Motif ID: Irf2_Irf1_Irf8_Irf9_Irf7

Z-value: 3.727


Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Irf1mm10_v2_chr11_+_53770458_537705090.647.7e-06Click!
Irf8mm10_v2_chr8_+_120736352_1207363850.333.3e-02Click!
Irf2mm10_v2_chr8_+_46739745_467397910.324.1e-02Click!
Irf9mm10_v2_chr14_+_55604550_55604579-0.261.0e-01Click!
Irf7mm10_v2_chr7_-_141266415_141266481-0.076.7e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Irf2_Irf1_Irf8_Irf9_Irf7

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_+_3013140 64.842 ENSMUST00000143083.2
Gm10721
predicted gene 10721
chr9_+_3034599 61.648 ENSMUST00000178641.1
Gm17535
predicted gene, 17535
chr9_+_3027439 61.081 ENSMUST00000177875.1
ENSMUST00000179982.1
Gm10717

predicted gene 10717

chr9_+_3023547 59.562 ENSMUST00000099046.3
Gm10718
predicted gene 10718
chr9_+_3017408 56.646 ENSMUST00000099049.3
Gm10719
predicted gene 10719
chr9_+_3015654 55.853 ENSMUST00000099050.3
Gm10720
predicted gene 10720
chr2_-_98667264 54.829 ENSMUST00000099683.1
Gm10800
predicted gene 10800
chr9_+_3004457 54.212 ENSMUST00000178348.1
Gm11168
predicted gene 11168
chr9_+_3000922 52.967 ENSMUST00000151376.2
Gm10722
predicted gene 10722
chr9_+_3037111 52.888 ENSMUST00000177969.1
Gm10715
predicted gene 10715
chr14_-_19418930 52.103 ENSMUST00000177817.1
Gm21738
predicted gene, 21738
chr9_+_3036877 50.404 ENSMUST00000155807.2
Gm10715
predicted gene 10715
chr9_+_3005125 47.906 ENSMUST00000179881.1
Gm11168
predicted gene 11168
chr9_+_3018753 46.124 ENSMUST00000179272.1
Gm10719
predicted gene 10719
chr9_+_3025417 45.465 ENSMUST00000075573.6
Gm10717
predicted gene 10717
chr2_+_98662227 26.293 ENSMUST00000099684.3
Gm10801
predicted gene 10801
chr19_+_36409719 20.482 ENSMUST00000062389.5
Pcgf5
polycomb group ring finger 5
chr2_-_105399286 20.414 ENSMUST00000006128.6
Rcn1
reticulocalbin 1
chr2_-_51972990 17.808 ENSMUST00000145481.1
ENSMUST00000112705.2
Nmi

N-myc (and STAT) interactor

chr11_+_119393060 16.146 ENSMUST00000131035.2
ENSMUST00000093902.5
Rnf213

ring finger protein 213

chrX_-_134161928 14.922 ENSMUST00000033611.4
Xkrx
X Kell blood group precursor related X linked
chr16_+_35938972 14.243 ENSMUST00000023622.6
ENSMUST00000114877.1
Parp9

poly (ADP-ribose) polymerase family, member 9

chr2_-_51934943 12.896 ENSMUST00000102767.1
ENSMUST00000102768.1
Rbm43

RNA binding motif protein 43

chr16_-_35939082 12.623 ENSMUST00000081933.7
ENSMUST00000114885.1
Dtx3l

deltex 3-like (Drosophila)

chr2_+_122147680 12.448 ENSMUST00000102476.4
B2m
beta-2 microglobulin
chr19_+_55741810 11.754 ENSMUST00000111657.3
ENSMUST00000061496.9
ENSMUST00000041717.7
ENSMUST00000111662.4
Tcf7l2



transcription factor 7 like 2, T cell specific, HMG box



chr14_+_14012491 10.253 ENSMUST00000022257.2
Atxn7
ataxin 7
chr4_-_156200818 8.673 ENSMUST00000085425.4
Isg15
ISG15 ubiquitin-like modifier
chr7_-_102565425 8.586 ENSMUST00000106913.1
ENSMUST00000033264.4
Trim21

tripartite motif-containing 21

chr4_-_154636831 8.533 ENSMUST00000030902.6
ENSMUST00000105637.1
ENSMUST00000070313.7
ENSMUST00000105636.1
ENSMUST00000105638.2
ENSMUST00000097759.2
ENSMUST00000124771.1
Prdm16






PR domain containing 16






chr17_+_78508063 8.423 ENSMUST00000024880.9
Vit
vitrin
chr16_-_10785525 8.103 ENSMUST00000038099.4
Socs1
suppressor of cytokine signaling 1
chr2_-_51934644 7.239 ENSMUST00000165313.1
Rbm43
RNA binding motif protein 43
chr3_-_104818539 7.126 ENSMUST00000106774.1
ENSMUST00000106775.1
ENSMUST00000166979.1
ENSMUST00000136148.1
Mov10



Moloney leukemia virus 10



chr2_-_132253227 7.107 ENSMUST00000028817.6
Pcna
proliferating cell nuclear antigen
chr6_+_57580992 6.951 ENSMUST00000031817.8
Herc6
hect domain and RLD 6
chr17_-_78882508 6.728 ENSMUST00000024884.4
Eif2ak2
eukaryotic translation initiation factor 2-alpha kinase 2
chr16_+_35938470 6.722 ENSMUST00000114878.1
Parp9
poly (ADP-ribose) polymerase family, member 9
chr11_-_48871408 6.544 ENSMUST00000097271.2
Irgm1
immunity-related GTPase family M member 1
chr5_-_137116177 6.483 ENSMUST00000054384.5
ENSMUST00000152207.1
Trim56

tripartite motif-containing 56

chrX_+_85048309 6.295 ENSMUST00000113991.1
ENSMUST00000113992.2
Dmd

dystrophin, muscular dystrophy

chr9_+_38718263 6.284 ENSMUST00000001544.5
ENSMUST00000118144.1
Vwa5a

von Willebrand factor A domain containing 5A

chr13_+_49504774 6.243 ENSMUST00000051504.7
Ecm2
extracellular matrix protein 2, female organ and adipocyte specific
chr6_-_39118211 6.073 ENSMUST00000038398.6
Parp12
poly (ADP-ribose) polymerase family, member 12
chr11_+_88999376 6.060 ENSMUST00000100627.2
ENSMUST00000107896.3
ENSMUST00000000284.6
Trim25


tripartite motif-containing 25


chr17_-_34000257 5.967 ENSMUST00000087189.6
ENSMUST00000173075.1
ENSMUST00000172760.1
ENSMUST00000172912.1
ENSMUST00000025181.10
H2-K1




histocompatibility 2, K1, K region




chr7_+_58658181 5.934 ENSMUST00000168747.1
Atp10a
ATPase, class V, type 10A
chr11_-_48871344 5.651 ENSMUST00000049519.3
Irgm1
immunity-related GTPase family M member 1
chr6_-_34317442 5.430 ENSMUST00000154655.1
ENSMUST00000102980.4
Akr1b3

aldo-keto reductase family 1, member B3 (aldose reductase)

chr4_-_40239779 5.402 ENSMUST00000037907.6
Ddx58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr13_-_81570640 5.332 ENSMUST00000109565.2
Gpr98
G protein-coupled receptor 98
chr3_-_107760221 5.329 ENSMUST00000153114.1
ENSMUST00000118593.1
ENSMUST00000120243.1
Csf1


colony stimulating factor 1 (macrophage)


chr1_-_156674290 5.322 ENSMUST00000079625.4
Tor3a
torsin family 3, member A
chr4_-_58499398 5.290 ENSMUST00000107570.1
Lpar1
lysophosphatidic acid receptor 1
chr7_+_97453204 5.205 ENSMUST00000050732.7
ENSMUST00000121987.1
Kctd14

potassium channel tetramerisation domain containing 14

chr8_-_84773381 5.079 ENSMUST00000109764.1
Nfix
nuclear factor I/X
chr18_-_39490649 5.024 ENSMUST00000115567.1
Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr17_-_58991343 4.881 ENSMUST00000025064.7
2610034M16Rik
RIKEN cDNA 2610034M16 gene
chr18_+_60293372 4.878 ENSMUST00000171297.1
F830016B08Rik
RIKEN cDNA F830016B08 gene
chr7_-_104353328 4.404 ENSMUST00000130139.1
ENSMUST00000059037.8
Trim12c

tripartite motif-containing 12C

chr6_+_121245903 4.369 ENSMUST00000032198.9
Usp18
ubiquitin specific peptidase 18
chr13_+_74639866 4.341 ENSMUST00000169114.1
Erap1
endoplasmic reticulum aminopeptidase 1
chr11_+_58199556 4.296 ENSMUST00000058704.8
ENSMUST00000035266.4
ENSMUST00000094169.4
ENSMUST00000168280.1
Irgm2
Igtp


immunity-related GTPase family M member 2
interferon gamma induced GTPase


chr7_-_25788635 4.144 ENSMUST00000002677.4
ENSMUST00000085948.4
Axl

AXL receptor tyrosine kinase

chr10_+_78069351 4.101 ENSMUST00000105393.1
Icosl
icos ligand
chr2_+_104069819 4.085 ENSMUST00000111131.2
ENSMUST00000111132.1
ENSMUST00000129749.1
Cd59b


CD59b antigen


chr12_-_80260356 4.027 ENSMUST00000021554.8
Actn1
actinin, alpha 1
chr13_+_15463837 4.014 ENSMUST00000110510.3
Gli3
GLI-Kruppel family member GLI3
chr8_+_46739745 3.972 ENSMUST00000034041.7
Irf2
interferon regulatory factor 2
chr2_+_118598209 3.965 ENSMUST00000038341.7
Bub1b
budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)
chr2_-_51973219 3.940 ENSMUST00000028314.2
Nmi
N-myc (and STAT) interactor
chr14_-_65833963 3.864 ENSMUST00000022613.9
Esco2
establishment of cohesion 1 homolog 2 (S. cerevisiae)
chr4_-_40239700 3.822 ENSMUST00000142055.1
Ddx58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr4_+_41903610 3.816 ENSMUST00000098128.3
Gm21541
predicted gene, 21541
chr19_+_9283231 3.723 ENSMUST00000088040.4
Pcna-ps2
proliferating cell nuclear antigen pseudogene 2
chr1_+_61638819 3.698 ENSMUST00000138768.1
ENSMUST00000075374.3
Pard3b

par-3 partitioning defective 3 homolog B (C. elegans)

chr16_-_23127702 3.688 ENSMUST00000115338.1
ENSMUST00000115337.1
ENSMUST00000023598.8
Rfc4


replication factor C (activator 1) 4


chr8_+_12385769 3.682 ENSMUST00000080795.8
Gm5607
predicted gene 5607
chr18_-_39489776 3.609 ENSMUST00000025300.6
Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr2_+_19371636 3.597 ENSMUST00000023856.8
Msrb2
methionine sulfoxide reductase B2
chr8_-_45333189 3.589 ENSMUST00000095328.4
Cyp4v3
cytochrome P450, family 4, subfamily v, polypeptide 3
chr4_+_42255767 3.551 ENSMUST00000178864.1
Ccl21b
chemokine (C-C motif) ligand 21B (leucine)
chr1_-_192092540 3.534 ENSMUST00000085573.6
Traf5
TNF receptor-associated factor 5
chr15_+_32920723 3.512 ENSMUST00000022871.5
Sdc2
syndecan 2
chr15_+_9436028 3.473 ENSMUST00000042360.3
Capsl
calcyphosine-like
chr11_-_82991829 3.461 ENSMUST00000092840.4
ENSMUST00000038211.5
Slfn9

schlafen 9

chr4_+_111719975 3.426 ENSMUST00000038868.7
ENSMUST00000070513.6
ENSMUST00000153746.1
Spata6


spermatogenesis associated 6


chr13_-_23430826 3.403 ENSMUST00000153753.1
ENSMUST00000141543.1
C230035I16Rik

RIKEN cDNA C230035I16 gene

chr4_+_42114817 3.376 ENSMUST00000098123.3
Gm13304
predicted gene 13304
chr12_+_103434211 3.368 ENSMUST00000079294.5
ENSMUST00000076788.5
ENSMUST00000076702.5
ENSMUST00000066701.6
ENSMUST00000085065.5
ENSMUST00000140838.1
Ifi27





interferon, alpha-inducible protein 27





chr8_+_31187317 3.302 ENSMUST00000066173.5
ENSMUST00000161788.1
ENSMUST00000110527.2
ENSMUST00000161502.1
Fut10



fucosyltransferase 10



chr3_-_135608221 3.295 ENSMUST00000132668.1
Nfkb1
nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
chr1_-_71103146 3.286 ENSMUST00000027393.7
Bard1
BRCA1 associated RING domain 1
chr3_-_79842662 3.254 ENSMUST00000029568.1
Tmem144
transmembrane protein 144
chr17_-_70851189 3.245 ENSMUST00000059775.8
Tgif1
TGFB-induced factor homeobox 1
chr17_+_33919332 3.239 ENSMUST00000025161.7
Tapbp
TAP binding protein
chr4_-_137796350 3.216 ENSMUST00000030551.4
Alpl
alkaline phosphatase, liver/bone/kidney
chr3_-_137981523 3.196 ENSMUST00000136613.1
ENSMUST00000029806.6
Dapp1

dual adaptor for phosphotyrosine and 3-phosphoinositides 1

chr5_+_117319258 3.136 ENSMUST00000111967.1
Vsig10
V-set and immunoglobulin domain containing 10
chr16_-_24393588 3.088 ENSMUST00000181640.1
1110054M08Rik
RIKEN cDNA 1110054M08 gene
chr2_+_20519776 3.018 ENSMUST00000114604.2
ENSMUST00000066509.3
Etl4

enhancer trap locus 4

chrX_-_134111852 3.009 ENSMUST00000033610.6
Nox1
NADPH oxidase 1
chr4_-_42773993 2.962 ENSMUST00000095114.4
Ccl21a
chemokine (C-C motif) ligand 21A (serine)
chr8_+_40926220 2.946 ENSMUST00000034004.9
Pdgfrl
platelet-derived growth factor receptor-like
chr1_+_52008210 2.887 ENSMUST00000027277.5
Stat4
signal transducer and activator of transcription 4
chr16_+_43363855 2.868 ENSMUST00000156367.1
Zbtb20
zinc finger and BTB domain containing 20
chr9_-_43239816 2.776 ENSMUST00000034512.5
Oaf
OAF homolog (Drosophila)
chr7_-_130547358 2.757 ENSMUST00000160289.1
Nsmce4a
non-SMC element 4 homolog A (S. cerevisiae)
chr19_-_45591820 2.716 ENSMUST00000160003.1
ENSMUST00000162879.1
Fbxw4

F-box and WD-40 domain protein 4

chr15_-_98728120 2.695 ENSMUST00000003445.6
Fkbp11
FK506 binding protein 11
chr17_-_35000746 2.683 ENSMUST00000163360.1
D17H6S56E-5
DNA segment, Chr 17, human D6S56E 5
chr19_+_43752996 2.678 ENSMUST00000026199.7
ENSMUST00000112047.3
ENSMUST00000153295.1
Cutc


cutC copper transporter homolog (E.coli)


chr11_-_89302545 2.669 ENSMUST00000061728.3
Nog
noggin
chr5_+_114896936 2.662 ENSMUST00000031542.9
ENSMUST00000146072.1
ENSMUST00000150361.1
Oasl2


2'-5' oligoadenylate synthetase-like 2


chr11_-_98625661 2.657 ENSMUST00000104933.1
Gm12355
predicted gene 12355
chr4_+_111720187 2.655 ENSMUST00000084354.3
Spata6
spermatogenesis associated 6
chr6_-_134792596 2.565 ENSMUST00000100857.3
Dusp16
dual specificity phosphatase 16
chr9_+_92542223 2.558 ENSMUST00000070522.7
ENSMUST00000160359.1
Plod2

procollagen lysine, 2-oxoglutarate 5-dioxygenase 2

chr16_-_22439719 2.556 ENSMUST00000079601.6
Etv5
ets variant gene 5
chr11_-_68386821 2.537 ENSMUST00000021284.3
Ntn1
netrin 1
chr6_-_23839137 2.520 ENSMUST00000166458.2
ENSMUST00000142913.2
ENSMUST00000115357.1
ENSMUST00000069074.7
ENSMUST00000115361.2
ENSMUST00000018122.7
ENSMUST00000115355.1
ENSMUST00000115356.2
Cadps2







Ca2+-dependent activator protein for secretion 2







chr5_+_117319292 2.515 ENSMUST00000086464.4
Vsig10
V-set and immunoglobulin domain containing 10
chr13_+_34162953 2.477 ENSMUST00000124996.1
ENSMUST00000147632.1
Psmg4

proteasome (prosome, macropain) assembly chaperone 4

chr16_+_43364145 2.470 ENSMUST00000148775.1
Zbtb20
zinc finger and BTB domain containing 20
chr13_-_41358990 2.432 ENSMUST00000163623.1
Nedd9
neural precursor cell expressed, developmentally down-regulated gene 9
chr1_+_131867224 2.402 ENSMUST00000112386.1
ENSMUST00000027693.7
Rab7l1

RAB7, member RAS oncogene family-like 1

chrX_+_101254528 2.399 ENSMUST00000062000.4
Foxo4
forkhead box O4
chr1_-_20820213 2.385 ENSMUST00000053266.9
Mcm3
minichromosome maintenance deficient 3 (S. cerevisiae)
chr14_+_54936456 2.374 ENSMUST00000037814.6
Cmtm5
CKLF-like MARVEL transmembrane domain containing 5
chr14_-_26066961 2.346 ENSMUST00000100818.5
Tmem254c
transmembrane protein 254c
chr9_+_38719024 2.330 ENSMUST00000129598.1
Vwa5a
von Willebrand factor A domain containing 5A
chr11_-_49051122 2.310 ENSMUST00000132768.1
ENSMUST00000101295.2
ENSMUST00000093152.1
9930111J21Rik2


RIKEN cDNA 9930111J21 gene 2


chr2_+_52038005 2.305 ENSMUST00000065927.5
Tnfaip6
tumor necrosis factor alpha induced protein 6
chr13_-_97747373 2.287 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr1_+_175632169 2.209 ENSMUST00000097458.3
Kmo
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr1_-_155146755 2.209 ENSMUST00000027744.8
Mr1
major histocompatibility complex, class I-related
chr5_+_108132885 2.205 ENSMUST00000047677.7
Ccdc18
coiled-coil domain containing 18
chr6_-_54593139 2.187 ENSMUST00000046520.6
Fkbp14
FK506 binding protein 14
chr3_-_67375163 2.173 ENSMUST00000166353.1
Gm17402
predicted gene, 17402
chr10_+_52690496 2.172 ENSMUST00000105473.2
Slc35f1
solute carrier family 35, member F1
chr3_+_81932601 2.160 ENSMUST00000029649.2
Ctso
cathepsin O
chr6_+_53573364 2.152 ENSMUST00000047450.7
Creb5
cAMP responsive element binding protein 5
chr1_+_156035392 2.113 ENSMUST00000111757.3
Tor1aip2
torsin A interacting protein 2
chr12_+_116077720 2.109 ENSMUST00000011315.3
Vipr2
vasoactive intestinal peptide receptor 2
chrX_+_42151002 2.097 ENSMUST00000123245.1
Stag2
stromal antigen 2
chr4_+_52439235 2.090 ENSMUST00000117280.1
ENSMUST00000102915.3
ENSMUST00000142227.1
Smc2


structural maintenance of chromosomes 2


chr17_+_35424842 2.087 ENSMUST00000174699.1
H2-Q6
histocompatibility 2, Q region locus 6
chr7_-_144939823 2.058 ENSMUST00000093962.4
Ccnd1
cyclin D1
chr17_-_31277327 2.005 ENSMUST00000024832.7
Rsph1
radial spoke head 1 homolog (Chlamydomonas)
chr17_+_35439155 2.001 ENSMUST00000071951.6
ENSMUST00000078205.7
ENSMUST00000116598.3
ENSMUST00000076256.7
H2-Q7



histocompatibility 2, Q region locus 7



chr5_+_3343893 2.001 ENSMUST00000165117.1
Cdk6
cyclin-dependent kinase 6
chr6_+_134929118 1.996 ENSMUST00000185152.1
ENSMUST00000184504.1
RP23-45G16.5

RP23-45G16.5

chr11_-_77894096 1.995 ENSMUST00000017597.4
Pipox
pipecolic acid oxidase
chr11_-_48979278 1.989 ENSMUST00000141200.1
ENSMUST00000097494.2
ENSMUST00000093153.1
9930111J21Rik1


RIKEN cDNA 9930111J21 gene 1


chr3_+_137671524 1.985 ENSMUST00000166899.2
Gm21962
predicted gene, 21962
chr11_+_90030295 1.965 ENSMUST00000092788.3
Tmem100
transmembrane protein 100
chr13_-_23710714 1.964 ENSMUST00000091707.6
ENSMUST00000006787.7
ENSMUST00000091706.6
Hfe


hemochromatosis


chr14_-_122465677 1.958 ENSMUST00000039118.6
Zic5
zinc finger protein of the cerebellum 5
chr17_+_37270214 1.945 ENSMUST00000038580.6
H2-M3
histocompatibility 2, M region locus 3
chr1_-_45503282 1.934 ENSMUST00000086430.4
Col5a2
collagen, type V, alpha 2
chrX_-_106485214 1.911 ENSMUST00000039447.7
Fndc3c1
fibronectin type III domain containing 3C1
chr15_+_25752860 1.900 ENSMUST00000022882.5
ENSMUST00000135173.1
Myo10

myosin X

chr18_-_39489880 1.882 ENSMUST00000152853.1
Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr16_+_42907563 1.863 ENSMUST00000151244.1
ENSMUST00000114694.2
Zbtb20

zinc finger and BTB domain containing 20

chr2_+_27676440 1.842 ENSMUST00000129514.1
Rxra
retinoid X receptor alpha
chr3_+_127791374 1.820 ENSMUST00000171621.1
Tifa
TRAF-interacting protein with forkhead-associated domain
chr10_+_93831555 1.810 ENSMUST00000095333.4
Usp44
ubiquitin specific peptidase 44
chr15_+_79892397 1.792 ENSMUST00000175714.1
ENSMUST00000109620.3
ENSMUST00000165537.1
Apobec3


apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3


chr10_+_4611971 1.792 ENSMUST00000105590.1
ENSMUST00000067086.7
Esr1

estrogen receptor 1 (alpha)

chr13_-_104863883 1.783 ENSMUST00000043061.4
Fam159b
family with sequence similarity 159, member B
chr9_-_90255927 1.766 ENSMUST00000144646.1
Tbc1d2b
TBC1 domain family, member 2B
chr2_-_73485733 1.758 ENSMUST00000102680.1
Wipf1
WAS/WASL interacting protein family, member 1
chr16_+_24393350 1.728 ENSMUST00000038053.6
Lpp
LIM domain containing preferred translocation partner in lipoma
chr1_-_66863265 1.707 ENSMUST00000027153.5
Acadl
acyl-Coenzyme A dehydrogenase, long-chain
chr6_+_134929089 1.679 ENSMUST00000183867.1
ENSMUST00000184991.1
ENSMUST00000183905.1
RP23-45G16.5


RP23-45G16.5


chr13_+_51846673 1.676 ENSMUST00000021903.2
Gadd45g
growth arrest and DNA-damage-inducible 45 gamma
chr2_+_167062934 1.642 ENSMUST00000125674.1
1500012F01Rik
RIKEN cDNA 1500012F01 gene
chr6_+_138140298 1.637 ENSMUST00000008684.4
Mgst1
microsomal glutathione S-transferase 1
chr17_+_43389436 1.622 ENSMUST00000113599.1
Gpr116
G protein-coupled receptor 116
chr2_+_156840966 1.616 ENSMUST00000109564.1
Tgif2
TGFB-induced factor homeobox 2
chr19_-_12765447 1.607 ENSMUST00000112933.1
Cntf
ciliary neurotrophic factor
chr16_-_38341812 1.595 ENSMUST00000114740.2
ENSMUST00000023501.8
Maats1

MYCBP-associated, testis expressed 1

chr6_-_72380416 1.589 ENSMUST00000101285.3
ENSMUST00000074231.3
Vamp5

vesicle-associated membrane protein 5

chr15_+_57694651 1.586 ENSMUST00000096430.4
Zhx2
zinc fingers and homeoboxes 2
chrX_+_75095854 1.582 ENSMUST00000033776.8
Dkc1
dyskeratosis congenita 1, dyskerin
chr1_+_58802492 1.577 ENSMUST00000165549.1
Casp8
caspase 8
chr17_+_34597852 1.565 ENSMUST00000174496.2
ENSMUST00000015596.3
ENSMUST00000173992.1
Ager


advanced glycosylation end product-specific receptor


chr14_-_79481268 1.558 ENSMUST00000022601.5
Wbp4
WW domain binding protein 4
chr12_-_52006490 1.558 ENSMUST00000085404.3
ENSMUST00000021339.7
Dtd2

D-tyrosyl-tRNA deacylase 2

chr6_+_128362919 1.556 ENSMUST00000073316.6
Foxm1
forkhead box M1
chr13_+_56609516 1.536 ENSMUST00000045173.8
Tgfbi
transforming growth factor, beta induced
chr11_+_115603920 1.535 ENSMUST00000058109.8
Mrps7
mitchondrial ribosomal protein S7
chr11_-_5878207 1.535 ENSMUST00000102922.3
Pold2
polymerase (DNA directed), delta 2, regulatory subunit
chr18_+_61045139 1.532 ENSMUST00000025522.4
ENSMUST00000115274.1
Pdgfrb

platelet derived growth factor receptor, beta polypeptide

chr7_+_67655414 1.526 ENSMUST00000107470.1
Ttc23
tetratricopeptide repeat domain 23
chr13_+_23531044 1.521 ENSMUST00000102972.3
Hist1h4h
histone cluster 1, H4h
chr18_+_56432116 1.499 ENSMUST00000070166.5
Gramd3
GRAM domain containing 3
chrX_+_75096039 1.495 ENSMUST00000131155.1
ENSMUST00000132000.1
Dkc1

dyskeratosis congenita 1, dyskerin

chr7_-_140049140 1.463 ENSMUST00000172775.2
Msx3
msh homeobox 3
chr9_+_51621425 1.460 ENSMUST00000089534.4
Gm7293
predicted gene 7293

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
7.4 22.3 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
4.6 45.6 GO:0060330 regulation of response to interferon-gamma(GO:0060330)
3.6 14.4 GO:0034759 regulation of iron ion transport(GO:0034756) regulation of iron ion transmembrane transport(GO:0034759)
2.3 9.2 GO:0009597 detection of virus(GO:0009597)
2.1 10.5 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
2.1 6.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
1.9 1.9 GO:0002481 antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481)
1.9 5.6 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
1.8 5.4 GO:0006059 hexitol metabolic process(GO:0006059) alditol biosynthetic process(GO:0019401)
1.8 7.1 GO:1902990 leading strand elongation(GO:0006272) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
1.7 7.0 GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
1.5 16.6 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
1.5 11.8 GO:0048625 myoblast fate commitment(GO:0048625)
1.5 4.4 GO:0042097 interleukin-4 biosynthetic process(GO:0042097) regulation of interleukin-4 biosynthetic process(GO:0045402)
1.5 10.3 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
1.5 7.3 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
1.5 8.7 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
1.4 4.1 GO:0097350 neutrophil clearance(GO:0097350)
1.3 4.0 GO:0060364 frontal suture morphogenesis(GO:0060364)
1.3 5.3 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
1.3 10.0 GO:0032020 ISG15-protein conjugation(GO:0032020)
1.1 3.3 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
1.1 8.6 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
1.0 2.9 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.9 3.6 GO:0030091 protein repair(GO:0030091)
0.9 4.4 GO:0080184 response to stilbenoid(GO:0035634) response to phenylpropanoid(GO:0080184)
0.8 8.5 GO:1900225 NLRP3 inflammasome complex assembly(GO:0044546) regulation of NLRP3 inflammasome complex assembly(GO:1900225)
0.8 3.3 GO:1903416 negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137) regulation of calcidiol 1-monooxygenase activity(GO:0060558) response to glycoside(GO:1903416)
0.8 4.1 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.8 3.9 GO:0034421 post-translational protein acetylation(GO:0034421)
0.8 3.0 GO:0072592 regulation of integrin biosynthetic process(GO:0045113) oxygen metabolic process(GO:0072592)
0.7 2.2 GO:0019441 tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) quinolinate biosynthetic process(GO:0019805) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218) kynurenine metabolic process(GO:0070189)
0.7 2.1 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.7 1.3 GO:0009814 defense response, incompatible interaction(GO:0009814)
0.7 2.7 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.7 2.0 GO:0006553 lysine metabolic process(GO:0006553)
0.6 1.9 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.6 2.5 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.6 3.1 GO:0090669 snoRNA guided rRNA pseudouridine synthesis(GO:0000454) telomerase RNA stabilization(GO:0090669)
0.6 3.6 GO:0032196 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) transposition(GO:0032196)
0.6 1.8 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.6 9.2 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.5 0.5 GO:0071336 regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.5 4.3 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.5 1.6 GO:1905203 regulation of connective tissue replacement(GO:1905203)
0.5 1.5 GO:0035441 cell migration involved in vasculogenesis(GO:0035441) metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
0.5 1.4 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.5 1.4 GO:0090289 regulation of osteoclast proliferation(GO:0090289)
0.5 1.4 GO:0033566 gamma-tubulin complex localization(GO:0033566)
0.5 1.8 GO:0006447 regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994)
0.5 3.2 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.4 1.3 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.4 1.6 GO:0006982 response to lipid hydroperoxide(GO:0006982) cellular response to lipid hydroperoxide(GO:0071449)
0.4 1.2 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.4 1.9 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.4 3.8 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.4 0.7 GO:0003274 endocardial cushion fusion(GO:0003274)
0.4 0.7 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.4 3.3 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.4 1.1 GO:0014891 striated muscle atrophy(GO:0014891)
0.4 2.5 GO:1990504 dense core granule exocytosis(GO:1990504)
0.3 1.0 GO:0072092 ureteric bud invasion(GO:0072092)
0.3 1.7 GO:0042758 long-chain fatty acid catabolic process(GO:0042758)
0.3 1.0 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.3 1.0 GO:0045014 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594)
0.3 3.4 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.3 1.3 GO:1903463 regulation of mitotic cell cycle DNA replication(GO:1903463)
0.3 4.9 GO:0051639 actin filament network formation(GO:0051639)
0.3 0.6 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.3 2.4 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.3 1.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.3 6.5 GO:0044458 motile cilium assembly(GO:0044458)
0.3 5.3 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.3 1.2 GO:0015889 cobalamin transport(GO:0015889)
0.3 2.0 GO:0019532 oxalate transport(GO:0019532)
0.3 1.4 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.3 2.0 GO:0044838 cell quiescence(GO:0044838)
0.3 1.1 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.3 1.4 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.3 2.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.3 1.0 GO:0097211 prolactin secretion(GO:0070459) response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.3 2.1 GO:0070141 response to UV-A(GO:0070141)
0.3 3.3 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.3 11.0 GO:0010390 histone monoubiquitination(GO:0010390)
0.2 7.1 GO:0006379 mRNA cleavage(GO:0006379)
0.2 2.0 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.2 1.2 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.2 1.7 GO:0042095 interferon-gamma biosynthetic process(GO:0042095)
0.2 0.7 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.2 0.9 GO:0006244 pyrimidine nucleotide catabolic process(GO:0006244) pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.2 0.7 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.2 4.9 GO:0038092 nodal signaling pathway(GO:0038092)
0.2 1.1 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.2 0.7 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.2 0.9 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.2 1.1 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.2 0.6 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.2 5.4 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.2 0.8 GO:0032901 positive regulation of neurotrophin production(GO:0032901)
0.2 1.2 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.2 0.8 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.2 1.0 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460)
0.2 0.2 GO:1904959 regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959)
0.2 0.8 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.2 1.4 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.2 0.5 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.2 0.9 GO:0051026 chiasma assembly(GO:0051026)
0.2 0.9 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.2 0.5 GO:0000966 RNA 5'-end processing(GO:0000966)
0.2 1.1 GO:0003383 apical constriction(GO:0003383)
0.2 0.7 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.2 1.0 GO:0006108 malate metabolic process(GO:0006108)
0.2 2.2 GO:1904667 negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.2 0.8 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.2 0.3 GO:0045359 positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.2 0.7 GO:0072602 interleukin-4 secretion(GO:0072602)
0.2 0.8 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.2 0.5 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.2 0.5 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.2 0.8 GO:0035989 tendon development(GO:0035989)
0.2 0.3 GO:0002765 immune response-inhibiting signal transduction(GO:0002765)
0.2 1.3 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.2 1.1 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.2 5.0 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.2 0.5 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.2 1.0 GO:0044375 regulation of peroxisome size(GO:0044375)
0.2 1.6 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.2 1.5 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.2 1.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 0.4 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.1 0.6 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.1 0.6 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 0.7 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.1 1.0 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 1.6 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.1 0.6 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.1 2.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 5.0 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.1 0.4 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.1 0.4 GO:0071918 urea transmembrane transport(GO:0071918)
0.1 1.0 GO:0046851 negative regulation of bone resorption(GO:0045779) negative regulation of bone remodeling(GO:0046851)
0.1 0.6 GO:0060594 mammary gland specification(GO:0060594)
0.1 0.5 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1 1.3 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 2.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 1.2 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 1.1 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.1 0.4 GO:0071211 protein targeting to vacuole involved in autophagy(GO:0071211)
0.1 0.4 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.9 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 0.7 GO:0051096 regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
0.1 0.7 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.1 0.1 GO:0002489 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489)
0.1 12.9 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 0.5 GO:0046654 'de novo' IMP biosynthetic process(GO:0006189) tetrahydrofolate biosynthetic process(GO:0046654)
0.1 1.6 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 1.3 GO:0000212 meiotic spindle organization(GO:0000212) meiotic chromosome separation(GO:0051307)
0.1 1.5 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 1.8 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.1 0.2 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.1 0.6 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1 1.0 GO:0070932 histone H3 deacetylation(GO:0070932)
0.1 1.1 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.1 1.2 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1 0.3 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.1 0.3 GO:1902031 regulation of pentose-phosphate shunt(GO:0043456) regulation of NADP metabolic process(GO:1902031)
0.1 1.2 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.1 1.1 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 0.5 GO:0006048 glucosamine metabolic process(GO:0006041) UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 0.3 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.1 1.4 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
0.1 3.2 GO:0046677 response to antibiotic(GO:0046677)
0.1 1.5 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 0.2 GO:0090365 regulation of mRNA modification(GO:0090365)
0.1 0.4 GO:1902965 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.1 0.6 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.3 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.1 1.2 GO:0042407 cristae formation(GO:0042407)
0.1 0.2 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.1 0.2 GO:0090272 negative regulation of fibroblast growth factor production(GO:0090272)
0.1 0.4 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.1 1.0 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 2.8 GO:0071346 cellular response to interferon-gamma(GO:0071346)
0.1 0.2 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1 0.5 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 0.3 GO:0035878 nail development(GO:0035878)
0.1 0.5 GO:0032782 bile acid secretion(GO:0032782)
0.1 0.9 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 0.9 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 2.5 GO:0035082 axoneme assembly(GO:0035082)
0.1 2.9 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.1 0.4 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 0.4 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.1 1.3 GO:0016180 snRNA processing(GO:0016180)
0.1 3.1 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 0.9 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 0.1 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.1 0.4 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 0.6 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 0.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.4 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.1 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.1 2.0 GO:0006270 DNA replication initiation(GO:0006270)
0.1 0.2 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.0 0.8 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.9 GO:0030575 nuclear body organization(GO:0030575)
0.0 1.1 GO:0035067 negative regulation of histone acetylation(GO:0035067)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:0061357 Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356) positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.4 GO:0030539 male genitalia development(GO:0030539)
0.0 0.7 GO:0051984 positive regulation of chromosome segregation(GO:0051984)
0.0 3.6 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 1.0 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.4 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.9 GO:0030225 macrophage differentiation(GO:0030225)
0.0 1.6 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.0 0.7 GO:0000271 polysaccharide biosynthetic process(GO:0000271)
0.0 0.2 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.2 GO:0021678 third ventricle development(GO:0021678)
0.0 1.9 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.1 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0 0.4 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 1.0 GO:0048662 negative regulation of smooth muscle cell proliferation(GO:0048662)
0.0 0.5 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 3.1 GO:0019395 fatty acid oxidation(GO:0019395)
0.0 0.4 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.5 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.2 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.2 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.5 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.3 GO:0009062 fatty acid catabolic process(GO:0009062)
0.0 0.9 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.1 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.2 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.2 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 0.1 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960) mitochondrial RNA 3'-end processing(GO:0000965)
0.0 0.2 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 0.1 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 0.2 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.6 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 3.2 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.0 2.1 GO:0032092 positive regulation of protein binding(GO:0032092)
0.0 0.2 GO:2000194 regulation of female gonad development(GO:2000194)
0.0 0.3 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.2 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.4 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.5 GO:0044783 mitotic G1 DNA damage checkpoint(GO:0031571) G1 DNA damage checkpoint(GO:0044783)
0.0 0.3 GO:0007096 regulation of exit from mitosis(GO:0007096) uterus development(GO:0060065)
0.0 0.1 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 0.1 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
0.0 0.4 GO:0055012 ventricular cardiac muscle cell differentiation(GO:0055012)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.0 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.1 GO:0046098 guanine metabolic process(GO:0046098)
0.0 5.1 GO:0043010 camera-type eye development(GO:0043010)
0.0 0.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.2 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.0 0.9 GO:0001654 eye development(GO:0001654)
0.0 0.6 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.4 GO:0046718 viral entry into host cell(GO:0046718)
0.0 0.1 GO:1990403 embryonic brain development(GO:1990403)
0.0 1.7 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.6 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.1 GO:0042574 isoprenoid catabolic process(GO:0008300) retinal metabolic process(GO:0042574)
0.0 0.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.1 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.5 GO:0010107 potassium ion import(GO:0010107)
0.0 1.7 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.4 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.0 0.8 GO:0006278 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.0 0.0 GO:0015867 ATP transport(GO:0015867)
0.0 0.3 GO:0007094 mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
0.0 0.2 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 1.9 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.1 GO:0090003 regulation of Golgi to plasma membrane protein transport(GO:0042996) regulation of establishment of protein localization to plasma membrane(GO:0090003)
0.0 0.5 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.9 GO:0051453 regulation of intracellular pH(GO:0051453)
0.0 0.8 GO:0001843 neural tube closure(GO:0001843) tube closure(GO:0060606)
0.0 0.1 GO:0042572 retinol metabolic process(GO:0042572)
0.0 169.4 GO:0008150 biological_process(GO:0008150)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.1 GO:0070557 PCNA-p21 complex(GO:0070557)
2.3 27.1 GO:0042612 MHC class I protein complex(GO:0042612)
1.8 5.3 GO:1990682 CSF1-CSF1R complex(GO:1990682)
1.4 5.4 GO:0097454 Schwann cell microvillus(GO:0097454)
1.3 11.8 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
1.0 4.0 GO:0032127 dense core granule membrane(GO:0032127)
0.9 14.7 GO:0005614 interstitial matrix(GO:0005614)
0.9 13.0 GO:0044754 secondary lysosome(GO:0005767) autolysosome(GO:0044754)
0.8 4.2 GO:1990462 omegasome(GO:1990462)
0.8 3.1 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.8 3.0 GO:0071438 invadopodium membrane(GO:0071438)
0.7 4.3 GO:0005663 DNA replication factor C complex(GO:0005663)
0.6 1.9 GO:0005588 collagen type V trimer(GO:0005588)
0.6 2.8 GO:1990357 terminal web(GO:1990357)
0.5 3.3 GO:0070531 BRCA1-A complex(GO:0070531)
0.5 1.6 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.5 1.6 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.5 1.5 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.5 3.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.4 2.9 GO:0042825 TAP complex(GO:0042825)
0.4 1.6 GO:0031084 BLOC-2 complex(GO:0031084)
0.4 2.8 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.4 6.0 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.4 4.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.4 1.4 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.3 4.8 GO:0035631 CD40 receptor complex(GO:0035631)
0.3 4.0 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.3 3.9 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.3 4.7 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.3 20.4 GO:0031519 PcG protein complex(GO:0031519)
0.3 1.4 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.3 1.4 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.3 2.1 GO:0042611 MHC protein complex(GO:0042611)
0.3 1.8 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.3 2.0 GO:0001520 outer dense fiber(GO:0001520)
0.2 0.9 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.2 2.1 GO:0000796 condensin complex(GO:0000796)
0.2 2.1 GO:0030478 actin cap(GO:0030478)
0.2 0.9 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.2 0.9 GO:0097450 astrocyte end-foot(GO:0097450)
0.2 1.3 GO:0030896 checkpoint clamp complex(GO:0030896)
0.2 0.8 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.2 1.5 GO:0031105 septin complex(GO:0031105)
0.2 9.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.2 0.9 GO:0072487 MSL complex(GO:0072487)
0.2 0.9 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.2 0.5 GO:0000814 ESCRT II complex(GO:0000814)
0.2 2.4 GO:0042555 MCM complex(GO:0042555)
0.2 0.8 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.2 1.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.2 6.8 GO:0016235 aggresome(GO:0016235)
0.1 1.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 1.7 GO:0043657 host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657)
0.1 1.2 GO:0061617 MICOS complex(GO:0061617)
0.1 1.1 GO:0033269 internode region of axon(GO:0033269)
0.1 1.7 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 0.7 GO:0045179 apical cortex(GO:0045179)
0.1 11.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 0.8 GO:0005638 lamin filament(GO:0005638)
0.1 1.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.5 GO:0044327 dendritic spine head(GO:0044327)
0.1 1.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 0.8 GO:0042382 paraspeckles(GO:0042382)
0.1 0.4 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 1.2 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.8 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.1 3.5 GO:0016592 mediator complex(GO:0016592)
0.1 1.3 GO:0032039 integrator complex(GO:0032039)
0.1 0.8 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 1.5 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.4 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.7 GO:0045298 tubulin complex(GO:0045298)
0.1 1.0 GO:0005922 connexon complex(GO:0005922)
0.1 0.3 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 5.8 GO:0036126 sperm flagellum(GO:0036126)
0.1 5.2 GO:0005604 basement membrane(GO:0005604)
0.1 9.1 GO:0005923 bicellular tight junction(GO:0005923)
0.1 0.4 GO:0097165 nuclear stress granule(GO:0097165)
0.1 1.8 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.8 GO:0045120 pronucleus(GO:0045120)
0.1 0.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.5 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.5 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.8 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 1.8 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.7 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 2.0 GO:0032590 dendrite membrane(GO:0032590)
0.1 0.7 GO:0010369 chromocenter(GO:0010369)
0.1 1.7 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.6 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.7 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.6 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.0 0.4 GO:0051286 cell tip(GO:0051286)
0.0 0.5 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 1.3 GO:0097546 ciliary base(GO:0097546)
0.0 1.0 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.4 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.4 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.5 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 1.7 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 0.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 2.3 GO:0030175 filopodium(GO:0030175)
0.0 461.0 GO:0005575 cellular_component(GO:0005575)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 10.5 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
2.4 7.3 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
2.1 6.2 GO:0070052 collagen V binding(GO:0070052)
1.7 6.7 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
1.2 6.1 GO:0032027 myosin light chain binding(GO:0032027)
1.2 5.8 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
1.1 14.7 GO:0030881 beta-2-microglobulin binding(GO:0030881)
1.0 1.0 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
1.0 3.0 GO:0030171 voltage-gated proton channel activity(GO:0030171)
1.0 3.9 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.9 3.6 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.8 3.3 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.8 3.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.8 5.3 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.7 5.9 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.7 2.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.7 6.1 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.7 8.8 GO:0031386 protein tag(GO:0031386)
0.7 11.4 GO:0017166 vinculin binding(GO:0017166)
0.7 2.0 GO:0098770 FBXO family protein binding(GO:0098770)
0.6 3.9 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.6 2.5 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.6 3.6 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.6 1.8 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.6 11.8 GO:0045295 gamma-catenin binding(GO:0045295)
0.6 12.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.5 2.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.5 2.0 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.5 2.9 GO:0046977 TAP binding(GO:0046977)
0.5 4.3 GO:0051434 BH3 domain binding(GO:0051434)
0.5 1.4 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.4 3.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.4 1.7 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.4 1.2 GO:0004658 propionyl-CoA carboxylase activity(GO:0004658)
0.4 1.2 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.4 1.6 GO:0034618 arginine binding(GO:0034618)
0.4 1.6 GO:0035877 death effector domain binding(GO:0035877)
0.4 4.3 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.4 4.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.3 4.2 GO:0031996 thioesterase binding(GO:0031996)
0.3 1.0 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.3 1.9 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.3 1.8 GO:0070644 vitamin D response element binding(GO:0070644)
0.3 1.5 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.3 1.4 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.3 0.3 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.3 8.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.2 4.9 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 0.9 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.2 0.9 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.2 0.7 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.2 6.4 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.2 4.3 GO:0001848 complement binding(GO:0001848)
0.2 0.6 GO:0005110 frizzled-2 binding(GO:0005110)
0.2 0.8 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.2 1.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 0.7 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.2 2.0 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.2 0.9 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.2 0.5 GO:0004637 phosphoribosylamine-glycine ligase activity(GO:0004637)
0.2 8.1 GO:0030332 cyclin binding(GO:0030332)
0.2 1.2 GO:0031419 cobalamin binding(GO:0031419)
0.2 0.5 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.2 0.8 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.2 4.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.2 2.7 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.2 0.8 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.2 0.5 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 3.2 GO:0070410 co-SMAD binding(GO:0070410)
0.1 0.5 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 10.5 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 3.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 3.5 GO:0070064 proline-rich region binding(GO:0070064)
0.1 1.0 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.9 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 4.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 1.6 GO:0044548 S100 protein binding(GO:0044548)
0.1 2.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 3.3 GO:0042805 actinin binding(GO:0042805)
0.1 0.8 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.1 0.7 GO:0000403 Y-form DNA binding(GO:0000403)
0.1 0.6 GO:1990715 mRNA CDS binding(GO:1990715)
0.1 0.5 GO:0031489 myosin V binding(GO:0031489)
0.1 0.9 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 1.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.6 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 0.7 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 0.4 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 0.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.4 GO:0034711 inhibin binding(GO:0034711)
0.1 0.3 GO:0043559 insulin binding(GO:0043559)
0.1 5.2 GO:0016836 hydro-lyase activity(GO:0016836)
0.1 0.7 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.1 0.3 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 4.1 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1 0.5 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.7 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.5 GO:0015288 porin activity(GO:0015288)
0.1 1.1 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.6 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 1.2 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 1.2 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.1 0.2 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.1 1.5 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.3 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.1 2.0 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 0.7 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1 6.7 GO:0046332 SMAD binding(GO:0046332)
0.1 0.5 GO:0005372 water transmembrane transporter activity(GO:0005372)
0.1 3.3 GO:0015144 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.1 0.4 GO:0015265 urea channel activity(GO:0015265)
0.1 1.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 1.1 GO:0005123 death receptor binding(GO:0005123)
0.1 1.2 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.1 0.8 GO:0032813 tumor necrosis factor receptor superfamily binding(GO:0032813)
0.1 36.5 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 0.9 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 0.4 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.4 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1 1.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 1.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 1.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 5.7 GO:0008083 growth factor activity(GO:0008083)
0.1 0.2 GO:0009881 photoreceptor activity(GO:0009881)
0.1 6.2 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1 3.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 3.0 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 2.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 1.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 3.4 GO:0046906 tetrapyrrole binding(GO:0046906)
0.1 1.0 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 2.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.4 GO:0050681 androgen receptor binding(GO:0050681)
0.1 0.2 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.3 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 1.6 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.6 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 12.0 GO:0003924 GTPase activity(GO:0003924)
0.0 0.3 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.2 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.0 0.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 1.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.6 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.6 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.4 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.0 0.3 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 1.5 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 1.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.4 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.8 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0 0.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0036004 GAF domain binding(GO:0036004)
0.0 3.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.1 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.9 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 12.2 GO:0003712 transcription cofactor activity(GO:0003712)
0.0 0.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 10.3 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.6 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.6 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 1.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 1.3 GO:0019955 cytokine binding(GO:0019955)
0.0 1.1 GO:0030594 neurotransmitter receptor activity(GO:0030594)
0.0 0.8 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.5 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 2.5 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.4 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 303.1 GO:0003674 molecular_function(GO:0003674)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 27.3 PID_IL12_2PATHWAY IL12-mediated signaling events
0.4 3.2 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.3 12.8 PID_BARD1_PATHWAY BARD1 signaling events
0.3 22.2 PID_AP1_PATHWAY AP-1 transcription factor network
0.3 2.6 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.3 14.9 PID_TCPTP_PATHWAY Signaling events mediated by TCPTP
0.2 2.1 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.2 6.4 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.2 25.1 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 4.0 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.1 8.4 PID_PLK1_PATHWAY PLK1 signaling events
0.1 2.9 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.1 2.2 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.1 4.6 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 2.4 PID_PI3KCI_AKT_PATHWAY Class I PI3K signaling events mediated by Akt
0.1 2.0 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.1 4.5 NABA_COLLAGENS Genes encoding collagen proteins
0.1 1.4 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.1 1.9 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.1 1.9 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.1 6.4 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.1 2.7 NABA_CORE_MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.1 1.8 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.1 2.6 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 1.3 PID_MYC_PATHWAY C-MYC pathway
0.1 1.0 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.1 3.7 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 1.6 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.1 3.3 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.1 0.7 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.1 0.6 PID_IL1_PATHWAY IL1-mediated signaling events
0.1 0.8 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.1 4.5 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.1 1.8 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.2 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 2.3 PID_BMP_PATHWAY BMP receptor signaling
0.0 0.9 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 1.0 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 2.1 PID_E2F_PATHWAY E2F transcription factor network
0.0 2.5 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 4.8 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.3 PID_IL3_PATHWAY IL3-mediated signaling events
0.0 0.7 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.6 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 0.9 PID_P73PATHWAY p73 transcription factor network
0.0 0.1 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.5 ST_FAS_SIGNALING_PATHWAY Fas Signaling Pathway
0.0 0.7 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.5 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 0.1 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.0 0.8 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 12.3 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
1.1 17.0 REACTOME_NFKB_ACTIVATION_THROUGH_FADD_RIP1_PATHWAY_MEDIATED_BY_CASPASE_8_AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
1.0 12.9 REACTOME_POL_SWITCHING Genes involved in Polymerase switching
0.7 9.2 REACTOME_REGULATION_OF_IFNA_SIGNALING Genes involved in Regulation of IFNA signaling
0.5 1.9 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.3 3.4 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.3 9.2 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.3 9.1 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.3 11.3 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.3 2.4 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.2 2.2 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.2 5.7 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.2 3.8 REACTOME_INHIBITION_OF_THE_PROTEOLYTIC_ACTIVITY_OF_APC_C_REQUIRED_FOR_THE_ONSET_OF_ANAPHASE_BY_MITOTIC_SPINDLE_CHECKPOINT_COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.2 3.4 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.2 1.3 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.2 4.9 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2 1.3 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.2 3.1 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.2 1.8 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.2 2.9 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.2 0.9 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.2 2.1 REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS Genes involved in Glucagon-type ligand receptors
0.2 4.0 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 1.2 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 2.4 REACTOME_DNA_STRAND_ELONGATION Genes involved in DNA strand elongation
0.1 1.4 REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 2.7 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.1 1.6 REACTOME_TRAF6_MEDIATED_NFKB_ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.1 1.2 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 4.2 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 7.0 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.1 1.2 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.1 1.0 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 4.1 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.1 6.5 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 1.7 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.8 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 0.9 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 4.2 REACTOME_AMYLOIDS Genes involved in Amyloids
0.1 1.3 REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS Genes involved in Activation of ATR in response to replication stress
0.1 0.8 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.1 1.1 REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 0.1 REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.1 1.6 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.1 0.6 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 0.5 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 0.4 REACTOME_AQUAPORIN_MEDIATED_TRANSPORT Genes involved in Aquaporin-mediated transport
0.1 1.3 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.1 0.9 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 0.4 REACTOME_ACYL_CHAIN_REMODELLING_OF_PI Genes involved in Acyl chain remodelling of PI
0.0 1.6 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 1.1 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.6 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 2.3 REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.0 0.8 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.5 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 2.8 REACTOME_GLUCOSE_METABOLISM Genes involved in Glucose metabolism
0.0 2.3 REACTOME_3_UTR_MEDIATED_TRANSLATIONAL_REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.0 3.2 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 7.2 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.7 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.3 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.6 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.8 REACTOME_PIP3_ACTIVATES_AKT_SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.3 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.3 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 1.0 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.2 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 0.2 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.0 0.2 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.5 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.4 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.2 REACTOME_INTERFERON_GAMMA_SIGNALING Genes involved in Interferon gamma signaling
0.0 1.8 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.0 0.5 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.0 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.3 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.1 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.0 0.5 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits