Motif ID: Hmx1
Z-value: 0.802

Transcription factors associated with Hmx1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Hmx1 | ENSMUSG00000067438.3 | Hmx1 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.6 | 4.9 | GO:0072382 | minus-end-directed vesicle transport along microtubule(GO:0072382) |
1.4 | 4.2 | GO:0032877 | positive regulation of DNA endoreduplication(GO:0032877) |
1.4 | 5.5 | GO:2000048 | negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048) |
1.3 | 4.0 | GO:0097212 | lysosomal membrane organization(GO:0097212) |
0.9 | 3.5 | GO:1901492 | positive regulation of lymphangiogenesis(GO:1901492) |
0.7 | 2.2 | GO:0060010 | Sertoli cell fate commitment(GO:0060010) |
0.7 | 4.3 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
0.6 | 0.6 | GO:2000040 | regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041) |
0.6 | 3.0 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
0.5 | 1.6 | GO:1905000 | regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000) |
0.5 | 3.4 | GO:0000320 | re-entry into mitotic cell cycle(GO:0000320) |
0.4 | 1.7 | GO:0014722 | regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722) |
0.4 | 1.9 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
0.3 | 1.0 | GO:0036228 | protein targeting to nuclear inner membrane(GO:0036228) |
0.3 | 3.0 | GO:0006104 | succinyl-CoA metabolic process(GO:0006104) |
0.3 | 5.4 | GO:2000353 | positive regulation of endothelial cell apoptotic process(GO:2000353) |
0.3 | 1.4 | GO:1904996 | positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996) |
0.3 | 3.7 | GO:0071481 | cellular response to X-ray(GO:0071481) |
0.3 | 8.2 | GO:0043153 | entrainment of circadian clock by photoperiod(GO:0043153) |
0.3 | 1.3 | GO:0035426 | extracellular matrix-cell signaling(GO:0035426) |
0.3 | 1.6 | GO:0032439 | endosome localization(GO:0032439) |
0.2 | 1.1 | GO:0072383 | plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386) |
0.2 | 0.8 | GO:0015744 | succinate transport(GO:0015744) |
0.2 | 0.6 | GO:0032696 | negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899) |
0.2 | 0.6 | GO:0034184 | positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184) |
0.2 | 0.6 | GO:0030208 | dermatan sulfate biosynthetic process(GO:0030208) |
0.2 | 0.9 | GO:0031133 | cellular magnesium ion homeostasis(GO:0010961) regulation of axon diameter(GO:0031133) |
0.2 | 1.7 | GO:0042487 | regulation of odontogenesis of dentin-containing tooth(GO:0042487) |
0.2 | 2.2 | GO:0007042 | lysosomal lumen acidification(GO:0007042) |
0.2 | 3.1 | GO:0045723 | positive regulation of fatty acid biosynthetic process(GO:0045723) |
0.2 | 0.9 | GO:0003376 | sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520) |
0.2 | 1.0 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
0.2 | 1.2 | GO:0007569 | cell aging(GO:0007569) |
0.1 | 2.0 | GO:0061158 | 3'-UTR-mediated mRNA destabilization(GO:0061158) |
0.1 | 0.5 | GO:2000256 | endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163) positive regulation of male germ cell proliferation(GO:2000256) |
0.1 | 0.6 | GO:1903361 | protein localization to basolateral plasma membrane(GO:1903361) |
0.1 | 0.4 | GO:0021529 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) |
0.1 | 0.7 | GO:0043654 | recognition of apoptotic cell(GO:0043654) |
0.1 | 1.0 | GO:0006560 | proline metabolic process(GO:0006560) |
0.1 | 0.8 | GO:0046549 | phenol-containing compound catabolic process(GO:0019336) retinal cone cell development(GO:0046549) |
0.1 | 2.1 | GO:0003334 | keratinocyte development(GO:0003334) |
0.1 | 0.3 | GO:0043456 | regulation of pentose-phosphate shunt(GO:0043456) |
0.1 | 0.4 | GO:0033762 | response to glucagon(GO:0033762) |
0.1 | 0.4 | GO:0036006 | response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006) |
0.1 | 0.3 | GO:0070650 | actin filament bundle distribution(GO:0070650) |
0.1 | 1.2 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) |
0.1 | 1.3 | GO:0060707 | trophoblast giant cell differentiation(GO:0060707) |
0.1 | 0.5 | GO:0006072 | glycerol-3-phosphate metabolic process(GO:0006072) |
0.1 | 1.3 | GO:0033327 | Leydig cell differentiation(GO:0033327) |
0.1 | 2.2 | GO:0010883 | regulation of lipid storage(GO:0010883) |
0.1 | 0.6 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
0.1 | 1.8 | GO:0045780 | positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852) |
0.1 | 0.6 | GO:0016576 | histone dephosphorylation(GO:0016576) |
0.1 | 0.4 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
0.1 | 2.0 | GO:0045216 | cell-cell junction organization(GO:0045216) |
0.1 | 0.3 | GO:0060830 | ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) |
0.1 | 0.4 | GO:0030263 | apoptotic chromosome condensation(GO:0030263) |
0.1 | 1.5 | GO:0043277 | apoptotic cell clearance(GO:0043277) |
0.1 | 3.8 | GO:0048747 | muscle fiber development(GO:0048747) |
0.1 | 0.2 | GO:1905034 | regulation of antifungal innate immune response(GO:1905034) negative regulation of antifungal innate immune response(GO:1905035) |
0.1 | 0.5 | GO:0061084 | regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084) |
0.1 | 0.2 | GO:0090370 | negative regulation of cholesterol efflux(GO:0090370) |
0.1 | 0.3 | GO:1990839 | response to endothelin(GO:1990839) |
0.1 | 0.2 | GO:0098928 | presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526) |
0.1 | 0.7 | GO:0072600 | establishment of protein localization to Golgi(GO:0072600) |
0.1 | 1.1 | GO:0032402 | melanosome transport(GO:0032402) anagen(GO:0042640) |
0.1 | 1.5 | GO:0030866 | cortical actin cytoskeleton organization(GO:0030866) |
0.0 | 1.5 | GO:0046827 | positive regulation of protein export from nucleus(GO:0046827) |
0.0 | 0.4 | GO:0061525 | hindgut development(GO:0061525) |
0.0 | 0.5 | GO:0034551 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033) |
0.0 | 0.9 | GO:0032460 | negative regulation of protein oligomerization(GO:0032460) negative regulation of protein homooligomerization(GO:0032463) |
0.0 | 0.4 | GO:0006362 | transcription elongation from RNA polymerase I promoter(GO:0006362) |
0.0 | 0.2 | GO:0015015 | heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015) |
0.0 | 1.4 | GO:0045880 | positive regulation of smoothened signaling pathway(GO:0045880) |
0.0 | 0.2 | GO:0051024 | positive regulation of immunoglobulin secretion(GO:0051024) |
0.0 | 4.7 | GO:0010466 | negative regulation of peptidase activity(GO:0010466) |
0.0 | 0.3 | GO:0032836 | glomerular basement membrane development(GO:0032836) |
0.0 | 0.3 | GO:0001711 | endodermal cell fate commitment(GO:0001711) |
0.0 | 2.3 | GO:0032526 | response to retinoic acid(GO:0032526) |
0.0 | 0.1 | GO:0043328 | protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) |
0.0 | 1.1 | GO:0045737 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) |
0.0 | 0.2 | GO:0019673 | GDP-mannose metabolic process(GO:0019673) |
0.0 | 0.2 | GO:0048711 | positive regulation of astrocyte differentiation(GO:0048711) |
0.0 | 0.4 | GO:0016197 | endosomal transport(GO:0016197) |
0.0 | 0.5 | GO:0071347 | cellular response to interleukin-1(GO:0071347) |
0.0 | 0.2 | GO:0001731 | formation of translation preinitiation complex(GO:0001731) |
0.0 | 0.2 | GO:0015868 | purine ribonucleotide transport(GO:0015868) |
0.0 | 0.2 | GO:0000963 | mitochondrial RNA processing(GO:0000963) |
0.0 | 0.4 | GO:0035036 | binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) |
0.0 | 1.5 | GO:0007043 | cell-cell junction assembly(GO:0007043) |
0.0 | 0.3 | GO:0000338 | protein deneddylation(GO:0000338) |
0.0 | 1.6 | GO:0008584 | male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546) |
0.0 | 0.9 | GO:0086010 | membrane depolarization during action potential(GO:0086010) |
0.0 | 0.6 | GO:0000154 | rRNA modification(GO:0000154) |
0.0 | 0.1 | GO:0045541 | negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206) |
0.0 | 0.1 | GO:0050716 | regulation of interleukin-1 secretion(GO:0050704) regulation of interleukin-1 beta secretion(GO:0050706) positive regulation of interleukin-1 secretion(GO:0050716) positive regulation of interleukin-1 beta secretion(GO:0050718) |
0.0 | 2.9 | GO:0019221 | cytokine-mediated signaling pathway(GO:0019221) |
0.0 | 0.2 | GO:0021854 | hypothalamus development(GO:0021854) |
0.0 | 1.5 | GO:0042742 | defense response to bacterium(GO:0042742) |
0.0 | 0.4 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
0.0 | 0.3 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
0.0 | 0.1 | GO:0090435 | protein localization to nuclear envelope(GO:0090435) |
0.0 | 0.5 | GO:0043087 | regulation of GTPase activity(GO:0043087) |
0.0 | 0.1 | GO:0018026 | peptidyl-lysine monomethylation(GO:0018026) |
0.0 | 0.2 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 3.7 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
0.5 | 3.0 | GO:0030062 | mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062) |
0.4 | 4.3 | GO:0005915 | zonula adherens(GO:0005915) |
0.3 | 1.7 | GO:0030314 | junctional membrane complex(GO:0030314) |
0.3 | 1.6 | GO:0031523 | Myb complex(GO:0031523) |
0.3 | 1.9 | GO:0005859 | muscle myosin complex(GO:0005859) |
0.3 | 0.9 | GO:0044299 | C-fiber(GO:0044299) |
0.3 | 1.6 | GO:0045179 | apical cortex(GO:0045179) |
0.2 | 5.0 | GO:0031616 | spindle pole centrosome(GO:0031616) |
0.2 | 1.0 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
0.1 | 0.6 | GO:0097651 | phosphatidylinositol 3-kinase complex, class I(GO:0097651) |
0.1 | 0.9 | GO:0005775 | vacuolar lumen(GO:0005775) |
0.1 | 0.5 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
0.1 | 1.7 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
0.1 | 1.1 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
0.1 | 0.4 | GO:0001674 | female germ cell nucleus(GO:0001674) |
0.1 | 0.6 | GO:0005964 | phosphorylase kinase complex(GO:0005964) |
0.1 | 0.6 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
0.1 | 0.6 | GO:0030915 | Smc5-Smc6 complex(GO:0030915) |
0.1 | 4.6 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
0.1 | 5.7 | GO:0005581 | collagen trimer(GO:0005581) |
0.1 | 4.2 | GO:0005871 | kinesin complex(GO:0005871) |
0.1 | 5.3 | GO:0016528 | sarcoplasm(GO:0016528) |
0.1 | 0.3 | GO:0032280 | symmetric synapse(GO:0032280) |
0.1 | 2.8 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
0.1 | 0.6 | GO:1990907 | beta-catenin-TCF complex(GO:1990907) |
0.0 | 0.4 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
0.0 | 0.3 | GO:0097513 | myosin II filament(GO:0097513) |
0.0 | 0.4 | GO:0061574 | ASAP complex(GO:0061574) |
0.0 | 0.3 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
0.0 | 0.6 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
0.0 | 3.0 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
0.0 | 0.1 | GO:0000814 | ESCRT II complex(GO:0000814) |
0.0 | 0.2 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
0.0 | 1.9 | GO:0031519 | PcG protein complex(GO:0031519) |
0.0 | 0.5 | GO:0032433 | filopodium tip(GO:0032433) |
0.0 | 0.3 | GO:1990635 | proximal dendrite(GO:1990635) |
0.0 | 0.2 | GO:0016580 | Sin3 complex(GO:0016580) |
0.0 | 1.5 | GO:0005884 | actin filament(GO:0005884) |
0.0 | 0.2 | GO:0035749 | myelin sheath adaxonal region(GO:0035749) |
0.0 | 9.1 | GO:0005667 | transcription factor complex(GO:0005667) |
0.0 | 2.0 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
0.0 | 0.4 | GO:0097228 | sperm midpiece(GO:0097225) sperm principal piece(GO:0097228) |
0.0 | 0.8 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
0.0 | 2.3 | GO:0005923 | bicellular tight junction(GO:0005923) |
0.0 | 0.0 | GO:0043541 | UDP-N-acetylglucosamine transferase complex(GO:0043541) |
0.0 | 0.4 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
0.0 | 0.2 | GO:0005614 | interstitial matrix(GO:0005614) |
0.0 | 0.7 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
0.0 | 0.4 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
0.0 | 0.2 | GO:0005922 | connexon complex(GO:0005922) |
0.0 | 0.5 | GO:0016234 | inclusion body(GO:0016234) |
0.0 | 2.5 | GO:0008021 | synaptic vesicle(GO:0008021) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.4 | 8.2 | GO:0043426 | MRF binding(GO:0043426) |
1.0 | 3.0 | GO:0004774 | succinate-CoA ligase activity(GO:0004774) |
0.9 | 4.7 | GO:0019828 | aspartic-type endopeptidase inhibitor activity(GO:0019828) |
0.7 | 3.0 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
0.4 | 1.6 | GO:0034988 | Fc-gamma receptor I complex binding(GO:0034988) |
0.4 | 1.5 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
0.4 | 1.9 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
0.3 | 4.9 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
0.3 | 3.8 | GO:0001618 | virus receptor activity(GO:0001618) |
0.3 | 1.1 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
0.3 | 0.8 | GO:0015140 | malate transmembrane transporter activity(GO:0015140) |
0.3 | 3.3 | GO:0001972 | retinoic acid binding(GO:0001972) |
0.2 | 0.5 | GO:0016901 | glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901) |
0.2 | 4.2 | GO:0030506 | ankyrin binding(GO:0030506) |
0.2 | 1.9 | GO:0070097 | delta-catenin binding(GO:0070097) |
0.2 | 2.0 | GO:0019956 | chemokine binding(GO:0019956) |
0.1 | 1.3 | GO:0043237 | laminin-1 binding(GO:0043237) |
0.1 | 0.6 | GO:0001537 | N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537) |
0.1 | 0.7 | GO:0070815 | peptidyl-lysine 5-dioxygenase activity(GO:0070815) |
0.1 | 3.4 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.1 | 5.1 | GO:0070412 | R-SMAD binding(GO:0070412) |
0.1 | 1.5 | GO:0005522 | profilin binding(GO:0005522) |
0.1 | 0.9 | GO:0038036 | sphingosine-1-phosphate receptor activity(GO:0038036) |
0.1 | 0.3 | GO:0046538 | bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538) |
0.1 | 0.8 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
0.1 | 2.1 | GO:0042056 | chemoattractant activity(GO:0042056) |
0.1 | 0.5 | GO:0008427 | calcium-dependent protein kinase inhibitor activity(GO:0008427) |
0.1 | 0.6 | GO:0030284 | estrogen receptor activity(GO:0030284) |
0.1 | 0.6 | GO:1990829 | C-rich single-stranded DNA binding(GO:1990829) |
0.1 | 0.6 | GO:0004689 | phosphorylase kinase activity(GO:0004689) |
0.1 | 0.3 | GO:0034437 | glycoprotein transporter activity(GO:0034437) |
0.1 | 0.6 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
0.1 | 1.4 | GO:0016864 | protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864) |
0.1 | 0.3 | GO:0048408 | epidermal growth factor binding(GO:0048408) |
0.1 | 0.4 | GO:0001165 | RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165) |
0.1 | 0.9 | GO:0005537 | mannose binding(GO:0005537) |
0.1 | 1.7 | GO:0008307 | structural constituent of muscle(GO:0008307) |
0.1 | 0.6 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
0.1 | 0.2 | GO:0033592 | RNA strand annealing activity(GO:0033592) |
0.1 | 4.2 | GO:0003777 | microtubule motor activity(GO:0003777) |
0.1 | 0.4 | GO:0048101 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
0.1 | 0.2 | GO:0017095 | heparan sulfate 6-O-sulfotransferase activity(GO:0017095) |
0.1 | 1.8 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
0.0 | 0.3 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
0.0 | 0.1 | GO:0019966 | interleukin-1 binding(GO:0019966) |
0.0 | 1.0 | GO:0071949 | FAD binding(GO:0071949) |
0.0 | 1.0 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
0.0 | 1.3 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
0.0 | 1.4 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
0.0 | 0.2 | GO:0004645 | phosphorylase activity(GO:0004645) |
0.0 | 0.9 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
0.0 | 2.0 | GO:0003774 | motor activity(GO:0003774) |
0.0 | 0.6 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
0.0 | 0.9 | GO:0005248 | voltage-gated sodium channel activity(GO:0005248) |
0.0 | 0.4 | GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
0.0 | 0.2 | GO:0033691 | sialic acid binding(GO:0033691) |
0.0 | 0.6 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.0 | 1.9 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
0.0 | 5.1 | GO:0001047 | core promoter binding(GO:0001047) |
0.0 | 0.2 | GO:0016618 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
0.0 | 0.6 | GO:0019789 | SUMO transferase activity(GO:0019789) |
0.0 | 5.6 | GO:0008022 | protein C-terminus binding(GO:0008022) |
0.0 | 1.7 | GO:0019888 | protein phosphatase regulator activity(GO:0019888) |
0.0 | 0.2 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
0.0 | 0.1 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
0.0 | 0.3 | GO:0050811 | GABA receptor binding(GO:0050811) |
0.0 | 0.2 | GO:0005243 | gap junction channel activity(GO:0005243) |
0.0 | 0.2 | GO:0001222 | transcription corepressor binding(GO:0001222) |
0.0 | 6.2 | GO:0001159 | core promoter proximal region DNA binding(GO:0001159) |
0.0 | 0.3 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
0.0 | 6.2 | GO:0005198 | structural molecule activity(GO:0005198) |
0.0 | 0.2 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
0.0 | 0.4 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
0.0 | 0.4 | GO:0051059 | NF-kappaB binding(GO:0051059) |
0.0 | 0.2 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 8.2 | PID_CIRCADIAN_PATHWAY | Circadian rhythm pathway |
0.3 | 4.7 | SA_REG_CASCADE_OF_CYCLIN_EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
0.3 | 3.5 | PID_VEGF_VEGFR_PATHWAY | VEGF and VEGFR signaling network |
0.2 | 6.8 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
0.1 | 2.9 | PID_IL27_PATHWAY | IL27-mediated signaling events |
0.1 | 5.8 | SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES | Genes related to regulation of the actin cytoskeleton |
0.1 | 4.0 | PID_IL2_STAT5_PATHWAY | IL2 signaling events mediated by STAT5 |
0.1 | 4.4 | PID_ECADHERIN_STABILIZATION_PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
0.1 | 0.7 | PID_TCR_RAS_PATHWAY | Ras signaling in the CD4+ TCR pathway |
0.1 | 1.8 | PID_EPHRINB_REV_PATHWAY | Ephrin B reverse signaling |
0.1 | 2.3 | PID_IL4_2PATHWAY | IL4-mediated signaling events |
0.1 | 1.8 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
0.1 | 1.9 | PID_RXR_VDR_PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
0.0 | 0.9 | PID_S1P_S1P2_PATHWAY | S1P2 pathway |
0.0 | 1.5 | PID_INSULIN_GLUCOSE_PATHWAY | Insulin-mediated glucose transport |
0.0 | 1.2 | PID_FOXM1_PATHWAY | FOXM1 transcription factor network |
0.0 | 2.1 | PID_E2F_PATHWAY | E2F transcription factor network |
0.0 | 0.6 | SIG_CHEMOTAXIS | Genes related to chemotaxis |
0.0 | 1.0 | PID_FCER1_PATHWAY | Fc-epsilon receptor I signaling in mast cells |
0.0 | 1.7 | PID_AR_PATHWAY | Coregulation of Androgen receptor activity |
0.0 | 1.4 | PID_NOTCH_PATHWAY | Notch signaling pathway |
0.0 | 0.2 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 3.5 | REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
0.3 | 11.6 | REACTOME_G1_PHASE | Genes involved in G1 Phase |
0.2 | 6.2 | REACTOME_TIGHT_JUNCTION_INTERACTIONS | Genes involved in Tight junction interactions |
0.2 | 1.8 | REACTOME_KERATAN_SULFATE_DEGRADATION | Genes involved in Keratan sulfate degradation |
0.2 | 4.9 | REACTOME_KINESINS | Genes involved in Kinesins |
0.2 | 7.9 | REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
0.2 | 4.2 | REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
0.1 | 3.0 | REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
0.1 | 1.7 | REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
0.1 | 0.8 | REACTOME_AMINE_DERIVED_HORMONES | Genes involved in Amine-derived hormones |
0.1 | 2.1 | REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN | Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein |
0.1 | 2.2 | REACTOME_LYSOSOME_VESICLE_BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
0.1 | 1.8 | REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
0.0 | 1.2 | REACTOME_SULFUR_AMINO_ACID_METABOLISM | Genes involved in Sulfur amino acid metabolism |
0.0 | 0.7 | REACTOME_RAF_MAP_KINASE_CASCADE | Genes involved in RAF/MAP kinase cascade |
0.0 | 2.1 | REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
0.0 | 0.6 | REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS | Genes involved in Viral Messenger RNA Synthesis |
0.0 | 2.1 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
0.0 | 0.3 | REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING | Genes involved in SHC1 events in EGFR signaling |
0.0 | 0.2 | REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING | Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling |
0.0 | 0.6 | REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
0.0 | 1.2 | REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
0.0 | 1.4 | REACTOME_NETRIN1_SIGNALING | Genes involved in Netrin-1 signaling |
0.0 | 0.2 | REACTOME_MTORC1_MEDIATED_SIGNALLING | Genes involved in mTORC1-mediated signalling |
0.0 | 0.3 | REACTOME_HDL_MEDIATED_LIPID_TRANSPORT | Genes involved in HDL-mediated lipid transport |
0.0 | 0.7 | REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
0.0 | 0.6 | REACTOME_GLYCOSPHINGOLIPID_METABOLISM | Genes involved in Glycosphingolipid metabolism |
0.0 | 0.6 | REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA | Genes involved in G beta:gamma signalling through PI3Kgamma |
0.0 | 0.4 | REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION | Genes involved in RNA Polymerase I Transcription Termination |
0.0 | 0.4 | REACTOME_CGMP_EFFECTS | Genes involved in cGMP effects |
0.0 | 0.2 | REACTOME_GAP_JUNCTION_ASSEMBLY | Genes involved in Gap junction assembly |
0.0 | 0.4 | REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS | Genes involved in Regulation of gene expression in beta cells |
0.0 | 0.4 | REACTOME_MRNA_SPLICING_MINOR_PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
0.0 | 0.6 | REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM | Genes involved in Chondroitin sulfate/dermatan sulfate metabolism |