Motif ID: Prdm1

Z-value: 1.302


Transcription factors associated with Prdm1:

Gene SymbolEntrez IDGene Name
Prdm1 ENSMUSG00000038151.6 Prdm1



Activity profile for motif Prdm1.

activity profile for motif Prdm1


Sorted Z-values histogram for motif Prdm1

Sorted Z-values for motif Prdm1



Network of associatons between targets according to the STRING database.



First level regulatory network of Prdm1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_137796350 8.358 ENSMUST00000030551.4
Alpl
alkaline phosphatase, liver/bone/kidney
chr9_-_107668967 7.859 ENSMUST00000177567.1
Slc38a3
solute carrier family 38, member 3
chr3_+_145758674 7.782 ENSMUST00000029845.8
Ddah1
dimethylarginine dimethylaminohydrolase 1
chr4_-_154636831 7.614 ENSMUST00000030902.6
ENSMUST00000105637.1
ENSMUST00000070313.7
ENSMUST00000105636.1
ENSMUST00000105638.2
ENSMUST00000097759.2
ENSMUST00000124771.1
Prdm16






PR domain containing 16






chr9_+_38718263 6.561 ENSMUST00000001544.5
ENSMUST00000118144.1
Vwa5a

von Willebrand factor A domain containing 5A

chr15_+_32920723 6.057 ENSMUST00000022871.5
Sdc2
syndecan 2
chr19_+_36409719 6.029 ENSMUST00000062389.5
Pcgf5
polycomb group ring finger 5
chr5_+_3343893 5.981 ENSMUST00000165117.1
Cdk6
cyclin-dependent kinase 6
chr3_-_107760221 5.495 ENSMUST00000153114.1
ENSMUST00000118593.1
ENSMUST00000120243.1
Csf1


colony stimulating factor 1 (macrophage)


chr4_-_96591555 5.435 ENSMUST00000055693.8
Cyp2j9
cytochrome P450, family 2, subfamily j, polypeptide 9
chr2_-_105399286 5.434 ENSMUST00000006128.6
Rcn1
reticulocalbin 1
chr8_-_84800024 5.376 ENSMUST00000126806.1
ENSMUST00000076715.6
Nfix

nuclear factor I/X

chr1_-_156674290 5.213 ENSMUST00000079625.4
Tor3a
torsin family 3, member A
chr11_-_77894096 4.855 ENSMUST00000017597.4
Pipox
pipecolic acid oxidase
chr8_-_84800344 4.662 ENSMUST00000099070.3
Nfix
nuclear factor I/X
chr11_-_82991829 4.261 ENSMUST00000092840.4
ENSMUST00000038211.5
Slfn9

schlafen 9

chr18_-_41951187 3.984 ENSMUST00000070949.4
Prelid2
PRELI domain containing 2
chr2_+_116067213 3.961 ENSMUST00000152412.1
G630016G05Rik
RIKEN cDNA G630016G05 gene
chr1_-_56978534 3.770 ENSMUST00000177282.1
Satb2
special AT-rich sequence binding protein 2
chr12_+_83987854 3.405 ENSMUST00000021649.7
Acot2
acyl-CoA thioesterase 2
chr7_-_142576492 3.251 ENSMUST00000140716.1
H19
H19 fetal liver mRNA
chr7_-_102250086 3.098 ENSMUST00000106923.1
ENSMUST00000098230.4
Rhog

ras homolog gene family, member G

chr13_+_74639866 3.040 ENSMUST00000169114.1
Erap1
endoplasmic reticulum aminopeptidase 1
chr5_+_147188678 2.990 ENSMUST00000065382.5
Gsx1
GS homeobox 1
chr1_+_184034381 2.979 ENSMUST00000048655.7
Dusp10
dual specificity phosphatase 10
chr7_+_45017953 2.967 ENSMUST00000044111.7
Rras
Harvey rat sarcoma oncogene, subgroup R
chr2_+_27886416 2.908 ENSMUST00000028280.7
Col5a1
collagen, type V, alpha 1
chr13_-_23430826 2.671 ENSMUST00000153753.1
ENSMUST00000141543.1
C230035I16Rik

RIKEN cDNA C230035I16 gene

chr2_-_132253227 2.667 ENSMUST00000028817.6
Pcna
proliferating cell nuclear antigen
chr2_-_80447625 2.658 ENSMUST00000028389.3
Frzb
frizzled-related protein
chr6_+_117168535 2.611 ENSMUST00000112866.1
ENSMUST00000112871.1
ENSMUST00000073043.4
Cxcl12


chemokine (C-X-C motif) ligand 12


chr11_-_82991137 2.576 ENSMUST00000138797.1
Slfn9
schlafen 9
chr2_-_51972990 2.562 ENSMUST00000145481.1
ENSMUST00000112705.2
Nmi

N-myc (and STAT) interactor

chr10_+_4710119 2.485 ENSMUST00000105588.1
ENSMUST00000105589.1
Esr1

estrogen receptor 1 (alpha)

chr3_-_101604580 2.442 ENSMUST00000036493.6
Atp1a1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr1_+_180942452 2.397 ENSMUST00000027800.8
Tmem63a
transmembrane protein 63a
chr2_-_51934943 2.365 ENSMUST00000102767.1
ENSMUST00000102768.1
Rbm43

RNA binding motif protein 43

chr16_+_35938972 2.327 ENSMUST00000023622.6
ENSMUST00000114877.1
Parp9

poly (ADP-ribose) polymerase family, member 9

chr4_+_48049080 2.277 ENSMUST00000153369.1
Nr4a3
nuclear receptor subfamily 4, group A, member 3
chrX_+_75096039 2.261 ENSMUST00000131155.1
ENSMUST00000132000.1
Dkc1

dyskeratosis congenita 1, dyskerin

chr10_-_80320506 2.238 ENSMUST00000020341.8
2310011J03Rik
RIKEN cDNA 2310011J03 gene
chr1_-_184033998 2.201 ENSMUST00000050306.5
1700056E22Rik
RIKEN cDNA 1700056E22 gene
chr8_+_66697404 2.142 ENSMUST00000039303.5
Npy1r
neuropeptide Y receptor Y1
chr14_-_26066961 2.126 ENSMUST00000100818.5
Tmem254c
transmembrane protein 254c
chr8_+_46739745 2.125 ENSMUST00000034041.7
Irf2
interferon regulatory factor 2
chr4_+_117835387 2.123 ENSMUST00000169885.1
Slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr14_+_14012491 2.109 ENSMUST00000022257.2
Atxn7
ataxin 7
chrX_+_75095854 2.109 ENSMUST00000033776.8
Dkc1
dyskeratosis congenita 1, dyskerin
chr16_-_24393588 2.068 ENSMUST00000181640.1
1110054M08Rik
RIKEN cDNA 1110054M08 gene
chr2_-_51973219 2.063 ENSMUST00000028314.2
Nmi
N-myc (and STAT) interactor
chr14_-_25927250 2.028 ENSMUST00000100811.5
Tmem254a
transmembrane protein 254a
chr2_-_116067391 1.982 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chrX_-_142966709 1.962 ENSMUST00000041317.2
Ammecr1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr14_+_65805832 1.960 ENSMUST00000022612.3
Pbk
PDZ binding kinase
chr2_-_167188787 1.855 ENSMUST00000059826.8
Kcnb1
potassium voltage gated channel, Shab-related subfamily, member 1
chr3_+_81932601 1.817 ENSMUST00000029649.2
Ctso
cathepsin O
chr1_-_32547293 1.807 ENSMUST00000171322.1
Gm5415
predicted gene 5415
chr5_-_5694024 1.798 ENSMUST00000115425.2
ENSMUST00000115427.1
ENSMUST00000115424.2
ENSMUST00000015797.4
Steap2



six transmembrane epithelial antigen of prostate 2



chr1_+_171113918 1.792 ENSMUST00000129651.1
ENSMUST00000151340.1
1700009P17Rik

RIKEN cDNA 1700009P17 gene

chr2_-_106003549 1.790 ENSMUST00000102555.4
Dnajc24
DnaJ (Hsp40) homolog, subfamily C, member 24
chr1_-_71103146 1.782 ENSMUST00000027393.7
Bard1
BRCA1 associated RING domain 1
chr2_+_14388316 1.640 ENSMUST00000114731.1
ENSMUST00000082290.7
Slc39a12

solute carrier family 39 (zinc transporter), member 12

chr5_+_30921825 1.609 ENSMUST00000117435.1
Khk
ketohexokinase
chr11_-_87108656 1.575 ENSMUST00000051395.8
Prr11
proline rich 11
chr14_+_65806066 1.558 ENSMUST00000139644.1
Pbk
PDZ binding kinase
chr5_+_30921867 1.552 ENSMUST00000123885.1
Khk
ketohexokinase
chr8_-_53638945 1.542 ENSMUST00000047768.4
Neil3
nei like 3 (E. coli)
chr5_-_138170992 1.534 ENSMUST00000139983.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr10_+_78069351 1.521 ENSMUST00000105393.1
Icosl
icos ligand
chr7_-_19118357 1.513 ENSMUST00000141380.1
Gm4969
predicted gene 4969
chr6_-_39118211 1.482 ENSMUST00000038398.6
Parp12
poly (ADP-ribose) polymerase family, member 12
chr14_+_56575603 1.440 ENSMUST00000161553.1
Parp4
poly (ADP-ribose) polymerase family, member 4
chr4_-_117182623 1.420 ENSMUST00000065896.2
Kif2c
kinesin family member 2C
chr11_+_3514861 1.410 ENSMUST00000094469.4
Selm
selenoprotein M
chr10_-_75797728 1.335 ENSMUST00000139724.1
Gstt1
glutathione S-transferase, theta 1
chr4_+_150236816 1.329 ENSMUST00000080926.6
Eno1
enolase 1, alpha non-neuron
chr16_+_43364145 1.317 ENSMUST00000148775.1
Zbtb20
zinc finger and BTB domain containing 20
chr3_-_150073620 1.302 ENSMUST00000057740.5
Rpsa-ps10
ribosomal protein SA, pseudogene 10
chr4_+_150236685 1.299 ENSMUST00000150175.1
Eno1
enolase 1, alpha non-neuron
chr5_-_115119277 1.293 ENSMUST00000031524.7
Acads
acyl-Coenzyme A dehydrogenase, short chain
chr2_+_31572775 1.286 ENSMUST00000137889.1
Fubp3
far upstream element (FUSE) binding protein 3
chr2_+_31572701 1.279 ENSMUST00000055244.6
Fubp3
far upstream element (FUSE) binding protein 3
chr2_+_14604252 1.252 ENSMUST00000114723.2
Cacnb2
calcium channel, voltage-dependent, beta 2 subunit
chr17_-_25785533 1.228 ENSMUST00000140738.1
ENSMUST00000145053.1
ENSMUST00000138759.1
ENSMUST00000133071.1
ENSMUST00000077938.3
Haghl




hydroxyacylglutathione hydrolase-like




chr7_-_130573118 1.226 ENSMUST00000159694.1
Nsmce4a
non-SMC element 4 homolog A (S. cerevisiae)
chr11_-_53707269 1.206 ENSMUST00000124352.1
ENSMUST00000020649.7
Rad50

RAD50 homolog (S. cerevisiae)

chr1_-_79671966 1.190 ENSMUST00000162342.1
Ap1s3
adaptor-related protein complex AP-1, sigma 3
chr16_+_43363855 1.183 ENSMUST00000156367.1
Zbtb20
zinc finger and BTB domain containing 20
chr10_-_75797528 1.173 ENSMUST00000120177.1
Gstt1
glutathione S-transferase, theta 1
chr2_+_31572651 1.152 ENSMUST00000113482.1
Fubp3
far upstream element (FUSE) binding protein 3
chr1_-_93801840 1.136 ENSMUST00000112890.2
ENSMUST00000027503.7
Dtymk

deoxythymidylate kinase

chr11_+_121702393 1.135 ENSMUST00000036742.7
Metrnl
meteorin, glial cell differentiation regulator-like
chr7_+_128265675 1.133 ENSMUST00000118169.1
ENSMUST00000142841.1
Slc5a2

solute carrier family 5 (sodium/glucose cotransporter), member 2

chr10_-_22149270 1.128 ENSMUST00000179054.1
ENSMUST00000069372.6
E030030I06Rik

RIKEN cDNA E030030I06 gene

chrX_-_74023908 1.127 ENSMUST00000033769.8
ENSMUST00000114352.1
ENSMUST00000068286.5
ENSMUST00000114360.3
ENSMUST00000114354.3
Irak1




interleukin-1 receptor-associated kinase 1




chrX_+_73411096 1.123 ENSMUST00000033740.5
Zfp92
zinc finger protein 92
chr16_+_65520503 1.114 ENSMUST00000176330.1
ENSMUST00000004964.8
ENSMUST00000176038.1
Pou1f1


POU domain, class 1, transcription factor 1


chr15_+_85510812 1.091 ENSMUST00000079690.2
Gm4825
predicted pseudogene 4825
chr6_+_4003926 1.085 ENSMUST00000031670.8
Gng11
guanine nucleotide binding protein (G protein), gamma 11
chr15_-_89379246 1.035 ENSMUST00000049968.7
Odf3b
outer dense fiber of sperm tails 3B
chr16_-_38713235 1.008 ENSMUST00000023487.4
Arhgap31
Rho GTPase activating protein 31
chr1_-_191183244 0.995 ENSMUST00000027941.8
Atf3
activating transcription factor 3
chr5_+_30921556 0.994 ENSMUST00000031053.8
Khk
ketohexokinase
chr8_-_45410539 0.974 ENSMUST00000034056.4
ENSMUST00000167106.1
Tlr3

toll-like receptor 3

chr11_+_87853207 0.970 ENSMUST00000038196.6
Mks1
Meckel syndrome, type 1
chr3_-_94412883 0.961 ENSMUST00000181305.1
1700040D17Rik
RIKEN cDNA 1700040D17 gene
chr2_+_167062934 0.942 ENSMUST00000125674.1
1500012F01Rik
RIKEN cDNA 1500012F01 gene
chr4_+_154170730 0.932 ENSMUST00000030897.8
Megf6
multiple EGF-like-domains 6
chr7_-_102565425 0.907 ENSMUST00000106913.1
ENSMUST00000033264.4
Trim21

tripartite motif-containing 21

chr13_-_21810190 0.902 ENSMUST00000110469.1
ENSMUST00000091749.2
Hist1h2bq

histone cluster 1, H2bq

chr13_+_34162953 0.875 ENSMUST00000124996.1
ENSMUST00000147632.1
Psmg4

proteasome (prosome, macropain) assembly chaperone 4

chrX_-_134111852 0.862 ENSMUST00000033610.6
Nox1
NADPH oxidase 1
chr2_-_91070180 0.858 ENSMUST00000153367.1
ENSMUST00000079976.3
Slc39a13

solute carrier family 39 (metal ion transporter), member 13

chr3_-_9833653 0.856 ENSMUST00000161949.1
Pag1
phosphoprotein associated with glycosphingolipid microdomains 1
chr19_-_5875268 0.845 ENSMUST00000025728.6
Frmd8
FERM domain containing 8
chr2_-_175131864 0.843 ENSMUST00000108929.2
Gm14399
predicted gene 14399
chr19_+_55894508 0.837 ENSMUST00000142291.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr1_+_74544345 0.836 ENSMUST00000027362.7
Plcd4
phospholipase C, delta 4
chr7_-_4684963 0.836 ENSMUST00000079970.4
Hspbp1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr3_-_95411176 0.803 ENSMUST00000177599.1
Gm5070
predicted gene 5070
chr11_+_70562980 0.783 ENSMUST00000079244.5
ENSMUST00000102558.4
Mink1

misshapen-like kinase 1 (zebrafish)

chr10_+_81574699 0.772 ENSMUST00000131794.1
ENSMUST00000136341.1
Tle2

transducin-like enhancer of split 2, homolog of Drosophila E(spl)

chr8_-_94434259 0.767 ENSMUST00000180445.1
9330175E14Rik
RIKEN cDNA 9330175E14 gene
chr13_-_3918157 0.762 ENSMUST00000091853.4
Net1
neuroepithelial cell transforming gene 1
chr1_+_72307413 0.754 ENSMUST00000027379.8
Xrcc5
X-ray repair complementing defective repair in Chinese hamster cells 5
chr1_+_42851233 0.748 ENSMUST00000057208.9
Mrps9
mitochondrial ribosomal protein S9
chr17_+_94873986 0.746 ENSMUST00000108007.4
Gm20939
predicted gene, 20939
chr16_+_24393350 0.745 ENSMUST00000038053.6
Lpp
LIM domain containing preferred translocation partner in lipoma
chr2_-_26640230 0.743 ENSMUST00000181621.1
ENSMUST00000180659.1
Snhg7

small nucleolar RNA host gene (non-protein coding) 7

chr6_+_127233756 0.742 ENSMUST00000071458.3
Gm4968
predicted gene 4968
chr13_+_108670576 0.736 ENSMUST00000074680.6
Rps3a3
ribosomal protein S3A3
chr7_+_12922290 0.701 ENSMUST00000108539.1
ENSMUST00000004554.7
ENSMUST00000147435.1
ENSMUST00000137329.1
Rps5



ribosomal protein S5



chr1_+_61638819 0.698 ENSMUST00000138768.1
ENSMUST00000075374.3
Pard3b

par-3 partitioning defective 3 homolog B (C. elegans)

chr3_+_68584154 0.668 ENSMUST00000182997.1
Schip1
schwannomin interacting protein 1
chr1_+_181150926 0.664 ENSMUST00000134115.1
ENSMUST00000111059.1
Cnih4

cornichon homolog 4 (Drosophila)

chr17_+_46681038 0.662 ENSMUST00000002845.6
Mea1
male enhanced antigen 1
chrX_+_166344692 0.658 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
Gpm6b





glycoprotein m6b





chr7_+_30121915 0.650 ENSMUST00000098596.3
ENSMUST00000153792.1
Zfp382

zinc finger protein 382

chr7_-_45136231 0.647 ENSMUST00000124300.1
ENSMUST00000085377.5
Rpl13a
Flt3l
ribosomal protein L13A
FMS-like tyrosine kinase 3 ligand
chr1_-_184845838 0.636 ENSMUST00000068725.3
Marc2
mitochondrial amidoxime reducing component 2
chr15_+_5143861 0.625 ENSMUST00000051186.8
Prkaa1
protein kinase, AMP-activated, alpha 1 catalytic subunit
chr7_+_131371138 0.605 ENSMUST00000075610.6
Pstk
phosphoseryl-tRNA kinase
chr3_-_9833617 0.596 ENSMUST00000108384.2
Pag1
phosphoprotein associated with glycosphingolipid microdomains 1
chr7_+_30184160 0.585 ENSMUST00000098594.2
Cox7a1
cytochrome c oxidase subunit VIIa 1
chr11_+_102881204 0.583 ENSMUST00000021307.3
ENSMUST00000159834.1
Ccdc103

coiled-coil domain containing 103

chr2_-_91070283 0.575 ENSMUST00000111436.2
ENSMUST00000073575.5
Slc39a13

solute carrier family 39 (metal ion transporter), member 13

chr11_-_102469839 0.565 ENSMUST00000103086.3
Itga2b
integrin alpha 2b
chr11_+_3330781 0.560 ENSMUST00000136536.1
ENSMUST00000093399.4
Pik3ip1

phosphoinositide-3-kinase interacting protein 1

chr3_+_24333046 0.559 ENSMUST00000077389.6
Gm7536
predicted gene 7536
chr2_-_119477613 0.557 ENSMUST00000110808.1
ENSMUST00000049920.7
Ino80

INO80 homolog (S. cerevisiae)

chr7_-_64392214 0.554 ENSMUST00000032735.5
Mphosph10
M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
chr10_+_80602865 0.550 ENSMUST00000038411.4
ENSMUST00000079883.4
Adat3
Scamp4
adenosine deaminase, tRNA-specific 3
secretory carrier membrane protein 4
chr17_+_33919332 0.540 ENSMUST00000025161.7
Tapbp
TAP binding protein
chr6_-_34977999 0.540 ENSMUST00000044387.7
2010107G12Rik
RIKEN cDNA 2010107G12 gene
chr13_-_18031616 0.535 ENSMUST00000099736.2
Vdac3-ps1
voltage-dependent anion channel 3, pseudogene 1
chr14_+_55672235 0.499 ENSMUST00000002397.5
Gmpr2
guanosine monophosphate reductase 2
chr8_-_84662841 0.494 ENSMUST00000060427.4
Ier2
immediate early response 2
chr7_-_5413145 0.492 ENSMUST00000108569.2
Vmn1r58
vomeronasal 1 receptor 58
chr1_-_171234290 0.492 ENSMUST00000079957.6
Fcer1g
Fc receptor, IgE, high affinity I, gamma polypeptide
chr13_-_92483996 0.488 ENSMUST00000040106.7
Fam151b
family with sequence similarity 151, member B
chr4_+_141115660 0.481 ENSMUST00000181450.1
4921514A10Rik
RIKEN cDNA 4921514A10 gene
chr2_+_180499893 0.478 ENSMUST00000029084.2
Ntsr1
neurotensin receptor 1
chr2_-_24919572 0.478 ENSMUST00000046227.5
ENSMUST00000114432.2
ENSMUST00000091348.4
ENSMUST00000150379.1
ENSMUST00000152161.1
ENSMUST00000102938.3
Ehmt1





euchromatic histone methyltransferase 1





chr17_-_24455265 0.458 ENSMUST00000056032.7
E4f1
E4F transcription factor 1
chr2_-_90904827 0.453 ENSMUST00000005647.3
Ndufs3
NADH dehydrogenase (ubiquinone) Fe-S protein 3
chr10_+_80603253 0.440 ENSMUST00000180350.1
Scamp4
secretory carrier membrane protein 4
chr10_+_39133981 0.428 ENSMUST00000019991.7
Tube1
epsilon-tubulin 1
chr10_-_81496329 0.428 ENSMUST00000020463.7
Ncln
nicalin homolog (zebrafish)
chr5_+_135168283 0.405 ENSMUST00000031692.5
Bcl7b
B cell CLL/lymphoma 7B
chr1_+_132008285 0.398 ENSMUST00000146432.1
Elk4
ELK4, member of ETS oncogene family
chr11_+_119267887 0.398 ENSMUST00000106259.2
Gaa
glucosidase, alpha, acid
chr17_-_46680870 0.396 ENSMUST00000165007.1
ENSMUST00000071841.5
Klhdc3

kelch domain containing 3

chr4_+_24973419 0.395 ENSMUST00000038920.1
Gpr63
G protein-coupled receptor 63
chr9_+_98296556 0.384 ENSMUST00000035031.6
ENSMUST00000112935.1
Nmnat3

nicotinamide nucleotide adenylyltransferase 3

chr16_-_50432340 0.381 ENSMUST00000066037.6
ENSMUST00000089399.4
ENSMUST00000089404.3
ENSMUST00000114477.1
ENSMUST00000138166.1
Bbx




bobby sox homolog (Drosophila)




chr16_-_76403673 0.372 ENSMUST00000052867.7
Gm9843
predicted gene 9843
chr14_-_45477856 0.370 ENSMUST00000141424.1
Fermt2
fermitin family homolog 2 (Drosophila)
chr2_+_32535724 0.368 ENSMUST00000133366.1
Fam102a
family with sequence similarity 102, member A
chr10_+_116301374 0.364 ENSMUST00000092167.5
Ptprb
protein tyrosine phosphatase, receptor type, B
chr1_-_121567906 0.361 ENSMUST00000001724.5
Ddx18
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr6_+_71373400 0.359 ENSMUST00000066747.7
ENSMUST00000172321.1
Cd8a

CD8 antigen, alpha chain

chr17_+_24895116 0.353 ENSMUST00000043907.7
Mrps34
mitochondrial ribosomal protein S34
chr16_+_38562821 0.352 ENSMUST00000163948.1
Tmem39a
transmembrane protein 39a
chr14_-_16249154 0.346 ENSMUST00000148121.1
ENSMUST00000112624.1
Oxsm

3-oxoacyl-ACP synthase, mitochondrial

chr16_-_91044473 0.338 ENSMUST00000118522.1
Paxbp1
PAX3 and PAX7 binding protein 1
chr6_+_5725639 0.337 ENSMUST00000115556.1
ENSMUST00000115555.1
ENSMUST00000115559.3
Dync1i1


dynein cytoplasmic 1 intermediate chain 1


chr17_-_33824346 0.336 ENSMUST00000173879.1
ENSMUST00000166693.2
ENSMUST00000173019.1
ENSMUST00000087342.6
ENSMUST00000173844.1
Rps28




ribosomal protein S28




chr8_-_70527945 0.333 ENSMUST00000138260.1
ENSMUST00000117580.1
Kxd1

KxDL motif containing 1

chr13_+_21833736 0.333 ENSMUST00000180288.1
ENSMUST00000110467.1
Hist1h2br

histone cluster 1 H2br

chr14_+_63860290 0.324 ENSMUST00000022528.4
Pinx1
PIN2/TERF1 interacting, telomerase inhibitor 1
chr10_-_81496313 0.318 ENSMUST00000118498.1
Ncln
nicalin homolog (zebrafish)
chr18_-_66022580 0.307 ENSMUST00000143990.1
Lman1
lectin, mannose-binding, 1
chr1_-_78196832 0.298 ENSMUST00000004994.9
Pax3
paired box gene 3
chr15_+_76899908 0.289 ENSMUST00000068407.5
ENSMUST00000109793.2
Commd5

COMM domain containing 5

chr10_+_128322443 0.284 ENSMUST00000026446.2
Cnpy2
canopy 2 homolog (zebrafish)
chr8_-_66486494 0.282 ENSMUST00000026681.5
Tma16
translation machinery associated 16 homolog (S. cerevisiae)
chr17_-_35895920 0.273 ENSMUST00000059740.8
2310061I04Rik
RIKEN cDNA 2310061I04 gene
chr14_-_20480106 0.270 ENSMUST00000065504.9
ENSMUST00000100844.4
Anxa7

annexin A7

chr5_+_109940426 0.269 ENSMUST00000170826.1
Gm15446
predicted gene 15446
chr9_+_96895617 0.269 ENSMUST00000071781.6
Gm10123
predicted pseudogene 10123

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.6 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
1.8 5.4 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
1.6 4.9 GO:0006553 lysine metabolic process(GO:0006553)
1.6 7.9 GO:0015817 glutamine transport(GO:0006868) histidine transport(GO:0015817) cellular response to potassium ion starvation(GO:0051365)
1.4 4.2 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
1.1 8.7 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
1.0 2.9 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.9 2.8 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.9 2.7 GO:0070366 regulation of hepatocyte differentiation(GO:0070366)
0.9 4.4 GO:0090669 snoRNA guided rRNA pseudouridine synthesis(GO:0000454) telomerase RNA stabilization(GO:0090669)
0.9 6.0 GO:0044838 cell quiescence(GO:0044838)
0.8 2.5 GO:0042196 dichloromethane metabolic process(GO:0018900) chlorinated hydrocarbon metabolic process(GO:0042196) halogenated hydrocarbon metabolic process(GO:0042197)
0.7 3.0 GO:0090335 regulation of brown fat cell differentiation(GO:0090335)
0.7 2.1 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.7 7.8 GO:0006527 arginine catabolic process(GO:0006527)
0.7 2.7 GO:1902990 leading strand elongation(GO:0006272) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.7 2.6 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.6 2.5 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.6 2.4 GO:1903416 response to glycoside(GO:1903416)
0.6 10.0 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.6 1.1 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.5 1.5 GO:0042097 interleukin-4 biosynthetic process(GO:0042097) regulation of interleukin-4 biosynthetic process(GO:0045402)
0.5 3.0 GO:0021984 adenohypophysis development(GO:0021984)
0.4 1.3 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.4 1.1 GO:0046077 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.4 3.4 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.4 0.8 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.4 1.9 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.4 1.8 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.4 2.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.3 3.6 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.3 0.6 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.3 1.2 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.3 3.3 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.3 1.4 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.3 2.3 GO:0060330 regulation of response to interferon-gamma(GO:0060330)
0.2 1.0 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.2 3.8 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.2 0.9 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.2 1.1 GO:1904659 glucose transmembrane transport(GO:1904659)
0.2 1.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.2 0.6 GO:0090289 regulation of osteoclast proliferation(GO:0090289)
0.2 0.9 GO:0072592 regulation of integrin biosynthetic process(GO:0045113) oxygen metabolic process(GO:0072592)
0.2 8.4 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.2 2.1 GO:0030432 peristalsis(GO:0030432)
0.2 1.8 GO:0046826 negative regulation of protein export from nucleus(GO:0046826) protein K6-linked ubiquitination(GO:0085020)
0.2 1.6 GO:0046459 short-chain fatty acid metabolic process(GO:0046459)
0.2 0.5 GO:0043181 vacuolar sequestering(GO:0043181)
0.2 3.1 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.2 1.5 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 1.8 GO:0016926 protein desumoylation(GO:0016926)
0.1 0.7 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.5 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.1 1.2 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 1.0 GO:0061009 common bile duct development(GO:0061009)
0.1 0.5 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.1 3.1 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.1 0.3 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.1 0.8 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 0.8 GO:0043383 negative T cell selection(GO:0043383) negative thymic T cell selection(GO:0045060)
0.1 0.4 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1 0.6 GO:0060594 mammary gland specification(GO:0060594)
0.1 0.5 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.1 0.6 GO:0042126 nitrate metabolic process(GO:0042126)
0.1 0.6 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.6 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 0.6 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.1 0.7 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 3.7 GO:0015914 phospholipid transport(GO:0015914)
0.1 3.5 GO:0070303 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.1 2.5 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.5 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.3 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.1 0.6 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1 0.2 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.1 0.4 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.0 0.2 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 1.9 GO:0060325 face morphogenesis(GO:0060325)
0.0 2.1 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 0.8 GO:0051451 myoblast migration(GO:0051451)
0.0 0.7 GO:0043248 proteasome assembly(GO:0043248)
0.0 5.4 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.0 0.4 GO:0070932 histone H3 deacetylation(GO:0070932)
0.0 0.8 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.2 GO:0035878 nail development(GO:0035878)
0.0 1.6 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.3 GO:0014842 skeletal muscle satellite cell proliferation(GO:0014841) regulation of skeletal muscle satellite cell proliferation(GO:0014842) skeletal muscle cell proliferation(GO:0014856) regulation of skeletal muscle cell proliferation(GO:0014857)
0.0 0.3 GO:2001022 positive regulation of response to DNA damage stimulus(GO:2001022)
0.0 1.5 GO:0006289 nucleotide-excision repair(GO:0006289)
0.0 0.2 GO:0071380 cellular response to prostaglandin stimulus(GO:0071379) cellular response to prostaglandin E stimulus(GO:0071380)
0.0 0.1 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.0 0.7 GO:0031648 protein destabilization(GO:0031648)
0.0 1.0 GO:0051972 regulation of telomerase activity(GO:0051972)
0.0 0.2 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.3 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 2.6 GO:0051099 positive regulation of binding(GO:0051099)
0.0 0.1 GO:0061470 interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619)
0.0 1.6 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.9 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.2 GO:0046519 sphingoid metabolic process(GO:0046519)
0.0 0.2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.5 GO:0007606 sensory perception of chemical stimulus(GO:0007606)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.5 GO:1990682 CSF1-CSF1R complex(GO:1990682)
1.1 4.4 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
1.0 2.9 GO:0005588 collagen type V trimer(GO:0005588)
0.9 2.7 GO:0070557 PCNA-p21 complex(GO:0070557)
0.4 6.6 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.4 2.5 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.3 2.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.3 1.8 GO:0070531 BRCA1-A complex(GO:0070531)
0.3 2.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.3 0.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.2 0.9 GO:0071438 invadopodium membrane(GO:0071438)
0.2 1.2 GO:0030870 Mre11 complex(GO:0030870)
0.2 0.8 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.2 0.6 GO:0034457 Mpp10 complex(GO:0034457)
0.2 1.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.2 8.3 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.2 7.7 GO:0016235 aggresome(GO:0016235)
0.1 1.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.5 GO:0032280 symmetric synapse(GO:0032280)
0.1 0.3 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
0.1 1.5 GO:0042555 MCM complex(GO:0042555)
0.1 0.8 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 5.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 0.6 GO:0097452 GAIT complex(GO:0097452)
0.1 0.3 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 6.0 GO:0031519 PcG protein complex(GO:0031519)
0.1 0.5 GO:0042824 MHC class I peptide loading complex(GO:0042824) TAP complex(GO:0042825)
0.1 0.3 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.1 4.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 1.0 GO:0036038 MKS complex(GO:0036038)
0.1 1.8 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 0.2 GO:0005940 septin ring(GO:0005940)
0.0 0.8 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 1.9 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 3.3 GO:0005844 polysome(GO:0005844)
0.0 0.6 GO:0031011 Ino80 complex(GO:0031011)
0.0 3.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 1.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 1.1 GO:0031526 brush border membrane(GO:0031526)
0.0 0.6 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 1.0 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 5.2 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 6.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.2 GO:0001939 female pronucleus(GO:0001939)
0.0 10.8 GO:0005925 focal adhesion(GO:0005925)
0.0 0.3 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 1.2 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.1 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.1 GO:0034715 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
0.0 1.0 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 0.8 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 2.4 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.5 GO:1990204 oxidoreductase complex(GO:1990204)
0.0 0.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 2.1 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.3 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.9 GO:0015182 L-asparagine transmembrane transporter activity(GO:0015182)
2.1 8.4 GO:0004035 alkaline phosphatase activity(GO:0004035)
2.0 6.0 GO:0098770 FBXO family protein binding(GO:0098770)
1.4 4.2 GO:0004454 ketohexokinase activity(GO:0004454)
1.3 4.0 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
1.3 7.8 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
1.2 4.9 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.9 2.7 GO:0032139 DNA polymerase processivity factor activity(GO:0030337) dinucleotide insertion or deletion binding(GO:0032139)
0.8 2.5 GO:0019120 hydrolase activity, acting on acid halide bonds(GO:0016824) hydrolase activity, acting on acid halide bonds, in C-halide compounds(GO:0019120) alkylhalidase activity(GO:0047651)
0.8 2.5 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.6 4.4 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.6 1.8 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.5 2.1 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.4 3.0 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.4 1.1 GO:0009041 uridylate kinase activity(GO:0009041)
0.3 1.5 GO:0000405 bubble DNA binding(GO:0000405)
0.3 2.4 GO:1990239 steroid hormone binding(GO:1990239)
0.3 2.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.3 0.9 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.3 1.3 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.2 1.2 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.2 2.6 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 3.4 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.2 2.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.2 3.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) mitogen-activated protein kinase p38 binding(GO:0048273)
0.2 2.9 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 0.6 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.2 0.5 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.2 3.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2 0.6 GO:0043546 molybdenum ion binding(GO:0030151) molybdopterin cofactor binding(GO:0043546)
0.1 1.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 1.9 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 1.8 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 1.2 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 0.6 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 0.5 GO:0019863 IgE binding(GO:0019863)
0.1 2.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.3 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.1 3.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 5.2 GO:0016836 hydro-lyase activity(GO:0016836)
0.1 0.6 GO:0070051 fibrinogen binding(GO:0070051)
0.1 0.4 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1 0.5 GO:0046978 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.1 1.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 1.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 2.3 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.3 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 8.7 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 1.1 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.1 0.8 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 0.7 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 1.3 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 0.6 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.5 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 0.2 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.1 0.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.2 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.2 GO:0004658 propionyl-CoA carboxylase activity(GO:0004658)
0.1 1.8 GO:0008198 ferrous iron binding(GO:0008198)
0.0 5.3 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.8 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 3.6 GO:0005125 cytokine activity(GO:0005125)
0.0 0.2 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 2.3 GO:0019003 GDP binding(GO:0019003)
0.0 0.5 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.8 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.5 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 4.5 GO:0030165 PDZ domain binding(GO:0030165)
0.0 11.8 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.6 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0071208 histone pre-mRNA DCP binding(GO:0071208) U7 snRNA binding(GO:0071209)
0.0 1.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 1.1 GO:0005179 hormone activity(GO:0005179)
0.0 0.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.6 GO:0003678 DNA helicase activity(GO:0003678)
0.0 2.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.6 GO:0019239 deaminase activity(GO:0019239)
0.0 0.9 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.7 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.5 GO:0016651 oxidoreductase activity, acting on NAD(P)H(GO:0016651)
0.0 0.6 GO:0000049 tRNA binding(GO:0000049)
0.0 4.7 GO:0003682 chromatin binding(GO:0003682)
0.0 1.8 GO:0003735 structural constituent of ribosome(GO:0003735)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.5 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 6.4 PID_BARD1_PATHWAY BARD1 signaling events
0.1 4.3 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.1 6.0 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.1 6.5 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.1 2.6 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.1 2.3 ST_GA12_PATHWAY G alpha 12 Pathway
0.1 3.0 PID_RAS_PATHWAY Regulation of Ras family activation
0.1 2.1 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.1 2.9 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 1.8 PID_CD8_TCR_PATHWAY TCR signaling in naïve CD8+ T cells
0.1 4.0 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.1 3.1 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 1.5 PID_ATR_PATHWAY ATR signaling pathway
0.0 1.1 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.0 0.6 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.0 2.6 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.4 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 2.9 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.8 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.7 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.1 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 0.9 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 0.5 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.6 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 0.8 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.5 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 0.4 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.7 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.8 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.3 PID_TCPTP_PATHWAY Signaling events mediated by TCPTP

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.1 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.3 2.7 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.3 6.1 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.2 4.4 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.2 7.9 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.2 3.0 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 1.5 REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.2 3.0 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.1 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 1.0 REACTOME_TRAF6_MEDIATED_INDUCTION_OF_TAK1_COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.1 5.1 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 6.0 REACTOME_G1_PHASE Genes involved in G1 Phase
0.1 2.1 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 3.1 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 1.5 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.1 4.2 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.2 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 1.5 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 0.8 REACTOME_DOUBLE_STRAND_BREAK_REPAIR Genes involved in Double-Strand Break Repair
0.1 2.6 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.1 2.4 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.1 0.5 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 0.8 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 1.4 REACTOME_KINESINS Genes involved in Kinesins
0.1 0.6 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 2.9 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 1.1 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.0 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 Genes involved in Activation of Genes by ATF4
0.0 2.3 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.5 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 1.1 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.7 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.4 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.1 REACTOME_TRANSPORT_OF_GLUCOSE_AND_OTHER_SUGARS_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS Genes involved in Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
0.0 3.3 REACTOME_METABOLISM_OF_CARBOHYDRATES Genes involved in Metabolism of carbohydrates
0.0 1.3 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.2 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 0.4 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.8 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.5 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)