Motif ID: Sox8
Z-value: 0.393

Transcription factors associated with Sox8:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Sox8 | ENSMUSG00000024176.4 | Sox8 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Sox8 | mm10_v2_chr17_-_25570678_25570694 | -0.47 | 1.8e-03 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 2.4 | GO:2000820 | negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820) |
0.3 | 1.0 | GO:1904565 | response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566) |
0.2 | 1.2 | GO:0060467 | negative regulation of fertilization(GO:0060467) |
0.2 | 2.1 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
0.2 | 0.6 | GO:2000659 | regulation of interleukin-1-mediated signaling pathway(GO:2000659) |
0.1 | 1.3 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
0.1 | 2.1 | GO:0007617 | mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705) |
0.0 | 0.6 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
0.0 | 0.1 | GO:0001951 | intestinal D-glucose absorption(GO:0001951) terminal web assembly(GO:1902896) |
0.0 | 0.1 | GO:2001184 | regulation of interleukin-12 secretion(GO:2001182) positive regulation of interleukin-12 secretion(GO:2001184) |
0.0 | 0.1 | GO:1903026 | negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026) |
0.0 | 0.3 | GO:2001256 | regulation of store-operated calcium entry(GO:2001256) |
0.0 | 1.5 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
0.0 | 0.5 | GO:0003333 | amino acid transmembrane transport(GO:0003333) |
0.0 | 0.5 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
0.0 | 0.5 | GO:0007099 | centriole replication(GO:0007099) |
0.0 | 0.0 | GO:0033092 | positive regulation of immature T cell proliferation in thymus(GO:0033092) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 2.1 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
0.1 | 0.5 | GO:0071942 | XPC complex(GO:0071942) |
0.1 | 1.3 | GO:0097225 | sperm midpiece(GO:0097225) |
0.1 | 1.1 | GO:0044232 | organelle membrane contact site(GO:0044232) |
0.0 | 0.5 | GO:0017119 | Golgi transport complex(GO:0017119) |
0.0 | 0.1 | GO:1990357 | terminal web(GO:1990357) |
0.0 | 0.3 | GO:0010369 | chromocenter(GO:0010369) |
0.0 | 1.2 | GO:0001669 | acrosomal vesicle(GO:0001669) |
0.0 | 1.3 | GO:0043198 | dendritic shaft(GO:0043198) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 2.4 | GO:0035939 | microsatellite binding(GO:0035939) |
0.4 | 2.1 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
0.2 | 0.6 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
0.1 | 1.0 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915) |
0.1 | 0.4 | GO:0033883 | pyridoxal phosphatase activity(GO:0033883) |
0.1 | 1.3 | GO:0050811 | GABA receptor binding(GO:0050811) |
0.1 | 0.5 | GO:0032795 | heterotrimeric G-protein binding(GO:0032795) |
0.0 | 2.1 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
0.0 | 0.3 | GO:0031802 | type 5 metabotropic glutamate receptor binding(GO:0031802) |
0.0 | 1.2 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.0 | 1.1 | GO:0015485 | cholesterol binding(GO:0015485) |
0.0 | 0.1 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 2.4 | PID_HES_HEY_PATHWAY | Notch-mediated HES/HEY network |
0.0 | 2.1 | PID_HIF1_TFPATHWAY | HIF-1-alpha transcription factor network |
0.0 | 0.8 | PID_AURORA_B_PATHWAY | Aurora B signaling |
0.0 | 0.6 | ST_JNK_MAPK_PATHWAY | JNK MAPK Pathway |
0.0 | 1.0 | PID_LYSOPHOSPHOLIPID_PATHWAY | LPA receptor mediated events |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.8 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
0.1 | 2.1 | REACTOME_GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
0.0 | 0.6 | REACTOME_ERKS_ARE_INACTIVATED | Genes involved in ERKs are inactivated |
0.0 | 2.4 | REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
0.0 | 0.5 | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |