Motif ID: Creb3

Z-value: 0.759


Transcription factors associated with Creb3:

Gene SymbolEntrez IDGene Name
Creb3 ENSMUSG00000028466.9 Creb3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Creb3mm10_v2_chr4_+_43562672_43562947-0.481.6e-03Click!


Activity profile for motif Creb3.

activity profile for motif Creb3


Sorted Z-values histogram for motif Creb3

Sorted Z-values for motif Creb3



Network of associatons between targets according to the STRING database.



First level regulatory network of Creb3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_71546745 7.586 ENSMUST00000024159.6
Dlx2
distal-less homeobox 2
chr14_-_79301623 6.881 ENSMUST00000022595.7
Rgcc
regulator of cell cycle
chrX_-_60893430 6.318 ENSMUST00000135107.2
Sox3
SRY-box containing gene 3
chr5_-_135251209 6.056 ENSMUST00000062572.2
Fzd9
frizzled homolog 9 (Drosophila)
chr15_+_79516396 6.053 ENSMUST00000010974.7
Kdelr3
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr7_-_45092130 5.312 ENSMUST00000148175.1
Rcn3
reticulocalbin 3, EF-hand calcium binding domain
chr7_-_45091713 5.285 ENSMUST00000141576.1
Rcn3
reticulocalbin 3, EF-hand calcium binding domain
chr2_-_105399286 4.588 ENSMUST00000006128.6
Rcn1
reticulocalbin 1
chr7_-_25250720 3.572 ENSMUST00000116343.2
ENSMUST00000045847.8
Erf

Ets2 repressor factor

chr11_-_94653964 3.475 ENSMUST00000039949.4
Eme1
essential meiotic endonuclease 1 homolog 1 (S. pombe)
chr2_-_150668198 3.065 ENSMUST00000028944.3
Acss1
acyl-CoA synthetase short-chain family member 1
chr4_+_3938888 3.049 ENSMUST00000121110.1
ENSMUST00000108386.1
ENSMUST00000149544.1
Chchd7


coiled-coil-helix-coiled-coil-helix domain containing 7


chr18_+_84720019 2.879 ENSMUST00000161429.1
ENSMUST00000052501.1
Fam69c

family with sequence similarity 69, member C

chr3_-_36571952 2.808 ENSMUST00000029270.3
Ccna2
cyclin A2
chr7_-_45092198 2.649 ENSMUST00000140449.1
ENSMUST00000117546.1
ENSMUST00000019683.3
Rcn3


reticulocalbin 3, EF-hand calcium binding domain


chr7_-_144939823 2.556 ENSMUST00000093962.4
Ccnd1
cyclin D1
chr7_+_128523576 2.361 ENSMUST00000033136.7
Bag3
BCL2-associated athanogene 3
chr2_+_119112793 2.347 ENSMUST00000140939.1
ENSMUST00000028795.3
Rad51

RAD51 homolog

chr4_-_117182623 2.324 ENSMUST00000065896.2
Kif2c
kinesin family member 2C
chr4_+_47474652 2.259 ENSMUST00000065678.5
ENSMUST00000137461.1
ENSMUST00000125622.1
Sec61b


Sec61 beta subunit


chr10_+_127041931 2.019 ENSMUST00000006915.7
ENSMUST00000120542.1
Mettl1

methyltransferase like 1

chr13_-_23762378 1.978 ENSMUST00000091701.2
Hist1h3a
histone cluster 1, H3a
chr13_-_38528412 1.969 ENSMUST00000035988.8
Txndc5
thioredoxin domain containing 5
chr7_-_143460989 1.913 ENSMUST00000167912.1
ENSMUST00000037287.6
Cdkn1c

cyclin-dependent kinase inhibitor 1C (P57)

chr6_+_83115495 1.868 ENSMUST00000032114.7
Mogs
mannosyl-oligosaccharide glucosidase
chr12_-_69184056 1.653 ENSMUST00000054544.6
Rpl36al
ribosomal protein L36A-like
chr6_-_108185552 1.621 ENSMUST00000167338.1
ENSMUST00000172188.1
ENSMUST00000032191.9
Sumf1


sulfatase modifying factor 1


chr5_-_149053038 1.614 ENSMUST00000085546.6
Hmgb1
high mobility group box 1
chr3_+_116878227 1.598 ENSMUST00000040260.6
Frrs1
ferric-chelate reductase 1
chr4_+_3938904 1.567 ENSMUST00000120732.1
ENSMUST00000041122.4
ENSMUST00000121651.1
ENSMUST00000121210.1
ENSMUST00000119307.1
ENSMUST00000123769.1
Chchd7





coiled-coil-helix-coiled-coil-helix domain containing 7





chr12_-_69183986 1.434 ENSMUST00000110620.1
ENSMUST00000110619.1
Rpl36al

ribosomal protein L36A-like

chr7_-_48881596 1.430 ENSMUST00000119223.1
E2f8
E2F transcription factor 8
chr9_-_83146601 1.423 ENSMUST00000162246.2
ENSMUST00000161796.2
Hmgn3

high mobility group nucleosomal binding domain 3

chr10_+_41519493 1.386 ENSMUST00000019962.8
Cd164
CD164 antigen
chr9_-_20976762 1.367 ENSMUST00000054197.5
S1pr2
sphingosine-1-phosphate receptor 2
chr19_+_8967031 1.347 ENSMUST00000052248.7
Eef1g
eukaryotic translation elongation factor 1 gamma
chr11_-_113751813 1.340 ENSMUST00000053536.4
Cdc42ep4
CDC42 effector protein (Rho GTPase binding) 4
chr4_-_150909812 1.284 ENSMUST00000134751.1
ENSMUST00000030805.7
Park7

Parkinson disease (autosomal recessive, early onset) 7

chr9_+_84423958 1.282 ENSMUST00000177716.1
Gm8226
predicted gene 8226
chr12_-_69159109 1.234 ENSMUST00000037023.8
Rps29
ribosomal protein S29
chr3_+_88206786 1.234 ENSMUST00000181134.1
ENSMUST00000181550.1
Gm3764

predicted gene 3764

chr10_+_79682169 1.232 ENSMUST00000020550.5
Cdc34
cell division cycle 34
chrX_+_36328353 1.201 ENSMUST00000016383.3
Lonrf3
LON peptidase N-terminal domain and ring finger 3
chr11_+_70000578 1.198 ENSMUST00000019362.8
Dvl2
dishevelled 2, dsh homolog (Drosophila)
chr17_-_10319324 1.197 ENSMUST00000097414.3
ENSMUST00000042296.7
Qk

quaking

chr2_-_23155864 1.140 ENSMUST00000028119.6
Mastl
microtubule associated serine/threonine kinase-like
chr11_-_120549695 1.138 ENSMUST00000034913.4
Fam195b
family with sequence similarity 195, member B
chr11_-_113751309 1.132 ENSMUST00000106616.1
Cdc42ep4
CDC42 effector protein (Rho GTPase binding) 4
chr13_+_55321991 1.089 ENSMUST00000021942.6
Prelid1
PRELI domain containing 1
chr18_-_84685615 1.079 ENSMUST00000025546.9
Cndp2
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr11_+_94653767 1.059 ENSMUST00000025278.7
Mrpl27
mitochondrial ribosomal protein L27
chr9_+_108339048 1.059 ENSMUST00000082429.5
Gpx1
glutathione peroxidase 1
chr4_+_153957230 1.049 ENSMUST00000058393.2
ENSMUST00000105645.2
A430005L14Rik

RIKEN cDNA A430005L14 gene

chr3_+_129213920 1.037 ENSMUST00000042587.10
Pitx2
paired-like homeodomain transcription factor 2
chr14_-_26638183 1.027 ENSMUST00000166902.1
4930570N19Rik
RIKEN cDNA 4930570N19 gene
chr19_+_6057925 1.012 ENSMUST00000179142.1
Fau
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)
chr5_+_45520221 1.009 ENSMUST00000156481.1
ENSMUST00000119579.1
ENSMUST00000118833.1
Med28


mediator of RNA polymerase II transcription, subunit 28 homolog (yeast)


chrX_+_74313014 0.974 ENSMUST00000114160.1
Fam50a
family with sequence similarity 50, member A
chr19_+_6057888 0.959 ENSMUST00000043074.5
ENSMUST00000178310.1
Fau

Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)

chr1_-_13589717 0.958 ENSMUST00000027068.4
Tram1
translocating chain-associating membrane protein 1
chr7_-_118491912 0.957 ENSMUST00000178344.1
Itpripl2
inositol 1,4,5-triphosphate receptor interacting protein-like 2
chr2_+_29890534 0.951 ENSMUST00000113764.3
Odf2
outer dense fiber of sperm tails 2
chr17_-_36958533 0.950 ENSMUST00000172518.1
Znrd1
zinc ribbon domain containing, 1
chr13_-_76098606 0.933 ENSMUST00000120573.1
Arsk
arylsulfatase K
chr19_+_6910119 0.929 ENSMUST00000174786.1
Trmt112
tRNA methyltransferase 11-2
chr11_+_69935796 0.918 ENSMUST00000018698.5
Ybx2
Y box protein 2
chr4_+_109676568 0.908 ENSMUST00000102724.4
Faf1
Fas-associated factor 1
chr9_+_44379490 0.896 ENSMUST00000066601.6
Hyou1
hypoxia up-regulated 1
chr3_-_37724321 0.891 ENSMUST00000108105.1
ENSMUST00000079755.4
ENSMUST00000099128.1
Gm5148


predicted gene 5148


chr11_-_69981242 0.887 ENSMUST00000108594.1
Elp5
elongator acetyltransferase complex subunit 5
chr10_-_53630439 0.858 ENSMUST00000075540.5
Mcm9
minichromosome maintenance complex component 9
chr11_-_116274102 0.845 ENSMUST00000106425.3
Srp68
signal recognition particle 68
chr19_+_6909692 0.823 ENSMUST00000088257.7
Trmt112
tRNA methyltransferase 11-2
chr3_+_88207308 0.817 ENSMUST00000180582.1
Gm3764
predicted gene 3764
chr7_-_45466894 0.816 ENSMUST00000033093.8
Bax
BCL2-associated X protein
chr11_-_116274197 0.814 ENSMUST00000021133.9
Srp68
signal recognition particle 68
chr5_-_30945393 0.812 ENSMUST00000031051.6
Cgref1
cell growth regulator with EF hand domain 1
chr11_-_88718223 0.810 ENSMUST00000107909.1
Msi2
musashi RNA-binding protein 2
chr4_-_134245579 0.809 ENSMUST00000030644.7
Zfp593
zinc finger protein 593
chr4_+_153957247 0.782 ENSMUST00000141493.1
A430005L14Rik
RIKEN cDNA A430005L14 gene
chr4_-_108406676 0.773 ENSMUST00000184609.1
Gpx7
glutathione peroxidase 7
chr4_+_128654686 0.772 ENSMUST00000030588.6
ENSMUST00000136377.1
Phc2

polyhomeotic-like 2 (Drosophila)

chr9_+_44379536 0.769 ENSMUST00000161318.1
ENSMUST00000160902.1
Hyou1

hypoxia up-regulated 1

chr6_+_48593883 0.768 ENSMUST00000154010.1
ENSMUST00000163452.1
ENSMUST00000118229.1
ENSMUST00000009420.8
Repin1



replication initiator 1



chr1_+_74791516 0.766 ENSMUST00000006718.8
Wnt10a
wingless related MMTV integration site 10a
chr16_-_94370695 0.761 ENSMUST00000113906.2
Pigp
phosphatidylinositol glycan anchor biosynthesis, class P
chr9_+_96895617 0.752 ENSMUST00000071781.6
Gm10123
predicted pseudogene 10123
chr19_-_6057736 0.751 ENSMUST00000007482.6
Mrpl49
mitochondrial ribosomal protein L49
chr11_-_69980468 0.739 ENSMUST00000143175.1
Elp5
elongator acetyltransferase complex subunit 5
chrX_-_74373260 0.734 ENSMUST00000073067.4
ENSMUST00000037967.5
Slc10a3

solute carrier family 10 (sodium/bile acid cotransporter family), member 3

chr10_+_77622275 0.727 ENSMUST00000174510.1
ENSMUST00000172813.1
Ube2g2

ubiquitin-conjugating enzyme E2G 2

chr17_+_29490812 0.727 ENSMUST00000024811.6
Pim1
proviral integration site 1
chr4_+_33031527 0.717 ENSMUST00000029944.6
Ube2j1
ubiquitin-conjugating enzyme E2J 1
chr7_-_118533298 0.713 ENSMUST00000098090.3
ENSMUST00000032887.3
Coq7

demethyl-Q 7

chrX_-_74373218 0.700 ENSMUST00000178691.1
ENSMUST00000114146.1
Ubl4
Slc10a3
ubiquitin-like 4
solute carrier family 10 (sodium/bile acid cotransporter family), member 3
chr19_+_6909722 0.698 ENSMUST00000116551.3
Trmt112
tRNA methyltransferase 11-2
chr5_+_125389284 0.697 ENSMUST00000100700.2
Gm10382
predicted gene 10382
chr7_-_133776681 0.693 ENSMUST00000130182.1
ENSMUST00000106139.1
Dhx32

DEAH (Asp-Glu-Ala-His) box polypeptide 32

chrX_+_153139941 0.682 ENSMUST00000039720.4
ENSMUST00000144175.2
Rragb

Ras-related GTP binding B

chr9_-_32541589 0.672 ENSMUST00000016231.7
Fli1
Friend leukemia integration 1
chr11_+_69981127 0.672 ENSMUST00000108593.1
Ctdnep1
CTD nuclear envelope phosphatase 1
chr17_-_12769605 0.672 ENSMUST00000024599.7
Igf2r
insulin-like growth factor 2 receptor
chr9_-_89705017 0.668 ENSMUST00000058488.6
Tmed3
transmembrane emp24 domain containing 3
chr3_+_89459325 0.660 ENSMUST00000107410.1
Pmvk
phosphomevalonate kinase
chr10_-_128923948 0.656 ENSMUST00000131271.1
Bloc1s1
biogenesis of lysosome-related organelles complex-1, subunit 1
chr15_-_93398263 0.655 ENSMUST00000162160.1
ENSMUST00000076070.2
Zcrb1

zinc finger CCHC-type and RNA binding motif 1

chr15_+_84923383 0.653 ENSMUST00000165443.2
Nup50
nucleoporin 50
chr10_+_77622363 0.632 ENSMUST00000172772.1
Ube2g2
ubiquitin-conjugating enzyme E2G 2
chr1_-_93445642 0.613 ENSMUST00000042498.7
Hdlbp
high density lipoprotein (HDL) binding protein
chr7_+_3704025 0.612 ENSMUST00000108623.1
ENSMUST00000139818.1
ENSMUST00000108625.1
Rps9


ribosomal protein S9


chr2_+_32775769 0.612 ENSMUST00000066352.5
Ptrh1
peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)
chr18_+_53176345 0.608 ENSMUST00000037850.5
Snx2
sorting nexin 2
chr16_+_49699198 0.606 ENSMUST00000046777.4
ENSMUST00000142682.1
Ift57

intraflagellar transport 57

chr10_-_84533884 0.582 ENSMUST00000053871.3
Ckap4
cytoskeleton-associated protein 4
chr3_+_89459118 0.576 ENSMUST00000029564.5
Pmvk
phosphomevalonate kinase
chr10_+_128322443 0.573 ENSMUST00000026446.2
Cnpy2
canopy 2 homolog (zebrafish)
chr3_+_96697100 0.570 ENSMUST00000107077.3
Pias3
protein inhibitor of activated STAT 3
chr14_-_55643523 0.570 ENSMUST00000132338.1
Tm9sf1
transmembrane 9 superfamily member 1
chr17_-_47688028 0.565 ENSMUST00000113301.1
ENSMUST00000113302.3
Tomm6

translocase of outer mitochondrial membrane 6 homolog (yeast)

chr16_-_94370994 0.558 ENSMUST00000113914.1
ENSMUST00000113905.1
Pigp

phosphatidylinositol glycan anchor biosynthesis, class P

chr5_+_124540695 0.556 ENSMUST00000060226.4
Tmed2
transmembrane emp24 domain trafficking protein 2
chr7_+_45873127 0.554 ENSMUST00000107718.1
Kdelr1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr5_+_76140271 0.548 ENSMUST00000031143.6
Srd5a3
steroid 5 alpha-reductase 3
chr10_+_4432467 0.546 ENSMUST00000095893.4
ENSMUST00000118544.1
ENSMUST00000117489.1
1700052N19Rik


RIKEN cDNA 1700052N19 gene


chr5_-_124352233 0.543 ENSMUST00000111472.1
Cdk2ap1
CDK2 (cyclin-dependent kinase 2)-associated protein 1
chr10_-_7956223 0.535 ENSMUST00000146444.1
Tab2
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr5_-_100038869 0.529 ENSMUST00000153442.1
Hnrnpdl
heterogeneous nuclear ribonucleoprotein D-like
chr15_+_6386598 0.529 ENSMUST00000080880.5
ENSMUST00000110664.2
ENSMUST00000110663.2
ENSMUST00000161812.1
ENSMUST00000160134.1
Dab2




disabled 2, mitogen-responsive phosphoprotein




chr2_+_144368961 0.515 ENSMUST00000028911.8
ENSMUST00000147747.1
ENSMUST00000183618.1
Csrp2bp

Pet117
cysteine and glycine-rich protein 2 binding protein

PET117 homolog (S. cerevisiae)
chr14_-_55643251 0.512 ENSMUST00000120041.1
ENSMUST00000121937.1
ENSMUST00000133707.1
ENSMUST00000002391.8
ENSMUST00000121791.1
Tm9sf1




transmembrane 9 superfamily member 1




chr5_-_137533297 0.508 ENSMUST00000111020.1
ENSMUST00000111023.1
Gnb2

guanine nucleotide binding protein (G protein), beta 2

chr12_+_108792946 0.506 ENSMUST00000021692.7
Yy1
YY1 transcription factor
chr14_-_55643800 0.506 ENSMUST00000122358.1
Tm9sf1
transmembrane 9 superfamily member 1
chr9_+_14784638 0.505 ENSMUST00000034405.4
Mre11a
meiotic recombination 11 homolog A (S. cerevisiae)
chr1_+_182124737 0.504 ENSMUST00000111018.1
ENSMUST00000027792.5
Srp9

signal recognition particle 9

chr10_-_128923439 0.504 ENSMUST00000153731.1
ENSMUST00000026405.3
Bloc1s1

biogenesis of lysosome-related organelles complex-1, subunit 1

chr7_-_44869788 0.501 ENSMUST00000046575.9
Ptov1
prostate tumor over expressed gene 1
chr3_+_89246397 0.501 ENSMUST00000168900.1
Krtcap2
keratinocyte associated protein 2
chr17_-_24163668 0.496 ENSMUST00000040735.5
Amdhd2
amidohydrolase domain containing 2
chr10_-_128922888 0.479 ENSMUST00000135161.1
Rdh5
retinol dehydrogenase 5
chr5_+_143403819 0.475 ENSMUST00000110731.2
Kdelr2
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr11_+_69913888 0.468 ENSMUST00000072581.2
ENSMUST00000116358.1
Gps2

G protein pathway suppressor 2

chr14_-_55643720 0.463 ENSMUST00000138085.1
Tm9sf1
transmembrane 9 superfamily member 1
chr8_-_85555261 0.462 ENSMUST00000034138.5
Dnaja2
DnaJ (Hsp40) homolog, subfamily A, member 2
chr8_+_123477859 0.461 ENSMUST00000001520.7
Afg3l1
AFG3(ATPase family gene 3)-like 1 (yeast)
chr5_+_28071356 0.445 ENSMUST00000059155.10
Insig1
insulin induced gene 1
chr7_-_45526146 0.439 ENSMUST00000167273.1
ENSMUST00000042105.8
Ppp1r15a

protein phosphatase 1, regulatory (inhibitor) subunit 15A

chr6_+_88084473 0.438 ENSMUST00000032143.6
Rpn1
ribophorin I
chr11_+_94629741 0.434 ENSMUST00000021239.6
Lrrc59
leucine rich repeat containing 59
chr14_+_26638237 0.432 ENSMUST00000112318.3
Arf4
ADP-ribosylation factor 4
chr16_-_94370647 0.426 ENSMUST00000113910.1
Pigp
phosphatidylinositol glycan anchor biosynthesis, class P
chr7_+_82867327 0.426 ENSMUST00000082237.5
Mex3b
mex3 homolog B (C. elegans)
chr14_-_31251194 0.426 ENSMUST00000022459.3
Phf7
PHD finger protein 7
chr17_-_56183887 0.422 ENSMUST00000019723.7
D17Wsu104e
DNA segment, Chr 17, Wayne State University 104, expressed
chrX_-_36864238 0.413 ENSMUST00000115249.3
ENSMUST00000115248.3
C330007P06Rik

RIKEN cDNA C330007P06 gene

chr7_+_97696634 0.410 ENSMUST00000026506.4
Clns1a
chloride channel, nucleotide-sensitive, 1A
chr1_+_75168631 0.377 ENSMUST00000162768.1
ENSMUST00000160439.1
ENSMUST00000027394.5
Zfand2b


zinc finger, AN1 type domain 2B


chr3_+_96697076 0.375 ENSMUST00000162778.2
ENSMUST00000064900.9
Pias3

protein inhibitor of activated STAT 3

chr11_+_69914179 0.372 ENSMUST00000057884.5
Gps2
G protein pathway suppressor 2
chr4_+_115737738 0.369 ENSMUST00000106525.2
Efcab14
EF-hand calcium binding domain 14
chr9_+_104063376 0.361 ENSMUST00000120854.1
Acad11
acyl-Coenzyme A dehydrogenase family, member 11
chr12_+_4082574 0.349 ENSMUST00000020986.7
Dnajc27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr14_-_62761112 0.344 ENSMUST00000053959.6
Ints6
integrator complex subunit 6
chr8_+_13757663 0.340 ENSMUST00000043962.8
Cdc16
CDC16 cell division cycle 16
chr8_+_107150621 0.335 ENSMUST00000034400.3
Cyb5b
cytochrome b5 type B
chr6_-_117907753 0.333 ENSMUST00000035534.4
4933440N22Rik
RIKEN cDNA 4933440N22 gene
chr8_+_105373265 0.331 ENSMUST00000160650.1
Plekhg4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr18_+_34331132 0.320 ENSMUST00000072576.3
ENSMUST00000119329.1
Srp19

signal recognition particle 19

chr2_+_179893909 0.291 ENSMUST00000098996.1
Gm10711
predicted gene 10711
chr4_+_130047840 0.286 ENSMUST00000044565.8
ENSMUST00000132251.1
Col16a1

collagen, type XVI, alpha 1

chr16_-_13903015 0.279 ENSMUST00000115804.2
Pdxdc1
pyridoxal-dependent decarboxylase domain containing 1
chr8_-_94601720 0.278 ENSMUST00000034226.6
Fam192a
family with sequence similarity 192, member A
chr11_+_52232183 0.277 ENSMUST00000109072.1
Skp1a
S-phase kinase-associated protein 1A
chr10_-_84533968 0.276 ENSMUST00000167671.1
Ckap4
cytoskeleton-associated protein 4
chr4_+_33031371 0.276 ENSMUST00000124992.1
Ube2j1
ubiquitin-conjugating enzyme E2J 1
chr7_-_90475971 0.275 ENSMUST00000032843.7
Tmem126b
transmembrane protein 126B
chr15_+_79892397 0.275 ENSMUST00000175714.1
ENSMUST00000109620.3
ENSMUST00000165537.1
Apobec3


apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3


chr15_+_80255184 0.275 ENSMUST00000109605.3
Atf4
activating transcription factor 4
chr12_-_87472267 0.274 ENSMUST00000021428.7
Snw1
SNW domain containing 1
chr16_+_4939099 0.267 ENSMUST00000050881.8
Nudt16l1
nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1
chr4_-_129641060 0.265 ENSMUST00000046425.9
ENSMUST00000133803.1
Txlna

taxilin alpha

chr8_+_108714644 0.263 ENSMUST00000043896.8
Zfhx3
zinc finger homeobox 3
chr8_+_106168857 0.257 ENSMUST00000034378.3
Slc7a6
solute carrier family 7 (cationic amino acid transporter, y+ system), member 6
chr13_-_100833369 0.255 ENSMUST00000067246.4
Slc30a5
solute carrier family 30 (zinc transporter), member 5
chr7_+_102210335 0.253 ENSMUST00000140631.1
ENSMUST00000120879.1
ENSMUST00000146996.1
Pgap2


post-GPI attachment to proteins 2


chr18_+_73863672 0.234 ENSMUST00000134847.1
Mro
maestro
chr15_+_79892436 0.226 ENSMUST00000175752.1
ENSMUST00000176325.1
Apobec3

apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3

chr7_-_126898249 0.225 ENSMUST00000121532.1
ENSMUST00000032926.5
Tmem219

transmembrane protein 219

chr11_-_72796028 0.224 ENSMUST00000156294.1
Cyb5d2
cytochrome b5 domain containing 2
chr14_+_26638074 0.219 ENSMUST00000022429.2
Arf4
ADP-ribosylation factor 4
chr9_-_36767595 0.213 ENSMUST00000120381.2
Stt3a
STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)
chr2_+_70661556 0.208 ENSMUST00000112201.1
ENSMUST00000028509.4
ENSMUST00000133432.1
ENSMUST00000112205.1
Gorasp2



golgi reassembly stacking protein 2



chr19_-_53038534 0.208 ENSMUST00000183274.1
ENSMUST00000182097.1
ENSMUST00000069988.8
Xpnpep1


X-prolyl aminopeptidase (aminopeptidase P) 1, soluble


chr8_+_111033890 0.207 ENSMUST00000034441.7
Aars
alanyl-tRNA synthetase
chr7_-_45459839 0.207 ENSMUST00000094434.4
Ftl1
ferritin light chain 1
chr1_+_171345684 0.203 ENSMUST00000006579.4
Pfdn2
prefoldin 2
chr2_-_132247747 0.201 ENSMUST00000110163.1
ENSMUST00000180286.1
ENSMUST00000028816.2
Tmem230


transmembrane protein 230


chr4_-_129640691 0.200 ENSMUST00000084264.5
Txlna
taxilin alpha
chr11_-_69920581 0.189 ENSMUST00000108610.1
Eif5a
eukaryotic translation initiation factor 5A
chr12_+_4082596 0.184 ENSMUST00000049584.5
Dnajc27
DnaJ (Hsp40) homolog, subfamily C, member 27

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.6 GO:0061075 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
2.0 6.1 GO:1990523 bone regeneration(GO:1990523)
1.7 6.9 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
1.0 3.1 GO:0006083 acetate metabolic process(GO:0006083)
1.0 7.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.8 2.5 GO:0070476 rRNA (guanine-N7)-methylation(GO:0070476)
0.8 2.3 GO:0051105 regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.8 2.3 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.7 3.6 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.7 3.5 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.5 1.6 GO:0045819 plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819)
0.5 2.0 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.5 1.4 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.5 2.3 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.4 1.3 GO:0050787 glycolate metabolic process(GO:0009441) enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) glycolate biosynthetic process(GO:0046295) detoxification of mercury ion(GO:0050787) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of cellular amino acid biosynthetic process(GO:2000284)
0.4 2.6 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.3 1.2 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.3 6.3 GO:0007530 sex determination(GO:0007530)
0.3 1.2 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.3 1.4 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.3 0.8 GO:0010248 B cell negative selection(GO:0002352) establishment or maintenance of transmembrane electrochemical gradient(GO:0010248) regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.3 2.4 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.3 1.0 GO:0060578 extraocular skeletal muscle development(GO:0002074) subthalamic nucleus development(GO:0021763) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.2 1.2 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.2 1.9 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.2 2.8 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.2 1.1 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.2 1.1 GO:0018158 protein oxidation(GO:0018158)
0.2 1.7 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.2 2.5 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.2 1.7 GO:1903298 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
0.2 0.5 GO:0016095 polyprenol catabolic process(GO:0016095)
0.2 0.7 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.2 0.5 GO:0045204 MAPK export from nucleus(GO:0045204)
0.2 0.5 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.2 2.0 GO:0002227 innate immune response in mucosa(GO:0002227)
0.2 0.9 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.2 1.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.2 0.6 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.2 0.6 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.2 0.9 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1 1.0 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.1 0.5 GO:0035026 leading edge cell differentiation(GO:0035026)
0.1 0.6 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.8 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.1 0.6 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.1 1.1 GO:0007135 meiosis II(GO:0007135) positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 1.0 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1 0.3 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1 0.3 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 1.2 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.1 0.5 GO:0032196 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) transposition(GO:0032196)
0.1 0.5 GO:1901072 glucosamine-containing compound catabolic process(GO:1901072)
0.1 0.7 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.1 0.7 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 0.2 GO:0043686 co-translational protein modification(GO:0043686)
0.1 0.4 GO:0072697 protein localization to cell cortex(GO:0072697)
0.1 0.8 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.1 0.2 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.9 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 2.0 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 5.2 GO:0032526 response to retinoic acid(GO:0032526)
0.1 2.0 GO:0043277 apoptotic cell clearance(GO:0043277)
0.1 0.2 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.1 0.2 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 0.3 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.1 1.2 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.1 GO:0071873 response to norepinephrine(GO:0071873)
0.0 2.0 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.4 GO:0045794 negative regulation of cell volume(GO:0045794)
0.0 2.8 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)
0.0 0.6 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.8 GO:2001273 regulation of glucose import in response to insulin stimulus(GO:2001273)
0.0 0.7 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.5 GO:0018195 peptidyl-arginine modification(GO:0018195)
0.0 0.5 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.3 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 0.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.5 GO:0042407 cristae formation(GO:0042407)
0.0 0.1 GO:0006566 threonine metabolic process(GO:0006566)
0.0 0.7 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.2 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 1.3 GO:0006414 translational elongation(GO:0006414)
0.0 0.9 GO:0048255 mRNA stabilization(GO:0048255)
0.0 0.7 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.6 GO:0072673 lamellipodium morphogenesis(GO:0072673)
0.0 0.9 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.1 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0 0.4 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.0 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.1 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.1 GO:0031424 keratinization(GO:0031424)
0.0 0.3 GO:0016180 snRNA processing(GO:0016180)
0.0 0.5 GO:0042026 protein refolding(GO:0042026)
0.0 0.2 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.5 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.3 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 1.0 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.4 GO:0018279 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.3 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.0 GO:0070625 zymogen granule exocytosis(GO:0070625)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.7 3.5 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.4 2.0 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.4 2.8 GO:0001940 male pronucleus(GO:0001940)
0.3 2.5 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.3 6.1 GO:0031527 filopodium membrane(GO:0031527)
0.2 1.7 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.2 0.7 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.2 0.6 GO:0030905 retromer, tubulation complex(GO:0030905)
0.2 1.3 GO:0097413 Lewy body(GO:0097413)
0.1 1.8 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.7 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.5 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 2.3 GO:0000800 lateral element(GO:0000800)
0.1 1.7 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.5 GO:0005745 m-AAA complex(GO:0005745)
0.1 0.6 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.4 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.1 1.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.8 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 3.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.9 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 1.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 1.0 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 2.3 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.6 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 2.0 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.9 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.9 GO:0042555 MCM complex(GO:0042555)
0.1 0.7 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.4 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.6 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 2.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.8 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.3 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.5 GO:0031011 Ino80 complex(GO:0031011)
0.0 2.4 GO:0031970 organelle envelope lumen(GO:0031970)
0.0 0.6 GO:0044292 dendrite terminus(GO:0044292)
0.0 1.8 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 1.2 GO:0016235 aggresome(GO:0016235)
0.0 1.7 GO:0005844 polysome(GO:0005844)
0.0 0.7 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.8 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 1.0 GO:0016592 mediator complex(GO:0016592)
0.0 0.2 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 2.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 2.4 GO:0030018 Z disc(GO:0030018)
0.0 0.8 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 2.7 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.9 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 15.3 GO:0005783 endoplasmic reticulum(GO:0005783)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 7.1 GO:0046923 ER retention sequence binding(GO:0046923)
1.0 3.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.7 2.0 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.6 2.3 GO:0048408 epidermal growth factor binding(GO:0048408)
0.5 1.6 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.5 2.3 GO:0000150 recombinase activity(GO:0000150)
0.4 3.5 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.4 1.3 GO:0036470 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.4 1.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.4 1.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.4 2.5 GO:0008312 7S RNA binding(GO:0008312)
0.3 1.6 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.3 6.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.3 2.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.2 0.8 GO:0004096 catalase activity(GO:0004096)
0.2 0.5 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.2 6.7 GO:0070412 R-SMAD binding(GO:0070412)
0.2 1.4 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.2 6.0 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 1.7 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.2 0.6 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.2 0.6 GO:1990460 leptin receptor binding(GO:1990460)
0.1 2.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 1.9 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.5 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.1 2.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.4 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.1 2.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 1.3 GO:0015926 glucosidase activity(GO:0015926)
0.1 0.6 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 9.1 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 0.7 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 0.8 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.8 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 1.2 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.7 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 3.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 3.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 1.1 GO:0016805 dipeptidase activity(GO:0016805)
0.1 0.2 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 0.9 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 1.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.2 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.1 2.0 GO:0005109 frizzled binding(GO:0005109)
0.1 2.3 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.1 0.6 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.7 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 1.1 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.5 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.5 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.5 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.8 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.9 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.9 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 6.1 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 2.5 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 0.9 GO:0045182 translation regulator activity(GO:0045182)
0.0 0.1 GO:0070905 serine binding(GO:0070905)
0.0 1.2 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 5.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.1 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768)
0.0 15.2 GO:0005509 calcium ion binding(GO:0005509)
0.0 1.0 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 1.2 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.0 0.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.3 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.0 0.7 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.7 GO:0020037 heme binding(GO:0020037)
0.0 0.6 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.5 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.7 GO:0004497 monooxygenase activity(GO:0004497)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 1.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.7 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.4 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 6.1 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.1 3.9 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.1 3.0 PID_BARD1_PATHWAY BARD1 signaling events
0.1 0.5 PID_IL3_PATHWAY IL3-mediated signaling events
0.1 0.9 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.1 1.4 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 1.6 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.1 0.7 PID_IL5_PATHWAY IL5-mediated signaling events
0.1 2.3 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 1.2 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.0 0.5 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 0.3 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.0 1.3 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 1.0 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.6 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.0 1.5 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 1.5 ST_FAS_SIGNALING_PATHWAY Fas Signaling Pathway
0.0 1.0 PID_PLK1_PATHWAY PLK1 signaling events
0.0 0.7 PID_MTOR_4PATHWAY mTOR signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.1 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.3 2.6 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.2 2.8 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2 3.0 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 1.9 REACTOME_N_GLYCAN_TRIMMING_IN_THE_ER_AND_CALNEXIN_CALRETICULIN_CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.1 6.7 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 1.6 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 0.5 REACTOME_ANDROGEN_BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 1.1 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.1 2.8 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 7.5 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 2.3 REACTOME_KINESINS Genes involved in Kinesins
0.1 3.6 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 0.5 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 2.4 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 1.7 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 1.2 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.1 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.5 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.0 2.0 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.3 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 2.3 REACTOME_ER_PHAGOSOME_PATHWAY Genes involved in ER-Phagosome pathway
0.0 1.3 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.6 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.7 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME_PHOSPHORYLATION_OF_THE_APC_C Genes involved in Phosphorylation of the APC/C
0.0 0.7 REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.8 REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.4 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.0 0.4 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.3 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.2 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 1.4 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events