Motif ID: Mafb

Z-value: 0.664


Transcription factors associated with Mafb:

Gene SymbolEntrez IDGene Name
Mafb ENSMUSG00000074622.3 Mafb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mafbmm10_v2_chr2_-_160367057_1603670730.704.6e-07Click!


Activity profile for motif Mafb.

activity profile for motif Mafb


Sorted Z-values histogram for motif Mafb

Sorted Z-values for motif Mafb



Network of associatons between targets according to the STRING database.



First level regulatory network of Mafb

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_120202104 3.694 ENSMUST00000033198.5
Crym
crystallin, mu
chr18_+_65873478 2.613 ENSMUST00000025395.8
ENSMUST00000173530.1
Grp

gastrin releasing peptide

chr14_+_80000292 2.034 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr11_+_75531690 2.018 ENSMUST00000149727.1
ENSMUST00000042561.7
ENSMUST00000108433.1
ENSMUST00000143035.1
Slc43a2



solute carrier family 43, member 2



chr11_-_116307168 2.015 ENSMUST00000124281.1
Exoc7
exocyst complex component 7
chr7_+_130936172 1.939 ENSMUST00000006367.7
Htra1
HtrA serine peptidase 1
chr19_+_26753588 1.932 ENSMUST00000177116.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr19_-_5510467 1.872 ENSMUST00000070172.4
Snx32
sorting nexin 32
chr17_-_6477102 1.845 ENSMUST00000167717.2
Tmem181b-ps
transmembrane protein 181B, pseudogene
chr17_+_6270475 1.809 ENSMUST00000088940.4
Tmem181a
transmembrane protein 181A
chr17_+_3532554 1.787 ENSMUST00000168560.1
Cldn20
claudin 20
chr4_-_136886187 1.771 ENSMUST00000046384.8
C1qb
complement component 1, q subcomponent, beta polypeptide
chr2_+_170731807 1.765 ENSMUST00000029075.4
Dok5
docking protein 5
chr9_-_18473559 1.724 ENSMUST00000034647.4
Zfp558
zinc finger protein 558
chr7_-_141010759 1.641 ENSMUST00000026565.6
Ifitm3
interferon induced transmembrane protein 3
chr10_-_42276688 1.636 ENSMUST00000175881.1
ENSMUST00000056974.3
Foxo3

forkhead box O3

chr10_+_40349265 1.588 ENSMUST00000044672.4
ENSMUST00000095743.2
Cdk19

cyclin-dependent kinase 19

chr3_+_94398517 1.539 ENSMUST00000050975.3
Lingo4
leucine rich repeat and Ig domain containing 4
chr2_-_31116289 1.528 ENSMUST00000149196.1
Fnbp1
formin binding protein 1
chr7_+_4137032 1.509 ENSMUST00000128756.1
ENSMUST00000132086.1
ENSMUST00000037472.6
ENSMUST00000117274.1
ENSMUST00000121270.1
Leng8




leukocyte receptor cluster (LRC) member 8




chr6_+_72097561 1.500 ENSMUST00000069994.4
ENSMUST00000114112.1
St3gal5

ST3 beta-galactoside alpha-2,3-sialyltransferase 5

chr8_+_25532125 1.491 ENSMUST00000167764.1
Fgfr1
fibroblast growth factor receptor 1
chr6_+_120773633 1.489 ENSMUST00000112682.2
Slc25a18
solute carrier family 25 (mitochondrial carrier), member 18
chr17_+_22689771 1.469 ENSMUST00000055305.8
Gm9805
predicted gene 9805
chr7_+_141029131 1.462 ENSMUST00000170892.1
Gm17387
predicted gene, 17387
chr2_-_127482499 1.391 ENSMUST00000088538.5
Kcnip3
Kv channel interacting protein 3, calsenilin
chr2_-_33131645 1.356 ENSMUST00000133135.1
Garnl3
GTPase activating RANGAP domain-like 3
chr7_-_46672537 1.339 ENSMUST00000049298.7
Tph1
tryptophan hydroxylase 1
chr15_-_33687840 1.331 ENSMUST00000042021.3
Tspyl5
testis-specific protein, Y-encoded-like 5
chr4_-_41124292 1.316 ENSMUST00000030138.8
Nol6
nucleolar protein family 6 (RNA-associated)
chr5_+_140505550 1.297 ENSMUST00000043050.8
ENSMUST00000124142.1
Chst12

carbohydrate sulfotransferase 12

chr1_+_127306706 1.294 ENSMUST00000171405.1
Mgat5
mannoside acetylglucosaminyltransferase 5
chr10_-_62379852 1.287 ENSMUST00000143236.1
ENSMUST00000133429.1
ENSMUST00000132926.1
ENSMUST00000116238.2
Hk1



hexokinase 1



chr2_-_168741898 1.280 ENSMUST00000109176.1
ENSMUST00000178504.1
Atp9a

ATPase, class II, type 9A

chr10_+_127705170 1.268 ENSMUST00000079590.5
Myo1a
myosin IA
chr9_+_45838572 1.237 ENSMUST00000078111.4
ENSMUST00000034591.4
Bace1

beta-site APP cleaving enzyme 1

chrX_-_95196450 1.236 ENSMUST00000181987.1
Arhgef9
CDC42 guanine nucleotide exchange factor (GEF) 9
chr2_+_3713478 1.197 ENSMUST00000115053.2
Fam107b
family with sequence similarity 107, member B
chr7_+_44590886 1.184 ENSMUST00000107906.3
Kcnc3
potassium voltage gated channel, Shaw-related subfamily, member 3
chr3_+_65109343 1.180 ENSMUST00000159525.1
ENSMUST00000049230.8
Kcnab1

potassium voltage-gated channel, shaker-related subfamily, beta member 1

chr10_+_62920648 1.175 ENSMUST00000144459.1
Slc25a16
solute carrier family 25 (mitochondrial carrier, Graves disease autoantigen), member 16
chr8_-_85119637 1.167 ENSMUST00000098550.3
Zfp791
zinc finger protein 791
chr4_+_102421518 1.154 ENSMUST00000106904.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr10_-_42276744 1.124 ENSMUST00000105502.1
ENSMUST00000105501.1
Foxo3

forkhead box O3

chr7_+_112742025 1.116 ENSMUST00000164363.1
Tead1
TEA domain family member 1
chr6_+_124997062 1.097 ENSMUST00000159391.1
Pianp
PILR alpha associated neural protein
chr15_+_82252397 1.071 ENSMUST00000136948.1
1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr9_+_109931458 1.029 ENSMUST00000072772.5
ENSMUST00000035055.8
Map4

microtubule-associated protein 4

chr18_+_37477768 1.024 ENSMUST00000051442.5
Pcdhb16
protocadherin beta 16
chr9_+_45403138 0.994 ENSMUST00000041005.5
Fxyd2
FXYD domain-containing ion transport regulator 2
chr13_-_74376566 0.972 ENSMUST00000091481.2
Zfp72
zinc finger protein 72
chr11_+_84880308 0.970 ENSMUST00000020837.6
Myo19
myosin XIX
chr8_-_36249292 0.939 ENSMUST00000065297.5
Lonrf1
LON peptidase N-terminal domain and ring finger 1
chr11_+_42419729 0.935 ENSMUST00000007797.4
Gabrb2
gamma-aminobutyric acid (GABA) A receptor, subunit beta 2
chr4_+_42035113 0.935 ENSMUST00000098127.1
Gm10597
predicted gene 10597
chr11_-_48871408 0.914 ENSMUST00000097271.2
Irgm1
immunity-related GTPase family M member 1
chr4_+_139352587 0.912 ENSMUST00000147999.1
ENSMUST00000042096.7
ENSMUST00000179784.1
ENSMUST00000082262.7
Ubr4
Emc1


ubiquitin protein ligase E3 component n-recognin 4
ER membrane protein complex subunit 1


chr8_-_111259192 0.906 ENSMUST00000169020.1
ENSMUST00000003404.8
Glg1

golgi apparatus protein 1

chr5_+_141856692 0.899 ENSMUST00000074546.6
Sdk1
sidekick homolog 1 (chicken)
chr11_-_116086929 0.889 ENSMUST00000074628.6
ENSMUST00000106444.3
Wbp2

WW domain binding protein 2

chr8_+_70172383 0.886 ENSMUST00000002413.8
ENSMUST00000182980.1
ENSMUST00000182365.1
Tmem161a


transmembrane protein 161A


chr9_+_109931863 0.880 ENSMUST00000165876.1
Map4
microtubule-associated protein 4
chr2_-_30124454 0.836 ENSMUST00000044751.8
Zer1
zyg-11 related, cell cycle regulator
chr9_-_121995962 0.834 ENSMUST00000084743.5
Pomgnt2
protein O-linked mannose beta 1,4-N-acetylglucosaminyltransferase 2
chr8_-_83694004 0.825 ENSMUST00000144258.1
Pkn1
protein kinase N1
chr11_+_116966731 0.821 ENSMUST00000136584.1
Mgat5b
mannoside acetylglucosaminyltransferase 5, isoenzyme B
chr11_-_69837781 0.821 ENSMUST00000108634.2
Nlgn2
neuroligin 2
chr5_-_92042999 0.808 ENSMUST00000069937.4
ENSMUST00000086978.5
Cdkl2

cyclin-dependent kinase-like 2 (CDC2-related kinase)

chr11_+_46055973 0.806 ENSMUST00000011400.7
Adam19
a disintegrin and metallopeptidase domain 19 (meltrin beta)
chr11_+_120713919 0.805 ENSMUST00000026139.7
ENSMUST00000151852.1
Lrrc45

leucine rich repeat containing 45

chr17_-_71460395 0.801 ENSMUST00000180522.1
Gm4707
predicted gene 4707
chr18_+_37447641 0.793 ENSMUST00000052387.3
Pcdhb14
protocadherin beta 14
chr2_-_130397525 0.788 ENSMUST00000028897.7
Cpxm1
carboxypeptidase X 1 (M14 family)
chr11_-_120630516 0.787 ENSMUST00000106181.1
Mafg
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr1_-_136260873 0.769 ENSMUST00000086395.5
Gpr25
G protein-coupled receptor 25
chr5_+_103754560 0.760 ENSMUST00000153165.1
ENSMUST00000031256.5
Aff1

AF4/FMR2 family, member 1

chr9_-_77347816 0.757 ENSMUST00000184138.1
ENSMUST00000184006.1
ENSMUST00000185144.1
ENSMUST00000034910.9
Mlip



muscular LMNA-interacting protein



chr2_-_30124529 0.751 ENSMUST00000113677.1
Zer1
zyg-11 related, cell cycle regulator
chr11_-_69805617 0.748 ENSMUST00000051025.4
Tmem102
transmembrane protein 102
chr13_-_54611274 0.745 ENSMUST00000049575.7
Cltb
clathrin, light polypeptide (Lcb)
chr6_+_29279587 0.741 ENSMUST00000167131.1
Fam71f2
family with sequence similarity 71, member F2
chr1_-_40790642 0.720 ENSMUST00000039672.5
Mfsd9
major facilitator superfamily domain containing 9
chr7_+_12965831 0.714 ENSMUST00000038701.7
Zfp324
zinc finger protein 324
chr10_-_78295394 0.710 ENSMUST00000105387.1
Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr8_-_69791170 0.695 ENSMUST00000131784.1
Zfp866
zinc finger protein 866
chr2_-_79428891 0.693 ENSMUST00000143974.1
Cerkl
ceramide kinase-like
chr2_+_3713449 0.683 ENSMUST00000027965.4
Fam107b
family with sequence similarity 107, member B
chr6_+_39573858 0.675 ENSMUST00000140364.1
Adck2
aarF domain containing kinase 2
chr9_-_122903102 0.674 ENSMUST00000180877.1
ENSMUST00000180486.1
A530083I20Rik

RIKEN cDNA A530083I20 gene

chr2_+_181319806 0.667 ENSMUST00000153112.1
Rtel1
regulator of telomere elongation helicase 1
chr2_-_166713758 0.664 ENSMUST00000036719.5
Prex1
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
chr6_+_34029421 0.656 ENSMUST00000070189.3
ENSMUST00000101564.2
Lrguk

leucine-rich repeats and guanylate kinase domain containing

chr12_+_35047180 0.651 ENSMUST00000048519.9
ENSMUST00000163677.1
Snx13

sorting nexin 13

chr10_+_34297421 0.650 ENSMUST00000047935.6
Tspyl4
TSPY-like 4
chr2_-_66256576 0.641 ENSMUST00000125446.2
ENSMUST00000102718.3
Ttc21b

tetratricopeptide repeat domain 21B

chr7_-_30743681 0.626 ENSMUST00000182634.1
Gapdhs
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr18_+_65430945 0.622 ENSMUST00000049248.5
Malt1
mucosa associated lymphoid tissue lymphoma translocation gene 1
chr4_-_45012287 0.618 ENSMUST00000055028.8
ENSMUST00000180217.1
ENSMUST00000107817.2
Zbtb5


zinc finger and BTB domain containing 5


chr7_+_140941550 0.618 ENSMUST00000079403.4
Athl1
ATH1, acid trehalase-like 1 (yeast)
chr3_-_131303144 0.610 ENSMUST00000106337.2
Cyp2u1
cytochrome P450, family 2, subfamily u, polypeptide 1
chr2_+_62046580 0.609 ENSMUST00000054484.8
Slc4a10
solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
chr11_-_121388186 0.608 ENSMUST00000106107.2
Rab40b
Rab40b, member RAS oncogene family
chr1_-_121327776 0.589 ENSMUST00000160688.1
Insig2
insulin induced gene 2
chr2_+_32621750 0.589 ENSMUST00000113278.2
Ak1
adenylate kinase 1
chr2_-_175131864 0.584 ENSMUST00000108929.2
Gm14399
predicted gene 14399
chr4_-_40722307 0.580 ENSMUST00000181475.1
Gm6297
predicted gene 6297
chr8_+_69808672 0.579 ENSMUST00000036074.8
ENSMUST00000123453.1
Gmip

Gem-interacting protein

chr10_-_128744014 0.572 ENSMUST00000026414.7
Dgka
diacylglycerol kinase, alpha
chr11_-_48871344 0.570 ENSMUST00000049519.3
Irgm1
immunity-related GTPase family M member 1
chr17_+_66111605 0.565 ENSMUST00000116556.2
Wash
WAS protein family homolog
chr9_-_101034857 0.553 ENSMUST00000142676.1
ENSMUST00000149322.1
Pccb

propionyl Coenzyme A carboxylase, beta polypeptide

chr11_-_120630126 0.553 ENSMUST00000106180.1
Mafg
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr1_-_121327734 0.552 ENSMUST00000160968.1
ENSMUST00000162582.1
Insig2

insulin induced gene 2

chr13_+_54503779 0.552 ENSMUST00000121401.1
ENSMUST00000118072.1
ENSMUST00000159721.1
Simc1


SUMO-interacting motifs containing 1


chr17_-_36042690 0.549 ENSMUST00000058801.8
ENSMUST00000080015.5
ENSMUST00000077960.6
H2-T22


histocompatibility 2, T region locus 22


chr3_+_90266507 0.539 ENSMUST00000098914.3
Dennd4b
DENN/MADD domain containing 4B
chr3_-_103737995 0.535 ENSMUST00000029440.8
Olfml3
olfactomedin-like 3
chr7_+_81523555 0.526 ENSMUST00000180385.1
ENSMUST00000180879.1
ENSMUST00000181164.1
ENSMUST00000181264.1
2900076A07Rik



RIKEN cDNA 2900076A07 gene



chr11_+_62574523 0.516 ENSMUST00000018651.7
Trpv2
transient receptor potential cation channel, subfamily V, member 2
chr2_+_30266721 0.512 ENSMUST00000113645.1
ENSMUST00000133877.1
ENSMUST00000139719.1
ENSMUST00000113643.1
ENSMUST00000150695.1
Phyhd1




phytanoyl-CoA dioxygenase domain containing 1




chr6_-_38837224 0.510 ENSMUST00000160962.1
Hipk2
homeodomain interacting protein kinase 2
chr4_+_136357423 0.510 ENSMUST00000182167.1
Gm17388
predicted gene, 17388
chr3_-_122619442 0.506 ENSMUST00000162947.1
Fnbp1l
formin binding protein 1-like
chr1_-_180245757 0.502 ENSMUST00000111104.1
Psen2
presenilin 2
chr12_+_84038363 0.496 ENSMUST00000021652.3
Acot4
acyl-CoA thioesterase 4
chr12_+_65225513 0.490 ENSMUST00000046331.4
Wdr20b
WD repeat domain 20b
chr13_-_85127514 0.490 ENSMUST00000179230.1
Gm4076
predicted gene 4076
chr18_-_64489042 0.481 ENSMUST00000025484.7
Fech
ferrochelatase
chr11_-_70229677 0.481 ENSMUST00000153449.1
ENSMUST00000000326.5
Bcl6b

B cell CLL/lymphoma 6, member B

chr14_-_66124482 0.480 ENSMUST00000070515.1
Ephx2
epoxide hydrolase 2, cytoplasmic
chr12_-_24493656 0.475 ENSMUST00000073088.2
Gm16372
predicted pseudogene 16372
chr9_-_73039697 0.464 ENSMUST00000184035.1
ENSMUST00000098566.4
Pigb

phosphatidylinositol glycan anchor biosynthesis, class B

chr7_-_97738222 0.457 ENSMUST00000084986.6
Aqp11
aquaporin 11
chr9_-_101034892 0.448 ENSMUST00000035116.5
Pccb
propionyl Coenzyme A carboxylase, beta polypeptide
chr5_-_135573036 0.448 ENSMUST00000004936.6
Ccl24
chemokine (C-C motif) ligand 24
chr12_-_108275409 0.444 ENSMUST00000136175.1
Ccdc85c
coiled-coil domain containing 85C
chr12_-_98259416 0.443 ENSMUST00000021390.7
Galc
galactosylceramidase
chr1_+_127868773 0.436 ENSMUST00000037649.5
Rab3gap1
RAB3 GTPase activating protein subunit 1
chr11_-_4849345 0.434 ENSMUST00000053079.6
ENSMUST00000109910.2
Nf2

neurofibromatosis 2

chr6_+_83795022 0.426 ENSMUST00000113851.1
Nagk
N-acetylglucosamine kinase
chr18_-_31820413 0.426 ENSMUST00000165131.2
Gm6665
predicted gene 6665
chr5_+_142463931 0.422 ENSMUST00000038699.8
Ap5z1
adaptor-related protein complex 5, zeta 1 subunit
chr2_+_181319714 0.420 ENSMUST00000098971.4
ENSMUST00000054622.8
ENSMUST00000108814.1
ENSMUST00000048608.9
ENSMUST00000108815.1
Rtel1




regulator of telomere elongation helicase 1




chr1_-_105659008 0.418 ENSMUST00000070699.8
Pign
phosphatidylinositol glycan anchor biosynthesis, class N
chr7_-_110862944 0.416 ENSMUST00000033050.3
Lyve1
lymphatic vessel endothelial hyaluronan receptor 1
chr6_+_83794974 0.414 ENSMUST00000037376.7
Nagk
N-acetylglucosamine kinase
chr3_-_116614587 0.407 ENSMUST00000041524.4
Trmt13
tRNA methyltransferase 13
chr12_+_76081645 0.406 ENSMUST00000154509.1
Syne2
spectrin repeat containing, nuclear envelope 2
chr9_-_77347787 0.405 ENSMUST00000184848.1
ENSMUST00000184415.1
Mlip

muscular LMNA-interacting protein

chr5_+_138229822 0.402 ENSMUST00000159798.1
ENSMUST00000159964.1
Nxpe5

neurexophilin and PC-esterase domain family, member 5

chr4_+_141793612 0.386 ENSMUST00000097805.4
ENSMUST00000030747.4
ENSMUST00000153094.1
Casp9


caspase 9


chr16_-_52452654 0.386 ENSMUST00000168071.1
Alcam
activated leukocyte cell adhesion molecule
chr15_+_76576386 0.384 ENSMUST00000160784.1
Adck5
aarF domain containing kinase 5
chr10_+_70204675 0.379 ENSMUST00000020090.1
2310015B20Rik
RIKEN cDNA 2310015B20 gene
chr5_+_140735526 0.377 ENSMUST00000120630.2
Amz1
archaelysin family metallopeptidase 1
chr16_-_43664145 0.376 ENSMUST00000096065.4
Tigit
T cell immunoreceptor with Ig and ITIM domains
chr17_+_15041641 0.369 ENSMUST00000097393.3
Ermard
ER membrane associated RNA degradation
chr7_-_140856254 0.368 ENSMUST00000026557.8
Bet1l
blocked early in transport 1 homolog (S. cerevisiae)-like
chr1_-_121328024 0.367 ENSMUST00000003818.7
Insig2
insulin induced gene 2
chr15_+_76576352 0.367 ENSMUST00000162503.1
Adck5
aarF domain containing kinase 5
chr6_-_137649211 0.366 ENSMUST00000134630.1
ENSMUST00000058210.6
ENSMUST00000111878.1
Eps8


epidermal growth factor receptor pathway substrate 8


chr5_+_122707546 0.366 ENSMUST00000081554.6
ENSMUST00000031429.7
ENSMUST00000139631.1
ENSMUST00000142664.1
P2rx4



purinergic receptor P2X, ligand-gated ion channel 4



chr2_-_32694120 0.362 ENSMUST00000028148.4
Fpgs
folylpolyglutamyl synthetase
chr14_+_118787894 0.358 ENSMUST00000047761.6
ENSMUST00000071546.7
Cldn10

claudin 10

chr13_+_23934434 0.355 ENSMUST00000072391.1
Hist1h2aa
histone cluster 1, H2aa
chr17_+_33920522 0.354 ENSMUST00000172489.1
Tapbp
TAP binding protein
chr9_+_44398176 0.348 ENSMUST00000165839.1
Slc37a4
solute carrier family 37 (glucose-6-phosphate transporter), member 4
chr8_+_69791163 0.336 ENSMUST00000034326.6
Atp13a1
ATPase type 13A1
chr6_-_34977999 0.334 ENSMUST00000044387.7
2010107G12Rik
RIKEN cDNA 2010107G12 gene
chr11_+_82101836 0.333 ENSMUST00000000194.3
Ccl12
chemokine (C-C motif) ligand 12
chr7_-_140882274 0.325 ENSMUST00000026559.7
Sirt3
sirtuin 3
chr11_+_75651504 0.322 ENSMUST00000069057.6
Myo1c
myosin IC
chr6_+_94500313 0.316 ENSMUST00000061118.8
Slc25a26
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 26
chr1_+_9547948 0.313 ENSMUST00000144177.1
Adhfe1
alcohol dehydrogenase, iron containing, 1
chr9_+_88581036 0.310 ENSMUST00000164661.2
Trim43a
tripartite motif-containing 43A
chr1_+_163929765 0.307 ENSMUST00000027876.4
ENSMUST00000170359.1
Scyl3

SCY1-like 3 (S. cerevisiae)

chr18_-_38338909 0.306 ENSMUST00000139885.1
Gnpda1
glucosamine-6-phosphate deaminase 1
chr8_+_4240105 0.297 ENSMUST00000110994.1
ENSMUST00000110995.1
Map2k7

mitogen-activated protein kinase kinase 7

chr11_+_20647149 0.295 ENSMUST00000109585.1
Sertad2
SERTA domain containing 2
chr9_+_65032413 0.290 ENSMUST00000034960.6
Dpp8
dipeptidylpeptidase 8
chr2_-_156857946 0.287 ENSMUST00000099141.2
4930518I15Rik
RIKEN cDNA 4930518I15 gene
chr5_+_121849021 0.284 ENSMUST00000056654.3
Fam109a
family with sequence similarity 109, member A
chr4_-_59138983 0.271 ENSMUST00000107547.1
AI481877
expressed sequence AI481877
chr13_-_23710714 0.268 ENSMUST00000091707.6
ENSMUST00000006787.7
ENSMUST00000091706.6
Hfe


hemochromatosis


chrX_+_104482774 0.268 ENSMUST00000087867.5
Uprt
uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
chr17_+_15010266 0.267 ENSMUST00000097395.3
Gm3435
predicted gene 3435
chr1_-_132390301 0.262 ENSMUST00000132435.1
Tmcc2
transmembrane and coiled-coil domains 2
chr2_+_164948219 0.262 ENSMUST00000017881.2
Mmp9
matrix metallopeptidase 9
chr15_+_84669565 0.259 ENSMUST00000171460.1
Prr5
proline rich 5 (renal)
chr13_-_96471160 0.256 ENSMUST00000055607.5
ENSMUST00000181613.2
Ankdd1b

ankyrin repeat and death domain containing 1B

chr10_+_62920630 0.251 ENSMUST00000044977.3
Slc25a16
solute carrier family 25 (mitochondrial carrier, Graves disease autoantigen), member 16
chr4_+_103313806 0.241 ENSMUST00000035780.3
Oma1
OMA1 homolog, zinc metallopeptidase (S. cerevisiae)
chr17_+_34647128 0.241 ENSMUST00000015605.8
ENSMUST00000182587.1
Atf6b

activating transcription factor 6 beta

chr5_+_30647921 0.237 ENSMUST00000062962.5
Slc35f6
solute carrier family 35, member F6
chr9_+_120577346 0.236 ENSMUST00000064646.4
5830454E08Rik
RIKEN cDNA 5830454E08 gene
chr9_+_109931774 0.232 ENSMUST00000169851.2
Map4
microtubule-associated protein 4
chr17_+_34647187 0.231 ENSMUST00000173984.1
Atf6b
activating transcription factor 6 beta
chr11_-_119228461 0.222 ENSMUST00000036113.3
Tbc1d16
TBC1 domain family, member 16
chr17_+_15053059 0.222 ENSMUST00000040594.8
Ermard
ER membrane associated RNA degradation
chr7_+_127800604 0.221 ENSMUST00000046863.5
ENSMUST00000106272.1
ENSMUST00000139068.1
Hsd3b7


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0061744 motor behavior(GO:0061744) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.7 3.7 GO:0070327 thyroid hormone transport(GO:0070327)
0.5 1.5 GO:0021837 motogenic signaling involved in postnatal olfactory bulb interneuron migration(GO:0021837) positive regulation of mitotic cell cycle DNA replication(GO:1903465)
0.4 1.3 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.4 2.1 GO:0051012 microtubule sliding(GO:0051012)
0.4 2.8 GO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300)
0.4 1.5 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.3 1.3 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.3 1.9 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.3 1.8 GO:0009405 pathogenesis(GO:0009405)
0.3 1.1 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.2 1.9 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.2 1.3 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.2 1.3 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.2 0.8 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.2 0.8 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.2 0.5 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) olefin metabolic process(GO:1900673)
0.2 2.0 GO:0035635 entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.1 0.4 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.1 0.9 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1 0.4 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.1 0.5 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.1 0.6 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.1 1.1 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.1 0.5 GO:0032788 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.1 0.4 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1 0.8 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.1 0.3 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.9 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.6 GO:0072014 proximal tubule development(GO:0072014)
0.1 0.3 GO:2000501 natural killer cell chemotaxis(GO:0035747) negative regulation of lymphocyte migration(GO:2000402) regulation of natural killer cell chemotaxis(GO:2000501)
0.1 1.8 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.1 0.9 GO:0071420 cellular response to histamine(GO:0071420)
0.1 1.4 GO:0099515 actin filament-based transport(GO:0099515)
0.1 0.6 GO:0006172 ADP biosynthetic process(GO:0006172)
0.1 0.5 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.1 1.5 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.1 0.8 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 0.4 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.5 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.3 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.1 1.2 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 1.6 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 0.7 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.1 1.8 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 1.2 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.1 0.5 GO:0097502 mannosylation(GO:0097502)
0.1 0.4 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.1 0.2 GO:0046370 fructose biosynthetic process(GO:0046370)
0.1 0.1 GO:0016139 glycoside catabolic process(GO:0016139)
0.1 0.3 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.3 GO:0051182 coenzyme transport(GO:0051182)
0.1 0.2 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.1 1.3 GO:0030033 microvillus assembly(GO:0030033)
0.1 0.5 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 0.4 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.1 0.2 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.1 1.0 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.4 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.0 0.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.6 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.2 GO:0010637 diet induced thermogenesis(GO:0002024) negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.6 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 1.6 GO:0050729 positive regulation of inflammatory response(GO:0050729)
0.0 0.3 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.5 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.4 GO:0035330 regulation of hippo signaling(GO:0035330)
0.0 0.4 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 0.2 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 3.6 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.1 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.5 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 1.6 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.3 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 1.5 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.2 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0 0.6 GO:0030813 positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.0 0.3 GO:0018916 nitrobenzene metabolic process(GO:0018916)
0.0 1.3 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 1.2 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 2.0 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.3 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.0 0.4 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.0 0.9 GO:0010955 negative regulation of protein processing(GO:0010955) negative regulation of protein maturation(GO:1903318)
0.0 0.3 GO:0038203 TORC2 signaling(GO:0038203)
0.0 1.7 GO:0015807 L-amino acid transport(GO:0015807)
0.0 0.9 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.6 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 0.4 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.0 1.6 GO:0051438 regulation of ubiquitin-protein transferase activity(GO:0051438)
0.0 0.0 GO:0001575 globoside metabolic process(GO:0001575)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 1.0 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 1.1 GO:0043113 receptor clustering(GO:0043113)
0.0 1.2 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.5 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 1.4 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.0 1.5 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.5 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.6 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.5 GO:0090280 positive regulation of calcium ion import(GO:0090280)
0.0 0.8 GO:0007416 synapse assembly(GO:0007416)
0.0 1.7 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.1 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.4 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.4 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.5 GO:0001881 receptor recycling(GO:0001881)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.1 GO:0043267 negative regulation of potassium ion transport(GO:0043267)
0.0 0.9 GO:0060998 regulation of dendritic spine development(GO:0060998)
0.0 0.8 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.2 1.5 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 2.0 GO:0042581 specific granule(GO:0042581)
0.1 1.6 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 0.6 GO:0097441 basilar dendrite(GO:0097441)
0.1 0.3 GO:0045160 myosin I complex(GO:0045160)
0.1 2.0 GO:0000145 exocyst(GO:0000145)
0.1 1.5 GO:0044754 secondary lysosome(GO:0005767) autolysosome(GO:0044754)
0.1 0.4 GO:0043293 apoptosome(GO:0043293)
0.1 1.9 GO:0097228 sperm principal piece(GO:0097228)
0.1 1.8 GO:0071564 npBAF complex(GO:0071564)
0.1 0.8 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1 1.2 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.6 GO:0001520 outer dense fiber(GO:0001520)
0.1 0.7 GO:0002177 manchette(GO:0002177)
0.1 0.6 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 0.9 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 0.9 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 0.3 GO:1990357 terminal web(GO:1990357)
0.1 0.4 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.4 GO:0042825 TAP complex(GO:0042825)
0.0 1.2 GO:0005771 multivesicular body(GO:0005771)
0.0 1.2 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.6 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.8 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.9 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.2 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.0 1.3 GO:0032040 small-subunit processome(GO:0032040)
0.0 1.0 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.4 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 1.2 GO:0030673 axolemma(GO:0030673)
0.0 1.3 GO:0031941 filamentous actin(GO:0031941)
0.0 1.8 GO:0005581 collagen trimer(GO:0005581)
0.0 0.4 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.5 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.7 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.6 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.3 GO:0031932 TORC2 complex(GO:0031932)
0.0 1.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.1 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.7 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.2 GO:0016605 PML body(GO:0016605)
0.0 0.5 GO:0044295 axonal growth cone(GO:0044295)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.4 2.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.4 3.7 GO:0070324 thyroid hormone binding(GO:0070324)
0.3 1.0 GO:0004658 propionyl-CoA carboxylase activity(GO:0004658)
0.3 1.3 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.3 0.8 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.3 0.8 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.3 1.3 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 0.9 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.2 0.7 GO:0001729 ceramide kinase activity(GO:0001729)
0.2 1.0 GO:0032027 myosin light chain binding(GO:0032027)
0.2 2.3 GO:0015643 toxic substance binding(GO:0015643)
0.2 1.5 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 0.5 GO:0030350 iron-responsive element binding(GO:0030350)
0.1 2.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.6 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.6 GO:0070330 aromatase activity(GO:0070330)
0.1 0.4 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 0.3 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 1.7 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 1.2 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1 0.4 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 1.9 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.6 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 1.2 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.1 0.3 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 0.5 GO:0046790 virion binding(GO:0046790)
0.1 0.7 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.4 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 3.9 GO:0001221 transcription cofactor binding(GO:0001221)
0.1 0.2 GO:0046997 sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.1 0.4 GO:0046978 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.1 0.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 1.5 GO:0008373 sialyltransferase activity(GO:0008373)
0.1 0.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 0.3 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.6 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.3 GO:0051185 coenzyme transporter activity(GO:0051185)
0.1 1.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 2.4 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 2.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.2 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.5 GO:0015250 water channel activity(GO:0015250)
0.0 1.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.9 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.2 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 1.7 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.1 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.3 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.0 0.1 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.7 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.5 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.4 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.3 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.5 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.5 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.4 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.5 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 1.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.3 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 1.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.5 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.8 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.1 GO:0031432 titin binding(GO:0031432)
0.0 1.1 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.8 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.3 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.0 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
0.0 0.0 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.4 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.6 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.1 1.8 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.0 0.8 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.7 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 1.2 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 0.3 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.0 1.1 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 2.4 PID_CMYB_PATHWAY C-MYB transcription factor network
0.0 0.5 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.4 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.0 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 0.6 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.1 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.4 PID_ARF_3PATHWAY Arf1 pathway
0.0 0.5 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.0 1.2 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 2.2 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.8 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.8 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 1.5 REACTOME_SIGNALING_BY_ACTIVATED_POINT_MUTANTS_OF_FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.1 2.6 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 2.2 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.1 2.8 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.1 1.3 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.1 1.4 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 1.3 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.1 1.3 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 2.3 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.0 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 2.0 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 2.2 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.2 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.6 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.4 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 1.6 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.6 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.0 1.1 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.5 REACTOME_SIGNALING_BY_NOTCH4 Genes involved in Signaling by NOTCH4
0.0 0.4 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.2 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.3 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.6 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.6 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.6 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.5 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.7 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.4 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.0 0.6 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.6 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.5 REACTOME_DOWNSTREAM_TCR_SIGNALING Genes involved in Downstream TCR signaling
0.0 0.4 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.1 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.1 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB