Motif ID: Arid5b

Z-value: 0.271


Transcription factors associated with Arid5b:

Gene SymbolEntrez IDGene Name
Arid5b ENSMUSG00000019947.9 Arid5b

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Arid5bmm10_v2_chr10_-_68278713_68278735-0.124.4e-01Click!


Activity profile for motif Arid5b.

activity profile for motif Arid5b


Sorted Z-values histogram for motif Arid5b

Sorted Z-values for motif Arid5b



Network of associatons between targets according to the STRING database.



First level regulatory network of Arid5b

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_34649987 0.990 ENSMUST00000099151.2
Sox2
SRY-box containing gene 2
chr5_+_115908644 0.908 ENSMUST00000141101.1
Cit
citron
chr4_+_105157339 0.793 ENSMUST00000064139.7
Ppap2b
phosphatidic acid phosphatase type 2B
chr12_-_91746020 0.673 ENSMUST00000166967.1
Ston2
stonin 2
chr14_-_47394253 0.635 ENSMUST00000177822.1
Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr12_-_10900296 0.560 ENSMUST00000085735.2
Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chr2_+_25180737 0.519 ENSMUST00000104999.2
Nrarp
Notch-regulated ankyrin repeat protein
chr1_+_88227005 0.456 ENSMUST00000061013.6
ENSMUST00000113130.1
Mroh2a

maestro heat-like repeat family member 2A

chr13_+_23533869 0.449 ENSMUST00000073261.2
Hist1h2af
histone cluster 1, H2af
chr10_-_6980376 0.430 ENSMUST00000105617.1
Ipcef1
interaction protein for cytohesin exchange factors 1
chr4_+_132638987 0.388 ENSMUST00000135299.1
ENSMUST00000081726.6
ENSMUST00000180250.1
ENSMUST00000020197.7
ENSMUST00000079157.4
Eya3




eyes absent 3 homolog (Drosophila)




chr3_-_95882193 0.388 ENSMUST00000159863.1
ENSMUST00000159739.1
ENSMUST00000036418.3
Gm129


predicted gene 129


chr15_-_55548164 0.360 ENSMUST00000165356.1
Mrpl13
mitochondrial ribosomal protein L13
chr6_+_120666388 0.355 ENSMUST00000112686.1
Cecr2
cat eye syndrome chromosome region, candidate 2
chr9_+_87022014 0.346 ENSMUST00000168529.2
ENSMUST00000174724.1
ENSMUST00000173126.1
Cyb5r4


cytochrome b5 reductase 4


chr3_-_95882031 0.332 ENSMUST00000161994.1
Gm129
predicted gene 129
chr1_+_180568913 0.327 ENSMUST00000027777.6
Parp1
poly (ADP-ribose) polymerase family, member 1
chr18_-_15063560 0.272 ENSMUST00000168989.1
Kctd1
potassium channel tetramerisation domain containing 1
chrX_+_140456613 0.264 ENSMUST00000033809.3
Prps1
phosphoribosyl pyrophosphate synthetase 1
chr4_-_75278246 0.259 ENSMUST00000030103.8
Tmem261
transmembrane protein 261
chr10_+_94576254 0.255 ENSMUST00000117929.1
Tmcc3
transmembrane and coiled coil domains 3
chr13_+_21735055 0.247 ENSMUST00000087714.4
Hist1h4j
histone cluster 1, H4j
chr5_-_31697598 0.243 ENSMUST00000031018.7
Rbks
ribokinase
chr9_+_21196705 0.236 ENSMUST00000003395.9
Pde4a
phosphodiesterase 4A, cAMP specific
chr1_+_180330470 0.236 ENSMUST00000070181.6
Itpkb
inositol 1,4,5-trisphosphate 3-kinase B
chr3_-_19264959 0.230 ENSMUST00000121951.1
Pde7a
phosphodiesterase 7A
chr4_-_129662442 0.213 ENSMUST00000003828.4
Kpna6
karyopherin (importin) alpha 6
chr15_-_44428303 0.210 ENSMUST00000038719.6
Nudcd1
NudC domain containing 1
chr15_-_13173607 0.189 ENSMUST00000036439.4
Cdh6
cadherin 6
chr18_+_62662108 0.172 ENSMUST00000163259.1
Gm17732
predicted gene, 17732
chr3_-_95882232 0.161 ENSMUST00000161866.1
Gm129
predicted gene 129
chr16_+_32431225 0.156 ENSMUST00000115140.1
Pcyt1a
phosphate cytidylyltransferase 1, choline, alpha isoform
chr8_-_79399513 0.154 ENSMUST00000066091.7
ENSMUST00000109885.1
ENSMUST00000066081.3
Smad1


SMAD family member 1


chrM_+_8600 0.145 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chr9_-_45984816 0.141 ENSMUST00000172450.1
Pafah1b2
platelet-activating factor acetylhydrolase, isoform 1b, subunit 2
chr12_+_108792946 0.136 ENSMUST00000021692.7
Yy1
YY1 transcription factor
chr12_+_110601439 0.120 ENSMUST00000018851.7
Dync1h1
dynein cytoplasmic 1 heavy chain 1
chr9_-_106789130 0.119 ENSMUST00000046502.5
Rad54l2
RAD54 like 2 (S. cerevisiae)
chr15_+_37233036 0.117 ENSMUST00000161405.1
ENSMUST00000022895.8
ENSMUST00000161532.1
Grhl2


grainyhead-like 2 (Drosophila)


chrX_-_157492280 0.111 ENSMUST00000112529.1
Sms
spermine synthase
chr3_-_89998656 0.106 ENSMUST00000079724.4
Hax1
HCLS1 associated X-1
chr11_+_108682602 0.105 ENSMUST00000106718.3
ENSMUST00000106715.1
ENSMUST00000106724.3
Cep112


centrosomal protein 112


chr10_+_127420867 0.094 ENSMUST00000064793.6
R3hdm2
R3H domain containing 2
chr2_-_151744142 0.089 ENSMUST00000109869.1
Psmf1
proteasome (prosome, macropain) inhibitor subunit 1
chr2_-_84678828 0.088 ENSMUST00000111665.1
Tmx2
thioredoxin-related transmembrane protein 2
chr4_-_150909428 0.087 ENSMUST00000128075.1
ENSMUST00000105674.1
ENSMUST00000105673.1
Park7


Parkinson disease (autosomal recessive, early onset) 7


chr6_+_133105239 0.085 ENSMUST00000100864.4
2700089E24Rik
RIKEN cDNA 2700089E24 gene
chr9_+_122117338 0.074 ENSMUST00000120173.1
ENSMUST00000134949.1
ENSMUST00000119215.1
Snrk


SNF related kinase


chr8_-_119840522 0.070 ENSMUST00000168698.1
ENSMUST00000034285.6
Cotl1

coactosin-like 1 (Dictyostelium)

chr10_+_14523062 0.064 ENSMUST00000096020.5
Gm10335
predicted gene 10335
chr9_+_112227443 0.053 ENSMUST00000161216.1
2310075C17Rik
RIKEN cDNA 2310075C17 gene
chr4_+_122836236 0.053 ENSMUST00000030412.4
ENSMUST00000121870.1
ENSMUST00000097902.4
Ppt1


palmitoyl-protein thioesterase 1


chr9_-_42461414 0.045 ENSMUST00000066179.7
Tbcel
tubulin folding cofactor E-like
chrX_-_101222426 0.043 ENSMUST00000120389.1
ENSMUST00000156473.1
ENSMUST00000077876.3
Snx12


sorting nexin 12


chr7_-_101921186 0.039 ENSMUST00000106965.1
ENSMUST00000106968.1
ENSMUST00000106967.1
Lrrc51


leucine rich repeat containing 51


chr5_+_31494736 0.039 ENSMUST00000076949.6
ENSMUST00000117700.1
Gpn1

GPN-loop GTPase 1

chr3_-_19265007 0.019 ENSMUST00000091314.4
Pde7a
phosphodiesterase 7A
chr2_+_76650264 0.014 ENSMUST00000099986.2
Dfnb59
deafness, autosomal recessive 59 (human)
chr10_-_109010955 0.002 ENSMUST00000105276.1
ENSMUST00000064054.7
Syt1

synaptotagmin I


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 0.3 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.1 0.3 GO:0046101 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.1 0.2 GO:0006014 D-ribose metabolic process(GO:0006014)
0.1 0.2 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
0.1 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.4 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.5 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.1 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.0 0.9 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.1 GO:0072382 minus-end-directed vesicle transport along microtubule(GO:0072382)
0.0 0.4 GO:0001842 neural fold formation(GO:0001842)
0.0 0.1 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.1 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.1 GO:0050787 glycolate metabolic process(GO:0009441) enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) glycolate biosynthetic process(GO:0046295) detoxification of mercury ion(GO:0050787) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of cellular amino acid biosynthetic process(GO:2000284)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.0 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.0 0.2 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.7 GO:0048488 synaptic vesicle endocytosis(GO:0048488)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0090537 CERF complex(GO:0090537)
0.1 0.3 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.6 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.9 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:0002177 manchette(GO:0002177)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 0.3 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 1.0 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.3 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.1 GO:0036470 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.0 0.2 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.9 GO:0097110 scaffold protein binding(GO:0097110)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.0 0.9 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 0.6 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 0.3 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.2 PID_ALK2_PATHWAY ALK2 signaling events
0.0 0.4 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis