Motif ID: Hsf4
Z-value: 0.820

Transcription factors associated with Hsf4:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Hsf4 | ENSMUSG00000033249.4 | Hsf4 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 2.6 | GO:1900041 | negative regulation of interleukin-2 secretion(GO:1900041) |
0.8 | 4.6 | GO:1901164 | negative regulation of trophoblast cell migration(GO:1901164) |
0.8 | 2.3 | GO:0035799 | ureter maturation(GO:0035799) |
0.7 | 4.4 | GO:0045583 | regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585) |
0.7 | 2.8 | GO:0044565 | dendritic cell proliferation(GO:0044565) |
0.5 | 2.0 | GO:0060715 | syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715) |
0.4 | 2.1 | GO:0002457 | T cell antigen processing and presentation(GO:0002457) |
0.4 | 1.2 | GO:0033364 | mast cell secretory granule organization(GO:0033364) |
0.4 | 1.1 | GO:0010845 | positive regulation of reciprocal meiotic recombination(GO:0010845) |
0.3 | 1.0 | GO:0002636 | positive regulation of germinal center formation(GO:0002636) |
0.3 | 1.3 | GO:1901252 | regulation of intracellular transport of viral material(GO:1901252) |
0.3 | 0.9 | GO:0032918 | polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918) |
0.3 | 0.9 | GO:0090526 | regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526) |
0.3 | 1.1 | GO:0019919 | peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919) |
0.3 | 0.8 | GO:1903538 | meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538) |
0.3 | 1.8 | GO:0045650 | negative regulation of macrophage differentiation(GO:0045650) |
0.2 | 1.2 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
0.2 | 1.0 | GO:0055071 | cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071) |
0.2 | 0.7 | GO:1901079 | positive regulation of relaxation of muscle(GO:1901079) |
0.2 | 0.7 | GO:1902605 | heterotrimeric G-protein complex assembly(GO:1902605) |
0.2 | 1.0 | GO:1902683 | regulation of receptor localization to synapse(GO:1902683) |
0.2 | 1.2 | GO:0007021 | tubulin complex assembly(GO:0007021) |
0.2 | 1.8 | GO:0042769 | DNA damage response, detection of DNA damage(GO:0042769) |
0.2 | 0.8 | GO:0007412 | axon target recognition(GO:0007412) |
0.2 | 1.2 | GO:0090383 | phagosome acidification(GO:0090383) |
0.2 | 0.7 | GO:1900533 | medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535) |
0.2 | 0.7 | GO:0002484 | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485) |
0.2 | 1.0 | GO:0002606 | positive regulation of dendritic cell antigen processing and presentation(GO:0002606) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) |
0.2 | 0.8 | GO:0035617 | stress granule disassembly(GO:0035617) |
0.2 | 2.1 | GO:1902018 | regulation of mitotic spindle assembly(GO:1901673) negative regulation of cilium assembly(GO:1902018) |
0.2 | 0.2 | GO:0051012 | microtubule sliding(GO:0051012) |
0.1 | 0.4 | GO:0071492 | cellular response to UV-A(GO:0071492) |
0.1 | 0.6 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
0.1 | 0.4 | GO:0035928 | rRNA import into mitochondrion(GO:0035928) |
0.1 | 0.8 | GO:0034145 | positive regulation of toll-like receptor 4 signaling pathway(GO:0034145) |
0.1 | 0.8 | GO:0042535 | positive regulation of tumor necrosis factor biosynthetic process(GO:0042535) |
0.1 | 0.5 | GO:2000048 | negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048) |
0.1 | 0.6 | GO:0035063 | nuclear speck organization(GO:0035063) |
0.1 | 1.1 | GO:0006620 | posttranslational protein targeting to membrane(GO:0006620) |
0.1 | 0.2 | GO:0035771 | interleukin-4-mediated signaling pathway(GO:0035771) |
0.1 | 1.3 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
0.1 | 0.8 | GO:0019348 | dolichol metabolic process(GO:0019348) |
0.1 | 0.8 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
0.1 | 0.9 | GO:0006729 | tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146) |
0.1 | 0.8 | GO:0098707 | ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707) |
0.1 | 0.5 | GO:0042891 | antibiotic transport(GO:0042891) dipeptide transport(GO:0042938) |
0.1 | 0.3 | GO:0035963 | response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963) |
0.1 | 0.7 | GO:0001955 | blood vessel maturation(GO:0001955) |
0.1 | 0.9 | GO:0006027 | glycosaminoglycan catabolic process(GO:0006027) |
0.1 | 0.4 | GO:0060178 | regulation of exocyst localization(GO:0060178) |
0.1 | 0.4 | GO:0070197 | meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240) |
0.1 | 0.3 | GO:0015793 | glycerol transport(GO:0015793) |
0.1 | 0.2 | GO:1904154 | protein localization to endoplasmic reticulum exit site(GO:0070973) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154) |
0.1 | 0.8 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
0.1 | 0.3 | GO:0060316 | positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) |
0.1 | 0.5 | GO:0015862 | uridine transport(GO:0015862) |
0.1 | 0.4 | GO:0097527 | necroptotic signaling pathway(GO:0097527) |
0.1 | 0.2 | GO:0009838 | abscission(GO:0009838) |
0.1 | 0.4 | GO:2000298 | regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298) |
0.1 | 1.4 | GO:0016486 | peptide hormone processing(GO:0016486) |
0.1 | 0.4 | GO:0060907 | positive regulation of macrophage cytokine production(GO:0060907) |
0.1 | 0.2 | GO:0000720 | pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) |
0.1 | 0.2 | GO:0036233 | glycine import(GO:0036233) |
0.1 | 0.6 | GO:0035887 | aortic smooth muscle cell differentiation(GO:0035887) |
0.1 | 0.5 | GO:0051036 | regulation of endosome size(GO:0051036) receptor internalization involved in canonical Wnt signaling pathway(GO:2000286) |
0.1 | 0.9 | GO:0035881 | amacrine cell differentiation(GO:0035881) |
0.1 | 0.3 | GO:0090666 | scaRNA localization to Cajal body(GO:0090666) |
0.1 | 0.6 | GO:0090315 | negative regulation of protein targeting to membrane(GO:0090315) |
0.1 | 0.9 | GO:0060052 | neurofilament cytoskeleton organization(GO:0060052) |
0.1 | 0.7 | GO:0090037 | positive regulation of protein kinase C signaling(GO:0090037) |
0.1 | 0.4 | GO:0019695 | choline metabolic process(GO:0019695) |
0.1 | 0.2 | GO:0031554 | regulation of DNA-templated transcription, termination(GO:0031554) |
0.1 | 0.2 | GO:0032627 | interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) |
0.1 | 1.7 | GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I(GO:0002474) |
0.1 | 0.7 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
0.1 | 0.6 | GO:0034551 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033) |
0.0 | 0.2 | GO:0021564 | glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564) |
0.0 | 0.4 | GO:0071361 | cellular response to ethanol(GO:0071361) |
0.0 | 0.2 | GO:0002188 | translation reinitiation(GO:0002188) |
0.0 | 0.8 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
0.0 | 0.1 | GO:0019043 | establishment of viral latency(GO:0019043) |
0.0 | 0.2 | GO:0060903 | positive regulation of meiosis I(GO:0060903) |
0.0 | 0.3 | GO:0048254 | snoRNA localization(GO:0048254) |
0.0 | 0.4 | GO:0071318 | cellular response to ATP(GO:0071318) |
0.0 | 0.4 | GO:0060766 | negative regulation of androgen receptor signaling pathway(GO:0060766) |
0.0 | 0.5 | GO:0035337 | fatty-acyl-CoA metabolic process(GO:0035337) |
0.0 | 0.1 | GO:0048550 | negative regulation of pinocytosis(GO:0048550) |
0.0 | 0.7 | GO:0048240 | sperm capacitation(GO:0048240) |
0.0 | 0.4 | GO:0030948 | negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) |
0.0 | 0.7 | GO:0051531 | NFAT protein import into nucleus(GO:0051531) |
0.0 | 0.1 | GO:0002842 | T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) positive regulation of T cell mediated immune response to tumor cell(GO:0002842) protein import into mitochondrial intermembrane space(GO:0045041) |
0.0 | 0.7 | GO:0071378 | growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378) |
0.0 | 0.4 | GO:0006228 | UTP biosynthetic process(GO:0006228) |
0.0 | 0.7 | GO:0070286 | axonemal dynein complex assembly(GO:0070286) |
0.0 | 0.4 | GO:0061299 | retina vasculature morphogenesis in camera-type eye(GO:0061299) |
0.0 | 0.3 | GO:0043117 | positive regulation of vascular permeability(GO:0043117) |
0.0 | 1.8 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
0.0 | 0.2 | GO:0061450 | trophoblast cell migration(GO:0061450) regulation of trophoblast cell migration(GO:1901163) positive regulation of trophoblast cell migration(GO:1901165) |
0.0 | 0.2 | GO:0006590 | thyroid hormone generation(GO:0006590) |
0.0 | 0.3 | GO:0070131 | positive regulation of mitochondrial translation(GO:0070131) |
0.0 | 0.3 | GO:0010650 | positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
0.0 | 0.4 | GO:0034244 | negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244) |
0.0 | 0.4 | GO:0007602 | phototransduction(GO:0007602) |
0.0 | 0.8 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
0.0 | 0.1 | GO:0032364 | oxygen homeostasis(GO:0032364) |
0.0 | 0.1 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
0.0 | 0.4 | GO:0033599 | regulation of mammary gland epithelial cell proliferation(GO:0033599) |
0.0 | 0.9 | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146) |
0.0 | 0.1 | GO:0016598 | protein arginylation(GO:0016598) |
0.0 | 0.6 | GO:0045103 | intermediate filament-based process(GO:0045103) |
0.0 | 0.3 | GO:0010818 | T cell chemotaxis(GO:0010818) |
0.0 | 0.8 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.0 | 0.6 | GO:0001523 | retinoid metabolic process(GO:0001523) |
0.0 | 0.1 | GO:0042359 | vitamin D metabolic process(GO:0042359) |
0.0 | 0.0 | GO:1900740 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) |
0.0 | 0.3 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
0.0 | 1.3 | GO:0006749 | glutathione metabolic process(GO:0006749) |
0.0 | 1.0 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
0.0 | 1.7 | GO:0008543 | fibroblast growth factor receptor signaling pathway(GO:0008543) |
0.0 | 0.5 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
0.0 | 0.1 | GO:0046598 | positive regulation of viral entry into host cell(GO:0046598) |
0.0 | 1.2 | GO:0032024 | positive regulation of insulin secretion(GO:0032024) |
0.0 | 0.2 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
0.0 | 0.1 | GO:0048227 | plasma membrane to endosome transport(GO:0048227) |
0.0 | 0.0 | GO:0006434 | seryl-tRNA aminoacylation(GO:0006434) |
0.0 | 0.2 | GO:0046597 | negative regulation of viral entry into host cell(GO:0046597) |
0.0 | 0.4 | GO:0021702 | cerebellar Purkinje cell differentiation(GO:0021702) |
0.0 | 0.5 | GO:0007131 | reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825) |
0.0 | 0.0 | GO:2000812 | response to rapamycin(GO:1901355) regulation of barbed-end actin filament capping(GO:2000812) |
0.0 | 0.5 | GO:0070232 | regulation of T cell apoptotic process(GO:0070232) |
0.0 | 0.2 | GO:0030968 | endoplasmic reticulum unfolded protein response(GO:0030968) |
0.0 | 0.1 | GO:0016584 | nucleosome positioning(GO:0016584) |
0.0 | 0.1 | GO:1904751 | positive regulation of protein localization to nucleolus(GO:1904751) |
0.0 | 0.6 | GO:0000266 | mitochondrial fission(GO:0000266) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 4.4 | GO:0097226 | sperm mitochondrial sheath(GO:0097226) |
0.3 | 2.0 | GO:0097512 | cardiac myofibril(GO:0097512) |
0.2 | 0.8 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
0.2 | 2.4 | GO:0042612 | MHC class I protein complex(GO:0042612) |
0.2 | 0.7 | GO:0008282 | ATP-sensitive potassium channel complex(GO:0008282) |
0.2 | 1.1 | GO:0033503 | HULC complex(GO:0033503) |
0.2 | 0.5 | GO:0098842 | postsynaptic early endosome(GO:0098842) |
0.1 | 0.9 | GO:0000938 | GARP complex(GO:0000938) |
0.1 | 1.0 | GO:0042613 | MHC class II protein complex(GO:0042613) |
0.1 | 1.2 | GO:0042629 | mast cell granule(GO:0042629) |
0.1 | 0.9 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
0.1 | 0.7 | GO:0005955 | calcineurin complex(GO:0005955) |
0.1 | 1.4 | GO:0046930 | pore complex(GO:0046930) |
0.1 | 0.8 | GO:0031415 | NatA complex(GO:0031415) |
0.1 | 0.8 | GO:0097433 | dense body(GO:0097433) |
0.1 | 0.5 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
0.1 | 3.9 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
0.1 | 1.0 | GO:0042588 | zymogen granule(GO:0042588) |
0.1 | 0.4 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) |
0.1 | 1.0 | GO:0000800 | lateral element(GO:0000800) |
0.1 | 0.4 | GO:0031467 | Cul7-RING ubiquitin ligase complex(GO:0031467) |
0.1 | 0.8 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
0.0 | 0.2 | GO:0005784 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
0.0 | 1.1 | GO:0005865 | striated muscle thin filament(GO:0005865) |
0.0 | 0.8 | GO:0035253 | ciliary rootlet(GO:0035253) |
0.0 | 0.3 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
0.0 | 0.2 | GO:0005785 | signal recognition particle receptor complex(GO:0005785) |
0.0 | 0.6 | GO:0071564 | npBAF complex(GO:0071564) |
0.0 | 0.3 | GO:0042382 | paraspeckles(GO:0042382) |
0.0 | 0.7 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
0.0 | 1.2 | GO:0005637 | nuclear inner membrane(GO:0005637) |
0.0 | 0.5 | GO:0043196 | varicosity(GO:0043196) |
0.0 | 0.1 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
0.0 | 0.2 | GO:0060091 | kinocilium(GO:0060091) |
0.0 | 0.3 | GO:0061700 | GATOR2 complex(GO:0061700) |
0.0 | 2.3 | GO:0072562 | blood microparticle(GO:0072562) |
0.0 | 0.1 | GO:0048269 | methionine adenosyltransferase complex(GO:0048269) |
0.0 | 0.3 | GO:0005922 | connexon complex(GO:0005922) |
0.0 | 0.4 | GO:0016471 | vacuolar proton-transporting V-type ATPase complex(GO:0016471) |
0.0 | 0.2 | GO:0090543 | Flemming body(GO:0090543) |
0.0 | 0.2 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
0.0 | 0.1 | GO:0097361 | CIA complex(GO:0097361) |
0.0 | 0.6 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
0.0 | 0.0 | GO:0036379 | myofilament(GO:0036379) |
0.0 | 0.3 | GO:0071339 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
0.0 | 2.4 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.0 | 1.2 | GO:0045335 | phagocytic vesicle(GO:0045335) |
0.0 | 0.1 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
0.0 | 0.3 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
0.0 | 0.6 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
0.0 | 0.3 | GO:0031526 | brush border membrane(GO:0031526) |
0.0 | 2.2 | GO:0030017 | sarcomere(GO:0030017) |
0.0 | 1.0 | GO:0001669 | acrosomal vesicle(GO:0001669) |
0.0 | 0.3 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
0.0 | 0.4 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
0.0 | 0.2 | GO:0005614 | interstitial matrix(GO:0005614) |
0.0 | 0.5 | GO:0035869 | ciliary transition zone(GO:0035869) |
0.0 | 0.7 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
0.0 | 1.8 | GO:0030141 | secretory granule(GO:0030141) |
0.0 | 0.8 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
0.0 | 0.3 | GO:0005876 | spindle microtubule(GO:0005876) |
0.0 | 0.0 | GO:0031074 | nucleocytoplasmic shuttling complex(GO:0031074) |
0.0 | 0.1 | GO:0005921 | gap junction(GO:0005921) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 4.6 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
0.6 | 4.4 | GO:0030911 | TPR domain binding(GO:0030911) |
0.4 | 1.9 | GO:0004028 | 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) |
0.4 | 2.6 | GO:0043199 | sulfate binding(GO:0043199) |
0.3 | 0.9 | GO:0004145 | diamine N-acetyltransferase activity(GO:0004145) |
0.3 | 0.9 | GO:0016262 | protein N-acetylglucosaminyltransferase activity(GO:0016262) |
0.3 | 0.9 | GO:0004155 | 6,7-dihydropteridine reductase activity(GO:0004155) |
0.3 | 2.2 | GO:0055131 | C3HC4-type RING finger domain binding(GO:0055131) |
0.2 | 1.0 | GO:0015410 | manganese-transporting ATPase activity(GO:0015410) |
0.2 | 1.1 | GO:0035241 | protein-arginine omega-N monomethyltransferase activity(GO:0035241) |
0.2 | 1.0 | GO:0050700 | CARD domain binding(GO:0050700) |
0.2 | 0.8 | GO:0004441 | inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) |
0.2 | 0.8 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
0.2 | 0.8 | GO:0031694 | alpha-2A adrenergic receptor binding(GO:0031694) |
0.2 | 2.4 | GO:0030881 | beta-2-microglobulin binding(GO:0030881) |
0.2 | 0.5 | GO:0042936 | dipeptide transporter activity(GO:0042936) |
0.2 | 0.5 | GO:0052740 | phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740) |
0.2 | 1.1 | GO:0016018 | cyclosporin A binding(GO:0016018) |
0.2 | 0.5 | GO:0005118 | sevenless binding(GO:0005118) |
0.1 | 0.6 | GO:0005093 | Rab GDP-dissociation inhibitor activity(GO:0005093) |
0.1 | 1.2 | GO:0005523 | tropomyosin binding(GO:0005523) |
0.1 | 1.2 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.1 | 0.7 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
0.1 | 0.4 | GO:0008502 | melatonin receptor activity(GO:0008502) |
0.1 | 0.4 | GO:0004492 | methylmalonyl-CoA decarboxylase activity(GO:0004492) |
0.1 | 0.4 | GO:0043120 | tumor necrosis factor binding(GO:0043120) |
0.1 | 0.7 | GO:0051021 | GDP-dissociation inhibitor binding(GO:0051021) |
0.1 | 1.0 | GO:0023026 | MHC class II protein complex binding(GO:0023026) |
0.1 | 0.7 | GO:0008479 | queuine tRNA-ribosyltransferase activity(GO:0008479) |
0.1 | 0.8 | GO:0015091 | ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510) |
0.1 | 0.3 | GO:0047256 | beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256) |
0.1 | 0.3 | GO:0015038 | glutathione disulfide oxidoreductase activity(GO:0015038) |
0.1 | 0.4 | GO:0031727 | CCR2 chemokine receptor binding(GO:0031727) |
0.1 | 0.7 | GO:0005021 | vascular endothelial growth factor-activated receptor activity(GO:0005021) |
0.1 | 0.3 | GO:0015254 | glycerol channel activity(GO:0015254) |
0.1 | 0.7 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
0.1 | 0.3 | GO:0034618 | arginine binding(GO:0034618) |
0.1 | 0.9 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
0.1 | 0.9 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
0.1 | 2.6 | GO:0001671 | ATPase activator activity(GO:0001671) |
0.1 | 0.7 | GO:0036042 | long-chain fatty acyl-CoA binding(GO:0036042) |
0.1 | 0.2 | GO:0001160 | transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160) |
0.1 | 0.6 | GO:0004745 | retinol dehydrogenase activity(GO:0004745) |
0.1 | 0.3 | GO:0004565 | beta-galactosidase activity(GO:0004565) |
0.1 | 0.4 | GO:0046790 | virion binding(GO:0046790) |
0.1 | 0.4 | GO:0061665 | SUMO ligase activity(GO:0061665) |
0.1 | 0.8 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
0.1 | 0.2 | GO:0003956 | NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956) |
0.0 | 0.2 | GO:0070573 | metallodipeptidase activity(GO:0070573) |
0.0 | 2.1 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
0.0 | 0.5 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
0.0 | 0.1 | GO:0003953 | NAD+ nucleosidase activity(GO:0003953) |
0.0 | 3.1 | GO:0003743 | translation initiation factor activity(GO:0003743) |
0.0 | 0.9 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
0.0 | 0.4 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
0.0 | 1.3 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
0.0 | 0.3 | GO:0005041 | low-density lipoprotein receptor activity(GO:0005041) |
0.0 | 0.4 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
0.0 | 1.2 | GO:0004364 | glutathione transferase activity(GO:0004364) |
0.0 | 1.4 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
0.0 | 0.5 | GO:0001530 | lipopolysaccharide binding(GO:0001530) |
0.0 | 0.3 | GO:0001094 | TFIID-class transcription factor binding(GO:0001094) |
0.0 | 0.4 | GO:0008097 | 5S rRNA binding(GO:0008097) |
0.0 | 0.3 | GO:0005243 | gap junction channel activity(GO:0005243) |
0.0 | 0.5 | GO:0003995 | acyl-CoA dehydrogenase activity(GO:0003995) |
0.0 | 0.5 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
0.0 | 0.1 | GO:0034190 | apolipoprotein receptor binding(GO:0034190) |
0.0 | 0.8 | GO:0070717 | poly-purine tract binding(GO:0070717) |
0.0 | 0.1 | GO:1990460 | leptin receptor binding(GO:1990460) |
0.0 | 0.2 | GO:0015187 | glycine transmembrane transporter activity(GO:0015187) |
0.0 | 0.3 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
0.0 | 0.5 | GO:0008432 | JUN kinase binding(GO:0008432) |
0.0 | 0.2 | GO:0042288 | MHC class I protein binding(GO:0042288) |
0.0 | 0.1 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
0.0 | 0.8 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
0.0 | 0.7 | GO:0030291 | protein serine/threonine kinase inhibitor activity(GO:0030291) |
0.0 | 0.0 | GO:0004828 | serine-tRNA ligase activity(GO:0004828) |
0.0 | 0.3 | GO:0003906 | DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906) |
0.0 | 0.7 | GO:0016504 | peptidase activator activity(GO:0016504) |
0.0 | 0.1 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
0.0 | 1.4 | GO:0051213 | dioxygenase activity(GO:0051213) |
0.0 | 0.1 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
0.0 | 0.5 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
0.0 | 0.6 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
0.0 | 0.3 | GO:0097602 | cullin family protein binding(GO:0097602) |
0.0 | 0.0 | GO:0000099 | sulfur amino acid transmembrane transporter activity(GO:0000099) |
0.0 | 0.2 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 4.4 | PID_ERBB_NETWORK_PATHWAY | ErbB receptor signaling network |
0.1 | 0.4 | SA_FAS_SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
0.1 | 4.5 | PID_CASPASE_PATHWAY | Caspase cascade in apoptosis |
0.1 | 0.5 | SA_MMP_CYTOKINE_CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
0.1 | 0.7 | PID_VEGF_VEGFR_PATHWAY | VEGF and VEGFR signaling network |
0.0 | 0.4 | PID_RHODOPSIN_PATHWAY | Visual signal transduction: Rods |
0.0 | 1.1 | PID_IL12_STAT4_PATHWAY | IL12 signaling mediated by STAT4 |
0.0 | 3.6 | PID_CMYB_PATHWAY | C-MYB transcription factor network |
0.0 | 1.8 | PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY | Signaling mediated by p38-alpha and p38-beta |
0.0 | 1.2 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
0.0 | 0.4 | PID_INTEGRIN2_PATHWAY | Beta2 integrin cell surface interactions |
0.0 | 0.7 | PID_IL2_1PATHWAY | IL2-mediated signaling events |
0.0 | 0.8 | PID_ALPHA_SYNUCLEIN_PATHWAY | Alpha-synuclein signaling |
0.0 | 0.5 | PID_TCR_CALCIUM_PATHWAY | Calcium signaling in the CD4+ TCR pathway |
0.0 | 0.6 | PID_ARF6_DOWNSTREAM_PATHWAY | Arf6 downstream pathway |
0.0 | 1.4 | PID_AR_TF_PATHWAY | Regulation of Androgen receptor activity |
0.0 | 0.8 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
0.0 | 0.4 | PID_IL6_7_PATHWAY | IL6-mediated signaling events |
0.0 | 0.2 | PID_NFKAPPAB_CANONICAL_PATHWAY | Canonical NF-kappaB pathway |
0.0 | 0.2 | PID_TCR_RAS_PATHWAY | Ras signaling in the CD4+ TCR pathway |
0.0 | 0.8 | PID_ANGIOPOIETIN_RECEPTOR_PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
0.0 | 0.7 | PID_HNF3B_PATHWAY | FOXA2 and FOXA3 transcription factor networks |
0.0 | 0.3 | PID_PRL_SIGNALING_EVENTS_PATHWAY | Signaling events mediated by PRL |
0.0 | 0.2 | ST_INTERLEUKIN_4_PATHWAY | Interleukin 4 (IL-4) Pathway |
0.0 | 0.4 | PID_FAS_PATHWAY | FAS (CD95) signaling pathway |
0.0 | 0.2 | PID_IL2_PI3K_PATHWAY | IL2 signaling events mediated by PI3K |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 1.8 | REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
0.2 | 4.4 | REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
0.1 | 2.6 | REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
0.1 | 2.4 | REACTOME_DEADENYLATION_OF_MRNA | Genes involved in Deadenylation of mRNA |
0.1 | 0.4 | REACTOME_OLFACTORY_SIGNALING_PATHWAY | Genes involved in Olfactory Signaling Pathway |
0.1 | 0.6 | REACTOME_ER_PHAGOSOME_PATHWAY | Genes involved in ER-Phagosome pathway |
0.1 | 1.6 | REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT | Genes involved in ABC-family proteins mediated transport |
0.0 | 0.4 | REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR | Genes involved in Trafficking and processing of endosomal TLR |
0.0 | 0.8 | REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
0.0 | 1.2 | REACTOME_STRIATED_MUSCLE_CONTRACTION | Genes involved in Striated Muscle Contraction |
0.0 | 0.3 | REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
0.0 | 0.8 | REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
0.0 | 0.8 | REACTOME_TIE2_SIGNALING | Genes involved in Tie2 Signaling |
0.0 | 0.7 | REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS | Genes involved in Activation of BH3-only proteins |
0.0 | 5.6 | REACTOME_SIGNALING_BY_RHO_GTPASES | Genes involved in Signaling by Rho GTPases |
0.0 | 0.8 | REACTOME_KINESINS | Genes involved in Kinesins |
0.0 | 0.4 | REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
0.0 | 1.9 | REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
0.0 | 0.9 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | Genes involved in Ion transport by P-type ATPases |
0.0 | 0.7 | REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING | Genes involved in Growth hormone receptor signaling |
0.0 | 0.6 | REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
0.0 | 0.4 | REACTOME_INSULIN_RECEPTOR_RECYCLING | Genes involved in Insulin receptor recycling |
0.0 | 0.5 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
0.0 | 0.9 | REACTOME_RNA_POL_I_TRANSCRIPTION | Genes involved in RNA Polymerase I Transcription |
0.0 | 0.1 | REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
0.0 | 0.4 | REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
0.0 | 1.0 | REACTOME_MEIOTIC_SYNAPSIS | Genes involved in Meiotic Synapsis |
0.0 | 0.8 | REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 | Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0) |
0.0 | 0.3 | REACTOME_GLUTATHIONE_CONJUGATION | Genes involved in Glutathione conjugation |