Motif ID: Tlx1

Z-value: 0.637


Transcription factors associated with Tlx1:

Gene SymbolEntrez IDGene Name
Tlx1 ENSMUSG00000025215.9 Tlx1



Activity profile for motif Tlx1.

activity profile for motif Tlx1


Sorted Z-values histogram for motif Tlx1

Sorted Z-values for motif Tlx1



Network of associatons between targets according to the STRING database.



First level regulatory network of Tlx1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_97450136 3.427 ENSMUST00000107601.1
Arhgap23
Rho GTPase activating protein 23
chr2_+_82053222 2.406 ENSMUST00000047527.7
Zfp804a
zinc finger protein 804A
chr8_-_109251698 2.167 ENSMUST00000079189.3
4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr3_+_156562141 1.949 ENSMUST00000175773.1
Negr1
neuronal growth regulator 1
chr6_+_54681687 1.888 ENSMUST00000046276.6
2410066E13Rik
RIKEN cDNA 2410066E13 gene
chr8_-_57962564 1.884 ENSMUST00000098757.3
Galntl6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
chr4_+_48045144 1.770 ENSMUST00000030025.3
Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr4_-_136956784 1.750 ENSMUST00000030420.8
Epha8
Eph receptor A8
chr12_-_78983476 1.748 ENSMUST00000070174.7
Tmem229b
transmembrane protein 229B
chr2_+_120629113 1.713 ENSMUST00000150912.1
ENSMUST00000180041.1
Stard9

START domain containing 9

chr19_-_5924797 1.685 ENSMUST00000055458.4
Cdc42ep2
CDC42 effector protein (Rho GTPase binding) 2
chr2_+_118663235 1.671 ENSMUST00000099557.3
Pak6
p21 protein (Cdc42/Rac)-activated kinase 6
chr7_-_4844665 1.670 ENSMUST00000066041.5
ENSMUST00000172377.1
Shisa7

shisa homolog 7 (Xenopus laevis)

chr1_-_75278345 1.668 ENSMUST00000039534.4
Resp18
regulated endocrine-specific protein 18
chr3_+_123267445 1.641 ENSMUST00000047923.7
Sec24d
Sec24 related gene family, member D (S. cerevisiae)
chrX_-_73880831 1.617 ENSMUST00000102871.3
L1cam
L1 cell adhesion molecule
chr11_-_116654245 1.613 ENSMUST00000021166.5
Cygb
cytoglobin
chr8_+_84415348 1.526 ENSMUST00000121390.1
ENSMUST00000122053.1
Cacna1a

calcium channel, voltage-dependent, P/Q type, alpha 1A subunit

chr9_+_21165714 1.490 ENSMUST00000039413.8
Pde4a
phosphodiesterase 4A, cAMP specific
chr12_+_95692212 1.436 ENSMUST00000057324.3
Flrt2
fibronectin leucine rich transmembrane protein 2
chr3_-_104511812 1.366 ENSMUST00000046316.6
Lrig2
leucine-rich repeats and immunoglobulin-like domains 2
chr10_+_69785507 1.341 ENSMUST00000182993.1
Ank3
ankyrin 3, epithelial
chr1_-_79440039 1.339 ENSMUST00000049972.4
Scg2
secretogranin II
chr7_+_29309429 1.328 ENSMUST00000137848.1
Dpf1
D4, zinc and double PHD fingers family 1
chr2_-_26257554 1.305 ENSMUST00000137586.2
C030048H21Rik
RIKEN cDNA C030048H21 gene
chr17_+_8340710 1.293 ENSMUST00000163887.1
Prr18
proline rich region 18
chr13_+_16011851 1.210 ENSMUST00000042603.6
Inhba
inhibin beta-A
chr4_+_136284658 1.169 ENSMUST00000144217.1
Zfp46
zinc finger protein 46
chr5_-_67815852 1.153 ENSMUST00000141443.1
Atp8a1
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
chr9_+_104566677 1.146 ENSMUST00000157006.1
Cpne4
copine IV
chr18_+_33464163 1.132 ENSMUST00000097634.3
Gm10549
predicted gene 10549
chr9_+_76014855 1.119 ENSMUST00000008052.6
ENSMUST00000183425.1
ENSMUST00000183979.1
ENSMUST00000117981.2
Hmgcll1



3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase-like 1



chr9_+_109931774 1.117 ENSMUST00000169851.2
Map4
microtubule-associated protein 4
chr2_-_104257400 1.077 ENSMUST00000141159.1
D430041D05Rik
RIKEN cDNA D430041D05 gene
chr11_+_43682038 1.068 ENSMUST00000094294.4
Pwwp2a
PWWP domain containing 2A
chr8_-_94876269 1.054 ENSMUST00000046461.7
Dok4
docking protein 4
chr1_-_37536232 1.045 ENSMUST00000042161.8
Mgat4a
mannoside acetylglucosaminyltransferase 4, isoenzyme A
chr11_-_89060697 1.038 ENSMUST00000000285.2
Dgke
diacylglycerol kinase, epsilon
chr1_-_162859919 1.028 ENSMUST00000134098.1
ENSMUST00000111518.1
Fmo1

flavin containing monooxygenase 1

chr8_-_40511298 1.019 ENSMUST00000149992.1
Cnot7
CCR4-NOT transcription complex, subunit 7
chr12_+_71048338 1.009 ENSMUST00000135709.1
Arid4a
AT rich interactive domain 4A (RBP1-like)
chr4_+_136284708 1.009 ENSMUST00000130223.1
Zfp46
zinc finger protein 46
chr5_-_66451629 0.944 ENSMUST00000160063.1
Apbb2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr2_-_150451486 0.939 ENSMUST00000109916.1
Zfp442
zinc finger protein 442
chr9_+_65265173 0.939 ENSMUST00000048762.1
Cilp
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr1_+_136131382 0.927 ENSMUST00000075164.4
Kif21b
kinesin family member 21B
chr6_-_56362356 0.912 ENSMUST00000044505.7
ENSMUST00000166102.1
ENSMUST00000164037.1
ENSMUST00000114327.2
Pde1c



phosphodiesterase 1C



chr3_-_63964659 0.903 ENSMUST00000161659.1
Slc33a1
solute carrier family 33 (acetyl-CoA transporter), member 1
chr16_-_17144415 0.891 ENSMUST00000115709.1
Ccdc116
coiled-coil domain containing 116
chr18_+_86711520 0.887 ENSMUST00000122464.1
Cbln2
cerebellin 2 precursor protein
chr10_-_62340514 0.881 ENSMUST00000099691.4
Hk1
hexokinase 1
chr1_-_126830632 0.862 ENSMUST00000112583.1
ENSMUST00000094609.3
Nckap5

NCK-associated protein 5

chrX_+_94234921 0.856 ENSMUST00000113908.1
ENSMUST00000113916.3
Klhl15

kelch-like 15

chr10_+_86302854 0.856 ENSMUST00000132307.1
Timp3
tissue inhibitor of metalloproteinase 3
chr2_+_178193075 0.847 ENSMUST00000103065.1
Phactr3
phosphatase and actin regulator 3
chr1_-_87573825 0.846 ENSMUST00000068681.5
Ngef
neuronal guanine nucleotide exchange factor
chr6_+_4903350 0.833 ENSMUST00000175962.1
Ppp1r9a
protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr11_+_97798995 0.828 ENSMUST00000143571.1
Lasp1
LIM and SH3 protein 1
chr3_-_107931817 0.826 ENSMUST00000004137.4
Gstm7
glutathione S-transferase, mu 7
chrX_+_94234594 0.818 ENSMUST00000153900.1
Klhl15
kelch-like 15
chr3_-_107931579 0.792 ENSMUST00000133947.2
ENSMUST00000124215.1
ENSMUST00000106688.1
ENSMUST00000106687.2
Gstm7



glutathione S-transferase, mu 7



chr7_+_113765998 0.790 ENSMUST00000046687.9
Spon1
spondin 1, (f-spondin) extracellular matrix protein
chr1_-_37865040 0.788 ENSMUST00000041815.8
Tsga10
testis specific 10
chr5_+_104775911 0.787 ENSMUST00000055593.7
Gm8258
predicted gene 8258
chr6_+_55452177 0.785 ENSMUST00000167484.1
Adcyap1r1
adenylate cyclase activating polypeptide 1 receptor 1
chr2_+_22895583 0.774 ENSMUST00000152170.1
Pdss1
prenyl (solanesyl) diphosphate synthase, subunit 1
chr17_+_6106880 0.773 ENSMUST00000149756.1
Tulp4
tubby like protein 4
chr7_+_28180272 0.773 ENSMUST00000173223.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr3_+_97658212 0.772 ENSMUST00000045743.6
Prkab2
protein kinase, AMP-activated, beta 2 non-catalytic subunit
chr7_+_92819892 0.758 ENSMUST00000107180.1
ENSMUST00000107179.1
Rab30

RAB30, member RAS oncogene family

chr11_+_43681998 0.754 ENSMUST00000061070.5
Pwwp2a
PWWP domain containing 2A
chr18_+_86711059 0.749 ENSMUST00000068423.3
Cbln2
cerebellin 2 precursor protein
chr6_+_4601124 0.746 ENSMUST00000181734.1
ENSMUST00000141359.1
Casd1

CAS1 domain containing 1

chr1_+_172481788 0.745 ENSMUST00000127052.1
Igsf9
immunoglobulin superfamily, member 9
chr5_+_90759299 0.745 ENSMUST00000031318.4
Cxcl5
chemokine (C-X-C motif) ligand 5
chr16_+_20696175 0.742 ENSMUST00000128273.1
Fam131a
family with sequence similarity 131, member A
chr3_+_107036156 0.736 ENSMUST00000052718.3
Kcna3
potassium voltage-gated channel, shaker-related subfamily, member 3
chr6_+_4903298 0.718 ENSMUST00000035813.2
Ppp1r9a
protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr7_+_123123870 0.714 ENSMUST00000094053.5
Tnrc6a
trinucleotide repeat containing 6a
chr19_-_5098418 0.713 ENSMUST00000025805.6
Cnih2
cornichon homolog 2 (Drosophila)
chr8_-_40511663 0.709 ENSMUST00000135269.1
ENSMUST00000034012.3
Cnot7

CCR4-NOT transcription complex, subunit 7

chr2_-_150136641 0.706 ENSMUST00000094538.5
ENSMUST00000109931.1
ENSMUST00000089207.6
Zfp120


zinc finger protein 120


chr19_+_5447692 0.705 ENSMUST00000025850.5
Fosl1
fos-like antigen 1
chr1_-_56969864 0.701 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr2_-_168734236 0.698 ENSMUST00000109175.2
Atp9a
ATPase, class II, type 9A
chr4_-_35225789 0.694 ENSMUST00000108126.1
ENSMUST00000108127.3
3110043O21Rik

RIKEN cDNA 3110043O21 gene

chr16_-_48993931 0.692 ENSMUST00000114516.1
Dzip3
DAZ interacting protein 3, zinc finger
chr3_-_85746266 0.690 ENSMUST00000118408.1
Fam160a1
family with sequence similarity 160, member A1
chr3_+_96601084 0.690 ENSMUST00000062058.3
Lix1l
Lix1-like
chr4_-_147848358 0.685 ENSMUST00000105718.1
ENSMUST00000135798.1
Zfp933

zinc finger protein 933

chr3_-_94658800 0.679 ENSMUST00000107277.1
ENSMUST00000006123.4
ENSMUST00000107279.2
Tuft1


tuftelin 1


chr5_-_131538687 0.675 ENSMUST00000161374.1
Auts2
autism susceptibility candidate 2
chr5_-_116288944 0.674 ENSMUST00000086483.3
Ccdc60
coiled-coil domain containing 60
chr6_-_113501818 0.639 ENSMUST00000101059.1
Prrt3
proline-rich transmembrane protein 3
chr17_+_32621319 0.630 ENSMUST00000077639.5
Gm9705
predicted gene 9705
chr1_-_88277470 0.628 ENSMUST00000147393.1
Hjurp
Holliday junction recognition protein
chr1_+_133246092 0.627 ENSMUST00000038295.8
ENSMUST00000105082.2
Plekha6

pleckstrin homology domain containing, family A member 6

chr3_+_88616133 0.625 ENSMUST00000176500.1
ENSMUST00000177498.1
Arhgef2

rho/rac guanine nucleotide exchange factor (GEF) 2

chr5_-_24329556 0.618 ENSMUST00000115098.2
Kcnh2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr12_-_112511136 0.610 ENSMUST00000066791.5
Tmem179
transmembrane protein 179
chr1_-_25829511 0.597 ENSMUST00000135518.1
ENSMUST00000151309.1
Bai3

brain-specific angiogenesis inhibitor 3

chr2_+_30982279 0.597 ENSMUST00000102849.4
Usp20
ubiquitin specific peptidase 20
chr19_+_16956110 0.590 ENSMUST00000087689.4
Prune2
prune homolog 2 (Drosophila)
chr13_-_98815408 0.583 ENSMUST00000040340.8
ENSMUST00000099277.4
ENSMUST00000179563.1
ENSMUST00000109403.1
Fcho2



FCH domain only 2



chr7_+_28180226 0.565 ENSMUST00000172467.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr5_-_122050102 0.565 ENSMUST00000154139.1
Cux2
cut-like homeobox 2
chr11_+_97050811 0.563 ENSMUST00000168565.1
Osbpl7
oxysterol binding protein-like 7
chr16_-_76373827 0.561 ENSMUST00000121927.1
Nrip1
nuclear receptor interacting protein 1
chr1_+_139422196 0.558 ENSMUST00000039867.7
Zbtb41
zinc finger and BTB domain containing 41 homolog
chr2_-_150362708 0.556 ENSMUST00000051153.5
3300002I08Rik
RIKEN cDNA 3300002I08 gene
chr14_-_63177793 0.555 ENSMUST00000054963.9
Fdft1
farnesyl diphosphate farnesyl transferase 1
chr11_-_5741141 0.548 ENSMUST00000140922.1
ENSMUST00000093362.5
Urgcp

upregulator of cell proliferation

chr2_-_167060417 0.547 ENSMUST00000155281.1
Znfx1
zinc finger, NFX1-type containing 1
chr17_+_31296191 0.537 ENSMUST00000165149.1
Slc37a1
solute carrier family 37 (glycerol-3-phosphate transporter), member 1
chr13_-_41847626 0.522 ENSMUST00000121404.1
Adtrp
androgen dependent TFPI regulating protein
chr11_+_3989924 0.519 ENSMUST00000109981.1
Gal3st1
galactose-3-O-sulfotransferase 1
chr11_+_97050594 0.516 ENSMUST00000090020.5
Osbpl7
oxysterol binding protein-like 7
chr4_-_42856771 0.515 ENSMUST00000107981.1
Gm12394
predicted gene 12394
chr4_-_155992604 0.509 ENSMUST00000052185.3
B3galt6
UDP-Gal:betaGal beta 1,3-galactosyltransferase, polypeptide 6
chr7_+_25152456 0.509 ENSMUST00000098678.1
D930028M14Rik
RIKEN cDNA D930028M14 gene
chr19_-_5085483 0.507 ENSMUST00000140389.1
ENSMUST00000151413.1
ENSMUST00000077066.7
Tmem151a


transmembrane protein 151A


chr2_-_114052804 0.506 ENSMUST00000090269.6
Actc1
actin, alpha, cardiac muscle 1
chr2_+_49787675 0.506 ENSMUST00000028103.6
Lypd6b
LY6/PLAUR domain containing 6B
chrX_+_94234982 0.498 ENSMUST00000096369.3
ENSMUST00000113911.2
Klhl15

kelch-like 15

chr9_-_15301555 0.485 ENSMUST00000034414.8
4931406C07Rik
RIKEN cDNA 4931406C07 gene
chr11_-_64436653 0.483 ENSMUST00000177999.1
F930015N05Rik
RIKEN cDNA F930015N05 gene
chr3_+_89715016 0.482 ENSMUST00000098924.2
Adar
adenosine deaminase, RNA-specific
chr3_-_63964768 0.480 ENSMUST00000029402.8
Slc33a1
solute carrier family 33 (acetyl-CoA transporter), member 1
chr11_-_97775876 0.478 ENSMUST00000107576.1
1700001P01Rik
RIKEN cDNA 1700001P01 gene
chr4_-_140617062 0.478 ENSMUST00000154979.1
Arhgef10l
Rho guanine nucleotide exchange factor (GEF) 10-like
chr14_+_8002949 0.475 ENSMUST00000026313.3
Abhd6
abhydrolase domain containing 6
chr1_-_88277510 0.471 ENSMUST00000065420.5
ENSMUST00000054674.8
Hjurp

Holliday junction recognition protein

chr4_+_59581645 0.467 ENSMUST00000107528.1
Hsdl2
hydroxysteroid dehydrogenase like 2
chr9_-_99436687 0.464 ENSMUST00000035045.8
Mras
muscle and microspikes RAS
chrX_+_109095359 0.459 ENSMUST00000033598.8
Sh3bgrl
SH3-binding domain glutamic acid-rich protein like
chr9_+_78109188 0.459 ENSMUST00000118869.1
ENSMUST00000125615.1
Ick

intestinal cell kinase

chr2_+_135659625 0.458 ENSMUST00000134310.1
Plcb4
phospholipase C, beta 4
chr13_-_41847482 0.455 ENSMUST00000072012.3
Adtrp
androgen dependent TFPI regulating protein
chr1_-_126830786 0.448 ENSMUST00000162646.1
Nckap5
NCK-associated protein 5
chr6_-_115251839 0.447 ENSMUST00000032462.6
Timp4
tissue inhibitor of metalloproteinase 4
chr3_-_151749877 0.444 ENSMUST00000029671.7
Ifi44
interferon-induced protein 44
chr17_-_25919506 0.439 ENSMUST00000164982.1
ENSMUST00000179998.1
ENSMUST00000167626.1
ENSMUST00000164738.1
ENSMUST00000026826.7
ENSMUST00000167018.1
Rab40c





Rab40c, member RAS oncogene family





chr10_+_112928501 0.439 ENSMUST00000180464.1
Gm26596
predicted gene, 26596
chr12_-_84148449 0.438 ENSMUST00000061425.2
Pnma1
paraneoplastic antigen MA1
chr9_+_44773027 0.426 ENSMUST00000125877.1
Ift46
intraflagellar transport 46
chrX_+_151046131 0.418 ENSMUST00000112685.1
Fgd1
FYVE, RhoGEF and PH domain containing 1
chr14_+_8002890 0.418 ENSMUST00000166497.1
Abhd6
abhydrolase domain containing 6
chr9_-_99436749 0.410 ENSMUST00000122384.1
Mras
muscle and microspikes RAS
chr1_+_176814660 0.390 ENSMUST00000056773.8
ENSMUST00000027785.8
Sdccag8

serologically defined colon cancer antigen 8

chr11_+_3488275 0.388 ENSMUST00000064265.6
Pla2g3
phospholipase A2, group III
chr1_+_163929765 0.387 ENSMUST00000027876.4
ENSMUST00000170359.1
Scyl3

SCY1-like 3 (S. cerevisiae)

chr6_+_55451978 0.387 ENSMUST00000070736.5
ENSMUST00000070756.5
ENSMUST00000166962.1
Adcyap1r1


adenylate cyclase activating polypeptide 1 receptor 1


chr5_-_134314637 0.382 ENSMUST00000173504.1
Gtf2i
general transcription factor II I
chr10_+_96136603 0.380 ENSMUST00000074615.6
Gm5426
predicted pseudogene 5426
chr3_-_144760841 0.371 ENSMUST00000059091.5
Clca1
chloride channel calcium activated 1
chr14_+_54476100 0.367 ENSMUST00000164766.1
ENSMUST00000164697.1
Rem2

rad and gem related GTP binding protein 2

chr18_-_33464007 0.366 ENSMUST00000168890.1
Nrep
neuronal regeneration related protein
chr13_+_54949388 0.365 ENSMUST00000026994.7
ENSMUST00000109994.2
Unc5a

unc-5 homolog A (C. elegans)

chr7_-_134232005 0.353 ENSMUST00000134504.1
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr6_-_88518760 0.352 ENSMUST00000032168.5
Sec61a1
Sec61 alpha 1 subunit (S. cerevisiae)
chr11_-_19018714 0.349 ENSMUST00000177417.1
Meis1
Meis homeobox 1
chr9_-_53610329 0.349 ENSMUST00000034547.5
Acat1
acetyl-Coenzyme A acetyltransferase 1
chr6_+_147091379 0.345 ENSMUST00000036003.7
Klhl42
kelch-like 42
chr1_+_132007606 0.343 ENSMUST00000086556.5
Elk4
ELK4, member of ETS oncogene family
chr9_+_44773191 0.339 ENSMUST00000147559.1
Ift46
intraflagellar transport 46
chr13_+_43785107 0.339 ENSMUST00000015540.2
Cd83
CD83 antigen
chr19_+_4878671 0.334 ENSMUST00000006632.7
Zdhhc24
zinc finger, DHHC domain containing 24
chr16_-_18426372 0.330 ENSMUST00000000335.4
Comt
catechol-O-methyltransferase
chr9_+_50856924 0.328 ENSMUST00000174628.1
ENSMUST00000034560.7
ENSMUST00000114437.2
ENSMUST00000175645.1
ENSMUST00000176349.1
ENSMUST00000176798.1
ENSMUST00000175640.1
Ppp2r1b






protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform






chr18_-_61211380 0.324 ENSMUST00000148829.1
Slc26a2
solute carrier family 26 (sulfate transporter), member 2
chr14_-_30008817 0.315 ENSMUST00000122205.1
ENSMUST00000016110.6
Il17rb

interleukin 17 receptor B

chr5_+_34549568 0.307 ENSMUST00000118545.1
Sh3bp2
SH3-domain binding protein 2
chr4_+_59581563 0.307 ENSMUST00000030078.5
Hsdl2
hydroxysteroid dehydrogenase like 2
chr9_-_78108587 0.307 ENSMUST00000162625.1
ENSMUST00000159099.1
Fbxo9

f-box protein 9

chrX_+_20662898 0.306 ENSMUST00000001989.8
Uba1
ubiquitin-like modifier activating enzyme 1
chr2_+_22895482 0.296 ENSMUST00000053729.7
Pdss1
prenyl (solanesyl) diphosphate synthase, subunit 1
chr13_-_46727932 0.296 ENSMUST00000021803.9
Nup153
nucleoporin 153
chr5_-_134314378 0.295 ENSMUST00000174867.1
Gtf2i
general transcription factor II I
chr13_+_4191163 0.293 ENSMUST00000021634.2
Akr1c13
aldo-keto reductase family 1, member C13
chr19_+_8850785 0.292 ENSMUST00000096257.2
Lrrn4cl
LRRN4 C-terminal like
chr1_+_153652943 0.289 ENSMUST00000041776.5
Rgs8
regulator of G-protein signaling 8
chr16_-_48994081 0.287 ENSMUST00000121869.1
Dzip3
DAZ interacting protein 3, zinc finger
chr7_-_127890918 0.286 ENSMUST00000121394.1
Prss53
protease, serine, 53
chr6_-_85933379 0.286 ENSMUST00000162660.1
Nat8b
N-acetyltransferase 8B
chr1_+_49244616 0.286 ENSMUST00000056879.8
C230029F24Rik
RIKEN cDNA C230029F24 gene
chr17_-_25837082 0.281 ENSMUST00000183929.1
ENSMUST00000184865.1
ENSMUST00000026831.7
Rhbdl1


rhomboid, veinlet-like 1 (Drosophila)


chr6_-_24515036 0.277 ENSMUST00000052277.4
Iqub
IQ motif and ubiquitin domain containing
chr3_-_57847478 0.273 ENSMUST00000120289.1
ENSMUST00000066882.8
Pfn2

profilin 2

chr5_-_115194283 0.269 ENSMUST00000112113.1
Cabp1
calcium binding protein 1
chr2_-_155692317 0.266 ENSMUST00000103140.4
Trpc4ap
transient receptor potential cation channel, subfamily C, member 4 associated protein
chr2_+_149830894 0.264 ENSMUST00000137280.1
ENSMUST00000149705.1
Syndig1

synapse differentiation inducing 1

chr8_+_104831572 0.254 ENSMUST00000059449.6
Ces2b
carboxyesterase 2B
chr7_-_80403315 0.252 ENSMUST00000147150.1
Furin
furin (paired basic amino acid cleaving enzyme)
chr2_+_149830840 0.247 ENSMUST00000109934.1
ENSMUST00000140870.1
Syndig1

synapse differentiation inducing 1

chr9_+_107400043 0.244 ENSMUST00000166799.1
ENSMUST00000170737.1
Cacna2d2

calcium channel, voltage-dependent, alpha 2/delta subunit 2

chr14_+_51091077 0.244 ENSMUST00000022428.5
ENSMUST00000171688.1
Rnase4
Ang
ribonuclease, RNase A family 4
angiogenin, ribonuclease, RNase A family, 5
chr13_+_12565868 0.236 ENSMUST00000071973.6
Ero1lb
ERO1-like beta (S. cerevisiae)
chr5_-_84417359 0.234 ENSMUST00000113401.1
Epha5
Eph receptor A5
chr5_-_100719675 0.230 ENSMUST00000112908.1
ENSMUST00000045617.8
Hpse

heparanase

chr2_-_164833438 0.223 ENSMUST00000042775.4
Neurl2
neuralized-like 2 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0031335 regulation of sulfur amino acid metabolic process(GO:0031335)
0.6 1.8 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
0.5 1.6 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.4 2.5 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.4 1.6 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.4 2.2 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.3 1.6 GO:0015671 oxygen transport(GO:0015671)
0.3 3.2 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.3 2.2 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.3 1.5 GO:0046950 cellular ketone body metabolic process(GO:0046950)
0.3 1.3 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.2 0.7 GO:0070944 neutrophil mediated killing of bacterium(GO:0070944)
0.2 0.7 GO:1901608 regulation of vesicle transport along microtubule(GO:1901608)
0.2 0.7 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.2 1.1 GO:0051012 microtubule sliding(GO:0051012)
0.2 1.4 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.2 0.6 GO:0001543 ovarian follicle rupture(GO:0001543)
0.2 1.1 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.2 0.5 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.2 1.0 GO:0034773 histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.2 1.2 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.2 1.6 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.1 1.7 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.6 GO:0016128 phytosteroid metabolic process(GO:0016128) phytosteroid biosynthetic process(GO:0016129)
0.1 1.1 GO:0071397 cellular response to cholesterol(GO:0071397)
0.1 0.9 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.9 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.2 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.1 1.3 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.4 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 1.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 1.2 GO:0009404 toxin metabolic process(GO:0009404)
0.1 0.4 GO:0048820 hair follicle maturation(GO:0048820)
0.1 0.6 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.5 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.1 0.7 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.3 GO:0032240 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.1 1.2 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.1 0.4 GO:0019372 lipoxygenase pathway(GO:0019372)
0.1 0.5 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.1 0.4 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 0.8 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.1 1.7 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.2 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430)
0.1 0.9 GO:0010359 regulation of anion channel activity(GO:0010359)
0.1 0.2 GO:0030070 insulin processing(GO:0030070)
0.1 0.6 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 0.2 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.1 2.4 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 0.2 GO:0034035 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.1 0.3 GO:0090472 dibasic protein processing(GO:0090472)
0.1 1.1 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.1 0.5 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.3 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.1 0.2 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.1 0.3 GO:2000664 positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
0.1 0.4 GO:0048793 pronephros development(GO:0048793)
0.0 0.7 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 1.0 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.2 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 0.3 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.9 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.0 0.7 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.1 GO:0060279 positive regulation of ovulation(GO:0060279)
0.0 0.6 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.0 0.1 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.2 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.4 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 1.3 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.7 GO:0007614 short-term memory(GO:0007614)
0.0 0.5 GO:0008272 sulfate transport(GO:0008272)
0.0 0.1 GO:0032632 interleukin-3 production(GO:0032632)
0.0 0.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.1 GO:0070488 neutrophil aggregation(GO:0070488)
0.0 0.1 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.0 0.2 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.0 0.2 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.7 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.7 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.3 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.3 GO:0070932 histone H3 deacetylation(GO:0070932)
0.0 0.1 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.0 0.3 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.7 GO:1903432 regulation of TORC1 signaling(GO:1903432)
0.0 0.1 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.6 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.5 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 1.6 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.1 GO:0035826 rubidium ion transport(GO:0035826) cellular hypotonic response(GO:0071476)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.3 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0 0.8 GO:0061512 protein localization to cilium(GO:0061512)
0.0 1.7 GO:0051225 spindle assembly(GO:0051225)
0.0 0.1 GO:0035729 cellular response to hepatocyte growth factor stimulus(GO:0035729)
0.0 0.7 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.6 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.1 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 0.4 GO:0002437 inflammatory response to antigenic stimulus(GO:0002437)
0.0 1.7 GO:0007613 memory(GO:0007613)
0.0 0.2 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 2.9 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.9 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.7 GO:0050807 regulation of synapse organization(GO:0050807)
0.0 1.0 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.1 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0043512 inhibin A complex(GO:0043512)
0.3 1.7 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.3 1.6 GO:1990761 growth cone lamellipodium(GO:1990761)
0.3 1.7 GO:0042025 host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.2 0.6 GO:0098835 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.2 1.6 GO:0044294 dendritic growth cone(GO:0044294)
0.2 0.6 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 1.0 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 1.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.2 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 0.5 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.7 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 3.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.2 GO:0005927 muscle tendon junction(GO:0005927)
0.1 0.7 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.1 1.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 1.3 GO:0071565 nBAF complex(GO:0071565)
0.0 0.3 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.5 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.8 GO:0031045 dense core granule(GO:0031045)
0.0 0.9 GO:0097228 sperm principal piece(GO:0097228)
0.0 1.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 2.6 GO:0005871 kinesin complex(GO:0005871)
0.0 1.1 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.4 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 2.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.2 GO:0097546 ciliary base(GO:0097546)
0.0 1.1 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.1 GO:0070820 tertiary granule(GO:0070820)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 1.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.5 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 1.0 GO:0031985 Golgi cisterna(GO:0031985)
0.0 2.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.7 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.7 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 1.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.0 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.6 GO:0002102 podosome(GO:0002102)
0.0 1.1 GO:0072686 mitotic spindle(GO:0072686)
0.0 1.0 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.6 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.1 GO:0043203 axon hillock(GO:0043203)
0.0 1.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.7 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.7 GO:0001650 fibrillar center(GO:0001650)
0.0 0.8 GO:0030864 cortical actin cytoskeleton(GO:0030864)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0004096 catalase activity(GO:0004096)
0.3 1.2 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.3 1.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.3 1.6 GO:0033691 sialic acid binding(GO:0033691)
0.3 1.1 GO:0050347 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.2 2.0 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.2 1.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 1.4 GO:0051185 coenzyme transporter activity(GO:0051185)
0.2 1.0 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2 1.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 0.9 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 0.5 GO:0003692 left-handed Z-DNA binding(GO:0003692)
0.1 0.9 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.5 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.1 0.6 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.1 0.3 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.1 1.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.7 GO:0001515 opioid peptide activity(GO:0001515)
0.1 1.4 GO:0045499 chemorepellent activity(GO:0045499)
0.1 1.0 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.6 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.1 1.7 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 1.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 2.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.7 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 1.9 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 1.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 1.5 GO:0042056 chemoattractant activity(GO:0042056)
0.1 0.9 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.7 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 2.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.7 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.4 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.3 GO:0016453 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.1 1.0 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 0.5 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1 0.5 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.0 1.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.2 GO:0097643 amylin receptor activity(GO:0097643)
0.0 0.5 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) sulfate transmembrane transporter activity(GO:0015116) oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.1 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0 0.4 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.2 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.5 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.7 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 2.6 GO:0003777 microtubule motor activity(GO:0003777)
0.0 1.0 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 1.0 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.3 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 1.3 GO:0030507 spectrin binding(GO:0030507)
0.0 0.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 1.1 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.1 GO:2001069 glycogen binding(GO:2001069)
0.0 0.3 GO:0043495 protein anchor(GO:0043495)
0.0 1.1 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.3 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.2 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.1 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.3 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.1 1.8 ST_GA12_PATHWAY G alpha 12 Pathway
0.0 1.6 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.0 1.7 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.0 0.9 ST_INTEGRIN_SIGNALING_PATHWAY Integrin Signaling Pathway
0.0 1.1 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.7 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.4 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.4 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 3.5 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 0.6 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.6 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 0.3 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.4 PID_TCR_PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.1 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.0 0.4 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.1 1.7 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 1.6 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 3.0 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.7 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.1 1.0 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.1 1.9 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.9 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.2 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.4 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.0 1.4 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.2 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.0 1.0 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.7 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.2 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.2 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.4 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.4 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.3 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 1.2 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.0 0.3 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.7 REACTOME_REGULATORY_RNA_PATHWAYS Genes involved in Regulatory RNA pathways
0.0 1.8 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.6 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.5 REACTOME_REGULATION_OF_INSULIN_SECRETION Genes involved in Regulation of Insulin Secretion
0.0 1.1 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.4 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.8 REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.5 REACTOME_PLC_BETA_MEDIATED_EVENTS Genes involved in PLC beta mediated events
0.0 0.5 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.3 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.1 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.1 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.3 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor