Motif ID: Rreb1

Z-value: 0.863


Transcription factors associated with Rreb1:

Gene SymbolEntrez IDGene Name
Rreb1 ENSMUSG00000039087.10 Rreb1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rreb1mm10_v2_chr13_+_37826225_378263150.038.6e-01Click!


Activity profile for motif Rreb1.

activity profile for motif Rreb1


Sorted Z-values histogram for motif Rreb1

Sorted Z-values for motif Rreb1



Network of associatons between targets according to the STRING database.



First level regulatory network of Rreb1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_+_83791939 5.295 ENSMUST00000172115.1
ENSMUST00000172398.1
Mpped1

metallophosphoesterase domain containing 1

chr17_+_35076902 5.183 ENSMUST00000172494.1
ENSMUST00000172678.1
ENSMUST00000013910.4
Ly6g6e


lymphocyte antigen 6 complex, locus G6E


chr11_-_69369377 4.469 ENSMUST00000092971.6
ENSMUST00000108661.1
Chd3

chromodomain helicase DNA binding protein 3

chr13_+_43615710 3.670 ENSMUST00000059986.2
Rnf182
ring finger protein 182
chr8_+_57455898 3.535 ENSMUST00000034023.3
Scrg1
scrapie responsive gene 1
chr11_+_67586675 3.418 ENSMUST00000108680.1
Gas7
growth arrest specific 7
chr11_+_67586520 3.355 ENSMUST00000108682.2
Gas7
growth arrest specific 7
chr17_+_35077080 3.328 ENSMUST00000172959.1
Ly6g6e
lymphocyte antigen 6 complex, locus G6E
chr5_+_37047464 3.029 ENSMUST00000137019.1
Jakmip1
janus kinase and microtubule interacting protein 1
chr5_-_122002340 2.965 ENSMUST00000134326.1
Cux2
cut-like homeobox 2
chr13_+_109632760 2.572 ENSMUST00000135275.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr2_-_33371400 2.490 ENSMUST00000113164.1
ENSMUST00000091039.2
ENSMUST00000042615.6
Ralgps1


Ral GEF with PH domain and SH3 binding motif 1


chr12_+_81026800 2.422 ENSMUST00000110347.2
ENSMUST00000021564.4
ENSMUST00000129362.1
Smoc1


SPARC related modular calcium binding 1


chr3_-_73056943 2.310 ENSMUST00000059407.7
Slitrk3
SLIT and NTRK-like family, member 3
chr2_-_33371486 2.275 ENSMUST00000113165.1
Ralgps1
Ral GEF with PH domain and SH3 binding motif 1
chr5_-_89883321 2.241 ENSMUST00000163159.1
ENSMUST00000061427.5
Adamts3

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 3

chr16_-_67620880 2.197 ENSMUST00000114292.1
ENSMUST00000120898.1
Cadm2

cell adhesion molecule 2

chr8_-_11008458 2.196 ENSMUST00000040514.6
Irs2
insulin receptor substrate 2
chr14_-_34201604 2.158 ENSMUST00000096019.2
Gprin2
G protein regulated inducer of neurite outgrowth 2
chr12_+_12262139 2.145 ENSMUST00000069066.6
ENSMUST00000069005.8
Fam49a

family with sequence similarity 49, member A

chr18_-_31949571 2.114 ENSMUST00000064016.5
Gpr17
G protein-coupled receptor 17
chr12_+_29528382 2.100 ENSMUST00000049784.9
Myt1l
myelin transcription factor 1-like
chr12_+_81859964 2.088 ENSMUST00000021567.5
Pcnx
pecanex homolog (Drosophila)
chr16_-_67620805 2.051 ENSMUST00000120594.1
Cadm2
cell adhesion molecule 2
chr10_+_80300997 1.955 ENSMUST00000140828.1
ENSMUST00000138909.1
Apc2

adenomatosis polyposis coli 2

chr13_+_42866247 1.810 ENSMUST00000131942.1
Phactr1
phosphatase and actin regulator 1
chr13_+_43615950 1.806 ENSMUST00000161817.1
Rnf182
ring finger protein 182
chr3_-_89245159 1.708 ENSMUST00000090924.6
Trim46
tripartite motif-containing 46
chr7_+_5056856 1.708 ENSMUST00000131368.1
ENSMUST00000123956.1
Ccdc106

coiled-coil domain containing 106

chr17_+_6106464 1.703 ENSMUST00000142030.1
Tulp4
tubby like protein 4
chr11_-_70229677 1.697 ENSMUST00000153449.1
ENSMUST00000000326.5
Bcl6b

B cell CLL/lymphoma 6, member B

chr7_+_5056706 1.682 ENSMUST00000144802.1
Ccdc106
coiled-coil domain containing 106
chr19_+_8664005 1.622 ENSMUST00000035444.3
ENSMUST00000163785.1
Chrm1

cholinergic receptor, muscarinic 1, CNS

chr7_-_98178254 1.617 ENSMUST00000040971.7
Capn5
calpain 5
chr18_-_74961252 1.611 ENSMUST00000066532.4
Lipg
lipase, endothelial
chr2_+_92599671 1.570 ENSMUST00000065797.6
Chst1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr15_+_77084367 1.505 ENSMUST00000181870.1
1700109K24Rik
RIKEN cDNA 1700109K24 gene
chr4_-_129121699 1.474 ENSMUST00000135763.1
ENSMUST00000149763.1
ENSMUST00000164649.1
Hpca


hippocalcin


chr5_-_99729039 1.468 ENSMUST00000146396.1
ENSMUST00000161148.1
ENSMUST00000161516.1
A930011G23Rik


RIKEN cDNA A930011G23 gene


chr3_+_96181151 1.452 ENSMUST00000035371.8
Sv2a
synaptic vesicle glycoprotein 2 a
chr4_+_152338619 1.446 ENSMUST00000030775.5
ENSMUST00000164662.1
Chd5

chromodomain helicase DNA binding protein 5

chr7_-_78578308 1.412 ENSMUST00000039431.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr17_-_46890405 1.367 ENSMUST00000086675.3
A330017A19Rik
RIKEN cDNA A330017A19 gene
chr11_+_103133303 1.365 ENSMUST00000107037.1
Hexim2
hexamethylene bis-acetamide inducible 2
chr13_-_8038106 1.355 ENSMUST00000165220.2
Gm9742
predicted gene 9742
chr4_+_152338887 1.347 ENSMUST00000005175.4
Chd5
chromodomain helicase DNA binding protein 5
chr3_+_55461758 1.338 ENSMUST00000070418.4
Dclk1
doublecortin-like kinase 1
chr17_-_32788284 1.338 ENSMUST00000159086.2
Zfp871
zinc finger protein 871
chr4_-_129121889 1.325 ENSMUST00000139450.1
ENSMUST00000125931.1
ENSMUST00000116444.2
Hpca


hippocalcin


chr7_+_44590886 1.322 ENSMUST00000107906.3
Kcnc3
potassium voltage gated channel, Shaw-related subfamily, member 3
chr10_+_112172540 1.314 ENSMUST00000132994.1
Caps2
calcyphosphine 2
chrX_+_7919816 1.303 ENSMUST00000041096.3
Pcsk1n
proprotein convertase subtilisin/kexin type 1 inhibitor
chr12_-_90738438 1.287 ENSMUST00000082432.3
Dio2
deiodinase, iodothyronine, type II
chr11_+_103133333 1.263 ENSMUST00000124928.1
ENSMUST00000062530.4
Hexim2

hexamethylene bis-acetamide inducible 2

chr5_-_120588613 1.233 ENSMUST00000046426.8
Tpcn1
two pore channel 1
chr6_+_4902913 1.228 ENSMUST00000175889.1
ENSMUST00000168998.2
Ppp1r9a

protein phosphatase 1, regulatory (inhibitor) subunit 9A

chr2_-_45112890 1.222 ENSMUST00000076836.6
Zeb2
zinc finger E-box binding homeobox 2
chr6_-_97487801 1.221 ENSMUST00000113353.1
ENSMUST00000032146.7
Frmd4b

FERM domain containing 4B

chr2_-_31116289 1.204 ENSMUST00000149196.1
Fnbp1
formin binding protein 1
chr14_+_70555900 1.197 ENSMUST00000163060.1
Hr
hairless
chr3_-_89245005 1.174 ENSMUST00000107464.1
Trim46
tripartite motif-containing 46
chr10_+_81628570 1.155 ENSMUST00000153573.1
ENSMUST00000119336.1
Ankrd24

ankyrin repeat domain 24

chr10_-_118868903 1.139 ENSMUST00000004281.8
Dyrk2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr6_+_48739039 1.128 ENSMUST00000054368.4
ENSMUST00000140054.1
Gimap1

GTPase, IMAP family member 1

chr19_+_27217011 1.123 ENSMUST00000164746.1
ENSMUST00000172302.1
Vldlr

very low density lipoprotein receptor

chr3_+_156561950 1.122 ENSMUST00000041425.5
ENSMUST00000106065.1
Negr1

neuronal growth regulator 1

chr9_+_54698859 1.116 ENSMUST00000120452.1
Dnaja4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr9_-_79718518 1.088 ENSMUST00000071750.6
Col12a1
collagen, type XII, alpha 1
chr3_-_32616479 1.083 ENSMUST00000108234.1
ENSMUST00000155737.1
Gnb4

guanine nucleotide binding protein (G protein), beta 4

chr9_+_110333402 1.082 ENSMUST00000133114.1
ENSMUST00000125759.1
Scap

SREBF chaperone

chr2_-_181135220 1.072 ENSMUST00000016491.7
Kcnq2
potassium voltage-gated channel, subfamily Q, member 2
chr16_-_93794882 1.068 ENSMUST00000180967.1
2310043M15Rik
RIKEN cDNA 2310043M15 gene
chr9_-_79718631 1.067 ENSMUST00000180083.1
Col12a1
collagen, type XII, alpha 1
chr6_-_29507946 1.064 ENSMUST00000101614.3
ENSMUST00000078112.6
Kcp

kielin/chordin-like protein

chr2_-_45113216 1.051 ENSMUST00000124942.1
Zeb2
zinc finger E-box binding homeobox 2
chr9_+_110333276 1.046 ENSMUST00000125823.1
ENSMUST00000131328.1
Scap

SREBF chaperone

chr8_+_25911670 1.023 ENSMUST00000120653.1
ENSMUST00000126226.1
Kcnu1

potassium channel, subfamily U, member 1

chr15_-_88978958 1.018 ENSMUST00000042594.6
ENSMUST00000109368.1
Mlc1

megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human)

chr19_+_27217357 1.015 ENSMUST00000047645.6
ENSMUST00000167487.1
Vldlr

very low density lipoprotein receptor

chr9_-_79718720 1.009 ENSMUST00000121227.1
Col12a1
collagen, type XII, alpha 1
chr6_-_128124312 1.006 ENSMUST00000127105.1
Tspan9
tetraspanin 9
chr3_-_89160155 0.978 ENSMUST00000029686.3
Hcn3
hyperpolarization-activated, cyclic nucleotide-gated K+ 3
chr12_-_98577940 0.967 ENSMUST00000110113.1
Kcnk10
potassium channel, subfamily K, member 10
chr15_-_81960851 0.966 ENSMUST00000071462.6
ENSMUST00000023112.5
Pmm1

phosphomannomutase 1

chr2_-_45113255 0.958 ENSMUST00000068415.4
ENSMUST00000127520.1
Zeb2

zinc finger E-box binding homeobox 2

chr5_+_123252087 0.957 ENSMUST00000121964.1
Wdr66
WD repeat domain 66
chr9_+_3532295 0.943 ENSMUST00000115733.1
Gucy1a2
guanylate cyclase 1, soluble, alpha 2
chr6_+_141249161 0.934 ENSMUST00000043259.7
Pde3a
phosphodiesterase 3A, cGMP inhibited
chr3_-_89245829 0.933 ENSMUST00000041022.8
Trim46
tripartite motif-containing 46
chr9_+_51765325 0.928 ENSMUST00000065496.5
Arhgap20
Rho GTPase activating protein 20
chr12_+_24974914 0.924 ENSMUST00000066652.5
Kidins220
kinase D-interacting substrate 220
chr3_+_97628804 0.920 ENSMUST00000107050.1
ENSMUST00000029729.8
ENSMUST00000107049.1
Fmo5


flavin containing monooxygenase 5


chr10_-_13868779 0.913 ENSMUST00000105534.3
Aig1
androgen-induced 1
chr15_-_102257306 0.902 ENSMUST00000135466.1
Rarg
retinoic acid receptor, gamma
chr18_-_79109391 0.889 ENSMUST00000025430.8
ENSMUST00000161465.2
Setbp1

SET binding protein 1

chr7_-_44929410 0.885 ENSMUST00000107857.3
ENSMUST00000085399.6
ENSMUST00000167930.1
ENSMUST00000166972.1
Ap2a1



adaptor-related protein complex 2, alpha 1 subunit



chr13_+_94358943 0.880 ENSMUST00000022196.3
Ap3b1
adaptor-related protein complex 3, beta 1 subunit
chrX_+_150547375 0.876 ENSMUST00000066337.6
ENSMUST00000112715.1
Alas2

aminolevulinic acid synthase 2, erythroid

chr2_+_29965560 0.873 ENSMUST00000113717.1
ENSMUST00000113719.2
ENSMUST00000100225.2
ENSMUST00000113741.1
ENSMUST00000095083.4
ENSMUST00000046257.7
Sptan1





spectrin alpha, non-erythrocytic 1





chr13_+_76579670 0.858 ENSMUST00000126960.1
ENSMUST00000109583.2
Mctp1

multiple C2 domains, transmembrane 1

chr15_+_25414175 0.855 ENSMUST00000069992.5
Gm5468
predicted gene 5468
chr12_-_16589743 0.845 ENSMUST00000111067.2
ENSMUST00000067124.5
Lpin1

lipin 1

chr6_-_119848059 0.845 ENSMUST00000184864.1
Erc1
ELKS/RAB6-interacting/CAST family member 1
chr4_-_15149755 0.838 ENSMUST00000108273.1
Necab1
N-terminal EF-hand calcium binding protein 1
chr6_+_4903350 0.836 ENSMUST00000175962.1
Ppp1r9a
protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr11_+_79591120 0.830 ENSMUST00000017783.6
Rab11fip4
RAB11 family interacting protein 4 (class II)
chr17_+_37002527 0.827 ENSMUST00000174747.1
Zfp57
zinc finger protein 57
chr15_+_76246747 0.819 ENSMUST00000023225.6
Grina
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr15_+_84680974 0.811 ENSMUST00000065499.4
Prr5
proline rich 5 (renal)
chr15_-_102257449 0.804 ENSMUST00000043172.8
Rarg
retinoic acid receptor, gamma
chr15_+_98092569 0.803 ENSMUST00000163507.1
Pfkm
phosphofructokinase, muscle
chr2_+_145167706 0.801 ENSMUST00000110007.1
Slc24a3
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr7_+_46033698 0.788 ENSMUST00000033121.6
Nomo1
nodal modulator 1
chr8_+_129118043 0.757 ENSMUST00000108744.1
1700008F21Rik
RIKEN cDNA 1700008F21 gene
chrX_+_73192222 0.755 ENSMUST00000101486.4
Xlr3b
X-linked lymphocyte-regulated 3B
chr7_+_5057161 0.751 ENSMUST00000045543.5
Ccdc106
coiled-coil domain containing 106
chr15_-_101850778 0.750 ENSMUST00000023790.3
Krt1
keratin 1
chr2_-_156392829 0.741 ENSMUST00000088578.2
2900097C17Rik
RIKEN cDNA 2900097C17 gene
chrX_+_42067876 0.738 ENSMUST00000126375.1
Xiap
X-linked inhibitor of apoptosis
chr2_+_67413725 0.735 ENSMUST00000178898.1
Gm21830
predicted gene, 21830
chr5_-_124425572 0.735 ENSMUST00000168651.1
Sbno1
sno, strawberry notch homolog 1 (Drosophila)
chr9_+_77921908 0.732 ENSMUST00000133757.1
Elovl5
ELOVL family member 5, elongation of long chain fatty acids (yeast)
chr3_+_96596628 0.721 ENSMUST00000058943.7
Ankrd34a
ankyrin repeat domain 34A
chr13_-_94358818 0.721 ENSMUST00000059598.2
Gm9776
predicted gene 9776
chr5_-_147725988 0.717 ENSMUST00000110529.1
ENSMUST00000031652.3
ENSMUST00000031653.5
Flt1


FMS-like tyrosine kinase 1


chr10_+_81628702 0.717 ENSMUST00000129622.1
Ankrd24
ankyrin repeat domain 24
chr7_+_44428938 0.716 ENSMUST00000127790.1
Lrrc4b
leucine rich repeat containing 4B
chr1_-_133025330 0.705 ENSMUST00000067429.3
ENSMUST00000067398.6
Mdm4

transformed mouse 3T3 cell double minute 4

chr7_-_142576492 0.697 ENSMUST00000140716.1
H19
H19 fetal liver mRNA
chr9_-_22208546 0.693 ENSMUST00000167359.1
1810064F22Rik
RIKEN cDNA 1810064F22 gene
chr8_+_76902277 0.691 ENSMUST00000109912.1
ENSMUST00000128862.1
ENSMUST00000109911.1
Nr3c2


nuclear receptor subfamily 3, group C, member 2


chr15_+_98708187 0.687 ENSMUST00000003444.4
Ccdc65
coiled-coil domain containing 65
chr14_-_64949632 0.681 ENSMUST00000176832.1
Hmbox1
homeobox containing 1
chr11_-_118212715 0.677 ENSMUST00000106302.2
ENSMUST00000151165.1
Cyth1

cytohesin 1

chr5_-_103211251 0.668 ENSMUST00000060871.5
ENSMUST00000112846.1
ENSMUST00000170792.1
ENSMUST00000112847.2
Mapk10



mitogen-activated protein kinase 10



chr5_-_96164147 0.666 ENSMUST00000137207.1
Cnot6l
CCR4-NOT transcription complex, subunit 6-like
chr17_+_6106880 0.661 ENSMUST00000149756.1
Tulp4
tubby like protein 4
chr19_+_4855129 0.660 ENSMUST00000119694.1
Ctsf
cathepsin F
chr14_+_32159865 0.655 ENSMUST00000163336.1
ENSMUST00000169722.1
ENSMUST00000168385.1
Ncoa4


nuclear receptor coactivator 4


chr4_-_15149051 0.652 ENSMUST00000041606.7
Necab1
N-terminal EF-hand calcium binding protein 1
chr4_-_141598206 0.645 ENSMUST00000131317.1
ENSMUST00000006381.4
ENSMUST00000129602.1
Fblim1


filamin binding LIM protein 1


chr8_+_69808672 0.644 ENSMUST00000036074.8
ENSMUST00000123453.1
Gmip

Gem-interacting protein

chr6_+_29396665 0.641 ENSMUST00000096084.5
Ccdc136
coiled-coil domain containing 136
chr7_-_142578093 0.636 ENSMUST00000149974.1
ENSMUST00000152754.1
H19

H19 fetal liver mRNA

chr4_+_43441939 0.626 ENSMUST00000060864.6
Tesk1
testis specific protein kinase 1
chr4_-_43010226 0.622 ENSMUST00000030165.4
Fancg
Fanconi anemia, complementation group G
chr14_-_16249154 0.620 ENSMUST00000148121.1
ENSMUST00000112624.1
Oxsm

3-oxoacyl-ACP synthase, mitochondrial

chr5_-_111761697 0.617 ENSMUST00000129146.1
ENSMUST00000137398.1
ENSMUST00000129065.1
E130006D01Rik


RIKEN cDNA E130006D01 gene


chr2_+_140395309 0.616 ENSMUST00000110067.1
ENSMUST00000110064.1
ENSMUST00000110063.1
ENSMUST00000110062.1
ENSMUST00000078027.5
ENSMUST00000043836.7
Macrod2





MACRO domain containing 2





chr18_+_23753708 0.615 ENSMUST00000115830.1
Mapre2
microtubule-associated protein, RP/EB family, member 2
chr10_-_13868932 0.614 ENSMUST00000019942.5
ENSMUST00000162610.1
Aig1

androgen-induced 1

chr7_-_105633479 0.613 ENSMUST00000147044.1
ENSMUST00000106791.1
Trim3

tripartite motif-containing 3

chr5_-_108674753 0.607 ENSMUST00000119270.1
ENSMUST00000163328.1
ENSMUST00000136227.1
Slc26a1


solute carrier family 26 (sulfate transporter), member 1


chr8_+_26977336 0.600 ENSMUST00000154256.1
ENSMUST00000127097.1
Zfp703

zinc finger protein 703

chr17_+_35823509 0.598 ENSMUST00000173493.1
ENSMUST00000173147.1
ENSMUST00000172846.1
Flot1


flotillin 1


chr1_-_162859684 0.597 ENSMUST00000131058.1
Fmo1
flavin containing monooxygenase 1
chr4_-_151108454 0.596 ENSMUST00000105670.1
Camta1
calmodulin binding transcription activator 1
chr7_-_138846202 0.594 ENSMUST00000118810.1
ENSMUST00000075667.4
ENSMUST00000119664.1
Mapk1ip1


mitogen-activated protein kinase 1 interacting protein 1


chr6_-_99435345 0.588 ENSMUST00000113322.2
ENSMUST00000176850.1
ENSMUST00000176632.1
Foxp1


forkhead box P1


chr11_-_116086929 0.579 ENSMUST00000074628.6
ENSMUST00000106444.3
Wbp2

WW domain binding protein 2

chr17_+_37002482 0.573 ENSMUST00000172527.1
Zfp57
zinc finger protein 57
chr5_+_140735526 0.573 ENSMUST00000120630.2
Amz1
archaelysin family metallopeptidase 1
chr4_-_82505274 0.572 ENSMUST00000050872.8
ENSMUST00000064770.2
Nfib

nuclear factor I/B

chr17_+_37002610 0.570 ENSMUST00000173921.1
ENSMUST00000172580.1
Zfp57

zinc finger protein 57

chr2_-_125506385 0.570 ENSMUST00000028633.6
Fbn1
fibrillin 1
chr2_-_160872985 0.566 ENSMUST00000109460.1
ENSMUST00000127201.1
Zhx3

zinc fingers and homeoboxes 3

chr18_-_64489042 0.564 ENSMUST00000025484.7
Fech
ferrochelatase
chr4_+_62286441 0.556 ENSMUST00000084530.2
Slc31a2
solute carrier family 31, member 2
chr2_-_65567505 0.555 ENSMUST00000100069.2
Scn3a
sodium channel, voltage-gated, type III, alpha
chr7_-_30044734 0.539 ENSMUST00000077787.7
Zfp14
zinc finger protein 14
chr3_+_35754121 0.537 ENSMUST00000108186.1
ENSMUST00000029257.8
Atp11b

ATPase, class VI, type 11B

chr2_-_65567465 0.536 ENSMUST00000066432.5
Scn3a
sodium channel, voltage-gated, type III, alpha
chr2_-_45117349 0.532 ENSMUST00000176438.2
Zeb2
zinc finger E-box binding homeobox 2
chr15_-_83510793 0.528 ENSMUST00000154401.1
Ttll1
tubulin tyrosine ligase-like 1
chr5_-_34187670 0.528 ENSMUST00000042701.6
ENSMUST00000119171.1
Mxd4

Max dimerization protein 4

chr7_-_142578139 0.524 ENSMUST00000136359.1
H19
H19 fetal liver mRNA
chr17_-_30576241 0.520 ENSMUST00000079924.5
ENSMUST00000168787.1
Btbd9

BTB (POZ) domain containing 9

chr14_+_75131499 0.515 ENSMUST00000125833.1
ENSMUST00000124499.1
Lcp1

lymphocyte cytosolic protein 1

chr17_+_56326045 0.513 ENSMUST00000139679.1
ENSMUST00000025036.4
ENSMUST00000086835.5
Kdm4b


lysine (K)-specific demethylase 4B


chr5_+_43672289 0.512 ENSMUST00000156034.1
Cc2d2a
coiled-coil and C2 domain containing 2A
chr5_+_65764073 0.511 ENSMUST00000138239.1
ENSMUST00000087264.3
N4bp2

NEDD4 binding protein 2

chr1_-_87510306 0.506 ENSMUST00000027477.8
Ngef
neuronal guanine nucleotide exchange factor
chr7_+_6415164 0.503 ENSMUST00000160218.1
Smim17
small integral membrane protein 17
chr17_+_37002574 0.499 ENSMUST00000173588.1
Zfp57
zinc finger protein 57
chr6_+_4903298 0.492 ENSMUST00000035813.2
Ppp1r9a
protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr18_-_34373313 0.489 ENSMUST00000006027.5
Reep5
receptor accessory protein 5
chr4_+_101419696 0.487 ENSMUST00000131397.1
ENSMUST00000133055.1
Ak4

adenylate kinase 4

chr7_+_127777095 0.487 ENSMUST00000144406.1
Setd1a
SET domain containing 1A
chr5_+_113735782 0.486 ENSMUST00000065698.5
Ficd
FIC domain containing
chr15_-_85503227 0.486 ENSMUST00000178942.1
7530416G11Rik
RIKEN cDNA 7530416G11 gene
chr6_+_118066356 0.485 ENSMUST00000164960.1
Rasgef1a
RasGEF domain family, member 1A
chr11_-_50827681 0.482 ENSMUST00000109135.2
Zfp354c
zinc finger protein 354C
chrX_+_47912387 0.479 ENSMUST00000001202.8
ENSMUST00000115020.1
Ocrl

oculocerebrorenal syndrome of Lowe

chr1_-_166409773 0.477 ENSMUST00000135673.1
ENSMUST00000079972.6
ENSMUST00000169324.1
ENSMUST00000111411.2
ENSMUST00000128861.1
Pogk




pogo transposable element with KRAB domain




chr6_-_119848120 0.476 ENSMUST00000183703.1
ENSMUST00000183911.1
Erc1

ELKS/RAB6-interacting/CAST family member 1

chr5_+_136919137 0.465 ENSMUST00000181045.1
4933404O12Rik
RIKEN cDNA 4933404O12 gene
chr14_+_32321987 0.462 ENSMUST00000022480.7
Ogdhl
oxoglutarate dehydrogenase-like
chr1_+_59912972 0.456 ENSMUST00000036540.5
Fam117b
family with sequence similarity 117, member B
chr3_+_98382538 0.455 ENSMUST00000178372.1
Zfp697
zinc finger protein 697
chr6_+_29396576 0.454 ENSMUST00000115275.1
Ccdc136
coiled-coil domain containing 136

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.8 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.9 2.8 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.9 2.6 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.6 3.8 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.5 1.4 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.4 2.2 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.4 2.1 GO:0034436 glycoprotein transport(GO:0034436)
0.4 1.7 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.4 1.6 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.4 2.8 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.3 1.0 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.3 1.6 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.3 1.0 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.3 0.9 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.3 0.9 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.3 7.1 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.3 0.8 GO:0006642 triglyceride mobilization(GO:0006642)
0.3 2.1 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.3 1.3 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460)
0.2 1.0 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.2 0.9 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.2 2.2 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.2 1.1 GO:0046684 response to pyrethroid(GO:0046684)
0.2 2.6 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 1.6 GO:0006012 galactose metabolic process(GO:0006012)
0.2 0.6 GO:1903011 negative regulation of bone development(GO:1903011)
0.2 1.9 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.2 3.8 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.2 2.8 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.2 0.7 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.2 0.9 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.1 0.3 GO:0045963 negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963)
0.1 1.9 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.1 0.6 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 0.5 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.1 0.4 GO:0045359 positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.1 0.8 GO:0061622 glycolytic process through glucose-1-phosphate(GO:0061622)
0.1 0.4 GO:0046077 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) deoxyribonucleoside diphosphate biosynthetic process(GO:0009189) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.1 0.3 GO:0051884 regulation of anagen(GO:0051884)
0.1 0.6 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.1 0.4 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.1 0.9 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.1 0.4 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.7 GO:0048597 post-embryonic camera-type eye morphogenesis(GO:0048597)
0.1 0.5 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1 1.0 GO:0071397 cellular response to cholesterol(GO:0071397)
0.1 0.6 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.1 0.7 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.3 GO:0014891 striated muscle atrophy(GO:0014891)
0.1 0.7 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.3 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.1 0.8 GO:0070314 G1 to G0 transition(GO:0070314)
0.1 0.6 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.1 2.0 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 0.2 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.1 1.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.1 0.3 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 0.3 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1 0.3 GO:0002554 serotonin secretion by platelet(GO:0002554) interleukin-3 production(GO:0032632) beta selection(GO:0043366)
0.1 0.4 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 1.0 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 1.3 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.1 0.3 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.1 0.7 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.1 2.2 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 2.7 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.1 0.8 GO:0038203 TORC2 signaling(GO:0038203)
0.1 1.7 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 0.4 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
0.1 0.4 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.1 0.3 GO:0060468 prevention of polyspermy(GO:0060468)
0.1 0.8 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.6 GO:0019532 oxalate transport(GO:0019532)
0.1 0.5 GO:0042748 circadian sleep/wake cycle, non-REM sleep(GO:0042748)
0.1 0.5 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 0.2 GO:0045869 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045869)
0.1 1.1 GO:0001675 acrosome assembly(GO:0001675)
0.1 0.2 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 0.2 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.1 4.2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 0.3 GO:1903028 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.1 3.7 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1 0.9 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.1 1.1 GO:0060081 membrane hyperpolarization(GO:0060081)
0.1 0.7 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 0.3 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.1 0.5 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.1 0.3 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 0.7 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 1.2 GO:0042092 type 2 immune response(GO:0042092)
0.1 1.3 GO:0016486 peptide hormone processing(GO:0016486)
0.1 0.6 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.1 2.4 GO:0061512 protein localization to cilium(GO:0061512)
0.1 0.6 GO:0061470 interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619)
0.1 0.4 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.6 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.1 0.3 GO:0032329 serine transport(GO:0032329)
0.1 0.6 GO:0009404 toxin metabolic process(GO:0009404)
0.1 0.6 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 0.1 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.1 0.6 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.1 1.9 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 0.2 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.1 0.1 GO:1900133 renin secretion into blood stream(GO:0002001) regulation of renin secretion into blood stream(GO:1900133)
0.0 0.7 GO:0003283 atrial septum development(GO:0003283)
0.0 0.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.7 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.2 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 8.2 GO:0051017 actin filament bundle assembly(GO:0051017) actin filament bundle organization(GO:0061572)
0.0 0.4 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.6 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.0 0.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 1.3 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.2 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 4.5 GO:0007098 centrosome cycle(GO:0007098)
0.0 1.2 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.1 GO:0046618 urate transport(GO:0015747) drug export(GO:0046618) negative regulation of intestinal absorption(GO:1904479)
0.0 0.5 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.7 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.8 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.2 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.0 0.3 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.0 GO:0072069 DCT cell differentiation(GO:0072069) metanephric DCT cell differentiation(GO:0072240)
0.0 0.1 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.0 0.4 GO:0010954 positive regulation of protein processing(GO:0010954)
0.0 0.2 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.2 GO:0098909 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.0 0.1 GO:0071267 amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267)
0.0 1.3 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.2 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.2 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.1 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.0 0.3 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.6 GO:0046039 GTP metabolic process(GO:0046039)
0.0 0.4 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0 0.3 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.2 GO:1901032 negative regulation of response to reactive oxygen species(GO:1901032) negative regulation of hydrogen peroxide-induced cell death(GO:1903206)
0.0 0.1 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.4 GO:0051926 negative regulation of calcium ion transport(GO:0051926)
0.0 0.3 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.6 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.1 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.6 GO:0001541 ovarian follicle development(GO:0001541)
0.0 0.4 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.3 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.4 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.4 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.5 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.0 1.1 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0030934 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
1.0 3.8 GO:1990769 proximal neuron projection(GO:1990769)
0.5 2.6 GO:1990761 growth cone lamellipodium(GO:1990761)
0.3 7.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2 2.8 GO:0044327 dendritic spine head(GO:0044327)
0.2 0.8 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.2 1.0 GO:0044316 cone cell pedicle(GO:0044316)
0.2 0.7 GO:0097447 dendritic tree(GO:0097447)
0.2 2.1 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.2 0.9 GO:0032437 cuticular plate(GO:0032437)
0.2 2.2 GO:0016342 catenin complex(GO:0016342)
0.1 0.7 GO:0001533 cornified envelope(GO:0001533)
0.1 1.1 GO:0002080 acrosomal membrane(GO:0002080)
0.1 0.9 GO:0016600 flotillin complex(GO:0016600)
0.1 1.0 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 4.2 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 1.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 0.7 GO:0097342 ripoptosome(GO:0097342)
0.1 0.4 GO:1990462 omegasome(GO:1990462)
0.1 0.4 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 1.6 GO:0032279 asymmetric synapse(GO:0032279)
0.1 1.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 1.1 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.9 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.1 1.5 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.3 GO:0019815 B cell receptor complex(GO:0019815)
0.1 0.4 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 1.6 GO:0009986 cell surface(GO:0009986)
0.1 0.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.9 GO:0032433 filopodium tip(GO:0032433)
0.1 0.7 GO:0097542 ciliary tip(GO:0097542)
0.1 0.8 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.4 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.5 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 1.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.6 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.7 GO:0044754 autolysosome(GO:0044754)
0.0 1.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 1.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.8 GO:0000800 lateral element(GO:0000800)
0.0 0.5 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.6 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 1.0 GO:0005938 cell cortex(GO:0005938)
0.0 1.5 GO:0005604 basement membrane(GO:0005604)
0.0 1.0 GO:0035371 microtubule plus-end(GO:0035371)
0.0 5.0 GO:0005884 actin filament(GO:0005884)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.5 GO:0036038 MKS complex(GO:0036038)
0.0 0.7 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 1.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.0 GO:0005901 caveola(GO:0005901)
0.0 0.6 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 1.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.6 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 1.8 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 3.4 GO:0044306 neuron projection terminus(GO:0044306)
0.0 0.6 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.6 GO:0097440 apical dendrite(GO:0097440)
0.0 0.8 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.4 GO:0034707 chloride channel complex(GO:0034707)
0.0 3.1 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 0.2 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.7 GO:0042641 actomyosin(GO:0042641)
0.0 1.5 GO:0005802 trans-Golgi network(GO:0005802)
0.0 3.1 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 1.4 GO:0005770 late endosome(GO:0005770)
0.0 2.3 GO:0043235 receptor complex(GO:0043235)
0.0 3.0 GO:0000139 Golgi membrane(GO:0000139)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 8.5 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.8 4.8 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.7 2.1 GO:0034437 very-low-density lipoprotein particle binding(GO:0034189) glycoprotein transporter activity(GO:0034437)
0.7 2.8 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.4 1.6 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.3 1.0 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.3 1.6 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.3 1.6 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.3 1.2 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.3 1.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.3 0.9 GO:0016748 succinyltransferase activity(GO:0016748)
0.3 2.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.3 1.4 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.3 0.8 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.2 1.0 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.2 0.9 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.2 0.8 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.2 0.8 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.2 0.6 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.2 0.6 GO:0030350 iron-responsive element binding(GO:0030350)
0.2 3.0 GO:0050811 GABA receptor binding(GO:0050811)
0.2 0.7 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2 2.1 GO:0050897 cobalt ion binding(GO:0050897)
0.2 0.8 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.2 0.6 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.2 4.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.4 GO:0004127 cytidylate kinase activity(GO:0004127) uridylate kinase activity(GO:0009041)
0.1 0.6 GO:1990188 euchromatin binding(GO:1990188)
0.1 0.7 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.1 0.3 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 3.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 4.0 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.7 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.3 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.1 0.5 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 0.3 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.1 0.7 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.3 GO:0036004 GAF domain binding(GO:0036004)
0.1 1.7 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 1.0 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 1.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.4 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 1.1 GO:0031402 sodium ion binding(GO:0031402)
0.1 0.2 GO:0071723 lipopeptide binding(GO:0071723)
0.1 1.0 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 0.8 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 0.3 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.1 1.5 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.6 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 0.4 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.7 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1 0.4 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 0.7 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.3 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 0.5 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 2.3 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 0.5 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.1 0.3 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.6 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.1 0.4 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.0 0.6 GO:0031005 filamin binding(GO:0031005)
0.0 0.4 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.4 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.2 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.0 0.4 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 2.2 GO:0015485 cholesterol binding(GO:0015485)
0.0 2.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.3 GO:0035325 receptor signaling protein tyrosine kinase activity(GO:0004716) Toll-like receptor binding(GO:0035325)
0.0 0.3 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 2.4 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.7 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.1 GO:0051379 epinephrine binding(GO:0051379)
0.0 0.6 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.9 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.9 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.4 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.2 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 1.2 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 1.1 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 4.2 GO:0051015 actin filament binding(GO:0051015)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.5 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.4 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 1.1 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.4 GO:0005267 potassium channel activity(GO:0005267)
0.0 1.0 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.6 GO:0042562 hormone binding(GO:0042562)
0.0 0.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.6 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.7 GO:0030507 spectrin binding(GO:0030507)
0.0 1.4 GO:0030165 PDZ domain binding(GO:0030165)
0.0 3.7 GO:0008017 microtubule binding(GO:0008017)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0070628 proteasome binding(GO:0070628)
0.0 0.2 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 2.3 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 0.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.3 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.1 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.8 GO:0016798 hydrolase activity, acting on glycosyl bonds(GO:0016798)
0.0 0.6 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.3 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.6 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 2.2 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.3 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.3 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.4 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.3 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 4.1 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.1 2.1 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 0.3 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 0.7 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.1 0.6 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 2.2 PID_EPO_PATHWAY EPO signaling pathway
0.0 1.3 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.0 1.5 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.4 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.0 3.3 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 0.3 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.0 0.2 ST_B_CELL_ANTIGEN_RECEPTOR B Cell Antigen Receptor
0.0 1.4 PID_SHP2_PATHWAY SHP2 signaling
0.0 0.9 PID_ARF_3PATHWAY Arf1 pathway
0.0 0.3 PID_NFKAPPAB_ATYPICAL_PATHWAY Atypical NF-kappaB pathway
0.0 1.1 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.0 2.1 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 0.7 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.9 SIG_BCR_SIGNALING_PATHWAY Members of the BCR signaling pathway
0.0 0.4 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.9 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 0.2 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 0.7 PID_PI3KCI_PATHWAY Class I PI3K signaling events
0.0 0.4 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.3 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.4 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.5 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 0.3 SIG_CHEMOTAXIS Genes related to chemotaxis
0.0 0.2 PID_REELIN_PATHWAY Reelin signaling pathway
0.0 0.5 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.2 0.9 REACTOME_ARMS_MEDIATED_ACTIVATION Genes involved in ARMS-mediated activation
0.1 1.0 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 1.7 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 4.5 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.3 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.1 2.2 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.1 5.7 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.1 1.7 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 0.4 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 0.8 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.1 0.3 REACTOME_ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS Genes involved in Activation of NF-kappaB in B Cells
0.1 0.4 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 1.0 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 0.7 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 1.9 REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.1 2.4 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 2.3 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 1.4 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.0 1.3 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.9 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.6 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.4 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.4 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.9 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.9 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.9 REACTOME_KERATAN_SULFATE_BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 1.3 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.0 0.3 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.9 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.5 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.9 REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.6 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.4 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.1 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.2 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.2 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 2.9 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME_REGULATION_OF_SIGNALING_BY_CBL Genes involved in Regulation of signaling by CBL
0.0 0.5 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.5 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.1 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.2 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.1 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism