Motif ID: Smad4

Z-value: 1.333


Transcription factors associated with Smad4:

Gene SymbolEntrez IDGene Name
Smad4 ENSMUSG00000024515.7 Smad4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Smad4mm10_v2_chr18_-_73703739_73703806-0.314.9e-02Click!


Activity profile for motif Smad4.

activity profile for motif Smad4


Sorted Z-values histogram for motif Smad4

Sorted Z-values for motif Smad4



Network of associatons between targets according to the STRING database.



First level regulatory network of Smad4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_103314944 16.513 ENSMUST00000179363.1
Fam181a
family with sequence similarity 181, member A
chr2_+_70562854 11.645 ENSMUST00000130998.1
Gad1
glutamate decarboxylase 1
chr2_+_70563435 11.017 ENSMUST00000123330.1
Gad1
glutamate decarboxylase 1
chr10_-_42583628 10.955 ENSMUST00000019938.4
Nr2e1
nuclear receptor subfamily 2, group E, member 1
chr14_-_54577578 9.801 ENSMUST00000054487.8
Ajuba
ajuba LIM protein
chr11_-_89302545 9.174 ENSMUST00000061728.3
Nog
noggin
chr18_+_57133065 8.832 ENSMUST00000075770.6
Megf10
multiple EGF-like-domains 10
chr19_-_40271506 6.395 ENSMUST00000068439.6
Pdlim1
PDZ and LIM domain 1 (elfin)
chr14_+_50944499 6.298 ENSMUST00000178092.1
Pnp
purine-nucleoside phosphorylase
chr17_-_70851710 5.951 ENSMUST00000166395.2
Tgif1
TGFB-induced factor homeobox 1
chr7_+_45216671 5.511 ENSMUST00000134420.1
Tead2
TEA domain family member 2
chr15_-_103366763 5.510 ENSMUST00000023128.6
Itga5
integrin alpha 5 (fibronectin receptor alpha)
chr7_-_89517576 5.510 ENSMUST00000041761.5
Prss23
protease, serine, 23
chr4_-_117178726 5.050 ENSMUST00000153953.1
ENSMUST00000106436.1
Kif2c

kinesin family member 2C

chr4_-_95052170 5.044 ENSMUST00000058555.2
Jun
Jun oncogene
chr13_-_21832194 4.997 ENSMUST00000102979.1
Hist1h4n
histone cluster 1, H4n
chr6_+_108660772 4.892 ENSMUST00000163617.1
Bhlhe40
basic helix-loop-helix family, member e40
chr13_-_102958084 4.644 ENSMUST00000099202.3
ENSMUST00000172264.1
Mast4

microtubule associated serine/threonine kinase family member 4

chr6_+_15720654 4.489 ENSMUST00000101663.3
Mdfic
MyoD family inhibitor domain containing
chr7_+_117380937 4.483 ENSMUST00000032892.5
Xylt1
xylosyltransferase 1
chr7_+_110221697 4.142 ENSMUST00000033325.7
Swap70
SWA-70 protein
chr7_+_45215753 3.921 ENSMUST00000033060.6
ENSMUST00000155313.1
ENSMUST00000107801.1
Tead2


TEA domain family member 2


chr3_+_89436699 3.906 ENSMUST00000038942.3
ENSMUST00000130858.1
Pbxip1

pre B cell leukemia transcription factor interacting protein 1

chr13_-_23551648 3.756 ENSMUST00000102971.1
Hist1h4f
histone cluster 1, H4f
chr1_+_187997821 3.740 ENSMUST00000027906.6
Esrrg
estrogen-related receptor gamma
chr2_+_152736244 3.718 ENSMUST00000038368.8
ENSMUST00000109824.1
Id1

inhibitor of DNA binding 1

chr1_+_187997835 3.701 ENSMUST00000110938.1
Esrrg
estrogen-related receptor gamma
chr13_+_23581563 3.620 ENSMUST00000102968.1
Hist1h4d
histone cluster 1, H4d
chrX_+_56779437 3.457 ENSMUST00000114773.3
Fhl1
four and a half LIM domains 1
chr9_-_21852603 3.348 ENSMUST00000034728.7
Dock6
dedicator of cytokinesis 6
chr15_-_98728120 3.308 ENSMUST00000003445.6
Fkbp11
FK506 binding protein 11
chr13_+_23531044 3.250 ENSMUST00000102972.3
Hist1h4h
histone cluster 1, H4h
chr14_-_57826128 3.193 ENSMUST00000022536.2
Ska3
spindle and kinetochore associated complex subunit 3
chrX_-_72274747 3.174 ENSMUST00000064780.3
Gabre
gamma-aminobutyric acid (GABA) A receptor, subunit epsilon
chr14_-_25903100 3.119 ENSMUST00000052286.8
Plac9a
placenta specific 9a
chr13_-_22042949 3.039 ENSMUST00000091741.4
Hist1h2ag
histone cluster 1, H2ag
chr5_+_92683625 3.021 ENSMUST00000168878.1
Shroom3
shroom family member 3
chr4_+_117835387 2.925 ENSMUST00000169885.1
Slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr11_-_33147400 2.885 ENSMUST00000020507.7
Fgf18
fibroblast growth factor 18
chr14_-_54554359 2.880 ENSMUST00000022784.8
Haus4
HAUS augmin-like complex, subunit 4
chr7_+_101394361 2.837 ENSMUST00000154239.1
ENSMUST00000098243.2
Arap1

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

chr3_+_89436736 2.809 ENSMUST00000146630.1
ENSMUST00000145753.1
Pbxip1

pre B cell leukemia transcription factor interacting protein 1

chr13_+_22043189 2.771 ENSMUST00000110452.1
Hist1h2bj
histone cluster 1, H2bj
chr17_+_75178797 2.764 ENSMUST00000112516.1
ENSMUST00000135447.1
Ltbp1

latent transforming growth factor beta binding protein 1

chr2_+_27676440 2.710 ENSMUST00000129514.1
Rxra
retinoid X receptor alpha
chr11_-_106160101 2.651 ENSMUST00000045923.3
Limd2
LIM domain containing 2
chr19_-_31664356 2.628 ENSMUST00000073581.5
Prkg1
protein kinase, cGMP-dependent, type I
chr17_+_75178911 2.583 ENSMUST00000112514.1
Ltbp1
latent transforming growth factor beta binding protein 1
chr10_-_92164666 2.582 ENSMUST00000183123.1
ENSMUST00000182033.1
Rmst

rhabdomyosarcoma 2 associated transcript (non-coding RNA)

chr7_-_70360593 2.568 ENSMUST00000032768.7
Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr11_-_26591729 2.539 ENSMUST00000109504.1
Vrk2
vaccinia related kinase 2
chr1_+_153652943 2.415 ENSMUST00000041776.5
Rgs8
regulator of G-protein signaling 8
chr6_-_138422898 2.386 ENSMUST00000161450.1
ENSMUST00000163024.1
ENSMUST00000162185.1
Lmo3


LIM domain only 3


chr5_+_7179299 2.359 ENSMUST00000179460.1
Tubb4b-ps1
tubulin, beta 4B class IVB, pseudogene 1
chr10_+_80150448 2.276 ENSMUST00000153477.1
Midn
midnolin
chr13_+_21735055 2.163 ENSMUST00000087714.4
Hist1h4j
histone cluster 1, H4j
chr17_+_34597852 2.109 ENSMUST00000174496.2
ENSMUST00000015596.3
ENSMUST00000173992.1
Ager


advanced glycosylation end product-specific receptor


chr15_-_38300693 2.050 ENSMUST00000074043.5
Klf10
Kruppel-like factor 10
chr11_-_106159902 1.915 ENSMUST00000064545.4
Limd2
LIM domain containing 2
chr6_+_147032528 1.902 ENSMUST00000036194.4
Rep15
RAB15 effector protein
chr9_+_106429537 1.885 ENSMUST00000059802.6
Rpl29
ribosomal protein L29
chr17_+_46646225 1.879 ENSMUST00000002844.7
ENSMUST00000113429.1
ENSMUST00000113430.1
Mrpl2


mitochondrial ribosomal protein L2


chr9_+_96895617 1.852 ENSMUST00000071781.6
Gm10123
predicted pseudogene 10123
chr10_+_91082940 1.806 ENSMUST00000020150.3
Ikbip
IKBKB interacting protein
chrX_+_99136119 1.768 ENSMUST00000052839.6
Efnb1
ephrin B1
chr3_-_146839365 1.754 ENSMUST00000084614.3
Gm10288
predicted gene 10288
chr10_+_75589363 1.724 ENSMUST00000072217.2
Ggt5
gamma-glutamyltransferase 5
chr11_+_60699758 1.649 ENSMUST00000108719.3
Llgl1
lethal giant larvae homolog 1 (Drosophila)
chr6_+_54040078 1.639 ENSMUST00000127323.2
Chn2
chimerin (chimaerin) 2
chr8_-_92356103 1.635 ENSMUST00000034183.3
4933436C20Rik
RIKEN cDNA 4933436C20 gene
chrX_+_136270302 1.542 ENSMUST00000113112.1
Ngfrap1
nerve growth factor receptor (TNFRSF16) associated protein 1
chrX_+_136270253 1.531 ENSMUST00000178632.1
ENSMUST00000053540.4
Ngfrap1

nerve growth factor receptor (TNFRSF16) associated protein 1

chr14_-_104467984 1.512 ENSMUST00000053016.8
Pou4f1
POU domain, class 4, transcription factor 1
chr5_+_30913398 1.508 ENSMUST00000031055.5
Emilin1
elastin microfibril interfacer 1
chr7_-_45052865 1.495 ENSMUST00000057293.6
Prr12
proline rich 12
chr14_+_64950037 1.481 ENSMUST00000043914.5
Ints9
integrator complex subunit 9
chr11_+_60699718 1.475 ENSMUST00000052346.3
Llgl1
lethal giant larvae homolog 1 (Drosophila)
chr6_+_54039935 1.435 ENSMUST00000114403.1
Chn2
chimerin (chimaerin) 2
chr11_-_5261558 1.434 ENSMUST00000020662.8
Kremen1
kringle containing transmembrane protein 1
chr7_+_141216626 1.423 ENSMUST00000141804.1
ENSMUST00000148975.1
Rassf7

Ras association (RalGDS/AF-6) domain family (N-terminal) member 7

chr11_-_106160708 1.420 ENSMUST00000106875.1
Limd2
LIM domain containing 2
chr11_-_60115226 1.417 ENSMUST00000130746.1
4930412M03Rik
RIKEN cDNA 4930412M03 gene
chr6_+_54039558 1.402 ENSMUST00000046856.7
Chn2
chimerin (chimaerin) 2
chr4_+_130055010 1.394 ENSMUST00000123617.1
Col16a1
collagen, type XVI, alpha 1
chr2_+_120476911 1.389 ENSMUST00000110716.1
ENSMUST00000028748.6
ENSMUST00000090028.5
ENSMUST00000110719.2
Capn3



calpain 3



chr4_-_134245579 1.384 ENSMUST00000030644.7
Zfp593
zinc finger protein 593
chr9_-_20898592 1.383 ENSMUST00000004206.8
Eif3g
eukaryotic translation initiation factor 3, subunit G
chr14_+_12189943 1.378 ENSMUST00000119888.1
Ptprg
protein tyrosine phosphatase, receptor type, G
chr3_+_36552600 1.333 ENSMUST00000029269.5
ENSMUST00000136890.1
Exosc9

exosome component 9

chr3_+_127633134 1.329 ENSMUST00000029587.7
Neurog2
neurogenin 2
chr11_-_3931789 1.320 ENSMUST00000109992.1
ENSMUST00000109988.1
Tcn2

transcobalamin 2

chr11_-_115419917 1.316 ENSMUST00000106537.1
ENSMUST00000043931.2
ENSMUST00000073791.3
Atp5h


ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d


chr10_+_127739516 1.223 ENSMUST00000054287.7
Zbtb39
zinc finger and BTB domain containing 39
chr15_+_102977032 1.211 ENSMUST00000001706.6
Hoxc9
homeobox C9
chr13_-_115090123 1.176 ENSMUST00000109226.3
Pelo
pelota homolog (Drosophila)
chr4_+_128688726 1.156 ENSMUST00000106080.1
Phc2
polyhomeotic-like 2 (Drosophila)
chr11_-_3931960 1.124 ENSMUST00000109990.1
ENSMUST00000020710.4
ENSMUST00000109989.3
ENSMUST00000109991.1
ENSMUST00000109993.2
Tcn2




transcobalamin 2




chr17_-_46031813 1.107 ENSMUST00000024747.7
Vegfa
vascular endothelial growth factor A
chr17_+_34263209 1.070 ENSMUST00000040828.5
H2-Ab1
histocompatibility 2, class II antigen A, beta 1
chr9_+_44072196 1.043 ENSMUST00000176671.1
Usp2
ubiquitin specific peptidase 2
chr3_+_68572245 1.026 ENSMUST00000170788.2
Schip1
schwannomin interacting protein 1
chr5_+_32611171 1.003 ENSMUST00000072311.6
ENSMUST00000168707.2
Yes1

Yamaguchi sarcoma viral (v-yes) oncogene homolog 1

chr2_+_27079371 0.977 ENSMUST00000091233.6
Adamtsl2
ADAMTS-like 2
chr19_-_5295397 0.968 ENSMUST00000025774.9
Sf3b2
splicing factor 3b, subunit 2
chr1_-_143702832 0.955 ENSMUST00000018337.7
Cdc73
cell division cycle 73, Paf1/RNA polymerase II complex component
chr9_+_61373219 0.948 ENSMUST00000162583.1
ENSMUST00000161993.1
ENSMUST00000160882.1
ENSMUST00000160724.1
ENSMUST00000162973.1
ENSMUST00000159050.1
Tle3





transducin-like enhancer of split 3, homolog of Drosophila E(spl)





chr8_+_95825353 0.937 ENSMUST00000074053.4
Gm10094
predicted gene 10094
chr4_+_118621160 0.921 ENSMUST00000147373.1
Ebna1bp2
EBNA1 binding protein 2
chr3_+_96221111 0.915 ENSMUST00000090781.6
Hist2h2be
histone cluster 2, H2be
chr5_+_120431770 0.902 ENSMUST00000031591.7
Lhx5
LIM homeobox protein 5
chr5_-_24445166 0.891 ENSMUST00000115043.1
ENSMUST00000115041.1
Fastk

Fas-activated serine/threonine kinase

chr3_+_63295815 0.879 ENSMUST00000029400.1
Mme
membrane metallo endopeptidase
chr14_-_20496780 0.849 ENSMUST00000022353.3
Mss51
MSS51 mitochondrial translational activator
chr9_+_61373482 0.832 ENSMUST00000160541.1
ENSMUST00000161207.1
ENSMUST00000159630.1
Tle3


transducin-like enhancer of split 3, homolog of Drosophila E(spl)


chr11_+_97663366 0.805 ENSMUST00000044730.5
Mllt6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr11_+_4637734 0.795 ENSMUST00000109930.2
ENSMUST00000070257.7
Ascc2

activating signal cointegrator 1 complex subunit 2

chr1_-_45503282 0.768 ENSMUST00000086430.4
Col5a2
collagen, type V, alpha 2
chr9_+_61373608 0.765 ENSMUST00000161689.1
Tle3
transducin-like enhancer of split 3, homolog of Drosophila E(spl)
chr11_-_48816936 0.761 ENSMUST00000140800.1
Trim41
tripartite motif-containing 41
chr3_+_102734496 0.714 ENSMUST00000029451.5
Tspan2
tetraspanin 2
chr17_-_35162969 0.707 ENSMUST00000174805.1
Prrc2a
proline-rich coiled-coil 2A
chr11_+_115420059 0.673 ENSMUST00000103035.3
Kctd2
potassium channel tetramerisation domain containing 2
chr5_-_24445254 0.645 ENSMUST00000030800.6
Fastk
Fas-activated serine/threonine kinase
chr14_-_31168587 0.609 ENSMUST00000036618.7
Stab1
stabilin 1
chr18_-_35498856 0.587 ENSMUST00000025215.8
Sil1
endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae)
chr10_+_33905015 0.576 ENSMUST00000169670.1
Rsph4a
radial spoke head 4 homolog A (Chlamydomonas)
chr12_-_109600328 0.575 ENSMUST00000149046.2
Rtl1
retrotransposon-like 1
chr14_+_57826210 0.575 ENSMUST00000022538.3
Mrp63
mitochondrial ribosomal protein 63
chr15_+_102102926 0.557 ENSMUST00000169627.1
ENSMUST00000046144.9
Tenc1

tensin like C1 domain-containing phosphatase

chr12_+_76404168 0.545 ENSMUST00000080449.5
Hspa2
heat shock protein 2
chr4_+_126677630 0.537 ENSMUST00000030642.2
Psmb2
proteasome (prosome, macropain) subunit, beta type 2
chr3_-_96220880 0.533 ENSMUST00000090782.3
Hist2h2ac
histone cluster 2, H2ac
chr11_-_102319093 0.530 ENSMUST00000174302.1
ENSMUST00000178839.1
ENSMUST00000006754.7
Ubtf


upstream binding transcription factor, RNA polymerase I


chr9_-_57552760 0.511 ENSMUST00000034856.8
Mpi
mannose phosphate isomerase
chr4_+_127172866 0.503 ENSMUST00000106094.2
Dlgap3
discs, large (Drosophila) homolog-associated protein 3
chr15_-_93336800 0.472 ENSMUST00000080299.6
Yaf2
YY1 associated factor 2
chr4_+_118620799 0.471 ENSMUST00000030501.8
Ebna1bp2
EBNA1 binding protein 2
chrX_+_150588223 0.469 ENSMUST00000153221.1
Pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr17_-_25081138 0.468 ENSMUST00000024984.6
Tmem204
transmembrane protein 204
chr17_-_46032366 0.455 ENSMUST00000071648.5
ENSMUST00000142351.2
ENSMUST00000167860.1
Vegfa


vascular endothelial growth factor A


chr15_+_39076885 0.436 ENSMUST00000067072.3
Cthrc1
collagen triple helix repeat containing 1
chr19_-_23448322 0.433 ENSMUST00000036069.6
Mamdc2
MAM domain containing 2
chr15_-_98607611 0.431 ENSMUST00000096224.4
Adcy6
adenylate cyclase 6
chr11_+_115420138 0.419 ENSMUST00000106533.1
ENSMUST00000123345.1
Kctd2

potassium channel tetramerisation domain containing 2

chr17_-_28486082 0.414 ENSMUST00000079413.3
Fkbp5
FK506 binding protein 5
chr2_+_3114220 0.413 ENSMUST00000072955.5
Fam171a1
family with sequence similarity 171, member A1
chrX_+_101383726 0.405 ENSMUST00000119190.1
Gjb1
gap junction protein, beta 1
chrX_-_7898950 0.370 ENSMUST00000115655.1
ENSMUST00000156741.1
Pqbp1

polyglutamine binding protein 1

chr11_+_4160348 0.362 ENSMUST00000002198.3
Sf3a1
splicing factor 3a, subunit 1
chr15_-_96460838 0.351 ENSMUST00000047835.6
Scaf11
SR-related CTD-associated factor 11
chr14_-_18331855 0.349 ENSMUST00000022296.6
Ube2e1
ubiquitin-conjugating enzyme E2E 1
chr5_+_65537267 0.310 ENSMUST00000122141.1
Ube2k
ubiquitin-conjugating enzyme E2K
chr7_+_83755904 0.308 ENSMUST00000051522.8
ENSMUST00000042280.7
Gm7964

predicted gene 7964

chr18_-_52529692 0.284 ENSMUST00000025409.7
Lox
lysyl oxidase
chr7_+_82867327 0.280 ENSMUST00000082237.5
Mex3b
mex3 homolog B (C. elegans)
chr6_+_116650674 0.273 ENSMUST00000067354.5
ENSMUST00000178241.1
8430408G22Rik

RIKEN cDNA 8430408G22 gene

chr9_+_13621646 0.270 ENSMUST00000034401.8
Maml2
mastermind like 2 (Drosophila)
chr2_+_29869484 0.262 ENSMUST00000047521.6
ENSMUST00000134152.1
Cercam

cerebral endothelial cell adhesion molecule

chr2_-_128967725 0.253 ENSMUST00000099385.2
Gm10762
predicted gene 10762
chr5_-_92278155 0.211 ENSMUST00000159345.1
ENSMUST00000113102.3
Naaa

N-acylethanolamine acid amidase

chr5_-_123684289 0.207 ENSMUST00000111564.1
ENSMUST00000063905.5
Clip1

CAP-GLY domain containing linker protein 1

chr6_-_83775767 0.194 ENSMUST00000014892.6
Tex261
testis expressed gene 261
chr7_-_45870928 0.192 ENSMUST00000146672.1
Grin2d
glutamate receptor, ionotropic, NMDA2D (epsilon 4)
chr19_+_4097392 0.181 ENSMUST00000174514.1
ENSMUST00000174149.1
Cdk2ap2

CDK2-associated protein 2

chrX_-_150588071 0.137 ENSMUST00000140207.1
ENSMUST00000112719.1
ENSMUST00000112727.3
ENSMUST00000112721.3
ENSMUST00000026303.9
Apex2




apurinic/apyrimidinic endonuclease 2




chr10_+_91083036 0.131 ENSMUST00000020149.5
Ikbip
IKBKB interacting protein
chr4_+_148130883 0.112 ENSMUST00000084129.2
Mad2l2
MAD2 mitotic arrest deficient-like 2
chr16_+_34784917 0.109 ENSMUST00000023538.8
Mylk
myosin, light polypeptide kinase
chrX_-_7898864 0.086 ENSMUST00000154552.1
Pqbp1
polyglutamine binding protein 1
chr2_-_93046053 0.075 ENSMUST00000111272.1
ENSMUST00000178666.1
ENSMUST00000147339.1
Prdm11


PR domain containing 11


chr5_-_24601961 0.072 ENSMUST00000030791.7
Smarcd3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr5_-_124352233 0.058 ENSMUST00000111472.1
Cdk2ap1
CDK2 (cyclin-dependent kinase 2)-associated protein 1
chr15_-_27681498 0.053 ENSMUST00000100739.3
Fam105a
family with sequence similarity 105, member A
chr18_-_52529847 0.037 ENSMUST00000171470.1
Lox
lysyl oxidase
chr9_-_14381242 0.035 ENSMUST00000167549.1
Endod1
endonuclease domain containing 1
chrX_-_136741155 0.030 ENSMUST00000166930.1
ENSMUST00000113095.1
ENSMUST00000155207.1
ENSMUST00000080411.6
ENSMUST00000169418.1
Morf4l2




mortality factor 4 like 2




chr5_+_121795034 0.024 ENSMUST00000162327.1
Atxn2
ataxin 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 22.7 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
2.3 9.2 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
2.2 11.0 GO:0021764 amygdala development(GO:0021764)
2.1 6.3 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
1.7 10.2 GO:0014719 skeletal muscle satellite cell activation(GO:0014719)
1.4 9.8 GO:0035331 negative regulation of hippo signaling(GO:0035331)
1.1 9.7 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
1.0 5.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
1.0 5.0 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
1.0 2.9 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.9 17.8 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.9 2.6 GO:2000224 regulation of testosterone biosynthetic process(GO:2000224)
0.8 2.5 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.7 5.1 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.7 2.9 GO:2000546 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.7 2.1 GO:1905203 regulation of connective tissue replacement(GO:1905203)
0.6 2.4 GO:0015889 cobalamin transport(GO:0015889)
0.5 2.7 GO:0006447 regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994)
0.5 1.6 GO:1902336 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336)
0.5 2.6 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.5 9.4 GO:0048368 lateral mesoderm development(GO:0048368)
0.5 6.0 GO:0038092 nodal signaling pathway(GO:0038092)
0.4 1.3 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.4 1.7 GO:0006751 glutathione catabolic process(GO:0006751)
0.4 2.3 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.3 1.2 GO:0035811 negative regulation of urine volume(GO:0035811)
0.3 1.5 GO:0019230 proprioception(GO:0019230)
0.3 0.9 GO:0071492 cellular response to UV-A(GO:0071492)
0.3 4.5 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.3 1.4 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.3 0.8 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 1.2 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.2 1.1 GO:0002339 B cell selection(GO:0002339)
0.2 3.1 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090)
0.2 5.3 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.2 5.9 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.2 4.5 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.2 0.5 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.2 0.7 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.2 7.4 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.2 2.4 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.2 0.5 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.2 0.9 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.1 0.4 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 3.2 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.9 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.1 1.8 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.1 1.2 GO:0033572 transferrin transport(GO:0033572)
0.1 3.5 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.1 1.3 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.1 2.5 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.1 1.0 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.1 1.5 GO:0016180 snRNA processing(GO:0016180)
0.1 0.1 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.1 0.5 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.1 1.0 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.1 1.4 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.1 0.5 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 3.0 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.1 3.0 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.1 0.2 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 1.5 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.2 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.0 1.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.4 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.0 1.0 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 2.4 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 1.4 GO:1901998 toxin transport(GO:1901998)
0.0 0.4 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.0 0.3 GO:0072697 protein localization to cell cortex(GO:0072697)
0.0 0.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 3.6 GO:0006342 chromatin silencing(GO:0006342)
0.0 2.8 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 1.9 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 1.9 GO:0032543 mitochondrial translation(GO:0032543)
0.0 2.9 GO:0051225 spindle assembly(GO:0051225)
0.0 2.7 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 1.4 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.5 GO:0001945 lymph vessel development(GO:0001945)
0.0 0.5 GO:0034063 stress granule assembly(GO:0034063)
0.0 3.3 GO:0070507 regulation of microtubule cytoskeleton organization(GO:0070507)
0.0 2.1 GO:0009267 cellular response to starvation(GO:0009267)
0.0 0.2 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 1.3 GO:0021954 central nervous system neuron development(GO:0021954)
0.0 0.6 GO:0003341 cilium movement(GO:0003341)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 9.4 GO:0071149 TEAD-2-YAP complex(GO:0071149)
1.8 5.3 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.8 5.0 GO:0035976 AP1 complex(GO:0035976)
0.5 19.5 GO:0060077 inhibitory synapse(GO:0060077)
0.4 12.7 GO:0000788 nuclear nucleosome(GO:0000788)
0.4 2.9 GO:0070652 HAUS complex(GO:0070652)
0.4 8.1 GO:0001891 phagocytic cup(GO:0001891)
0.3 7.0 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.3 3.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.3 0.8 GO:0005588 collagen type V trimer(GO:0005588)
0.2 3.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.2 0.5 GO:0036128 CatSper complex(GO:0036128)
0.2 6.4 GO:0000786 nucleosome(GO:0000786)
0.2 0.5 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.1 5.3 GO:0035371 microtubule plus-end(GO:0035371)
0.1 1.9 GO:0042788 polysomal ribosome(GO:0042788)
0.1 1.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 1.0 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 1.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 1.5 GO:0032039 integrator complex(GO:0032039)
0.1 2.8 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 9.8 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 1.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 1.3 GO:0005686 U2 snRNP(GO:0005686)
0.1 1.2 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.5 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.7 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 1.9 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.5 GO:0005839 proteasome core complex(GO:0005839)
0.0 2.2 GO:0005581 collagen trimer(GO:0005581)
0.0 0.4 GO:0005922 connexon complex(GO:0005922)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 1.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.4 GO:0031528 microvillus membrane(GO:0031528)
0.0 1.2 GO:0016235 aggresome(GO:0016235)
0.0 3.4 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 2.1 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)
0.0 2.8 GO:0001650 fibrillar center(GO:0001650)
0.0 2.7 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 7.0 GO:0005874 microtubule(GO:0005874)
0.0 1.9 GO:0055037 recycling endosome(GO:0055037)
0.0 3.4 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.6 GO:0005930 axoneme(GO:0005930)
0.0 2.0 GO:0005802 trans-Golgi network(GO:0005802)
0.0 6.8 GO:0016604 nuclear body(GO:0016604)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 22.7 GO:0004351 glutamate decarboxylase activity(GO:0004351)
2.1 6.3 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
1.6 6.3 GO:0050436 microfibril binding(GO:0050436)
1.5 4.5 GO:0030158 protein xylosyltransferase activity(GO:0030158)
1.3 8.8 GO:0001849 complement component C1q binding(GO:0001849)
1.0 2.9 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.8 4.9 GO:0043426 MRF binding(GO:0043426)
0.8 9.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.7 2.6 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.5 1.6 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.5 10.2 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.5 9.4 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.4 2.6 GO:0001972 retinoic acid binding(GO:0001972)
0.4 6.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.3 2.4 GO:0031419 cobalamin binding(GO:0031419)
0.3 5.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.3 1.5 GO:0098634 protein binding involved in cell-matrix adhesion(GO:0098634)
0.3 2.9 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.3 4.5 GO:0030957 Tat protein binding(GO:0030957)
0.3 6.0 GO:0070410 co-SMAD binding(GO:0070410)
0.3 5.0 GO:0035497 cAMP response element binding(GO:0035497)
0.2 1.7 GO:0008242 omega peptidase activity(GO:0008242)
0.2 11.0 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.2 3.7 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 6.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.2 3.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.2 1.4 GO:0031432 titin binding(GO:0031432)
0.2 1.9 GO:0044548 S100 protein binding(GO:0044548)
0.2 1.4 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.2 3.7 GO:0070628 proteasome binding(GO:0070628)
0.2 2.5 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 1.1 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.5 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.1 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 1.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 17.7 GO:0042393 histone binding(GO:0042393)
0.1 0.4 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 5.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.5 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 0.6 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.1 4.5 GO:0019955 cytokine binding(GO:0019955)
0.1 0.3 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 2.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.9 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.5 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.1 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.0 1.4 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 8.2 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.4 GO:0005243 gap junction channel activity(GO:0005243)
0.0 1.0 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.5 GO:0051861 glycolipid binding(GO:0051861)
0.0 0.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 7.6 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.0 GO:0030332 cyclin binding(GO:0030332)
0.0 1.4 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 3.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.2 GO:0043022 ribosome binding(GO:0043022)
0.0 2.1 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 1.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.9 GO:0004222 metalloendopeptidase activity(GO:0004222)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.0 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.3 5.5 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.3 4.9 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.2 9.2 PID_BMP_PATHWAY BMP receptor signaling
0.1 1.6 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.1 3.7 PID_ALK1_PATHWAY ALK1 signaling events
0.1 5.2 PID_AURORA_B_PATHWAY Aurora B signaling
0.1 6.6 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.1 3.6 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.1 1.8 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.1 2.7 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 6.0 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.1 1.9 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.1 2.1 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.1 9.2 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 2.5 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 2.2 NABA_COLLAGENS Genes encoding collagen proteins
0.0 4.5 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 2.6 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 0.4 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 1.2 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 1.5 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 22.7 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.6 6.3 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.5 16.9 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.4 12.2 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.4 2.9 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.3 2.7 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.3 9.2 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.3 18.4 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.3 5.0 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.2 4.9 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.2 6.0 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2 2.1 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.2 5.1 REACTOME_KINESINS Genes involved in Kinesins
0.1 1.3 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 1.6 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 3.1 REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.1 1.0 REACTOME_PECAM1_INTERACTIONS Genes involved in PECAM1 interactions
0.1 0.5 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 2.6 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.1 5.5 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 1.3 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 1.7 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 2.8 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 2.6 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 2.2 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 3.3 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.4 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 5.8 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.5 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.9 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 1.4 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.3 REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 1.0 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 2.4 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.0 0.5 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.5 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.5 REACTOME_AUTODEGRADATION_OF_CDH1_BY_CDH1_APC_C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C