Motif ID: Pparg_Rxrg

Z-value: 1.191

Transcription factors associated with Pparg_Rxrg:

Gene SymbolEntrez IDGene Name
Pparg ENSMUSG00000000440.6 Pparg
Rxrg ENSMUSG00000015843.4 Rxrg

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rxrgmm10_v2_chr1_+_167598384_167598411-0.221.6e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Pparg_Rxrg

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_126556128 5.112 ENSMUST00000141482.2
Slc27a2
solute carrier family 27 (fatty acid transporter), member 2
chr4_-_126736236 3.406 ENSMUST00000048194.7
Tfap2e
transcription factor AP-2, epsilon
chr11_-_100759942 3.244 ENSMUST00000107363.2
Kcnh4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr6_+_34354119 3.159 ENSMUST00000038406.6
Akr1b8
aldo-keto reductase family 1, member B8
chr4_+_9269285 3.122 ENSMUST00000038841.7
Clvs1
clavesin 1
chr1_-_138847579 3.037 ENSMUST00000093486.3
ENSMUST00000046870.6
Lhx9

LIM homeobox protein 9

chr9_+_118506226 2.916 ENSMUST00000084820.4
Golga4
golgi autoantigen, golgin subfamily a, 4
chr3_+_87948666 2.822 ENSMUST00000005019.5
Crabp2
cellular retinoic acid binding protein II
chr12_+_109452833 2.519 ENSMUST00000056110.8
Dlk1
delta-like 1 homolog (Drosophila)
chr7_+_4925802 2.495 ENSMUST00000057612.7
Ssc5d
scavenger receptor cysteine rich domain containing (5 domains)
chr2_+_165595009 2.387 ENSMUST00000088132.6
Eya2
eyes absent 2 homolog (Drosophila)
chr14_+_54476100 2.265 ENSMUST00000164766.1
ENSMUST00000164697.1
Rem2

rad and gem related GTP binding protein 2

chr6_+_7844806 2.116 ENSMUST00000040159.4
C1galt1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr2_-_79456750 2.114 ENSMUST00000041099.4
Neurod1
neurogenic differentiation 1
chr2_-_117342831 2.110 ENSMUST00000178884.1
Rasgrp1
RAS guanyl releasing protein 1
chr9_-_106656081 1.777 ENSMUST00000023959.7
Grm2
glutamate receptor, metabotropic 2
chr17_+_32621319 1.714 ENSMUST00000077639.5
Gm9705
predicted gene 9705
chr11_+_23666479 1.675 ENSMUST00000143117.1
Pus10
pseudouridylate synthase 10
chr7_-_143756985 1.640 ENSMUST00000134056.1
Osbpl5
oxysterol binding protein-like 5
chr9_-_37552904 1.601 ENSMUST00000065668.5
Nrgn
neurogranin
chr7_-_103843154 1.597 ENSMUST00000063957.4
Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr5_+_76840597 1.565 ENSMUST00000120639.2
ENSMUST00000163347.1
ENSMUST00000121851.1
C530008M17Rik


RIKEN cDNA C530008M17 gene


chr2_+_165655237 1.537 ENSMUST00000063433.7
Eya2
eyes absent 2 homolog (Drosophila)
chr11_+_61485431 1.385 ENSMUST00000064783.3
ENSMUST00000040522.6
Mfap4

microfibrillar-associated protein 4

chr11_+_84525669 1.384 ENSMUST00000126072.1
ENSMUST00000128121.1
1500016L03Rik

RIKEN cDNA 1500016L03 gene

chr9_-_42399709 1.335 ENSMUST00000160940.1
Tecta
tectorin alpha
chr2_-_180104463 1.331 ENSMUST00000056480.3
Hrh3
histamine receptor H3
chr9_-_42399915 1.324 ENSMUST00000042190.7
Tecta
tectorin alpha
chr5_+_92571477 1.319 ENSMUST00000176621.1
ENSMUST00000175974.1
ENSMUST00000131166.2
ENSMUST00000176448.1
Fam47e



family with sequence similarity 47, member E



chr7_+_31059342 1.298 ENSMUST00000039775.7
Lgi4
leucine-rich repeat LGI family, member 4
chr3_+_156562141 1.284 ENSMUST00000175773.1
Negr1
neuronal growth regulator 1
chr10_-_119240006 1.274 ENSMUST00000020315.6
Cand1
cullin associated and neddylation disassociated 1
chr4_+_42240639 1.254 ENSMUST00000117202.2
Gm10600
predicted gene 10600
chr3_-_59344256 1.240 ENSMUST00000039419.6
Igsf10
immunoglobulin superfamily, member 10
chr2_-_130840091 1.216 ENSMUST00000044766.8
ENSMUST00000138990.1
ENSMUST00000120316.1
ENSMUST00000110243.1
4930402H24Rik



RIKEN cDNA 4930402H24 gene



chr10_+_18845071 1.171 ENSMUST00000019998.7
Perp
PERP, TP53 apoptosis effector
chr2_-_38287347 1.171 ENSMUST00000102787.3
Dennd1a
DENN/MADD domain containing 1A
chr2_-_38287174 1.169 ENSMUST00000130472.1
Dennd1a
DENN/MADD domain containing 1A
chr1_-_64122256 1.163 ENSMUST00000135075.1
Klf7
Kruppel-like factor 7 (ubiquitous)
chr11_-_100939357 1.163 ENSMUST00000092671.5
ENSMUST00000103114.1
Stat3

signal transducer and activator of transcription 3

chr18_+_63708689 1.161 ENSMUST00000072726.5
Wdr7
WD repeat domain 7
chr12_+_17690793 1.158 ENSMUST00000071858.3
Hpcal1
hippocalcin-like 1
chr17_-_23844155 1.151 ENSMUST00000122936.1
ENSMUST00000024926.7
ENSMUST00000151797.1
Prss41


protease, serine, 41


chr4_+_59581563 1.147 ENSMUST00000030078.5
Hsdl2
hydroxysteroid dehydrogenase like 2
chr11_-_100939457 1.144 ENSMUST00000138438.1
Stat3
signal transducer and activator of transcription 3
chr11_+_84525647 1.106 ENSMUST00000134800.1
1500016L03Rik
RIKEN cDNA 1500016L03 gene
chr11_-_100939540 1.100 ENSMUST00000127638.1
Stat3
signal transducer and activator of transcription 3
chr4_+_118429701 1.092 ENSMUST00000067896.3
Elovl1
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1
chr9_-_50739365 1.071 ENSMUST00000117093.1
ENSMUST00000121634.1
Dixdc1

DIX domain containing 1

chr9_-_55048544 1.068 ENSMUST00000034854.6
Chrnb4
cholinergic receptor, nicotinic, beta polypeptide 4
chr2_-_160872829 1.058 ENSMUST00000176141.1
Zhx3
zinc fingers and homeoboxes 3
chr7_+_114768736 1.050 ENSMUST00000117543.1
Insc
inscuteable homolog (Drosophila)
chr2_+_102706356 1.038 ENSMUST00000123759.1
ENSMUST00000111212.1
ENSMUST00000005220.4
Slc1a2


solute carrier family 1 (glial high affinity glutamate transporter), member 2


chr7_-_43313063 1.033 ENSMUST00000135130.1
ENSMUST00000139061.1
Zfp715

zinc finger protein 715

chr6_+_34384218 1.024 ENSMUST00000038383.7
ENSMUST00000115051.1
Akr1b10

aldo-keto reductase family 1, member B10 (aldose reductase)

chr5_-_24329556 1.013 ENSMUST00000115098.2
Kcnh2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr7_-_142899985 1.009 ENSMUST00000000219.3
Th
tyrosine hydroxylase
chr4_+_126556994 0.996 ENSMUST00000147675.1
Clspn
claspin
chr13_-_64248495 0.993 ENSMUST00000109769.2
Cdc14b
CDC14 cell division cycle 14B
chr6_+_83137089 0.977 ENSMUST00000121093.1
ENSMUST00000087938.4
Rtkn

rhotekin

chr4_+_148602527 0.968 ENSMUST00000105701.2
ENSMUST00000052060.6
Masp2

mannan-binding lectin serine peptidase 2

chr4_-_155043143 0.966 ENSMUST00000135665.2
Plch2
phospholipase C, eta 2
chr9_+_46012810 0.964 ENSMUST00000126865.1
Sik3
SIK family kinase 3
chr19_+_46707443 0.956 ENSMUST00000003655.7
As3mt
arsenic (+3 oxidation state) methyltransferase
chr9_-_58159201 0.953 ENSMUST00000041477.7
Islr
immunoglobulin superfamily containing leucine-rich repeat
chr10_+_128790903 0.945 ENSMUST00000026411.6
Mmp19
matrix metallopeptidase 19
chr11_+_23666007 0.933 ENSMUST00000058163.4
Pus10
pseudouridylate synthase 10
chr4_-_145194999 0.916 ENSMUST00000036579.7
Vps13d
vacuolar protein sorting 13 D (yeast)
chr2_-_154603698 0.914 ENSMUST00000000896.4
Pxmp4
peroxisomal membrane protein 4
chr2_-_130839683 0.914 ENSMUST00000119422.1
4930402H24Rik
RIKEN cDNA 4930402H24 gene
chr19_-_5683343 0.904 ENSMUST00000127876.1
Pcnxl3
pecanex-like 3 (Drosophila)
chr11_+_3488275 0.904 ENSMUST00000064265.6
Pla2g3
phospholipase A2, group III
chr11_+_67078293 0.889 ENSMUST00000108689.1
ENSMUST00000165221.1
ENSMUST00000007301.7
Myh3


myosin, heavy polypeptide 3, skeletal muscle, embryonic


chr12_-_16800674 0.884 ENSMUST00000162112.1
Greb1
gene regulated by estrogen in breast cancer protein
chr12_-_100899436 0.878 ENSMUST00000053668.3
Gpr68
G protein-coupled receptor 68
chr8_+_3655762 0.875 ENSMUST00000012849.8
ENSMUST00000169234.2
Retn

resistin

chr14_+_59201209 0.869 ENSMUST00000173547.1
ENSMUST00000043227.6
ENSMUST00000022551.7
Rcbtb1


regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1


chr17_-_56290499 0.860 ENSMUST00000019726.6
Plin3
perilipin 3
chr10_+_112271123 0.859 ENSMUST00000092175.2
Kcnc2
potassium voltage gated channel, Shaw-related subfamily, member 2
chr2_+_152081529 0.857 ENSMUST00000064061.3
Scrt2
scratch homolog 2, zinc finger protein (Drosophila)
chr2_-_181043540 0.844 ENSMUST00000124400.1
Chrna4
cholinergic receptor, nicotinic, alpha polypeptide 4
chr15_-_72546279 0.839 ENSMUST00000044624.6
Kcnk9
potassium channel, subfamily K, member 9
chr11_-_86993682 0.829 ENSMUST00000018571.4
Ypel2
yippee-like 2 (Drosophila)
chr6_+_83156401 0.828 ENSMUST00000032106.4
1700003E16Rik
RIKEN cDNA 1700003E16 gene
chr11_+_49203285 0.826 ENSMUST00000109198.1
ENSMUST00000137061.2
Zfp62

zinc finger protein 62

chr7_+_141468776 0.820 ENSMUST00000058746.5
Cd151
CD151 antigen
chr5_+_57718021 0.805 ENSMUST00000094783.3
ENSMUST00000068110.7
Pcdh7

protocadherin 7

chr3_-_88455302 0.805 ENSMUST00000125526.1
Sema4a
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr17_-_45686120 0.800 ENSMUST00000143907.1
ENSMUST00000127065.1
Tmem63b

transmembrane protein 63b

chr12_+_52699297 0.795 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chr2_-_151973387 0.788 ENSMUST00000109863.1
Fam110a
family with sequence similarity 110, member A
chr2_-_121442574 0.787 ENSMUST00000116432.1
Ell3
elongation factor RNA polymerase II-like 3
chr11_+_116593687 0.775 ENSMUST00000153476.1
Aanat
arylalkylamine N-acetyltransferase
chr11_+_44617310 0.771 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
Ebf1


early B cell factor 1


chr4_+_43875524 0.754 ENSMUST00000030198.6
Reck
reversion-inducing-cysteine-rich protein with kazal motifs
chr6_-_122340499 0.752 ENSMUST00000160843.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr9_+_46012822 0.746 ENSMUST00000120463.2
ENSMUST00000120247.1
Sik3

SIK family kinase 3

chr6_-_50261943 0.738 ENSMUST00000167893.1
Dfna5
deafness, autosomal dominant 5 (human)
chr4_+_59581645 0.736 ENSMUST00000107528.1
Hsdl2
hydroxysteroid dehydrogenase like 2
chr4_-_149909719 0.732 ENSMUST00000105685.1
Spsb1
splA/ryanodine receptor domain and SOCS box containing 1
chr11_-_102897123 0.727 ENSMUST00000067444.3
Gfap
glial fibrillary acidic protein
chr1_+_191025350 0.726 ENSMUST00000181050.1
A230020J21Rik
RIKEN cDNA A230020J21 gene
chrX_+_74424632 0.723 ENSMUST00000114129.2
ENSMUST00000132749.1
Ikbkg

inhibitor of kappaB kinase gamma

chr13_-_12106945 0.721 ENSMUST00000021750.7
ENSMUST00000170156.2
Ryr2

ryanodine receptor 2, cardiac

chr6_-_38837224 0.718 ENSMUST00000160962.1
Hipk2
homeodomain interacting protein kinase 2
chr5_-_38480131 0.717 ENSMUST00000143758.1
ENSMUST00000067886.5
Slc2a9

solute carrier family 2 (facilitated glucose transporter), member 9

chr13_-_41847626 0.715 ENSMUST00000121404.1
Adtrp
androgen dependent TFPI regulating protein
chr12_+_59130767 0.710 ENSMUST00000175877.1
Ctage5
CTAGE family, member 5
chr11_-_102897146 0.710 ENSMUST00000077902.4
Gfap
glial fibrillary acidic protein
chr7_+_122289297 0.708 ENSMUST00000064989.5
ENSMUST00000064921.4
Prkcb

protein kinase C, beta

chr2_+_154436437 0.708 ENSMUST00000109725.1
ENSMUST00000099178.3
ENSMUST00000045270.8
ENSMUST00000109724.1
Cbfa2t2



core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human)



chr4_-_110287479 0.707 ENSMUST00000106598.1
ENSMUST00000102723.4
ENSMUST00000153906.1
Elavl4


ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)


chr2_-_103797617 0.703 ENSMUST00000028607.6
Caprin1
cell cycle associated protein 1
chr7_-_43313233 0.701 ENSMUST00000012796.7
ENSMUST00000107986.2
Zfp715

zinc finger protein 715

chr11_+_93098404 0.700 ENSMUST00000107859.1
ENSMUST00000042943.6
ENSMUST00000107861.1
ENSMUST00000107858.2
Car10



carbonic anhydrase 10



chr15_+_89532816 0.698 ENSMUST00000167173.1
Shank3
SH3/ankyrin domain gene 3
chr1_+_74506044 0.695 ENSMUST00000087215.5
Rqcd1
rcd1 (required for cell differentiation) homolog 1 (S. pombe)
chr11_-_54962903 0.690 ENSMUST00000108885.1
ENSMUST00000102730.2
ENSMUST00000018482.6
ENSMUST00000108886.1
ENSMUST00000102731.1
Tnip1




TNFAIP3 interacting protein 1




chr11_-_100354040 0.690 ENSMUST00000173630.1
Hap1
huntingtin-associated protein 1
chr12_+_59131286 0.689 ENSMUST00000176464.1
ENSMUST00000170992.2
ENSMUST00000176322.1
Ctage5


CTAGE family, member 5


chr2_+_158306493 0.687 ENSMUST00000016168.2
ENSMUST00000109491.1
Lbp

lipopolysaccharide binding protein

chr12_+_104214538 0.686 ENSMUST00000121337.1
ENSMUST00000167049.1
ENSMUST00000101080.1
Serpina3f


serine (or cysteine) peptidase inhibitor, clade A, member 3F


chr8_-_57652993 0.685 ENSMUST00000110316.2
Galnt7
UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7
chr2_+_104095796 0.684 ENSMUST00000040423.5
ENSMUST00000168176.1
Cd59a

CD59a antigen

chr3_+_27317028 0.683 ENSMUST00000046383.5
ENSMUST00000174840.1
Tnfsf10

tumor necrosis factor (ligand) superfamily, member 10

chr4_-_118409219 0.677 ENSMUST00000075406.5
Szt2
seizure threshold 2
chr11_-_68927049 0.675 ENSMUST00000038932.7
Odf4
outer dense fiber of sperm tails 4
chr16_-_46010212 0.675 ENSMUST00000130481.1
Plcxd2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr10_-_80261004 0.673 ENSMUST00000105363.1
Gamt
guanidinoacetate methyltransferase
chr18_-_88927447 0.670 ENSMUST00000147313.1
Socs6
suppressor of cytokine signaling 6
chr2_-_125782834 0.667 ENSMUST00000053699.6
Secisbp2l
SECIS binding protein 2-like
chr6_+_48841633 0.665 ENSMUST00000168406.1
Tmem176a
transmembrane protein 176A
chrX_-_109013389 0.663 ENSMUST00000033597.8
Hmgn5
high-mobility group nucleosome binding domain 5
chr11_+_70657687 0.657 ENSMUST00000134087.1
ENSMUST00000170716.1
Eno3

enolase 3, beta muscle

chr6_-_148896150 0.656 ENSMUST00000072324.5
ENSMUST00000111569.2
Caprin2

caprin family member 2

chr5_-_24351604 0.653 ENSMUST00000036092.7
Kcnh2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr1_+_6487231 0.649 ENSMUST00000140079.1
ENSMUST00000131494.1
St18

suppression of tumorigenicity 18

chr10_-_80260959 0.648 ENSMUST00000020359.6
Gamt
guanidinoacetate methyltransferase
chr17_-_57078490 0.646 ENSMUST00000011623.7
Dennd1c
DENN/MADD domain containing 1C
chr3_-_90389884 0.646 ENSMUST00000029541.5
Slc27a3
solute carrier family 27 (fatty acid transporter), member 3
chr3_-_116712696 0.645 ENSMUST00000169530.1
Slc35a3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr1_-_169969143 0.645 ENSMUST00000027989.6
ENSMUST00000111353.3
Hsd17b7

hydroxysteroid (17-beta) dehydrogenase 7

chr11_+_75468040 0.644 ENSMUST00000043598.7
ENSMUST00000108435.1
Tlcd2

TLC domain containing 2

chr17_+_21657582 0.639 ENSMUST00000039726.7
3110052M02Rik
RIKEN cDNA 3110052M02 gene
chr17_-_73950172 0.636 ENSMUST00000024866.4
Xdh
xanthine dehydrogenase
chr11_+_77462325 0.633 ENSMUST00000102493.1
Coro6
coronin 6
chr10_-_81202037 0.632 ENSMUST00000005069.6
Nmrk2
nicotinamide riboside kinase 2
chr17_-_15564322 0.627 ENSMUST00000147532.1
Prdm9
PR domain containing 9
chr11_-_70656467 0.622 ENSMUST00000131642.1
Gm12319
predicted gene 12319
chr18_-_31911903 0.621 ENSMUST00000054984.6
Sft2d3
SFT2 domain containing 3
chr12_+_59130994 0.621 ENSMUST00000177460.1
Ctage5
CTAGE family, member 5
chr2_-_112480817 0.618 ENSMUST00000099589.2
Chrm5
cholinergic receptor, muscarinic 5
chr4_-_129248431 0.616 ENSMUST00000052602.5
C77080
expressed sequence C77080
chr6_+_48841476 0.613 ENSMUST00000101426.4
Tmem176a
transmembrane protein 176A
chr10_+_94147982 0.612 ENSMUST00000105290.2
Nr2c1
nuclear receptor subfamily 2, group C, member 1
chr17_+_45555693 0.611 ENSMUST00000024742.7
Nfkbie
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon
chr13_+_3634032 0.605 ENSMUST00000042288.6
Asb13
ankyrin repeat and SOCS box-containing 13
chrX_-_142390491 0.600 ENSMUST00000112904.1
ENSMUST00000112903.1
ENSMUST00000033634.4
Acsl4


acyl-CoA synthetase long-chain family member 4


chr17_-_50094277 0.599 ENSMUST00000113195.1
Rftn1
raftlin lipid raft linker 1
chrX_+_73639414 0.598 ENSMUST00000019701.8
Dusp9
dual specificity phosphatase 9
chr8_-_41016295 0.596 ENSMUST00000131965.1
Mtus1
mitochondrial tumor suppressor 1
chr16_+_20674111 0.591 ENSMUST00000151679.1
Eif4g1
eukaryotic translation initiation factor 4, gamma 1
chr7_+_139400489 0.585 ENSMUST00000097975.2
Inpp5a
inositol polyphosphate-5-phosphatase A
chr8_-_4216912 0.583 ENSMUST00000177491.1
BC068157
cDNA sequence BC068157
chr8_-_4217261 0.581 ENSMUST00000168386.2
BC068157
cDNA sequence BC068157
chr5_-_33218229 0.578 ENSMUST00000046186.4
Spon2
spondin 2, extracellular matrix protein
chr5_-_115119277 0.575 ENSMUST00000031524.7
Acads
acyl-Coenzyme A dehydrogenase, short chain
chr11_+_48837465 0.574 ENSMUST00000046903.5
Trim7
tripartite motif-containing 7
chr14_-_79868398 0.573 ENSMUST00000179430.1
Gm10845
predicted gene 10845
chr8_-_4217133 0.573 ENSMUST00000175906.1
BC068157
cDNA sequence BC068157
chr3_-_88455692 0.573 ENSMUST00000107531.1
Sema4a
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr3_+_95164306 0.573 ENSMUST00000107217.1
ENSMUST00000168321.1
Sema6c

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C

chr6_-_134566913 0.562 ENSMUST00000032322.8
Lrp6
low density lipoprotein receptor-related protein 6
chr5_-_120467296 0.562 ENSMUST00000132916.1
Sdsl
serine dehydratase-like
chr4_+_131873608 0.560 ENSMUST00000053819.3
Srsf4
serine/arginine-rich splicing factor 4
chr7_-_4866161 0.551 ENSMUST00000064547.5
Isoc2b
isochorismatase domain containing 2b
chr14_+_55618023 0.545 ENSMUST00000002395.7
Rec8
REC8 homolog (yeast)
chr17_-_45685973 0.542 ENSMUST00000145873.1
Tmem63b
transmembrane protein 63b
chr8_-_87804411 0.540 ENSMUST00000165770.2
Zfp423
zinc finger protein 423
chr14_+_25459267 0.539 ENSMUST00000007961.8
Zmiz1
zinc finger, MIZ-type containing 1
chr15_+_81235499 0.538 ENSMUST00000166855.1
Mchr1
melanin-concentrating hormone receptor 1
chr4_-_132422484 0.537 ENSMUST00000102568.3
Phactr4
phosphatase and actin regulator 4
chr8_-_57653023 0.533 ENSMUST00000034021.5
Galnt7
UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7
chr15_-_89425856 0.531 ENSMUST00000109313.2
Cpt1b
carnitine palmitoyltransferase 1b, muscle
chr11_+_74649462 0.530 ENSMUST00000092915.5
ENSMUST00000117818.1
Cluh

clustered mitochondria (cluA/CLU1) homolog

chr4_-_132422394 0.528 ENSMUST00000152271.1
ENSMUST00000084170.5
Phactr4

phosphatase and actin regulator 4

chr11_-_118401826 0.526 ENSMUST00000106290.3
ENSMUST00000043722.3
Lgals3bp

lectin, galactoside-binding, soluble, 3 binding protein

chr5_-_137611372 0.526 ENSMUST00000054564.6
Pcolce
procollagen C-endopeptidase enhancer protein
chr4_+_86930691 0.522 ENSMUST00000164590.1
Acer2
alkaline ceramidase 2
chr10_-_127288851 0.522 ENSMUST00000156208.1
ENSMUST00000026476.6
Mbd6

methyl-CpG binding domain protein 6

chr1_-_128592284 0.521 ENSMUST00000052172.6
ENSMUST00000142893.1
Cxcr4

chemokine (C-X-C motif) receptor 4

chr1_-_180195981 0.521 ENSMUST00000027766.6
ENSMUST00000161814.1
Adck3

aarF domain containing kinase 3

chr12_+_76444560 0.520 ENSMUST00000101281.2
Gm10451
predicted gene 10451
chr1_+_153749496 0.518 ENSMUST00000182722.1
Rnasel
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
chr9_-_105495475 0.517 ENSMUST00000176036.1
Atp2c1
ATPase, Ca++-sequestering
chrX_+_135839034 0.516 ENSMUST00000173804.1
ENSMUST00000113136.1
Gprasp2

G protein-coupled receptor associated sorting protein 2

chr2_+_3118407 0.515 ENSMUST00000091505.4
Fam171a1
family with sequence similarity 171, member A1
chr4_+_110397764 0.511 ENSMUST00000097920.2
ENSMUST00000080744.6
Agbl4

ATP/GTP binding protein-like 4

chr10_-_85127977 0.511 ENSMUST00000050813.2
Mterfd3
MTERF domain containing 3
chr6_-_50261743 0.510 ENSMUST00000101405.3
ENSMUST00000165099.1
ENSMUST00000170142.1
Dfna5


deafness, autosomal dominant 5 (human)



Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.1 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
1.1 3.2 GO:0016095 polyprenol catabolic process(GO:0016095) terpenoid catabolic process(GO:0016115) primary alcohol catabolic process(GO:0034310)
0.9 3.4 GO:1902724 positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.6 3.0 GO:0035262 gonad morphogenesis(GO:0035262)
0.5 2.1 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.5 4.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.5 0.5 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905024)
0.4 1.3 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.4 1.3 GO:0006601 creatine biosynthetic process(GO:0006601)
0.4 2.5 GO:2000483 detection of bacterium(GO:0016045) detection of other organism(GO:0098543) negative regulation of interleukin-8 secretion(GO:2000483)
0.4 2.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.4 1.1 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.4 2.1 GO:0016266 O-glycan processing(GO:0016266)
0.3 1.6 GO:0015671 oxygen transport(GO:0015671)
0.3 0.9 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.3 0.9 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.3 2.0 GO:1902302 regulation of potassium ion export(GO:1902302)
0.3 2.8 GO:0042573 retinoic acid metabolic process(GO:0042573)
0.3 0.8 GO:1903048 regulation of acetylcholine-gated cation channel activity(GO:1903048)
0.3 1.1 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.3 1.1 GO:0042414 epinephrine metabolic process(GO:0042414)
0.3 1.1 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.3 1.3 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.2 0.7 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.2 2.1 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.2 0.7 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.2 0.7 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.2 1.6 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.2 2.3 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.2 0.9 GO:0019372 lipoxygenase pathway(GO:0019372)
0.2 0.6 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.2 2.1 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.2 0.4 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.2 1.4 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
0.2 1.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 0.8 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.2 0.6 GO:0061324 mammary placode formation(GO:0060596) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.2 1.6 GO:0042940 D-amino acid transport(GO:0042940)
0.2 0.5 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.2 0.7 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.2 0.9 GO:0042701 progesterone secretion(GO:0042701)
0.2 0.7 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.2 0.7 GO:0035937 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.2 0.9 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
0.2 0.5 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.2 1.5 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.2 0.3 GO:1904058 positive regulation of sensory perception of pain(GO:1904058)
0.2 0.7 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.2 0.5 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.2 0.8 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.2 0.5 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678)
0.2 0.8 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.2 0.9 GO:0002934 desmosome organization(GO:0002934)
0.2 0.5 GO:0043686 co-translational protein modification(GO:0043686)
0.1 0.4 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.1 1.0 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.4 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1 0.4 GO:0071600 otic vesicle morphogenesis(GO:0071600)
0.1 0.6 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.1 1.0 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.7 GO:0032901 positive regulation of neurotrophin production(GO:0032901)
0.1 0.7 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.1 0.4 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.1 0.4 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.1 0.4 GO:0001803 type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.1 0.4 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.1 0.5 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.1 1.3 GO:0032306 regulation of prostaglandin secretion(GO:0032306)
0.1 0.6 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 0.6 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 1.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.1 0.9 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 0.4 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.1 0.1 GO:0002086 diaphragm contraction(GO:0002086)
0.1 0.3 GO:0019085 early viral transcription(GO:0019085)
0.1 0.5 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 2.2 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.1 0.3 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.1 0.3 GO:0015793 glycerol transport(GO:0015793)
0.1 0.6 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 0.3 GO:0002842 positive regulation of T cell mediated immune response to tumor cell(GO:0002842) protein import into mitochondrial intermembrane space(GO:0045041)
0.1 1.3 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 0.5 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.1 0.3 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1 0.6 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.1 0.4 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1 0.2 GO:0032229 positive regulation of gamma-aminobutyric acid secretion(GO:0014054) negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.1 0.3 GO:0090274 positive regulation of somatostatin secretion(GO:0090274)
0.1 1.0 GO:1904668 mitotic spindle midzone assembly(GO:0051256) positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 1.1 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.6 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.1 0.2 GO:0010666 positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.1 0.4 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.3 GO:0006776 vitamin A metabolic process(GO:0006776)
0.1 1.1 GO:0009404 toxin metabolic process(GO:0009404)
0.1 1.1 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.1 0.6 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.8 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 0.4 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.1 0.5 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.1 0.5 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 0.7 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 0.3 GO:1902605 heterotrimeric G-protein complex assembly(GO:1902605)
0.1 0.7 GO:0046415 urate metabolic process(GO:0046415)
0.1 0.3 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.1 1.1 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 0.3 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.7 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.1 0.3 GO:0038095 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Fc-epsilon receptor signaling pathway(GO:0038095) Kit signaling pathway(GO:0038109)
0.1 0.8 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.4 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.7 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.1 0.6 GO:0008228 opsonization(GO:0008228)
0.1 0.5 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.1 1.2 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 0.3 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
0.1 0.7 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.1 0.2 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.1 0.7 GO:0015684 ferrous iron transport(GO:0015684)
0.1 0.1 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 0.3 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.1 GO:0072592 oxygen metabolic process(GO:0072592)
0.1 0.2 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.1 0.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.4 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) phosphate ion transmembrane transport(GO:0035435) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 0.5 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.1 0.2 GO:0042732 D-xylose metabolic process(GO:0042732)
0.1 0.5 GO:0030242 pexophagy(GO:0030242)
0.1 0.4 GO:0042256 mature ribosome assembly(GO:0042256)
0.1 0.1 GO:0032650 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) interleukin-1 alpha secretion(GO:0050703)
0.1 0.2 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.1 0.3 GO:0042373 vitamin K metabolic process(GO:0042373)
0.1 3.5 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.1 0.5 GO:0032264 IMP salvage(GO:0032264)
0.1 1.6 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
0.1 0.3 GO:1990743 protein sialylation(GO:1990743)
0.1 0.4 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 1.4 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.1 0.4 GO:0015879 carnitine transport(GO:0015879)
0.1 0.7 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151)
0.1 0.5 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.2 GO:0006553 lysine metabolic process(GO:0006553)
0.1 0.2 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 0.6 GO:0046459 short-chain fatty acid metabolic process(GO:0046459)
0.1 0.3 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.1 0.3 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 1.0 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.1 0.7 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.1 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 0.2 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.1 0.2 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.1 0.2 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 0.3 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.1 0.2 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.1 0.6 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.1 0.1 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.1 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 0.6 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.1 0.2 GO:0002339 B cell selection(GO:0002339)
0.1 0.3 GO:0048266 behavioral response to pain(GO:0048266)
0.1 0.4 GO:1902741 type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.1 0.9 GO:0030574 collagen catabolic process(GO:0030574)
0.1 0.2 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.1 0.3 GO:0060290 transdifferentiation(GO:0060290)
0.1 2.6 GO:2001222 regulation of neuron migration(GO:2001222)
0.1 0.2 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.1 0.4 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.1 0.2 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.1 0.7 GO:0019363 pyridine nucleotide biosynthetic process(GO:0019363)
0.1 1.7 GO:0014047 glutamate secretion(GO:0014047)
0.1 0.1 GO:0001798 type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type I hypersensitivity(GO:0001812) type II hypersensitivity(GO:0002445) positive regulation of hypersensitivity(GO:0002885) regulation of type II hypersensitivity(GO:0002892) positive regulation of type II hypersensitivity(GO:0002894)
0.1 3.4 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1 0.4 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 1.7 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 0.8 GO:0046688 response to copper ion(GO:0046688)
0.1 0.5 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.3 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 0.3 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.1 0.5 GO:0035459 cargo loading into vesicle(GO:0035459) cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.2 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.1 1.2 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.5 GO:0007141 male meiosis I(GO:0007141)
0.0 0.5 GO:0060177 regulation of angiotensin metabolic process(GO:0060177)
0.0 2.3 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.6 GO:0008272 sulfate transport(GO:0008272)
0.0 0.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.2 GO:0006788 heme oxidation(GO:0006788)
0.0 0.5 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.1 GO:0003360 brainstem development(GO:0003360)
0.0 0.2 GO:0035608 protein deglutamylation(GO:0035608)
0.0 0.1 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0 0.8 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.8 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.0 0.1 GO:0000237 leptotene(GO:0000237)
0.0 0.2 GO:2000018 regulation of male gonad development(GO:2000018) positive regulation of male gonad development(GO:2000020) negative regulation of female gonad development(GO:2000195)
0.0 0.5 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 0.2 GO:0060690 epithelial cell differentiation involved in salivary gland development(GO:0060690)
0.0 0.5 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.2 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.1 GO:0072720 response to sorbitol(GO:0072708) response to dithiothreitol(GO:0072720)
0.0 0.1 GO:0048069 eye pigmentation(GO:0048069)
0.0 1.6 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.4 GO:1900194 receptor guanylyl cyclase signaling pathway(GO:0007168) negative regulation of oocyte maturation(GO:1900194)
0.0 0.2 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) myotome development(GO:0061055)
0.0 0.1 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.1 GO:0051866 general adaptation syndrome(GO:0051866)
0.0 0.2 GO:2000189 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.6 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.2 GO:0050912 detection of chemical stimulus involved in sensory perception(GO:0050907) detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
0.0 0.4 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 0.4 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.4 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.2 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.1 GO:0048820 hair follicle maturation(GO:0048820)
0.0 1.1 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.2 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 0.1 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.0 0.1 GO:0048296 negative regulation of isotype switching(GO:0045829) isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296)
0.0 0.4 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.1 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141) positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.3 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.0 0.9 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.1 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 0.5 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.0 0.1 GO:2001185 regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.0 0.1 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.0 0.2 GO:0045346 regulation of MHC class II biosynthetic process(GO:0045346) negative regulation of MHC class II biosynthetic process(GO:0045347) apoptotic process involved in patterning of blood vessels(GO:1902262)
0.0 0.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.0 0.1 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.1 GO:0019233 sensory perception of pain(GO:0019233)
0.0 1.8 GO:0007631 feeding behavior(GO:0007631)
0.0 0.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.2 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.3 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.3 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.1 GO:0031038 myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519)
0.0 0.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.1 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.1 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.1 GO:0060279 positive regulation of ovulation(GO:0060279)
0.0 0.7 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.2 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.1 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.6 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.3 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.3 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.1 GO:0009446 putrescine metabolic process(GO:0009445) putrescine biosynthetic process(GO:0009446)
0.0 0.3 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.5 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.5 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.2 GO:1900271 regulation of long-term synaptic potentiation(GO:1900271)
0.0 0.1 GO:0051023 regulation of immunoglobulin secretion(GO:0051023) positive regulation of immunoglobulin secretion(GO:0051024)
0.0 0.5 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.2 GO:0009650 UV protection(GO:0009650)
0.0 0.1 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.1 GO:0006014 D-ribose metabolic process(GO:0006014)
0.0 0.6 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.8 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.0 0.4 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 2.5 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0048703 embryonic viscerocranium morphogenesis(GO:0048703)
0.0 0.2 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.2 GO:0050892 intestinal absorption(GO:0050892)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.4 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.0 0.1 GO:1901072 glucosamine-containing compound catabolic process(GO:1901072)
0.0 0.1 GO:0030157 pancreatic juice secretion(GO:0030157)
0.0 0.1 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.0 0.6 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.1 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.0 0.1 GO:0044539 long-chain fatty acid import(GO:0044539)
0.0 0.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.5 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.5 GO:0007588 excretion(GO:0007588)
0.0 0.4 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.6 GO:0035411 catenin import into nucleus(GO:0035411)
0.0 0.1 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.0 0.1 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.0 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.0 0.6 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.0 0.1 GO:0010389 regulation of G2/M transition of mitotic cell cycle(GO:0010389) regulation of cell cycle G2/M phase transition(GO:1902749)
0.0 0.3 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.1 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.0 0.1 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.0 0.1 GO:0014823 response to activity(GO:0014823)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.1 GO:0032196 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) transposition(GO:0032196)
0.0 0.2 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.0 0.2 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.2 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.1 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.0 0.2 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.0 0.3 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0 0.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.5 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.1 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:0090282 positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931) positive regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0090282)
0.0 0.1 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.7 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.1 GO:1904690 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.0 0.2 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.2 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.1 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.0 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.0 0.1 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.5 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.3 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.9 GO:0032092 positive regulation of protein binding(GO:0032092)
0.0 0.1 GO:0036337 Fas signaling pathway(GO:0036337)
0.0 0.1 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 0.1 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.2 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.2 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.0 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.7 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.0 GO:0061153 hair follicle placode formation(GO:0060789) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.2 GO:0003341 cilium movement(GO:0003341)
0.0 0.1 GO:0006835 dicarboxylic acid transport(GO:0006835)
0.0 0.1 GO:0060632 regulation of microtubule-based movement(GO:0060632)
0.0 1.4 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.2 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.1 GO:0050821 protein stabilization(GO:0050821)
0.0 0.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.7 GO:1900006 positive regulation of dendrite development(GO:1900006)
0.0 0.2 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.1 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.4 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.0 GO:0042045 epithelial fluid transport(GO:0042045)
0.0 0.4 GO:0051693 actin filament capping(GO:0051693)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0071953 elastic fiber(GO:0071953)
0.3 1.0 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.3 1.3 GO:0097450 astrocyte end-foot(GO:0097450)
0.3 1.2 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.3 0.3 GO:0030120 vesicle coat(GO:0030120)
0.2 0.2 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.2 0.7 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 0.6 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.2 1.9 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.2 1.5 GO:0001739 sex chromatin(GO:0001739)
0.1 1.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 1.1 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 0.5 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.1 0.7 GO:1990130 Iml1 complex(GO:1990130)
0.1 1.0 GO:0005833 hemoglobin complex(GO:0005833)
0.1 0.6 GO:1990037 Lewy body core(GO:1990037)
0.1 0.4 GO:0070985 TFIIK complex(GO:0070985)
0.1 1.6 GO:0044327 dendritic spine head(GO:0044327)
0.1 0.5 GO:0097454 Schwann cell microvillus(GO:0097454)
0.1 3.4 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.1 0.9 GO:0097427 microtubule bundle(GO:0097427)
0.1 0.9 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 0.9 GO:0030478 actin cap(GO:0030478)
0.1 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.9 GO:0032982 myosin filament(GO:0032982)
0.1 0.6 GO:0005638 lamin filament(GO:0005638)
0.1 0.6 GO:0070695 FHF complex(GO:0070695)
0.1 0.7 GO:0001520 outer dense fiber(GO:0001520)
0.1 0.3 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 0.3 GO:0051286 cell tip(GO:0051286)
0.1 0.2 GO:0042642 actomyosin, myosin complex part(GO:0042642)
0.1 1.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.4 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.2 GO:0002142 stereocilia ankle link complex(GO:0002142)
0.1 0.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 2.5 GO:0030673 axolemma(GO:0030673)
0.1 0.3 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 1.7 GO:0030137 COPI-coated vesicle(GO:0030137)
0.1 0.5 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.7 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 0.2 GO:0031251 PAN complex(GO:0031251)
0.1 0.9 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.3 GO:0070876 SOSS complex(GO:0070876)
0.1 1.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 2.2 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.1 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 0.2 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.7 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.5 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.1 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.0 0.5 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.5 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.6 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 1.8 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.6 GO:0031528 microvillus membrane(GO:0031528)
0.0 6.5 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 1.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.5 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.7 GO:0043235 receptor complex(GO:0043235)
0.0 0.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.3 GO:0032806 carboxy-terminal domain protein kinase complex(GO:0032806)
0.0 1.7 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.3 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 1.9 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.2 GO:1990761 dendritic spine neck(GO:0044326) growth cone lamellipodium(GO:1990761)
0.0 0.4 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 1.4 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 2.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.5 GO:0042788 polysomal ribosome(GO:0042788)
0.0 1.6 GO:0031526 brush border membrane(GO:0031526)
0.0 0.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.1 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.5 GO:0010369 chromocenter(GO:0010369)
0.0 2.9 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.2 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 2.2 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.3 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.5 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.8 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.5 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.6 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304)
0.0 1.2 GO:0043679 axon terminus(GO:0043679)
0.0 0.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.2 GO:0030658 transport vesicle membrane(GO:0030658)
0.0 2.1 GO:0030027 lamellipodium(GO:0030027)
0.0 0.1 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 1.7 GO:0005814 centriole(GO:0005814)
0.0 0.2 GO:0032420 stereocilium(GO:0032420)
0.0 0.2 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.0 0.1 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.4 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 0.5 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.7 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.9 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.2 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.0 0.0 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 0.2 GO:0016459 myosin complex(GO:0016459)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.5 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.3 GO:0005921 gap junction(GO:0005921)
0.0 0.4 GO:0005795 Golgi stack(GO:0005795)
0.0 0.1 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.2 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.4 4.9 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.4 1.6 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.4 3.5 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.4 1.1 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.3 1.7 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.3 1.6 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.3 0.9 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.2 0.7 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.2 0.7 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.2 2.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.2 0.6 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.2 1.1 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.2 0.2 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.2 0.6 GO:0071723 lipopeptide binding(GO:0071723)
0.2 0.6 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.2 1.0 GO:0035240 dopamine binding(GO:0035240)
0.2 1.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.2 2.1 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.2 1.9 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.2 0.6 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.2 1.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.2 0.7 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.2 0.5 GO:0005118 sevenless binding(GO:0005118)
0.2 0.7 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.2 0.7 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.2 0.5 GO:0071633 dihydroceramidase activity(GO:0071633)
0.2 0.5 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.2 1.0 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.2 0.6 GO:0043546 molybdenum ion binding(GO:0030151) molybdopterin cofactor binding(GO:0043546)
0.2 0.9 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.2 4.0 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.2 0.5 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.2 3.2 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 1.9 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.4 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.6 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.1 0.4 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 1.6 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.4 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 0.4 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 0.5 GO:0050347 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.1 0.5 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.1 0.6 GO:0048495 Roundabout binding(GO:0048495)
0.1 1.0 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.5 GO:0004064 arylesterase activity(GO:0004064)
0.1 1.3 GO:0008227 G-protein coupled amine receptor activity(GO:0008227)
0.1 1.6 GO:0070300 phosphatidic acid binding(GO:0070300)
0.1 0.3 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.1 2.5 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.1 0.4 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.4 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1 0.3 GO:0005124 scavenger receptor binding(GO:0005124)
0.1 0.7 GO:0046790 virion binding(GO:0046790)
0.1 1.1 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.6 GO:0042731 PH domain binding(GO:0042731)
0.1 0.4 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 1.7 GO:0001848 complement binding(GO:0001848)
0.1 0.5 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 1.7 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.7 GO:0015087 cobalt ion transmembrane transporter activity(GO:0015087)
0.1 1.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 1.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 1.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 0.7 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 0.5 GO:0002054 nucleobase binding(GO:0002054)
0.1 0.5 GO:0033142 progesterone receptor binding(GO:0033142)
0.1 0.3 GO:0015254 glycerol channel activity(GO:0015254)
0.1 2.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 3.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.4 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.5 GO:0070728 leucine binding(GO:0070728)
0.1 0.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.8 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 1.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.4 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 1.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 1.8 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 0.5 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.3 GO:0004103 choline kinase activity(GO:0004103)
0.1 0.3 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.4 GO:0019864 immunoglobulin receptor activity(GO:0019763) IgG binding(GO:0019864)
0.1 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.2 GO:0097001 ceramide binding(GO:0097001)
0.1 0.4 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 0.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.2 GO:0008527 taste receptor activity(GO:0008527)
0.1 1.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 0.2 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1 0.4 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 0.9 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 1.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.5 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.1 0.9 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.1 0.4 GO:0004075 biotin carboxylase activity(GO:0004075)
0.1 3.1 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.1 0.7 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.8 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 5.8 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 0.2 GO:0004096 aminoacylase activity(GO:0004046) catalase activity(GO:0004096)
0.1 1.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.3 GO:0016803 ether hydrolase activity(GO:0016803)
0.1 0.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.1 GO:0022842 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.0 0.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.6 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.3 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.3 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.3 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 0.1 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 0.6 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.2 GO:0070573 tripeptidyl-peptidase activity(GO:0008240) metallodipeptidase activity(GO:0070573)
0.0 0.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.6 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 2.0 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.4 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 2.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.4 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.2 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.1 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 1.1 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.9 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.2 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.4 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.2 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.1 GO:0046977 TAP binding(GO:0046977) TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.3 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.9 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.7 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.1 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.5 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.0 0.7 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.8 GO:0035326 enhancer binding(GO:0035326)
0.0 0.7 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.1 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.1 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.0 1.0 GO:0051020 GTPase binding(GO:0051020)
0.0 0.2 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.3 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.1 GO:0031014 troponin T binding(GO:0031014)
0.0 1.5 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.7 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.2 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.3 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.2 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.7 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.2 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.3 GO:0051787 misfolded protein binding(GO:0051787)
0.0 5.3 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.0 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.0 0.2 GO:0030553 cGMP binding(GO:0030553)
0.0 0.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.0 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0042979 ornithine decarboxylase regulator activity(GO:0042979)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.1 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.3 GO:0005267 potassium channel activity(GO:0005267)
0.0 0.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.1 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.2 GO:0004540 ribonuclease activity(GO:0004540)
0.0 0.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.0 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0004407 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.0 2.5 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.2 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.1 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.0 0.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.2 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.4 GO:0017022 myosin binding(GO:0017022)
0.0 0.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0010181 FMN binding(GO:0010181)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.0 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.0 GO:0019211 phosphatase activator activity(GO:0019211)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.5 ST_STAT3_PATHWAY STAT3 Pathway
0.1 0.3 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.1 0.3 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.1 0.2 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 3.0 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.1 0.7 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 2.5 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.0 0.4 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 0.7 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 0.5 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.0 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.9 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 1.4 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.5 PID_ATR_PATHWAY ATR signaling pathway
0.0 4.4 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.2 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.7 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 0.4 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.0 0.1 ST_TYPE_I_INTERFERON_PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.2 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.5 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.5 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.0 0.2 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.0 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 1.5 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.7 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.2 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.0 1.1 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 0.4 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.3 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 0.9 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 0.9 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.4 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.2 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 0.2 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.0 2.0 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.0 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 0.1 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 0.2 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 0.4 PID_FGF_PATHWAY FGF signaling pathway
0.0 0.1 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.1 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.1 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.5 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 0.9 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 0.3 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 0.1 PID_FOXO_PATHWAY FoxO family signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.1 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.3 3.5 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.2 1.9 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.2 1.8 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.2 1.0 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 6.3 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 1.9 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 0.1 REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT Genes involved in Initial triggering of complement
0.1 1.8 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.6 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 0.8 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 1.3 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.5 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 3.7 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.1 2.1 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.1 2.2 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 0.8 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.1 0.5 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.1 2.6 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 0.8 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.1 2.3 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 0.4 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.1 0.7 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 1.7 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.1 0.6 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.1 0.4 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.9 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.5 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 1.7 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.9 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.3 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.0 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 1.0 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.8 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 1.1 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.5 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.8 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.7 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.6 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.0 0.4 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 1.4 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.3 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.6 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.6 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.1 REACTOME_ACYL_CHAIN_REMODELLING_OF_PS Genes involved in Acyl chain remodelling of PS
0.0 0.5 REACTOME_EARLY_PHASE_OF_HIV_LIFE_CYCLE Genes involved in Early Phase of HIV Life Cycle
0.0 0.2 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.5 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.0 0.4 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.1 REACTOME_ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.4 REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.5 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.3 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.4 REACTOME_RNA_POL_I_TRANSCRIPTION_INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 1.3 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.6 REACTOME_TRIGLYCERIDE_BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 0.1 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.6 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.2 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.2 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 1.9 REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 0.4 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.2 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.7 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.7 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.0 1.3 REACTOME_CELL_JUNCTION_ORGANIZATION Genes involved in Cell junction organization
0.0 0.2 REACTOME_RIG_I_MDA5_MEDIATED_INDUCTION_OF_IFN_ALPHA_BETA_PATHWAYS Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.0 0.1 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.2 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.2 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.4 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.3 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.2 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.5 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.1 REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.7 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.2 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.2 REACTOME_IRON_UPTAKE_AND_TRANSPORT Genes involved in Iron uptake and transport
0.0 0.2 REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.1 REACTOME_GAP_JUNCTION_TRAFFICKING Genes involved in Gap junction trafficking
0.0 0.1 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.1 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.2 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)