Motif ID: E2f3

Z-value: 0.940


Transcription factors associated with E2f3:

Gene SymbolEntrez IDGene Name
E2f3 ENSMUSG00000016477.11 E2f3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
E2f3mm10_v2_chr13_-_29984219_299843530.287.9e-02Click!


Activity profile for motif E2f3.

activity profile for motif E2f3


Sorted Z-values histogram for motif E2f3

Sorted Z-values for motif E2f3



Network of associatons between targets according to the STRING database.



First level regulatory network of E2f3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_137314394 6.820 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
Ebf3



early B cell factor 3



chr5_+_114568016 4.826 ENSMUST00000043650.7
Fam222a
family with sequence similarity 222, member A
chr11_-_100759942 4.493 ENSMUST00000107363.2
Kcnh4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr4_+_46450892 3.676 ENSMUST00000102926.4
Anp32b
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr6_+_7555053 3.196 ENSMUST00000090679.2
ENSMUST00000184986.1
Tac1

tachykinin 1

chr11_-_100759740 3.055 ENSMUST00000107361.2
Kcnh4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr1_+_187609028 2.837 ENSMUST00000110939.1
Esrrg
estrogen-related receptor gamma
chr5_-_100719675 2.632 ENSMUST00000112908.1
ENSMUST00000045617.8
Hpse

heparanase

chr19_+_41482632 2.339 ENSMUST00000067795.5
Lcor
ligand dependent nuclear receptor corepressor
chr19_+_53944870 2.229 ENSMUST00000025932.7
Shoc2
soc-2 (suppressor of clear) homolog (C. elegans)
chr10_+_50895651 2.177 ENSMUST00000020071.3
Sim1
single-minded homolog 1 (Drosophila)
chr18_+_11657349 2.107 ENSMUST00000047322.6
Rbbp8
retinoblastoma binding protein 8
chr2_+_109280738 2.088 ENSMUST00000028527.7
Kif18a
kinesin family member 18A
chr12_+_24708241 1.987 ENSMUST00000020980.5
Rrm2
ribonucleotide reductase M2
chr10_+_20347788 1.906 ENSMUST00000169712.1
Mtfr2
mitochondrial fission regulator 2
chr5_-_45857473 1.879 ENSMUST00000016026.7
ENSMUST00000067997.6
ENSMUST00000045586.6
Lcorl


ligand dependent nuclear receptor corepressor-like


chr19_+_21778325 1.840 ENSMUST00000096194.2
ENSMUST00000025663.6
Tmem2

transmembrane protein 2

chr3_+_69004969 1.795 ENSMUST00000136502.1
ENSMUST00000107803.1
Smc4

structural maintenance of chromosomes 4

chr2_-_127133909 1.786 ENSMUST00000110387.3
Ncaph
non-SMC condensin I complex, subunit H
chr15_+_102296256 1.708 ENSMUST00000064924.4
Espl1
extra spindle poles-like 1 (S. cerevisiae)
chr3_+_69004711 1.684 ENSMUST00000042901.8
Smc4
structural maintenance of chromosomes 4
chr7_-_75309262 1.677 ENSMUST00000165175.1
Sv2b
synaptic vesicle glycoprotein 2 b
chrX_-_51205773 1.523 ENSMUST00000114875.1
Mbnl3
muscleblind-like 3 (Drosophila)
chrX_-_53269786 1.487 ENSMUST00000114841.1
ENSMUST00000071023.5
Fam122b

family with sequence similarity 122, member B

chrX_-_49288229 1.480 ENSMUST00000114918.2
ENSMUST00000033437.8
ENSMUST00000114912.1
ENSMUST00000114911.1
Enox2



ecto-NOX disulfide-thiol exchanger 2



chr4_+_115000156 1.467 ENSMUST00000030490.6
Stil
Scl/Tal1 interrupting locus
chr9_+_102717668 1.423 ENSMUST00000035121.7
Amotl2
angiomotin-like 2
chr4_+_43957678 1.405 ENSMUST00000107855.1
Glipr2
GLI pathogenesis-related 2
chr16_+_17489600 1.400 ENSMUST00000115685.1
Aifm3
apoptosis-inducing factor, mitochondrion-associated 3
chr7_+_13278778 1.343 ENSMUST00000098814.4
ENSMUST00000146998.1
ENSMUST00000185145.1
Lig1


ligase I, DNA, ATP-dependent


chr7_-_6730412 1.336 ENSMUST00000051209.4
Peg3
paternally expressed 3
chr19_+_53600377 1.282 ENSMUST00000025930.9
Smc3
structural maintenance of chromosomes 3
chr9_-_79793507 1.255 ENSMUST00000120690.1
Tmem30a
transmembrane protein 30A
chr13_+_8885937 1.247 ENSMUST00000177397.1
ENSMUST00000177400.1
ENSMUST00000177447.1
Idi1


isopentenyl-diphosphate delta isomerase


chr11_-_101551837 1.215 ENSMUST00000017290.4
Brca1
breast cancer 1
chrX_-_49288195 1.207 ENSMUST00000114914.1
Enox2
ecto-NOX disulfide-thiol exchanger 2
chr12_+_112146187 1.205 ENSMUST00000128402.2
Kif26a
kinesin family member 26A
chr17_-_67354459 1.181 ENSMUST00000037974.8
Ptprm
protein tyrosine phosphatase, receptor type, M
chr2_-_37703845 1.149 ENSMUST00000155237.1
Strbp
spermatid perinuclear RNA binding protein
chr1_+_127774164 1.144 ENSMUST00000027587.8
ENSMUST00000112570.1
Ccnt2

cyclin T2

chr9_-_79793378 1.143 ENSMUST00000034878.5
Tmem30a
transmembrane protein 30A
chr5_+_32611171 1.120 ENSMUST00000072311.6
ENSMUST00000168707.2
Yes1

Yamaguchi sarcoma viral (v-yes) oncogene homolog 1

chr13_+_84222286 1.119 ENSMUST00000057495.8
Tmem161b
transmembrane protein 161B
chr4_+_115000174 1.106 ENSMUST00000129957.1
Stil
Scl/Tal1 interrupting locus
chr3_+_41742615 1.096 ENSMUST00000146165.1
ENSMUST00000119572.1
ENSMUST00000108065.2
ENSMUST00000120167.1
ENSMUST00000026867.7
ENSMUST00000026868.7
D3Ertd751e





DNA segment, Chr 3, ERATO Doi 751, expressed





chr12_-_69228167 1.083 ENSMUST00000021359.5
Pole2
polymerase (DNA directed), epsilon 2 (p59 subunit)
chrX_+_135993820 1.067 ENSMUST00000058119.7
Arxes2
adipocyte-related X-chromosome expressed sequence 2
chr19_+_40894692 1.058 ENSMUST00000050092.6
Zfp518a
zinc finger protein 518A
chr9_-_39603635 1.056 ENSMUST00000119722.1
AW551984
expressed sequence AW551984
chr6_-_51469869 1.020 ENSMUST00000114459.1
ENSMUST00000069949.6
Hnrnpa2b1

heterogeneous nuclear ribonucleoprotein A2/B1

chr11_+_21239279 0.984 ENSMUST00000006221.7
ENSMUST00000109578.1
Vps54

vacuolar protein sorting 54 (yeast)

chr13_+_117220584 0.971 ENSMUST00000022242.7
Emb
embigin
chr4_+_117096049 0.959 ENSMUST00000030443.5
Ptch2
patched homolog 2
chr16_-_4719148 0.945 ENSMUST00000115851.3
Nmral1
NmrA-like family domain containing 1
chr11_+_94741782 0.932 ENSMUST00000021240.6
Cdc34-ps
cell division cycle 34 homolog, pseudogene (S. cerevisiae)
chr19_+_56874249 0.915 ENSMUST00000026068.7
Vwa2
von Willebrand factor A domain containing 2
chr4_+_34614940 0.906 ENSMUST00000029968.7
ENSMUST00000148519.1
Rars2

arginyl-tRNA synthetase 2, mitochondrial

chr12_-_11265768 0.905 ENSMUST00000166117.1
Gen1
Gen homolog 1, endonuclease (Drosophila)
chr5_-_108132541 0.888 ENSMUST00000119437.1
ENSMUST00000118036.1
Tmed5

transmembrane emp24 protein transport domain containing 5

chr3_-_41742471 0.888 ENSMUST00000026866.8
Sclt1
sodium channel and clathrin linker 1
chr15_-_79605084 0.887 ENSMUST00000023065.6
Dmc1
DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination
chr3_-_84155762 0.876 ENSMUST00000047368.6
Mnd1
meiotic nuclear divisions 1 homolog (S. cerevisiae)
chr9_-_20976762 0.875 ENSMUST00000054197.5
S1pr2
sphingosine-1-phosphate receptor 2
chr16_-_4719078 0.867 ENSMUST00000120056.1
ENSMUST00000074970.7
Nmral1

NmrA-like family domain containing 1

chr19_+_5068077 0.863 ENSMUST00000070630.6
Cd248
CD248 antigen, endosialin
chr17_+_26917091 0.830 ENSMUST00000078961.4
Kifc5b
kinesin family member C5B
chr17_-_74294834 0.828 ENSMUST00000078459.6
Memo1
mediator of cell motility 1
chr1_+_44147847 0.826 ENSMUST00000027214.3
Ercc5
excision repair cross-complementing rodent repair deficiency, complementation group 5
chr8_+_57488053 0.825 ENSMUST00000180690.1
2500002B13Rik
RIKEN cDNA 2500002B13 gene
chr6_-_51469836 0.820 ENSMUST00000090002.7
Hnrnpa2b1
heterogeneous nuclear ribonucleoprotein A2/B1
chr8_+_34807287 0.798 ENSMUST00000033930.4
Dusp4
dual specificity phosphatase 4
chr1_-_134079114 0.782 ENSMUST00000020692.6
Btg2
B cell translocation gene 2, anti-proliferative
chr3_+_59006978 0.753 ENSMUST00000040325.7
ENSMUST00000164225.1
ENSMUST00000040846.8
ENSMUST00000029393.8
Med12l



mediator of RNA polymerase II transcription, subunit 12 homolog (yeast)-like



chrX_-_51205990 0.728 ENSMUST00000114876.2
Mbnl3
muscleblind-like 3 (Drosophila)
chr1_+_139422196 0.728 ENSMUST00000039867.7
Zbtb41
zinc finger and BTB domain containing 41 homolog
chr2_+_128818104 0.723 ENSMUST00000110325.1
Tmem87b
transmembrane protein 87B
chr9_+_64281575 0.722 ENSMUST00000034964.6
Tipin
timeless interacting protein
chr5_+_5573952 0.719 ENSMUST00000101627.2
Gm8773
predicted gene 8773
chr4_+_33031371 0.718 ENSMUST00000124992.1
Ube2j1
ubiquitin-conjugating enzyme E2J 1
chr2_+_103969528 0.715 ENSMUST00000123437.1
ENSMUST00000163256.1
Lmo2

LIM domain only 2

chr16_+_43889896 0.715 ENSMUST00000122014.1
ENSMUST00000178400.1
2610015P09Rik

RIKEN cDNA 2610015P09 gene

chr5_+_72914554 0.714 ENSMUST00000143829.1
Slain2
SLAIN motif family, member 2
chr5_-_108132577 0.713 ENSMUST00000061203.6
ENSMUST00000002837.4
Tmed5

transmembrane emp24 protein transport domain containing 5

chr5_+_74535449 0.671 ENSMUST00000080164.5
ENSMUST00000113536.1
ENSMUST00000122245.1
ENSMUST00000120618.1
ENSMUST00000113535.2
ENSMUST00000113534.2
Fip1l1





FIP1 like 1 (S. cerevisiae)





chr3_-_127553233 0.654 ENSMUST00000029588.5
Larp7
La ribonucleoprotein domain family, member 7
chr17_-_80062333 0.654 ENSMUST00000061331.7
Hnrnpll
heterogeneous nuclear ribonucleoprotein L-like
chr8_-_57487801 0.653 ENSMUST00000034022.3
Sap30
sin3 associated polypeptide
chr4_+_33924632 0.650 ENSMUST00000057188.6
Cnr1
cannabinoid receptor 1 (brain)
chr16_+_43889800 0.650 ENSMUST00000132859.1
2610015P09Rik
RIKEN cDNA 2610015P09 gene
chr5_-_65697856 0.650 ENSMUST00000031104.6
Pds5a
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr6_+_85187438 0.647 ENSMUST00000045942.8
Emx1
empty spiracles homeobox 1
chr12_+_4917376 0.645 ENSMUST00000045664.5
Atad2b
ATPase family, AAA domain containing 2B
chr16_+_34690548 0.642 ENSMUST00000023532.6
Ccdc14
coiled-coil domain containing 14
chr8_+_105860634 0.623 ENSMUST00000008594.7
Nutf2
nuclear transport factor 2
chr12_+_11265867 0.623 ENSMUST00000020931.5
Smc6
structural maintenance of chromosomes 6
chr12_-_21373606 0.619 ENSMUST00000064536.6
Adam17
a disintegrin and metallopeptidase domain 17
chr18_+_44380479 0.614 ENSMUST00000025350.8
Dcp2
DCP2 decapping enzyme homolog (S. cerevisiae)
chr5_+_74535535 0.608 ENSMUST00000121950.1
Fip1l1
FIP1 like 1 (S. cerevisiae)
chr18_+_73863672 0.601 ENSMUST00000134847.1
Mro
maestro
chr9_-_98601642 0.599 ENSMUST00000035034.8
Mrps22
mitochondrial ribosomal protein S22
chr12_-_21373550 0.588 ENSMUST00000101551.3
Adam17
a disintegrin and metallopeptidase domain 17
chr2_+_102659213 0.565 ENSMUST00000111213.1
Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr6_-_71440623 0.547 ENSMUST00000002292.8
Rmnd5a
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr14_+_8214135 0.545 ENSMUST00000022272.6
Kctd6
potassium channel tetramerisation domain containing 6
chr9_-_105495130 0.540 ENSMUST00000038118.7
Atp2c1
ATPase, Ca++-sequestering
chr9_-_72985344 0.516 ENSMUST00000124565.2
Gm5918
predicted gene 5918
chr14_-_13961202 0.514 ENSMUST00000065865.8
Thoc7
THO complex 7 homolog (Drosophila)
chr5_+_108132885 0.511 ENSMUST00000047677.7
Ccdc18
coiled-coil domain containing 18
chr16_-_78376758 0.509 ENSMUST00000023570.7
Btg3
B cell translocation gene 3
chr12_-_4874341 0.503 ENSMUST00000137337.1
ENSMUST00000045921.7
Mfsd2b

major facilitator superfamily domain containing 2B

chr17_+_35841668 0.496 ENSMUST00000174124.1
Mdc1
mediator of DNA damage checkpoint 1
chr17_-_80062199 0.470 ENSMUST00000184635.1
Hnrnpll
heterogeneous nuclear ribonucleoprotein L-like
chr2_+_16356744 0.469 ENSMUST00000114703.3
Plxdc2
plexin domain containing 2
chr7_+_28808795 0.462 ENSMUST00000172529.1
Hnrnpl
heterogeneous nuclear ribonucleoprotein L
chr14_-_60251473 0.453 ENSMUST00000041905.6
Nupl1
nucleoporin like 1
chr1_+_191906743 0.448 ENSMUST00000044954.6
Slc30a1
solute carrier family 30 (zinc transporter), member 1
chr9_+_44240668 0.447 ENSMUST00000092426.3
Ccdc153
coiled-coil domain containing 153
chr10_-_30600662 0.445 ENSMUST00000019927.6
Trmt11
tRNA methyltransferase 11
chr4_+_32615473 0.443 ENSMUST00000178925.1
ENSMUST00000029950.3
Casp8ap2

caspase 8 associated protein 2

chr3_-_95217690 0.440 ENSMUST00000107209.1
Gabpb2
GA repeat binding protein, beta 2
chr14_-_30626196 0.439 ENSMUST00000112210.3
ENSMUST00000112211.2
ENSMUST00000112208.1
Prkcd


protein kinase C, delta


chr5_-_108132513 0.426 ENSMUST00000119784.1
ENSMUST00000117759.1
Tmed5

transmembrane emp24 protein transport domain containing 5

chr17_+_35841491 0.424 ENSMUST00000082337.6
Mdc1
mediator of DNA damage checkpoint 1
chr3_-_69004565 0.415 ENSMUST00000169064.1
Ift80
intraflagellar transport 80
chr2_+_115581667 0.413 ENSMUST00000166472.1
ENSMUST00000110918.2
BC052040

cDNA sequence BC052040

chr13_-_21531084 0.411 ENSMUST00000045228.5
Zkscan8
zinc finger with KRAB and SCAN domains 8
chr1_-_191575534 0.410 ENSMUST00000027933.5
Dtl
denticleless homolog (Drosophila)
chr6_+_29768443 0.407 ENSMUST00000166718.1
ENSMUST00000102995.2
ENSMUST00000115242.2
Ahcyl2


S-adenosylhomocysteine hydrolase-like 2


chr14_-_54864055 0.401 ENSMUST00000142283.2
Homez
homeodomain leucine zipper-encoding gene
chr2_+_150909565 0.397 ENSMUST00000028948.4
Gins1
GINS complex subunit 1 (Psf1 homolog)
chr12_+_80945520 0.396 ENSMUST00000110354.1
ENSMUST00000110352.3
ENSMUST00000110351.1
ENSMUST00000110356.2
Srsf5



serine/arginine-rich splicing factor 5



chr3_-_84480419 0.395 ENSMUST00000107689.1
Fhdc1
FH2 domain containing 1
chrX_+_103356464 0.387 ENSMUST00000116547.2
Chic1
cysteine-rich hydrophobic domain 1
chr12_-_69681795 0.384 ENSMUST00000183277.1
ENSMUST00000035773.7
Sos2

son of sevenless homolog 2 (Drosophila)

chr7_+_113513854 0.384 ENSMUST00000067929.8
ENSMUST00000129087.1
ENSMUST00000164745.1
ENSMUST00000136158.1
Far1



fatty acyl CoA reductase 1



chr5_-_33936301 0.382 ENSMUST00000030993.6
Nelfa
negative elongation factor complex member A, Whsc2
chr7_+_113513829 0.379 ENSMUST00000033018.8
Far1
fatty acyl CoA reductase 1
chr1_-_135313691 0.377 ENSMUST00000134088.1
ENSMUST00000081104.3
Timm17a

translocase of inner mitochondrial membrane 17a

chr17_+_34398802 0.375 ENSMUST00000114175.1
ENSMUST00000078615.5
ENSMUST00000139063.1
ENSMUST00000097348.2
BC051142



cDNA sequence BC051142



chr17_+_29032664 0.357 ENSMUST00000130216.1
Srsf3
serine/arginine-rich splicing factor 3
chr2_+_144556229 0.357 ENSMUST00000143573.1
ENSMUST00000028916.8
ENSMUST00000155258.1
Sec23b


SEC23B (S. cerevisiae)


chr1_-_16619245 0.352 ENSMUST00000182984.1
ENSMUST00000182554.1
Ube2w

ubiquitin-conjugating enzyme E2W (putative)

chr12_+_111538819 0.350 ENSMUST00000050993.9
Eif5
eukaryotic translation initiation factor 5
chr1_-_66863265 0.346 ENSMUST00000027153.5
Acadl
acyl-Coenzyme A dehydrogenase, long-chain
chr11_-_86544754 0.339 ENSMUST00000138810.1
ENSMUST00000058286.2
ENSMUST00000154617.1
Rps6kb1


ribosomal protein S6 kinase, polypeptide 1


chrX_-_44790179 0.337 ENSMUST00000060481.2
Dcaf12l1
DDB1 and CUL4 associated factor 12-like 1
chr11_-_120796369 0.333 ENSMUST00000143139.1
ENSMUST00000129955.1
ENSMUST00000026151.4
ENSMUST00000167023.1
ENSMUST00000106133.1
ENSMUST00000106135.1
Dus1l





dihydrouridine synthase 1-like (S. cerevisiae)





chr9_-_96631487 0.328 ENSMUST00000128346.1
ENSMUST00000034984.6
Rasa2

RAS p21 protein activator 2

chr16_+_43889936 0.320 ENSMUST00000151183.1
2610015P09Rik
RIKEN cDNA 2610015P09 gene
chr3_-_69004503 0.310 ENSMUST00000107812.1
Ift80
intraflagellar transport 80
chr8_-_45333189 0.308 ENSMUST00000095328.4
Cyp4v3
cytochrome P450, family 4, subfamily v, polypeptide 3
chr2_+_76675265 0.299 ENSMUST00000111920.1
Plekha3
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 3
chr1_-_16619437 0.295 ENSMUST00000117146.1
Ube2w
ubiquitin-conjugating enzyme E2W (putative)
chr10_-_61784014 0.290 ENSMUST00000020283.4
H2afy2
H2A histone family, member Y2
chr11_+_115564434 0.289 ENSMUST00000021085.4
Nup85
nucleoporin 85
chr13_-_9764943 0.286 ENSMUST00000110634.1
Zmynd11
zinc finger, MYND domain containing 11
chr7_+_90130227 0.280 ENSMUST00000049537.7
Picalm
phosphatidylinositol binding clathrin assembly protein
chr11_+_67025144 0.275 ENSMUST00000079077.5
ENSMUST00000061786.5
Tmem220

transmembrane protein 220

chr3_-_69004475 0.274 ENSMUST00000154741.1
ENSMUST00000148031.1
Ift80

intraflagellar transport 80

chr18_-_65939048 0.264 ENSMUST00000025396.3
Rax
retina and anterior neural fold homeobox
chr3_-_95217877 0.260 ENSMUST00000136139.1
Gabpb2
GA repeat binding protein, beta 2
chr6_+_57580992 0.259 ENSMUST00000031817.8
Herc6
hect domain and RLD 6
chr9_+_103112072 0.254 ENSMUST00000035155.6
Rab6b
RAB6B, member RAS oncogene family
chr15_+_84232030 0.253 ENSMUST00000023072.6
Parvb
parvin, beta
chr17_+_69417441 0.251 ENSMUST00000097289.2
C030034I22Rik
RIKEN cDNA C030034I22 gene
chr7_-_142372210 0.248 ENSMUST00000084412.5
Ifitm10
interferon induced transmembrane protein 10
chr4_+_131843459 0.246 ENSMUST00000030742.4
ENSMUST00000137321.1
Mecr

mitochondrial trans-2-enoyl-CoA reductase

chr2_-_103797617 0.244 ENSMUST00000028607.6
Caprin1
cell cycle associated protein 1
chr9_+_56041857 0.244 ENSMUST00000114276.2
Rcn2
reticulocalbin 2
chr9_-_62980874 0.239 ENSMUST00000098651.4
Pias1
protein inhibitor of activated STAT 1
chr2_+_31670714 0.230 ENSMUST00000038474.7
ENSMUST00000137156.1
Exosc2

exosome component 2

chr10_-_62449738 0.227 ENSMUST00000020273.9
Supv3l1
suppressor of var1, 3-like 1 (S. cerevisiae)
chr9_+_108854024 0.226 ENSMUST00000098376.3
Slc26a6
solute carrier family 26, member 6
chr1_-_97661950 0.226 ENSMUST00000053033.7
ENSMUST00000149927.1
D1Ertd622e

DNA segment, Chr 1, ERATO Doi 622, expressed

chr7_-_44257378 0.223 ENSMUST00000107945.1
ENSMUST00000118216.1
Acpt

acid phosphatase, testicular

chrX_-_48454152 0.223 ENSMUST00000114958.1
Elf4
E74-like factor 4 (ets domain transcription factor)
chr10_-_91123955 0.212 ENSMUST00000164505.1
ENSMUST00000170810.1
ENSMUST00000076694.6
Slc25a3


solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3


chr13_-_21402688 0.202 ENSMUST00000117721.1
ENSMUST00000070785.8
ENSMUST00000116433.1
ENSMUST00000116434.3
Zkscan3



zinc finger with KRAB and SCAN domains 3



chr13_+_55445301 0.200 ENSMUST00000001115.8
ENSMUST00000099482.3
Grk6

G protein-coupled receptor kinase 6

chr4_+_155812489 0.199 ENSMUST00000030944.4
Ccnl2
cyclin L2
chr13_-_9765137 0.193 ENSMUST00000062658.8
ENSMUST00000130151.1
ENSMUST00000110636.1
ENSMUST00000152725.1
Zmynd11



zinc finger, MYND domain containing 11



chr7_+_133637686 0.187 ENSMUST00000128901.2
2700050L05Rik
RIKEN cDNA 2700050L05 gene
chr17_+_50509518 0.182 ENSMUST00000043938.6
Plcl2
phospholipase C-like 2
chr13_+_45078692 0.178 ENSMUST00000054395.6
Gm9817
predicted gene 9817
chr4_-_34614886 0.177 ENSMUST00000140334.1
ENSMUST00000108142.1
ENSMUST00000048706.3
Orc3


origin recognition complex, subunit 3


chr6_+_47454320 0.165 ENSMUST00000031697.8
Cul1
cullin 1
chr16_+_91647859 0.165 ENSMUST00000119368.1
ENSMUST00000114037.2
ENSMUST00000114036.2
ENSMUST00000122302.1
Son



Son DNA binding protein



chrX_-_102189371 0.164 ENSMUST00000033683.7
Rps4x
ribosomal protein S4, X-linked
chr19_+_32485751 0.164 ENSMUST00000025827.8
Minpp1
multiple inositol polyphosphate histidine phosphatase 1
chr16_-_43889669 0.160 ENSMUST00000023387.7
Qtrtd1
queuine tRNA-ribosyltransferase domain containing 1
chr8_-_107048573 0.151 ENSMUST00000055316.9
Pdf
peptide deformylase (mitochondrial)
chr2_-_25224653 0.151 ENSMUST00000043584.4
Tubb4b
tubulin, beta 4B class IVB
chr13_-_55329723 0.148 ENSMUST00000021941.7
Mxd3
Max dimerization protein 3
chr7_-_116334132 0.144 ENSMUST00000170953.1
Rps13
ribosomal protein S13
chr9_+_109875541 0.144 ENSMUST00000094324.3
Cdc25a
cell division cycle 25A
chr4_-_133967235 0.143 ENSMUST00000123234.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr19_-_9559204 0.140 ENSMUST00000090527.3
Stxbp3b
syntaxin-binding protein 3B
chr1_-_97661668 0.135 ENSMUST00000153115.1
ENSMUST00000142234.1
D1Ertd622e

DNA segment, Chr 1, ERATO Doi 622, expressed

chrX_+_101274023 0.134 ENSMUST00000117706.1
Med12
mediator of RNA polymerase II transcription, subunit 12 homolog (yeast)
chrX_+_101274198 0.134 ENSMUST00000117203.1
ENSMUST00000087948.4
ENSMUST00000087956.5
Med12


mediator of RNA polymerase II transcription, subunit 12 homolog (yeast)



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0035934 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.9 2.6 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.7 5.3 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.4 2.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.4 1.2 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.4 1.1 GO:0019085 early viral transcription(GO:0019085)
0.3 2.4 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.3 1.8 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.3 1.2 GO:0035624 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) response to high density lipoprotein particle(GO:0055099)
0.3 0.9 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.3 1.8 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.3 0.8 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.2 1.0 GO:0009957 epidermal cell fate specification(GO:0009957)
0.2 2.1 GO:0033504 floor plate development(GO:0033504)
0.2 0.9 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.2 1.1 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.2 1.2 GO:0046490 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
0.2 0.6 GO:0090204 protein localization to nuclear pore(GO:0090204) negative regulation of vascular endothelial growth factor production(GO:1904046)
0.2 1.3 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
0.2 1.1 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.2 0.9 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.2 0.7 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.2 0.7 GO:0031622 positive regulation of fever generation(GO:0031622) negative regulation of action potential(GO:0045759) trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.2 1.3 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.2 3.7 GO:0043486 histone exchange(GO:0043486)
0.2 1.7 GO:0051307 meiotic chromosome separation(GO:0051307)
0.2 0.8 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.2 2.4 GO:0006312 mitotic recombination(GO:0006312)
0.1 0.4 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.1 0.9 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 1.3 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 0.7 GO:0048478 replication fork protection(GO:0048478)
0.1 2.0 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 2.0 GO:0090161 Golgi ribbon formation(GO:0090161)
0.1 1.2 GO:0048484 enteric nervous system development(GO:0048484)
0.1 1.0 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.1 1.0 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 0.4 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.1 1.6 GO:0072520 seminiferous tubule development(GO:0072520)
0.1 2.3 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 0.3 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.1 0.3 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.1 0.6 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 0.2 GO:0035672 transepithelial chloride transport(GO:0030321) oligopeptide transmembrane transport(GO:0035672)
0.1 0.2 GO:0001787 natural killer cell proliferation(GO:0001787)
0.1 0.4 GO:0036337 Fas signaling pathway(GO:0036337)
0.1 0.7 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.1 0.7 GO:1904152 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) regulation of retrograde protein transport, ER to cytosol(GO:1904152) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 1.1 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.1 0.3 GO:0090647 modulation of age-related behavioral decline(GO:0090647) negative regulation of metalloendopeptidase activity(GO:1904684)
0.1 0.3 GO:0042758 long-chain fatty acid catabolic process(GO:0042758)
0.1 0.3 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.1 0.2 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.1 0.4 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.1 0.6 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 0.2 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.1 0.2 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 0.6 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 0.4 GO:0019985 translesion synthesis(GO:0019985)
0.1 0.2 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1 0.9 GO:0060033 anatomical structure regression(GO:0060033)
0.1 0.4 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271) mitotic DNA replication(GO:1902969)
0.1 0.2 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960) mitochondrial RNA 3'-end processing(GO:0000965)
0.1 0.8 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.1 0.7 GO:0097067 negative regulation of erythrocyte differentiation(GO:0045647) cellular response to thyroid hormone stimulus(GO:0097067)
0.1 0.9 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.1 0.6 GO:0060019 radial glial cell differentiation(GO:0060019)
0.1 2.8 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 0.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.2 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.3 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 0.5 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.5 GO:1902416 positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.0 1.2 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.4 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.0 0.6 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.4 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 1.4 GO:0035329 hippo signaling(GO:0035329)
0.0 1.9 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 1.5 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.0 0.4 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.2 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.1 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0031990 mRNA export from nucleus in response to heat stress(GO:0031990)
0.0 1.3 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.0 0.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.7 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.6 GO:0071218 cellular response to misfolded protein(GO:0071218)
0.0 0.5 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.2 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 0.5 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.1 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 1.4 GO:0097194 execution phase of apoptosis(GO:0097194)
0.0 0.4 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0 0.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 1.2 GO:0010634 positive regulation of epithelial cell migration(GO:0010634)
0.0 0.1 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.7 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.3 GO:0021854 hypothalamus development(GO:0021854)
0.0 0.1 GO:0033262 regulation of nuclear cell cycle DNA replication(GO:0033262)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0000799 nuclear condensin complex(GO:0000799)
0.5 3.5 GO:0000796 condensin complex(GO:0000796)
0.4 2.0 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.3 1.3 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.3 2.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.2 1.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.2 0.6 GO:0035061 interchromatin granule(GO:0035061)
0.2 1.2 GO:0070531 BRCA1-A complex(GO:0070531)
0.2 0.5 GO:0034657 GID complex(GO:0034657)
0.2 0.2 GO:0031261 DNA replication preinitiation complex(GO:0031261)
0.2 1.0 GO:0000938 GARP complex(GO:0000938)
0.2 2.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.2 1.8 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.1 0.7 GO:0031298 replication fork protection complex(GO:0031298)
0.1 0.4 GO:0000811 GINS complex(GO:0000811)
0.1 1.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1 0.4 GO:0032021 NELF complex(GO:0032021)
0.1 0.3 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.9 GO:0071439 clathrin complex(GO:0071439)
0.1 0.6 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 2.0 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 1.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.8 GO:0005675 holo TFIIH complex(GO:0005675)
0.1 0.4 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.8 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.1 0.5 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.6 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.4 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.3 GO:0001740 Barr body(GO:0001740)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.5 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 2.1 GO:0005871 kinesin complex(GO:0005871)
0.0 0.6 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 1.0 GO:0016592 mediator complex(GO:0016592)
0.0 0.7 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 2.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 2.4 GO:0005814 centriole(GO:0005814)
0.0 0.5 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.5 GO:0045120 pronucleus(GO:0045120)
0.0 1.3 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.6 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.6 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0045298 tubulin complex(GO:0045298)
0.0 0.2 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.4 GO:0035869 ciliary transition zone(GO:0035869)
0.0 1.0 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.9 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.8 GO:0016605 PML body(GO:0016605)
0.0 2.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 4.0 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 1.2 GO:0043195 terminal bouton(GO:0043195)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.8 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.4 2.6 GO:0045545 syndecan binding(GO:0045545)
0.4 2.0 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.4 1.2 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.3 1.3 GO:0036033 mediator complex binding(GO:0036033)
0.3 1.0 GO:0005119 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158)
0.3 1.8 GO:0001069 regulatory region RNA binding(GO:0001069)
0.3 1.8 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.2 0.9 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.2 1.3 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.2 0.6 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.2 2.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.2 0.7 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.2 0.8 GO:0000405 bubble DNA binding(GO:0000405)
0.2 3.2 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.2 0.5 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2 0.8 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.2 1.2 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.2 0.9 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 1.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 2.8 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 2.7 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 0.9 GO:0000150 recombinase activity(GO:0000150)
0.1 2.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.3 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 0.4 GO:0070976 calcium-independent protein kinase C activity(GO:0004699) TIR domain binding(GO:0070976)
0.1 0.9 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 1.2 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 0.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 7.5 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.1 0.4 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 0.3 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1 0.2 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1 0.6 GO:0050733 RS domain binding(GO:0050733)
0.1 0.3 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 0.4 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 1.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.4 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.4 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.5 GO:1990715 mRNA CDS binding(GO:1990715)
0.1 0.2 GO:0015563 uptake transmembrane transporter activity(GO:0015563)
0.1 0.4 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1 0.2 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.4 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.2 GO:0052743 inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.0 1.1 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.4 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 1.1 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 1.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.7 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 2.7 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 1.4 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 1.2 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 2.0 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.6 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 7.2 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 1.2 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 2.9 GO:0042393 histone binding(GO:0042393)
0.0 0.2 GO:0003678 DNA helicase activity(GO:0003678)
0.0 1.1 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.6 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.3 GO:0031489 myosin V binding(GO:0031489)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.7 PID_ATM_PATHWAY ATM pathway
0.1 3.5 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.1 5.3 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 1.2 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 0.9 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.0 1.6 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.4 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.2 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.2 PID_ERBB4_PATHWAY ErbB4 signaling events
0.0 1.9 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.9 PID_E2F_PATHWAY E2F transcription factor network
0.0 0.3 ST_INTERLEUKIN_4_PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.7 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 0.7 PID_ATR_PATHWAY ATR signaling pathway
0.0 0.2 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.0 2.4 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.1 PID_AR_NONGENOMIC_PATHWAY Nongenotropic Androgen signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.4 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.2 7.5 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 3.3 REACTOME_KINESINS Genes involved in Kinesins
0.1 2.6 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.1 2.1 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 1.1 REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.1 1.2 REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR Genes involved in Regulated proteolysis of p75NTR
0.1 1.1 REACTOME_PECAM1_INTERACTIONS Genes involved in PECAM1 interactions
0.1 3.9 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.1 0.1 REACTOME_AUTODEGRADATION_OF_THE_E3_UBIQUITIN_LIGASE_COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.1 0.8 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.1 1.2 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.8 REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 1.5 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 0.8 REACTOME_TRANSCRIPTION_COUPLED_NER_TC_NER Genes involved in Transcription-coupled NER (TC-NER)
0.0 1.2 REACTOME_ELONGATION_ARREST_AND_RECOVERY Genes involved in Elongation arrest and recovery
0.0 2.8 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.9 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 3.2 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.3 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.4 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.0 0.2 REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 1.2 REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 0.8 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 2.9 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.0 0.7 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.2 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.3 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.3 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.7 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.2 REACTOME_GENERIC_TRANSCRIPTION_PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.4 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.0 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)