Motif ID: Cebpb

Z-value: 0.693


Transcription factors associated with Cebpb:

Gene SymbolEntrez IDGene Name
Cebpb ENSMUSG00000056501.3 Cebpb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cebpbmm10_v2_chr2_+_167688915_1676889730.603.5e-05Click!


Activity profile for motif Cebpb.

activity profile for motif Cebpb


Sorted Z-values histogram for motif Cebpb

Sorted Z-values for motif Cebpb



Network of associatons between targets according to the STRING database.



First level regulatory network of Cebpb

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_15924928 3.382 ENSMUST00000025542.3
Psat1
phosphoserine aminotransferase 1
chr8_+_75093591 2.816 ENSMUST00000005548.6
Hmox1
heme oxygenase (decycling) 1
chr12_+_88953399 2.732 ENSMUST00000057634.7
Nrxn3
neurexin III
chr5_+_75152274 2.696 ENSMUST00000000476.8
Pdgfra
platelet derived growth factor receptor, alpha polypeptide
chr2_+_118111876 2.450 ENSMUST00000039559.8
Thbs1
thrombospondin 1
chr13_-_49309217 2.356 ENSMUST00000110087.2
Fgd3
FYVE, RhoGEF and PH domain containing 3
chr2_+_25180737 2.292 ENSMUST00000104999.2
Nrarp
Notch-regulated ankyrin repeat protein
chr14_+_65971049 2.155 ENSMUST00000128539.1
Clu
clusterin
chr1_-_71653162 2.131 ENSMUST00000055226.6
Fn1
fibronectin 1
chr4_-_148087961 2.100 ENSMUST00000030865.8
Agtrap
angiotensin II, type I receptor-associated protein
chr15_-_37459327 2.097 ENSMUST00000119730.1
ENSMUST00000120746.1
Ncald

neurocalcin delta

chr19_-_50678642 2.078 ENSMUST00000072685.6
ENSMUST00000164039.2
Sorcs1

VPS10 domain receptor protein SORCS 1

chr14_+_65971164 2.017 ENSMUST00000144619.1
Clu
clusterin
chr14_+_65970610 1.956 ENSMUST00000127387.1
Clu
clusterin
chr12_-_56535047 1.928 ENSMUST00000178477.2
Nkx2-1
NK2 homeobox 1
chr14_+_65970804 1.910 ENSMUST00000138191.1
Clu
clusterin
chr3_-_57575760 1.813 ENSMUST00000029380.7
Wwtr1
WW domain containing transcription regulator 1
chr7_+_126862431 1.598 ENSMUST00000132808.1
Hirip3
HIRA interacting protein 3
chr18_+_4994600 1.505 ENSMUST00000140448.1
Svil
supervillin
chr4_+_136172367 1.492 ENSMUST00000061721.5
E2f2
E2F transcription factor 2
chr15_-_37458523 1.440 ENSMUST00000116445.2
Ncald
neurocalcin delta
chr14_+_50944499 1.437 ENSMUST00000178092.1
Pnp
purine-nucleoside phosphorylase
chr3_+_66219909 1.417 ENSMUST00000029421.5
Ptx3
pentraxin related gene
chr2_+_119047116 1.406 ENSMUST00000152380.1
ENSMUST00000099542.2
Casc5

cancer susceptibility candidate 5

chr9_+_78615501 1.397 ENSMUST00000093812.4
Cd109
CD109 antigen
chr12_-_65172560 1.297 ENSMUST00000052201.8
Mis18bp1
MIS18 binding protein 1
chr7_+_126861947 1.249 ENSMUST00000037248.3
Hirip3
HIRA interacting protein 3
chr5_+_63812447 1.209 ENSMUST00000081747.3
0610040J01Rik
RIKEN cDNA 0610040J01 gene
chr2_+_119047129 1.193 ENSMUST00000153300.1
ENSMUST00000028799.5
Casc5

cancer susceptibility candidate 5

chr7_+_27447978 1.191 ENSMUST00000037399.9
ENSMUST00000108358.1
Blvrb

biliverdin reductase B (flavin reductase (NADPH))

chr14_-_122451109 1.139 ENSMUST00000081580.2
Gm5089
predicted gene 5089
chr4_-_151044564 1.115 ENSMUST00000103204.4
Per3
period circadian clock 3
chr6_+_54326955 1.098 ENSMUST00000059138.4
Prr15
proline rich 15
chr6_-_23248264 1.071 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr5_-_99037035 1.014 ENSMUST00000031277.6
Prkg2
protein kinase, cGMP-dependent, type II
chr17_+_86963077 0.985 ENSMUST00000024956.8
Rhoq
ras homolog gene family, member Q
chr18_-_38601268 0.978 ENSMUST00000025295.6
Spry4
sprouty homolog 4 (Drosophila)
chrX_-_57338598 0.960 ENSMUST00000033468.4
ENSMUST00000114736.1
Arhgef6

Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6

chr1_+_134182404 0.946 ENSMUST00000153856.1
ENSMUST00000082060.3
ENSMUST00000133701.1
ENSMUST00000132873.1
Chi3l1



chitinase 3-like 1



chr5_-_99037342 0.878 ENSMUST00000161490.1
Prkg2
protein kinase, cGMP-dependent, type II
chr10_+_93488766 0.853 ENSMUST00000129421.1
Hal
histidine ammonia lyase
chr3_+_87906842 0.841 ENSMUST00000159492.1
Hdgf
hepatoma-derived growth factor
chr4_-_133967235 0.810 ENSMUST00000123234.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr6_+_117907795 0.807 ENSMUST00000167657.1
Hnrnpf
heterogeneous nuclear ribonucleoprotein F
chr7_-_45830776 0.803 ENSMUST00000107723.2
ENSMUST00000131384.1
Grwd1

glutamate-rich WD repeat containing 1

chr7_-_12684991 0.791 ENSMUST00000172743.1
ENSMUST00000167771.1
Vmn2r55

vomeronasal 2, receptor 55

chr14_+_47001336 0.766 ENSMUST00000125113.1
Samd4
sterile alpha motif domain containing 4
chr12_+_74297474 0.726 ENSMUST00000072100.3
Dbpht2
DNA binding protein with his-thr domain
chr3_+_87906321 0.698 ENSMUST00000005017.8
Hdgf
hepatoma-derived growth factor
chr18_-_36726730 0.694 ENSMUST00000061829.6
Cd14
CD14 antigen
chr17_+_86963279 0.690 ENSMUST00000139344.1
Rhoq
ras homolog gene family, member Q
chr19_+_6401675 0.661 ENSMUST00000113471.1
ENSMUST00000113469.2
Rasgrp2

RAS, guanyl releasing protein 2

chr4_+_55350043 0.651 ENSMUST00000030134.8
Rad23b
RAD23b homolog (S. cerevisiae)
chr4_+_150237694 0.651 ENSMUST00000141931.1
Eno1
enolase 1, alpha non-neuron
chr5_-_148399901 0.642 ENSMUST00000048116.8
Slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr19_+_12460749 0.615 ENSMUST00000081035.7
Mpeg1
macrophage expressed gene 1
chr10_+_97482350 0.613 ENSMUST00000163448.2
Dcn
decorin
chr7_-_127273919 0.579 ENSMUST00000082428.3
Sephs2
selenophosphate synthetase 2
chr2_-_57113053 0.553 ENSMUST00000112627.1
Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr9_-_71163224 0.527 ENSMUST00000074465.2
Aqp9
aquaporin 9
chr18_-_34931931 0.521 ENSMUST00000180351.1
Etf1
eukaryotic translation termination factor 1
chr8_-_45410539 0.519 ENSMUST00000034056.4
ENSMUST00000167106.1
Tlr3

toll-like receptor 3

chr8_-_92355764 0.511 ENSMUST00000180102.1
ENSMUST00000179421.1
ENSMUST00000179222.1
ENSMUST00000179029.1
4933436C20Rik



RIKEN cDNA 4933436C20 gene



chrX_-_134600976 0.504 ENSMUST00000033621.6
Gla
galactosidase, alpha
chr11_+_53519725 0.496 ENSMUST00000108987.1
ENSMUST00000121334.1
ENSMUST00000117061.1
Sept8


septin 8


chr13_+_24614608 0.484 ENSMUST00000091694.3
Fam65b
family with sequence similarity 65, member B
chr5_+_31054766 0.484 ENSMUST00000013773.5
ENSMUST00000114646.1
Cad

carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase

chr15_-_101850778 0.483 ENSMUST00000023790.3
Krt1
keratin 1
chr17_-_35235755 0.482 ENSMUST00000048994.6
Nfkbil1
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor like 1
chr6_-_117907753 0.479 ENSMUST00000035534.4
4933440N22Rik
RIKEN cDNA 4933440N22 gene
chr15_+_87625214 0.475 ENSMUST00000068088.6
Fam19a5
family with sequence similarity 19, member A5
chr11_+_6415443 0.474 ENSMUST00000132846.1
Ppia
peptidylprolyl isomerase A
chr4_-_133967893 0.467 ENSMUST00000100472.3
ENSMUST00000136327.1
Hmgn2

high mobility group nucleosomal binding domain 2

chr5_+_31054821 0.456 ENSMUST00000174367.1
ENSMUST00000170329.1
ENSMUST00000031049.6
Cad


carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase


chr3_+_109123104 0.455 ENSMUST00000029477.6
Slc25a24
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 24
chrX_-_162565514 0.442 ENSMUST00000154424.1
Reps2
RALBP1 associated Eps domain containing protein 2
chr7_-_45434590 0.435 ENSMUST00000107771.3
ENSMUST00000141761.1
Ruvbl2

RuvB-like protein 2

chr8_+_94037198 0.417 ENSMUST00000109556.2
ENSMUST00000093301.2
ENSMUST00000060632.7
Ogfod1


2-oxoglutarate and iron-dependent oxygenase domain containing 1


chrX_+_134601271 0.414 ENSMUST00000050331.6
ENSMUST00000059297.5
Hnrnph2

heterogeneous nuclear ribonucleoprotein H2

chr4_-_43558386 0.409 ENSMUST00000130353.1
Tln1
talin 1
chrX_+_134601179 0.409 ENSMUST00000074950.4
ENSMUST00000113203.1
ENSMUST00000113202.1
Hnrnph2


heterogeneous nuclear ribonucleoprotein H2


chr12_-_51971289 0.384 ENSMUST00000040583.5
Heatr5a
HEAT repeat containing 5A
chr5_+_115279666 0.379 ENSMUST00000040421.4
Coq5
coenzyme Q5 homolog, methyltransferase (yeast)
chr14_-_98169542 0.370 ENSMUST00000069334.7
ENSMUST00000071533.6
Dach1

dachshund 1 (Drosophila)

chr11_+_97685903 0.368 ENSMUST00000107583.2
Cisd3
CDGSH iron sulfur domain 3
chr9_-_71771535 0.364 ENSMUST00000122065.1
ENSMUST00000121322.1
ENSMUST00000072899.2
Cgnl1


cingulin-like 1


chr11_+_110997487 0.358 ENSMUST00000106635.1
Kcnj16
potassium inwardly-rectifying channel, subfamily J, member 16
chr11_-_101551837 0.342 ENSMUST00000017290.4
Brca1
breast cancer 1
chr2_+_155751117 0.337 ENSMUST00000029140.5
ENSMUST00000132608.1
Procr

protein C receptor, endothelial

chr19_-_57239310 0.322 ENSMUST00000111559.1
Ablim1
actin-binding LIM protein 1
chr5_+_93093428 0.318 ENSMUST00000074733.7
Sept11
septin 11
chr10_+_80249106 0.316 ENSMUST00000105364.1
Ndufs7
NADH dehydrogenase (ubiquinone) Fe-S protein 7
chr11_+_100320596 0.302 ENSMUST00000152521.1
Eif1
eukaryotic translation initiation factor 1
chr17_+_32284772 0.301 ENSMUST00000181112.1
Gm26549
predicted gene, 26549
chr3_-_50443603 0.300 ENSMUST00000029297.4
Slc7a11
solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
chr11_-_99389351 0.299 ENSMUST00000103131.4
Krt10
keratin 10
chr13_+_31625802 0.298 ENSMUST00000042054.2
Foxf2
forkhead box F2
chr10_+_80249441 0.297 ENSMUST00000020361.6
Ndufs7
NADH dehydrogenase (ubiquinone) Fe-S protein 7
chr4_+_115057410 0.291 ENSMUST00000136946.1
Tal1
T cell acute lymphocytic leukemia 1
chr13_+_51100810 0.286 ENSMUST00000095797.5
Spin1
spindlin 1
chr2_+_158306493 0.284 ENSMUST00000016168.2
ENSMUST00000109491.1
Lbp

lipopolysaccharide binding protein

chr19_-_3929723 0.267 ENSMUST00000051803.6
Aldh3b1
aldehyde dehydrogenase 3 family, member B1
chr13_-_60936550 0.260 ENSMUST00000021880.9
Ctla2a
cytotoxic T lymphocyte-associated protein 2 alpha
chr11_+_99041237 0.241 ENSMUST00000017637.6
Igfbp4
insulin-like growth factor binding protein 4
chr12_-_84194007 0.226 ENSMUST00000110294.1
Elmsan1
ELM2 and Myb/SANT-like domain containing 1
chr1_+_36307745 0.200 ENSMUST00000142319.1
ENSMUST00000097778.2
ENSMUST00000115031.1
ENSMUST00000115032.1
ENSMUST00000137906.1
ENSMUST00000115029.1
Arid5a





AT rich interactive domain 5A (MRF1-like)





chr4_-_133967953 0.191 ENSMUST00000102553.4
Hmgn2
high mobility group nucleosomal binding domain 2
chr3_+_19957037 0.182 ENSMUST00000091309.5
ENSMUST00000108329.1
ENSMUST00000003714.6
Cp


ceruloplasmin


chr4_+_133176336 0.178 ENSMUST00000105912.1
Wasf2
WAS protein family, member 2
chr1_+_169655493 0.172 ENSMUST00000027997.3
Rgs5
regulator of G-protein signaling 5
chr15_+_59648644 0.168 ENSMUST00000118228.1
Trib1
tribbles homolog 1 (Drosophila)
chr18_-_64516547 0.163 ENSMUST00000025483.9
Nars
asparaginyl-tRNA synthetase
chr17_+_28858411 0.155 ENSMUST00000114737.1
ENSMUST00000056866.5
Pnpla1

patatin-like phospholipase domain containing 1

chr1_-_191183244 0.154 ENSMUST00000027941.8
Atf3
activating transcription factor 3
chr12_+_76837408 0.152 ENSMUST00000041008.9
Fntb
farnesyltransferase, CAAX box, beta
chr11_-_46166397 0.149 ENSMUST00000020679.2
Nipal4
NIPA-like domain containing 4
chr19_-_34877880 0.145 ENSMUST00000112460.1
Pank1
pantothenate kinase 1
chr4_-_108833544 0.138 ENSMUST00000102740.1
ENSMUST00000102741.1
Btf3l4

basic transcription factor 3-like 4

chr10_-_62507737 0.136 ENSMUST00000020271.6
Srgn
serglycin
chr5_+_145140362 0.135 ENSMUST00000162594.1
ENSMUST00000162308.1
ENSMUST00000159018.1
ENSMUST00000160075.1
Bud31



BUD31 homolog (yeast)



chr17_-_56121946 0.134 ENSMUST00000041357.7
Lrg1
leucine-rich alpha-2-glycoprotein 1
chr13_+_63014934 0.132 ENSMUST00000091560.4
2010111I01Rik
RIKEN cDNA 2010111I01 gene
chr14_+_66784523 0.118 ENSMUST00000071522.2
Gm10032
predicted gene 10032
chr11_-_83649349 0.116 ENSMUST00000001008.5
Ccl3
chemokine (C-C motif) ligand 3
chr10_-_121626316 0.110 ENSMUST00000039810.7
Xpot
exportin, tRNA (nuclear export receptor for tRNAs)
chr14_-_68655804 0.109 ENSMUST00000111072.1
ENSMUST00000022642.5
Adam28

a disintegrin and metallopeptidase domain 28

chr10_-_99759658 0.107 ENSMUST00000056085.4
Csl
citrate synthase like
chr3_+_96104498 0.095 ENSMUST00000132980.1
ENSMUST00000138206.1
ENSMUST00000090785.2
ENSMUST00000035519.5
Otud7b



OTU domain containing 7B



chr13_+_63015167 0.092 ENSMUST00000021911.8
2010111I01Rik
RIKEN cDNA 2010111I01 gene
chr11_+_62077018 0.088 ENSMUST00000092415.5
Specc1
sperm antigen with calponin homology and coiled-coil domains 1
chrX_-_139714481 0.087 ENSMUST00000183728.1
Gm15013
predicted gene 15013
chr8_-_33929798 0.087 ENSMUST00000033995.7
ENSMUST00000033994.8
ENSMUST00000053251.5
Rbpms


RNA binding protein gene with multiple splicing


chr15_-_96460838 0.083 ENSMUST00000047835.6
Scaf11
SR-related CTD-associated factor 11
chr18_-_52529692 0.082 ENSMUST00000025409.7
Lox
lysyl oxidase
chr7_+_103550368 0.070 ENSMUST00000106888.1
Olfr613
olfactory receptor 613
chr1_-_52500679 0.068 ENSMUST00000069792.7
Nab1
Ngfi-A binding protein 1
chr4_+_152039315 0.067 ENSMUST00000084116.6
ENSMUST00000105663.1
ENSMUST00000103197.3
Nol9


nucleolar protein 9


chr11_-_33203588 0.061 ENSMUST00000037746.6
Tlx3
T cell leukemia, homeobox 3
chr2_-_156180135 0.051 ENSMUST00000126992.1
ENSMUST00000146288.1
ENSMUST00000029149.6
ENSMUST00000109587.2
ENSMUST00000109584.1
Rbm39




RNA binding motif protein 39




chr14_+_99298652 0.048 ENSMUST00000005279.6
Klf5
Kruppel-like factor 5
chr15_+_59648350 0.047 ENSMUST00000067543.6
Trib1
tribbles homolog 1 (Drosophila)
chr7_+_24507006 0.036 ENSMUST00000176880.1
Zfp428
zinc finger protein 428
chr19_+_34290653 0.033 ENSMUST00000025691.5
ENSMUST00000112472.2
Fas

Fas (TNF receptor superfamily member 6)

chr11_-_78984831 0.024 ENSMUST00000073001.4
ENSMUST00000108269.3
Lgals9

lectin, galactose binding, soluble 9

chr17_+_48346401 0.023 ENSMUST00000024791.8
Trem2
triggering receptor expressed on myeloid cells 2
chr5_+_105876532 0.023 ENSMUST00000150440.1
ENSMUST00000031227.4
Zfp326

zinc finger protein 326

chr1_+_171345684 0.021 ENSMUST00000006579.4
Pfdn2
prefoldin 2
chr13_-_117025505 0.018 ENSMUST00000022239.6
Parp8
poly (ADP-ribose) polymerase family, member 8
chr14_-_54870913 0.008 ENSMUST00000146642.1
Homez
homeodomain leucine zipper-encoding gene
chr5_-_137533170 0.007 ENSMUST00000168746.1
ENSMUST00000170293.1
Gnb2

guanine nucleotide binding protein (G protein), beta 2

chr8_+_111033890 0.005 ENSMUST00000034441.7
Aars
alanyl-tRNA synthetase
chr7_+_19181159 0.000 ENSMUST00000120595.1
ENSMUST00000048502.8
Eml2

echinoderm microtubule associated protein like 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 8.0 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.9 2.7 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.8 2.4 GO:0010752 negative regulation of antigen processing and presentation(GO:0002578) negative regulation of nitric oxide mediated signal transduction(GO:0010751) regulation of cGMP-mediated signaling(GO:0010752)
0.7 2.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931) calcium-independent cell-matrix adhesion(GO:0007161) transforming growth factor-beta secretion(GO:0038044)
0.7 2.8 GO:1904706 heme oxidation(GO:0006788) negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.6 3.2 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.6 1.9 GO:0021759 globus pallidus development(GO:0021759)
0.5 1.4 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.4 1.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.3 1.2 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.3 1.4 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.3 1.4 GO:0072675 osteoclast fusion(GO:0072675)
0.3 1.9 GO:2001225 cellular hypotonic response(GO:0071476) regulation of chloride transport(GO:2001225)
0.3 1.8 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.2 0.9 GO:0006526 arginine biosynthetic process(GO:0006526)
0.2 0.7 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.2 0.9 GO:0006547 histidine metabolic process(GO:0006547) imidazole-containing compound catabolic process(GO:0052805)
0.2 1.5 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.2 2.3 GO:0014807 regulation of somitogenesis(GO:0014807)
0.2 0.7 GO:0071726 response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
0.2 0.5 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2 0.5 GO:0045349 regulation of dendritic cell cytokine production(GO:0002730) interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.1 2.1 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.1 0.4 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.1 0.6 GO:0001887 selenium compound metabolic process(GO:0001887) selenocysteine metabolic process(GO:0016259)
0.1 0.6 GO:0051866 general adaptation syndrome(GO:0051866)
0.1 2.7 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.1 0.4 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1 0.3 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.1 0.3 GO:0060217 hemangioblast cell differentiation(GO:0060217) regulation of mast cell differentiation(GO:0060375)
0.1 0.3 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.1 0.5 GO:0015867 ATP transport(GO:0015867)
0.1 0.5 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.1 0.5 GO:0015791 polyol transport(GO:0015791) bile acid secretion(GO:0032782)
0.1 0.2 GO:0045658 eosinophil differentiation(GO:0030222) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1 0.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 2.1 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 0.5 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1 1.5 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.1 0.9 GO:0006415 translational termination(GO:0006415)
0.0 0.2 GO:2000318 positive regulation of T-helper 17 type immune response(GO:2000318)
0.0 0.7 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 3.5 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.2 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.2 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0 0.2 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.4 GO:0015809 arginine transport(GO:0015809)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 2.4 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.3 GO:1902475 L-glutamate transmembrane transport(GO:0089711) L-alpha-amino acid transmembrane transport(GO:1902475)
0.0 0.1 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.5 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.2 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.3 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.1 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.0 0.4 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 1.1 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.6 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.4 GO:0010107 potassium ion import(GO:0010107)
0.0 1.0 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 0.3 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.3 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.3 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0 0.3 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 0.0 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.0 0.2 GO:0046688 response to copper ion(GO:0046688)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.6 GO:0005577 fibrinogen complex(GO:0005577)
1.1 8.0 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.2 0.7 GO:0071942 XPC complex(GO:0071942)
0.1 0.7 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.3 GO:0033193 Lsd1/2 complex(GO:0033193)
0.1 0.5 GO:0001533 cornified envelope(GO:0001533)
0.1 1.3 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.1 0.7 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.4 GO:0097255 R2TP complex(GO:0097255)
0.1 0.3 GO:0070531 BRCA1-A complex(GO:0070531)
0.1 0.2 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.6 GO:0098644 complex of collagen trimers(GO:0098644)
0.0 2.7 GO:0005902 microvillus(GO:0005902)
0.0 0.3 GO:0045095 keratin filament(GO:0045095)
0.0 2.0 GO:0042734 presynaptic membrane(GO:0042734)
0.0 2.7 GO:0005901 caveola(GO:0005901)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 2.1 GO:0043195 terminal bouton(GO:0043195)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 1.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 5.6 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.5 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.6 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0070052 collagen V binding(GO:0070052)
0.7 2.8 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.5 2.7 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.5 1.4 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.5 1.9 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.4 2.1 GO:0045340 mercury ion binding(GO:0045340)
0.3 8.0 GO:0051787 misfolded protein binding(GO:0051787)
0.3 1.0 GO:0071723 lipopeptide binding(GO:0071723)
0.3 1.2 GO:0004074 biliverdin reductase activity(GO:0004074)
0.2 0.9 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.2 1.4 GO:0001849 complement component C1q binding(GO:0001849)
0.2 0.9 GO:0016841 ammonia-lyase activity(GO:0016841)
0.2 3.4 GO:0008483 transaminase activity(GO:0008483)
0.2 1.9 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.1 0.5 GO:0015254 glycerol channel activity(GO:0015254)
0.1 1.7 GO:0005522 profilin binding(GO:0005522)
0.1 3.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.5 GO:0016936 galactoside binding(GO:0016936)
0.1 0.6 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 0.2 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 0.3 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.1 0.4 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 0.7 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.5 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.3 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1 0.5 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 2.7 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 1.4 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 0.8 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.2 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
0.0 0.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.6 GO:0048038 quinone binding(GO:0048038)
0.0 0.4 GO:0031543 peptidyl-proline dioxygenase activity(GO:0031543)
0.0 1.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 2.1 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.0 0.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.8 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.8 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 2.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.4 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 1.0 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.2 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.2 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.2 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.2 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.7 GO:0005518 collagen binding(GO:0005518)
0.0 0.0 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.0 0.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.6 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.1 3.4 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 1.5 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 7.7 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.1 2.7 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.0 1.2 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 1.9 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.1 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 1.1 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.4 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 1.1 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.0 0.4 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 1.6 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.0 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 3.3 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 2.5 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 11.1 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 3.3 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.9 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 1.5 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 1.3 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.1 1.2 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 3.9 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 0.5 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.8 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.6 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.0 1.0 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.7 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.0 1.5 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.7 REACTOME_INTEGRIN_ALPHAIIB_BETA3_SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 2.7 REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.3 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 1.8 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.8 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.4 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.7 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.4 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.0 1.7 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.5 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.2 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.6 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.0 0.1 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism