Motif ID: Hlf

Z-value: 0.712


Transcription factors associated with Hlf:

Gene SymbolEntrez IDGene Name
Hlf ENSMUSG00000003949.10 Hlf

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hlfmm10_v2_chr11_-_90390895_90390926-0.462.2e-03Click!


Activity profile for motif Hlf.

activity profile for motif Hlf


Sorted Z-values histogram for motif Hlf

Sorted Z-values for motif Hlf



Network of associatons between targets according to the STRING database.



First level regulatory network of Hlf

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_88978958 5.820 ENSMUST00000042594.6
ENSMUST00000109368.1
Mlc1

megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human)

chr2_+_25180737 2.975 ENSMUST00000104999.2
Nrarp
Notch-regulated ankyrin repeat protein
chr4_-_151044564 2.260 ENSMUST00000103204.4
Per3
period circadian clock 3
chr12_+_117843489 2.257 ENSMUST00000021592.9
Cdca7l
cell division cycle associated 7 like
chr11_-_77894096 2.207 ENSMUST00000017597.4
Pipox
pipecolic acid oxidase
chr13_+_23531044 2.170 ENSMUST00000102972.3
Hist1h4h
histone cluster 1, H4h
chr19_+_60144682 2.075 ENSMUST00000065383.4
E330013P04Rik
RIKEN cDNA E330013P04 gene
chr14_+_50955992 1.928 ENSMUST00000095925.4
Pnp2
purine-nucleoside phosphorylase 2
chr9_-_107668967 1.812 ENSMUST00000177567.1
Slc38a3
solute carrier family 38, member 3
chr3_+_127553462 1.764 ENSMUST00000043108.4
4930422G04Rik
RIKEN cDNA 4930422G04 gene
chr14_+_65971049 1.748 ENSMUST00000128539.1
Clu
clusterin
chr3_+_66219909 1.702 ENSMUST00000029421.5
Ptx3
pentraxin related gene
chr4_+_42735545 1.557 ENSMUST00000068158.3
4930578G10Rik
RIKEN cDNA 4930578G10 gene
chr14_+_65971164 1.526 ENSMUST00000144619.1
Clu
clusterin
chr7_+_67647405 1.507 ENSMUST00000032774.8
ENSMUST00000107471.1
Ttc23

tetratricopeptide repeat domain 23

chr1_+_156838915 1.490 ENSMUST00000111720.1
Angptl1
angiopoietin-like 1
chr15_-_50889691 1.486 ENSMUST00000165201.2
ENSMUST00000184458.1
Trps1

trichorhinophalangeal syndrome I (human)

chr14_+_50944499 1.480 ENSMUST00000178092.1
Pnp
purine-nucleoside phosphorylase
chr15_-_98728120 1.462 ENSMUST00000003445.6
Fkbp11
FK506 binding protein 11
chr17_-_31637135 1.449 ENSMUST00000118504.1
ENSMUST00000078509.5
ENSMUST00000067801.6
Cbs


cystathionine beta-synthase


chr2_+_30834972 1.412 ENSMUST00000113592.2
Prrx2
paired related homeobox 2
chr5_+_3343893 1.409 ENSMUST00000165117.1
Cdk6
cyclin-dependent kinase 6
chr7_-_114636299 1.373 ENSMUST00000032906.4
ENSMUST00000032907.7
Calca

calcitonin/calcitonin-related polypeptide, alpha

chr3_+_40800054 1.328 ENSMUST00000168287.1
Plk4
polo-like kinase 4
chr14_+_65970804 1.274 ENSMUST00000138191.1
Clu
clusterin
chr7_+_27447978 1.254 ENSMUST00000037399.9
ENSMUST00000108358.1
Blvrb

biliverdin reductase B (flavin reductase (NADPH))

chr19_-_50678642 1.249 ENSMUST00000072685.6
ENSMUST00000164039.2
Sorcs1

VPS10 domain receptor protein SORCS 1

chr3_+_51559973 1.235 ENSMUST00000180404.1
5031434O11Rik
RIKEN cDNA 5031434O11 gene
chr12_-_110978981 1.208 ENSMUST00000135131.1
ENSMUST00000043459.6
ENSMUST00000128353.1
Ankrd9


ankyrin repeat domain 9


chr18_-_35498856 1.208 ENSMUST00000025215.8
Sil1
endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae)
chr6_+_83034173 1.160 ENSMUST00000000707.2
ENSMUST00000101257.3
Loxl3

lysyl oxidase-like 3

chr11_-_101785252 1.149 ENSMUST00000164750.1
ENSMUST00000107176.1
ENSMUST00000017868.6
Etv4


ets variant gene 4 (E1A enhancer binding protein, E1AF)


chr3_+_84952146 1.111 ENSMUST00000029727.7
Fbxw7
F-box and WD-40 domain protein 7
chr10_+_20347788 1.070 ENSMUST00000169712.1
Mtfr2
mitochondrial fission regulator 2
chr5_-_124032214 1.063 ENSMUST00000040967.7
Vps37b
vacuolar protein sorting 37B (yeast)
chr18_+_50030977 1.041 ENSMUST00000145726.1
ENSMUST00000128377.1
Tnfaip8

tumor necrosis factor, alpha-induced protein 8

chr6_+_90465287 1.027 ENSMUST00000113530.1
Klf15
Kruppel-like factor 15
chr1_+_10993452 1.004 ENSMUST00000027056.5
Prex2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr19_-_28963863 0.991 ENSMUST00000161813.1
4430402I18Rik
RIKEN cDNA 4430402I18 gene
chr17_+_47737030 0.985 ENSMUST00000086932.3
Tfeb
transcription factor EB
chr3_-_127553233 0.943 ENSMUST00000029588.5
Larp7
La ribonucleoprotein domain family, member 7
chr9_-_100506844 0.941 ENSMUST00000112874.3
Nck1
non-catalytic region of tyrosine kinase adaptor protein 1
chr13_-_106847267 0.940 ENSMUST00000057427.4
Lrrc70
leucine rich repeat containing 70
chr14_+_26122609 0.902 ENSMUST00000100810.6
Duxbl2
doubl homeobox B-like 2
chr17_+_32284772 0.870 ENSMUST00000181112.1
Gm26549
predicted gene, 26549
chr3_+_51559757 0.865 ENSMUST00000180616.1
5031434O11Rik
RIKEN cDNA 5031434O11 gene
chr3_+_87906321 0.861 ENSMUST00000005017.8
Hdgf
hepatoma-derived growth factor
chr4_+_111720187 0.856 ENSMUST00000084354.3
Spata6
spermatogenesis associated 6
chr15_+_44619551 0.856 ENSMUST00000022964.7
Ebag9
estrogen receptor-binding fragment-associated gene 9
chr6_+_17463749 0.836 ENSMUST00000115443.1
Met
met proto-oncogene
chr2_+_120609383 0.835 ENSMUST00000124187.1
Haus2
HAUS augmin-like complex, subunit 2
chr11_+_69045640 0.835 ENSMUST00000108666.1
ENSMUST00000021277.5
Aurkb

aurora kinase B

chr6_+_124808885 0.816 ENSMUST00000143040.1
ENSMUST00000052727.4
ENSMUST00000130160.1
Spsb2


splA/ryanodine receptor domain and SOCS box containing 2


chr16_+_92292380 0.815 ENSMUST00000047383.3
Kcne2
potassium voltage-gated channel, Isk-related subfamily, gene 2
chr8_-_92355764 0.811 ENSMUST00000180102.1
ENSMUST00000179421.1
ENSMUST00000179222.1
ENSMUST00000179029.1
4933436C20Rik



RIKEN cDNA 4933436C20 gene



chr12_-_69159109 0.801 ENSMUST00000037023.8
Rps29
ribosomal protein S29
chr7_+_18884679 0.798 ENSMUST00000032573.6
Pglyrp1
peptidoglycan recognition protein 1
chr7_+_90442729 0.781 ENSMUST00000061767.4
ENSMUST00000107206.1
Crebzf

CREB/ATF bZIP transcription factor

chr3_+_97158767 0.771 ENSMUST00000090759.4
Acp6
acid phosphatase 6, lysophosphatidic
chr15_+_34238026 0.749 ENSMUST00000022867.3
Laptm4b
lysosomal-associated protein transmembrane 4B
chr6_-_83033422 0.732 ENSMUST00000089651.5
Dok1
docking protein 1
chrX_+_75095854 0.725 ENSMUST00000033776.8
Dkc1
dyskeratosis congenita 1, dyskerin
chr9_+_115909455 0.722 ENSMUST00000119291.1
ENSMUST00000069651.6
Gadl1

glutamate decarboxylase-like 1

chr5_-_5514730 0.718 ENSMUST00000115445.1
ENSMUST00000179804.1
ENSMUST00000125110.1
ENSMUST00000115446.1
Cldn12



claudin 12



chr9_+_38719024 0.700 ENSMUST00000129598.1
Vwa5a
von Willebrand factor A domain containing 5A
chr3_+_40800013 0.700 ENSMUST00000026858.5
ENSMUST00000170825.1
Plk4

polo-like kinase 4

chr8_-_4275886 0.695 ENSMUST00000003029.7
Timm44
translocase of inner mitochondrial membrane 44
chr2_+_109280738 0.688 ENSMUST00000028527.7
Kif18a
kinesin family member 18A
chr15_+_25758755 0.687 ENSMUST00000131834.1
ENSMUST00000124966.1
Myo10

myosin X

chr5_-_5514873 0.683 ENSMUST00000060947.7
Cldn12
claudin 12
chr11_-_88718223 0.683 ENSMUST00000107909.1
Msi2
musashi RNA-binding protein 2
chr10_+_100488289 0.681 ENSMUST00000164751.1
Cep290
centrosomal protein 290
chr3_+_86070915 0.677 ENSMUST00000182666.1
Sh3d19
SH3 domain protein D19
chr8_-_33929798 0.669 ENSMUST00000033995.7
ENSMUST00000033994.8
ENSMUST00000053251.5
Rbpms


RNA binding protein gene with multiple splicing


chr11_-_6444352 0.665 ENSMUST00000093346.5
ENSMUST00000109737.2
H2afv

H2A histone family, member V

chr2_+_132847719 0.658 ENSMUST00000124836.1
ENSMUST00000154160.1
Crls1

cardiolipin synthase 1

chr15_+_99074968 0.653 ENSMUST00000039665.6
Troap
trophinin associated protein
chr2_+_76650264 0.652 ENSMUST00000099986.2
Dfnb59
deafness, autosomal recessive 59 (human)
chr17_+_36958623 0.650 ENSMUST00000173814.1
Znrd1as
Znrd1 antisense
chr11_-_69980468 0.638 ENSMUST00000143175.1
Elp5
elongator acetyltransferase complex subunit 5
chr19_+_43752996 0.634 ENSMUST00000026199.7
ENSMUST00000112047.3
ENSMUST00000153295.1
Cutc


cutC copper transporter homolog (E.coli)


chr17_+_36958571 0.624 ENSMUST00000040177.6
Znrd1as
Znrd1 antisense
chr12_+_110279228 0.614 ENSMUST00000097228.4
Dio3
deiodinase, iodothyronine type III
chr18_-_80713062 0.606 ENSMUST00000170905.1
ENSMUST00000078049.4
Nfatc1

nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1

chr7_-_46667375 0.597 ENSMUST00000107669.2
Tph1
tryptophan hydroxylase 1
chr10_+_96616998 0.589 ENSMUST00000038377.7
Btg1
B cell translocation gene 1, anti-proliferative
chr11_+_119022962 0.585 ENSMUST00000026662.7
Cbx2
chromobox 2
chr16_-_57606816 0.585 ENSMUST00000114371.3
Cmss1
cms small ribosomal subunit 1
chr1_+_92831614 0.567 ENSMUST00000045970.6
Gpc1
glypican 1
chr4_-_97584605 0.565 ENSMUST00000107067.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr7_-_13034722 0.542 ENSMUST00000005711.4
Chmp2a
charged multivesicular body protein 2A
chr4_-_89311021 0.542 ENSMUST00000097981.4
Cdkn2b
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
chr4_-_97584612 0.535 ENSMUST00000107068.2
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr14_+_66784523 0.521 ENSMUST00000071522.2
Gm10032
predicted gene 10032
chr2_-_109280718 0.515 ENSMUST00000147770.1
Mettl15
methyltransferase like 15
chr16_+_78930940 0.514 ENSMUST00000114216.1
ENSMUST00000069148.6
ENSMUST00000023568.7
Chodl


chondrolectin


chr17_+_84511832 0.484 ENSMUST00000047206.5
Plekhh2
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr17_-_45592485 0.482 ENSMUST00000166119.1
Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr10_-_22149270 0.472 ENSMUST00000179054.1
ENSMUST00000069372.6
E030030I06Rik

RIKEN cDNA E030030I06 gene

chr3_+_96104498 0.467 ENSMUST00000132980.1
ENSMUST00000138206.1
ENSMUST00000090785.2
ENSMUST00000035519.5
Otud7b



OTU domain containing 7B



chr7_+_110773658 0.459 ENSMUST00000143786.1
Ampd3
adenosine monophosphate deaminase 3
chr10_-_31445921 0.457 ENSMUST00000000305.5
Tpd52l1
tumor protein D52-like 1
chr17_-_45592569 0.453 ENSMUST00000163492.1
Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr1_+_74791516 0.448 ENSMUST00000006718.8
Wnt10a
wingless related MMTV integration site 10a
chr4_+_150237694 0.445 ENSMUST00000141931.1
Eno1
enolase 1, alpha non-neuron
chr4_+_47208005 0.438 ENSMUST00000082303.6
ENSMUST00000102917.4
Col15a1

collagen, type XV, alpha 1

chr7_-_133782721 0.428 ENSMUST00000063669.1
Dhx32
DEAH (Asp-Glu-Ala-His) box polypeptide 32
chr11_+_80300866 0.427 ENSMUST00000017836.7
Rhbdl3
rhomboid, veinlet-like 3 (Drosophila)
chr5_-_92328068 0.426 ENSMUST00000113093.3
Cxcl9
chemokine (C-X-C motif) ligand 9
chr7_+_44468051 0.422 ENSMUST00000118493.1
Josd2
Josephin domain containing 2
chr12_-_73286698 0.414 ENSMUST00000116420.2
Trmt5
TRM5 tRNA methyltransferase 5
chrX_+_166238901 0.404 ENSMUST00000112235.1
Gpm6b
glycoprotein m6b
chr7_+_44496588 0.403 ENSMUST00000107927.3
Fam71e1
family with sequence similarity 71, member E1
chr10_+_80141457 0.403 ENSMUST00000105367.1
Atp5d
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr4_-_147868631 0.399 ENSMUST00000030886.8
ENSMUST00000172710.1
Miip

migration and invasion inhibitory protein

chr10_-_17947997 0.395 ENSMUST00000037879.6
Heca
headcase homolog (Drosophila)
chr2_+_181497165 0.390 ENSMUST00000149163.1
ENSMUST00000000844.8
ENSMUST00000184849.1
ENSMUST00000108800.1
ENSMUST00000069712.2
Tpd52l2




tumor protein D52-like 2




chr8_-_84840627 0.388 ENSMUST00000003911.6
ENSMUST00000109761.2
ENSMUST00000128035.1
Rad23a


RAD23a homolog (S. cerevisiae)


chr17_-_47691403 0.387 ENSMUST00000113299.1
ENSMUST00000152214.1
Gm21981
Prickle4
predicted gene 21981
prickle homolog 4 (Drosophila)
chr4_-_147868469 0.381 ENSMUST00000119975.2
Miip
migration and invasion inhibitory protein
chr12_+_98771018 0.378 ENSMUST00000021399.7
Zc3h14
zinc finger CCCH type containing 14
chr2_+_155940728 0.372 ENSMUST00000109629.1
Gm15557
predicted gene 15557
chr13_+_49504774 0.370 ENSMUST00000051504.7
Ecm2
extracellular matrix protein 2, female organ and adipocyte specific
chr7_-_42578588 0.370 ENSMUST00000179470.1
Gm21028
predicted gene, 21028
chrX_-_36864238 0.369 ENSMUST00000115249.3
ENSMUST00000115248.3
C330007P06Rik

RIKEN cDNA C330007P06 gene

chr17_-_14694223 0.362 ENSMUST00000170872.1
Thbs2
thrombospondin 2
chr10_+_22645011 0.350 ENSMUST00000042261.4
Slc2a12
solute carrier family 2 (facilitated glucose transporter), member 12
chr12_-_104865076 0.347 ENSMUST00000109937.1
ENSMUST00000109936.1
Clmn

calmin

chr10_-_62507737 0.347 ENSMUST00000020271.6
Srgn
serglycin
chr11_-_101551837 0.345 ENSMUST00000017290.4
Brca1
breast cancer 1
chr7_+_30413744 0.343 ENSMUST00000032800.9
Tyrobp
TYRO protein tyrosine kinase binding protein
chr18_-_36726730 0.339 ENSMUST00000061829.6
Cd14
CD14 antigen
chr4_+_130360132 0.332 ENSMUST00000105994.3
Snrnp40
small nuclear ribonucleoprotein 40 (U5)
chr11_+_69323963 0.330 ENSMUST00000102602.1
Trappc1
trafficking protein particle complex 1
chrX_-_155216444 0.329 ENSMUST00000026318.8
Sat1
spermidine/spermine N1-acetyl transferase 1
chr1_-_38129618 0.327 ENSMUST00000027251.6
Rev1
REV1 homolog (S. cerevisiae)
chr7_+_103550368 0.327 ENSMUST00000106888.1
Olfr613
olfactory receptor 613
chr11_-_69323768 0.318 ENSMUST00000092973.5
Cntrob
centrobin, centrosomal BRCA2 interacting protein
chr8_+_123477859 0.316 ENSMUST00000001520.7
Afg3l1
AFG3(ATPase family gene 3)-like 1 (yeast)
chr7_-_44496406 0.316 ENSMUST00000118515.1
ENSMUST00000138328.1
ENSMUST00000008284.8
ENSMUST00000118808.1
Emc10



ER membrane protein complex subunit 10



chr10_-_128547722 0.315 ENSMUST00000040572.3
Zc3h10
zinc finger CCCH type containing 10
chr1_-_140183404 0.313 ENSMUST00000066859.6
ENSMUST00000111976.2
Cfh

complement component factor h

chr3_+_89459118 0.306 ENSMUST00000029564.5
Pmvk
phosphomevalonate kinase
chr14_+_78849171 0.305 ENSMUST00000040990.5
Vwa8
von Willebrand factor A domain containing 8
chr8_-_122476036 0.300 ENSMUST00000014614.3
Rnf166
ring finger protein 166
chr18_+_82914632 0.297 ENSMUST00000071233.6
Zfp516
zinc finger protein 516
chr10_+_88731056 0.290 ENSMUST00000116234.2
Arl1
ADP-ribosylation factor-like 1
chr11_+_6415443 0.287 ENSMUST00000132846.1
Ppia
peptidylprolyl isomerase A
chr11_+_69324069 0.286 ENSMUST00000060956.6
ENSMUST00000108662.1
Trappc1

trafficking protein particle complex 1

chrX_-_155216338 0.282 ENSMUST00000112551.3
Sat1
spermidine/spermine N1-acetyl transferase 1
chr5_+_115279666 0.282 ENSMUST00000040421.4
Coq5
coenzyme Q5 homolog, methyltransferase (yeast)
chr3_+_90062781 0.275 ENSMUST00000029551.2
1700094D03Rik
RIKEN cDNA 1700094D03 gene
chr11_+_69324055 0.273 ENSMUST00000102601.3
Trappc1
trafficking protein particle complex 1
chr10_+_121739915 0.273 ENSMUST00000065600.7
ENSMUST00000136432.1
BC048403

cDNA sequence BC048403

chr4_-_108833608 0.271 ENSMUST00000102742.4
Btf3l4
basic transcription factor 3-like 4
chr17_+_32036098 0.259 ENSMUST00000081339.6
Rrp1b
ribosomal RNA processing 1 homolog B (S. cerevisiae)
chr2_+_69670100 0.259 ENSMUST00000100050.3
Klhl41
kelch-like 41
chr16_+_91391721 0.258 ENSMUST00000160764.1
Gm21970
predicted gene 21970
chr11_+_110997487 0.255 ENSMUST00000106635.1
Kcnj16
potassium inwardly-rectifying channel, subfamily J, member 16
chr7_+_138846335 0.252 ENSMUST00000041097.6
Ppp2r2d
protein phosphatase 2, regulatory subunit B, delta isoform
chr10_+_128821745 0.248 ENSMUST00000105230.2
Sarnp
SAP domain containing ribonucleoprotein
chr7_+_110774240 0.240 ENSMUST00000147587.1
Ampd3
adenosine monophosphate deaminase 3
chr8_-_92356103 0.238 ENSMUST00000034183.3
4933436C20Rik
RIKEN cDNA 4933436C20 gene
chr10_-_111997204 0.237 ENSMUST00000074805.5
Glipr1
GLI pathogenesis-related 1 (glioma)
chr16_-_4789984 0.236 ENSMUST00000004173.5
Cdip1
cell death inducing Trp53 target 1
chr7_+_132931142 0.232 ENSMUST00000106157.1
Zranb1
zinc finger, RAN-binding domain containing 1
chr7_+_138846579 0.228 ENSMUST00000155672.1
Ppp2r2d
protein phosphatase 2, regulatory subunit B, delta isoform
chr1_-_140183283 0.227 ENSMUST00000111977.1
Cfh
complement component factor h
chr4_-_11981265 0.222 ENSMUST00000098260.2
Gm10604
predicted gene 10604
chr2_+_172472512 0.222 ENSMUST00000029007.2
Fam209
family with sequence similarity 209
chr2_+_181497223 0.221 ENSMUST00000108799.3
Tpd52l2
tumor protein D52-like 2
chr2_+_116900152 0.218 ENSMUST00000126467.1
ENSMUST00000128305.1
ENSMUST00000155323.1
D330050G23Rik


RIKEN cDNA D330050G23 gene


chr9_-_71163224 0.218 ENSMUST00000074465.2
Aqp9
aquaporin 9
chr13_+_93771656 0.217 ENSMUST00000091403.4
Arsb
arylsulfatase B
chr19_-_24961545 0.216 ENSMUST00000025815.8
Cbwd1
COBW domain containing 1
chr2_-_38644087 0.216 ENSMUST00000028083.5
Psmb7
proteasome (prosome, macropain) subunit, beta type 7
chr16_-_94370695 0.215 ENSMUST00000113906.2
Pigp
phosphatidylinositol glycan anchor biosynthesis, class P
chr3_+_142496924 0.211 ENSMUST00000090127.2
Gbp5
guanylate binding protein 5
chr9_+_64179289 0.210 ENSMUST00000034965.6
Snapc5
small nuclear RNA activating complex, polypeptide 5
chr13_-_100650981 0.210 ENSMUST00000022136.6
ENSMUST00000177848.1
Rad17

RAD17 homolog (S. pombe)

chr10_-_128821576 0.209 ENSMUST00000026409.3
Ormdl2
ORM1-like 2 (S. cerevisiae)
chr3_-_88762244 0.206 ENSMUST00000183267.1
Syt11
synaptotagmin XI
chr17_-_43543639 0.203 ENSMUST00000178772.1
Ankrd66
ankyrin repeat domain 66
chr16_-_3907651 0.199 ENSMUST00000177221.1
ENSMUST00000177323.1
1700037C18Rik

RIKEN cDNA 1700037C18 gene

chr15_+_99393610 0.196 ENSMUST00000159531.1
Tmbim6
transmembrane BAX inhibitor motif containing 6
chr13_+_51100810 0.186 ENSMUST00000095797.5
Spin1
spindlin 1
chr7_-_35056467 0.182 ENSMUST00000130491.1
Cebpg
CCAAT/enhancer binding protein (C/EBP), gamma
chr17_-_83514311 0.180 ENSMUST00000167741.1
ENSMUST00000025095.7
Cox7a2l

cytochrome c oxidase subunit VIIa polypeptide 2-like

chr5_-_147894804 0.180 ENSMUST00000118527.1
ENSMUST00000031655.3
ENSMUST00000138244.1
Slc46a3


solute carrier family 46, member 3


chr2_+_164879358 0.179 ENSMUST00000041643.3
Pcif1
PDX1 C-terminal inhibiting factor 1
chr4_-_98817537 0.174 ENSMUST00000102790.3
Kank4
KN motif and ankyrin repeat domains 4
chr3_-_80913528 0.163 ENSMUST00000107743.1
ENSMUST00000029654.8
Glrb

glycine receptor, beta subunit

chr16_-_4790220 0.161 ENSMUST00000118703.1
Cdip1
cell death inducing Trp53 target 1
chr4_-_134245579 0.158 ENSMUST00000030644.7
Zfp593
zinc finger protein 593
chr19_+_34290653 0.154 ENSMUST00000025691.5
ENSMUST00000112472.2
Fas

Fas (TNF receptor superfamily member 6)

chr14_+_70577839 0.154 ENSMUST00000089049.2
Nudt18
nudix (nucleoside diphosphate linked moiety X)-type motif 18
chr2_+_104027721 0.152 ENSMUST00000028603.3
Fbxo3
F-box protein 3
chr13_+_114818232 0.147 ENSMUST00000166104.2
ENSMUST00000166176.2
ENSMUST00000184335.1
ENSMUST00000184245.1
ENSMUST00000015680.4
ENSMUST00000184214.1
ENSMUST00000165022.2
ENSMUST00000164737.1
ENSMUST00000184781.1
ENSMUST00000183407.1
ENSMUST00000184672.1
Mocs2










molybdenum cofactor synthesis 2










chr16_-_4789887 0.140 ENSMUST00000117713.1
Cdip1
cell death inducing Trp53 target 1
chr17_+_28691342 0.132 ENSMUST00000114758.1
ENSMUST00000004990.6
ENSMUST00000062694.8
ENSMUST00000114754.1
Mapk14



mitogen-activated protein kinase 14




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.5 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.7 2.2 GO:0006553 lysine metabolic process(GO:0006553)
0.6 5.9 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.5 0.5 GO:1903722 regulation of centriole elongation(GO:1903722)
0.5 1.5 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.5 1.4 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.5 1.4 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978)
0.4 1.8 GO:0015817 glutamine transport(GO:0006868) histidine transport(GO:0015817) cellular response to potassium ion starvation(GO:0051365)
0.4 1.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.3 1.7 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.3 1.0 GO:0009814 defense response, incompatible interaction(GO:0009814)
0.3 0.9 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.3 1.2 GO:2000319 negative regulation of T-helper 17 type immune response(GO:2000317) regulation of T-helper 17 cell differentiation(GO:2000319) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.3 2.0 GO:0098535 positive regulation of centriole replication(GO:0046601) de novo centriole assembly(GO:0098535)
0.3 2.0 GO:0044838 cell quiescence(GO:0044838)
0.3 0.8 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.3 3.0 GO:0014807 regulation of somitogenesis(GO:0014807)
0.3 0.8 GO:0051715 cytolysis in other organism(GO:0051715)
0.2 1.1 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.2 0.6 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.2 1.1 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600) regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.2 0.6 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.2 2.3 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.2 1.3 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1 0.7 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.1 0.7 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 0.8 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.1 0.9 GO:0015862 uridine transport(GO:0015862)
0.1 0.8 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.1 0.3 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 0.3 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.1 2.2 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.1 0.6 GO:0055070 copper ion homeostasis(GO:0055070)
0.1 0.4 GO:1900864 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.1 0.7 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.1 0.6 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 0.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.6 GO:0046549 phenol-containing compound catabolic process(GO:0019336) retinal cone cell development(GO:0046549)
0.1 0.9 GO:0035562 negative regulation of chromatin binding(GO:0035562) germ cell proliferation(GO:0036093)
0.1 0.3 GO:2000484 response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726) positive regulation of interleukin-8 secretion(GO:2000484)
0.1 0.7 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.1 0.4 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.3 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.6 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.1 0.2 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.1 0.2 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
0.1 0.2 GO:1990927 negative regulation of tumor necrosis factor secretion(GO:1904468) negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927)
0.1 1.0 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1 0.3 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.1 1.5 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.1 0.3 GO:2001204 regulation of osteoclast development(GO:2001204)
0.1 0.3 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 0.5 GO:0070475 rRNA base methylation(GO:0070475)
0.1 0.2 GO:0009182 purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066) GDP metabolic process(GO:0046710) guanosine-containing compound catabolic process(GO:1901069)
0.0 0.4 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 1.4 GO:0042474 middle ear morphogenesis(GO:0042474)
0.0 0.7 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.7 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.7 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.2 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.9 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.3 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.1 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0 0.2 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.0 0.4 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.1 GO:1901079 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738) positive regulation of relaxation of muscle(GO:1901079) regulation of dense core granule biogenesis(GO:2000705)
0.0 0.1 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.1 GO:1905077 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915) negative regulation of interleukin-17 secretion(GO:1905077)
0.0 0.2 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.0 0.3 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.3 GO:0046689 response to mercury ion(GO:0046689)
0.0 0.2 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.2 GO:0045072 regulation of interferon-gamma biosynthetic process(GO:0045072) positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.1 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0 0.5 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 1.3 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 1.0 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 0.1 GO:0055118 negative regulation of cardiac muscle contraction(GO:0055118)
0.0 0.5 GO:0031670 cellular response to nutrient(GO:0031670)
0.0 1.1 GO:0032611 interleukin-1 beta production(GO:0032611)
0.0 0.1 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.0 0.3 GO:0034982 mitochondrial protein processing(GO:0034982)
0.0 0.7 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.3 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.0 1.5 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 1.1 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.6 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.2 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.1 GO:0033210 leptin-mediated signaling pathway(GO:0033210)
0.0 0.1 GO:0010991 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.2 GO:0002082 regulation of oxidative phosphorylation(GO:0002082)
0.0 0.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.4 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0006551 leucine metabolic process(GO:0006551)
0.0 0.2 GO:0007143 female meiotic division(GO:0007143)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.5 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.3 2.0 GO:0098536 deuterosome(GO:0098536)
0.3 1.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.2 0.7 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.2 0.8 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 1.2 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.5 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.1 0.8 GO:0070652 HAUS complex(GO:0070652)
0.1 0.7 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.6 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.3 GO:0005745 m-AAA complex(GO:0005745)
0.1 0.9 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.3 GO:0070531 BRCA1-A complex(GO:0070531)
0.1 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 1.9 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.9 GO:0030008 TRAPP complex(GO:0030008)
0.1 0.5 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.2 GO:0035339 SPOTS complex(GO:0035339)
0.1 0.4 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 5.8 GO:0005901 caveola(GO:0005901)
0.0 0.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.3 GO:0042629 mast cell granule(GO:0042629)
0.0 0.7 GO:0036038 MKS complex(GO:0036038)
0.0 0.2 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.6 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.7 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.4 GO:0031091 platelet alpha granule(GO:0031091)
0.0 0.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.2 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.3 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0031143 pseudopodium(GO:0031143)
0.0 2.6 GO:0043195 terminal bouton(GO:0043195)
0.0 1.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 1.7 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.7 GO:0000786 nucleosome(GO:0000786)
0.0 0.6 GO:0030686 90S preribosome(GO:0030686)
0.0 0.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 2.3 GO:0001650 fibrillar center(GO:0001650)
0.0 0.2 GO:0000346 transcription export complex(GO:0000346)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.7 GO:0016459 myosin complex(GO:0016459)
0.0 1.9 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.6 1.8 GO:0015182 L-asparagine transmembrane transporter activity(GO:0015182)
0.6 2.2 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.5 1.4 GO:0098809 nitrite reductase activity(GO:0098809)
0.5 1.4 GO:0098770 FBXO family protein binding(GO:0098770)
0.3 1.3 GO:0004074 biliverdin reductase activity(GO:0004074)
0.3 0.9 GO:0070052 collagen V binding(GO:0070052)
0.3 1.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.2 1.7 GO:0001849 complement component C1q binding(GO:0001849)
0.2 1.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.2 0.8 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.2 0.6 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.2 0.6 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.2 0.8 GO:0042834 peptidoglycan binding(GO:0042834)
0.2 0.6 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.2 4.5 GO:0051787 misfolded protein binding(GO:0051787)
0.2 0.9 GO:0032027 myosin light chain binding(GO:0032027)
0.2 0.3 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.2 0.8 GO:0035174 histone serine kinase activity(GO:0035174)
0.2 0.8 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.2 0.9 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.5 GO:0001851 complement component C3b binding(GO:0001851)
0.1 0.7 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.7 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.5 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 0.7 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.8 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 0.4 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.4 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 1.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.5 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.2 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.2 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.4 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 0.2 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.1 0.2 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.0 0.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 5.3 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.3 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 1.4 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.5 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.9 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.2 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.5 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.1 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.7 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.7 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.4 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.7 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 1.0 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.2 GO:0050733 RS domain binding(GO:0050733)
0.0 0.4 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.3 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.1 GO:0045340 mercury ion binding(GO:0045340)
0.0 1.4 GO:0005179 hormone activity(GO:0005179)
0.0 0.6 GO:0005507 copper ion binding(GO:0005507)
0.0 0.7 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.7 GO:0051087 chaperone binding(GO:0051087)
0.0 0.2 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.7 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.6 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.7 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.5 GO:0030332 cyclin binding(GO:0030332)
0.0 2.6 GO:0042393 histone binding(GO:0042393)
0.0 1.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.1 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.0 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.0 0.4 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.4 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.1 PID_MYC_PATHWAY C-MYC pathway
0.0 1.8 PID_ARF6_PATHWAY Arf6 signaling events
0.0 1.7 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.2 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 0.7 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.2 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.7 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.0 0.8 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 0.6 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.7 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.5 PID_IL23_PATHWAY IL23-mediated signaling events
0.0 0.7 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.4 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 0.9 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.7 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.3 NABA_PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.1 1.2 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.1 0.5 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.1 1.1 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 1.5 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 0.7 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.1 3.5 REACTOME_AMYLOIDS Genes involved in Amyloids
0.1 0.6 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.1 5.3 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 1.4 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 1.3 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.8 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 3.4 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 2.0 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 1.4 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.3 REACTOME_TRAF6_MEDIATED_INDUCTION_OF_TAK1_COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 0.7 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 0.3 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.2 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.2 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.3 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.3 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.4 REACTOME_SIGNALING_BY_PDGF Genes involved in Signaling by PDGF
0.0 0.7 REACTOME_KINESINS Genes involved in Kinesins
0.0 0.7 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.0 1.0 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.4 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.9 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.5 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.8 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.4 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 1.1 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.8 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.8 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.4 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.1 REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.7 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.4 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.3 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis