Motif ID: Sp100

Z-value: 3.301


Transcription factors associated with Sp100:

Gene SymbolEntrez IDGene Name
Sp100 ENSMUSG00000026222.10 Sp100

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sp100mm10_v2_chr1_+_85650044_856500520.134.3e-01Click!


Activity profile for motif Sp100.

activity profile for motif Sp100


Sorted Z-values histogram for motif Sp100

Sorted Z-values for motif Sp100



Network of associatons between targets according to the STRING database.



First level regulatory network of Sp100

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_+_3023547 68.043 ENSMUST00000099046.3
Gm10718
predicted gene 10718
chr9_+_3013140 66.668 ENSMUST00000143083.2
Gm10721
predicted gene 10721
chr14_-_19418930 59.411 ENSMUST00000177817.1
Gm21738
predicted gene, 21738
chr9_+_3025417 58.325 ENSMUST00000075573.6
Gm10717
predicted gene 10717
chr2_-_98667264 52.832 ENSMUST00000099683.1
Gm10800
predicted gene 10800
chr9_+_3018753 52.152 ENSMUST00000179272.1
Gm10719
predicted gene 10719
chr9_+_3004457 51.679 ENSMUST00000178348.1
Gm11168
predicted gene 11168
chr9_+_3017408 49.580 ENSMUST00000099049.3
Gm10719
predicted gene 10719
chr9_+_3036877 41.335 ENSMUST00000155807.2
Gm10715
predicted gene 10715
chr9_+_3027439 41.014 ENSMUST00000177875.1
ENSMUST00000179982.1
Gm10717

predicted gene 10717

chr9_+_3000922 40.511 ENSMUST00000151376.2
Gm10722
predicted gene 10722
chr9_+_3015654 35.860 ENSMUST00000099050.3
Gm10720
predicted gene 10720
chr8_+_94179089 26.206 ENSMUST00000034215.6
Mt1
metallothionein 1
chr10_-_42583628 16.741 ENSMUST00000019938.4
Nr2e1
nuclear receptor subfamily 2, group E, member 1
chr13_-_23762378 14.013 ENSMUST00000091701.2
Hist1h3a
histone cluster 1, H3a
chr16_-_17125106 13.710 ENSMUST00000093336.6
2610318N02Rik
RIKEN cDNA 2610318N02 gene
chr3_+_135212557 12.354 ENSMUST00000062893.7
Cenpe
centromere protein E
chr3_-_88410295 12.254 ENSMUST00000056370.7
Pmf1
polyamine-modulated factor 1
chr4_+_63215402 10.471 ENSMUST00000036300.6
Col27a1
collagen, type XXVII, alpha 1
chr8_-_4779513 10.351 ENSMUST00000022945.7
Shcbp1
Shc SH2-domain binding protein 1
chr9_-_36726374 9.456 ENSMUST00000172702.2
ENSMUST00000172742.1
ENSMUST00000034625.5
Chek1


checkpoint kinase 1


chr16_-_33380717 9.430 ENSMUST00000180923.1
1700007L15Rik
RIKEN cDNA 1700007L15 gene
chr16_-_22161450 9.137 ENSMUST00000115379.1
Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr7_+_67647405 9.102 ENSMUST00000032774.8
ENSMUST00000107471.1
Ttc23

tetratricopeptide repeat domain 23

chr14_+_65806066 9.050 ENSMUST00000139644.1
Pbk
PDZ binding kinase
chr5_-_135251209 8.528 ENSMUST00000062572.2
Fzd9
frizzled homolog 9 (Drosophila)
chr2_-_168767136 8.525 ENSMUST00000029061.5
ENSMUST00000103074.1
Sall4

sal-like 4 (Drosophila)

chr2_+_152736244 8.433 ENSMUST00000038368.8
ENSMUST00000109824.1
Id1

inhibitor of DNA binding 1

chr13_-_22041352 8.171 ENSMUST00000102977.2
Hist1h4i
histone cluster 1, H4i
chr4_+_105157339 8.033 ENSMUST00000064139.7
Ppap2b
phosphatidic acid phosphatase type 2B
chr14_+_73237891 7.218 ENSMUST00000044405.6
Lpar6
lysophosphatidic acid receptor 6
chr12_+_3891728 7.178 ENSMUST00000172689.1
ENSMUST00000111186.1
Dnmt3a

DNA methyltransferase 3A

chr7_+_144838590 7.125 ENSMUST00000105898.1
Fgf3
fibroblast growth factor 3
chr2_-_129297205 6.771 ENSMUST00000052708.6
Ckap2l
cytoskeleton associated protein 2-like
chr17_+_47505149 6.629 ENSMUST00000183177.1
ENSMUST00000182848.1
Ccnd3

cyclin D3

chr2_-_119618455 6.399 ENSMUST00000123818.1
Oip5
Opa interacting protein 5
chr9_+_60794468 6.219 ENSMUST00000050183.6
Uaca
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr11_-_11808923 6.200 ENSMUST00000109664.1
ENSMUST00000150714.1
ENSMUST00000047689.4
ENSMUST00000171938.1
ENSMUST00000171080.1
Fignl1




fidgetin-like 1




chr18_+_60911757 6.156 ENSMUST00000040359.5
Arsi
arylsulfatase i
chr12_-_74316394 6.108 ENSMUST00000110441.1
Gm11042
predicted gene 11042
chrX_+_56779699 6.042 ENSMUST00000114772.2
ENSMUST00000114768.3
ENSMUST00000155882.1
Fhl1


four and a half LIM domains 1


chr12_+_52097737 5.958 ENSMUST00000040090.9
Nubpl
nucleotide binding protein-like
chr19_+_38931008 5.938 ENSMUST00000145051.1
Hells
helicase, lymphoid specific
chr14_-_67715585 5.870 ENSMUST00000163100.1
ENSMUST00000132705.1
ENSMUST00000124045.1
Cdca2


cell division cycle associated 2


chr1_-_93342734 5.816 ENSMUST00000027493.3
Pask
PAS domain containing serine/threonine kinase
chr5_-_129787175 5.780 ENSMUST00000031399.6
Psph
phosphoserine phosphatase
chr19_+_38930909 5.758 ENSMUST00000025965.5
Hells
helicase, lymphoid specific
chr9_+_25089422 5.740 ENSMUST00000086238.2
Gm10181
predicted gene 10181
chr14_-_25927250 5.663 ENSMUST00000100811.5
Tmem254a
transmembrane protein 254a
chr15_+_85859689 5.558 ENSMUST00000170629.1
Gtse1
G two S phase expressed protein 1
chr6_-_23132981 5.553 ENSMUST00000031707.7
Aass
aminoadipate-semialdehyde synthase
chr2_-_25224653 5.523 ENSMUST00000043584.4
Tubb4b
tubulin, beta 4B class IVB
chr16_+_33829624 5.507 ENSMUST00000115028.3
Itgb5
integrin beta 5
chrX_+_56779437 5.401 ENSMUST00000114773.3
Fhl1
four and a half LIM domains 1
chr9_+_109832998 5.120 ENSMUST00000119376.1
ENSMUST00000122343.1
Nme6

NME/NM23 nucleoside diphosphate kinase 6

chr1_-_161251153 5.111 ENSMUST00000051925.4
ENSMUST00000071718.5
Prdx6

peroxiredoxin 6

chr5_+_9100681 5.080 ENSMUST00000115365.1
Tmem243
transmembrane protein 243, mitochondrial
chr10_-_41490335 4.821 ENSMUST00000019965.6
Smpd2
sphingomyelin phosphodiesterase 2, neutral
chr4_-_15945359 4.776 ENSMUST00000029877.8
Decr1
2,4-dienoyl CoA reductase 1, mitochondrial
chr10_+_25359798 4.775 ENSMUST00000053748.8
Epb4.1l2
erythrocyte protein band 4.1-like 2
chr17_+_47505211 4.738 ENSMUST00000182935.1
ENSMUST00000182506.1
Ccnd3

cyclin D3

chr9_+_109832749 4.697 ENSMUST00000147777.1
ENSMUST00000035053.5
ENSMUST00000133483.1
Nme6


NME/NM23 nucleoside diphosphate kinase 6


chr5_-_52566264 4.683 ENSMUST00000039750.5
Lgi2
leucine-rich repeat LGI family, member 2
chr13_+_23575753 4.549 ENSMUST00000105105.1
Hist1h3d
histone cluster 1, H3d
chr5_+_136919137 4.540 ENSMUST00000181045.1
4933404O12Rik
RIKEN cDNA 4933404O12 gene
chr4_+_128727585 4.436 ENSMUST00000106079.3
ENSMUST00000133439.1
Phc2

polyhomeotic-like 2 (Drosophila)

chr12_+_59013379 4.374 ENSMUST00000021379.7
Gemin2
gem (nuclear organelle) associated protein 2
chr2_+_75659253 4.297 ENSMUST00000111964.1
ENSMUST00000111962.1
ENSMUST00000111961.1
ENSMUST00000164947.2
ENSMUST00000090792.4
Hnrnpa3




heterogeneous nuclear ribonucleoprotein A3




chr8_-_105471481 4.069 ENSMUST00000014990.6
Tppp3
tubulin polymerization-promoting protein family member 3
chr14_-_87141206 3.936 ENSMUST00000022599.7
Diap3
diaphanous homolog 3 (Drosophila)
chr2_-_106003549 3.923 ENSMUST00000102555.4
Dnajc24
DnaJ (Hsp40) homolog, subfamily C, member 24
chr5_-_149053038 3.896 ENSMUST00000085546.6
Hmgb1
high mobility group box 1
chr5_+_21785253 3.849 ENSMUST00000030769.5
Psmc2
proteasome (prosome, macropain) 26S subunit, ATPase 2
chr18_+_61045139 3.715 ENSMUST00000025522.4
ENSMUST00000115274.1
Pdgfrb

platelet derived growth factor receptor, beta polypeptide

chr2_+_105904629 3.708 ENSMUST00000037499.5
Immp1l
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr18_+_34624621 3.688 ENSMUST00000167161.1
Kif20a
kinesin family member 20A
chr7_-_131327325 3.688 ENSMUST00000033146.7
1700007K09Rik
RIKEN cDNA 1700007K09 gene
chr13_+_23746734 3.652 ENSMUST00000099703.2
Hist1h2bb
histone cluster 1, H2bb
chr14_-_87141114 3.645 ENSMUST00000168889.1
Diap3
diaphanous homolog 3 (Drosophila)
chr17_+_33524170 3.617 ENSMUST00000087623.6
Adamts10
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 10
chr13_-_104228833 3.575 ENSMUST00000022226.4
Ppwd1
peptidylprolyl isomerase domain and WD repeat containing 1
chr14_+_57798182 3.500 ENSMUST00000111269.1
Sap18
Sin3-associated polypeptide 18
chr4_-_14621805 3.412 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr2_+_62664279 3.412 ENSMUST00000028257.2
Gca
grancalcin
chr14_-_62456286 3.352 ENSMUST00000165651.1
ENSMUST00000022501.3
Gucy1b2

guanylate cyclase 1, soluble, beta 2

chr6_-_112696604 3.349 ENSMUST00000113182.1
ENSMUST00000113180.1
ENSMUST00000068487.5
ENSMUST00000077088.4
Rad18



RAD18 homolog (S. cerevisiae)



chr4_+_105789869 3.319 ENSMUST00000184254.1
Gm12728
predicted gene 12728
chr15_+_44196135 3.316 ENSMUST00000038856.6
ENSMUST00000110289.3
Trhr

thyrotropin releasing hormone receptor

chr2_-_102186322 3.310 ENSMUST00000111222.1
ENSMUST00000058790.5
Ldlrad3

low density lipoprotein receptor class A domain containing 3

chr15_-_81926148 3.164 ENSMUST00000023113.5
Polr3h
polymerase (RNA) III (DNA directed) polypeptide H
chr11_+_78176711 3.154 ENSMUST00000098545.5
Tlcd1
TLC domain containing 1
chr3_+_90248172 3.135 ENSMUST00000015467.8
Slc39a1
solute carrier family 39 (zinc transporter), member 1
chr5_-_138272786 3.052 ENSMUST00000161279.1
ENSMUST00000161647.1
Gal3st4

galactose-3-O-sulfotransferase 4

chr8_+_70673364 3.020 ENSMUST00000146972.1
Lsm4
LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr15_+_27025386 3.004 ENSMUST00000169678.2
Gm6576
predicted gene 6576
chr11_+_94211431 2.971 ENSMUST00000041589.5
Tob1
transducer of ErbB-2.1
chr4_+_63558748 2.811 ENSMUST00000077709.4
6330416G13Rik
RIKEN cDNA 6330416G13 gene
chr4_-_14621669 2.801 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chrX_-_143827391 2.776 ENSMUST00000087316.5
Capn6
calpain 6
chr2_-_51934644 2.607 ENSMUST00000165313.1
Rbm43
RNA binding motif protein 43
chr7_+_4792874 2.598 ENSMUST00000032597.5
ENSMUST00000078432.4
Rpl28

ribosomal protein L28

chrX_-_104671048 2.597 ENSMUST00000042070.5
Zdhhc15
zinc finger, DHHC domain containing 15
chr4_-_25800083 2.552 ENSMUST00000084770.4
Fut9
fucosyltransferase 9
chr10_-_86705485 2.551 ENSMUST00000020238.7
Hsp90b1
heat shock protein 90, beta (Grp94), member 1
chr9_+_83925118 2.517 ENSMUST00000034801.4
Bckdhb
branched chain ketoacid dehydrogenase E1, beta polypeptide
chr10_+_80249106 2.442 ENSMUST00000105364.1
Ndufs7
NADH dehydrogenase (ubiquinone) Fe-S protein 7
chr11_-_116138862 2.387 ENSMUST00000106439.1
Mrpl38
mitochondrial ribosomal protein L38
chr17_-_46782640 2.374 ENSMUST00000078286.5
Rpl7l1
ribosomal protein L7-like 1
chr17_-_10320229 2.354 ENSMUST00000053066.6
Qk
quaking
chr2_+_72297895 2.308 ENSMUST00000144111.1
Zak
sterile alpha motif and leucine zipper containing kinase AZK
chr2_-_105904484 2.265 ENSMUST00000122965.1
Elp4
elongation protein 4 homolog (S. cerevisiae)
chr9_+_120571498 2.259 ENSMUST00000165532.1
Rpl14
ribosomal protein L14
chr11_-_102407899 2.214 ENSMUST00000124755.1
Slc25a39
solute carrier family 25, member 39
chr10_+_80249441 2.175 ENSMUST00000020361.6
Ndufs7
NADH dehydrogenase (ubiquinone) Fe-S protein 7
chrX_-_56822308 2.168 ENSMUST00000135542.1
ENSMUST00000114766.1
Mtap7d3

MAP7 domain containing 3

chr6_-_117907753 2.163 ENSMUST00000035534.4
4933440N22Rik
RIKEN cDNA 4933440N22 gene
chr8_+_117498272 2.143 ENSMUST00000081232.7
Plcg2
phospholipase C, gamma 2
chr11_-_16508149 2.142 ENSMUST00000109642.1
Sec61g
SEC61, gamma subunit
chr5_-_92278155 2.097 ENSMUST00000159345.1
ENSMUST00000113102.3
Naaa

N-acylethanolamine acid amidase

chr14_+_50807915 2.075 ENSMUST00000036126.5
Parp2
poly (ADP-ribose) polymerase family, member 2
chr13_+_21180179 2.072 ENSMUST00000021761.5
Trim27
tripartite motif-containing 27
chr11_-_78176619 2.043 ENSMUST00000148154.2
ENSMUST00000017549.6
Nek8

NIMA (never in mitosis gene a)-related expressed kinase 8

chr11_-_119300004 2.033 ENSMUST00000106253.1
Eif4a3
eukaryotic translation initiation factor 4A3
chr2_-_86347764 1.992 ENSMUST00000099894.2
Olfr1055
olfactory receptor 1055
chr11_-_119300070 1.950 ENSMUST00000026667.8
Eif4a3
eukaryotic translation initiation factor 4A3
chr5_-_21785115 1.949 ENSMUST00000115193.1
ENSMUST00000115192.1
ENSMUST00000115195.1
ENSMUST00000030771.5
Dnajc2



DnaJ (Hsp40) homolog, subfamily C, member 2



chr17_-_10840285 1.915 ENSMUST00000041463.6
Pacrg
PARK2 co-regulated
chr6_-_57692007 1.876 ENSMUST00000053386.5
ENSMUST00000185014.1
Pyurf
PYURF
Pigy upstream reading frame
protein preY, mitochondrial precursor
chr9_-_21312255 1.844 ENSMUST00000115433.3
ENSMUST00000003397.7
Ap1m2

adaptor protein complex AP-1, mu 2 subunit

chr12_+_9029982 1.798 ENSMUST00000085741.1
Ttc32
tetratricopeptide repeat domain 32
chr14_+_75845296 1.795 ENSMUST00000142061.1
Tpt1
tumor protein, translationally-controlled 1
chr5_-_145191511 1.763 ENSMUST00000161845.1
Atp5j2
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F2
chr5_+_137745967 1.733 ENSMUST00000100539.3
Tsc22d4
TSC22 domain family, member 4
chr13_-_32338565 1.733 ENSMUST00000041859.7
Gmds
GDP-mannose 4, 6-dehydratase
chr14_+_57798637 1.726 ENSMUST00000111267.1
Sap18
Sin3-associated polypeptide 18
chr2_-_140170528 1.694 ENSMUST00000046030.7
Esf1
ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
chr16_-_56029696 1.683 ENSMUST00000122253.1
ENSMUST00000114444.2
Pcnp

PEST proteolytic signal containing nuclear protein

chr17_+_24669730 1.681 ENSMUST00000047179.5
Zfp598
zinc finger protein 598
chr4_-_25281801 1.671 ENSMUST00000102994.3
Ufl1
UFM1 specific ligase 1
chr17_+_56079652 1.623 ENSMUST00000002911.8
Hdgfrp2
hepatoma-derived growth factor, related protein 2
chr6_+_134981998 1.609 ENSMUST00000167323.1
Apold1
apolipoprotein L domain containing 1
chr4_-_25800239 1.587 ENSMUST00000108199.1
Fut9
fucosyltransferase 9
chr4_-_126202757 1.569 ENSMUST00000080919.5
Thrap3
thyroid hormone receptor associated protein 3
chr5_-_24445166 1.569 ENSMUST00000115043.1
ENSMUST00000115041.1
Fastk

Fas-activated serine/threonine kinase

chr1_-_34439672 1.539 ENSMUST00000042493.8
Ccdc115
coiled-coil domain containing 115
chr16_+_65520503 1.537 ENSMUST00000176330.1
ENSMUST00000004964.8
ENSMUST00000176038.1
Pou1f1


POU domain, class 1, transcription factor 1


chr8_+_95534078 1.533 ENSMUST00000041569.3
Ccdc113
coiled-coil domain containing 113
chr10_+_111125851 1.513 ENSMUST00000171120.1
Gm5428
predicted gene 5428
chr13_+_74406387 1.506 ENSMUST00000090860.6
Gm10116
predicted pseudogene 10116
chr17_-_74323896 1.493 ENSMUST00000164832.1
Dpy30
dpy-30 homolog (C. elegans)
chr11_-_16508069 1.369 ENSMUST00000109641.1
Sec61g
SEC61, gamma subunit
chr14_-_33978751 1.364 ENSMUST00000166737.1
Zfp488
zinc finger protein 488
chr19_+_11770415 1.335 ENSMUST00000167199.1
Mrpl16
mitochondrial ribosomal protein L16
chr14_+_57798156 1.294 ENSMUST00000128764.1
Sap18
Sin3-associated polypeptide 18
chr8_+_22411340 1.279 ENSMUST00000033934.3
Mrps31
mitochondrial ribosomal protein S31
chr6_+_87009836 1.276 ENSMUST00000032060.8
ENSMUST00000117583.1
ENSMUST00000144776.1
Nfu1


NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)


chr14_+_11227511 1.275 ENSMUST00000080237.3
Rpl21-ps4
ribosomal protein L21, pseudogene 4
chr12_+_75308308 1.262 ENSMUST00000118602.1
ENSMUST00000118966.1
ENSMUST00000055390.5
Rhoj


ras homolog gene family, member J


chr2_+_174330006 1.258 ENSMUST00000109085.1
ENSMUST00000109087.1
ENSMUST00000109084.1
Gnas


GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus


chr8_-_70897407 1.250 ENSMUST00000054220.8
Rpl18a
ribosomal protein L18A
chr7_-_133776772 1.247 ENSMUST00000033290.5
Dhx32
DEAH (Asp-Glu-Ala-His) box polypeptide 32
chr2_-_4141128 1.232 ENSMUST00000154360.1
ENSMUST00000141488.1
ENSMUST00000155091.1
1700080N15Rik


RIKEN cDNA 1700080N15 gene


chr11_+_77686155 1.229 ENSMUST00000100802.4
ENSMUST00000181023.1
Nufip2

nuclear fragile X mental retardation protein interacting protein 2

chr16_+_10411928 1.228 ENSMUST00000023146.4
Nubp1
nucleotide binding protein 1
chr1_+_131962941 1.200 ENSMUST00000177943.1
Slc45a3
solute carrier family 45, member 3
chr17_-_22867075 1.198 ENSMUST00000150092.1
Zfp945
zinc finger protein 945
chr11_-_120086790 1.183 ENSMUST00000106227.1
ENSMUST00000106229.1
ENSMUST00000180242.1
Azi1


5-azacytidine induced gene 1


chr4_-_147868631 1.154 ENSMUST00000030886.8
ENSMUST00000172710.1
Miip

migration and invasion inhibitory protein

chr13_+_23934434 1.129 ENSMUST00000072391.1
Hist1h2aa
histone cluster 1, H2aa
chr14_+_56668242 1.094 ENSMUST00000116468.1
Mphosph8
M-phase phosphoprotein 8
chr5_-_24445254 1.071 ENSMUST00000030800.6
Fastk
Fas-activated serine/threonine kinase
chr5_-_124352233 1.061 ENSMUST00000111472.1
Cdk2ap1
CDK2 (cyclin-dependent kinase 2)-associated protein 1
chr7_-_84679346 1.055 ENSMUST00000069537.2
ENSMUST00000178385.1
Zfand6

zinc finger, AN1-type domain 6

chr7_-_5413145 1.044 ENSMUST00000108569.2
Vmn1r58
vomeronasal 1 receptor 58
chr13_-_35027077 1.027 ENSMUST00000170538.1
ENSMUST00000163280.1
Eci2

enoyl-Coenzyme A delta isomerase 2

chr10_+_87859062 1.009 ENSMUST00000095360.4
Igf1
insulin-like growth factor 1
chr11_+_51584757 1.003 ENSMUST00000167797.1
ENSMUST00000020625.6
Phykpl

5-phosphohydroxy-L-lysine phospholyase

chr5_+_16553488 0.983 ENSMUST00000030683.3
Hgf
hepatocyte growth factor
chr1_+_171411343 0.981 ENSMUST00000160486.1
Usf1
upstream transcription factor 1
chr11_+_72441341 0.977 ENSMUST00000045633.5
Mybbp1a
MYB binding protein (P160) 1a
chr12_+_98771018 0.892 ENSMUST00000021399.7
Zc3h14
zinc finger CCCH type containing 14
chr10_+_60399726 0.886 ENSMUST00000164428.1
Gm17455
predicted gene, 17455
chr6_+_18848571 0.878 ENSMUST00000056398.8
Naa38
N(alpha)-acetyltransferase 38, NatC auxiliary subunit
chr9_-_49486209 0.872 ENSMUST00000055096.4
Ttc12
tetratricopeptide repeat domain 12
chr14_-_105176860 0.866 ENSMUST00000163545.1
Rbm26
RNA binding motif protein 26
chr8_+_107056870 0.852 ENSMUST00000034392.5
ENSMUST00000170962.1
Nip7

nuclear import 7 homolog (S. cerevisiae)

chr4_+_21727726 0.808 ENSMUST00000102997.1
ENSMUST00000120679.1
ENSMUST00000108240.2
Ccnc


cyclin C


chr8_+_114439655 0.794 ENSMUST00000004756.7
ENSMUST00000109108.2
ENSMUST00000160862.1
ENSMUST00000109107.2
Wwox



WW domain-containing oxidoreductase



chr10_-_128891674 0.740 ENSMUST00000026408.6
Gdf11
growth differentiation factor 11
chr7_-_46710642 0.722 ENSMUST00000143082.1
Saal1
serum amyloid A-like 1
chr4_+_155624853 0.719 ENSMUST00000067081.3
ENSMUST00000105600.1
ENSMUST00000105598.1
Cdk11b


cyclin-dependent kinase 11B


chr3_+_41024369 0.705 ENSMUST00000099121.3
Larp1b
La ribonucleoprotein domain family, member 1B
chr5_-_134456227 0.689 ENSMUST00000111244.1
Gtf2ird1
general transcription factor II I repeat domain-containing 1
chr15_-_77970750 0.686 ENSMUST00000100484.4
Eif3d
eukaryotic translation initiation factor 3, subunit D
chr12_-_81421910 0.682 ENSMUST00000085319.3
Adam4
a disintegrin and metallopeptidase domain 4
chr5_+_52834009 0.601 ENSMUST00000031072.7
Anapc4
anaphase promoting complex subunit 4
chr13_-_30545254 0.592 ENSMUST00000042834.3
Uqcrfs1
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
chr6_+_7555053 0.571 ENSMUST00000090679.2
ENSMUST00000184986.1
Tac1

tachykinin 1

chr13_-_108158584 0.547 ENSMUST00000163558.1
Ndufaf2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 2
chr2_+_166792525 0.521 ENSMUST00000065753.1
Trp53rk
transformation related protein 53 regulating kinase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 26.2 GO:0010273 detoxification of copper ion(GO:0010273) cellular response to zinc ion(GO:0071294) stress response to copper ion(GO:1990169)
3.3 16.7 GO:0021764 amygdala development(GO:0021764)
2.8 8.5 GO:1990523 bone regeneration(GO:1990523)
2.1 12.4 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
1.9 5.6 GO:0006553 lysine metabolic process(GO:0006553)
1.7 10.5 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
1.3 4.0 GO:1904569 regulation of selenocysteine incorporation(GO:1904569)
1.3 3.9 GO:0045819 plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819)
1.3 18.9 GO:0010216 maintenance of DNA methylation(GO:0010216)
1.2 3.7 GO:0035441 cell migration involved in vasculogenesis(GO:0035441) metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
1.2 8.4 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
1.2 5.8 GO:0006564 L-serine biosynthetic process(GO:0006564)
1.1 6.4 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
1.1 9.5 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
1.0 7.1 GO:0030916 otic vesicle formation(GO:0030916)
0.9 9.8 GO:0006228 UTP biosynthetic process(GO:0006228)
0.9 6.2 GO:0019532 oxalate transport(GO:0019532)
0.9 26.7 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.7 2.1 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.6 5.8 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.6 3.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.6 11.4 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.5 3.7 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.5 1.5 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.5 8.6 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.5 1.8 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.4 1.8 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.4 2.1 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
0.4 3.3 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.4 1.2 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.4 6.2 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.4 3.9 GO:0031441 negative regulation of mRNA 3'-end processing(GO:0031441)
0.3 1.0 GO:1900141 regulation of oligodendrocyte apoptotic process(GO:1900141) negative regulation of oligodendrocyte apoptotic process(GO:1900142)
0.3 7.2 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.3 5.5 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.3 12.6 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.3 3.8 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.3 4.1 GO:0036065 fucosylation(GO:0036065)
0.3 1.7 GO:1990564 protein ufmylation(GO:0071569) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.3 5.1 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.3 2.6 GO:0071318 cellular response to ATP(GO:0071318)
0.3 1.3 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.2 10.6 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.2 1.2 GO:0072697 protein localization to cell cortex(GO:0072697)
0.2 2.1 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.2 6.2 GO:0033687 osteoblast proliferation(GO:0033687)
0.2 0.7 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.2 3.3 GO:0051984 positive regulation of chromosome segregation(GO:0051984)
0.2 7.4 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.2 1.0 GO:0046016 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) late viral transcription(GO:0019086) positive regulation of transcription by glucose(GO:0046016)
0.2 1.0 GO:2000210 positive regulation of anoikis(GO:2000210)
0.2 1.7 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.2 1.7 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.2 0.6 GO:0035934 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.2 1.5 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.2 2.0 GO:0035330 regulation of hippo signaling(GO:0035330)
0.2 2.4 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.2 2.4 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.2 1.5 GO:1905146 lysosomal protein catabolic process(GO:1905146)
0.2 3.1 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.2 0.5 GO:0036090 cleavage furrow ingression(GO:0036090)
0.1 2.5 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 2.6 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.1 0.7 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 1.3 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 3.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 1.0 GO:0060665 cellular response to hepatocyte growth factor stimulus(GO:0035729) regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 8.9 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435)
0.1 5.9 GO:0035307 positive regulation of protein dephosphorylation(GO:0035307)
0.1 0.8 GO:1901409 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 1.7 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.1 11.9 GO:0051028 mRNA transport(GO:0051028)
0.1 3.4 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.1 0.4 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.6 GO:0030071 regulation of mitotic metaphase/anaphase transition(GO:0030071) regulation of metaphase/anaphase transition of cell cycle(GO:1902099)
0.1 2.2 GO:0006783 heme biosynthetic process(GO:0006783)
0.1 0.4 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1 1.4 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.1 1.3 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 4.1 GO:0046785 microtubule polymerization(GO:0046785)
0.1 1.1 GO:0044030 regulation of DNA methylation(GO:0044030)
0.1 2.3 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 0.5 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 3.3 GO:0070613 regulation of protein processing(GO:0070613)
0.0 1.6 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.0 10.5 GO:0007059 chromosome segregation(GO:0007059)
0.0 0.3 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 3.4 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 2.1 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 1.2 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 0.4 GO:1990173 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.0 1.4 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.4 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.7 GO:0021511 spinal cord patterning(GO:0021511)
0.0 1.5 GO:0032543 mitochondrial translation(GO:0032543)
0.0 1.5 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 1.1 GO:0060325 face morphogenesis(GO:0060325)
0.0 1.8 GO:0015992 proton transport(GO:0015992)
0.0 0.1 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.0 1.0 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.0 0.7 GO:0007088 regulation of mitotic nuclear division(GO:0007088)
0.0 0.3 GO:0019363 pyridine nucleotide biosynthetic process(GO:0019363)
0.0 1.1 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.3 GO:0006625 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.9 GO:0010923 negative regulation of phosphatase activity(GO:0010923)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 12.3 GO:0000444 MIS12/MIND type complex(GO:0000444)
1.8 5.5 GO:0034684 integrin alphav-beta5 complex(GO:0034684)
1.6 6.2 GO:0043293 apoptosome(GO:0043293)
1.2 3.7 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
1.2 12.4 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.9 10.5 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.8 24.5 GO:0000788 nuclear nucleosome(GO:0000788)
0.7 4.4 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.7 6.5 GO:0061574 ASAP complex(GO:0061574)
0.7 2.0 GO:0097543 ciliary inversin compartment(GO:0097543)
0.7 6.5 GO:0045298 tubulin complex(GO:0045298)
0.6 2.5 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.5 4.1 GO:0097427 microtubule bundle(GO:0097427)
0.4 11.7 GO:0005721 pericentric heterochromatin(GO:0005721)
0.4 4.9 GO:0010369 chromocenter(GO:0010369)
0.4 10.5 GO:0001741 XY body(GO:0001741)
0.4 8.5 GO:0031527 filopodium membrane(GO:0031527)
0.4 3.8 GO:0031595 nuclear proteasome complex(GO:0031595)
0.3 1.0 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.3 1.0 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.3 2.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.3 0.9 GO:0031417 NatC complex(GO:0031417)
0.3 3.6 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.3 3.0 GO:0005688 U6 snRNP(GO:0005688)
0.3 1.5 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.2 4.4 GO:0035102 PRC1 complex(GO:0035102)
0.2 4.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.2 12.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 2.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 3.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 3.0 GO:0030014 CCR4-NOT complex(GO:0030014)
0.2 2.5 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 4.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 9.5 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.1 1.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 8.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 1.2 GO:0042788 polysomal ribosome(GO:0042788)
0.1 3.7 GO:0000786 nucleosome(GO:0000786)
0.1 1.9 GO:0097225 sperm midpiece(GO:0097225)
0.1 1.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 1.7 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.7 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 4.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 5.2 GO:0072686 mitotic spindle(GO:0072686)
0.1 3.7 GO:0005871 kinesin complex(GO:0005871)
0.1 2.1 GO:0030904 retromer complex(GO:0030904)
0.1 0.6 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 2.8 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 3.5 GO:0000792 heterochromatin(GO:0000792)
0.0 1.0 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 4.8 GO:0005901 caveola(GO:0005901)
0.0 1.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 1.3 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 2.2 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 3.6 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.5 GO:0070938 contractile ring(GO:0070938)
0.0 0.4 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 13.1 GO:0005925 focal adhesion(GO:0005925)
0.0 0.2 GO:0097255 R2TP complex(GO:0097255)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.9 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 315.1 GO:0005575 cellular_component(GO:0005575)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 9.5 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
2.5 12.4 GO:0043515 kinetochore binding(GO:0043515)
1.9 5.8 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
1.3 3.9 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
1.1 4.3 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
1.0 4.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
1.0 7.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.9 7.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.9 10.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.7 3.7 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.6 4.8 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.6 1.7 GO:0071568 UFM1 transferase activity(GO:0071568)
0.5 3.8 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.5 5.9 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.5 5.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.5 3.1 GO:0050694 galactose 3-O-sulfotransferase activity(GO:0050694)
0.5 3.0 GO:0042731 PH domain binding(GO:0042731)
0.5 4.0 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.5 26.2 GO:0005507 copper ion binding(GO:0005507)
0.5 9.8 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.5 3.3 GO:0000403 Y-form DNA binding(GO:0000403)
0.4 1.2 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.4 8.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.4 4.6 GO:0048038 quinone binding(GO:0048038)
0.3 2.1 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.3 2.0 GO:0004984 olfactory receptor activity(GO:0004984)
0.3 1.9 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.3 7.1 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.3 2.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.3 2.6 GO:0046790 virion binding(GO:0046790)
0.3 15.2 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.3 10.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.3 12.1 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.2 5.6 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.2 5.1 GO:0070628 proteasome binding(GO:0070628)
0.2 2.5 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.2 8.5 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.2 4.8 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.2 6.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.2 16.7 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.2 1.2 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.2 3.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 3.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.2 0.8 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.1 0.4 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.1 2.1 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 5.0 GO:0042169 SH2 domain binding(GO:0042169)
0.1 3.9 GO:0001671 ATPase activator activity(GO:0001671)
0.1 2.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.4 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1 1.7 GO:0001056 RNA polymerase III activity(GO:0001056)
0.1 3.6 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 1.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 0.7 GO:0000339 RNA cap binding(GO:0000339)
0.1 2.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.6 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 1.9 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 4.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 6.5 GO:0005178 integrin binding(GO:0005178)
0.1 9.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 1.0 GO:0008483 transaminase activity(GO:0008483)
0.0 0.9 GO:0008143 poly(A) binding(GO:0008143)
0.0 1.0 GO:0042056 chemoattractant activity(GO:0042056)
0.0 1.0 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 3.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 2.3 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 7.8 GO:0042393 histone binding(GO:0042393)
0.0 1.1 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.6 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 1.7 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 3.7 GO:0008236 serine-type peptidase activity(GO:0008236)
0.0 1.9 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.1 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
0.0 1.4 GO:0043022 ribosome binding(GO:0043022)
0.0 0.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 1.2 GO:0008186 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 247.5 GO:0003674 molecular_function(GO:0003674)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 9.5 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.3 5.5 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.3 17.8 PID_PLK1_PATHWAY PLK1 signaling events
0.3 8.5 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.3 7.6 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.3 11.7 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 8.4 PID_ALK1_PATHWAY ALK1 signaling events
0.2 10.5 NABA_COLLAGENS Genes encoding collagen proteins
0.2 11.4 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.1 2.3 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 7.2 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.1 8.6 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.1 8.5 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 2.6 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.1 2.1 PID_EPO_PATHWAY EPO signaling pathway
0.1 1.0 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 2.9 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 1.0 PID_IGF1_PATHWAY IGF1 pathway
0.0 4.7 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.5 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 5.2 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 4.0 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.8 PID_P73PATHWAY p73 transcription factor network
0.0 1.1 ST_FAS_SIGNALING_PATHWAY Fas Signaling Pathway
0.0 0.7 PID_AR_PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 9.5 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.8 7.2 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.8 6.2 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.6 7.1 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.5 27.0 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.3 5.5 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.3 3.9 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.3 2.6 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.3 4.8 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.3 6.4 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.2 11.4 REACTOME_G1_PHASE Genes involved in G1 Phase
0.2 16.7 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.2 5.8 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.2 8.0 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.2 3.1 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.2 3.0 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.2 10.8 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.2 4.8 REACTOME_SPHINGOLIPID_METABOLISM Genes involved in Sphingolipid metabolism
0.1 5.5 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 3.7 REACTOME_KINESINS Genes involved in Kinesins
0.1 1.8 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 9.8 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 2.5 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 2.9 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.1 1.8 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 8.0 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 1.7 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 1.0 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.1 3.7 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.1 5.3 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.1 4.0 REACTOME_ER_PHAGOSOME_PATHWAY Genes involved in ER-Phagosome pathway
0.1 0.8 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 2.1 REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE Genes involved in GPVI-mediated activation cascade
0.0 5.5 REACTOME_3_UTR_MEDIATED_TRANSLATIONAL_REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.0 3.9 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 5.9 REACTOME_DIABETES_PATHWAYS Genes involved in Diabetes pathways
0.0 0.6 REACTOME_PHOSPHORYLATION_OF_THE_APC_C Genes involved in Phosphorylation of the APC/C
0.0 3.7 REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.4 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.8 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 2.3 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 1.8 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.2 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)