Motif ID: Klf13

Z-value: 0.588


Transcription factors associated with Klf13:

Gene SymbolEntrez IDGene Name
Klf13 ENSMUSG00000052040.9 Klf13

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Klf13mm10_v2_chr7_-_63938862_63938933-0.211.9e-01Click!


Activity profile for motif Klf13.

activity profile for motif Klf13


Sorted Z-values histogram for motif Klf13

Sorted Z-values for motif Klf13



Network of associatons between targets according to the STRING database.



First level regulatory network of Klf13

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_126736236 3.856 ENSMUST00000048194.7
Tfap2e
transcription factor AP-2, epsilon
chr17_-_87282771 1.456 ENSMUST00000161759.1
4833418N02Rik
RIKEN cDNA 4833418N02 gene
chr19_+_56722372 1.455 ENSMUST00000038949.4
Adrb1
adrenergic receptor, beta 1
chr17_+_87282880 1.349 ENSMUST00000041110.5
ENSMUST00000125875.1
Ttc7

tetratricopeptide repeat domain 7

chr12_-_14152038 1.304 ENSMUST00000020926.6
Fam84a
family with sequence similarity 84, member A
chr5_-_139736291 1.240 ENSMUST00000044642.10
Micall2
MICAL-like 2
chr7_-_16874845 1.141 ENSMUST00000181501.1
9330104G04Rik
RIKEN cDNA 9330104G04 gene
chr2_+_25262589 1.135 ENSMUST00000114336.3
Tprn
taperin
chr11_+_70026815 1.130 ENSMUST00000135916.2
Dlg4
discs, large homolog 4 (Drosophila)
chr15_-_64922290 1.106 ENSMUST00000023007.5
Adcy8
adenylate cyclase 8
chr17_-_87282793 1.070 ENSMUST00000146560.2
4833418N02Rik
RIKEN cDNA 4833418N02 gene
chr14_-_76010863 1.058 ENSMUST00000088922.4
Gtf2f2
general transcription factor IIF, polypeptide 2
chr18_+_37955544 1.049 ENSMUST00000070709.2
ENSMUST00000177058.1
ENSMUST00000169360.2
ENSMUST00000163591.2
ENSMUST00000091932.5
Rell2




RELT-like 2




chr12_-_79172609 0.975 ENSMUST00000055262.6
Vti1b
vesicle transport through interaction with t-SNAREs 1B
chr8_-_94876269 0.972 ENSMUST00000046461.7
Dok4
docking protein 4
chr7_+_16875302 0.967 ENSMUST00000108493.1
Dact3
dapper homolog 3, antagonist of beta-catenin (xenopus)
chr18_+_37955126 0.925 ENSMUST00000176902.1
ENSMUST00000176104.1
Rell2

RELT-like 2

chr17_-_35910032 0.888 ENSMUST00000141662.1
ENSMUST00000056034.6
ENSMUST00000077494.6
ENSMUST00000149277.1
ENSMUST00000061052.5
Atat1




alpha tubulin acetyltransferase 1




chr18_+_12168711 0.822 ENSMUST00000025276.8
3110002H16Rik
RIKEN cDNA 3110002H16 gene
chr10_-_62340514 0.800 ENSMUST00000099691.4
Hk1
hexokinase 1
chr9_-_18473559 0.761 ENSMUST00000034647.4
Zfp558
zinc finger protein 558
chr19_-_42129043 0.738 ENSMUST00000018965.3
Avpi1
arginine vasopressin-induced 1
chr19_-_42128982 0.723 ENSMUST00000161873.1
Avpi1
arginine vasopressin-induced 1
chr11_+_116532441 0.715 ENSMUST00000106386.1
ENSMUST00000145737.1
ENSMUST00000155102.1
ENSMUST00000063446.6
Sphk1



sphingosine kinase 1



chr11_-_76399107 0.676 ENSMUST00000021204.3
Nxn
nucleoredoxin
chr2_+_120977017 0.659 ENSMUST00000067582.7
Tmem62
transmembrane protein 62
chr4_-_117133953 0.656 ENSMUST00000076859.5
Plk3
polo-like kinase 3
chr6_+_83795022 0.650 ENSMUST00000113851.1
Nagk
N-acetylglucosamine kinase
chr17_+_56717759 0.639 ENSMUST00000002452.6
Ndufa11
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 11
chr5_-_137741102 0.632 ENSMUST00000149512.1
Nyap1
neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1
chr5_+_35757875 0.622 ENSMUST00000101280.3
ENSMUST00000054598.5
ENSMUST00000114205.1
ENSMUST00000114206.2
Ablim2



actin-binding LIM protein 2



chr11_+_44617310 0.613 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
Ebf1


early B cell factor 1


chr2_-_73892619 0.604 ENSMUST00000112007.1
ENSMUST00000112016.2
Atf2

activating transcription factor 2

chr7_-_30563184 0.602 ENSMUST00000043898.6
Psenen
presenilin enhancer 2 homolog (C. elegans)
chr5_-_137741601 0.593 ENSMUST00000119498.1
ENSMUST00000061789.7
Nyap1

neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1

chr6_+_83795205 0.592 ENSMUST00000113850.1
Nagk
N-acetylglucosamine kinase
chr6_+_83794974 0.590 ENSMUST00000037376.7
Nagk
N-acetylglucosamine kinase
chr2_-_73892530 0.588 ENSMUST00000136958.1
ENSMUST00000112010.2
ENSMUST00000128531.1
ENSMUST00000112017.1
Atf2



activating transcription factor 2



chr5_-_137502402 0.579 ENSMUST00000111035.1
ENSMUST00000031728.4
Pop7

processing of precursor 7, ribonuclease P family, (S. cerevisiae)

chr2_-_73892588 0.567 ENSMUST00000154456.1
ENSMUST00000090802.4
ENSMUST00000055833.5
Atf2


activating transcription factor 2


chr7_-_27178835 0.542 ENSMUST00000093040.6
Rab4b
RAB4B, member RAS oncogene family
chr5_-_138263942 0.526 ENSMUST00000048421.7
ENSMUST00000164203.1
BC037034
BC037034
cDNA sequence BC037034
cDNA sequence BC037034
chr10_-_81167896 0.496 ENSMUST00000005064.7
Pias4
protein inhibitor of activated STAT 4
chr7_+_25619404 0.488 ENSMUST00000077338.5
ENSMUST00000085953.3
Atp5sl

ATP5S-like

chr1_-_74600564 0.465 ENSMUST00000127938.1
ENSMUST00000154874.1
Rnf25

ring finger protein 25

chr2_+_167538192 0.454 ENSMUST00000052631.7
Snai1
snail homolog 1 (Drosophila)
chr17_-_35909626 0.422 ENSMUST00000141132.1
Atat1
alpha tubulin acetyltransferase 1
chr7_+_18925863 0.407 ENSMUST00000172835.1
ENSMUST00000032571.8
Nova2

neuro-oncological ventral antigen 2

chr5_-_138264013 0.399 ENSMUST00000161604.1
ENSMUST00000163268.1
BC037034
BC037034
cDNA sequence BC037034
cDNA sequence BC037034
chr12_+_72085847 0.399 ENSMUST00000117449.1
ENSMUST00000057257.8
Jkamp

JNK1/MAPK8-associated membrane protein

chrX_-_8252304 0.374 ENSMUST00000115594.1
Ftsj1
FtsJ homolog 1 (E. coli)
chr8_-_71486037 0.361 ENSMUST00000093450.4
Ano8
anoctamin 8
chr16_+_4726357 0.357 ENSMUST00000154117.1
ENSMUST00000004172.8
Hmox2

heme oxygenase (decycling) 2

chrX_-_8252334 0.353 ENSMUST00000115595.1
ENSMUST00000033513.3
Ftsj1

FtsJ homolog 1 (E. coli)

chr17_+_35059035 0.344 ENSMUST00000007255.6
ENSMUST00000174493.1
Ddah2

dimethylarginine dimethylaminohydrolase 2

chr14_-_55591077 0.342 ENSMUST00000161807.1
ENSMUST00000111378.3
ENSMUST00000159687.1
Psme2


proteasome (prosome, macropain) activator subunit 2 (PA28 beta)


chrX_-_150813637 0.303 ENSMUST00000112700.1
Maged2
melanoma antigen, family D, 2
chr14_+_70100083 0.303 ENSMUST00000022680.7
Bin3
bridging integrator 3
chr15_+_85037062 0.302 ENSMUST00000023069.7
Fam118a
family with sequence similarity 118, member A
chr13_-_49215978 0.300 ENSMUST00000048946.6
1110007C09Rik
RIKEN cDNA 1110007C09 gene
chr14_+_54426902 0.294 ENSMUST00000010550.7
Mrpl52
mitochondrial ribosomal protein L52
chr9_+_70012540 0.278 ENSMUST00000118198.1
ENSMUST00000119905.1
ENSMUST00000119413.1
ENSMUST00000140305.1
ENSMUST00000122087.1
Gtf2a2




general transcription factor II A, 2




chr8_+_83608175 0.268 ENSMUST00000005620.8
Dnajb1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr17_+_34564268 0.249 ENSMUST00000015612.7
Notch4
notch 4
chr19_+_46761578 0.246 ENSMUST00000077666.4
ENSMUST00000099373.4
Cnnm2

cyclin M2

chr18_+_67343564 0.241 ENSMUST00000025404.8
Cidea
cell death-inducing DNA fragmentation factor, alpha subunit-like effector A
chr15_-_99251929 0.228 ENSMUST00000041190.9
ENSMUST00000163506.1
Mcrs1

microspherule protein 1

chr2_-_35200923 0.219 ENSMUST00000028238.8
ENSMUST00000113025.1
Rab14

RAB14, member RAS oncogene family

chr7_+_101663633 0.212 ENSMUST00000001884.7
Clpb
ClpB caseinolytic peptidase B
chr10_-_81378459 0.188 ENSMUST00000140901.1
Fzr1
fizzy/cell division cycle 20 related 1 (Drosophila)
chr18_-_46597299 0.187 ENSMUST00000036030.7
Tmed7
transmembrane emp24 protein transport domain containing 7
chr7_-_122021143 0.171 ENSMUST00000033160.8
Gga2
golgi associated, gamma adaptin ear containing, ARF binding protein 2
chr14_-_118706180 0.168 ENSMUST00000036554.6
ENSMUST00000166646.1
Abcc4

ATP-binding cassette, sub-family C (CFTR/MRP), member 4

chr6_-_82652856 0.167 ENSMUST00000160281.1
ENSMUST00000095786.5
Pole4

polymerase (DNA-directed), epsilon 4 (p12 subunit)

chr4_-_150008977 0.167 ENSMUST00000030830.3
H6pd
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr3_-_90509450 0.166 ENSMUST00000107343.1
ENSMUST00000001043.7
ENSMUST00000107344.1
ENSMUST00000076639.4
ENSMUST00000107346.1
ENSMUST00000146740.1
ENSMUST00000107342.1
ENSMUST00000049937.6
Chtop







chromatin target of PRMT1







chr6_-_119417479 0.153 ENSMUST00000032272.6
Adipor2
adiponectin receptor 2
chr16_+_17619341 0.148 ENSMUST00000006053.6
ENSMUST00000171435.1
ENSMUST00000163476.1
ENSMUST00000168101.1
ENSMUST00000165363.1
ENSMUST00000169662.1
ENSMUST00000090159.4
ENSMUST00000172182.1
ENSMUST00000163592.1
Smpd4








sphingomyelin phosphodiesterase 4








chr1_-_36445248 0.143 ENSMUST00000125304.1
ENSMUST00000115011.1
Lman2l

lectin, mannose-binding 2-like

chr8_-_36249292 0.140 ENSMUST00000065297.5
Lonrf1
LON peptidase N-terminal domain and ring finger 1
chr4_-_119422355 0.134 ENSMUST00000106316.1
ENSMUST00000030385.6
Ppcs

phosphopantothenoylcysteine synthetase

chr2_+_156196642 0.130 ENSMUST00000037401.8
Phf20
PHD finger protein 20
chr10_-_127211528 0.124 ENSMUST00000013970.7
Pip4k2c
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr5_+_135689036 0.119 ENSMUST00000005651.6
ENSMUST00000122113.1
Por

P450 (cytochrome) oxidoreductase

chr2_+_32288244 0.111 ENSMUST00000113377.1
ENSMUST00000100194.2
Golga2

golgi autoantigen, golgin subfamily a, 2

chr19_-_5610038 0.110 ENSMUST00000113641.2
Kat5
K(lysine) acetyltransferase 5
chr12_-_72085393 0.109 ENSMUST00000019862.2
L3hypdh
L-3-hydroxyproline dehydratase (trans-)
chr15_-_11995998 0.107 ENSMUST00000022816.8
Sub1
SUB1 homolog (S. cerevisiae)
chr4_-_43040279 0.105 ENSMUST00000107958.1
ENSMUST00000107959.1
ENSMUST00000152846.1
Fam214b


family with sequence similarity 214, member B


chr17_-_56757516 0.103 ENSMUST00000044752.5
Nrtn
neurturin
chr18_-_46597480 0.098 ENSMUST00000151189.1
Tmed7
transmembrane emp24 protein transport domain containing 7
chr7_+_3694512 0.094 ENSMUST00000108627.3
Tsen34
tRNA splicing endonuclease 34 homolog (S. cerevisiae)
chr2_-_24935148 0.093 ENSMUST00000102935.3
ENSMUST00000133934.1
ENSMUST00000028349.7
Arrdc1


arrestin domain containing 1


chr8_+_3631109 0.093 ENSMUST00000004745.8
Stxbp2
syntaxin binding protein 2
chr10_-_40257648 0.092 ENSMUST00000019982.7
Gtf3c6
general transcription factor IIIC, polypeptide 6, alpha
chr19_-_4811508 0.088 ENSMUST00000180008.1
ENSMUST00000113793.3
ENSMUST00000006625.7
ENSMUST00000179909.1
ENSMUST00000172000.2
Rbm14


Gm21992

RNA binding motif protein 14


predicted gene 21992

chr4_+_45018583 0.078 ENSMUST00000133157.1
ENSMUST00000029999.8
ENSMUST00000107814.3
Polr1e


polymerase (RNA) I polypeptide E


chr8_+_69832633 0.075 ENSMUST00000131637.2
ENSMUST00000081503.6
Pbx4

pre B cell leukemia homeobox 4

chr18_+_46597698 0.070 ENSMUST00000078079.3
ENSMUST00000168382.1
Eif1a

eukaryotic translation initiation factor 1A

chr18_-_37954958 0.069 ENSMUST00000043498.7
Hdac3
histone deacetylase 3
chr11_+_69964758 0.058 ENSMUST00000108597.1
ENSMUST00000060651.5
ENSMUST00000108596.1
Cldn7


claudin 7


chr7_-_16614937 0.039 ENSMUST00000171937.1
ENSMUST00000075845.4
Grlf1

glucocorticoid receptor DNA binding factor 1

chr5_-_38220400 0.038 ENSMUST00000114113.1
ENSMUST00000094833.3
Zbtb49

zinc finger and BTB domain containing 49

chr7_+_43444104 0.034 ENSMUST00000004729.3
Etfb
electron transferring flavoprotein, beta polypeptide
chr16_+_17619503 0.032 ENSMUST00000165092.1
Smpd4
sphingomyelin phosphodiesterase 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.5 1.5 GO:1900133 renin secretion into blood stream(GO:0002001) regulation of renin secretion into blood stream(GO:1900133)
0.4 1.3 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.3 1.8 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.2 0.5 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.1 0.8 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 0.5 GO:0010957 negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137) regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.3 GO:0009826 unidimensional cell growth(GO:0009826)
0.1 1.0 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.4 GO:0006788 heme oxidation(GO:0006788)
0.1 1.1 GO:0099628 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.1 0.8 GO:0090166 Golgi disassembly(GO:0090166)
0.1 1.1 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 0.7 GO:0046512 sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.1 0.2 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 1.0 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 0.3 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0 0.6 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.2 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.0 0.6 GO:0007220 Notch receptor processing(GO:0007220)
0.0 1.5 GO:0032456 endocytic recycling(GO:0032456)
0.0 1.1 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 0.3 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.2 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.0 0.1 GO:0046210 nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.0 1.3 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.3 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.1 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.1 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.0 0.3 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.2 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0 0.2 GO:0061042 vascular wound healing(GO:0061042)
0.0 0.2 GO:0006855 drug transmembrane transport(GO:0006855)
0.0 0.6 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 2.0 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.3 GO:0019884 antigen processing and presentation of exogenous antigen(GO:0019884)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.1 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.1 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.2 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.1 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 1.4 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.7 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.7 GO:0045454 cell redox homeostasis(GO:0045454)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 1.3 GO:0097427 microtubule bundle(GO:0097427)
0.1 0.6 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 0.6 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 0.3 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 1.1 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 1.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 0.2 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 0.3 GO:0099524 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.0 1.8 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.0 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.8 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.2 GO:0097208 alveolar lamellar body(GO:0097208)
0.0 1.1 GO:0032420 stereocilium(GO:0032420)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 2.0 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.6 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 1.2 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.5 1.5 GO:0051379 epinephrine binding(GO:0051379)
0.2 1.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.2 1.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.2 0.7 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.2 0.8 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 1.8 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 1.1 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 0.7 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 1.0 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 1.1 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.1 0.4 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 1.2 GO:0031005 filamin binding(GO:0031005)
0.1 1.0 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.5 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.2 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.1 0.6 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.6 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.4 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.2 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.0 0.3 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0036361 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.0 0.7 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.1 GO:0016708 nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726)
0.0 2.0 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 1.0 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.2 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.1 GO:0001179 RNA polymerase I transcription factor binding(GO:0001179)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 3.9 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.1 2.7 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.8 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.7 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.0 0.6 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 1.0 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.5 PID_IFNG_PATHWAY IFN-gamma pathway
0.0 0.8 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 1.8 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 1.1 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 1.1 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.6 REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.8 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.0 0.7 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway