Motif ID: Hsf2

Z-value: 1.780


Transcription factors associated with Hsf2:

Gene SymbolEntrez IDGene Name
Hsf2 ENSMUSG00000019878.7 Hsf2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hsf2mm10_v2_chr10_+_57486354_57486414-0.287.2e-02Click!


Activity profile for motif Hsf2.

activity profile for motif Hsf2


Sorted Z-values histogram for motif Hsf2

Sorted Z-values for motif Hsf2



Network of associatons between targets according to the STRING database.



First level regulatory network of Hsf2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_154960915 11.349 ENSMUST00000049621.6
Hes5
hairy and enhancer of split 5 (Drosophila)
chr17_-_25797032 10.534 ENSMUST00000165838.1
ENSMUST00000002344.6
Metrn

meteorin, glial cell differentiation regulator

chr10_+_4710119 10.303 ENSMUST00000105588.1
ENSMUST00000105589.1
Esr1

estrogen receptor 1 (alpha)

chr10_-_78591945 9.560 ENSMUST00000040580.6
Syde1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr9_+_44134562 9.498 ENSMUST00000034650.8
ENSMUST00000098852.2
Mcam

melanoma cell adhesion molecule

chr10_+_84838143 9.229 ENSMUST00000095388.4
Rfx4
regulatory factor X, 4 (influences HLA class II expression)
chr11_-_89302545 9.028 ENSMUST00000061728.3
Nog
noggin
chr1_-_72874877 8.911 ENSMUST00000027377.8
Igfbp5
insulin-like growth factor binding protein 5
chr17_-_70851189 8.857 ENSMUST00000059775.8
Tgif1
TGFB-induced factor homeobox 1
chr18_-_80986578 8.364 ENSMUST00000057950.7
Sall3
sal-like 3 (Drosophila)
chr17_-_70849644 8.233 ENSMUST00000134654.1
ENSMUST00000172229.1
ENSMUST00000127719.1
Tgif1


TGFB-induced factor homeobox 1


chr12_-_91746020 7.314 ENSMUST00000166967.1
Ston2
stonin 2
chr11_-_11970540 7.121 ENSMUST00000109653.1
Grb10
growth factor receptor bound protein 10
chr1_-_133424377 6.849 ENSMUST00000153799.1
Sox13
SRY-box containing gene 13
chr10_-_92164666 6.796 ENSMUST00000183123.1
ENSMUST00000182033.1
Rmst

rhabdomyosarcoma 2 associated transcript (non-coding RNA)

chr7_+_16781341 6.486 ENSMUST00000108496.2
Slc1a5
solute carrier family 1 (neutral amino acid transporter), member 5
chr5_-_5514730 6.333 ENSMUST00000115445.1
ENSMUST00000179804.1
ENSMUST00000125110.1
ENSMUST00000115446.1
Cldn12



claudin 12



chr9_+_7764041 6.298 ENSMUST00000052865.9
Tmem123
transmembrane protein 123
chr14_-_48667508 6.143 ENSMUST00000144465.1
ENSMUST00000133479.1
ENSMUST00000119070.1
ENSMUST00000152018.1
Otx2



orthodenticle homolog 2 (Drosophila)



chr6_-_92943485 6.137 ENSMUST00000113438.1
Adamts9
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 9
chr5_-_5514873 6.082 ENSMUST00000060947.7
Cldn12
claudin 12
chr10_+_121033960 6.058 ENSMUST00000020439.4
ENSMUST00000175867.1
Wif1

Wnt inhibitory factor 1

chr13_+_51645232 5.868 ENSMUST00000075853.5
Cks2
CDC28 protein kinase regulatory subunit 2
chr3_+_27984145 5.780 ENSMUST00000067757.4
Pld1
phospholipase D1
chr9_-_100571049 5.772 ENSMUST00000093792.2
Slc35g2
solute carrier family 35, member G2
chr11_+_120949053 5.646 ENSMUST00000154187.1
ENSMUST00000100130.3
ENSMUST00000129473.1
ENSMUST00000168579.1
Slc16a3



solute carrier family 16 (monocarboxylic acid transporters), member 3



chr2_+_25180737 5.584 ENSMUST00000104999.2
Nrarp
Notch-regulated ankyrin repeat protein
chr18_+_50053282 5.410 ENSMUST00000148159.2
Tnfaip8
tumor necrosis factor, alpha-induced protein 8
chr7_-_25250720 5.316 ENSMUST00000116343.2
ENSMUST00000045847.8
Erf

Ets2 repressor factor

chr7_-_110061319 5.252 ENSMUST00000098110.2
AA474408
expressed sequence AA474408
chr17_-_58991343 5.191 ENSMUST00000025064.7
2610034M16Rik
RIKEN cDNA 2610034M16 gene
chr11_+_26387194 5.172 ENSMUST00000109509.1
ENSMUST00000136830.1
Fancl

Fanconi anemia, complementation group L

chr7_-_4752972 5.168 ENSMUST00000183971.1
ENSMUST00000182173.1
ENSMUST00000182738.1
ENSMUST00000184143.1
ENSMUST00000182111.1
ENSMUST00000182048.1
ENSMUST00000063324.7
Cox6b2






cytochrome c oxidase subunit VIb polypeptide 2






chr2_+_52038005 5.155 ENSMUST00000065927.5
Tnfaip6
tumor necrosis factor alpha induced protein 6
chr2_+_30061754 5.080 ENSMUST00000149578.1
ENSMUST00000102866.3
Set

SET nuclear oncogene

chr6_-_95718800 4.997 ENSMUST00000079847.5
Suclg2
succinate-Coenzyme A ligase, GDP-forming, beta subunit
chr12_-_10900296 4.994 ENSMUST00000085735.2
Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chr2_+_30845059 4.881 ENSMUST00000041659.5
Prrx2
paired related homeobox 2
chr2_+_91256144 4.866 ENSMUST00000154959.1
ENSMUST00000059566.4
Pacsin3

protein kinase C and casein kinase substrate in neurons 3

chr9_-_114781986 4.792 ENSMUST00000035009.8
ENSMUST00000084867.7
Cmtm7

CKLF-like MARVEL transmembrane domain containing 7

chr17_-_15375969 4.783 ENSMUST00000014917.7
Dll1
delta-like 1 (Drosophila)
chr2_+_71389239 4.756 ENSMUST00000028408.2
Hat1
histone aminotransferase 1
chr12_-_69228167 4.670 ENSMUST00000021359.5
Pole2
polymerase (DNA directed), epsilon 2 (p59 subunit)
chr6_+_56832059 4.668 ENSMUST00000031795.7
Fkbp9
FK506 binding protein 9
chr6_-_72235559 4.650 ENSMUST00000042646.7
Atoh8
atonal homolog 8 (Drosophila)
chr7_-_19310035 4.637 ENSMUST00000003640.2
Fosb
FBJ osteosarcoma oncogene B
chr5_-_100820929 4.608 ENSMUST00000117364.1
ENSMUST00000055245.6
Fam175a

family with sequence similarity 175, member A

chr19_-_10203880 4.569 ENSMUST00000142241.1
ENSMUST00000116542.2
ENSMUST00000025651.5
ENSMUST00000156291.1
Fen1



flap structure specific endonuclease 1



chr12_-_56536895 4.562 ENSMUST00000001536.8
Nkx2-1
NK2 homeobox 1
chr14_+_19751257 4.459 ENSMUST00000022340.3
Nid2
nidogen 2
chr15_-_8710734 4.424 ENSMUST00000005493.7
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr6_-_119467210 4.306 ENSMUST00000118120.1
Wnt5b
wingless-related MMTV integration site 5B
chr10_+_128238034 4.260 ENSMUST00000105245.2
Timeless
timeless circadian clock 1
chr2_+_91255954 4.228 ENSMUST00000134699.1
Pacsin3
protein kinase C and casein kinase substrate in neurons 3
chr2_+_59612034 4.151 ENSMUST00000112568.1
ENSMUST00000037526.4
Tanc1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr5_+_92683625 4.102 ENSMUST00000168878.1
Shroom3
shroom family member 3
chr17_-_70851710 4.086 ENSMUST00000166395.2
Tgif1
TGFB-induced factor homeobox 1
chr1_+_136467958 4.069 ENSMUST00000047817.6
Kif14
kinesin family member 14
chr19_+_25505618 4.064 ENSMUST00000025755.4
Dmrt1
doublesex and mab-3 related transcription factor 1
chr2_-_26503814 4.003 ENSMUST00000028288.4
Notch1
notch 1
chr15_+_78926720 3.938 ENSMUST00000089377.5
Lgals1
lectin, galactose binding, soluble 1
chr5_+_92603039 3.913 ENSMUST00000050952.3
Stbd1
starch binding domain 1
chr18_-_53418004 3.859 ENSMUST00000025419.7
Ppic
peptidylprolyl isomerase C
chrX_-_75843063 3.817 ENSMUST00000114057.1
Pls3
plastin 3 (T-isoform)
chr7_+_127211608 3.728 ENSMUST00000032910.6
Mylpf
myosin light chain, phosphorylatable, fast skeletal muscle
chr7_-_99353104 3.724 ENSMUST00000169437.1
ENSMUST00000094154.4
Serpinh1

serine (or cysteine) peptidase inhibitor, clade H, member 1

chr2_+_152847961 3.716 ENSMUST00000164120.1
ENSMUST00000178997.1
ENSMUST00000109816.1
Tpx2


TPX2, microtubule-associated protein homolog (Xenopus laevis)


chr4_-_41695442 3.690 ENSMUST00000102961.3
ENSMUST00000064443.6
Cntfr

ciliary neurotrophic factor receptor

chr9_-_77544870 3.651 ENSMUST00000183873.1
Lrrc1
leucine rich repeat containing 1
chr17_+_47593516 3.649 ENSMUST00000182874.1
Ccnd3
cyclin D3
chr17_+_47593444 3.634 ENSMUST00000182209.1
Ccnd3
cyclin D3
chr2_+_152847993 3.628 ENSMUST00000028969.8
Tpx2
TPX2, microtubule-associated protein homolog (Xenopus laevis)
chr5_-_116422858 3.570 ENSMUST00000036991.4
Hspb8
heat shock protein 8
chr9_-_97018823 3.490 ENSMUST00000055433.4
Spsb4
splA/ryanodine receptor domain and SOCS box containing 4
chr13_-_3918157 3.457 ENSMUST00000091853.4
Net1
neuroepithelial cell transforming gene 1
chr8_+_15011025 3.360 ENSMUST00000069399.6
Kbtbd11
kelch repeat and BTB (POZ) domain containing 11
chr4_-_147936713 3.318 ENSMUST00000105712.1
ENSMUST00000019199.7
Plod1

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1

chrX_+_56779699 3.285 ENSMUST00000114772.2
ENSMUST00000114768.3
ENSMUST00000155882.1
Fhl1


four and a half LIM domains 1


chr6_+_53573364 3.270 ENSMUST00000047450.7
Creb5
cAMP responsive element binding protein 5
chr6_-_128438673 3.253 ENSMUST00000032508.4
Fkbp4
FK506 binding protein 4
chr1_-_17097839 3.188 ENSMUST00000038382.4
Jph1
junctophilin 1
chr3_+_68869563 3.172 ENSMUST00000054551.2
1110032F04Rik
RIKEN cDNA 1110032F04 gene
chr5_+_7179299 3.119 ENSMUST00000179460.1
Tubb4b-ps1
tubulin, beta 4B class IVB, pseudogene 1
chr10_-_23349887 3.090 ENSMUST00000074366.6
ENSMUST00000092665.4
Eya4

eyes absent 4 homolog (Drosophila)

chr9_+_15520830 3.080 ENSMUST00000178999.1
Smco4
single-pass membrane protein with coiled-coil domains 4
chr5_-_129787175 3.047 ENSMUST00000031399.6
Psph
phosphoserine phosphatase
chr9_+_72438519 3.046 ENSMUST00000184604.1
Mns1
meiosis-specific nuclear structural protein 1
chr2_-_172370506 3.014 ENSMUST00000109139.1
ENSMUST00000028997.7
ENSMUST00000109140.3
Aurka


aurora kinase A


chr3_+_94342092 2.994 ENSMUST00000029794.5
Them5
thioesterase superfamily member 5
chr14_-_65833963 2.979 ENSMUST00000022613.9
Esco2
establishment of cohesion 1 homolog 2 (S. cerevisiae)
chr4_+_62965560 2.961 ENSMUST00000030043.6
ENSMUST00000107415.1
ENSMUST00000064814.5
Zfp618


zinc finger protein 618


chr5_-_137116177 2.936 ENSMUST00000054384.5
ENSMUST00000152207.1
Trim56

tripartite motif-containing 56

chr15_+_25773985 2.910 ENSMUST00000125667.1
Myo10
myosin X
chr2_-_28466266 2.791 ENSMUST00000127683.1
ENSMUST00000086370.4
1700007K13Rik

RIKEN cDNA 1700007K13 gene

chrX_+_56779437 2.785 ENSMUST00000114773.3
Fhl1
four and a half LIM domains 1
chr9_-_77544829 2.772 ENSMUST00000183734.1
Lrrc1
leucine rich repeat containing 1
chr1_-_55088024 2.760 ENSMUST00000027123.8
Hspd1
heat shock protein 1 (chaperonin)
chr10_-_80421847 2.739 ENSMUST00000156244.1
Tcf3
transcription factor 3
chr11_+_43528759 2.719 ENSMUST00000050574.6
Ccnjl
cyclin J-like
chr1_-_119053619 2.715 ENSMUST00000062483.8
Gli2
GLI-Kruppel family member GLI2
chr6_+_72598475 2.690 ENSMUST00000070597.6
ENSMUST00000176364.1
ENSMUST00000176168.1
Retsat


retinol saturase (all trans retinol 13,14 reductase)


chr5_-_50058908 2.649 ENSMUST00000030971.5
Gpr125
G protein-coupled receptor 125
chr5_-_149636164 2.603 ENSMUST00000076410.4
Hsph1
heat shock 105kDa/110kDa protein 1
chr11_-_115813621 2.598 ENSMUST00000041684.4
ENSMUST00000156812.1
Caskin2

CASK-interacting protein 2

chr11_+_115564434 2.591 ENSMUST00000021085.4
Nup85
nucleoporin 85
chr1_-_44101661 2.574 ENSMUST00000152239.1
Tex30
testis expressed 30
chr8_+_95633500 2.563 ENSMUST00000034094.9
Gins3
GINS complex subunit 3 (Psf3 homolog)
chr6_+_134929089 2.547 ENSMUST00000183867.1
ENSMUST00000184991.1
ENSMUST00000183905.1
RP23-45G16.5


RP23-45G16.5


chr5_-_149051604 2.517 ENSMUST00000093196.4
Hmgb1
high mobility group box 1
chr2_-_57113053 2.479 ENSMUST00000112627.1
Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr4_+_105790534 2.474 ENSMUST00000185012.1
Gm12728
predicted gene 12728
chr13_-_102958084 2.456 ENSMUST00000099202.3
ENSMUST00000172264.1
Mast4

microtubule associated serine/threonine kinase family member 4

chr6_+_128438757 2.441 ENSMUST00000144745.1
Gm10069
predicted gene 10069
chr2_+_130277157 2.430 ENSMUST00000028890.8
ENSMUST00000159373.1
Nop56

NOP56 ribonucleoprotein

chr4_-_154097105 2.378 ENSMUST00000105643.1
ENSMUST00000133533.1
ENSMUST00000097762.4
Trp73


transformation related protein 73


chr2_-_91931696 2.368 ENSMUST00000090602.5
Mdk
midkine
chr2_-_91931675 2.349 ENSMUST00000111309.1
Mdk
midkine
chr4_+_150236685 2.338 ENSMUST00000150175.1
Eno1
enolase 1, alpha non-neuron
chr17_-_25727364 2.312 ENSMUST00000170070.1
ENSMUST00000048054.7
Chtf18

CTF18, chromosome transmission fidelity factor 18

chr7_-_127286385 2.286 ENSMUST00000172206.2
Gm17511
predicted gene, 17511
chr7_-_140102384 2.273 ENSMUST00000120034.1
ENSMUST00000121115.1
ENSMUST00000026539.7
Fuom


fucose mutarotase


chr18_-_61259987 2.271 ENSMUST00000170335.2
Rps2-ps10
ribosomal protein S2, pseudogene 10
chr6_-_21852509 2.260 ENSMUST00000031678.3
Tspan12
tetraspanin 12
chr1_+_95313607 2.250 ENSMUST00000059975.6
Fam174a
family with sequence similarity 174, member A
chr2_-_26246707 2.250 ENSMUST00000166349.1
C030048H21Rik
RIKEN cDNA C030048H21 gene
chr16_-_45844303 2.215 ENSMUST00000036355.6
Phldb2
pleckstrin homology-like domain, family B, member 2
chr7_-_118995211 2.209 ENSMUST00000008878.8
Gprc5b
G protein-coupled receptor, family C, group 5, member B
chr7_-_120982260 2.198 ENSMUST00000033169.8
Cdr2
cerebellar degeneration-related 2
chr16_-_45844228 2.192 ENSMUST00000076333.5
Phldb2
pleckstrin homology-like domain, family B, member 2
chr4_+_141242850 2.170 ENSMUST00000138096.1
ENSMUST00000006618.2
ENSMUST00000125392.1
Arhgef19


Rho guanine nucleotide exchange factor (GEF) 19


chr6_-_21851914 2.168 ENSMUST00000134635.1
ENSMUST00000123116.1
ENSMUST00000120965.1
Tspan12


tetraspanin 12


chr17_+_47505149 2.141 ENSMUST00000183177.1
ENSMUST00000182848.1
Ccnd3

cyclin D3

chr4_-_116708312 2.139 ENSMUST00000030453.4
Mmachc
methylmalonic aciduria cblC type, with homocystinuria
chr6_-_76497631 2.118 ENSMUST00000097218.5
Gm9008
predicted pseudogene 9008
chr2_-_151039363 2.106 ENSMUST00000066640.4
ENSMUST00000128627.1
Nanp
Ninl
N-acetylneuraminic acid phosphatase
ninein-like
chr1_-_136234113 2.078 ENSMUST00000120339.1
ENSMUST00000048668.8
5730559C18Rik

RIKEN cDNA 5730559C18 gene

chr4_-_43030440 2.037 ENSMUST00000135660.1
Stoml2
stomatin (Epb7.2)-like 2
chr3_+_24333046 2.023 ENSMUST00000077389.6
Gm7536
predicted gene 7536
chr4_-_107923519 2.020 ENSMUST00000106719.1
ENSMUST00000106720.2
ENSMUST00000131644.1
ENSMUST00000030345.8
Cpt2



carnitine palmitoyltransferase 2



chr10_-_81349085 1.997 ENSMUST00000141171.1
Hmg20b
high mobility group 20B
chr19_+_53903351 1.979 ENSMUST00000025931.6
ENSMUST00000165617.1
Pdcd4

programmed cell death 4

chr18_+_60925644 1.948 ENSMUST00000115297.1
Camk2a
calcium/calmodulin-dependent protein kinase II alpha
chr10_-_92165159 1.909 ENSMUST00000182567.1
ENSMUST00000181604.2
ENSMUST00000181213.1
Rmst


rhabdomyosarcoma 2 associated transcript (non-coding RNA)


chr17_+_47505211 1.908 ENSMUST00000182935.1
ENSMUST00000182506.1
Ccnd3

cyclin D3

chr9_-_44113470 1.896 ENSMUST00000056328.5
Rnf26
ring finger protein 26
chr6_+_66896397 1.884 ENSMUST00000043148.6
ENSMUST00000114228.1
ENSMUST00000114227.1
ENSMUST00000114226.1
ENSMUST00000114225.1
ENSMUST00000114224.1
Gng12





guanine nucleotide binding protein (G protein), gamma 12





chr1_-_121567906 1.884 ENSMUST00000001724.5
Ddx18
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr4_+_128883549 1.864 ENSMUST00000035667.8
Trim62
tripartite motif-containing 62
chr12_-_84218835 1.860 ENSMUST00000046266.6
Elmsan1
ELM2 and Myb/SANT-like domain containing 1
chr1_+_12692430 1.839 ENSMUST00000180062.1
ENSMUST00000177608.1
Sulf1

sulfatase 1

chr2_-_149798701 1.830 ENSMUST00000148202.1
ENSMUST00000139471.1
Gm14133

predicted gene 14133

chr10_+_80826656 1.827 ENSMUST00000060987.8
ENSMUST00000177850.1
ENSMUST00000180036.1
ENSMUST00000179172.1
Oaz1



ornithine decarboxylase antizyme 1



chr5_+_30105161 1.821 ENSMUST00000058045.4
Gareml
GRB2 associated, regulator of MAPK1-like
chr5_+_32611171 1.802 ENSMUST00000072311.6
ENSMUST00000168707.2
Yes1

Yamaguchi sarcoma viral (v-yes) oncogene homolog 1

chr3_+_125404072 1.794 ENSMUST00000173932.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr7_-_44815658 1.787 ENSMUST00000107893.1
Atf5
activating transcription factor 5
chr18_-_84681966 1.778 ENSMUST00000168419.1
Cndp2
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr1_+_131867224 1.776 ENSMUST00000112386.1
ENSMUST00000027693.7
Rab7l1

RAB7, member RAS oncogene family-like 1

chr4_+_59626189 1.763 ENSMUST00000070150.4
ENSMUST00000052420.6
E130308A19Rik

RIKEN cDNA E130308A19 gene

chr1_-_138847579 1.725 ENSMUST00000093486.3
ENSMUST00000046870.6
Lhx9

LIM homeobox protein 9

chr2_-_157135112 1.724 ENSMUST00000139263.1
Samhd1
SAM domain and HD domain, 1
chr2_+_29889785 1.709 ENSMUST00000113763.1
ENSMUST00000113757.1
ENSMUST00000113756.1
ENSMUST00000133233.1
ENSMUST00000113759.2
ENSMUST00000113755.1
ENSMUST00000137558.1
ENSMUST00000046571.7
Odf2







outer dense fiber of sperm tails 2







chr2_+_31759932 1.699 ENSMUST00000028190.6
Abl1
c-abl oncogene 1, non-receptor tyrosine kinase
chr19_+_6363896 1.687 ENSMUST00000113487.1
Sf1
splicing factor 1
chr2_+_120463566 1.684 ENSMUST00000028749.7
ENSMUST00000110721.1
Capn3

calpain 3

chr6_+_134035691 1.678 ENSMUST00000081028.6
ENSMUST00000111963.1
Etv6

ets variant gene 6 (TEL oncogene)

chr19_-_6057736 1.676 ENSMUST00000007482.6
Mrpl49
mitochondrial ribosomal protein L49
chr11_+_100415697 1.675 ENSMUST00000001595.3
Fkbp10
FK506 binding protein 10
chr7_+_128265675 1.671 ENSMUST00000118169.1
ENSMUST00000142841.1
Slc5a2

solute carrier family 5 (sodium/glucose cotransporter), member 2

chr5_-_23783700 1.666 ENSMUST00000119946.1
Pus7
pseudouridylate synthase 7 homolog (S. cerevisiae)
chr2_+_115581667 1.665 ENSMUST00000166472.1
ENSMUST00000110918.2
BC052040

cDNA sequence BC052040

chr18_-_47368446 1.638 ENSMUST00000076043.6
ENSMUST00000135790.1
Sema6a

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A

chr5_-_5694024 1.632 ENSMUST00000115425.2
ENSMUST00000115427.1
ENSMUST00000115424.2
ENSMUST00000015797.4
Steap2



six transmembrane epithelial antigen of prostate 2



chr6_+_65381294 1.620 ENSMUST00000170608.1
C130060K24Rik
RIKEN cDNA C130060K24 gene
chr7_+_75610038 1.619 ENSMUST00000125771.1
Akap13
A kinase (PRKA) anchor protein 13
chr1_-_193273099 1.618 ENSMUST00000009777.2
G0s2
G0/G1 switch gene 2
chr17_-_34627148 1.615 ENSMUST00000171376.1
ENSMUST00000169287.1
Ppt2

palmitoyl-protein thioesterase 2

chr6_+_82041623 1.614 ENSMUST00000042974.8
Eva1a
eva-1 homolog A (C. elegans)
chrX_-_51205773 1.612 ENSMUST00000114875.1
Mbnl3
muscleblind-like 3 (Drosophila)
chr16_+_13358375 1.591 ENSMUST00000149359.1
Mkl2
MKL/myocardin-like 2
chr2_-_181691771 1.580 ENSMUST00000108778.1
ENSMUST00000165416.1
Rgs19

regulator of G-protein signaling 19

chr8_+_92357787 1.571 ENSMUST00000034184.10
Irx5
Iroquois related homeobox 5 (Drosophila)
chr13_-_97760588 1.569 ENSMUST00000074072.3
Gm10260
predicted gene 10260
chr9_+_66126611 1.546 ENSMUST00000034945.5
Fam96a
family with sequence similarity 96, member A
chr19_+_6363719 1.536 ENSMUST00000113489.1
ENSMUST00000113488.1
Sf1

splicing factor 1

chr4_-_86669492 1.535 ENSMUST00000149700.1
Plin2
perilipin 2
chr11_+_53770458 1.509 ENSMUST00000138913.1
ENSMUST00000123376.1
ENSMUST00000019043.6
ENSMUST00000133291.1
Irf1



interferon regulatory factor 1



chr1_+_178798438 1.502 ENSMUST00000160789.1
Kif26b
kinesin family member 26B
chr11_+_34314757 1.501 ENSMUST00000165963.1
ENSMUST00000093192.3
Fam196b

family with sequence similarity 196, member B

chr19_-_60874526 1.500 ENSMUST00000025961.6
Prdx3
peroxiredoxin 3
chr2_+_158624882 1.498 ENSMUST00000045644.8
Actr5
ARP5 actin-related protein 5
chr1_-_45503282 1.490 ENSMUST00000086430.4
Col5a2
collagen, type V, alpha 2
chr2_+_29889720 1.477 ENSMUST00000113767.1
Odf2
outer dense fiber of sperm tails 2
chr5_+_76183880 1.468 ENSMUST00000031144.7
Tmem165
transmembrane protein 165
chr17_-_28517509 1.460 ENSMUST00000114792.1
ENSMUST00000177939.1
Fkbp5

FK506 binding protein 5

chr10_-_81266906 1.453 ENSMUST00000046114.4
Mrpl54
mitochondrial ribosomal protein L54
chr17_+_36958571 1.447 ENSMUST00000040177.6
Znrd1as
Znrd1 antisense
chr1_-_79858627 1.441 ENSMUST00000027467.4
Serpine2
serine (or cysteine) peptidase inhibitor, clade E, member 2
chr16_-_56024628 1.433 ENSMUST00000119981.1
ENSMUST00000096021.3
Pcnp

PEST proteolytic signal containing nuclear protein

chr10_-_67912620 1.429 ENSMUST00000064656.7
Zfp365
zinc finger protein 365

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 20.1 GO:2000981 negative regulation of mechanoreceptor differentiation(GO:0045632) negative regulation of inner ear receptor cell differentiation(GO:2000981)
2.6 10.3 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
2.3 9.0 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
1.9 9.6 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
1.8 9.2 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
1.6 4.7 GO:0030421 defecation(GO:0030421)
1.5 6.1 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
1.5 4.6 GO:0021759 globus pallidus development(GO:0021759)
1.5 6.0 GO:0015825 L-serine transport(GO:0015825)
1.4 4.3 GO:1904975 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
1.4 4.1 GO:0021698 cerebellar cortex structural organization(GO:0021698)
1.3 21.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
1.3 8.9 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
1.2 4.8 GO:0002337 B-1a B cell differentiation(GO:0002337)
1.1 3.4 GO:0002842 positive regulation of T cell mediated immune response to tumor cell(GO:0002842) protein import into mitochondrial intermembrane space(GO:0045041)
1.1 4.4 GO:0043490 malate-aspartate shuttle(GO:0043490)
1.1 5.3 GO:0010668 ectodermal cell differentiation(GO:0010668)
1.0 3.1 GO:1900275 B cell proliferation involved in immune response(GO:0002322) negative regulation of phospholipase C activity(GO:1900275)
0.9 3.7 GO:0003360 brainstem development(GO:0003360)
0.9 3.7 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345) positive regulation of NK T cell activation(GO:0051135)
0.9 2.6 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.8 2.5 GO:0045819 plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819)
0.8 3.3 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.8 5.8 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.8 7.1 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.8 4.6 GO:0043137 DNA replication, removal of RNA primer(GO:0043137) positive regulation of sister chromatid cohesion(GO:0045876)
0.8 3.0 GO:0007056 spindle assembly involved in female meiosis(GO:0007056) positive regulation of oocyte development(GO:0060282)
0.7 2.0 GO:1990046 positive regulation of mitochondrial DNA replication(GO:0090297) regulation of cardiolipin metabolic process(GO:1900208) positive regulation of cardiolipin metabolic process(GO:1900210) stress-induced mitochondrial fusion(GO:1990046)
0.7 2.7 GO:0060032 notochord regression(GO:0060032)
0.7 4.1 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.7 2.0 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.7 3.9 GO:0002317 plasma cell differentiation(GO:0002317) positive regulation of viral entry into host cell(GO:0046598)
0.6 9.7 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.6 4.4 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.6 2.5 GO:0051866 general adaptation syndrome(GO:0051866)
0.6 6.1 GO:1902913 positive regulation of melanocyte differentiation(GO:0045636) positive regulation of neuroepithelial cell differentiation(GO:1902913)
0.6 3.0 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.6 3.0 GO:0034421 post-translational protein acetylation(GO:0034421)
0.6 2.4 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.6 1.8 GO:0019043 establishment of viral latency(GO:0019043)
0.6 7.7 GO:0046643 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.6 4.7 GO:0014807 regulation of somitogenesis(GO:0014807)
0.6 5.6 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.6 1.7 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.6 5.0 GO:0006105 succinyl-CoA metabolic process(GO:0006104) succinate metabolic process(GO:0006105)
0.5 2.7 GO:0002326 B cell lineage commitment(GO:0002326)
0.5 4.8 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.5 1.5 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) negative regulation of regulatory T cell differentiation(GO:0045590) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.5 9.6 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.5 1.5 GO:0072092 ureteric bud invasion(GO:0072092)
0.5 3.0 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.5 1.5 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.5 1.4 GO:0033566 gamma-tubulin complex localization(GO:0033566)
0.5 1.8 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.5 1.8 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.4 1.3 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.4 12.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.4 1.7 GO:0035262 gonad morphogenesis(GO:0035262)
0.4 1.7 GO:0006203 dGTP catabolic process(GO:0006203) dATP catabolic process(GO:0046061)
0.4 2.6 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.4 2.1 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
0.4 0.8 GO:0072076 nephrogenic mesenchyme development(GO:0072076)
0.4 9.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.4 0.8 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.4 3.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.4 2.7 GO:0042572 retinol metabolic process(GO:0042572)
0.4 1.1 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.4 2.2 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.4 1.8 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.4 1.4 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.4 7.9 GO:0045793 positive regulation of cell size(GO:0045793)
0.4 2.5 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.3 2.1 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.3 4.4 GO:0030238 male sex determination(GO:0030238)
0.3 1.7 GO:1904659 glucose transmembrane transport(GO:1904659)
0.3 1.6 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.3 1.6 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.3 1.0 GO:1903054 protein targeting to vacuole involved in autophagy(GO:0071211) lysosomal membrane organization(GO:0097212) negative regulation of extracellular matrix organization(GO:1903054) positive regulation of protein folding(GO:1903334)
0.3 1.6 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.3 4.6 GO:0051639 actin filament network formation(GO:0051639)
0.3 1.5 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.3 4.6 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.3 2.3 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.3 0.9 GO:0002946 tRNA C5-cytosine methylation(GO:0002946)
0.3 2.3 GO:0006004 fucose metabolic process(GO:0006004)
0.3 3.7 GO:0051451 myoblast migration(GO:0051451)
0.3 0.6 GO:0001803 antibody-dependent cellular cytotoxicity(GO:0001788) type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.3 0.8 GO:1904154 protein localization to endoplasmic reticulum exit site(GO:0070973) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.3 0.8 GO:1903984 regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.3 1.6 GO:0046349 amino sugar biosynthetic process(GO:0046349)
0.3 3.0 GO:0032048 cardiolipin metabolic process(GO:0032048)
0.3 1.1 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.3 0.5 GO:0002489 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489)
0.3 1.0 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.3 3.0 GO:0070986 left/right axis specification(GO:0070986)
0.2 1.0 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.2 3.9 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.2 2.3 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.2 4.8 GO:0046596 regulation of viral entry into host cell(GO:0046596)
0.2 1.1 GO:0003420 regulation of growth plate cartilage chondrocyte proliferation(GO:0003420)
0.2 2.4 GO:0006228 UTP biosynthetic process(GO:0006228)
0.2 1.8 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.2 0.8 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.2 2.0 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.2 0.8 GO:0033580 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
0.2 1.3 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.2 0.6 GO:0006597 spermine biosynthetic process(GO:0006597)
0.2 0.6 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.2 10.1 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.2 1.2 GO:0007296 vitellogenesis(GO:0007296)
0.2 0.5 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.2 1.9 GO:1990173 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.2 0.5 GO:0097026 myeloid dendritic cell chemotaxis(GO:0002408) dendritic cell dendrite assembly(GO:0097026) mature conventional dendritic cell differentiation(GO:0097029)
0.2 0.3 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.2 6.1 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) negative regulation of cell cycle G2/M phase transition(GO:1902750)
0.2 2.9 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.2 1.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.2 4.4 GO:0010842 retina layer formation(GO:0010842)
0.2 1.8 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.1 1.9 GO:0099628 angiotensin-activated signaling pathway(GO:0038166) receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.1 4.2 GO:0007520 myoblast fusion(GO:0007520)
0.1 1.0 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.7 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.1 1.0 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 2.7 GO:0042474 middle ear morphogenesis(GO:0042474)
0.1 1.1 GO:0071285 cellular response to lithium ion(GO:0071285)
0.1 4.8 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.1 0.5 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 1.3 GO:0002176 male germ cell proliferation(GO:0002176)
0.1 6.7 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.1 0.5 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 3.1 GO:0000154 rRNA modification(GO:0000154)
0.1 2.8 GO:0001522 pseudouridine synthesis(GO:0001522)
0.1 0.3 GO:0016925 protein sumoylation(GO:0016925)
0.1 0.8 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.1 0.4 GO:0007113 endomitotic cell cycle(GO:0007113)
0.1 1.5 GO:0070914 UV-damage excision repair(GO:0070914)
0.1 0.3 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.1 1.9 GO:0050687 negative regulation of defense response to virus(GO:0050687)
0.1 0.7 GO:0034770 histone H4-K20 methylation(GO:0034770)
0.1 0.6 GO:0006458 'de novo' protein folding(GO:0006458)
0.1 0.1 GO:0019433 triglyceride catabolic process(GO:0019433)
0.1 1.6 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.1 0.9 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.7 GO:0098535 de novo centriole assembly(GO:0098535)
0.1 0.4 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.1 1.2 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.5 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.1 2.6 GO:0048246 macrophage chemotaxis(GO:0048246)
0.1 0.3 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.1 1.0 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation(GO:0050731)
0.1 0.5 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.1 0.2 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.1 3.3 GO:0060612 adipose tissue development(GO:0060612)
0.1 0.2 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.1 0.8 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 0.4 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.1 0.6 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.1 1.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 4.6 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.1 0.7 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.9 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 3.9 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 0.5 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 1.0 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.1 0.7 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1 0.6 GO:0040016 embryonic cleavage(GO:0040016)
0.1 3.6 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.1 3.5 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.1 0.4 GO:0044241 lipid digestion(GO:0044241)
0.1 3.3 GO:0050830 defense response to Gram-positive bacterium(GO:0050830)
0.1 0.2 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.1 0.4 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.1 1.2 GO:0045116 protein neddylation(GO:0045116)
0.1 0.2 GO:0006710 androgen catabolic process(GO:0006710)
0.1 0.3 GO:0032782 bile acid secretion(GO:0032782)
0.1 4.3 GO:0006513 protein monoubiquitination(GO:0006513)
0.1 0.2 GO:0046077 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.1 0.5 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.5 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 1.2 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.6 GO:0006465 signal peptide processing(GO:0006465)
0.0 1.3 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.5 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0 0.6 GO:0017144 drug metabolic process(GO:0017144)
0.0 1.5 GO:0019915 lipid storage(GO:0019915)
0.0 0.8 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 1.1 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 1.1 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 0.7 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.6 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.2 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.9 GO:0016180 snRNA processing(GO:0016180)
0.0 1.9 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 1.6 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 1.1 GO:0043029 T cell homeostasis(GO:0043029)
0.0 0.6 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.2 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.0 0.4 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.2 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.4 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 1.1 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.3 GO:0046486 glycerolipid metabolic process(GO:0046486)
0.0 0.1 GO:2000018 regulation of male gonad development(GO:2000018) positive regulation of male gonad development(GO:2000020)
0.0 0.4 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.1 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.0 0.1 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098) response to amino acid starvation(GO:1990928)
0.0 3.7 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 0.4 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 1.6 GO:0048636 positive regulation of striated muscle tissue development(GO:0045844) positive regulation of muscle organ development(GO:0048636) positive regulation of muscle tissue development(GO:1901863)
0.0 0.5 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.6 GO:0032259 methylation(GO:0032259)
0.0 0.4 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0097501 stress response to metal ion(GO:0097501)
0.0 0.1 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 1.0 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.6 GO:1901796 regulation of signal transduction by p53 class mediator(GO:1901796)
0.0 4.1 GO:0010001 glial cell differentiation(GO:0010001)
0.0 0.4 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.0 2.1 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.4 GO:0033622 integrin activation(GO:0033622)
0.0 0.2 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 1.5 GO:0051099 positive regulation of binding(GO:0051099)
0.0 0.4 GO:0006414 translational elongation(GO:0006414)
0.0 0.7 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.1 GO:0044065 regulation of respiratory system process(GO:0044065)
0.0 1.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.6 GO:0017145 stem cell division(GO:0017145)
0.0 0.3 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 0.3 GO:0045103 intermediate filament-based process(GO:0045103)
0.0 0.8 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.8 GO:0007601 visual perception(GO:0007601)
0.0 0.2 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 8.9 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
1.5 10.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
1.2 3.7 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
1.0 3.0 GO:0042585 germinal vesicle(GO:0042585)
0.9 4.7 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.9 7.3 GO:0005818 aster(GO:0005818)
0.8 5.0 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.8 4.0 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.6 1.9 GO:0099573 glutamatergic postsynaptic density(GO:0099573)
0.6 3.2 GO:0030314 junctional membrane complex(GO:0030314)
0.6 8.6 GO:0030061 mitochondrial crista(GO:0030061)
0.5 2.6 GO:0031523 Myb complex(GO:0031523)
0.5 2.0 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.5 1.5 GO:0005588 collagen type V trimer(GO:0005588)
0.5 1.0 GO:0099524 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.5 5.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.5 1.8 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.4 1.3 GO:0030905 retromer, tubulation complex(GO:0030905)
0.4 2.5 GO:0097512 cardiac myofibril(GO:0097512)
0.3 1.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.3 2.4 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.3 1.0 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.3 6.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.3 17.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.3 3.0 GO:0031080 nuclear pore outer ring(GO:0031080)
0.3 2.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.3 2.3 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.2 1.6 GO:0097524 sperm plasma membrane(GO:0097524)
0.2 2.3 GO:0031595 nuclear proteasome complex(GO:0031595)
0.2 3.4 GO:0045180 basal cortex(GO:0045180)
0.2 2.7 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.2 3.2 GO:0097539 ciliary transition fiber(GO:0097539)
0.2 2.1 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.2 0.8 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.2 1.6 GO:0000243 commitment complex(GO:0000243)
0.2 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 12.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.2 1.4 GO:0031091 platelet alpha granule(GO:0031091)
0.2 1.9 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.2 1.4 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 2.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 2.0 GO:0042101 T cell receptor complex(GO:0042101)
0.1 4.1 GO:0051233 spindle midzone(GO:0051233)
0.1 1.0 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 6.8 GO:0016459 myosin complex(GO:0016459)
0.1 1.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 1.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 0.7 GO:0098536 deuterosome(GO:0098536)
0.1 10.7 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.1 0.2 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 5.9 GO:0005882 intermediate filament(GO:0005882)
0.1 6.5 GO:0031985 Golgi cisterna(GO:0031985)
0.1 2.1 GO:0045171 intercellular bridge(GO:0045171)
0.1 0.5 GO:0032389 MutLalpha complex(GO:0032389)
0.1 0.7 GO:0005787 signal peptidase complex(GO:0005787)
0.1 1.3 GO:0005614 interstitial matrix(GO:0005614)
0.1 4.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 2.7 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.4 GO:0031501 mannosyltransferase complex(GO:0031501)
0.1 5.6 GO:0030315 T-tubule(GO:0030315)
0.1 1.0 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.1 0.5 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 0.5 GO:0071203 WASH complex(GO:0071203)
0.1 0.6 GO:0060091 kinocilium(GO:0060091)
0.1 1.0 GO:0031011 Ino80 complex(GO:0031011)
0.1 0.8 GO:0000974 Prp19 complex(GO:0000974)
0.1 0.9 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 1.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.8 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 0.9 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 5.5 GO:0005604 basement membrane(GO:0005604)
0.1 1.6 GO:0031526 brush border membrane(GO:0031526)
0.1 2.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.7 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 4.1 GO:0005811 lipid particle(GO:0005811)
0.1 1.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 0.9 GO:0036038 MKS complex(GO:0036038)
0.1 3.2 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 3.5 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 0.9 GO:0032039 integrator complex(GO:0032039)
0.1 5.6 GO:0000790 nuclear chromatin(GO:0000790)
0.1 1.3 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 2.5 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.7 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 1.1 GO:0001741 XY body(GO:0001741)
0.0 5.1 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 0.4 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 5.1 GO:0005681 spliceosomal complex(GO:0005681)
0.0 1.2 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 1.5 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.9 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 5.3 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 1.5 GO:0005871 kinesin complex(GO:0005871)
0.0 0.6 GO:0001891 phagocytic cup(GO:0001891)
0.0 9.4 GO:0009986 cell surface(GO:0009986)
0.0 4.6 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 4.0 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.2 GO:0097422 tubular endosome(GO:0097422)
0.0 1.0 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0030663 COPI vesicle coat(GO:0030126) COPI-coated vesicle membrane(GO:0030663)
0.0 2.8 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 5.8 GO:0016607 nuclear speck(GO:0016607)
0.0 0.2 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.9 GO:0032432 actin filament bundle(GO:0032432)
0.0 2.5 GO:0031965 nuclear membrane(GO:0031965)
0.0 1.1 GO:0000502 proteasome complex(GO:0000502)
0.0 0.2 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 0.5 GO:0030175 filopodium(GO:0030175)
0.0 0.2 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 10.3 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
2.2 4.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
1.7 5.0 GO:0004774 succinate-CoA ligase activity(GO:0004774)
1.5 5.9 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
1.1 8.9 GO:0031995 insulin-like growth factor II binding(GO:0031995)
1.1 4.4 GO:0045131 pre-mRNA branch point binding(GO:0045131)
1.0 3.0 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
1.0 3.9 GO:2001069 glycogen binding(GO:2001069)
1.0 21.2 GO:0070410 co-SMAD binding(GO:0070410)
0.9 4.6 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.8 2.5 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.8 3.3 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.8 7.3 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.8 5.6 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.8 3.9 GO:0005534 galactose binding(GO:0005534)
0.7 4.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.7 5.8 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.7 9.1 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.7 12.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.6 2.6 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.6 2.6 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.6 3.7 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.6 3.0 GO:0035174 histone serine kinase activity(GO:0035174)
0.6 2.3 GO:0042806 fucose binding(GO:0042806)
0.5 1.6 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.5 7.3 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.5 3.0 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.5 3.4 GO:0043559 insulin binding(GO:0043559)
0.5 1.8 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.5 2.7 GO:0070644 vitamin D response element binding(GO:0070644)
0.4 1.3 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.4 2.7 GO:0016018 cyclosporin A binding(GO:0016018)
0.4 3.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.4 2.0 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.4 0.4 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.4 1.2 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.4 3.8 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.4 4.6 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.4 1.8 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.4 2.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.3 1.3 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.3 2.3 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.3 1.3 GO:1990460 leptin receptor binding(GO:1990460)
0.3 1.0 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.3 2.1 GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.3 2.0 GO:1901612 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.3 5.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.3 1.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.3 2.8 GO:0042301 phosphate ion binding(GO:0042301)
0.3 1.6 GO:0002135 CTP binding(GO:0002135)
0.3 4.8 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.3 2.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.3 3.1 GO:0070097 delta-catenin binding(GO:0070097)
0.3 1.8 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.3 4.1 GO:0030957 Tat protein binding(GO:0030957)
0.2 1.7 GO:0032554 purine deoxyribonucleotide binding(GO:0032554)
0.2 8.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.2 11.3 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.2 0.6 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.2 2.3 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.2 1.2 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.2 1.0 GO:0043532 angiostatin binding(GO:0043532)
0.2 2.6 GO:0019215 intermediate filament binding(GO:0019215)
0.2 1.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 0.6 GO:0030284 estrogen receptor activity(GO:0030284)
0.2 1.4 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.2 0.5 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.2 6.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.2 6.8 GO:0005158 insulin receptor binding(GO:0005158)
0.2 2.4 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.2 0.5 GO:0032052 bile acid binding(GO:0032052)
0.2 2.8 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.2 0.7 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.2 1.9 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.2 1.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 1.1 GO:0043237 laminin-1 binding(GO:0043237)
0.2 1.0 GO:0042731 PH domain binding(GO:0042731)
0.2 2.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 1.1 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.1 3.9 GO:0071837 HMG box domain binding(GO:0071837)
0.1 4.3 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 0.9 GO:0034452 dynactin binding(GO:0034452)
0.1 0.8 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.1 0.5 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.1 4.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 1.8 GO:0016805 dipeptidase activity(GO:0016805)
0.1 0.5 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.1 2.5 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 0.6 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1 1.2 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 4.6 GO:0070888 E-box binding(GO:0070888)
0.1 0.6 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.1 2.4 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.1 0.7 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.7 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 1.7 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.1 0.6 GO:0019770 IgG receptor activity(GO:0019770)
0.1 3.0 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 3.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 32.9 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 0.5 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 7.6 GO:0019955 cytokine binding(GO:0019955)
0.1 3.2 GO:0005109 frizzled binding(GO:0005109)
0.1 4.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.9 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.1 0.7 GO:0046790 virion binding(GO:0046790)
0.1 0.7 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 0.4 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.1 0.4 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 0.7 GO:0001972 retinoic acid binding(GO:0001972)
0.1 3.1 GO:0005112 Notch binding(GO:0005112)
0.1 1.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 0.9 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.2 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.1 1.8 GO:0051018 protein kinase A binding(GO:0051018)
0.1 11.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 0.7 GO:0008430 selenium binding(GO:0008430)
0.1 1.1 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.1 1.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 1.2 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 1.3 GO:0001968 fibronectin binding(GO:0001968)
0.1 5.1 GO:0005125 cytokine activity(GO:0005125)
0.1 0.2 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.1 3.4 GO:0008083 growth factor activity(GO:0008083)
0.1 0.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 0.2 GO:0052740 phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 0.5 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 1.1 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 4.7 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987)
0.0 1.6 GO:0017069 snRNA binding(GO:0017069)
0.0 4.4 GO:0003774 motor activity(GO:0003774)
0.0 0.5 GO:0000182 rDNA binding(GO:0000182)
0.0 0.2 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.4 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 6.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 5.1 GO:0008237 metallopeptidase activity(GO:0008237)
0.0 1.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 1.8 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 0.9 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 0.1 GO:0016493 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950) C-C chemokine receptor activity(GO:0016493)
0.0 0.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 1.0 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.4 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.7 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.2 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 1.9 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 2.7 GO:0051015 actin filament binding(GO:0051015)
0.0 0.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.6 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.4 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 1.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.8 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.2 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.2 GO:0022842 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.0 0.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.2 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 3.3 GO:0045296 cadherin binding(GO:0045296)
0.0 0.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.5 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.5 GO:0005178 integrin binding(GO:0005178)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 35.9 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.3 10.4 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.3 11.2 PID_AURORA_A_PATHWAY Aurora A signaling
0.3 14.8 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.3 5.2 PID_BARD1_PATHWAY BARD1 signaling events
0.2 4.3 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.2 7.6 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.2 9.1 PID_BMP_PATHWAY BMP receptor signaling
0.2 7.7 PID_ATM_PATHWAY ATM pathway
0.2 8.7 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.2 5.2 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.2 5.2 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.2 4.7 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.2 3.3 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.1 4.6 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 4.5 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.1 6.4 PID_PLK1_PATHWAY PLK1 signaling events
0.1 2.7 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.1 4.6 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 13.1 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 6.3 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.1 1.8 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.1 8.9 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.1 12.4 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.4 PID_RAS_PATHWAY Regulation of Ras family activation
0.1 2.3 NABA_COLLAGENS Genes encoding collagen proteins
0.1 5.4 PID_CDC42_PATHWAY CDC42 signaling events
0.1 1.5 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.1 2.9 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.1 2.1 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 2.6 PID_AP1_PATHWAY AP-1 transcription factor network
0.1 1.2 PID_IFNG_PATHWAY IFN-gamma pathway
0.0 2.0 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.8 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.0 0.5 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 1.5 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 1.0 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.2 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.0 1.1 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 1.1 PID_ERBB1_DOWNSTREAM_PATHWAY ErbB1 downstream signaling
0.0 0.1 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.0 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.3 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.6 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.4 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 0.3 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 0.4 ST_FAS_SIGNALING_PATHWAY Fas Signaling Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.7 REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.6 5.6 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.6 21.2 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.6 8.9 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.5 4.6 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.4 4.9 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.4 9.0 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.4 11.8 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.3 2.4 REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.3 7.1 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.3 10.3 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.3 11.3 REACTOME_G1_PHASE Genes involved in G1 Phase
0.2 5.2 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.2 5.0 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.2 1.8 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.2 2.5 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.2 9.0 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.2 12.3 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.2 5.5 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.2 9.8 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.2 3.0 REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1 3.4 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 4.9 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 0.6 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 2.8 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 0.7 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 5.7 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 5.2 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.1 3.2 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.1 1.5 REACTOME_PECAM1_INTERACTIONS Genes involved in PECAM1 interactions
0.1 5.2 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 2.8 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 5.4 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 1.9 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 2.2 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.1 0.7 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 0.2 REACTOME_ADP_SIGNALLING_THROUGH_P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.1 1.8 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 3.1 REACTOME_INTERFERON_GAMMA_SIGNALING Genes involved in Interferon gamma signaling
0.1 1.2 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 1.6 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.1 0.9 REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.1 2.3 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 0.5 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.0 0.6 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.6 REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS Genes involved in G alpha (z) signalling events
0.0 0.3 REACTOME_P53_DEPENDENT_G1_DNA_DAMAGE_RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.0 0.6 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 1.6 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.6 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.0 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.9 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.9 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 2.1 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.7 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.3 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 2.0 REACTOME_TRANSPORT_OF_GLUCOSE_AND_OTHER_SUGARS_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS Genes involved in Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
0.0 2.5 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.9 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 3.2 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.0 0.4 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 3.9 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.9 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 2.0 REACTOME_SIGNALING_BY_PDGF Genes involved in Signaling by PDGF
0.0 0.8 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.8 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 1.5 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.4 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.9 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 2.3 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.1 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.8 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation