Motif ID: Pou1f1

Z-value: 0.768


Transcription factors associated with Pou1f1:

Gene SymbolEntrez IDGene Name
Pou1f1 ENSMUSG00000004842.12 Pou1f1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou1f1mm10_v2_chr16_+_65520503_65520548-0.115.1e-01Click!


Activity profile for motif Pou1f1.

activity profile for motif Pou1f1


Sorted Z-values histogram for motif Pou1f1

Sorted Z-values for motif Pou1f1



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou1f1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_26229707 7.727 ENSMUST00000060716.5
ENSMUST00000164660.1
Samd3

sterile alpha motif domain containing 3

chr7_-_103853199 6.159 ENSMUST00000033229.3
Hbb-y
hemoglobin Y, beta-like embryonic chain
chr1_+_107511416 4.361 ENSMUST00000009356.4
Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr1_+_110099295 3.386 ENSMUST00000134301.1
Cdh7
cadherin 7, type 2
chr1_+_107511489 3.183 ENSMUST00000064916.2
Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr9_-_79977782 2.269 ENSMUST00000093811.4
Filip1
filamin A interacting protein 1
chr1_-_75278345 2.182 ENSMUST00000039534.4
Resp18
regulated endocrine-specific protein 18
chr17_+_21690766 2.175 ENSMUST00000097384.1
Gm10509
predicted gene 10509
chr1_+_66364623 1.946 ENSMUST00000077355.5
ENSMUST00000114012.1
Map2

microtubule-associated protein 2

chr1_+_109993982 1.838 ENSMUST00000027542.6
Cdh7
cadherin 7, type 2
chr5_-_53707532 1.821 ENSMUST00000031093.3
Cckar
cholecystokinin A receptor
chr7_-_14562171 1.700 ENSMUST00000181796.1
Vmn1r90
vomeronasal 1 receptor 90
chr7_-_103843154 1.687 ENSMUST00000063957.4
Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr2_+_164074122 1.677 ENSMUST00000018353.7
Stk4
serine/threonine kinase 4
chr7_-_28008416 1.660 ENSMUST00000180024.1
Zfp850
zinc finger protein 850
chr13_-_14523178 1.621 ENSMUST00000110516.2
Hecw1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr10_-_116972609 1.518 ENSMUST00000092165.4
Gm10271
predicted gene 10271
chr6_-_113719880 1.444 ENSMUST00000064993.5
Ghrl
ghrelin
chr14_-_37098211 1.319 ENSMUST00000022337.9
Cdhr1
cadherin-related family member 1
chr1_+_109983737 1.315 ENSMUST00000172005.1
Cdh7
cadherin 7, type 2
chr1_-_79440039 1.220 ENSMUST00000049972.4
Scg2
secretogranin II
chr3_+_125680979 1.212 ENSMUST00000174648.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr13_+_113035111 1.189 ENSMUST00000180543.1
ENSMUST00000181568.1
ENSMUST00000109244.2
ENSMUST00000181117.1
ENSMUST00000181741.1
Cdc20b




cell division cycle 20B




chrX_+_151522352 1.180 ENSMUST00000148622.1
Phf8
PHD finger protein 8
chr6_+_56017489 1.176 ENSMUST00000052827.4
Ppp1r17
protein phosphatase 1, regulatory subunit 17
chr1_+_66386968 1.154 ENSMUST00000145419.1
Map2
microtubule-associated protein 2
chr3_+_146852359 1.118 ENSMUST00000038090.5
ENSMUST00000170055.1
Ttll7

tubulin tyrosine ligase-like family, member 7

chr17_+_21657582 1.106 ENSMUST00000039726.7
3110052M02Rik
RIKEN cDNA 3110052M02 gene
chr1_-_97761538 1.102 ENSMUST00000171129.1
Ppip5k2
diphosphoinositol pentakisphosphate kinase 2
chr17_+_21555046 1.073 ENSMUST00000079242.3
Zfp52
zinc finger protein 52
chr10_-_109009055 0.998 ENSMUST00000156979.1
Syt1
synaptotagmin I
chr9_+_102720287 0.995 ENSMUST00000130602.1
Amotl2
angiomotin-like 2
chr15_-_94404258 0.983 ENSMUST00000035342.4
ENSMUST00000155907.1
Adamts20

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 20

chr4_+_101507947 0.978 ENSMUST00000149047.1
ENSMUST00000106929.3
Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr10_+_37139558 0.972 ENSMUST00000062667.3
5930403N24Rik
RIKEN cDNA 5930403N24 gene
chr11_-_100759942 0.968 ENSMUST00000107363.2
Kcnh4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr5_-_5664196 0.961 ENSMUST00000061008.3
ENSMUST00000054865.6
A330021E22Rik

RIKEN cDNA A330021E22 gene

chr9_-_60687459 0.951 ENSMUST00000114032.1
ENSMUST00000166168.1
ENSMUST00000132366.1
Lrrc49


leucine rich repeat containing 49


chr7_+_139214661 0.937 ENSMUST00000135509.1
Lrrc27
leucine rich repeat containing 27
chr17_+_16972910 0.929 ENSMUST00000071374.5
BC002059
cDNA sequence BC002059
chrX_+_103422010 0.924 ENSMUST00000182089.1
Gm26992
predicted gene, 26992
chr5_+_106609098 0.888 ENSMUST00000167618.1
Gm17304
predicted gene, 17304
chr18_-_62741387 0.887 ENSMUST00000097557.3
Spink13
serine peptidase inhibitor, Kazal type 13
chr1_-_85254548 0.839 ENSMUST00000161685.1
C130026I21Rik
RIKEN cDNA C130026I21 gene
chr14_-_7483762 0.838 ENSMUST00000164366.1
Gm3752
predicted gene 3752
chr8_+_45658273 0.834 ENSMUST00000153798.1
Sorbs2
sorbin and SH3 domain containing 2
chrX_+_42526585 0.830 ENSMUST00000101619.3
Gm10483
predicted gene 10483
chrX_-_75578188 0.828 ENSMUST00000033545.5
Rab39b
RAB39B, member RAS oncogene family
chr2_-_65529275 0.825 ENSMUST00000126837.1
Scn3a
sodium channel, voltage-gated, type III, alpha
chr4_+_86930691 0.824 ENSMUST00000164590.1
Acer2
alkaline ceramidase 2
chr7_-_140082246 0.800 ENSMUST00000166758.2
Caly
calcyon neuron-specific vesicular protein
chr13_-_9878998 0.798 ENSMUST00000063093.9
Chrm3
cholinergic receptor, muscarinic 3, cardiac
chr4_+_43058939 0.797 ENSMUST00000079978.6
Unc13b
unc-13 homolog B (C. elegans)
chr11_-_68927049 0.785 ENSMUST00000038932.7
Odf4
outer dense fiber of sperm tails 4
chr4_+_95579463 0.777 ENSMUST00000150830.1
ENSMUST00000134012.2
Fggy

FGGY carbohydrate kinase domain containing

chr14_-_59395381 0.765 ENSMUST00000166912.2
Phf11c
PHD finger protein 11C
chr4_+_43059028 0.764 ENSMUST00000163653.1
ENSMUST00000107952.2
ENSMUST00000107953.2
Unc13b


unc-13 homolog B (C. elegans)


chr18_+_58659443 0.762 ENSMUST00000025503.8
Isoc1
isochorismatase domain containing 1
chr13_-_58354862 0.745 ENSMUST00000043605.5
Kif27
kinesin family member 27
chr4_+_150855064 0.743 ENSMUST00000030811.1
Errfi1
ERBB receptor feedback inhibitor 1
chr2_+_125866107 0.735 ENSMUST00000134337.1
ENSMUST00000094604.2
ENSMUST00000134798.1
Galk2


galactokinase 2


chr15_+_94629148 0.722 ENSMUST00000080141.4
Tmem117
transmembrane protein 117
chr2_-_181599128 0.712 ENSMUST00000060173.8
Samd10
sterile alpha motif domain containing 10
chr1_-_139377041 0.705 ENSMUST00000059825.5
Crb1
crumbs homolog 1 (Drosophila)
chr1_+_185332143 0.699 ENSMUST00000027916.6
ENSMUST00000151769.1
ENSMUST00000110965.1
Bpnt1


bisphosphate 3'-nucleotidase 1


chrX_+_155262443 0.699 ENSMUST00000026324.9
Acot9
acyl-CoA thioesterase 9
chrX_-_106485214 0.675 ENSMUST00000039447.7
Fndc3c1
fibronectin type III domain containing 3C1
chr18_-_43477764 0.667 ENSMUST00000057110.9
Eif3j2
eukaryotic translation initiation factor 3, subunit J2
chr6_-_42710036 0.661 ENSMUST00000045054.4
Fam115a
family with sequence similarity 115, member A
chr7_+_57590503 0.660 ENSMUST00000085240.4
Gabrb3
gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
chr11_-_11970540 0.658 ENSMUST00000109653.1
Grb10
growth factor receptor bound protein 10
chr16_+_58408443 0.655 ENSMUST00000046663.7
Dcbld2
discoidin, CUB and LCCL domain containing 2
chr10_+_86302854 0.648 ENSMUST00000132307.1
Timp3
tissue inhibitor of metalloproteinase 3
chr8_+_60655540 0.647 ENSMUST00000034066.3
Mfap3l
microfibrillar-associated protein 3-like
chr2_-_24763047 0.644 ENSMUST00000100348.3
ENSMUST00000041342.5
ENSMUST00000114447.1
ENSMUST00000102939.2
ENSMUST00000070864.7
Cacna1b




calcium channel, voltage-dependent, N type, alpha 1B subunit




chr5_-_21785115 0.636 ENSMUST00000115193.1
ENSMUST00000115192.1
ENSMUST00000115195.1
ENSMUST00000030771.5
Dnajc2



DnaJ (Hsp40) homolog, subfamily C, member 2



chrX_-_23266751 0.635 ENSMUST00000115316.2
Klhl13
kelch-like 13
chr13_-_90905321 0.633 ENSMUST00000109541.3
Atp6ap1l
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr8_+_83165348 0.631 ENSMUST00000034145.4
Tbc1d9
TBC1 domain family, member 9
chr6_-_92706145 0.631 ENSMUST00000032093.5
Prickle2
prickle homolog 2 (Drosophila)
chr1_+_72284367 0.623 ENSMUST00000027380.5
ENSMUST00000141783.1
Tmem169

transmembrane protein 169

chr10_-_33624587 0.622 ENSMUST00000160299.1
ENSMUST00000019920.6
Clvs2

clavesin 2

chr1_+_169969409 0.620 ENSMUST00000180638.1
3110045C21Rik
RIKEN cDNA 3110045C21 gene
chr17_-_50094277 0.617 ENSMUST00000113195.1
Rftn1
raftlin lipid raft linker 1
chr17_-_80290476 0.612 ENSMUST00000086555.3
ENSMUST00000038166.7
Dhx57

DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57

chr14_+_4339563 0.612 ENSMUST00000112778.3
2610042L04Rik
RIKEN cDNA 2610042L04 gene
chr11_-_40755201 0.602 ENSMUST00000020576.7
Ccng1
cyclin G1
chr1_-_9748376 0.601 ENSMUST00000057438.6
Vcpip1
valosin containing protein (p97)/p47 complex interacting protein 1
chr6_+_148354648 0.601 ENSMUST00000071745.3
Rps4y2
ribosomal protein S4, Y-linked 2
chr16_+_38346986 0.590 ENSMUST00000050273.8
ENSMUST00000120495.1
ENSMUST00000119704.1
Cox17

Gm21987
cytochrome c oxidase assembly protein 17

predicted gene 21987
chrX_-_7319291 0.588 ENSMUST00000128319.1
Clcn5
chloride channel 5
chr16_+_4968936 0.582 ENSMUST00000090457.5
4930451G09Rik
RIKEN cDNA 4930451G09 gene
chr8_-_9976294 0.581 ENSMUST00000095476.4
Lig4
ligase IV, DNA, ATP-dependent
chrX_+_9885622 0.579 ENSMUST00000067529.2
ENSMUST00000086165.3
Sytl5

synaptotagmin-like 5

chr13_-_21531084 0.576 ENSMUST00000045228.5
Zkscan8
zinc finger with KRAB and SCAN domains 8
chr9_+_104569671 0.570 ENSMUST00000057742.8
Cpne4
copine IV
chr15_-_65014904 0.565 ENSMUST00000110100.2
Gm21961
predicted gene, 21961
chr3_+_76075583 0.561 ENSMUST00000160261.1
Fstl5
follistatin-like 5
chr9_-_107872403 0.561 ENSMUST00000183035.1
Rbm6
RNA binding motif protein 6
chr2_+_104095796 0.559 ENSMUST00000040423.5
ENSMUST00000168176.1
Cd59a

CD59a antigen

chr13_-_91223955 0.554 ENSMUST00000022119.4
Atg10
autophagy related 10
chr2_-_169587745 0.553 ENSMUST00000109160.2
Gm11011
predicted gene 11011
chr18_-_67549173 0.552 ENSMUST00000115050.1
Spire1
spire homolog 1 (Drosophila)
chr19_-_43752924 0.548 ENSMUST00000045562.5
Cox15
cytochrome c oxidase assembly protein 15
chr9_+_88581036 0.548 ENSMUST00000164661.2
Trim43a
tripartite motif-containing 43A
chrX_+_134404780 0.545 ENSMUST00000113224.2
ENSMUST00000113226.1
Drp2

dystrophin related protein 2

chr6_+_149582012 0.536 ENSMUST00000144085.2
Gm21814
predicted gene, 21814
chr4_+_42466752 0.530 ENSMUST00000179734.1
Gm2163
predicted gene 2163
chr14_+_56887795 0.528 ENSMUST00000022511.8
Zmym2
zinc finger, MYM-type 2
chr2_+_49619277 0.527 ENSMUST00000028102.7
Kif5c
kinesin family member 5C
chr18_+_3382979 0.524 ENSMUST00000025073.5
Cul2
cullin 2
chr14_+_105258573 0.520 ENSMUST00000181969.1
Ndfip2
Nedd4 family interacting protein 2
chr2_+_136892168 0.517 ENSMUST00000099311.2
Slx4ip
SLX4 interacting protein
chr7_-_5125937 0.516 ENSMUST00000147835.2
Rasl2-9
RAS-like, family 2, locus 9
chr12_-_20900867 0.515 ENSMUST00000079237.5
Zfp125
zinc finger protein 125
chr13_-_62607499 0.514 ENSMUST00000091563.4
6720489N17Rik
RIKEN cDNA 6720489N17 gene
chr10_+_94550852 0.512 ENSMUST00000148910.1
ENSMUST00000117460.1
Tmcc3

transmembrane and coiled coil domains 3

chrM_+_7759 0.506 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chrX_-_61185558 0.501 ENSMUST00000166381.1
Cdr1
cerebellar degeneration related antigen 1
chr3_+_129532386 0.495 ENSMUST00000071402.2
Elovl6
ELOVL family member 6, elongation of long chain fatty acids (yeast)
chr11_-_103954015 0.493 ENSMUST00000103075.4
Nsf
N-ethylmaleimide sensitive fusion protein
chr18_+_84851338 0.493 ENSMUST00000160180.1
Cyb5
cytochrome b-5
chr7_+_122965636 0.492 ENSMUST00000148880.1
Rbbp6
retinoblastoma binding protein 6
chr3_-_69598822 0.491 ENSMUST00000061826.1
B3galnt1
UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 1
chr3_-_27153861 0.489 ENSMUST00000108300.1
ENSMUST00000108298.2
Ect2

ect2 oncogene

chr10_+_116143881 0.489 ENSMUST00000105271.2
Ptprr
protein tyrosine phosphatase, receptor type, R
chr10_-_67912620 0.487 ENSMUST00000064656.7
Zfp365
zinc finger protein 365
chr16_+_17146937 0.487 ENSMUST00000115706.1
ENSMUST00000069064.4
Ydjc

YdjC homolog (bacterial)

chr3_-_27153782 0.486 ENSMUST00000175857.1
ENSMUST00000177055.1
ENSMUST00000176535.1
Ect2


ect2 oncogene


chr13_-_47043116 0.485 ENSMUST00000110118.1
ENSMUST00000124948.1
ENSMUST00000021806.3
ENSMUST00000136864.1
Tpmt



thiopurine methyltransferase



chr5_-_88527841 0.484 ENSMUST00000087033.3
Igj
immunoglobulin joining chain
chr14_+_105258712 0.484 ENSMUST00000138283.1
Ndfip2
Nedd4 family interacting protein 2
chr16_-_17838173 0.484 ENSMUST00000118960.1
Car15
carbonic anhydrase 15
chr9_+_65890237 0.481 ENSMUST00000045802.6
2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr17_-_28441718 0.481 ENSMUST00000153744.1
Fkbp5
FK506 binding protein 5
chr3_-_105053125 0.480 ENSMUST00000077548.5
Cttnbp2nl
CTTNBP2 N-terminal like
chr3_+_124321031 0.479 ENSMUST00000058994.4
Tram1l1
translocation associated membrane protein 1-like 1
chr6_+_91878034 0.474 ENSMUST00000037783.5
Ccdc174
coiled-coil domain containing 174
chr3_-_92083132 0.471 ENSMUST00000058150.6
Lor
loricrin
chr12_-_81379464 0.466 ENSMUST00000062182.7
Gm4787
predicted gene 4787
chr8_-_54724474 0.464 ENSMUST00000175915.1
Wdr17
WD repeat domain 17
chr9_-_44767792 0.464 ENSMUST00000034607.9
Arcn1
archain 1
chr4_-_36056726 0.460 ENSMUST00000108124.3
Lingo2
leucine rich repeat and Ig domain containing 2
chr7_+_7171330 0.459 ENSMUST00000051435.7
Zfp418
zinc finger protein 418
chr14_+_105258673 0.459 ENSMUST00000136040.2
Ndfip2
Nedd4 family interacting protein 2
chr15_-_98165613 0.458 ENSMUST00000143400.1
Asb8
ankyrin repeat and SOCS box-containing 8
chr2_-_79908389 0.452 ENSMUST00000090756.4
Pde1a
phosphodiesterase 1A, calmodulin-dependent
chr6_-_142387035 0.452 ENSMUST00000032370.6
ENSMUST00000100832.3
ENSMUST00000128082.1
ENSMUST00000111803.2
Recql



RecQ protein-like



chr14_-_57826128 0.452 ENSMUST00000022536.2
Ska3
spindle and kinetochore associated complex subunit 3
chr9_+_67840386 0.452 ENSMUST00000077879.5
Vps13c
vacuolar protein sorting 13C (yeast)
chr6_-_142386974 0.449 ENSMUST00000129694.1
Recql
RecQ protein-like
chrX_-_97377190 0.447 ENSMUST00000037353.3
Eda2r
ectodysplasin A2 receptor
chr2_-_165326435 0.446 ENSMUST00000094329.4
ENSMUST00000074046.6
ENSMUST00000103088.3
ENSMUST00000128690.1
Elmo2



engulfment and cell motility 2



chr17_+_8340710 0.443 ENSMUST00000163887.1
Prr18
proline rich region 18
chr11_+_62574523 0.443 ENSMUST00000018651.7
Trpv2
transient receptor potential cation channel, subfamily V, member 2
chr2_-_65567465 0.441 ENSMUST00000066432.5
Scn3a
sodium channel, voltage-gated, type III, alpha
chr13_+_56522497 0.439 ENSMUST00000045428.6
Fbxl21
F-box and leucine-rich repeat protein 21
chr1_-_16093286 0.438 ENSMUST00000145070.1
ENSMUST00000151004.1
4930444P10Rik

RIKEN cDNA 4930444P10 gene

chr10_-_128180265 0.435 ENSMUST00000099139.1
Rbms2
RNA binding motif, single stranded interacting protein 2
chr1_-_65179058 0.434 ENSMUST00000097709.4
Idh1
isocitrate dehydrogenase 1 (NADP+), soluble
chr4_-_119383732 0.433 ENSMUST00000044781.2
ENSMUST00000084307.3
Ccdc30

coiled-coil domain containing 30

chr9_+_34904913 0.431 ENSMUST00000045091.6
Kirrel3
kin of IRRE like 3 (Drosophila)
chr3_+_94372794 0.431 ENSMUST00000029795.3
Rorc
RAR-related orphan receptor gamma
chrM_+_9452 0.431 ENSMUST00000082411.1
mt-Nd3
mitochondrially encoded NADH dehydrogenase 3
chr9_-_96478660 0.428 ENSMUST00000057500.4
Rnf7
ring finger protein 7
chr1_-_54194048 0.426 ENSMUST00000120904.1
Hecw2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr6_-_115838412 0.425 ENSMUST00000032468.5
ENSMUST00000184428.1
Efcab12

EF-hand calcium binding domain 12

chr2_-_67194695 0.425 ENSMUST00000147939.1
Gm13598
predicted gene 13598
chr13_+_93304940 0.422 ENSMUST00000109497.1
ENSMUST00000109498.1
ENSMUST00000060490.4
ENSMUST00000109492.1
ENSMUST00000109496.1
ENSMUST00000109495.1
Homer1





homer homolog 1 (Drosophila)





chr7_-_118856254 0.419 ENSMUST00000033277.7
Knop1
lysine rich nucleolar protein 1
chr5_+_73006897 0.416 ENSMUST00000031127.7
Slc10a4
solute carrier family 10 (sodium/bile acid cotransporter family), member 4
chr5_-_66514815 0.414 ENSMUST00000161879.1
ENSMUST00000159357.1
Apbb2

amyloid beta (A4) precursor protein-binding, family B, member 2

chr16_+_17489600 0.411 ENSMUST00000115685.1
Aifm3
apoptosis-inducing factor, mitochondrion-associated 3
chr2_-_79908428 0.411 ENSMUST00000102652.3
ENSMUST00000102651.3
Pde1a

phosphodiesterase 1A, calmodulin-dependent

chr13_+_93308006 0.406 ENSMUST00000079086.6
Homer1
homer homolog 1 (Drosophila)
chr5_-_115652974 0.406 ENSMUST00000121746.1
ENSMUST00000118576.1
Ccdc64

coiled-coil domain containing 64

chr2_-_37359274 0.405 ENSMUST00000009174.8
Pdcl
phosducin-like
chr9_-_100506844 0.405 ENSMUST00000112874.3
Nck1
non-catalytic region of tyrosine kinase adaptor protein 1
chr17_+_84511832 0.404 ENSMUST00000047206.5
Plekhh2
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr9_-_78378725 0.400 ENSMUST00000034900.7
Ooep
oocyte expressed protein
chr4_-_42034726 0.396 ENSMUST00000084677.2
Gm21093
predicted gene, 21093
chrX_+_100774741 0.394 ENSMUST00000113735.2
Dlg3
discs, large homolog 3 (Drosophila)
chr1_-_138856819 0.394 ENSMUST00000112025.1
2310009B15Rik
RIKEN cDNA 2310009B15 gene
chr10_+_53337686 0.390 ENSMUST00000046221.6
ENSMUST00000163319.1
Pln

phospholamban

chr13_+_85189433 0.388 ENSMUST00000165077.1
ENSMUST00000164127.1
ENSMUST00000163600.1
Ccnh


cyclin H


chr2_-_59948155 0.387 ENSMUST00000153136.1
Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr3_+_93555080 0.386 ENSMUST00000045756.7
S100a10
S100 calcium binding protein A10 (calpactin)
chr18_-_31911903 0.386 ENSMUST00000054984.6
Sft2d3
SFT2 domain containing 3
chrX_-_157568983 0.384 ENSMUST00000065806.4
Yy2
Yy2 transcription factor
chr4_+_85205120 0.384 ENSMUST00000107188.3
Sh3gl2
SH3-domain GRB2-like 2
chr8_-_83332416 0.383 ENSMUST00000177594.1
ENSMUST00000053902.3
Elmod2

ELMO/CED-12 domain containing 2

chr3_-_53863764 0.381 ENSMUST00000122330.1
ENSMUST00000146598.1
Ufm1

ubiquitin-fold modifier 1

chr12_+_111971545 0.379 ENSMUST00000079009.5
Tdrd9
tudor domain containing 9
chr17_+_32993123 0.379 ENSMUST00000087666.4
ENSMUST00000157017.1
Zfp952

zinc finger protein 952

chr9_-_113708209 0.378 ENSMUST00000111861.3
ENSMUST00000035086.6
Pdcd6ip

programmed cell death 6 interacting protein

chr3_+_103968110 0.377 ENSMUST00000117150.1
ENSMUST00000063717.7
ENSMUST00000055425.8
ENSMUST00000123611.1
ENSMUST00000090685.4
Phtf1




putative homeodomain transcription factor 1




chr2_+_32721055 0.377 ENSMUST00000074248.4
Sh2d3c
SH2 domain containing 3C
chr3_+_96181151 0.375 ENSMUST00000035371.8
Sv2a
synaptic vesicle glycoprotein 2 a
chr11_-_109995775 0.374 ENSMUST00000020948.8
Abca8b
ATP-binding cassette, sub-family A (ABC1), member 8b
chr2_+_136713444 0.370 ENSMUST00000028727.4
ENSMUST00000110098.3
Snap25

synaptosomal-associated protein 25


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 7.8 GO:0015671 oxygen transport(GO:0015671)
0.7 2.2 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.6 1.8 GO:0090274 positive regulation of somatostatin secretion(GO:0090274)
0.5 1.8 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.4 1.7 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.4 1.2 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.3 1.6 GO:0046684 response to pyrethroid(GO:0046684)
0.3 0.9 GO:1902605 heterotrimeric G-protein complex assembly(GO:1902605)
0.3 0.8 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.3 0.8 GO:0033566 gamma-tubulin complex localization(GO:0033566)
0.2 1.2 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.2 0.6 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.2 0.6 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.2 0.6 GO:1904959 regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959)
0.2 0.6 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.2 0.9 GO:0060467 negative regulation of fertilization(GO:0060467)
0.2 1.0 GO:0072318 clathrin coat disassembly(GO:0072318)
0.2 0.6 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.2 0.8 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.2 0.5 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.2 0.6 GO:0060025 regulation of synaptic activity(GO:0060025)
0.2 0.9 GO:0000733 DNA strand renaturation(GO:0000733)
0.1 0.4 GO:0006097 glyoxylate cycle(GO:0006097)
0.1 0.4 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 0.4 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 1.0 GO:0005513 detection of calcium ion(GO:0005513)
0.1 1.1 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.5 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 0.4 GO:0021972 corticospinal neuron axon guidance(GO:0021966) corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.1 1.3 GO:0006020 inositol metabolic process(GO:0006020)
0.1 0.6 GO:0090168 Golgi reassembly(GO:0090168)
0.1 0.7 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.1 0.4 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.1 0.3 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.1 0.2 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.1 0.3 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 0.3 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.1 0.4 GO:0071384 cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385)
0.1 1.0 GO:1902913 positive regulation of melanocyte differentiation(GO:0045636) positive regulation of neuroepithelial cell differentiation(GO:1902913)
0.1 0.6 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.1 0.4 GO:0046874 quinolinate metabolic process(GO:0046874)
0.1 0.7 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 0.3 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.1 0.2 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 1.1 GO:0019321 pentose metabolic process(GO:0019321)
0.1 0.6 GO:0090272 negative regulation of fibroblast growth factor production(GO:0090272)
0.1 0.5 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.1 0.8 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.1 0.4 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 0.3 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.1 0.6 GO:0032596 protein transport into membrane raft(GO:0032596) dsRNA transport(GO:0033227)
0.1 0.4 GO:0032382 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373)
0.1 7.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.3 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.1 3.3 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.1 0.8 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 0.2 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.1 0.7 GO:0071420 cellular response to histamine(GO:0071420)
0.1 0.2 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 0.3 GO:0045113 regulation of integrin biosynthetic process(GO:0045113)
0.1 0.3 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.1 1.0 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.1 0.3 GO:0010920 negative regulation of inositol phosphate biosynthetic process(GO:0010920)
0.1 0.6 GO:0006983 ER overload response(GO:0006983)
0.1 0.2 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.1 0.7 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.1 0.3 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.1 0.3 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 0.4 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.4 GO:0072615 interleukin-17 secretion(GO:0072615)
0.1 0.7 GO:0006012 galactose metabolic process(GO:0006012)
0.1 0.3 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.4 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 0.2 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 0.2 GO:0031392 regulation of prostaglandin biosynthetic process(GO:0031392) regulation of unsaturated fatty acid biosynthetic process(GO:2001279)
0.1 0.5 GO:0031424 keratinization(GO:0031424)
0.1 0.2 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.1 0.5 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.1 0.2 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.1 0.2 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.1 0.6 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.4 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.1 0.2 GO:2000850 protein-chromophore linkage(GO:0018298) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.1 0.7 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.2 GO:2000409 positive regulation of T cell extravasation(GO:2000409)
0.1 0.2 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.4 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.2 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.1 0.3 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.3 GO:0015879 carnitine transport(GO:0015879)
0.0 0.9 GO:0034390 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391) cGMP catabolic process(GO:0046069)
0.0 0.8 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.0 0.4 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.4 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.6 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.5 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 0.9 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0015838 amino-acid betaine transport(GO:0015838)
0.0 0.3 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.3 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.2 GO:0090365 regulation of mRNA modification(GO:0090365)
0.0 0.1 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
0.0 0.1 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.0 0.2 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0 0.3 GO:0034351 negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.2 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.4 GO:0086023 adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.0 0.6 GO:0001956 positive regulation of neurotransmitter secretion(GO:0001956)
0.0 0.2 GO:0072362 regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361) regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.0 2.1 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.0 0.5 GO:0000054 ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753)
0.0 0.3 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.6 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.2 GO:1904659 glucose transmembrane transport(GO:1904659)
0.0 5.0 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.3 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.2 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.0 0.2 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.7 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.7 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.2 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.3 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.3 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.5 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.6 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.1 GO:0044830 activation of signaling protein activity involved in unfolded protein response(GO:0006987) negative regulation by host of viral genome replication(GO:0044828) modulation by host of viral RNA genome replication(GO:0044830)
0.0 0.3 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.0 0.5 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0070859 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.0 0.2 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.1 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.2 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:1990564 protein ufmylation(GO:0071569) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 1.0 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
0.0 0.6 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 0.3 GO:0017144 drug metabolic process(GO:0017144)
0.0 0.3 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.0 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.7 GO:0007094 mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.4 GO:0001765 membrane raft assembly(GO:0001765)
0.0 0.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.4 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.2 GO:0051255 spindle midzone assembly(GO:0051255) mitotic spindle midzone assembly(GO:0051256)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.3 GO:0042711 maternal behavior(GO:0042711)
0.0 0.8 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.4 GO:0030071 regulation of mitotic metaphase/anaphase transition(GO:0030071) regulation of metaphase/anaphase transition of cell cycle(GO:1902099)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.3 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.3 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 1.1 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.3 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.2 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0 0.3 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.1 GO:0034241 positive regulation of macrophage fusion(GO:0034241) regulation of osteoclast proliferation(GO:0090289)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.1 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0 0.5 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.2 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.3 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.0 0.8 GO:0061245 establishment or maintenance of apical/basal cell polarity(GO:0035088) establishment or maintenance of bipolar cell polarity(GO:0061245)
0.0 0.9 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.1 GO:0009414 response to water deprivation(GO:0009414)
0.0 0.2 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.2 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.1 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015) inositol lipid-mediated signaling(GO:0048017)
0.0 0.4 GO:0031297 replication fork processing(GO:0031297)
0.0 0.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.1 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.5 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.3 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.5 GO:0051963 regulation of synapse assembly(GO:0051963) positive regulation of synapse assembly(GO:0051965)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.0 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.3 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.4 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.0 0.1 GO:0090043 tubulin deacetylation(GO:0090042) regulation of tubulin deacetylation(GO:0090043)
0.0 0.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.4 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.1 GO:0045019 negative regulation of nitric oxide biosynthetic process(GO:0045019) negative regulation of nitric oxide metabolic process(GO:1904406)
0.0 0.1 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.1 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.1 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.3 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443) protein K11-linked ubiquitination(GO:0070979)
0.0 0.3 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.3 GO:0021591 ventricular system development(GO:0021591)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 5.8 GO:0005833 hemoglobin complex(GO:0005833)
0.4 2.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.3 3.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.3 0.8 GO:0070985 TFIIK complex(GO:0070985)
0.2 0.7 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.2 1.0 GO:0097149 centralspindlin complex(GO:0097149)
0.1 1.5 GO:0032009 early phagosome(GO:0032009)
0.1 0.5 GO:0030891 VCB complex(GO:0030891)
0.1 1.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 2.0 GO:0031045 dense core granule(GO:0031045)
0.1 1.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.8 GO:0001520 outer dense fiber(GO:0001520)
0.1 0.5 GO:0001533 cornified envelope(GO:0001533)
0.1 0.4 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.1 0.2 GO:1990047 spindle matrix(GO:1990047)
0.1 0.4 GO:0032389 MutLalpha complex(GO:0032389)
0.1 0.3 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.1 0.4 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.1 0.4 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 0.2 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.3 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 0.3 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.1 0.3 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.1 0.2 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 0.2 GO:0044308 axonal spine(GO:0044308)
0.1 0.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.2 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.3 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.3 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.4 GO:0042382 paraspeckles(GO:0042382)
0.0 0.7 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.4 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.3 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.3 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.4 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.6 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.8 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.4 GO:0090543 Flemming body(GO:0090543)
0.0 0.1 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.4 GO:0000796 condensin complex(GO:0000796)
0.0 0.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.4 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.6 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.4 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.3 GO:0032982 myosin filament(GO:0032982)
0.0 0.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.7 GO:0070069 cytochrome complex(GO:0070069)
0.0 0.7 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.5 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.0 1.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 2.3 GO:0043195 terminal bouton(GO:0043195)
0.0 0.3 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.9 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 1.7 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.1 GO:0000922 spindle pole(GO:0000922)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.3 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.3 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.9 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.5 GO:0016592 mediator complex(GO:0016592)
0.0 0.8 GO:0005871 kinesin complex(GO:0005871)
0.0 0.2 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.7 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.3 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.1 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.0 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 7.8 GO:0005344 oxygen transporter activity(GO:0005344)
0.5 1.6 GO:0001565 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
0.4 1.2 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.4 3.1 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.3 1.1 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.3 1.1 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.3 0.8 GO:0071633 dihydroceramidase activity(GO:0071633)
0.2 1.0 GO:0030348 syntaxin-3 binding(GO:0030348)
0.2 0.7 GO:0004335 galactokinase activity(GO:0004335)
0.2 0.7 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.2 0.6 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.2 0.5 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.2 0.7 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.2 1.0 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.2 1.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.2 0.8 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.2 0.9 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 1.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.4 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.1 0.8 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 0.7 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 0.4 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.1 0.9 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 5.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.3 GO:0005124 scavenger receptor binding(GO:0005124)
0.1 1.4 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 0.3 GO:0008527 taste receptor activity(GO:0008527)
0.1 0.7 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.1 0.3 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 0.4 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.6 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.8 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 0.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.3 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.1 0.5 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.4 GO:0050632 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
0.1 0.4 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 0.7 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.3 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 0.6 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.5 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 1.6 GO:0031402 sodium ion binding(GO:0031402)
0.1 0.8 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.1 0.6 GO:0016531 copper chaperone activity(GO:0016531)
0.1 0.6 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.2 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.1 0.4 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.3 GO:0099528 G-protein coupled neurotransmitter receptor activity(GO:0099528)
0.1 0.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.3 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.1 0.3 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.1 0.2 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.1 1.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.2 GO:1990269 RNA polymerase II C-terminal domain phosphoserine binding(GO:1990269)
0.1 0.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.2 GO:0009881 photoreceptor activity(GO:0009881)
0.1 0.4 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 0.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 0.4 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.2 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.4 GO:0048495 GTPase inhibitor activity(GO:0005095) Roundabout binding(GO:0048495)
0.0 0.5 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.3 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.9 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.2 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.3 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 1.5 GO:0050699 WW domain binding(GO:0050699)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.4 GO:1990405 protein antigen binding(GO:1990405)
0.0 0.8 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.2 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.1 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.3 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.4 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.0 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.8 GO:0031489 myosin V binding(GO:0031489)
0.0 0.8 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.2 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 1.6 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.0 0.2 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.8 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.2 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.2 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.3 GO:0035197 siRNA binding(GO:0035197)
0.0 0.2 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.1 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 0.1 GO:0001729 ceramide kinase activity(GO:0001729)
0.0 0.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559) phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0 0.3 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.2 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 0.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.2 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.1 GO:0071568 UFM1 transferase activity(GO:0071568)
0.0 0.2 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.2 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.3 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 2.7 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0036435 deubiquitinase activator activity(GO:0035800) K48-linked polyubiquitin binding(GO:0036435)
0.0 0.1 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.0 GO:0019863 IgE binding(GO:0019863)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.3 GO:0043422 protein kinase B binding(GO:0043422)
0.0 1.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0004697 protein kinase C activity(GO:0004697)
0.0 1.6 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.1 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 6.9 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.3 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.4 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.0 GO:0018738 S-formylglutathione hydrolase activity(GO:0018738)
0.0 0.0 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 ST_INTERLEUKIN_4_PATHWAY Interleukin 4 (IL-4) Pathway
0.0 7.0 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.2 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.3 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 2.9 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.3 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.9 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.4 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.0 0.2 ST_TYPE_I_INTERFERON_PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.3 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 1.0 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.3 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 0.9 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.9 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.4 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.0 PID_PLK1_PATHWAY PLK1 signaling events
0.0 0.3 PID_NFKAPPAB_ATYPICAL_PATHWAY Atypical NF-kappaB pathway
0.0 0.9 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 0.5 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.3 PID_IL23_PATHWAY IL23-mediated signaling events
0.0 0.2 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.0 0.3 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.4 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 0.2 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.1 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 0.1 PID_ALK2_PATHWAY ALK2 signaling events
0.0 0.5 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 0.4 PID_ARF6_PATHWAY Arf6 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.8 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.2 1.6 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.2 1.7 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 0.7 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 0.8 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 2.7 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.1 1.1 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 1.0 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.8 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.0 0.6 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.7 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.0 0.7 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.4 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.9 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.9 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.7 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 1.2 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.4 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 2.4 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.4 REACTOME_REGULATION_OF_IFNA_SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.5 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.5 REACTOME_EARLY_PHASE_OF_HIV_LIFE_CYCLE Genes involved in Early Phase of HIV Life Cycle
0.0 0.3 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.5 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.2 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.0 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.3 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.0 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.2 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.7 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.6 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.2 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.2 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 0.7 REACTOME_PYRUVATE_METABOLISM_AND_CITRIC_ACID_TCA_CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0 1.6 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.4 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.7 REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0 0.2 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.5 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.3 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.0 REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.5 REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.3 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.2 REACTOME_ACTIVATION_OF_CHAPERONES_BY_ATF6_ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 0.4 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.1 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.0 0.2 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.4 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.1 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.0 0.2 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.3 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA