Motif ID: Foxb1

Z-value: 0.860


Transcription factors associated with Foxb1:

Gene SymbolEntrez IDGene Name
Foxb1 ENSMUSG00000059246.4 Foxb1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxb1mm10_v2_chr9_-_69760924_697609400.076.6e-01Click!


Activity profile for motif Foxb1.

activity profile for motif Foxb1


Sorted Z-values histogram for motif Foxb1

Sorted Z-values for motif Foxb1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxb1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_55782500 5.043 ENSMUST00000075422.4
Mab21l1
mab-21-like 1 (C. elegans)
chr3_-_123672321 5.027 ENSMUST00000172537.1
ENSMUST00000029602.6
Ndst3

N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3

chr10_+_26229707 4.441 ENSMUST00000060716.5
ENSMUST00000164660.1
Samd3

sterile alpha motif domain containing 3

chr1_-_158814469 4.323 ENSMUST00000161589.2
Pappa2
pappalysin 2
chr17_+_93199348 3.542 ENSMUST00000064775.6
Adcyap1
adenylate cyclase activating polypeptide 1
chr2_-_65529275 3.538 ENSMUST00000126837.1
Scn3a
sodium channel, voltage-gated, type III, alpha
chr3_-_123690806 3.323 ENSMUST00000154668.1
Ndst3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr6_-_56362356 3.314 ENSMUST00000044505.7
ENSMUST00000166102.1
ENSMUST00000164037.1
ENSMUST00000114327.2
Pde1c



phosphodiesterase 1C



chr2_+_55437100 3.283 ENSMUST00000112633.2
ENSMUST00000112632.1
Kcnj3

potassium inwardly-rectifying channel, subfamily J, member 3

chr10_+_69925484 3.223 ENSMUST00000182692.1
ENSMUST00000092433.5
Ank3

ankyrin 3, epithelial

chr10_+_69925954 3.150 ENSMUST00000181974.1
ENSMUST00000182795.1
ENSMUST00000182437.1
Ank3


ankyrin 3, epithelial


chr10_+_69925766 3.082 ENSMUST00000182269.1
ENSMUST00000183261.1
ENSMUST00000183074.1
Ank3


ankyrin 3, epithelial


chr19_+_47228804 2.757 ENSMUST00000111807.3
Neurl1a
neuralized homolog 1A (Drosophila)
chr10_+_69925800 2.496 ENSMUST00000182029.1
Ank3
ankyrin 3, epithelial
chr6_+_14901344 2.461 ENSMUST00000115477.1
Foxp2
forkhead box P2
chr18_-_47333311 2.345 ENSMUST00000126684.1
ENSMUST00000156422.1
Sema6a

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A

chr8_+_58912257 2.303 ENSMUST00000160055.1
BC030500
cDNA sequence BC030500
chr1_-_72536930 2.042 ENSMUST00000047786.5
March4
membrane-associated ring finger (C3HC4) 4
chr19_+_20601958 2.004 ENSMUST00000087638.3
Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
chr3_+_76075583 1.947 ENSMUST00000160261.1
Fstl5
follistatin-like 5
chr14_-_93888732 1.927 ENSMUST00000068992.2
Pcdh9
protocadherin 9
chr13_+_5861489 1.852 ENSMUST00000000080.6
Klf6
Kruppel-like factor 6
chr18_+_36952621 1.698 ENSMUST00000115661.2
Pcdha2
protocadherin alpha 2
chr16_-_74411292 1.599 ENSMUST00000117200.1
Robo2
roundabout homolog 2 (Drosophila)
chr3_-_127499095 1.458 ENSMUST00000182594.1
Ank2
ankyrin 2, brain
chr4_-_135494615 1.416 ENSMUST00000102549.3
Nipal3
NIPA-like domain containing 3
chr3_+_96245530 1.391 ENSMUST00000074976.6
Hist2h2aa1
histone cluster 2, H2aa1
chr8_+_66386292 1.370 ENSMUST00000039540.5
ENSMUST00000110253.2
March1

membrane-associated ring finger (C3HC4) 1

chr16_-_34095983 1.336 ENSMUST00000114973.1
ENSMUST00000114964.1
Kalrn

kalirin, RhoGEF kinase

chr7_-_34655500 1.313 ENSMUST00000032709.1
Kctd15
potassium channel tetramerisation domain containing 15
chr10_-_96409038 1.224 ENSMUST00000179683.1
Gm20091
predicted gene, 20091
chr15_-_48791933 1.224 ENSMUST00000160658.1
ENSMUST00000100670.3
ENSMUST00000162830.1
Csmd3


CUB and Sushi multiple domains 3


chr6_+_14901440 1.182 ENSMUST00000128567.1
Foxp2
forkhead box P2
chr5_+_66676098 1.167 ENSMUST00000031131.9
Uchl1
ubiquitin carboxy-terminal hydrolase L1
chr7_+_119900099 1.159 ENSMUST00000106516.1
Lyrm1
LYR motif containing 1
chr1_+_179546303 1.143 ENSMUST00000040706.8
Cnst
consortin, connexin sorting protein
chr3_-_96240317 1.142 ENSMUST00000078756.5
Hist2h2aa2
histone cluster 2, H2aa2
chr2_-_163645125 1.125 ENSMUST00000017851.3
Serinc3
serine incorporator 3
chrX_+_109095359 1.119 ENSMUST00000033598.8
Sh3bgrl
SH3-binding domain glutamic acid-rich protein like
chr5_-_137502402 1.068 ENSMUST00000111035.1
ENSMUST00000031728.4
Pop7

processing of precursor 7, ribonuclease P family, (S. cerevisiae)

chr18_-_43687695 1.008 ENSMUST00000082254.6
Jakmip2
janus kinase and microtubule interacting protein 2
chr2_-_45110336 1.006 ENSMUST00000028229.6
ENSMUST00000152232.1
Zeb2

zinc finger E-box binding homeobox 2

chr2_+_181767283 0.993 ENSMUST00000108757.2
Myt1
myelin transcription factor 1
chr2_+_181767040 0.979 ENSMUST00000108756.1
Myt1
myelin transcription factor 1
chr2_-_59948155 0.897 ENSMUST00000153136.1
Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr10_+_60106452 0.862 ENSMUST00000165024.2
Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr9_-_101198999 0.857 ENSMUST00000066773.7
Ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr4_-_135494499 0.821 ENSMUST00000105856.2
Nipal3
NIPA-like domain containing 3
chr4_+_102430047 0.798 ENSMUST00000172616.1
Pde4b
phosphodiesterase 4B, cAMP specific
chr9_+_47530173 0.786 ENSMUST00000114548.1
ENSMUST00000152459.1
ENSMUST00000143026.1
ENSMUST00000085909.2
ENSMUST00000114547.1
ENSMUST00000034581.3
Cadm1





cell adhesion molecule 1





chr7_+_29071597 0.778 ENSMUST00000180926.1
Gm26604
predicted gene, 26604
chr10_-_49783259 0.758 ENSMUST00000105484.3
ENSMUST00000105486.1
ENSMUST00000079751.2
ENSMUST00000105485.1
Grik2



glutamate receptor, ionotropic, kainate 2 (beta 2)



chr19_-_28911879 0.750 ENSMUST00000179171.1
AC163993.1
AC163993.1
chrX_-_43274786 0.725 ENSMUST00000016294.7
Tenm1
teneurin transmembrane protein 1
chr3_+_136670076 0.714 ENSMUST00000070198.7
Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr3_-_33082004 0.712 ENSMUST00000108225.3
Pex5l
peroxisomal biogenesis factor 5-like
chr1_+_179961110 0.699 ENSMUST00000076687.5
ENSMUST00000097450.3
Cdc42bpa

CDC42 binding protein kinase alpha

chr1_+_10056922 0.662 ENSMUST00000149214.1
Cspp1
centrosome and spindle pole associated protein 1
chr16_+_44394771 0.650 ENSMUST00000099742.2
Wdr52
WD repeat domain 52
chr6_+_34709610 0.647 ENSMUST00000031775.6
Cald1
caldesmon 1
chrX_+_41401128 0.597 ENSMUST00000115103.2
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr10_-_61979073 0.587 ENSMUST00000105453.1
ENSMUST00000105452.2
ENSMUST00000105454.2
Col13a1


collagen, type XIII, alpha 1


chr1_+_179960472 0.538 ENSMUST00000097453.2
ENSMUST00000111117.1
Cdc42bpa

CDC42 binding protein kinase alpha

chrX_-_94123087 0.536 ENSMUST00000113925.1
Zfx
zinc finger protein X-linked
chr3_+_134236483 0.518 ENSMUST00000181904.1
ENSMUST00000053048.9
Cxxc4

CXXC finger 4

chr6_+_8948608 0.512 ENSMUST00000160300.1
Nxph1
neurexophilin 1
chr11_-_98329641 0.437 ENSMUST00000041685.6
Neurod2
neurogenic differentiation 2
chr13_-_100616911 0.431 ENSMUST00000168772.1
ENSMUST00000163163.1
ENSMUST00000022137.7
Marveld2


MARVEL (membrane-associating) domain containing 2


chr17_+_34969912 0.426 ENSMUST00000173680.1
Gm20481
predicted gene 20481
chr6_-_3494587 0.418 ENSMUST00000049985.8
Hepacam2
HEPACAM family member 2
chr9_+_53850243 0.324 ENSMUST00000048485.5
Sln
sarcolipin
chr1_+_81077204 0.305 ENSMUST00000123720.1
Nyap2
neuronal tyrosine-phophorylated phosphoinositide 3-kinase adaptor 2
chr1_-_179546261 0.285 ENSMUST00000027769.5
Tfb2m
transcription factor B2, mitochondrial
chr7_+_24271568 0.279 ENSMUST00000032696.6
Zfp93
zinc finger protein 93
chr1_-_181211437 0.267 ENSMUST00000162963.1
ENSMUST00000162819.1
Wdr26

WD repeat domain 26

chr11_-_17008647 0.258 ENSMUST00000102881.3
Plek
pleckstrin
chr1_-_170867761 0.242 ENSMUST00000027974.6
Atf6
activating transcription factor 6
chr2_-_176917518 0.209 ENSMUST00000108931.2
Gm14296
predicted gene 14296
chr4_-_139832920 0.204 ENSMUST00000174681.1
Pax7
paired box gene 7
chrX_+_101376359 0.196 ENSMUST00000119080.1
Gjb1
gap junction protein, beta 1
chr15_+_85116829 0.176 ENSMUST00000105085.1
Gm10923
predicted gene 10923
chr5_+_143817786 0.170 ENSMUST00000100487.4
Eif2ak1
eukaryotic translation initiation factor 2 alpha kinase 1
chr9_-_67049143 0.167 ENSMUST00000113687.1
ENSMUST00000113693.1
ENSMUST00000113701.1
ENSMUST00000034928.5
ENSMUST00000113685.3
ENSMUST00000030185.4
ENSMUST00000050905.9
ENSMUST00000113705.1
ENSMUST00000113697.1
ENSMUST00000113707.2
Tpm1









tropomyosin 1, alpha









chr3_-_146781351 0.154 ENSMUST00000005164.7
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr4_-_139833524 0.142 ENSMUST00000030508.7
Pax7
paired box gene 7
chr13_+_40859768 0.127 ENSMUST00000110191.2
Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr1_+_43445736 0.121 ENSMUST00000086421.5
ENSMUST00000114744.1
Nck2

non-catalytic region of tyrosine kinase adaptor protein 2

chr6_+_92940572 0.103 ENSMUST00000181145.1
ENSMUST00000181840.1
9530026P05Rik

RIKEN cDNA 9530026P05 gene

chr12_-_101958148 0.100 ENSMUST00000159883.1
ENSMUST00000160251.1
ENSMUST00000161011.1
ENSMUST00000021606.5
Atxn3



ataxin 3



chr12_-_31950535 0.095 ENSMUST00000172314.2
Hbp1
high mobility group box transcription factor 1
chr11_-_107348130 0.095 ENSMUST00000134763.1
Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chr10_+_37139558 0.095 ENSMUST00000062667.3
5930403N24Rik
RIKEN cDNA 5930403N24 gene
chrX_+_150594420 0.081 ENSMUST00000112713.2
Pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr12_-_84450944 0.075 ENSMUST00000085192.5
Aldh6a1
aldehyde dehydrogenase family 6, subfamily A1
chr2_-_160859601 0.067 ENSMUST00000103112.1
Zhx3
zinc fingers and homeoboxes 3
chr1_+_19208914 0.065 ENSMUST00000027059.4
Tfap2b
transcription factor AP-2 beta
chr15_+_43477213 0.061 ENSMUST00000022962.6
Emc2
ER membrane protein complex subunit 2
chr13_-_12464925 0.061 ENSMUST00000124888.1
Lgals8
lectin, galactose binding, soluble 8
chrX_+_119927196 0.058 ENSMUST00000040961.2
ENSMUST00000113366.1
Pabpc5

poly(A) binding protein, cytoplasmic 5

chr8_+_93810832 0.023 ENSMUST00000034198.8
ENSMUST00000125716.1
Gnao1

guanine nucleotide binding protein, alpha O


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 8.3 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
1.2 3.5 GO:0071649 negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865) regulation of chemokine (C-C motif) ligand 5 production(GO:0071649) positive regulation of somatostatin secretion(GO:0090274)
1.1 12.0 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.7 3.5 GO:0046684 response to pyrethroid(GO:0046684)
0.5 1.6 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.5 2.0 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.5 3.3 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.4 1.1 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.3 2.8 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.3 1.2 GO:0007412 axon target recognition(GO:0007412)
0.3 0.9 GO:0007525 somatic muscle development(GO:0007525)
0.3 1.1 GO:0009597 detection of virus(GO:0009597)
0.3 0.8 GO:0009826 unidimensional cell growth(GO:0009826) susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.2 0.7 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) regulation of connective tissue replacement(GO:1905203)
0.2 3.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.2 2.0 GO:0060539 diaphragm development(GO:0060539)
0.2 1.0 GO:1903056 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.2 1.3 GO:0061368 maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.2 2.0 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.2 1.5 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1 0.4 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.1 2.2 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.7 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1 0.9 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 2.3 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 1.1 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 0.3 GO:1901894 regulation of calcium-transporting ATPase activity(GO:1901894)
0.1 1.4 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 0.8 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 0.3 GO:0010920 negative regulation of inositol phosphate biosynthetic process(GO:0010920)
0.1 0.8 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 1.2 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.3 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 4.9 GO:0060349 bone morphogenesis(GO:0060349)
0.0 0.5 GO:0060746 parental behavior(GO:0060746)
0.0 0.3 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.2 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.1 GO:1903898 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.0 0.2 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.1 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.0 2.5 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.1 GO:0097274 urea homeostasis(GO:0097274)
0.0 0.7 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.2 GO:0015868 purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)
0.0 0.2 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.7 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.2 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.6 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 0.6 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.0 3.8 GO:0043010 camera-type eye development(GO:0043010)
0.0 0.4 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.1 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 12.0 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.2 3.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.2 1.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.2 0.7 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 0.8 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 0.7 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.6 GO:0030478 actin cap(GO:0030478)
0.1 0.4 GO:0061689 paranodal junction(GO:0033010) tricellular tight junction(GO:0061689)
0.1 1.5 GO:0031430 M band(GO:0031430)
0.1 0.8 GO:0070852 cell body fiber(GO:0070852)
0.1 2.5 GO:0097440 apical dendrite(GO:0097440)
0.1 1.6 GO:0030673 axolemma(GO:0030673)
0.0 3.3 GO:0030315 T-tubule(GO:0030315)
0.0 1.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.6 GO:0043083 synaptic cleft(GO:0043083)
0.0 3.5 GO:0043195 terminal bouton(GO:0043195)
0.0 0.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 1.9 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 0.1 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0 0.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 2.0 GO:0005795 Golgi stack(GO:0005795)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 2.3 GO:0030424 axon(GO:0030424)
0.0 1.2 GO:0044306 neuron projection terminus(GO:0044306)
0.0 1.2 GO:0042641 actomyosin(GO:0042641)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 8.3 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.7 3.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.5 3.3 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.4 2.0 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.3 1.2 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.2 13.4 GO:0030507 spectrin binding(GO:0030507)
0.2 3.6 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.2 1.6 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 3.5 GO:0031402 sodium ion binding(GO:0031402)
0.1 0.7 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 1.1 GO:0071253 connexin binding(GO:0071253)
0.1 0.8 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 2.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.7 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 2.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.6 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 1.1 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 1.1 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 0.3 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 2.8 GO:0045182 translation regulator activity(GO:0045182)
0.1 1.4 GO:0042287 MHC protein binding(GO:0042287)
0.0 4.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 1.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 5.0 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.0 0.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.0 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.4 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.4 GO:0070888 E-box binding(GO:0070888)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.3 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.3 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 1.2 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 1.2 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 3.9 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.9 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 2.4 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.2 PID_CDC42_PATHWAY CDC42 signaling events
0.0 0.6 NABA_COLLAGENS Genes encoding collagen proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.3 12.0 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.3 4.3 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 8.3 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.2 3.3 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 2.3 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.1 3.5 REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 1.7 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.8 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.7 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.6 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.8 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.8 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.3 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly