Motif ID: Tbx15

Z-value: 0.702


Transcription factors associated with Tbx15:

Gene SymbolEntrez IDGene Name
Tbx15 ENSMUSG00000027868.5 Tbx15



Activity profile for motif Tbx15.

activity profile for motif Tbx15


Sorted Z-values histogram for motif Tbx15

Sorted Z-values for motif Tbx15



Network of associatons between targets according to the STRING database.



First level regulatory network of Tbx15

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_48045144 7.702 ENSMUST00000030025.3
Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr6_+_108213086 3.983 ENSMUST00000032192.6
Itpr1
inositol 1,4,5-trisphosphate receptor 1
chr17_-_81649607 3.640 ENSMUST00000163680.2
ENSMUST00000086538.3
ENSMUST00000163123.1
Slc8a1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr19_-_10304867 3.452 ENSMUST00000039327.4
Dagla
diacylglycerol lipase, alpha
chr12_-_78980758 3.089 ENSMUST00000174072.1
Tmem229b
transmembrane protein 229B
chr4_-_129121889 2.907 ENSMUST00000139450.1
ENSMUST00000125931.1
ENSMUST00000116444.2
Hpca


hippocalcin


chr16_-_23988852 2.655 ENSMUST00000023151.5
Bcl6
B cell leukemia/lymphoma 6
chr16_-_43979050 2.422 ENSMUST00000165648.1
ENSMUST00000036321.7
Zdhhc23

zinc finger, DHHC domain containing 23

chr11_+_83302817 2.411 ENSMUST00000142680.1
Ap2b1
adaptor-related protein complex 2, beta 1 subunit
chr7_-_78577771 2.337 ENSMUST00000039438.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr4_+_53440388 2.314 ENSMUST00000102911.3
ENSMUST00000107646.2
Slc44a1

solute carrier family 44, member 1

chr7_-_78578308 2.311 ENSMUST00000039431.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr5_+_32136458 2.296 ENSMUST00000031017.9
Fosl2
fos-like antigen 2
chr14_-_30353468 2.263 ENSMUST00000112249.1
Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr7_-_24316590 2.197 ENSMUST00000108436.1
ENSMUST00000032673.8
Zfp94

zinc finger protein 94

chr11_+_84179792 2.143 ENSMUST00000137500.2
ENSMUST00000130012.2
Acaca

acetyl-Coenzyme A carboxylase alpha

chrX_+_41401128 2.108 ENSMUST00000115103.2
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr8_-_8639363 2.065 ENSMUST00000152698.1
Efnb2
ephrin B2
chr11_+_83302641 2.061 ENSMUST00000176430.1
ENSMUST00000065692.7
Ap2b1

adaptor-related protein complex 2, beta 1 subunit

chr7_-_132813715 2.055 ENSMUST00000134946.1
Fam53b
family with sequence similarity 53, member B
chr7_+_30169861 2.049 ENSMUST00000085668.4
Gm5113
predicted gene 5113
chr9_-_49798905 1.992 ENSMUST00000114476.2
Ncam1
neural cell adhesion molecule 1
chr19_-_28963863 1.980 ENSMUST00000161813.1
4430402I18Rik
RIKEN cDNA 4430402I18 gene
chrX_+_159840463 1.959 ENSMUST00000112451.1
ENSMUST00000112453.2
Sh3kbp1

SH3-domain kinase binding protein 1

chr2_+_91945703 1.952 ENSMUST00000178895.1
Gm9821
predicted gene 9821
chr18_+_36559972 1.951 ENSMUST00000134146.1
Ankhd1
ankyrin repeat and KH domain containing 1
chr11_+_3330781 1.929 ENSMUST00000136536.1
ENSMUST00000093399.4
Pik3ip1

phosphoinositide-3-kinase interacting protein 1

chr19_-_37207293 1.905 ENSMUST00000132580.1
ENSMUST00000079754.4
ENSMUST00000136286.1
ENSMUST00000126188.1
ENSMUST00000126781.1
Cpeb3




cytoplasmic polyadenylation element binding protein 3




chr2_+_68861564 1.899 ENSMUST00000176018.1
Cers6
ceramide synthase 6
chr8_+_84723003 1.891 ENSMUST00000098571.4
G430095P16Rik
RIKEN cDNA G430095P16 gene
chr6_+_115134899 1.862 ENSMUST00000009538.5
ENSMUST00000169345.1
Syn2

synapsin II

chr7_-_98162318 1.769 ENSMUST00000107112.1
Capn5
calpain 5
chr17_-_6449571 1.762 ENSMUST00000180035.1
Tmem181b-ps
transmembrane protein 181B, pseudogene
chr6_+_114131229 1.749 ENSMUST00000032451.7
Slc6a11
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
chr4_-_151108244 1.729 ENSMUST00000131948.1
Camta1
calmodulin binding transcription activator 1
chr3_-_94582548 1.707 ENSMUST00000107283.1
Snx27
sorting nexin family member 27
chr16_+_72663143 1.642 ENSMUST00000023600.7
Robo1
roundabout homolog 1 (Drosophila)
chr7_+_30291659 1.630 ENSMUST00000014065.8
ENSMUST00000150892.1
ENSMUST00000126216.1
Clip3


CAP-GLY domain containing linker protein 3


chr1_-_133025330 1.620 ENSMUST00000067429.3
ENSMUST00000067398.6
Mdm4

transformed mouse 3T3 cell double minute 4

chr14_-_55116935 1.588 ENSMUST00000022819.5
Jph4
junctophilin 4
chr6_-_82939676 1.564 ENSMUST00000000641.9
ENSMUST00000113982.1
Sema4f

sema domain, immunoglobulin domain (Ig), TM domain, and short cytoplasmic domain

chr6_-_28831747 1.559 ENSMUST00000062304.5
Lrrc4
leucine rich repeat containing 4
chr14_-_100149764 1.529 ENSMUST00000097079.4
Klf12
Kruppel-like factor 12
chr15_+_57694651 1.520 ENSMUST00000096430.4
Zhx2
zinc fingers and homeoboxes 2
chr9_+_27299205 1.519 ENSMUST00000115247.1
ENSMUST00000133213.1
Igsf9b

immunoglobulin superfamily, member 9B

chr5_-_8367982 1.491 ENSMUST00000088761.4
ENSMUST00000115386.1
ENSMUST00000050166.7
ENSMUST00000046838.7
ENSMUST00000115388.2
ENSMUST00000088744.5
ENSMUST00000115385.1
Adam22






a disintegrin and metallopeptidase domain 22






chr17_-_6621267 1.454 ENSMUST00000115772.3
Tmem181c-ps
transmembrane protein 181C, pseudogene
chr1_+_170214826 1.439 ENSMUST00000159201.1
ENSMUST00000055830.1
4930500M09Rik

RIKEN cDNA 4930500M09 gene

chr9_-_122862128 1.438 ENSMUST00000056467.7
Zfp445
zinc finger protein 445
chr11_-_116654245 1.416 ENSMUST00000021166.5
Cygb
cytoglobin
chrX_+_41401304 1.390 ENSMUST00000076349.5
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr7_-_28379247 1.373 ENSMUST00000051241.5
Zfp36
zinc finger protein 36
chr12_+_33314277 1.356 ENSMUST00000133549.1
Atxn7l1
ataxin 7-like 1
chr4_+_144893127 1.340 ENSMUST00000142808.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr17_-_37023349 1.317 ENSMUST00000102665.4
Mog
myelin oligodendrocyte glycoprotein
chr9_-_49798729 1.317 ENSMUST00000166811.2
Ncam1
neural cell adhesion molecule 1
chr3_+_96181151 1.314 ENSMUST00000035371.8
Sv2a
synaptic vesicle glycoprotein 2 a
chr13_-_43304153 1.279 ENSMUST00000055341.5
Gfod1
glucose-fructose oxidoreductase domain containing 1
chr4_+_148000722 1.277 ENSMUST00000103230.4
Nppa
natriuretic peptide type A
chr7_+_46396439 1.239 ENSMUST00000025202.6
Kcnc1
potassium voltage gated channel, Shaw-related subfamily, member 1
chr9_+_95954744 1.235 ENSMUST00000034981.7
Xrn1
5'-3' exoribonuclease 1
chr7_+_79810727 1.230 ENSMUST00000107394.1
Mesp2
mesoderm posterior 2
chr3_-_84220853 1.219 ENSMUST00000154152.1
ENSMUST00000107693.2
ENSMUST00000107695.2
Trim2


tripartite motif-containing 2


chr4_+_53440516 1.217 ENSMUST00000107651.2
ENSMUST00000107647.1
Slc44a1

solute carrier family 44, member 1

chr14_+_45351473 1.195 ENSMUST00000111835.2
Styx
serine/threonine/tyrosine interaction protein
chr2_-_91183017 1.188 ENSMUST00000066420.5
Madd
MAP-kinase activating death domain
chr3_+_55461758 1.178 ENSMUST00000070418.4
Dclk1
doublecortin-like kinase 1
chr3_-_82074639 1.164 ENSMUST00000029635.8
Gucy1b3
guanylate cyclase 1, soluble, beta 3
chrX_-_150657366 1.163 ENSMUST00000148604.1
Tro
trophinin
chr8_+_83900706 1.155 ENSMUST00000045393.8
ENSMUST00000132500.1
ENSMUST00000152978.1
Lphn1


latrophilin 1


chr2_-_44927161 1.127 ENSMUST00000130991.1
Gtdc1
glycosyltransferase-like domain containing 1
chr15_+_103503261 1.126 ENSMUST00000023132.3
Pde1b
phosphodiesterase 1B, Ca2+-calmodulin dependent
chr4_-_129121699 1.123 ENSMUST00000135763.1
ENSMUST00000149763.1
ENSMUST00000164649.1
Hpca


hippocalcin


chr16_-_32868325 1.113 ENSMUST00000089684.3
ENSMUST00000040986.8
ENSMUST00000115105.2
1700021K19Rik


RIKEN cDNA 1700021K19 gene


chr8_+_79028587 1.108 ENSMUST00000119254.1
Zfp827
zinc finger protein 827
chr12_+_88953399 1.106 ENSMUST00000057634.7
Nrxn3
neurexin III
chr13_+_29014399 1.095 ENSMUST00000146336.1
ENSMUST00000130109.1
A330102I10Rik

RIKEN cDNA A330102I10 gene

chr3_+_75557530 1.090 ENSMUST00000161776.1
ENSMUST00000029423.8
Serpini1

serine (or cysteine) peptidase inhibitor, clade I, member 1

chr5_+_111733924 1.087 ENSMUST00000180627.1
Gm26897
predicted gene, 26897
chr7_-_80688852 1.084 ENSMUST00000122255.1
Crtc3
CREB regulated transcription coactivator 3
chr12_-_3426700 1.078 ENSMUST00000180149.1
1110002L01Rik
RIKEN cDNA 1110002L01 gene
chr3_-_94582716 1.078 ENSMUST00000029783.9
Snx27
sorting nexin family member 27
chr11_-_120630126 1.064 ENSMUST00000106180.1
Mafg
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr4_+_125490688 1.061 ENSMUST00000030676.7
Grik3
glutamate receptor, ionotropic, kainate 3
chr9_-_44721383 1.043 ENSMUST00000148929.1
ENSMUST00000123406.1
Phldb1

pleckstrin homology-like domain, family B, member 1

chr12_+_102948843 1.037 ENSMUST00000101099.5
Unc79
unc-79 homolog (C. elegans)
chr13_+_54503779 1.037 ENSMUST00000121401.1
ENSMUST00000118072.1
ENSMUST00000159721.1
Simc1


SUMO-interacting motifs containing 1


chr1_+_156558844 1.026 ENSMUST00000166172.2
ENSMUST00000027888.6
Abl2

v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene)

chr2_+_164823001 1.024 ENSMUST00000132282.1
Zswim1
zinc finger SWIM-type containing 1
chr2_+_32609043 1.020 ENSMUST00000128811.1
St6galnac6
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr18_+_37294840 1.014 ENSMUST00000056522.3
Pcdhb2
protocadherin beta 2
chr10_-_127263346 1.004 ENSMUST00000099172.3
Kif5a
kinesin family member 5A
chr13_+_80886095 1.000 ENSMUST00000161441.1
Arrdc3
arrestin domain containing 3
chr13_+_109685994 0.994 ENSMUST00000074103.5
Pde4d
phosphodiesterase 4D, cAMP specific
chr4_-_82505749 0.985 ENSMUST00000107245.2
ENSMUST00000107246.1
Nfib

nuclear factor I/B

chr11_+_23306910 0.983 ENSMUST00000137823.1
Usp34
ubiquitin specific peptidase 34
chr19_-_57008187 0.978 ENSMUST00000118800.1
ENSMUST00000111584.2
ENSMUST00000122359.1
ENSMUST00000148049.1
Afap1l2



actin filament associated protein 1-like 2



chr9_-_4796218 0.977 ENSMUST00000027020.6
ENSMUST00000063508.7
ENSMUST00000163309.1
Gria4


glutamate receptor, ionotropic, AMPA4 (alpha 4)


chr1_-_40790642 0.971 ENSMUST00000039672.5
Mfsd9
major facilitator superfamily domain containing 9
chr12_+_105336922 0.969 ENSMUST00000180503.1
2810011L19Rik
RIKEN cDNA 2810011L19 gene
chr9_+_31280525 0.954 ENSMUST00000117389.1
Prdm10
PR domain containing 10
chr11_+_121237216 0.942 ENSMUST00000103015.3
Narf
nuclear prelamin A recognition factor
chr13_+_96542602 0.940 ENSMUST00000179226.1
Col4a3bp
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
chr5_-_84417359 0.938 ENSMUST00000113401.1
Epha5
Eph receptor A5
chr8_+_23035116 0.933 ENSMUST00000117296.1
ENSMUST00000141784.2
Ank1

ankyrin 1, erythroid

chr16_-_50330987 0.927 ENSMUST00000114488.1
Bbx
bobby sox homolog (Drosophila)
chr5_-_148371525 0.926 ENSMUST00000138596.1
Slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr9_+_103008479 0.919 ENSMUST00000035148.6
Slco2a1
solute carrier organic anion transporter family, member 2a1
chr7_-_126897424 0.913 ENSMUST00000120007.1
Tmem219
transmembrane protein 219
chr9_+_46998931 0.909 ENSMUST00000178065.1
Gm4791
predicted gene 4791
chr11_-_98149551 0.896 ENSMUST00000103143.3
Fbxl20
F-box and leucine-rich repeat protein 20
chr11_+_53519920 0.896 ENSMUST00000147912.1
Sept8
septin 8
chr4_-_129440800 0.891 ENSMUST00000053042.5
ENSMUST00000106046.1
Zbtb8b

zinc finger and BTB domain containing 8b

chr9_-_20879718 0.890 ENSMUST00000043726.6
Angptl6
angiopoietin-like 6
chr11_-_120630516 0.889 ENSMUST00000106181.1
Mafg
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr7_+_130936172 0.883 ENSMUST00000006367.7
Htra1
HtrA serine peptidase 1
chr1_-_63114255 0.864 ENSMUST00000153992.1
ENSMUST00000165066.1
ENSMUST00000172416.1
ENSMUST00000137511.1
Ino80d



INO80 complex subunit D



chr2_-_91182848 0.858 ENSMUST00000111370.2
ENSMUST00000111376.1
ENSMUST00000099723.2
Madd


MAP-kinase activating death domain


chr12_+_3426857 0.850 ENSMUST00000111215.3
ENSMUST00000092003.5
ENSMUST00000144247.2
ENSMUST00000153102.2
Asxl2



additional sex combs like 2 (Drosophila)



chrX_-_101420348 0.838 ENSMUST00000119699.1
Zmym3
zinc finger, MYM-type 3
chr11_+_53519871 0.837 ENSMUST00000120878.2
Sept8
septin 8
chr18_+_37473538 0.836 ENSMUST00000050034.1
Pcdhb15
protocadherin beta 15
chr11_+_69901816 0.836 ENSMUST00000177138.1
ENSMUST00000108617.3
ENSMUST00000177476.1
ENSMUST00000061837.4
Neurl4



neuralized homolog 4 (Drosophila)



chr8_-_122915987 0.825 ENSMUST00000098333.4
Ankrd11
ankyrin repeat domain 11
chr11_-_83302586 0.820 ENSMUST00000176374.1
Pex12
peroxisomal biogenesis factor 12
chr1_+_194619815 0.819 ENSMUST00000027952.5
Plxna2
plexin A2
chr10_+_123264076 0.818 ENSMUST00000050756.7
Fam19a2
family with sequence similarity 19, member A2
chr8_-_125898291 0.815 ENSMUST00000047239.6
Pcnxl2
pecanex-like 2 (Drosophila)
chr2_+_68861433 0.814 ENSMUST00000028426.2
Cers6
ceramide synthase 6
chr5_-_148399901 0.814 ENSMUST00000048116.8
Slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr15_-_71727815 0.812 ENSMUST00000022953.8
Fam135b
family with sequence similarity 135, member B
chr10_-_81472859 0.810 ENSMUST00000147524.1
ENSMUST00000119060.1
Celf5

CUGBP, Elav-like family member 5

chr17_+_35135463 0.809 ENSMUST00000173535.1
ENSMUST00000173952.1
Bag6

BCL2-associated athanogene 6

chr18_-_54990124 0.808 ENSMUST00000064763.5
Zfp608
zinc finger protein 608
chr2_+_102659213 0.807 ENSMUST00000111213.1
Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chrX_-_59567348 0.805 ENSMUST00000124402.1
Fgf13
fibroblast growth factor 13
chr9_-_62070606 0.804 ENSMUST00000034785.7
Glce
glucuronyl C5-epimerase
chr2_-_132145057 0.798 ENSMUST00000028815.8
Slc23a2
solute carrier family 23 (nucleobase transporters), member 2
chr6_+_42286709 0.790 ENSMUST00000163936.1
Clcn1
chloride channel 1
chr18_-_42899294 0.780 ENSMUST00000117687.1
Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chrX_-_101419788 0.779 ENSMUST00000117901.1
ENSMUST00000120201.1
ENSMUST00000117637.1
ENSMUST00000134005.1
ENSMUST00000121520.1
Zmym3




zinc finger, MYM-type 3




chr9_+_108991902 0.769 ENSMUST00000147989.1
ENSMUST00000051873.8
Pfkfb4

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4

chr11_+_98741871 0.758 ENSMUST00000103139.4
Thra
thyroid hormone receptor alpha
chr1_+_180726019 0.758 ENSMUST00000027780.4
Acbd3
acyl-Coenzyme A binding domain containing 3
chr2_+_136891501 0.755 ENSMUST00000141463.1
Slx4ip
SLX4 interacting protein
chr15_-_12592556 0.753 ENSMUST00000075317.5
Pdzd2
PDZ domain containing 2
chrX_+_153359613 0.753 ENSMUST00000039545.4
Klf8
Kruppel-like factor 8
chr6_-_92214897 0.745 ENSMUST00000014694.8
Zfyve20
zinc finger, FYVE domain containing 20
chr15_+_8169067 0.727 ENSMUST00000110617.1
2410089E03Rik
RIKEN cDNA 2410089E03 gene
chr8_+_4243264 0.721 ENSMUST00000110996.1
Map2k7
mitogen-activated protein kinase kinase 7
chr3_-_89773221 0.718 ENSMUST00000038450.1
4632404H12Rik
RIKEN cDNA 4632404H12 gene
chr4_+_139923349 0.714 ENSMUST00000128563.1
Gm13028
predicted gene 13028
chr18_+_65582390 0.713 ENSMUST00000169679.1
ENSMUST00000183326.1
Zfp532

zinc finger protein 532

chr5_+_107331157 0.712 ENSMUST00000031215.8
ENSMUST00000112677.3
Brdt

bromodomain, testis-specific

chr15_-_81360739 0.710 ENSMUST00000023040.7
Slc25a17
solute carrier family 25 (mitochondrial carrier, peroxisomal membrane protein), member 17
chr7_-_30169701 0.703 ENSMUST00000062181.7
Zfp146
zinc finger protein 146
chr6_+_48395652 0.697 ENSMUST00000077093.4
Krba1
KRAB-A domain containing 1
chr10_+_75212065 0.695 ENSMUST00000105421.2
Specc1l
sperm antigen with calponin homology and coiled-coil domains 1-like
chrX_-_101420206 0.689 ENSMUST00000118092.1
Zmym3
zinc finger, MYM-type 3
chr14_-_64949632 0.676 ENSMUST00000176832.1
Hmbox1
homeobox containing 1
chr3_+_51483966 0.676 ENSMUST00000054387.6
Rab33b
RAB33B, member of RAS oncogene family
chr8_-_105933832 0.675 ENSMUST00000034368.6
Ctrl
chymotrypsin-like
chr13_-_8871751 0.674 ENSMUST00000175958.1
Wdr37
WD repeat domain 37
chr9_-_89622986 0.673 ENSMUST00000044491.6
AF529169
cDNA sequence AF529169
chr7_-_113369326 0.669 ENSMUST00000047091.7
ENSMUST00000119278.1
Btbd10

BTB (POZ) domain containing 10

chr18_-_12236301 0.669 ENSMUST00000025279.5
Npc1
Niemann Pick type C1
chrM_+_9870 0.665 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr1_-_105356658 0.662 ENSMUST00000058688.5
ENSMUST00000172299.1
Rnf152

ring finger protein 152

chr9_-_73039644 0.658 ENSMUST00000184389.1
Pigb
phosphatidylinositol glycan anchor biosynthesis, class B
chr5_+_143622466 0.658 ENSMUST00000177196.1
Cyth3
cytohesin 3
chr6_+_39573858 0.652 ENSMUST00000140364.1
Adck2
aarF domain containing kinase 2
chr11_+_98348404 0.651 ENSMUST00000078694.6
Ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr3_-_96905294 0.646 ENSMUST00000029738.7
Gpr89
G protein-coupled receptor 89
chr15_-_82912134 0.636 ENSMUST00000048966.5
ENSMUST00000109510.2
Tcf20

transcription factor 20

chr7_+_130577334 0.627 ENSMUST00000059145.7
ENSMUST00000084513.4
Tacc2

transforming, acidic coiled-coil containing protein 2

chr4_-_126753372 0.621 ENSMUST00000030637.7
ENSMUST00000106116.1
Ncdn

neurochondrin

chrX_-_150657392 0.611 ENSMUST00000151403.2
ENSMUST00000087253.4
ENSMUST00000112709.1
ENSMUST00000163969.1
ENSMUST00000087258.3
Tro




trophinin




chr17_+_47630690 0.609 ENSMUST00000024779.8
Usp49
ubiquitin specific peptidase 49
chr2_-_45117349 0.607 ENSMUST00000176438.2
Zeb2
zinc finger E-box binding homeobox 2
chrX_+_166238923 0.592 ENSMUST00000060210.7
ENSMUST00000112233.1
Gpm6b

glycoprotein m6b

chr16_+_23107413 0.590 ENSMUST00000023599.6
ENSMUST00000168891.1
Eif4a2

eukaryotic translation initiation factor 4A2

chr14_-_55106547 0.588 ENSMUST00000036041.8
Ap1g2
adaptor protein complex AP-1, gamma 2 subunit
chr1_-_24612700 0.587 ENSMUST00000088336.1
Gm10222
predicted gene 10222
chr19_-_46327121 0.585 ENSMUST00000041391.4
ENSMUST00000096029.5
Psd

pleckstrin and Sec7 domain containing

chr12_+_51348265 0.583 ENSMUST00000119211.1
G2e3
G2/M-phase specific E3 ubiquitin ligase
chrX_-_7947763 0.574 ENSMUST00000154244.1
Hdac6
histone deacetylase 6
chr12_+_51348370 0.573 ENSMUST00000121521.1
G2e3
G2/M-phase specific E3 ubiquitin ligase
chr7_+_126928844 0.571 ENSMUST00000032924.5
Kctd13
potassium channel tetramerisation domain containing 13
chr7_+_18987518 0.567 ENSMUST00000063563.7
Nanos2
nanos homolog 2 (Drosophila)
chr15_-_79164477 0.564 ENSMUST00000040019.4
Sox10
SRY-box containing gene 10
chr9_-_73039697 0.560 ENSMUST00000184035.1
ENSMUST00000098566.4
Pigb

phosphatidylinositol glycan anchor biosynthesis, class B

chr7_+_25282784 0.553 ENSMUST00000165239.1
Cic
capicua homolog (Drosophila)
chr5_-_31048014 0.551 ENSMUST00000137223.1
Slc5a6
solute carrier family 5 (sodium-dependent vitamin transporter), member 6
chr6_+_39573894 0.549 ENSMUST00000051249.6
Adck2
aarF domain containing kinase 2
chr2_-_64975762 0.546 ENSMUST00000156765.1
Grb14
growth factor receptor bound protein 14
chr11_-_97575210 0.543 ENSMUST00000107596.2
Srcin1
SRC kinase signaling inhibitor 1
chr6_+_42286676 0.538 ENSMUST00000031894.6
Clcn1
chloride channel 1
chrX_+_152016428 0.535 ENSMUST00000045312.5
Smc1a
structural maintenance of chromosomes 1A
chr11_+_70018728 0.528 ENSMUST00000018700.6
ENSMUST00000134376.2
Dlg4

discs, large homolog 4 (Drosophila)

chr18_+_76241892 0.522 ENSMUST00000171256.1
Smad2
SMAD family member 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.7 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
1.5 4.6 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
1.3 4.0 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
1.3 2.7 GO:0032763 regulation of mast cell cytokine production(GO:0032763)
1.2 1.2 GO:0099548 trans-synaptic signaling by nitric oxide(GO:0099548)
1.2 3.5 GO:0046340 diacylglycerol catabolic process(GO:0046340)
1.1 3.3 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.7 3.6 GO:0098735 cellular response to caffeine(GO:0071313) positive regulation of the force of heart contraction(GO:0098735)
0.7 3.5 GO:0015871 choline transport(GO:0015871)
0.7 2.0 GO:1902277 negative regulation of pancreatic amylase secretion(GO:1902277)
0.7 4.0 GO:0042045 epithelial fluid transport(GO:0042045)
0.6 1.9 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.6 2.3 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.5 1.6 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.5 2.1 GO:0044268 multicellular organismal protein metabolic process(GO:0044268)
0.5 4.5 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.5 1.4 GO:1904580 regulation of polynucleotide adenylyltransferase activity(GO:1904245) regulation of intracellular mRNA localization(GO:1904580)
0.4 1.3 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.4 1.2 GO:0035621 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
0.4 1.2 GO:0045204 MAPK export from nucleus(GO:0045204)
0.3 1.0 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879) negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.3 1.3 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.3 1.2 GO:0008078 mesodermal cell migration(GO:0008078)
0.3 1.4 GO:0015671 oxygen transport(GO:0015671)
0.3 1.9 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.3 0.8 GO:0030210 heparin biosynthetic process(GO:0030210)
0.3 0.8 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.3 2.1 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.2 1.0 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.2 0.9 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.2 0.7 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.2 1.0 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.2 0.6 GO:0070844 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.2 1.6 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.2 0.8 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.2 1.2 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.2 1.1 GO:0036006 response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
0.2 0.5 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.2 0.7 GO:0045054 constitutive secretory pathway(GO:0045054)
0.2 1.1 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 0.9 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.1 0.6 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 1.0 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 0.4 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.1 0.6 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 1.5 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.1 1.5 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.1 1.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.8 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 0.7 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 1.3 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 1.3 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.1 2.8 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.1 1.0 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.1 0.2 GO:0045963 negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963)
0.1 0.4 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 0.6 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 0.7 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 2.3 GO:0003334 keratinocyte development(GO:0003334)
0.1 1.6 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.1 0.5 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335) positive regulation of G0 to G1 transition(GO:0070318)
0.1 0.9 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1 1.7 GO:0015809 arginine transport(GO:0015809)
0.1 1.0 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 0.3 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.1 1.0 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.5 GO:0003192 mitral valve formation(GO:0003192) cell migration involved in endocardial cushion formation(GO:0003273) condensed mesenchymal cell proliferation(GO:0072137)
0.1 0.6 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.1 1.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 0.3 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 1.4 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.6 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.1 0.8 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 1.2 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.1 1.0 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.1 0.8 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 0.5 GO:0019236 response to pheromone(GO:0019236)
0.1 2.4 GO:0018345 protein palmitoylation(GO:0018345)
0.1 0.4 GO:0006868 glutamine transport(GO:0006868)
0.1 0.5 GO:0072396 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.1 0.3 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 0.7 GO:0036506 maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1 1.1 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.1 1.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.3 GO:0002158 osteoclast proliferation(GO:0002158)
0.1 0.5 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.1 3.4 GO:0001919 regulation of receptor recycling(GO:0001919)
0.1 0.5 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.1 0.5 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 0.9 GO:0099628 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628) regulation of grooming behavior(GO:2000821)
0.1 0.9 GO:0015732 prostaglandin transport(GO:0015732)
0.1 1.0 GO:1901898 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 1.6 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.1 0.4 GO:0035878 nail development(GO:0035878)
0.1 0.7 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.1 0.8 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1 0.4 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.6 GO:0030953 astral microtubule organization(GO:0030953)
0.1 1.6 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.3 GO:0007625 grooming behavior(GO:0007625)
0.1 0.3 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.7 GO:0007141 male meiosis I(GO:0007141)
0.1 0.9 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.1 0.4 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.0 1.0 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0 1.5 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 1.6 GO:0030517 negative regulation of axon extension(GO:0030517)
0.0 0.3 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 1.8 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.2 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.1 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.3 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 3.7 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.8 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.3 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.0 0.2 GO:0032275 luteinizing hormone secretion(GO:0032275) positive regulation of gonadotropin secretion(GO:0032278)
0.0 0.6 GO:0097502 mannosylation(GO:0097502)
0.0 0.3 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.2 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.1 GO:1902044 regulation of Fas signaling pathway(GO:1902044) negative regulation of Fas signaling pathway(GO:1902045)
0.0 0.6 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.1 GO:0046013 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.2 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 1.2 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
0.0 2.1 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.2 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.7 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.1 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.0 0.2 GO:0006551 leucine metabolic process(GO:0006551)
0.0 0.8 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.3 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 1.0 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.4 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 0.3 GO:0042182 ketone catabolic process(GO:0042182)
0.0 0.3 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0 0.1 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 0.7 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.1 GO:1904395 regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) positive regulation of neuromuscular junction development(GO:1904398)
0.0 0.1 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) protein K29-linked ubiquitination(GO:0035519)
0.0 0.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.5 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.1 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0 0.3 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.6 GO:0051452 intracellular pH reduction(GO:0051452)
0.0 0.0 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.7 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.1 GO:0006447 regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994)
0.0 0.4 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.2 GO:0009048 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.2 GO:0030813 positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.0 0.1 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.2 GO:0090031 positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.0 0.3 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.7 GO:0015908 fatty acid transport(GO:0015908)
0.0 1.2 GO:0001824 blastocyst development(GO:0001824)
0.0 0.2 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.2 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 0.9 GO:0048675 axon extension(GO:0048675)
0.0 0.2 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 1.9 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.3 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.3 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.6 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.1 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.4 GO:0015844 monoamine transport(GO:0015844)
0.0 0.3 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0031088 platelet dense granule membrane(GO:0031088)
0.4 2.8 GO:0071203 WASH complex(GO:0071203)
0.4 0.4 GO:0030128 clathrin coat of endocytic vesicle(GO:0030128) clathrin-coated endocytic vesicle membrane(GO:0030669)
0.3 1.6 GO:0030314 junctional membrane complex(GO:0030314)
0.3 4.0 GO:0044327 dendritic spine head(GO:0044327)
0.3 1.1 GO:0031983 vesicle lumen(GO:0031983)
0.2 3.5 GO:0043083 synaptic cleft(GO:0043083)
0.2 2.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 0.9 GO:0032444 activin responsive factor complex(GO:0032444)
0.2 0.8 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.2 3.1 GO:0043196 varicosity(GO:0043196)
0.2 3.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 5.5 GO:0030673 axolemma(GO:0030673)
0.1 0.9 GO:0005638 lamin filament(GO:0005638)
0.1 0.7 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 5.1 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 0.7 GO:0005796 Golgi lumen(GO:0005796)
0.1 0.9 GO:0042629 mast cell granule(GO:0042629)
0.1 0.5 GO:0030893 meiotic cohesin complex(GO:0030893)
0.1 0.7 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 1.9 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.4 GO:0035339 SPOTS complex(GO:0035339)
0.1 2.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 1.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.8 GO:0070545 PeBoW complex(GO:0070545)
0.1 1.0 GO:0045180 basal cortex(GO:0045180)
0.1 1.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 1.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 1.0 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.6 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.4 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 1.5 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.3 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 3.6 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.4 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.5 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 1.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.5 GO:0031201 SNARE complex(GO:0031201)
0.0 1.4 GO:0016235 aggresome(GO:0016235)
0.0 0.7 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.1 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.3 GO:0090543 Flemming body(GO:0090543)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.8 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 1.6 GO:0005657 replication fork(GO:0005657)
0.0 0.9 GO:0035869 ciliary transition zone(GO:0035869)
0.0 5.5 GO:0043209 myelin sheath(GO:0043209)
0.0 2.7 GO:0043197 dendritic spine(GO:0043197)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.5 GO:0045177 apical part of cell(GO:0045177)
0.0 0.7 GO:0031941 filamentous actin(GO:0031941)
0.0 1.8 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.1 GO:0001533 cornified envelope(GO:0001533)
0.0 0.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.8 GO:0031526 brush border membrane(GO:0031526)
0.0 2.0 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.5 GO:0016592 mediator complex(GO:0016592)
0.0 2.7 GO:0043235 receptor complex(GO:0043235)
0.0 1.9 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.2 GO:0035098 ESC/E(Z) complex(GO:0035098)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.9 4.6 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.9 3.5 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.9 3.5 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.7 2.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.6 1.9 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.6 4.5 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.6 1.7 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.5 2.9 GO:0097001 ceramide binding(GO:0097001)
0.4 1.3 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.4 1.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.4 1.4 GO:0004096 catalase activity(GO:0004096)
0.3 2.7 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.3 2.3 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.3 0.8 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.3 4.9 GO:0030275 LRR domain binding(GO:0030275)
0.3 1.0 GO:0036033 mediator complex binding(GO:0036033)
0.2 0.7 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.2 3.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.2 1.7 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.2 0.7 GO:0031752 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.2 1.1 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.2 2.4 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.2 6.2 GO:0001223 transcription coactivator binding(GO:0001223)
0.2 1.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.2 0.9 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.2 1.1 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 0.9 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.2 0.6 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.1 1.0 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 1.0 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.7 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 0.4 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.1 0.8 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.7 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.3 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.1 0.4 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.9 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 0.3 GO:0036361 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.1 0.4 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 1.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.3 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.1 0.3 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.1 0.8 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.1 2.0 GO:0008308 voltage-gated anion channel activity(GO:0008308)
0.1 1.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 1.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 1.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 0.3 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 2.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.8 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 0.9 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 0.2 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.1 1.1 GO:0015643 toxic substance binding(GO:0015643)
0.1 1.3 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 0.2 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.1 0.9 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.1 0.3 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.1 2.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 0.8 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 1.0 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 4.5 GO:0030276 clathrin binding(GO:0030276)
0.1 1.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 1.0 GO:0031690 adrenergic receptor binding(GO:0031690)
0.1 0.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.2 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 2.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.8 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.9 GO:0005521 lamin binding(GO:0005521)
0.0 1.0 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.8 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.5 GO:0045499 chemorepellent activity(GO:0045499)
0.0 1.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.3 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.5 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.7 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 1.1 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 1.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.5 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.0 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.5 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.4 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.7 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.6 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.9 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.2 GO:0031005 filamin binding(GO:0031005)
0.0 0.3 GO:0008483 transaminase activity(GO:0008483)
0.0 1.0 GO:0017022 myosin binding(GO:0017022)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.3 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.6 GO:0019213 deacetylase activity(GO:0019213)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 8.6 ST_GA12_PATHWAY G alpha 12 Pathway
0.1 3.0 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 1.3 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.1 2.0 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.1 1.3 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 4.4 PID_SHP2_PATHWAY SHP2 signaling
0.1 3.6 PID_FGF_PATHWAY FGF signaling pathway
0.1 0.7 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.1 2.4 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.2 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 1.6 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 2.3 PID_TNF_PATHWAY TNF receptor signaling pathway
0.0 2.1 PID_FOXO_PATHWAY FoxO family signaling
0.0 1.2 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.9 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.3 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.5 PID_INSULIN_PATHWAY Insulin Pathway
0.0 0.8 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.8 PID_ATR_PATHWAY ATR signaling pathway
0.0 0.2 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.0 0.5 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.4 PID_ERBB1_DOWNSTREAM_PATHWAY ErbB1 downstream signaling
0.0 2.3 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.7 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 0.2 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 1.9 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 8.9 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.3 3.6 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.2 4.0 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 1.9 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.1 3.5 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 0.9 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.1 4.3 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.6 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 5.7 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 2.4 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.2 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 2.3 REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.1 3.3 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 0.8 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 2.1 REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.1 0.8 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 2.0 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 0.8 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.2 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.2 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.6 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.8 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.6 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 1.0 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.0 REACTOME_KINESINS Genes involved in Kinesins
0.0 0.5 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.7 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.9 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 2.8 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.7 REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.3 REACTOME_CTLA4_INHIBITORY_SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.9 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.6 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.5 REACTOME_TRIGLYCERIDE_BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 0.5 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.1 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.4 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.4 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.4 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.0 0.5 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors