Motif ID: Hes1
Z-value: 1.529

Transcription factors associated with Hes1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Hes1 | ENSMUSG00000022528.7 | Hes1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Hes1 | mm10_v2_chr16_+_30065333_30065351 | 0.61 | 2.6e-05 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
6.6 | 59.6 | GO:0070874 | negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874) |
3.9 | 15.5 | GO:1904565 | response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566) |
3.3 | 13.2 | GO:2000313 | fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) |
3.1 | 12.4 | GO:2000048 | negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048) |
2.5 | 10.2 | GO:2000974 | negative regulation of pro-B cell differentiation(GO:2000974) |
2.4 | 9.6 | GO:0003360 | brainstem development(GO:0003360) |
1.8 | 5.4 | GO:0018298 | protein-chromophore linkage(GO:0018298) |
1.8 | 5.3 | GO:0003195 | tricuspid valve formation(GO:0003195) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) |
1.3 | 3.9 | GO:0060167 | regulation of adenosine receptor signaling pathway(GO:0060167) regulation of G-protein coupled receptor internalization(GO:1904020) |
1.3 | 6.3 | GO:1903609 | negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609) |
1.1 | 4.4 | GO:0006545 | glycine biosynthetic process(GO:0006545) |
1.0 | 2.9 | GO:2000501 | natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501) |
0.9 | 5.2 | GO:0035087 | siRNA loading onto RISC involved in RNA interference(GO:0035087) |
0.8 | 2.5 | GO:0014738 | regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900) |
0.8 | 4.1 | GO:0070197 | meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240) |
0.7 | 2.2 | GO:0060399 | positive regulation of growth hormone receptor signaling pathway(GO:0060399) |
0.7 | 5.0 | GO:0046549 | phenol-containing compound catabolic process(GO:0019336) retinal cone cell development(GO:0046549) |
0.7 | 3.3 | GO:0090521 | glomerular visceral epithelial cell migration(GO:0090521) |
0.6 | 3.1 | GO:0048133 | NK T cell differentiation(GO:0001865) germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138) germline stem cell asymmetric division(GO:0098728) |
0.6 | 2.5 | GO:0060032 | notochord regression(GO:0060032) |
0.6 | 3.1 | GO:2000255 | negative regulation of male germ cell proliferation(GO:2000255) |
0.6 | 1.8 | GO:0021577 | hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) |
0.6 | 2.4 | GO:0014722 | regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722) |
0.6 | 1.7 | GO:0006011 | UDP-glucose metabolic process(GO:0006011) glucose 1-phosphate metabolic process(GO:0019255) |
0.5 | 7.4 | GO:0007213 | G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) |
0.5 | 2.6 | GO:0051387 | negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387) |
0.5 | 3.1 | GO:0034587 | piRNA metabolic process(GO:0034587) |
0.5 | 1.5 | GO:0071707 | immunoglobulin heavy chain V-D-J recombination(GO:0071707) |
0.5 | 1.5 | GO:0033122 | regulation of purine nucleotide catabolic process(GO:0033121) negative regulation of purine nucleotide catabolic process(GO:0033122) regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344) |
0.5 | 3.8 | GO:0030174 | regulation of DNA-dependent DNA replication initiation(GO:0030174) |
0.5 | 4.2 | GO:0001842 | neural fold formation(GO:0001842) |
0.5 | 2.3 | GO:0072757 | cellular response to camptothecin(GO:0072757) |
0.4 | 2.6 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
0.4 | 4.3 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
0.4 | 1.3 | GO:0009174 | UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049) |
0.4 | 1.2 | GO:0002302 | CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) |
0.4 | 2.7 | GO:0089700 | protein kinase D signaling(GO:0089700) |
0.4 | 2.7 | GO:0019262 | N-acetylneuraminate catabolic process(GO:0019262) |
0.4 | 2.3 | GO:0042535 | positive regulation of tumor necrosis factor biosynthetic process(GO:0042535) macropinocytosis(GO:0044351) |
0.4 | 1.1 | GO:0000720 | pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) |
0.4 | 2.5 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
0.3 | 1.3 | GO:1903265 | positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265) |
0.3 | 1.9 | GO:0071394 | cellular response to testosterone stimulus(GO:0071394) |
0.3 | 1.5 | GO:0006680 | glucosylceramide catabolic process(GO:0006680) |
0.3 | 1.5 | GO:0045578 | negative regulation of B cell differentiation(GO:0045578) |
0.3 | 1.6 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
0.3 | 1.3 | GO:2001032 | regulation of double-strand break repair via nonhomologous end joining(GO:2001032) |
0.2 | 0.7 | GO:2000195 | negative regulation of female gonad development(GO:2000195) |
0.2 | 1.4 | GO:0006528 | asparagine metabolic process(GO:0006528) |
0.2 | 1.9 | GO:0043201 | response to leucine(GO:0043201) cellular response to leucine(GO:0071233) |
0.2 | 2.5 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
0.2 | 3.0 | GO:0007190 | activation of adenylate cyclase activity(GO:0007190) |
0.2 | 0.6 | GO:1905051 | regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053) |
0.2 | 3.2 | GO:0007220 | Notch receptor processing(GO:0007220) |
0.2 | 1.1 | GO:0070459 | prolactin secretion(GO:0070459) |
0.2 | 0.6 | GO:2000054 | regulation of chondrocyte development(GO:0061181) negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054) |
0.2 | 5.3 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
0.2 | 1.4 | GO:0006621 | protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437) |
0.2 | 0.6 | GO:1905223 | epicardium morphogenesis(GO:1905223) |
0.2 | 1.8 | GO:0061484 | hematopoietic stem cell homeostasis(GO:0061484) |
0.2 | 1.2 | GO:0015015 | heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015) |
0.2 | 1.9 | GO:0070940 | dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940) |
0.2 | 3.5 | GO:0045653 | negative regulation of megakaryocyte differentiation(GO:0045653) |
0.2 | 1.5 | GO:0007016 | cytoskeletal anchoring at plasma membrane(GO:0007016) |
0.2 | 0.5 | GO:0045617 | negative regulation of keratinocyte differentiation(GO:0045617) |
0.2 | 0.4 | GO:1990523 | bone regeneration(GO:1990523) |
0.2 | 0.7 | GO:0006776 | vitamin A metabolic process(GO:0006776) |
0.2 | 2.8 | GO:0000338 | protein deneddylation(GO:0000338) |
0.2 | 0.9 | GO:0044828 | negative regulation by host of viral genome replication(GO:0044828) |
0.2 | 3.3 | GO:0038092 | nodal signaling pathway(GO:0038092) |
0.2 | 1.1 | GO:0021913 | regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) |
0.1 | 1.0 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
0.1 | 1.4 | GO:0043568 | positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568) |
0.1 | 0.4 | GO:0014063 | negative regulation of serotonin secretion(GO:0014063) |
0.1 | 3.6 | GO:0035067 | negative regulation of histone acetylation(GO:0035067) |
0.1 | 0.5 | GO:1901301 | regulation of cargo loading into COPII-coated vesicle(GO:1901301) |
0.1 | 2.1 | GO:0045647 | negative regulation of erythrocyte differentiation(GO:0045647) |
0.1 | 3.2 | GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289) |
0.1 | 2.5 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
0.1 | 4.3 | GO:0009409 | response to cold(GO:0009409) |
0.1 | 0.4 | GO:0060468 | prevention of polyspermy(GO:0060468) |
0.1 | 2.9 | GO:0045672 | positive regulation of osteoclast differentiation(GO:0045672) |
0.1 | 4.8 | GO:0006879 | cellular iron ion homeostasis(GO:0006879) |
0.1 | 1.1 | GO:0045794 | negative regulation of cell volume(GO:0045794) |
0.1 | 0.3 | GO:0032241 | positive regulation of nucleobase-containing compound transport(GO:0032241) |
0.1 | 1.7 | GO:0035563 | positive regulation of chromatin binding(GO:0035563) |
0.1 | 2.9 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
0.1 | 0.5 | GO:0010993 | regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994) |
0.1 | 0.3 | GO:0071929 | alpha-tubulin acetylation(GO:0071929) |
0.1 | 0.2 | GO:0034392 | negative regulation of smooth muscle cell apoptotic process(GO:0034392) |
0.1 | 1.1 | GO:0006415 | translational termination(GO:0006415) |
0.1 | 0.9 | GO:0033182 | regulation of histone ubiquitination(GO:0033182) |
0.1 | 3.1 | GO:0030513 | positive regulation of BMP signaling pathway(GO:0030513) |
0.1 | 1.2 | GO:0034143 | regulation of toll-like receptor 4 signaling pathway(GO:0034143) |
0.1 | 0.5 | GO:0075525 | viral translational termination-reinitiation(GO:0075525) |
0.1 | 1.5 | GO:0030574 | collagen catabolic process(GO:0030574) |
0.1 | 2.7 | GO:0042149 | cellular response to glucose starvation(GO:0042149) |
0.1 | 0.6 | GO:0006105 | succinate metabolic process(GO:0006105) |
0.1 | 2.1 | GO:0071260 | cellular response to mechanical stimulus(GO:0071260) |
0.1 | 0.4 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
0.1 | 0.5 | GO:0035873 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879) |
0.1 | 5.1 | GO:0051384 | response to glucocorticoid(GO:0051384) |
0.1 | 0.9 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
0.1 | 1.4 | GO:0031065 | positive regulation of histone deacetylation(GO:0031065) |
0.1 | 3.0 | GO:0021591 | ventricular system development(GO:0021591) |
0.1 | 0.4 | GO:0007603 | phototransduction, visible light(GO:0007603) |
0.1 | 1.1 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
0.1 | 8.1 | GO:0050772 | positive regulation of axonogenesis(GO:0050772) |
0.1 | 1.0 | GO:0097034 | mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034) |
0.1 | 0.6 | GO:0075522 | IRES-dependent viral translational initiation(GO:0075522) |
0.1 | 0.8 | GO:0006107 | oxaloacetate metabolic process(GO:0006107) |
0.1 | 1.3 | GO:2001273 | regulation of glucose import in response to insulin stimulus(GO:2001273) |
0.1 | 2.8 | GO:0060325 | face morphogenesis(GO:0060325) |
0.1 | 0.6 | GO:0090084 | negative regulation of inclusion body assembly(GO:0090084) |
0.1 | 0.8 | GO:0090308 | regulation of methylation-dependent chromatin silencing(GO:0090308) |
0.1 | 1.5 | GO:0045776 | negative regulation of blood pressure(GO:0045776) |
0.1 | 0.2 | GO:0061198 | response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984) fungiform papilla formation(GO:0061198) |
0.0 | 1.2 | GO:0007020 | microtubule nucleation(GO:0007020) |
0.0 | 0.5 | GO:0006515 | misfolded or incompletely synthesized protein catabolic process(GO:0006515) |
0.0 | 2.8 | GO:0006661 | phosphatidylinositol biosynthetic process(GO:0006661) |
0.0 | 0.9 | GO:1990126 | retrograde transport, endosome to plasma membrane(GO:1990126) |
0.0 | 0.1 | GO:0043686 | co-translational protein modification(GO:0043686) |
0.0 | 0.3 | GO:0045583 | regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585) |
0.0 | 0.1 | GO:0071287 | cellular response to manganese ion(GO:0071287) |
0.0 | 0.6 | GO:0034453 | microtubule anchoring(GO:0034453) |
0.0 | 0.4 | GO:0043586 | tongue development(GO:0043586) |
0.0 | 1.0 | GO:0030252 | growth hormone secretion(GO:0030252) |
0.0 | 2.0 | GO:0007019 | microtubule depolymerization(GO:0007019) |
0.0 | 2.2 | GO:0051291 | protein heterooligomerization(GO:0051291) |
0.0 | 0.7 | GO:0002446 | neutrophil mediated immunity(GO:0002446) |
0.0 | 1.6 | GO:0002181 | cytoplasmic translation(GO:0002181) |
0.0 | 0.4 | GO:0090435 | protein localization to nuclear envelope(GO:0090435) |
0.0 | 1.4 | GO:0009261 | purine ribonucleotide catabolic process(GO:0009154) ribonucleotide catabolic process(GO:0009261) |
0.0 | 0.2 | GO:0072643 | interferon-gamma secretion(GO:0072643) |
0.0 | 0.0 | GO:1902416 | positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216) |
0.0 | 1.0 | GO:0006414 | translational elongation(GO:0006414) |
0.0 | 0.1 | GO:0002756 | MyD88-independent toll-like receptor signaling pathway(GO:0002756) |
0.0 | 0.4 | GO:0007608 | sensory perception of smell(GO:0007608) |
0.0 | 1.4 | GO:0033045 | regulation of sister chromatid segregation(GO:0033045) |
0.0 | 0.5 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
0.0 | 0.8 | GO:0019228 | neuronal action potential(GO:0019228) |
0.0 | 0.8 | GO:0031648 | protein destabilization(GO:0031648) |
0.0 | 2.0 | GO:0045089 | positive regulation of innate immune response(GO:0045089) |
0.0 | 3.4 | GO:0007411 | axon guidance(GO:0007411) |
0.0 | 0.1 | GO:2000491 | positive regulation of hepatic stellate cell activation(GO:2000491) |
0.0 | 1.7 | GO:0006626 | protein targeting to mitochondrion(GO:0006626) |
0.0 | 0.6 | GO:0018279 | protein N-linked glycosylation via asparagine(GO:0018279) |
0.0 | 0.9 | GO:0030307 | positive regulation of cell growth(GO:0030307) |
0.0 | 1.1 | GO:0048024 | regulation of mRNA splicing, via spliceosome(GO:0048024) |
0.0 | 0.2 | GO:0051016 | barbed-end actin filament capping(GO:0051016) |
0.0 | 0.7 | GO:0045665 | negative regulation of neuron differentiation(GO:0045665) |
0.0 | 0.2 | GO:0006406 | mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.2 | 9.6 | GO:0097059 | CNTFR-CLCF1 complex(GO:0097059) |
0.8 | 3.3 | GO:0090537 | CERF complex(GO:0090537) |
0.7 | 3.3 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
0.6 | 3.8 | GO:0000235 | astral microtubule(GO:0000235) |
0.6 | 3.3 | GO:0000214 | tRNA-intron endonuclease complex(GO:0000214) |
0.5 | 6.3 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
0.5 | 4.3 | GO:0031254 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
0.4 | 1.3 | GO:0097057 | TRAF2-GSTP1 complex(GO:0097057) |
0.4 | 1.9 | GO:1990131 | Gtr1-Gtr2 GTPase complex(GO:1990131) |
0.3 | 1.0 | GO:0035061 | interchromatin granule(GO:0035061) |
0.3 | 0.9 | GO:0031372 | UBC13-MMS2 complex(GO:0031372) |
0.3 | 4.3 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
0.3 | 5.5 | GO:0016580 | Sin3 complex(GO:0016580) |
0.3 | 4.1 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
0.2 | 2.6 | GO:0005642 | annulate lamellae(GO:0005642) |
0.2 | 3.0 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
0.2 | 0.9 | GO:0030906 | retromer, cargo-selective complex(GO:0030906) |
0.2 | 1.1 | GO:0034715 | pICln-Sm protein complex(GO:0034715) |
0.2 | 1.8 | GO:0070578 | RISC-loading complex(GO:0070578) |
0.2 | 2.2 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
0.2 | 0.8 | GO:0070552 | BRISC complex(GO:0070552) |
0.2 | 2.5 | GO:0097542 | ciliary tip(GO:0097542) |
0.2 | 7.4 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
0.2 | 1.0 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
0.2 | 3.5 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
0.2 | 2.8 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
0.1 | 0.6 | GO:0045283 | mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283) |
0.1 | 1.8 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
0.1 | 0.6 | GO:0099524 | region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524) |
0.1 | 1.3 | GO:0044754 | secondary lysosome(GO:0005767) autolysosome(GO:0044754) |
0.1 | 2.7 | GO:0000421 | autophagosome membrane(GO:0000421) |
0.1 | 2.4 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
0.1 | 2.1 | GO:0035102 | PRC1 complex(GO:0035102) |
0.1 | 2.3 | GO:0005682 | U5 snRNP(GO:0005682) |
0.1 | 16.9 | GO:0030139 | endocytic vesicle(GO:0030139) |
0.1 | 1.0 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
0.1 | 1.6 | GO:0042788 | polysomal ribosome(GO:0042788) |
0.1 | 3.5 | GO:0000788 | nuclear nucleosome(GO:0000788) |
0.1 | 1.5 | GO:0031011 | Ino80 complex(GO:0031011) |
0.1 | 0.2 | GO:0044194 | cytolytic granule(GO:0044194) |
0.1 | 0.4 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
0.1 | 1.7 | GO:0033276 | transcription factor TFTC complex(GO:0033276) |
0.1 | 3.5 | GO:0005719 | nuclear euchromatin(GO:0005719) |
0.1 | 1.3 | GO:0032156 | septin cytoskeleton(GO:0032156) |
0.1 | 2.8 | GO:0008180 | COP9 signalosome(GO:0008180) |
0.1 | 0.5 | GO:0005785 | signal recognition particle receptor complex(GO:0005785) |
0.1 | 2.4 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
0.1 | 0.5 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
0.1 | 0.7 | GO:0005838 | proteasome regulatory particle(GO:0005838) |
0.1 | 7.0 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.1 | 1.2 | GO:0000242 | pericentriolar material(GO:0000242) |
0.1 | 0.7 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
0.1 | 3.1 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
0.0 | 5.2 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
0.0 | 4.0 | GO:0000118 | histone deacetylase complex(GO:0000118) |
0.0 | 0.4 | GO:0070652 | HAUS complex(GO:0070652) |
0.0 | 3.9 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
0.0 | 2.2 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
0.0 | 0.5 | GO:0032433 | filopodium tip(GO:0032433) |
0.0 | 0.2 | GO:0033391 | chromatoid body(GO:0033391) |
0.0 | 3.7 | GO:0030018 | Z disc(GO:0030018) |
0.0 | 4.2 | GO:0022626 | cytosolic ribosome(GO:0022626) |
0.0 | 0.5 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
0.0 | 0.6 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
0.0 | 16.1 | GO:0005813 | centrosome(GO:0005813) |
0.0 | 1.4 | GO:0005801 | cis-Golgi network(GO:0005801) |
0.0 | 1.9 | GO:0005643 | nuclear pore(GO:0005643) |
0.0 | 0.2 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
0.0 | 27.5 | GO:0005615 | extracellular space(GO:0005615) |
0.0 | 1.4 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
0.0 | 2.8 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
0.0 | 0.2 | GO:0017119 | Golgi transport complex(GO:0017119) |
0.0 | 1.3 | GO:0043292 | contractile fiber(GO:0043292) |
0.0 | 0.8 | GO:0005844 | polysome(GO:0005844) |
0.0 | 0.8 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
0.0 | 0.8 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
0.0 | 0.4 | GO:0035861 | site of double-strand break(GO:0035861) |
0.0 | 0.6 | GO:0031519 | PcG protein complex(GO:0031519) |
0.0 | 1.2 | GO:0016605 | PML body(GO:0016605) |
0.0 | 1.6 | GO:0005923 | bicellular tight junction(GO:0005923) occluding junction(GO:0070160) |
0.0 | 0.5 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.2 | 15.5 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915) |
1.8 | 5.4 | GO:0009881 | photoreceptor activity(GO:0009881) |
1.8 | 5.3 | GO:0035939 | microsatellite binding(GO:0035939) |
1.6 | 9.6 | GO:0004897 | ciliary neurotrophic factor receptor activity(GO:0004897) |
1.5 | 59.9 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
1.5 | 4.4 | GO:0008732 | threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) |
1.3 | 6.3 | GO:0070320 | inward rectifier potassium channel inhibitor activity(GO:0070320) |
1.0 | 3.9 | GO:0031687 | A2A adenosine receptor binding(GO:0031687) |
0.7 | 4.3 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
0.6 | 2.5 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
0.6 | 2.5 | GO:0004999 | vasoactive intestinal polypeptide receptor activity(GO:0004999) |
0.6 | 3.3 | GO:0046404 | ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) |
0.5 | 4.3 | GO:0016308 | 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308) |
0.5 | 2.5 | GO:0001010 | transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) |
0.4 | 2.9 | GO:0016018 | cyclosporin A binding(GO:0016018) |
0.4 | 1.5 | GO:0070976 | calcium-independent protein kinase C activity(GO:0004699) TIR domain binding(GO:0070976) |
0.4 | 1.4 | GO:0046923 | ER retention sequence binding(GO:0046923) |
0.3 | 3.5 | GO:0035197 | siRNA binding(GO:0035197) |
0.3 | 1.9 | GO:0033142 | progesterone receptor binding(GO:0033142) |
0.3 | 3.1 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
0.3 | 1.2 | GO:0033883 | pyridoxal phosphatase activity(GO:0033883) |
0.3 | 1.2 | GO:0017095 | heparan sulfate 6-O-sulfotransferase activity(GO:0017095) |
0.3 | 11.0 | GO:0070412 | R-SMAD binding(GO:0070412) |
0.3 | 2.7 | GO:0004697 | protein kinase C activity(GO:0004697) |
0.3 | 6.3 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
0.2 | 2.2 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
0.2 | 2.1 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
0.2 | 0.7 | GO:0016501 | prostacyclin receptor activity(GO:0016501) |
0.2 | 0.6 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
0.2 | 0.6 | GO:0008534 | oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534) |
0.2 | 2.5 | GO:0031996 | thioesterase binding(GO:0031996) |
0.2 | 0.6 | GO:0008177 | succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538) |
0.2 | 1.4 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
0.2 | 7.4 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
0.2 | 0.7 | GO:0004667 | prostaglandin-D synthase activity(GO:0004667) |
0.2 | 13.9 | GO:0019955 | cytokine binding(GO:0019955) |
0.2 | 5.3 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
0.2 | 1.9 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
0.2 | 1.5 | GO:0031545 | peptidyl-proline 4-dioxygenase activity(GO:0031545) |
0.2 | 1.5 | GO:0030274 | LIM domain binding(GO:0030274) |
0.2 | 2.6 | GO:0017070 | U6 snRNA binding(GO:0017070) |
0.2 | 2.7 | GO:0016857 | racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857) |
0.2 | 1.7 | GO:0032557 | pyrimidine ribonucleotide binding(GO:0032557) |
0.2 | 0.9 | GO:0008494 | translation activator activity(GO:0008494) |
0.1 | 1.5 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
0.1 | 2.4 | GO:0051920 | peroxiredoxin activity(GO:0051920) |
0.1 | 3.3 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
0.1 | 0.8 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
0.1 | 0.5 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
0.1 | 3.2 | GO:0030371 | translation repressor activity(GO:0030371) |
0.1 | 0.6 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
0.1 | 2.5 | GO:0015035 | protein disulfide oxidoreductase activity(GO:0015035) |
0.1 | 0.9 | GO:0001075 | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) |
0.1 | 0.2 | GO:0035851 | Krueppel-associated box domain binding(GO:0035851) |
0.1 | 1.6 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
0.1 | 3.0 | GO:0070840 | dynein complex binding(GO:0070840) |
0.1 | 2.9 | GO:0008009 | chemokine activity(GO:0008009) |
0.1 | 1.8 | GO:0051787 | misfolded protein binding(GO:0051787) |
0.1 | 0.6 | GO:0070411 | I-SMAD binding(GO:0070411) |
0.1 | 2.5 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
0.1 | 1.0 | GO:0003680 | AT DNA binding(GO:0003680) |
0.1 | 7.9 | GO:0033613 | activating transcription factor binding(GO:0033613) |
0.1 | 0.5 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
0.1 | 3.5 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) |
0.1 | 0.9 | GO:0009922 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
0.1 | 0.7 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
0.1 | 1.5 | GO:0000400 | four-way junction DNA binding(GO:0000400) |
0.1 | 6.7 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
0.1 | 2.0 | GO:0030276 | clathrin binding(GO:0030276) |
0.1 | 0.3 | GO:0010484 | H3 histone acetyltransferase activity(GO:0010484) |
0.1 | 4.7 | GO:0019003 | GDP binding(GO:0019003) |
0.1 | 3.1 | GO:0004521 | endoribonuclease activity(GO:0004521) |
0.1 | 0.5 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
0.1 | 2.8 | GO:0005158 | insulin receptor binding(GO:0005158) |
0.1 | 0.5 | GO:0005047 | signal recognition particle binding(GO:0005047) |
0.1 | 12.1 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
0.1 | 0.4 | GO:0004984 | olfactory receptor activity(GO:0004984) |
0.1 | 4.1 | GO:0004519 | endonuclease activity(GO:0004519) |
0.1 | 1.9 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
0.1 | 0.7 | GO:0004576 | oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
0.1 | 1.1 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
0.1 | 1.7 | GO:0005112 | Notch binding(GO:0005112) |
0.0 | 0.6 | GO:0004016 | adenylate cyclase activity(GO:0004016) |
0.0 | 4.0 | GO:0003777 | microtubule motor activity(GO:0003777) |
0.0 | 2.0 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
0.0 | 0.4 | GO:0008227 | G-protein coupled amine receptor activity(GO:0008227) |
0.0 | 1.3 | GO:0008536 | Ran GTPase binding(GO:0008536) |
0.0 | 0.6 | GO:0031702 | type 1 angiotensin receptor binding(GO:0031702) |
0.0 | 0.7 | GO:0017160 | Ral GTPase binding(GO:0017160) |
0.0 | 0.6 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
0.0 | 1.4 | GO:0016811 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811) |
0.0 | 1.0 | GO:0001671 | ATPase activator activity(GO:0001671) |
0.0 | 6.9 | GO:0042393 | histone binding(GO:0042393) |
0.0 | 0.5 | GO:0005521 | lamin binding(GO:0005521) |
0.0 | 1.4 | GO:0036002 | pre-mRNA binding(GO:0036002) |
0.0 | 0.4 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
0.0 | 1.3 | GO:0016763 | transferase activity, transferring pentosyl groups(GO:0016763) carboxy-lyase activity(GO:0016831) |
0.0 | 0.1 | GO:0043682 | copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682) |
0.0 | 3.8 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
0.0 | 0.4 | GO:0031491 | nucleosome binding(GO:0031491) |
0.0 | 0.6 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
0.0 | 1.3 | GO:0008565 | protein transporter activity(GO:0008565) |
0.0 | 0.8 | GO:0015459 | potassium channel regulator activity(GO:0015459) |
0.0 | 0.7 | GO:0004879 | RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531) |
0.0 | 0.3 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
0.0 | 1.5 | GO:0031072 | heat shock protein binding(GO:0031072) |
0.0 | 1.3 | GO:0005506 | iron ion binding(GO:0005506) |
0.0 | 1.9 | GO:0001047 | core promoter binding(GO:0001047) |
0.0 | 0.4 | GO:0008028 | monocarboxylic acid transmembrane transporter activity(GO:0008028) |
0.0 | 0.2 | GO:0003746 | translation elongation factor activity(GO:0003746) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.2 | 63.1 | PID_IGF1_PATHWAY | IGF1 pathway |
0.4 | 10.7 | PID_WNT_CANONICAL_PATHWAY | Canonical Wnt signaling pathway |
0.2 | 7.5 | SA_B_CELL_RECEPTOR_COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
0.2 | 11.2 | PID_BMP_PATHWAY | BMP receptor signaling |
0.2 | 14.5 | PID_LYSOPHOSPHOLIPID_PATHWAY | LPA receptor mediated events |
0.1 | 2.7 | PID_HEDGEHOG_2PATHWAY | Signaling events mediated by the Hedgehog family |
0.1 | 6.8 | PID_HES_HEY_PATHWAY | Notch-mediated HES/HEY network |
0.1 | 11.9 | PID_MYC_ACTIV_PATHWAY | Validated targets of C-MYC transcriptional activation |
0.1 | 1.1 | PID_INSULIN_GLUCOSE_PATHWAY | Insulin-mediated glucose transport |
0.1 | 5.7 | PID_HIF1_TFPATHWAY | HIF-1-alpha transcription factor network |
0.1 | 1.4 | PID_ATF2_PATHWAY | ATF-2 transcription factor network |
0.1 | 2.0 | PID_MAPK_TRK_PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
0.1 | 2.8 | PID_FAK_PATHWAY | Signaling events mediated by focal adhesion kinase |
0.1 | 2.6 | PID_INTEGRIN_A4B1_PATHWAY | Alpha4 beta1 integrin signaling events |
0.1 | 5.4 | PID_CDC42_PATHWAY | CDC42 signaling events |
0.1 | 2.8 | SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES | Genes related to the insulin receptor pathway |
0.1 | 2.2 | PID_DELTA_NP63_PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
0.1 | 1.3 | PID_CD40_PATHWAY | CD40/CD40L signaling |
0.1 | 3.5 | PID_NOTCH_PATHWAY | Notch signaling pathway |
0.1 | 0.7 | PID_PS1_PATHWAY | Presenilin action in Notch and Wnt signaling |
0.1 | 0.6 | PID_BETA_CATENIN_DEG_PATHWAY | Degradation of beta catenin |
0.1 | 3.5 | PID_SMAD2_3NUCLEAR_PATHWAY | Regulation of nuclear SMAD2/3 signaling |
0.1 | 1.4 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
0.1 | 0.6 | PID_INTEGRIN5_PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
0.0 | 2.5 | PID_BETA_CATENIN_NUC_PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
0.0 | 0.8 | PID_IL1_PATHWAY | IL1-mediated signaling events |
0.0 | 0.7 | PID_FOXM1_PATHWAY | FOXM1 transcription factor network |
0.0 | 1.2 | PID_IL12_2PATHWAY | IL12-mediated signaling events |
0.0 | 1.6 | PID_ERA_GENOMIC_PATHWAY | Validated nuclear estrogen receptor alpha network |
0.0 | 4.5 | NABA_SECRETED_FACTORS | Genes encoding secreted soluble factors |
0.0 | 0.6 | PID_HDAC_CLASSI_PATHWAY | Signaling events mediated by HDAC Class I |
0.0 | 1.5 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
0.0 | 1.4 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.8 | 59.6 | REACTOME_SIGNAL_ATTENUATION | Genes involved in Signal attenuation |
0.5 | 8.7 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
0.5 | 5.0 | REACTOME_AMINE_DERIVED_HORMONES | Genes involved in Amine-derived hormones |
0.4 | 13.2 | REACTOME_SIGNALING_BY_BMP | Genes involved in Signaling by BMP |
0.3 | 7.4 | REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
0.3 | 2.5 | REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS | Genes involved in Glucagon-type ligand receptors |
0.3 | 4.2 | REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
0.3 | 2.3 | REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION | Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation |
0.2 | 16.0 | REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
0.2 | 1.8 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
0.2 | 0.2 | REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS | Genes involved in Thrombin signalling through proteinase activated receptors (PARs) |
0.2 | 3.3 | REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
0.2 | 3.3 | REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
0.2 | 1.7 | REACTOME_GLUCURONIDATION | Genes involved in Glucuronidation |
0.2 | 27.4 | REACTOME_G_ALPHA_I_SIGNALLING_EVENTS | Genes involved in G alpha (i) signalling events |
0.2 | 2.9 | REACTOME_P38MAPK_EVENTS | Genes involved in p38MAPK events |
0.2 | 5.2 | REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN | Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein |
0.1 | 1.6 | REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
0.1 | 4.3 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
0.1 | 1.7 | REACTOME_SIGNALING_BY_NOTCH1 | Genes involved in Signaling by NOTCH1 |
0.1 | 1.5 | REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
0.1 | 0.8 | REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING | Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling |
0.1 | 4.3 | REACTOME_GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
0.1 | 3.0 | REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
0.1 | 2.4 | REACTOME_HS_GAG_DEGRADATION | Genes involved in HS-GAG degradation |
0.1 | 1.3 | REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
0.1 | 5.1 | REACTOME_RNA_POL_I_PROMOTER_OPENING | Genes involved in RNA Polymerase I Promoter Opening |
0.1 | 4.5 | REACTOME_MRNA_SPLICING_MINOR_PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
0.1 | 3.4 | REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
0.1 | 1.1 | REACTOME_METABOLISM_OF_NON_CODING_RNA | Genes involved in Metabolism of non-coding RNA |
0.1 | 1.0 | REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
0.1 | 1.0 | REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
0.1 | 1.3 | REACTOME_PYRIMIDINE_METABOLISM | Genes involved in Pyrimidine metabolism |
0.1 | 0.5 | REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
0.1 | 1.7 | REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS | Genes involved in Fatty Acyl-CoA Biosynthesis |
0.1 | 1.5 | REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
0.1 | 1.2 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
0.0 | 0.8 | REACTOME_RNA_POL_III_CHAIN_ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
0.0 | 1.0 | REACTOME_MRNA_3_END_PROCESSING | Genes involved in mRNA 3'-end processing |
0.0 | 2.1 | REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT | Genes involved in Mitochondrial Protein Import |
0.0 | 0.7 | REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
0.0 | 2.3 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
0.0 | 0.3 | REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
0.0 | 0.6 | REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
0.0 | 0.6 | REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
0.0 | 3.4 | REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX | Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex |
0.0 | 1.9 | REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
0.0 | 1.5 | REACTOME_MRNA_SPLICING | Genes involved in mRNA Splicing |
0.0 | 0.6 | REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE | Genes involved in SRP-dependent cotranslational protein targeting to membrane |
0.0 | 5.9 | REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
0.0 | 0.2 | REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
0.0 | 1.4 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
0.0 | 0.5 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |