.6
Bcl11a
B cell CLL/lymphoma 11A (zinc finger protein)
chr12_-_12941827 0.552 ENSMUST00000043396.7
Mycn
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr9_-_22208546 0.527 ENSMUST00000167359.1
1810064F22Rik
RIKEN cDNA 1810064F22 gene
chr9_+_55326913 0.480 ENSMUST00000085754.3
ENSMUST00000034862.4
AI118078

expressed sequence AI118078

chr9_-_120068263 0.474 ENSMUST00000064165.3
ENSMUST00000177637.1
Cx3cr1

chemokine (C-X3-C) receptor 1

chr12_-_27160311 0.466 ENSMUST00000182473.1
ENSMUST00000177636.1
ENSMUST00000183238.1
Gm9866


predicted gene 9866


chr2_-_165368723 0.447 ENSMUST00000141140.1
ENSMUST00000103085.1
Zfp663

zinc finger protein 663

chr3_+_136670076 0.413 ENSMUST00000070198.7
Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr6_-_86765807 0.406 ENSMUST00000123732.1
Anxa4
annexin A4
chr1_-_168432270 0.297 ENSMUST00000072863.4
Pbx1
pre B cell leukemia homeobox 1
chrX_-_111536325 0.297 ENSMUST00000156639.1
Rps6ka6
ribosomal protein S6 kinase polypeptide 6
chr1_-_126830786 0.252 ENSMUST00000162646.1
Nckap5
NCK-associated protein 5
chr15_+_31224371 0.232 ENSMUST00000044524.9
Dap
death-associated protein
chr1_+_172698046 0.218 ENSMUST00000038495.3
Crp
C-reactive protein, pentraxin-related
chr5_-_43981757 0.204 ENSMUST00000061299.7
Fgfbp1
fibroblast growth factor binding protein 1
chr4_+_150853919 0.199 ENSMUST00000073600.2
Errfi1
ERBB receptor feedback inhibitor 1
chr1_+_164275559 0.181 ENSMUST00000027867.6
Ccdc181
coiled-coil domain containing 181
chr15_+_102459028 0.172 ENSMUST00000164938.1
ENSMUST00000023810.5
Prr13

proline rich 13

chr5_-_38491948 0.141 ENSMUST00000129099.1
Slc2a9
solute carrier family 2 (facilitated glucose transporter), member 9
chr8_+_93810832 0.134 ENSMUST00000034198.8
ENSMUST00000125716.1
Gnao1

guanine nucleotide binding protein, alpha O

chr2_-_140671400 0.129 ENSMUST00000056760.3
Flrt3
fibronectin leucine rich transmembrane protein 3
chr11_+_4986824 0.127 ENSMUST00000009234.9
ENSMUST00000109897.1
Ap1b1

adaptor protein complex AP-1, beta 1 subunit

chrM_+_2743 0.123 ENSMUST00000082392.1
mt-Nd1
mitochondrially encoded NADH dehydrogenase 1
chr3_+_66985647 0.104 ENSMUST00000162362.1
ENSMUST00000065074.7
Rsrc1

arginine/serine-rich coiled-coil 1

chr15_+_102459193 0.093 ENSMUST00000164957.1
ENSMUST00000171245.1
Prr13

proline rich 13

chr19_+_48206025 0.042 ENSMUST00000078880.5
Sorcs3
sortilin-related VPS10 domain containing receptor 3
chr2_-_121235689 0.024 ENSMUST00000142400.1
Trp53bp1
transformation related protein 53 binding protein 1
chr11_+_24078111 0.020 ENSMUST00000109516.1
Bcl11a
B cell CLL/lymphoma 11A (zinc finger protein)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.7 10.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.6 3.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.6 1.7 GO:1904884 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.3 2.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.3 1.7 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.3 4.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.2 1.0 GO:0033762 response to glucagon(GO:0033762)
0.2 1.2 GO:0072318 clathrin coat disassembly(GO:0072318)
0.2 1.4 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.2 1.0 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.2 3.0 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.2 5.1 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.2 1.0 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.2 10.2 GO:0007528 neuromuscular junction development(GO:0007528)
0.2 1.5 GO:0035095 behavioral response to nicotine(GO:0035095)
0.2 3.7 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.1 0.4 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) regulation of connective tissue replacement(GO:1905203)
0.1 0.4 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.1 0.8 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1 0.6 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.1 1.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 0.5 GO:0002677 negative regulation of chronic inflammatory response(GO:0002677)
0.1 2.4 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.7 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.7 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 6.2 GO:0019882 antigen processing and presentation(GO:0019882)
0.1 0.2 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0 1.1 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 3.5 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 2.5 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.0 1.5 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.2 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 1.9 GO:0060612 adipose tissue development(GO:0060612)
0.0 1.9 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.2 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 1.0 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.6 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.0 4.8 GO:0051291 protein heterooligomerization(GO:0051291)
0.0 1.3 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 1.1 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.3 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.1 GO:0046415 urate metabolic process(GO:0046415)
0.0 2.3 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.6 GO:0009395 phospholipid catabolic process(GO:0009395)
0.0 0.3 GO:0030325 adrenal gland development(GO:0030325)
0.0 1.5 GO:0051592 response to calcium ion(GO:0051592)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.2 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.2 0.8 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.2 2.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2 1.0 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.1 1.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 1.1 GO:0001739 sex chromatin(GO:0001739)
0.1 10.2 GO:0031594 neuromuscular junction(GO:0031594)
0.1 0.7 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 1.0 GO:0045275 respiratory chain complex III(GO:0045275)
0.1 3.0 GO:0030673 axolemma(GO:0030673)
0.1 1.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.4 GO:0005955 calcineurin complex(GO:0005955)
0.1 1.7 GO:0001741 XY body(GO:0001741)
0.1 2.0 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 2.4 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 5.1 GO:0042641 actomyosin(GO:0042641)
0.0 9.4 GO:0030426 growth cone(GO:0030426)
0.0 6.2 GO:0008021 synaptic vesicle(GO:0008021)
0.0 1.5 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 3.2 GO:0055037 recycling endosome(GO:0055037)
0.0 1.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 4.6 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.2 GO:0002177 manchette(GO:0002177)
0.0 8.1 GO:0005635 nuclear envelope(GO:0005635)
0.0 0.5 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 1.3 GO:0005814 centriole(GO:0005814)
0.0 2.7 GO:0014069 postsynaptic density(GO:0014069)
0.0 1.8 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.3 3.0 GO:0008046 axon guidance receptor activity(GO:0008046)
0.3 1.7 GO:0032405 MutLalpha complex binding(GO:0032405) MutSalpha complex binding(GO:0032407)
0.3 6.2 GO:0031489 myosin V binding(GO:0031489)
0.2 4.8 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.2 3.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 1.0 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.2 2.2 GO:0002162 dystroglycan binding(GO:0002162)
0.2 1.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 1.5 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 1.0 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.6 GO:0004954 icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)
0.1 0.5 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.1 0.7 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.1 0.8 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 1.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 2.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 1.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.4 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.7 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 10.2 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 2.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 1.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.6 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.4 GO:0045499 chemorepellent activity(GO:0045499)
0.0 1.0 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 7.3 GO:0008017 microtubule binding(GO:0008017)
0.0 3.5 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 5.4 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821) corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 1.5 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 2.0 GO:0008565 protein transporter activity(GO:0008565)
0.0 1.2 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 2.5 GO:0005096 GTPase activator activity(GO:0005096)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 8.8 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 1.7 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.1 3.0 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.1 3.2 PID_TNF_PATHWAY TNF receptor signaling pathway
0.1 5.1 PID_CDC42_PATHWAY CDC42 signaling events
0.0 2.1 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 1.0 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 2.9 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 0.1 PID_S1P_S1P4_PATHWAY S1P4 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.2 1.5 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.2 2.9 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 1.7 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 2.0 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 4.8 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 0.8 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 1.2 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 3.0 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.1 9.1 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions
0.1 1.0 REACTOME_INTEGRATION_OF_PROVIRUS Genes involved in Integration of provirus
0.0 0.2 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 1.4 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.7 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.5 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.1 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters