Motif ID: Spdef
Z-value: 0.472

Transcription factors associated with Spdef:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Spdef | ENSMUSG00000024215.7 | Spdef |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Spdef | mm10_v2_chr17_-_27728889_27728956 | 0.02 | 9.1e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 1.7 | GO:0072223 | metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262) |
0.4 | 1.2 | GO:0002447 | eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308) regulation of eosinophil activation(GO:1902566) |
0.3 | 0.9 | GO:0061349 | Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) hypophysis morphogenesis(GO:0048850) cervix development(GO:0060067) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) |
0.3 | 0.9 | GO:0019085 | early viral transcription(GO:0019085) |
0.2 | 0.7 | GO:0043323 | positive regulation of natural killer cell degranulation(GO:0043323) |
0.2 | 0.6 | GO:0030200 | heparan sulfate proteoglycan catabolic process(GO:0030200) |
0.2 | 0.6 | GO:0071921 | establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) |
0.2 | 1.1 | GO:0036438 | maintenance of lens transparency(GO:0036438) |
0.1 | 0.7 | GO:0044314 | protein K27-linked ubiquitination(GO:0044314) |
0.1 | 0.6 | GO:0086046 | membrane depolarization during SA node cell action potential(GO:0086046) |
0.1 | 0.4 | GO:0002946 | tRNA C5-cytosine methylation(GO:0002946) |
0.1 | 0.3 | GO:0018214 | peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214) |
0.1 | 0.7 | GO:0090070 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
0.1 | 1.5 | GO:0071257 | cellular response to electrical stimulus(GO:0071257) |
0.1 | 0.7 | GO:0060075 | regulation of resting membrane potential(GO:0060075) |
0.1 | 0.3 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
0.1 | 0.4 | GO:0021506 | anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995) |
0.1 | 0.9 | GO:2001054 | negative regulation of mesenchymal cell apoptotic process(GO:2001054) |
0.1 | 0.8 | GO:0070317 | negative regulation of smooth muscle cell differentiation(GO:0051151) negative regulation of G0 to G1 transition(GO:0070317) |
0.1 | 0.8 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
0.1 | 0.4 | GO:2000623 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
0.1 | 0.6 | GO:1901098 | positive regulation of autophagosome maturation(GO:1901098) |
0.1 | 1.3 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
0.1 | 0.9 | GO:0042473 | outer ear morphogenesis(GO:0042473) |
0.1 | 0.3 | GO:2000318 | positive regulation of T-helper 17 type immune response(GO:2000318) |
0.1 | 0.2 | GO:0044313 | protein K6-linked deubiquitination(GO:0044313) |
0.1 | 0.3 | GO:0006776 | vitamin A metabolic process(GO:0006776) |
0.1 | 0.5 | GO:2000483 | negative regulation of interleukin-8 secretion(GO:2000483) |
0.1 | 0.6 | GO:0060662 | tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662) |
0.1 | 0.2 | GO:0072720 | response to sorbitol(GO:0072708) response to dithiothreitol(GO:0072720) |
0.1 | 1.6 | GO:0034315 | regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315) |
0.1 | 0.7 | GO:0070574 | cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574) |
0.1 | 0.4 | GO:0036462 | TRAIL-activated apoptotic signaling pathway(GO:0036462) |
0.1 | 0.5 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
0.1 | 0.2 | GO:0090187 | zymogen granule exocytosis(GO:0070625) positive regulation of pancreatic juice secretion(GO:0090187) |
0.1 | 0.1 | GO:0072076 | formation of anatomical boundary(GO:0048859) nephrogenic mesenchyme development(GO:0072076) |
0.1 | 0.3 | GO:0061428 | embryonic heart tube left/right pattern formation(GO:0060971) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428) |
0.1 | 0.3 | GO:1901668 | regulation of superoxide dismutase activity(GO:1901668) |
0.1 | 0.6 | GO:0070236 | negative regulation of activation-induced cell death of T cells(GO:0070236) |
0.1 | 0.2 | GO:0035526 | retrograde transport, plasma membrane to Golgi(GO:0035526) |
0.1 | 0.4 | GO:0006172 | ADP biosynthetic process(GO:0006172) |
0.1 | 0.5 | GO:0006265 | DNA topological change(GO:0006265) |
0.1 | 0.2 | GO:0019276 | UDP-N-acetylgalactosamine metabolic process(GO:0019276) |
0.1 | 0.4 | GO:0097473 | cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473) |
0.1 | 0.2 | GO:2000256 | endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163) positive regulation of male germ cell proliferation(GO:2000256) |
0.1 | 0.2 | GO:0043988 | histone H3-S28 phosphorylation(GO:0043988) |
0.1 | 0.6 | GO:0060693 | regulation of branching involved in salivary gland morphogenesis(GO:0060693) |
0.1 | 0.4 | GO:2001185 | regulation of CD8-positive, alpha-beta T cell activation(GO:2001185) |
0.1 | 0.5 | GO:0032471 | negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471) |
0.1 | 0.1 | GO:0032817 | regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819) |
0.1 | 0.2 | GO:0036015 | response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016) |
0.0 | 0.1 | GO:1902915 | negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915) |
0.0 | 0.1 | GO:2000850 | negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850) |
0.0 | 0.3 | GO:0042985 | negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) |
0.0 | 0.4 | GO:0007016 | cytoskeletal anchoring at plasma membrane(GO:0007016) |
0.0 | 0.3 | GO:0031642 | negative regulation of myelination(GO:0031642) |
0.0 | 0.1 | GO:0000973 | posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) |
0.0 | 0.8 | GO:0016558 | protein import into peroxisome matrix(GO:0016558) |
0.0 | 0.3 | GO:0008343 | adult feeding behavior(GO:0008343) |
0.0 | 0.2 | GO:0090521 | glomerular visceral epithelial cell migration(GO:0090521) |
0.0 | 0.4 | GO:1904153 | negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153) |
0.0 | 0.1 | GO:1900060 | negative regulation of ceramide biosynthetic process(GO:1900060) |
0.0 | 0.1 | GO:0044837 | assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837) |
0.0 | 0.3 | GO:0061042 | vascular wound healing(GO:0061042) |
0.0 | 0.2 | GO:1904217 | regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222) |
0.0 | 0.2 | GO:0031022 | nuclear migration along microfilament(GO:0031022) |
0.0 | 0.6 | GO:0006044 | N-acetylglucosamine metabolic process(GO:0006044) |
0.0 | 0.3 | GO:0006691 | leukotriene metabolic process(GO:0006691) |
0.0 | 0.1 | GO:0036092 | phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092) |
0.0 | 0.1 | GO:0035752 | lysosomal lumen pH elevation(GO:0035752) |
0.0 | 0.2 | GO:0032485 | regulation of Ral protein signal transduction(GO:0032485) |
0.0 | 0.2 | GO:0035511 | oxidative DNA demethylation(GO:0035511) |
0.0 | 1.1 | GO:0001937 | negative regulation of endothelial cell proliferation(GO:0001937) |
0.0 | 0.1 | GO:0016256 | N-glycan processing to lysosome(GO:0016256) |
0.0 | 0.4 | GO:0051639 | actin filament network formation(GO:0051639) |
0.0 | 0.3 | GO:0030238 | male sex determination(GO:0030238) |
0.0 | 0.2 | GO:0097039 | protein linear polyubiquitination(GO:0097039) |
0.0 | 0.1 | GO:0032201 | telomere maintenance via semi-conservative replication(GO:0032201) |
0.0 | 1.0 | GO:2001222 | regulation of neuron migration(GO:2001222) |
0.0 | 0.1 | GO:0010756 | positive regulation of plasminogen activation(GO:0010756) |
0.0 | 0.1 | GO:0021764 | amygdala development(GO:0021764) |
0.0 | 0.2 | GO:0007220 | Notch receptor processing(GO:0007220) |
0.0 | 0.1 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
0.0 | 0.4 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
0.0 | 0.2 | GO:0097151 | positive regulation of inhibitory postsynaptic potential(GO:0097151) |
0.0 | 0.2 | GO:0000479 | endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479) |
0.0 | 0.7 | GO:0030520 | intracellular estrogen receptor signaling pathway(GO:0030520) |
0.0 | 0.2 | GO:0061470 | T follicular helper cell differentiation(GO:0061470) |
0.0 | 0.1 | GO:0031584 | activation of phospholipase D activity(GO:0031584) |
0.0 | 0.1 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
0.0 | 0.1 | GO:0018202 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) peptidyl-histidine modification(GO:0018202) |
0.0 | 0.3 | GO:0097352 | autophagosome maturation(GO:0097352) |
0.0 | 0.4 | GO:0001921 | positive regulation of receptor recycling(GO:0001921) |
0.0 | 0.3 | GO:0060749 | mammary gland alveolus development(GO:0060749) mammary gland lobule development(GO:0061377) |
0.0 | 0.1 | GO:0045903 | positive regulation of translational fidelity(GO:0045903) |
0.0 | 0.5 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
0.0 | 0.2 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663) |
0.0 | 0.1 | GO:0018342 | protein prenylation(GO:0018342) prenylation(GO:0097354) |
0.0 | 0.6 | GO:0007029 | endoplasmic reticulum organization(GO:0007029) |
0.0 | 0.0 | GO:0006105 | succinate metabolic process(GO:0006105) |
0.0 | 1.5 | GO:0008033 | tRNA processing(GO:0008033) |
0.0 | 0.2 | GO:0060218 | hematopoietic stem cell differentiation(GO:0060218) |
0.0 | 0.3 | GO:0006829 | zinc II ion transport(GO:0006829) |
0.0 | 0.5 | GO:0051496 | positive regulation of stress fiber assembly(GO:0051496) |
0.0 | 0.6 | GO:0030835 | negative regulation of actin filament depolymerization(GO:0030835) |
0.0 | 0.1 | GO:0031848 | protection from non-homologous end joining at telomere(GO:0031848) |
0.0 | 0.6 | GO:0045669 | positive regulation of osteoblast differentiation(GO:0045669) |
0.0 | 0.3 | GO:0034724 | DNA replication-independent nucleosome organization(GO:0034724) |
0.0 | 0.3 | GO:0002063 | chondrocyte development(GO:0002063) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 1.2 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
0.2 | 1.2 | GO:0000322 | storage vacuole(GO:0000322) |
0.2 | 0.7 | GO:1902937 | inward rectifier potassium channel complex(GO:1902937) |
0.1 | 0.4 | GO:0030690 | Noc1p-Noc2p complex(GO:0030690) |
0.1 | 0.5 | GO:1990415 | Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429) |
0.1 | 0.2 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
0.1 | 0.4 | GO:0045251 | mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251) |
0.1 | 0.3 | GO:0097543 | ciliary inversin compartment(GO:0097543) |
0.1 | 0.3 | GO:0008623 | CHRAC(GO:0008623) |
0.1 | 0.2 | GO:0035101 | FACT complex(GO:0035101) |
0.1 | 0.6 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
0.1 | 0.6 | GO:0033179 | proton-transporting V-type ATPase, V0 domain(GO:0033179) |
0.1 | 1.5 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
0.1 | 1.4 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
0.1 | 0.3 | GO:0005796 | Golgi lumen(GO:0005796) |
0.1 | 1.7 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
0.1 | 0.3 | GO:1990130 | Iml1 complex(GO:1990130) |
0.1 | 0.6 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
0.0 | 0.2 | GO:0071797 | LUBAC complex(GO:0071797) |
0.0 | 0.3 | GO:0005964 | phosphorylase kinase complex(GO:0005964) |
0.0 | 0.1 | GO:0032444 | activin responsive factor complex(GO:0032444) |
0.0 | 0.1 | GO:0034272 | phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272) |
0.0 | 0.3 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
0.0 | 0.2 | GO:0070765 | gamma-secretase complex(GO:0070765) |
0.0 | 0.1 | GO:0032280 | symmetric synapse(GO:0032280) |
0.0 | 0.1 | GO:0035339 | SPOTS complex(GO:0035339) |
0.0 | 0.1 | GO:0071001 | U4/U6 snRNP(GO:0071001) |
0.0 | 0.9 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
0.0 | 2.5 | GO:0000118 | histone deacetylase complex(GO:0000118) |
0.0 | 0.4 | GO:0016460 | myosin II complex(GO:0016460) |
0.0 | 0.8 | GO:0032040 | small-subunit processome(GO:0032040) |
0.0 | 0.2 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
0.0 | 0.4 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
0.0 | 0.3 | GO:0030126 | COPI vesicle coat(GO:0030126) |
0.0 | 0.1 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
0.0 | 0.4 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
0.0 | 0.2 | GO:0097427 | microtubule bundle(GO:0097427) |
0.0 | 0.1 | GO:0070847 | core mediator complex(GO:0070847) |
0.0 | 0.2 | GO:0032433 | filopodium tip(GO:0032433) |
0.0 | 0.1 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
0.0 | 0.5 | GO:0030904 | retromer complex(GO:0030904) |
0.0 | 0.2 | GO:0017119 | Golgi transport complex(GO:0017119) |
0.0 | 0.6 | GO:0031901 | early endosome membrane(GO:0031901) |
0.0 | 0.4 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
0.0 | 0.7 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
0.0 | 0.8 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
0.0 | 0.3 | GO:0046540 | U4/U6 x U5 tri-snRNP complex(GO:0046540) |
0.0 | 0.1 | GO:0097255 | R2TP complex(GO:0097255) |
0.0 | 0.1 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
0.0 | 0.2 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
0.0 | 1.3 | GO:0032432 | actin filament bundle(GO:0032432) |
0.0 | 1.1 | GO:0016605 | PML body(GO:0016605) |
0.0 | 0.0 | GO:0000801 | central element(GO:0000801) |
0.0 | 0.2 | GO:0044447 | axoneme part(GO:0044447) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 1.7 | GO:0044729 | hemi-methylated DNA-binding(GO:0044729) |
0.4 | 1.1 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
0.3 | 0.9 | GO:0005110 | frizzled-2 binding(GO:0005110) |
0.3 | 1.2 | GO:0016230 | sphingomyelin phosphodiesterase activator activity(GO:0016230) |
0.2 | 1.5 | GO:0016300 | tRNA (uracil) methyltransferase activity(GO:0016300) |
0.1 | 0.6 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
0.1 | 0.6 | GO:0008332 | low voltage-gated calcium channel activity(GO:0008332) |
0.1 | 0.4 | GO:0046899 | nucleoside triphosphate adenylate kinase activity(GO:0046899) |
0.1 | 0.4 | GO:0031752 | D5 dopamine receptor binding(GO:0031752) |
0.1 | 0.6 | GO:0004342 | glucosamine-6-phosphate deaminase activity(GO:0004342) |
0.1 | 1.8 | GO:0017166 | vinculin binding(GO:0017166) |
0.1 | 0.4 | GO:0035877 | death effector domain binding(GO:0035877) |
0.1 | 0.3 | GO:0016501 | prostacyclin receptor activity(GO:0016501) |
0.1 | 0.5 | GO:0003917 | DNA topoisomerase type I activity(GO:0003917) |
0.1 | 0.4 | GO:0097003 | adipokinetic hormone receptor activity(GO:0097003) |
0.1 | 0.4 | GO:0004174 | electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649) |
0.1 | 0.2 | GO:0001888 | glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888) |
0.1 | 0.3 | GO:0045131 | pre-mRNA branch point binding(GO:0045131) |
0.1 | 1.0 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
0.1 | 0.5 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
0.1 | 0.2 | GO:0001042 | RNA polymerase I core binding(GO:0001042) |
0.1 | 0.7 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
0.1 | 0.2 | GO:0034511 | U3 snoRNA binding(GO:0034511) |
0.1 | 0.2 | GO:0051377 | mannose-ethanolamine phosphotransferase activity(GO:0051377) |
0.1 | 0.2 | GO:1990450 | linear polyubiquitin binding(GO:1990450) |
0.1 | 0.3 | GO:0004095 | carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416) |
0.1 | 0.7 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
0.1 | 0.2 | GO:0051747 | cytosine C-5 DNA demethylase activity(GO:0051747) |
0.1 | 0.3 | GO:0052833 | inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834) |
0.0 | 0.4 | GO:0005131 | growth hormone receptor binding(GO:0005131) |
0.0 | 0.4 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
0.0 | 0.5 | GO:0004445 | inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030) |
0.0 | 1.5 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
0.0 | 0.2 | GO:0008427 | calcium-dependent protein kinase inhibitor activity(GO:0008427) |
0.0 | 0.3 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
0.0 | 0.6 | GO:0008484 | sulfuric ester hydrolase activity(GO:0008484) |
0.0 | 0.3 | GO:0004689 | phosphorylase kinase activity(GO:0004689) |
0.0 | 0.4 | GO:0016428 | tRNA (cytosine-5-)-methyltransferase activity(GO:0016428) |
0.0 | 0.1 | GO:0000033 | alpha-1,3-mannosyltransferase activity(GO:0000033) |
0.0 | 0.1 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
0.0 | 0.6 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
0.0 | 0.6 | GO:0035497 | cAMP response element binding(GO:0035497) |
0.0 | 0.3 | GO:0050308 | sugar-phosphatase activity(GO:0050308) |
0.0 | 0.1 | GO:0004045 | aminoacyl-tRNA hydrolase activity(GO:0004045) |
0.0 | 0.3 | GO:0048038 | quinone binding(GO:0048038) |
0.0 | 2.0 | GO:0005518 | collagen binding(GO:0005518) |
0.0 | 0.7 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.0 | 0.2 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
0.0 | 0.3 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
0.0 | 0.7 | GO:0030515 | snoRNA binding(GO:0030515) |
0.0 | 0.6 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
0.0 | 0.8 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
0.0 | 0.3 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
0.0 | 0.3 | GO:0031702 | type 1 angiotensin receptor binding(GO:0031702) |
0.0 | 1.0 | GO:0050681 | androgen receptor binding(GO:0050681) |
0.0 | 1.0 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
0.0 | 0.7 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
0.0 | 0.1 | GO:0030621 | U4 snRNA binding(GO:0030621) |
0.0 | 0.5 | GO:0071949 | FAD binding(GO:0071949) |
0.0 | 0.1 | GO:0003976 | UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976) |
0.0 | 0.1 | GO:0010385 | double-stranded methylated DNA binding(GO:0010385) |
0.0 | 0.1 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
0.0 | 0.1 | GO:0008318 | protein prenyltransferase activity(GO:0008318) |
0.0 | 0.4 | GO:0008143 | poly(A) binding(GO:0008143) |
0.0 | 0.3 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
0.0 | 0.2 | GO:0003688 | DNA replication origin binding(GO:0003688) |
0.0 | 0.1 | GO:0043141 | ATP-dependent 5'-3' DNA helicase activity(GO:0043141) |
0.0 | 0.2 | GO:0008409 | 5'-3' exonuclease activity(GO:0008409) |
0.0 | 0.0 | GO:0016635 | succinate dehydrogenase (ubiquinone) activity(GO:0008177) oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635) |
0.0 | 0.5 | GO:0004177 | aminopeptidase activity(GO:0004177) |
0.0 | 2.0 | GO:0051015 | actin filament binding(GO:0051015) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 0.2 | ST_IL_13_PATHWAY | Interleukin 13 (IL-13) Pathway |
0.0 | 1.5 | PID_PRL_SIGNALING_EVENTS_PATHWAY | Signaling events mediated by PRL |
0.0 | 0.4 | SA_FAS_SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
0.0 | 0.6 | PID_SYNDECAN_3_PATHWAY | Syndecan-3-mediated signaling events |
0.0 | 0.4 | PID_ECADHERIN_KERATINOCYTE_PATHWAY | E-cadherin signaling in keratinocytes |
0.0 | 0.9 | PID_WNT_CANONICAL_PATHWAY | Canonical Wnt signaling pathway |
0.0 | 0.9 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
0.0 | 1.5 | PID_ECADHERIN_STABILIZATION_PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
0.0 | 0.8 | PID_HDAC_CLASSIII_PATHWAY | Signaling events mediated by HDAC Class III |
0.0 | 0.5 | PID_ARF6_DOWNSTREAM_PATHWAY | Arf6 downstream pathway |
0.0 | 0.7 | PID_HEDGEHOG_2PATHWAY | Signaling events mediated by the Hedgehog family |
0.0 | 0.2 | PID_S1P_S1P4_PATHWAY | S1P4 pathway |
0.0 | 0.4 | PID_NECTIN_PATHWAY | Nectin adhesion pathway |
0.0 | 0.6 | PID_ATM_PATHWAY | ATM pathway |
0.0 | 0.3 | PID_ARF_3PATHWAY | Arf1 pathway |
0.0 | 0.1 | PID_ALK2_PATHWAY | ALK2 signaling events |
0.0 | 0.7 | PID_TRKR_PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
0.0 | 1.4 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.0 | 1.0 | PID_HDAC_CLASSI_PATHWAY | Signaling events mediated by HDAC Class I |
0.0 | 0.2 | PID_IL27_PATHWAY | IL27-mediated signaling events |
0.0 | 0.2 | PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY | Signaling mediated by p38-alpha and p38-beta |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 0.7 | REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS | Genes involved in Tandem pore domain potassium channels |
0.1 | 1.5 | REACTOME_GAP_JUNCTION_DEGRADATION | Genes involved in Gap junction degradation |
0.1 | 0.8 | REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
0.0 | 1.8 | REACTOME_SMOOTH_MUSCLE_CONTRACTION | Genes involved in Smooth Muscle Contraction |
0.0 | 1.8 | REACTOME_INTERFERON_ALPHA_BETA_SIGNALING | Genes involved in Interferon alpha/beta signaling |
0.0 | 0.7 | REACTOME_ZINC_TRANSPORTERS | Genes involved in Zinc transporters |
0.0 | 0.6 | REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 | Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 |
0.0 | 0.1 | REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR | Genes involved in Thromboxane signalling through TP receptor |
0.0 | 0.6 | REACTOME_HS_GAG_DEGRADATION | Genes involved in HS-GAG degradation |
0.0 | 0.4 | REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
0.0 | 0.8 | REACTOME_PIP3_ACTIVATES_AKT_SIGNALING | Genes involved in PIP3 activates AKT signaling |
0.0 | 0.3 | REACTOME_COPI_MEDIATED_TRANSPORT | Genes involved in COPI Mediated Transport |
0.0 | 0.9 | REACTOME_GLUCOSE_TRANSPORT | Genes involved in Glucose transport |
0.0 | 0.3 | REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
0.0 | 0.2 | REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS | Genes involved in Thrombin signalling through proteinase activated receptors (PARs) |
0.0 | 0.2 | REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR | Genes involved in Regulated proteolysis of p75NTR |
0.0 | 0.5 | REACTOME_SYNTHESIS_OF_PA | Genes involved in Synthesis of PA |
0.0 | 0.3 | REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
0.0 | 0.1 | REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE | Genes involved in mRNA Decay by 3' to 5' Exoribonuclease |
0.0 | 0.1 | REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES | Genes involved in Generation of second messenger molecules |
0.0 | 0.6 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
0.0 | 0.1 | REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRONLESS_TRANSCRIPT | Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript |
0.0 | 0.1 | REACTOME_G_ALPHA1213_SIGNALLING_EVENTS | Genes involved in G alpha (12/13) signalling events |
0.0 | 0.5 | REACTOME_MRNA_SPLICING_MINOR_PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |