Motif ID: Elf3

Z-value: 1.027


Transcription factors associated with Elf3:

Gene SymbolEntrez IDGene Name
Elf3 ENSMUSG00000003051.7 Elf3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Elf3mm10_v2_chr1_-_135258449_1352584720.443.8e-03Click!


Activity profile for motif Elf3.

activity profile for motif Elf3


Sorted Z-values histogram for motif Elf3

Sorted Z-values for motif Elf3



Network of associatons between targets according to the STRING database.



First level regulatory network of Elf3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_55419898 6.022 ENSMUST00000108858.1
ENSMUST00000141530.1
Sparc

secreted acidic cysteine rich glycoprotein

chr11_+_78324200 5.100 ENSMUST00000102478.3
Aldoc
aldolase C, fructose-bisphosphate
chr14_-_70207637 4.844 ENSMUST00000022682.5
Sorbs3
sorbin and SH3 domain containing 3
chr15_+_79516396 4.239 ENSMUST00000010974.7
Kdelr3
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr11_+_115163333 3.819 ENSMUST00000021077.3
Slc9a3r1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr4_-_14621805 3.446 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr6_+_15720654 3.416 ENSMUST00000101663.3
Mdfic
MyoD family inhibitor domain containing
chr14_-_54577578 3.398 ENSMUST00000054487.8
Ajuba
ajuba LIM protein
chr2_+_164562579 3.304 ENSMUST00000017867.3
ENSMUST00000109344.2
ENSMUST00000109345.2
Wfdc2


WAP four-disulfide core domain 2


chr17_+_35049966 3.230 ENSMUST00000007257.9
Clic1
chloride intracellular channel 1
chr19_-_50678642 2.853 ENSMUST00000072685.6
ENSMUST00000164039.2
Sorcs1

VPS10 domain receptor protein SORCS 1

chr11_+_61653259 2.846 ENSMUST00000004959.2
Grap
GRB2-related adaptor protein
chr12_-_65172560 2.725 ENSMUST00000052201.8
Mis18bp1
MIS18 binding protein 1
chr6_+_15721087 2.708 ENSMUST00000120512.1
Mdfic
MyoD family inhibitor domain containing
chr19_-_50678485 2.703 ENSMUST00000111756.3
Sorcs1
VPS10 domain receptor protein SORCS 1
chr11_-_48816936 2.640 ENSMUST00000140800.1
Trim41
tripartite motif-containing 41
chr10_-_83648713 2.524 ENSMUST00000020500.7
Appl2
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr1_+_51987139 2.473 ENSMUST00000168302.1
Stat4
signal transducer and activator of transcription 4
chr19_+_16435616 2.360 ENSMUST00000025602.2
Gna14
guanine nucleotide binding protein, alpha 14
chr5_+_110330697 2.321 ENSMUST00000112481.1
Pole
polymerase (DNA directed), epsilon
chr18_+_56432116 2.175 ENSMUST00000070166.5
Gramd3
GRAM domain containing 3
chr11_+_53770014 2.172 ENSMUST00000108920.2
ENSMUST00000140866.1
ENSMUST00000108922.1
Irf1


interferon regulatory factor 1


chr4_-_106464167 2.042 ENSMUST00000049507.5
Pcsk9
proprotein convertase subtilisin/kexin type 9
chr11_+_53770458 2.029 ENSMUST00000138913.1
ENSMUST00000123376.1
ENSMUST00000019043.6
ENSMUST00000133291.1
Irf1



interferon regulatory factor 1



chr2_+_20737306 2.005 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4

enhancer trap locus 4

chr7_+_101378183 1.983 ENSMUST00000084895.5
Arap1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr7_-_102250086 1.963 ENSMUST00000106923.1
ENSMUST00000098230.4
Rhog

ras homolog gene family, member G

chr1_+_84839833 1.821 ENSMUST00000097672.3
Fbxo36
F-box protein 36
chr9_-_54647199 1.735 ENSMUST00000128163.1
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chrX_+_169685191 1.727 ENSMUST00000112104.1
ENSMUST00000112107.1
Mid1

midline 1

chr16_+_62854299 1.656 ENSMUST00000023629.8
Pros1
protein S (alpha)
chr4_-_14621494 1.654 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chr4_-_14621669 1.639 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr14_+_25983005 1.637 ENSMUST00000049793.8
Duxbl1
double homeobox B-like 1
chr1_-_13589717 1.619 ENSMUST00000027068.4
Tram1
translocating chain-associating membrane protein 1
chr1_+_58795371 1.568 ENSMUST00000027189.8
Casp8
caspase 8
chr1_+_58802492 1.531 ENSMUST00000165549.1
Casp8
caspase 8
chr4_-_118489755 1.513 ENSMUST00000184261.1
Tie1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr14_-_20496780 1.500 ENSMUST00000022353.3
Mss51
MSS51 mitochondrial translational activator
chr2_+_31572651 1.495 ENSMUST00000113482.1
Fubp3
far upstream element (FUSE) binding protein 3
chr6_+_29694204 1.478 ENSMUST00000046750.7
ENSMUST00000115250.3
Tspan33

tetraspanin 33

chr2_+_31470207 1.461 ENSMUST00000102840.4
Ass1
argininosuccinate synthetase 1
chr1_+_16688405 1.439 ENSMUST00000026881.4
Ly96
lymphocyte antigen 96
chr19_+_5740885 1.429 ENSMUST00000081496.5
Ltbp3
latent transforming growth factor beta binding protein 3
chr14_-_57890242 1.398 ENSMUST00000089473.3
Zdhhc20
zinc finger, DHHC domain containing 20
chr6_-_146502141 1.391 ENSMUST00000079573.6
ENSMUST00000139732.1
Itpr2

inositol 1,4,5-triphosphate receptor 2

chr15_-_36608959 1.368 ENSMUST00000001809.8
Pabpc1
poly(A) binding protein, cytoplasmic 1
chr6_+_71272019 1.360 ENSMUST00000168700.1
Krcc1
lysine-rich coiled-coil 1
chr8_-_71395794 1.337 ENSMUST00000049184.7
Ushbp1
Usher syndrome 1C binding protein 1
chr3_-_84582476 1.331 ENSMUST00000107687.2
ENSMUST00000098990.3
Arfip1

ADP-ribosylation factor interacting protein 1

chr3_-_89418287 1.324 ENSMUST00000029679.3
Cks1b
CDC28 protein kinase 1b
chr11_-_70654598 1.312 ENSMUST00000108549.1
Pfn1
profilin 1
chr3_+_146499828 1.312 ENSMUST00000090031.5
Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr11_+_111066154 1.310 ENSMUST00000042970.2
Kcnj2
potassium inwardly-rectifying channel, subfamily J, member 2
chr17_+_86963279 1.306 ENSMUST00000139344.1
Rhoq
ras homolog gene family, member Q
chr7_-_116198487 1.300 ENSMUST00000181981.1
Plekha7
pleckstrin homology domain containing, family A member 7
chr3_-_51396528 1.286 ENSMUST00000038154.5
Mgarp
mitochondria localized glutamic acid rich protein
chr3_+_146499850 1.278 ENSMUST00000118280.1
Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr2_+_31670714 1.277 ENSMUST00000038474.7
ENSMUST00000137156.1
Exosc2

exosome component 2

chr17_+_86753900 1.263 ENSMUST00000024954.9
Epas1
endothelial PAS domain protein 1
chr8_+_104340594 1.251 ENSMUST00000034343.4
Cmtm3
CKLF-like MARVEL transmembrane domain containing 3
chr11_-_100850724 1.241 ENSMUST00000004143.2
Stat5b
signal transducer and activator of transcription 5B
chr11_-_48817332 1.226 ENSMUST00000047145.7
Trim41
tripartite motif-containing 41
chr3_-_51396716 1.199 ENSMUST00000141156.1
Mgarp
mitochondria localized glutamic acid rich protein
chr6_-_48708206 1.190 ENSMUST00000119315.1
ENSMUST00000053661.4
Gimap6

GTPase, IMAP family member 6

chr3_+_90603767 1.149 ENSMUST00000001046.5
ENSMUST00000107330.1
S100a4

S100 calcium binding protein A4

chr11_-_70654624 1.142 ENSMUST00000018437.2
Pfn1
profilin 1
chr2_+_126215100 1.114 ENSMUST00000164042.2
Gm17555
predicted gene, 17555
chr4_+_108847827 1.085 ENSMUST00000102738.2
Kti12
KTI12 homolog, chromatin associated (S. cerevisiae)
chr13_-_103920508 1.083 ENSMUST00000053927.5
ENSMUST00000091269.4
ENSMUST00000022222.5
Erbb2ip


Erbb2 interacting protein


chr13_-_103920295 1.052 ENSMUST00000169083.1
Erbb2ip
Erbb2 interacting protein
chr12_-_80260356 1.022 ENSMUST00000021554.8
Actn1
actinin, alpha 1
chr15_+_55557399 1.015 ENSMUST00000022998.7
Mtbp
Mdm2, transformed 3T3 cell double minute p53 binding protein
chr1_+_15805639 1.001 ENSMUST00000027057.6
Terf1
telomeric repeat binding factor 1
chr3_-_51396502 0.984 ENSMUST00000108046.1
Mgarp
mitochondria localized glutamic acid rich protein
chr2_-_72980402 0.977 ENSMUST00000066003.6
ENSMUST00000102689.3
Sp3

trans-acting transcription factor 3

chr13_+_13437602 0.950 ENSMUST00000005532.7
Nid1
nidogen 1
chr7_+_119793987 0.947 ENSMUST00000033218.8
ENSMUST00000106520.1
2610020H08Rik

RIKEN cDNA 2610020H08 gene

chr1_+_136467958 0.945 ENSMUST00000047817.6
Kif14
kinesin family member 14
chr7_-_3677509 0.943 ENSMUST00000038743.8
Tmc4
transmembrane channel-like gene family 4
chr7_-_80232479 0.929 ENSMUST00000123279.1
Cib1
calcium and integrin binding 1 (calmyrin)
chr10_+_94198955 0.926 ENSMUST00000020209.9
ENSMUST00000179990.1
Ndufa12

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12

chr16_-_44016387 0.919 ENSMUST00000036174.3
Gramd1c
GRAM domain containing 1C
chr7_+_119794102 0.913 ENSMUST00000084644.2
2610020H08Rik
RIKEN cDNA 2610020H08 gene
chr5_+_115845229 0.901 ENSMUST00000137952.1
ENSMUST00000148245.1
Cit

citron

chr14_+_31208309 0.884 ENSMUST00000169169.1
Tnnc1
troponin C, cardiac/slow skeletal
chr10_-_89443888 0.858 ENSMUST00000099374.2
ENSMUST00000105298.1
Gas2l3

growth arrest-specific 2 like 3

chr15_-_83432819 0.855 ENSMUST00000165095.1
Pacsin2
protein kinase C and casein kinase substrate in neurons 2
chr8_+_72646679 0.852 ENSMUST00000161386.1
ENSMUST00000093427.4
Nwd1

NACHT and WD repeat domain containing 1

chr7_-_81345189 0.845 ENSMUST00000080813.4
Rps17
ribosomal protein S17
chr3_-_146499721 0.837 ENSMUST00000029839.4
Spata1
spermatogenesis associated 1
chr8_+_72646728 0.835 ENSMUST00000161254.1
Nwd1
NACHT and WD repeat domain containing 1
chr10_+_79988584 0.833 ENSMUST00000004784.4
ENSMUST00000105374.1
Cnn2

calponin 2

chr7_-_101933780 0.814 ENSMUST00000106964.1
ENSMUST00000078448.3
Lrrc51

leucine rich repeat containing 51

chr10_-_23787195 0.814 ENSMUST00000073926.6
Rps12
ribosomal protein S12
chr9_-_120068263 0.809 ENSMUST00000064165.3
ENSMUST00000177637.1
Cx3cr1

chemokine (C-X3-C) receptor 1

chr7_-_128298081 0.800 ENSMUST00000033044.9
BC017158
cDNA sequence BC017158
chr14_+_34673888 0.799 ENSMUST00000048263.7
Wapal
wings apart-like homolog (Drosophila)
chr2_+_105904629 0.792 ENSMUST00000037499.5
Immp1l
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr7_-_101933815 0.790 ENSMUST00000106963.1
ENSMUST00000106966.1
Lrrc51

leucine rich repeat containing 51

chr5_-_105343929 0.776 ENSMUST00000183149.1
Gbp11
guanylate binding protein 11
chr19_+_46305682 0.760 ENSMUST00000111881.2
Nfkb2
nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
chr10_+_80249106 0.759 ENSMUST00000105364.1
Ndufs7
NADH dehydrogenase (ubiquinone) Fe-S protein 7
chr1_-_155527083 0.745 ENSMUST00000097531.2
Gm5532
predicted gene 5532
chr16_-_24393588 0.745 ENSMUST00000181640.1
1110054M08Rik
RIKEN cDNA 1110054M08 gene
chr1_+_36307745 0.738 ENSMUST00000142319.1
ENSMUST00000097778.2
ENSMUST00000115031.1
ENSMUST00000115032.1
ENSMUST00000137906.1
ENSMUST00000115029.1
Arid5a





AT rich interactive domain 5A (MRF1-like)





chr15_-_37458523 0.734 ENSMUST00000116445.2
Ncald
neurocalcin delta
chr17_-_47834682 0.722 ENSMUST00000066368.6
Mdfi
MyoD family inhibitor
chr10_+_80249441 0.713 ENSMUST00000020361.6
Ndufs7
NADH dehydrogenase (ubiquinone) Fe-S protein 7
chr6_-_146502099 0.708 ENSMUST00000053273.8
Itpr2
inositol 1,4,5-triphosphate receptor 2
chrX_-_8090442 0.708 ENSMUST00000033505.6
Was
Wiskott-Aldrich syndrome homolog (human)
chr9_+_44407629 0.702 ENSMUST00000080300.7
Rps25
ribosomal protein S25
chr14_+_34375504 0.695 ENSMUST00000111908.1
Mmrn2
multimerin 2
chr11_+_117232254 0.693 ENSMUST00000106354.2
Sept9
septin 9
chr4_-_156255327 0.691 ENSMUST00000179919.1
Samd11
sterile alpha motif domain containing 11
chr10_+_83543941 0.687 ENSMUST00000038388.5
A230046K03Rik
RIKEN cDNA A230046K03 gene
chr14_-_54253907 0.673 ENSMUST00000128231.1
Dad1
defender against cell death 1
chr9_-_20898592 0.672 ENSMUST00000004206.8
Eif3g
eukaryotic translation initiation factor 3, subunit G
chr2_-_73580288 0.659 ENSMUST00000028515.3
Chrna1
cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
chr7_-_125491586 0.654 ENSMUST00000033006.7
Nsmce1
non-SMC element 1 homolog (S. cerevisiae)
chr16_-_4559720 0.654 ENSMUST00000005862.7
Tfap4
transcription factor AP4
chr13_-_41847482 0.647 ENSMUST00000072012.3
Adtrp
androgen dependent TFPI regulating protein
chr18_-_3281036 0.642 ENSMUST00000049942.6
ENSMUST00000139537.1
ENSMUST00000124747.1
Crem


cAMP responsive element modulator


chr6_-_8259098 0.625 ENSMUST00000012627.4
Rpa3
replication protein A3
chr1_-_4496400 0.602 ENSMUST00000027035.3
Sox17
SRY-box containing gene 17
chr4_-_136053343 0.598 ENSMUST00000102536.4
Rpl11
ribosomal protein L11
chr10_-_83648631 0.586 ENSMUST00000146876.2
ENSMUST00000176294.1
Appl2

adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2

chr11_+_120598421 0.572 ENSMUST00000026128.3
Anapc11
anaphase promoting complex subunit 11
chr14_-_11356726 0.568 ENSMUST00000181173.1
Gm3839
predicted pseudogene 3839
chr14_-_8309770 0.566 ENSMUST00000121887.1
ENSMUST00000036070.8
ENSMUST00000137133.1
Fam107a


family with sequence similarity 107, member A


chr7_-_44375006 0.560 ENSMUST00000107933.1
1700008O03Rik
RIKEN cDNA 1700008O03 gene
chr3_+_145576196 0.556 ENSMUST00000098534.4
Znhit6
zinc finger, HIT type 6
chr7_+_101896340 0.549 ENSMUST00000035395.7
ENSMUST00000106973.1
ENSMUST00000144207.1
Anapc15


anaphase prompoting complex C subunit 15


chr10_-_62231208 0.534 ENSMUST00000047883.9
Tspan15
tetraspanin 15
chr7_+_102065713 0.532 ENSMUST00000094129.2
ENSMUST00000094130.2
ENSMUST00000084843.3
Trpc2


transient receptor potential cation channel, subfamily C, member 2


chr4_-_53159885 0.528 ENSMUST00000030010.3
Abca1
ATP-binding cassette, sub-family A (ABC1), member 1
chr6_+_122308684 0.519 ENSMUST00000007602.8
ENSMUST00000112610.1
M6pr

mannose-6-phosphate receptor, cation dependent

chr7_-_125491397 0.514 ENSMUST00000138616.1
Nsmce1
non-SMC element 1 homolog (S. cerevisiae)
chr3_+_89418443 0.514 ENSMUST00000039110.5
ENSMUST00000125036.1
ENSMUST00000154791.1
ENSMUST00000128238.1
ENSMUST00000107417.2
Shc1




src homology 2 domain-containing transforming protein C1




chr7_+_30563838 0.511 ENSMUST00000163330.1
U2af1l4
U2 small nuclear RNA auxiliary factor 1-like 4
chr14_-_31830402 0.510 ENSMUST00000014640.7
Ankrd28
ankyrin repeat domain 28
chr11_+_51261719 0.504 ENSMUST00000130641.1
Clk4
CDC like kinase 4
chr9_+_6168601 0.497 ENSMUST00000168039.1
Pdgfd
platelet-derived growth factor, D polypeptide
chr1_+_72711259 0.494 ENSMUST00000059980.9
Rpl37a
ribosomal protein L37a
chr2_-_105904484 0.491 ENSMUST00000122965.1
Elp4
elongation protein 4 homolog (S. cerevisiae)
chr7_+_105640448 0.488 ENSMUST00000058333.3
Timm10b
translocase of inner mitochondrial membrane 10B
chr6_-_24527546 0.487 ENSMUST00000118558.1
Ndufa5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr10_-_30655859 0.483 ENSMUST00000092610.4
Ncoa7
nuclear receptor coactivator 7
chr4_+_150237694 0.474 ENSMUST00000141931.1
Eno1
enolase 1, alpha non-neuron
chr17_-_25880236 0.474 ENSMUST00000176696.1
ENSMUST00000095487.5
Wfikkn1

WAP, FS, Ig, KU, and NTR-containing protein 1

chr9_+_35559460 0.473 ENSMUST00000034615.3
ENSMUST00000121246.1
Pus3

pseudouridine synthase 3

chr10_+_76449074 0.472 ENSMUST00000092406.5
2610028H24Rik
RIKEN cDNA 2610028H24 gene
chr13_-_55100248 0.471 ENSMUST00000026997.5
ENSMUST00000127195.1
ENSMUST00000099496.3
Uimc1


ubiquitin interaction motif containing 1


chr4_+_44756553 0.470 ENSMUST00000107824.2
Zcchc7
zinc finger, CCHC domain containing 7
chr12_-_69357120 0.463 ENSMUST00000021368.8
Nemf
nuclear export mediator factor
chr16_+_41532851 0.461 ENSMUST00000078873.4
Lsamp
limbic system-associated membrane protein
chr10_+_93540626 0.458 ENSMUST00000092215.5
Ccdc38
coiled-coil domain containing 38
chr8_-_83442648 0.455 ENSMUST00000167525.1
Scoc
short coiled-coil protein
chr7_+_27486910 0.453 ENSMUST00000008528.7
Sertad1
SERTA domain containing 1
chr5_+_43672289 0.453 ENSMUST00000156034.1
Cc2d2a
coiled-coil and C2 domain containing 2A
chr19_+_6363671 0.447 ENSMUST00000131252.1
Sf1
splicing factor 1
chr8_+_3493135 0.435 ENSMUST00000061508.7
Zfp358
zinc finger protein 358
chr2_-_148045891 0.433 ENSMUST00000109964.1
Foxa2
forkhead box A2
chr6_-_4086914 0.426 ENSMUST00000049166.4
Bet1
blocked early in transport 1 homolog (S. cerevisiae)
chr3_+_96645579 0.403 ENSMUST00000119365.1
ENSMUST00000029744.5
Itga10

integrin, alpha 10

chr7_+_105640522 0.398 ENSMUST00000106785.1
ENSMUST00000106786.1
ENSMUST00000106780.1
ENSMUST00000106784.1
Timm10b



translocase of inner mitochondrial membrane 10B



chr13_-_41847626 0.398 ENSMUST00000121404.1
Adtrp
androgen dependent TFPI regulating protein
chr7_-_15946070 0.398 ENSMUST00000044158.8
Gltscr2
glioma tumor suppressor candidate region gene 2
chr5_-_34637203 0.393 ENSMUST00000114331.3
Mfsd10
major facilitator superfamily domain containing 10
chr19_+_8850785 0.389 ENSMUST00000096257.2
Lrrn4cl
LRRN4 C-terminal like
chr4_+_53826014 0.385 ENSMUST00000030127.6
Tmem38b
transmembrane protein 38B
chr8_-_67515606 0.380 ENSMUST00000032981.5
Gm9755
predicted pseudogene 9755
chr7_+_102065485 0.379 ENSMUST00000106950.1
ENSMUST00000146450.1
Trpc2

transient receptor potential cation channel, subfamily C, member 2

chr4_-_40722307 0.377 ENSMUST00000181475.1
Gm6297
predicted gene 6297
chr1_-_136230289 0.376 ENSMUST00000150163.1
ENSMUST00000144464.1
5730559C18Rik

RIKEN cDNA 5730559C18 gene

chr19_+_6363719 0.370 ENSMUST00000113489.1
ENSMUST00000113488.1
Sf1

splicing factor 1

chr6_-_86793522 0.366 ENSMUST00000001187.8
Anxa4
annexin A4
chr2_+_26581050 0.357 ENSMUST00000166920.2
Egfl7
EGF-like domain 7
chr2_-_30474199 0.352 ENSMUST00000065134.2
Ier5l
immediate early response 5-like
chr6_-_24515036 0.352 ENSMUST00000052277.4
Iqub
IQ motif and ubiquitin domain containing
chr2_+_165055625 0.348 ENSMUST00000017799.5
ENSMUST00000073707.2
Cd40

CD40 antigen

chr2_+_29827342 0.332 ENSMUST00000091142.3
Urm1
ubiquitin related modifier 1 homolog (S. cerevisiae)
chr5_-_34637107 0.327 ENSMUST00000124668.1
ENSMUST00000001109.4
ENSMUST00000155577.1
ENSMUST00000114329.1
Mfsd10



major facilitator superfamily domain containing 10



chr1_+_138963709 0.312 ENSMUST00000168527.1
Dennd1b
DENN/MADD domain containing 1B
chrX_+_68821093 0.310 ENSMUST00000096420.2
Gm14698
predicted gene 14698
chrX_-_163761323 0.310 ENSMUST00000059320.2
Rnf138rt1
ring finger protein 138, retrogene 1
chr7_-_80901220 0.308 ENSMUST00000146402.1
ENSMUST00000026816.8
Wdr73

WD repeat domain 73

chrX_+_142226765 0.301 ENSMUST00000112916.2
Nxt2
nuclear transport factor 2-like export factor 2
chr3_-_116614587 0.291 ENSMUST00000041524.4
Trmt13
tRNA methyltransferase 13
chr5_+_33983437 0.288 ENSMUST00000114384.1
ENSMUST00000094869.5
ENSMUST00000114383.1
Gm1673


predicted gene 1673


chr6_-_124741374 0.286 ENSMUST00000004389.5
Grcc10
gene rich cluster, C10 gene
chr3_-_146839365 0.283 ENSMUST00000084614.3
Gm10288
predicted gene 10288
chr11_-_97996171 0.275 ENSMUST00000042971.9
Arl5c
ADP-ribosylation factor-like 5C
chr4_-_156228540 0.274 ENSMUST00000105571.2
Plekhn1
pleckstrin homology domain containing, family N member 1
chr3_+_90051630 0.273 ENSMUST00000159064.1
4933434E20Rik
RIKEN cDNA 4933434E20 gene
chr18_+_24470844 0.272 ENSMUST00000097646.3
2700062C07Rik
RIKEN cDNA 2700062C07 gene
chr16_+_19760232 0.269 ENSMUST00000079780.3
ENSMUST00000164397.1
B3gnt5

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5

chr11_-_17008647 0.261 ENSMUST00000102881.3
Plek
pleckstrin
chr9_-_116175318 0.255 ENSMUST00000061101.4
ENSMUST00000035014.6
Tgfbr2

transforming growth factor, beta receptor II

chr19_-_41933276 0.254 ENSMUST00000075280.4
ENSMUST00000112123.2
Exosc1

exosome component 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) negative regulation of regulatory T cell differentiation(GO:0045590) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
1.3 3.8 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
1.0 6.7 GO:0019532 oxalate transport(GO:0019532)
0.9 3.5 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.8 2.3 GO:0045004 DNA replication proofreading(GO:0045004)
0.6 1.3 GO:1903181 regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181)
0.6 4.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.6 2.4 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.5 2.0 GO:0001920 negative regulation of receptor recycling(GO:0001920) negative regulation of low-density lipoprotein particle clearance(GO:0010989) positive regulation of low-density lipoprotein particle receptor catabolic process(GO:0032805)
0.5 5.1 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.5 3.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.5 1.4 GO:1902460 transforming growth factor beta activation(GO:0036363) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.4 2.6 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.4 1.2 GO:0046544 regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819) development of secondary male sexual characteristics(GO:0046544)
0.4 1.5 GO:0010046 arginine biosynthetic process(GO:0006526) response to mycotoxin(GO:0010046)
0.4 2.5 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.3 1.3 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.3 0.9 GO:2000256 positive regulation of male germ cell proliferation(GO:2000256)
0.3 2.1 GO:0071361 cellular response to ethanol(GO:0071361)
0.3 1.4 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.3 3.1 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.3 1.4 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.3 6.5 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.3 0.8 GO:0060913 stem cell fate specification(GO:0048866) cardiac cell fate determination(GO:0060913) regulation of cardiac cell fate specification(GO:2000043)
0.3 0.5 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.3 1.3 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.3 1.0 GO:0097694 establishment of RNA localization to telomere(GO:0097694)
0.2 0.9 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.2 1.6 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
0.2 0.9 GO:0002086 diaphragm contraction(GO:0002086)
0.2 1.3 GO:0045218 zonula adherens maintenance(GO:0045218)
0.2 0.9 GO:0070836 caveola assembly(GO:0070836)
0.2 1.3 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.2 0.6 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.2 1.7 GO:0035372 protein localization to microtubule(GO:0035372)
0.2 0.7 GO:2000318 positive regulation of T-helper 17 type immune response(GO:2000318)
0.2 1.7 GO:0042730 fibrinolysis(GO:0042730)
0.2 0.9 GO:0002121 inter-male aggressive behavior(GO:0002121) response to pheromone(GO:0019236)
0.2 0.5 GO:0035696 monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
0.2 6.0 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.2 1.0 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.2 0.8 GO:0002677 negative regulation of chronic inflammatory response(GO:0002677)
0.1 2.1 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.1 0.4 GO:0045014 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594)
0.1 0.7 GO:0042891 antibiotic transport(GO:0042891)
0.1 0.7 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.1 1.0 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 0.7 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.1 0.7 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.1 0.3 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.1 0.5 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.1 0.8 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.5 GO:1990839 response to endothelin(GO:1990839)
0.1 0.6 GO:0048254 snoRNA localization(GO:0048254)
0.1 0.6 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.1 2.7 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.1 0.5 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 3.8 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.1 0.5 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 3.2 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 1.0 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.1 GO:2001187 positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.1 0.3 GO:0010920 negative regulation of inositol phosphate biosynthetic process(GO:0010920)
0.1 0.2 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743) alveolar secondary septum development(GO:0061144)
0.1 1.2 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.1 1.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.7 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1 0.4 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.1 0.8 GO:0030238 male sex determination(GO:0030238)
0.1 0.5 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.1 0.2 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.1 0.3 GO:0034227 tRNA thio-modification(GO:0034227)
0.1 0.8 GO:0002467 germinal center formation(GO:0002467)
0.1 0.9 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.1 0.5 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 1.5 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 0.7 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.5 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.2 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 0.4 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.0 0.8 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 1.7 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.7 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 1.2 GO:0006301 postreplication repair(GO:0006301)
0.0 0.3 GO:0035743 CD4-positive, alpha-beta T cell cytokine production(GO:0035743) T-helper 2 cell cytokine production(GO:0035745)
0.0 0.2 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0 0.3 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 1.8 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.0 0.4 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.2 GO:0051461 regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.6 GO:0006298 mismatch repair(GO:0006298)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.7 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 1.3 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 1.6 GO:0045580 regulation of T cell differentiation(GO:0045580)
0.0 0.5 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 2.0 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.7 GO:0042775 mitochondrial ATP synthesis coupled electron transport(GO:0042775)
0.0 0.6 GO:0051591 response to cAMP(GO:0051591)
0.0 0.4 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.1 GO:0034143 regulation of toll-like receptor 4 signaling pathway(GO:0034143)
0.0 0.2 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.7 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 6.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
1.0 3.1 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.9 2.6 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.7 2.0 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.5 2.3 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.3 3.8 GO:0032426 stereocilium tip(GO:0032426)
0.3 0.8 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.3 1.0 GO:0032127 dense core granule membrane(GO:0032127)
0.2 1.4 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 2.0 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 0.9 GO:1990584 cardiac Troponin complex(GO:1990584)
0.2 2.7 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.2 0.9 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.2 1.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 1.0 GO:0070187 telosome(GO:0070187)
0.1 1.5 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 3.1 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 1.3 GO:0005915 zonula adherens(GO:0005915)
0.1 3.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 1.5 GO:0070852 cell body fiber(GO:0070852)
0.1 2.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.8 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.5 GO:0070531 BRCA1-A complex(GO:0070531)
0.1 3.2 GO:0034707 chloride channel complex(GO:0034707)
0.1 1.7 GO:0005682 U5 snRNP(GO:0005682)
0.1 0.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 3.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 2.9 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 0.2 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 0.5 GO:0089701 U2AF(GO:0089701)
0.1 0.9 GO:0032433 filopodium tip(GO:0032433)
0.1 0.5 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.6 GO:0070761 pre-snoRNP complex(GO:0070761)
0.1 1.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.7 GO:0031105 septin complex(GO:0031105)
0.0 0.1 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 1.0 GO:0005605 basal lamina(GO:0005605)
0.0 2.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 2.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 3.9 GO:0072562 blood microparticle(GO:0072562)
0.0 0.7 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.6 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 1.3 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.9 GO:0051233 spindle midzone(GO:0051233)
0.0 0.8 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.5 GO:0036038 MKS complex(GO:0036038)
0.0 0.9 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.4 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 6.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.1 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 1.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.3 GO:0043196 varicosity(GO:0043196)
0.0 2.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.3 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.2 GO:0051286 cell tip(GO:0051286)
0.0 0.7 GO:0031526 brush border membrane(GO:0031526)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.5 GO:0030904 retromer complex(GO:0030904)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 1.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.0 GO:0036125 mitochondrial fatty acid beta-oxidation multienzyme complex(GO:0016507) fatty acid beta-oxidation multienzyme complex(GO:0036125)
0.0 0.8 GO:0005901 caveola(GO:0005901)
0.0 0.7 GO:0005604 basement membrane(GO:0005604)
0.0 1.0 GO:0005884 actin filament(GO:0005884)
0.0 0.1 GO:0097225 sperm midpiece(GO:0097225)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.2 GO:0046923 ER retention sequence binding(GO:0046923)
0.8 5.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.8 3.1 GO:0035877 death effector domain binding(GO:0035877)
0.8 2.3 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.7 2.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.7 2.0 GO:0034190 very-low-density lipoprotein particle binding(GO:0034189) apolipoprotein receptor binding(GO:0034190)
0.7 3.3 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.6 6.7 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.5 1.4 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.3 5.6 GO:0030957 Tat protein binding(GO:0030957)
0.3 5.8 GO:0017166 vinculin binding(GO:0017166)
0.3 1.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.3 3.8 GO:0017081 chloride channel regulator activity(GO:0017081)
0.3 0.6 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.3 2.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.3 3.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.2 0.8 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.2 1.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.2 0.9 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.2 0.9 GO:0031014 troponin T binding(GO:0031014)
0.2 0.5 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.2 1.0 GO:0071532 ankyrin repeat binding(GO:0071532)
0.2 1.3 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.2 0.8 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.2 1.7 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.7 GO:0042895 antibiotic transporter activity(GO:0042895)
0.1 6.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 1.0 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.4 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 1.3 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.5 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 1.5 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.4 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 0.7 GO:0042731 PH domain binding(GO:0042731)
0.1 1.8 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 1.5 GO:0048038 quinone binding(GO:0048038)
0.1 1.3 GO:0005522 profilin binding(GO:0005522)
0.1 1.3 GO:0050897 cobalt ion binding(GO:0050897)
0.1 2.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 0.6 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1 0.9 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1 0.5 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 0.7 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 1.7 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 0.6 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.1 1.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.2 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 1.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 3.2 GO:0005254 chloride channel activity(GO:0005254)
0.1 0.5 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.9 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.6 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 5.8 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 1.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 1.1 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.5 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.5 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.5 GO:0005537 mannose binding(GO:0005537)
0.0 0.6 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.2 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.4 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.3 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 1.0 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 7.2 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.4 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.1 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.3 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 1.3 GO:0005125 cytokine activity(GO:0005125)
0.0 1.7 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.0 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.0 2.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.6 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.3 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.1 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.2 6.7 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.2 2.1 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.1 2.1 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 0.7 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.1 1.3 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.1 9.1 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 3.8 PID_TXA2PATHWAY Thromboxane A2 receptor signaling
0.1 2.2 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.1 6.1 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 1.0 PID_IL5_PATHWAY IL5-mediated signaling events
0.1 1.3 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.1 2.5 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 0.3 PID_CD40_PATHWAY CD40/CD40L signaling
0.0 0.4 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.0 1.3 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 0.5 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.0 0.8 ST_GAQ_PATHWAY G alpha q Pathway
0.0 1.3 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.4 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 2.0 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 0.6 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.5 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.1 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.0 0.5 PID_ATM_PATHWAY ATM pathway
0.0 0.6 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 0.7 PID_TCR_PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.3 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 1.1 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.3 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.1 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.3 1.7 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.3 2.4 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2 3.1 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.2 4.2 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.2 1.0 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.2 2.9 REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.2 1.5 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 1.4 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 5.6 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 4.8 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 9.1 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 1.2 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.1 3.9 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 4.8 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 0.7 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 0.9 REACTOME_MUSCLE_CONTRACTION Genes involved in Muscle contraction
0.1 0.8 REACTOME_TRAF6_MEDIATED_NFKB_ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.1 1.3 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 4.4 REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.1 1.5 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 0.7 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 2.7 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 4.6 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 2.6 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 0.8 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.7 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES Genes involved in Generation of second messenger molecules
0.0 1.3 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.6 REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.4 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 2.8 REACTOME_SIGNALING_BY_SCF_KIT Genes involved in Signaling by SCF-KIT
0.0 0.5 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.7 REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.3 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.0 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation