Motif ID: E2f8

Z-value: 1.875


Transcription factors associated with E2f8:

Gene SymbolEntrez IDGene Name
E2f8 ENSMUSG00000046179.11 E2f8

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
E2f8mm10_v2_chr7_-_48881596_488816190.951.3e-20Click!


Activity profile for motif E2f8.

activity profile for motif E2f8


Sorted Z-values histogram for motif E2f8

Sorted Z-values for motif E2f8



Network of associatons between targets according to the STRING database.



First level regulatory network of E2f8

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_89302545 22.034 ENSMUST00000061728.3
Nog
noggin
chr8_+_75109528 16.064 ENSMUST00000164309.1
Mcm5
minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)
chr17_+_56040350 12.445 ENSMUST00000002914.8
Chaf1a
chromatin assembly factor 1, subunit A (p150)
chr17_+_56303321 12.025 ENSMUST00000001258.8
Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
chr11_+_26387194 11.016 ENSMUST00000109509.1
ENSMUST00000136830.1
Fancl

Fanconi anemia, complementation group L

chr9_-_36726374 10.210 ENSMUST00000172702.2
ENSMUST00000172742.1
ENSMUST00000034625.5
Chek1


checkpoint kinase 1


chr17_+_56303396 10.162 ENSMUST00000113038.1
Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
chr2_-_34913976 10.101 ENSMUST00000028232.3
Phf19
PHD finger protein 19
chr16_-_46496955 9.911 ENSMUST00000023335.6
ENSMUST00000023334.8
Pvrl3

poliovirus receptor-related 3

chr16_-_46496772 9.803 ENSMUST00000149901.1
ENSMUST00000096052.2
Pvrl3

poliovirus receptor-related 3

chr12_+_24708984 9.620 ENSMUST00000154588.1
Rrm2
ribonucleotide reductase M2
chr1_-_128359610 9.308 ENSMUST00000027601.4
Mcm6
minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)
chr11_+_98907801 9.250 ENSMUST00000092706.6
Cdc6
cell division cycle 6
chr7_-_48881032 9.101 ENSMUST00000058745.8
E2f8
E2F transcription factor 8
chr6_-_94700137 9.086 ENSMUST00000101126.2
ENSMUST00000032105.4
Lrig1

leucine-rich repeats and immunoglobulin-like domains 1

chr7_-_27337667 8.686 ENSMUST00000038618.6
ENSMUST00000108369.2
Ltbp4

latent transforming growth factor beta binding protein 4

chr16_-_18811615 8.309 ENSMUST00000096990.3
Cdc45
cell division cycle 45
chr7_-_48881596 8.193 ENSMUST00000119223.1
E2f8
E2F transcription factor 8
chr7_-_115824699 8.169 ENSMUST00000169129.1
Sox6
SRY-box containing gene 6
chr6_-_88898664 7.963 ENSMUST00000058011.6
Mcm2
minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
chr10_-_21160925 7.874 ENSMUST00000020158.6
Myb
myeloblastosis oncogene
chr12_+_24708241 7.577 ENSMUST00000020980.5
Rrm2
ribonucleotide reductase M2
chr4_+_132768325 7.575 ENSMUST00000102561.4
Rpa2
replication protein A2
chr2_+_163054682 7.494 ENSMUST00000018005.3
Mybl2
myeloblastosis oncogene-like 2
chr5_+_123749696 7.199 ENSMUST00000031366.7
Kntc1
kinetochore associated 1
chr10_+_128015157 6.999 ENSMUST00000178041.1
ENSMUST00000026461.7
Prim1

DNA primase, p49 subunit

chr11_-_101785252 6.799 ENSMUST00000164750.1
ENSMUST00000107176.1
ENSMUST00000017868.6
Etv4


ets variant gene 4 (E1A enhancer binding protein, E1AF)


chr8_+_40926220 6.686 ENSMUST00000034004.9
Pdgfrl
platelet-derived growth factor receptor-like
chr7_-_44548733 6.625 ENSMUST00000145956.1
ENSMUST00000049343.8
Pold1

polymerase (DNA directed), delta 1, catalytic subunit

chr13_+_19623163 6.565 ENSMUST00000002883.5
Sfrp4
secreted frizzled-related protein 4
chr5_+_111581422 6.396 ENSMUST00000064930.3
C130026L21Rik
RIKEN cDNA C130026L21 gene
chr19_+_38931008 6.343 ENSMUST00000145051.1
Hells
helicase, lymphoid specific
chr16_-_15637277 6.124 ENSMUST00000023353.3
Mcm4
minichromosome maintenance deficient 4 homolog (S. cerevisiae)
chr19_+_38930909 5.790 ENSMUST00000025965.5
Hells
helicase, lymphoid specific
chr15_+_78926720 5.529 ENSMUST00000089377.5
Lgals1
lectin, galactose binding, soluble 1
chr6_+_117917281 5.506 ENSMUST00000180020.1
ENSMUST00000177570.1
Hnrnpf

heterogeneous nuclear ribonucleoprotein F

chr5_-_33652296 5.444 ENSMUST00000151081.1
ENSMUST00000101354.3
Slbp

stem-loop binding protein

chr2_+_23321246 5.323 ENSMUST00000102945.1
Nxph2
neurexophilin 2
chr6_+_117916981 5.178 ENSMUST00000179478.1
Hnrnpf
heterogeneous nuclear ribonucleoprotein F
chr2_-_157204483 5.107 ENSMUST00000029170.7
Rbl1
retinoblastoma-like 1 (p107)
chr7_+_110122299 5.103 ENSMUST00000033326.8
Wee1
WEE 1 homolog 1 (S. pombe)
chr16_+_10835046 4.664 ENSMUST00000037913.8
Rmi2
RMI2, RecQ mediated genome instability 2, homolog (S. cerevisiae)
chr2_+_145785980 4.232 ENSMUST00000110005.1
ENSMUST00000094480.4
Rin2

Ras and Rab interactor 2

chr5_-_65335597 3.980 ENSMUST00000172660.1
ENSMUST00000172732.1
ENSMUST00000031092.8
Rfc1


replication factor C (activator 1) 1


chr9_+_103305156 3.827 ENSMUST00000035164.3
Topbp1
topoisomerase (DNA) II binding protein 1
chr5_-_65335564 3.645 ENSMUST00000172780.1
Rfc1
replication factor C (activator 1) 1
chr1_+_131910458 3.558 ENSMUST00000062264.6
Nucks1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr5_+_129020069 3.529 ENSMUST00000031383.7
ENSMUST00000111343.1
Ran

RAN, member RAS oncogene family

chr4_-_129189646 3.281 ENSMUST00000106059.1
S100pbp
S100P binding protein
chr5_-_33652339 3.169 ENSMUST00000075670.6
Slbp
stem-loop binding protein
chr2_-_84743655 3.057 ENSMUST00000181711.1
Gm19426
predicted gene, 19426
chr4_-_129189512 3.057 ENSMUST00000117965.1
ENSMUST00000106061.2
ENSMUST00000072431.6
S100pbp


S100P binding protein


chr16_-_18248697 2.815 ENSMUST00000115645.3
Ranbp1
RAN binding protein 1
chr4_-_129189600 2.793 ENSMUST00000117497.1
ENSMUST00000117350.1
S100pbp

S100P binding protein

chr12_+_110279228 2.608 ENSMUST00000097228.4
Dio3
deiodinase, iodothyronine type III
chr7_+_102065713 2.082 ENSMUST00000094129.2
ENSMUST00000094130.2
ENSMUST00000084843.3
Trpc2


transient receptor potential cation channel, subfamily C, member 2


chr2_-_154569720 1.991 ENSMUST00000000894.5
E2f1
E2F transcription factor 1
chr2_-_154569845 1.959 ENSMUST00000103145.4
E2f1
E2F transcription factor 1
chr10_+_42860348 1.911 ENSMUST00000063063.7
Scml4
sex comb on midleg-like 4 (Drosophila)
chr5_+_150673739 1.841 ENSMUST00000016569.4
ENSMUST00000038900.8
Pds5b

PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)

chr9_-_35116804 1.835 ENSMUST00000034537.6
St3gal4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr5_+_137787769 1.791 ENSMUST00000035852.7
Zcwpw1
zinc finger, CW type with PWWP domain 1
chr18_-_9726670 1.602 ENSMUST00000171339.1
Gm17430
predicted gene, 17430
chr15_+_55557399 1.581 ENSMUST00000022998.7
Mtbp
Mdm2, transformed 3T3 cell double minute p53 binding protein
chr7_+_102065485 1.389 ENSMUST00000106950.1
ENSMUST00000146450.1
Trpc2

transient receptor potential cation channel, subfamily C, member 2

chr11_-_21572193 1.134 ENSMUST00000102874.4
Mdh1
malate dehydrogenase 1, NAD (soluble)
chr17_+_33909577 1.083 ENSMUST00000170075.2
Daxx
Fas death domain-associated protein
chr17_+_33909481 1.045 ENSMUST00000173626.1
ENSMUST00000174541.1
Daxx

Fas death domain-associated protein

chr3_-_127553233 1.033 ENSMUST00000029588.5
Larp7
La ribonucleoprotein domain family, member 7
chrX_-_73716145 0.999 ENSMUST00000002091.5
Bcap31
B cell receptor associated protein 31
chr1_-_168431695 0.985 ENSMUST00000176790.1
Pbx1
pre B cell leukemia homeobox 1
chr11_+_88047693 0.744 ENSMUST00000079866.4
Srsf1
serine/arginine-rich splicing factor 1
chr6_-_87851011 0.707 ENSMUST00000113617.1
Cnbp
cellular nucleic acid binding protein
chr17_-_35235755 0.644 ENSMUST00000048994.6
Nfkbil1
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor like 1
chr9_+_22003035 0.369 ENSMUST00000115331.2
ENSMUST00000003493.7
Prkcsh

protein kinase C substrate 80K-H

chr15_+_55557575 0.356 ENSMUST00000170046.1
Mtbp
Mdm2, transformed 3T3 cell double minute p53 binding protein
chr11_+_21572221 0.305 ENSMUST00000020568.3
ENSMUST00000131135.1
Wdpcp

WD repeat containing planar cell polarity effector

chr9_+_61372359 0.218 ENSMUST00000178113.1
ENSMUST00000159386.1
Tle3

transducin-like enhancer of split 3, homolog of Drosophila E(spl)

chr11_+_77462325 0.206 ENSMUST00000102493.1
Coro6
coronin 6
chr6_+_35177386 0.188 ENSMUST00000043815.9
Nup205
nucleoporin 205
chr1_-_168431896 0.079 ENSMUST00000176540.1
Pbx1
pre B cell leukemia homeobox 1
chr10_+_116301374 0.046 ENSMUST00000092167.5
Ptprb
protein tyrosine phosphatase, receptor type, B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.8 17.3 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
5.5 22.0 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
3.0 9.1 GO:0032474 otolith morphogenesis(GO:0032474)
2.8 8.3 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) DNA replication preinitiation complex assembly(GO:0071163) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
2.3 23.4 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
2.3 34.3 GO:0010216 maintenance of DNA methylation(GO:0010216)
2.2 6.6 GO:0045004 DNA replication proofreading(GO:0045004)
2.2 6.6 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
1.7 7.0 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
1.4 10.1 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
1.3 4.0 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
1.3 13.0 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
1.2 3.6 GO:0019046 release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382)
1.1 6.8 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
1.1 29.1 GO:0006270 DNA replication initiation(GO:0006270)
1.1 8.6 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
1.0 17.2 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.9 5.5 GO:0002317 plasma cell differentiation(GO:0002317) positive regulation of viral entry into host cell(GO:0046598)
0.7 8.2 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.7 3.5 GO:0002121 inter-male aggressive behavior(GO:0002121) response to pheromone(GO:0019236)
0.5 7.9 GO:0051571 positive regulation of histone H3-K4 methylation(GO:0051571)
0.5 2.0 GO:0072737 response to diamide(GO:0072737) cellular response to diamide(GO:0072738)
0.5 1.8 GO:0007064 sister chromatid cohesion(GO:0007062) mitotic sister chromatid cohesion(GO:0007064)
0.4 3.5 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.4 12.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.4 1.6 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.4 1.9 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.4 2.6 GO:0046549 phenol-containing compound catabolic process(GO:0019336) retinal cone cell development(GO:0046549)
0.3 7.6 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.3 1.0 GO:1904154 protein localization to endoplasmic reticulum exit site(GO:0070973) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.2 1.1 GO:0006108 malate metabolic process(GO:0006108)
0.1 7.5 GO:0090307 mitotic spindle assembly(GO:0090307)
0.1 5.1 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.1 1.0 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.1 0.6 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1 4.7 GO:0033045 regulation of sister chromatid segregation(GO:0033045)
0.1 0.3 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.1 4.4 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.0 1.1 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0 8.7 GO:0007179 transforming growth factor beta receptor signaling pathway(GO:0007179)
0.0 1.8 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 5.1 GO:0030010 establishment of cell polarity(GO:0030010)
0.0 0.4 GO:0006491 N-glycan processing(GO:0006491)
0.0 10.4 GO:0007276 gamete generation(GO:0007276)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 12.4 GO:0033186 CAF-1 complex(GO:0033186)
3.4 17.2 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
2.8 8.3 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
2.5 37.7 GO:0042555 MCM complex(GO:0042555)
2.4 7.2 GO:1990423 RZZ complex(GO:1990423)
2.2 6.6 GO:0043625 delta DNA polymerase complex(GO:0043625)
1.5 7.5 GO:0031523 Myb complex(GO:0031523)
1.4 7.0 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
1.3 7.6 GO:0005663 DNA replication factor C complex(GO:0005663)
1.2 8.6 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
1.2 3.5 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
1.0 11.0 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.8 4.0 GO:0035189 Rb-E2F complex(GO:0035189)
0.6 39.4 GO:0005657 replication fork(GO:0005657)
0.4 12.1 GO:0005721 pericentric heterochromatin(GO:0005721)
0.3 3.8 GO:0001673 male germ cell nucleus(GO:0001673)
0.3 6.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 7.1 GO:0051233 spindle midzone(GO:0051233)
0.2 1.0 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.2 2.8 GO:1904115 axon cytoplasm(GO:1904115)
0.1 2.0 GO:0001741 XY body(GO:0001741)
0.1 3.5 GO:0032590 dendrite membrane(GO:0032590)
0.1 7.4 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 28.9 GO:0005667 transcription factor complex(GO:0005667)
0.1 1.9 GO:0000776 kinetochore(GO:0000776)
0.0 14.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 18.8 GO:0030424 axon(GO:0030424)
0.0 6.8 GO:0016607 nuclear speck(GO:0016607)
0.0 1.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.3 GO:0044447 axoneme part(GO:0044447)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
5.5 22.2 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
3.4 17.2 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
3.4 10.2 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
2.9 8.6 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
2.3 32.3 GO:0003688 DNA replication origin binding(GO:0003688)
2.0 7.9 GO:0071987 WD40-repeat domain binding(GO:0071987)
1.6 12.4 GO:0070087 chromo shadow domain binding(GO:0070087)
1.2 7.5 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
1.1 5.5 GO:0005534 galactose binding(GO:0005534)
0.7 6.6 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.7 7.6 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.6 3.5 GO:0070883 pre-miRNA binding(GO:0070883)
0.6 7.6 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.5 1.8 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.4 15.4 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.4 8.7 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.4 21.0 GO:0019955 cytokine binding(GO:0019955)
0.3 3.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.3 6.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.3 10.7 GO:0017025 TBP-class protein binding(GO:0017025)
0.2 1.1 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.2 7.0 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.2 5.0 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 25.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 2.8 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 8.5 GO:0035064 methylated histone binding(GO:0035064)
0.1 9.1 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 12.1 GO:0004386 helicase activity(GO:0004386)
0.1 2.0 GO:0008432 JUN kinase binding(GO:0008432)
0.1 4.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 1.0 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 4.3 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 11.0 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 4.0 GO:0001047 core promoter binding(GO:0001047)
0.0 3.6 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 15.3 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.6 28.6 PID_ATR_PATHWAY ATR signaling pathway
0.5 19.7 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.4 11.0 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.4 33.3 PID_E2F_PATHWAY E2F transcription factor network
0.4 18.5 PID_BMP_PATHWAY BMP receptor signaling
0.3 12.1 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 3.5 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.2 9.1 PID_ERBB4_PATHWAY ErbB4 signaling events
0.2 14.0 PID_CMYB_PATHWAY C-MYB transcription factor network
0.2 7.6 PID_FAS_PATHWAY FAS (CD95) signaling pathway
0.1 5.5 PID_RAS_PATHWAY Regulation of Ras family activation
0.1 2.0 PID_HIV_NEF_PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1 4.2 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 6.6 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.1 8.7 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.6 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.0 1.1 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 47.8 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
1.7 15.3 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
1.7 30.4 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
1.6 21.2 REACTOME_PROCESSIVE_SYNTHESIS_ON_THE_LAGGING_STRAND Genes involved in Processive synthesis on the lagging strand
0.7 22.0 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.7 8.6 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.7 11.8 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.6 19.7 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.5 11.0 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.2 2.6 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.2 3.5 REACTOME_MICRORNA_MIRNA_BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 7.9 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 9.1 REACTOME_SIGNALING_BY_EGFR_IN_CANCER Genes involved in Signaling by EGFR in Cancer
0.0 0.4 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 3.7 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.0 1.1 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 2.5 REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE Genes involved in Late Phase of HIV Life Cycle
0.0 1.0 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins