Motif ID: Plag1

Z-value: 0.582


Transcription factors associated with Plag1:

Gene SymbolEntrez IDGene Name
Plag1 ENSMUSG00000003282.3 Plag1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Plag1mm10_v2_chr4_-_3938354_3938401-0.315.1e-02Click!


Activity profile for motif Plag1.

activity profile for motif Plag1


Sorted Z-values histogram for motif Plag1

Sorted Z-values for motif Plag1



Network of associatons between targets according to the STRING database.



First level regulatory network of Plag1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_133498538 2.580 ENSMUST00000125541.1
Trnp1
TMF1-regulated nuclear protein 1
chr18_-_58209926 1.999 ENSMUST00000025497.6
Fbn2
fibrillin 2
chr4_-_129121699 1.891 ENSMUST00000135763.1
ENSMUST00000149763.1
ENSMUST00000164649.1
Hpca


hippocalcin


chr5_+_117841839 1.811 ENSMUST00000142742.2
Nos1
nitric oxide synthase 1, neuronal
chr10_-_102490418 1.632 ENSMUST00000020040.3
Nts
neurotensin
chr15_-_66801577 1.618 ENSMUST00000168589.1
Sla
src-like adaptor
chr5_+_117781017 1.358 ENSMUST00000138579.2
Nos1
nitric oxide synthase 1, neuronal
chr11_-_69369377 1.347 ENSMUST00000092971.6
ENSMUST00000108661.1
Chd3

chromodomain helicase DNA binding protein 3

chr1_-_56969864 1.305 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr4_-_129121234 1.275 ENSMUST00000030572.3
Hpca
hippocalcin
chr4_-_129121889 1.198 ENSMUST00000139450.1
ENSMUST00000125931.1
ENSMUST00000116444.2
Hpca


hippocalcin


chr7_-_27446599 1.172 ENSMUST00000011895.7
Sptbn4
spectrin beta, non-erythrocytic 4
chr7_-_46099752 1.161 ENSMUST00000180081.1
Kcnj11
potassium inwardly rectifying channel, subfamily J, member 11
chr5_-_89883321 1.137 ENSMUST00000163159.1
ENSMUST00000061427.5
Adamts3

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 3

chr3_+_89520152 1.122 ENSMUST00000000811.7
Kcnn3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr7_-_46179929 1.085 ENSMUST00000033123.6
Abcc8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr1_-_56969827 1.056 ENSMUST00000176759.1
Satb2
special AT-rich sequence binding protein 2
chr3_+_117575268 1.012 ENSMUST00000039564.6
4833424O15Rik
RIKEN cDNA 4833424O15 gene
chr1_+_75382114 1.005 ENSMUST00000113590.1
ENSMUST00000148515.1
Speg

SPEG complex locus

chr5_-_37717122 0.972 ENSMUST00000094836.4
Stk32b
serine/threonine kinase 32B
chr4_+_130308595 0.954 ENSMUST00000070532.7
Fabp3
fatty acid binding protein 3, muscle and heart
chr19_-_42431778 0.950 ENSMUST00000048630.6
Crtac1
cartilage acidic protein 1
chr17_-_87797994 0.924 ENSMUST00000055221.7
Kcnk12
potassium channel, subfamily K, member 12
chr15_-_78544345 0.920 ENSMUST00000053239.2
Sstr3
somatostatin receptor 3
chr1_-_56972437 0.862 ENSMUST00000042857.7
Satb2
special AT-rich sequence binding protein 2
chrX_+_94234594 0.861 ENSMUST00000153900.1
Klhl15
kelch-like 15
chr15_-_99528017 0.860 ENSMUST00000023750.7
Faim2
Fas apoptotic inhibitory molecule 2
chr11_-_67922136 0.857 ENSMUST00000021288.3
ENSMUST00000108677.1
Usp43

ubiquitin specific peptidase 43

chr12_-_4841583 0.857 ENSMUST00000020964.5
Fkbp1b
FK506 binding protein 1b
chr19_-_59076069 0.836 ENSMUST00000047511.7
ENSMUST00000163821.1
4930506M07Rik

RIKEN cDNA 4930506M07 gene

chr9_+_50752758 0.835 ENSMUST00000034562.7
Cryab
crystallin, alpha B
chr14_+_80000292 0.821 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr7_-_27396542 0.813 ENSMUST00000108363.1
Sptbn4
spectrin beta, non-erythrocytic 4
chr1_+_159737510 0.800 ENSMUST00000111669.3
Tnr
tenascin R
chr11_+_77930800 0.797 ENSMUST00000093995.3
ENSMUST00000000646.7
Sez6

seizure related gene 6

chr16_-_85803106 0.794 ENSMUST00000023610.8
Adamts1
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1
chr17_-_24689901 0.792 ENSMUST00000007236.4
Syngr3
synaptogyrin 3
chr7_-_79386943 0.772 ENSMUST00000053718.8
ENSMUST00000179243.1
Rlbp1

retinaldehyde binding protein 1

chr6_-_148444336 0.762 ENSMUST00000060095.8
ENSMUST00000100772.3
Tmtc1

transmembrane and tetratricopeptide repeat containing 1

chr16_-_18622403 0.754 ENSMUST00000167388.1
Gp1bb
glycoprotein Ib, beta polypeptide
chr13_-_14523178 0.735 ENSMUST00000110516.2
Hecw1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chrX_+_8271133 0.722 ENSMUST00000127103.1
ENSMUST00000115591.1
Slc38a5

solute carrier family 38, member 5

chr6_-_85502858 0.716 ENSMUST00000161546.1
ENSMUST00000161078.1
Fbxo41

F-box protein 41

chr11_-_120047070 0.713 ENSMUST00000064307.3
Aatk
apoptosis-associated tyrosine kinase
chr6_+_55836878 0.694 ENSMUST00000044729.6
Ccdc129
coiled-coil domain containing 129
chr11_+_74619594 0.684 ENSMUST00000100866.2
E130309D14Rik
RIKEN cDNA E130309D14 gene
chr2_-_32353247 0.678 ENSMUST00000078352.5
ENSMUST00000113352.2
ENSMUST00000113365.1
Dnm1


dynamin 1


chr10_+_58813359 0.674 ENSMUST00000135526.2
ENSMUST00000153031.1
Sh3rf3

SH3 domain containing ring finger 3

chr15_-_75566811 0.673 ENSMUST00000065417.8
Ly6h
lymphocyte antigen 6 complex, locus H
chr11_-_76509419 0.662 ENSMUST00000094012.4
Abr
active BCR-related gene
chr6_-_101377897 0.639 ENSMUST00000075994.6
Pdzrn3
PDZ domain containing RING finger 3
chr5_+_75152274 0.635 ENSMUST00000000476.8
Pdgfra
platelet derived growth factor receptor, alpha polypeptide
chr10_-_81025521 0.634 ENSMUST00000144640.1
Diras1
DIRAS family, GTP-binding RAS-like 1
chr1_+_132880273 0.629 ENSMUST00000027706.3
Lrrn2
leucine rich repeat protein 2, neuronal
chr7_+_5057161 0.622 ENSMUST00000045543.5
Ccdc106
coiled-coil domain containing 106
chr3_+_117575227 0.621 ENSMUST00000106473.2
4833424O15Rik
RIKEN cDNA 4833424O15 gene
chr15_+_60822947 0.619 ENSMUST00000180730.1
9930014A18Rik
RIKEN cDNA 9930014A18 gene
chr6_-_124768330 0.611 ENSMUST00000135626.1
Eno2
enolase 2, gamma neuronal
chr14_-_49525840 0.610 ENSMUST00000138884.1
ENSMUST00000074368.4
ENSMUST00000123534.1
Slc35f4


solute carrier family 35, member F4


chr2_+_32646586 0.602 ENSMUST00000009705.7
ENSMUST00000167841.1
Eng

endoglin

chr9_+_40269273 0.592 ENSMUST00000176185.1
Scn3b
sodium channel, voltage-gated, type III, beta
chr19_+_8664005 0.585 ENSMUST00000035444.3
ENSMUST00000163785.1
Chrm1

cholinergic receptor, muscarinic 1, CNS

chr5_+_130448801 0.583 ENSMUST00000111288.2
Caln1
calneuron 1
chr10_-_109010955 0.579 ENSMUST00000105276.1
ENSMUST00000064054.7
Syt1

synaptotagmin I

chr11_-_102296618 0.570 ENSMUST00000107132.2
ENSMUST00000073234.2
Atxn7l3

ataxin 7-like 3

chr9_+_40269202 0.560 ENSMUST00000114956.3
ENSMUST00000049941.5
Scn3b

sodium channel, voltage-gated, type III, beta

chr7_-_141010759 0.558 ENSMUST00000026565.6
Ifitm3
interferon induced transmembrane protein 3
chr11_-_55033398 0.558 ENSMUST00000108883.3
ENSMUST00000102727.2
Anxa6

annexin A6

chr7_+_54835959 0.550 ENSMUST00000082373.6
Luzp2
leucine zipper protein 2
chr9_-_86880647 0.549 ENSMUST00000167014.1
Snap91
synaptosomal-associated protein 91
chrX_-_166585679 0.544 ENSMUST00000000412.2
Egfl6
EGF-like-domain, multiple 6
chr2_+_151702182 0.533 ENSMUST00000109872.1
Tmem74b
transmembrane protein 74b
chr1_-_43163891 0.531 ENSMUST00000008280.7
Fhl2
four and a half LIM domains 2
chr2_+_158666690 0.531 ENSMUST00000103116.3
Ppp1r16b
protein phosphatase 1, regulatory (inhibitor) subunit 16B
chr3_+_53041517 0.526 ENSMUST00000059562.7
ENSMUST00000147139.1
Lhfp

lipoma HMGIC fusion partner

chr11_+_70018421 0.525 ENSMUST00000108588.1
Dlg4
discs, large homolog 4 (Drosophila)
chr6_-_8778106 0.525 ENSMUST00000151758.1
ENSMUST00000115519.1
ENSMUST00000153390.1
Ica1


islet cell autoantigen 1


chr9_-_44288332 0.523 ENSMUST00000161408.1
Abcg4
ATP-binding cassette, sub-family G (WHITE), member 4
chr2_+_158667119 0.521 ENSMUST00000045503.4
Ppp1r16b
protein phosphatase 1, regulatory (inhibitor) subunit 16B
chr17_+_31386244 0.520 ENSMUST00000134525.1
ENSMUST00000127929.1
Pde9a

phosphodiesterase 9A

chr4_+_155734800 0.519 ENSMUST00000147721.1
ENSMUST00000127188.2
Tmem240

transmembrane protein 240

chr11_-_95587691 0.515 ENSMUST00000000122.6
Ngfr
nerve growth factor receptor (TNFR superfamily, member 16)
chr9_-_86880414 0.512 ENSMUST00000074501.5
ENSMUST00000098495.3
ENSMUST00000074468.6
ENSMUST00000036347.6
Snap91



synaptosomal-associated protein 91



chr18_-_38211957 0.509 ENSMUST00000159405.1
ENSMUST00000160721.1
Pcdh1

protocadherin 1

chr8_-_87472576 0.507 ENSMUST00000034076.8
Cbln1
cerebellin 1 precursor protein
chr10_+_127078886 0.495 ENSMUST00000039259.6
Agap2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr6_-_29507946 0.494 ENSMUST00000101614.3
ENSMUST00000078112.6
Kcp

kielin/chordin-like protein

chr9_+_37528071 0.493 ENSMUST00000002011.7
Esam
endothelial cell-specific adhesion molecule
chr17_+_37045963 0.492 ENSMUST00000025338.9
Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr12_+_87026564 0.486 ENSMUST00000110187.1
ENSMUST00000156162.1
Tmem63c

transmembrane protein 63c

chr11_-_72489904 0.485 ENSMUST00000045303.3
Spns2
spinster homolog 2
chr13_+_55152640 0.483 ENSMUST00000005452.5
Fgfr4
fibroblast growth factor receptor 4
chr4_+_101550411 0.471 ENSMUST00000094953.4
ENSMUST00000106933.1
Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr14_+_70553687 0.467 ENSMUST00000161069.1
Hr
hairless
chr12_-_70347536 0.463 ENSMUST00000110520.2
ENSMUST00000110522.2
ENSMUST00000167755.1
Trim9


tripartite motif-containing 9


chr2_+_121358591 0.463 ENSMUST00000000317.6
ENSMUST00000129130.1
Ckmt1

creatine kinase, mitochondrial 1, ubiquitous

chr9_-_21037775 0.455 ENSMUST00000180870.1
Gm26592
predicted gene, 26592
chr15_+_98632220 0.454 ENSMUST00000109150.1
Cacnb3
calcium channel, voltage-dependent, beta 3 subunit
chr2_-_92024502 0.451 ENSMUST00000028663.4
Creb3l1
cAMP responsive element binding protein 3-like 1
chr7_-_27674516 0.451 ENSMUST00000036453.7
ENSMUST00000108341.1
Map3k10

mitogen-activated protein kinase kinase kinase 10

chr15_+_101266839 0.449 ENSMUST00000023779.6
Nr4a1
nuclear receptor subfamily 4, group A, member 1
chr1_-_38836090 0.446 ENSMUST00000147695.1
Lonrf2
LON peptidase N-terminal domain and ring finger 2
chr16_-_28445227 0.442 ENSMUST00000100024.1
Fgf12
fibroblast growth factor 12
chr7_-_78578308 0.436 ENSMUST00000039431.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr14_-_20480106 0.436 ENSMUST00000065504.9
ENSMUST00000100844.4
Anxa7

annexin A7

chr7_-_4546567 0.432 ENSMUST00000065957.5
Syt5
synaptotagmin V
chr16_+_45093611 0.426 ENSMUST00000099498.2
Ccdc80
coiled-coil domain containing 80
chr18_-_24709348 0.424 ENSMUST00000067987.1
Gm9955
predicted gene 9955
chr11_+_78188737 0.424 ENSMUST00000108322.2
Rab34
RAB34, member of RAS oncogene family
chr9_-_40531362 0.422 ENSMUST00000119373.1
Gramd1b
GRAM domain containing 1B
chr17_+_37045980 0.419 ENSMUST00000174456.1
Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr2_-_27027909 0.418 ENSMUST00000102890.4
ENSMUST00000153388.1
ENSMUST00000045702.5
Slc2a6


solute carrier family 2 (facilitated glucose transporter), member 6


chr19_+_44989073 0.414 ENSMUST00000026225.8
Sema4g
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr15_+_73723131 0.413 ENSMUST00000165541.1
ENSMUST00000167582.1
Ptp4a3

protein tyrosine phosphatase 4a3

chr8_-_36249292 0.413 ENSMUST00000065297.5
Lonrf1
LON peptidase N-terminal domain and ring finger 1
chr10_+_103367748 0.410 ENSMUST00000074204.4
ENSMUST00000179636.1
Slc6a15

solute carrier family 6 (neurotransmitter transporter), member 15

chr7_+_126950518 0.409 ENSMUST00000106335.1
ENSMUST00000146017.1
Sez6l2

seizure related 6 homolog like 2

chr2_+_170731807 0.409 ENSMUST00000029075.4
Dok5
docking protein 5
chrX_+_73483602 0.408 ENSMUST00000033741.8
ENSMUST00000169489.1
Bgn

biglycan

chr17_-_66077022 0.405 ENSMUST00000150766.1
ENSMUST00000038116.5
Ankrd12

ankyrin repeat domain 12

chr11_-_120047144 0.404 ENSMUST00000103020.1
Aatk
apoptosis-associated tyrosine kinase
chr2_+_55437100 0.399 ENSMUST00000112633.2
ENSMUST00000112632.1
Kcnj3

potassium inwardly-rectifying channel, subfamily J, member 3

chr3_-_88000350 0.398 ENSMUST00000090971.5
Bcan
brevican
chr17_+_48932368 0.394 ENSMUST00000046254.2
Lrfn2
leucine rich repeat and fibronectin type III domain containing 2
chrX_+_159627534 0.391 ENSMUST00000073094.3
Sh3kbp1
SH3-domain kinase binding protein 1
chr11_+_94990996 0.390 ENSMUST00000038696.5
Ppp1r9b
protein phosphatase 1, regulatory subunit 9B
chr7_+_3303503 0.388 ENSMUST00000100301.4
Prkcg
protein kinase C, gamma
chr1_-_190979280 0.387 ENSMUST00000166139.1
Vash2
vasohibin 2
chr3_-_108017806 0.386 ENSMUST00000126593.1
Gstm1
glutathione S-transferase, mu 1
chr16_+_45094036 0.384 ENSMUST00000061050.5
Ccdc80
coiled-coil domain containing 80
chr6_-_8778439 0.382 ENSMUST00000115520.1
ENSMUST00000038403.5
ENSMUST00000115518.1
Ica1


islet cell autoantigen 1


chrX_+_73503074 0.381 ENSMUST00000114479.1
ENSMUST00000088429.1
ENSMUST00000033744.5
Atp2b3


ATPase, Ca++ transporting, plasma membrane 3


chr7_-_44375006 0.376 ENSMUST00000107933.1
1700008O03Rik
RIKEN cDNA 1700008O03 gene
chr7_+_126950687 0.375 ENSMUST00000106333.1
Sez6l2
seizure related 6 homolog like 2
chr1_+_75400070 0.374 ENSMUST00000113589.1
Speg
SPEG complex locus
chr15_+_99295087 0.374 ENSMUST00000128352.1
ENSMUST00000145482.1
Prpf40b

PRP40 pre-mRNA processing factor 40 homolog B (yeast)

chr5_+_37245792 0.372 ENSMUST00000031004.7
Crmp1
collapsin response mediator protein 1
chr9_+_54764748 0.371 ENSMUST00000034830.8
Crabp1
cellular retinoic acid binding protein I
chr8_-_95142477 0.367 ENSMUST00000034240.7
ENSMUST00000169748.1
Kifc3

kinesin family member C3

chr2_-_25621923 0.364 ENSMUST00000028308.4
ENSMUST00000142087.1
Tmem141

transmembrane protein 141

chr5_+_33995984 0.362 ENSMUST00000056355.8
Nat8l
N-acetyltransferase 8-like
chr17_+_37050631 0.361 ENSMUST00000172792.1
ENSMUST00000174347.1
Gabbr1

gamma-aminobutyric acid (GABA) B receptor, 1

chr6_-_82939676 0.360 ENSMUST00000000641.9
ENSMUST00000113982.1
Sema4f

sema domain, immunoglobulin domain (Ig), TM domain, and short cytoplasmic domain

chr17_-_45686899 0.360 ENSMUST00000156254.1
Tmem63b
transmembrane protein 63b
chrX_+_94234982 0.354 ENSMUST00000096369.3
ENSMUST00000113911.2
Klhl15

kelch-like 15

chr7_+_126950837 0.353 ENSMUST00000106332.1
Sez6l2
seizure related 6 homolog like 2
chr15_+_25414175 0.353 ENSMUST00000069992.5
Gm5468
predicted gene 5468
chr2_+_118779703 0.351 ENSMUST00000063975.3
ENSMUST00000037547.2
ENSMUST00000110846.1
ENSMUST00000110843.1
Disp2



dispatched homolog 2 (Drosophila)



chr2_-_153225396 0.350 ENSMUST00000099194.2
Tspyl3
TSPY-like 3
chr17_+_26941420 0.350 ENSMUST00000081285.3
ENSMUST00000177932.1
Syngap1

synaptic Ras GTPase activating protein 1 homolog (rat)

chrX_-_59134421 0.348 ENSMUST00000033473.5
Fgf13
fibroblast growth factor 13
chr8_+_3621529 0.348 ENSMUST00000156380.2
Pet100
PET100 homolog (S. cerevisiae)
chr12_+_81631369 0.346 ENSMUST00000036116.5
Ttc9
tetratricopeptide repeat domain 9
chrX_+_7919816 0.345 ENSMUST00000041096.3
Pcsk1n
proprotein convertase subtilisin/kexin type 1 inhibitor
chr7_-_29125142 0.345 ENSMUST00000179893.1
ENSMUST00000032813.9
Ryr1

ryanodine receptor 1, skeletal muscle

chr7_+_19291070 0.344 ENSMUST00000108468.3
Rtn2
reticulon 2 (Z-band associated protein)
chr4_-_132533488 0.341 ENSMUST00000152993.1
ENSMUST00000067496.6
Atpif1

ATPase inhibitory factor 1

chr2_+_179893909 0.341 ENSMUST00000098996.1
Gm10711
predicted gene 10711
chr4_-_118490030 0.339 ENSMUST00000047421.5
Tie1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr11_+_83409655 0.339 ENSMUST00000175848.1
ENSMUST00000108140.3
Rasl10b

RAS-like, family 10, member B

chr2_-_24763047 0.338 ENSMUST00000100348.3
ENSMUST00000041342.5
ENSMUST00000114447.1
ENSMUST00000102939.2
ENSMUST00000070864.7
Cacna1b




calcium channel, voltage-dependent, N type, alpha 1B subunit




chr11_+_101155884 0.338 ENSMUST00000043654.9
Tubg2
tubulin, gamma 2
chr7_+_27233003 0.338 ENSMUST00000003860.6
ENSMUST00000108378.3
Adck4

aarF domain containing kinase 4

chr11_+_83409137 0.337 ENSMUST00000021022.3
Rasl10b
RAS-like, family 10, member B
chr1_+_91179822 0.334 ENSMUST00000097648.4
ENSMUST00000165855.1
Ramp1

receptor (calcitonin) activity modifying protein 1

chr7_+_24507006 0.334 ENSMUST00000176880.1
Zfp428
zinc finger protein 428
chr16_+_17561885 0.333 ENSMUST00000171002.1
ENSMUST00000023441.4
P2rx6

purinergic receptor P2X, ligand-gated ion channel, 6

chr7_+_46396439 0.331 ENSMUST00000025202.6
Kcnc1
potassium voltage gated channel, Shaw-related subfamily, member 1
chrX_+_94234921 0.331 ENSMUST00000113908.1
ENSMUST00000113916.3
Klhl15

kelch-like 15

chr8_+_70315759 0.329 ENSMUST00000165819.2
ENSMUST00000140239.1
Gdf1
Cers1
growth differentiation factor 1
ceramide synthase 1
chr11_-_116110211 0.329 ENSMUST00000106441.1
ENSMUST00000021120.5
Trim47

tripartite motif-containing 47

chr1_-_173367638 0.328 ENSMUST00000005470.4
ENSMUST00000111220.1
Cadm3

cell adhesion molecule 3

chr1_+_90998722 0.327 ENSMUST00000068116.6
Lrrfip1
leucine rich repeat (in FLII) interacting protein 1
chr6_+_90619241 0.326 ENSMUST00000032177.8
Slc41a3
solute carrier family 41, member 3
chr9_-_44288131 0.325 ENSMUST00000160384.1
Abcg4
ATP-binding cassette, sub-family G (WHITE), member 4
chr11_+_84179852 0.322 ENSMUST00000136463.2
Acaca
acetyl-Coenzyme A carboxylase alpha
chr8_-_106337987 0.321 ENSMUST00000067512.7
Smpd3
sphingomyelin phosphodiesterase 3, neutral
chr17_-_24209377 0.320 ENSMUST00000024931.4
Ntn3
netrin 3
chr17_-_45686120 0.320 ENSMUST00000143907.1
ENSMUST00000127065.1
Tmem63b

transmembrane protein 63b

chr12_-_27160311 0.319 ENSMUST00000182473.1
ENSMUST00000177636.1
ENSMUST00000183238.1
Gm9866


predicted gene 9866


chrX_-_136958000 0.318 ENSMUST00000069803.4
Tmsb15b2
thymosin beta 15b2
chr11_+_70018728 0.317 ENSMUST00000018700.6
ENSMUST00000134376.2
Dlg4

discs, large homolog 4 (Drosophila)

chr15_-_37791993 0.316 ENSMUST00000168992.1
ENSMUST00000148652.1
Ncald

neurocalcin delta

chr18_+_24709436 0.313 ENSMUST00000037097.7
Fhod3
formin homology 2 domain containing 3
chr14_+_57524734 0.307 ENSMUST00000089494.4
Il17d
interleukin 17D
chr6_+_117168535 0.305 ENSMUST00000112866.1
ENSMUST00000112871.1
ENSMUST00000073043.4
Cxcl12


chemokine (C-X-C motif) ligand 12


chr7_-_74554474 0.305 ENSMUST00000134539.1
ENSMUST00000026897.7
ENSMUST00000098371.2
Slco3a1


solute carrier organic anion transporter family, member 3a1


chr15_-_81960851 0.305 ENSMUST00000071462.6
ENSMUST00000023112.5
Pmm1

phosphomannomutase 1

chr8_-_70776650 0.304 ENSMUST00000034296.8
Pik3r2
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta)
chr2_-_32353283 0.303 ENSMUST00000091089.5
ENSMUST00000113350.1
Dnm1

dynamin 1

chr17_-_57059795 0.302 ENSMUST00000040280.7
Slc25a23
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
chr2_+_82053222 0.299 ENSMUST00000047527.7
Zfp804a
zinc finger protein 804A
chr11_-_72135721 0.297 ENSMUST00000108508.2
ENSMUST00000075258.6
Pitpnm3

PITPNM family member 3

chr6_+_129533183 0.297 ENSMUST00000032264.6
Gabarapl1
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
chr7_-_29156160 0.297 ENSMUST00000144795.1
ENSMUST00000134176.1
ENSMUST00000164589.1
ENSMUST00000136256.1
Fam98c



family with sequence similarity 98, member C



chr7_-_74554726 0.296 ENSMUST00000107453.1
Slco3a1
solute carrier organic anion transporter family, member 3a1
chr15_-_85503227 0.296 ENSMUST00000178942.1
7530416G11Rik
RIKEN cDNA 7530416G11 gene
chr1_+_132191436 0.296 ENSMUST00000112357.2
Lemd1
LEM domain containing 1
chr12_-_12940600 0.295 ENSMUST00000130990.1
Mycn
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr8_-_105289465 0.293 ENSMUST00000171788.1
ENSMUST00000014981.6
4931428F04Rik

RIKEN cDNA 4931428F04 gene


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.4 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
1.1 3.2 GO:0099548 drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738) retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by nitric oxide(GO:0099548)
0.4 2.0 GO:0071692 protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
0.4 1.1 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
0.3 2.0 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.3 1.2 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.3 1.5 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.3 2.0 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.3 1.5 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.2 1.0 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.2 1.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.2 1.5 GO:0032811 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) negative regulation of epinephrine secretion(GO:0032811)
0.2 0.6 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.2 3.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.2 0.6 GO:1905072 detection of oxygen(GO:0003032) cardiac jelly development(GO:1905072)
0.2 0.5 GO:0071492 cellular response to UV-A(GO:0071492)
0.2 0.5 GO:0061144 alveolar secondary septum development(GO:0061144)
0.2 0.8 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.1 0.1 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.1 1.0 GO:0051775 response to redox state(GO:0051775)
0.1 0.1 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.1 0.4 GO:0071317 cellular response to isoquinoline alkaloid(GO:0071317)
0.1 1.4 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 0.4 GO:0016115 terpenoid catabolic process(GO:0016115)
0.1 0.7 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.5 GO:0044268 multicellular organismal protein metabolic process(GO:0044268)
0.1 1.3 GO:0060347 heart trabecula formation(GO:0060347)
0.1 0.5 GO:0051582 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.1 0.6 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 0.1 GO:1902534 single-organism membrane invagination(GO:1902534)
0.1 0.6 GO:1902287 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.1 0.9 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 0.3 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 0.3 GO:0097274 urea homeostasis(GO:0097274)
0.1 0.4 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.1 0.1 GO:0060003 copper ion export(GO:0060003)
0.1 0.5 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.1 0.1 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.1 0.2 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 0.5 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 0.7 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.1 0.4 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.1 0.9 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 1.9 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.1 0.5 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.5 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 0.5 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1 0.4 GO:1904995 negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.1 0.3 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.1 0.3 GO:0071313 cellular response to caffeine(GO:0071313)
0.1 0.2 GO:1904058 positive regulation of sensory perception of pain(GO:1904058)
0.1 0.3 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.1 0.4 GO:1905169 protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171)
0.1 0.6 GO:0005513 detection of calcium ion(GO:0005513)
0.1 1.0 GO:2000821 regulation of grooming behavior(GO:2000821)
0.1 0.4 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
0.1 4.7 GO:0021696 cerebellar cortex morphogenesis(GO:0021696)
0.1 0.5 GO:0072318 clathrin coat disassembly(GO:0072318)
0.1 0.3 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 0.2 GO:0007521 muscle cell fate determination(GO:0007521)
0.1 0.2 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.1 0.4 GO:1990034 calcium ion export from cell(GO:1990034)
0.1 0.4 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 1.0 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 0.1 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.1 0.1 GO:2000277 positive regulation of oxidative phosphorylation uncoupler activity(GO:2000277)
0.1 0.2 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.1 0.2 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.2 GO:0071677 positive regulation of mononuclear cell migration(GO:0071677)
0.1 0.3 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.1 0.2 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.1 0.5 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 0.4 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.1 0.1 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.1 0.2 GO:1904580 regulation of polynucleotide adenylyltransferase activity(GO:1904245) regulation of intracellular mRNA localization(GO:1904580)
0.1 0.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 1.3 GO:0033198 response to ATP(GO:0033198)
0.1 0.7 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.1 0.3 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.1 0.2 GO:0070671 response to interleukin-12(GO:0070671)
0.1 0.4 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 0.3 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 0.2 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.1 0.2 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 0.2 GO:1903860 negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800)
0.1 0.2 GO:0043181 vacuolar sequestering(GO:0043181)
0.1 0.3 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.1 0.5 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.5 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.1 0.2 GO:0060084 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) synaptic transmission involved in micturition(GO:0060084)
0.1 0.2 GO:1902220 positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902220)
0.0 0.2 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.1 GO:0048611 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.0 0.2 GO:0060178 regulation of exocyst localization(GO:0060178)
0.0 0.4 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.3 GO:0031000 response to caffeine(GO:0031000)
0.0 0.2 GO:0021592 fourth ventricle development(GO:0021592) initiation of neural tube closure(GO:0021993)
0.0 0.4 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.2 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.1 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.4 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.2 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.2 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.5 GO:1900746 regulation of vascular endothelial growth factor signaling pathway(GO:1900746)
0.0 0.2 GO:0032423 regulation of mismatch repair(GO:0032423)
0.0 0.2 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.1 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.2 GO:0021886 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.0 0.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.2 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.0 0.2 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.2 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.0 0.2 GO:0019236 response to pheromone(GO:0019236)
0.0 0.3 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.6 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.1 GO:0043379 rRNA export from nucleus(GO:0006407) memory T cell differentiation(GO:0043379) response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.1 GO:0043388 positive regulation of DNA binding(GO:0043388)
0.0 0.2 GO:0010796 regulation of multivesicular body size(GO:0010796)
0.0 0.5 GO:0035646 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.0 0.2 GO:0000189 MAPK import into nucleus(GO:0000189) regulation of Golgi inheritance(GO:0090170)
0.0 0.3 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.2 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 0.3 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.4 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.2 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.1 GO:0070269 pyroptosis(GO:0070269)
0.0 0.2 GO:0044539 long-chain fatty acid import(GO:0044539)
0.0 0.1 GO:0045575 basophil activation involved in immune response(GO:0002276) basophil activation(GO:0045575)
0.0 0.1 GO:0009405 pathogenesis(GO:0009405)
0.0 0.2 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.3 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.1 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:0046898 response to cycloheximide(GO:0046898)
0.0 0.3 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0 0.4 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 1.9 GO:0008542 visual learning(GO:0008542)
0.0 0.1 GO:0021604 cranial nerve structural organization(GO:0021604)
0.0 0.3 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.2 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.2 GO:1903358 regulation of Golgi organization(GO:1903358)
0.0 0.5 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.2 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.1 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.0 1.0 GO:0033344 cholesterol efflux(GO:0033344)
0.0 0.1 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.1 GO:2001197 basement membrane assembly(GO:0070831) regulation of extracellular matrix assembly(GO:1901201) positive regulation of extracellular matrix assembly(GO:1901203) positive regulation of extracellular matrix organization(GO:1903055) regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.1 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.5 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0032570 response to progesterone(GO:0032570)
0.0 0.3 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.0 0.3 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577)
0.0 0.8 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 0.1 GO:0032364 oxygen homeostasis(GO:0032364)
0.0 0.4 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.7 GO:0043496 regulation of protein homodimerization activity(GO:0043496)
0.0 0.2 GO:0046929 negative regulation of neurotransmitter secretion(GO:0046929)
0.0 0.1 GO:0034384 high-density lipoprotein particle remodeling(GO:0034375) high-density lipoprotein particle clearance(GO:0034384) reverse cholesterol transport(GO:0043691)
0.0 0.3 GO:0001956 positive regulation of neurotransmitter secretion(GO:0001956)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.4 GO:0044804 nucleophagy(GO:0044804)
0.0 0.6 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.1 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.0 0.2 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.0 1.0 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.1 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.0 0.5 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.2 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.1 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.1 GO:0036481 intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036481)
0.0 0.0 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:0010958 regulation of amino acid import(GO:0010958)
0.0 0.1 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.0 0.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 1.3 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.2 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.3 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.6 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.3 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.0 GO:0033092 positive regulation of immature T cell proliferation(GO:0033091) positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.0 0.1 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.0 0.1 GO:2000189 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.2 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 0.2 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.0 0.3 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.1 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.0 0.1 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.0 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667) regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.0 0.2 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.1 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.0 0.1 GO:0071474 cellular hyperosmotic response(GO:0071474)
0.0 0.2 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.2 GO:0031424 keratinization(GO:0031424)
0.0 0.5 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.1 GO:2001184 regulation of interleukin-12 secretion(GO:2001182) positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.2 GO:0009072 aromatic amino acid family metabolic process(GO:0009072)
0.0 0.1 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.0 0.2 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 1.7 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.2 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.0 0.2 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.0 GO:0035973 aggrephagy(GO:0035973)
0.0 0.1 GO:0061368 maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368) modification of postsynaptic actin cytoskeleton(GO:0098885)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0032264 IMP salvage(GO:0032264)
0.0 0.2 GO:0043084 penile erection(GO:0043084)
0.0 0.2 GO:0032402 melanosome transport(GO:0032402)
0.0 0.0 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.0 GO:1904008 response to monosodium glutamate(GO:1904008) cellular response to monosodium glutamate(GO:1904009)
0.0 0.3 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.0 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.0 0.1 GO:0044144 regulation of growth of symbiont in host(GO:0044126) modulation of growth of symbiont involved in interaction with host(GO:0044144)
0.0 0.2 GO:0032060 bleb assembly(GO:0032060)
0.0 0.0 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.0 0.0 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.2 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.0 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.0 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.1 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0090292 nuclear matrix organization(GO:0043578) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) nuclear matrix anchoring at nuclear membrane(GO:0090292) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.0 GO:0045113 regulation of integrin biosynthetic process(GO:0045113)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.0 GO:1902608 regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.0 0.4 GO:0042993 positive regulation of transcription factor import into nucleus(GO:0042993)
0.0 0.1 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.0 0.1 GO:0031648 protein destabilization(GO:0031648)
0.0 0.2 GO:0022028 tangential migration from the subventricular zone to the olfactory bulb(GO:0022028)
0.0 0.2 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.0 0.1 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
0.0 0.5 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.5 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.1 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.3 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.0 0.2 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.3 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.3 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.1 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.0 0.3 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.1 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.3 GO:0046326 positive regulation of glucose import(GO:0046326)
0.0 0.1 GO:0009437 carnitine metabolic process(GO:0009437)
0.0 0.6 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.3 GO:0046324 regulation of glucose import(GO:0046324)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.4 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.4 2.4 GO:0008091 spectrin(GO:0008091)
0.4 4.8 GO:0044327 dendritic spine head(GO:0044327)
0.4 1.1 GO:0098835 presynaptic endosome(GO:0098830) presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.3 1.5 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.3 0.8 GO:0072534 perineuronal net(GO:0072534)
0.3 2.8 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.2 0.7 GO:0014802 terminal cisterna(GO:0014802)
0.2 2.0 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.4 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 0.8 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.4 GO:0098842 postsynaptic early endosome(GO:0098842)
0.1 0.4 GO:1990769 proximal neuron projection(GO:1990769)
0.1 0.1 GO:1902737 dendritic filopodium(GO:1902737)
0.1 0.8 GO:0042581 specific granule(GO:0042581)
0.1 0.1 GO:0030128 clathrin coat of endocytic vesicle(GO:0030128) clathrin-coated endocytic vesicle membrane(GO:0030669)
0.1 1.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.1 GO:0044294 dendritic growth cone(GO:0044294)
0.1 1.5 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 0.1 GO:0044194 cytolytic granule(GO:0044194)
0.1 0.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.3 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1 0.3 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.3 GO:0097447 dendritic tree(GO:0097447)
0.1 1.0 GO:0043196 varicosity(GO:0043196)
0.1 0.8 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.5 GO:0005915 zonula adherens(GO:0005915)
0.0 0.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.5 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.2 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 1.8 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.1 GO:0051286 cell tip(GO:0051286)
0.0 0.2 GO:0097443 sorting endosome(GO:0097443)
0.0 0.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.2 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0061702 inflammasome complex(GO:0061702)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.6 GO:0000124 SAGA complex(GO:0000124)
0.0 3.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 1.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 1.0 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.4 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.1 GO:0045178 basal part of cell(GO:0045178)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)
0.0 0.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.6 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.4 GO:0031045 dense core granule(GO:0031045)
0.0 0.8 GO:0097440 apical dendrite(GO:0097440)
0.0 0.1 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.3 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 2.2 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.5 GO:0031430 M band(GO:0031430)
0.0 0.1 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 1.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 1.1 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.2 GO:0031143 pseudopodium(GO:0031143)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0016600 flotillin complex(GO:0016600)
0.0 0.9 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.5 GO:0005776 autophagosome(GO:0005776)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.4 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.1 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.9 GO:0031941 filamentous actin(GO:0031941)
0.0 0.0 GO:0098576 lumenal side of membrane(GO:0098576)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 0.0 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.2 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.2 GO:0036038 MKS complex(GO:0036038)
0.0 0.7 GO:0014704 intercalated disc(GO:0014704)
0.0 0.1 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.4 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.6 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.2 GO:0005901 caveola(GO:0005901)
0.0 0.0 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.3 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0 0.5 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0097542 ciliary tip(GO:0097542)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 3.4 GO:0097060 synaptic membrane(GO:0097060)
0.0 0.1 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.4 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.5 GO:0016528 sarcoplasm(GO:0016528)
0.0 0.2 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.4 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.4 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.1 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 0.2 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.6 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.3 0.9 GO:0004994 somatostatin receptor activity(GO:0004994)
0.3 1.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.3 1.0 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.3 1.5 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.2 0.7 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.2 0.5 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.2 1.1 GO:0019841 retinol binding(GO:0019841)
0.2 0.9 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.2 0.9 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.2 1.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.2 0.5 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 0.6 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 1.4 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.1 0.5 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.4 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.1 0.6 GO:0005534 galactose binding(GO:0005534)
0.1 0.6 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.5 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.3 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.1 0.6 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 1.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.8 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 0.6 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.1 0.2 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 0.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.9 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.3 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.2 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.1 1.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.9 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.1 0.2 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.1 1.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.3 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.1 0.3 GO:0043532 angiostatin binding(GO:0043532)
0.1 0.3 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.1 0.3 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 0.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.3 GO:0097643 amylin receptor activity(GO:0097643)
0.1 0.9 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 0.3 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.1 0.3 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.1 0.4 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 1.3 GO:0030506 ankyrin binding(GO:0030506)
0.1 0.5 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.5 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.5 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.1 0.1 GO:0033142 progesterone receptor binding(GO:0033142)
0.1 0.3 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 0.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.3 GO:0070330 aromatase activity(GO:0070330)
0.1 0.2 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 0.2 GO:0070976 calcium-independent protein kinase C activity(GO:0004699) TIR domain binding(GO:0070976)
0.1 0.4 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 0.6 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.9 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.7 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.4 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.1 GO:1990955 G-rich single-stranded DNA binding(GO:1990955)
0.0 0.1 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.0 0.1 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.4 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.2 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.2 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0019002 GMP binding(GO:0019002)
0.0 0.4 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.3 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.1 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.0 0.1 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.0 0.2 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0043682 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.0 0.2 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 1.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.5 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.1 GO:0004075 biotin carboxylase activity(GO:0004075)
0.0 0.1 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.4 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.5 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.4 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.1 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.3 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.1 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.1 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.1 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.0 0.1 GO:0016880 acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.2 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.5 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.6 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.1 GO:1901612 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.0 0.3 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.0 GO:0036361 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.2 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.4 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.2 GO:0019956 chemokine binding(GO:0019956)
0.0 0.3 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.4 GO:0030276 clathrin binding(GO:0030276)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 1.8 GO:0000149 SNARE binding(GO:0000149)
0.0 0.5 GO:0030546 receptor activator activity(GO:0030546)
0.0 0.1 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.2 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.5 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.0 0.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.0 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.0 0.1 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.2 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:1990188 euchromatin binding(GO:1990188)
0.0 0.1 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.1 GO:0030957 Tat protein binding(GO:0030957)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.5 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.0 0.2 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.0 1.4 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.5 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.9 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.0 1.0 SA_TRKA_RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.6 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.0 1.0 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.3 PID_FAS_PATHWAY FAS (CD95) signaling pathway
0.0 0.7 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 1.0 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.2 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 2.6 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.1 PID_AR_NONGENOMIC_PATHWAY Nongenotropic Androgen signaling
0.0 0.5 PID_ALK1_PATHWAY ALK1 signaling events
0.0 0.3 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 0.1 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.0 0.3 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.0 0.2 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.0 0.5 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.4 SIG_BCR_SIGNALING_PATHWAY Members of the BCR signaling pathway
0.0 0.8 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 1.1 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.0 0.1 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.5 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 0.3 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 0.1 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.2 PID_PI3KCI_PATHWAY Class I PI3K signaling events
0.0 0.6 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.2 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.1 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.1 PID_CD40_PATHWAY CD40/CD40L signaling
0.0 0.2 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.4 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.3 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.5 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 3.3 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 3.5 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 0.8 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.1 2.3 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 1.0 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.1 0.7 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.1 0.6 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 1.0 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.6 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.8 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.3 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.0 0.4 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.5 REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.5 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.4 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 3.0 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.4 REACTOME_INWARDLY_RECTIFYING_K_CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.2 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.5 REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.3 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.5 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.5 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.4 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.4 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.3 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.4 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.3 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.5 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.8 REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.4 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.6 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 0.5 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.1 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.2 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.3 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.3 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.5 REACTOME_PIP3_ACTIVATES_AKT_SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.5 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.6 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.3 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.9 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.0 0.3 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 1.1 REACTOME_INTEGRATION_OF_ENERGY_METABOLISM Genes involved in Integration of energy metabolism
0.0 0.3 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.0 0.3 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.1 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.2 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.0 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.2 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.9 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.1 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.6 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.4 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.1 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.1 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes