Motif ID: E2f1

Z-value: 6.258


Transcription factors associated with E2f1:

Gene SymbolEntrez IDGene Name
E2f1 ENSMUSG00000027490.11 E2f1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
E2f1mm10_v2_chr2_-_154569720_1545697990.851.7e-12Click!


Activity profile for motif E2f1.

activity profile for motif E2f1


Sorted Z-values histogram for motif E2f1

Sorted Z-values for motif E2f1



Network of associatons between targets according to the STRING database.



First level regulatory network of E2f1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_60893430 119.845 ENSMUST00000135107.2
Sox3
SRY-box containing gene 3
chr15_-_98004634 76.478 ENSMUST00000131560.1
ENSMUST00000088355.5
Col2a1

collagen, type II, alpha 1

chr15_-_98004695 75.465 ENSMUST00000023123.8
Col2a1
collagen, type II, alpha 1
chr14_-_79301623 70.682 ENSMUST00000022595.7
Rgcc
regulator of cell cycle
chr13_-_23761223 47.498 ENSMUST00000102964.2
Hist1h4a
histone cluster 1, H4a
chr1_-_20820213 44.288 ENSMUST00000053266.9
Mcm3
minichromosome maintenance deficient 3 (S. cerevisiae)
chr14_-_103843685 41.044 ENSMUST00000172237.1
Ednrb
endothelin receptor type B
chr10_-_78591945 40.085 ENSMUST00000040580.6
Syde1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chrY_+_90784738 39.831 ENSMUST00000179483.1
Erdr1
erythroid differentiation regulator 1
chrX_+_170009892 39.223 ENSMUST00000180251.1
Gm21887
predicted gene, 21887
chrX_+_170009659 38.843 ENSMUST00000179760.1
Gm21887
predicted gene, 21887
chr19_+_36409719 35.334 ENSMUST00000062389.5
Pcgf5
polycomb group ring finger 5
chr10_-_120476469 34.878 ENSMUST00000072777.7
ENSMUST00000159699.1
Hmga2

high mobility group AT-hook 2

chr17_+_56303396 33.623 ENSMUST00000113038.1
Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
chr2_+_70562007 32.646 ENSMUST00000094934.4
Gad1
glutamate decarboxylase 1
chr2_+_71528657 31.815 ENSMUST00000126400.1
Dlx1
distal-less homeobox 1
chr4_-_137796350 30.803 ENSMUST00000030551.4
Alpl
alkaline phosphatase, liver/bone/kidney
chr17_+_56303321 30.705 ENSMUST00000001258.8
Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
chr7_+_65862029 30.607 ENSMUST00000055576.5
ENSMUST00000098391.4
Pcsk6

proprotein convertase subtilisin/kexin type 6

chr13_-_60177357 30.177 ENSMUST00000065086.4
Gas1
growth arrest specific 1
chr10_-_128704978 29.622 ENSMUST00000026416.7
ENSMUST00000026415.7
Cdk2

cyclin-dependent kinase 2

chr19_+_38481057 28.226 ENSMUST00000182481.1
Plce1
phospholipase C, epsilon 1
chr5_+_33721724 28.004 ENSMUST00000067150.7
ENSMUST00000169212.2
ENSMUST00000114411.2
ENSMUST00000164207.3
Fgfr3



fibroblast growth factor receptor 3



chr2_+_163054682 26.232 ENSMUST00000018005.3
Mybl2
myeloblastosis oncogene-like 2
chr11_+_98907801 26.037 ENSMUST00000092706.6
Cdc6
cell division cycle 6
chr2_+_71529085 25.725 ENSMUST00000152711.1
Dlx1
distal-less homeobox 1
chr17_+_85621017 25.344 ENSMUST00000162695.2
Six3
sine oculis-related homeobox 3
chr18_-_74961252 25.299 ENSMUST00000066532.4
Lipg
lipase, endothelial
chr12_+_117843489 25.096 ENSMUST00000021592.9
Cdca7l
cell division cycle associated 7 like
chr6_+_6863769 24.809 ENSMUST00000031768.6
Dlx6
distal-less homeobox 6
chr2_+_70562147 24.609 ENSMUST00000148210.1
Gad1
glutamate decarboxylase 1
chr2_+_70562854 24.512 ENSMUST00000130998.1
Gad1
glutamate decarboxylase 1
chr5_+_45669907 23.790 ENSMUST00000117396.1
Ncapg
non-SMC condensin I complex, subunit G
chr12_+_117843873 23.444 ENSMUST00000176735.1
ENSMUST00000177339.1
Cdca7l

cell division cycle associated 7 like

chr7_+_13278778 22.936 ENSMUST00000098814.4
ENSMUST00000146998.1
ENSMUST00000185145.1
Lig1


ligase I, DNA, ATP-dependent


chr1_-_191575534 22.590 ENSMUST00000027933.5
Dtl
denticleless homolog (Drosophila)
chr12_+_8771317 21.808 ENSMUST00000020911.7
Sdc1
syndecan 1
chr17_-_56830916 21.617 ENSMUST00000002444.7
ENSMUST00000086801.5
Rfx2

regulatory factor X, 2 (influences HLA class II expression)

chr13_-_47106176 21.586 ENSMUST00000021807.6
ENSMUST00000135278.1
Dek

DEK oncogene (DNA binding)

chr12_+_24708241 21.578 ENSMUST00000020980.5
Rrm2
ribonucleotide reductase M2
chr19_+_7557473 21.565 ENSMUST00000141887.1
ENSMUST00000136756.1
Pla2g16

phospholipase A2, group XVI

chr12_+_69168808 21.246 ENSMUST00000110621.1
Lrr1
leucine rich repeat protein 1
chr14_-_47276790 21.203 ENSMUST00000111792.1
ENSMUST00000111791.1
ENSMUST00000111790.1
Wdhd1


WD repeat and HMG-box DNA binding protein 1


chr16_+_93883895 21.148 ENSMUST00000023666.4
ENSMUST00000117099.1
ENSMUST00000142316.1
Chaf1b


chromatin assembly factor 1, subunit B (p60)


chr16_-_15637277 20.755 ENSMUST00000023353.3
Mcm4
minichromosome maintenance deficient 4 homolog (S. cerevisiae)
chr18_+_4921662 20.754 ENSMUST00000143254.1
Svil
supervillin
chr15_-_103366763 20.562 ENSMUST00000023128.6
Itga5
integrin alpha 5 (fibronectin receptor alpha)
chr13_-_47105790 20.431 ENSMUST00000129352.1
Dek
DEK oncogene (DNA binding)
chr10_+_108332173 20.304 ENSMUST00000095313.3
Pawr
PRKC, apoptosis, WT1, regulator
chrX_-_52613913 20.109 ENSMUST00000069360.7
Gpc3
glypican 3
chr8_+_94179089 19.807 ENSMUST00000034215.6
Mt1
metallothionein 1
chr10_+_128232065 19.356 ENSMUST00000055539.4
ENSMUST00000105244.1
ENSMUST00000105243.2
ENSMUST00000125289.1
ENSMUST00000105242.1
Timeless




timeless circadian clock 1




chr10_+_110745433 19.320 ENSMUST00000174857.1
ENSMUST00000073781.5
ENSMUST00000173471.1
ENSMUST00000173634.1
E2f7



E2F transcription factor 7



chr3_+_87971129 19.170 ENSMUST00000160694.1
Nes
nestin
chr11_+_26387194 19.146 ENSMUST00000109509.1
ENSMUST00000136830.1
Fancl

Fanconi anemia, complementation group L

chr9_-_114844090 18.960 ENSMUST00000047013.3
Cmtm8
CKLF-like MARVEL transmembrane domain containing 8
chr9_+_65890237 18.562 ENSMUST00000045802.6
2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr3_+_87971071 18.455 ENSMUST00000090973.5
Nes
nestin
chr13_-_21750505 18.345 ENSMUST00000102983.1
Hist1h4k
histone cluster 1, H4k
chr6_+_49822710 18.260 ENSMUST00000031843.6
Npy
neuropeptide Y
chr12_+_8771405 18.209 ENSMUST00000171158.1
Sdc1
syndecan 1
chr4_+_126556935 17.657 ENSMUST00000048391.8
Clspn
claspin
chr10_-_120899067 17.482 ENSMUST00000092143.5
Msrb3
methionine sulfoxide reductase B3
chr2_+_71389239 17.273 ENSMUST00000028408.2
Hat1
histone aminotransferase 1
chr7_+_102441685 16.949 ENSMUST00000033283.9
Rrm1
ribonucleotide reductase M1
chr4_+_156203292 16.865 ENSMUST00000105140.2
AW011738
expressed sequence AW011738
chr10_-_7212222 16.714 ENSMUST00000015346.5
Cnksr3
Cnksr family member 3
chr11_+_119022962 16.651 ENSMUST00000026662.7
Cbx2
chromobox 2
chr8_+_71406003 16.590 ENSMUST00000119976.1
ENSMUST00000120725.1
Ankle1

ankyrin repeat and LEM domain containing 1

chr8_+_75109528 16.376 ENSMUST00000164309.1
Mcm5
minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)
chrX_-_52613936 16.292 ENSMUST00000114857.1
Gpc3
glypican 3
chr17_-_35516780 16.106 ENSMUST00000160885.1
ENSMUST00000159009.1
ENSMUST00000161012.1
Tcf19


transcription factor 19


chr14_-_21989475 16.070 ENSMUST00000043409.7
Zfp503
zinc finger protein 503
chr13_-_100775844 16.052 ENSMUST00000075550.3
Cenph
centromere protein H
chr6_+_117917281 16.045 ENSMUST00000180020.1
ENSMUST00000177570.1
Hnrnpf

heterogeneous nuclear ribonucleoprotein F

chr1_+_86045863 15.904 ENSMUST00000165824.1
2810459M11Rik
RIKEN cDNA 2810459M11 gene
chr2_+_91457501 15.844 ENSMUST00000028689.3
Lrp4
low density lipoprotein receptor-related protein 4
chr9_-_61946768 15.734 ENSMUST00000034815.7
Kif23
kinesin family member 23
chrX_+_71556874 15.643 ENSMUST00000123100.1
Hmgb3
high mobility group box 3
chr9_-_21798502 15.606 ENSMUST00000034717.5
Kank2
KN motif and ankyrin repeat domains 2
chrX_-_51205990 15.578 ENSMUST00000114876.2
Mbnl3
muscleblind-like 3 (Drosophila)
chr7_-_19310035 15.352 ENSMUST00000003640.2
Fosb
FBJ osteosarcoma oncogene B
chr4_+_108579445 15.332 ENSMUST00000102744.3
Orc1
origin recognition complex, subunit 1
chrY_+_90785442 15.116 ENSMUST00000177591.1
ENSMUST00000177671.1
ENSMUST00000179077.1
Erdr1


erythroid differentiation regulator 1


chr5_-_37336870 15.103 ENSMUST00000031005.4
Evc
Ellis van Creveld gene syndrome
chr13_-_55329723 15.085 ENSMUST00000021941.7
Mxd3
Max dimerization protein 3
chr1_+_92831614 15.039 ENSMUST00000045970.6
Gpc1
glypican 1
chr8_-_94918012 15.029 ENSMUST00000077955.5
Ccdc102a
coiled-coil domain containing 102A
chr7_-_144738520 14.920 ENSMUST00000118556.2
ENSMUST00000033393.8
Ano1

anoctamin 1, calcium activated chloride channel

chr7_+_144838590 14.844 ENSMUST00000105898.1
Fgf3
fibroblast growth factor 3
chr4_+_24496434 14.592 ENSMUST00000108222.2
ENSMUST00000138567.2
ENSMUST00000050446.6
Mms22l


MMS22-like, DNA repair protein


chr6_+_117916981 14.453 ENSMUST00000179478.1
Hnrnpf
heterogeneous nuclear ribonucleoprotein F
chr17_-_84187939 14.447 ENSMUST00000060366.6
Zfp36l2
zinc finger protein 36, C3H type-like 2
chr6_-_126939524 14.424 ENSMUST00000144954.1
ENSMUST00000112221.1
ENSMUST00000112220.1
Rad51ap1


RAD51 associated protein 1


chr17_+_35841491 14.392 ENSMUST00000082337.6
Mdc1
mediator of DNA damage checkpoint 1
chr6_+_134929118 14.123 ENSMUST00000185152.1
ENSMUST00000184504.1
RP23-45G16.5

RP23-45G16.5

chr7_-_102250086 13.803 ENSMUST00000106923.1
ENSMUST00000098230.4
Rhog

ras homolog gene family, member G

chr3_-_101110278 13.717 ENSMUST00000102694.3
Ptgfrn
prostaglandin F2 receptor negative regulator
chr6_+_15721087 13.634 ENSMUST00000120512.1
Mdfic
MyoD family inhibitor domain containing
chr4_+_115000156 13.555 ENSMUST00000030490.6
Stil
Scl/Tal1 interrupting locus
chr9_-_97018823 13.542 ENSMUST00000055433.4
Spsb4
splA/ryanodine receptor domain and SOCS box containing 4
chr19_-_9899450 13.479 ENSMUST00000025562.7
Incenp
inner centromere protein
chr7_-_127026479 13.363 ENSMUST00000032916.4
Maz
MYC-associated zinc finger protein (purine-binding transcription factor)
chr4_-_41697040 13.288 ENSMUST00000102962.3
ENSMUST00000084701.5
Cntfr

ciliary neurotrophic factor receptor

chr3_+_40800013 13.277 ENSMUST00000026858.5
ENSMUST00000170825.1
Plk4

polo-like kinase 4

chr3_+_40800054 13.235 ENSMUST00000168287.1
Plk4
polo-like kinase 4
chr7_-_74554474 13.201 ENSMUST00000134539.1
ENSMUST00000026897.7
ENSMUST00000098371.2
Slco3a1


solute carrier organic anion transporter family, member 3a1


chr14_+_50955992 13.142 ENSMUST00000095925.4
Pnp2
purine-nucleoside phosphorylase 2
chr19_+_7557452 13.131 ENSMUST00000025925.4
ENSMUST00000136465.1
Pla2g16

phospholipase A2, group XVI

chr4_+_89137122 13.011 ENSMUST00000058030.7
Mtap
methylthioadenosine phosphorylase
chr7_-_48881032 12.944 ENSMUST00000058745.8
E2f8
E2F transcription factor 8
chr12_+_24708984 12.905 ENSMUST00000154588.1
Rrm2
ribonucleotide reductase M2
chr2_+_172550761 12.863 ENSMUST00000099058.3
Tfap2c
transcription factor AP-2, gamma
chr2_-_30801698 12.769 ENSMUST00000050003.8
1700001O22Rik
RIKEN cDNA 1700001O22 gene
chr7_-_75782080 12.533 ENSMUST00000181224.1
AU020206
expressed sequence AU020206
chr8_-_105347885 12.532 ENSMUST00000014922.4
Fhod1
formin homology 2 domain containing 1
chr7_+_58658181 12.434 ENSMUST00000168747.1
Atp10a
ATPase, class V, type 10A
chr9_-_36726374 12.361 ENSMUST00000172702.2
ENSMUST00000172742.1
ENSMUST00000034625.5
Chek1


checkpoint kinase 1


chr7_+_45215753 12.299 ENSMUST00000033060.6
ENSMUST00000155313.1
ENSMUST00000107801.1
Tead2


TEA domain family member 2


chr17_-_40935047 12.273 ENSMUST00000087114.3
Cenpq
centromere protein Q
chr3_+_89229046 12.258 ENSMUST00000041142.3
Muc1
mucin 1, transmembrane
chr3_+_137864487 12.182 ENSMUST00000041045.7
H2afz
H2A histone family, member Z
chr8_-_122432924 12.160 ENSMUST00000017604.8
Cyba
cytochrome b-245, alpha polypeptide
chr16_-_18811615 12.135 ENSMUST00000096990.3
Cdc45
cell division cycle 45
chr2_+_72476159 12.052 ENSMUST00000102691.4
Cdca7
cell division cycle associated 7
chr12_-_56535047 12.007 ENSMUST00000178477.2
Nkx2-1
NK2 homeobox 1
chr19_+_53142756 11.976 ENSMUST00000050096.7
Add3
adducin 3 (gamma)
chr2_+_158768083 11.920 ENSMUST00000029183.2
Fam83d
family with sequence similarity 83, member D
chr4_+_126556994 11.919 ENSMUST00000147675.1
Clspn
claspin
chr8_+_40423786 11.912 ENSMUST00000049389.4
ENSMUST00000128166.1
ENSMUST00000167766.1
Zdhhc2


zinc finger, DHHC domain containing 2


chr6_+_134929089 11.891 ENSMUST00000183867.1
ENSMUST00000184991.1
ENSMUST00000183905.1
RP23-45G16.5


RP23-45G16.5


chr12_+_116405397 11.818 ENSMUST00000084828.3
Ncapg2
non-SMC condensin II complex, subunit G2
chr15_+_100228229 11.777 ENSMUST00000171869.1
Atf1
activating transcription factor 1
chr7_-_142578093 11.621 ENSMUST00000149974.1
ENSMUST00000152754.1
H19

H19 fetal liver mRNA

chr2_-_36104060 11.553 ENSMUST00000112961.3
ENSMUST00000112966.3
Lhx6

LIM homeobox protein 6

chr8_+_54077532 11.465 ENSMUST00000033919.4
Vegfc
vascular endothelial growth factor C
chr7_-_48881596 11.462 ENSMUST00000119223.1
E2f8
E2F transcription factor 8
chr5_+_123749696 11.449 ENSMUST00000031366.7
Kntc1
kinetochore associated 1
chr11_-_116335384 11.403 ENSMUST00000036215.7
Foxj1
forkhead box J1
chr2_-_160912292 11.373 ENSMUST00000109454.1
ENSMUST00000057169.4
Emilin3

elastin microfibril interfacer 3

chr2_-_157204483 11.355 ENSMUST00000029170.7
Rbl1
retinoblastoma-like 1 (p107)
chr7_-_142578139 11.312 ENSMUST00000136359.1
H19
H19 fetal liver mRNA
chr11_+_70540260 11.257 ENSMUST00000018429.5
ENSMUST00000108557.3
ENSMUST00000108556.1
Pld2


phospholipase D2


chr17_-_71526819 11.251 ENSMUST00000024851.9
Ndc80
NDC80 homolog, kinetochore complex component (S. cerevisiae)
chr18_+_60911757 11.249 ENSMUST00000040359.5
Arsi
arylsulfatase i
chr11_-_34833631 11.213 ENSMUST00000093191.2
Spdl1
spindle apparatus coiled-coil protein 1
chr4_+_128993224 11.147 ENSMUST00000030583.6
ENSMUST00000102604.4
Ak2

adenylate kinase 2

chr15_+_55557399 10.984 ENSMUST00000022998.7
Mtbp
Mdm2, transformed 3T3 cell double minute p53 binding protein
chr7_-_79617642 10.965 ENSMUST00000032766.4
Rhcg
Rhesus blood group-associated C glycoprotein
chr19_-_10203880 10.963 ENSMUST00000142241.1
ENSMUST00000116542.2
ENSMUST00000025651.5
ENSMUST00000156291.1
Fen1



flap structure specific endonuclease 1



chr16_-_18248697 10.957 ENSMUST00000115645.3
Ranbp1
RAN binding protein 1
chr1_-_21079162 10.935 ENSMUST00000037998.4
Tram2
translocating chain-associating membrane protein 2
chr2_+_72476225 10.888 ENSMUST00000157019.1
Cdca7
cell division cycle associated 7
chr17_-_24960620 10.848 ENSMUST00000024981.7
Hn1l
hematological and neurological expressed 1-like
chr13_+_23581563 10.825 ENSMUST00000102968.1
Hist1h4d
histone cluster 1, H4d
chr7_-_27337667 10.757 ENSMUST00000038618.6
ENSMUST00000108369.2
Ltbp4

latent transforming growth factor beta binding protein 4

chr8_+_95633500 10.709 ENSMUST00000034094.9
Gins3
GINS complex subunit 3 (Psf3 homolog)
chr5_+_136919137 10.704 ENSMUST00000181045.1
4933404O12Rik
RIKEN cDNA 4933404O12 gene
chr10_+_128015157 10.672 ENSMUST00000178041.1
ENSMUST00000026461.7
Prim1

DNA primase, p49 subunit

chr17_-_29264115 10.595 ENSMUST00000024802.8
Ppil1
peptidylprolyl isomerase (cyclophilin)-like 1
chr4_-_107684228 10.594 ENSMUST00000069271.4
Dmrtb1
DMRT-like family B with proline-rich C-terminal, 1
chr13_-_23551648 10.546 ENSMUST00000102971.1
Hist1h4f
histone cluster 1, H4f
chr10_+_3973086 10.493 ENSMUST00000117291.1
ENSMUST00000120585.1
ENSMUST00000043735.7
Mthfd1l


methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like


chr1_-_172206775 10.458 ENSMUST00000013842.5
ENSMUST00000111247.1
Pea15a

phosphoprotein enriched in astrocytes 15A

chrX_-_51205773 10.376 ENSMUST00000114875.1
Mbnl3
muscleblind-like 3 (Drosophila)
chr1_+_191063001 10.283 ENSMUST00000076952.5
ENSMUST00000139340.1
ENSMUST00000078259.6
Nsl1


NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)


chr16_-_4559720 10.238 ENSMUST00000005862.7
Tfap4
transcription factor AP4
chr4_-_133968611 10.221 ENSMUST00000102552.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr17_+_56040350 10.102 ENSMUST00000002914.8
Chaf1a
chromatin assembly factor 1, subunit A (p150)
chr17_+_56304313 10.068 ENSMUST00000113035.1
ENSMUST00000113039.2
ENSMUST00000142387.1
Uhrf1


ubiquitin-like, containing PHD and RING finger domains, 1


chr13_+_92354783 10.040 ENSMUST00000022218.4
Dhfr
dihydrofolate reductase
chr8_-_78508876 10.008 ENSMUST00000049245.7
Rbmxl1
RNA binding motif protein, X linked-like-1
chr4_-_95052170 9.989 ENSMUST00000058555.2
Jun
Jun oncogene
chr1_-_64737735 9.967 ENSMUST00000063982.5
ENSMUST00000116133.2
Fzd5

frizzled homolog 5 (Drosophila)

chr9_+_119357381 9.947 ENSMUST00000039610.8
Xylb
xylulokinase homolog (H. influenzae)
chr6_-_87590701 9.944 ENSMUST00000050887.7
Prokr1
prokineticin receptor 1
chr6_+_107529717 9.927 ENSMUST00000049285.8
Lrrn1
leucine rich repeat protein 1, neuronal
chrX_-_48034842 9.870 ENSMUST00000039026.7
Apln
apelin
chrX_-_143393893 9.850 ENSMUST00000166406.2
Chrdl1
chordin-like 1
chr18_+_60963517 9.800 ENSMUST00000115295.2
ENSMUST00000039904.6
Camk2a

calcium/calmodulin-dependent protein kinase II alpha

chr5_-_138171248 9.775 ENSMUST00000153867.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr13_-_64153194 9.744 ENSMUST00000059817.4
ENSMUST00000117241.1
Zfp367

zinc finger protein 367

chr7_-_144738478 9.738 ENSMUST00000121758.1
Ano1
anoctamin 1, calcium activated chloride channel
chr4_-_41503046 9.593 ENSMUST00000054920.4
AI464131
expressed sequence AI464131
chr4_-_133967893 9.575 ENSMUST00000100472.3
ENSMUST00000136327.1
Hmgn2

high mobility group nucleosomal binding domain 2

chr1_+_191098414 9.539 ENSMUST00000027943.4
Batf3
basic leucine zipper transcription factor, ATF-like 3
chr15_-_55090422 9.499 ENSMUST00000110231.1
ENSMUST00000023059.6
Dscc1

defective in sister chromatid cohesion 1 homolog (S. cerevisiae)

chr6_+_146888481 9.470 ENSMUST00000016631.7
ENSMUST00000111623.2
Ppfibp1

PTPRF interacting protein, binding protein 1 (liprin beta 1)

chr11_-_69948145 9.367 ENSMUST00000179298.1
ENSMUST00000018710.6
ENSMUST00000135437.1
ENSMUST00000141837.2
ENSMUST00000142500.1
Slc2a4




solute carrier family 2 (facilitated glucose transporter), member 4




chr15_-_76639840 9.334 ENSMUST00000166974.1
ENSMUST00000168185.1
Tonsl

tonsoku-like, DNA repair protein

chr1_-_172206684 9.326 ENSMUST00000155109.1
Pea15a
phosphoprotein enriched in astrocytes 15A
chr5_+_115845229 9.310 ENSMUST00000137952.1
ENSMUST00000148245.1
Cit

citron

chr2_-_180889660 9.271 ENSMUST00000137629.1
Gm14342
predicted gene 14342
chr1_-_181842334 9.233 ENSMUST00000005003.6
Lbr
lamin B receptor
chr4_+_115000174 9.197 ENSMUST00000129957.1
Stil
Scl/Tal1 interrupting locus
chr3_+_68869563 9.163 ENSMUST00000054551.2
1110032F04Rik
RIKEN cDNA 1110032F04 gene
chr5_-_138170992 9.158 ENSMUST00000139983.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr2_+_125247190 9.154 ENSMUST00000082122.7
Dut
deoxyuridine triphosphatase
chr2_-_34913976 9.142 ENSMUST00000028232.3
Phf19
PHD finger protein 19
chr4_-_95052188 9.135 ENSMUST00000107094.1
Jun
Jun oncogene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
19.2 57.5 GO:0061075 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
18.2 36.4 GO:0072180 mesonephric duct development(GO:0072177) mesonephric duct morphogenesis(GO:0072180)
17.0 68.0 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
14.6 43.7 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
14.5 43.4 GO:0014826 vein smooth muscle contraction(GO:0014826)
13.7 163.8 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
11.7 81.8 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
10.0 29.9 GO:0061144 alveolar secondary septum development(GO:0061144)
9.0 45.0 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
8.4 25.3 GO:0097402 neuroblast migration(GO:0097402)
8.0 40.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
8.0 40.0 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
7.9 15.7 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
7.7 30.6 GO:0007354 zygotic determination of anterior/posterior axis, embryo(GO:0007354)
6.8 20.3 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
6.5 19.5 GO:1901420 negative regulation of response to alcohol(GO:1901420)
6.5 19.4 GO:1904975 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
6.4 19.3 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
6.3 25.3 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
6.1 12.2 GO:0033864 positive regulation of NAD(P)H oxidase activity(GO:0033864)
6.0 90.4 GO:0010216 maintenance of DNA methylation(GO:0010216)
5.9 29.6 GO:0032298 positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
5.9 5.9 GO:0060423 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
5.9 58.6 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
5.8 28.8 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
5.7 39.7 GO:0098535 de novo centriole assembly(GO:0098535)
5.4 16.1 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
5.3 21.2 GO:0070829 heterochromatin maintenance(GO:0070829)
5.3 21.0 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
5.2 109.8 GO:0007530 sex determination(GO:0007530)
5.1 15.4 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
5.1 25.3 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
5.0 15.0 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
5.0 10.0 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
5.0 94.3 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
5.0 34.7 GO:1904177 regulation of adipose tissue development(GO:1904177)
4.9 14.8 GO:0030916 otic vesicle formation(GO:0030916)
4.9 24.7 GO:0015705 iodide transport(GO:0015705)
4.8 24.2 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
4.8 33.9 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
4.8 120.1 GO:0006270 DNA replication initiation(GO:0006270)
4.6 13.9 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
4.4 17.6 GO:0051311 spindle assembly involved in female meiosis(GO:0007056) meiotic metaphase plate congression(GO:0051311)
4.4 17.5 GO:0030091 protein repair(GO:0030091)
4.3 13.0 GO:0006166 purine ribonucleoside salvage(GO:0006166)
4.3 12.9 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
4.0 12.0 GO:0021759 globus pallidus development(GO:0021759)
4.0 35.7 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
3.9 7.8 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
3.8 15.3 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
3.8 19.1 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
3.8 11.4 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
3.8 22.8 GO:0033504 floor plate development(GO:0033504)
3.8 19.0 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
3.7 29.6 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
3.7 11.0 GO:0070634 transepithelial ammonium transport(GO:0070634)
3.6 10.7 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
3.5 63.6 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
3.5 7.0 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
3.4 6.9 GO:0010032 meiotic chromosome condensation(GO:0010032)
3.4 24.1 GO:0046060 dATP metabolic process(GO:0046060)
3.3 26.8 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
3.3 13.3 GO:0003360 brainstem development(GO:0003360)
3.3 9.9 GO:0042732 D-xylose metabolic process(GO:0042732)
3.3 9.9 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
3.3 3.3 GO:0072069 DCT cell differentiation(GO:0072069) metanephric DCT cell differentiation(GO:0072240)
3.3 6.5 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
3.2 3.2 GO:0046101 purine nucleobase biosynthetic process(GO:0009113) hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
3.2 6.5 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
3.1 9.2 GO:0032474 otolith morphogenesis(GO:0032474)
3.0 9.0 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
3.0 17.9 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
3.0 44.6 GO:0007076 mitotic chromosome condensation(GO:0007076)
3.0 11.8 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
2.9 14.7 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
2.9 34.9 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
2.9 8.6 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931) calcium-independent cell-matrix adhesion(GO:0007161) transforming growth factor-beta secretion(GO:0038044)
2.8 19.8 GO:0010273 detoxification of copper ion(GO:0010273) cellular response to zinc ion(GO:0071294) stress response to copper ion(GO:1990169)
2.8 8.3 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
2.8 8.3 GO:0045004 DNA replication proofreading(GO:0045004)
2.6 7.8 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
2.6 15.6 GO:0006348 chromatin silencing at telomere(GO:0006348)
2.6 15.4 GO:0021938 smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
2.5 17.6 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
2.4 29.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
2.4 7.2 GO:0007341 penetration of zona pellucida(GO:0007341)
2.4 21.6 GO:0001675 acrosome assembly(GO:0001675)
2.4 19.2 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
2.4 9.6 GO:0046112 nucleobase biosynthetic process(GO:0046112)
2.4 7.1 GO:0072757 cellular response to camptothecin(GO:0072757)
2.3 11.7 GO:0021905 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
2.3 7.0 GO:0002432 granuloma formation(GO:0002432)
2.3 9.3 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
2.3 11.6 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
2.3 9.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
2.3 25.1 GO:2000653 regulation of genetic imprinting(GO:2000653)
2.3 11.3 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
2.3 47.4 GO:0040034 regulation of development, heterochronic(GO:0040034)
2.2 6.6 GO:0002184 cytoplasmic translational termination(GO:0002184)
2.2 8.8 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
2.2 6.5 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
2.1 6.3 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
2.1 6.3 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978)
2.1 6.2 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
2.1 6.2 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
2.1 12.4 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
2.0 14.3 GO:0051660 establishment of centrosome localization(GO:0051660)
2.0 16.2 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
2.0 2.0 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
2.0 7.9 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
2.0 9.8 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
1.9 7.7 GO:0072675 osteoclast fusion(GO:0072675)
1.9 5.8 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
1.9 7.7 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
1.9 1.9 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
1.9 1.9 GO:0045716 low-density lipoprotein particle receptor biosynthetic process(GO:0045713) regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714) positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
1.9 3.7 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
1.8 20.1 GO:0042473 outer ear morphogenesis(GO:0042473)
1.8 3.6 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100) response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
1.8 12.5 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
1.8 12.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
1.8 5.3 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
1.7 31.3 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
1.7 5.2 GO:0051316 attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation(GO:0051316)
1.7 16.6 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
1.6 17.9 GO:0033260 nuclear DNA replication(GO:0033260)
1.6 12.8 GO:0006004 fucose metabolic process(GO:0006004)
1.6 20.8 GO:0043252 sodium-independent organic anion transport(GO:0043252)
1.6 4.7 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
1.6 7.8 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
1.6 12.5 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
1.6 7.8 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
1.5 1.5 GO:2000047 regulation of cell-cell adhesion mediated by cadherin(GO:2000047)
1.5 3.0 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
1.5 7.6 GO:0031860 telomeric 3' overhang formation(GO:0031860)
1.5 4.5 GO:0006597 spermine biosynthetic process(GO:0006597)
1.5 4.5 GO:0097350 neutrophil clearance(GO:0097350)
1.5 4.5 GO:0033566 gamma-tubulin complex localization(GO:0033566)
1.5 1.5 GO:1903294 regulation of glutamate secretion, neurotransmission(GO:1903294) positive regulation of glutamate secretion, neurotransmission(GO:1903296)
1.5 2.9 GO:0006273 lagging strand elongation(GO:0006273)
1.5 2.9 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
1.4 4.3 GO:0019441 tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218) kynurenine metabolic process(GO:0070189)
1.4 5.7 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
1.4 4.3 GO:1904154 protein localization to endoplasmic reticulum exit site(GO:0070973) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
1.4 1.4 GO:1905066 regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of heart induction(GO:1901321) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
1.4 8.3 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
1.4 4.1 GO:0070889 platelet alpha granule organization(GO:0070889) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162)
1.4 8.2 GO:0090005 negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
1.4 4.1 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
1.4 16.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
1.3 8.0 GO:0044351 cleavage furrow formation(GO:0036089) macropinocytosis(GO:0044351)
1.3 18.3 GO:0032098 regulation of appetite(GO:0032098)
1.3 10.3 GO:0033327 Leydig cell differentiation(GO:0033327)
1.3 10.2 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
1.3 3.8 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
1.3 6.3 GO:0060161 positive regulation of dopamine receptor signaling pathway(GO:0060161)
1.3 17.5 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
1.2 3.7 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
1.2 24.9 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
1.2 5.0 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
1.2 4.9 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
1.2 8.6 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
1.2 10.9 GO:0045048 protein insertion into ER membrane(GO:0045048)
1.2 6.0 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
1.2 2.4 GO:1902869 regulation of amacrine cell differentiation(GO:1902869)
1.2 3.6 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
1.2 57.9 GO:0035019 somatic stem cell population maintenance(GO:0035019)
1.2 14.1 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
1.1 4.6 GO:0009414 response to water deprivation(GO:0009414)
1.1 52.7 GO:0051310 metaphase plate congression(GO:0051310)
1.1 5.7 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
1.1 4.6 GO:2000319 negative regulation of T-helper 17 type immune response(GO:2000317) regulation of T-helper 17 cell differentiation(GO:2000319) negative regulation of T-helper 17 cell differentiation(GO:2000320)
1.1 5.6 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
1.1 26.0 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
1.1 9.0 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
1.1 7.8 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
1.1 2.2 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
1.1 5.5 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
1.1 4.4 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
1.1 1.1 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
1.1 3.3 GO:0042275 error-free postreplication DNA repair(GO:0042275)
1.1 2.2 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
1.1 3.2 GO:0001787 natural killer cell proliferation(GO:0001787)
1.0 3.1 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512)
1.0 5.1 GO:1903527 regulation of membrane tubulation(GO:1903525) positive regulation of membrane tubulation(GO:1903527)
1.0 13.3 GO:0019985 translesion synthesis(GO:0019985)
1.0 6.1 GO:0016584 nucleosome positioning(GO:0016584)
1.0 28.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
1.0 1.0 GO:1903416 response to glycoside(GO:1903416)
1.0 2.0 GO:0070459 prolactin secretion(GO:0070459)
1.0 5.0 GO:0072697 protein localization to cell cortex(GO:0072697)
1.0 8.0 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
1.0 8.0 GO:0060430 lung saccule development(GO:0060430)
1.0 1.0 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
1.0 10.9 GO:0031935 regulation of chromatin silencing(GO:0031935)
1.0 10.9 GO:0030903 notochord development(GO:0030903)
1.0 7.7 GO:0048537 mucosal-associated lymphoid tissue development(GO:0048537) Peyer's patch development(GO:0048541)
1.0 6.7 GO:0019336 phenol-containing compound catabolic process(GO:0019336)
1.0 8.6 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.9 3.8 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.9 14.2 GO:0030261 chromosome condensation(GO:0030261)
0.9 15.8 GO:0034508 centromere complex assembly(GO:0034508)
0.9 11.2 GO:0036297 interstrand cross-link repair(GO:0036297)
0.9 9.2 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.9 2.7 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.9 7.2 GO:0051571 positive regulation of histone H3-K4 methylation(GO:0051571)
0.9 25.2 GO:0003416 endochondral bone growth(GO:0003416)
0.9 2.7 GO:0048496 maintenance of organ identity(GO:0048496)
0.9 11.6 GO:2001212 regulation of vasculogenesis(GO:2001212)
0.9 3.5 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.9 5.2 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.9 1.7 GO:0032776 DNA methylation on cytosine within a CG sequence(GO:0010424) DNA methylation on cytosine(GO:0032776)
0.9 5.2 GO:0097421 liver regeneration(GO:0097421)
0.9 2.6 GO:0051026 chiasma assembly(GO:0051026)
0.9 13.7 GO:0034389 lipid particle organization(GO:0034389)
0.9 14.5 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.9 1.7 GO:0097360 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.8 20.4 GO:0046325 negative regulation of glucose import(GO:0046325)
0.8 2.5 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.8 8.3 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.8 2.4 GO:0010957 negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137) Notch signaling involved in heart development(GO:0061314)
0.8 2.3 GO:0061743 motor learning(GO:0061743)
0.8 1.6 GO:0009814 defense response, incompatible interaction(GO:0009814)
0.8 3.9 GO:0035878 nail development(GO:0035878)
0.8 1.6 GO:0070365 hepatocyte differentiation(GO:0070365)
0.8 3.1 GO:0001887 selenium compound metabolic process(GO:0001887) selenocysteine metabolic process(GO:0016259)
0.8 2.3 GO:1903334 positive regulation of protein folding(GO:1903334)
0.8 3.0 GO:0090209 negative regulation of triglyceride metabolic process(GO:0090209)
0.8 8.3 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.7 2.2 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.7 3.0 GO:0002667 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.7 3.7 GO:0006543 glutamine catabolic process(GO:0006543)
0.7 12.4 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.7 25.3 GO:0046677 response to antibiotic(GO:0046677)
0.7 2.2 GO:0019043 establishment of viral latency(GO:0019043)
0.7 13.0 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.7 34.0 GO:0071277 cellular response to calcium ion(GO:0071277)
0.7 7.1 GO:0006907 pinocytosis(GO:0006907)
0.7 8.5 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.7 11.9 GO:1904816 positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.7 7.4 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.7 5.3 GO:0001842 neural fold formation(GO:0001842)
0.7 25.4 GO:0090307 mitotic spindle assembly(GO:0090307)
0.7 4.0 GO:0051503 adenine nucleotide transport(GO:0051503)
0.6 1.9 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.6 3.2 GO:1904690 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.6 3.8 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.6 18.4 GO:0018345 protein palmitoylation(GO:0018345)
0.6 36.0 GO:0006342 chromatin silencing(GO:0006342)
0.6 4.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.6 2.5 GO:0000212 meiotic spindle organization(GO:0000212)
0.6 7.3 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.6 6.1 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.6 11.5 GO:0031297 replication fork processing(GO:0031297)
0.6 3.6 GO:1902373 negative regulation of mRNA catabolic process(GO:1902373)
0.6 8.8 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.6 5.3 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.6 1.7 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.6 1.7 GO:0009146 purine nucleoside triphosphate catabolic process(GO:0009146)
0.6 1.7 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.6 4.6 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.6 1.1 GO:0019401 alditol biosynthetic process(GO:0019401)
0.6 11.6 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.6 2.8 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.5 5.4 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.5 2.2 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.5 4.3 GO:0046599 regulation of centriole replication(GO:0046599)
0.5 4.9 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.5 14.4 GO:0051225 spindle assembly(GO:0051225)
0.5 15.7 GO:0006284 base-excision repair(GO:0006284)
0.5 11.9 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.5 2.1 GO:0046294 formaldehyde catabolic process(GO:0046294)
0.5 3.0 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.5 10.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.5 10.0 GO:0008340 determination of adult lifespan(GO:0008340)
0.5 2.5 GO:0097503 sialylation(GO:0097503)
0.5 6.4 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.5 4.4 GO:0032682 negative regulation of chemokine production(GO:0032682)
0.5 9.7 GO:0052646 alditol phosphate metabolic process(GO:0052646)
0.5 5.1 GO:0030224 monocyte differentiation(GO:0030224)
0.5 2.8 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.4 4.4 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.4 4.8 GO:0018065 protein-cofactor linkage(GO:0018065)
0.4 0.8 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.4 2.5 GO:0060510 Type II pneumocyte differentiation(GO:0060510)
0.4 3.8 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.4 1.2 GO:0001828 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.4 1.7 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.4 7.9 GO:0033687 osteoblast proliferation(GO:0033687)
0.4 0.8 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.4 4.5 GO:0031639 plasminogen activation(GO:0031639)
0.4 1.6 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.4 3.2 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.4 2.4 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.4 5.2 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.4 1.2 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.4 1.2 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.4 4.4 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.4 6.7 GO:0071451 cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451)
0.4 7.5 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.4 2.7 GO:0097237 cellular response to toxic substance(GO:0097237)
0.4 3.5 GO:0007440 foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)
0.4 0.8 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.4 1.2 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.4 3.4 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.4 3.4 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.4 3.0 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.4 5.2 GO:0048546 digestive tract morphogenesis(GO:0048546)
0.4 6.6 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.4 2.9 GO:0006020 inositol metabolic process(GO:0006020)
0.4 8.1 GO:0097062 dendritic spine maintenance(GO:0097062)
0.3 7.7 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.3 4.2 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.3 1.4 GO:0042256 mature ribosome assembly(GO:0042256)
0.3 1.7 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.3 2.0 GO:0006741 NADP biosynthetic process(GO:0006741)
0.3 1.7 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.3 5.0 GO:0006825 copper ion transport(GO:0006825)
0.3 3.0 GO:0007130 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.3 1.7 GO:0019236 response to pheromone(GO:0019236)
0.3 5.3 GO:0002052 positive regulation of neuroblast proliferation(GO:0002052)
0.3 3.3 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.3 13.6 GO:0035307 positive regulation of protein dephosphorylation(GO:0035307)
0.3 2.9 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.3 4.8 GO:0033622 integrin activation(GO:0033622)
0.3 1.9 GO:0031034 myosin filament assembly(GO:0031034)
0.3 13.2 GO:0032835 glomerulus development(GO:0032835)
0.3 2.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.3 5.0 GO:0001709 cell fate determination(GO:0001709)
0.3 2.5 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.3 14.7 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.3 1.2 GO:1903286 regulation of potassium ion import(GO:1903286)
0.3 5.1 GO:0044381 glucose import in response to insulin stimulus(GO:0044381)
0.3 44.1 GO:0006260 DNA replication(GO:0006260)
0.3 12.8 GO:0015914 phospholipid transport(GO:0015914)
0.3 0.3 GO:0034140 negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
0.3 1.1 GO:1990928 response to amino acid starvation(GO:1990928)
0.3 1.7 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.3 9.3 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.3 0.8 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.3 1.4 GO:0089700 protein kinase D signaling(GO:0089700)
0.3 0.5 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.3 1.6 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.3 3.7 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.3 1.1 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.3 3.9 GO:0043248 proteasome assembly(GO:0043248)
0.3 19.3 GO:0042472 inner ear morphogenesis(GO:0042472)
0.3 1.5 GO:0072081 proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081) specification of loop of Henle identity(GO:0072086)
0.3 1.8 GO:0035372 protein localization to microtubule(GO:0035372)
0.2 10.5 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.2 0.7 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.2 1.7 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.2 1.2 GO:1903232 melanosome assembly(GO:1903232)
0.2 0.7 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.2 2.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.2 6.9 GO:0006783 heme biosynthetic process(GO:0006783)
0.2 18.3 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.2 0.9 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.2 1.1 GO:0060768 epithelial cell proliferation involved in prostate gland development(GO:0060767) regulation of epithelial cell proliferation involved in prostate gland development(GO:0060768) negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.2 6.7 GO:0006405 RNA export from nucleus(GO:0006405)
0.2 2.3 GO:0034982 mitochondrial protein processing(GO:0034982)
0.2 4.5 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.2 1.8 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.2 8.1 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.2 0.8 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.2 7.4 GO:2001022 positive regulation of response to DNA damage stimulus(GO:2001022)
0.2 7.9 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.2 15.6 GO:0006413 translational initiation(GO:0006413)
0.2 3.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 1.5 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.2 1.9 GO:0001819 positive regulation of cytokine production(GO:0001819)
0.2 0.6 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.2 0.6 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.2 4.4 GO:0006289 nucleotide-excision repair(GO:0006289)
0.2 0.7 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.2 1.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 1.8 GO:0006817 phosphate ion transport(GO:0006817)
0.2 1.6 GO:0045794 negative regulation of cell volume(GO:0045794)
0.2 1.2 GO:0035272 exocrine system development(GO:0035272)
0.2 2.6 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
0.2 2.4 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.2 2.0 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.2 21.7 GO:0043524 negative regulation of neuron apoptotic process(GO:0043524)
0.2 5.0 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.2 6.7 GO:0016925 protein sumoylation(GO:0016925)
0.2 1.2 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.2 0.6 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553) Golgi reassembly(GO:0090168)
0.2 10.0 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.2 0.2 GO:0071224 cellular response to peptidoglycan(GO:0071224)
0.2 3.6 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 1.5 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 1.3 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.1 1.0 GO:1903301 fructose 2,6-bisphosphate metabolic process(GO:0006003) regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)
0.1 8.6 GO:0031497 chromatin assembly(GO:0031497)
0.1 0.3 GO:0010835 regulation of protein ADP-ribosylation(GO:0010835)
0.1 2.4 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.1 1.6 GO:0006415 translational termination(GO:0006415)
0.1 0.7 GO:0014029 neural crest formation(GO:0014029)
0.1 2.5 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 4.3 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.3 GO:0046655 folic acid metabolic process(GO:0046655)
0.1 0.1 GO:0090135 actin filament branching(GO:0090135) negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 1.5 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.1 0.9 GO:0055012 ventricular cardiac muscle cell differentiation(GO:0055012)
0.1 0.4 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 2.8 GO:1904894 positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.1 1.0 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 0.2 GO:1901724 positive regulation of cell proliferation involved in kidney development(GO:1901724)
0.1 4.0 GO:0016126 sterol biosynthetic process(GO:0016126)
0.1 0.7 GO:0034227 tRNA thio-modification(GO:0034227)
0.1 1.6 GO:0043488 regulation of mRNA stability(GO:0043488)
0.1 0.2 GO:0031440 regulation of mRNA 3'-end processing(GO:0031440)
0.1 0.7 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.1 0.2 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.1 5.0 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1 2.0 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 1.4 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.4 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.6 GO:0006337 nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986)
0.1 2.1 GO:0000154 rRNA modification(GO:0000154)
0.1 1.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 6.3 GO:0000910 cytokinesis(GO:0000910)
0.1 0.5 GO:0045792 negative regulation of cell size(GO:0045792)
0.1 0.3 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.1 9.0 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.1 2.0 GO:0007588 excretion(GO:0007588)
0.1 1.0 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.1 0.4 GO:0046950 cellular ketone body metabolic process(GO:0046950)
0.1 0.7 GO:0071539 protein localization to centrosome(GO:0071539)
0.1 3.3 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 0.2 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.1 0.2 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) lateral motor column neuron migration(GO:0097477)
0.1 0.5 GO:0019835 cytolysis(GO:0019835)
0.1 0.4 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.1 0.6 GO:0035315 hair cell differentiation(GO:0035315) auditory receptor cell differentiation(GO:0042491)
0.1 0.2 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.1 1.5 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 0.2 GO:0070166 enamel mineralization(GO:0070166)
0.1 0.6 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 0.2 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.7 GO:0000338 protein deneddylation(GO:0000338)
0.0 1.0 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.7 GO:0035329 hippo signaling(GO:0035329)
0.0 1.1 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.0 1.1 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.8 GO:0060135 maternal process involved in female pregnancy(GO:0060135)
0.0 0.6 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0 0.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.3 GO:0071774 response to fibroblast growth factor(GO:0071774)
0.0 0.9 GO:0042775 mitochondrial ATP synthesis coupled electron transport(GO:0042775)
0.0 1.3 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.3 GO:0071222 cellular response to lipopolysaccharide(GO:0071222)
0.0 0.3 GO:0071897 DNA biosynthetic process(GO:0071897)
0.0 1.0 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.1 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.0 0.6 GO:0007492 endoderm development(GO:0007492)
0.0 2.5 GO:0030217 T cell differentiation(GO:0030217)
0.0 1.9 GO:0007623 circadian rhythm(GO:0007623)
0.0 0.4 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 1.1 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.3 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.8 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.0 0.4 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)
0.0 0.1 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.3 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.6 GO:2001237 negative regulation of extrinsic apoptotic signaling pathway(GO:2001237)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
13.2 39.6 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
12.6 151.5 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
10.4 31.3 GO:0033186 CAF-1 complex(GO:0033186)
10.3 51.4 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
9.1 136.8 GO:0042555 MCM complex(GO:0042555)
6.6 26.5 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
6.3 37.7 GO:0098536 deuterosome(GO:0098536)
5.5 16.5 GO:1990423 RZZ complex(GO:1990423)
5.5 16.5 GO:0000801 central element(GO:0000801)
5.4 27.0 GO:0031523 Myb complex(GO:0031523)
5.1 51.4 GO:0000796 condensin complex(GO:0000796)
5.0 29.9 GO:0005663 DNA replication factor C complex(GO:0005663)
4.4 13.3 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
4.3 26.0 GO:0035976 AP1 complex(GO:0035976)
4.2 21.0 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
4.1 12.3 GO:0071149 TEAD-2-YAP complex(GO:0071149)
4.0 12.1 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
4.0 7.9 GO:0071953 elastic fiber(GO:0071953)
3.5 7.0 GO:0036488 CHOP-C/EBP complex(GO:0036488)
3.3 9.8 GO:0099573 glutamatergic postsynaptic density(GO:0099573)
3.2 22.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
3.1 15.7 GO:0097149 centralspindlin complex(GO:0097149)
3.1 100.7 GO:0000788 nuclear nucleosome(GO:0000788)
3.0 15.2 GO:0001740 Barr body(GO:0001740)
3.0 9.0 GO:0071914 prominosome(GO:0071914)
2.9 8.6 GO:0005577 fibrinogen complex(GO:0005577)
2.9 8.6 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
2.8 11.3 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
2.8 8.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
2.6 5.2 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
2.5 15.1 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
2.4 12.2 GO:0043020 NADPH oxidase complex(GO:0043020)
2.3 2.3 GO:0044301 climbing fiber(GO:0044301)
2.3 11.3 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
2.2 11.1 GO:0097226 sperm mitochondrial sheath(GO:0097226)
2.2 6.6 GO:0018444 translation release factor complex(GO:0018444)
2.2 8.7 GO:0005606 laminin-1 complex(GO:0005606)
2.1 10.6 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
2.0 116.8 GO:0005657 replication fork(GO:0005657)
2.0 17.6 GO:0072687 meiotic spindle(GO:0072687)
1.9 38.9 GO:0035098 ESC/E(Z) complex(GO:0035098)
1.9 40.1 GO:0044300 cerebellar mossy fiber(GO:0044300)
1.9 20.6 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
1.8 31.3 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
1.8 69.5 GO:0060077 inhibitory synapse(GO:0060077)
1.8 7.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
1.7 6.9 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
1.7 5.2 GO:0031510 SUMO activating enzyme complex(GO:0031510)
1.7 13.7 GO:0070652 HAUS complex(GO:0070652)
1.7 55.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
1.7 10.0 GO:0044530 supraspliceosomal complex(GO:0044530)
1.6 22.6 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
1.5 4.6 GO:1990075 stereocilia ankle link complex(GO:0002142) periciliary membrane compartment(GO:1990075)
1.5 4.6 GO:0005673 transcription factor TFIIE complex(GO:0005673)
1.5 25.1 GO:0005652 nuclear lamina(GO:0005652)
1.3 9.3 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
1.3 6.6 GO:0005688 U6 snRNP(GO:0005688)
1.3 10.6 GO:0031415 NatA complex(GO:0031415)
1.3 11.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
1.2 4.9 GO:0033553 rDNA heterochromatin(GO:0033553)
1.2 8.5 GO:0097422 tubular endosome(GO:0097422)
1.2 11.9 GO:0097431 mitotic spindle pole(GO:0097431)
1.2 4.7 GO:0008623 CHRAC(GO:0008623)
1.2 13.9 GO:0016600 flotillin complex(GO:0016600)
1.1 5.7 GO:0033010 paranodal junction(GO:0033010)
1.1 7.9 GO:0097452 GAIT complex(GO:0097452)
1.1 5.6 GO:0005828 kinetochore microtubule(GO:0005828)
1.1 4.4 GO:0000444 MIS12/MIND type complex(GO:0000444)
1.1 24.7 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
1.1 4.3 GO:0030121 AP-1 adaptor complex(GO:0030121)
1.0 5.2 GO:0072487 MSL complex(GO:0072487)
1.0 5.1 GO:0001652 granular component(GO:0001652)
1.0 4.0 GO:0030289 protein phosphatase 4 complex(GO:0030289)
1.0 6.8 GO:0030915 Smc5-Smc6 complex(GO:0030915)
1.0 9.6 GO:0034709 methylosome(GO:0034709)
0.9 15.2 GO:0044453 nuclear membrane part(GO:0044453)
0.9 9.1 GO:0030057 desmosome(GO:0030057)
0.9 2.7 GO:0097543 ciliary inversin compartment(GO:0097543)
0.9 7.9 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.9 5.2 GO:0000938 GARP complex(GO:0000938)
0.9 4.3 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.8 5.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.8 5.9 GO:0097165 nuclear stress granule(GO:0097165)
0.8 40.1 GO:0031519 PcG protein complex(GO:0031519)
0.8 5.0 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.8 4.9 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.8 2.5 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.8 3.2 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.8 6.4 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.8 22.2 GO:0051233 spindle midzone(GO:0051233)
0.7 8.2 GO:0097542 ciliary tip(GO:0097542)
0.7 9.6 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.7 11.0 GO:1904115 axon cytoplasm(GO:1904115)
0.7 67.9 GO:0005814 centriole(GO:0005814)
0.6 35.1 GO:0005882 intermediate filament(GO:0005882)
0.6 4.5 GO:0002177 manchette(GO:0002177)
0.6 3.7 GO:0070531 BRCA1-A complex(GO:0070531)
0.6 4.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.6 6.8 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.6 21.1 GO:0034707 chloride channel complex(GO:0034707)
0.6 4.1 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.6 2.3 GO:0005745 m-AAA complex(GO:0005745)
0.6 2.3 GO:0032021 NELF complex(GO:0032021)
0.6 9.2 GO:0030008 TRAPP complex(GO:0030008)
0.6 1.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.5 7.9 GO:0045120 pronucleus(GO:0045120)
0.5 26.7 GO:0009925 basal plasma membrane(GO:0009925)
0.5 2.6 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.5 1.0 GO:0031931 TORC1 complex(GO:0031931)
0.5 5.6 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.5 5.1 GO:0097526 U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.5 4.4 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.5 2.5 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.5 34.6 GO:0005844 polysome(GO:0005844)
0.5 3.4 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.5 10.9 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.5 20.8 GO:0043034 costamere(GO:0043034)
0.5 76.2 GO:0000775 chromosome, centromeric region(GO:0000775)
0.4 21.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.4 5.3 GO:0044294 dendritic growth cone(GO:0044294)
0.4 3.0 GO:0042824 MHC class I peptide loading complex(GO:0042824) TAP complex(GO:0042825)
0.4 2.1 GO:0070876 SOSS complex(GO:0070876)
0.4 3.4 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.4 1.7 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.4 3.8 GO:0000974 Prp19 complex(GO:0000974)
0.4 11.1 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.4 3.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.4 1.2 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.4 3.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.4 14.0 GO:0002102 podosome(GO:0002102)
0.4 4.1 GO:0030014 CCR4-NOT complex(GO:0030014)
0.4 22.8 GO:0000793 condensed chromosome(GO:0000793)
0.4 2.9 GO:0090543 Flemming body(GO:0090543)
0.4 5.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.4 4.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.4 8.0 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.4 30.4 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.3 1.0 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.3 3.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.3 9.8 GO:0035869 ciliary transition zone(GO:0035869)
0.3 1.6 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.3 2.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.3 120.1 GO:0000228 nuclear chromosome(GO:0000228)
0.3 1.2 GO:0042827 platelet dense granule(GO:0042827)
0.3 26.5 GO:0005681 spliceosomal complex(GO:0005681)
0.3 3.9 GO:0005922 connexon complex(GO:0005922)
0.3 4.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.3 7.9 GO:0016592 mediator complex(GO:0016592)
0.3 10.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.3 1.1 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.3 2.3 GO:0045252 dihydrolipoyl dehydrogenase complex(GO:0045240) oxoglutarate dehydrogenase complex(GO:0045252)
0.3 1.6 GO:0000125 PCAF complex(GO:0000125)
0.3 3.1 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.2 3.2 GO:0090544 BAF-type complex(GO:0090544)
0.2 13.4 GO:0031526 brush border membrane(GO:0031526)
0.2 3.9 GO:0031083 BLOC-1 complex(GO:0031083)
0.2 1.9 GO:0005787 signal peptidase complex(GO:0005787)
0.2 2.4 GO:0045298 tubulin complex(GO:0045298)
0.2 1.4 GO:0005859 muscle myosin complex(GO:0005859)
0.2 1.9 GO:0000815 ESCRT III complex(GO:0000815)
0.2 16.6 GO:0031225 anchored component of membrane(GO:0031225)
0.2 8.8 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.2 11.4 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 0.7 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.2 39.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.2 1.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 2.9 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.2 1.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.2 7.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 1.0 GO:0097255 R2TP complex(GO:0097255)
0.2 20.5 GO:0043195 terminal bouton(GO:0043195)
0.2 7.3 GO:0016235 aggresome(GO:0016235)
0.2 34.9 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.2 1.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.2 1.6 GO:0061574 ASAP complex(GO:0061574)
0.2 17.0 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.2 61.8 GO:0009986 cell surface(GO:0009986)
0.2 1.1 GO:0097470 ribbon synapse(GO:0097470)
0.2 11.3 GO:0000502 proteasome complex(GO:0000502)
0.2 1.5 GO:0016272 prefoldin complex(GO:0016272)
0.2 8.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.2 4.8 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.2 9.9 GO:0036064 ciliary basal body(GO:0036064)
0.2 7.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.2 20.2 GO:0001650 fibrillar center(GO:0001650)
0.2 3.9 GO:0005876 spindle microtubule(GO:0005876)
0.1 8.1 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 0.6 GO:0031501 mannosyltransferase complex(GO:0031501)
0.1 1.7 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 4.1 GO:0014704 intercalated disc(GO:0014704)
0.1 1.7 GO:0030673 axolemma(GO:0030673)
0.1 7.7 GO:0044391 ribosomal subunit(GO:0044391)
0.1 22.2 GO:0005667 transcription factor complex(GO:0005667)
0.1 0.7 GO:0071986 Ragulator complex(GO:0071986)
0.1 2.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.3 GO:0045171 intercellular bridge(GO:0045171)
0.1 1.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 4.4 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 1.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 2.0 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 3.6 GO:0043198 dendritic shaft(GO:0043198)
0.1 6.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 0.9 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.9 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 0.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 412.0 GO:0005634 nucleus(GO:0005634)
0.1 2.0 GO:0016459 myosin complex(GO:0016459)
0.0 0.2 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.4 GO:0005811 lipid particle(GO:0005811)
0.0 1.3 GO:0043209 myelin sheath(GO:0043209)
0.0 0.2 GO:0005832 zona pellucida receptor complex(GO:0002199) chaperonin-containing T-complex(GO:0005832)
0.0 5.7 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 1.9 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 1.6 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 1.9 GO:0043235 receptor complex(GO:0043235)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
30.4 151.9 GO:0042289 MHC class II protein binding(GO:0042289)
18.6 74.4 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
15.0 60.0 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
13.7 41.0 GO:0004962 endothelin receptor activity(GO:0004962)
11.3 79.4 GO:0004351 glutamate decarboxylase activity(GO:0004351)
10.3 51.4 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
8.7 26.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
7.7 30.8 GO:0004035 alkaline phosphatase activity(GO:0004035)
7.2 7.2 GO:0015616 DNA translocase activity(GO:0015616)
6.2 24.7 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
5.5 27.3 GO:0043515 kinetochore binding(GO:0043515)
5.2 31.3 GO:0010997 anaphase-promoting complex binding(GO:0010997)
5.0 15.0 GO:0070052 collagen V binding(GO:0070052)
4.3 25.8 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
4.2 37.6 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
4.1 12.4 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
3.8 15.3 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
3.8 30.5 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
3.7 18.5 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
3.7 40.5 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
3.5 7.0 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
3.3 10.0 GO:0051870 methotrexate binding(GO:0051870)
3.2 119.8 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
3.2 12.8 GO:0042806 fucose binding(GO:0042806)
3.0 12.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
3.0 17.8 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
2.9 96.4 GO:0070412 R-SMAD binding(GO:0070412)
2.9 46.6 GO:0003680 AT DNA binding(GO:0003680)
2.6 7.9 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
2.5 9.9 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
2.4 9.6 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
2.4 16.6 GO:0015198 oligopeptide transporter activity(GO:0015198)
2.4 19.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
2.4 28.3 GO:0035173 histone kinase activity(GO:0035173)
2.3 25.7 GO:0048406 nerve growth factor binding(GO:0048406)
2.3 15.8 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
2.2 13.3 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
2.2 11.0 GO:0017108 5'-flap endonuclease activity(GO:0017108)
2.2 13.1 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
2.2 6.5 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
2.2 6.5 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
2.1 12.4 GO:0001069 regulatory region RNA binding(GO:0001069)
2.1 6.2 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
2.0 6.1 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
2.0 18.0 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
2.0 8.0 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
1.9 7.8 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
1.9 9.6 GO:0047134 protein-disulfide reductase activity(GO:0047134)
1.9 100.2 GO:0003678 DNA helicase activity(GO:0003678)
1.8 7.2 GO:0005113 patched binding(GO:0005113)
1.6 4.9 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
1.6 11.3 GO:0000150 recombinase activity(GO:0000150)
1.6 23.8 GO:0032552 deoxyribonucleotide binding(GO:0032552)
1.6 12.7 GO:0070087 chromo shadow domain binding(GO:0070087)
1.5 12.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
1.5 6.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
1.5 6.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
1.5 30.1 GO:0071855 neuropeptide receptor binding(GO:0071855)
1.5 28.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
1.5 16.2 GO:0043522 leucine zipper domain binding(GO:0043522)
1.5 5.8 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
1.4 8.6 GO:0045340 mercury ion binding(GO:0045340)
1.4 8.6 GO:0070883 pre-miRNA binding(GO:0070883)
1.4 32.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
1.4 6.8 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
1.3 48.4 GO:0017025 TBP-class protein binding(GO:0017025)
1.3 4.0 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
1.3 6.6 GO:0030621 U4 snRNA binding(GO:0030621)
1.3 5.2 GO:0036468 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
1.3 1.3 GO:0050436 microfibril binding(GO:0050436)
1.3 31.2 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
1.3 25.9 GO:0001222 transcription corepressor binding(GO:0001222)
1.3 7.7 GO:0070644 vitamin D response element binding(GO:0070644)
1.3 7.6 GO:0008494 translation activator activity(GO:0008494)
1.2 19.9 GO:0030957 Tat protein binding(GO:0030957)
1.2 8.5 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
1.2 4.8 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
1.2 2.4 GO:0000405 bubble DNA binding(GO:0000405)
1.1 4.5 GO:0019808 polyamine binding(GO:0019808)
1.1 2.3 GO:0019966 interleukin-1 binding(GO:0019966)
1.1 11.1 GO:0004017 adenylate kinase activity(GO:0004017)
1.1 1.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
1.1 8.8 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
1.1 6.5 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
1.1 8.7 GO:0043208 glycosphingolipid binding(GO:0043208)
1.1 3.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
1.1 5.3 GO:0045545 syndecan binding(GO:0045545)
1.1 11.6 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
1.0 17.8 GO:0042056 chemoattractant activity(GO:0042056)
1.0 8.3 GO:0008395 steroid hydroxylase activity(GO:0008395)
1.0 4.1 GO:0016842 amidine-lyase activity(GO:0016842)
1.0 220.2 GO:0042393 histone binding(GO:0042393)
1.0 7.1 GO:0034452 dynactin binding(GO:0034452)
1.0 3.0 GO:0009041 uridylate kinase activity(GO:0009041)
1.0 7.8 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.9 8.5 GO:0050692 DBD domain binding(GO:0050692)
0.9 7.5 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.9 4.6 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.9 2.7 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.9 18.0 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.9 9.0 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.9 9.8 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.9 7.1 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.9 20.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.9 5.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.9 0.9 GO:0042296 ISG15 transferase activity(GO:0042296)
0.8 16.1 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.8 15.1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.8 13.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.8 3.3 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.8 3.3 GO:1990715 mRNA CDS binding(GO:1990715)
0.8 4.9 GO:0000213 tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.8 2.5 GO:0016901 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.8 3.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.8 7.3 GO:0003993 acid phosphatase activity(GO:0003993)
0.8 11.2 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.8 10.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.8 18.0 GO:0017160 Ral GTPase binding(GO:0017160)
0.8 3.9 GO:0038132 neuregulin binding(GO:0038132)
0.8 3.1 GO:0070279 vitamin B6 binding(GO:0070279)
0.8 28.3 GO:0008536 Ran GTPase binding(GO:0008536)
0.7 14.8 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.7 5.9 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.7 4.4 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.7 2.9 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.7 3.6 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.7 2.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.7 2.8 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700)
0.7 25.8 GO:0005507 copper ion binding(GO:0005507)
0.7 2.1 GO:0018738 S-formylglutathione hydrolase activity(GO:0018738)
0.7 8.9 GO:1990459 transferrin receptor binding(GO:1990459)
0.7 66.5 GO:0004386 helicase activity(GO:0004386)
0.7 2.0 GO:0003696 satellite DNA binding(GO:0003696)
0.7 16.9 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.6 1.9 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters(GO:0016894)
0.6 18.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.6 3.7 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.6 62.1 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.6 1.8 GO:0005436 sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319)
0.6 4.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.6 2.9 GO:0051425 PTB domain binding(GO:0051425)
0.6 1.7 GO:0042895 antibiotic transporter activity(GO:0042895)
0.6 1.2 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.6 13.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.6 3.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.6 4.5 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.6 25.4 GO:0070063 RNA polymerase binding(GO:0070063)
0.6 41.6 GO:0003697 single-stranded DNA binding(GO:0003697)
0.6 12.9 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.5 2.2 GO:0046923 ER retention sequence binding(GO:0046923)
0.5 7.0 GO:0008327 methyl-CpG binding(GO:0008327)
0.5 83.3 GO:0001047 core promoter binding(GO:0001047)
0.5 1.1 GO:0035877 death effector domain binding(GO:0035877)
0.5 8.9 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.5 1.5 GO:0019153 protein-disulfide reductase (glutathione) activity(GO:0019153)
0.5 5.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.5 12.0 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.5 17.3 GO:0031490 chromatin DNA binding(GO:0031490)
0.5 1.4 GO:0048019 receptor antagonist activity(GO:0048019)
0.5 7.4 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.5 2.3 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.5 16.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.4 4.4 GO:0015266 protein channel activity(GO:0015266)
0.4 2.2 GO:0043237 laminin-1 binding(GO:0043237)
0.4 1.7 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.4 6.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.4 5.1 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.4 8.0 GO:0001056 RNA polymerase III activity(GO:0001056)
0.4 3.9 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.4 6.3 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.4 9.9 GO:0031369 translation initiation factor binding(GO:0031369)
0.4 3.0 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.4 21.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.4 6.3 GO:0042805 actinin binding(GO:0042805)
0.4 1.5 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.4 2.9 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.4 8.3 GO:0043274 phospholipase binding(GO:0043274)
0.4 5.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.3 0.7 GO:0046978 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.3 4.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.3 4.3 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.3 2.3 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.3 1.0 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.3 20.7 GO:0005080 protein kinase C binding(GO:0005080)
0.3 6.4 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.3 2.9 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.3 1.6 GO:1990188 euchromatin binding(GO:1990188)
0.3 2.5 GO:0000400 four-way junction DNA binding(GO:0000400)
0.3 8.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.3 3.8 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.3 11.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.3 8.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.3 4.9 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.3 10.9 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.3 1.1 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.3 3.9 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.3 6.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.2 11.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.2 5.5 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.2 1.7 GO:0050815 phosphoserine binding(GO:0050815)
0.2 4.5 GO:0030544 Hsp70 protein binding(GO:0030544)
0.2 3.5 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.2 11.9 GO:0002039 p53 binding(GO:0002039)
0.2 3.0 GO:0070034 telomerase RNA binding(GO:0070034)
0.2 9.0 GO:0001786 phosphatidylserine binding(GO:0001786)
0.2 4.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.2 5.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.2 6.2 GO:0005109 frizzled binding(GO:0005109)
0.2 0.6 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.2 4.6 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.2 2.9 GO:0031491 nucleosome binding(GO:0031491)
0.2 2.5 GO:0042288 MHC class I protein binding(GO:0042288)
0.2 0.8 GO:0061665 SUMO ligase activity(GO:0061665)
0.2 0.6 GO:0051525 NFAT protein binding(GO:0051525)
0.2 3.4 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.2 0.7 GO:0050632 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
0.2 4.2 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.2 1.1 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.2 0.5 GO:0019002 GMP binding(GO:0019002)
0.2 1.1 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.2 0.9 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.2 28.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 4.8 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.2 1.7 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.2 5.1 GO:0046332 SMAD binding(GO:0046332)
0.2 28.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.2 1.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 1.0 GO:1990446 snRNP binding(GO:0070990) U1 snRNP binding(GO:1990446)
0.1 2.3 GO:0051400 BH domain binding(GO:0051400)
0.1 1.4 GO:0004697 protein kinase C activity(GO:0004697)
0.1 4.7 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.1 29.0 GO:0003682 chromatin binding(GO:0003682)
0.1 3.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 7.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 2.0 GO:0003951 NAD+ kinase activity(GO:0003951)
0.1 24.4 GO:0008022 protein C-terminus binding(GO:0008022)
0.1 0.8 GO:0000182 rDNA binding(GO:0000182)
0.1 8.3 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.1 0.4 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 1.4 GO:0004707 MAP kinase activity(GO:0004707)
0.1 0.5 GO:0050897 cobalt ion binding(GO:0050897)
0.1 1.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 1.2 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 0.3 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 4.6 GO:0019894 kinesin binding(GO:0019894)
0.1 2.9 GO:0050699 WW domain binding(GO:0050699)
0.1 2.6 GO:0031072 heat shock protein binding(GO:0031072)
0.1 1.6 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 5.3 GO:0019905 syntaxin binding(GO:0019905)
0.1 4.5 GO:0005178 integrin binding(GO:0005178)
0.1 0.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 1.6 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 1.3 GO:0008373 sialyltransferase activity(GO:0008373)
0.1 8.9 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1 1.2 GO:0017091 AU-rich element binding(GO:0017091)
0.1 15.6 GO:0046982 protein heterodimerization activity(GO:0046982)
0.1 0.7 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 0.7 GO:0019843 rRNA binding(GO:0019843)
0.1 0.7 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 0.6 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 1.3 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0 0.3 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.3 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.0 0.2 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 1.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.6 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.3 GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.0 0.8 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.9 GO:0000049 tRNA binding(GO:0000049)
0.0 0.9 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.4 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 57.2 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
3.4 187.7 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
3.4 156.4 PID_ATR_PATHWAY ATR signaling pathway
2.5 7.4 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
2.4 202.8 PID_E2F_PATHWAY E2F transcription factor network
2.2 99.3 PID_AURORA_B_PATHWAY Aurora B signaling
1.9 46.6 PID_FOXM1_PATHWAY FOXM1 transcription factor network
1.8 12.6 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
1.5 17.9 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
1.4 41.7 PID_FANCONI_PATHWAY Fanconi anemia pathway
1.4 27.5 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
1.3 6.7 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
1.2 40.4 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
1.1 30.8 ST_GA12_PATHWAY G alpha 12 Pathway
1.0 30.0 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.9 8.5 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.8 8.2 PID_BARD1_PATHWAY BARD1 signaling events
0.8 27.1 PID_RAS_PATHWAY Regulation of Ras family activation
0.7 39.8 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.7 15.0 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.7 6.4 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.7 27.6 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.7 39.3 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.7 30.3 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.7 55.1 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.7 27.8 PID_FGF_PATHWAY FGF signaling pathway
0.7 63.6 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.6 18.0 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.6 31.6 PID_CMYB_PATHWAY C-MYB transcription factor network
0.6 6.4 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.5 10.4 PID_ATM_PATHWAY ATM pathway
0.5 8.0 PID_ERBB4_PATHWAY ErbB4 signaling events
0.5 19.4 PID_BMP_PATHWAY BMP receptor signaling
0.4 12.3 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.4 5.7 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.4 7.0 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.4 15.9 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.4 7.3 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.4 16.6 PID_PLK1_PATHWAY PLK1 signaling events
0.4 8.0 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.4 9.5 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.4 5.3 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.4 11.2 PID_FAS_PATHWAY FAS (CD95) signaling pathway
0.3 11.9 PID_RAC1_PATHWAY RAC1 signaling pathway
0.3 10.9 PID_AP1_PATHWAY AP-1 transcription factor network
0.3 2.9 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.3 2.6 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.3 5.5 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.3 6.0 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.3 9.0 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.3 7.5 PID_CDC42_PATHWAY CDC42 signaling events
0.2 4.9 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.2 3.7 PID_TCR_PATHWAY TCR signaling in naïve CD4+ T cells
0.2 27.4 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.2 1.6 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.2 3.3 PID_IL1_PATHWAY IL1-mediated signaling events
0.2 22.5 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.2 1.7 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.2 5.7 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 17.8 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.1 4.8 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.1 1.8 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 4.6 PID_MTOR_4PATHWAY mTOR signaling pathway
0.1 1.5 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.1 0.7 PID_INTEGRIN1_PATHWAY Beta1 integrin cell surface interactions
0.1 1.1 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.1 0.9 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.4 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 0.3 PID_CXCR4_PATHWAY CXCR4-mediated signaling events
0.0 0.6 PID_ALK1_PATHWAY ALK1 signaling events
0.0 0.2 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
8.0 128.1 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
6.5 6.5 REACTOME_SCFSKP2_MEDIATED_DEGRADATION_OF_P27_P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
5.6 101.1 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
5.6 72.7 REACTOME_PROCESSIVE_SYNTHESIS_ON_THE_LAGGING_STRAND Genes involved in Processive synthesis on the lagging strand
5.0 20.1 REACTOME_DNA_STRAND_ELONGATION Genes involved in DNA strand elongation
4.8 43.6 REACTOME_ACYL_CHAIN_REMODELLING_OF_PS Genes involved in Acyl chain remodelling of PS
4.6 78.9 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
3.8 86.3 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
3.6 81.8 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
3.4 188.9 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
3.1 28.0 REACTOME_SIGNALING_BY_FGFR3_MUTANTS Genes involved in Signaling by FGFR3 mutants
3.0 143.0 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
3.0 14.8 REACTOME_ACTIVATED_POINT_MUTANTS_OF_FGFR2 Genes involved in Activated point mutants of FGFR2
2.8 19.8 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
2.8 19.6 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
2.8 5.5 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
2.4 19.1 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
1.9 24.4 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
1.8 25.6 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
1.7 20.6 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
1.6 33.5 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
1.5 17.9 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
1.4 17.3 REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Activation of the pre-replicative complex
1.4 11.2 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
1.3 22.1 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
1.3 31.1 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
1.2 8.3 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
1.0 3.0 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
1.0 13.7 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
1.0 7.8 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.9 13.2 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.9 18.8 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.9 14.4 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.8 13.4 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.8 19.1 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.7 26.9 REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.7 7.0 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.7 7.0 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.7 5.6 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.7 18.2 REACTOME_KINESINS Genes involved in Kinesins
0.7 7.4 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.6 46.1 REACTOME_MITOTIC_G2_G2_M_PHASES Genes involved in Mitotic G2-G2/M phases
0.6 52.6 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.6 34.1 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.6 18.1 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.5 14.9 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.5 13.3 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.5 8.9 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.5 11.1 REACTOME_REGULATORY_RNA_PATHWAYS Genes involved in Regulatory RNA pathways
0.5 32.6 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.5 4.3 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.5 6.1 REACTOME_REGULATION_OF_APOPTOSIS Genes involved in Regulation of Apoptosis
0.5 11.7 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.4 33.9 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.4 17.6 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.4 5.2 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.4 3.0 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.4 7.5 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.4 9.8 REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.4 6.3 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.4 14.3 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.4 9.6 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.4 9.0 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.4 2.2 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.3 13.1 REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE Genes involved in GPVI-mediated activation cascade
0.3 8.9 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.3 7.6 REACTOME_AMYLOIDS Genes involved in Amyloids
0.3 3.9 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.3 36.6 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.3 2.5 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.3 4.0 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.3 18.4 REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION Genes involved in Antigen processing-Cross presentation
0.3 2.8 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.3 4.3 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 8.9 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.2 20.0 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.2 0.5 REACTOME_ABORTIVE_ELONGATION_OF_HIV1_TRANSCRIPT_IN_THE_ABSENCE_OF_TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.2 8.0 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.2 15.5 REACTOME_APOPTOTIC_EXECUTION_PHASE Genes involved in Apoptotic execution phase
0.2 11.9 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.2 1.5 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.2 4.4 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 8.8 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.2 1.7 REACTOME_RNA_POL_I_TRANSCRIPTION_INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.2 3.8 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.2 2.2 REACTOME_GENERIC_TRANSCRIPTION_PATHWAY Genes involved in Generic Transcription Pathway
0.2 12.0 REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.2 11.4 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.2 2.9 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS Genes involved in CREB phosphorylation through the activation of Ras
0.2 5.7 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.1 2.2 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.1 2.7 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.1 1.4 REACTOME_G_ALPHA1213_SIGNALLING_EVENTS Genes involved in G alpha (12/13) signalling events
0.1 3.5 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 3.0 REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE Genes involved in Late Phase of HIV Life Cycle
0.1 1.1 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 2.3 REACTOME_SIGNALLING_TO_ERKS Genes involved in Signalling to ERKs
0.1 2.2 REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1 1.1 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 1.9 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 1.2 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 2.4 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 1.8 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 0.8 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 2.2 REACTOME_SIGNALING_BY_PDGF Genes involved in Signaling by PDGF
0.1 2.2 REACTOME_TRANSPORT_OF_GLUCOSE_AND_OTHER_SUGARS_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS Genes involved in Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
0.1 1.2 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 0.7 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1 3.8 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.3 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 9.7 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.6 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 1.9 REACTOME_TRANSLATION Genes involved in Translation
0.0 0.8 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.2 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.3 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.2 REACTOME_P75NTR_RECRUITS_SIGNALLING_COMPLEXES Genes involved in p75NTR recruits signalling complexes