Motif ID: Gli1

Z-value: 0.688


Transcription factors associated with Gli1:

Gene SymbolEntrez IDGene Name
Gli1 ENSMUSG00000025407.6 Gli1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gli1mm10_v2_chr10_-_127341583_127341614-0.452.9e-03Click!


Activity profile for motif Gli1.

activity profile for motif Gli1


Sorted Z-values histogram for motif Gli1

Sorted Z-values for motif Gli1



Network of associatons between targets according to the STRING database.



First level regulatory network of Gli1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_78544345 2.498 ENSMUST00000053239.2
Sstr3
somatostatin receptor 3
chr11_-_119547744 2.321 ENSMUST00000026670.4
Nptx1
neuronal pentraxin 1
chr2_-_54085542 2.286 ENSMUST00000100089.2
Rprm
reprimo, TP53 dependent G2 arrest mediator candidate
chr13_-_114458720 1.914 ENSMUST00000022287.5
Fst
follistatin
chr14_+_25607797 1.907 ENSMUST00000160229.1
Zmiz1
zinc finger, MIZ-type containing 1
chr11_+_80300866 1.878 ENSMUST00000017836.7
Rhbdl3
rhomboid, veinlet-like 3 (Drosophila)
chr15_-_85581809 1.790 ENSMUST00000023015.7
Wnt7b
wingless-related MMTV integration site 7B
chr18_-_43373248 1.564 ENSMUST00000118043.1
Dpysl3
dihydropyrimidinase-like 3
chr15_-_95528228 1.559 ENSMUST00000075275.2
Nell2
NEL-like 2
chr6_-_52012476 1.477 ENSMUST00000078214.5
Skap2
src family associated phosphoprotein 2
chr10_-_64090265 1.434 ENSMUST00000105439.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr8_+_45658273 1.421 ENSMUST00000153798.1
Sorbs2
sorbin and SH3 domain containing 2
chr10_-_64090241 1.419 ENSMUST00000133588.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr1_-_133801031 1.377 ENSMUST00000143567.1
Atp2b4
ATPase, Ca++ transporting, plasma membrane 4
chr12_+_44328882 1.317 ENSMUST00000020939.8
ENSMUST00000110748.2
Nrcam

neuron-glia-CAM-related cell adhesion molecule

chr9_+_50752758 1.291 ENSMUST00000034562.7
Cryab
crystallin, alpha B
chr12_-_81333129 1.230 ENSMUST00000085238.6
ENSMUST00000182208.1
Slc8a3

solute carrier family 8 (sodium/calcium exchanger), member 3

chr15_-_95528702 1.228 ENSMUST00000166170.1
Nell2
NEL-like 2
chr1_-_64121389 1.202 ENSMUST00000055001.3
Klf7
Kruppel-like factor 7 (ubiquitous)
chrX_+_159303266 1.179 ENSMUST00000112491.1
Rps6ka3
ribosomal protein S6 kinase polypeptide 3
chr8_+_54954728 1.133 ENSMUST00000033915.7
Gpm6a
glycoprotein m6a
chr9_+_45954101 1.129 ENSMUST00000181487.1
A830035O19Rik
RIKEN cDNA A830035O19 gene
chr10_+_69534039 1.064 ENSMUST00000182557.1
Ank3
ankyrin 3, epithelial
chr10_+_69534208 1.047 ENSMUST00000182439.1
ENSMUST00000092434.5
ENSMUST00000092432.5
ENSMUST00000092431.5
ENSMUST00000054167.8
ENSMUST00000047061.6
Ank3





ankyrin 3, epithelial





chr8_+_45658731 1.000 ENSMUST00000143820.1
ENSMUST00000132139.1
Sorbs2

sorbin and SH3 domain containing 2

chr1_+_72824482 0.992 ENSMUST00000047328.4
Igfbp2
insulin-like growth factor binding protein 2
chr2_-_59948155 0.991 ENSMUST00000153136.1
Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr8_+_45658666 0.979 ENSMUST00000134675.1
ENSMUST00000139869.1
ENSMUST00000126067.1
Sorbs2


sorbin and SH3 domain containing 2


chr2_+_129800451 0.941 ENSMUST00000165413.2
ENSMUST00000166282.2
Stk35

serine/threonine kinase 35

chrX_-_60893430 0.921 ENSMUST00000135107.2
Sox3
SRY-box containing gene 3
chr4_-_68954351 0.876 ENSMUST00000030036.5
Brinp1
bone morphogenic protein/retinoic acid inducible neural specific 1
chr2_+_119351222 0.874 ENSMUST00000028780.3
Chac1
ChaC, cation transport regulator 1
chr13_+_109685994 0.852 ENSMUST00000074103.5
Pde4d
phosphodiesterase 4D, cAMP specific
chr10_+_69533803 0.830 ENSMUST00000182155.1
ENSMUST00000183169.1
ENSMUST00000183148.1
Ank3


ankyrin 3, epithelial


chr4_+_106561027 0.784 ENSMUST00000047973.3
Dhcr24
24-dehydrocholesterol reductase
chrX_+_101299143 0.763 ENSMUST00000118111.1
ENSMUST00000130555.1
ENSMUST00000151528.1
Nlgn3


neuroligin 3


chr8_-_41016749 0.753 ENSMUST00000117735.1
Mtus1
mitochondrial tumor suppressor 1
chr13_+_44729535 0.730 ENSMUST00000174068.1
Jarid2
jumonji, AT rich interactive domain 2
chr1_+_129273344 0.707 ENSMUST00000073527.6
ENSMUST00000040311.7
Thsd7b

thrombospondin, type I, domain containing 7B

chr4_+_117096049 0.701 ENSMUST00000030443.5
Ptch2
patched homolog 2
chr1_-_191907527 0.692 ENSMUST00000069573.5
1700034H15Rik
RIKEN cDNA 1700034H15 gene
chr1_+_152954966 0.685 ENSMUST00000043313.8
Nmnat2
nicotinamide nucleotide adenylyltransferase 2
chr1_-_25228814 0.674 ENSMUST00000126626.1
Bai3
brain-specific angiogenesis inhibitor 3
chr16_-_91011029 0.667 ENSMUST00000130813.1
Synj1
synaptojanin 1
chrX_-_59567348 0.660 ENSMUST00000124402.1
Fgf13
fibroblast growth factor 13
chr2_+_20737306 0.656 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4

enhancer trap locus 4

chr2_-_92434027 0.642 ENSMUST00000111278.1
ENSMUST00000090559.5
Cry2

cryptochrome 2 (photolyase-like)

chr9_+_104063678 0.632 ENSMUST00000047799.5
Acad11
acyl-Coenzyme A dehydrogenase family, member 11
chr5_+_30588078 0.625 ENSMUST00000066295.2
Kcnk3
potassium channel, subfamily K, member 3
chr5_+_5573952 0.621 ENSMUST00000101627.2
Gm8773
predicted gene 8773
chr6_-_41636389 0.617 ENSMUST00000031902.5
Trpv6
transient receptor potential cation channel, subfamily V, member 6
chr2_-_151973840 0.614 ENSMUST00000109865.1
ENSMUST00000109864.1
Fam110a

family with sequence similarity 110, member A

chr8_-_41016295 0.610 ENSMUST00000131965.1
Mtus1
mitochondrial tumor suppressor 1
chr2_+_157560078 0.606 ENSMUST00000153739.2
ENSMUST00000173595.1
ENSMUST00000109526.1
ENSMUST00000173839.1
ENSMUST00000173041.1
ENSMUST00000173793.1
ENSMUST00000172487.1
ENSMUST00000088484.5
Nnat







neuronatin







chr2_+_120629113 0.604 ENSMUST00000150912.1
ENSMUST00000180041.1
Stard9

START domain containing 9

chr17_-_24209377 0.601 ENSMUST00000024931.4
Ntn3
netrin 3
chr8_-_41041828 0.601 ENSMUST00000051379.7
Mtus1
mitochondrial tumor suppressor 1
chr3_+_45378396 0.599 ENSMUST00000166126.1
ENSMUST00000170695.1
ENSMUST00000171554.1
Pcdh10


protocadherin 10


chr6_-_28830345 0.596 ENSMUST00000171353.1
Lrrc4
leucine rich repeat containing 4
chrX_+_155262443 0.583 ENSMUST00000026324.9
Acot9
acyl-CoA thioesterase 9
chr7_-_80340152 0.568 ENSMUST00000133728.1
Unc45a
unc-45 homolog A (C. elegans)
chr2_+_29890534 0.557 ENSMUST00000113764.3
Odf2
outer dense fiber of sperm tails 2
chr2_+_181520533 0.544 ENSMUST00000108797.1
Dnajc5
DnaJ (Hsp40) homolog, subfamily C, member 5
chr1_-_56972437 0.540 ENSMUST00000042857.7
Satb2
special AT-rich sequence binding protein 2
chr3_+_68494208 0.538 ENSMUST00000182719.1
Schip1
schwannomin interacting protein 1
chr13_+_54575008 0.536 ENSMUST00000026988.4
Arl10
ADP-ribosylation factor-like 10
chr2_-_103797617 0.525 ENSMUST00000028607.6
Caprin1
cell cycle associated protein 1
chr15_-_100584075 0.515 ENSMUST00000184908.1
POU6F1
POU domain, class 6, transcription factor 1 (Pou6f1), mRNA
chr2_+_119034783 0.504 ENSMUST00000028796.1
Rpusd2
RNA pseudouridylate synthase domain containing 2
chr13_+_54575020 0.503 ENSMUST00000156024.1
Arl10
ADP-ribosylation factor-like 10
chr2_-_93046053 0.501 ENSMUST00000111272.1
ENSMUST00000178666.1
ENSMUST00000147339.1
Prdm11


PR domain containing 11


chr2_+_29890063 0.492 ENSMUST00000028128.6
Odf2
outer dense fiber of sperm tails 2
chr4_-_58553311 0.491 ENSMUST00000107571.1
ENSMUST00000055018.4
Lpar1

lysophosphatidic acid receptor 1

chr4_-_58553184 0.487 ENSMUST00000145361.1
Lpar1
lysophosphatidic acid receptor 1
chr4_-_58553553 0.483 ENSMUST00000107575.2
ENSMUST00000107574.1
ENSMUST00000147354.1
Lpar1


lysophosphatidic acid receptor 1


chr8_-_64733534 0.470 ENSMUST00000141021.1
Sc4mol
sterol-C4-methyl oxidase-like
chr19_+_55316313 0.466 ENSMUST00000095950.2
Vti1a
vesicle transport through interaction with t-SNAREs 1A
chr2_+_29889720 0.465 ENSMUST00000113767.1
Odf2
outer dense fiber of sperm tails 2
chr5_-_115436508 0.461 ENSMUST00000078701.3
4930430O22Rik
RIKEN cDNA 4930430O22 gene
chr14_+_60378242 0.459 ENSMUST00000022561.6
Amer2
APC membrane recruitment 2
chr8_-_72213636 0.454 ENSMUST00000109987.1
Gm11034
predicted gene 11034
chr2_-_104493690 0.452 ENSMUST00000111124.1
Hipk3
homeodomain interacting protein kinase 3
chr13_-_58385190 0.449 ENSMUST00000022032.5
2210016F16Rik
RIKEN cDNA 2210016F16 gene
chrX_+_101299207 0.446 ENSMUST00000065858.2
Nlgn3
neuroligin 3
chrX_+_94234594 0.445 ENSMUST00000153900.1
Klhl15
kelch-like 15
chr4_-_41275091 0.445 ENSMUST00000030143.6
ENSMUST00000108068.1
Ubap2

ubiquitin-associated protein 2

chr4_+_11156411 0.442 ENSMUST00000029865.3
Trp53inp1
transformation related protein 53 inducible nuclear protein 1
chr4_-_148130678 0.438 ENSMUST00000030862.4
Draxin
dorsal inhibitory axon guidance protein
chr17_+_37045963 0.436 ENSMUST00000025338.9
Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr7_+_28180272 0.411 ENSMUST00000173223.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr7_+_28180226 0.400 ENSMUST00000172467.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr2_-_29253001 0.396 ENSMUST00000071201.4
Ntng2
netrin G2
chr17_-_57031468 0.392 ENSMUST00000007814.8
Khsrp
KH-type splicing regulatory protein
chr6_-_113531575 0.391 ENSMUST00000032425.5
Emc3
ER membrane protein complex subunit 3
chr1_+_153900572 0.391 ENSMUST00000139476.1
Glul
glutamate-ammonia ligase (glutamine synthetase)
chr17_+_34187545 0.389 ENSMUST00000170086.1
Tap1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr2_+_29890096 0.383 ENSMUST00000113762.1
ENSMUST00000113765.1
Odf2

outer dense fiber of sperm tails 2

chr2_-_152830615 0.369 ENSMUST00000146380.1
ENSMUST00000134902.1
ENSMUST00000134357.1
ENSMUST00000109820.3
Bcl2l1



BCL2-like 1



chr6_+_108213086 0.367 ENSMUST00000032192.6
Itpr1
inositol 1,4,5-trisphosphate receptor 1
chr7_+_141216626 0.367 ENSMUST00000141804.1
ENSMUST00000148975.1
Rassf7

Ras association (RalGDS/AF-6) domain family (N-terminal) member 7

chr5_-_115300957 0.363 ENSMUST00000009157.3
Dynll1
dynein light chain LC8-type 1
chr5_-_122989260 0.360 ENSMUST00000118027.1
Kdm2b
lysine (K)-specific demethylase 2B
chr5_-_122989086 0.359 ENSMUST00000046073.9
Kdm2b
lysine (K)-specific demethylase 2B
chr5_-_115300912 0.354 ENSMUST00000112090.1
Dynll1
dynein light chain LC8-type 1
chr11_+_97840780 0.342 ENSMUST00000054783.4
B230217C12Rik
RIKEN cDNA B230217C12 gene
chr17_+_56326045 0.342 ENSMUST00000139679.1
ENSMUST00000025036.4
ENSMUST00000086835.5
Kdm4b


lysine (K)-specific demethylase 4B


chr2_+_118111876 0.341 ENSMUST00000039559.8
Thbs1
thrombospondin 1
chr18_+_37355271 0.335 ENSMUST00000051163.1
Pcdhb8
protocadherin beta 8
chr1_-_64121456 0.330 ENSMUST00000142009.1
ENSMUST00000114086.1
Klf7

Kruppel-like factor 7 (ubiquitous)

chr6_-_148944750 0.327 ENSMUST00000111562.1
ENSMUST00000081956.5
Fam60a

family with sequence similarity 60, member A

chr5_-_122900267 0.325 ENSMUST00000031435.7
Kdm2b
lysine (K)-specific demethylase 2B
chr11_-_78245942 0.325 ENSMUST00000002121.4
Supt6
suppressor of Ty 6
chr5_-_32746317 0.315 ENSMUST00000135248.1
Pisd
phosphatidylserine decarboxylase
chr2_+_29889785 0.312 ENSMUST00000113763.1
ENSMUST00000113757.1
ENSMUST00000113756.1
ENSMUST00000133233.1
ENSMUST00000113759.2
ENSMUST00000113755.1
ENSMUST00000137558.1
ENSMUST00000046571.7
Odf2







outer dense fiber of sperm tails 2







chr4_-_133874682 0.304 ENSMUST00000168974.2
Rps6ka1
ribosomal protein S6 kinase polypeptide 1
chr11_+_77763246 0.303 ENSMUST00000108375.2
Myo18a
myosin XVIIIA
chr11_+_70214105 0.298 ENSMUST00000094055.3
ENSMUST00000136328.1
ENSMUST00000126296.1
ENSMUST00000153993.2
Slc16a11



solute carrier family 16 (monocarboxylic acid transporters), member 11



chr2_+_181520485 0.297 ENSMUST00000072334.5
Dnajc5
DnaJ (Hsp40) homolog, subfamily C, member 5
chr11_-_98149551 0.291 ENSMUST00000103143.3
Fbxl20
F-box and leucine-rich repeat protein 20
chr13_-_53377355 0.261 ENSMUST00000021920.6
Sptlc1
serine palmitoyltransferase, long chain base subunit 1
chr5_-_134456227 0.253 ENSMUST00000111244.1
Gtf2ird1
general transcription factor II I repeat domain-containing 1
chr4_+_139193996 0.251 ENSMUST00000030518.9
Capzb
capping protein (actin filament) muscle Z-line, beta
chr5_-_146963742 0.251 ENSMUST00000125217.1
ENSMUST00000110564.1
ENSMUST00000066675.3
ENSMUST00000016654.2
ENSMUST00000110566.1
ENSMUST00000140526.1
Mtif3





mitochondrial translational initiation factor 3





chr4_+_133011506 0.251 ENSMUST00000105915.1
ENSMUST00000105916.1
Ahdc1

AT hook, DNA binding motif, containing 1

chr6_+_28423539 0.248 ENSMUST00000020717.5
ENSMUST00000169841.1
Arf5

ADP-ribosylation factor 5

chr14_-_54409469 0.247 ENSMUST00000000984.4
Slc7a7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr11_-_96824008 0.241 ENSMUST00000142065.1
ENSMUST00000167110.1
ENSMUST00000169828.1
ENSMUST00000126949.1
Nfe2l1



nuclear factor, erythroid derived 2,-like 1



chr9_-_110117379 0.237 ENSMUST00000111991.2
ENSMUST00000149199.1
ENSMUST00000035056.7
ENSMUST00000148287.1
ENSMUST00000127744.1
Dhx30




DEAH (Asp-Glu-Ala-His) box polypeptide 30




chr10_+_40883819 0.236 ENSMUST00000105509.1
Wasf1
WAS protein family, member 1
chr17_+_34187789 0.231 ENSMUST00000041633.8
Tap1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr14_+_55560480 0.206 ENSMUST00000121622.1
ENSMUST00000143431.1
ENSMUST00000150481.1
Dcaf11


DDB1 and CUL4 associated factor 11


chr15_+_99392948 0.205 ENSMUST00000161250.1
ENSMUST00000160635.1
ENSMUST00000161778.1
Tmbim6


transmembrane BAX inhibitor motif containing 6


chr4_-_43454600 0.196 ENSMUST00000098105.3
ENSMUST00000098104.3
ENSMUST00000030179.4
Cd72


CD72 antigen


chr4_-_16163611 0.195 ENSMUST00000037035.5
Ripk2
receptor (TNFRSF)-interacting serine-threonine kinase 2
chr13_+_118714678 0.191 ENSMUST00000022246.8
Fgf10
fibroblast growth factor 10
chr2_+_76369967 0.183 ENSMUST00000046389.4
Rbm45
RNA binding motif protein 45
chr6_+_95117740 0.172 ENSMUST00000032107.7
ENSMUST00000119582.1
Kbtbd8

kelch repeat and BTB (POZ) domain containing 8

chr4_+_123233556 0.171 ENSMUST00000040821.4
Heyl
hairy/enhancer-of-split related with YRPW motif-like
chr17_-_84790517 0.163 ENSMUST00000112308.2
Lrpprc
leucine-rich PPR-motif containing
chr13_+_5861489 0.157 ENSMUST00000000080.6
Klf6
Kruppel-like factor 6
chr14_+_55560904 0.151 ENSMUST00000072530.4
ENSMUST00000128490.1
Dcaf11

DDB1 and CUL4 associated factor 11

chrX_-_140956675 0.144 ENSMUST00000033805.8
ENSMUST00000112978.1
Psmd10

proteasome (prosome, macropain) 26S subunit, non-ATPase, 10

chr4_+_74251928 0.143 ENSMUST00000030102.5
Kdm4c
lysine (K)-specific demethylase 4C
chr6_+_37870786 0.138 ENSMUST00000120428.1
ENSMUST00000031859.7
Trim24

tripartite motif-containing 24

chr16_-_90284412 0.133 ENSMUST00000039280.7
Scaf4
SR-related CTD-associated factor 4
chr11_+_85311232 0.126 ENSMUST00000020835.9
Ppm1d
protein phosphatase 1D magnesium-dependent, delta isoform
chr11_-_42000532 0.121 ENSMUST00000070735.3
Gabrg2
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr2_+_85037448 0.118 ENSMUST00000168266.1
ENSMUST00000130729.1
Ssrp1

structure specific recognition protein 1

chr13_+_6548154 0.112 ENSMUST00000021611.8
Pitrm1
pitrilysin metallepetidase 1
chr11_-_61494173 0.110 ENSMUST00000101085.2
ENSMUST00000079080.6
ENSMUST00000108714.1
Mapk7


mitogen-activated protein kinase 7


chr18_+_37477768 0.103 ENSMUST00000051442.5
Pcdhb16
protocadherin beta 16
chr4_+_40948401 0.086 ENSMUST00000030128.5
Chmp5
charged multivesicular body protein 5
chr17_-_89910449 0.085 ENSMUST00000086423.4
Gm10184
predicted pseudogene 10184
chr4_-_40948196 0.085 ENSMUST00000030125.4
ENSMUST00000108089.1
Bag1

BCL2-associated athanogene 1

chr6_+_113531675 0.082 ENSMUST00000036340.5
ENSMUST00000101051.2
Fancd2

Fanconi anemia, complementation group D2

chr4_-_43454563 0.081 ENSMUST00000107926.1
Cd72
CD72 antigen
chr4_-_43454582 0.073 ENSMUST00000107925.1
Cd72
CD72 antigen
chr2_+_85037212 0.072 ENSMUST00000077798.6
Ssrp1
structure specific recognition protein 1
chr19_-_3575708 0.064 ENSMUST00000113997.2
ENSMUST00000025846.8
ENSMUST00000172362.1
Ppp6r3


protein phosphatase 6, regulatory subunit 3


chr19_-_6084679 0.064 ENSMUST00000161548.1
Zfpl1
zinc finger like protein 1
chr2_-_152831112 0.062 ENSMUST00000128172.1
Bcl2l1
BCL2-like 1
chr4_-_155863362 0.061 ENSMUST00000030949.3
Tas1r3
taste receptor, type 1, member 3
chr7_+_80186835 0.060 ENSMUST00000107383.1
ENSMUST00000032754.7
Sema4b

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B

chr14_+_55561060 0.051 ENSMUST00000117701.1
Dcaf11
DDB1 and CUL4 associated factor 11
chr14_-_41008256 0.050 ENSMUST00000136661.1
Fam213a
family with sequence similarity 213, member A
chr18_-_35662180 0.049 ENSMUST00000025209.4
ENSMUST00000096573.2
Spata24

spermatogenesis associated 24

chr3_+_88553716 0.041 ENSMUST00000008748.6
Ubqln4
ubiquilin 4
chr12_+_24498570 0.039 ENSMUST00000075954.7
Taf1b
TATA box binding protein (Tbp)-associated factor, RNA polymerase I, B
chr2_+_181497223 0.038 ENSMUST00000108799.3
Tpd52l2
tumor protein D52-like 2
chr2_+_23069210 0.033 ENSMUST00000155602.1
Acbd5
acyl-Coenzyme A binding domain containing 5
chr10_+_69533761 0.031 ENSMUST00000182884.1
Ank3
ankyrin 3, epithelial
chr2_+_15055274 0.029 ENSMUST00000069870.3
Arl5b
ADP-ribosylation factor-like 5B
chr12_-_112673944 0.022 ENSMUST00000130342.1
Akt1
thymoma viral proto-oncogene 1
chr16_-_56024628 0.016 ENSMUST00000119981.1
ENSMUST00000096021.3
Pcnp

PEST proteolytic signal containing nuclear protein

chr7_-_6331235 0.015 ENSMUST00000127658.1
ENSMUST00000062765.7
Zfp583

zinc finger protein 583

chr7_+_44849949 0.014 ENSMUST00000141311.1
ENSMUST00000107880.1
Akt1s1

AKT1 substrate 1 (proline-rich)

chr5_-_110779937 0.014 ENSMUST00000112426.1
Pus1
pseudouridine synthase 1
chr2_+_164879358 0.011 ENSMUST00000041643.3
Pcif1
PDX1 C-terminal inhibiting factor 1
chr8_+_13757663 0.011 ENSMUST00000043962.8
Cdc16
CDC16 cell division cycle 16
chr2_-_121456693 0.005 ENSMUST00000110613.2
ENSMUST00000056312.3
Serinc4

serine incorporator 4

chr11_-_45955183 0.000 ENSMUST00000109254.1
Thg1l
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.6 1.7 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.5 2.3 GO:0035864 response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.4 1.2 GO:2000331 regulation of terminal button organization(GO:2000331)
0.4 1.5 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.3 1.9 GO:0007296 vitellogenesis(GO:0007296)
0.3 3.0 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.3 1.8 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.3 2.8 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.2 0.2 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.2 1.9 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.2 1.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.2 0.9 GO:0006751 glutathione catabolic process(GO:0006751)
0.2 1.3 GO:0007021 tubulin complex assembly(GO:0007021)
0.2 0.6 GO:2000850 protein-chromophore linkage(GO:0018298) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.2 1.0 GO:0021993 initiation of neural tube closure(GO:0021993)
0.2 0.6 GO:1904978 regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980)
0.2 2.9 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.2 0.7 GO:0009957 epidermal cell fate specification(GO:0009957)
0.2 0.7 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.2 0.6 GO:0046967 cytosol to ER transport(GO:0046967)
0.1 0.4 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.1 0.4 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.1 0.4 GO:0046898 response to cycloheximide(GO:0046898)
0.1 0.8 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 0.3 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 1.1 GO:0045019 negative regulation of nitric oxide biosynthetic process(GO:0045019) negative regulation of nitric oxide metabolic process(GO:1904406)
0.1 0.6 GO:0098909 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.1 0.3 GO:1903028 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.1 2.0 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.1 0.4 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.1 3.4 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.3 GO:0002209 behavioral fear response(GO:0001662) behavioral defense response(GO:0002209) fear response(GO:0042596)
0.1 0.7 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.9 GO:1901898 regulation of cell communication by electrical coupling(GO:0010649) regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.8 GO:0031639 plasminogen activation(GO:0031639)
0.1 1.6 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.2 GO:0070671 response to interleukin-12(GO:0070671)
0.1 0.3 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 0.2 GO:0071336 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.1 2.5 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.1 0.9 GO:0042711 maternal behavior(GO:0042711)
0.1 0.3 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.4 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.5 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.2 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 1.0 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.0 0.9 GO:0007530 sex determination(GO:0007530)
0.0 0.3 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.6 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0 0.2 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.6 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.0 0.2 GO:0032811 regulation of epinephrine secretion(GO:0014060) negative regulation of epinephrine secretion(GO:0032811)
0.0 1.4 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.3 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.2 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.1 GO:0070375 ERK5 cascade(GO:0070375)
0.0 0.5 GO:0001553 luteinization(GO:0001553)
0.0 0.3 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.6 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.2 GO:0072014 proximal tubule development(GO:0072014)
0.0 0.2 GO:1990416 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.5 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.1 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.1 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.4 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.2 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.0 1.1 GO:0003407 neural retina development(GO:0003407)
0.0 0.2 GO:0014029 neural crest formation(GO:0014029)
0.0 0.1 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 1.2 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 1.2 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.0 2.3 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.5 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.0 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.1 GO:0050912 detection of chemical stimulus involved in sensory perception(GO:0050907) detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
0.0 0.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.6 GO:0007517 muscle organ development(GO:0007517)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0097512 cardiac myofibril(GO:0097512)
0.1 3.0 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 2.2 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 0.4 GO:0031088 platelet dense granule membrane(GO:0031088) platelet dense tubular network(GO:0031094)
0.1 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.6 GO:0042825 TAP complex(GO:0042825)
0.1 1.4 GO:0097228 sperm principal piece(GO:0097228)
0.1 0.3 GO:0035339 SPOTS complex(GO:0035339)
0.1 1.3 GO:0043194 axon initial segment(GO:0043194)
0.1 2.6 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.2 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.7 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.3 GO:0071203 WASH complex(GO:0071203)
0.0 0.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.6 GO:0031941 filamentous actin(GO:0031941)
0.0 0.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.6 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 0.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.5 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 1.0 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 2.9 GO:0043204 perikaryon(GO:0043204)
0.0 1.1 GO:0044295 axonal growth cone(GO:0044295)
0.0 2.7 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.3 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 1.2 GO:0031594 neuromuscular junction(GO:0031594)
0.0 2.3 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.0 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.6 GO:0005871 kinesin complex(GO:0005871)
0.0 0.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.8 GO:0043195 terminal bouton(GO:0043195)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0004994 somatostatin receptor activity(GO:0004994)
0.4 1.8 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.3 1.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.2 0.7 GO:0005119 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158)
0.2 0.6 GO:0009881 photoreceptor activity(GO:0009881)
0.2 0.6 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.2 1.5 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.2 0.6 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.2 0.9 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.2 1.9 GO:0048185 activin binding(GO:0048185)
0.2 1.6 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 0.7 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.2 0.6 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.1 1.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.4 GO:0016880 acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 2.1 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.1 1.0 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.4 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.6 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1 0.3 GO:0070052 collagen V binding(GO:0070052)
0.1 0.3 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 1.5 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.3 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.1 1.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 5.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.6 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.2 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.4 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.2 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.8 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 1.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 1.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.3 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 2.8 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.8 GO:0042605 peptide antigen binding(GO:0042605)
0.0 3.4 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.2 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.7 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 1.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 1.8 GO:0005262 calcium channel activity(GO:0005262)
0.0 1.0 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.2 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.8 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.6 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.5 GO:0005484 SNAP receptor activity(GO:0005484)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 1.5 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.6 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 1.7 PID_BMP_PATHWAY BMP receptor signaling
0.0 4.5 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.8 PID_PLK1_PATHWAY PLK1 signaling events
0.0 0.7 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 2.0 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 0.4 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.5 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.0 0.4 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.6 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.0 0.6 PID_EPHB_FWD_PATHWAY EPHB forward signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.3 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.2 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 1.5 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 0.6 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 1.6 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.0 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.6 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.0 0.8 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.6 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.4 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.0 4.0 REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 0.4 REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.7 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.0 2.4 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.9 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.3 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.6 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.6 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.2 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.4 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.6 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.2 REACTOME_P75NTR_RECRUITS_SIGNALLING_COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.1 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway