Motif ID: Gbx1_Nobox_Alx3

Z-value: 0.608

Transcription factors associated with Gbx1_Nobox_Alx3:

Gene SymbolEntrez IDGene Name
Alx3 ENSMUSG00000014603.1 Alx3
Gbx1 ENSMUSG00000067724.4 Gbx1
Nobox ENSMUSG00000029736.9 Nobox

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Alx3mm10_v2_chr3_+_107595031_107595164-0.211.8e-01Click!
Gbx1mm10_v2_chr5_-_24527276_245272760.114.9e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Gbx1_Nobox_Alx3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_139543889 5.587 ENSMUST00000174792.1
ENSMUST00000031523.8
Uncx

UNC homeobox

chr11_-_98053415 4.870 ENSMUST00000017544.2
Stac2
SH3 and cysteine rich domain 2
chrX_-_143933089 3.875 ENSMUST00000087313.3
Dcx
doublecortin
chr1_-_158356258 3.330 ENSMUST00000004133.8
Brinp2
bone morphogenic protein/retinoic acid inducible neural-specific 2
chr12_+_52699297 3.107 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chr12_+_38780817 2.979 ENSMUST00000160856.1
Etv1
ets variant gene 1
chr12_+_38780284 2.873 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
Etv1


ets variant gene 1


chr3_+_55782500 2.751 ENSMUST00000075422.4
Mab21l1
mab-21-like 1 (C. elegans)
chr7_+_126950518 2.651 ENSMUST00000106335.1
ENSMUST00000146017.1
Sez6l2

seizure related 6 homolog like 2

chr10_+_127421208 2.402 ENSMUST00000168780.1
R3hdm2
R3H domain containing 2
chr18_+_23415400 2.391 ENSMUST00000115832.2
ENSMUST00000047954.7
Dtna

dystrobrevin alpha

chr1_-_155417394 2.366 ENSMUST00000111775.1
ENSMUST00000111774.1
Xpr1

xenotropic and polytropic retrovirus receptor 1

chr7_+_126950687 2.292 ENSMUST00000106333.1
Sez6l2
seizure related 6 homolog like 2
chr5_-_62766153 2.259 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr1_+_72284367 2.184 ENSMUST00000027380.5
ENSMUST00000141783.1
Tmem169

transmembrane protein 169

chr16_-_37384915 2.180 ENSMUST00000114787.1
ENSMUST00000114782.1
ENSMUST00000023526.2
ENSMUST00000114775.1
Stxbp5l



syntaxin binding protein 5-like



chr12_+_109545390 2.153 ENSMUST00000146701.1
Meg3
maternally expressed 3
chr8_+_23669653 2.111 ENSMUST00000042352.4
Zmat4
zinc finger, matrin type 4
chr12_-_83487708 2.042 ENSMUST00000177959.1
ENSMUST00000178756.1
Dpf3

D4, zinc and double PHD fingers, family 3

chr15_+_18818895 2.021 ENSMUST00000166873.2
Cdh10
cadherin 10
chrX_-_143933204 1.974 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chr13_+_44121167 1.946 ENSMUST00000163056.1
ENSMUST00000159595.1
Gm5083

predicted gene 5083

chr4_+_108719649 1.935 ENSMUST00000178992.1
3110021N24Rik
RIKEN cDNA 3110021N24 gene
chr10_+_73821857 1.906 ENSMUST00000177128.1
ENSMUST00000064562.7
ENSMUST00000129404.2
ENSMUST00000105426.3
ENSMUST00000131321.2
ENSMUST00000126920.2
ENSMUST00000147189.2
ENSMUST00000105424.3
ENSMUST00000092420.6
ENSMUST00000105429.3
ENSMUST00000131724.2
ENSMUST00000152655.2
ENSMUST00000151116.2
ENSMUST00000155701.2
ENSMUST00000152819.2
ENSMUST00000125517.2
ENSMUST00000124046.1
ENSMUST00000149977.2
ENSMUST00000146682.1
ENSMUST00000177107.1
Pcdh15



















protocadherin 15



















chr5_-_66514815 1.856 ENSMUST00000161879.1
ENSMUST00000159357.1
Apbb2

amyloid beta (A4) precursor protein-binding, family B, member 2

chr2_+_125136692 1.830 ENSMUST00000099452.2
Ctxn2
cortexin 2
chr12_+_72441852 1.766 ENSMUST00000162159.1
Lrrc9
leucine rich repeat containing 9
chr9_+_32116040 1.756 ENSMUST00000174641.1
Arhgap32
Rho GTPase activating protein 32
chr18_-_75697639 1.753 ENSMUST00000165559.1
Ctif
CBP80/20-dependent translation initiation factor
chr9_-_55919605 1.750 ENSMUST00000037408.8
Scaper
S phase cyclin A-associated protein in the ER
chr12_+_38781093 1.736 ENSMUST00000161513.1
Etv1
ets variant gene 1
chr3_+_55461758 1.718 ENSMUST00000070418.4
Dclk1
doublecortin-like kinase 1
chr6_+_29853746 1.653 ENSMUST00000064872.6
ENSMUST00000152581.1
ENSMUST00000176265.1
ENSMUST00000154079.1
Ahcyl2



S-adenosylhomocysteine hydrolase-like 2



chr1_-_190170671 1.564 ENSMUST00000175916.1
Prox1
prospero-related homeobox 1
chr9_+_113812547 1.511 ENSMUST00000166734.2
ENSMUST00000111838.2
ENSMUST00000163895.2
Clasp2


CLIP associating protein 2


chr2_+_109917639 1.492 ENSMUST00000046548.7
ENSMUST00000111037.2
Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chr4_-_129261394 1.480 ENSMUST00000145261.1
C77080
expressed sequence C77080
chr16_-_37384940 1.437 ENSMUST00000114781.1
ENSMUST00000114780.1
Stxbp5l

syntaxin binding protein 5-like

chr12_-_91849081 1.423 ENSMUST00000167466.1
ENSMUST00000021347.5
ENSMUST00000178462.1
Sel1l


sel-1 suppressor of lin-12-like (C. elegans)


chr13_+_94083490 1.386 ENSMUST00000156071.1
Lhfpl2
lipoma HMGIC fusion partner-like 2
chr16_-_45724600 1.367 ENSMUST00000096057.4
Tagln3
transgelin 3
chr12_+_55598917 1.343 ENSMUST00000051857.3
Insm2
insulinoma-associated 2
chr1_+_109983737 1.321 ENSMUST00000172005.1
Cdh7
cadherin 7, type 2
chr4_-_155056784 1.318 ENSMUST00000131173.2
Plch2
phospholipase C, eta 2
chr1_-_134955847 1.302 ENSMUST00000168381.1
Ppp1r12b
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr5_+_121777929 1.299 ENSMUST00000160821.1
Atxn2
ataxin 2
chr2_-_144527341 1.278 ENSMUST00000163701.1
ENSMUST00000081982.5
Dzank1

double zinc ribbon and ankyrin repeat domains 1

chrM_+_7759 1.260 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr10_+_127420867 1.224 ENSMUST00000064793.6
R3hdm2
R3H domain containing 2
chr1_-_79440039 1.215 ENSMUST00000049972.4
Scg2
secretogranin II
chr18_+_23752333 1.211 ENSMUST00000170802.1
ENSMUST00000155708.1
ENSMUST00000118826.2
Mapre2


microtubule-associated protein, RP/EB family, member 2


chr2_+_69897255 1.207 ENSMUST00000131553.1
Ubr3
ubiquitin protein ligase E3 component n-recognin 3
chr6_+_37870786 1.200 ENSMUST00000120428.1
ENSMUST00000031859.7
Trim24

tripartite motif-containing 24

chr10_+_127421124 1.144 ENSMUST00000170336.1
R3hdm2
R3H domain containing 2
chr9_-_103222063 1.137 ENSMUST00000170904.1
Trf
transferrin
chrM_+_9870 1.136 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr13_+_42680565 1.036 ENSMUST00000128646.1
Phactr1
phosphatase and actin regulator 1
chr14_-_100149764 1.023 ENSMUST00000097079.4
Klf12
Kruppel-like factor 12
chr3_+_5218516 1.023 ENSMUST00000175866.1
Zfhx4
zinc finger homeodomain 4
chr14_-_37098211 1.021 ENSMUST00000022337.9
Cdhr1
cadherin-related family member 1
chr15_+_92597104 0.996 ENSMUST00000035399.8
Pdzrn4
PDZ domain containing RING finger 4
chr16_-_63864114 0.980 ENSMUST00000064405.6
Epha3
Eph receptor A3
chr6_-_23248264 0.980 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr19_-_14597983 0.975 ENSMUST00000052011.7
Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr16_-_74411292 0.961 ENSMUST00000117200.1
Robo2
roundabout homolog 2 (Drosophila)
chr10_-_117148474 0.953 ENSMUST00000020381.3
Frs2
fibroblast growth factor receptor substrate 2
chr15_-_11037968 0.940 ENSMUST00000058007.5
Rxfp3
relaxin family peptide receptor 3
chr2_-_45112890 0.920 ENSMUST00000076836.6
Zeb2
zinc finger E-box binding homeobox 2
chr7_+_123123870 0.918 ENSMUST00000094053.5
Tnrc6a
trinucleotide repeat containing 6a
chr1_-_172027251 0.915 ENSMUST00000138714.1
Vangl2
vang-like 2 (van gogh, Drosophila)
chr1_-_134955908 0.909 ENSMUST00000045665.6
ENSMUST00000086444.4
ENSMUST00000112163.1
Ppp1r12b


protein phosphatase 1, regulatory (inhibitor) subunit 12B


chr10_-_25200110 0.902 ENSMUST00000100012.2
Akap7
A kinase (PRKA) anchor protein 7
chr10_+_39612934 0.902 ENSMUST00000019987.6
Traf3ip2
TRAF3 interacting protein 2
chr4_+_150853919 0.873 ENSMUST00000073600.2
Errfi1
ERBB receptor feedback inhibitor 1
chr19_-_14598031 0.867 ENSMUST00000167776.2
Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr8_+_4238815 0.861 ENSMUST00000003027.7
ENSMUST00000110999.1
Map2k7

mitogen-activated protein kinase kinase 7

chr11_-_107337556 0.851 ENSMUST00000040380.6
Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chr3_+_125404072 0.850 ENSMUST00000173932.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr7_+_35802593 0.825 ENSMUST00000052454.2
E130304I02Rik
RIKEN cDNA E130304I02 gene
chr10_+_127420334 0.815 ENSMUST00000171434.1
R3hdm2
R3H domain containing 2
chr12_+_38783455 0.809 ENSMUST00000161980.1
ENSMUST00000160701.1
Etv1

ets variant gene 1

chr6_+_125552948 0.808 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Vwf


Von Willebrand factor homolog


chr11_-_87359011 0.805 ENSMUST00000055438.4
Ppm1e
protein phosphatase 1E (PP2C domain containing)
chr14_-_36919314 0.790 ENSMUST00000182797.1
Ccser2
coiled-coil serine rich 2
chr6_+_15196949 0.790 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
Foxp2



forkhead box P2



chr8_+_45658666 0.790 ENSMUST00000134675.1
ENSMUST00000139869.1
ENSMUST00000126067.1
Sorbs2


sorbin and SH3 domain containing 2


chr3_-_127225847 0.789 ENSMUST00000182726.1
ENSMUST00000182779.1
Ank2

ankyrin 2, brain

chr5_+_81021202 0.786 ENSMUST00000117253.1
ENSMUST00000120128.1
Lphn3

latrophilin 3

chr2_+_121956651 0.785 ENSMUST00000110574.1
Ctdspl2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr3_+_109573907 0.781 ENSMUST00000106576.2
Vav3
vav 3 oncogene
chr2_-_37359274 0.774 ENSMUST00000009174.8
Pdcl
phosducin-like
chr8_+_45658731 0.767 ENSMUST00000143820.1
ENSMUST00000132139.1
Sorbs2

sorbin and SH3 domain containing 2

chr1_-_22315792 0.767 ENSMUST00000164877.1
Rims1
regulating synaptic membrane exocytosis 1
chr3_-_127225917 0.765 ENSMUST00000182064.1
ENSMUST00000182662.1
Ank2

ankyrin 2, brain

chr8_+_121116163 0.760 ENSMUST00000054691.6
Foxc2
forkhead box C2
chr14_-_88471396 0.760 ENSMUST00000061628.5
Pcdh20
protocadherin 20
chr3_+_86070915 0.745 ENSMUST00000182666.1
Sh3d19
SH3 domain protein D19
chr1_-_190170178 0.721 ENSMUST00000177288.1
Prox1
prospero-related homeobox 1
chr9_-_16378231 0.717 ENSMUST00000082170.5
Fat3
FAT tumor suppressor homolog 3 (Drosophila)
chr16_+_33684538 0.704 ENSMUST00000126532.1
Heg1
HEG homolog 1 (zebrafish)
chr18_-_24603464 0.704 ENSMUST00000154205.1
Slc39a6
solute carrier family 39 (metal ion transporter), member 6
chr12_+_38783503 0.703 ENSMUST00000159334.1
Etv1
ets variant gene 1
chr1_+_132298606 0.692 ENSMUST00000046071.4
Klhdc8a
kelch domain containing 8A
chr8_-_36249292 0.687 ENSMUST00000065297.5
Lonrf1
LON peptidase N-terminal domain and ring finger 1
chr12_+_72441933 0.685 ENSMUST00000161284.1
Lrrc9
leucine rich repeat containing 9
chr9_+_118478182 0.679 ENSMUST00000111763.1
Eomes
eomesodermin homolog (Xenopus laevis)
chr5_+_19907774 0.671 ENSMUST00000115267.2
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr18_+_37518341 0.666 ENSMUST00000097609.1
Pcdhb22
protocadherin beta 22
chr10_-_6980376 0.660 ENSMUST00000105617.1
Ipcef1
interaction protein for cytohesin exchange factors 1
chr2_+_69897220 0.653 ENSMUST00000055758.9
ENSMUST00000112251.2
Ubr3

ubiquitin protein ligase E3 component n-recognin 3

chrM_+_10167 0.651 ENSMUST00000082414.1
mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr3_+_5218546 0.649 ENSMUST00000026284.6
Zfhx4
zinc finger homeodomain 4
chr2_-_79456750 0.641 ENSMUST00000041099.4
Neurod1
neurogenic differentiation 1
chr6_-_147264124 0.623 ENSMUST00000052296.6
Pthlh
parathyroid hormone-like peptide
chr5_+_88583527 0.623 ENSMUST00000031229.6
Rufy3
RUN and FYVE domain containing 3
chr7_+_64502090 0.618 ENSMUST00000137732.1
Apba2
amyloid beta (A4) precursor protein-binding, family A, member 2
chr6_+_7555053 0.611 ENSMUST00000090679.2
ENSMUST00000184986.1
Tac1

tachykinin 1

chr1_-_24612700 0.587 ENSMUST00000088336.1
Gm10222
predicted gene 10222
chr15_+_21111452 0.586 ENSMUST00000075132.6
Cdh12
cadherin 12
chr15_+_81936911 0.580 ENSMUST00000135663.1
Csdc2
cold shock domain containing C2, RNA binding
chr11_-_102897123 0.574 ENSMUST00000067444.3
Gfap
glial fibrillary acidic protein
chr5_+_81021583 0.572 ENSMUST00000121707.1
Lphn3
latrophilin 3
chr2_-_77519565 0.572 ENSMUST00000111830.2
Zfp385b
zinc finger protein 385B
chr8_+_45627709 0.563 ENSMUST00000134321.1
ENSMUST00000135336.1
Sorbs2

sorbin and SH3 domain containing 2

chr13_+_44729535 0.559 ENSMUST00000174068.1
Jarid2
jumonji, AT rich interactive domain 2
chr5_-_137684665 0.552 ENSMUST00000100544.4
ENSMUST00000031736.9
ENSMUST00000151839.1
Agfg2


ArfGAP with FG repeats 2


chr9_+_54980880 0.550 ENSMUST00000093844.3
Chrna5
cholinergic receptor, nicotinic, alpha polypeptide 5
chr1_+_110099295 0.550 ENSMUST00000134301.1
Cdh7
cadherin 7, type 2
chr9_+_45370185 0.549 ENSMUST00000085939.6
Fxyd6
FXYD domain-containing ion transport regulator 6
chr2_+_121956411 0.543 ENSMUST00000110578.1
Ctdspl2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr17_-_29888570 0.542 ENSMUST00000171691.1
Mdga1
MAM domain containing glycosylphosphatidylinositol anchor 1
chr2_-_18048784 0.541 ENSMUST00000142856.1
Skida1
SKI/DACH domain containing 1
chr9_-_15357692 0.540 ENSMUST00000098979.3
ENSMUST00000161132.1
5830418K08Rik

RIKEN cDNA 5830418K08 gene

chr6_-_122340499 0.532 ENSMUST00000160843.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr11_+_23306910 0.530 ENSMUST00000137823.1
Usp34
ubiquitin specific peptidase 34
chr15_-_33687840 0.528 ENSMUST00000042021.3
Tspyl5
testis-specific protein, Y-encoded-like 5
chr1_+_180109192 0.528 ENSMUST00000143176.1
ENSMUST00000135056.1
Cdc42bpa

CDC42 binding protein kinase alpha

chr5_-_72587544 0.527 ENSMUST00000031124.4
Gm5868
predicted gene 5868
chr6_-_57535422 0.519 ENSMUST00000042766.3
Ppm1k
protein phosphatase 1K (PP2C domain containing)
chr3_+_5218589 0.512 ENSMUST00000177488.1
Zfhx4
zinc finger homeodomain 4
chr17_-_35697971 0.510 ENSMUST00000146472.1
Ddr1
discoidin domain receptor family, member 1
chr3_-_17786834 0.497 ENSMUST00000099198.2
Gm10742
predicted gene 10742
chr16_-_42340595 0.496 ENSMUST00000102817.4
Gap43
growth associated protein 43
chr19_+_26750939 0.491 ENSMUST00000175953.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr16_+_42907563 0.490 ENSMUST00000151244.1
ENSMUST00000114694.2
Zbtb20

zinc finger and BTB domain containing 20

chr3_-_88425094 0.486 ENSMUST00000168755.1
ENSMUST00000057935.6
Slc25a44

solute carrier family 25, member 44

chr18_-_61707583 0.483 ENSMUST00000025472.1
Pcyox1l
prenylcysteine oxidase 1 like
chrX_+_151803313 0.478 ENSMUST00000026292.8
Huwe1
HECT, UBA and WWE domain containing 1
chr7_+_126950837 0.476 ENSMUST00000106332.1
Sez6l2
seizure related 6 homolog like 2
chr1_-_132390301 0.472 ENSMUST00000132435.1
Tmcc2
transmembrane and coiled-coil domains 2
chr15_-_81360739 0.467 ENSMUST00000023040.7
Slc25a17
solute carrier family 25 (mitochondrial carrier, peroxisomal membrane protein), member 17
chr14_-_108914237 0.461 ENSMUST00000100322.2
Slitrk1
SLIT and NTRK-like family, member 1
chr2_+_155382186 0.460 ENSMUST00000134218.1
Trp53inp2
transformation related protein 53 inducible nuclear protein 2
chr2_+_144527718 0.458 ENSMUST00000028914.2
ENSMUST00000110017.2
Polr3f

polymerase (RNA) III (DNA directed) polypeptide F

chr5_+_29195983 0.456 ENSMUST00000160888.1
ENSMUST00000159272.1
ENSMUST00000001247.5
ENSMUST00000161398.1
ENSMUST00000160246.1
Rnf32




ring finger protein 32




chr19_-_46969474 0.454 ENSMUST00000086961.7
Nt5c2
5'-nucleotidase, cytosolic II
chrX_+_23693043 0.434 ENSMUST00000035766.6
ENSMUST00000101670.2
Wdr44

WD repeat domain 44

chr6_+_29859662 0.434 ENSMUST00000128927.2
Ahcyl2
S-adenosylhomocysteine hydrolase-like 2
chr16_-_97170707 0.429 ENSMUST00000056102.7
Dscam
Down syndrome cell adhesion molecule
chr2_+_65930117 0.425 ENSMUST00000176109.1
Csrnp3
cysteine-serine-rich nuclear protein 3
chr7_+_64501949 0.424 ENSMUST00000138829.1
Apba2
amyloid beta (A4) precursor protein-binding, family A, member 2
chr3_+_125404292 0.420 ENSMUST00000144344.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr6_+_29859686 0.418 ENSMUST00000134438.1
Ahcyl2
S-adenosylhomocysteine hydrolase-like 2
chr11_-_20332654 0.415 ENSMUST00000004634.6
Slc1a4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr11_+_103133333 0.412 ENSMUST00000124928.1
ENSMUST00000062530.4
Hexim2

hexamethylene bis-acetamide inducible 2

chr6_-_148831395 0.410 ENSMUST00000145960.1
Ipo8
importin 8
chr8_+_107031218 0.407 ENSMUST00000034388.9
Vps4a
vacuolar protein sorting 4a (yeast)
chr3_-_19264959 0.406 ENSMUST00000121951.1
Pde7a
phosphodiesterase 7A
chr18_-_84086379 0.404 ENSMUST00000060303.8
Tshz1
teashirt zinc finger family member 1
chr3_+_62419668 0.404 ENSMUST00000161057.1
Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr17_-_90088343 0.403 ENSMUST00000173917.1
Nrxn1
neurexin I
chr19_-_29334646 0.403 ENSMUST00000044143.5
Rln1
relaxin 1
chr5_+_144100387 0.399 ENSMUST00000041804.7
Lmtk2
lemur tyrosine kinase 2
chr3_+_94837702 0.399 ENSMUST00000107266.1
ENSMUST00000042402.5
ENSMUST00000107269.1
Pogz


pogo transposable element with ZNF domain


chr7_-_45103747 0.396 ENSMUST00000003512.7
Fcgrt
Fc receptor, IgG, alpha chain transporter
chr13_-_102906046 0.396 ENSMUST00000171791.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr4_+_144893127 0.395 ENSMUST00000142808.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr16_+_52031549 0.389 ENSMUST00000114471.1
Cblb
Casitas B-lineage lymphoma b
chrX_+_159708593 0.387 ENSMUST00000080394.6
Sh3kbp1
SH3-domain kinase binding protein 1
chr9_-_105521147 0.386 ENSMUST00000176770.1
ENSMUST00000085133.6
Atp2c1

ATPase, Ca++-sequestering

chr6_-_101377897 0.378 ENSMUST00000075994.6
Pdzrn3
PDZ domain containing RING finger 3
chr7_-_99141068 0.375 ENSMUST00000037968.8
Uvrag
UV radiation resistance associated gene
chr4_+_8690399 0.374 ENSMUST00000127476.1
Chd7
chromodomain helicase DNA binding protein 7
chr11_-_20332689 0.372 ENSMUST00000109594.1
Slc1a4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr18_-_24603791 0.371 ENSMUST00000070726.3
Slc39a6
solute carrier family 39 (metal ion transporter), member 6
chr1_-_155417283 0.371 ENSMUST00000027741.5
Xpr1
xenotropic and polytropic retrovirus receptor 1
chr19_+_11965817 0.368 ENSMUST00000025590.9
Osbp
oxysterol binding protein
chr9_-_96631487 0.366 ENSMUST00000128346.1
ENSMUST00000034984.6
Rasa2

RAS p21 protein activator 2

chr3_+_89520152 0.364 ENSMUST00000000811.7
Kcnn3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr6_-_136171722 0.360 ENSMUST00000053880.6
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr3_+_94837533 0.360 ENSMUST00000107270.2
Pogz
pogo transposable element with ZNF domain
chr1_-_121332571 0.359 ENSMUST00000071064.6
Insig2
insulin induced gene 2
chr2_-_62483637 0.358 ENSMUST00000136686.1
ENSMUST00000102733.3
Gcg

glucagon

chr4_+_65604984 0.357 ENSMUST00000050850.7
ENSMUST00000107366.1
Trim32

tripartite motif-containing 32

chr2_+_23069210 0.354 ENSMUST00000155602.1
Acbd5
acyl-Coenzyme A binding domain containing 5
chr10_+_62980233 0.346 ENSMUST00000131718.1
ENSMUST00000119567.1
ENSMUST00000122231.1
Rufy2


RUN and FYVE domain-containing 2


chr5_+_14025305 0.344 ENSMUST00000073957.6
Sema3e
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chrX_-_95658379 0.343 ENSMUST00000119640.1
Zc4h2
zinc finger, C4H2 domain containing
chr7_+_79273201 0.337 ENSMUST00000037315.6
Abhd2
abhydrolase domain containing 2
chr13_-_114458720 0.337 ENSMUST00000022287.5
Fst
follistatin

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 9.1 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.8 3.2 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.8 3.1 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.7 5.6 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.5 1.5 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.5 1.9 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.5 2.7 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) phosphate ion transmembrane transport(GO:0035435) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.4 5.8 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.3 2.8 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.3 1.0 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.3 1.0 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.3 0.9 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.3 0.8 GO:1902605 heterotrimeric G-protein complex assembly(GO:1902605)
0.3 0.8 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.2 1.2 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.2 1.9 GO:0050957 equilibrioception(GO:0050957)
0.2 0.7 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.2 0.7 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.2 5.4 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.2 1.5 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091) negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.2 0.6 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.2 0.6 GO:2000851 corticosterone secretion(GO:0035934) positive regulation of glucocorticoid secretion(GO:2000851) regulation of corticosterone secretion(GO:2000852)
0.2 0.4 GO:0009838 abscission(GO:0009838)
0.2 1.2 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.2 0.8 GO:0015825 L-serine transport(GO:0015825)
0.2 1.2 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.2 0.8 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.2 0.9 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.2 1.6 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.2 0.5 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.2 0.6 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 1.2 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.1 0.4 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.1 1.1 GO:0098707 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.1 0.7 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 0.5 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.1 0.4 GO:0060023 soft palate development(GO:0060023)
0.1 0.4 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.1 0.4 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1 0.6 GO:0070627 ferrous iron import(GO:0070627)
0.1 0.3 GO:1900149 positive regulation of Schwann cell migration(GO:1900149)
0.1 0.3 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.6 GO:0072506 phosphate ion homeostasis(GO:0055062) divalent inorganic anion homeostasis(GO:0072505) trivalent inorganic anion homeostasis(GO:0072506)
0.1 0.4 GO:0010749 regulation of nitric oxide mediated signal transduction(GO:0010749)
0.1 1.1 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 0.4 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.1 0.5 GO:0015867 ATP transport(GO:0015867)
0.1 1.0 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.1 0.3 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 0.4 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.1 0.4 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 0.8 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 0.4 GO:0060690 epithelial cell differentiation involved in salivary gland development(GO:0060690)
0.1 0.3 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 0.5 GO:0016198 axon choice point recognition(GO:0016198)
0.1 4.0 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 0.2 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 0.6 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
0.1 0.2 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 2.2 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 0.5 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.2 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.1 0.5 GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.1 5.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.1 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1 1.3 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.1 0.7 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.8 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 0.9 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 0.6 GO:0035095 behavioral response to nicotine(GO:0035095)
0.1 0.4 GO:0030242 pexophagy(GO:0030242)
0.1 0.5 GO:0010715 regulation of extracellular matrix disassembly(GO:0010715)
0.1 0.2 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.1 2.7 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.1 0.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.9 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.1 0.4 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.1 1.7 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.3 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.8 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.6 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 1.4 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.2 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.2 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 1.8 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.8 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.1 GO:2000510 positive regulation of dendritic cell chemotaxis(GO:2000510)
0.0 1.3 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.6 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.3 GO:0032570 response to progesterone(GO:0032570)
0.0 0.3 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 1.1 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.2 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0 0.1 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.6 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.3 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.4 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.2 GO:0006689 ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.0 0.7 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.4 GO:0033572 transferrin transport(GO:0033572)
0.0 0.4 GO:0044144 regulation of growth of symbiont in host(GO:0044126) modulation of growth of symbiont involved in interaction with host(GO:0044144)
0.0 0.2 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 1.3 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.9 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.2 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.3 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.1 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0 0.1 GO:0030862 neuroblast division in subventricular zone(GO:0021849) positive regulation of polarized epithelial cell differentiation(GO:0030862)
0.0 0.9 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 2.6 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.3 GO:0086016 AV node cell action potential(GO:0086016) AV node cell to bundle of His cell signaling(GO:0086027)
0.0 0.5 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.5 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 0.6 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.5 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.4 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.1 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 2.2 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 0.1 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.6 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 1.7 GO:0030048 actin filament-based movement(GO:0030048)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 1.2 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.1 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.0 0.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.2 GO:0007625 grooming behavior(GO:0007625)
0.0 0.1 GO:0030035 microspike assembly(GO:0030035)
0.0 0.3 GO:0001953 negative regulation of cell-matrix adhesion(GO:0001953)
0.0 0.1 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 1.8 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.3 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.1 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.5 GO:0006284 base-excision repair(GO:0006284)
0.0 0.3 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288) regulation of stem cell population maintenance(GO:2000036)
0.0 0.1 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 1.8 GO:0035264 multicellular organism growth(GO:0035264)
0.0 0.7 GO:0030168 platelet activation(GO:0030168)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.3 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.3 1.4 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.2 0.4 GO:0005859 muscle myosin complex(GO:0005859)
0.2 3.1 GO:0005640 nuclear outer membrane(GO:0005640)
0.2 1.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.2 0.8 GO:0033093 Weibel-Palade body(GO:0033093)
0.2 0.6 GO:0060187 cell pole(GO:0060187)
0.2 2.7 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.2 0.8 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.1 0.6 GO:0097450 astrocyte end-foot(GO:0097450)
0.1 1.1 GO:0097433 dense body(GO:0097433)
0.1 1.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 2.8 GO:0071565 nBAF complex(GO:0071565)
0.1 0.6 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.9 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.1 0.3 GO:0055087 Ski complex(GO:0055087)
0.1 1.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.3 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 1.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 1.0 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 3.8 GO:0031672 A band(GO:0031672)
0.1 0.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.6 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.7 GO:0001739 sex chromatin(GO:0001739)
0.1 1.2 GO:0031045 dense core granule(GO:0031045)
0.1 0.3 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.1 0.3 GO:0060091 kinocilium(GO:0060091)
0.1 0.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.3 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.4 GO:0090543 Flemming body(GO:0090543)
0.0 1.9 GO:0032420 stereocilium(GO:0032420)
0.0 0.5 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.2 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 1.2 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.2 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 1.0 GO:0030673 axolemma(GO:0030673)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 6.1 GO:0030426 growth cone(GO:0030426)
0.0 1.1 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.4 GO:0005844 polysome(GO:0005844)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.1 GO:0030427 site of polarized growth(GO:0030427)
0.0 0.7 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 2.5 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 0.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.8 GO:0005882 intermediate filament(GO:0005882)
0.0 0.0 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.5 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.9 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.7 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.4 GO:0016235 aggresome(GO:0016235)
0.0 3.7 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.2 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.4 2.8 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2 0.9 GO:0004966 galanin receptor activity(GO:0004966)
0.2 3.6 GO:0050692 DBD domain binding(GO:0050692)
0.2 3.1 GO:0043495 protein anchor(GO:0043495)
0.2 1.0 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.2 1.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.2 1.2 GO:0034056 estrogen response element binding(GO:0034056)
0.2 1.1 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.2 0.5 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.1 0.8 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.5 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.8 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 1.5 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 0.6 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 1.2 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 1.5 GO:0002162 dystroglycan binding(GO:0002162)
0.1 1.0 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.8 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) L-proline transmembrane transporter activity(GO:0015193) alanine transmembrane transporter activity(GO:0022858)
0.1 0.4 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.1 1.0 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.4 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.9 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 1.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 0.5 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.6 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.5 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.1 0.4 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 1.7 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.6 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 3.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.9 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.7 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 1.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.6 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.3 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 1.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.5 GO:0035004 1-phosphatidylinositol-3-kinase activity(GO:0016303) phosphatidylinositol 3-kinase activity(GO:0035004)
0.0 1.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 3.6 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.4 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 1.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.3 GO:0048185 activin binding(GO:0048185)
0.0 2.7 GO:0002039 p53 binding(GO:0002039)
0.0 1.4 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.7 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.0 8.0 GO:0008017 microtubule binding(GO:0008017)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.4 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.9 GO:0070412 R-SMAD binding(GO:0070412)
0.0 7.7 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 1.3 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 3.2 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.0 1.8 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 1.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.4 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0004954 icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)
0.0 0.3 GO:0017166 vinculin binding(GO:0017166)
0.0 0.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.4 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 2.7 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.7 GO:0032452 histone demethylase activity(GO:0032452)
0.0 1.2 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.5 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.3 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.8 GO:0005179 hormone activity(GO:0005179)
0.0 0.9 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 1.2 GO:0005125 cytokine activity(GO:0005125)
0.0 7.9 GO:0008270 zinc ion binding(GO:0008270)
0.0 5.6 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.5 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0005521 lamin binding(GO:0005521)
0.0 1.3 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 1.8 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.1 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 9.1 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 5.9 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 2.2 PID_ARF6_PATHWAY Arf6 signaling events
0.1 1.4 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.1 1.0 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.0 2.0 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 2.5 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.4 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.0 1.0 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 2.0 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 0.6 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.7 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.2 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.0 0.2 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.6 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.2 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.0 0.6 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 0.4 PID_REELIN_PATHWAY Reelin signaling pathway
0.0 0.4 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.3 PID_FOXO_PATHWAY FoxO family signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.1 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.8 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.1 0.8 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 1.4 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 0.6 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 1.1 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.1 1.0 REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS Genes involved in Prolonged ERK activation events
0.0 0.5 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.0 1.4 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.0 REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 5.9 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions
0.0 0.2 REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.8 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.1 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.4 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.0 0.8 REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.9 REACTOME_REGULATORY_RNA_PATHWAYS Genes involved in Regulatory RNA pathways
0.0 1.3 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.8 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.4 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 1.0 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.4 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.6 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.3 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.2 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.8 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.6 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.1 REACTOME_ACYL_CHAIN_REMODELLING_OF_PI Genes involved in Acyl chain remodelling of PI
0.0 0.3 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 1.5 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.4 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 1.0 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.6 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.5 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.3 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.6 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.1 REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.1 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling