Motif ID: Hivep1

Z-value: 0.921


Transcription factors associated with Hivep1:

Gene SymbolEntrez IDGene Name
Hivep1 ENSMUSG00000021366.7 Hivep1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hivep1mm10_v2_chr13_+_42052015_420520720.491.3e-03Click!


Activity profile for motif Hivep1.

activity profile for motif Hivep1


Sorted Z-values histogram for motif Hivep1

Sorted Z-values for motif Hivep1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hivep1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_27616895 8.180 ENSMUST00000092639.5
Lama2
laminin, alpha 2
chr14_+_80000292 6.561 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr2_-_113758638 5.364 ENSMUST00000099575.3
Grem1
gremlin 1
chr3_-_88000350 4.571 ENSMUST00000090971.5
Bcan
brevican
chr7_+_99535652 4.210 ENSMUST00000032995.8
ENSMUST00000162404.1
Arrb1

arrestin, beta 1

chr3_-_107760221 3.919 ENSMUST00000153114.1
ENSMUST00000118593.1
ENSMUST00000120243.1
Csf1


colony stimulating factor 1 (macrophage)


chr6_-_97487801 3.519 ENSMUST00000113353.1
ENSMUST00000032146.7
Frmd4b

FERM domain containing 4B

chr7_+_99535439 3.429 ENSMUST00000098266.2
ENSMUST00000179755.1
Arrb1

arrestin, beta 1

chr1_-_156204998 3.408 ENSMUST00000015628.3
Fam163a
family with sequence similarity 163, member A
chr2_-_104257400 3.164 ENSMUST00000141159.1
D430041D05Rik
RIKEN cDNA D430041D05 gene
chr16_+_38089001 3.127 ENSMUST00000023507.6
Gsk3b
glycogen synthase kinase 3 beta
chr18_+_37496997 3.071 ENSMUST00000059571.5
Pcdhb19
protocadherin beta 19
chr4_-_82505749 2.848 ENSMUST00000107245.2
ENSMUST00000107246.1
Nfib

nuclear factor I/B

chr2_-_5063996 2.641 ENSMUST00000114996.1
Optn
optineurin
chr18_+_37477768 2.438 ENSMUST00000051442.5
Pcdhb16
protocadherin beta 16
chr2_+_130405256 2.424 ENSMUST00000110281.1
ENSMUST00000028898.3
1700020A23Rik

RIKEN cDNA 1700020A23 gene

chr3_-_53657339 2.404 ENSMUST00000091137.4
Frem2
Fras1 related extracellular matrix protein 2
chr5_-_134747241 2.247 ENSMUST00000015138.9
Eln
elastin
chr2_-_5063932 2.237 ENSMUST00000027986.4
Optn
optineurin
chr5_+_90759299 2.168 ENSMUST00000031318.4
Cxcl5
chemokine (C-X-C motif) ligand 5
chr1_-_36273425 2.155 ENSMUST00000056946.6
Neurl3
neuralized homolog 3 homolog (Drosophila)
chr6_-_136171722 2.106 ENSMUST00000053880.6
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr10_-_95415484 2.087 ENSMUST00000172070.1
ENSMUST00000150432.1
Socs2

suppressor of cytokine signaling 2

chr4_-_40239779 1.983 ENSMUST00000037907.6
Ddx58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chrX_-_8206475 1.920 ENSMUST00000089403.3
ENSMUST00000077595.5
ENSMUST00000089402.3
ENSMUST00000082320.5
Porcn



porcupine homolog (Drosophila)



chr7_+_82174796 1.844 ENSMUST00000032874.7
Sh3gl3
SH3-domain GRB2-like 3
chr5_+_138280516 1.844 ENSMUST00000048028.8
Stag3
stromal antigen 3
chr11_+_78188737 1.813 ENSMUST00000108322.2
Rab34
RAB34, member of RAS oncogene family
chr18_+_37484955 1.790 ENSMUST00000053856.4
Pcdhb17
protocadherin beta 17
chr2_+_32721055 1.733 ENSMUST00000074248.4
Sh2d3c
SH2 domain containing 3C
chr17_+_45555693 1.717 ENSMUST00000024742.7
Nfkbie
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon
chr13_+_42866247 1.685 ENSMUST00000131942.1
Phactr1
phosphatase and actin regulator 1
chr14_+_55560480 1.638 ENSMUST00000121622.1
ENSMUST00000143431.1
ENSMUST00000150481.1
Dcaf11


DDB1 and CUL4 associated factor 11


chr8_+_90828820 1.634 ENSMUST00000109614.2
ENSMUST00000048665.6
Chd9

chromodomain helicase DNA binding protein 9

chr7_+_97579868 1.632 ENSMUST00000042399.7
ENSMUST00000107153.1
Rsf1

remodeling and spacing factor 1

chr1_+_64532790 1.595 ENSMUST00000049932.5
ENSMUST00000087366.4
ENSMUST00000171164.1
Creb1


cAMP responsive element binding protein 1


chrX_-_8132770 1.553 ENSMUST00000130832.1
ENSMUST00000033506.6
ENSMUST00000115623.1
ENSMUST00000153839.1
Wdr13



WD repeat domain 13



chr6_-_8778106 1.520 ENSMUST00000151758.1
ENSMUST00000115519.1
ENSMUST00000153390.1
Ica1


islet cell autoantigen 1


chr10_+_115384951 1.484 ENSMUST00000036044.8
Zfc3h1
zinc finger, C3H1-type containing
chr10_+_7681197 1.467 ENSMUST00000165952.1
Lats1
large tumor suppressor
chr15_-_102529025 1.451 ENSMUST00000096143.1
Atf7
activating transcription factor 7
chr12_-_98577940 1.433 ENSMUST00000110113.1
Kcnk10
potassium channel, subfamily K, member 10
chr6_-_8778439 1.426 ENSMUST00000115520.1
ENSMUST00000038403.5
ENSMUST00000115518.1
Ica1


islet cell autoantigen 1


chr10_-_116972609 1.374 ENSMUST00000092165.4
Gm10271
predicted gene 10271
chr2_-_181459364 1.374 ENSMUST00000155535.1
ENSMUST00000029106.6
ENSMUST00000087409.3
Zbtb46


zinc finger and BTB domain containing 46


chr14_-_34503323 1.349 ENSMUST00000171343.1
Bmpr1a
bone morphogenetic protein receptor, type 1A
chr5_-_98030727 1.335 ENSMUST00000031281.9
Antxr2
anthrax toxin receptor 2
chr5_-_145201829 1.335 ENSMUST00000162220.1
ENSMUST00000031632.8
Zkscan14

zinc finger with KRAB and SCAN domains 14

chr12_+_85824918 1.317 ENSMUST00000040273.7
ENSMUST00000110224.1
ENSMUST00000142411.2
Ttll5


tubulin tyrosine ligase-like family, member 5


chr14_+_55560904 1.315 ENSMUST00000072530.4
ENSMUST00000128490.1
Dcaf11

DDB1 and CUL4 associated factor 11

chr11_+_93098404 1.309 ENSMUST00000107859.1
ENSMUST00000042943.6
ENSMUST00000107861.1
ENSMUST00000107858.2
Car10



carbonic anhydrase 10



chr11_-_100411874 1.280 ENSMUST00000141840.1
Leprel4
leprecan-like 4
chr15_-_79164477 1.277 ENSMUST00000040019.4
Sox10
SRY-box containing gene 10
chr2_-_45113255 1.274 ENSMUST00000068415.4
ENSMUST00000127520.1
Zeb2

zinc finger E-box binding homeobox 2

chr7_-_101302020 1.249 ENSMUST00000122116.1
ENSMUST00000120267.1
Atg16l2

autophagy related 16-like 2 (S. cerevisiae)

chr5_+_137030275 1.231 ENSMUST00000041543.8
Vgf
VGF nerve growth factor inducible
chr7_-_19629355 1.223 ENSMUST00000049912.8
ENSMUST00000094762.3
ENSMUST00000098754.4
Relb


avian reticuloendotheliosis viral (v-rel) oncogene related B


chr12_+_36314160 1.221 ENSMUST00000041407.5
Sostdc1
sclerostin domain containing 1
chr15_+_101266839 1.189 ENSMUST00000023779.6
Nr4a1
nuclear receptor subfamily 4, group A, member 1
chr3_+_117575268 1.160 ENSMUST00000039564.6
4833424O15Rik
RIKEN cDNA 4833424O15 gene
chr11_+_97799772 1.127 ENSMUST00000129558.1
Lasp1
LIM and SH3 protein 1
chr17_-_83631892 1.123 ENSMUST00000051482.1
Kcng3
potassium voltage-gated channel, subfamily G, member 3
chr9_+_95857597 1.104 ENSMUST00000034980.7
Atr
ataxia telangiectasia and Rad3 related
chr7_-_4546567 1.097 ENSMUST00000065957.5
Syt5
synaptotagmin V
chr18_+_37742088 1.083 ENSMUST00000003599.6
Pcdhga9
protocadherin gamma subfamily A, 9
chr5_+_30232581 1.064 ENSMUST00000145167.1
Ept1
ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
chr10_-_95415283 1.063 ENSMUST00000119917.1
Socs2
suppressor of cytokine signaling 2
chr16_+_32914094 1.050 ENSMUST00000023491.6
ENSMUST00000170899.1
ENSMUST00000171118.1
ENSMUST00000170201.1
ENSMUST00000165616.1
ENSMUST00000135193.2
Lrch3





leucine-rich repeats and calponin homology (CH) domain containing 3





chr3_+_7612702 1.046 ENSMUST00000181286.1
Gm16685
predicted gene, 16685
chr7_+_27653906 1.041 ENSMUST00000008088.7
Ttc9b
tetratricopeptide repeat domain 9B
chr12_-_55492587 1.036 ENSMUST00000021413.7
Nfkbia
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
chr4_-_40239700 1.024 ENSMUST00000142055.1
Ddx58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr7_+_28766747 1.019 ENSMUST00000170068.1
ENSMUST00000072965.4
Sirt2

sirtuin 2

chr11_+_97798995 1.000 ENSMUST00000143571.1
Lasp1
LIM and SH3 protein 1
chr10_+_127380799 0.998 ENSMUST00000111628.2
R3hdm2
R3H domain containing 2
chr18_+_38993126 0.989 ENSMUST00000097593.2
Arhgap26
Rho GTPase activating protein 26
chr4_+_114680769 0.989 ENSMUST00000146346.1
Gm12829
predicted gene 12829
chr14_+_55561060 0.977 ENSMUST00000117701.1
Dcaf11
DDB1 and CUL4 associated factor 11
chr10_+_127195240 0.956 ENSMUST00000181578.1
F420014N23Rik
RIKEN cDNA F420014N23 gene
chr1_-_155972887 0.953 ENSMUST00000138762.1
ENSMUST00000124495.1
Cep350

centrosomal protein 350

chr1_-_172590463 0.952 ENSMUST00000065679.6
Slamf8
SLAM family member 8
chr7_+_27605797 0.915 ENSMUST00000143499.1
ENSMUST00000108343.1
Akt2

thymoma viral proto-oncogene 2

chr15_-_89170688 0.901 ENSMUST00000060808.9
Plxnb2
plexin B2
chr7_+_27605847 0.898 ENSMUST00000051356.5
Akt2
thymoma viral proto-oncogene 2
chr17_+_35439155 0.894 ENSMUST00000071951.6
ENSMUST00000078205.7
ENSMUST00000116598.3
ENSMUST00000076256.7
H2-Q7



histocompatibility 2, Q region locus 7



chr2_+_16356294 0.852 ENSMUST00000028081.6
Plxdc2
plexin domain containing 2
chr6_-_122820606 0.844 ENSMUST00000181317.1
Gm26826
predicted gene, 26826
chr2_-_45113216 0.821 ENSMUST00000124942.1
Zeb2
zinc finger E-box binding homeobox 2
chr13_+_43785107 0.801 ENSMUST00000015540.2
Cd83
CD83 antigen
chr17_+_35379608 0.773 ENSMUST00000081435.4
H2-Q4
histocompatibility 2, Q region locus 4
chr11_+_78188806 0.754 ENSMUST00000056241.5
Rab34
RAB34, member of RAS oncogene family
chr6_+_55336424 0.699 ENSMUST00000004774.3
Aqp1
aquaporin 1
chr14_-_45529964 0.689 ENSMUST00000150660.1
Fermt2
fermitin family homolog 2 (Drosophila)
chr16_+_97997313 0.674 ENSMUST00000122450.1
B230307C23Rik
RIKEN cDNA B230307C23 gene
chr2_-_104816696 0.658 ENSMUST00000117237.1
Qser1
glutamine and serine rich 1
chr9_+_55326913 0.652 ENSMUST00000085754.3
ENSMUST00000034862.4
AI118078

expressed sequence AI118078

chr10_+_119992916 0.640 ENSMUST00000105261.2
Grip1
glutamate receptor interacting protein 1
chr7_-_57387172 0.627 ENSMUST00000068911.6
Gabrg3
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3
chr13_+_44730726 0.625 ENSMUST00000173704.1
ENSMUST00000044608.7
ENSMUST00000173367.1
Jarid2


jumonji, AT rich interactive domain 2


chr10_-_19015347 0.577 ENSMUST00000019997.4
Tnfaip3
tumor necrosis factor, alpha-induced protein 3
chr16_-_28929658 0.565 ENSMUST00000100023.1
Mb21d2
Mab-21 domain containing 2
chr19_-_5845471 0.543 ENSMUST00000174287.1
ENSMUST00000173672.1
Neat1

nuclear paraspeckle assembly transcript 1 (non-protein coding)

chr17_+_26933070 0.525 ENSMUST00000073724.5
Phf1
PHD finger protein 1
chr2_+_118900377 0.524 ENSMUST00000151162.1
Bahd1
bromo adjacent homology domain containing 1
chr2_+_16356744 0.519 ENSMUST00000114703.3
Plxdc2
plexin domain containing 2
chr9_-_41157459 0.518 ENSMUST00000136530.1
Ubash3b
ubiquitin associated and SH3 domain containing, B
chr16_-_3907651 0.517 ENSMUST00000177221.1
ENSMUST00000177323.1
1700037C18Rik

RIKEN cDNA 1700037C18 gene

chr4_-_108406676 0.514 ENSMUST00000184609.1
Gpx7
glutathione peroxidase 7
chr1_+_135132693 0.513 ENSMUST00000049449.4
Ptpn7
protein tyrosine phosphatase, non-receptor type 7
chr12_+_87026564 0.512 ENSMUST00000110187.1
ENSMUST00000156162.1
Tmem63c

transmembrane protein 63c

chr14_+_53324632 0.508 ENSMUST00000178100.1
Trav7n-6
T cell receptor alpha variable 7N-6
chr11_+_51263114 0.501 ENSMUST00000093132.6
ENSMUST00000109113.1
Clk4

CDC like kinase 4

chr2_+_29869484 0.497 ENSMUST00000047521.6
ENSMUST00000134152.1
Cercam

cerebral endothelial cell adhesion molecule

chr10_+_127380591 0.486 ENSMUST00000166820.1
R3hdm2
R3H domain containing 2
chr12_-_27160311 0.484 ENSMUST00000182473.1
ENSMUST00000177636.1
ENSMUST00000183238.1
Gm9866


predicted gene 9866


chr5_-_121502980 0.481 ENSMUST00000079368.3
Adam1b
a disintegrin and metallopeptidase domain 1b
chr7_+_80186835 0.474 ENSMUST00000107383.1
ENSMUST00000032754.7
Sema4b

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B

chr11_+_62077018 0.471 ENSMUST00000092415.5
Specc1
sperm antigen with calponin homology and coiled-coil domains 1
chr10_+_80755196 0.466 ENSMUST00000105336.2
Dot1l
DOT1-like, histone H3 methyltransferase (S. cerevisiae)
chr9_-_44735189 0.464 ENSMUST00000034611.8
Phldb1
pleckstrin homology-like domain, family B, member 1
chr2_+_61578549 0.458 ENSMUST00000112502.1
ENSMUST00000078074.2
Tank

TRAF family member-associated Nf-kappa B activator

chr11_+_101176041 0.452 ENSMUST00000103109.3
Cntnap1
contactin associated protein-like 1
chr17_+_35424842 0.429 ENSMUST00000174699.1
H2-Q6
histocompatibility 2, Q region locus 6
chr7_+_25681158 0.420 ENSMUST00000108403.3
B9d2
B9 protein domain 2
chr11_-_77078404 0.417 ENSMUST00000102494.1
Ccdc55
coiled-coil domain containing 55
chr11_+_70657196 0.369 ENSMUST00000157027.1
ENSMUST00000072841.5
ENSMUST00000108548.1
ENSMUST00000126241.1
Eno3



enolase 3, beta muscle



chrX_-_155216338 0.357 ENSMUST00000112551.3
Sat1
spermidine/spermine N1-acetyl transferase 1
chr13_-_113663670 0.346 ENSMUST00000054650.4
Hspb3
heat shock protein 3
chr2_+_177508570 0.339 ENSMUST00000108940.2
Gm14403
predicted gene 14403
chr5_-_144965793 0.298 ENSMUST00000110677.1
ENSMUST00000085684.4
ENSMUST00000100461.2
Smurf1


SMAD specific E3 ubiquitin protein ligase 1


chr4_-_49597425 0.279 ENSMUST00000150664.1
Tmem246
transmembrane protein 246
chr7_-_126200413 0.264 ENSMUST00000163959.1
Xpo6
exportin 6
chr4_-_43558386 0.243 ENSMUST00000130353.1
Tln1
talin 1
chr7_-_28766469 0.235 ENSMUST00000085851.5
ENSMUST00000032815.4
Nfkbib

nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta

chr2_-_27027909 0.234 ENSMUST00000102890.4
ENSMUST00000153388.1
ENSMUST00000045702.5
Slc2a6


solute carrier family 2 (facilitated glucose transporter), member 6


chr2_+_25500750 0.222 ENSMUST00000015239.3
Fbxw5
F-box and WD-40 domain protein 5
chr7_-_99626936 0.204 ENSMUST00000178124.1
Gm4980
predicted gene 4980
chr7_-_126200397 0.183 ENSMUST00000009344.9
Xpo6
exportin 6
chr16_-_55838827 0.171 ENSMUST00000096026.2
ENSMUST00000036273.6
ENSMUST00000114457.1
Nfkbiz


nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta


chr7_+_12977834 0.137 ENSMUST00000108537.1
ENSMUST00000108535.1
ENSMUST00000045810.7
Zfp446


zinc finger protein 446


chr11_-_101302206 0.074 ENSMUST00000140706.1
ENSMUST00000170502.1
ENSMUST00000172233.1
ENSMUST00000130916.1
Becn1



beclin 1, autophagy related



chr17_+_74717743 0.074 ENSMUST00000024882.6
Ttc27
tetratricopeptide repeat domain 27
chr18_-_34651703 0.071 ENSMUST00000025228.5
ENSMUST00000133181.1
Cdc23

CDC23 cell division cycle 23

chr12_-_28635914 0.062 ENSMUST00000074267.3
Rps7
ribosomal protein S7
chr4_+_155562348 0.046 ENSMUST00000030939.7
Nadk
NAD kinase
chr17_+_21691860 0.042 ENSMUST00000072133.4
Gm10226
predicted gene 10226
chr3_-_65958236 0.016 ENSMUST00000029416.7
Ccnl1
cyclin L1
chr5_-_66451629 0.010 ENSMUST00000160063.1
Apbb2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr4_+_126262325 0.010 ENSMUST00000030660.8
Trappc3
trafficking protein particle complex 3
chr5_+_86804508 0.007 ENSMUST00000038384.7
Ythdc1
YTH domain containing 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 9.3 GO:0002158 osteoclast proliferation(GO:0002158)
1.6 8.2 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
1.3 7.6 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
1.2 4.9 GO:0001920 negative regulation of receptor recycling(GO:0001920)
1.0 3.1 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.8 3.0 GO:0009597 detection of virus(GO:0009597)
0.7 2.2 GO:0070944 neutrophil mediated killing of bacterium(GO:0070944)
0.7 2.8 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.5 1.6 GO:0032916 positive regulation of transforming growth factor beta3 production(GO:0032916)
0.5 2.1 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.5 2.6 GO:1905169 protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171)
0.5 1.5 GO:0001827 inner cell mass cell fate commitment(GO:0001827)
0.5 1.8 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
0.4 1.3 GO:0021998 neural plate mediolateral regionalization(GO:0021998) mesoderm structural organization(GO:0048338) paraxial mesoderm structural organization(GO:0048352) positive regulation of cardiac ventricle development(GO:1904414)
0.4 1.2 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.4 1.1 GO:1904884 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.3 0.7 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.3 2.1 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.3 1.7 GO:0032329 serine transport(GO:0032329)
0.3 1.0 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.3 1.6 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.3 1.8 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.3 0.3 GO:1902534 single-organism membrane invagination(GO:1902534)
0.3 1.3 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.2 1.0 GO:2000508 regulation of dendritic cell chemotaxis(GO:2000508)
0.2 1.6 GO:0016584 nucleosome positioning(GO:0016584)
0.2 2.7 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.2 1.2 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.2 1.4 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.2 3.2 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.1 1.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 1.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 6.6 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 1.8 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 0.8 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.1 0.4 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 0.5 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.1 0.5 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.5 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 2.9 GO:0043496 regulation of protein homodimerization activity(GO:0043496)
0.1 2.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.5 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 1.2 GO:0043084 penile erection(GO:0043084)
0.1 1.2 GO:0043011 negative regulation of interferon-beta production(GO:0032688) myeloid dendritic cell differentiation(GO:0043011)
0.1 4.6 GO:0021766 hippocampus development(GO:0021766)
0.1 1.0 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.6 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.2 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.5 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 1.6 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.2 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.5 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.0 0.5 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 1.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 3.5 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 4.8 GO:0007416 synapse assembly(GO:0007416)
0.0 1.3 GO:1901998 toxin transport(GO:1901998)
0.0 0.9 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.6 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.5 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.2 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.4 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.1 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.0 0.7 GO:0048041 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.7 2.2 GO:0071953 elastic fiber(GO:0071953)
0.6 1.8 GO:0000802 transverse filament(GO:0000802)
0.5 7.6 GO:0031143 pseudopodium(GO:0031143)
0.5 6.6 GO:0042581 specific granule(GO:0042581)
0.3 3.1 GO:1990909 Wnt signalosome(GO:1990909)
0.3 1.1 GO:1990769 proximal neuron projection(GO:1990769)
0.2 0.7 GO:0032127 dense core granule membrane(GO:0032127)
0.2 4.8 GO:0005605 basal lamina(GO:0005605)
0.2 2.1 GO:0043083 synaptic cleft(GO:0043083)
0.2 1.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.2 1.0 GO:0033010 paranodal junction(GO:0033010)
0.2 1.3 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 2.8 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 1.6 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 1.8 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 4.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 0.5 GO:0042382 paraspeckles(GO:0042382)
0.1 4.2 GO:0030667 secretory granule membrane(GO:0030667)
0.1 1.2 GO:0000421 autophagosome membrane(GO:0000421)
0.1 2.0 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 2.6 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 1.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.5 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 1.1 GO:0001741 XY body(GO:0001741)
0.0 0.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 1.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.5 GO:0045180 basal cortex(GO:0045180)
0.0 2.4 GO:0005604 basement membrane(GO:0005604)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 0.5 GO:0033270 paranode region of axon(GO:0033270)
0.0 3.0 GO:0005923 bicellular tight junction(GO:0005923)
0.0 1.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.7 GO:0031941 filamentous actin(GO:0031941)
0.0 1.3 GO:0005901 caveola(GO:0005901)
0.0 0.6 GO:0034707 chloride channel complex(GO:0034707)
0.0 3.2 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.7 GO:0001650 fibrillar center(GO:0001650)
0.0 1.5 GO:0034399 nuclear periphery(GO:0034399)
0.0 1.5 GO:0001726 ruffle(GO:0001726)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.6 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.7 6.6 GO:0036122 BMP binding(GO:0036122)
0.6 3.2 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.5 4.9 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.5 1.6 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.3 1.3 GO:0098821 BMP receptor activity(GO:0098821)
0.3 2.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.3 1.0 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739) tubulin deacetylase activity(GO:0042903)
0.3 4.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 1.7 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.2 1.1 GO:0032405 MutLalpha complex binding(GO:0032405) MutSalpha complex binding(GO:0032407)
0.2 3.1 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.2 1.7 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.7 GO:0015166 polyol transmembrane transporter activity(GO:0015166) glycerol transmembrane transporter activity(GO:0015168)
0.1 1.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.5 GO:0004096 catalase activity(GO:0004096)
0.1 1.6 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 0.4 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.1 0.5 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 2.3 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 0.6 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 2.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 2.8 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 2.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 2.4 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.9 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 1.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 1.9 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 1.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 3.9 GO:0005125 cytokine activity(GO:0005125)
0.0 3.0 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 1.0 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.5 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 1.3 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 1.5 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.6 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 1.8 GO:0005080 protein kinase C binding(GO:0005080)
0.0 8.6 GO:0045296 cadherin binding(GO:0045296)
0.0 0.7 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.5 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.6 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.5 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.4 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.2 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 2.2 GO:0042393 histone binding(GO:0042393)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 8.2 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.4 3.9 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 7.6 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.2 11.4 PID_BMP_PATHWAY BMP receptor signaling
0.1 4.6 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.1 3.6 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.1 1.6 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.1 1.3 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.1 1.8 SA_TRKA_RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 1.5 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.1 2.8 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 1.1 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.1 0.5 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 3.2 PID_IL2_1PATHWAY IL2-mediated signaling events
0.1 2.1 PID_REELIN_PATHWAY Reelin signaling pathway
0.0 5.1 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.0 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 1.2 PID_IL12_2PATHWAY IL12-mediated signaling events
0.0 1.2 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.2 PID_NFAT_3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.6 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.2 7.6 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.2 1.4 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 3.0 REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 3.7 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 1.0 REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 1.8 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.1 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 2.8 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 3.2 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.1 0.7 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.7 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 5.1 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 1.6 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 1.5 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 1.8 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.2 REACTOME_PIP3_ACTIVATES_AKT_SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.6 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.0 0.5 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 1.6 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.7 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.6 REACTOME_NOD1_2_SIGNALING_PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.2 REACTOME_TAK1_ACTIVATES_NFKB_BY_PHOSPHORYLATION_AND_ACTIVATION_OF_IKKS_COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 0.4 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.2 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.9 REACTOME_ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS Genes involved in Activation of NF-kappaB in B Cells