Motif ID: Gfi1_Gfi1b

Z-value: 1.321

Transcription factors associated with Gfi1_Gfi1b:

Gene SymbolEntrez IDGene Name
Gfi1 ENSMUSG00000029275.11 Gfi1
Gfi1b ENSMUSG00000026815.8 Gfi1b






Network of associatons between targets according to the STRING database.



First level regulatory network of Gfi1_Gfi1b

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_23248264 22.089 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr16_-_26989974 13.699 ENSMUST00000089832.4
Gmnc
geminin coiled-coil domain containing
chr7_+_62376979 10.351 ENSMUST00000080403.5
Magel2
melanoma antigen, family L, 2
chr7_-_17062384 6.605 ENSMUST00000153833.1
ENSMUST00000108492.2
Hif3a

hypoxia inducible factor 3, alpha subunit

chr10_+_13090788 6.466 ENSMUST00000121646.1
ENSMUST00000121325.1
ENSMUST00000121766.1
Plagl1


pleiomorphic adenoma gene-like 1


chr13_+_35659856 6.343 ENSMUST00000075220.6
Cdyl
chromodomain protein, Y chromosome-like
chr9_+_3027439 6.209 ENSMUST00000177875.1
ENSMUST00000179982.1
Gm10717

predicted gene 10717

chr7_-_62464505 6.187 ENSMUST00000094339.2
Peg12
paternally expressed 12
chr9_+_3005125 5.911 ENSMUST00000179881.1
Gm11168
predicted gene 11168
chr9_+_3000922 5.827 ENSMUST00000151376.2
Gm10722
predicted gene 10722
chr9_-_70421533 5.711 ENSMUST00000034742.6
Ccnb2
cyclin B2
chr9_+_3034599 5.413 ENSMUST00000178641.1
Gm17535
predicted gene, 17535
chr9_+_3013140 5.370 ENSMUST00000143083.2
Gm10721
predicted gene 10721
chr18_+_50030977 5.351 ENSMUST00000145726.1
ENSMUST00000128377.1
Tnfaip8

tumor necrosis factor, alpha-induced protein 8

chr11_+_112782182 4.980 ENSMUST00000000579.2
Sox9
SRY-box containing gene 9
chr17_-_70849644 4.882 ENSMUST00000134654.1
ENSMUST00000172229.1
ENSMUST00000127719.1
Tgif1


TGFB-induced factor homeobox 1


chr9_+_3023547 4.864 ENSMUST00000099046.3
Gm10718
predicted gene 10718
chr8_-_61591130 4.777 ENSMUST00000135439.1
ENSMUST00000121200.1
Palld

palladin, cytoskeletal associated protein

chr9_+_3017408 4.723 ENSMUST00000099049.3
Gm10719
predicted gene 10719
chr5_+_75075464 4.687 ENSMUST00000160104.1
ENSMUST00000040477.3
Gsx2

GS homeobox 2

chr9_+_3025417 4.679 ENSMUST00000075573.6
Gm10717
predicted gene 10717
chr9_+_3015654 4.596 ENSMUST00000099050.3
Gm10720
predicted gene 10720
chr13_+_104229366 4.581 ENSMUST00000022227.6
Cenpk
centromere protein K
chr7_-_135716374 4.471 ENSMUST00000033310.7
Mki67
antigen identified by monoclonal antibody Ki 67
chr11_-_84525514 4.272 ENSMUST00000018842.7
Lhx1
LIM homeobox protein 1
chr9_+_3037111 4.253 ENSMUST00000177969.1
Gm10715
predicted gene 10715
chr9_+_3036877 4.138 ENSMUST00000155807.2
Gm10715
predicted gene 10715
chr8_-_84822823 3.970 ENSMUST00000065539.4
Dand5
DAN domain family, member 5
chr12_+_109544498 3.845 ENSMUST00000126289.1
Meg3
maternally expressed 3
chr14_-_103844173 3.757 ENSMUST00000022718.3
Ednrb
endothelin receptor type B
chr1_+_169969409 3.703 ENSMUST00000180638.1
3110045C21Rik
RIKEN cDNA 3110045C21 gene
chr14_-_47411666 3.606 ENSMUST00000111778.3
Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr9_+_3004457 3.559 ENSMUST00000178348.1
Gm11168
predicted gene 11168
chr11_+_84525647 3.554 ENSMUST00000134800.1
1500016L03Rik
RIKEN cDNA 1500016L03 gene
chr9_-_79977782 3.469 ENSMUST00000093811.4
Filip1
filamin A interacting protein 1
chr8_+_83955507 3.403 ENSMUST00000005607.8
Asf1b
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr6_+_6863269 3.329 ENSMUST00000160937.2
ENSMUST00000171311.1
Dlx6

distal-less homeobox 6

chr19_+_6084983 3.324 ENSMUST00000025704.2
Cdca5
cell division cycle associated 5
chr2_-_71546745 3.298 ENSMUST00000024159.6
Dlx2
distal-less homeobox 2
chr7_-_99353104 3.288 ENSMUST00000169437.1
ENSMUST00000094154.4
Serpinh1

serine (or cysteine) peptidase inhibitor, clade H, member 1

chr8_+_106935720 3.243 ENSMUST00000047425.3
Sntb2
syntrophin, basic 2
chr9_+_3018753 3.213 ENSMUST00000179272.1
Gm10719
predicted gene 10719
chr11_+_44617310 3.191 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
Ebf1


early B cell factor 1


chr7_+_90426312 3.130 ENSMUST00000061391.7
Ccdc89
coiled-coil domain containing 89
chr11_+_84525669 3.099 ENSMUST00000126072.1
ENSMUST00000128121.1
1500016L03Rik

RIKEN cDNA 1500016L03 gene

chr15_+_79030874 3.086 ENSMUST00000171999.1
ENSMUST00000006544.7
Gcat

glycine C-acetyltransferase (2-amino-3-ketobutyrate-coenzyme A ligase)

chr5_+_33658123 3.065 ENSMUST00000074849.6
ENSMUST00000079534.4
Tacc3

transforming, acidic coiled-coil containing protein 3

chr2_+_25372315 3.055 ENSMUST00000028329.6
ENSMUST00000114293.2
ENSMUST00000100323.2
Sapcd2


suppressor APC domain containing 2


chr7_-_144939823 2.976 ENSMUST00000093962.4
Ccnd1
cyclin D1
chr2_-_58052832 2.975 ENSMUST00000090940.5
Ermn
ermin, ERM-like protein
chr12_+_113156403 2.919 ENSMUST00000049271.8
4930427A07Rik
RIKEN cDNA 4930427A07 gene
chr3_-_25212720 2.890 ENSMUST00000091289.3
Gm10259
predicted pseudogene 10259
chr11_-_78550777 2.729 ENSMUST00000103242.4
Tmem97
transmembrane protein 97
chr4_+_105157339 2.678 ENSMUST00000064139.7
Ppap2b
phosphatidic acid phosphatase type 2B
chr3_-_154330543 2.677 ENSMUST00000184966.1
ENSMUST00000177846.2
Lhx8

LIM homeobox protein 8

chr19_+_41911851 2.666 ENSMUST00000011896.6
Pgam1
phosphoglycerate mutase 1
chr6_+_4755327 2.663 ENSMUST00000176551.1
Peg10
paternally expressed 10
chr5_-_88676135 2.612 ENSMUST00000078945.5
Grsf1
G-rich RNA sequence binding factor 1
chr19_-_34877880 2.560 ENSMUST00000112460.1
Pank1
pantothenate kinase 1
chrX_-_133688978 2.545 ENSMUST00000149154.1
ENSMUST00000167944.1
Pcdh19

protocadherin 19

chr2_-_104742802 2.490 ENSMUST00000028595.7
Depdc7
DEP domain containing 7
chr4_+_136143497 2.479 ENSMUST00000008016.2
Id3
inhibitor of DNA binding 3
chr7_-_38107490 2.349 ENSMUST00000108023.3
Ccne1
cyclin E1
chr4_+_89137122 2.313 ENSMUST00000058030.7
Mtap
methylthioadenosine phosphorylase
chr17_-_31277327 2.300 ENSMUST00000024832.7
Rsph1
radial spoke head 1 homolog (Chlamydomonas)
chr12_+_108334341 2.294 ENSMUST00000021684.4
Cyp46a1
cytochrome P450, family 46, subfamily a, polypeptide 1
chr3_+_102010138 2.199 ENSMUST00000066187.4
Nhlh2
nescient helix loop helix 2
chr3_+_94372794 2.178 ENSMUST00000029795.3
Rorc
RAR-related orphan receptor gamma
chr1_+_146495621 2.167 ENSMUST00000074622.4
Brinp3
bone morphogenetic protein/retinoic acid inducible neural specific 3
chr13_-_23571151 2.121 ENSMUST00000102969.3
Hist1h2ae
histone cluster 1, H2ae
chr14_+_12189943 2.099 ENSMUST00000119888.1
Ptprg
protein tyrosine phosphatase, receptor type, G
chr2_+_13573927 2.008 ENSMUST00000141365.1
ENSMUST00000028062.2
Vim

vimentin

chr18_+_57133065 1.983 ENSMUST00000075770.6
Megf10
multiple EGF-like-domains 10
chr1_-_192092540 1.981 ENSMUST00000085573.6
Traf5
TNF receptor-associated factor 5
chr2_+_20519776 1.947 ENSMUST00000114604.2
ENSMUST00000066509.3
Etl4

enhancer trap locus 4

chr4_-_135573623 1.927 ENSMUST00000105855.1
Grhl3
grainyhead-like 3 (Drosophila)
chr13_-_71963713 1.924 ENSMUST00000077337.8
Irx1
Iroquois related homeobox 1 (Drosophila)
chr18_+_34751803 1.923 ENSMUST00000181453.1
ENSMUST00000181641.1
2010110K18Rik

RIKEN cDNA 2010110K18 gene

chr7_+_24507122 1.912 ENSMUST00000177205.1
Zfp428
zinc finger protein 428
chr13_-_104178399 1.896 ENSMUST00000179891.1
ENSMUST00000022224.9
ENSMUST00000141557.1
ENSMUST00000144060.1
ENSMUST00000091264.1
Trappc13



Trappc13
trafficking protein particle complex 13



trafficking protein particle complex 13
chr1_-_189688074 1.887 ENSMUST00000171929.1
ENSMUST00000165962.1
Cenpf

centromere protein F

chr13_+_15463837 1.884 ENSMUST00000110510.3
Gli3
GLI-Kruppel family member GLI3
chr12_+_109545390 1.861 ENSMUST00000146701.1
Meg3
maternally expressed 3
chr10_+_94036001 1.835 ENSMUST00000020208.4
Fgd6
FYVE, RhoGEF and PH domain containing 6
chr3_-_92083132 1.811 ENSMUST00000058150.6
Lor
loricrin
chr2_-_59882556 1.808 ENSMUST00000128671.1
ENSMUST00000028368.7
ENSMUST00000140475.1
Wdsub1


WD repeat, SAM and U-box domain containing 1


chr1_+_161070767 1.794 ENSMUST00000111618.1
ENSMUST00000111620.3
ENSMUST00000028035.7
Cenpl


centromere protein L


chr5_+_33658567 1.770 ENSMUST00000114426.3
Tacc3
transforming, acidic coiled-coil containing protein 3
chr9_-_44251464 1.717 ENSMUST00000034618.4
Pdzd3
PDZ domain containing 3
chr18_+_50051702 1.697 ENSMUST00000134348.1
ENSMUST00000153873.2
Tnfaip8

tumor necrosis factor, alpha-induced protein 8

chr18_-_74961252 1.697 ENSMUST00000066532.4
Lipg
lipase, endothelial
chr1_+_10993452 1.648 ENSMUST00000027056.5
Prex2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr7_+_24507006 1.642 ENSMUST00000176880.1
Zfp428
zinc finger protein 428
chr15_-_56694525 1.622 ENSMUST00000050544.7
Has2
hyaluronan synthase 2
chr15_+_99074968 1.620 ENSMUST00000039665.6
Troap
trophinin associated protein
chrX_-_72274747 1.616 ENSMUST00000064780.3
Gabre
gamma-aminobutyric acid (GABA) A receptor, subunit epsilon
chr2_-_26092149 1.616 ENSMUST00000114159.2
Nacc2
nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
chr14_-_68124836 1.607 ENSMUST00000111089.1
ENSMUST00000022638.5
Nefm

neurofilament, medium polypeptide

chr8_-_116732991 1.605 ENSMUST00000109102.2
Cdyl2
chromodomain protein, Y chromosome-like 2
chr12_-_17176888 1.595 ENSMUST00000170580.1
Kcnf1
potassium voltage-gated channel, subfamily F, member 1
chr5_+_144545883 1.585 ENSMUST00000071782.6
Nptx2
neuronal pentraxin 2
chr7_-_70360593 1.579 ENSMUST00000032768.7
Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr8_+_12395287 1.541 ENSMUST00000180353.1
Sox1
SRY-box containing gene 1
chr6_+_30568367 1.539 ENSMUST00000049251.5
Cpa4
carboxypeptidase A4
chr5_-_44102032 1.501 ENSMUST00000171543.1
Prom1
prominin 1
chr8_+_68880491 1.453 ENSMUST00000015712.8
Lpl
lipoprotein lipase
chr10_+_102158858 1.434 ENSMUST00000138522.1
ENSMUST00000163753.1
ENSMUST00000138016.1
Mgat4c


mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)


chr5_+_115845229 1.408 ENSMUST00000137952.1
ENSMUST00000148245.1
Cit

citron

chr7_+_24507057 1.378 ENSMUST00000071361.6
Zfp428
zinc finger protein 428
chr4_+_116596672 1.364 ENSMUST00000051869.7
Ccdc17
coiled-coil domain containing 17
chr5_-_44101668 1.363 ENSMUST00000087441.4
ENSMUST00000074113.6
Prom1

prominin 1

chr4_+_41135743 1.361 ENSMUST00000040008.3
Ube2r2
ubiquitin-conjugating enzyme E2R 2
chr14_+_46882854 1.340 ENSMUST00000022386.8
ENSMUST00000100672.3
Samd4

sterile alpha motif domain containing 4

chrX_-_143827391 1.332 ENSMUST00000087316.5
Capn6
calpain 6
chr10_+_94575257 1.331 ENSMUST00000121471.1
Tmcc3
transmembrane and coiled coil domains 3
chr2_-_59882541 1.330 ENSMUST00000102751.2
Wdsub1
WD repeat, SAM and U-box domain containing 1
chr11_+_94328242 1.327 ENSMUST00000021227.5
Ankrd40
ankyrin repeat domain 40
chr13_+_21717626 1.297 ENSMUST00000091754.2
Hist1h3h
histone cluster 1, H3h
chr11_+_117232254 1.294 ENSMUST00000106354.2
Sept9
septin 9
chr11_+_40733936 1.278 ENSMUST00000127382.1
Nudcd2
NudC domain containing 2
chr11_-_40733373 1.276 ENSMUST00000020579.8
Hmmr
hyaluronan mediated motility receptor (RHAMM)
chr2_-_57113053 1.274 ENSMUST00000112627.1
Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr11_+_40733639 1.264 ENSMUST00000020578.4
Nudcd2
NudC domain containing 2
chr13_+_5861489 1.264 ENSMUST00000000080.6
Klf6
Kruppel-like factor 6
chr12_-_111485808 1.255 ENSMUST00000010673.5
Gm266
predicted gene 266
chr18_+_34625009 1.249 ENSMUST00000166044.1
Kif20a
kinesin family member 20A
chr1_-_180330550 1.245 ENSMUST00000050581.3
Gm5069
predicted pseudogene 5069
chr7_+_45215753 1.228 ENSMUST00000033060.6
ENSMUST00000155313.1
ENSMUST00000107801.1
Tead2


TEA domain family member 2


chr7_+_62348277 1.171 ENSMUST00000038775.4
Ndn
necdin
chr11_-_33163072 1.154 ENSMUST00000093201.6
ENSMUST00000101375.4
ENSMUST00000109354.3
ENSMUST00000075641.3
Npm1



nucleophosmin 1



chr3_-_97297778 1.142 ENSMUST00000181368.1
Gm17608
predicted gene, 17608
chr8_-_78821136 1.140 ENSMUST00000130325.1
ENSMUST00000051867.6
Lsm6

LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)

chr5_-_51553896 1.138 ENSMUST00000132734.1
Ppargc1a
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
chr6_-_23132981 1.138 ENSMUST00000031707.7
Aass
aminoadipate-semialdehyde synthase
chr3_+_124321031 1.135 ENSMUST00000058994.4
Tram1l1
translocation associated membrane protein 1-like 1
chrX_+_71962971 1.101 ENSMUST00000048790.6
Prrg3
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr6_+_15185203 1.082 ENSMUST00000154448.1
Foxp2
forkhead box P2
chr17_-_29264115 1.078 ENSMUST00000024802.8
Ppil1
peptidylprolyl isomerase (cyclophilin)-like 1
chr4_-_72852622 1.071 ENSMUST00000179234.1
ENSMUST00000078617.4
Aldoart1

aldolase 1 A, retrogene 1

chr1_+_135232045 1.070 ENSMUST00000110798.3
Gm4204
predicted gene 4204
chr7_+_19489045 1.068 ENSMUST00000011407.7
ENSMUST00000137613.1
Exoc3l2

exocyst complex component 3-like 2

chr10_-_23787195 1.052 ENSMUST00000073926.6
Rps12
ribosomal protein S12
chr11_+_67078293 1.047 ENSMUST00000108689.1
ENSMUST00000165221.1
ENSMUST00000007301.7
Myh3


myosin, heavy polypeptide 3, skeletal muscle, embryonic


chr17_+_43667389 1.041 ENSMUST00000170988.1
Cyp39a1
cytochrome P450, family 39, subfamily a, polypeptide 1
chr16_-_58523349 1.041 ENSMUST00000137035.1
St3gal6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr13_+_93304066 1.040 ENSMUST00000109493.1
Homer1
homer homolog 1 (Drosophila)
chr13_-_74062262 1.039 ENSMUST00000036456.6
Cep72
centrosomal protein 72
chr10_-_62231208 1.027 ENSMUST00000047883.9
Tspan15
tetraspanin 15
chr17_-_85688252 1.025 ENSMUST00000024947.7
ENSMUST00000163568.2
Six2

sine oculis-related homeobox 2

chr7_+_24507099 1.025 ENSMUST00000177228.1
Zfp428
zinc finger protein 428
chr18_+_34624621 1.019 ENSMUST00000167161.1
Kif20a
kinesin family member 20A
chr10_+_25359798 1.017 ENSMUST00000053748.8
Epb4.1l2
erythrocyte protein band 4.1-like 2
chr15_-_55090422 1.004 ENSMUST00000110231.1
ENSMUST00000023059.6
Dscc1

defective in sister chromatid cohesion 1 homolog (S. cerevisiae)

chr14_+_21052574 0.999 ENSMUST00000045376.9
Adk
adenosine kinase
chr2_+_143546144 0.984 ENSMUST00000028905.9
Pcsk2
proprotein convertase subtilisin/kexin type 2
chr5_-_37824580 0.983 ENSMUST00000063116.9
Msx1
msh homeobox 1
chr4_-_99829180 0.976 ENSMUST00000146258.1
Itgb3bp
integrin beta 3 binding protein (beta3-endonexin)
chr16_-_45953565 0.965 ENSMUST00000134802.1
Phldb2
pleckstrin homology-like domain, family B, member 2
chr6_+_40471352 0.965 ENSMUST00000114779.2
ENSMUST00000031971.6
ENSMUST00000121360.1
ENSMUST00000117411.1
ENSMUST00000117830.1
Ssbp1




single-stranded DNA binding protein 1




chr4_-_35845204 0.964 ENSMUST00000164772.1
ENSMUST00000065173.2
Lingo2

leucine rich repeat and Ig domain containing 2

chr4_+_11558914 0.963 ENSMUST00000178703.1
ENSMUST00000095145.5
ENSMUST00000108306.2
ENSMUST00000070755.6
Rad54b



RAD54 homolog B (S. cerevisiae)



chr18_-_25753852 0.962 ENSMUST00000025117.6
ENSMUST00000115816.2
Celf4

CUGBP, Elav-like family member 4

chr9_-_114564315 0.952 ENSMUST00000111816.2
Trim71
tripartite motif-containing 71
chr5_+_123907175 0.943 ENSMUST00000023869.8
Denr
density-regulated protein
chr19_+_55741810 0.942 ENSMUST00000111657.3
ENSMUST00000061496.9
ENSMUST00000041717.7
ENSMUST00000111662.4
Tcf7l2



transcription factor 7 like 2, T cell specific, HMG box



chr2_+_143915273 0.939 ENSMUST00000103172.3
Dstn
destrin
chr14_+_60768120 0.938 ENSMUST00000025940.6
C1qtnf9
C1q and tumor necrosis factor related protein 9
chr13_+_23571382 0.934 ENSMUST00000079251.5
Hist1h2bg
histone cluster 1, H2bg
chr6_+_86365673 0.929 ENSMUST00000071492.7
Fam136a
family with sequence similarity 136, member A
chr2_+_27886416 0.928 ENSMUST00000028280.7
Col5a1
collagen, type V, alpha 1
chrX_-_152016269 0.919 ENSMUST00000026288.4
Ribc1
RIB43A domain with coiled-coils 1
chr12_+_38780817 0.913 ENSMUST00000160856.1
Etv1
ets variant gene 1
chr11_-_31671727 0.913 ENSMUST00000109415.1
Bod1
biorientation of chromosomes in cell division 1
chr12_-_84617326 0.912 ENSMUST00000021666.4
Abcd4
ATP-binding cassette, sub-family D (ALD), member 4
chr7_+_67647405 0.910 ENSMUST00000032774.8
ENSMUST00000107471.1
Ttc23

tetratricopeptide repeat domain 23

chr6_+_82041623 0.905 ENSMUST00000042974.8
Eva1a
eva-1 homolog A (C. elegans)
chr7_+_83755904 0.903 ENSMUST00000051522.8
ENSMUST00000042280.7
Gm7964

predicted gene 7964

chr17_-_12940317 0.899 ENSMUST00000160378.1
ENSMUST00000043923.5
Acat3

acetyl-Coenzyme A acetyltransferase 3

chrX_-_8193387 0.894 ENSMUST00000143223.1
ENSMUST00000033509.8
Ebp

phenylalkylamine Ca2+ antagonist (emopamil) binding protein

chr10_-_5805412 0.892 ENSMUST00000019907.7
Fbxo5
F-box protein 5
chr17_+_64600702 0.888 ENSMUST00000086723.3
Man2a1
mannosidase 2, alpha 1
chr11_-_5878207 0.881 ENSMUST00000102922.3
Pold2
polymerase (DNA directed), delta 2, regulatory subunit
chr3_+_32817520 0.879 ENSMUST00000072312.5
ENSMUST00000108228.1
Usp13

ubiquitin specific peptidase 13 (isopeptidase T-3)

chr1_+_137928100 0.877 ENSMUST00000054333.2
A130050O07Rik
RIKEN cDNA A130050O07 gene
chr8_+_13339656 0.871 ENSMUST00000170909.1
Tfdp1
transcription factor Dp 1
chr1_+_19208914 0.865 ENSMUST00000027059.4
Tfap2b
transcription factor AP-2 beta
chr5_+_90891234 0.864 ENSMUST00000031327.8
Cxcl1
chemokine (C-X-C motif) ligand 1
chrX_-_7188713 0.862 ENSMUST00000004428.7
Clcn5
chloride channel 5
chr11_-_98625661 0.859 ENSMUST00000104933.1
Gm12355
predicted gene 12355
chr11_+_94327984 0.855 ENSMUST00000107818.2
ENSMUST00000051221.6
Ankrd40

ankyrin repeat domain 40

chr17_+_71204647 0.850 ENSMUST00000126681.1
Lpin2
lipin 2
chr2_-_126675538 0.847 ENSMUST00000103227.1
ENSMUST00000110425.2
ENSMUST00000089745.4
Gabpb1


GA repeat binding protein, beta 1


chr10_-_81167896 0.843 ENSMUST00000005064.7
Pias4
protein inhibitor of activated STAT 4
chr13_-_23762378 0.840 ENSMUST00000091701.2
Hist1h3a
histone cluster 1, H3a
chr10_+_73821857 0.834 ENSMUST00000177128.1
ENSMUST00000064562.7
ENSMUST00000129404.2
ENSMUST00000105426.3
ENSMUST00000131321.2
ENSMUST00000126920.2
ENSMUST00000147189.2
ENSMUST00000105424.3
ENSMUST00000092420.6
ENSMUST00000105429.3
ENSMUST00000131724.2
ENSMUST00000152655.2
ENSMUST00000151116.2
ENSMUST00000155701.2
ENSMUST00000152819.2
ENSMUST00000125517.2
ENSMUST00000124046.1
ENSMUST00000149977.2
ENSMUST00000146682.1
ENSMUST00000177107.1
Pcdh15



















protocadherin 15



















chr2_+_35132194 0.831 ENSMUST00000113034.1
ENSMUST00000113037.3
ENSMUST00000113033.2
Cep110


centrosomal protein 110


chr1_-_55088024 0.825 ENSMUST00000027123.8
Hspd1
heat shock protein 1 (chaperonin)
chr2_+_109917639 0.825 ENSMUST00000046548.7
ENSMUST00000111037.2
Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chr10_-_128626464 0.825 ENSMUST00000026420.5
Rps26
ribosomal protein S26
chrX_-_75875101 0.822 ENSMUST00000114059.3
Pls3
plastin 3 (T-isoform)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 22.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
2.2 4.5 GO:1990705 cholangiocyte proliferation(GO:1990705)
1.8 7.1 GO:2000768 positive regulation of epithelial cell differentiation involved in kidney development(GO:2000698) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
1.7 5.0 GO:0035622 intrahepatic bile duct development(GO:0035622) renal vesicle induction(GO:0072034)
1.3 4.0 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
1.3 3.8 GO:0014826 vein smooth muscle contraction(GO:0014826)
1.1 3.3 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
1.1 3.3 GO:0061075 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.9 2.7 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.8 3.3 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.7 10.3 GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.6 1.9 GO:0060364 frontal suture morphogenesis(GO:0060364)
0.6 1.8 GO:0033566 gamma-tubulin complex localization(GO:0033566)
0.5 1.6 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.5 1.0 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.5 1.9 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.5 1.4 GO:1902336 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336)
0.5 3.3 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.4 2.2 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.4 1.7 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.4 0.8 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.4 16.0 GO:0006270 DNA replication initiation(GO:0006270)
0.4 4.1 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.4 1.6 GO:1900623 positive regulation of keratinocyte proliferation(GO:0010838) regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.4 1.6 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.4 1.2 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448) rRNA export from nucleus(GO:0006407)
0.4 1.1 GO:0006553 lysine metabolic process(GO:0006553)
0.4 2.2 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.4 1.8 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.4 0.4 GO:0071335 hair follicle cell proliferation(GO:0071335)
0.4 1.1 GO:0002842 positive regulation of T cell mediated immune response to tumor cell(GO:0002842) protein import into mitochondrial intermembrane space(GO:0045041)
0.3 4.8 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.3 2.7 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.3 3.3 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.3 3.0 GO:0070141 response to UV-A(GO:0070141)
0.3 1.0 GO:0030070 insulin processing(GO:0030070)
0.3 4.9 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.3 1.3 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986) general adaptation syndrome(GO:0051866)
0.3 1.6 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.3 0.9 GO:0035523 protein K29-linked deubiquitination(GO:0035523) protein K6-linked deubiquitination(GO:0044313)
0.3 0.9 GO:0097274 urea homeostasis(GO:0097274)
0.3 0.6 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.3 0.8 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.3 0.8 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.3 2.2 GO:0072615 interleukin-17 secretion(GO:0072615)
0.3 1.8 GO:0031424 keratinization(GO:0031424)
0.3 1.5 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.3 1.0 GO:0097168 condensed mesenchymal cell proliferation(GO:0072137) mesenchymal stem cell proliferation(GO:0097168)
0.3 1.0 GO:0060578 extraocular skeletal muscle development(GO:0002074) subthalamic nucleus development(GO:0021763) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.3 4.8 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.2 1.0 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.2 1.0 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.2 0.5 GO:0046881 positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.2 0.9 GO:0030043 actin filament fragmentation(GO:0030043)
0.2 0.2 GO:1901630 negative regulation of presynaptic membrane organization(GO:1901630)
0.2 0.9 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.2 0.7 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.2 0.9 GO:1900150 neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) regulation of defense response to fungus(GO:1900150)
0.2 1.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.2 1.0 GO:0034421 post-translational protein acetylation(GO:0034421)
0.2 0.4 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.2 6.2 GO:0000578 embryonic axis specification(GO:0000578)
0.2 0.8 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.2 0.6 GO:0042275 error-free postreplication DNA repair(GO:0042275)
0.2 0.6 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.2 5.5 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.2 1.9 GO:0061436 establishment of skin barrier(GO:0061436)
0.2 1.7 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.2 4.1 GO:0030903 notochord development(GO:0030903)
0.2 2.6 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.2 4.6 GO:0008340 determination of adult lifespan(GO:0008340)
0.2 0.5 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.2 0.5 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.2 1.0 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.2 1.9 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.2 2.9 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.2 0.6 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.2 0.2 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.2 1.2 GO:0055064 carbon dioxide transport(GO:0015670) chloride ion homeostasis(GO:0055064)
0.2 0.9 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 0.9 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 0.4 GO:0032240 RNA import into nucleus(GO:0006404) mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.1 1.9 GO:0060013 righting reflex(GO:0060013)
0.1 0.9 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334)
0.1 0.4 GO:0009106 lipoate metabolic process(GO:0009106)
0.1 6.0 GO:0043029 T cell homeostasis(GO:0043029)
0.1 0.7 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.1 0.6 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.1 0.4 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520) positive regulation of reciprocal meiotic recombination(GO:0010845)
0.1 0.4 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.1 0.2 GO:0071873 response to norepinephrine(GO:0071873)
0.1 0.5 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.1 0.3 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.1 1.3 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.1 0.4 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.1 0.6 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.1 0.9 GO:0006013 mannose metabolic process(GO:0006013)
0.1 0.6 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.1 0.9 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.1 0.7 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.7 GO:0060046 regulation of acrosome reaction(GO:0060046)
0.1 0.4 GO:0030576 Cajal body organization(GO:0030576)
0.1 0.9 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.5 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.5 GO:0019731 antimicrobial humoral response(GO:0019730) antibacterial humoral response(GO:0019731)
0.1 1.1 GO:0051601 exocyst localization(GO:0051601)
0.1 0.7 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.1 6.5 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.1 0.2 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.1 0.3 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.1 1.1 GO:0033005 positive regulation of mast cell activation(GO:0033005) positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.1 0.3 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 2.2 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.1 5.2 GO:0050830 defense response to Gram-positive bacterium(GO:0050830)
0.1 0.7 GO:1900016 negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.1 0.4 GO:0061085 regulation of histone H3-K27 methylation(GO:0061085) positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 0.3 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.1 1.7 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 0.9 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.1 0.2 GO:0014738 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.1 0.5 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 0.3 GO:1902340 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.1 0.8 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.3 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.1 0.1 GO:0002572 pro-T cell differentiation(GO:0002572)
0.1 0.2 GO:0042228 interleukin-8 biosynthetic process(GO:0042228) regulation of interleukin-8 biosynthetic process(GO:0045414)
0.1 0.6 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.3 GO:0032053 ciliary basal body organization(GO:0032053)
0.1 0.9 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.1 0.5 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.4 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 0.4 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 0.4 GO:0016114 terpenoid biosynthetic process(GO:0016114)
0.1 1.6 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.2 GO:0032382 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373)
0.1 0.2 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.1 0.9 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.5 GO:1990000 amyloid fibril formation(GO:1990000)
0.1 1.2 GO:0007413 axonal fasciculation(GO:0007413)
0.1 0.6 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.5 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.1 1.3 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 2.7 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.1 2.7 GO:0021884 forebrain neuron development(GO:0021884)
0.1 0.4 GO:0016584 nucleosome positioning(GO:0016584)
0.1 2.7 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.0 0.2 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 1.9 GO:0051310 metaphase plate congression(GO:0051310)
0.0 2.1 GO:1901998 toxin transport(GO:1901998)
0.0 0.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.8 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.2 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
0.0 0.1 GO:0015793 glycerol transport(GO:0015793) renal water absorption(GO:0070295)
0.0 0.0 GO:0046544 development of secondary male sexual characteristics(GO:0046544)
0.0 1.1 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.4 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.1 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.0 0.2 GO:0018377 N-terminal protein myristoylation(GO:0006499) protein myristoylation(GO:0018377)
0.0 0.3 GO:0051461 corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.3 GO:1903894 regulation of IRE1-mediated unfolded protein response(GO:1903894)
0.0 0.2 GO:0071356 cellular response to tumor necrosis factor(GO:0071356)
0.0 0.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.8 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 1.4 GO:0007091 metaphase/anaphase transition of mitotic cell cycle(GO:0007091) metaphase/anaphase transition of cell cycle(GO:0044784)
0.0 1.5 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.1 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.0 2.0 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 3.1 GO:0007286 spermatid development(GO:0007286)
0.0 0.8 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.2 GO:0006105 succinate metabolic process(GO:0006105)
0.0 0.2 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 1.3 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.4 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.3 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.1 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700) microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 0.3 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.4 GO:0009081 branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083)
0.0 0.1 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.5 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 1.0 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.3 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.4 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.8 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 1.0 GO:0050679 positive regulation of epithelial cell proliferation(GO:0050679)
0.0 0.5 GO:0006760 folic acid-containing compound metabolic process(GO:0006760)
0.0 0.3 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.4 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.0 3.2 GO:0008360 regulation of cell shape(GO:0008360)
0.0 1.7 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 0.7 GO:1901381 positive regulation of potassium ion transmembrane transport(GO:1901381)
0.0 1.8 GO:0006342 chromatin silencing(GO:0006342)
0.0 1.9 GO:0008033 tRNA processing(GO:0008033)
0.0 0.7 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.0 0.3 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.0 GO:0019062 virion attachment to host cell(GO:0019062) transforming growth factor beta activation(GO:0036363) adhesion of symbiont to host cell(GO:0044650)
0.0 0.1 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.0 0.8 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.5 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.4 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.9 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 4.4 GO:0001525 angiogenesis(GO:0001525)
0.0 0.1 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.4 GO:0006909 phagocytosis(GO:0006909)
0.0 0.2 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.1 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.0 0.5 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 1.0 GO:0006664 glycolipid metabolic process(GO:0006664) liposaccharide metabolic process(GO:1903509)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0071914 prominosome(GO:0071914)
0.5 2.0 GO:0045098 type III intermediate filament(GO:0045098)
0.4 2.7 GO:0001674 female germ cell nucleus(GO:0001674)
0.4 1.2 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.4 2.8 GO:0008278 cohesin complex(GO:0008278)
0.4 3.0 GO:0033269 internode region of axon(GO:0033269)
0.4 1.8 GO:0001533 cornified envelope(GO:0001533)
0.3 10.4 GO:0030904 retromer complex(GO:0030904)
0.3 0.9 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.3 2.3 GO:0001520 outer dense fiber(GO:0001520) meiotic spindle(GO:0072687)
0.3 0.8 GO:0005588 collagen type V trimer(GO:0005588)
0.3 0.5 GO:0000799 nuclear condensin complex(GO:0000799)
0.2 4.7 GO:0031616 spindle pole centrosome(GO:0031616)
0.2 1.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 1.5 GO:0042627 chylomicron(GO:0042627)
0.2 1.6 GO:0005883 neurofilament(GO:0005883)
0.2 1.0 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.2 0.6 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.2 1.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.2 3.8 GO:0045120 pronucleus(GO:0045120)
0.2 0.5 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.6 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.4 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 1.7 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 0.5 GO:1990246 uniplex complex(GO:1990246)
0.1 4.8 GO:0002102 podosome(GO:0002102)
0.1 0.5 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 1.0 GO:0032982 myosin filament(GO:0032982)
0.1 0.9 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 1.1 GO:0005688 U6 snRNP(GO:0005688)
0.1 0.5 GO:0034715 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
0.1 0.5 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.1 0.4 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 5.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 0.7 GO:0030478 actin cap(GO:0030478)
0.1 1.3 GO:0031105 septin complex(GO:0031105)
0.1 0.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 0.9 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 2.8 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 2.0 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 1.2 GO:0045180 basal cortex(GO:0045180)
0.1 1.1 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 0.4 GO:0005687 U4 snRNP(GO:0005687)
0.1 0.7 GO:0042587 glycogen granule(GO:0042587)
0.1 3.6 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 1.1 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.4 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.1 0.4 GO:0032807 DNA ligase IV complex(GO:0032807)
0.1 14.4 GO:0000775 chromosome, centromeric region(GO:0000775)
0.1 0.3 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.7 GO:0016272 prefoldin complex(GO:0016272)
0.1 1.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.2 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 0.5 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.3 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 1.1 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.4 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 2.2 GO:0016592 mediator complex(GO:0016592)
0.1 0.9 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 0.4 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 0.4 GO:0033503 HULC complex(GO:0033503)
0.1 0.2 GO:0060091 kinocilium(GO:0060091)
0.1 0.6 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.4 GO:0005787 signal peptidase complex(GO:0005787)
0.0 1.1 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.5 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 1.7 GO:0032420 stereocilium(GO:0032420)
0.0 15.3 GO:0016607 nuclear speck(GO:0016607)
0.0 1.0 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.4 GO:0097542 ciliary tip(GO:0097542)
0.0 0.3 GO:0035253 ciliary rootlet(GO:0035253)
0.0 1.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.9 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 2.9 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.5 GO:0005838 proteasome regulatory particle(GO:0005838) proteasome accessory complex(GO:0022624)
0.0 1.3 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.6 GO:0031045 dense core granule(GO:0031045)
0.0 2.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 1.1 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 1.5 GO:0005871 kinesin complex(GO:0005871)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.2 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 1.6 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 1.8 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 2.0 GO:0030141 secretory granule(GO:0030141)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.5 GO:0000786 nucleosome(GO:0000786)
0.0 1.4 GO:0005581 collagen trimer(GO:0005581)
0.0 0.3 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.4 GO:0097610 cell division site(GO:0032153) cleavage furrow(GO:0032154) cell division site part(GO:0032155) cell surface furrow(GO:0097610)
0.0 2.3 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.8 GO:0000785 chromatin(GO:0000785)
0.0 0.2 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 5.5 GO:0016604 nuclear body(GO:0016604)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.3 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.9 GO:0031526 brush border membrane(GO:0031526)
0.0 0.8 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.4 GO:0001772 immunological synapse(GO:0001772)
0.0 2.8 GO:0043209 myelin sheath(GO:0043209)
0.0 0.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.9 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.1 GO:0042571 immunoglobulin complex(GO:0019814) immunoglobulin complex, circulating(GO:0042571)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0016015 morphogen activity(GO:0016015)
1.3 3.8 GO:0004962 endothelin receptor activity(GO:0004962)
0.9 2.7 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.8 2.3 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.6 1.7 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.6 6.1 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.5 2.2 GO:0008142 oxysterol binding(GO:0008142)
0.5 1.6 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.5 2.6 GO:0004594 pantothenate kinase activity(GO:0004594)
0.5 2.0 GO:1990254 keratin filament binding(GO:1990254)
0.5 1.4 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.4 1.7 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.3 0.3 GO:0032564 dATP binding(GO:0032564)
0.3 1.5 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.3 2.1 GO:0001849 complement component C1q binding(GO:0001849)
0.3 0.9 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.3 0.8 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.3 1.9 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 3.2 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.2 4.9 GO:0070410 co-SMAD binding(GO:0070410)
0.2 8.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.2 2.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.2 0.8 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.2 0.7 GO:0036468 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
0.2 1.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.2 0.9 GO:1904288 BAT3 complex binding(GO:1904288)
0.2 0.5 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.2 2.0 GO:0031996 thioesterase binding(GO:0031996)
0.2 5.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.9 GO:0016453 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.1 0.6 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 1.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 1.0 GO:0015616 DNA translocase activity(GO:0015616)
0.1 2.9 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 1.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 1.6 GO:0001972 retinoic acid binding(GO:0001972)
0.1 24.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 1.0 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 1.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.4 GO:0070140 isopeptidase activity(GO:0070122) ubiquitin-like protein-specific isopeptidase activity(GO:0070138) SUMO-specific isopeptidase activity(GO:0070140)
0.1 1.3 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.1 0.8 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 3.6 GO:0042805 actinin binding(GO:0042805)
0.1 0.6 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.1 0.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.6 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 0.3 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.1 0.5 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 0.4 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.1 0.4 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 1.3 GO:0035198 miRNA binding(GO:0035198)
0.1 0.7 GO:1901612 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.1 0.5 GO:0017002 activin-activated receptor activity(GO:0017002)
0.1 1.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 6.4 GO:0035064 methylated histone binding(GO:0035064)
0.1 0.5 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.5 GO:0048185 activin binding(GO:0048185)
0.1 1.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 1.3 GO:0030371 translation repressor activity(GO:0030371)
0.1 1.0 GO:0019206 nucleoside kinase activity(GO:0019206)
0.1 0.2 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.1 0.4 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 0.9 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.3 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.1 0.2 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 0.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 1.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.9 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 2.7 GO:0005504 fatty acid binding(GO:0005504)
0.1 1.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.4 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.1 3.2 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.6 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.7 GO:0001618 virus receptor activity(GO:0001618)
0.1 1.2 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.1 0.3 GO:0030911 TPR domain binding(GO:0030911)
0.1 0.4 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1 0.9 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.9 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 5.3 GO:0035326 enhancer binding(GO:0035326)
0.1 2.0 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 0.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 2.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 1.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.9 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.3 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 5.3 GO:0051082 unfolded protein binding(GO:0051082)
0.1 0.4 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 1.0 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.7 GO:0017166 vinculin binding(GO:0017166)
0.0 1.1 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.6 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.6 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 3.7 GO:0042393 histone binding(GO:0042393)
0.0 0.9 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 1.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.5 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 3.8 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.8 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.4 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.0 4.5 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.1 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.7 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171)
0.0 1.0 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.9 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.4 GO:0031386 protein tag(GO:0031386)
0.0 0.3 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 1.1 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 5.5 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 1.4 GO:0097110 scaffold protein binding(GO:0097110)
0.0 5.3 GO:0003779 actin binding(GO:0003779)
0.0 0.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0016708 nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726)
0.0 0.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 2.0 GO:0003777 microtubule motor activity(GO:0003777)
0.0 1.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 11.8 GO:0003682 chromatin binding(GO:0003682)
0.0 0.5 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 3.9 GO:0051015 actin filament binding(GO:0051015)
0.0 0.5 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.2 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 9.1 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 7.0 GO:0045296 cadherin binding(GO:0045296)
0.0 10.8 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 0.4 GO:0043566 structure-specific DNA binding(GO:0043566)
0.0 1.0 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.2 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.4 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.2 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.4 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.3 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 2.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 1.7 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.2 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.4 GO:0005109 frizzled binding(GO:0005109)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.3 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.3 1.3 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.3 5.8 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.2 7.5 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.1 6.0 PID_AURORA_B_PATHWAY Aurora B signaling
0.1 1.0 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.1 4.9 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.1 1.5 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.1 2.5 PID_AURORA_A_PATHWAY Aurora A signaling
0.1 6.8 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 0.8 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.9 PID_IL23_PATHWAY IL23-mediated signaling events
0.0 0.2 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 2.2 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 2.2 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 3.7 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 2.2 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.5 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.0 ST_GAQ_PATHWAY G alpha q Pathway
0.0 1.4 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 1.6 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 1.1 PID_FAS_PATHWAY FAS (CD95) signaling pathway
0.0 0.9 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.6 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.8 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 1.1 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.5 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 1.4 ST_INTEGRIN_SIGNALING_PATHWAY Integrin Signaling Pathway
0.0 0.2 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.9 PID_PLK1_PATHWAY PLK1 signaling events
0.0 0.2 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.0 0.5 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.4 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
0.0 0.5 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 1.8 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 0.4 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.1 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.3 5.9 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.3 6.6 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.2 4.1 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.2 2.9 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.2 10.4 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.2 1.3 REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.2 2.6 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.2 4.9 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 2.3 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.1 3.0 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 2.4 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 2.6 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 0.2 REACTOME_DOWNSTREAM_TCR_SIGNALING Genes involved in Downstream TCR signaling
0.1 1.5 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 2.4 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1 0.9 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 1.2 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 6.5 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 0.8 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.1 4.1 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.1 0.7 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.1 2.7 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 4.0 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.7 REACTOME_KINESINS Genes involved in Kinesins
0.1 1.0 REACTOME_KERATAN_SULFATE_BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 1.0 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.1 0.6 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 0.8 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 1.8 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.1 2.9 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 1.0 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.4 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.0 0.3 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.8 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 1.0 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 3.2 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.3 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.8 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.6 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 1.7 REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 2.9 REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.4 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.7 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.4 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.0 0.5 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.2 REACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM Genes involved in Bile acid and bile salt metabolism
0.0 0.7 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.7 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.2 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.2 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.1 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 2.8 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.2 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.0 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.4 REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.2 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.5 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.2 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.5 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)