Motif ID: Ehf

Z-value: 0.285


Transcription factors associated with Ehf:

Gene SymbolEntrez IDGene Name
Ehf ENSMUSG00000012350.9 Ehf



Activity profile for motif Ehf.

activity profile for motif Ehf


Sorted Z-values histogram for motif Ehf

Sorted Z-values for motif Ehf



Network of associatons between targets according to the STRING database.



First level regulatory network of Ehf

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_48049080 0.777 ENSMUST00000153369.1
Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr15_+_4375462 0.685 ENSMUST00000061925.4
Plcxd3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr11_-_54860564 0.609 ENSMUST00000144164.1
Lyrm7
LYR motif containing 7
chr18_+_37477768 0.558 ENSMUST00000051442.5
Pcdhb16
protocadherin beta 16
chr13_+_109260481 0.529 ENSMUST00000153234.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr3_+_28781305 0.453 ENSMUST00000060500.7
Eif5a2
eukaryotic translation initiation factor 5A2
chr11_+_70764209 0.433 ENSMUST00000060444.5
Zfp3
zinc finger protein 3
chr1_+_146495621 0.366 ENSMUST00000074622.4
Brinp3
bone morphogenetic protein/retinoic acid inducible neural specific 3
chr9_+_32116040 0.358 ENSMUST00000174641.1
Arhgap32
Rho GTPase activating protein 32
chrX_+_71663665 0.333 ENSMUST00000070449.5
Gpr50
G-protein-coupled receptor 50
chr3_+_116594959 0.320 ENSMUST00000029571.8
Sass6
spindle assembly 6 homolog (C. elegans)
chr11_+_72689997 0.307 ENSMUST00000155998.1
Ankfy1
ankyrin repeat and FYVE domain containing 1
chr2_+_164805082 0.281 ENSMUST00000052107.4
Zswim3
zinc finger SWIM-type containing 3
chr9_-_107541816 0.267 ENSMUST00000041459.3
Cyb561d2
cytochrome b-561 domain containing 2
chr15_+_41830921 0.256 ENSMUST00000166917.1
Oxr1
oxidation resistance 1
chr6_+_142413441 0.223 ENSMUST00000088263.4
B230216G23Rik
RIKEN cDNA B230216G23 gene
chr4_-_120815703 0.222 ENSMUST00000120779.1
Nfyc
nuclear transcription factor-Y gamma
chr13_-_8870999 0.221 ENSMUST00000177404.1
ENSMUST00000176922.1
ENSMUST00000021572.4
Wdr37


WD repeat domain 37


chr18_-_24603791 0.203 ENSMUST00000070726.3
Slc39a6
solute carrier family 39 (metal ion transporter), member 6
chr6_+_142414012 0.202 ENSMUST00000141548.1
B230216G23Rik
RIKEN cDNA B230216G23 gene
chr9_+_107542209 0.164 ENSMUST00000010201.3
Nprl2
nitrogen permease regulator-like 2
chr5_+_121749196 0.163 ENSMUST00000161064.1
Atxn2
ataxin 2
chr13_-_8870967 0.157 ENSMUST00000164183.2
Wdr37
WD repeat domain 37
chr6_-_30915552 0.144 ENSMUST00000048580.1
Tsga13
testis specific gene A13
chr18_-_24603464 0.124 ENSMUST00000154205.1
Slc39a6
solute carrier family 39 (metal ion transporter), member 6
chr16_-_45844228 0.080 ENSMUST00000076333.5
Phldb2
pleckstrin homology-like domain, family B, member 2
chr8_-_104641666 0.078 ENSMUST00000093234.4
Fam96b
family with sequence similarity 96, member B
chr16_-_45844303 0.071 ENSMUST00000036355.6
Phldb2
pleckstrin homology-like domain, family B, member 2
chr1_+_127868773 0.064 ENSMUST00000037649.5
Rab3gap1
RAB3 GTPase activating protein subunit 1
chr9_-_106447584 0.052 ENSMUST00000171678.1
ENSMUST00000048685.6
ENSMUST00000171925.1
Abhd14a


abhydrolase domain containing 14A


chr5_+_90794530 0.042 ENSMUST00000031322.6
Cxcl15
chemokine (C-X-C motif) ligand 15
chr6_+_142413833 0.028 ENSMUST00000126521.2
B230216G23Rik
RIKEN cDNA B230216G23 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
0.1 0.5 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.6 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.3 GO:0032439 endosome localization(GO:0032439) positive regulation of pinocytosis(GO:0048549)
0.0 0.5 GO:1901898 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.1 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.2 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.4 GO:0000470 maturation of LSU-rRNA(GO:0000470)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0098536 deuterosome(GO:0098536)
0.0 0.3 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.4 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.3 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.1 GO:0097361 CIA complex(GO:0097361)
0.0 0.6 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.8 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 ST_GA12_PATHWAY G alpha 12 Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.5 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.5 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.8 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway