Motif ID: Nr4a2

Z-value: 0.489


Transcription factors associated with Nr4a2:

Gene SymbolEntrez IDGene Name
Nr4a2 ENSMUSG00000026826.7 Nr4a2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr4a2mm10_v2_chr2_-_57124003_571240710.444.2e-03Click!


Activity profile for motif Nr4a2.

activity profile for motif Nr4a2


Sorted Z-values histogram for motif Nr4a2

Sorted Z-values for motif Nr4a2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr4a2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_26229707 6.381 ENSMUST00000060716.5
ENSMUST00000164660.1
Samd3

sterile alpha motif domain containing 3

chr18_+_86711059 3.939 ENSMUST00000068423.3
Cbln2
cerebellin 2 precursor protein
chr9_-_32344237 2.278 ENSMUST00000034533.5
Kcnj5
potassium inwardly-rectifying channel, subfamily J, member 5
chr13_+_94875600 1.744 ENSMUST00000022195.10
Otp
orthopedia homolog (Drosophila)
chr2_-_129699833 1.667 ENSMUST00000028883.5
Pdyn
prodynorphin
chr2_+_121295437 1.578 ENSMUST00000110639.1
Map1a
microtubule-associated protein 1 A
chr9_-_106656081 1.366 ENSMUST00000023959.7
Grm2
glutamate receptor, metabotropic 2
chr2_+_4976113 1.122 ENSMUST00000167607.1
ENSMUST00000115010.2
Ucma

upper zone of growth plate and cartilage matrix associated

chr7_-_100514800 1.112 ENSMUST00000054923.7
Dnajb13
DnaJ (Hsp40) related, subfamily B, member 13
chr17_+_29360923 0.962 ENSMUST00000024810.6
Fgd2
FYVE, RhoGEF and PH domain containing 2
chr4_-_36136463 0.945 ENSMUST00000098151.2
Lingo2
leucine rich repeat and Ig domain containing 2
chr13_+_93304066 0.854 ENSMUST00000109493.1
Homer1
homer homolog 1 (Drosophila)
chr8_+_68880491 0.809 ENSMUST00000015712.8
Lpl
lipoprotein lipase
chr8_+_70863127 0.781 ENSMUST00000050921.2
A230052G05Rik
RIKEN cDNA A230052G05 gene
chr6_-_124814288 0.779 ENSMUST00000172132.2
Tpi1
triosephosphate isomerase 1
chrX_+_150589907 0.763 ENSMUST00000080884.4
Pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr18_-_56975333 0.719 ENSMUST00000139243.2
ENSMUST00000025488.8
C330018D20Rik

RIKEN cDNA C330018D20 gene

chrX_-_142390334 0.706 ENSMUST00000112907.1
Acsl4
acyl-CoA synthetase long-chain family member 4
chr1_+_57845534 0.690 ENSMUST00000169772.1
Spats2l
spermatogenesis associated, serine-rich 2-like
chr2_+_61593077 0.662 ENSMUST00000112495.1
ENSMUST00000112501.2
Tank

TRAF family member-associated Nf-kappa B activator

chr2_+_75832168 0.661 ENSMUST00000047232.7
ENSMUST00000111952.2
Agps

alkylglycerone phosphate synthase

chr8_-_119840522 0.617 ENSMUST00000168698.1
ENSMUST00000034285.6
Cotl1

coactosin-like 1 (Dictyostelium)

chr11_-_100822525 0.616 ENSMUST00000107358.2
Stat5b
signal transducer and activator of transcription 5B
chr5_-_121527186 0.565 ENSMUST00000152270.1
Mapkapk5
MAP kinase-activated protein kinase 5
chr8_-_46211284 0.558 ENSMUST00000034049.4
Slc25a4
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4
chr15_-_42676967 0.551 ENSMUST00000022921.5
Angpt1
angiopoietin 1
chr10_-_117224480 0.532 ENSMUST00000020382.6
Yeats4
YEATS domain containing 4
chr8_-_13494479 0.529 ENSMUST00000033828.5
Gas6
growth arrest specific 6
chr5_+_111581422 0.512 ENSMUST00000064930.3
C130026L21Rik
RIKEN cDNA C130026L21 gene
chr11_+_70657687 0.508 ENSMUST00000134087.1
ENSMUST00000170716.1
Eno3

enolase 3, beta muscle

chr9_-_22002599 0.488 ENSMUST00000115336.2
ENSMUST00000044926.5
Ccdc151

coiled-coil domain containing 151

chr1_+_131910458 0.487 ENSMUST00000062264.6
Nucks1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr10_+_110920170 0.468 ENSMUST00000020403.5
Csrp2
cysteine and glycine-rich protein 2
chr11_+_70657196 0.449 ENSMUST00000157027.1
ENSMUST00000072841.5
ENSMUST00000108548.1
ENSMUST00000126241.1
Eno3



enolase 3, beta muscle



chrX_-_48513518 0.437 ENSMUST00000114945.2
ENSMUST00000037349.7
Aifm1

apoptosis-inducing factor, mitochondrion-associated 1

chr9_+_108392820 0.436 ENSMUST00000035234.4
1700102P08Rik
RIKEN cDNA 1700102P08 gene
chr5_+_63649335 0.432 ENSMUST00000159584.1
3110047P20Rik
RIKEN cDNA 3110047P20 gene
chr5_-_31202215 0.427 ENSMUST00000176245.1
ENSMUST00000177310.1
ENSMUST00000114590.1
Zfp513


zinc finger protein 513


chr2_-_101621033 0.426 ENSMUST00000090513.4
B230118H07Rik
RIKEN cDNA B230118H07 gene
chr2_-_73911323 0.417 ENSMUST00000111996.1
ENSMUST00000018914.2
Atp5g3

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)

chr10_+_90829780 0.400 ENSMUST00000179337.2
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr11_-_109722214 0.398 ENSMUST00000020938.7
Fam20a
family with sequence similarity 20, member A
chr10_+_94147982 0.386 ENSMUST00000105290.2
Nr2c1
nuclear receptor subfamily 2, group C, member 1
chr10_+_90829835 0.386 ENSMUST00000179964.1
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr10_+_93589413 0.380 ENSMUST00000181835.1
4933408J17Rik
RIKEN cDNA 4933408J17 gene
chr1_-_124045247 0.379 ENSMUST00000112603.2
Dpp10
dipeptidylpeptidase 10
chr3_+_4211716 0.379 ENSMUST00000170943.1
Gm8775
predicted gene 8775
chr2_-_73892619 0.345 ENSMUST00000112007.1
ENSMUST00000112016.2
Atf2

activating transcription factor 2

chr18_-_15063560 0.318 ENSMUST00000168989.1
Kctd1
potassium channel tetramerisation domain containing 1
chr18_+_36664060 0.310 ENSMUST00000036765.7
Eif4ebp3
eukaryotic translation initiation factor 4E binding protein 3
chr10_-_93589621 0.297 ENSMUST00000020203.6
Snrpf
small nuclear ribonucleoprotein polypeptide F
chr10_-_99759658 0.294 ENSMUST00000056085.4
Csl
citrate synthase like
chr3_+_14578609 0.292 ENSMUST00000029069.6
ENSMUST00000165922.2
E2f5

E2F transcription factor 5

chr5_-_137613759 0.285 ENSMUST00000155251.1
ENSMUST00000124693.1
Pcolce

procollagen C-endopeptidase enhancer protein

chr11_-_70656467 0.281 ENSMUST00000131642.1
Gm12319
predicted gene 12319
chr1_+_167618246 0.276 ENSMUST00000111380.1
Rxrg
retinoid X receptor gamma
chr9_+_118506226 0.256 ENSMUST00000084820.4
Golga4
golgi autoantigen, golgin subfamily a, 4
chr2_-_73892588 0.252 ENSMUST00000154456.1
ENSMUST00000090802.4
ENSMUST00000055833.5
Atf2


activating transcription factor 2


chr7_-_141429433 0.245 ENSMUST00000124444.1
Cend1
cell cycle exit and neuronal differentiation 1
chr8_-_64733534 0.238 ENSMUST00000141021.1
Sc4mol
sterol-C4-methyl oxidase-like
chrX_-_73921917 0.234 ENSMUST00000114389.3
Naa10
N(alpha)-acetyltransferase 10, NatA catalytic subunit
chr3_+_84925476 0.233 ENSMUST00000107675.1
Fbxw7
F-box and WD-40 domain protein 7
chr4_+_102760135 0.226 ENSMUST00000066824.7
Sgip1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr9_+_95637601 0.211 ENSMUST00000015498.8
Pcolce2
procollagen C-endopeptidase enhancer 2
chr2_+_61593125 0.204 ENSMUST00000112494.1
Tank
TRAF family member-associated Nf-kappa B activator
chrX_-_73921930 0.204 ENSMUST00000033763.8
Naa10
N(alpha)-acetyltransferase 10, NatA catalytic subunit
chrX_+_7579666 0.203 ENSMUST00000115740.1
ENSMUST00000115739.1
Foxp3

forkhead box P3

chr4_-_141623799 0.200 ENSMUST00000038661.7
Slc25a34
solute carrier family 25, member 34
chr1_-_87573825 0.191 ENSMUST00000068681.5
Ngef
neuronal guanine nucleotide exchange factor
chr15_-_89425856 0.185 ENSMUST00000109313.2
Cpt1b
carnitine palmitoyltransferase 1b, muscle
chr10_-_40302186 0.181 ENSMUST00000099945.4
Amd1
S-adenosylmethionine decarboxylase 1
chr1_+_137966529 0.169 ENSMUST00000182158.1
A430106G13Rik
RIKEN cDNA A430106G13 gene
chr14_-_30915387 0.168 ENSMUST00000166622.1
Itih3
inter-alpha trypsin inhibitor, heavy chain 3
chr9_-_64737684 0.159 ENSMUST00000171100.1
ENSMUST00000167569.1
ENSMUST00000004892.6
ENSMUST00000172298.1
Rab11a



RAB11a, member RAS oncogene family



chr1_-_63176653 0.155 ENSMUST00000027111.8
ENSMUST00000168099.2
Ndufs1

NADH dehydrogenase (ubiquinone) Fe-S protein 1

chrX_-_73921828 0.154 ENSMUST00000096316.3
ENSMUST00000114390.1
ENSMUST00000114391.3
ENSMUST00000114387.1
Naa10



N(alpha)-acetyltransferase 10, NatA catalytic subunit



chr13_+_93303757 0.141 ENSMUST00000109494.1
Homer1
homer homolog 1 (Drosophila)
chr4_+_102760294 0.141 ENSMUST00000072481.5
ENSMUST00000156596.1
ENSMUST00000080728.6
ENSMUST00000106882.2
Sgip1



SH3-domain GRB2-like (endophilin) interacting protein 1



chr9_-_64737623 0.136 ENSMUST00000169058.1
Rab11a
RAB11a, member RAS oncogene family
chr17_-_35910032 0.131 ENSMUST00000141662.1
ENSMUST00000056034.6
ENSMUST00000077494.6
ENSMUST00000149277.1
ENSMUST00000061052.5
Atat1




alpha tubulin acetyltransferase 1




chr7_-_141429351 0.129 ENSMUST00000164387.1
ENSMUST00000137488.1
ENSMUST00000084436.3
Cend1


cell cycle exit and neuronal differentiation 1


chr19_-_6921753 0.127 ENSMUST00000173635.1
Esrra
estrogen related receptor, alpha
chr2_-_59160644 0.127 ENSMUST00000077687.5
Ccdc148
coiled-coil domain containing 148
chr5_+_135187251 0.127 ENSMUST00000002825.5
Baz1b
bromodomain adjacent to zinc finger domain, 1B
chr16_-_44139196 0.126 ENSMUST00000063661.6
ENSMUST00000114666.2
Atp6v1a

ATPase, H+ transporting, lysosomal V1 subunit A

chr2_-_26237368 0.125 ENSMUST00000036187.8
Qsox2
quiescin Q6 sulfhydryl oxidase 2
chr7_+_4690760 0.122 ENSMUST00000048248.7
Brsk1
BR serine/threonine kinase 1
chr2_+_59160838 0.118 ENSMUST00000102754.4
ENSMUST00000168631.1
ENSMUST00000123908.1
Pkp4


plakophilin 4


chr6_-_99096196 0.117 ENSMUST00000175886.1
Foxp1
forkhead box P1
chr10_+_42502197 0.114 ENSMUST00000105499.1
Snx3
sorting nexin 3
chr10_+_53337686 0.113 ENSMUST00000046221.6
ENSMUST00000163319.1
Pln

phospholamban

chr1_+_182409162 0.112 ENSMUST00000117245.1
Trp53bp2
transformation related protein 53 binding protein 2
chr17_+_47737030 0.099 ENSMUST00000086932.3
Tfeb
transcription factor EB
chr5_+_150259922 0.095 ENSMUST00000087204.5
Fry
furry homolog (Drosophila)
chr16_+_8830093 0.095 ENSMUST00000023150.5
1810013L24Rik
RIKEN cDNA 1810013L24 gene
chr7_+_125603420 0.094 ENSMUST00000033000.6
Il21r
interleukin 21 receptor
chr7_+_105554360 0.090 ENSMUST00000046983.8
Smpd1
sphingomyelin phosphodiesterase 1, acid lysosomal
chr16_+_44139821 0.082 ENSMUST00000159514.1
ENSMUST00000161326.1
ENSMUST00000063520.8
ENSMUST00000063542.7
Naa50



N(alpha)-acetyltransferase 50, NatE catalytic subunit



chr1_+_63176818 0.079 ENSMUST00000129339.1
Eef1b2
eukaryotic translation elongation factor 1 beta 2
chr6_+_48613180 0.072 ENSMUST00000061720.4
Zfp775
zinc finger protein 775
chr3_-_95133989 0.070 ENSMUST00000172572.2
ENSMUST00000173462.2
Scnm1

sodium channel modifier 1

chr4_-_42528175 0.063 ENSMUST00000180201.1
Gm13298
predicted gene 13298
chr2_-_165283599 0.061 ENSMUST00000155289.1
Slc35c2
solute carrier family 35, member C2
chr2_-_73892530 0.058 ENSMUST00000136958.1
ENSMUST00000112010.2
ENSMUST00000128531.1
ENSMUST00000112017.1
Atf2



activating transcription factor 2



chr10_-_35711891 0.055 ENSMUST00000080898.2
Amd2
S-adenosylmethionine decarboxylase 2
chr15_-_102516806 0.046 ENSMUST00000169162.1
ENSMUST00000023812.2
ENSMUST00000165174.1
ENSMUST00000169367.1
ENSMUST00000169377.1
Map3k12




mitogen-activated protein kinase kinase kinase 12




chr13_-_17805093 0.039 ENSMUST00000042365.7
Cdk13
cyclin-dependent kinase 13
chr6_+_96113146 0.036 ENSMUST00000122120.1
Fam19a1
family with sequence similarity 19, member A1
chr8_+_117095854 0.034 ENSMUST00000034308.8
ENSMUST00000167370.1
ENSMUST00000176860.1
Bcmo1


beta-carotene 15,15'-monooxygenase


chr15_+_25940846 0.025 ENSMUST00000110438.1
Fam134b
family with sequence similarity 134, member B
chr2_+_132781278 0.021 ENSMUST00000028826.3
Chgb
chromogranin B
chr10_-_42478488 0.010 ENSMUST00000041024.8
Lace1
lactation elevated 1
chr17_-_43667015 0.008 ENSMUST00000024705.4
Slc25a27
solute carrier family 25, member 27
chr1_-_167393826 0.006 ENSMUST00000028005.2
Mgst3
microsomal glutathione S-transferase 3
chr6_+_3993776 0.003 ENSMUST00000031673.5
Gngt1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr7_+_120635176 0.000 ENSMUST00000033176.5
Uqcrc2
ubiquinol cytochrome c reductase core protein 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.3 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.3 0.8 GO:0019405 alditol catabolic process(GO:0019405) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.2 0.7 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.2 0.9 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.2 0.6 GO:0046544 regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819) development of secondary male sexual characteristics(GO:0046544)
0.2 0.8 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.2 0.6 GO:0015866 ADP transport(GO:0015866)
0.2 0.6 GO:0030210 heparin biosynthetic process(GO:0030210) Tie signaling pathway(GO:0048014)
0.2 0.5 GO:0003104 positive regulation of glomerular filtration(GO:0003104) negative regulation of protein import into nucleus, translocation(GO:0033159) regulation of oligodendrocyte apoptotic process(GO:1900141) negative regulation of oligodendrocyte apoptotic process(GO:1900142) positive regulation of dendritic cell chemotaxis(GO:2000510)
0.2 0.5 GO:0019046 release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382)
0.1 0.4 GO:0021933 radial glia guided migration of cerebellar granule cell(GO:0021933)
0.1 1.7 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.1 0.6 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.1 0.8 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.2 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.3 GO:0010796 regulation of multivesicular body size(GO:0010796)
0.1 0.6 GO:0090400 stress-induced premature senescence(GO:0090400)
0.1 0.7 GO:0032306 regulation of prostaglandin secretion(GO:0032306)
0.1 0.2 GO:0032829 positive regulation of T cell anergy(GO:0002669) negative regulation of T cell cytokine production(GO:0002725) positive regulation of lymphocyte anergy(GO:0002913) regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of immature T cell proliferation in thymus(GO:0033092) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 1.0 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.1 0.8 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 0.4 GO:1902510 regulation of apoptotic DNA fragmentation(GO:1902510)
0.0 0.1 GO:0009814 defense response, incompatible interaction(GO:0009814)
0.0 4.9 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.2 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.0 0.4 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.5 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 1.6 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.4 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.1 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.0 1.4 GO:0014047 glutamate secretion(GO:0014047)
0.0 1.7 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.1 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.0 0.6 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.2 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 1.1 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 1.1 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.3 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.1 GO:0015786 UDP-glucose transport(GO:0015786)
0.0 0.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0061470 interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0086023 adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.0 1.0 GO:0006096 glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757)
0.0 0.1 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.1 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 1.0 GO:0043507 positive regulation of JUN kinase activity(GO:0043507)
0.0 0.3 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.1 0.8 GO:0042627 chylomicron(GO:0042627)
0.1 1.0 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.7 GO:0031415 NatA complex(GO:0031415)
0.1 0.7 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 0.3 GO:0034715 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
0.1 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.6 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 2.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.4 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 1.1 GO:0016235 aggresome(GO:0016235)
0.0 1.0 GO:0043034 costamere(GO:0043034)
0.0 0.5 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 1.4 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.7 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.6 GO:0005930 axoneme(GO:0005930)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 1.6 GO:0005875 microtubule associated complex(GO:0005875)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.1 GO:0042599 lamellar body(GO:0042599)
0.0 1.7 GO:0043679 axon terminus(GO:0043679)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.3 1.4 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.2 0.9 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.2 1.3 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.4 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.6 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.1 0.8 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 1.0 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.0 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.1 0.8 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 0.8 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.7 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.7 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.2 GO:0019808 polyamine binding(GO:0019808)
0.1 0.6 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.5 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.6 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 2.1 GO:0005518 collagen binding(GO:0005518)
0.0 0.3 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 1.0 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.3 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 1.1 GO:0051082 unfolded protein binding(GO:0051082)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.6 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 1.2 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.3 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 0.6 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.5 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.0 0.2 PID_MYC_PATHWAY C-MYC pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.1 1.4 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 2.3 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 2.5 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 0.8 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 0.6 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.9 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.7 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.7 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.3 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.6 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.7 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.3 REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.6 REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 1.0 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.3 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1