Motif ID: Pou4f1_Pou6f1
Z-value: 0.738


Transcription factors associated with Pou4f1_Pou6f1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Pou4f1 | ENSMUSG00000048349.8 | Pou4f1 |
Pou6f1 | ENSMUSG00000009739.10 | Pou6f1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Pou6f1 | mm10_v2_chr15_-_100599983_100600039 | 0.64 | 5.8e-06 | Click! |
Pou4f1 | mm10_v2_chr14_-_104467984_104468041 | -0.27 | 9.0e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.0 | 4.0 | GO:0086046 | membrane depolarization during SA node cell action potential(GO:0086046) |
0.8 | 3.1 | GO:1902724 | positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728) |
0.6 | 2.2 | GO:0009414 | response to water deprivation(GO:0009414) |
0.5 | 1.0 | GO:0014877 | response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
0.4 | 1.3 | GO:0042939 | glutathione transport(GO:0034635) tripeptide transport(GO:0042939) |
0.4 | 2.1 | GO:0002457 | T cell antigen processing and presentation(GO:0002457) |
0.4 | 2.4 | GO:0098707 | ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707) |
0.4 | 1.1 | GO:1904959 | regulation of iron ion transport(GO:0034756) regulation of iron ion transmembrane transport(GO:0034759) elastin biosynthetic process(GO:0051542) copper ion export(GO:0060003) regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959) |
0.4 | 1.1 | GO:0007621 | negative regulation of female receptivity(GO:0007621) |
0.4 | 1.8 | GO:0021856 | cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375) |
0.3 | 2.4 | GO:1903690 | negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
0.3 | 2.7 | GO:0090074 | negative regulation of protein homodimerization activity(GO:0090074) |
0.3 | 1.9 | GO:2000483 | negative regulation of interleukin-8 secretion(GO:2000483) |
0.3 | 1.0 | GO:2000564 | antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187) |
0.3 | 1.2 | GO:0010808 | positive regulation of synaptic vesicle priming(GO:0010808) |
0.3 | 0.6 | GO:1904395 | positive regulation of postsynaptic membrane organization(GO:1901628) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) |
0.3 | 1.9 | GO:0035093 | spermatogenesis, exchange of chromosomal proteins(GO:0035093) |
0.3 | 1.4 | GO:1902774 | late endosome to lysosome transport(GO:1902774) |
0.3 | 4.9 | GO:1901629 | AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688) regulation of presynaptic membrane organization(GO:1901629) |
0.2 | 1.0 | GO:0007256 | activation of JNKK activity(GO:0007256) |
0.2 | 0.7 | GO:0042097 | interleukin-4 biosynthetic process(GO:0042097) regulation of interleukin-4 biosynthetic process(GO:0045402) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007) |
0.2 | 3.0 | GO:1901898 | negative regulation of relaxation of cardiac muscle(GO:1901898) |
0.2 | 1.6 | GO:0071699 | olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699) |
0.2 | 0.4 | GO:2000111 | positive regulation of macrophage apoptotic process(GO:2000111) |
0.2 | 1.0 | GO:1903361 | protein localization to basolateral plasma membrane(GO:1903361) |
0.2 | 1.1 | GO:0035356 | cellular triglyceride homeostasis(GO:0035356) |
0.2 | 2.5 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
0.2 | 1.1 | GO:0070779 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
0.1 | 1.0 | GO:0035754 | B cell chemotaxis(GO:0035754) |
0.1 | 4.0 | GO:0007097 | nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023) |
0.1 | 0.7 | GO:0090310 | negative regulation of methylation-dependent chromatin silencing(GO:0090310) |
0.1 | 0.5 | GO:0036482 | neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384) |
0.1 | 1.4 | GO:0042118 | endothelial cell activation(GO:0042118) |
0.1 | 0.7 | GO:0003406 | retinal pigment epithelium development(GO:0003406) |
0.1 | 0.9 | GO:0071420 | cellular response to histamine(GO:0071420) |
0.1 | 0.5 | GO:0048133 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
0.1 | 1.5 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
0.1 | 0.8 | GO:0010807 | regulation of synaptic vesicle priming(GO:0010807) |
0.1 | 2.6 | GO:0035025 | positive regulation of Rho protein signal transduction(GO:0035025) |
0.1 | 0.8 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
0.1 | 2.1 | GO:0002076 | osteoblast development(GO:0002076) |
0.1 | 0.3 | GO:0035106 | operant conditioning(GO:0035106) |
0.1 | 0.9 | GO:0000712 | resolution of meiotic recombination intermediates(GO:0000712) |
0.1 | 1.0 | GO:0034312 | diol biosynthetic process(GO:0034312) |
0.1 | 0.4 | GO:2001181 | positive regulation of interleukin-10 secretion(GO:2001181) |
0.1 | 0.2 | GO:1903244 | positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) regulation of connective tissue replacement(GO:1905203) |
0.1 | 1.5 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
0.1 | 0.7 | GO:1903608 | protein localization to cytoplasmic stress granule(GO:1903608) |
0.1 | 0.4 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
0.1 | 0.2 | GO:1901475 | pyruvate transmembrane transport(GO:1901475) |
0.1 | 1.3 | GO:0045475 | locomotor rhythm(GO:0045475) |
0.1 | 1.0 | GO:0042541 | hemoglobin biosynthetic process(GO:0042541) |
0.1 | 0.2 | GO:0006780 | uroporphyrinogen III biosynthetic process(GO:0006780) |
0.0 | 0.3 | GO:0097105 | presynaptic membrane assembly(GO:0097105) |
0.0 | 0.3 | GO:0072318 | clathrin coat disassembly(GO:0072318) |
0.0 | 0.2 | GO:0035720 | intraciliary anterograde transport(GO:0035720) |
0.0 | 0.3 | GO:0048859 | formation of anatomical boundary(GO:0048859) |
0.0 | 0.3 | GO:0007296 | vitellogenesis(GO:0007296) |
0.0 | 0.2 | GO:0071894 | histone H2B conserved C-terminal lysine ubiquitination(GO:0071894) |
0.0 | 2.1 | GO:0086010 | membrane depolarization during action potential(GO:0086010) |
0.0 | 0.1 | GO:0050847 | progesterone receptor signaling pathway(GO:0050847) |
0.0 | 0.3 | GO:1900194 | negative regulation of oocyte maturation(GO:1900194) |
0.0 | 3.0 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
0.0 | 4.1 | GO:0043149 | contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149) |
0.0 | 0.9 | GO:0010758 | regulation of macrophage chemotaxis(GO:0010758) |
0.0 | 0.3 | GO:0035095 | behavioral response to nicotine(GO:0035095) |
0.0 | 0.3 | GO:0046548 | retinal rod cell development(GO:0046548) |
0.0 | 0.4 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
0.0 | 0.1 | GO:1900110 | negative regulation of histone H3-K9 dimethylation(GO:1900110) |
0.0 | 0.8 | GO:0009395 | phospholipid catabolic process(GO:0009395) |
0.0 | 1.0 | GO:0015914 | phospholipid transport(GO:0015914) |
0.0 | 1.2 | GO:0010765 | positive regulation of sodium ion transport(GO:0010765) |
0.0 | 0.7 | GO:0061014 | positive regulation of mRNA catabolic process(GO:0061014) |
0.0 | 0.5 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
0.0 | 0.3 | GO:0001553 | luteinization(GO:0001553) |
0.0 | 1.0 | GO:0045773 | positive regulation of axon extension(GO:0045773) |
0.0 | 0.9 | GO:0051220 | cytoplasmic sequestering of protein(GO:0051220) |
0.0 | 1.5 | GO:0060976 | coronary vasculature development(GO:0060976) |
0.0 | 0.1 | GO:0036337 | Fas signaling pathway(GO:0036337) |
0.0 | 0.2 | GO:0042136 | neurotransmitter biosynthetic process(GO:0042136) |
0.0 | 0.3 | GO:0032402 | melanosome transport(GO:0032402) |
0.0 | 0.6 | GO:0043550 | regulation of lipid kinase activity(GO:0043550) |
0.0 | 0.5 | GO:0046677 | response to antibiotic(GO:0046677) |
0.0 | 0.1 | GO:0045835 | negative regulation of meiotic nuclear division(GO:0045835) |
0.0 | 0.2 | GO:2000251 | positive regulation of actin cytoskeleton reorganization(GO:2000251) |
0.0 | 0.2 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
0.0 | 0.6 | GO:0032410 | negative regulation of transporter activity(GO:0032410) |
0.0 | 0.2 | GO:0016486 | peptide hormone processing(GO:0016486) |
0.0 | 0.9 | GO:0009062 | fatty acid catabolic process(GO:0009062) |
0.0 | 0.1 | GO:0006953 | acute-phase response(GO:0006953) |
0.0 | 0.1 | GO:0021942 | radial glia guided migration of Purkinje cell(GO:0021942) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 2.4 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
0.4 | 4.0 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
0.3 | 2.4 | GO:0097433 | dense body(GO:0097433) |
0.3 | 0.8 | GO:0005899 | insulin receptor complex(GO:0005899) |
0.2 | 1.2 | GO:0098831 | presynaptic active zone cytoplasmic component(GO:0098831) |
0.2 | 1.4 | GO:0033263 | CORVET complex(GO:0033263) |
0.2 | 0.8 | GO:0070044 | synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044) |
0.1 | 1.0 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
0.1 | 2.1 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
0.1 | 4.9 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
0.1 | 0.5 | GO:0001533 | cornified envelope(GO:0001533) |
0.1 | 3.0 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
0.1 | 0.6 | GO:0035032 | phosphatidylinositol 3-kinase complex, class III(GO:0035032) |
0.1 | 1.0 | GO:0042612 | MHC class I protein complex(GO:0042612) |
0.1 | 1.9 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
0.1 | 0.7 | GO:0097165 | nuclear stress granule(GO:0097165) |
0.1 | 0.9 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
0.1 | 0.5 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
0.1 | 0.9 | GO:0097539 | ciliary transition fiber(GO:0097539) |
0.1 | 0.7 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
0.1 | 1.5 | GO:0034707 | chloride channel complex(GO:0034707) |
0.1 | 0.2 | GO:0071439 | clathrin complex(GO:0071439) |
0.0 | 1.3 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
0.0 | 0.2 | GO:0005955 | calcineurin complex(GO:0005955) |
0.0 | 1.1 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
0.0 | 5.4 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
0.0 | 0.5 | GO:0036038 | MKS complex(GO:0036038) |
0.0 | 0.9 | GO:0031672 | A band(GO:0031672) |
0.0 | 1.1 | GO:0030673 | axolemma(GO:0030673) |
0.0 | 3.4 | GO:0042641 | actomyosin(GO:0042641) |
0.0 | 2.1 | GO:0000118 | histone deacetylase complex(GO:0000118) |
0.0 | 0.1 | GO:0000235 | astral microtubule(GO:0000235) |
0.0 | 0.3 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
0.0 | 0.1 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
0.0 | 0.3 | GO:0005869 | dynactin complex(GO:0005869) |
0.0 | 0.3 | GO:0030008 | TRAPP complex(GO:0030008) |
0.0 | 2.6 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
0.0 | 0.2 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
0.0 | 0.2 | GO:0097542 | ciliary tip(GO:0097542) |
0.0 | 0.2 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
0.0 | 1.5 | GO:0030017 | sarcomere(GO:0030017) |
0.0 | 0.8 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
0.0 | 1.5 | GO:0005814 | centriole(GO:0005814) |
0.0 | 1.1 | GO:0005811 | lipid particle(GO:0005811) |
0.0 | 6.2 | GO:0015629 | actin cytoskeleton(GO:0015629) |
0.0 | 0.5 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
0.0 | 0.1 | GO:0031315 | extrinsic component of mitochondrial outer membrane(GO:0031315) |
0.0 | 1.8 | GO:0055037 | recycling endosome(GO:0055037) |
0.0 | 1.0 | GO:0001669 | acrosomal vesicle(GO:0001669) |
0.0 | 0.1 | GO:0097255 | R2TP complex(GO:0097255) |
0.0 | 1.9 | GO:0001650 | fibrillar center(GO:0001650) |
0.0 | 0.6 | GO:0031594 | neuromuscular junction(GO:0031594) |
0.0 | 0.2 | GO:0000346 | transcription export complex(GO:0000346) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 4.0 | GO:0086007 | voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007) |
0.5 | 1.9 | GO:0061628 | H3K27me3 modified histone binding(GO:0061628) |
0.4 | 1.6 | GO:0047275 | glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275) |
0.4 | 1.1 | GO:0004658 | propionyl-CoA carboxylase activity(GO:0004658) |
0.4 | 1.1 | GO:0043682 | copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682) |
0.4 | 1.1 | GO:0003846 | 2-acylglycerol O-acyltransferase activity(GO:0003846) |
0.4 | 1.1 | GO:0031752 | D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752) |
0.4 | 1.4 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
0.3 | 3.1 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
0.3 | 2.4 | GO:0015091 | ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510) |
0.3 | 1.0 | GO:0016748 | succinyltransferase activity(GO:0016748) |
0.3 | 0.9 | GO:0016160 | alpha-amylase activity(GO:0004556) amylase activity(GO:0016160) |
0.3 | 1.5 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
0.3 | 0.6 | GO:0035373 | chondroitin sulfate proteoglycan binding(GO:0035373) |
0.3 | 1.3 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
0.2 | 1.0 | GO:0004301 | epoxide hydrolase activity(GO:0004301) |
0.2 | 1.2 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
0.2 | 4.9 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
0.2 | 0.8 | GO:0005483 | soluble NSF attachment protein activity(GO:0005483) |
0.2 | 1.3 | GO:0015651 | quaternary ammonium group transmembrane transporter activity(GO:0015651) |
0.2 | 2.4 | GO:0002162 | dystroglycan binding(GO:0002162) |
0.2 | 1.1 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
0.2 | 2.7 | GO:0048273 | mitogen-activated protein kinase p38 binding(GO:0048273) |
0.2 | 1.0 | GO:0097016 | L27 domain binding(GO:0097016) |
0.2 | 0.9 | GO:1904315 | GABA-gated chloride ion channel activity(GO:0022851) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315) |
0.2 | 2.6 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
0.1 | 1.8 | GO:0038191 | neuropilin binding(GO:0038191) |
0.1 | 3.6 | GO:0000983 | transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983) |
0.1 | 0.9 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
0.1 | 0.5 | GO:0004859 | phospholipase inhibitor activity(GO:0004859) phospholipase A2 inhibitor activity(GO:0019834) |
0.1 | 1.7 | GO:0030881 | beta-2-microglobulin binding(GO:0030881) |
0.1 | 0.6 | GO:0004954 | icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955) |
0.1 | 1.0 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
0.1 | 0.8 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
0.1 | 1.5 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
0.1 | 0.1 | GO:0001851 | complement component C3b binding(GO:0001851) |
0.1 | 3.3 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
0.1 | 0.3 | GO:0046964 | 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964) |
0.1 | 2.1 | GO:0031402 | sodium ion binding(GO:0031402) |
0.1 | 3.2 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
0.1 | 0.6 | GO:0070579 | methylcytosine dioxygenase activity(GO:0070579) |
0.1 | 0.4 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
0.1 | 0.2 | GO:0000099 | sulfur amino acid transmembrane transporter activity(GO:0000099) L-asparagine transmembrane transporter activity(GO:0015182) |
0.1 | 1.0 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
0.1 | 0.5 | GO:0055131 | C3HC4-type RING finger domain binding(GO:0055131) |
0.1 | 0.2 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
0.1 | 0.2 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
0.1 | 0.3 | GO:0003831 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831) |
0.1 | 0.3 | GO:0001032 | RNA polymerase III type 3 promoter DNA binding(GO:0001032) |
0.0 | 0.4 | GO:0015165 | pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165) |
0.0 | 0.8 | GO:0004623 | phospholipase A2 activity(GO:0004623) |
0.0 | 1.0 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
0.0 | 1.4 | GO:0051059 | NF-kappaB binding(GO:0051059) |
0.0 | 0.2 | GO:0033192 | calmodulin-dependent protein phosphatase activity(GO:0033192) |
0.0 | 0.2 | GO:0004852 | uroporphyrinogen-III synthase activity(GO:0004852) |
0.0 | 1.2 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
0.0 | 0.2 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
0.0 | 0.2 | GO:0051429 | corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
0.0 | 2.1 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
0.0 | 0.5 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
0.0 | 0.3 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
0.0 | 2.1 | GO:0002039 | p53 binding(GO:0002039) |
0.0 | 0.4 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
0.0 | 5.7 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
0.0 | 0.5 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
0.0 | 0.6 | GO:0051721 | protein phosphatase 2A binding(GO:0051721) |
0.0 | 2.1 | GO:0051219 | phosphoprotein binding(GO:0051219) |
0.0 | 0.1 | GO:0050347 | trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347) |
0.0 | 0.1 | GO:0032184 | SUMO polymer binding(GO:0032184) |
0.0 | 2.2 | GO:0017124 | SH3 domain binding(GO:0017124) |
0.0 | 2.8 | GO:0000287 | magnesium ion binding(GO:0000287) |
0.0 | 0.0 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
0.0 | 0.9 | GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) |
0.0 | 0.4 | GO:0017091 | AU-rich element binding(GO:0017091) |
0.0 | 0.7 | GO:0004004 | RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) |
0.0 | 0.5 | GO:0043621 | protein self-association(GO:0043621) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 3.1 | ST_STAT3_PATHWAY | STAT3 Pathway |
0.1 | 3.4 | PID_TCR_CALCIUM_PATHWAY | Calcium signaling in the CD4+ TCR pathway |
0.1 | 2.6 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
0.0 | 3.8 | PID_CDC42_PATHWAY | CDC42 signaling events |
0.0 | 2.7 | PID_ARF6_TRAFFICKING_PATHWAY | Arf6 trafficking events |
0.0 | 0.6 | PID_SYNDECAN_3_PATHWAY | Syndecan-3-mediated signaling events |
0.0 | 0.5 | PID_IL12_STAT4_PATHWAY | IL12 signaling mediated by STAT4 |
0.0 | 3.7 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.0 | 0.8 | PID_INSULIN_PATHWAY | Insulin Pathway |
0.0 | 1.0 | PID_FOXO_PATHWAY | FoxO family signaling |
0.0 | 0.3 | PID_PDGFRA_PATHWAY | PDGFR-alpha signaling pathway |
0.0 | 0.2 | PID_S1P_S1P4_PATHWAY | S1P4 pathway |
0.0 | 1.7 | PID_AR_PATHWAY | Coregulation of Androgen receptor activity |
0.0 | 1.0 | PID_TNF_PATHWAY | TNF receptor signaling pathway |
0.0 | 0.4 | PID_MAPK_TRK_PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 3.1 | REACTOME_IL_6_SIGNALING | Genes involved in Interleukin-6 signaling |
0.2 | 1.3 | REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
0.2 | 0.6 | REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS | Genes involved in Eicosanoid ligand-binding receptors |
0.1 | 1.0 | REACTOME_ENDOGENOUS_STEROLS | Genes involved in Endogenous sterols |
0.1 | 1.2 | REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
0.1 | 1.8 | REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
0.1 | 3.5 | REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |
0.1 | 1.5 | REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
0.1 | 4.3 | REACTOME_DARPP_32_EVENTS | Genes involved in DARPP-32 events |
0.1 | 3.0 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
0.1 | 1.1 | REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
0.1 | 0.9 | REACTOME_GABA_A_RECEPTOR_ACTIVATION | Genes involved in GABA A receptor activation |
0.1 | 2.1 | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
0.1 | 1.9 | REACTOME_MYOGENESIS | Genes involved in Myogenesis |
0.1 | 1.2 | REACTOME_METABOLISM_OF_PORPHYRINS | Genes involved in Metabolism of porphyrins |
0.0 | 0.4 | REACTOME_PD1_SIGNALING | Genes involved in PD-1 signaling |
0.0 | 1.8 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | Genes involved in Ion transport by P-type ATPases |
0.0 | 0.2 | REACTOME_PEPTIDE_HORMONE_BIOSYNTHESIS | Genes involved in Peptide hormone biosynthesis |
0.0 | 0.6 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
0.0 | 1.3 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
0.0 | 1.2 | REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
0.0 | 1.2 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
0.0 | 0.2 | REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
0.0 | 1.5 | REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |
0.0 | 0.6 | REACTOME_SMOOTH_MUSCLE_CONTRACTION | Genes involved in Smooth Muscle Contraction |
0.0 | 1.1 | REACTOME_TRIGLYCERIDE_BIOSYNTHESIS | Genes involved in Triglyceride Biosynthesis |
0.0 | 0.3 | REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
0.0 | 0.9 | REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
0.0 | 0.2 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |