Motif ID: Mbd2

Z-value: 1.039


Transcription factors associated with Mbd2:

Gene SymbolEntrez IDGene Name
Mbd2 ENSMUSG00000024513.10 Mbd2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mbd2mm10_v2_chr18_+_70568189_705683980.029.0e-01Click!


Activity profile for motif Mbd2.

activity profile for motif Mbd2


Sorted Z-values histogram for motif Mbd2

Sorted Z-values for motif Mbd2



Network of associatons between targets according to the STRING database.



First level regulatory network of Mbd2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_108003414 8.410 ENSMUST00000109887.1
ENSMUST00000109891.2
Bcl11b

B cell leukemia/lymphoma 11B

chr5_-_115194283 3.014 ENSMUST00000112113.1
Cabp1
calcium binding protein 1
chr11_-_75796048 2.994 ENSMUST00000021209.7
Doc2b
double C2, beta
chr12_-_108003594 2.982 ENSMUST00000066060.4
Bcl11b
B cell leukemia/lymphoma 11B
chr5_+_30588078 2.889 ENSMUST00000066295.2
Kcnk3
potassium channel, subfamily K, member 3
chr4_-_120747248 2.698 ENSMUST00000030376.7
Kcnq4
potassium voltage-gated channel, subfamily Q, member 4
chr7_-_126082406 2.693 ENSMUST00000073935.5
Gsg1l
GSG1-like
chr5_+_37028329 2.553 ENSMUST00000173836.1
Jakmip1
janus kinase and microtubule interacting protein 1
chr5_+_36868467 2.497 ENSMUST00000031003.7
Ppp2r2c
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), gamma isoform
chr6_-_126740151 2.421 ENSMUST00000112242.1
Kcna6
potassium voltage-gated channel, shaker-related, subfamily, member 6
chrX_+_152144240 2.311 ENSMUST00000168786.1
ENSMUST00000112605.1
ENSMUST00000112604.1
Iqsec2


IQ motif and Sec7 domain 2


chr14_-_39472825 2.239 ENSMUST00000168810.2
ENSMUST00000173780.1
ENSMUST00000166968.2
Nrg3


neuregulin 3


chr1_+_75375271 2.207 ENSMUST00000087122.5
Speg
SPEG complex locus
chr2_+_35622160 2.029 ENSMUST00000112992.2
Dab2ip
disabled 2 interacting protein
chr11_+_57645417 2.026 ENSMUST00000066987.7
ENSMUST00000108846.1
Galnt10

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10

chr15_-_28025834 2.018 ENSMUST00000090247.5
Trio
triple functional domain (PTPRF interacting)
chr19_+_56722372 1.978 ENSMUST00000038949.4
Adrb1
adrenergic receptor, beta 1
chr2_+_35622010 1.882 ENSMUST00000091010.5
Dab2ip
disabled 2 interacting protein
chr11_+_7063423 1.863 ENSMUST00000020706.4
Adcy1
adenylate cyclase 1
chr17_-_47924460 1.853 ENSMUST00000113262.1
Foxp4
forkhead box P4
chr12_-_79007276 1.844 ENSMUST00000056660.6
ENSMUST00000174721.1
Tmem229b

transmembrane protein 229B

chr9_-_108190352 1.843 ENSMUST00000035208.7
Bsn
bassoon
chr13_+_110395041 1.837 ENSMUST00000022212.7
Plk2
polo-like kinase 2
chr9_-_51008936 1.814 ENSMUST00000176824.1
ENSMUST00000176663.1
ENSMUST00000041375.10
Sik2


salt inducible kinase 2


chr17_-_47924400 1.778 ENSMUST00000113263.1
ENSMUST00000097311.2
Foxp4

forkhead box P4

chr13_-_52981027 1.765 ENSMUST00000071065.7
Nfil3
nuclear factor, interleukin 3, regulated
chr15_-_73645665 1.657 ENSMUST00000130765.1
Slc45a4
solute carrier family 45, member 4
chr16_+_20517000 1.572 ENSMUST00000171572.1
Dvl3
dishevelled 3, dsh homolog (Drosophila)
chr18_-_43393346 1.542 ENSMUST00000025379.7
Dpysl3
dihydropyrimidinase-like 3
chr16_+_20516962 1.536 ENSMUST00000003318.5
Dvl3
dishevelled 3, dsh homolog (Drosophila)
chr7_+_29303938 1.487 ENSMUST00000108231.1
Dpf1
D4, zinc and double PHD fingers family 1
chr7_-_74554474 1.464 ENSMUST00000134539.1
ENSMUST00000026897.7
ENSMUST00000098371.2
Slco3a1


solute carrier organic anion transporter family, member 3a1


chr4_+_133039482 1.425 ENSMUST00000105914.1
Ahdc1
AT hook, DNA binding motif, containing 1
chr7_+_29303958 1.376 ENSMUST00000049977.6
Dpf1
D4, zinc and double PHD fingers family 1
chr16_-_22163299 1.354 ENSMUST00000100052.4
Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr14_-_55116935 1.343 ENSMUST00000022819.5
Jph4
junctophilin 4
chr11_+_104231573 1.332 ENSMUST00000132977.1
ENSMUST00000132245.1
ENSMUST00000100347.4
Mapt


microtubule-associated protein tau


chr13_+_46418266 1.309 ENSMUST00000037923.3
Rbm24
RNA binding motif protein 24
chr11_+_104231465 1.300 ENSMUST00000145227.1
Mapt
microtubule-associated protein tau
chr15_-_85581809 1.283 ENSMUST00000023015.7
Wnt7b
wingless-related MMTV integration site 7B
chr10_+_13966268 1.242 ENSMUST00000015645.4
Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr2_-_27475600 1.236 ENSMUST00000147736.1
Brd3
bromodomain containing 3
chr14_+_25607797 1.233 ENSMUST00000160229.1
Zmiz1
zinc finger, MIZ-type containing 1
chr14_-_24245913 1.210 ENSMUST00000073687.6
ENSMUST00000090398.4
Dlg5

discs, large homolog 5 (Drosophila)

chr11_+_104231515 1.202 ENSMUST00000106993.3
Mapt
microtubule-associated protein tau
chr4_-_148287927 1.170 ENSMUST00000047720.8
Ptchd2
patched domain containing 2
chr10_-_78352469 1.163 ENSMUST00000138035.1
Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr3_+_95658771 1.152 ENSMUST00000178686.1
Mcl1
myeloid cell leukemia sequence 1
chr9_-_106789130 1.133 ENSMUST00000046502.5
Rad54l2
RAD54 like 2 (S. cerevisiae)
chr2_-_166155624 1.120 ENSMUST00000109249.2
Sulf2
sulfatase 2
chr12_-_99393010 1.091 ENSMUST00000177451.1
Foxn3
forkhead box N3
chr5_-_115272883 1.075 ENSMUST00000040555.8
ENSMUST00000112096.2
ENSMUST00000112097.1
Rnf10


ring finger protein 10


chr5_-_36530610 1.073 ENSMUST00000171385.1
Tbc1d14
TBC1 domain family, member 14
chr2_-_24763047 1.072 ENSMUST00000100348.3
ENSMUST00000041342.5
ENSMUST00000114447.1
ENSMUST00000102939.2
ENSMUST00000070864.7
Cacna1b




calcium channel, voltage-dependent, N type, alpha 1B subunit




chr7_+_67952817 1.067 ENSMUST00000005671.8
Igf1r
insulin-like growth factor I receptor
chr17_+_46161111 1.061 ENSMUST00000166563.1
Gtpbp2
GTP binding protein 2
chr11_-_98018308 1.055 ENSMUST00000107561.2
Cacnb1
calcium channel, voltage-dependent, beta 1 subunit
chr4_+_155734800 1.037 ENSMUST00000147721.1
ENSMUST00000127188.2
Tmem240

transmembrane protein 240

chr2_+_28192971 1.019 ENSMUST00000113920.1
Olfm1
olfactomedin 1
chr18_-_13972617 0.996 ENSMUST00000025288.7
Zfp521
zinc finger protein 521
chr9_+_26733845 0.994 ENSMUST00000115269.2
B3gat1
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chr1_+_74854954 0.987 ENSMUST00000160379.2
Cdk5r2
cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chr14_-_68124836 0.980 ENSMUST00000111089.1
ENSMUST00000022638.5
Nefm

neurofilament, medium polypeptide

chr4_+_106911517 0.979 ENSMUST00000072753.6
ENSMUST00000097934.3
Ssbp3

single-stranded DNA binding protein 3

chr2_-_166155272 0.976 ENSMUST00000088086.3
Sulf2
sulfatase 2
chr9_-_24503127 0.958 ENSMUST00000142064.1
ENSMUST00000170356.1
Dpy19l1

dpy-19-like 1 (C. elegans)

chr7_-_120982260 0.956 ENSMUST00000033169.8
Cdr2
cerebellar degeneration-related 2
chr3_+_98382538 0.942 ENSMUST00000178372.1
Zfp697
zinc finger protein 697
chr19_+_6241668 0.938 ENSMUST00000045351.6
Atg2a
autophagy related 2A
chr11_-_35980473 0.937 ENSMUST00000018993.6
Wwc1
WW, C2 and coiled-coil domain containing 1
chr1_+_191718389 0.927 ENSMUST00000110856.1
ENSMUST00000130876.1
Lpgat1

lysophosphatidylglycerol acyltransferase 1

chr18_-_58209926 0.926 ENSMUST00000025497.6
Fbn2
fibrillin 2
chr2_-_94406647 0.925 ENSMUST00000111237.2
ENSMUST00000094801.4
ENSMUST00000111238.1
Ttc17


tetratricopeptide repeat domain 17


chr11_+_121259983 0.919 ENSMUST00000106113.1
Foxk2
forkhead box K2
chr5_+_146384947 0.913 ENSMUST00000110600.1
ENSMUST00000016143.7
Wasf3

WAS protein family, member 3

chr19_-_47464406 0.910 ENSMUST00000111800.2
ENSMUST00000081619.2
Sh3pxd2a

SH3 and PX domains 2A

chr7_+_99381495 0.895 ENSMUST00000037528.8
Gdpd5
glycerophosphodiester phosphodiesterase domain containing 5
chrX_+_151521146 0.891 ENSMUST00000112670.1
ENSMUST00000046962.4
ENSMUST00000112668.2
ENSMUST00000046950.6
Phf8



PHD finger protein 8



chr1_+_74601441 0.876 ENSMUST00000087183.4
ENSMUST00000148456.1
ENSMUST00000113694.1
Stk36


serine/threonine kinase 36


chrX_+_151047170 0.861 ENSMUST00000026296.7
Fgd1
FYVE, RhoGEF and PH domain containing 1
chr10_+_127380799 0.860 ENSMUST00000111628.2
R3hdm2
R3H domain containing 2
chrX_+_151520655 0.860 ENSMUST00000112666.1
ENSMUST00000168501.1
ENSMUST00000112662.2
Phf8


PHD finger protein 8


chr8_-_84800344 0.858 ENSMUST00000099070.3
Nfix
nuclear factor I/X
chr2_+_28193093 0.857 ENSMUST00000100244.3
Olfm1
olfactomedin 1
chr14_+_20707548 0.842 ENSMUST00000022358.7
Zswim8
zinc finger SWIM-type containing 8
chr3_+_89773562 0.838 ENSMUST00000038356.8
Ube2q1
ubiquitin-conjugating enzyme E2Q (putative) 1
chr3_-_108226598 0.836 ENSMUST00000029486.7
ENSMUST00000156371.1
ENSMUST00000141387.1
Sypl2


synaptophysin-like 2


chr11_-_102447647 0.833 ENSMUST00000049057.4
Fam171a2
family with sequence similarity 171, member A2
chr2_+_30982350 0.827 ENSMUST00000061544.4
ENSMUST00000138161.1
ENSMUST00000142232.1
Usp20


ubiquitin specific peptidase 20


chr6_-_120493807 0.814 ENSMUST00000178687.1
Cecr6
cat eye syndrome chromosome region, candidate 6
chr19_-_5688908 0.813 ENSMUST00000113615.2
Pcnxl3
pecanex-like 3 (Drosophila)
chr2_+_32395896 0.804 ENSMUST00000028162.3
Ptges2
prostaglandin E synthase 2
chr9_+_108692116 0.799 ENSMUST00000035220.6
Prkar2a
protein kinase, cAMP dependent regulatory, type II alpha
chr10_-_78352212 0.799 ENSMUST00000146899.1
Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr7_-_47132698 0.795 ENSMUST00000033142.5
Ptpn5
protein tyrosine phosphatase, non-receptor type 5
chr11_-_94474088 0.786 ENSMUST00000107786.1
ENSMUST00000107791.1
ENSMUST00000103166.2
ENSMUST00000107792.1
ENSMUST00000100561.3
ENSMUST00000107793.1
ENSMUST00000107788.1
ENSMUST00000107790.1
ENSMUST00000107789.1
ENSMUST00000107785.1
ENSMUST00000021234.8
Cacna1g










calcium channel, voltage-dependent, T type, alpha 1G subunit










chr11_-_102296618 0.785 ENSMUST00000107132.2
ENSMUST00000073234.2
Atxn7l3

ataxin 7-like 3

chr4_+_43957678 0.771 ENSMUST00000107855.1
Glipr2
GLI pathogenesis-related 2
chr2_-_152398046 0.760 ENSMUST00000063332.8
ENSMUST00000182625.1
Sox12

SRY-box containing gene 12

chr4_+_43957401 0.754 ENSMUST00000030202.7
Glipr2
GLI pathogenesis-related 2
chr1_+_74601548 0.748 ENSMUST00000087186.4
Stk36
serine/threonine kinase 36
chr11_+_78115565 0.744 ENSMUST00000155571.1
Fam222b
family with sequence similarity 222, member B
chr15_-_98871175 0.742 ENSMUST00000178486.2
ENSMUST00000023741.9
Kmt2d

lysine (K)-specific methyltransferase 2D

chr15_+_87625214 0.737 ENSMUST00000068088.6
Fam19a5
family with sequence similarity 19, member A5
chr10_-_18023229 0.735 ENSMUST00000020002.7
Abracl
ABRA C-terminal like
chr5_+_123394782 0.734 ENSMUST00000111596.1
ENSMUST00000068237.5
Mlxip

MLX interacting protein

chr17_+_65782573 0.726 ENSMUST00000161324.1
ENSMUST00000161127.1
Ppp4r1

protein phosphatase 4, regulatory subunit 1

chr16_+_20517076 0.725 ENSMUST00000171774.1
Dvl3
dishevelled 3, dsh homolog (Drosophila)
chr3_+_98382438 0.724 ENSMUST00000056096.8
Zfp697
zinc finger protein 697
chr10_-_118868903 0.724 ENSMUST00000004281.8
Dyrk2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr5_-_122988533 0.722 ENSMUST00000086200.4
ENSMUST00000156474.1
Kdm2b

lysine (K)-specific demethylase 2B

chr15_-_99457712 0.722 ENSMUST00000161948.1
Nckap5l
NCK-associated protein 5-like
chr6_-_124756478 0.714 ENSMUST00000088357.5
Atn1
atrophin 1
chr9_-_44320229 0.709 ENSMUST00000065080.8
C2cd2l
C2 calcium-dependent domain containing 2-like
chr9_-_97018823 0.705 ENSMUST00000055433.4
Spsb4
splA/ryanodine receptor domain and SOCS box containing 4
chr12_-_27342696 0.704 ENSMUST00000079063.5
Sox11
SRY-box containing gene 11
chr8_+_27085520 0.694 ENSMUST00000178514.1
ENSMUST00000033876.7
Gpr124

G protein-coupled receptor 124

chr19_+_10041548 0.689 ENSMUST00000115995.2
Fads3
fatty acid desaturase 3
chr2_+_157914618 0.689 ENSMUST00000109523.1
Vstm2l
V-set and transmembrane domain containing 2-like
chr17_-_45549655 0.684 ENSMUST00000180252.1
Tmem151b
transmembrane protein 151B
chr16_-_18629864 0.683 ENSMUST00000096987.5
Sept5
septin 5
chr7_+_27258725 0.683 ENSMUST00000079258.6
Numbl
numb-like
chr7_-_66689474 0.679 ENSMUST00000068980.3
Asb7
ankyrin repeat and SOCS box-containing 7
chr11_+_104231390 0.673 ENSMUST00000106992.3
Mapt
microtubule-associated protein tau
chr7_+_126272589 0.661 ENSMUST00000056028.9
Sbk1
SH3-binding kinase 1
chr17_+_34031787 0.653 ENSMUST00000044858.8
Rxrb
retinoid X receptor beta
chr6_-_149101506 0.652 ENSMUST00000127727.1
Dennd5b
DENN/MADD domain containing 5B
chr13_+_54949388 0.649 ENSMUST00000026994.7
ENSMUST00000109994.2
Unc5a

unc-5 homolog A (C. elegans)

chr5_-_74068361 0.648 ENSMUST00000119154.1
ENSMUST00000068058.7
Usp46

ubiquitin specific peptidase 46

chr7_-_74013676 0.647 ENSMUST00000026896.4
St8sia2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr7_-_19665005 0.635 ENSMUST00000055242.9
Clptm1
cleft lip and palate associated transmembrane protein 1
chr17_-_47924635 0.627 ENSMUST00000113265.1
Foxp4
forkhead box P4
chr1_-_36558214 0.627 ENSMUST00000154493.1
Sema4c
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr12_-_102878406 0.626 ENSMUST00000045652.6
Btbd7
BTB (POZ) domain containing 7
chr11_+_69901816 0.622 ENSMUST00000177138.1
ENSMUST00000108617.3
ENSMUST00000177476.1
ENSMUST00000061837.4
Neurl4



neuralized homolog 4 (Drosophila)



chr8_+_116943387 0.618 ENSMUST00000109099.3
Atmin
ATM interactor
chr15_-_75747922 0.618 ENSMUST00000062002.4
Mafa
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian)
chr12_-_72408934 0.613 ENSMUST00000078505.7
Rtn1
reticulon 1
chr4_+_149586555 0.605 ENSMUST00000039144.6
Clstn1
calsyntenin 1
chr11_-_96829959 0.592 ENSMUST00000081775.5
Nfe2l1
nuclear factor, erythroid derived 2,-like 1
chr12_-_102704896 0.592 ENSMUST00000178697.1
ENSMUST00000046518.5
Itpk1

inositol 1,3,4-triphosphate 5/6 kinase

chr7_+_3332918 0.592 ENSMUST00000092891.4
Cacng7
calcium channel, voltage-dependent, gamma subunit 7
chr11_-_96829904 0.589 ENSMUST00000107657.1
Nfe2l1
nuclear factor, erythroid derived 2,-like 1
chr3_-_103791075 0.580 ENSMUST00000106845.2
ENSMUST00000029438.8
ENSMUST00000121324.1
Hipk1


homeodomain interacting protein kinase 1


chr15_+_80234071 0.580 ENSMUST00000023048.4
ENSMUST00000166030.1
Mief1

mitochondrial elongation factor 1

chr7_-_65156416 0.573 ENSMUST00000148459.1
ENSMUST00000119118.1
Fam189a1

family with sequence similarity 189, member A1

chr1_+_89454769 0.573 ENSMUST00000027521.8
ENSMUST00000074945.5
Agap1

ArfGAP with GTPase domain, ankyrin repeat and PH domain 1

chr1_-_177258182 0.573 ENSMUST00000111159.1
Akt3
thymoma viral proto-oncogene 3
chr2_+_28205648 0.567 ENSMUST00000102879.3
ENSMUST00000028177.4
Olfm1

olfactomedin 1

chr7_-_27674516 0.563 ENSMUST00000036453.7
ENSMUST00000108341.1
Map3k10

mitogen-activated protein kinase kinase kinase 10

chr5_-_136244865 0.562 ENSMUST00000005188.9
Sh2b2
SH2B adaptor protein 2
chr9_+_26733728 0.560 ENSMUST00000160899.1
ENSMUST00000161431.1
ENSMUST00000159799.1
B3gat1


beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)


chr1_+_91298354 0.560 ENSMUST00000142488.1
ENSMUST00000124832.1
ENSMUST00000147523.1
Scly


selenocysteine lyase


chr10_+_18055711 0.551 ENSMUST00000154718.1
ENSMUST00000126390.1
ENSMUST00000164556.1
ENSMUST00000150029.1
Reps1



RalBP1 associated Eps domain containing protein



chr12_+_81859964 0.551 ENSMUST00000021567.5
Pcnx
pecanex homolog (Drosophila)
chr9_+_95559817 0.546 ENSMUST00000079597.5
Paqr9
progestin and adipoQ receptor family member IX
chr17_+_34032071 0.545 ENSMUST00000174299.1
ENSMUST00000173554.1
Rxrb

retinoid X receptor beta

chr2_+_152293828 0.544 ENSMUST00000028963.7
ENSMUST00000144252.1
Tbc1d20

TBC1 domain family, member 20

chr4_-_155345696 0.544 ENSMUST00000103178.4
Prkcz
protein kinase C, zeta
chr12_+_3806513 0.535 ENSMUST00000172719.1
Dnmt3a
DNA methyltransferase 3A
chr2_+_156613664 0.530 ENSMUST00000169464.2
ENSMUST00000109567.3
Dlgap4

discs, large homolog-associated protein 4 (Drosophila)

chr4_+_43669266 0.530 ENSMUST00000107864.1
Tmem8b
transmembrane protein 8B
chr7_+_19176416 0.529 ENSMUST00000117338.1
Eml2
echinoderm microtubule associated protein like 2
chr15_+_78913916 0.525 ENSMUST00000089378.4
Pdxp
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr11_-_87086752 0.520 ENSMUST00000020801.7
Smg8
smg-8 homolog, nonsense mediated mRNA decay factor (C. elegans)
chr4_+_42950369 0.510 ENSMUST00000084662.5
Dnajb5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr3_-_90509450 0.507 ENSMUST00000107343.1
ENSMUST00000001043.7
ENSMUST00000107344.1
ENSMUST00000076639.4
ENSMUST00000107346.1
ENSMUST00000146740.1
ENSMUST00000107342.1
ENSMUST00000049937.6
Chtop







chromatin target of PRMT1







chr15_-_75566811 0.506 ENSMUST00000065417.8
Ly6h
lymphocyte antigen 6 complex, locus H
chr5_-_66618752 0.506 ENSMUST00000162366.1
Apbb2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr19_-_6118491 0.504 ENSMUST00000113533.1
Sac3d1
SAC3 domain containing 1
chr1_+_75479529 0.499 ENSMUST00000113575.2
ENSMUST00000148980.1
ENSMUST00000050899.6
Tmem198


transmembrane protein 198


chr9_-_20976762 0.498 ENSMUST00000054197.5
S1pr2
sphingosine-1-phosphate receptor 2
chr4_+_43669610 0.497 ENSMUST00000107866.1
Tmem8b
transmembrane protein 8B
chr4_+_42949814 0.493 ENSMUST00000037872.3
ENSMUST00000098112.2
Dnajb5

DnaJ (Hsp40) homolog, subfamily B, member 5

chr2_-_180273488 0.491 ENSMUST00000108891.1
Cables2
CDK5 and Abl enzyme substrate 2
chr10_-_81167896 0.486 ENSMUST00000005064.7
Pias4
protein inhibitor of activated STAT 4
chr9_-_66126559 0.482 ENSMUST00000137542.1
Snx1
sorting nexin 1
chr6_-_124917939 0.481 ENSMUST00000032216.6
Ptms
parathymosin
chr11_-_106920359 0.471 ENSMUST00000167787.1
ENSMUST00000092517.2
Smurf2

SMAD specific E3 ubiquitin protein ligase 2

chr7_+_141949846 0.470 ENSMUST00000172652.1
Brsk2
BR serine/threonine kinase 2
chr14_+_121035538 0.469 ENSMUST00000026635.7
Farp1
FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived)
chr11_-_97574040 0.468 ENSMUST00000107593.1
Srcin1
SRC kinase signaling inhibitor 1
chr6_-_87981482 0.468 ENSMUST00000056403.5
H1fx
H1 histone family, member X
chr7_-_27228605 0.468 ENSMUST00000003850.7
Itpkc
inositol 1,4,5-trisphosphate 3-kinase C
chr1_+_92831614 0.461 ENSMUST00000045970.6
Gpc1
glypican 1
chr11_+_32642706 0.461 ENSMUST00000109366.1
Fbxw11
F-box and WD-40 domain protein 11
chr7_-_105744312 0.461 ENSMUST00000141116.1
Taf10
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr10_+_127380591 0.460 ENSMUST00000166820.1
R3hdm2
R3H domain containing 2
chr11_+_94990996 0.458 ENSMUST00000038696.5
Ppp1r9b
protein phosphatase 1, regulatory subunit 9B
chr8_+_111537000 0.457 ENSMUST00000173506.1
Znrf1
zinc and ring finger 1
chr4_-_130574150 0.455 ENSMUST00000105993.3
Nkain1
Na+/K+ transporting ATPase interacting 1
chr4_-_126753372 0.450 ENSMUST00000030637.7
ENSMUST00000106116.1
Ncdn

neurochondrin

chr11_-_97573929 0.449 ENSMUST00000126287.1
ENSMUST00000107590.1
Srcin1

SRC kinase signaling inhibitor 1

chr11_+_32642826 0.444 ENSMUST00000093205.6
ENSMUST00000076383.7
Fbxw11

F-box and WD-40 domain protein 11

chr7_-_37770757 0.443 ENSMUST00000176680.1
Zfp536
zinc finger protein 536
chr15_-_75566608 0.437 ENSMUST00000163116.1
ENSMUST00000023241.5
Ly6h

lymphocyte antigen 6 complex, locus H

chr1_+_74506044 0.435 ENSMUST00000087215.5
Rqcd1
rcd1 (required for cell differentiation) homolog 1 (S. pombe)
chr8_+_85036906 0.432 ENSMUST00000093360.4
Tnpo2
transportin 2 (importin 3, karyopherin beta 2b)
chr2_-_152831665 0.431 ENSMUST00000156688.1
ENSMUST00000007803.5
Bcl2l1

BCL2-like 1

chr4_-_133339238 0.424 ENSMUST00000105906.1
Wdtc1
WD and tetratricopeptide repeats 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 11.4 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.8 3.9 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.7 2.7 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.7 2.0 GO:1900133 renin secretion into blood stream(GO:0002001) regulation of renin secretion into blood stream(GO:1900133)
0.6 3.8 GO:1904953 Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904953)
0.6 1.8 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.6 1.8 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.6 1.7 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.5 2.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.5 4.5 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.4 1.3 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332) chemoattraction of axon(GO:0061642)
0.4 1.6 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.4 4.3 GO:1901250 regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250)
0.3 2.0 GO:0016266 O-glycan processing(GO:0016266)
0.3 4.7 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.3 1.0 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.3 1.0 GO:2000744 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.3 1.0 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.3 2.9 GO:0030322 stabilization of membrane potential(GO:0030322)
0.3 1.9 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.3 1.1 GO:0044849 estrous cycle(GO:0044849) cholangiocyte apoptotic process(GO:1902488) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.2 1.0 GO:0021586 pons maturation(GO:0021586)
0.2 0.7 GO:0060023 soft palate development(GO:0060023)
0.2 1.2 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.2 0.7 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.2 0.9 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.2 0.9 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.2 0.9 GO:0001887 selenium compound metabolic process(GO:0001887) selenocysteine metabolic process(GO:0016259)
0.2 0.7 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.2 1.1 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.2 0.9 GO:0071692 protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
0.2 0.9 GO:0072675 osteoclast fusion(GO:0072675)
0.2 1.1 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.2 0.7 GO:0009405 pathogenesis(GO:0009405)
0.2 0.9 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.2 1.2 GO:0007296 vitellogenesis(GO:0007296)
0.2 3.0 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.2 0.8 GO:0070459 prolactin secretion(GO:0070459)
0.2 2.3 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.2 0.5 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.2 0.8 GO:2001025 positive regulation of response to drug(GO:2001025)
0.2 1.9 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.2 0.5 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.2 0.5 GO:0038003 opioid receptor signaling pathway(GO:0038003) cellular response to isoquinoline alkaloid(GO:0071317) regulation of opioid receptor signaling pathway(GO:2000474)
0.1 0.6 GO:0046898 response to cycloheximide(GO:0046898)
0.1 0.7 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 0.3 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.1 0.4 GO:0019401 alditol biosynthetic process(GO:0019401)
0.1 2.5 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 0.5 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822)
0.1 1.8 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 0.4 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.1 0.1 GO:0045896 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.1 0.7 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.1 0.4 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.1 3.3 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 0.2 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 1.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 0.5 GO:2000551 regulation of T-helper 2 cell cytokine production(GO:2000551) positive regulation of T-helper 2 cell cytokine production(GO:2000553)
0.1 0.4 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 0.5 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.1 0.5 GO:0070535 histone H2A K63-linked ubiquitination(GO:0070535)
0.1 0.5 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.1 1.7 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.1 1.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.4 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.1 0.4 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 1.1 GO:0033574 response to testosterone(GO:0033574)
0.1 0.6 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 0.6 GO:0050862 adult feeding behavior(GO:0008343) positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 0.3 GO:0060709 glycogen cell differentiation involved in embryonic placenta development(GO:0060709)
0.1 0.5 GO:0051013 microtubule severing(GO:0051013)
0.1 0.9 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.4 GO:0035087 siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.1 0.8 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.8 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 0.6 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.5 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.1 0.6 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.1 0.3 GO:0050812 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.1 0.3 GO:0045358 negative regulation of interferon-beta biosynthetic process(GO:0045358)
0.1 0.7 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.1 0.9 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.1 0.2 GO:0036509 trimming of terminal mannose on B branch(GO:0036509)
0.1 0.3 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 1.5 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.2 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.1 0.4 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.3 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.1 1.5 GO:0055012 ventricular cardiac muscle cell differentiation(GO:0055012)
0.1 1.3 GO:0044804 nucleophagy(GO:0044804)
0.1 1.8 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.1 0.3 GO:0060178 regulation of exocyst localization(GO:0060178)
0.1 0.9 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.1 0.8 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.1 0.8 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.2 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 1.0 GO:0031643 positive regulation of myelination(GO:0031643)
0.0 1.2 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.3 GO:0061072 iris morphogenesis(GO:0061072)
0.0 0.5 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.6 GO:0060693 regulation of branching involved in salivary gland morphogenesis(GO:0060693)
0.0 0.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.2 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.9 GO:0048505 regulation of timing of cell differentiation(GO:0048505)
0.0 0.6 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.3 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.0 0.2 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.0 0.6 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.6 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.8 GO:0043496 regulation of protein homodimerization activity(GO:0043496)
0.0 0.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.2 GO:2001184 regulation of interleukin-12 secretion(GO:2001182) positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.6 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.6 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.0 0.2 GO:0051014 actin filament severing(GO:0051014)
0.0 0.7 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.0 0.4 GO:0006898 receptor-mediated endocytosis(GO:0006898)
0.0 1.7 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626)
0.0 1.1 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.2 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.0 0.3 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 1.3 GO:0055013 cardiac muscle cell development(GO:0055013)
0.0 0.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.6 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.5 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.4 GO:0045453 bone resorption(GO:0045453)
0.0 0.2 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.0 0.8 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 0.3 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.3 GO:0097286 iron ion import(GO:0097286)
0.0 1.0 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.9 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.0 0.5 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 2.7 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.7 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.2 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.1 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.0 0.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.2 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.6 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.9 GO:0051298 centrosome duplication(GO:0051298)
0.0 0.2 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.4 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.5 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.1 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.2 GO:0060135 maternal process involved in female pregnancy(GO:0060135)
0.0 1.7 GO:0008654 phospholipid biosynthetic process(GO:0008654)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.9 GO:1990032 parallel fiber(GO:1990032)
0.6 1.8 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
0.5 4.5 GO:0045298 tubulin complex(GO:0045298)
0.3 3.7 GO:1990909 Wnt signalosome(GO:1990909)
0.3 1.0 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.3 1.3 GO:0030314 junctional membrane complex(GO:0030314)
0.2 0.7 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.2 1.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.2 0.7 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.2 0.5 GO:0030905 retromer, tubulation complex(GO:0030905)
0.2 1.7 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 2.7 GO:0032279 asymmetric synapse(GO:0032279)
0.1 0.4 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1 2.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 2.8 GO:0071565 nBAF complex(GO:0071565)
0.1 1.0 GO:0005883 neurofilament(GO:0005883)
0.1 1.9 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.3 GO:0098830 presynaptic endosome(GO:0098830)
0.1 0.3 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 0.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.5 GO:0045179 apical cortex(GO:0045179)
0.1 3.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.5 GO:0000125 PCAF complex(GO:0000125)
0.1 2.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 0.9 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.7 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 0.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.8 GO:0000124 SAGA complex(GO:0000124)
0.1 5.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 0.4 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 3.0 GO:0031201 SNARE complex(GO:0031201)
0.1 0.8 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.8 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.5 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.3 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.7 GO:0031105 septin complex(GO:0031105)
0.0 0.4 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.2 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.3 GO:0097413 Lewy body(GO:0097413)
0.0 0.5 GO:0070938 contractile ring(GO:0070938)
0.0 1.3 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.9 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.9 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 2.1 GO:0005776 autophagosome(GO:0005776)
0.0 1.4 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.3 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.2 GO:0001740 Barr body(GO:0001740)
0.0 0.6 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 1.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 0.6 GO:0001741 XY body(GO:0001741)
0.0 0.3 GO:0016580 Sin3 complex(GO:0016580)
0.0 1.0 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.9 GO:0002102 podosome(GO:0002102)
0.0 6.0 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.1 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 2.2 GO:0070382 exocytic vesicle(GO:0070382)
0.0 0.6 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.8 GO:0005814 centriole(GO:0005814)
0.0 0.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.1 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.3 GO:0043204 perikaryon(GO:0043204)
0.0 0.4 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.4 GO:0034399 nuclear periphery(GO:0034399)
0.0 0.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.4 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.5 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.9 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.3 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.4 GO:0016592 mediator complex(GO:0016592)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0051379 epinephrine binding(GO:0051379)
0.6 4.5 GO:0099609 microtubule lateral binding(GO:0099609)
0.6 1.8 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.6 3.9 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.6 1.7 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.4 2.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.3 1.3 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.3 1.9 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.3 2.9 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.3 1.6 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.2 0.9 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.2 1.8 GO:0043559 insulin binding(GO:0043559)
0.2 0.9 GO:0070279 vitamin B6 binding(GO:0070279)
0.2 1.5 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.2 0.8 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.2 0.6 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.2 0.8 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.2 1.7 GO:0051434 BH3 domain binding(GO:0051434)
0.2 1.5 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.2 1.5 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 0.9 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.2 0.5 GO:0070052 collagen V binding(GO:0070052)
0.2 2.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.2 0.9 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.6 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.4 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 2.2 GO:0045499 chemorepellent activity(GO:0045499)
0.1 2.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 2.3 GO:0050811 GABA receptor binding(GO:0050811)
0.1 2.6 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 0.5 GO:1990460 leptin receptor binding(GO:1990460)
0.1 0.4 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1 2.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.6 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 0.6 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.6 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.9 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 1.8 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.1 0.4 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 0.5 GO:0051766 inositol trisphosphate kinase activity(GO:0051766)
0.1 1.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 2.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 1.9 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 1.0 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.8 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 0.3 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1 0.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.5 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 3.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 0.3 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.1 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.1 0.4 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 4.6 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 3.7 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.5 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.5 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 0.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 0.2 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.8 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 1.4 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.3 GO:0043426 MRF binding(GO:0043426)
0.0 0.5 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.3 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.2 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.0 0.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.8 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 2.5 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.4 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.2 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 3.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 2.5 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.1 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.8 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 12.3 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.6 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.5 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 1.2 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 1.4 GO:0019003 GDP binding(GO:0019003)
0.0 0.6 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.3 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.2 GO:0048156 tau protein binding(GO:0048156)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.2 GO:0005123 death receptor binding(GO:0005123)
0.0 0.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 1.2 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 1.1 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.7 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.2 GO:0005521 lamin binding(GO:0005521)
0.0 0.6 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.2 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.5 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 4.8 GO:0004674 protein serine/threonine kinase activity(GO:0004674)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.0 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 2.2 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.1 3.9 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.1 1.9 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.1 4.5 PID_RAS_PATHWAY Regulation of Ras family activation
0.1 0.6 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.1 0.5 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.1 1.6 PID_IFNG_PATHWAY IFN-gamma pathway
0.0 0.6 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 1.3 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 1.8 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 3.1 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.6 SIG_IL4RECEPTOR_IN_B_LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 1.1 PID_IGF1_PATHWAY IGF1 pathway
0.0 1.5 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.9 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 0.9 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.0 2.3 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.9 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 1.0 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.5 PID_MYC_PATHWAY C-MYC pathway
0.0 0.4 ST_GAQ_PATHWAY G alpha q Pathway
0.0 1.0 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.7 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 0.8 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.6 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID_TCPTP_PATHWAY Signaling events mediated by TCPTP
0.0 0.5 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.9 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 4.5 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 1.5 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.2 1.9 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.2 2.0 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 5.1 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 0.9 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.1 2.6 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.1 1.6 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 0.9 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 0.8 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 2.0 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 2.3 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.1 0.6 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.1 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.6 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.6 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.6 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.4 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.9 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.4 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.0 0.6 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.4 REACTOME_CA_DEPENDENT_EVENTS Genes involved in Ca-dependent events
0.0 1.5 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 2.1 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.6 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.2 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.0 0.2 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.1 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.3 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.3 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.6 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.6 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.9 REACTOME_ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.7 REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation