Motif ID: Esr1
Z-value: 0.809

Transcription factors associated with Esr1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Esr1 | ENSMUSG00000019768.10 | Esr1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Esr1 | mm10_v2_chr10_+_4710119_4710166 | 0.30 | 5.5e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.3 | 6.8 | GO:1904274 | tricellular tight junction assembly(GO:1904274) |
0.8 | 2.3 | GO:0060598 | dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598) |
0.7 | 2.8 | GO:0035606 | peptidyl-cysteine S-trans-nitrosylation(GO:0035606) |
0.6 | 1.9 | GO:0015938 | coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) acetyl-CoA catabolic process(GO:0046356) |
0.6 | 2.5 | GO:0002481 | antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481) |
0.6 | 1.8 | GO:0018298 | protein-chromophore linkage(GO:0018298) |
0.6 | 3.0 | GO:0006538 | glutamate catabolic process(GO:0006538) |
0.6 | 1.1 | GO:0046122 | purine deoxyribonucleoside metabolic process(GO:0046122) |
0.5 | 3.2 | GO:0032439 | endosome localization(GO:0032439) |
0.5 | 2.1 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
0.5 | 1.5 | GO:0044413 | regulation of lung blood pressure(GO:0014916) evasion or tolerance of host defenses by virus(GO:0019049) positive regulation of transforming growth factor beta3 production(GO:0032916) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834) |
0.4 | 1.3 | GO:0031204 | posttranslational protein targeting to membrane, translocation(GO:0031204) |
0.4 | 1.3 | GO:0010814 | substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959) |
0.4 | 3.7 | GO:0090267 | positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) |
0.4 | 1.2 | GO:0044778 | meiotic DNA integrity checkpoint(GO:0044778) |
0.4 | 1.2 | GO:0035519 | protein K29-linked ubiquitination(GO:0035519) |
0.4 | 1.6 | GO:0030091 | protein repair(GO:0030091) |
0.4 | 1.2 | GO:0060167 | regulation of adenosine receptor signaling pathway(GO:0060167) regulation of G-protein coupled receptor internalization(GO:1904020) |
0.4 | 1.9 | GO:0019659 | fermentation(GO:0006113) lactate biosynthetic process from pyruvate(GO:0019244) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661) |
0.4 | 1.5 | GO:0010986 | positive regulation of lipoprotein particle clearance(GO:0010986) |
0.4 | 1.1 | GO:0060244 | negative regulation of cell proliferation involved in contact inhibition(GO:0060244) |
0.4 | 1.1 | GO:0010752 | negative regulation of antigen processing and presentation(GO:0002578) negative regulation of nitric oxide mediated signal transduction(GO:0010751) regulation of cGMP-mediated signaling(GO:0010752) |
0.4 | 1.1 | GO:0045819 | plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819) |
0.4 | 2.5 | GO:0010273 | detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169) |
0.3 | 1.6 | GO:0031587 | positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587) positive regulation of neurotrophin production(GO:0032901) |
0.3 | 0.9 | GO:0014738 | regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900) |
0.3 | 1.4 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
0.3 | 1.5 | GO:0043415 | positive regulation of skeletal muscle tissue regeneration(GO:0043415) |
0.3 | 0.8 | GO:0060392 | negative regulation of SMAD protein import into nucleus(GO:0060392) |
0.2 | 0.7 | GO:0009051 | pentose-phosphate shunt, oxidative branch(GO:0009051) |
0.2 | 1.0 | GO:0043973 | histone H3-K4 acetylation(GO:0043973) |
0.2 | 0.7 | GO:1903048 | regulation of acetylcholine-gated cation channel activity(GO:1903048) |
0.2 | 0.7 | GO:0070476 | rRNA (guanine-N7)-methylation(GO:0070476) |
0.2 | 0.7 | GO:0060672 | epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672) |
0.2 | 0.7 | GO:0046061 | dATP catabolic process(GO:0046061) |
0.2 | 0.9 | GO:0002901 | brain renin-angiotensin system(GO:0002035) mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906) positive regulation of arachidonic acid secretion(GO:0090238) |
0.2 | 0.6 | GO:0070093 | negative regulation of glucagon secretion(GO:0070093) |
0.2 | 2.5 | GO:2000254 | regulation of male germ cell proliferation(GO:2000254) |
0.2 | 0.6 | GO:1902498 | regulation of protein autoubiquitination(GO:1902498) |
0.2 | 0.6 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
0.2 | 0.4 | GO:1990869 | response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) |
0.2 | 0.6 | GO:0014063 | negative regulation of serotonin secretion(GO:0014063) |
0.2 | 0.7 | GO:0035021 | negative regulation of Rac protein signal transduction(GO:0035021) |
0.2 | 0.7 | GO:1904565 | response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566) |
0.2 | 3.1 | GO:2000353 | positive regulation of endothelial cell apoptotic process(GO:2000353) |
0.2 | 0.7 | GO:0006751 | glutathione catabolic process(GO:0006751) |
0.2 | 0.2 | GO:0006532 | aspartate biosynthetic process(GO:0006532) |
0.2 | 1.3 | GO:0003056 | regulation of vascular smooth muscle contraction(GO:0003056) |
0.2 | 1.0 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
0.2 | 0.5 | GO:2000510 | regulation of MDA-5 signaling pathway(GO:0039533) positive regulation of dendritic cell chemotaxis(GO:2000510) |
0.2 | 0.5 | GO:0098928 | presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526) |
0.2 | 0.5 | GO:2000312 | regulation of kainate selective glutamate receptor activity(GO:2000312) |
0.2 | 0.6 | GO:1900533 | medium-chain fatty-acyl-CoA catabolic process(GO:0036114) fatty-acyl-CoA catabolic process(GO:0036115) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535) |
0.2 | 0.9 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
0.1 | 1.0 | GO:0000279 | M phase(GO:0000279) |
0.1 | 0.4 | GO:2000393 | negative regulation of lamellipodium morphogenesis(GO:2000393) |
0.1 | 0.4 | GO:0035585 | calcium-mediated signaling using extracellular calcium source(GO:0035585) |
0.1 | 1.4 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
0.1 | 1.0 | GO:0008343 | adult feeding behavior(GO:0008343) |
0.1 | 0.4 | GO:0036166 | phenotypic switching(GO:0036166) |
0.1 | 0.4 | GO:0009174 | UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049) |
0.1 | 0.2 | GO:0002765 | immune response-inhibiting signal transduction(GO:0002765) |
0.1 | 0.4 | GO:0002940 | tRNA N2-guanine methylation(GO:0002940) |
0.1 | 0.5 | GO:0070213 | protein auto-ADP-ribosylation(GO:0070213) |
0.1 | 0.6 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) |
0.1 | 0.3 | GO:0033566 | gamma-tubulin complex localization(GO:0033566) |
0.1 | 0.3 | GO:0072204 | cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) |
0.1 | 0.3 | GO:0010958 | regulation of amino acid import(GO:0010958) |
0.1 | 1.7 | GO:0071459 | protein localization to chromosome, centromeric region(GO:0071459) |
0.1 | 0.3 | GO:0006566 | threonine metabolic process(GO:0006566) |
0.1 | 0.5 | GO:0030423 | targeting of mRNA for destruction involved in RNA interference(GO:0030423) |
0.1 | 0.7 | GO:0019262 | N-acetylneuraminate catabolic process(GO:0019262) |
0.1 | 1.8 | GO:0000920 | cell separation after cytokinesis(GO:0000920) |
0.1 | 0.3 | GO:1903630 | regulation of aminoacyl-tRNA ligase activity(GO:1903630) positive regulation of aminoacyl-tRNA ligase activity(GO:1903632) |
0.1 | 0.4 | GO:0090235 | regulation of metaphase plate congression(GO:0090235) |
0.1 | 0.4 | GO:0021698 | cerebellar cortex structural organization(GO:0021698) |
0.1 | 0.3 | GO:0051030 | snRNA transport(GO:0051030) |
0.1 | 0.4 | GO:0000379 | tRNA-type intron splice site recognition and cleavage(GO:0000379) |
0.1 | 0.6 | GO:2000252 | negative regulation of feeding behavior(GO:2000252) |
0.1 | 1.1 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
0.1 | 0.7 | GO:0009396 | folic acid-containing compound biosynthetic process(GO:0009396) |
0.1 | 0.8 | GO:0006348 | chromatin silencing at telomere(GO:0006348) |
0.1 | 0.6 | GO:1901029 | negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029) |
0.1 | 0.7 | GO:0071865 | regulation of apoptotic process in bone marrow(GO:0071865) negative regulation of apoptotic process in bone marrow(GO:0071866) |
0.1 | 0.8 | GO:0060179 | male mating behavior(GO:0060179) |
0.1 | 0.2 | GO:0002176 | male germ cell proliferation(GO:0002176) |
0.1 | 1.8 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
0.1 | 0.5 | GO:0070127 | tRNA aminoacylation for mitochondrial protein translation(GO:0070127) |
0.1 | 0.6 | GO:0019388 | galactose catabolic process(GO:0019388) |
0.1 | 0.2 | GO:0030300 | regulation of intestinal cholesterol absorption(GO:0030300) |
0.1 | 0.4 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
0.1 | 0.1 | GO:0050859 | negative regulation of B cell receptor signaling pathway(GO:0050859) |
0.1 | 0.3 | GO:1902626 | assembly of large subunit precursor of preribosome(GO:1902626) |
0.1 | 0.4 | GO:0098734 | protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734) |
0.1 | 0.5 | GO:0030579 | ubiquitin-dependent SMAD protein catabolic process(GO:0030579) |
0.1 | 0.3 | GO:0002478 | antigen processing and presentation of exogenous peptide antigen(GO:0002478) |
0.1 | 0.1 | GO:0046121 | deoxyribonucleoside catabolic process(GO:0046121) |
0.1 | 0.6 | GO:0035269 | protein O-linked mannosylation(GO:0035269) |
0.1 | 0.3 | GO:0019276 | UDP-N-acetylgalactosamine metabolic process(GO:0019276) |
0.1 | 0.7 | GO:0019321 | pentose metabolic process(GO:0019321) |
0.1 | 0.2 | GO:0016115 | terpenoid catabolic process(GO:0016115) |
0.1 | 0.3 | GO:0006420 | arginyl-tRNA aminoacylation(GO:0006420) |
0.1 | 0.7 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
0.1 | 0.3 | GO:0006982 | response to lipid hydroperoxide(GO:0006982) cellular response to lipid hydroperoxide(GO:0071449) |
0.1 | 0.2 | GO:0046077 | dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077) |
0.1 | 0.7 | GO:0050849 | negative regulation of calcium-mediated signaling(GO:0050849) |
0.1 | 0.2 | GO:0018343 | protein farnesylation(GO:0018343) |
0.1 | 0.2 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
0.1 | 0.2 | GO:2000304 | positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304) |
0.1 | 1.0 | GO:0071577 | zinc II ion transmembrane transport(GO:0071577) |
0.1 | 0.4 | GO:1905146 | lysosomal protein catabolic process(GO:1905146) |
0.1 | 0.2 | GO:0010510 | regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) |
0.1 | 0.2 | GO:0009597 | detection of virus(GO:0009597) |
0.1 | 0.4 | GO:2000491 | positive regulation of hepatic stellate cell activation(GO:2000491) |
0.1 | 0.9 | GO:0050909 | sensory perception of taste(GO:0050909) |
0.1 | 0.2 | GO:0015786 | UDP-glucose transport(GO:0015786) |
0.1 | 0.4 | GO:0044791 | modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) positive regulation by host of viral genome replication(GO:0044829) |
0.1 | 0.2 | GO:0061744 | motor behavior(GO:0061744) |
0.1 | 0.2 | GO:0006272 | DNA replication, synthesis of RNA primer(GO:0006269) leading strand elongation(GO:0006272) |
0.1 | 0.5 | GO:0008063 | Toll signaling pathway(GO:0008063) |
0.0 | 0.8 | GO:0032464 | positive regulation of protein homooligomerization(GO:0032464) |
0.0 | 0.3 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) |
0.0 | 1.9 | GO:0006418 | tRNA aminoacylation for protein translation(GO:0006418) |
0.0 | 0.0 | GO:0009648 | photoperiodism(GO:0009648) |
0.0 | 0.2 | GO:1902268 | negative regulation of polyamine transmembrane transport(GO:1902268) |
0.0 | 0.2 | GO:2000680 | regulation of rubidium ion transport(GO:2000680) |
0.0 | 0.6 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
0.0 | 0.2 | GO:0075525 | viral translational termination-reinitiation(GO:0075525) |
0.0 | 0.3 | GO:0033563 | dorsal/ventral axon guidance(GO:0033563) |
0.0 | 0.2 | GO:0003376 | sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520) |
0.0 | 0.5 | GO:0061032 | visceral serous pericardium development(GO:0061032) |
0.0 | 0.4 | GO:0001916 | positive regulation of T cell mediated cytotoxicity(GO:0001916) |
0.0 | 0.2 | GO:0000965 | mitochondrial RNA 3'-end processing(GO:0000965) |
0.0 | 0.4 | GO:0006451 | selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451) |
0.0 | 0.6 | GO:0061299 | retina vasculature morphogenesis in camera-type eye(GO:0061299) |
0.0 | 0.2 | GO:0052695 | cellular glucuronidation(GO:0052695) |
0.0 | 0.7 | GO:0043248 | proteasome assembly(GO:0043248) |
0.0 | 0.5 | GO:0070995 | NADPH oxidation(GO:0070995) |
0.0 | 0.5 | GO:0060294 | cilium movement involved in cell motility(GO:0060294) |
0.0 | 0.2 | GO:1904715 | negative regulation of chaperone-mediated autophagy(GO:1904715) |
0.0 | 0.2 | GO:0051126 | negative regulation of actin nucleation(GO:0051126) |
0.0 | 0.5 | GO:0034219 | carbohydrate transmembrane transport(GO:0034219) |
0.0 | 0.2 | GO:0071294 | cellular response to zinc ion(GO:0071294) |
0.0 | 0.3 | GO:0006627 | protein processing involved in protein targeting to mitochondrion(GO:0006627) |
0.0 | 0.2 | GO:0072086 | specification of loop of Henle identity(GO:0072086) |
0.0 | 0.1 | GO:0016132 | brassinosteroid metabolic process(GO:0016131) brassinosteroid biosynthetic process(GO:0016132) |
0.0 | 0.3 | GO:0061002 | negative regulation of dendritic spine morphogenesis(GO:0061002) |
0.0 | 0.3 | GO:0035845 | photoreceptor cell outer segment organization(GO:0035845) |
0.0 | 0.3 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
0.0 | 1.1 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
0.0 | 0.3 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
0.0 | 0.9 | GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I(GO:0002474) |
0.0 | 1.7 | GO:0051290 | protein heterotetramerization(GO:0051290) |
0.0 | 0.6 | GO:0006516 | glycoprotein catabolic process(GO:0006516) |
0.0 | 0.1 | GO:0090204 | protein localization to nuclear pore(GO:0090204) positive regulation of calcium-transporting ATPase activity(GO:1901896) |
0.0 | 0.2 | GO:0018401 | peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) |
0.0 | 1.0 | GO:0006783 | heme biosynthetic process(GO:0006783) |
0.0 | 0.4 | GO:0014823 | response to activity(GO:0014823) |
0.0 | 0.1 | GO:0036066 | protein O-linked fucosylation(GO:0036066) |
0.0 | 0.1 | GO:0046022 | regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022) |
0.0 | 0.9 | GO:0033962 | cytoplasmic mRNA processing body assembly(GO:0033962) |
0.0 | 0.3 | GO:0060539 | diaphragm development(GO:0060539) |
0.0 | 0.1 | GO:0033092 | positive regulation of immature T cell proliferation in thymus(GO:0033092) positive regulation of interleukin-6 biosynthetic process(GO:0045410) |
0.0 | 0.5 | GO:0006825 | copper ion transport(GO:0006825) |
0.0 | 0.4 | GO:0043923 | positive regulation by host of viral transcription(GO:0043923) |
0.0 | 0.1 | GO:1901052 | sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053) |
0.0 | 0.8 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.0 | 0.6 | GO:0008340 | determination of adult lifespan(GO:0008340) |
0.0 | 0.3 | GO:0021891 | olfactory bulb interneuron development(GO:0021891) |
0.0 | 0.1 | GO:0043328 | protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) |
0.0 | 0.1 | GO:0006742 | NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364) |
0.0 | 0.8 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
0.0 | 0.1 | GO:0097026 | myeloid dendritic cell chemotaxis(GO:0002408) dendritic cell dendrite assembly(GO:0097026) mature conventional dendritic cell differentiation(GO:0097029) |
0.0 | 0.1 | GO:0044375 | regulation of peroxisome size(GO:0044375) |
0.0 | 0.6 | GO:0070527 | platelet aggregation(GO:0070527) |
0.0 | 0.2 | GO:0098789 | pre-mRNA cleavage required for polyadenylation(GO:0098789) |
0.0 | 0.1 | GO:2000620 | positive regulation of histone H4-K16 acetylation(GO:2000620) |
0.0 | 0.2 | GO:0006388 | tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388) |
0.0 | 1.0 | GO:0097031 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
0.0 | 0.5 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
0.0 | 0.7 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
0.0 | 0.3 | GO:0051292 | nuclear pore complex assembly(GO:0051292) |
0.0 | 0.3 | GO:0045292 | mRNA cis splicing, via spliceosome(GO:0045292) |
0.0 | 0.3 | GO:0033211 | adiponectin-activated signaling pathway(GO:0033211) |
0.0 | 0.1 | GO:0080184 | response to stilbenoid(GO:0035634) response to phenylpropanoid(GO:0080184) |
0.0 | 0.2 | GO:0043589 | skin morphogenesis(GO:0043589) |
0.0 | 0.2 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
0.0 | 0.2 | GO:0031118 | rRNA pseudouridine synthesis(GO:0031118) |
0.0 | 0.5 | GO:0048025 | negative regulation of mRNA splicing, via spliceosome(GO:0048025) |
0.0 | 0.5 | GO:0009649 | entrainment of circadian clock(GO:0009649) |
0.0 | 0.6 | GO:0045494 | photoreceptor cell maintenance(GO:0045494) |
0.0 | 0.1 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
0.0 | 0.0 | GO:0009838 | abscission(GO:0009838) |
0.0 | 0.1 | GO:0090666 | scaRNA localization to Cajal body(GO:0090666) |
0.0 | 0.3 | GO:0031648 | protein destabilization(GO:0031648) |
0.0 | 0.3 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
0.0 | 0.4 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
0.0 | 0.2 | GO:0033623 | regulation of integrin activation(GO:0033623) |
0.0 | 1.0 | GO:0071479 | cellular response to ionizing radiation(GO:0071479) |
0.0 | 0.1 | GO:0051534 | negative regulation of NFAT protein import into nucleus(GO:0051534) |
0.0 | 1.1 | GO:0097194 | execution phase of apoptosis(GO:0097194) |
0.0 | 0.1 | GO:0071340 | skeletal muscle acetylcholine-gated channel clustering(GO:0071340) |
0.0 | 0.2 | GO:0050774 | negative regulation of dendrite morphogenesis(GO:0050774) |
0.0 | 0.1 | GO:0035878 | nail development(GO:0035878) |
0.0 | 1.2 | GO:0007338 | single fertilization(GO:0007338) |
0.0 | 0.1 | GO:0018002 | N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920) |
0.0 | 0.2 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
0.0 | 0.2 | GO:0035024 | negative regulation of Rho protein signal transduction(GO:0035024) |
0.0 | 0.1 | GO:0042559 | pteridine-containing compound biosynthetic process(GO:0042559) |
0.0 | 0.1 | GO:0018242 | protein O-linked glycosylation via serine(GO:0018242) |
0.0 | 0.3 | GO:0071260 | cellular response to mechanical stimulus(GO:0071260) |
0.0 | 0.1 | GO:0021559 | trigeminal nerve development(GO:0021559) |
0.0 | 0.0 | GO:0051892 | negative regulation of cardioblast differentiation(GO:0051892) |
0.0 | 0.3 | GO:0014002 | astrocyte development(GO:0014002) |
0.0 | 0.2 | GO:0006857 | oligopeptide transport(GO:0006857) |
0.0 | 0.4 | GO:0048011 | neurotrophin TRK receptor signaling pathway(GO:0048011) |
0.0 | 0.4 | GO:0002377 | immunoglobulin production(GO:0002377) |
0.0 | 0.2 | GO:0033008 | positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306) |
0.0 | 0.5 | GO:0006284 | base-excision repair(GO:0006284) |
0.0 | 0.2 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
0.0 | 0.1 | GO:0060340 | positive regulation of type I interferon-mediated signaling pathway(GO:0060340) |
0.0 | 0.1 | GO:0006474 | N-terminal protein amino acid acetylation(GO:0006474) |
0.0 | 0.4 | GO:0051651 | maintenance of location in cell(GO:0051651) |
0.0 | 0.1 | GO:0097067 | cellular response to thyroid hormone stimulus(GO:0097067) |
0.0 | 0.2 | GO:0051123 | RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.1 | 6.8 | GO:0061689 | tricellular tight junction(GO:0061689) |
0.5 | 3.2 | GO:0045179 | apical cortex(GO:0045179) |
0.5 | 3.5 | GO:0097452 | GAIT complex(GO:0097452) |
0.5 | 2.4 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
0.4 | 1.3 | GO:0031205 | endoplasmic reticulum Sec complex(GO:0031205) |
0.4 | 1.1 | GO:0005577 | fibrinogen complex(GO:0005577) |
0.3 | 1.7 | GO:0033093 | Weibel-Palade body(GO:0033093) |
0.3 | 2.7 | GO:0061574 | ASAP complex(GO:0061574) |
0.3 | 1.5 | GO:0071144 | SMAD2-SMAD3 protein complex(GO:0071144) |
0.3 | 1.2 | GO:0000939 | condensed chromosome inner kinetochore(GO:0000939) |
0.3 | 1.0 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
0.2 | 2.7 | GO:0042612 | MHC class I protein complex(GO:0042612) |
0.2 | 3.0 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
0.2 | 1.2 | GO:0030896 | checkpoint clamp complex(GO:0030896) |
0.2 | 0.6 | GO:0005588 | collagen type V trimer(GO:0005588) |
0.2 | 0.5 | GO:0042720 | mitochondrial inner membrane peptidase complex(GO:0042720) |
0.2 | 1.5 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
0.2 | 0.6 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
0.1 | 1.0 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
0.1 | 0.9 | GO:0000214 | tRNA-intron endonuclease complex(GO:0000214) |
0.1 | 0.4 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
0.1 | 0.7 | GO:0031012 | extracellular matrix(GO:0031012) |
0.1 | 0.7 | GO:0033061 | DNA recombinase mediator complex(GO:0033061) |
0.1 | 0.8 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
0.1 | 0.3 | GO:1990730 | VCP-NSFL1C complex(GO:1990730) |
0.1 | 0.6 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
0.1 | 0.5 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
0.1 | 0.7 | GO:0042611 | MHC protein complex(GO:0042611) |
0.1 | 0.2 | GO:0005584 | collagen type I trimer(GO:0005584) |
0.1 | 0.2 | GO:0034666 | integrin alpha2-beta1 complex(GO:0034666) |
0.1 | 0.8 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
0.1 | 0.3 | GO:0071006 | U2-type catalytic step 1 spliceosome(GO:0071006) |
0.1 | 0.5 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
0.1 | 0.4 | GO:0030120 | vesicle coat(GO:0030120) |
0.1 | 0.4 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
0.1 | 0.3 | GO:1902636 | kinociliary basal body(GO:1902636) |
0.1 | 0.3 | GO:1903349 | omegasome membrane(GO:1903349) |
0.1 | 0.7 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
0.1 | 0.4 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
0.1 | 0.2 | GO:0034457 | Mpp10 complex(GO:0034457) |
0.1 | 0.4 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
0.1 | 0.7 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
0.1 | 0.2 | GO:0071920 | cleavage body(GO:0071920) |
0.1 | 2.3 | GO:0060077 | inhibitory synapse(GO:0060077) |
0.1 | 0.5 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
0.1 | 0.2 | GO:0032585 | multivesicular body membrane(GO:0032585) |
0.1 | 0.8 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
0.1 | 0.5 | GO:0089701 | U2AF(GO:0089701) |
0.1 | 3.6 | GO:0005581 | collagen trimer(GO:0005581) |
0.1 | 4.5 | GO:0005643 | nuclear pore(GO:0005643) |
0.0 | 0.1 | GO:0031417 | NatC complex(GO:0031417) |
0.0 | 0.6 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
0.0 | 0.2 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
0.0 | 0.3 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
0.0 | 0.7 | GO:0031083 | BLOC-1 complex(GO:0031083) |
0.0 | 0.3 | GO:0005956 | protein kinase CK2 complex(GO:0005956) |
0.0 | 2.3 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
0.0 | 0.6 | GO:1990023 | mitotic spindle midzone(GO:1990023) |
0.0 | 1.0 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
0.0 | 0.6 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
0.0 | 0.2 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
0.0 | 0.3 | GO:0005638 | lamin filament(GO:0005638) |
0.0 | 0.4 | GO:0044754 | autolysosome(GO:0044754) |
0.0 | 0.5 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
0.0 | 0.1 | GO:0000814 | ESCRT II complex(GO:0000814) |
0.0 | 0.2 | GO:0005850 | eukaryotic translation initiation factor 2 complex(GO:0005850) |
0.0 | 2.1 | GO:0005871 | kinesin complex(GO:0005871) |
0.0 | 0.5 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
0.0 | 0.2 | GO:0070876 | SOSS complex(GO:0070876) |
0.0 | 0.4 | GO:0031931 | TORC1 complex(GO:0031931) |
0.0 | 0.5 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
0.0 | 0.4 | GO:0030061 | mitochondrial crista(GO:0030061) |
0.0 | 0.2 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
0.0 | 0.1 | GO:0031510 | SUMO activating enzyme complex(GO:0031510) |
0.0 | 0.2 | GO:0045261 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261) |
0.0 | 1.0 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
0.0 | 1.6 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
0.0 | 0.9 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
0.0 | 0.4 | GO:0005614 | interstitial matrix(GO:0005614) |
0.0 | 0.3 | GO:0000796 | condensin complex(GO:0000796) |
0.0 | 0.3 | GO:0071011 | precatalytic spliceosome(GO:0071011) |
0.0 | 1.2 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
0.0 | 0.3 | GO:0097228 | sperm principal piece(GO:0097228) |
0.0 | 0.7 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
0.0 | 0.3 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
0.0 | 0.1 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
0.0 | 0.2 | GO:0032426 | stereocilium tip(GO:0032426) |
0.0 | 1.7 | GO:0001669 | acrosomal vesicle(GO:0001669) |
0.0 | 0.3 | GO:0005839 | proteasome core complex(GO:0005839) |
0.0 | 0.6 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
0.0 | 0.3 | GO:0032433 | filopodium tip(GO:0032433) |
0.0 | 0.4 | GO:0005669 | transcription factor TFIID complex(GO:0005669) |
0.0 | 0.1 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
0.0 | 1.6 | GO:0005814 | centriole(GO:0005814) |
0.0 | 0.8 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
0.0 | 0.7 | GO:0005719 | nuclear euchromatin(GO:0005719) |
0.0 | 0.1 | GO:0000313 | organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761) |
0.0 | 0.3 | GO:0034451 | centriolar satellite(GO:0034451) |
0.0 | 0.2 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
0.0 | 1.4 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
0.0 | 0.2 | GO:0031597 | cytosolic proteasome complex(GO:0031597) |
0.0 | 0.2 | GO:0002178 | palmitoyltransferase complex(GO:0002178) |
0.0 | 0.2 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
0.0 | 1.0 | GO:0000794 | condensed nuclear chromosome(GO:0000794) |
0.0 | 2.4 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
0.0 | 0.1 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
0.0 | 0.2 | GO:0097546 | ciliary base(GO:0097546) |
0.0 | 0.2 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
0.0 | 0.1 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
0.0 | 0.0 | GO:0045251 | mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251) |
0.0 | 0.0 | GO:0097543 | ciliary inversin compartment(GO:0097543) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 2.8 | GO:0035605 | peptidyl-cysteine S-nitrosylase activity(GO:0035605) |
0.6 | 1.9 | GO:0003986 | acetyl-CoA hydrolase activity(GO:0003986) |
0.6 | 1.8 | GO:0009881 | photoreceptor activity(GO:0009881) |
0.5 | 1.9 | GO:0004459 | L-lactate dehydrogenase activity(GO:0004459) |
0.4 | 2.1 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
0.4 | 7.1 | GO:0030169 | low-density lipoprotein particle binding(GO:0030169) |
0.4 | 2.8 | GO:0004351 | glutamate decarboxylase activity(GO:0004351) |
0.4 | 1.1 | GO:0004731 | purine-nucleoside phosphorylase activity(GO:0004731) |
0.4 | 1.5 | GO:0008970 | phosphatidylcholine 1-acylhydrolase activity(GO:0008970) |
0.4 | 1.1 | GO:0000402 | open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402) |
0.4 | 2.1 | GO:0043199 | Ran guanyl-nucleotide exchange factor activity(GO:0005087) sulfate binding(GO:0043199) |
0.3 | 1.0 | GO:0030629 | U6 snRNA 3'-end binding(GO:0030629) |
0.3 | 1.5 | GO:0030618 | transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) |
0.3 | 1.2 | GO:0031687 | A2A adenosine receptor binding(GO:0031687) |
0.3 | 1.6 | GO:0033743 | peptide-methionine (R)-S-oxide reductase activity(GO:0033743) |
0.2 | 0.7 | GO:0017057 | 6-phosphogluconolactonase activity(GO:0017057) |
0.2 | 1.4 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
0.2 | 0.9 | GO:0004111 | creatine kinase activity(GO:0004111) |
0.2 | 0.7 | GO:0036470 | tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478) |
0.2 | 0.6 | GO:0031779 | melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782) |
0.2 | 1.6 | GO:0048403 | brain-derived neurotrophic factor binding(GO:0048403) |
0.2 | 1.3 | GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450) |
0.2 | 1.0 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
0.2 | 1.5 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
0.2 | 0.8 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
0.2 | 0.6 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
0.1 | 0.4 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
0.1 | 0.6 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
0.1 | 0.7 | GO:0001010 | transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) |
0.1 | 1.1 | GO:0048495 | Roundabout binding(GO:0048495) |
0.1 | 0.5 | GO:0004667 | prostaglandin-D synthase activity(GO:0004667) |
0.1 | 0.7 | GO:0008494 | translation activator activity(GO:0008494) |
0.1 | 0.5 | GO:0030984 | kininogen binding(GO:0030984) |
0.1 | 1.6 | GO:0002161 | aminoacyl-tRNA editing activity(GO:0002161) |
0.1 | 1.0 | GO:0030274 | LIM domain binding(GO:0030274) |
0.1 | 0.5 | GO:0004809 | tRNA (guanine-N2-)-methyltransferase activity(GO:0004809) |
0.1 | 0.7 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915) |
0.1 | 0.3 | GO:0008732 | threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) |
0.1 | 0.3 | GO:0004980 | melanocortin receptor activity(GO:0004977) melanocyte-stimulating hormone receptor activity(GO:0004980) |
0.1 | 0.5 | GO:0032767 | copper-dependent protein binding(GO:0032767) |
0.1 | 0.7 | GO:0008242 | omega peptidase activity(GO:0008242) |
0.1 | 0.6 | GO:0051429 | corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
0.1 | 0.6 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
0.1 | 0.9 | GO:0046977 | TAP binding(GO:0046977) |
0.1 | 0.5 | GO:0046404 | ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) |
0.1 | 0.7 | GO:0047429 | nucleoside-triphosphate diphosphatase activity(GO:0047429) |
0.1 | 0.2 | GO:0005128 | erythropoietin receptor binding(GO:0005128) |
0.1 | 0.6 | GO:0031419 | cobalamin binding(GO:0031419) |
0.1 | 2.2 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
0.1 | 0.2 | GO:0046624 | sphingolipid transporter activity(GO:0046624) |
0.1 | 0.4 | GO:0023029 | MHC class Ib protein binding(GO:0023029) |
0.1 | 1.1 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
0.1 | 0.9 | GO:0016863 | intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863) |
0.1 | 0.6 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
0.1 | 0.7 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
0.1 | 0.7 | GO:0003857 | 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857) |
0.1 | 0.6 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
0.1 | 0.5 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
0.1 | 0.3 | GO:0047237 | glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237) glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238) |
0.1 | 0.3 | GO:0004814 | arginine-tRNA ligase activity(GO:0004814) arginine binding(GO:0034618) |
0.1 | 0.9 | GO:0070742 | C2H2 zinc finger domain binding(GO:0070742) |
0.1 | 0.5 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
0.1 | 0.2 | GO:0030519 | snoRNP binding(GO:0030519) |
0.1 | 0.3 | GO:0005459 | UDP-galactose transmembrane transporter activity(GO:0005459) |
0.1 | 0.3 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
0.1 | 0.4 | GO:0000213 | tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892) |
0.1 | 0.2 | GO:0009041 | uridylate kinase activity(GO:0009041) |
0.1 | 0.2 | GO:0033677 | DNA/RNA helicase activity(GO:0033677) |
0.1 | 1.7 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
0.1 | 1.0 | GO:0051400 | BH domain binding(GO:0051400) |
0.1 | 0.5 | GO:0016618 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
0.1 | 0.8 | GO:0017070 | U6 snRNA binding(GO:0017070) |
0.1 | 0.3 | GO:0010858 | calcium-dependent protein kinase regulator activity(GO:0010858) |
0.1 | 0.2 | GO:0004699 | calcium-independent protein kinase C activity(GO:0004699) |
0.1 | 0.6 | GO:0036042 | long-chain fatty acyl-CoA binding(GO:0036042) |
0.1 | 0.8 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
0.1 | 0.2 | GO:0004069 | L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) |
0.1 | 0.2 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
0.1 | 0.2 | GO:0030171 | voltage-gated proton channel activity(GO:0030171) |
0.1 | 0.8 | GO:0005542 | folic acid binding(GO:0005542) |
0.1 | 0.7 | GO:0042605 | peptide antigen binding(GO:0042605) |
0.0 | 0.3 | GO:0043176 | amine binding(GO:0043176) |
0.0 | 0.8 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
0.0 | 1.1 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
0.0 | 0.2 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
0.0 | 0.8 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
0.0 | 2.2 | GO:0035255 | ionotropic glutamate receptor binding(GO:0035255) |
0.0 | 0.6 | GO:0001530 | lipopolysaccharide binding(GO:0001530) |
0.0 | 0.3 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
0.0 | 0.6 | GO:0005537 | mannose binding(GO:0005537) |
0.0 | 0.4 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
0.0 | 0.3 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
0.0 | 0.2 | GO:0035614 | snRNA stem-loop binding(GO:0035614) |
0.0 | 0.7 | GO:0016857 | racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857) |
0.0 | 0.4 | GO:0019865 | immunoglobulin binding(GO:0019865) |
0.0 | 0.4 | GO:0008301 | DNA binding, bending(GO:0008301) |
0.0 | 1.8 | GO:0005507 | copper ion binding(GO:0005507) |
0.0 | 0.2 | GO:0004311 | farnesyltranstransferase activity(GO:0004311) |
0.0 | 1.0 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.0 | 0.8 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
0.0 | 1.1 | GO:0005227 | calcium activated cation channel activity(GO:0005227) |
0.0 | 0.1 | GO:0072541 | peroxynitrite reductase activity(GO:0072541) |
0.0 | 0.2 | GO:0016453 | acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453) |
0.0 | 0.3 | GO:0015197 | peptide transporter activity(GO:0015197) |
0.0 | 0.3 | GO:0008484 | sulfuric ester hydrolase activity(GO:0008484) |
0.0 | 0.1 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
0.0 | 0.1 | GO:0009918 | sterol delta7 reductase activity(GO:0009918) 7-dehydrocholesterol reductase activity(GO:0047598) |
0.0 | 0.5 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
0.0 | 0.4 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
0.0 | 0.1 | GO:0002054 | nucleobase binding(GO:0002054) |
0.0 | 0.1 | GO:0004155 | 6,7-dihydropteridine reductase activity(GO:0004155) |
0.0 | 0.6 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
0.0 | 0.2 | GO:0019841 | retinol binding(GO:0019841) |
0.0 | 0.4 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
0.0 | 2.3 | GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980) |
0.0 | 1.1 | GO:0050699 | WW domain binding(GO:0050699) |
0.0 | 0.3 | GO:0008430 | selenium binding(GO:0008430) |
0.0 | 0.5 | GO:0010485 | H4 histone acetyltransferase activity(GO:0010485) |
0.0 | 0.3 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
0.0 | 1.3 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
0.0 | 0.2 | GO:0031545 | peptidyl-proline 4-dioxygenase activity(GO:0031545) |
0.0 | 0.2 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
0.0 | 0.1 | GO:0003692 | left-handed Z-DNA binding(GO:0003692) |
0.0 | 0.3 | GO:0015643 | toxic substance binding(GO:0015643) |
0.0 | 1.1 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.0 | 2.1 | GO:0003777 | microtubule motor activity(GO:0003777) |
0.0 | 0.3 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
0.0 | 0.3 | GO:0035497 | cAMP response element binding(GO:0035497) |
0.0 | 0.8 | GO:0016876 | aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876) |
0.0 | 0.1 | GO:0032564 | dATP binding(GO:0032564) |
0.0 | 0.2 | GO:0015347 | sodium-independent organic anion transmembrane transporter activity(GO:0015347) |
0.0 | 0.1 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
0.0 | 3.8 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
0.0 | 0.2 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
0.0 | 0.7 | GO:0019200 | carbohydrate kinase activity(GO:0019200) |
0.0 | 0.4 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
0.0 | 0.5 | GO:0001158 | enhancer sequence-specific DNA binding(GO:0001158) |
0.0 | 0.2 | GO:0031005 | filamin binding(GO:0031005) |
0.0 | 0.1 | GO:0031735 | CCR10 chemokine receptor binding(GO:0031735) |
0.0 | 0.2 | GO:0003746 | translation elongation factor activity(GO:0003746) |
0.0 | 0.2 | GO:0019103 | pyrimidine nucleotide binding(GO:0019103) |
0.0 | 0.9 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
0.0 | 0.2 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
0.0 | 0.2 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
0.0 | 0.2 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
0.0 | 0.3 | GO:0017049 | GTP-Rho binding(GO:0017049) |
0.0 | 0.7 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
0.0 | 0.1 | GO:0008556 | sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556) |
0.0 | 0.4 | GO:0030506 | ankyrin binding(GO:0030506) |
0.0 | 0.4 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.0 | 0.0 | GO:0036132 | 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522) |
0.0 | 0.1 | GO:0004679 | AMP-activated protein kinase activity(GO:0004679) |
0.0 | 0.3 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
0.0 | 0.3 | GO:0017147 | Wnt-protein binding(GO:0017147) |
0.0 | 0.6 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.0 | 2.8 | GO:0008022 | protein C-terminus binding(GO:0008022) |
0.0 | 0.2 | GO:0048020 | CCR chemokine receptor binding(GO:0048020) |
0.0 | 0.9 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 4.4 | NABA_COLLAGENS | Genes encoding collagen proteins |
0.1 | 9.2 | PID_MYC_ACTIV_PATHWAY | Validated targets of C-MYC transcriptional activation |
0.1 | 2.7 | PID_FOXM1_PATHWAY | FOXM1 transcription factor network |
0.1 | 1.8 | PID_DELTA_NP63_PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
0.0 | 2.0 | PID_AURORA_B_PATHWAY | Aurora B signaling |
0.0 | 2.2 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
0.0 | 1.9 | PID_IL12_2PATHWAY | IL12-mediated signaling events |
0.0 | 1.1 | PID_AMB2_NEUTROPHILS_PATHWAY | amb2 Integrin signaling |
0.0 | 2.4 | PID_HEDGEHOG_GLI_PATHWAY | Hedgehog signaling events mediated by Gli proteins |
0.0 | 1.4 | PID_ALPHA_SYNUCLEIN_PATHWAY | Alpha-synuclein signaling |
0.0 | 0.6 | PID_CIRCADIAN_PATHWAY | Circadian rhythm pathway |
0.0 | 1.3 | PID_FANCONI_PATHWAY | Fanconi anemia pathway |
0.0 | 0.9 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
0.0 | 0.2 | PID_TRAIL_PATHWAY | TRAIL signaling pathway |
0.0 | 0.3 | PID_NFKAPPAB_ATYPICAL_PATHWAY | Atypical NF-kappaB pathway |
0.0 | 0.3 | PID_SYNDECAN_3_PATHWAY | Syndecan-3-mediated signaling events |
0.0 | 3.1 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
0.0 | 0.5 | PID_IL4_2PATHWAY | IL4-mediated signaling events |
0.0 | 0.4 | PID_LYMPH_ANGIOGENESIS_PATHWAY | VEGFR3 signaling in lymphatic endothelium |
0.0 | 0.3 | PID_PRL_SIGNALING_EVENTS_PATHWAY | Signaling events mediated by PRL |
0.0 | 0.5 | PID_ATM_PATHWAY | ATM pathway |
0.0 | 0.7 | PID_INTEGRIN1_PATHWAY | Beta1 integrin cell surface interactions |
0.0 | 0.5 | PID_EPO_PATHWAY | EPO signaling pathway |
0.0 | 0.4 | PID_AURORA_A_PATHWAY | Aurora A signaling |
0.0 | 0.9 | PID_HIF1_TFPATHWAY | HIF-1-alpha transcription factor network |
0.0 | 1.8 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
0.0 | 0.3 | PID_EPHA_FWDPATHWAY | EPHA forward signaling |
0.0 | 0.1 | PID_TCR_JNK_PATHWAY | JNK signaling in the CD4+ TCR pathway |
0.0 | 0.7 | PID_RAC1_PATHWAY | RAC1 signaling pathway |
0.0 | 0.5 | PID_P53_REGULATION_PATHWAY | p53 pathway |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 4.7 | REACTOME_INHIBITION_OF_THE_PROTEOLYTIC_ACTIVITY_OF_APC_C_REQUIRED_FOR_THE_ONSET_OF_ANAPHASE_BY_MITOTIC_SPINDLE_CHECKPOINT_COMPONENTS | Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components |
0.2 | 0.7 | REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
0.1 | 3.0 | REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
0.1 | 5.4 | REACTOME_GLYCOLYSIS | Genes involved in Glycolysis |
0.1 | 1.1 | REACTOME_PURINE_CATABOLISM | Genes involved in Purine catabolism |
0.1 | 1.1 | REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
0.1 | 2.2 | REACTOME_PYRUVATE_METABOLISM | Genes involved in Pyruvate metabolism |
0.1 | 0.9 | REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
0.1 | 0.7 | REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
0.1 | 0.9 | REACTOME_INTRINSIC_PATHWAY | Genes involved in Intrinsic Pathway |
0.1 | 1.9 | REACTOME_SIGNALING_BY_NODAL | Genes involved in Signaling by NODAL |
0.1 | 1.9 | REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
0.1 | 1.0 | REACTOME_RAF_MAP_KINASE_CASCADE | Genes involved in RAF/MAP kinase cascade |
0.1 | 1.7 | REACTOME_KINESINS | Genes involved in Kinesins |
0.1 | 1.0 | REACTOME_ZINC_TRANSPORTERS | Genes involved in Zinc transporters |
0.1 | 0.9 | REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
0.1 | 0.5 | REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
0.1 | 1.3 | REACTOME_FANCONI_ANEMIA_PATHWAY | Genes involved in Fanconi Anemia pathway |
0.0 | 2.9 | REACTOME_ER_PHAGOSOME_PATHWAY | Genes involved in ER-Phagosome pathway |
0.0 | 0.5 | REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND | Genes involved in Removal of the Flap Intermediate from the C-strand |
0.0 | 0.8 | REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
0.0 | 0.2 | REACTOME_PROCESSIVE_SYNTHESIS_ON_THE_LAGGING_STRAND | Genes involved in Processive synthesis on the lagging strand |
0.0 | 0.7 | REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
0.0 | 0.6 | REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
0.0 | 2.5 | REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS | Genes involved in Regulation of Water Balance by Renal Aquaporins |
0.0 | 0.8 | REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
0.0 | 3.2 | REACTOME_MITOTIC_PROMETAPHASE | Genes involved in Mitotic Prometaphase |
0.0 | 0.4 | REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
0.0 | 0.3 | REACTOME_P2Y_RECEPTORS | Genes involved in P2Y receptors |
0.0 | 1.6 | REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
0.0 | 0.2 | REACTOME_TRANSPORT_OF_ORGANIC_ANIONS | Genes involved in Transport of organic anions |
0.0 | 0.9 | REACTOME_RNA_POL_I_TRANSCRIPTION_INITIATION | Genes involved in RNA Polymerase I Transcription Initiation |
0.0 | 1.4 | REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT | Genes involved in Mitochondrial Protein Import |
0.0 | 0.2 | REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
0.0 | 0.5 | REACTOME_PYRIMIDINE_METABOLISM | Genes involved in Pyrimidine metabolism |
0.0 | 1.9 | REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS | Genes involved in Host Interactions of HIV factors |
0.0 | 0.4 | REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
0.0 | 0.1 | REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI | Genes involved in RIP-mediated NFkB activation via DAI |
0.0 | 0.5 | REACTOME_GLUTATHIONE_CONJUGATION | Genes involved in Glutathione conjugation |
0.0 | 0.3 | REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
0.0 | 0.4 | REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
0.0 | 0.2 | REACTOME_PROLACTIN_RECEPTOR_SIGNALING | Genes involved in Prolactin receptor signaling |
0.0 | 1.1 | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT | Genes involved in Respiratory electron transport |
0.0 | 0.4 | REACTOME_ERK_MAPK_TARGETS | Genes involved in ERK/MAPK targets |
0.0 | 0.7 | REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
0.0 | 1.3 | REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE | Genes involved in SRP-dependent cotranslational protein targeting to membrane |
0.0 | 0.3 | REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
0.0 | 0.2 | REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY | Genes involved in TRAF3-dependent IRF activation pathway |
0.0 | 0.5 | REACTOME_MRNA_3_END_PROCESSING | Genes involved in mRNA 3'-end processing |
0.0 | 0.2 | REACTOME_METABOLISM_OF_POLYAMINES | Genes involved in Metabolism of polyamines |
0.0 | 0.3 | REACTOME_METABOLISM_OF_PORPHYRINS | Genes involved in Metabolism of porphyrins |
0.0 | 0.1 | REACTOME_COPI_MEDIATED_TRANSPORT | Genes involved in COPI Mediated Transport |
0.0 | 0.1 | REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION | Genes involved in Antigen processing-Cross presentation |