Motif ID: Nfe2l1_Mafg
Z-value: 1.127


Transcription factors associated with Nfe2l1_Mafg:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Mafg | ENSMUSG00000051510.7 | Mafg |
Mafg | ENSMUSG00000053906.4 | Mafg |
Nfe2l1 | ENSMUSG00000038615.11 | Nfe2l1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Mafg | mm10_v2_chr11_-_120633594_120633605 | -0.65 | 3.9e-06 | Click! |
Nfe2l1 | mm10_v2_chr11_-_96829904_96829955 | -0.16 | 3.2e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
5.3 | 32.0 | GO:0021797 | forebrain anterior/posterior pattern specification(GO:0021797) |
2.6 | 7.8 | GO:0071649 | negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865) regulation of chemokine (C-C motif) ligand 5 production(GO:0071649) positive regulation of somatostatin secretion(GO:0090274) |
1.5 | 4.5 | GO:1902310 | positive regulation of peptidyl-serine dephosphorylation(GO:1902310) |
1.0 | 3.1 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
1.0 | 4.1 | GO:0010511 | regulation of phosphatidylinositol biosynthetic process(GO:0010511) |
0.8 | 4.0 | GO:0007197 | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207) |
0.7 | 3.6 | GO:0060467 | negative regulation of fertilization(GO:0060467) |
0.6 | 3.7 | GO:0072318 | clathrin coat disassembly(GO:0072318) |
0.5 | 2.4 | GO:0097476 | spinal cord motor neuron migration(GO:0097476) |
0.5 | 1.4 | GO:1900133 | renin secretion into blood stream(GO:0002001) regulation of renin secretion into blood stream(GO:1900133) |
0.4 | 1.2 | GO:0070649 | formin-nucleated actin cable assembly(GO:0070649) |
0.4 | 1.2 | GO:0010845 | positive regulation of reciprocal meiotic recombination(GO:0010845) |
0.4 | 4.3 | GO:0048934 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
0.4 | 2.8 | GO:2000124 | regulation of endocannabinoid signaling pathway(GO:2000124) |
0.3 | 4.3 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
0.3 | 2.3 | GO:0016560 | protein import into peroxisome matrix, docking(GO:0016560) |
0.3 | 4.6 | GO:2000042 | negative regulation of double-strand break repair via homologous recombination(GO:2000042) |
0.3 | 5.7 | GO:0031987 | locomotion involved in locomotory behavior(GO:0031987) |
0.3 | 2.0 | GO:1901029 | negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029) |
0.3 | 0.8 | GO:0032918 | polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918) |
0.3 | 0.8 | GO:1903538 | meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538) |
0.3 | 2.0 | GO:0038031 | non-canonical Wnt signaling pathway via JNK cascade(GO:0038031) |
0.2 | 1.0 | GO:0060830 | ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) |
0.2 | 2.2 | GO:0098700 | neurotransmitter loading into synaptic vesicle(GO:0098700) |
0.2 | 0.7 | GO:0034140 | negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) aggrephagy(GO:0035973) |
0.2 | 0.9 | GO:1901492 | positive regulation of lymphangiogenesis(GO:1901492) |
0.2 | 1.2 | GO:0090164 | asymmetric Golgi ribbon formation(GO:0090164) |
0.2 | 0.7 | GO:0060399 | positive regulation of growth hormone receptor signaling pathway(GO:0060399) |
0.2 | 0.7 | GO:0019085 | early viral transcription(GO:0019085) |
0.2 | 1.1 | GO:0018171 | peptidyl-cysteine oxidation(GO:0018171) |
0.2 | 3.0 | GO:0007220 | Notch receptor processing(GO:0007220) |
0.2 | 1.8 | GO:0031424 | keratinization(GO:0031424) |
0.2 | 2.1 | GO:0060539 | diaphragm development(GO:0060539) |
0.2 | 1.2 | GO:0021780 | oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780) |
0.2 | 0.6 | GO:0002188 | translation reinitiation(GO:0002188) |
0.1 | 0.7 | GO:0042364 | water-soluble vitamin biosynthetic process(GO:0042364) |
0.1 | 0.6 | GO:0015786 | UDP-glucose transport(GO:0015786) |
0.1 | 0.4 | GO:0021759 | globus pallidus development(GO:0021759) |
0.1 | 0.4 | GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
0.1 | 0.4 | GO:0036228 | protein targeting to nuclear inner membrane(GO:0036228) |
0.1 | 0.6 | GO:0010735 | positive regulation of transcription via serum response element binding(GO:0010735) |
0.1 | 2.9 | GO:2001224 | positive regulation of neuron migration(GO:2001224) |
0.1 | 0.5 | GO:2000182 | regulation of progesterone biosynthetic process(GO:2000182) |
0.1 | 1.1 | GO:0061470 | interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619) |
0.1 | 0.5 | GO:0045578 | negative regulation of B cell differentiation(GO:0045578) |
0.1 | 1.2 | GO:0072600 | establishment of protein localization to Golgi(GO:0072600) |
0.1 | 0.3 | GO:1904139 | microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) |
0.1 | 1.7 | GO:0031340 | positive regulation of vesicle fusion(GO:0031340) |
0.1 | 1.3 | GO:0060013 | righting reflex(GO:0060013) |
0.1 | 6.2 | GO:0070936 | protein K48-linked ubiquitination(GO:0070936) |
0.1 | 0.3 | GO:0002842 | positive regulation of T cell mediated immune response to tumor cell(GO:0002842) protein import into mitochondrial intermembrane space(GO:0045041) |
0.1 | 0.7 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
0.1 | 1.8 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
0.1 | 1.3 | GO:1902004 | positive regulation of beta-amyloid formation(GO:1902004) |
0.1 | 0.5 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
0.1 | 0.4 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
0.1 | 0.2 | GO:0032474 | otolith morphogenesis(GO:0032474) |
0.1 | 0.3 | GO:1903984 | regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984) |
0.1 | 0.4 | GO:0031120 | snRNA pseudouridine synthesis(GO:0031120) |
0.1 | 0.3 | GO:1903756 | regulation of postsynaptic density protein 95 clustering(GO:1902897) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758) |
0.1 | 1.7 | GO:0000154 | rRNA modification(GO:0000154) |
0.1 | 0.6 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
0.1 | 0.5 | GO:0034143 | regulation of toll-like receptor 4 signaling pathway(GO:0034143) |
0.1 | 0.5 | GO:0019673 | GDP-mannose metabolic process(GO:0019673) |
0.1 | 0.5 | GO:2000786 | positive regulation of autophagosome assembly(GO:2000786) |
0.1 | 0.2 | GO:0009106 | lipoate metabolic process(GO:0009106) |
0.0 | 0.7 | GO:1903504 | regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504) |
0.0 | 0.6 | GO:0045899 | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899) |
0.0 | 0.3 | GO:0051189 | molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189) |
0.0 | 0.2 | GO:0000480 | endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480) |
0.0 | 0.9 | GO:0006625 | protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663) |
0.0 | 0.1 | GO:0030210 | heparin biosynthetic process(GO:0030210) Tie signaling pathway(GO:0048014) |
0.0 | 0.6 | GO:1904321 | response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322) |
0.0 | 0.4 | GO:2000074 | regulation of type B pancreatic cell development(GO:2000074) |
0.0 | 0.3 | GO:0060339 | negative regulation of type I interferon-mediated signaling pathway(GO:0060339) |
0.0 | 2.2 | GO:1901998 | toxin transport(GO:1901998) |
0.0 | 0.5 | GO:0031468 | nuclear envelope reassembly(GO:0031468) |
0.0 | 0.2 | GO:1904659 | glucose transmembrane transport(GO:1904659) |
0.0 | 0.5 | GO:0071300 | cellular response to retinoic acid(GO:0071300) |
0.0 | 0.4 | GO:0043615 | astrocyte cell migration(GO:0043615) |
0.0 | 1.0 | GO:0018105 | peptidyl-serine phosphorylation(GO:0018105) |
0.0 | 0.2 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
0.0 | 0.2 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
0.0 | 0.3 | GO:0045876 | positive regulation of sister chromatid cohesion(GO:0045876) |
0.0 | 1.0 | GO:0070207 | protein homotrimerization(GO:0070207) |
0.0 | 0.3 | GO:0006020 | inositol metabolic process(GO:0006020) |
0.0 | 2.6 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
0.0 | 0.4 | GO:0051123 | RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) |
0.0 | 0.2 | GO:1900194 | negative regulation of oocyte maturation(GO:1900194) |
0.0 | 1.4 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
0.0 | 0.4 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
0.0 | 1.0 | GO:0006367 | transcription initiation from RNA polymerase II promoter(GO:0006367) |
0.0 | 0.5 | GO:0007030 | Golgi organization(GO:0007030) |
0.0 | 0.2 | GO:0032049 | cardiolipin biosynthetic process(GO:0032049) |
0.0 | 0.7 | GO:0090022 | regulation of neutrophil chemotaxis(GO:0090022) |
0.0 | 0.5 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
0.0 | 1.3 | GO:0002181 | cytoplasmic translation(GO:0002181) |
0.0 | 0.9 | GO:0042773 | ATP synthesis coupled electron transport(GO:0042773) |
0.0 | 0.5 | GO:0034453 | microtubule anchoring(GO:0034453) |
0.0 | 1.1 | GO:0051865 | protein autoubiquitination(GO:0051865) |
0.0 | 0.7 | GO:0000186 | activation of MAPKK activity(GO:0000186) |
0.0 | 0.1 | GO:1904245 | regulation of polynucleotide adenylyltransferase activity(GO:1904245) |
0.0 | 0.3 | GO:0045292 | mRNA cis splicing, via spliceosome(GO:0045292) |
0.0 | 0.4 | GO:2001222 | regulation of neuron migration(GO:2001222) |
0.0 | 0.3 | GO:0022904 | respiratory electron transport chain(GO:0022904) |
0.0 | 2.0 | GO:0006261 | DNA-dependent DNA replication(GO:0006261) |
0.0 | 1.7 | GO:0000086 | G2/M transition of mitotic cell cycle(GO:0000086) |
0.0 | 0.3 | GO:0071625 | vocalization behavior(GO:0071625) |
0.0 | 0.7 | GO:0061077 | chaperone-mediated protein folding(GO:0061077) |
0.0 | 0.7 | GO:0043066 | negative regulation of apoptotic process(GO:0043066) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 2.3 | GO:0017071 | intracellular cyclic nucleotide activated cation channel complex(GO:0017071) |
0.5 | 2.0 | GO:0008623 | CHRAC(GO:0008623) |
0.4 | 3.0 | GO:0070765 | gamma-secretase complex(GO:0070765) |
0.4 | 1.8 | GO:0001533 | cornified envelope(GO:0001533) |
0.3 | 4.1 | GO:0070852 | cell body fiber(GO:0070852) |
0.2 | 1.7 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
0.2 | 0.7 | GO:0035061 | interchromatin granule(GO:0035061) |
0.2 | 2.8 | GO:0043196 | varicosity(GO:0043196) |
0.2 | 1.2 | GO:0033503 | HULC complex(GO:0033503) |
0.2 | 0.5 | GO:1990730 | VCP-NSFL1C complex(GO:1990730) |
0.2 | 5.6 | GO:0035861 | site of double-strand break(GO:0035861) |
0.2 | 1.9 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
0.2 | 0.9 | GO:0071817 | MMXD complex(GO:0071817) |
0.1 | 1.4 | GO:0012505 | endomembrane system(GO:0012505) |
0.1 | 1.5 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
0.1 | 1.0 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
0.1 | 2.3 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
0.1 | 0.4 | GO:0090661 | box H/ACA telomerase RNP complex(GO:0090661) |
0.1 | 0.3 | GO:0042025 | host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094) |
0.1 | 0.3 | GO:0043197 | dendritic spine(GO:0043197) neuron spine(GO:0044309) |
0.1 | 0.4 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
0.1 | 1.1 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
0.1 | 0.6 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
0.1 | 0.7 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
0.1 | 1.4 | GO:0033276 | transcription factor TFTC complex(GO:0033276) |
0.1 | 0.7 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
0.1 | 0.6 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
0.1 | 0.7 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
0.1 | 7.0 | GO:0043195 | terminal bouton(GO:0043195) |
0.1 | 0.4 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
0.1 | 0.7 | GO:0036513 | Derlin-1 retrotranslocation complex(GO:0036513) |
0.0 | 0.5 | GO:0044233 | ER-mitochondrion membrane contact site(GO:0044233) |
0.0 | 0.8 | GO:0016460 | myosin II complex(GO:0016460) |
0.0 | 0.4 | GO:0005642 | annulate lamellae(GO:0005642) |
0.0 | 0.5 | GO:0090543 | Flemming body(GO:0090543) |
0.0 | 3.0 | GO:0009925 | basal plasma membrane(GO:0009925) |
0.0 | 1.8 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
0.0 | 0.3 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
0.0 | 0.7 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
0.0 | 1.0 | GO:0008305 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
0.0 | 0.8 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
0.0 | 1.0 | GO:0071565 | nBAF complex(GO:0071565) |
0.0 | 3.1 | GO:0001669 | acrosomal vesicle(GO:0001669) |
0.0 | 0.2 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
0.0 | 0.8 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
0.0 | 1.1 | GO:0043034 | costamere(GO:0043034) |
0.0 | 0.3 | GO:0042382 | paraspeckles(GO:0042382) |
0.0 | 0.2 | GO:0005964 | phosphorylase kinase complex(GO:0005964) |
0.0 | 0.6 | GO:0005686 | U2 snRNP(GO:0005686) |
0.0 | 0.4 | GO:0031011 | Ino80 complex(GO:0031011) |
0.0 | 0.3 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
0.0 | 0.8 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
0.0 | 0.3 | GO:0043198 | dendritic shaft(GO:0043198) |
0.0 | 1.3 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
0.0 | 0.9 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
0.0 | 2.8 | GO:0001650 | fibrillar center(GO:0001650) |
0.0 | 0.7 | GO:0016235 | aggresome(GO:0016235) |
0.0 | 1.2 | GO:0031985 | Golgi cisterna(GO:0031985) |
0.0 | 0.4 | GO:0005669 | transcription factor TFIID complex(GO:0005669) |
0.0 | 0.2 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
0.0 | 0.6 | GO:0005801 | cis-Golgi network(GO:0005801) |
0.0 | 2.1 | GO:0070062 | extracellular exosome(GO:0070062) |
0.0 | 0.9 | GO:0005811 | lipid particle(GO:0005811) |
0.0 | 0.2 | GO:0031083 | BLOC-1 complex(GO:0031083) |
0.0 | 0.5 | GO:0097440 | apical dendrite(GO:0097440) |
0.0 | 0.2 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
0.0 | 0.7 | GO:0030863 | cortical cytoskeleton(GO:0030863) |
0.0 | 5.1 | GO:0005730 | nucleolus(GO:0005730) |
0.0 | 0.4 | GO:0032420 | stereocilium(GO:0032420) |
0.0 | 0.5 | GO:0044295 | axonal growth cone(GO:0044295) |
0.0 | 1.7 | GO:0030426 | growth cone(GO:0030426) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.5 | 4.5 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
1.4 | 4.1 | GO:0004993 | G-protein coupled serotonin receptor activity(GO:0004993) |
1.3 | 4.0 | GO:0016934 | extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934) |
1.0 | 5.7 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
0.9 | 5.6 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
0.8 | 3.1 | GO:0004126 | cytidine deaminase activity(GO:0004126) |
0.6 | 4.3 | GO:0015198 | oligopeptide transporter activity(GO:0015198) |
0.5 | 7.8 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
0.5 | 1.4 | GO:0051379 | epinephrine binding(GO:0051379) |
0.5 | 2.3 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
0.4 | 1.7 | GO:0031800 | type 3 metabotropic glutamate receptor binding(GO:0031800) |
0.3 | 2.1 | GO:0015197 | peptide transporter activity(GO:0015197) |
0.3 | 0.8 | GO:0004145 | diamine N-acetyltransferase activity(GO:0004145) |
0.2 | 2.0 | GO:0034711 | inhibin binding(GO:0034711) |
0.2 | 2.4 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
0.2 | 2.8 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
0.2 | 2.9 | GO:0070742 | C2H2 zinc finger domain binding(GO:0070742) |
0.2 | 1.0 | GO:0098634 | protein binding involved in cell-matrix adhesion(GO:0098634) |
0.2 | 34.8 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
0.2 | 0.5 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
0.1 | 2.9 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.1 | 6.7 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
0.1 | 1.2 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.1 | 0.6 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
0.1 | 0.5 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
0.1 | 2.2 | GO:0005313 | L-glutamate transmembrane transporter activity(GO:0005313) |
0.1 | 1.7 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
0.1 | 0.6 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
0.1 | 1.1 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
0.1 | 0.7 | GO:0031419 | cobalamin binding(GO:0031419) |
0.1 | 1.0 | GO:0017162 | aryl hydrocarbon receptor binding(GO:0017162) |
0.1 | 0.5 | GO:0032767 | copper-dependent protein binding(GO:0032767) |
0.1 | 0.9 | GO:0015217 | ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217) |
0.1 | 2.0 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.1 | 0.7 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
0.1 | 0.7 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
0.1 | 3.6 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.1 | 2.4 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
0.1 | 1.1 | GO:0005172 | vascular endothelial growth factor receptor binding(GO:0005172) |
0.1 | 1.5 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.1 | 0.4 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
0.1 | 0.6 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
0.1 | 0.5 | GO:0003993 | acid phosphatase activity(GO:0003993) |
0.1 | 0.7 | GO:0019215 | intermediate filament binding(GO:0019215) |
0.1 | 0.2 | GO:0016979 | lipoate-protein ligase activity(GO:0016979) |
0.1 | 0.6 | GO:0004016 | adenylate cyclase activity(GO:0004016) |
0.0 | 0.3 | GO:0008440 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) |
0.0 | 0.2 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
0.0 | 0.4 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) |
0.0 | 5.6 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
0.0 | 0.3 | GO:0034186 | apolipoprotein A-I binding(GO:0034186) |
0.0 | 0.7 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
0.0 | 0.3 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
0.0 | 0.5 | GO:0031996 | thioesterase binding(GO:0031996) |
0.0 | 14.4 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) |
0.0 | 0.2 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
0.0 | 1.7 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.0 | 1.0 | GO:0051059 | NF-kappaB binding(GO:0051059) |
0.0 | 0.2 | GO:0004689 | phosphorylase kinase activity(GO:0004689) |
0.0 | 0.5 | GO:0034185 | apolipoprotein binding(GO:0034185) |
0.0 | 0.4 | GO:0017070 | U6 snRNA binding(GO:0017070) |
0.0 | 0.4 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
0.0 | 0.4 | GO:0070628 | proteasome binding(GO:0070628) |
0.0 | 0.3 | GO:0016783 | sulfurtransferase activity(GO:0016783) |
0.0 | 0.5 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
0.0 | 0.8 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
0.0 | 1.3 | GO:0019843 | rRNA binding(GO:0019843) |
0.0 | 0.4 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
0.0 | 1.3 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.0 | 0.5 | GO:0008198 | ferrous iron binding(GO:0008198) |
0.0 | 0.3 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
0.0 | 0.7 | GO:0016876 | aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876) |
0.0 | 0.3 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
0.0 | 0.2 | GO:0005355 | glucose transmembrane transporter activity(GO:0005355) |
0.0 | 0.9 | GO:0003743 | translation initiation factor activity(GO:0003743) |
0.0 | 0.3 | GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980) |
0.0 | 0.9 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
0.0 | 0.7 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
0.0 | 0.3 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.0 | 0.8 | GO:0035254 | glutamate receptor binding(GO:0035254) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 2.9 | PID_SYNDECAN_3_PATHWAY | Syndecan-3-mediated signaling events |
0.1 | 5.1 | PID_TCR_CALCIUM_PATHWAY | Calcium signaling in the CD4+ TCR pathway |
0.1 | 4.3 | PID_P38_MK2_PATHWAY | p38 signaling mediated by MAPKAP kinases |
0.1 | 1.2 | PID_TCR_RAS_PATHWAY | Ras signaling in the CD4+ TCR pathway |
0.1 | 2.5 | PID_NFKAPPAB_CANONICAL_PATHWAY | Canonical NF-kappaB pathway |
0.1 | 0.9 | PID_VEGF_VEGFR_PATHWAY | VEGF and VEGFR signaling network |
0.1 | 2.0 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
0.0 | 0.3 | ST_PAC1_RECEPTOR_PATHWAY | PAC1 Receptor Pathway |
0.0 | 1.4 | ST_MYOCYTE_AD_PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
0.0 | 2.2 | PID_BCR_5PATHWAY | BCR signaling pathway |
0.0 | 0.6 | PID_LPA4_PATHWAY | LPA4-mediated signaling events |
0.0 | 0.8 | PID_INTEGRIN_A9B1_PATHWAY | Alpha9 beta1 integrin signaling events |
0.0 | 0.7 | PID_P38_MKK3_6PATHWAY | p38 MAPK signaling pathway |
0.0 | 0.5 | PID_SYNDECAN_2_PATHWAY | Syndecan-2-mediated signaling events |
0.0 | 1.1 | SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES | Genes related to regulation of the actin cytoskeleton |
0.0 | 0.7 | PID_ANGIOPOIETIN_RECEPTOR_PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
0.0 | 0.5 | PID_ARF6_DOWNSTREAM_PATHWAY | Arf6 downstream pathway |
0.0 | 0.7 | PID_ATF2_PATHWAY | ATF-2 transcription factor network |
0.0 | 1.8 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.0 | 0.3 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
0.0 | 0.7 | PID_CXCR4_PATHWAY | CXCR4-mediated signaling events |
0.0 | 0.4 | PID_HNF3B_PATHWAY | FOXA2 and FOXA3 transcription factor networks |
0.0 | 1.1 | PID_MYC_ACTIV_PATHWAY | Validated targets of C-MYC transcriptional activation |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.4 | 4.1 | REACTOME_SEROTONIN_RECEPTORS | Genes involved in Serotonin receptors |
0.5 | 4.3 | REACTOME_TRANSPORT_OF_ORGANIC_ANIONS | Genes involved in Transport of organic anions |
0.5 | 4.9 | REACTOME_AMINE_LIGAND_BINDING_RECEPTORS | Genes involved in Amine ligand-binding receptors |
0.2 | 2.9 | REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR | Genes involved in Regulated proteolysis of p75NTR |
0.2 | 7.8 | REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS | Genes involved in Glucagon-type ligand receptors |
0.1 | 2.8 | REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
0.1 | 2.5 | REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
0.1 | 3.7 | REACTOME_LYSOSOME_VESICLE_BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
0.1 | 2.2 | REACTOME_TIE2_SIGNALING | Genes involved in Tie2 Signaling |
0.1 | 1.9 | REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
0.1 | 0.9 | REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
0.1 | 2.6 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
0.1 | 1.8 | REACTOME_OTHER_SEMAPHORIN_INTERACTIONS | Genes involved in Other semaphorin interactions |
0.1 | 0.3 | REACTOME_ADP_SIGNALLING_THROUGH_P2RY12 | Genes involved in ADP signalling through P2Y purinoceptor 12 |
0.1 | 0.8 | REACTOME_METABOLISM_OF_POLYAMINES | Genes involved in Metabolism of polyamines |
0.1 | 2.0 | REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
0.1 | 0.6 | REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY | Genes involved in Adenylate cyclase inhibitory pathway |
0.0 | 0.5 | REACTOME_CALNEXIN_CALRETICULIN_CYCLE | Genes involved in Calnexin/calreticulin cycle |
0.0 | 1.3 | REACTOME_MRNA_SPLICING_MINOR_PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
0.0 | 2.2 | REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |
0.0 | 3.1 | REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
0.0 | 2.1 | REACTOME_RNA_POL_II_PRE_TRANSCRIPTION_EVENTS | Genes involved in RNA Polymerase II Pre-transcription Events |
0.0 | 1.7 | REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G | Genes involved in Vif-mediated degradation of APOBEC3G |
0.0 | 0.7 | REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
0.0 | 0.4 | REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
0.0 | 1.1 | REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS | Genes involved in Interactions of Vpr with host cellular proteins |
0.0 | 0.2 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PG | Genes involved in Acyl chain remodelling of PG |
0.0 | 0.5 | REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
0.0 | 0.5 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
0.0 | 0.4 | REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
0.0 | 0.6 | REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
0.0 | 2.8 | REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
0.0 | 0.6 | REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING | Genes involved in Sema4D in semaphorin signaling |
0.0 | 0.2 | REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
0.0 | 1.7 | REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE | Genes involved in SRP-dependent cotranslational protein targeting to membrane |
0.0 | 0.9 | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT | Genes involved in Respiratory electron transport |
0.0 | 0.9 | REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
0.0 | 0.4 | REACTOME_EXTENSION_OF_TELOMERES | Genes involved in Extension of Telomeres |
0.0 | 0.3 | REACTOME_ACTIVATION_OF_GENES_BY_ATF4 | Genes involved in Activation of Genes by ATF4 |
0.0 | 0.3 | REACTOME_DEADENYLATION_OF_MRNA | Genes involved in Deadenylation of mRNA |