Motif ID: Zic3

Z-value: 0.888


Transcription factors associated with Zic3:

Gene SymbolEntrez IDGene Name
Zic3 ENSMUSG00000067860.5 Zic3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zic3mm10_v2_chrX_+_58030999_580310180.542.5e-04Click!


Activity profile for motif Zic3.

activity profile for motif Zic3


Sorted Z-values histogram for motif Zic3

Sorted Z-values for motif Zic3



Network of associatons between targets according to the STRING database.



First level regulatory network of Zic3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_53159885 2.987 ENSMUST00000030010.3
Abca1
ATP-binding cassette, sub-family A (ABC1), member 1
chr2_+_120629113 2.097 ENSMUST00000150912.1
ENSMUST00000180041.1
Stard9

START domain containing 9

chr2_-_39190687 2.080 ENSMUST00000142872.1
ENSMUST00000038874.5
Scai

suppressor of cancer cell invasion

chr13_+_44729535 1.898 ENSMUST00000174068.1
Jarid2
jumonji, AT rich interactive domain 2
chr2_-_160872985 1.831 ENSMUST00000109460.1
ENSMUST00000127201.1
Zhx3

zinc fingers and homeoboxes 3

chr2_-_146511899 1.731 ENSMUST00000131824.1
Ralgapa2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr5_-_114273702 1.712 ENSMUST00000144050.1
ENSMUST00000044790.5
Foxn4

forkhead box N4

chr2_-_180776900 1.630 ENSMUST00000108878.1
Bhlhe23
basic helix-loop-helix family, member e23
chr10_+_18845071 1.563 ENSMUST00000019998.7
Perp
PERP, TP53 apoptosis effector
chr7_+_127800604 1.493 ENSMUST00000046863.5
ENSMUST00000106272.1
ENSMUST00000139068.1
Hsd3b7


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7


chr13_+_44730726 1.451 ENSMUST00000173704.1
ENSMUST00000044608.7
ENSMUST00000173367.1
Jarid2


jumonji, AT rich interactive domain 2


chr12_-_76709997 1.431 ENSMUST00000166101.1
Sptb
spectrin beta, erythrocytic
chrX_+_56454871 1.402 ENSMUST00000039374.2
ENSMUST00000101553.2
Ddx26b

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

chr10_+_106470281 1.368 ENSMUST00000029404.9
ENSMUST00000169303.1
Ppfia2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr1_-_64121389 1.364 ENSMUST00000055001.3
Klf7
Kruppel-like factor 7 (ubiquitous)
chr2_-_160872829 1.348 ENSMUST00000176141.1
Zhx3
zinc fingers and homeoboxes 3
chr5_+_137288273 1.324 ENSMUST00000024099.4
ENSMUST00000085934.3
Ache

acetylcholinesterase

chr4_+_108165449 1.289 ENSMUST00000116309.3
ENSMUST00000116307.1
Echdc2

enoyl Coenzyme A hydratase domain containing 2

chr4_+_108165432 1.225 ENSMUST00000052999.6
Echdc2
enoyl Coenzyme A hydratase domain containing 2
chr9_+_59750876 1.151 ENSMUST00000136740.1
ENSMUST00000135298.1
ENSMUST00000128341.1
Myo9a


myosin IXa


chr9_-_56418023 1.147 ENSMUST00000061552.8
C230081A13Rik
RIKEN cDNA C230081A13 gene
chr9_-_123678873 1.131 ENSMUST00000040960.6
Slc6a20a
solute carrier family 6 (neurotransmitter transporter), member 20A
chr11_-_118248489 1.127 ENSMUST00000100181.4
Cyth1
cytohesin 1
chr9_-_123678782 1.117 ENSMUST00000170591.1
ENSMUST00000171647.1
Slc6a20a

solute carrier family 6 (neurotransmitter transporter), member 20A

chr11_+_3332426 1.113 ENSMUST00000136474.1
Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr2_-_160872552 1.111 ENSMUST00000103111.2
Zhx3
zinc fingers and homeoboxes 3
chr1_-_64121456 1.098 ENSMUST00000142009.1
ENSMUST00000114086.1
Klf7

Kruppel-like factor 7 (ubiquitous)

chr2_+_127008711 1.079 ENSMUST00000110394.1
ENSMUST00000002063.8
Ap4e1

adaptor-related protein complex AP-4, epsilon 1

chrX_+_37126777 1.078 ENSMUST00000016553.4
Nkap
NFKB activating protein
chr6_-_56362356 1.046 ENSMUST00000044505.7
ENSMUST00000166102.1
ENSMUST00000164037.1
ENSMUST00000114327.2
Pde1c



phosphodiesterase 1C



chr11_-_98149551 1.042 ENSMUST00000103143.3
Fbxl20
F-box and leucine-rich repeat protein 20
chr6_+_48395652 1.039 ENSMUST00000077093.4
Krba1
KRAB-A domain containing 1
chr10_+_28074813 1.035 ENSMUST00000166468.1
Ptprk
protein tyrosine phosphatase, receptor type, K
chr12_+_112620030 1.028 ENSMUST00000180015.1
ENSMUST00000021726.6
Adssl1

adenylosuccinate synthetase like 1

chr3_-_102204576 1.025 ENSMUST00000159388.1
Vangl1
vang-like 1 (van gogh, Drosophila)
chr4_-_62208426 1.010 ENSMUST00000068822.3
Zfp37
zinc finger protein 37
chr1_-_58586191 0.996 ENSMUST00000038372.7
ENSMUST00000097724.3
ENSMUST00000161000.1
ENSMUST00000161600.1
Fam126b



family with sequence similarity 126, member B



chr12_-_27342696 0.995 ENSMUST00000079063.5
Sox11
SRY-box containing gene 11
chr1_+_179668202 0.978 ENSMUST00000040538.3
Sccpdh
saccharopine dehydrogenase (putative)
chr11_+_79339792 0.968 ENSMUST00000108251.2
ENSMUST00000071325.2
Nf1

neurofibromatosis 1

chr16_-_91044473 0.930 ENSMUST00000118522.1
Paxbp1
PAX3 and PAX7 binding protein 1
chr7_+_130865835 0.929 ENSMUST00000075181.4
ENSMUST00000048180.5
Plekha1

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1

chr8_-_111522073 0.914 ENSMUST00000034437.6
ENSMUST00000038193.7
Wdr59

WD repeat domain 59

chr4_-_136956784 0.900 ENSMUST00000030420.8
Epha8
Eph receptor A8
chr13_+_96542727 0.886 ENSMUST00000077672.4
ENSMUST00000109444.2
Col4a3bp

collagen, type IV, alpha 3 (Goodpasture antigen) binding protein

chr8_+_4248188 0.885 ENSMUST00000110993.1
Gm14378
predicted gene 14378
chr17_+_14279506 0.874 ENSMUST00000024660.8
Smoc2
SPARC related modular calcium binding 2
chr4_-_129614254 0.863 ENSMUST00000106037.2
ENSMUST00000179209.1
Dcdc2b

doublecortin domain containing 2b

chr7_-_4778141 0.862 ENSMUST00000094892.5
Il11
interleukin 11
chr6_+_86404336 0.850 ENSMUST00000113713.2
ENSMUST00000113708.1
Tia1

cytotoxic granule-associated RNA binding protein 1

chr17_-_68004075 0.844 ENSMUST00000024840.5
Arhgap28
Rho GTPase activating protein 28
chr2_-_127482499 0.834 ENSMUST00000088538.5
Kcnip3
Kv channel interacting protein 3, calsenilin
chr5_+_107437908 0.830 ENSMUST00000094541.2
Btbd8
BTB (POZ) domain containing 8
chr16_+_32332238 0.827 ENSMUST00000115151.3
Ubxn7
UBX domain protein 7
chr2_-_144527341 0.806 ENSMUST00000163701.1
ENSMUST00000081982.5
Dzank1

double zinc ribbon and ankyrin repeat domains 1

chrX_-_108834303 0.804 ENSMUST00000101283.3
ENSMUST00000150434.1
Brwd3

bromodomain and WD repeat domain containing 3

chr6_+_48395586 0.800 ENSMUST00000114571.1
ENSMUST00000114572.3
ENSMUST00000031815.5
Krba1


KRAB-A domain containing 1


chr3_-_104511812 0.795 ENSMUST00000046316.6
Lrig2
leucine-rich repeats and immunoglobulin-like domains 2
chr5_-_20882072 0.794 ENSMUST00000118174.1
Phtf2
putative homeodomain transcription factor 2
chr2_-_20968526 0.792 ENSMUST00000141298.2
ENSMUST00000125783.2
Arhgap21

Rho GTPase activating protein 21

chr6_+_86404219 0.791 ENSMUST00000095754.3
ENSMUST00000095753.2
Tia1

cytotoxic granule-associated RNA binding protein 1

chr2_-_146511992 0.788 ENSMUST00000109986.2
Ralgapa2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr16_-_91011029 0.783 ENSMUST00000130813.1
Synj1
synaptojanin 1
chr12_+_112760652 0.773 ENSMUST00000063888.3
Pld4
phospholipase D family, member 4
chr2_+_15055274 0.771 ENSMUST00000069870.3
Arl5b
ADP-ribosylation factor-like 5B
chr6_+_86404257 0.767 ENSMUST00000095752.2
ENSMUST00000130967.1
Tia1

cytotoxic granule-associated RNA binding protein 1

chr6_-_39725448 0.747 ENSMUST00000002487.8
Braf
Braf transforming gene
chr15_+_40655020 0.746 ENSMUST00000053467.4
Zfpm2
zinc finger protein, multitype 2
chr11_+_101246405 0.746 ENSMUST00000122006.1
ENSMUST00000151830.1
Ramp2

receptor (calcitonin) activity modifying protein 2

chr10_+_39732364 0.741 ENSMUST00000164763.1
Rev3l
REV3-like, catalytic subunit of DNA polymerase zeta RAD54 like (S. cerevisiae)
chr4_-_154097105 0.740 ENSMUST00000105643.1
ENSMUST00000133533.1
ENSMUST00000097762.4
Trp73


transformation related protein 73


chr5_-_98030727 0.735 ENSMUST00000031281.9
Antxr2
anthrax toxin receptor 2
chr14_+_31217850 0.731 ENSMUST00000090180.2
Sema3g
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
chr7_+_99268338 0.727 ENSMUST00000107100.2
Map6
microtubule-associated protein 6
chrY_-_1286563 0.712 ENSMUST00000091190.5
Ddx3y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr13_-_29984219 0.710 ENSMUST00000146092.1
E2f3
E2F transcription factor 3
chr9_-_82975475 0.693 ENSMUST00000034787.5
Phip
pleckstrin homology domain interacting protein
chr4_+_108460000 0.691 ENSMUST00000097925.2
Zcchc11
zinc finger, CCHC domain containing 11
chr7_+_130865756 0.681 ENSMUST00000120441.1
Plekha1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr14_-_73325773 0.680 ENSMUST00000022701.6
Rb1
retinoblastoma 1
chr4_+_43631935 0.679 ENSMUST00000030191.8
Npr2
natriuretic peptide receptor 2
chr17_-_32788284 0.672 ENSMUST00000159086.2
Zfp871
zinc finger protein 871
chr9_-_88438898 0.670 ENSMUST00000173011.1
ENSMUST00000174806.1
Snx14

sorting nexin 14

chr3_-_108415552 0.666 ENSMUST00000090558.3
Celsr2
cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
chr9_+_91378636 0.658 ENSMUST00000066384.5
Zic4
zinc finger protein of the cerebellum 4
chr11_-_72266596 0.655 ENSMUST00000021161.6
ENSMUST00000140167.1
Slc13a5

solute carrier family 13 (sodium-dependent citrate transporter), member 5

chr14_-_55560340 0.649 ENSMUST00000066106.3
A730061H03Rik
RIKEN cDNA A730061H03 gene
chr2_-_104816696 0.649 ENSMUST00000117237.1
Qser1
glutamine and serine rich 1
chr14_+_25607797 0.648 ENSMUST00000160229.1
Zmiz1
zinc finger, MIZ-type containing 1
chr5_+_105731755 0.640 ENSMUST00000127686.1
Lrrc8d
leucine rich repeat containing 8D
chrX_+_161717498 0.636 ENSMUST00000061514.7
Rai2
retinoic acid induced 2
chr8_+_4243264 0.634 ENSMUST00000110996.1
Map2k7
mitogen-activated protein kinase kinase 7
chrX_+_163909132 0.632 ENSMUST00000033734.7
ENSMUST00000112294.2
Ap1s2

adaptor-related protein complex 1, sigma 2 subunit

chr7_+_51879041 0.630 ENSMUST00000107591.2
Gas2
growth arrest specific 2
chr7_+_30169861 0.629 ENSMUST00000085668.4
Gm5113
predicted gene 5113
chr6_+_52714219 0.629 ENSMUST00000138040.1
ENSMUST00000129660.1
Tax1bp1

Tax1 (human T cell leukemia virus type I) binding protein 1

chr16_+_94370618 0.616 ENSMUST00000117648.1
ENSMUST00000147352.1
ENSMUST00000150346.1
ENSMUST00000155692.1
ENSMUST00000153988.1
ENSMUST00000141856.1
ENSMUST00000152117.1
ENSMUST00000150097.1
ENSMUST00000122895.1
ENSMUST00000151770.1
Ttc3









tetratricopeptide repeat domain 3









chr1_+_191906743 0.615 ENSMUST00000044954.6
Slc30a1
solute carrier family 30 (zinc transporter), member 1
chr1_+_129273344 0.614 ENSMUST00000073527.6
ENSMUST00000040311.7
Thsd7b

thrombospondin, type I, domain containing 7B

chrX_+_137049586 0.612 ENSMUST00000047852.7
Fam199x
family with sequence similarity 199, X-linked
chr5_+_105732063 0.610 ENSMUST00000154807.1
Lrrc8d
leucine rich repeat containing 8D
chr3_+_103279293 0.610 ENSMUST00000029444.6
ENSMUST00000106860.1
Trim33

tripartite motif-containing 33

chr14_-_30353468 0.609 ENSMUST00000112249.1
Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr10_+_81137953 0.607 ENSMUST00000117956.1
Zbtb7a
zinc finger and BTB domain containing 7a
chr19_+_3767953 0.603 ENSMUST00000113970.1
Suv420h1
suppressor of variegation 4-20 homolog 1 (Drosophila)
chr7_-_80403315 0.600 ENSMUST00000147150.1
Furin
furin (paired basic amino acid cleaving enzyme)
chr1_-_133801031 0.589 ENSMUST00000143567.1
Atp2b4
ATPase, Ca++ transporting, plasma membrane 4
chr19_+_42045792 0.588 ENSMUST00000172244.1
ENSMUST00000081714.4
Hoga1

4-hydroxy-2-oxoglutarate aldolase 1

chr16_+_18776839 0.587 ENSMUST00000043577.1
Cldn5
claudin 5
chr11_-_70687917 0.581 ENSMUST00000108545.2
ENSMUST00000120261.1
ENSMUST00000036299.7
ENSMUST00000119120.1
ENSMUST00000100933.3
Camta2




calmodulin binding transcription activator 2




chrX_+_71364901 0.581 ENSMUST00000132837.1
Mtmr1
myotubularin related protein 1
chr8_+_127064107 0.575 ENSMUST00000162536.1
ENSMUST00000026921.6
ENSMUST00000162665.1
ENSMUST00000160766.1
ENSMUST00000162602.1
ENSMUST00000162531.1
ENSMUST00000160581.1
ENSMUST00000161355.1
ENSMUST00000159537.1
Pard3








par-3 (partitioning defective 3) homolog (C. elegans)








chr11_-_100759740 0.575 ENSMUST00000107361.2
Kcnh4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr5_+_135725713 0.574 ENSMUST00000127096.1
Por
P450 (cytochrome) oxidoreductase
chr9_+_108826320 0.574 ENSMUST00000024238.5
Celsr3
cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
chr7_-_111779963 0.573 ENSMUST00000049430.8
ENSMUST00000106663.1
Galnt18

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 18

chr15_+_80287234 0.572 ENSMUST00000160424.1
Cacna1i
calcium channel, voltage-dependent, alpha 1I subunit
chr1_+_59764264 0.566 ENSMUST00000087435.5
Bmpr2
bone morphogenetic protein receptor, type II (serine/threonine kinase)
chr9_-_88438940 0.564 ENSMUST00000165315.1
ENSMUST00000173039.1
Snx14

sorting nexin 14

chr15_-_78803015 0.558 ENSMUST00000164826.1
Card10
caspase recruitment domain family, member 10
chr9_-_44721383 0.557 ENSMUST00000148929.1
ENSMUST00000123406.1
Phldb1

pleckstrin homology-like domain, family B, member 1

chrX_+_73064787 0.554 ENSMUST00000060418.6
Pnma3
paraneoplastic antigen MA3
chr15_-_99820072 0.553 ENSMUST00000109024.2
Lima1
LIM domain and actin binding 1
chr11_-_116024489 0.552 ENSMUST00000016703.7
H3f3b
H3 histone, family 3B
chr5_+_139543889 0.545 ENSMUST00000174792.1
ENSMUST00000031523.8
Uncx

UNC homeobox

chr2_-_148408146 0.539 ENSMUST00000099270.3
Thbd
thrombomodulin
chr9_+_46012810 0.538 ENSMUST00000126865.1
Sik3
SIK family kinase 3
chr10_-_26373956 0.537 ENSMUST00000105519.3
ENSMUST00000040219.6
L3mbtl3

l(3)mbt-like 3 (Drosophila)

chr3_-_53463234 0.537 ENSMUST00000056749.7
Nhlrc3
NHL repeat containing 3
chrX_+_71663665 0.536 ENSMUST00000070449.5
Gpr50
G-protein-coupled receptor 50
chr1_-_132707304 0.535 ENSMUST00000043189.7
Nfasc
neurofascin
chr10_-_63023847 0.527 ENSMUST00000119814.2
Hnrnph3
heterogeneous nuclear ribonucleoprotein H3
chr11_-_85139939 0.527 ENSMUST00000108075.2
Usp32
ubiquitin specific peptidase 32
chr19_-_5688149 0.527 ENSMUST00000068169.5
Pcnxl3
pecanex-like 3 (Drosophila)
chr10_+_80356459 0.525 ENSMUST00000039836.8
ENSMUST00000105351.1
Plk5

polo-like kinase 5

chr7_+_51878967 0.524 ENSMUST00000051912.6
Gas2
growth arrest specific 2
chr11_+_116280939 0.519 ENSMUST00000055872.2
Galr2
galanin receptor 2
chr13_-_9764943 0.517 ENSMUST00000110634.1
Zmynd11
zinc finger, MYND domain containing 11
chr2_-_119477613 0.514 ENSMUST00000110808.1
ENSMUST00000049920.7
Ino80

INO80 homolog (S. cerevisiae)

chr7_+_90442729 0.512 ENSMUST00000061767.4
ENSMUST00000107206.1
Crebzf

CREB/ATF bZIP transcription factor

chr19_+_46397009 0.510 ENSMUST00000118440.1
Sufu
suppressor of fused homolog (Drosophila)
chr6_+_61180313 0.503 ENSMUST00000126214.1
Ccser1
coiled-coil serine rich 1
chr8_-_105637403 0.500 ENSMUST00000182046.1
Gm5914
predicted gene 5914
chrX_-_7574120 0.497 ENSMUST00000045924.7
ENSMUST00000115742.2
ENSMUST00000150787.1
Ppp1r3f


protein phosphatase 1, regulatory (inhibitor) subunit 3F


chr14_-_56811464 0.496 ENSMUST00000173954.1
Zmym5
zinc finger, MYM-type 5
chr17_+_4994904 0.495 ENSMUST00000092723.4
ENSMUST00000115797.2
Arid1b

AT rich interactive domain 1B (SWI-like)

chr11_+_115900125 0.489 ENSMUST00000142089.1
ENSMUST00000131566.1
Smim5

small integral membrane protein 5

chr8_-_126475062 0.483 ENSMUST00000170518.1
Gm17296
predicted gene, 17296
chrX_+_52791179 0.482 ENSMUST00000101588.1
Ccdc160
coiled-coil domain containing 160
chr8_-_47289394 0.482 ENSMUST00000079195.5
Stox2
storkhead box 2
chr14_-_20794009 0.479 ENSMUST00000100837.3
ENSMUST00000080440.6
ENSMUST00000071816.6
Camk2g


calcium/calmodulin-dependent protein kinase II gamma


chr4_+_43632185 0.479 ENSMUST00000107874.2
Npr2
natriuretic peptide receptor 2
chr6_+_7844806 0.477 ENSMUST00000040159.4
C1galt1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr9_-_103480328 0.472 ENSMUST00000124310.2
Bfsp2
beaded filament structural protein 2, phakinin
chr14_-_78536854 0.472 ENSMUST00000022593.5
Akap11
A kinase (PRKA) anchor protein 11
chr13_+_31806627 0.469 ENSMUST00000062292.2
Foxc1
forkhead box C1
chrX_+_57053549 0.468 ENSMUST00000114751.2
ENSMUST00000088652.5
Htatsf1

HIV TAT specific factor 1

chr12_+_83632208 0.461 ENSMUST00000048155.9
ENSMUST00000182618.1
ENSMUST00000183154.1
ENSMUST00000182036.1
ENSMUST00000182347.1
Rbm25




RNA binding motif protein 25




chr11_-_109473220 0.460 ENSMUST00000070872.6
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr7_+_96211656 0.459 ENSMUST00000107165.1
Tenm4
teneurin transmembrane protein 4
chr13_+_74350299 0.457 ENSMUST00000022063.7
Ccdc127
coiled-coil domain containing 127
chr15_-_79742493 0.454 ENSMUST00000100439.3
Sun2
Sad1 and UNC84 domain containing 2
chr17_+_56326045 0.452 ENSMUST00000139679.1
ENSMUST00000025036.4
ENSMUST00000086835.5
Kdm4b


lysine (K)-specific demethylase 4B


chr1_-_38129618 0.447 ENSMUST00000027251.6
Rev1
REV1 homolog (S. cerevisiae)
chr11_+_87760533 0.447 ENSMUST00000039627.5
ENSMUST00000100644.3
Bzrap1

benzodiazepine receptor associated protein 1

chr10_-_49788743 0.447 ENSMUST00000105483.1
ENSMUST00000105487.1
Grik2

glutamate receptor, ionotropic, kainate 2 (beta 2)

chr14_-_56811716 0.446 ENSMUST00000039812.9
ENSMUST00000111285.2
Zmym5

zinc finger, MYM-type 5

chr4_+_137277489 0.446 ENSMUST00000045747.4
Wnt4
wingless-related MMTV integration site 4
chr9_+_46012822 0.445 ENSMUST00000120463.2
ENSMUST00000120247.1
Sik3

SIK family kinase 3

chr5_+_117781017 0.441 ENSMUST00000138579.2
Nos1
nitric oxide synthase 1, neuronal
chr16_+_32914094 0.438 ENSMUST00000023491.6
ENSMUST00000170899.1
ENSMUST00000171118.1
ENSMUST00000170201.1
ENSMUST00000165616.1
ENSMUST00000135193.2
Lrch3





leucine-rich repeats and calponin homology (CH) domain containing 3





chr17_-_6961156 0.432 ENSMUST00000063683.6
Tagap1
T cell activation GTPase activating protein 1
chr11_-_106788845 0.431 ENSMUST00000123339.1
Ddx5
DEAD (Asp-Glu-Ala-Asp) box polypeptide 5
chr1_+_36511867 0.430 ENSMUST00000001166.7
ENSMUST00000097776.3
Cnnm3

cyclin M3

chrX_+_140956892 0.423 ENSMUST00000112971.1
Atg4a
autophagy related 4A, cysteine peptidase
chr11_-_86544754 0.422 ENSMUST00000138810.1
ENSMUST00000058286.2
ENSMUST00000154617.1
Rps6kb1


ribosomal protein S6 kinase, polypeptide 1


chr17_+_25786566 0.422 ENSMUST00000095500.4
Ccdc78
coiled-coil domain containing 78
chr10_+_82985473 0.408 ENSMUST00000040110.7
Chst11
carbohydrate sulfotransferase 11
chrX_+_71364745 0.402 ENSMUST00000114601.1
ENSMUST00000146213.1
ENSMUST00000015358.1
Mtmr1


myotubularin related protein 1


chr6_+_87981683 0.400 ENSMUST00000143871.1
ENSMUST00000153372.1
Gm5577

predicted gene 5577

chr14_+_31001383 0.391 ENSMUST00000168584.1
Glt8d1
glycosyltransferase 8 domain containing 1
chr16_-_30388530 0.388 ENSMUST00000100013.2
ENSMUST00000061350.6
Atp13a3

ATPase type 13A3

chr16_+_20733104 0.387 ENSMUST00000115423.1
ENSMUST00000007171.6
Chrd

chordin

chr11_+_97799772 0.386 ENSMUST00000129558.1
Lasp1
LIM and SH3 protein 1
chr17_+_86963279 0.386 ENSMUST00000139344.1
Rhoq
ras homolog gene family, member Q
chr14_+_121035194 0.386 ENSMUST00000135010.1
Farp1
FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived)
chr14_-_34374617 0.385 ENSMUST00000023826.4
Sncg
synuclein, gamma
chrX_+_163908982 0.381 ENSMUST00000069041.8
Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr4_-_134853294 0.374 ENSMUST00000030628.8
Tmem57
transmembrane protein 57
chr1_-_163403627 0.373 ENSMUST00000045138.4
Gorab
golgin, RAB6-interacting
chr10_-_78487842 0.370 ENSMUST00000069431.4
Gm9978
predicted gene 9978
chr1_+_135729147 0.366 ENSMUST00000027677.7
Csrp1
cysteine and glycine-rich protein 1
chr7_+_99267428 0.365 ENSMUST00000068973.4
ENSMUST00000122101.1
Map6

microtubule-associated protein 6

chr3_+_86224665 0.365 ENSMUST00000107635.1
Lrba
LPS-responsive beige-like anchor
chr9_-_108263887 0.363 ENSMUST00000166905.1
ENSMUST00000080435.2
Dag1

dystroglycan 1

chr5_+_115506668 0.355 ENSMUST00000067268.8
ENSMUST00000086523.3
Pxn

paxillin

chr1_-_172082757 0.354 ENSMUST00000003550.4
Ncstn
nicastrin
chr11_+_85832551 0.351 ENSMUST00000000095.6
Tbx2
T-box 2
chr5_+_92137896 0.349 ENSMUST00000031355.6
Uso1
USO1 vesicle docking factor
chr17_+_34197715 0.348 ENSMUST00000173441.1
ENSMUST00000025196.8
Psmb8

proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.5 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.5 2.5 GO:0060178 regulation of exocyst localization(GO:0060178)
0.4 1.4 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.3 1.0 GO:0060023 soft palate development(GO:0060023)
0.3 1.9 GO:0002934 desmosome organization(GO:0002934)
0.3 0.9 GO:0035621 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
0.3 0.3 GO:0048859 formation of anatomical boundary(GO:0048859)
0.3 0.3 GO:1905072 cardiac jelly development(GO:1905072)
0.3 0.8 GO:1904978 regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980)
0.3 0.5 GO:1902608 regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.3 1.0 GO:1901204 regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204)
0.3 1.8 GO:0035754 B cell chemotaxis(GO:0035754)
0.2 0.7 GO:0003195 tricuspid valve formation(GO:0003195) right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.2 1.0 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.2 2.4 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.2 0.7 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.2 2.2 GO:0015838 proline transport(GO:0015824) amino-acid betaine transport(GO:0015838)
0.2 1.3 GO:0019695 choline metabolic process(GO:0019695)
0.2 0.8 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.2 0.6 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.2 1.6 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.2 1.2 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.2 0.6 GO:0014916 regulation of lung blood pressure(GO:0014916) negative regulation of cell proliferation involved in heart morphogenesis(GO:2000137) cell proliferation involved in heart valve development(GO:2000793)
0.2 0.5 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.2 1.0 GO:0003383 apical constriction(GO:0003383)
0.2 0.5 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.2 0.7 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.2 0.7 GO:0015744 succinate transport(GO:0015744)
0.2 3.3 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.2 1.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 0.8 GO:0051684 maintenance of Golgi location(GO:0051684)
0.2 0.5 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256) response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
0.2 0.6 GO:0090472 dibasic protein processing(GO:0090472)
0.2 0.3 GO:0003273 cell migration involved in endocardial cushion formation(GO:0003273)
0.2 0.5 GO:0060912 cardiac cell fate specification(GO:0060912)
0.2 0.6 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.1 0.4 GO:0060126 somatotropin secreting cell differentiation(GO:0060126) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129) dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) renal vesicle induction(GO:0072034) regulation of testosterone biosynthetic process(GO:2000224)
0.1 0.6 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.1 0.6 GO:0046210 nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.1 0.6 GO:1902340 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.1 0.5 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.8 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 1.2 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.7 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 2.7 GO:0060579 ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581)
0.1 0.7 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 0.4 GO:0007521 muscle cell fate determination(GO:0007521) mammary placode formation(GO:0060596)
0.1 0.3 GO:0070375 ERK5 cascade(GO:0070375)
0.1 0.3 GO:1900149 positive regulation of Schwann cell migration(GO:1900149)
0.1 0.3 GO:0015697 quaternary ammonium group transport(GO:0015697)
0.1 0.4 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.1 1.0 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.1 0.6 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1 0.6 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.1 1.6 GO:0008209 androgen metabolic process(GO:0008209)
0.1 0.7 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 0.6 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.5 GO:0090292 nuclear migration along microfilament(GO:0031022) nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.9 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1 0.7 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.4 GO:0051697 protein delipidation(GO:0051697)
0.1 2.1 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 0.2 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1 0.3 GO:0032901 positive regulation of neurotrophin production(GO:0032901)
0.1 0.5 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.8 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1 0.9 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.1 0.4 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.1 0.3 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.1 0.6 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 0.5 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.1 0.4 GO:0048703 embryonic viscerocranium morphogenesis(GO:0048703)
0.1 0.3 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.1 0.6 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.1 0.4 GO:0098535 de novo centriole assembly(GO:0098535)
0.1 0.3 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.1 1.0 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 1.5 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.3 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.1 0.6 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 0.4 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1 1.1 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.1 0.2 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103) negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
0.1 0.2 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.1 0.5 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.2 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.5 GO:0002347 response to tumor cell(GO:0002347)
0.0 0.2 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 0.2 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.0 3.0 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.5 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 0.2 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.3 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.6 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 1.0 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 1.4 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.2 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.5 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.0 0.5 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.2 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.0 0.6 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.1 GO:0072720 response to sorbitol(GO:0072708) response to dithiothreitol(GO:0072720)
0.0 0.1 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.3 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.4 GO:1901620 regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620)
0.0 0.5 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.8 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.5 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 1.7 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.0 1.0 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.0 0.9 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.1 GO:0006545 glycine biosynthetic process(GO:0006545)
0.0 0.1 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.0 2.3 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.1 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 0.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.4 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.6 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0 0.1 GO:0001844 protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:0001844)
0.0 0.2 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.2 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.5 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.0 0.2 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.2 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.1 GO:0001956 positive regulation of neurotransmitter secretion(GO:0001956)
0.0 0.3 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.4 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.8 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0 0.7 GO:0030517 negative regulation of axon extension(GO:0030517)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.4 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.1 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.3 GO:0045056 transcytosis(GO:0045056)
0.0 0.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.1 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 3.9 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 1.0 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.0 0.5 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 1.8 GO:0051225 spindle assembly(GO:0051225)
0.0 0.2 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.0 0.2 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.1 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.2 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.0 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.8 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.3 GO:1903077 negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.1 GO:0030157 pancreatic juice secretion(GO:0030157)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.0 GO:0043181 vacuolar sequestering(GO:0043181)
0.0 0.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0048148 behavioral response to cocaine(GO:0048148)
0.0 0.5 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.5 GO:1901998 toxin transport(GO:1901998)
0.0 0.7 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 1.4 GO:0098656 anion transmembrane transport(GO:0098656)
0.0 0.1 GO:0060482 lobar bronchus development(GO:0060482)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.4 GO:0097165 nuclear stress granule(GO:0097165)
0.2 1.4 GO:0008091 spectrin(GO:0008091)
0.2 3.0 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 0.7 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1 0.7 GO:0035189 Rb-E2F complex(GO:0035189)
0.1 0.5 GO:0097454 Schwann cell microvillus(GO:0097454)
0.1 1.0 GO:0033269 internode region of axon(GO:0033269)
0.1 0.7 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 2.9 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.7 GO:0016011 dystroglycan complex(GO:0016011)
0.1 1.3 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.6 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 0.9 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.4 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 0.4 GO:0098536 deuterosome(GO:0098536)
0.1 1.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 1.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.5 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.3 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 0.8 GO:0005614 interstitial matrix(GO:0005614)
0.1 1.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.9 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.4 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.4 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.3 GO:0060091 kinocilium(GO:0060091)
0.0 0.3 GO:0001940 male pronucleus(GO:0001940)
0.0 0.6 GO:0045180 basal cortex(GO:0045180)
0.0 2.3 GO:0005871 kinesin complex(GO:0005871)
0.0 0.2 GO:0044305 calyx of Held(GO:0044305)
0.0 0.5 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.5 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.5 GO:0031011 Ino80 complex(GO:0031011)
0.0 1.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 2.4 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.3 GO:0034464 BBSome(GO:0034464)
0.0 0.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 1.4 GO:0016459 myosin complex(GO:0016459)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 2.1 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.2 GO:0000796 condensin complex(GO:0000796)
0.0 0.1 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.4 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.6 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 1.0 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 1.1 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.6 GO:0030315 T-tubule(GO:0030315)
0.0 0.2 GO:0032420 stereocilium(GO:0032420)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.4 1.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.3 1.3 GO:0004104 cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.3 1.8 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.3 2.2 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.2 1.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.2 1.4 GO:0045545 syndecan binding(GO:0045545)
0.2 0.7 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.2 2.5 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.2 1.1 GO:0097001 ceramide binding(GO:0097001)
0.2 0.5 GO:0008502 melatonin receptor activity(GO:0008502)
0.2 0.8 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1 1.0 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.7 GO:0097643 amylin receptor activity(GO:0097643)
0.1 0.4 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.6 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 0.4 GO:0035500 MH2 domain binding(GO:0035500)
0.1 0.6 GO:0016708 nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726)
0.1 0.6 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.4 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 1.0 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.7 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 0.5 GO:0004966 galanin receptor activity(GO:0004966)
0.1 0.6 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 0.5 GO:2001069 glycogen binding(GO:2001069)
0.1 0.9 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 1.5 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.3 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.1 0.5 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.4 GO:0034481 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537) chondroitin sulfotransferase activity(GO:0034481)
0.1 0.9 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 0.8 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.9 GO:0036122 BMP binding(GO:0036122)
0.1 2.1 GO:0030506 ankyrin binding(GO:0030506)
0.1 0.6 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 2.8 GO:0032452 histone demethylase activity(GO:0032452)
0.1 0.4 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.9 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.7 GO:0043237 laminin-1 binding(GO:0043237)
0.1 1.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 0.2 GO:0001565 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
0.1 1.7 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 1.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.5 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 0.6 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 2.0 GO:0017091 AU-rich element binding(GO:0017091)
0.1 0.2 GO:0097677 STAT family protein binding(GO:0097677)
0.1 1.0 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 1.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.3 GO:0048403 neurotrophin binding(GO:0043121) brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.5 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.5 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0 0.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.5 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.3 GO:0000150 recombinase activity(GO:0000150)
0.0 0.3 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.9 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)
0.0 0.5 GO:0043495 protein anchor(GO:0043495)
0.0 1.0 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.2 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.1 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.7 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.6 GO:0070410 co-SMAD binding(GO:0070410)
0.0 2.3 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.5 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.4 GO:0017166 vinculin binding(GO:0017166)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 1.0 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 5.6 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 1.4 GO:0003774 motor activity(GO:0003774)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.4 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.6 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 1.7 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.3 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 4.5 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.6 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.1 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.0 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.3 GO:0042805 actinin binding(GO:0042805)
0.0 1.4 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.4 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.1 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.2 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.1 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 PID_ALK2_PATHWAY ALK2 signaling events
0.1 0.3 PID_ALK1_PATHWAY ALK1 signaling events
0.1 1.4 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.1 0.5 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.1 2.3 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 0.7 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.3 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.0 2.5 PID_PI3KCI_PATHWAY Class I PI3K signaling events
0.0 0.9 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 2.0 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 1.6 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.5 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.3 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 0.3 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.0 1.5 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.0 1.0 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.0 0.2 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.4 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 0.5 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.9 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.3 ST_GA12_PATHWAY G alpha 12 Pathway
0.0 0.5 PID_ERBB4_PATHWAY ErbB4 signaling events
0.0 0.8 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.0 0.7 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 0.6 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 0.6 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.0 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.0 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.2 1.8 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 0.5 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.1 1.3 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 0.6 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 0.7 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 0.7 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 0.9 REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR Genes involved in Regulated proteolysis of p75NTR
0.1 0.7 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 1.3 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.1 0.3 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 1.2 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.6 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.3 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.0 1.8 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.7 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 1.4 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.6 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.6 REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.4 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.4 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.1 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.6 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.4 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.2 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.2 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.1 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.4 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.6 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.5 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.2 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle