Motif ID: Rfx3_Rfx1_Rfx4

Z-value: 2.661

Transcription factors associated with Rfx3_Rfx1_Rfx4:

Gene SymbolEntrez IDGene Name
Rfx1 ENSMUSG00000031706.6 Rfx1
Rfx3 ENSMUSG00000040929.10 Rfx3
Rfx4 ENSMUSG00000020037.9 Rfx4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rfx1mm10_v2_chr8_+_84066824_84066882-0.324.1e-02Click!
Rfx4mm10_v2_chr10_+_84838143_84838153-0.314.6e-02Click!
Rfx3mm10_v2_chr19_-_28010995_280110540.048.2e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Rfx3_Rfx1_Rfx4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_+_60925612 32.716 ENSMUST00000102888.3
ENSMUST00000025519.4
Camk2a

calcium/calmodulin-dependent protein kinase II alpha

chr15_+_98167806 19.919 ENSMUST00000031914.4
AI836003
expressed sequence AI836003
chr7_-_31051431 18.797 ENSMUST00000073892.4
Fxyd7
FXYD domain-containing ion transport regulator 7
chr18_+_60925644 15.128 ENSMUST00000115297.1
Camk2a
calcium/calmodulin-dependent protein kinase II alpha
chr5_+_120431770 12.887 ENSMUST00000031591.7
Lhx5
LIM homeobox protein 5
chrX_+_7919816 12.788 ENSMUST00000041096.3
Pcsk1n
proprotein convertase subtilisin/kexin type 1 inhibitor
chr4_-_119415494 12.185 ENSMUST00000063642.2
Ccdc30
coiled-coil domain containing 30
chr5_+_24985840 10.671 ENSMUST00000075081.6
1500035N22Rik
RIKEN cDNA 1500035N22 gene
chr7_-_140082246 10.486 ENSMUST00000166758.2
Caly
calcyon neuron-specific vesicular protein
chr2_+_121289589 10.418 ENSMUST00000094639.3
Map1a
microtubule-associated protein 1 A
chr11_-_105944412 10.189 ENSMUST00000019734.4
ENSMUST00000184269.1
ENSMUST00000150563.1
Cyb561


cytochrome b-561


chr7_-_140082489 9.766 ENSMUST00000026541.7
Caly
calcyon neuron-specific vesicular protein
chr16_+_14906622 9.762 ENSMUST00000090277.1
Efcab1
EF hand calcium binding domain 1
chr7_+_99268338 9.348 ENSMUST00000107100.2
Map6
microtubule-associated protein 6
chr17_+_34629533 9.076 ENSMUST00000015620.6
Prrt1
proline-rich transmembrane protein 1
chr17_-_31277327 8.167 ENSMUST00000024832.7
Rsph1
radial spoke head 1 homolog (Chlamydomonas)
chr11_-_105944128 8.148 ENSMUST00000184086.1
Cyb561
cytochrome b-561
chr2_-_118256929 7.538 ENSMUST00000028820.6
ENSMUST00000028821.3
Fsip1

fibrous sheath-interacting protein 1

chr16_-_16829276 7.421 ENSMUST00000023468.5
Spag6
sperm associated antigen 6
chr11_-_6606053 7.144 ENSMUST00000045713.3
Nacad
NAC alpha domain containing
chr19_+_47178820 7.110 ENSMUST00000111808.3
Neurl1a
neuralized homolog 1A (Drosophila)
chr1_+_66386968 7.020 ENSMUST00000145419.1
Map2
microtubule-associated protein 2
chr11_-_116335384 6.963 ENSMUST00000036215.7
Foxj1
forkhead box J1
chr9_+_59589288 6.839 ENSMUST00000121266.1
ENSMUST00000118164.1
Celf6

CUGBP, Elav-like family member 6

chr7_+_131966446 6.792 ENSMUST00000045840.4
Gpr26
G protein-coupled receptor 26
chr3_-_88458876 6.679 ENSMUST00000147200.1
ENSMUST00000169222.1
Sema4a

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A

chr6_+_56017489 6.588 ENSMUST00000052827.4
Ppp1r17
protein phosphatase 1, regulatory subunit 17
chr3_-_88459047 6.358 ENSMUST00000165898.1
ENSMUST00000127436.1
Sema4a

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A

chr13_+_24845122 6.309 ENSMUST00000006893.8
D130043K22Rik
RIKEN cDNA D130043K22 gene
chr4_-_153482768 6.239 ENSMUST00000105646.2
Ajap1
adherens junction associated protein 1
chr10_-_81472859 6.162 ENSMUST00000147524.1
ENSMUST00000119060.1
Celf5

CUGBP, Elav-like family member 5

chr12_-_84148449 5.919 ENSMUST00000061425.2
Pnma1
paraneoplastic antigen MA1
chr7_+_16959714 5.875 ENSMUST00000038163.6
Pnmal1
PNMA-like 1
chr1_+_172521044 5.784 ENSMUST00000085894.5
ENSMUST00000161140.1
ENSMUST00000162988.1
Ccdc19


coiled-coil domain containing 19


chr14_-_8309770 5.707 ENSMUST00000121887.1
ENSMUST00000036070.8
ENSMUST00000137133.1
Fam107a


family with sequence similarity 107, member A


chr7_+_16944645 5.508 ENSMUST00000094807.5
Pnmal2
PNMA-like 2
chr15_+_89532816 5.391 ENSMUST00000167173.1
Shank3
SH3/ankyrin domain gene 3
chr1_-_84696182 5.091 ENSMUST00000049126.6
Dner
delta/notch-like EGF-related receptor
chr7_-_4546567 5.085 ENSMUST00000065957.5
Syt5
synaptotagmin V
chr17_+_27685197 5.022 ENSMUST00000097360.2
Pacsin1
protein kinase C and casein kinase substrate in neurons 1
chr1_-_60043087 4.956 ENSMUST00000027172.6
Ica1l
islet cell autoantigen 1-like
chr8_-_95142477 4.859 ENSMUST00000034240.7
ENSMUST00000169748.1
Kifc3

kinesin family member C3

chr9_-_121839460 4.855 ENSMUST00000135986.2
Ccdc13
coiled-coil domain containing 13
chr8_+_94772009 4.781 ENSMUST00000034230.5
Cx3cl1
chemokine (C-X3-C motif) ligand 1
chr7_+_139894696 4.769 ENSMUST00000151421.1
ENSMUST00000053445.9
ENSMUST00000121839.1
Kndc1


kinase non-catalytic C-lobe domain (KIND) containing 1


chr3_+_67374091 4.632 ENSMUST00000077916.5
Mlf1
myeloid leukemia factor 1
chr1_+_161142706 4.603 ENSMUST00000111608.1
ENSMUST00000052245.8
Ankrd45

ankyrin repeat domain 45

chr9_-_60688118 4.570 ENSMUST00000114034.2
ENSMUST00000065603.5
Lrrc49

leucine rich repeat containing 49

chr3_+_67374116 4.505 ENSMUST00000061322.8
Mlf1
myeloid leukemia factor 1
chr1_-_172329261 4.242 ENSMUST00000062387.2
Kcnj9
potassium inwardly-rectifying channel, subfamily J, member 9
chr11_-_67965631 4.241 ENSMUST00000021287.5
ENSMUST00000126766.1
Wdr16

WD repeat domain 16

chr11_+_70029742 4.227 ENSMUST00000132597.2
Dlg4
discs, large homolog 4 (Drosophila)
chr15_+_54745702 4.186 ENSMUST00000050027.8
Nov
nephroblastoma overexpressed gene
chr7_+_133776857 4.180 ENSMUST00000065359.5
ENSMUST00000151031.1
ENSMUST00000121560.1
Fank1


fibronectin type 3 and ankyrin repeat domains 1


chr1_+_161142661 4.123 ENSMUST00000125018.1
Ankrd45
ankyrin repeat domain 45
chr7_+_3390629 3.929 ENSMUST00000182222.1
Cacng8
calcium channel, voltage-dependent, gamma subunit 8
chr3_-_89245159 3.844 ENSMUST00000090924.6
Trim46
tripartite motif-containing 46
chr19_-_46327121 3.828 ENSMUST00000041391.4
ENSMUST00000096029.5
Psd

pleckstrin and Sec7 domain containing

chrX_+_36195938 3.805 ENSMUST00000048067.3
Zcchc12
zinc finger, CCHC domain containing 12
chr5_-_103211251 3.789 ENSMUST00000060871.5
ENSMUST00000112846.1
ENSMUST00000170792.1
ENSMUST00000112847.2
Mapk10



mitogen-activated protein kinase 10



chr7_+_45785331 3.752 ENSMUST00000120005.1
ENSMUST00000123585.1
Lmtk3

lemur tyrosine kinase 3

chrX_+_36195950 3.747 ENSMUST00000115257.1
Zcchc12
zinc finger, CCHC domain containing 12
chrX_+_36195904 3.717 ENSMUST00000115258.2
Zcchc12
zinc finger, CCHC domain containing 12
chr5_-_142550965 3.651 ENSMUST00000129212.1
ENSMUST00000110785.1
ENSMUST00000063635.8
Radil


Ras association and DIL domains


chr9_-_60687459 3.568 ENSMUST00000114032.1
ENSMUST00000166168.1
ENSMUST00000132366.1
Lrrc49


leucine rich repeat containing 49


chrX_+_36195968 3.530 ENSMUST00000115256.1
Zcchc12
zinc finger, CCHC domain containing 12
chr11_+_87760533 3.525 ENSMUST00000039627.5
ENSMUST00000100644.3
Bzrap1

benzodiazepine receptor associated protein 1

chr13_+_112987802 3.524 ENSMUST00000038404.4
Ccno
cyclin O
chr8_-_40308331 3.517 ENSMUST00000118639.1
Fgf20
fibroblast growth factor 20
chr6_-_115838412 3.468 ENSMUST00000032468.5
ENSMUST00000184428.1
Efcab12

EF-hand calcium binding domain 12

chr9_-_15627897 3.467 ENSMUST00000045513.6
Ccdc67
coiled-coil domain containing 67
chr17_+_28142267 3.462 ENSMUST00000043503.3
Scube3
signal peptide, CUB domain, EGF-like 3
chr4_+_152338887 3.426 ENSMUST00000005175.4
Chd5
chromodomain helicase DNA binding protein 5
chr10_-_13868932 3.423 ENSMUST00000019942.5
ENSMUST00000162610.1
Aig1

androgen-induced 1

chr12_+_52699297 3.396 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chr2_-_21205342 3.393 ENSMUST00000027992.2
Enkur
enkurin, TRPC channel interacting protein
chr5_-_115652974 3.372 ENSMUST00000121746.1
ENSMUST00000118576.1
Ccdc64

coiled-coil domain containing 64

chr4_+_152338619 3.348 ENSMUST00000030775.5
ENSMUST00000164662.1
Chd5

chromodomain helicase DNA binding protein 5

chr3_-_89245005 3.296 ENSMUST00000107464.1
Trim46
tripartite motif-containing 46
chr10_-_13868779 3.269 ENSMUST00000105534.3
Aig1
androgen-induced 1
chr14_-_8666236 3.268 ENSMUST00000102996.3
4930452B06Rik
RIKEN cDNA 4930452B06 gene
chr10_+_75037066 3.248 ENSMUST00000147802.1
ENSMUST00000020391.5
Rab36

RAB36, member RAS oncogene family

chr9_+_110476985 3.233 ENSMUST00000084948.4
ENSMUST00000061155.6
ENSMUST00000140686.1
ENSMUST00000084952.5
Kif9



kinesin family member 9



chr13_+_55464237 3.199 ENSMUST00000046533.7
Prr7
proline rich 7 (synaptic)
chr18_+_23803962 3.197 ENSMUST00000025127.3
Mapre2
microtubule-associated protein, RP/EB family, member 2
chr11_-_61453992 3.126 ENSMUST00000060255.7
ENSMUST00000054927.7
ENSMUST00000102661.3
Rnf112


ring finger protein 112


chr17_+_46254017 3.086 ENSMUST00000095262.4
Lrrc73
leucine rich repeat containing 73
chr1_-_87510306 3.085 ENSMUST00000027477.8
Ngef
neuronal guanine nucleotide exchange factor
chr10_+_34297421 2.993 ENSMUST00000047935.6
Tspyl4
TSPY-like 4
chr9_-_98563580 2.962 ENSMUST00000058992.2
4930579K19Rik
RIKEN cDNA 4930579K19 gene
chr12_+_72441852 2.923 ENSMUST00000162159.1
Lrrc9
leucine rich repeat containing 9
chr16_+_44394771 2.923 ENSMUST00000099742.2
Wdr52
WD repeat domain 52
chr6_-_77979652 2.875 ENSMUST00000161846.1
ENSMUST00000160894.1
Ctnna2

catenin (cadherin associated protein), alpha 2

chr18_-_46198810 2.831 ENSMUST00000167364.1
Trim36
tripartite motif-containing 36
chr10_+_80295930 2.824 ENSMUST00000105359.1
Apc2
adenomatosis polyposis coli 2
chr3_+_124321031 2.811 ENSMUST00000058994.4
Tram1l1
translocation associated membrane protein 1-like 1
chr7_-_118855602 2.792 ENSMUST00000106549.1
ENSMUST00000126792.1
Knop1

lysine rich nucleolar protein 1

chr4_+_111719975 2.766 ENSMUST00000038868.7
ENSMUST00000070513.6
ENSMUST00000153746.1
Spata6


spermatogenesis associated 6


chr11_-_72361837 2.713 ENSMUST00000108503.2
Tekt1
tektin 1
chr5_-_115300912 2.695 ENSMUST00000112090.1
Dynll1
dynein light chain LC8-type 1
chr7_-_118855984 2.649 ENSMUST00000116280.2
ENSMUST00000106550.3
ENSMUST00000063607.5
Knop1


lysine rich nucleolar protein 1


chr5_-_115300957 2.636 ENSMUST00000009157.3
Dynll1
dynein light chain LC8-type 1
chr11_+_75999912 2.619 ENSMUST00000066408.5
1700016K19Rik
RIKEN cDNA 1700016K19 gene
chr5_-_45856496 2.602 ENSMUST00000087164.3
ENSMUST00000121573.1
Lcorl

ligand dependent nuclear receptor corepressor-like

chr12_+_72441933 2.599 ENSMUST00000161284.1
Lrrc9
leucine rich repeat containing 9
chr5_-_114813943 2.551 ENSMUST00000061251.5
ENSMUST00000112160.3
1500011B03Rik

RIKEN cDNA 1500011B03 gene

chr17_-_87446854 2.530 ENSMUST00000040440.6
Calm2
calmodulin 2
chr19_+_45560569 2.528 ENSMUST00000047057.7
Dpcd
deleted in primary ciliary dyskinesia
chr18_-_43687695 2.518 ENSMUST00000082254.6
Jakmip2
janus kinase and microtubule interacting protein 2
chr7_-_118705708 2.465 ENSMUST00000038791.8
Gde1
glycerophosphodiester phosphodiesterase 1
chr15_+_100761741 2.454 ENSMUST00000023776.6
Slc4a8
solute carrier family 4 (anion exchanger), member 8
chr8_+_123212857 2.445 ENSMUST00000060133.6
Spata33
spermatogenesis associated 33
chr8_+_45627709 2.431 ENSMUST00000134321.1
ENSMUST00000135336.1
Sorbs2

sorbin and SH3 domain containing 2

chr3_+_82358056 2.430 ENSMUST00000091014.4
Map9
microtubule-associated protein 9
chr7_+_116504363 2.425 ENSMUST00000032895.8
Nucb2
nucleobindin 2
chr17_-_34603675 2.416 ENSMUST00000015622.7
Rnf5
ring finger protein 5
chr2_+_118663235 2.390 ENSMUST00000099557.3
Pak6
p21 protein (Cdc42/Rac)-activated kinase 6
chr5_+_30814571 2.378 ENSMUST00000031058.8
Mapre3
microtubule-associated protein, RP/EB family, member 3
chr15_-_98953541 2.354 ENSMUST00000097014.5
Tuba1a
tubulin, alpha 1A
chr8_-_27202542 2.339 ENSMUST00000038174.6
Got1l1
glutamic-oxaloacetic transaminase 1-like 1
chr7_+_116504409 2.332 ENSMUST00000183175.1
Nucb2
nucleobindin 2
chr9_+_59578192 2.332 ENSMUST00000118549.1
ENSMUST00000034840.3
Celf6

CUGBP, Elav-like family member 6

chr5_-_136170634 2.327 ENSMUST00000041048.1
Orai2
ORAI calcium release-activated calcium modulator 2
chr5_+_30814722 2.316 ENSMUST00000114724.1
Mapre3
microtubule-associated protein, RP/EB family, member 3
chr2_-_164857542 2.302 ENSMUST00000109316.1
ENSMUST00000156255.1
ENSMUST00000128110.1
ENSMUST00000109317.3
Pltp



phospholipid transfer protein



chr7_-_141214080 2.280 ENSMUST00000026573.5
ENSMUST00000170841.1
1600016N20Rik

RIKEN cDNA 1600016N20 gene

chr8_+_123235086 2.274 ENSMUST00000181432.1
4933417D19Rik
RIKEN cDNA 4933417D19 gene
chr4_-_43653542 2.270 ENSMUST00000084646.4
Spag8
sperm associated antigen 8
chr8_-_22805596 2.244 ENSMUST00000163739.1
Ap3m2
adaptor-related protein complex 3, mu 2 subunit
chr4_+_86930691 2.243 ENSMUST00000164590.1
Acer2
alkaline ceramidase 2
chr8_-_119575143 2.227 ENSMUST00000036049.4
Hsdl1
hydroxysteroid dehydrogenase like 1
chr11_-_76468396 2.214 ENSMUST00000065028.7
Abr
active BCR-related gene
chr5_-_137046026 2.198 ENSMUST00000144303.1
ENSMUST00000111080.1
Ap1s1

adaptor protein complex AP-1, sigma 1

chr8_-_106337987 2.180 ENSMUST00000067512.7
Smpd3
sphingomyelin phosphodiesterase 3, neutral
chr7_+_126950518 2.158 ENSMUST00000106335.1
ENSMUST00000146017.1
Sez6l2

seizure related 6 homolog like 2

chr3_-_89214378 2.124 ENSMUST00000073572.4
Mtx1
metaxin 1
chr7_+_126950837 2.090 ENSMUST00000106332.1
Sez6l2
seizure related 6 homolog like 2
chr8_+_95055094 2.081 ENSMUST00000058479.6
Ccdc135
coiled-coil domain containing 135
chr2_-_121271341 2.080 ENSMUST00000110647.1
Trp53bp1
transformation related protein 53 binding protein 1
chr7_+_126950687 2.046 ENSMUST00000106333.1
Sez6l2
seizure related 6 homolog like 2
chr15_-_79062866 2.039 ENSMUST00000151889.1
ENSMUST00000040676.4
Ankrd54

ankyrin repeat domain 54

chr4_-_43653560 2.021 ENSMUST00000107870.2
Spag8
sperm associated antigen 8
chr2_-_121271315 2.017 ENSMUST00000131245.1
Trp53bp1
transformation related protein 53 binding protein 1
chr17_+_34604262 2.009 ENSMUST00000174041.1
Agpat1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr11_+_53567361 2.007 ENSMUST00000057330.8
ENSMUST00000120613.2
ENSMUST00000173744.1
ENSMUST00000118353.2
Kif3a



kinesin family member 3A



chr7_+_139212974 1.993 ENSMUST00000016124.8
Lrrc27
leucine rich repeat containing 27
chr5_-_92042630 1.993 ENSMUST00000113140.1
ENSMUST00000113143.1
Cdkl2

cyclin-dependent kinase-like 2 (CDC2-related kinase)

chr17_+_12119274 1.989 ENSMUST00000024594.2
Agpat4
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr2_-_121271403 1.965 ENSMUST00000110648.1
Trp53bp1
transformation related protein 53 binding protein 1
chr1_+_6730051 1.962 ENSMUST00000043578.6
ENSMUST00000131467.1
ENSMUST00000150761.1
ENSMUST00000151281.1
St18



suppression of tumorigenicity 18



chr10_+_80299084 1.954 ENSMUST00000154212.1
Apc2
adenomatosis polyposis coli 2
chr4_+_111720187 1.953 ENSMUST00000084354.3
Spata6
spermatogenesis associated 6
chr2_-_134644019 1.917 ENSMUST00000110120.1
Tmx4
thioredoxin-related transmembrane protein 4
chr8_+_69832633 1.913 ENSMUST00000131637.2
ENSMUST00000081503.6
Pbx4

pre B cell leukemia homeobox 4

chr12_+_5411641 1.910 ENSMUST00000163627.1
2810032G03Rik
RIKEN cDNA 2810032G03 gene
chr2_-_118703963 1.908 ENSMUST00000104937.1
Ankrd63
ankyrin repeat domain 63
chr4_+_123183456 1.896 ENSMUST00000126995.1
Hpcal4
hippocalcin-like 4
chr7_+_16738410 1.889 ENSMUST00000086112.6
Ap2s1
adaptor-related protein complex 2, sigma 1 subunit
chr11_+_21091291 1.883 ENSMUST00000093290.5
Peli1
pellino 1
chr9_-_70141484 1.880 ENSMUST00000034749.8
Fam81a
family with sequence similarity 81, member A
chrX_-_136993027 1.878 ENSMUST00000171738.1
ENSMUST00000056674.5
ENSMUST00000129807.1
Slc25a53


solute carrier family 25, member 53


chr5_+_33983534 1.868 ENSMUST00000114382.1
Gm1673
predicted gene 1673
chr15_-_33687840 1.844 ENSMUST00000042021.3
Tspyl5
testis-specific protein, Y-encoded-like 5
chr11_-_59839828 1.840 ENSMUST00000019517.3
Cops3
COP9 (constitutive photomorphogenic) homolog, subunit 3 (Arabidopsis thaliana)
chr4_+_128654686 1.834 ENSMUST00000030588.6
ENSMUST00000136377.1
Phc2

polyhomeotic-like 2 (Drosophila)

chr6_-_77979515 1.824 ENSMUST00000159626.1
ENSMUST00000075340.5
ENSMUST00000162273.1
Ctnna2


catenin (cadherin associated protein), alpha 2


chr4_-_117125618 1.821 ENSMUST00000183310.1
Btbd19
BTB (POZ) domain containing 19
chr1_+_6730135 1.816 ENSMUST00000155921.1
St18
suppression of tumorigenicity 18
chr9_-_29412204 1.809 ENSMUST00000115237.1
Ntm
neurotrimin
chr7_+_4740111 1.794 ENSMUST00000098853.2
Suv420h2
suppressor of variegation 4-20 homolog 2 (Drosophila)
chr18_-_12305638 1.784 ENSMUST00000122408.1
ENSMUST00000118525.1
ENSMUST00000142066.1
Ankrd29


ankyrin repeat domain 29


chr2_+_71981184 1.773 ENSMUST00000090826.5
ENSMUST00000102698.3
Rapgef4

Rap guanine nucleotide exchange factor (GEF) 4

chr16_+_32099904 1.772 ENSMUST00000042869.6
Cep19
centrosomal protein 19
chr10_+_75037291 1.762 ENSMUST00000139384.1
Rab36
RAB36, member RAS oncogene family
chr9_+_107547288 1.758 ENSMUST00000010188.7
Zmynd10
zinc finger, MYND domain containing 10
chr11_+_119229092 1.756 ENSMUST00000053440.7
Ccdc40
coiled-coil domain containing 40
chr10_+_41490436 1.729 ENSMUST00000105507.3
Ppil6
peptidylprolyl isomerase (cyclophilin)-like 6
chr9_+_47530173 1.724 ENSMUST00000114548.1
ENSMUST00000152459.1
ENSMUST00000143026.1
ENSMUST00000085909.2
ENSMUST00000114547.1
ENSMUST00000034581.3
Cadm1





cell adhesion molecule 1





chr19_+_6276725 1.708 ENSMUST00000025684.3
Ehd1
EH-domain containing 1
chr6_-_90810118 1.701 ENSMUST00000101151.3
Iqsec1
IQ motif and Sec7 domain 1
chr16_+_32099781 1.699 ENSMUST00000115168.2
Cep19
centrosomal protein 19
chr10_-_39133848 1.687 ENSMUST00000134279.1
ENSMUST00000139743.1
ENSMUST00000149949.1
ENSMUST00000124941.1
ENSMUST00000125042.1
ENSMUST00000063204.2
Fam229b





family with sequence similarity 229, member B





chr7_+_4740137 1.657 ENSMUST00000130215.1
ENSMUST00000108582.3
Suv420h2

suppressor of variegation 4-20 homolog 2 (Drosophila)

chr11_-_77725281 1.646 ENSMUST00000078623.4
Cryba1
crystallin, beta A1
chr11_+_101468164 1.641 ENSMUST00000001347.6
Rnd2
Rho family GTPase 2
chr5_-_136986829 1.640 ENSMUST00000034953.7
ENSMUST00000085941.5
Znhit1

zinc finger, HIT domain containing 1

chr5_+_33983437 1.636 ENSMUST00000114384.1
ENSMUST00000094869.5
ENSMUST00000114383.1
Gm1673


predicted gene 1673


chr9_-_14771004 1.634 ENSMUST00000060330.3
1700012B09Rik
RIKEN cDNA 1700012B09 gene
chr9_+_65460926 1.633 ENSMUST00000034955.6
Spg21
spastic paraplegia 21 homolog (human)
chr10_+_86705811 1.608 ENSMUST00000061458.7
ENSMUST00000075632.6
BC030307

cDNA sequence BC030307

chr14_-_78536762 1.603 ENSMUST00000123853.1
Akap11
A kinase (PRKA) anchor protein 11
chr7_+_4740178 1.586 ENSMUST00000108583.2
Suv420h2
suppressor of variegation 4-20 homolog 2 (Drosophila)
chr8_+_13705884 1.562 ENSMUST00000166277.1
4932443I19Rik
RIKEN cDNA 4932443I19 gene
chr8_-_4259257 1.542 ENSMUST00000053252.7
Ctxn1
cortexin 1
chr11_-_74897052 1.540 ENSMUST00000057631.5
ENSMUST00000081799.5
Sgsm2

small G protein signaling modulator 2

chr16_-_33056174 1.535 ENSMUST00000115100.1
ENSMUST00000040309.8
Iqcg

IQ motif containing G

chr19_-_10457447 1.529 ENSMUST00000171400.2
Lrrc10b
leucine rich repeat containing 10B
chr4_+_109343029 1.525 ENSMUST00000030281.5
Eps15
epidermal growth factor receptor pathway substrate 15
chr10_-_39133914 1.519 ENSMUST00000135785.1
Fam229b
family with sequence similarity 229, member B
chr4_-_125065603 1.517 ENSMUST00000036383.3
Dnali1
dynein, axonemal, light intermediate polypeptide 1

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 52.7 GO:0099628 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
3.0 14.8 GO:2000325 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
1.7 7.0 GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924) negative regulation of interleukin-6 biosynthetic process(GO:0045409)
1.6 12.9 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
1.6 4.8 GO:2000836 negative regulation of glucagon secretion(GO:0070093) positive regulation of androgen secretion(GO:2000836) positive regulation of testosterone secretion(GO:2000845)
1.5 6.1 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
1.4 4.2 GO:1990523 negative regulation of SMAD protein import into nucleus(GO:0060392) endothelial cell-cell adhesion(GO:0071603) bone regeneration(GO:1990523)
1.4 12.5 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
1.2 4.8 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
1.2 4.7 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
1.0 6.8 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.9 3.7 GO:0042360 vitamin E metabolic process(GO:0042360)
0.9 2.6 GO:0016598 protein arginylation(GO:0016598)
0.9 1.7 GO:0009826 unidimensional cell growth(GO:0009826)
0.8 3.4 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.8 4.9 GO:0045218 zonula adherens maintenance(GO:0045218)
0.8 2.3 GO:0006532 aspartate biosynthetic process(GO:0006532)
0.8 21.8 GO:0048268 clathrin coat assembly(GO:0048268)
0.7 2.2 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.7 12.8 GO:0016486 peptide hormone processing(GO:0016486)
0.7 2.0 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.6 3.8 GO:0007258 JUN phosphorylation(GO:0007258)
0.6 13.0 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.5 2.4 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.5 5.3 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.5 2.9 GO:2000210 positive regulation of anoikis(GO:2000210)
0.4 1.8 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.4 2.2 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.4 3.1 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.4 9.2 GO:0071625 vocalization behavior(GO:0071625)
0.4 1.7 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.4 9.7 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.4 1.6 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.4 6.1 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.4 4.7 GO:0051823 radial glia guided migration of Purkinje cell(GO:0021942) regulation of synapse structural plasticity(GO:0051823)
0.4 3.0 GO:0003356 regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356)
0.4 0.7 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.4 2.2 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.3 15.4 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.3 4.8 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.3 5.1 GO:0007220 Notch receptor processing(GO:0007220)
0.3 3.8 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.3 1.3 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202) negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.3 1.5 GO:0032423 regulation of mismatch repair(GO:0032423)
0.3 4.8 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.3 0.9 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.3 2.7 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.3 1.7 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.3 0.6 GO:1903527 regulation of membrane tubulation(GO:1903525) positive regulation of membrane tubulation(GO:1903527)
0.3 1.4 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.3 0.8 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984) negative regulation of metalloendopeptidase activity(GO:1904684)
0.3 1.9 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.3 6.9 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.3 1.0 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.3 0.8 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.3 2.5 GO:0021678 third ventricle development(GO:0021678)
0.3 6.3 GO:0060074 synapse maturation(GO:0060074)
0.3 14.5 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.2 1.7 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.2 2.8 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.2 1.1 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.2 0.9 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.2 0.2 GO:2000331 regulation of terminal button organization(GO:2000331)
0.2 18.7 GO:0022900 electron transport chain(GO:0022900)
0.2 0.7 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.2 3.7 GO:0000338 protein deneddylation(GO:0000338)
0.2 6.3 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.2 3.2 GO:0071801 regulation of podosome assembly(GO:0071801)
0.2 1.7 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.2 1.7 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.2 1.0 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.2 0.6 GO:0018094 protein polyglycylation(GO:0018094)
0.2 2.8 GO:0007340 acrosome reaction(GO:0007340)
0.2 6.8 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.2 1.1 GO:0006172 ADP biosynthetic process(GO:0006172)
0.2 0.7 GO:0010288 response to lead ion(GO:0010288)
0.2 4.2 GO:0097320 membrane tubulation(GO:0097320)
0.2 10.2 GO:0032418 lysosome localization(GO:0032418)
0.2 0.5 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
0.2 2.0 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.2 1.4 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.2 1.2 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.2 2.4 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.2 0.6 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.2 4.2 GO:0010107 potassium ion import(GO:0010107)
0.2 2.0 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.2 0.3 GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.2 1.5 GO:0007288 sperm axoneme assembly(GO:0007288)
0.2 1.8 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.2 0.9 GO:0048102 autophagic cell death(GO:0048102)
0.2 2.0 GO:0035881 amacrine cell differentiation(GO:0035881) retinal rod cell development(GO:0046548)
0.2 0.8 GO:0051684 maintenance of Golgi location(GO:0051684)
0.2 0.3 GO:0075136 response to defenses of other organism involved in symbiotic interaction(GO:0052173) response to host defenses(GO:0052200) response to host(GO:0075136)
0.2 0.5 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.1 1.6 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 1.7 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1 5.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 2.5 GO:0002115 store-operated calcium entry(GO:0002115)
0.1 1.3 GO:0000042 protein targeting to Golgi(GO:0000042)
0.1 3.8 GO:0002437 inflammatory response to antigenic stimulus(GO:0002437)
0.1 0.6 GO:1904425 regulation of microvillus assembly(GO:0032534) negative regulation of GTP binding(GO:1904425)
0.1 0.8 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 1.3 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.1 2.5 GO:0034308 primary alcohol metabolic process(GO:0034308)
0.1 0.8 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.1 0.9 GO:0032790 ribosome disassembly(GO:0032790)
0.1 6.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 0.9 GO:1990845 adaptive thermogenesis(GO:1990845)
0.1 0.7 GO:0032782 bile acid secretion(GO:0032782)
0.1 4.4 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.7 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.1 0.2 GO:0072553 terminal button organization(GO:0072553)
0.1 0.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.5 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.1 9.5 GO:0007286 spermatid development(GO:0007286)
0.1 1.3 GO:0051639 actin filament network formation(GO:0051639)
0.1 1.3 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.1 0.8 GO:0090148 membrane fission(GO:0090148)
0.1 0.6 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 1.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 0.3 GO:0052490 suppression by virus of host apoptotic process(GO:0019050) negative regulation by symbiont of host apoptotic process(GO:0033668) modulation by virus of host apoptotic process(GO:0039526) negative regulation by symbiont of host programmed cell death(GO:0052041) negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052490) positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902220)
0.1 1.2 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 2.7 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 0.4 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.5 GO:0030913 paranodal junction assembly(GO:0030913)
0.1 2.4 GO:0071158 positive regulation of cell cycle arrest(GO:0071158)
0.1 3.3 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.1 0.6 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.1 0.6 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 1.8 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.1 5.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 2.0 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.1 3.9 GO:0019226 transmission of nerve impulse(GO:0019226)
0.1 0.5 GO:0070933 histone H4 deacetylation(GO:0070933)
0.1 1.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.3 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 2.3 GO:1903078 positive regulation of protein localization to plasma membrane(GO:1903078)
0.1 0.4 GO:1903441 protein localization to ciliary membrane(GO:1903441)
0.1 2.6 GO:0007338 single fertilization(GO:0007338)
0.1 0.2 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.1 0.3 GO:0061092 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962) regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.1 1.2 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.1 0.3 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.1 0.2 GO:0006788 heme oxidation(GO:0006788)
0.1 1.2 GO:0097120 receptor localization to synapse(GO:0097120)
0.1 7.0 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.0 2.7 GO:0060113 inner ear receptor cell differentiation(GO:0060113)
0.0 0.6 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.0 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0043312 neutrophil degranulation(GO:0043312)
0.0 2.0 GO:0034766 negative regulation of ion transmembrane transport(GO:0034766)
0.0 0.6 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143) ribonucleoside diphosphate catabolic process(GO:0009191)
0.0 0.4 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.2 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.4 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 1.4 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.7 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.0 0.4 GO:0006465 signal peptide processing(GO:0006465)
0.0 1.4 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.7 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.8 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 1.3 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.5 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.5 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.2 GO:0048793 pronephros development(GO:0048793)
0.0 0.6 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.4 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:0001193 maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193)
0.0 0.1 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 1.5 GO:0006284 base-excision repair(GO:0006284)
0.0 0.8 GO:0035067 negative regulation of histone acetylation(GO:0035067)
0.0 0.1 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.3 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.3 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.1 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.7 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.8 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.0 0.5 GO:0009566 fertilization(GO:0009566)
0.0 0.4 GO:0043248 proteasome assembly(GO:0043248)
0.0 1.6 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.2 GO:0071494 cellular response to UV-C(GO:0071494)
0.0 0.2 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.4 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 1.1 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 1.0 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 1.8 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.2 GO:0039532 negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532)
0.0 0.2 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.2 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 1.3 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.5 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0 0.1 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.0 GO:0060018 astrocyte fate commitment(GO:0060018)
0.0 0.4 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.2 GO:0090178 establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.0 GO:0009814 defense response, incompatible interaction(GO:0009814)
0.0 0.1 GO:0046321 positive regulation of fatty acid oxidation(GO:0046321)
0.0 0.9 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.3 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.5 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.3 GO:0051447 negative regulation of meiotic cell cycle(GO:0051447)
0.0 0.1 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 1.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.2 GO:1903541 regulation of exosomal secretion(GO:1903541) positive regulation of exosomal secretion(GO:1903543)
0.0 1.1 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.5 GO:0006906 vesicle fusion(GO:0006906)
0.0 1.2 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.0 0.4 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.0 0.1 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.5 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.7 GO:0051453 regulation of intracellular pH(GO:0051453)
0.0 1.6 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 0.1 GO:0006020 inositol metabolic process(GO:0006020)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
15.9 47.8 GO:0099573 glutamatergic postsynaptic density(GO:0099573)
3.1 12.2 GO:1990769 proximal neuron projection(GO:1990769)
1.6 6.2 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
1.2 9.3 GO:0001520 outer dense fiber(GO:0001520)
0.8 7.0 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.7 2.0 GO:0016939 kinesin II complex(GO:0016939)
0.6 1.7 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.5 2.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.5 7.6 GO:1904115 axon cytoplasm(GO:1904115)
0.5 8.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.4 4.9 GO:0005915 zonula adherens(GO:0005915)
0.4 4.8 GO:0031258 lamellipodium membrane(GO:0031258)
0.4 2.4 GO:0000235 astral microtubule(GO:0000235)
0.4 1.8 GO:0044316 cone cell pedicle(GO:0044316)
0.3 4.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.3 0.3 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.3 5.9 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.3 9.0 GO:0035371 microtubule plus-end(GO:0035371)
0.3 0.3 GO:0098830 presynaptic endosome(GO:0098830)
0.2 3.4 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.2 6.6 GO:0034451 centriolar satellite(GO:0034451)
0.2 5.2 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2 1.3 GO:0097443 sorting endosome(GO:0097443)
0.2 8.4 GO:0097546 ciliary base(GO:0097546)
0.2 2.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.2 0.7 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.2 6.5 GO:0035861 site of double-strand break(GO:0035861)
0.2 6.8 GO:0097440 apical dendrite(GO:0097440)
0.2 1.7 GO:0070852 cell body fiber(GO:0070852)
0.2 4.4 GO:0030137 COPI-coated vesicle(GO:0030137)
0.2 2.3 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.2 4.2 GO:0005921 gap junction(GO:0005921)
0.2 3.1 GO:0060170 ciliary membrane(GO:0060170)
0.2 1.1 GO:0002177 manchette(GO:0002177)
0.2 2.0 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 1.6 GO:0000812 Swr1 complex(GO:0000812)
0.1 11.7 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 7.0 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 0.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.7 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 1.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 3.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 6.1 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 23.8 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 0.5 GO:0005683 U7 snRNP(GO:0005683)
0.1 1.5 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 4.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.6 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 2.7 GO:0031430 M band(GO:0031430)
0.1 0.7 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 1.6 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 13.7 GO:0030141 secretory granule(GO:0030141)
0.1 2.8 GO:0016235 aggresome(GO:0016235)
0.1 2.3 GO:0030286 dynein complex(GO:0030286)
0.1 1.9 GO:0001741 XY body(GO:0001741)
0.1 3.2 GO:0002102 podosome(GO:0002102)
0.1 0.2 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 1.1 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 0.9 GO:0005688 U6 snRNP(GO:0005688)
0.1 0.5 GO:0005638 lamin filament(GO:0005638)
0.1 0.2 GO:0071001 U4/U6 snRNP(GO:0071001)
0.1 2.4 GO:0060077 inhibitory synapse(GO:0060077)
0.1 3.1 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 1.3 GO:0070822 Sin3-type complex(GO:0070822)
0.1 0.7 GO:0005869 dynactin complex(GO:0005869)
0.1 0.9 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.3 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 0.5 GO:0042382 paraspeckles(GO:0042382)
0.1 2.5 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 0.3 GO:0032426 stereocilium tip(GO:0032426)
0.1 1.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.2 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.1 3.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 2.0 GO:0031201 SNARE complex(GO:0031201)
0.1 0.4 GO:0097413 Lewy body(GO:0097413)
0.1 2.2 GO:0005801 cis-Golgi network(GO:0005801)
0.1 19.1 GO:0016607 nuclear speck(GO:0016607)
0.1 17.5 GO:0005874 microtubule(GO:0005874)
0.1 5.9 GO:0031514 motile cilium(GO:0031514)
0.1 1.3 GO:0005930 axoneme(GO:0005930)
0.0 0.6 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.5 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.4 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.7 GO:0030008 TRAPP complex(GO:0030008)
0.0 1.4 GO:0031226 intrinsic component of plasma membrane(GO:0031226)
0.0 6.7 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 1.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 30.6 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 2.1 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 2.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.7 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.3 GO:0032797 SMN complex(GO:0032797)
0.0 0.4 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 2.2 GO:0000922 spindle pole(GO:0000922)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 2.5 GO:0043679 axon terminus(GO:0043679)
0.0 0.8 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.5 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 1.3 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 2.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.5 GO:0035102 PRC1 complex(GO:0035102)
0.0 1.8 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.1 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 3.4 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.7 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304)
0.0 6.5 GO:0009986 cell surface(GO:0009986)
0.0 0.1 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.1 GO:0061700 Seh1-associated complex(GO:0035859) GATOR2 complex(GO:0061700)
0.0 0.2 GO:0010369 chromocenter(GO:0010369)
0.0 0.6 GO:0005776 autophagosome(GO:0005776)
0.0 0.7 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.1 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.1 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 1.0 GO:0042641 actomyosin(GO:0042641)
0.0 1.6 GO:0005769 early endosome(GO:0005769)
0.0 0.4 GO:0015030 Cajal body(GO:0015030)
0.0 0.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
6.1 18.3 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
4.1 49.5 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
2.5 20.3 GO:0032051 clathrin light chain binding(GO:0032051)
1.7 6.8 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
1.3 5.4 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
1.1 2.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
1.0 6.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.9 3.8 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.9 7.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.9 3.5 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.9 7.0 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.9 4.3 GO:0032027 myosin light chain binding(GO:0032027)
0.8 4.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.8 2.3 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.7 2.2 GO:0071633 dihydroceramidase activity(GO:0071633)
0.6 2.5 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.6 4.8 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.5 14.8 GO:0032183 SUMO binding(GO:0032183)
0.5 1.5 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.5 5.3 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.5 1.4 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.4 2.8 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.4 15.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.3 2.5 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.3 0.9 GO:0050816 phosphothreonine binding(GO:0050816)
0.3 6.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.3 12.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.3 9.3 GO:0005112 Notch binding(GO:0005112)
0.3 1.0 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.3 1.5 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.2 3.5 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.2 6.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 0.9 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.2 0.7 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.2 1.1 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.2 1.4 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.2 0.6 GO:0070736 protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736)
0.2 4.5 GO:0042171 lysophosphatidic acid acyltransferase activity(GO:0042171)
0.2 2.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.2 4.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.2 1.3 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.2 2.8 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.2 1.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 1.6 GO:0042609 CD4 receptor binding(GO:0042609)
0.2 0.9 GO:1904288 BAT3 complex binding(GO:1904288)
0.2 1.0 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2 0.5 GO:0071208 histone pre-mRNA DCP binding(GO:0071208) U7 snRNA binding(GO:0071209)
0.2 4.8 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.2 1.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.2 2.4 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 2.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 6.0 GO:0045182 translation regulator activity(GO:0045182)
0.1 2.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 37.2 GO:0008017 microtubule binding(GO:0008017)
0.1 3.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 5.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 6.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.4 GO:0005119 smoothened binding(GO:0005119)
0.1 2.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 1.3 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.1 4.4 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 3.9 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 0.7 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 1.1 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.6 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 2.1 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 0.2 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1 0.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.4 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.1 3.8 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 0.4 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 0.8 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 1.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 2.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 0.5 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 0.6 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 0.7 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 1.2 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 1.1 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.1 2.0 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 1.8 GO:0030552 cAMP binding(GO:0030552)
0.1 1.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.5 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.1 0.7 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.8 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 0.5 GO:0003777 microtubule motor activity(GO:0003777)
0.1 0.9 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 1.5 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 2.7 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.6 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.2 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.3 GO:0005047 signal recognition particle binding(GO:0005047) 7S RNA binding(GO:0008312)
0.0 0.2 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 1.3 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 1.7 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.4 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 3.9 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.6 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 3.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.8 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 2.3 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.6 GO:0031005 filamin binding(GO:0031005)
0.0 0.3 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.0 0.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.7 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 1.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.2 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.5 GO:0043274 phospholipase binding(GO:0043274)
0.0 1.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.8 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0034711 inhibin binding(GO:0034711)
0.0 0.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 1.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.5 GO:0008483 transaminase activity(GO:0008483)
0.0 0.4 GO:0070840 dynein complex binding(GO:0070840)
0.0 1.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.8 GO:0050699 WW domain binding(GO:0050699)
0.0 4.7 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 0.2 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 4.5 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.4 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.0 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.1 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 1.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.7 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.1 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 0.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.4 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 1.6 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.1 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0015266 protein channel activity(GO:0015266)
0.0 0.8 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 47.8 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.3 9.1 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.2 4.0 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 1.8 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 8.3 PID_LKB1_PATHWAY LKB1 signaling events
0.1 1.3 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.1 6.7 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.1 7.8 PID_NOTCH_PATHWAY Notch signaling pathway
0.1 4.9 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 3.9 PID_FOXO_PATHWAY FoxO family signaling
0.1 2.2 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.1 9.1 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 1.7 PID_ARF6_PATHWAY Arf6 signaling events
0.1 0.7 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.1 1.5 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.1 2.2 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.1 0.5 PID_IL5_PATHWAY IL5-mediated signaling events
0.1 10.7 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 2.5 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.0 1.5 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 3.7 PID_P73PATHWAY p73 transcription factor network
0.0 1.5 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.7 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.8 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.5 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 0.3 PID_IL3_PATHWAY IL3-mediated signaling events
0.0 0.4 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.7 PID_ARF_3PATHWAY Arf1 pathway
0.0 0.9 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.9 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 3.2 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.6 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 0.8 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 50.4 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.5 13.0 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.3 1.3 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.3 2.4 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.3 3.7 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.3 1.9 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.3 6.5 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.2 8.8 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS Genes involved in Trafficking of AMPA receptors
0.2 3.0 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.2 4.4 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 3.8 REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.2 6.7 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.2 2.2 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 4.7 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.1 1.7 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 9.5 REACTOME_REGULATION_OF_INSULIN_SECRETION Genes involved in Regulation of Insulin Secretion
0.1 5.0 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 1.3 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.1 2.6 REACTOME_KINESINS Genes involved in Kinesins
0.1 3.3 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 6.4 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.1 1.4 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 1.3 REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.1 0.8 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 0.9 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 1.1 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 2.9 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.1 1.7 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.3 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.1 0.9 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.0 0.5 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.8 REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.6 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 1.2 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.1 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.5 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 1.2 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 1.5 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.6 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.8 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 2.2 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_ Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.6 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.5 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 1.1 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 1.1 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.6 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.9 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.9 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.9 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 2.3 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.1 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.7 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 1.6 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME_FORMATION_OF_TRANSCRIPTION_COUPLED_NER_TC_NER_REPAIR_COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.4 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.5 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins