Motif ID: Hic2

Z-value: 1.757


Transcription factors associated with Hic2:

Gene SymbolEntrez IDGene Name
Hic2 ENSMUSG00000050240.8 Hic2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hic2mm10_v2_chr16_+_17233560_17233664-0.105.5e-01Click!


Activity profile for motif Hic2.

activity profile for motif Hic2


Sorted Z-values histogram for motif Hic2

Sorted Z-values for motif Hic2



Network of associatons between targets according to the STRING database.



First level regulatory network of Hic2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_61523889 9.654 ENSMUST00000119481.1
ENSMUST00000055815.7
Lrfn5

leucine rich repeat and fibronectin type III domain containing 5

chr15_-_66831625 5.591 ENSMUST00000164163.1
Sla
src-like adaptor
chr15_+_99224976 5.487 ENSMUST00000041415.3
Kcnh3
potassium voltage-gated channel, subfamily H (eag-related), member 3
chr7_-_74554474 5.045 ENSMUST00000134539.1
ENSMUST00000026897.7
ENSMUST00000098371.2
Slco3a1


solute carrier organic anion transporter family, member 3a1


chr4_+_154960915 4.726 ENSMUST00000049621.6
Hes5
hairy and enhancer of split 5 (Drosophila)
chr13_-_54055650 4.567 ENSMUST00000021932.5
Drd1a
dopamine receptor D1A
chr11_+_78324200 4.564 ENSMUST00000102478.3
Aldoc
aldolase C, fructose-bisphosphate
chr11_+_104231573 4.252 ENSMUST00000132977.1
ENSMUST00000132245.1
ENSMUST00000100347.4
Mapt


microtubule-associated protein tau


chr2_-_71546745 4.198 ENSMUST00000024159.6
Dlx2
distal-less homeobox 2
chr11_+_104231465 4.183 ENSMUST00000145227.1
Mapt
microtubule-associated protein tau
chr2_+_70563435 4.050 ENSMUST00000123330.1
Gad1
glutamate decarboxylase 1
chr2_-_181156993 4.014 ENSMUST00000055990.7
Eef1a2
eukaryotic translation elongation factor 1 alpha 2
chr10_-_109010955 3.993 ENSMUST00000105276.1
ENSMUST00000064054.7
Syt1

synaptotagmin I

chr11_+_104231515 3.991 ENSMUST00000106993.3
Mapt
microtubule-associated protein tau
chr4_-_64046925 3.907 ENSMUST00000107377.3
Tnc
tenascin C
chr11_+_75193783 3.886 ENSMUST00000102514.3
Rtn4rl1
reticulon 4 receptor-like 1
chr11_+_104231390 3.868 ENSMUST00000106992.3
Mapt
microtubule-associated protein tau
chr2_-_163918683 3.859 ENSMUST00000044734.2
Rims4
regulating synaptic membrane exocytosis 4
chr12_+_109549157 3.832 ENSMUST00000128458.1
ENSMUST00000150851.1
Meg3

maternally expressed 3

chr2_+_180499893 3.757 ENSMUST00000029084.2
Ntsr1
neurotensin receptor 1
chr1_+_74854954 3.524 ENSMUST00000160379.2
Cdk5r2
cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chr15_+_92051153 3.504 ENSMUST00000169825.1
Cntn1
contactin 1
chr6_+_88724828 3.346 ENSMUST00000089449.2
Mgll
monoglyceride lipase
chr3_+_68584154 3.245 ENSMUST00000182997.1
Schip1
schwannomin interacting protein 1
chr5_+_140607334 3.225 ENSMUST00000031555.1
Lfng
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr2_+_70562854 3.213 ENSMUST00000130998.1
Gad1
glutamate decarboxylase 1
chrY_+_897782 3.210 ENSMUST00000055032.7
Kdm5d
lysine (K)-specific demethylase 5D
chr19_-_41206774 3.167 ENSMUST00000025986.7
ENSMUST00000169941.1
Tll2

tolloid-like 2

chr7_-_74554726 3.107 ENSMUST00000107453.1
Slco3a1
solute carrier organic anion transporter family, member 3a1
chr1_-_134234492 3.056 ENSMUST00000169927.1
Adora1
adenosine A1 receptor
chr11_-_89302545 3.043 ENSMUST00000061728.3
Nog
noggin
chr1_+_90203980 3.035 ENSMUST00000065587.4
ENSMUST00000159654.1
Ackr3

atypical chemokine receptor 3

chr11_-_81968415 3.022 ENSMUST00000066197.6
Asic2
acid-sensing (proton-gated) ion channel 2
chr15_-_83724979 3.006 ENSMUST00000171496.1
ENSMUST00000043634.5
ENSMUST00000076060.5
ENSMUST00000016907.7
Scube1



signal peptide, CUB domain, EGF-like 1



chrX_+_93286499 2.993 ENSMUST00000046565.7
ENSMUST00000113947.2
Arx

aristaless related homeobox

chr5_+_81021583 2.950 ENSMUST00000121707.1
Lphn3
latrophilin 3
chr11_+_97415527 2.929 ENSMUST00000121799.1
Arhgap23
Rho GTPase activating protein 23
chr1_-_154725920 2.867 ENSMUST00000004214.8
Cacna1e
calcium channel, voltage-dependent, R type, alpha 1E subunit
chr4_-_143299463 2.857 ENSMUST00000119654.1
Pdpn
podoplanin
chr19_+_8664005 2.809 ENSMUST00000035444.3
ENSMUST00000163785.1
Chrm1

cholinergic receptor, muscarinic 1, CNS

chr1_-_134235420 2.762 ENSMUST00000038191.6
ENSMUST00000086465.4
Adora1

adenosine A1 receptor

chr5_-_128953303 2.740 ENSMUST00000111346.1
Rimbp2
RIMS binding protein 2
chr3_+_123446913 2.642 ENSMUST00000029603.8
Prss12
protease, serine, 12 neurotrypsin (motopsin)
chr4_+_13743424 2.640 ENSMUST00000006761.3
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_+_23761749 2.588 ENSMUST00000144602.1
B3gat2
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chr7_+_122671378 2.561 ENSMUST00000182563.1
Cacng3
calcium channel, voltage-dependent, gamma subunit 3
chr4_-_143299498 2.505 ENSMUST00000030317.7
Pdpn
podoplanin
chr11_+_97450136 2.503 ENSMUST00000107601.1
Arhgap23
Rho GTPase activating protein 23
chr12_+_109544498 2.395 ENSMUST00000126289.1
Meg3
maternally expressed 3
chr2_+_118663235 2.394 ENSMUST00000099557.3
Pak6
p21 protein (Cdc42/Rac)-activated kinase 6
chr12_-_67222549 2.389 ENSMUST00000037181.8
Mdga2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr12_+_87026564 2.383 ENSMUST00000110187.1
ENSMUST00000156162.1
Tmem63c

transmembrane protein 63c

chr19_+_53677286 2.370 ENSMUST00000095969.3
ENSMUST00000164202.1
Rbm20

RNA binding motif protein 20

chr7_+_113765998 2.362 ENSMUST00000046687.9
Spon1
spondin 1, (f-spondin) extracellular matrix protein
chr7_+_29307924 2.359 ENSMUST00000108230.1
ENSMUST00000065181.5
Dpf1

D4, zinc and double PHD fingers family 1

chr6_-_115994953 2.354 ENSMUST00000015511.8
Plxnd1
plexin D1
chr16_+_45093611 2.332 ENSMUST00000099498.2
Ccdc80
coiled-coil domain containing 80
chr5_+_30588078 2.298 ENSMUST00000066295.2
Kcnk3
potassium channel, subfamily K, member 3
chr9_-_107710475 2.242 ENSMUST00000080560.3
Sema3f
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr18_-_78123324 2.231 ENSMUST00000160292.1
ENSMUST00000091813.5
Slc14a1

solute carrier family 14 (urea transporter), member 1

chr19_+_43440404 2.180 ENSMUST00000165311.1
Cnnm1
cyclin M1
chr16_-_17576206 2.079 ENSMUST00000090165.4
ENSMUST00000164623.1
Slc7a4

solute carrier family 7 (cationic amino acid transporter, y+ system), member 4

chr7_-_31126945 2.077 ENSMUST00000098548.4
Scn1b
sodium channel, voltage-gated, type I, beta
chr17_+_8340399 2.053 ENSMUST00000069742.6
Prr18
proline rich region 18
chr1_-_136260873 2.031 ENSMUST00000086395.5
Gpr25
G protein-coupled receptor 25
chr9_-_54661870 2.030 ENSMUST00000034822.5
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr19_+_10041548 2.004 ENSMUST00000115995.2
Fads3
fatty acid desaturase 3
chr6_+_88724667 1.988 ENSMUST00000163271.1
Mgll
monoglyceride lipase
chr3_+_68494208 1.985 ENSMUST00000182719.1
Schip1
schwannomin interacting protein 1
chr7_+_122671401 1.971 ENSMUST00000182095.1
Cacng3
calcium channel, voltage-dependent, gamma subunit 3
chrX_+_100730178 1.946 ENSMUST00000113744.1
Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr4_+_102570065 1.942 ENSMUST00000097950.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr2_+_156475803 1.938 ENSMUST00000029155.8
Epb4.1l1
erythrocyte protein band 4.1-like 1
chr7_-_126704736 1.920 ENSMUST00000131415.1
Coro1a
coronin, actin binding protein 1A
chr13_-_98206151 1.909 ENSMUST00000109426.1
Arhgef28
Rho guanine nucleotide exchange factor (GEF) 28
chr12_-_79007276 1.896 ENSMUST00000056660.6
ENSMUST00000174721.1
Tmem229b

transmembrane protein 229B

chr13_+_58807884 1.870 ENSMUST00000079828.5
Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chr6_+_88724462 1.865 ENSMUST00000113582.1
Mgll
monoglyceride lipase
chr11_-_43426192 1.863 ENSMUST00000101340.4
ENSMUST00000118368.1
ENSMUST00000020685.9
ENSMUST00000020687.8
Pttg1



pituitary tumor-transforming gene 1



chr1_+_134193432 1.848 ENSMUST00000038445.6
Mybph
myosin binding protein H
chr8_+_104170513 1.840 ENSMUST00000171018.1
ENSMUST00000167633.1
ENSMUST00000093245.5
ENSMUST00000164076.1
Bean1



brain expressed, associated with Nedd4, 1



chr2_+_119351222 1.836 ENSMUST00000028780.3
Chac1
ChaC, cation transport regulator 1
chr5_+_110544326 1.831 ENSMUST00000040001.7
Galnt9
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9
chr19_+_6497772 1.794 ENSMUST00000113458.1
ENSMUST00000113459.1
Nrxn2

neurexin II

chr14_-_103843685 1.745 ENSMUST00000172237.1
Ednrb
endothelin receptor type B
chr5_-_51567717 1.744 ENSMUST00000127135.1
ENSMUST00000151104.1
Ppargc1a

peroxisome proliferative activated receptor, gamma, coactivator 1 alpha

chr11_-_116654245 1.739 ENSMUST00000021166.5
Cygb
cytoglobin
chr3_-_116253467 1.719 ENSMUST00000090473.5
Gpr88
G-protein coupled receptor 88
chr5_+_75075464 1.714 ENSMUST00000160104.1
ENSMUST00000040477.3
Gsx2

GS homeobox 2

chr12_+_109545390 1.682 ENSMUST00000146701.1
Meg3
maternally expressed 3
chr5_+_81021202 1.677 ENSMUST00000117253.1
ENSMUST00000120128.1
Lphn3

latrophilin 3

chr13_+_42709482 1.673 ENSMUST00000066928.5
ENSMUST00000148891.1
Phactr1

phosphatase and actin regulator 1

chr2_-_113217051 1.673 ENSMUST00000080673.5
Ryr3
ryanodine receptor 3
chr9_+_114978507 1.671 ENSMUST00000183104.1
Osbpl10
oxysterol binding protein-like 10
chr6_-_92481343 1.663 ENSMUST00000113445.1
Prickle2
prickle homolog 2 (Drosophila)
chr11_+_104132841 1.637 ENSMUST00000093925.4
Crhr1
corticotropin releasing hormone receptor 1
chr15_+_87625214 1.618 ENSMUST00000068088.6
Fam19a5
family with sequence similarity 19, member A5
chr11_-_75796048 1.612 ENSMUST00000021209.7
Doc2b
double C2, beta
chr11_+_83409137 1.576 ENSMUST00000021022.3
Rasl10b
RAS-like, family 10, member B
chrX_-_48208870 1.568 ENSMUST00000088935.3
Zdhhc9
zinc finger, DHHC domain containing 9
chr6_+_88724489 1.559 ENSMUST00000113581.1
Mgll
monoglyceride lipase
chr1_-_56969827 1.552 ENSMUST00000176759.1
Satb2
special AT-rich sequence binding protein 2
chr4_+_152338887 1.518 ENSMUST00000005175.4
Chd5
chromodomain helicase DNA binding protein 5
chr13_-_49309217 1.511 ENSMUST00000110087.2
Fgd3
FYVE, RhoGEF and PH domain containing 3
chr6_-_84593810 1.490 ENSMUST00000077705.3
ENSMUST00000168003.2
Cyp26b1

cytochrome P450, family 26, subfamily b, polypeptide 1

chr15_-_81697256 1.489 ENSMUST00000072910.5
Chadl
chondroadherin-like
chr4_+_43384332 1.487 ENSMUST00000136360.1
Rusc2
RUN and SH3 domain containing 2
chr14_-_39472825 1.476 ENSMUST00000168810.2
ENSMUST00000173780.1
ENSMUST00000166968.2
Nrg3


neuregulin 3


chr3_+_68572245 1.475 ENSMUST00000170788.2
Schip1
schwannomin interacting protein 1
chr1_-_56978534 1.464 ENSMUST00000177282.1
Satb2
special AT-rich sequence binding protein 2
chr12_+_74288735 1.464 ENSMUST00000095617.1
1700086L19Rik
RIKEN cDNA 1700086L19 gene
chr16_+_30065333 1.460 ENSMUST00000023171.7
Hes1
hairy and enhancer of split 1 (Drosophila)
chr3_+_123267445 1.451 ENSMUST00000047923.7
Sec24d
Sec24 related gene family, member D (S. cerevisiae)
chr7_-_47132698 1.451 ENSMUST00000033142.5
Ptpn5
protein tyrosine phosphatase, non-receptor type 5
chr5_-_118244861 1.447 ENSMUST00000117177.1
ENSMUST00000133372.1
ENSMUST00000154786.1
ENSMUST00000121369.1
Rnft2



ring finger protein, transmembrane 2



chr11_-_66525964 1.439 ENSMUST00000066679.6
Shisa6
shisa homolog 6 (Xenopus laevis)
chr3_-_110142996 1.439 ENSMUST00000156177.2
Ntng1
netrin G1
chr2_+_156475844 1.437 ENSMUST00000103135.1
Epb4.1l1
erythrocyte protein band 4.1-like 1
chr1_+_75375271 1.431 ENSMUST00000087122.5
Speg
SPEG complex locus
chr13_+_55152640 1.416 ENSMUST00000005452.5
Fgfr4
fibroblast growth factor receptor 4
chr19_-_41743665 1.411 ENSMUST00000025993.3
Slit1
slit homolog 1 (Drosophila)
chrX_-_59568068 1.409 ENSMUST00000119833.1
ENSMUST00000131319.1
Fgf13

fibroblast growth factor 13

chr6_+_54429603 1.403 ENSMUST00000132855.1
ENSMUST00000126637.1
Wipf3

WAS/WASL interacting protein family, member 3

chr11_+_98836775 1.400 ENSMUST00000107479.2
Rapgefl1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr5_-_30461902 1.394 ENSMUST00000133509.1
ENSMUST00000074171.6
ENSMUST00000114747.2
ENSMUST00000144125.1
Otof



otoferlin



chr4_+_152338619 1.389 ENSMUST00000030775.5
ENSMUST00000164662.1
Chd5

chromodomain helicase DNA binding protein 5

chr6_-_29212240 1.384 ENSMUST00000160878.1
ENSMUST00000078155.5
Impdh1

inosine 5'-phosphate dehydrogenase 1

chr9_-_54661666 1.380 ENSMUST00000128624.1
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr4_+_136284658 1.379 ENSMUST00000144217.1
Zfp46
zinc finger protein 46
chr2_-_85196697 1.370 ENSMUST00000099930.2
ENSMUST00000111601.1
Lrrc55

leucine rich repeat containing 55

chr19_-_50678642 1.370 ENSMUST00000072685.6
ENSMUST00000164039.2
Sorcs1

VPS10 domain receptor protein SORCS 1

chr3_-_153725062 1.357 ENSMUST00000064460.5
St6galnac3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr12_+_58211772 1.349 ENSMUST00000110671.2
ENSMUST00000044299.2
Sstr1

somatostatin receptor 1

chr1_-_56969864 1.347 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr14_+_62555737 1.326 ENSMUST00000039064.7
Fam124a
family with sequence similarity 124, member A
chr2_+_71981184 1.322 ENSMUST00000090826.5
ENSMUST00000102698.3
Rapgef4

Rap guanine nucleotide exchange factor (GEF) 4

chr7_+_113766119 1.317 ENSMUST00000084696.4
Spon1
spondin 1, (f-spondin) extracellular matrix protein
chr12_+_95695350 1.305 ENSMUST00000110117.1
Flrt2
fibronectin leucine rich transmembrane protein 2
chr11_+_101155884 1.286 ENSMUST00000043654.9
Tubg2
tubulin, gamma 2
chr15_+_74516196 1.276 ENSMUST00000042035.9
Bai1
brain-specific angiogenesis inhibitor 1
chr1_+_167001457 1.256 ENSMUST00000126198.1
Fam78b
family with sequence similarity 78, member B
chr4_+_136284708 1.256 ENSMUST00000130223.1
Zfp46
zinc finger protein 46
chr4_-_41569502 1.255 ENSMUST00000108049.2
ENSMUST00000108052.3
ENSMUST00000108050.1
Fam219a


family with sequence similarity 219, member A


chr12_+_87026286 1.241 ENSMUST00000146292.1
Tmem63c
transmembrane protein 63c
chr2_+_91259822 1.235 ENSMUST00000138470.1
Pacsin3
protein kinase C and casein kinase substrate in neurons 3
chr1_+_171411305 1.234 ENSMUST00000161241.1
ENSMUST00000159207.1
Usf1

upstream transcription factor 1

chr11_+_83409655 1.223 ENSMUST00000175848.1
ENSMUST00000108140.3
Rasl10b

RAS-like, family 10, member B

chr19_+_41981709 1.208 ENSMUST00000026170.1
Ubtd1
ubiquitin domain containing 1
chr10_+_13501001 1.206 ENSMUST00000060212.6
ENSMUST00000121465.2
Fuca2

fucosidase, alpha-L- 2, plasma

chr1_+_171411343 1.206 ENSMUST00000160486.1
Usf1
upstream transcription factor 1
chr11_+_62575981 1.202 ENSMUST00000102643.1
Trpv2
transient receptor potential cation channel, subfamily V, member 2
chr1_-_134332928 1.196 ENSMUST00000168515.1
Ppfia4
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr7_-_126704816 1.196 ENSMUST00000032949.7
Coro1a
coronin, actin binding protein 1A
chr2_+_164960809 1.191 ENSMUST00000124372.1
Slc12a5
solute carrier family 12, member 5
chr7_-_16917184 1.189 ENSMUST00000173139.1
Calm3
calmodulin 3
chr15_+_84669565 1.184 ENSMUST00000171460.1
Prr5
proline rich 5 (renal)
chrX_-_59134421 1.177 ENSMUST00000033473.5
Fgf13
fibroblast growth factor 13
chr2_-_27142429 1.170 ENSMUST00000151224.2
Fam163b
family with sequence similarity 163, member B
chr10_+_24595434 1.162 ENSMUST00000020171.5
Ctgf
connective tissue growth factor
chr1_+_74332596 1.161 ENSMUST00000087225.5
Pnkd
paroxysmal nonkinesiogenic dyskinesia
chr7_+_110768169 1.157 ENSMUST00000170374.1
Ampd3
adenosine monophosphate deaminase 3
chr8_+_105373265 1.143 ENSMUST00000160650.1
Plekhg4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr1_+_90998722 1.118 ENSMUST00000068116.6
Lrrfip1
leucine rich repeat (in FLII) interacting protein 1
chr3_-_89245829 1.116 ENSMUST00000041022.8
Trim46
tripartite motif-containing 46
chr11_+_98741871 1.113 ENSMUST00000103139.4
Thra
thyroid hormone receptor alpha
chr17_-_24527830 1.103 ENSMUST00000176353.1
ENSMUST00000176237.1
Traf7

TNF receptor-associated factor 7

chr10_-_77902467 1.102 ENSMUST00000057608.4
Lrrc3
leucine rich repeat containing 3
chr13_+_54949388 1.098 ENSMUST00000026994.7
ENSMUST00000109994.2
Unc5a

unc-5 homolog A (C. elegans)

chr10_-_127666598 1.097 ENSMUST00000099157.3
Nab2
Ngfi-A binding protein 2
chr19_+_23758819 1.086 ENSMUST00000025830.7
Apba1
amyloid beta (A4) precursor protein binding, family A, member 1
chr8_+_23139030 1.084 ENSMUST00000121075.1
Ank1
ankyrin 1, erythroid
chr11_+_73018986 1.077 ENSMUST00000092937.6
Camkk1
calcium/calmodulin-dependent protein kinase kinase 1, alpha
chr14_+_57524734 1.059 ENSMUST00000089494.4
Il17d
interleukin 17D
chr3_-_57575907 1.057 ENSMUST00000120977.1
Wwtr1
WW domain containing transcription regulator 1
chr2_+_32629467 1.057 ENSMUST00000068271.4
Ak1
adenylate kinase 1
chr3_+_55242526 1.049 ENSMUST00000054237.7
ENSMUST00000167204.1
Dclk1

doublecortin-like kinase 1

chr3_-_57575760 1.048 ENSMUST00000029380.7
Wwtr1
WW domain containing transcription regulator 1
chr4_+_136143497 1.044 ENSMUST00000008016.2
Id3
inhibitor of DNA binding 3
chr4_+_62583568 1.039 ENSMUST00000098031.3
Rgs3
regulator of G-protein signaling 3
chr11_+_98741805 1.038 ENSMUST00000064187.5
Thra
thyroid hormone receptor alpha
chr3_-_88459047 1.030 ENSMUST00000165898.1
ENSMUST00000127436.1
Sema4a

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A

chr4_+_129058133 1.027 ENSMUST00000030584.4
ENSMUST00000168461.1
ENSMUST00000152565.1
Rnf19b


ring finger protein 19B


chr9_+_104569671 1.024 ENSMUST00000057742.8
Cpne4
copine IV
chr13_-_14523178 1.024 ENSMUST00000110516.2
Hecw1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr13_-_54611332 1.021 ENSMUST00000091609.4
Cltb
clathrin, light polypeptide (Lcb)
chr8_-_122551316 1.015 ENSMUST00000067252.7
Piezo1
piezo-type mechanosensitive ion channel component 1
chr7_+_91090697 1.014 ENSMUST00000107196.2
Dlg2
discs, large homolog 2 (Drosophila)
chr16_+_90831113 1.006 ENSMUST00000037539.7
ENSMUST00000099543.3
Eva1c

eva-1 homolog C (C. elegans)

chr14_+_27622433 0.999 ENSMUST00000090302.5
Erc2
ELKS/RAB6-interacting/CAST family member 2
chr11_-_97744659 0.993 ENSMUST00000018691.8
Pip4k2b
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chr13_+_20090538 0.989 ENSMUST00000072519.5
Elmo1
engulfment and cell motility 1
chr2_-_172043466 0.988 ENSMUST00000087950.3
Cbln4
cerebellin 4 precursor protein
chr18_-_46728342 0.973 ENSMUST00000035804.7
Cdo1
cysteine dioxygenase 1, cytosolic
chr5_-_129787175 0.965 ENSMUST00000031399.6
Psph
phosphoserine phosphatase
chr3_-_88458876 0.954 ENSMUST00000147200.1
ENSMUST00000169222.1
Sema4a

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A

chrX_-_133688978 0.950 ENSMUST00000149154.1
ENSMUST00000167944.1
Pcdh19

protocadherin 19

chr4_-_123116686 0.948 ENSMUST00000166337.1
Gm17244
predicted gene, 17244
chr13_-_54611274 0.945 ENSMUST00000049575.7
Cltb
clathrin, light polypeptide (Lcb)
chr1_-_21961581 0.945 ENSMUST00000029667.6
ENSMUST00000173058.1
ENSMUST00000173404.1
Kcnq5


potassium voltage-gated channel, subfamily Q, member 5


chr11_-_98022594 0.940 ENSMUST00000103144.3
ENSMUST00000017552.6
ENSMUST00000092736.4
ENSMUST00000107562.1
Cacnb1



calcium channel, voltage-dependent, beta 1 subunit




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.8 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
1.8 16.3 GO:1900034 regulation of cellular response to heat(GO:1900034)
1.5 6.2 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
1.4 4.2 GO:0061075 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
1.3 8.8 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
1.2 3.6 GO:0021759 globus pallidus development(GO:0021759)
1.1 3.2 GO:0007386 compartment pattern specification(GO:0007386)
1.1 5.4 GO:1901731 positive regulation of platelet aggregation(GO:1901731)
1.0 7.3 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
1.0 3.9 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.9 3.8 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.9 2.8 GO:0050915 sensory perception of sour taste(GO:0050915)
0.9 5.6 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.9 3.5 GO:0021586 pons maturation(GO:0021586)
0.8 3.2 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.7 2.2 GO:0071918 urea transmembrane transport(GO:0071918)
0.7 3.0 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.7 2.2 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.7 4.0 GO:0032796 uropod organization(GO:0032796)
0.6 3.2 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.6 8.3 GO:0015732 prostaglandin transport(GO:0015732)
0.6 1.7 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.6 2.8 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.6 1.7 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.6 1.7 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.5 1.6 GO:0035934 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.5 2.1 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.5 1.5 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.5 1.5 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.5 1.5 GO:0060596 mammary placode formation(GO:0060596)
0.5 2.4 GO:0019086 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) late viral transcription(GO:0019086)
0.5 1.4 GO:0061144 alveolar secondary septum development(GO:0061144)
0.5 1.9 GO:0003360 brainstem development(GO:0003360)
0.5 0.5 GO:0071926 endocannabinoid signaling pathway(GO:0071926)
0.5 4.6 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.4 3.6 GO:0005513 detection of calcium ion(GO:0005513)
0.4 1.7 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.4 1.7 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.4 2.9 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.4 0.8 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.4 1.6 GO:0061743 motor learning(GO:0061743)
0.4 2.2 GO:0097491 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.4 2.6 GO:0098909 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.4 1.8 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.4 1.8 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.4 0.4 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.4 6.7 GO:0001553 luteinization(GO:0001553)
0.4 1.4 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.3 1.0 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.3 1.3 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.3 0.6 GO:0032274 gonadotropin secretion(GO:0032274)
0.3 1.6 GO:0015671 oxygen transport(GO:0015671)
0.3 2.2 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.3 0.9 GO:1990705 cholangiocyte proliferation(GO:1990705)
0.3 0.3 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923)
0.3 2.1 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.3 0.9 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.3 1.5 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.3 0.9 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.3 1.2 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.3 1.5 GO:2001025 positive regulation of response to drug(GO:2001025)
0.3 7.7 GO:0008340 determination of adult lifespan(GO:0008340)
0.3 0.8 GO:0032275 luteinizing hormone secretion(GO:0032275) positive regulation of gonadotropin secretion(GO:0032278)
0.3 1.9 GO:0090527 actin filament reorganization(GO:0090527)
0.3 0.8 GO:0051542 elastin biosynthetic process(GO:0051542)
0.3 1.4 GO:0006177 GMP biosynthetic process(GO:0006177)
0.3 1.1 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.3 4.4 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.3 4.4 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.3 3.9 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.3 1.3 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.3 0.8 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.2 1.7 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.2 0.7 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.2 1.0 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.2 1.0 GO:0006751 glutathione catabolic process(GO:0006751)
0.2 0.9 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.2 1.6 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.2 1.3 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.2 1.3 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.2 0.9 GO:0050913 sensory perception of bitter taste(GO:0050913)
0.2 1.9 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.2 1.2 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.2 0.8 GO:0072061 inner medullary collecting duct development(GO:0072061)
0.2 1.0 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.2 1.8 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.2 1.0 GO:0033762 taurine metabolic process(GO:0019530) response to glucagon(GO:0033762)
0.2 0.8 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.2 0.6 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.2 4.9 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.2 3.6 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.2 0.9 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.2 0.5 GO:0015886 heme transport(GO:0015886)
0.2 1.1 GO:0046103 ADP biosynthetic process(GO:0006172) inosine biosynthetic process(GO:0046103)
0.2 0.9 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.2 0.2 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.2 0.5 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.2 5.5 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.2 0.9 GO:0070166 enamel mineralization(GO:0070166)
0.2 0.2 GO:0046544 development of secondary male sexual characteristics(GO:0046544)
0.2 0.8 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.2 1.0 GO:0061450 trophoblast cell migration(GO:0061450) regulation of trophoblast cell migration(GO:1901163)
0.2 0.3 GO:0001757 somite specification(GO:0001757)
0.2 0.7 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.2 0.7 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.2 0.5 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.2 0.5 GO:0030321 transepithelial chloride transport(GO:0030321)
0.2 0.6 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.2 0.3 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.2 0.6 GO:0015744 succinate transport(GO:0015744)
0.2 0.9 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.2 3.5 GO:0090218 positive regulation of lipid kinase activity(GO:0090218)
0.2 0.5 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.2 0.5 GO:0006597 spermine biosynthetic process(GO:0006597)
0.2 0.6 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.2 1.2 GO:0016139 glycoside catabolic process(GO:0016139)
0.2 0.5 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 0.3 GO:1904672 regulation of somatic stem cell population maintenance(GO:1904672)
0.1 1.9 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 1.9 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 0.4 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.1 0.4 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1 1.6 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.4 GO:0051866 general adaptation syndrome(GO:0051866)
0.1 0.4 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1 0.4 GO:0051295 establishment of meiotic spindle localization(GO:0051295) formin-nucleated actin cable assembly(GO:0070649)
0.1 0.4 GO:0070459 prolactin secretion(GO:0070459)
0.1 1.5 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.1 1.9 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.1 1.7 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.1 0.6 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.1 1.4 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 1.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.4 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 0.3 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1 0.7 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 1.6 GO:0042297 vocal learning(GO:0042297) imitative learning(GO:0098596)
0.1 0.5 GO:2000277 positive regulation of oxidative phosphorylation uncoupler activity(GO:2000277)
0.1 1.2 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.8 GO:0046645 positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645) positive regulation of uterine smooth muscle contraction(GO:0070474)
0.1 0.5 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.1 1.0 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.1 0.4 GO:0035523 protein K29-linked deubiquitination(GO:0035523) protein K6-linked deubiquitination(GO:0044313)
0.1 0.2 GO:0001828 inner cell mass cell differentiation(GO:0001826) inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.1 0.8 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.6 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.8 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.1 0.7 GO:0031424 keratinization(GO:0031424)
0.1 0.3 GO:0009826 unidimensional cell growth(GO:0009826)
0.1 0.8 GO:0060426 lung vasculature development(GO:0060426)
0.1 0.7 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 0.3 GO:0002922 positive regulation of humoral immune response(GO:0002922)
0.1 0.3 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.1 2.8 GO:0097320 membrane tubulation(GO:0097320)
0.1 0.2 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1 2.2 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.1 0.5 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 0.3 GO:0006106 fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
0.1 0.6 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.1 0.3 GO:0045004 DNA replication proofreading(GO:0045004)
0.1 4.1 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.1 0.4 GO:1903898 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.1 0.7 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.1 0.3 GO:1902915 negative regulation of protein import into nucleus, translocation(GO:0033159) negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.1 0.9 GO:0006449 regulation of translational termination(GO:0006449)
0.1 0.5 GO:0097167 circadian regulation of translation(GO:0097167)
0.1 3.3 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 0.8 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.5 GO:0009202 deoxyribonucleoside triphosphate biosynthetic process(GO:0009202)
0.1 0.6 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 0.7 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1 0.2 GO:1905203 regulation of connective tissue replacement(GO:1905203)
0.1 0.3 GO:0042126 nitrate metabolic process(GO:0042126)
0.1 0.7 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 3.0 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 0.8 GO:0001574 ganglioside biosynthetic process(GO:0001574) lipid glycosylation(GO:0030259)
0.1 0.2 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.1 0.3 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) cellular response to caffeine(GO:0071313)
0.1 1.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.7 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.3 GO:0019405 alditol catabolic process(GO:0019405) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 1.0 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 1.3 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.1 0.2 GO:0070970 interleukin-2 secretion(GO:0070970)
0.1 1.7 GO:1900452 regulation of long term synaptic depression(GO:1900452)
0.1 0.2 GO:0042196 dichloromethane metabolic process(GO:0018900) chlorinated hydrocarbon metabolic process(GO:0042196) halogenated hydrocarbon metabolic process(GO:0042197)
0.1 1.4 GO:0016082 synaptic vesicle priming(GO:0016082)
0.1 0.2 GO:0042182 ketone catabolic process(GO:0042182) ketone body catabolic process(GO:0046952)
0.1 0.2 GO:1905072 detection of oxygen(GO:0003032) cell migration involved in endocardial cushion formation(GO:0003273) positive regulation of vascular smooth muscle cell differentiation(GO:1905065) cardiac jelly development(GO:1905072)
0.1 1.0 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 0.2 GO:0009814 defense response, incompatible interaction(GO:0009814)
0.1 0.3 GO:0042360 vitamin E metabolic process(GO:0042360)
0.1 0.5 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.1 0.8 GO:1990173 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.1 0.2 GO:0009414 response to water deprivation(GO:0009414)
0.1 1.9 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.1 0.5 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.1 0.1 GO:0071442 regulation of histone H3-K14 acetylation(GO:0071440) positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1 3.3 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 0.2 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.1 2.2 GO:0007020 microtubule nucleation(GO:0007020)
0.1 2.8 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.1 1.0 GO:0072643 interferon-gamma secretion(GO:0072643)
0.1 0.4 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.1 1.0 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 1.9 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.1 1.1 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.1 0.3 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 0.7 GO:0061470 interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619)
0.1 1.1 GO:0099612 protein localization to axon(GO:0099612)
0.1 0.3 GO:0032298 positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
0.1 0.2 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 0.2 GO:1990523 bone regeneration(GO:1990523)
0.1 0.9 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 0.1 GO:0042662 negative regulation of mesodermal cell fate specification(GO:0042662) regulation of cardiac cell fate specification(GO:2000043)
0.1 0.3 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.6 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.1 0.1 GO:0033864 positive regulation of NAD(P)H oxidase activity(GO:0033864)
0.1 1.3 GO:0019835 cytolysis(GO:0019835)
0.1 0.3 GO:0019236 response to pheromone(GO:0019236)
0.1 1.1 GO:0006677 glycosylceramide metabolic process(GO:0006677)
0.1 0.1 GO:2000812 response to rapamycin(GO:1901355) regulation of barbed-end actin filament capping(GO:2000812)
0.1 0.1 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.2 GO:0032532 regulation of microvillus length(GO:0032532)
0.1 3.4 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 0.3 GO:0033034 positive regulation of neutrophil apoptotic process(GO:0033031) positive regulation of myeloid cell apoptotic process(GO:0033034)
0.1 0.2 GO:1903772 regulation of viral budding via host ESCRT complex(GO:1903772)
0.1 0.2 GO:0046104 thymidine metabolic process(GO:0046104)
0.1 1.0 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 0.6 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 0.2 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.1 0.2 GO:0009644 response to high light intensity(GO:0009644)
0.1 0.4 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 1.0 GO:0018345 protein palmitoylation(GO:0018345)
0.1 0.4 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.1 1.8 GO:0016601 Rac protein signal transduction(GO:0016601)
0.1 0.3 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 0.3 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.1 0.2 GO:0044805 late nucleophagy(GO:0044805)
0.1 0.3 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.1 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.1 1.1 GO:0033198 response to ATP(GO:0033198)
0.1 0.3 GO:0097501 stress response to metal ion(GO:0097501)
0.1 0.4 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.2 GO:0071544 diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.1 1.2 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.1 0.3 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.1 0.8 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.5 GO:0044065 regulation of respiratory system process(GO:0044065)
0.1 2.0 GO:0048821 erythrocyte development(GO:0048821)
0.0 0.1 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.0 1.1 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.6 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 2.3 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.0 0.4 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.1 GO:0072708 response to sorbitol(GO:0072708)
0.0 0.1 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.0 0.7 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.2 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.2 GO:0035470 positive regulation of vascular wound healing(GO:0035470)
0.0 3.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.5 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.6 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.7 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 1.4 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.5 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.6 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.5 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.2 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.2 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.4 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.6 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.9 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.5 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.7 GO:0001990 regulation of systemic arterial blood pressure by hormone(GO:0001990)
0.0 0.2 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.6 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.0 0.1 GO:0051030 snRNA transport(GO:0051030)
0.0 0.3 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.0 0.9 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0 0.1 GO:0044036 cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.0 0.3 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.3 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.1 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.0 0.6 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
0.0 0.5 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.5 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.1 GO:0006550 isoleucine metabolic process(GO:0006549) isoleucine catabolic process(GO:0006550)
0.0 0.3 GO:0048193 Golgi vesicle transport(GO:0048193)
0.0 0.2 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.1 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.0 GO:0060956 stem cell fate commitment(GO:0048865) stem cell fate specification(GO:0048866) endocardial cell differentiation(GO:0060956)
0.0 0.5 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.3 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.7 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.1 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.4 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.3 GO:0006023 aminoglycan biosynthetic process(GO:0006023) glycosaminoglycan biosynthetic process(GO:0006024)
0.0 0.2 GO:1903056 melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.0 0.4 GO:0015813 L-glutamate transport(GO:0015813)
0.0 0.2 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.9 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.0 0.3 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 1.9 GO:0031638 zymogen activation(GO:0031638)
0.0 1.8 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.2 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.6 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 0.3 GO:0048820 hair follicle maturation(GO:0048820)
0.0 0.2 GO:0030812 negative regulation of nucleotide catabolic process(GO:0030812) negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
0.0 0.2 GO:1902416 positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.0 0.1 GO:0002677 negative regulation of chronic inflammatory response(GO:0002677)
0.0 0.7 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.6 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.3 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.1 GO:0035584 calcium-mediated signaling using intracellular calcium source(GO:0035584)
0.0 0.3 GO:0034508 centromere complex assembly(GO:0034508)
0.0 0.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.0 GO:0033566 gamma-tubulin complex localization(GO:0033566)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0015817 histidine transport(GO:0015817)
0.0 0.5 GO:0019884 antigen processing and presentation of exogenous antigen(GO:0019884)
0.0 0.4 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.8 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.1 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.0 0.3 GO:0000054 ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753)
0.0 0.2 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.1 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.0 1.1 GO:0009408 response to heat(GO:0009408)
0.0 0.1 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598) epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.0 0.5 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.3 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.0 1.6 GO:0021549 cerebellum development(GO:0021549)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.0 0.0 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.4 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.5 GO:0035690 cellular response to drug(GO:0035690)
0.0 0.0 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.3 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.7 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.5 GO:0043297 apical junction assembly(GO:0043297)
0.0 0.2 GO:0045727 positive regulation of translation(GO:0045727)
0.0 0.1 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.1 GO:0015867 ATP transport(GO:0015867)
0.0 0.3 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.4 GO:0090102 cochlea development(GO:0090102)
0.0 0.3 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.4 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.3 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.0 0.2 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.7 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.3 GO:0035640 exploration behavior(GO:0035640)
0.0 0.2 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.0 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.2 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.1 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 16.3 GO:0045298 tubulin complex(GO:0045298)
1.2 3.5 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.9 3.8 GO:0032280 symmetric synapse(GO:0032280)
0.7 4.0 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.6 1.9 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.6 9.2 GO:0043196 varicosity(GO:0043196)
0.5 7.4 GO:0005614 interstitial matrix(GO:0005614)
0.4 1.3 GO:0044316 cone cell pedicle(GO:0044316)
0.4 8.6 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.4 5.5 GO:0071437 invadopodium(GO:0071437)
0.4 4.1 GO:0032426 stereocilium tip(GO:0032426)
0.3 1.0 GO:0044194 cytolytic granule(GO:0044194)
0.3 1.3 GO:1990032 parallel fiber(GO:1990032)
0.3 0.6 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.3 14.5 GO:0048786 presynaptic active zone(GO:0048786)
0.3 1.1 GO:1990769 proximal neuron projection(GO:1990769)
0.3 0.3 GO:0097454 Schwann cell microvillus(GO:0097454)
0.2 3.7 GO:0031045 dense core granule(GO:0031045)
0.2 0.7 GO:0098835 presynaptic endosome(GO:0098830) presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.2 2.6 GO:0043083 synaptic cleft(GO:0043083)
0.2 1.3 GO:0005859 muscle myosin complex(GO:0005859)
0.2 2.0 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.2 0.7 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 2.4 GO:0016589 NURF complex(GO:0016589)
0.2 7.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 6.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.2 0.7 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.2 1.5 GO:0043194 axon initial segment(GO:0043194)
0.2 1.0 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.2 0.8 GO:0032437 cuticular plate(GO:0032437)
0.2 0.5 GO:0048179 activin receptor complex(GO:0048179)
0.1 4.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 1.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 3.2 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 1.7 GO:0044294 dendritic growth cone(GO:0044294)
0.1 1.7 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.1 0.4 GO:0034457 Mpp10 complex(GO:0034457)
0.1 1.1 GO:0001520 outer dense fiber(GO:0001520)
0.1 1.6 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 1.0 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 0.9 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.3 GO:1990812 growth cone filopodium(GO:1990812)
0.1 0.6 GO:1990131 Iml1 complex(GO:1990130) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 2.1 GO:0033268 node of Ranvier(GO:0033268)
0.1 0.5 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.4 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 1.3 GO:0031931 TORC1 complex(GO:0031931)
0.1 0.5 GO:0008091 spectrin(GO:0008091)
0.1 0.4 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 1.2 GO:0032584 growth cone membrane(GO:0032584)
0.1 2.0 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.4 GO:0097487 vesicle lumen(GO:0031983) multivesicular body, internal vesicle(GO:0097487)
0.1 1.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 0.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 0.5 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 1.2 GO:0038201 TOR complex(GO:0038201)
0.1 0.9 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.1 1.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.2 GO:0097225 sperm midpiece(GO:0097225)
0.1 0.6 GO:0070852 cell body fiber(GO:0070852)
0.1 0.5 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 2.0 GO:0000242 pericentriolar material(GO:0000242)
0.1 0.4 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1 0.8 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 0.5 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 1.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 1.5 GO:0005771 multivesicular body(GO:0005771)
0.1 0.4 GO:0097361 CIA complex(GO:0097361)
0.1 0.4 GO:0033263 CORVET complex(GO:0033263)
0.1 5.6 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 0.3 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.1 0.5 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 0.6 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.8 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.1 GO:0000125 PCAF complex(GO:0000125)
0.1 0.4 GO:0071439 clathrin complex(GO:0071439)
0.1 0.8 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.4 GO:0005638 lamin filament(GO:0005638)
0.1 0.3 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 2.8 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.1 0.8 GO:0001673 male germ cell nucleus(GO:0001673)
0.1 1.5 GO:0030137 COPI-coated vesicle(GO:0030137)
0.1 0.9 GO:0000145 exocyst(GO:0000145)
0.1 0.4 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1 1.4 GO:0071565 nBAF complex(GO:0071565)
0.1 1.3 GO:0005682 U5 snRNP(GO:0005682)
0.1 0.5 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 2.5 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 7.2 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 0.6 GO:0070938 contractile ring(GO:0070938)
0.1 0.9 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.5 GO:0042588 zymogen granule(GO:0042588)
0.0 1.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.5 GO:0005642 annulate lamellae(GO:0005642)
0.0 1.5 GO:0097440 apical dendrite(GO:0097440)
0.0 1.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.8 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.8 GO:0031201 SNARE complex(GO:0031201)
0.0 0.2 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.8 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.5 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 0.5 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.8 GO:0035371 microtubule plus-end(GO:0035371)
0.0 3.0 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 3.3 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.5 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.5 GO:0042555 MCM complex(GO:0042555)
0.0 0.4 GO:0045180 basal cortex(GO:0045180)
0.0 2.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.1 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.5 GO:0000124 SAGA complex(GO:0000124)
0.0 1.3 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 0.2 GO:0034709 methylosome(GO:0034709)
0.0 1.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 4.2 GO:0044309 neuron spine(GO:0044309)
0.0 0.9 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.6 GO:0030118 clathrin coat(GO:0030118)
0.0 0.1 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.5 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.3 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 1.1 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0005838 proteasome regulatory particle(GO:0005838) proteasome accessory complex(GO:0022624)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.7 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 1.4 GO:0005844 polysome(GO:0005844)
0.0 0.1 GO:0005796 Golgi lumen(GO:0005796)
0.0 1.0 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.6 GO:0032589 neuron projection membrane(GO:0032589)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 1.5 GO:0043025 neuronal cell body(GO:0043025)
0.0 1.8 GO:0005884 actin filament(GO:0005884)
0.0 0.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.8 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.1 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.1 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 1.3 GO:0030027 lamellipodium(GO:0030027)
0.0 0.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.5 GO:0005776 autophagosome(GO:0005776)
0.0 1.6 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.4 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.5 GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network(GO:0042175)
0.0 0.2 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 16.2 GO:0099609 microtubule lateral binding(GO:0099609)
1.2 8.2 GO:0015198 oligopeptide transporter activity(GO:0015198)
1.1 3.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
1.0 7.3 GO:0004351 glutamate decarboxylase activity(GO:0004351)
1.0 3.0 GO:0016494 C-X-C chemokine receptor activity(GO:0016494) C-X-C chemokine binding(GO:0019958)
1.0 4.0 GO:0030348 syntaxin-3 binding(GO:0030348)
0.9 5.6 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.8 5.8 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609) heterotrimeric G-protein binding(GO:0032795)
0.8 2.4 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.8 4.6 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.7 2.9 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.7 2.2 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.7 8.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.7 3.9 GO:0045545 syndecan binding(GO:0045545)
0.6 5.4 GO:0019956 chemokine binding(GO:0019956)
0.6 2.8 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.6 1.7 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.5 1.6 GO:0004962 endothelin receptor activity(GO:0004962)
0.5 3.3 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.5 3.2 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.4 1.3 GO:0004994 somatostatin receptor activity(GO:0004994)
0.4 2.2 GO:0015265 urea channel activity(GO:0015265)
0.4 1.7 GO:0004096 catalase activity(GO:0004096)
0.4 3.9 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.4 1.7 GO:0001639 PLC activating G-protein coupled glutamate receptor activity(GO:0001639) G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.4 1.2 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.4 1.9 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.4 4.0 GO:0032036 myosin heavy chain binding(GO:0032036)
0.4 3.6 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.4 3.9 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.3 1.4 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.3 1.0 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.3 1.0 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.3 4.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.3 5.0 GO:0045499 chemorepellent activity(GO:0045499)
0.3 2.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.3 1.9 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.3 2.4 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.3 0.9 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.3 3.0 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.3 1.2 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.3 1.4 GO:0048495 Roundabout binding(GO:0048495)
0.3 0.8 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.3 2.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 0.7 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.2 0.7 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.2 0.7 GO:0019002 GMP binding(GO:0019002)
0.2 0.9 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.2 2.7 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.2 0.9 GO:0070976 calcium-independent protein kinase C activity(GO:0004699) TIR domain binding(GO:0070976)
0.2 5.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.2 0.6 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.2 2.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.2 4.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 0.6 GO:0030519 snoRNP binding(GO:0030519)
0.2 1.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.2 1.0 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.2 6.6 GO:0022839 ion gated channel activity(GO:0022839)
0.2 3.2 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.2 1.3 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.2 0.7 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.2 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.2 0.7 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 0.5 GO:0015232 heme transporter activity(GO:0015232)
0.2 1.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.2 0.8 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.2 0.3 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.2 0.5 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.2 1.8 GO:0005246 calcium channel regulator activity(GO:0005246)
0.2 1.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 0.3 GO:0004046 aminoacylase activity(GO:0004046)
0.2 0.5 GO:0072541 peroxynitrite reductase activity(GO:0072541)
0.2 0.9 GO:0033691 sialic acid binding(GO:0033691)
0.2 0.5 GO:0046997 sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.2 1.4 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.2 3.5 GO:0001968 fibronectin binding(GO:0001968)
0.2 5.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2 0.6 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.7 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 0.4 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 4.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.4 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.1 0.9 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.1 0.8 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.5 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.1 1.7 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.9 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.5 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 0.1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 2.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.8 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.1 0.5 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.7 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 1.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 0.8 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.4 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.9 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 1.5 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.5 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 0.6 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.1 0.3 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.1 0.5 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1 0.7 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1 0.3 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.1 1.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 0.2 GO:0004127 cytidylate kinase activity(GO:0004127)
0.1 0.7 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.3 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 0.3 GO:0004998 transferrin receptor activity(GO:0004998)
0.1 0.5 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 1.1 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 3.0 GO:0001653 peptide receptor activity(GO:0001653)
0.1 0.9 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 2.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 1.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.5 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.2 GO:0019120 hydrolase activity, acting on acid halide bonds(GO:0016824) hydrolase activity, acting on acid halide bonds, in C-halide compounds(GO:0019120) alkylhalidase activity(GO:0047651)
0.1 1.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.8 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.1 0.3 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.1 1.0 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 0.3 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.1 0.3 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.1 0.7 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 0.5 GO:0015197 peptide transporter activity(GO:0015197)
0.1 0.4 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 1.8 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 1.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 2.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 2.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 0.3 GO:0043546 molybdenum ion binding(GO:0030151) molybdopterin cofactor binding(GO:0043546)
0.1 0.2 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 0.3 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 1.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 2.7 GO:0030552 cAMP binding(GO:0030552)
0.1 0.3 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 0.5 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 0.5 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.3 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 0.2 GO:0008410 CoA-transferase activity(GO:0008410)
0.1 1.0 GO:0017166 vinculin binding(GO:0017166)
0.1 0.3 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 0.7 GO:0031996 thioesterase binding(GO:0031996)
0.1 1.5 GO:0008432 JUN kinase binding(GO:0008432)
0.1 0.2 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.1 0.6 GO:0044213 intronic transcription regulatory region DNA binding(GO:0044213)
0.1 0.2 GO:0036470 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.1 0.3 GO:0030332 cyclin binding(GO:0030332)
0.1 0.5 GO:0032564 dATP binding(GO:0032564)
0.1 0.8 GO:0070628 proteasome binding(GO:0070628)
0.1 0.5 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.3 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.8 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.5 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 1.8 GO:0030295 protein kinase activator activity(GO:0030295)
0.0 0.2 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.0 1.2 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 1.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.3 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 3.3 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 3.6 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.6 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.2 GO:0036122 BMP binding(GO:0036122)
0.0 1.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.5 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.0 0.2 GO:0016595 glutamate binding(GO:0016595)
0.0 0.9 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 4.1 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 1.5 GO:0035254 glutamate receptor binding(GO:0035254)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.5 GO:0031489 myosin V binding(GO:0031489)
0.0 0.6 GO:0005112 Notch binding(GO:0005112)
0.0 0.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0016501 prostacyclin receptor activity(GO:0016501)
0.0 0.5 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.4 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.3 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 2.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.4 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 4.3 GO:0003924 GTPase activity(GO:0003924)
0.0 0.3 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.4 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.3 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.2 GO:1990715 mRNA CDS binding(GO:1990715)
0.0 0.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 1.2 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 1.0 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.3 GO:0004407 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.0 0.1 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0070330 aromatase activity(GO:0070330)
0.0 0.5 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.8 GO:0005518 collagen binding(GO:0005518)
0.0 0.4 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.6 GO:0009055 electron carrier activity(GO:0009055)
0.0 0.6 GO:0019955 cytokine binding(GO:0019955)
0.0 0.1 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.2 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.5 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.0 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.0 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0042979 ornithine decarboxylase regulator activity(GO:0042979)
0.0 1.3 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 0.1 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.8 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.6 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 16.3 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 3.1 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.2 0.2 PID_REELIN_PATHWAY Reelin signaling pathway
0.1 4.8 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.1 1.4 PID_FGF_PATHWAY FGF signaling pathway
0.1 2.9 PID_ARF_3PATHWAY Arf1 pathway
0.1 5.1 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.1 3.5 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 3.2 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 0.7 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.1 3.0 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 0.8 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 3.1 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 2.1 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.1 5.2 PID_CDC42_PATHWAY CDC42 signaling events
0.1 0.9 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.1 2.1 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.1 1.6 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.1 6.8 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.1 1.4 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 1.5 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.1 4.6 PID_NOTCH_PATHWAY Notch signaling pathway
0.1 1.0 PID_IL3_PATHWAY IL3-mediated signaling events
0.0 1.5 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.7 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.1 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.0 1.8 PID_BMP_PATHWAY BMP receptor signaling
0.0 1.6 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.3 PID_EPO_PATHWAY EPO signaling pathway
0.0 0.7 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.0 0.6 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 1.1 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.5 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.4 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 0.2 PID_BARD1_PATHWAY BARD1 signaling events
0.0 0.3 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 0.4 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.0 0.6 PID_ATM_PATHWAY ATM pathway
0.0 0.5 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 0.3 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.9 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.2 PID_ERBB4_PATHWAY ErbB4 signaling events
0.0 0.6 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 0.5 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.9 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 0.2 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 7.5 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.7 15.8 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.5 11.2 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.5 6.3 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.3 7.7 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.3 2.3 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.3 1.4 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.2 2.8 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.2 4.0 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.2 4.8 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.2 2.8 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.2 2.7 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 2.5 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.1 4.8 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 5.1 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 3.8 REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 5.3 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.1 1.0 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.1 3.6 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.1 1.1 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.4 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 2.0 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.1 1.4 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.0 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 7.6 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 3.6 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 1.1 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 1.6 REACTOME_GRB2_EVENTS_IN_ERBB2_SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.1 1.4 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 1.5 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 2.1 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.1 1.2 REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.1 0.5 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 2.0 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.1 0.6 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 0.5 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 4.3 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 2.3 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS Genes involved in Trafficking of AMPA receptors
0.1 0.9 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 2.0 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 0.7 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 1.4 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 4.4 REACTOME_SIGNALING_BY_NOTCH1 Genes involved in Signaling by NOTCH1
0.1 1.9 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 3.3 REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH Genes involved in NCAM signaling for neurite out-growth
0.1 0.2 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 3.2 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 0.7 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.0 0.7 REACTOME_INWARDLY_RECTIFYING_K_CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 1.1 REACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS Genes involved in Post NMDA receptor activation events
0.0 0.5 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.3 REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.6 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.1 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.5 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 2.2 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.3 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 1.0 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.8 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.3 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.7 REACTOME_CIRCADIAN_CLOCK Genes involved in Circadian Clock
0.0 0.5 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.0 0.3 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.9 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 1.0 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.5 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.0 0.1 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.6 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.3 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.1 REACTOME_REGULATION_OF_SIGNALING_BY_CBL Genes involved in Regulation of signaling by CBL
0.0 1.9 REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_MITOTIC_PROTEINS Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0 0.7 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.6 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.7 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.3 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.7 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.0 0.4 REACTOME_THE_ROLE_OF_NEF_IN_HIV1_REPLICATION_AND_DISEASE_PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.7 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.8 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.3 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.0 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.4 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.3 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.9 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.5 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import