Motif ID: Stat4_Stat3_Stat5b

Z-value: 0.993

Transcription factors associated with Stat4_Stat3_Stat5b:

Gene SymbolEntrez IDGene Name
Stat3 ENSMUSG00000004040.10 Stat3
Stat4 ENSMUSG00000062939.5 Stat4
Stat5b ENSMUSG00000020919.5 Stat5b

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Stat4mm10_v2_chr1_+_51987139_51987151-0.612.2e-05Click!
Stat5bmm10_v2_chr11_-_100850724_100850763-0.462.8e-03Click!
Stat3mm10_v2_chr11_-_100939457_1009394840.296.6e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Stat4_Stat3_Stat5b

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_80802789 11.500 ENSMUST00000107745.1
ENSMUST00000075316.4
Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr17_+_26715644 5.130 ENSMUST00000062519.7
ENSMUST00000144221.1
ENSMUST00000142539.1
ENSMUST00000151681.1
Crebrf



CREB3 regulatory factor



chrX_-_61185558 5.099 ENSMUST00000166381.1
Cdr1
cerebellar degeneration related antigen 1
chr4_-_64046925 4.209 ENSMUST00000107377.3
Tnc
tenascin C
chr4_-_108031938 3.908 ENSMUST00000106708.1
Podn
podocan
chr16_-_74411776 3.764 ENSMUST00000116586.2
Robo2
roundabout homolog 2 (Drosophila)
chr4_-_108032069 3.477 ENSMUST00000106709.2
Podn
podocan
chr19_-_5797410 3.380 ENSMUST00000173314.1
Malat1
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chr1_+_34005872 3.266 ENSMUST00000182296.1
Dst
dystonin
chr4_+_148602527 3.176 ENSMUST00000105701.2
ENSMUST00000052060.6
Masp2

mannan-binding lectin serine peptidase 2

chr16_-_74411292 3.035 ENSMUST00000117200.1
Robo2
roundabout homolog 2 (Drosophila)
chr13_-_67755132 2.965 ENSMUST00000091520.6
Zfp85-rs1
zinc finger protein 85, related sequence 1
chr5_+_88886809 2.921 ENSMUST00000148750.1
Slc4a4
solute carrier family 4 (anion exchanger), member 4
chr17_-_68004075 2.917 ENSMUST00000024840.5
Arhgap28
Rho GTPase activating protein 28
chr12_+_11265867 2.858 ENSMUST00000020931.5
Smc6
structural maintenance of chromosomes 6
chr13_-_67755192 2.847 ENSMUST00000144183.1
Zfp85-rs1
zinc finger protein 85, related sequence 1
chr16_-_23988852 2.842 ENSMUST00000023151.5
Bcl6
B cell leukemia/lymphoma 6
chr7_-_78577771 2.820 ENSMUST00000039438.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr5_-_34513892 2.819 ENSMUST00000114359.1
ENSMUST00000030991.7
ENSMUST00000087737.3
Tnip2


TNFAIP3 interacting protein 2


chr2_+_3424123 2.736 ENSMUST00000061852.5
ENSMUST00000100463.3
ENSMUST00000102988.3
ENSMUST00000115066.1
Dclre1c



DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae)



chr8_-_105326252 2.687 ENSMUST00000070508.7
Lrrc29
leucine rich repeat containing 29
chr3_+_96576984 2.652 ENSMUST00000148290.1
Gm16253
predicted gene 16253
chr10_-_95417099 2.638 ENSMUST00000135822.1
Socs2
suppressor of cytokine signaling 2
chr1_-_64121389 2.578 ENSMUST00000055001.3
Klf7
Kruppel-like factor 7 (ubiquitous)
chr7_+_28180272 2.529 ENSMUST00000173223.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr10_+_13966268 2.513 ENSMUST00000015645.4
Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr7_+_28180226 2.491 ENSMUST00000172467.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr6_+_115134899 2.382 ENSMUST00000009538.5
ENSMUST00000169345.1
Syn2

synapsin II

chr11_+_78499087 2.379 ENSMUST00000017488.4
Vtn
vitronectin
chr9_+_107296843 2.372 ENSMUST00000167072.1
Cish
cytokine inducible SH2-containing protein
chr10_+_69925766 2.320 ENSMUST00000182269.1
ENSMUST00000183261.1
ENSMUST00000183074.1
Ank3


ankyrin 3, epithelial


chr7_+_141476374 2.265 ENSMUST00000117634.1
Tspan4
tetraspanin 4
chr10_+_69925800 2.221 ENSMUST00000182029.1
Ank3
ankyrin 3, epithelial
chr3_-_85741389 2.180 ENSMUST00000094148.4
Fam160a1
family with sequence similarity 160, member A1
chr7_+_24112314 2.177 ENSMUST00000120006.1
ENSMUST00000005413.3
Zfp112

zinc finger protein 112

chr11_-_107915041 2.070 ENSMUST00000039071.2
Cacng5
calcium channel, voltage-dependent, gamma subunit 5
chr1_-_135688094 2.057 ENSMUST00000112103.1
Nav1
neuron navigator 1
chr10_+_69925954 2.048 ENSMUST00000181974.1
ENSMUST00000182795.1
ENSMUST00000182437.1
Ank3


ankyrin 3, epithelial


chr18_+_65873478 2.030 ENSMUST00000025395.8
ENSMUST00000173530.1
Grp

gastrin releasing peptide

chr2_-_65529275 1.911 ENSMUST00000126837.1
Scn3a
sodium channel, voltage-gated, type III, alpha
chr4_-_140617062 1.886 ENSMUST00000154979.1
Arhgef10l
Rho guanine nucleotide exchange factor (GEF) 10-like
chr11_-_77787747 1.884 ENSMUST00000092883.2
Gm10277
predicted gene 10277
chr8_+_25532125 1.882 ENSMUST00000167764.1
Fgfr1
fibroblast growth factor receptor 1
chr10_-_95416850 1.853 ENSMUST00000020215.9
Socs2
suppressor of cytokine signaling 2
chr3_-_107760221 1.845 ENSMUST00000153114.1
ENSMUST00000118593.1
ENSMUST00000120243.1
Csf1


colony stimulating factor 1 (macrophage)


chr3_+_33799791 1.812 ENSMUST00000099153.3
Ttc14
tetratricopeptide repeat domain 14
chr1_+_136624901 1.745 ENSMUST00000047734.8
ENSMUST00000112046.1
Zfp281

zinc finger protein 281

chr2_-_120970706 1.720 ENSMUST00000028728.5
Ubr1
ubiquitin protein ligase E3 component n-recognin 1
chr17_-_43667015 1.713 ENSMUST00000024705.4
Slc25a27
solute carrier family 25, member 27
chr11_-_48871344 1.691 ENSMUST00000049519.3
Irgm1
immunity-related GTPase family M member 1
chr5_+_14025305 1.639 ENSMUST00000073957.6
Sema3e
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr10_+_128909866 1.637 ENSMUST00000026407.7
Cd63
CD63 antigen
chr17_-_51826562 1.633 ENSMUST00000024720.4
ENSMUST00000129667.1
ENSMUST00000156051.1
ENSMUST00000169480.1
ENSMUST00000148559.1
Satb1




special AT-rich sequence binding protein 1




chr14_+_70890099 1.620 ENSMUST00000022699.8
Gfra2
glial cell line derived neurotrophic factor family receptor alpha 2
chr7_+_24134148 1.605 ENSMUST00000056549.7
Zfp235
zinc finger protein 235
chr2_+_130405256 1.596 ENSMUST00000110281.1
ENSMUST00000028898.3
1700020A23Rik

RIKEN cDNA 1700020A23 gene

chr16_+_91647859 1.553 ENSMUST00000119368.1
ENSMUST00000114037.2
ENSMUST00000114036.2
ENSMUST00000122302.1
Son



Son DNA binding protein



chr1_-_64121456 1.528 ENSMUST00000142009.1
ENSMUST00000114086.1
Klf7

Kruppel-like factor 7 (ubiquitous)

chr9_+_20868628 1.521 ENSMUST00000043911.7
A230050P20Rik
RIKEN cDNA A230050P20 gene
chr10_+_69785507 1.494 ENSMUST00000182993.1
Ank3
ankyrin 3, epithelial
chr1_-_155812859 1.447 ENSMUST00000035325.8
Qsox1
quiescin Q6 sulfhydryl oxidase 1
chr13_-_41847482 1.445 ENSMUST00000072012.3
Adtrp
androgen dependent TFPI regulating protein
chr2_-_104257400 1.431 ENSMUST00000141159.1
D430041D05Rik
RIKEN cDNA D430041D05 gene
chr10_+_128303322 1.373 ENSMUST00000005825.6
Pan2
PAN2 polyA specific ribonuclease subunit homolog (S. cerevisiae)
chr11_-_72207413 1.367 ENSMUST00000108505.1
4933427D14Rik
RIKEN cDNA 4933427D14 gene
chr1_-_155812805 1.351 ENSMUST00000111764.2
Qsox1
quiescin Q6 sulfhydryl oxidase 1
chr7_-_105399991 1.320 ENSMUST00000118726.1
ENSMUST00000074686.7
ENSMUST00000122327.1
ENSMUST00000179474.1
ENSMUST00000048079.6
Fam160a2




family with sequence similarity 160, member A2




chr13_-_41847626 1.303 ENSMUST00000121404.1
Adtrp
androgen dependent TFPI regulating protein
chr2_-_38287347 1.296 ENSMUST00000102787.3
Dennd1a
DENN/MADD domain containing 1A
chr16_-_67620880 1.285 ENSMUST00000114292.1
ENSMUST00000120898.1
Cadm2

cell adhesion molecule 2

chr2_-_77519565 1.261 ENSMUST00000111830.2
Zfp385b
zinc finger protein 385B
chr14_-_55106547 1.261 ENSMUST00000036041.8
Ap1g2
adaptor protein complex AP-1, gamma 2 subunit
chrX_-_47892396 1.256 ENSMUST00000153548.2
Smarca1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr9_-_82975475 1.253 ENSMUST00000034787.5
Phip
pleckstrin homology domain interacting protein
chr13_+_83738874 1.237 ENSMUST00000052354.4
C130071C03Rik
RIKEN cDNA C130071C03 gene
chr16_-_20426322 1.233 ENSMUST00000115547.2
ENSMUST00000096199.4
Abcc5

ATP-binding cassette, sub-family C (CFTR/MRP), member 5

chr13_+_14063776 1.230 ENSMUST00000129488.1
ENSMUST00000110536.1
ENSMUST00000110534.1
ENSMUST00000039538.8
ENSMUST00000110533.1
Arid4b




AT rich interactive domain 4B (RBP1-like)




chr2_-_132578244 1.225 ENSMUST00000110142.1
Gpcpd1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr8_+_104831572 1.222 ENSMUST00000059449.6
Ces2b
carboxyesterase 2B
chr3_-_88000350 1.221 ENSMUST00000090971.5
Bcan
brevican
chr11_-_101785252 1.219 ENSMUST00000164750.1
ENSMUST00000107176.1
ENSMUST00000017868.6
Etv4


ets variant gene 4 (E1A enhancer binding protein, E1AF)


chr2_-_132578155 1.217 ENSMUST00000110136.1
ENSMUST00000124107.1
ENSMUST00000060955.5
Gpcpd1


glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)


chr3_-_51560816 1.211 ENSMUST00000037141.7
Setd7
SET domain containing (lysine methyltransferase) 7
chr7_+_28179469 1.210 ENSMUST00000085901.6
ENSMUST00000172761.1
Dyrk1b

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b

chr19_+_34550664 1.209 ENSMUST00000149829.1
ENSMUST00000102826.3
Ifit2

interferon-induced protein with tetratricopeptide repeats 2

chr18_+_23415400 1.196 ENSMUST00000115832.2
ENSMUST00000047954.7
Dtna

dystrobrevin alpha

chr9_+_59750876 1.181 ENSMUST00000136740.1
ENSMUST00000135298.1
ENSMUST00000128341.1
Myo9a


myosin IXa


chr19_-_46327121 1.173 ENSMUST00000041391.4
ENSMUST00000096029.5
Psd

pleckstrin and Sec7 domain containing

chr7_-_128461630 1.173 ENSMUST00000106226.2
Tial1
Tia1 cytotoxic granule-associated RNA binding protein-like 1
chr10_+_20312461 1.171 ENSMUST00000092678.3
ENSMUST00000043881.5
Bclaf1

BCL2-associated transcription factor 1

chr4_+_11704439 1.170 ENSMUST00000108304.2
Gem
GTP binding protein (gene overexpressed in skeletal muscle)
chr2_+_84734050 1.131 ENSMUST00000090729.2
Ypel4
yippee-like 4 (Drosophila)
chr18_-_23041641 1.121 ENSMUST00000097651.3
Nol4
nucleolar protein 4
chr16_-_20730544 1.120 ENSMUST00000076422.5
Thpo
thrombopoietin
chr10_-_54075730 1.119 ENSMUST00000105469.1
ENSMUST00000003843.8
Man1a

mannosidase 1, alpha

chr13_+_109260481 1.104 ENSMUST00000153234.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr12_+_85473883 1.098 ENSMUST00000021674.6
Fos
FBJ osteosarcoma oncogene
chr4_+_136310991 1.093 ENSMUST00000084219.5
Hnrnpr
heterogeneous nuclear ribonucleoprotein R
chrX_-_160994665 1.092 ENSMUST00000087104.4
Cdkl5
cyclin-dependent kinase-like 5
chr15_-_54919961 1.087 ENSMUST00000167541.2
ENSMUST00000041591.9
ENSMUST00000173516.1
Enpp2


ectonucleotide pyrophosphatase/phosphodiesterase 2


chr15_+_64817694 1.084 ENSMUST00000180105.1
Gm21798
predicted gene, 21798
chr4_+_49521176 1.084 ENSMUST00000042964.6
ENSMUST00000107696.1
Zfp189

zinc finger protein 189

chr9_+_107296682 1.084 ENSMUST00000168260.1
Cish
cytokine inducible SH2-containing protein
chr12_-_64965496 1.083 ENSMUST00000021331.7
Klhl28
kelch-like 28
chr2_-_38287174 1.060 ENSMUST00000130472.1
Dennd1a
DENN/MADD domain containing 1A
chrX_+_73064787 1.060 ENSMUST00000060418.6
Pnma3
paraneoplastic antigen MA3
chr4_-_126325672 1.059 ENSMUST00000102616.1
Tekt2
tektin 2
chr11_+_49203465 1.054 ENSMUST00000150284.1
ENSMUST00000109197.1
ENSMUST00000151228.1
Zfp62


zinc finger protein 62


chr4_+_130308595 1.044 ENSMUST00000070532.7
Fabp3
fatty acid binding protein 3, muscle and heart
chr16_-_67620805 1.044 ENSMUST00000120594.1
Cadm2
cell adhesion molecule 2
chr11_-_69695802 1.041 ENSMUST00000108649.1
ENSMUST00000174159.1
ENSMUST00000181810.1
BC096441

Tnfsf12
cDNA sequence BC096441

tumor necrosis factor (ligand) superfamily, member 12
chr7_+_29768552 1.022 ENSMUST00000032802.4
Zfp84
zinc finger protein 84
chr13_-_110280103 1.019 ENSMUST00000167824.1
Rab3c
RAB3C, member RAS oncogene family
chr17_+_34145231 1.019 ENSMUST00000171231.1
H2-DMb2
histocompatibility 2, class II, locus Mb2
chr5_-_86172747 1.016 ENSMUST00000039373.7
Uba6
ubiquitin-like modifier activating enzyme 6
chr18_+_32067729 1.015 ENSMUST00000025243.3
Iws1
IWS1 homolog (S. cerevisiae)
chr13_-_77135416 1.010 ENSMUST00000159462.1
ENSMUST00000151524.2
Ankrd32

ankyrin repeat domain 32

chr12_+_82616885 1.010 ENSMUST00000161801.1
Rgs6
regulator of G-protein signaling 6
chr8_+_12915879 1.008 ENSMUST00000110876.2
ENSMUST00000110879.2
Mcf2l

mcf.2 transforming sequence-like

chr7_+_120843551 1.002 ENSMUST00000106489.1
ENSMUST00000143279.1
Eef2k

eukaryotic elongation factor-2 kinase

chr1_-_130729249 0.999 ENSMUST00000171479.1
Pfkfb2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr14_+_76504478 0.995 ENSMUST00000022587.9
ENSMUST00000134109.1
Tsc22d1

TSC22 domain family, member 1

chr11_+_49203285 0.993 ENSMUST00000109198.1
ENSMUST00000137061.2
Zfp62

zinc finger protein 62

chr10_+_40349265 0.992 ENSMUST00000044672.4
ENSMUST00000095743.2
Cdk19

cyclin-dependent kinase 19

chr4_+_136310936 0.990 ENSMUST00000131671.1
Hnrnpr
heterogeneous nuclear ribonucleoprotein R
chr1_+_11414089 0.981 ENSMUST00000048613.7
ENSMUST00000171690.2
ENSMUST00000137824.1
ENSMUST00000135014.1
ENSMUST00000179089.1
A830018L16Rik



A830018L16Rik
RIKEN cDNA A830018L16 gene



RIKEN cDNA A830018L16 gene
chr12_+_3426857 0.973 ENSMUST00000111215.3
ENSMUST00000092003.5
ENSMUST00000144247.2
ENSMUST00000153102.2
Asxl2



additional sex combs like 2 (Drosophila)



chr16_-_20426375 0.973 ENSMUST00000079158.6
Abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr12_+_74297474 0.953 ENSMUST00000072100.3
Dbpht2
DNA binding protein with his-thr domain
chr15_+_6708372 0.951 ENSMUST00000061656.6
Rictor
RPTOR independent companion of MTOR, complex 2
chr2_-_33371400 0.948 ENSMUST00000113164.1
ENSMUST00000091039.2
ENSMUST00000042615.6
Ralgps1


Ral GEF with PH domain and SH3 binding motif 1


chr17_-_57247632 0.946 ENSMUST00000005975.6
Gpr108
G protein-coupled receptor 108
chr18_+_90510122 0.945 ENSMUST00000025515.6
Tmx3
thioredoxin-related transmembrane protein 3
chr7_+_27233003 0.935 ENSMUST00000003860.6
ENSMUST00000108378.3
Adck4

aarF domain containing kinase 4

chr10_-_86732409 0.922 ENSMUST00000070435.4
Fabp3-ps1
fatty acid binding protein 3, muscle and heart, pseudogene 1
chr16_-_20425881 0.915 ENSMUST00000077867.3
Abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr13_+_96542602 0.914 ENSMUST00000179226.1
Col4a3bp
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
chr15_-_78305603 0.912 ENSMUST00000096356.3
Csf2rb2
colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)
chr4_+_136310952 0.911 ENSMUST00000105850.1
ENSMUST00000148843.3
Hnrnpr

heterogeneous nuclear ribonucleoprotein R

chr7_+_6474088 0.910 ENSMUST00000056144.5
Olfr1346
olfactory receptor 1346
chr7_+_25268387 0.905 ENSMUST00000169392.1
Cic
capicua homolog (Drosophila)
chr11_-_48871408 0.904 ENSMUST00000097271.2
Irgm1
immunity-related GTPase family M member 1
chr10_-_54075702 0.901 ENSMUST00000105470.1
Man1a
mannosidase 1, alpha
chr13_+_96542727 0.897 ENSMUST00000077672.4
ENSMUST00000109444.2
Col4a3bp

collagen, type IV, alpha 3 (Goodpasture antigen) binding protein

chr7_-_24316590 0.884 ENSMUST00000108436.1
ENSMUST00000032673.8
Zfp94

zinc finger protein 94

chr12_+_52699297 0.879 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chr8_+_46739745 0.876 ENSMUST00000034041.7
Irf2
interferon regulatory factor 2
chr7_-_128461168 0.875 ENSMUST00000106228.1
Tial1
Tia1 cytotoxic granule-associated RNA binding protein-like 1
chr16_+_21794384 0.861 ENSMUST00000180830.1
1300002E11Rik
RIKEN cDNA 1300002E11 gene
chr2_+_11172080 0.858 ENSMUST00000114853.1
Prkcq
protein kinase C, theta
chr4_-_116017854 0.856 ENSMUST00000049095.5
Faah
fatty acid amide hydrolase
chr3_+_7612702 0.856 ENSMUST00000181286.1
Gm16685
predicted gene, 16685
chr7_+_30095150 0.854 ENSMUST00000130526.1
ENSMUST00000108200.1
Zfp260

zinc finger protein 260

chr18_+_37320374 0.854 ENSMUST00000078271.2
Pcdhb5
protocadherin beta 5
chr13_+_77135513 0.847 ENSMUST00000168779.1
2210408I21Rik
RIKEN cDNA 2210408I21 gene
chr14_+_76504185 0.841 ENSMUST00000177207.1
Tsc22d1
TSC22 domain family, member 1
chr11_+_23306910 0.835 ENSMUST00000137823.1
Usp34
ubiquitin specific peptidase 34
chr2_-_127584668 0.827 ENSMUST00000110368.2
ENSMUST00000077422.5
Zfp661

zinc finger protein 661

chr11_-_98729374 0.827 ENSMUST00000126565.1
ENSMUST00000100500.2
ENSMUST00000017354.6
Med24


mediator complex subunit 24


chr18_-_34624562 0.818 ENSMUST00000003876.3
ENSMUST00000115766.1
ENSMUST00000097626.3
ENSMUST00000115765.1
Brd8



bromodomain containing 8



chr3_-_69004503 0.818 ENSMUST00000107812.1
Ift80
intraflagellar transport 80
chr2_-_180824596 0.804 ENSMUST00000148700.1
Gm14340
predicted gene 14340
chr8_-_105568298 0.803 ENSMUST00000005849.5
Agrp
agouti related protein
chr2_-_144527341 0.798 ENSMUST00000163701.1
ENSMUST00000081982.5
Dzank1

double zinc ribbon and ankyrin repeat domains 1

chr16_+_38089001 0.791 ENSMUST00000023507.6
Gsk3b
glycogen synthase kinase 3 beta
chr2_-_33371486 0.789 ENSMUST00000113165.1
Ralgps1
Ral GEF with PH domain and SH3 binding motif 1
chr18_+_42511496 0.783 ENSMUST00000025375.7
Tcerg1
transcription elongation regulator 1 (CA150)
chr10_-_127288851 0.781 ENSMUST00000156208.1
ENSMUST00000026476.6
Mbd6

methyl-CpG binding domain protein 6

chr7_+_27591705 0.778 ENSMUST00000167435.1
Akt2
thymoma viral proto-oncogene 2
chr16_+_91372783 0.774 ENSMUST00000023693.7
ENSMUST00000134491.2
ENSMUST00000117836.1
Ifnar2


interferon (alpha and beta) receptor 2


chr1_+_104768510 0.770 ENSMUST00000062528.8
Cdh20
cadherin 20
chr7_+_113514085 0.767 ENSMUST00000122890.1
Far1
fatty acyl CoA reductase 1
chr13_-_85288999 0.762 ENSMUST00000109552.2
Rasa1
RAS p21 protein activator 1
chr11_+_101245996 0.758 ENSMUST00000129680.1
Ramp2
receptor (calcitonin) activity modifying protein 2
chr7_+_82335732 0.755 ENSMUST00000173287.1
Adamtsl3
ADAMTS-like 3
chr18_+_36559972 0.755 ENSMUST00000134146.1
Ankhd1
ankyrin repeat and KH domain containing 1
chr11_-_3193388 0.752 ENSMUST00000081318.6
ENSMUST00000142315.1
ENSMUST00000118627.1
ENSMUST00000066391.7
Sfi1



Sfi1 homolog, spindle assembly associated (yeast)



chr13_+_112464070 0.747 ENSMUST00000183663.1
ENSMUST00000184311.1
ENSMUST00000183886.1
Il6st


interleukin 6 signal transducer


chr13_+_109903089 0.745 ENSMUST00000120664.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr6_+_48395652 0.743 ENSMUST00000077093.4
Krba1
KRAB-A domain containing 1
chr10_+_29143996 0.742 ENSMUST00000092629.2
Soga3
SOGA family member 3
chr7_-_102018139 0.734 ENSMUST00000094134.3
Il18bp
interleukin 18 binding protein
chr6_+_3498382 0.726 ENSMUST00000001412.10
ENSMUST00000170873.3
ENSMUST00000184752.1
ENSMUST00000164052.3
Ccdc132



coiled-coil domain containing 132



chr15_-_89170688 0.723 ENSMUST00000060808.9
Plxnb2
plexin B2
chr7_-_99182681 0.721 ENSMUST00000033001.4
Dgat2
diacylglycerol O-acyltransferase 2
chr11_+_53519920 0.721 ENSMUST00000147912.1
Sept8
septin 8
chr10_+_128908907 0.719 ENSMUST00000105229.1
Cd63
CD63 antigen
chr9_+_57130690 0.716 ENSMUST00000160147.1
ENSMUST00000161663.1
ENSMUST00000034836.9
ENSMUST00000161182.1
Man2c1



mannosidase, alpha, class 2C, member 1



chr6_+_149309391 0.710 ENSMUST00000130664.1
ENSMUST00000046689.6
2810474O19Rik

RIKEN cDNA 2810474O19 gene

chr2_-_104493690 0.708 ENSMUST00000111124.1
Hipk3
homeodomain interacting protein kinase 3
chr6_+_149309444 0.700 ENSMUST00000100765.4
2810474O19Rik
RIKEN cDNA 2810474O19 gene
chrX_-_47892432 0.696 ENSMUST00000141084.2
Smarca1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr10_-_18234930 0.695 ENSMUST00000052648.8
ENSMUST00000080860.6
ENSMUST00000173243.1
Ccdc28a


coiled-coil domain containing 28A


chr17_+_45433823 0.685 ENSMUST00000181149.1
B230354K17Rik
RIKEN cDNA B230354K17 gene
chr11_+_53519871 0.684 ENSMUST00000120878.2
Sept8
septin 8
chr6_+_34598500 0.680 ENSMUST00000079391.3
ENSMUST00000142512.1
Cald1

caldesmon 1

chr16_+_91372865 0.675 ENSMUST00000089042.6
Ifnar2
interferon (alpha and beta) receptor 2
chr7_+_27591513 0.669 ENSMUST00000108344.2
Akt2
thymoma viral proto-oncogene 2
chr3_-_69004475 0.669 ENSMUST00000154741.1
ENSMUST00000148031.1
Ift80

intraflagellar transport 80

chr5_+_98180866 0.662 ENSMUST00000112959.1
Prdm8
PR domain containing 8

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 6.8 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
1.1 4.2 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
1.0 5.1 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.9 2.8 GO:0043379 memory T cell differentiation(GO:0043379) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.9 2.8 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.7 8.1 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.7 2.9 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.7 2.0 GO:0061744 motor behavior(GO:0061744) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.7 3.4 GO:0035063 nuclear speck organization(GO:0035063)
0.6 2.6 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.6 1.9 GO:0021837 motogenic signaling involved in postnatal olfactory bulb interneuron migration(GO:0021837) positive regulation of mitotic cell cycle DNA replication(GO:1903465)
0.6 1.8 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.6 1.8 GO:0035621 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
0.6 4.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.6 2.9 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.5 2.4 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.4 1.7 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.4 2.4 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.4 1.6 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.4 2.4 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.4 1.9 GO:0046684 response to pyrethroid(GO:0046684)
0.3 1.7 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.3 2.7 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.3 0.9 GO:1902605 heterotrimeric G-protein complex assembly(GO:1902605)
0.3 9.6 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.3 2.9 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.3 1.1 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.3 1.6 GO:0033139 regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033139)
0.3 0.8 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.3 1.0 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.3 1.0 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.3 1.6 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.3 1.0 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.3 1.0 GO:0021764 amygdala development(GO:0021764)
0.2 0.7 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165) regulation of interleukin-6-mediated signaling pathway(GO:0070103) negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
0.2 1.4 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.2 1.2 GO:0035754 B cell chemotaxis(GO:0035754)
0.2 1.8 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.2 16.5 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.2 0.9 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.2 2.4 GO:0097421 liver regeneration(GO:0097421)
0.2 1.4 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.2 0.8 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.2 2.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.2 0.9 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.2 0.6 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.2 0.5 GO:0097309 cap1 mRNA methylation(GO:0097309)
0.2 2.9 GO:0015701 bicarbonate transport(GO:0015701)
0.2 1.0 GO:0035630 bone mineralization involved in bone maturation(GO:0035630) positive regulation of bone development(GO:1903012)
0.2 0.5 GO:0007525 somatic muscle development(GO:0007525)
0.2 1.3 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.2 1.1 GO:1901679 nucleotide transmembrane transport(GO:1901679)
0.2 0.8 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.2 1.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.7 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.1 0.6 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 1.6 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.1 1.0 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.1 0.7 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.1 0.8 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.1 0.4 GO:2000047 regulation of cell-cell adhesion mediated by cadherin(GO:2000047) positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.1 0.3 GO:0070343 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
0.1 1.0 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 0.4 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.1 0.8 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 1.4 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 0.6 GO:0045059 positive thymic T cell selection(GO:0045059)
0.1 0.4 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.1 6.2 GO:0060612 adipose tissue development(GO:0060612)
0.1 1.2 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.1 1.7 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.5 GO:0019372 lipoxygenase pathway(GO:0019372)
0.1 0.8 GO:0008343 adult feeding behavior(GO:0008343)
0.1 0.4 GO:0010920 negative regulation of inositol phosphate biosynthetic process(GO:0010920)
0.1 1.2 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 0.3 GO:1905076 interleukin-17 secretion(GO:0072615) regulation of interleukin-17 secretion(GO:1905076)
0.1 0.3 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 0.5 GO:0032621 interleukin-18 production(GO:0032621)
0.1 0.7 GO:0006517 protein deglycosylation(GO:0006517)
0.1 0.5 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 1.8 GO:0006491 N-glycan processing(GO:0006491)
0.1 3.1 GO:0034340 response to type I interferon(GO:0034340)
0.1 3.1 GO:0061157 positive regulation of mRNA catabolic process(GO:0061014) mRNA destabilization(GO:0061157)
0.1 1.1 GO:0036159 inner dynein arm assembly(GO:0036159)
0.1 0.3 GO:0032242 regulation of nucleoside transport(GO:0032242) necroptotic signaling pathway(GO:0097527)
0.1 0.4 GO:0048539 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) bone marrow development(GO:0048539)
0.1 0.3 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 0.6 GO:0045583 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.1 1.0 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1 0.6 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.1 0.6 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.1 1.8 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 1.9 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 0.3 GO:0032053 ciliary basal body organization(GO:0032053)
0.1 0.2 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.1 0.5 GO:0071630 trophectodermal cellular morphogenesis(GO:0001831) nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.1 0.5 GO:0000429 carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436) carbon catabolite activation of transcription(GO:0045991) regulation of response to drug(GO:2001023)
0.1 0.3 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 0.3 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.1 0.5 GO:0015862 uridine transport(GO:0015862)
0.1 0.1 GO:0032240 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.1 0.4 GO:0032196 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) transposition(GO:0032196)
0.1 2.1 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 0.3 GO:0070269 pyroptosis(GO:0070269)
0.1 0.5 GO:0031100 organ regeneration(GO:0031100)
0.1 0.3 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.1 0.2 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 0.6 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1 0.2 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.1 0.5 GO:0030242 pexophagy(GO:0030242)
0.1 0.4 GO:0006172 ADP biosynthetic process(GO:0006172)
0.1 0.5 GO:0043615 astrocyte cell migration(GO:0043615)
0.1 0.4 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.1 1.1 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.1 0.6 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 0.7 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 1.4 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 0.5 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.1 1.4 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 0.7 GO:0021540 corpus callosum morphogenesis(GO:0021540)
0.1 0.2 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.1 0.4 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.1 1.8 GO:0007099 centriole replication(GO:0007099)
0.1 0.2 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.4 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 1.9 GO:0008333 endosome to lysosome transport(GO:0008333)
0.1 0.5 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.1 1.6 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 0.4 GO:0035635 entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.0 0.5 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130) negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.0 0.2 GO:0045072 regulation of interferon-gamma biosynthetic process(GO:0045072) positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.4 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.2 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 2.3 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.6 GO:1902459 asymmetric neuroblast division(GO:0055059) positive regulation of stem cell population maintenance(GO:1902459)
0.0 1.2 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.4 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.6 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 1.1 GO:0042088 T-helper 1 type immune response(GO:0042088)
0.0 0.7 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.5 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:0070162 adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163) negative regulation of adiponectin secretion(GO:0070164)
0.0 0.6 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0 0.2 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.2 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.2 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 2.6 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 2.2 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.6 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.1 GO:0060729 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162) intestinal epithelial structure maintenance(GO:0060729)
0.0 0.1 GO:0070829 heterochromatin maintenance(GO:0070829)
0.0 0.1 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
0.0 1.0 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.7 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 1.3 GO:0017145 stem cell division(GO:0017145)
0.0 0.5 GO:0048266 behavioral response to pain(GO:0048266)
0.0 1.1 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 0.1 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.9 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.1 GO:0040010 positive regulation of growth rate(GO:0040010)
0.0 0.4 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.8 GO:0044030 regulation of DNA methylation(GO:0044030)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 1.5 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.1 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.1 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0036337 Fas signaling pathway(GO:0036337)
0.0 0.3 GO:0048820 hair follicle maturation(GO:0048820)
0.0 0.6 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.6 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.2 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.1 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.1 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.6 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.2 GO:0099645 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628) protein localization to postsynaptic specialization membrane(GO:0099633) neurotransmitter receptor localization to postsynaptic specialization membrane(GO:0099645)
0.0 0.5 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.7 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 2.5 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.0 GO:1990090 response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.2 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 0.2 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.5 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.1 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.5 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 0.2 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.2 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 1.2 GO:0032092 positive regulation of protein binding(GO:0032092)
0.0 0.3 GO:0042407 cristae formation(GO:0042407)
0.0 0.4 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.0 0.2 GO:0015809 arginine transport(GO:0015809)
0.0 0.1 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.3 GO:0051642 centrosome localization(GO:0051642)
0.0 0.6 GO:0046889 positive regulation of lipid biosynthetic process(GO:0046889)
0.0 0.5 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.4 GO:0021871 forebrain regionalization(GO:0021871)
0.0 0.2 GO:0048535 lymph node development(GO:0048535)
0.0 0.6 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 0.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.5 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 0.1 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.1 GO:0046688 response to copper ion(GO:0046688)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0035061 interchromatin granule(GO:0035061)
0.8 3.3 GO:0031673 H zone(GO:0031673)
0.6 1.8 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.6 2.4 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.5 11.5 GO:0032279 asymmetric synapse(GO:0032279)
0.5 3.2 GO:0005796 Golgi lumen(GO:0005796)
0.5 2.0 GO:0090537 CERF complex(GO:0090537)
0.5 1.4 GO:0031251 PAN complex(GO:0031251)
0.4 7.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.2 0.7 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.2 3.8 GO:0005614 interstitial matrix(GO:0005614)
0.2 1.6 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 2.7 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.2 6.8 GO:0030673 axolemma(GO:0030673)
0.2 0.6 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.2 1.3 GO:0070695 FHF complex(GO:0070695)
0.2 2.6 GO:0044754 autolysosome(GO:0044754)
0.2 1.1 GO:0035976 AP1 complex(GO:0035976)
0.2 0.6 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 0.8 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1 2.0 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 1.2 GO:0030478 actin cap(GO:0030478)
0.1 2.1 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 3.3 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.6 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.1 0.5 GO:0070876 SOSS complex(GO:0070876)
0.1 2.1 GO:0043194 axon initial segment(GO:0043194)
0.1 1.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.6 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 1.0 GO:0001739 sex chromatin(GO:0001739)
0.1 1.1 GO:0044294 dendritic growth cone(GO:0044294)
0.1 0.6 GO:0071203 WASH complex(GO:0071203)
0.1 1.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 3.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 0.8 GO:1990909 Wnt signalosome(GO:1990909)
0.1 0.8 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.8 GO:0000812 Swr1 complex(GO:0000812)
0.1 1.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 2.2 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 0.6 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 2.3 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 0.3 GO:0061702 inflammasome complex(GO:0061702)
0.1 0.5 GO:0005827 polar microtubule(GO:0005827)
0.1 0.4 GO:0071439 clathrin complex(GO:0071439)
0.1 0.4 GO:0000322 storage vacuole(GO:0000322)
0.1 2.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 1.0 GO:0031932 TORC2 complex(GO:0031932)
0.1 2.4 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.1 1.0 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.5 GO:0035102 PRC1 complex(GO:0035102)
0.0 1.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.3 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.4 GO:0045095 keratin filament(GO:0045095)
0.0 0.4 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.3 GO:0097342 death-inducing signaling complex(GO:0031264) ripoptosome(GO:0097342)
0.0 0.2 GO:0016600 flotillin complex(GO:0016600)
0.0 0.1 GO:0001651 dense fibrillar component(GO:0001651)
0.0 1.2 GO:0051233 spindle midzone(GO:0051233)
0.0 0.2 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 1.6 GO:0031201 SNARE complex(GO:0031201)
0.0 2.0 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.9 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 2.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.3 GO:0061617 MICOS complex(GO:0061617)
0.0 0.3 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.3 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.6 GO:0031430 M band(GO:0031430)
0.0 1.6 GO:0016528 sarcoplasm(GO:0016528)
0.0 0.6 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 2.5 GO:0016605 PML body(GO:0016605)
0.0 0.0 GO:0008091 spectrin(GO:0008091)
0.0 1.2 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 5.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.4 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 1.6 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.2 GO:0043034 costamere(GO:0043034)
0.0 0.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 2.3 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.8 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.1 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.6 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.1 GO:0072562 blood microparticle(GO:0072562)
0.0 1.9 GO:0001650 fibrillar center(GO:0001650)
0.0 0.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.1 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.8 GO:0043235 receptor complex(GO:0043235)
0.0 0.6 GO:0043198 dendritic shaft(GO:0043198)
0.0 9.7 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.1 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.4 GO:0016592 mediator complex(GO:0016592)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 11.5 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
1.0 4.9 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.8 4.2 GO:0045545 syndecan binding(GO:0045545)
0.8 6.8 GO:0008046 axon guidance receptor activity(GO:0008046)
0.7 3.7 GO:0016972 thiol oxidase activity(GO:0016972)
0.7 2.0 GO:0070615 nucleosome-dependent ATPase activity(GO:0070615)
0.6 2.4 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.6 2.8 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.5 1.6 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.4 1.4 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.4 1.4 GO:0019962 interferon receptor activity(GO:0004904) type I interferon receptor activity(GO:0004905) type I interferon binding(GO:0019962)
0.3 1.0 GO:0004686 elongation factor-2 kinase activity(GO:0004686)
0.3 2.7 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.3 1.8 GO:0097001 ceramide binding(GO:0097001)
0.3 1.7 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.3 1.7 GO:0070728 leucine binding(GO:0070728)
0.2 0.7 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924)
0.2 3.0 GO:0001846 opsonin binding(GO:0001846)
0.2 0.7 GO:0048019 receptor antagonist activity(GO:0048019)
0.2 2.9 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2 0.7 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.2 1.0 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.2 1.8 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.2 1.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.2 2.9 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 0.5 GO:0031208 POZ domain binding(GO:0031208)
0.2 0.9 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.2 0.8 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.2 0.9 GO:0004984 olfactory receptor activity(GO:0004984)
0.2 0.8 GO:0097643 amylin receptor activity(GO:0097643)
0.2 1.5 GO:0050733 RS domain binding(GO:0050733)
0.1 1.6 GO:0038191 neuropilin binding(GO:0038191)
0.1 7.9 GO:0030507 spectrin binding(GO:0030507)
0.1 0.5 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.1 0.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 2.2 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 0.4 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 1.0 GO:0001848 complement binding(GO:0001848)
0.1 0.4 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 1.1 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.1 0.7 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.1 3.0 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 1.0 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 0.5 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 2.0 GO:0031402 sodium ion binding(GO:0031402)
0.1 5.9 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 0.6 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 0.7 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 0.7 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.6 GO:0043199 sulfate binding(GO:0043199)
0.1 0.5 GO:0033142 progesterone receptor binding(GO:0033142)
0.1 1.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 1.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 4.9 GO:0005518 collagen binding(GO:0005518)
0.1 0.3 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 1.0 GO:0043495 protein anchor(GO:0043495)
0.1 0.2 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.1 0.9 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.2 GO:0032052 bile acid binding(GO:0032052)
0.1 2.4 GO:0017091 AU-rich element binding(GO:0017091)
0.1 0.3 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 1.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.2 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.1 1.0 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 1.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 1.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 2.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.8 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 0.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 2.1 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 0.7 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 1.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.3 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.8 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.1 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 0.6 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.2 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.1 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.7 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.8 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.5 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 1.0 GO:0031489 myosin V binding(GO:0031489)
0.0 0.5 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 1.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.9 GO:0003823 antigen binding(GO:0003823)
0.0 0.5 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.2 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.3 GO:1901612 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.0 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 1.2 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.4 GO:0004532 exoribonuclease activity(GO:0004532) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 1.1 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.6 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 1.9 GO:0005179 hormone activity(GO:0005179)
0.0 0.8 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.5 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0070976 TIR domain binding(GO:0070976)
0.0 0.7 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.2 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.2 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 1.8 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.5 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.2 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0015173 hydrogen:amino acid symporter activity(GO:0005280) aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.6 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.3 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.1 GO:0008988 rRNA (adenine-N6-)-methyltransferase activity(GO:0008988)
0.0 0.5 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.4 GO:0070402 NADPH binding(GO:0070402)
0.0 3.3 GO:0008514 organic anion transmembrane transporter activity(GO:0008514)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 5.8 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.0 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 1.4 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.2 GO:0032813 death receptor binding(GO:0005123) tumor necrosis factor receptor superfamily binding(GO:0032813)
0.0 0.2 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.5 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 1.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.1 GO:0008430 selenium binding(GO:0008430)
0.0 0.0 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.0 0.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0035325 Toll-like receptor binding(GO:0035325)
0.0 0.7 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.6 GO:0019003 GDP binding(GO:0019003)
0.0 1.2 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 0.4 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.0 GO:0004111 creatine kinase activity(GO:0004111)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.9 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.3 3.5 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.3 12.0 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.3 8.6 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.2 1.8 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 4.4 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.1 2.4 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 3.6 PID_SHP2_PATHWAY SHP2 signaling
0.1 2.7 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 0.8 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.1 0.5 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 3.2 PID_IL4_2PATHWAY IL4-mediated signaling events
0.1 0.5 PID_GMCSF_PATHWAY GMCSF-mediated signaling events
0.1 4.5 PID_IL2_1PATHWAY IL2-mediated signaling events
0.1 1.6 SIG_IL4RECEPTOR_IN_B_LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.1 1.0 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 2.0 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.6 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 1.2 PID_CXCR3_PATHWAY CXCR3-mediated signaling events
0.0 0.7 SIG_BCR_SIGNALING_PATHWAY Members of the BCR signaling pathway
0.0 2.1 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 2.5 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.3 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.0 0.5 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.3 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 0.5 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 2.0 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 0.6 PID_CD8_TCR_PATHWAY TCR signaling in naïve CD8+ T cells
0.0 3.2 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.3 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.5 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.0 0.4 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 0.2 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 0.0 ST_TYPE_I_INTERFERON_PATHWAY Type I Interferon (alpha/beta IFN) Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.8 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.6 1.1 REACTOME_PLATELET_AGGREGATION_PLUG_FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.5 11.5 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.3 8.2 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.2 1.0 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.2 8.1 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 3.1 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.2 0.8 REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION Genes involved in Downstream signal transduction
0.2 1.9 REACTOME_SIGNALING_BY_ACTIVATED_POINT_MUTANTS_OF_FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.2 1.4 REACTOME_REGULATION_OF_IFNA_SIGNALING Genes involved in Regulation of IFNA signaling
0.2 6.4 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.1 0.3 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.1 1.0 REACTOME_PD1_SIGNALING Genes involved in PD-1 signaling
0.1 1.2 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.1 2.0 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 1.6 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.1 0.6 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 1.0 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.1 2.5 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.1 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1 2.9 REACTOME_IL1_SIGNALING Genes involved in Interleukin-1 signaling
0.1 2.0 REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.1 1.6 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.0 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 4.7 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 0.5 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.3 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.5 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.8 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.8 REACTOME_MUSCLE_CONTRACTION Genes involved in Muscle contraction
0.0 0.5 REACTOME_INTERFERON_SIGNALING Genes involved in Interferon Signaling
0.0 0.6 REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.5 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.3 REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 1.1 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.5 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.6 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 1.3 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 3.5 REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.8 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 1.6 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 3.1 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.3 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.1 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 1.4 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.0 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.7 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.4 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.1 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.8 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.2 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.3 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.4 REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.5 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.1 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules