Motif ID: Insm1

Z-value: 0.490


Transcription factors associated with Insm1:

Gene SymbolEntrez IDGene Name
Insm1 ENSMUSG00000068154.4 Insm1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Insm1mm10_v2_chr2_+_146221921_1462219210.425.8e-03Click!


Activity profile for motif Insm1.

activity profile for motif Insm1


Sorted Z-values histogram for motif Insm1

Sorted Z-values for motif Insm1



Network of associatons between targets according to the STRING database.



First level regulatory network of Insm1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_156562141 2.461 ENSMUST00000175773.1
Negr1
neuronal growth regulator 1
chr3_+_156561950 2.248 ENSMUST00000041425.5
ENSMUST00000106065.1
Negr1

neuronal growth regulator 1

chr16_-_67620880 1.920 ENSMUST00000114292.1
ENSMUST00000120898.1
Cadm2

cell adhesion molecule 2

chr3_+_156561792 1.694 ENSMUST00000074015.4
Negr1
neuronal growth regulator 1
chr6_+_4902913 1.692 ENSMUST00000175889.1
ENSMUST00000168998.2
Ppp1r9a

protein phosphatase 1, regulatory (inhibitor) subunit 9A

chrX_+_9199865 1.607 ENSMUST00000069763.2
Lancl3
LanC lantibiotic synthetase component C-like 3 (bacterial)
chr4_-_88033328 1.601 ENSMUST00000078090.5
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr16_-_67620805 1.598 ENSMUST00000120594.1
Cadm2
cell adhesion molecule 2
chr13_+_16011851 1.501 ENSMUST00000042603.6
Inhba
inhibin beta-A
chr3_-_73056943 1.450 ENSMUST00000059407.7
Slitrk3
SLIT and NTRK-like family, member 3
chr6_+_4903350 1.419 ENSMUST00000175962.1
Ppp1r9a
protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr14_-_55116935 1.364 ENSMUST00000022819.5
Jph4
junctophilin 4
chr10_-_42276688 1.227 ENSMUST00000175881.1
ENSMUST00000056974.3
Foxo3

forkhead box O3

chr12_+_102948843 1.136 ENSMUST00000101099.5
Unc79
unc-79 homolog (C. elegans)
chr12_+_95692212 1.129 ENSMUST00000057324.3
Flrt2
fibronectin leucine rich transmembrane protein 2
chr12_+_119945957 1.105 ENSMUST00000058644.8
Tmem196
transmembrane protein 196
chr11_-_77894096 1.074 ENSMUST00000017597.4
Pipox
pipecolic acid oxidase
chr17_+_74528467 1.056 ENSMUST00000182944.1
ENSMUST00000182597.1
ENSMUST00000182133.1
ENSMUST00000183224.1
Birc6



baculoviral IAP repeat-containing 6



chr3_+_117575268 1.053 ENSMUST00000039564.6
4833424O15Rik
RIKEN cDNA 4833424O15 gene
chr12_+_37880700 1.048 ENSMUST00000040500.7
Dgkb
diacylglycerol kinase, beta
chr3_+_117575227 0.986 ENSMUST00000106473.2
4833424O15Rik
RIKEN cDNA 4833424O15 gene
chr11_-_70687917 0.977 ENSMUST00000108545.2
ENSMUST00000120261.1
ENSMUST00000036299.7
ENSMUST00000119120.1
ENSMUST00000100933.3
Camta2




calmodulin binding transcription activator 2




chr17_+_74528279 0.938 ENSMUST00000180037.1
ENSMUST00000024879.6
Birc6

baculoviral IAP repeat-containing 6

chr18_+_25168993 0.933 ENSMUST00000036619.7
ENSMUST00000165400.1
ENSMUST00000097643.3
AW554918


expressed sequence AW554918


chr15_-_54919961 0.932 ENSMUST00000167541.2
ENSMUST00000041591.9
ENSMUST00000173516.1
Enpp2


ectonucleotide pyrophosphatase/phosphodiesterase 2


chr6_-_85069449 0.912 ENSMUST00000160783.1
ENSMUST00000160197.1
Exoc6b

exocyst complex component 6B

chr2_+_32609043 0.909 ENSMUST00000128811.1
St6galnac6
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr2_-_127521358 0.897 ENSMUST00000028850.8
ENSMUST00000103215.4
Kcnip3

Kv channel interacting protein 3, calsenilin

chrX_+_99975570 0.845 ENSMUST00000113779.1
ENSMUST00000113776.1
ENSMUST00000113775.1
ENSMUST00000113780.1
ENSMUST00000113778.1
ENSMUST00000113781.1
ENSMUST00000113783.1
ENSMUST00000071453.2
ENSMUST00000113777.1
Eda








ectodysplasin-A








chr7_+_5057161 0.831 ENSMUST00000045543.5
Ccdc106
coiled-coil domain containing 106
chr2_+_11172080 0.817 ENSMUST00000114853.1
Prkcq
protein kinase C, theta
chr18_+_64340225 0.804 ENSMUST00000175965.2
ENSMUST00000115145.3
Onecut2

one cut domain, family member 2

chr8_-_48555846 0.799 ENSMUST00000110345.1
ENSMUST00000110343.1
Tenm3

teneurin transmembrane protein 3

chr10_-_116473418 0.786 ENSMUST00000087965.4
ENSMUST00000164271.1
Kcnmb4

potassium large conductance calcium-activated channel, subfamily M, beta member 4

chr14_-_20794009 0.765 ENSMUST00000100837.3
ENSMUST00000080440.6
ENSMUST00000071816.6
Camk2g


calcium/calmodulin-dependent protein kinase II gamma


chr19_+_44992127 0.761 ENSMUST00000179305.1
Sema4g
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr14_-_74947865 0.728 ENSMUST00000088970.5
Lrch1
leucine-rich repeats and calponin homology (CH) domain containing 1
chrX_+_68678541 0.698 ENSMUST00000088546.5
Fmr1
fragile X mental retardation syndrome 1
chr9_-_44881274 0.681 ENSMUST00000002095.3
ENSMUST00000114689.1
ENSMUST00000128768.1
Kmt2a


lysine (K)-specific methyltransferase 2A


chrX_+_68678624 0.675 ENSMUST00000114656.1
Fmr1
fragile X mental retardation syndrome 1
chr17_+_47688992 0.659 ENSMUST00000156118.1
Frs3
fibroblast growth factor receptor substrate 3
chr7_+_5056706 0.659 ENSMUST00000144802.1
Ccdc106
coiled-coil domain containing 106
chr19_+_4003334 0.640 ENSMUST00000025806.3
Doc2g
double C2, gamma
chr19_+_8664005 0.636 ENSMUST00000035444.3
ENSMUST00000163785.1
Chrm1

cholinergic receptor, muscarinic 1, CNS

chr2_+_52072823 0.630 ENSMUST00000112693.2
ENSMUST00000069794.5
Rif1

Rap1 interacting factor 1 homolog (yeast)

chr7_+_30095150 0.624 ENSMUST00000130526.1
ENSMUST00000108200.1
Zfp260

zinc finger protein 260

chr10_-_116473875 0.619 ENSMUST00000068233.4
Kcnmb4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr16_+_18248866 0.615 ENSMUST00000115640.1
ENSMUST00000140206.1
Trmt2a

TRM2 tRNA methyltransferase 2A

chr5_-_31048014 0.571 ENSMUST00000137223.1
Slc5a6
solute carrier family 5 (sodium-dependent vitamin transporter), member 6
chr16_+_18248961 0.554 ENSMUST00000100099.3
Trmt2a
TRM2 tRNA methyltransferase 2A
chr15_+_30172570 0.547 ENSMUST00000081728.5
Ctnnd2
catenin (cadherin associated protein), delta 2
chr6_+_42286709 0.547 ENSMUST00000163936.1
Clcn1
chloride channel 1
chr11_+_60105079 0.545 ENSMUST00000132012.1
Rai1
retinoic acid induced 1
chr5_+_111417263 0.541 ENSMUST00000094463.4
Mn1
meningioma 1
chr7_+_28766747 0.534 ENSMUST00000170068.1
ENSMUST00000072965.4
Sirt2

sirtuin 2

chr6_+_42286676 0.531 ENSMUST00000031894.6
Clcn1
chloride channel 1
chr13_+_63815240 0.517 ENSMUST00000021926.5
ENSMUST00000095724.3
ENSMUST00000143449.1
ENSMUST00000067821.5
Ercc6l2



excision repair cross-complementing rodent repair deficiency, complementation group 6 like 2



chr9_-_43105718 0.516 ENSMUST00000165665.1
Arhgef12
Rho guanine nucleotide exchange factor (GEF) 12
chr1_+_36511867 0.509 ENSMUST00000001166.7
ENSMUST00000097776.3
Cnnm3

cyclin M3

chr17_+_35517100 0.504 ENSMUST00000164242.2
ENSMUST00000045956.7
Cchcr1

coiled-coil alpha-helical rod protein 1

chr14_+_63606491 0.483 ENSMUST00000119973.2
Xkr6
X Kell blood group precursor related family member 6 homolog
chr5_-_115436508 0.479 ENSMUST00000078701.3
4930430O22Rik
RIKEN cDNA 4930430O22 gene
chr11_+_106084577 0.477 ENSMUST00000002044.9
Map3k3
mitogen-activated protein kinase kinase kinase 3
chr14_+_54625305 0.461 ENSMUST00000097177.4
Psmb11
proteasome (prosome, macropain) subunit, beta type, 11
chr16_-_45724600 0.461 ENSMUST00000096057.4
Tagln3
transgelin 3
chr15_-_54920115 0.454 ENSMUST00000171545.1
Enpp2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr9_+_108808356 0.449 ENSMUST00000035218.7
Nckipsd
NCK interacting protein with SH3 domain
chrX_+_68678712 0.446 ENSMUST00000114654.1
ENSMUST00000114655.1
ENSMUST00000114657.2
ENSMUST00000114653.1
Fmr1



fragile X mental retardation syndrome 1



chr7_+_141461075 0.434 ENSMUST00000053670.5
Efcab4a
EF-hand calcium binding domain 4A
chr12_-_70111920 0.417 ENSMUST00000169074.1
ENSMUST00000021468.7
Nin

ninein

chr7_+_4690760 0.387 ENSMUST00000048248.7
Brsk1
BR serine/threonine kinase 1
chr15_+_78428564 0.378 ENSMUST00000166142.2
ENSMUST00000162517.1
ENSMUST00000089414.4
Kctd17


potassium channel tetramerisation domain containing 17


chr5_-_122264378 0.363 ENSMUST00000111738.3
Tctn1
tectonic family member 1
chr7_-_122067263 0.356 ENSMUST00000033159.3
Ears2
glutamyl-tRNA synthetase 2 (mitochondrial)(putative)
chr13_+_12565868 0.353 ENSMUST00000071973.6
Ero1lb
ERO1-like beta (S. cerevisiae)
chr9_-_107710475 0.350 ENSMUST00000080560.3
Sema3f
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chrX_-_166585679 0.348 ENSMUST00000000412.2
Egfl6
EGF-like-domain, multiple 6
chr10_+_121365078 0.328 ENSMUST00000040344.6
Gns
glucosamine (N-acetyl)-6-sulfatase
chr10_-_82622926 0.327 ENSMUST00000176200.1
ENSMUST00000183416.1
1190007I07Rik

RIKEN cDNA 1190007I07 gene

chr17_+_3114957 0.317 ENSMUST00000076734.6
Scaf8
SR-related CTD-associated factor 8
chr14_-_31830402 0.289 ENSMUST00000014640.7
Ankrd28
ankyrin repeat domain 28
chr2_+_25242929 0.288 ENSMUST00000114355.1
ENSMUST00000060818.1
Rnf208

ring finger protein 208

chr7_+_100372224 0.282 ENSMUST00000051777.8
ENSMUST00000098259.4
C2cd3

C2 calcium-dependent domain containing 3

chr7_+_122067164 0.278 ENSMUST00000033158.4
Ubfd1
ubiquitin family domain containing 1
chr2_+_154436437 0.276 ENSMUST00000109725.1
ENSMUST00000099178.3
ENSMUST00000045270.8
ENSMUST00000109724.1
Cbfa2t2



core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human)



chr2_+_178141920 0.275 ENSMUST00000103066.3
Phactr3
phosphatase and actin regulator 3
chr2_-_165884636 0.275 ENSMUST00000177633.1
ENSMUST00000018050.7
ENSMUST00000088113.4
Zmynd8


zinc finger, MYND-type containing 8


chr2_+_28205648 0.268 ENSMUST00000102879.3
ENSMUST00000028177.4
Olfm1

olfactomedin 1

chr5_-_137741102 0.260 ENSMUST00000149512.1
Nyap1
neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1
chr8_+_124897877 0.256 ENSMUST00000034467.5
Sprtn
SprT-like N-terminal domain
chr7_-_31055594 0.253 ENSMUST00000039909.6
Fxyd1
FXYD domain-containing ion transport regulator 1
chr7_-_28766469 0.246 ENSMUST00000085851.5
ENSMUST00000032815.4
Nfkbib

nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta

chr7_-_29156160 0.237 ENSMUST00000144795.1
ENSMUST00000134176.1
ENSMUST00000164589.1
ENSMUST00000136256.1
Fam98c



family with sequence similarity 98, member C



chrX_-_103981242 0.229 ENSMUST00000121153.1
ENSMUST00000070705.4
Rlim

ring finger protein, LIM domain interacting

chr15_-_99370427 0.225 ENSMUST00000081224.7
ENSMUST00000120633.1
ENSMUST00000088233.6
Fmnl3


formin-like 3


chr9_+_106477269 0.223 ENSMUST00000047721.8
Rrp9
RRP9, small subunit (SSU) processome component, homolog (yeast)
chr14_+_21499770 0.211 ENSMUST00000182855.1
ENSMUST00000069648.7
ENSMUST00000182405.1
Kat6b


K(lysine) acetyltransferase 6B


chr5_-_137741601 0.203 ENSMUST00000119498.1
ENSMUST00000061789.7
Nyap1

neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1

chr17_+_4994904 0.203 ENSMUST00000092723.4
ENSMUST00000115797.2
Arid1b

AT rich interactive domain 1B (SWI-like)

chr12_-_86884808 0.193 ENSMUST00000038422.6
Irf2bpl
interferon regulatory factor 2 binding protein-like
chr8_+_71469186 0.180 ENSMUST00000124745.1
ENSMUST00000138892.1
ENSMUST00000147642.1
Dda1


DET1 and DDB1 associated 1


chr15_-_50890396 0.178 ENSMUST00000185183.1
Trps1
trichorhinophalangeal syndrome I (human)
chr7_+_78578830 0.172 ENSMUST00000064591.4
Gm9885
predicted gene 9885
chr19_+_4154606 0.161 ENSMUST00000061086.8
Ptprcap
protein tyrosine phosphatase, receptor type, C polypeptide-associated protein
chr2_-_152831112 0.161 ENSMUST00000128172.1
Bcl2l1
BCL2-like 1
chr7_+_4690604 0.157 ENSMUST00000120836.1
Brsk1
BR serine/threonine kinase 1
chr15_-_100422991 0.156 ENSMUST00000138843.1
ENSMUST00000023774.5
Slc11a2

solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2

chr6_-_29609811 0.145 ENSMUST00000012679.8
Tnpo3
transportin 3
chr7_-_45814302 0.141 ENSMUST00000107729.1
ENSMUST00000056820.6
Cyth2

cytohesin 2

chr7_-_45814277 0.139 ENSMUST00000107728.1
Cyth2
cytohesin 2
chr6_-_124415037 0.113 ENSMUST00000035861.5
ENSMUST00000112532.1
ENSMUST00000080557.5
Pex5


peroxisomal biogenesis factor 5


chr7_-_100371889 0.096 ENSMUST00000032963.8
Ppme1
protein phosphatase methylesterase 1
chr7_-_19715395 0.095 ENSMUST00000032555.9
ENSMUST00000093552.5
Tomm40

translocase of outer mitochondrial membrane 40 homolog (yeast)

chr7_+_6286573 0.094 ENSMUST00000086327.5
Zfp667
zinc finger protein 667
chr10_-_82623190 0.090 ENSMUST00000183363.1
ENSMUST00000079648.5
ENSMUST00000185168.1
1190007I07Rik


RIKEN cDNA 1190007I07 gene


chr7_+_6286589 0.083 ENSMUST00000170776.1
Zfp667
zinc finger protein 667
chr5_-_122900267 0.078 ENSMUST00000031435.7
Kdm2b
lysine (K)-specific demethylase 2B
chr7_-_101933815 0.066 ENSMUST00000106963.1
ENSMUST00000106966.1
Lrrc51

leucine rich repeat containing 51

chr1_+_87620334 0.066 ENSMUST00000042275.8
ENSMUST00000168783.1
Inpp5d

inositol polyphosphate-5-phosphatase D

chr12_-_12940600 0.060 ENSMUST00000130990.1
Mycn
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr19_+_5637475 0.046 ENSMUST00000025867.5
Rela
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
chr17_-_46680870 0.044 ENSMUST00000165007.1
ENSMUST00000071841.5
Klhdc3

kelch domain containing 3

chr19_+_4756557 0.043 ENSMUST00000036744.7
Rbm4b
RNA binding motif protein 4B
chr16_-_92466081 0.039 ENSMUST00000060005.8
Rcan1
regulator of calcineurin 1
chr4_-_130174691 0.026 ENSMUST00000132545.2
ENSMUST00000175992.1
ENSMUST00000105999.2
Tinagl1


tubulointerstitial nephritis antigen-like 1


chr4_+_129960760 0.025 ENSMUST00000139884.1
1700003M07Rik
RIKEN cDNA 1700003M07 gene
chr6_-_29609607 0.015 ENSMUST00000115251.1
Tnpo3
transportin 3
chr3_-_108536466 0.014 ENSMUST00000048012.6
ENSMUST00000106626.2
ENSMUST00000106625.3
5330417C22Rik


RIKEN cDNA 5330417C22 gene


chr7_-_45016224 0.012 ENSMUST00000085383.2
Scaf1
SR-related CTD-associated factor 1
chr2_-_152831665 0.011 ENSMUST00000156688.1
ENSMUST00000007803.5
Bcl2l1

BCL2-like 1

chr8_-_69902712 0.004 ENSMUST00000180068.1
Yjefn3
YjeF N-terminal domain containing 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.6 1.8 GO:0099547 regulation of translation at synapse, modulating synaptic transmission(GO:0099547) regulation of translation at postsynapse, modulating synaptic transmission(GO:0099578) positive regulation of intracellular transport of viral material(GO:1901254)
0.4 1.1 GO:0006553 lysine metabolic process(GO:0006553)
0.3 1.5 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.3 0.6 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.3 0.8 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.2 0.7 GO:2000569 T-helper 2 cell activation(GO:0035712) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570)
0.2 1.4 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.2 0.5 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.2 1.4 GO:0005513 detection of calcium ion(GO:0005513)
0.2 1.2 GO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300)
0.2 0.7 GO:0043974 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.1 0.6 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 0.6 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.1 0.4 GO:0030070 insulin processing(GO:0030070)
0.1 2.0 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.1 1.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 1.1 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 1.4 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.9 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 1.6 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.8 GO:0097264 self proteolysis(GO:0097264)
0.1 0.5 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.8 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.6 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 3.5 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 0.2 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.1 0.4 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 0.3 GO:0097491 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.1 0.3 GO:0061511 centriole elongation(GO:0061511)
0.1 0.3 GO:1903756 regulation of postsynaptic density protein 95 clustering(GO:1902897) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 6.0 GO:0007631 feeding behavior(GO:0007631)
0.1 1.0 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 0.4 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.1 0.4 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.1 0.3 GO:1903795 regulation of inorganic anion transmembrane transport(GO:1903795)
0.0 0.2 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.0 0.2 GO:0046898 response to cycloheximide(GO:0046898)
0.0 0.9 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.2 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 1.0 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 0.8 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.0 0.1 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.0 0.2 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.0 0.5 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.5 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.3 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.3 GO:2001223 neuronal signal transduction(GO:0023041) negative regulation of neuron migration(GO:2001223)
0.0 0.9 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.0 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.1 GO:0045658 negative regulation of interleukin-6 biosynthetic process(GO:0045409) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.0 0.2 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.5 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.3 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.8 GO:0050919 negative chemotaxis(GO:0050919)
0.0 1.5 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.5 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 0.3 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.1 GO:1990761 growth cone lamellipodium(GO:1990761)
0.6 1.8 GO:1990812 growth cone filopodium(GO:1990812)
0.5 1.5 GO:0043512 inhibin A complex(GO:0043512)
0.3 1.4 GO:0030314 junctional membrane complex(GO:0030314)
0.1 0.6 GO:0001940 male pronucleus(GO:0001940)
0.1 0.5 GO:0033010 paranodal junction(GO:0033010)
0.1 3.5 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 0.4 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.9 GO:0000145 exocyst(GO:0000145)
0.0 5.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.3 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 1.6 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.6 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.4 GO:0008180 COP9 signalosome(GO:0008180)
0.0 2.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.5 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.7 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 2.0 GO:0000922 spindle pole(GO:0000922)
0.0 0.7 GO:0016235 aggresome(GO:0016235)
0.0 0.3 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.2 GO:0016514 SWI/SNF complex(GO:0016514)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.3 1.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.3 1.8 GO:0033592 RNA strand annealing activity(GO:0033592)
0.3 1.5 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.5 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739) tubulin deacetylase activity(GO:0042903)
0.1 0.9 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.6 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.7 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 3.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 1.0 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 1.5 GO:0045499 chemorepellent activity(GO:0045499)
0.1 1.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 1.1 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.2 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 0.6 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 2.2 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.7 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.4 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.3 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.2 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.8 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 1.2 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 0.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.9 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 1.5 PID_ALK1_PATHWAY ALK1 signaling events
0.0 0.8 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.7 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.7 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.1 3.5 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.2 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.1 1.4 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.1 1.8 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.6 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.6 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.3 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.4 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.5 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.5 REACTOME_IL1_SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.3 REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.2 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes