Motif ID: Sox15

Z-value: 0.417


Transcription factors associated with Sox15:

Gene SymbolEntrez IDGene Name
Sox15 ENSMUSG00000041287.5 Sox15



Activity profile for motif Sox15.

activity profile for motif Sox15


Sorted Z-values histogram for motif Sox15

Sorted Z-values for motif Sox15



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox15

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_23248264 3.262 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr7_-_49636847 1.915 ENSMUST00000032717.6
Dbx1
developing brain homeobox 1
chr1_-_138842429 1.897 ENSMUST00000112026.2
ENSMUST00000019374.7
Lhx9

LIM homeobox protein 9

chrX_+_112604274 1.296 ENSMUST00000071814.6
Zfp711
zinc finger protein 711
chr2_-_65567465 1.243 ENSMUST00000066432.5
Scn3a
sodium channel, voltage-gated, type III, alpha
chr2_-_65567505 1.179 ENSMUST00000100069.2
Scn3a
sodium channel, voltage-gated, type III, alpha
chrX_+_109095359 1.107 ENSMUST00000033598.8
Sh3bgrl
SH3-binding domain glutamic acid-rich protein like
chrX_+_112600526 0.872 ENSMUST00000113409.1
Zfp711
zinc finger protein 711
chr7_+_82867327 0.869 ENSMUST00000082237.5
Mex3b
mex3 homolog B (C. elegans)
chr5_+_148265307 0.828 ENSMUST00000110514.1
Mtus2
microtubule associated tumor suppressor candidate 2
chr14_-_48662740 0.799 ENSMUST00000122009.1
Otx2
orthodenticle homolog 2 (Drosophila)
chr5_+_148265202 0.753 ENSMUST00000110515.2
Mtus2
microtubule associated tumor suppressor candidate 2
chr8_+_108714644 0.709 ENSMUST00000043896.8
Zfhx3
zinc finger homeobox 3
chr10_+_53596936 0.699 ENSMUST00000020004.6
Asf1a
ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chr8_+_45507768 0.694 ENSMUST00000067065.7
ENSMUST00000098788.3
ENSMUST00000067107.7
ENSMUST00000171337.2
ENSMUST00000138049.1
ENSMUST00000141039.1
Sorbs2





sorbin and SH3 domain containing 2





chr5_+_148265265 0.617 ENSMUST00000071878.5
Mtus2
microtubule associated tumor suppressor candidate 2
chr3_-_33082004 0.616 ENSMUST00000108225.3
Pex5l
peroxisomal biogenesis factor 5-like
chr1_+_55406163 0.607 ENSMUST00000042986.8
Plcl1
phospholipase C-like 1
chr3_+_58415689 0.605 ENSMUST00000099090.2
Tsc22d2
TSC22 domain family, member 2
chr18_+_33464163 0.594 ENSMUST00000097634.3
Gm10549
predicted gene 10549
chr6_+_86404219 0.588 ENSMUST00000095754.3
ENSMUST00000095753.2
Tia1

cytotoxic granule-associated RNA binding protein 1

chr10_-_30655859 0.587 ENSMUST00000092610.4
Ncoa7
nuclear receptor coactivator 7
chr4_-_34882919 0.555 ENSMUST00000098163.2
ENSMUST00000047950.5
Zfp292

zinc finger protein 292

chr9_+_54863742 0.549 ENSMUST00000034843.7
Ireb2
iron responsive element binding protein 2
chr10_-_37138863 0.535 ENSMUST00000092584.5
Marcks
myristoylated alanine rich protein kinase C substrate
chr6_+_65042575 0.534 ENSMUST00000031984.6
Smarcad1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr6_+_17065129 0.530 ENSMUST00000115467.4
ENSMUST00000154266.2
ENSMUST00000076654.7
Tes


testis derived transcript


chr11_+_88068242 0.526 ENSMUST00000018521.4
Vezf1
vascular endothelial zinc finger 1
chr18_+_11633276 0.512 ENSMUST00000115861.2
Rbbp8
retinoblastoma binding protein 8
chr19_+_55741810 0.510 ENSMUST00000111657.3
ENSMUST00000061496.9
ENSMUST00000041717.7
ENSMUST00000111662.4
Tcf7l2



transcription factor 7 like 2, T cell specific, HMG box



chr9_-_103480328 0.488 ENSMUST00000124310.2
Bfsp2
beaded filament structural protein 2, phakinin
chr3_-_8964037 0.483 ENSMUST00000091354.5
ENSMUST00000094381.4
Tpd52

tumor protein D52

chr12_+_40446050 0.467 ENSMUST00000037488.6
Dock4
dedicator of cytokinesis 4
chr6_+_86404336 0.450 ENSMUST00000113713.2
ENSMUST00000113708.1
Tia1

cytotoxic granule-associated RNA binding protein 1

chr15_-_79658889 0.406 ENSMUST00000109648.2
ENSMUST00000046816.6
Fam227a

family with sequence similarity 227, member A

chr6_+_86404257 0.402 ENSMUST00000095752.2
ENSMUST00000130967.1
Tia1

cytotoxic granule-associated RNA binding protein 1

chr17_+_52602700 0.391 ENSMUST00000039366.10
Kcnh8
potassium voltage-gated channel, subfamily H (eag-related), member 8
chr17_+_53479212 0.379 ENSMUST00000017975.5
Rab5a
RAB5A, member RAS oncogene family
chr4_-_129742275 0.371 ENSMUST00000066257.5
Khdrbs1
KH domain containing, RNA binding, signal transduction associated 1
chr12_+_37241633 0.368 ENSMUST00000049874.7
Agmo
alkylglycerol monooxygenase
chr10_+_17796256 0.357 ENSMUST00000037964.6
Txlnb
taxilin beta
chr6_+_125552948 0.343 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Vwf


Von Willebrand factor homolog


chr16_-_18621366 0.333 ENSMUST00000051160.2
Gp1bb
glycoprotein Ib, beta polypeptide
chr10_+_57486354 0.333 ENSMUST00000079833.4
Hsf2
heat shock factor 2
chr10_-_116473418 0.332 ENSMUST00000087965.4
ENSMUST00000164271.1
Kcnmb4

potassium large conductance calcium-activated channel, subfamily M, beta member 4

chr6_+_86628174 0.324 ENSMUST00000043400.6
Asprv1
aspartic peptidase, retroviral-like 1
chr4_-_70534904 0.321 ENSMUST00000107359.2
Megf9
multiple EGF-like-domains 9
chr11_+_87760533 0.317 ENSMUST00000039627.5
ENSMUST00000100644.3
Bzrap1

benzodiazepine receptor associated protein 1

chr19_-_56822161 0.310 ENSMUST00000118592.1
A630007B06Rik
RIKEN cDNA A630007B06 gene
chr9_+_74976096 0.305 ENSMUST00000081746.5
Fam214a
family with sequence similarity 214, member A
chr2_-_60125651 0.304 ENSMUST00000112550.1
Baz2b
bromodomain adjacent to zinc finger domain, 2B
chrX_+_71556874 0.304 ENSMUST00000123100.1
Hmgb3
high mobility group box 3
chrX_+_73757069 0.299 ENSMUST00000002079.6
Plxnb3
plexin B3
chr1_+_19212054 0.294 ENSMUST00000064976.4
Tfap2b
transcription factor AP-2 beta
chr11_-_49712674 0.278 ENSMUST00000020624.6
ENSMUST00000145353.1
Cnot6

CCR4-NOT transcription complex, subunit 6

chr6_-_86733268 0.278 ENSMUST00000001185.7
Gmcl1
germ cell-less homolog 1 (Drosophila)
chr3_+_31902666 0.271 ENSMUST00000119970.1
ENSMUST00000178668.1
Kcnmb2

potassium large conductance calcium-activated channel, subfamily M, beta member 2

chr15_-_58214882 0.260 ENSMUST00000022986.6
Fbxo32
F-box protein 32
chr13_+_21722057 0.256 ENSMUST00000110476.3
Hist1h2bm
histone cluster 1, H2bm
chr12_-_40445754 0.244 ENSMUST00000069692.8
ENSMUST00000069637.7
Zfp277

zinc finger protein 277

chr10_+_116301374 0.237 ENSMUST00000092167.5
Ptprb
protein tyrosine phosphatase, receptor type, B
chr3_+_131110350 0.231 ENSMUST00000066849.6
ENSMUST00000106341.2
ENSMUST00000029611.7
Lef1


lymphoid enhancer binding factor 1


chr1_-_33814516 0.221 ENSMUST00000044455.5
ENSMUST00000115167.1
Zfp451

zinc finger protein 451

chr19_+_40831248 0.220 ENSMUST00000025983.6
ENSMUST00000120057.1
Ccnj

cyclin J

chr17_-_70851189 0.211 ENSMUST00000059775.8
Tgif1
TGFB-induced factor homeobox 1
chr15_-_79658749 0.210 ENSMUST00000109646.2
Fam227a
family with sequence similarity 227, member A
chrX_-_57392962 0.209 ENSMUST00000114730.1
Rbmx
RNA binding motif protein, X chromosome
chr19_-_46962301 0.208 ENSMUST00000168536.1
Nt5c2
5'-nucleotidase, cytosolic II
chrX_-_57393020 0.196 ENSMUST00000143310.1
ENSMUST00000098470.2
ENSMUST00000114726.1
Rbmx


RNA binding motif protein, X chromosome


chr17_+_55445550 0.186 ENSMUST00000025000.3
St6gal2
beta galactoside alpha 2,6 sialyltransferase 2
chr11_+_94044331 0.186 ENSMUST00000024979.8
Spag9
sperm associated antigen 9
chr5_-_92083455 0.183 ENSMUST00000169094.1
ENSMUST00000167918.1
G3bp2

GTPase activating protein (SH3 domain) binding protein 2

chr6_+_17463749 0.179 ENSMUST00000115443.1
Met
met proto-oncogene
chr3_+_37639985 0.178 ENSMUST00000108107.1
Spry1
sprouty homolog 1 (Drosophila)
chrX_-_167209149 0.178 ENSMUST00000112176.1
Tmsb4x
thymosin, beta 4, X chromosome
chr5_+_33983437 0.178 ENSMUST00000114384.1
ENSMUST00000094869.5
ENSMUST00000114383.1
Gm1673


predicted gene 1673


chr6_+_17463826 0.176 ENSMUST00000140070.1
Met
met proto-oncogene
chr11_+_94044194 0.172 ENSMUST00000092777.4
ENSMUST00000075695.6
Spag9

sperm associated antigen 9

chr11_+_94044241 0.172 ENSMUST00000103168.3
Spag9
sperm associated antigen 9
chr2_+_29346803 0.170 ENSMUST00000028139.4
ENSMUST00000113830.4
Med27

mediator complex subunit 27

chr5_+_33983534 0.164 ENSMUST00000114382.1
Gm1673
predicted gene 1673
chr7_+_82174796 0.159 ENSMUST00000032874.7
Sh3gl3
SH3-domain GRB2-like 3
chr5_+_19907502 0.155 ENSMUST00000101558.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr9_-_35267746 0.155 ENSMUST00000125087.1
ENSMUST00000121564.1
ENSMUST00000063782.5
ENSMUST00000059057.7
Fam118b



family with sequence similarity 118, member B



chr10_+_43579161 0.152 ENSMUST00000058714.8
Cd24a
CD24a antigen
chr4_+_128688726 0.152 ENSMUST00000106080.1
Phc2
polyhomeotic-like 2 (Drosophila)
chr5_-_92083667 0.148 ENSMUST00000113127.3
G3bp2
GTPase activating protein (SH3 domain) binding protein 2
chr14_+_79515618 0.146 ENSMUST00000110835.1
Elf1
E74-like factor 1
chr2_-_170406501 0.146 ENSMUST00000154650.1
Bcas1
breast carcinoma amplified sequence 1
chr19_-_46039621 0.146 ENSMUST00000056931.7
Ldb1
LIM domain binding 1
chr18_-_34624562 0.139 ENSMUST00000003876.3
ENSMUST00000115766.1
ENSMUST00000097626.3
ENSMUST00000115765.1
Brd8



bromodomain containing 8



chr4_+_116557658 0.130 ENSMUST00000030460.8
Gpbp1l1
GC-rich promoter binding protein 1-like 1
chr2_+_18672384 0.124 ENSMUST00000171845.1
ENSMUST00000061158.4
Commd3

COMM domain containing 3

chr16_+_93607831 0.123 ENSMUST00000039659.8
Cbr1
carbonyl reductase 1
chr5_-_134946917 0.122 ENSMUST00000051401.2
Cldn4
claudin 4
chr6_+_17463927 0.115 ENSMUST00000115442.1
Met
met proto-oncogene
chr14_+_26638237 0.112 ENSMUST00000112318.3
Arf4
ADP-ribosylation factor 4
chr2_+_3114220 0.111 ENSMUST00000072955.5
Fam171a1
family with sequence similarity 171, member A1
chr15_+_99702278 0.110 ENSMUST00000023759.4
Smarcd1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr10_+_29143996 0.110 ENSMUST00000092629.2
Soga3
SOGA family member 3
chr7_-_127615208 0.101 ENSMUST00000122066.1
Zfp629
zinc finger protein 629
chr2_-_116067391 0.099 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr16_-_5013505 0.096 ENSMUST00000023191.10
ENSMUST00000090453.5
Rogdi

rogdi homolog (Drosophila)

chr7_+_82175156 0.084 ENSMUST00000180243.1
Sh3gl3
SH3-domain GRB2-like 3
chr11_-_77489666 0.083 ENSMUST00000037593.7
ENSMUST00000092892.3
Ankrd13b

ankyrin repeat domain 13b

chr6_-_132314757 0.082 ENSMUST00000048686.8
Prpmp5
proline-rich protein MP5
chr5_+_124862674 0.081 ENSMUST00000111417.2
Zfp664
zinc finger protein 664
chr11_-_87074055 0.074 ENSMUST00000020804.7
Gdpd1
glycerophosphodiester phosphodiesterase domain containing 1
chr18_+_4921662 0.074 ENSMUST00000143254.1
Svil
supervillin
chr19_+_40831296 0.069 ENSMUST00000119316.1
Ccnj
cyclin J
chr12_+_111039334 0.068 ENSMUST00000084968.7
Rcor1
REST corepressor 1
chr19_-_5729618 0.054 ENSMUST00000116558.2
ENSMUST00000099955.3
ENSMUST00000161368.1
Fam89b


family with sequence similarity 89, member B


chr2_+_176236860 0.052 ENSMUST00000166464.1
2210418O10Rik
RIKEN cDNA 2210418O10 gene
chr5_-_123721007 0.049 ENSMUST00000031376.7
Zcchc8
zinc finger, CCHC domain containing 8
chr7_+_126760591 0.026 ENSMUST00000091328.2
Mapk3
mitogen-activated protein kinase 3
chr6_+_17491216 0.025 ENSMUST00000080469.5
Met
met proto-oncogene
chr6_-_148944750 0.023 ENSMUST00000111562.1
ENSMUST00000081956.5
Fam60a

family with sequence similarity 60, member A

chr1_+_135146782 0.023 ENSMUST00000027684.4
Arl8a
ADP-ribosylation factor-like 8A
chr10_+_88091070 0.022 ENSMUST00000048621.7
Pmch
pro-melanin-concentrating hormone
chr10_+_87859255 0.021 ENSMUST00000105300.2
Igf1
insulin-like growth factor 1
chr11_+_61653259 0.017 ENSMUST00000004959.2
Grap
GRB2-related adaptor protein
chr10_+_87859062 0.015 ENSMUST00000095360.4
Igf1
insulin-like growth factor 1
chr9_+_35267857 0.010 ENSMUST00000034543.4
Rpusd4
RNA pseudouridylate synthase domain containing 4
chr10_-_95324072 0.009 ENSMUST00000053594.5
Cradd
CASP2 and RIPK1 domain containing adaptor with death domain
chr16_+_20097554 0.009 ENSMUST00000023509.3
Klhl24
kelch-like 24
chr12_-_83597140 0.007 ENSMUST00000048319.4
Zfyve1
zinc finger, FYVE domain containing 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.5 2.4 GO:0046684 response to pyrethroid(GO:0046684)
0.4 1.9 GO:0035262 gonad morphogenesis(GO:0035262)
0.2 0.7 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.2 0.8 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.2 0.5 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.1 1.4 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.1 0.9 GO:0072697 protein localization to cell cortex(GO:0072697)
0.1 0.6 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.1 0.5 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 1.9 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 0.5 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.1 0.3 GO:0097274 urea homeostasis(GO:0097274)
0.1 0.6 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1 0.3 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.2 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.1 0.6 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.2 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
0.1 0.5 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.1 0.4 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.5 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 0.3 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.1 0.3 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.1 0.5 GO:0000729 DNA double-strand break processing(GO:0000729)
0.1 0.3 GO:2000325 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.1 0.4 GO:0051036 regulation of endosome size(GO:0051036) receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 0.2 GO:0002842 positive regulation of T cell mediated immune response to tumor cell(GO:0002842) positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.6 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.2 GO:0030576 Cajal body organization(GO:0030576)
0.0 0.1 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.0 0.2 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.1 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.5 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.4 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.0 0.4 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.7 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.5 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.2 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.1 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0 0.1 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.2 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.7 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.3 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.0 GO:0042320 negative regulation of synaptic transmission, dopaminergic(GO:0032227) regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.0 0.2 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.2 GO:0038092 nodal signaling pathway(GO:0038092)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0042585 germinal vesicle(GO:0042585)
0.2 2.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.2 1.4 GO:0097165 nuclear stress granule(GO:0097165)
0.2 0.6 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 0.4 GO:0098842 postsynaptic early endosome(GO:0098842)
0.1 0.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.4 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.7 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 2.2 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.3 GO:0005604 basement membrane(GO:0005604)
0.0 0.5 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.1 GO:0000812 Swr1 complex(GO:0000812)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0030350 iron-responsive element binding(GO:0030350)
0.1 0.5 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.1 0.6 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 2.4 GO:0031402 sodium ion binding(GO:0031402)
0.1 0.7 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)
0.1 0.4 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.4 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 0.6 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.6 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.3 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 1.4 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.2 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.6 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.5 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.3 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.8 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.1 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.5 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.3 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.3 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.3 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 2.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID_BARD1_PATHWAY BARD1 signaling events
0.0 0.9 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.9 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.7 PID_AP1_PATHWAY AP-1 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.1 0.5 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.6 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.3 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.8 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.4 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling