Motif ID: Dbp
Z-value: 0.826

Transcription factors associated with Dbp:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Dbp | ENSMUSG00000059824.4 | Dbp |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Dbp | mm10_v2_chr7_+_45705518_45705624 | -0.18 | 2.5e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.4 | 4.2 | GO:0001928 | regulation of exocyst assembly(GO:0001928) |
0.9 | 2.8 | GO:0098923 | retrograde trans-synaptic signaling by soluble gas(GO:0098923) |
0.7 | 2.2 | GO:0003345 | proepicardium cell migration involved in pericardium morphogenesis(GO:0003345) |
0.6 | 1.2 | GO:0060167 | regulation of adenosine receptor signaling pathway(GO:0060167) |
0.5 | 3.1 | GO:0021797 | forebrain anterior/posterior pattern specification(GO:0021797) |
0.5 | 2.0 | GO:1904800 | regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) |
0.5 | 3.7 | GO:0061368 | maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368) |
0.5 | 1.4 | GO:0097155 | fasciculation of sensory neuron axon(GO:0097155) |
0.4 | 1.8 | GO:2000211 | regulation of glutamate metabolic process(GO:2000211) |
0.4 | 3.9 | GO:0090043 | regulation of tubulin deacetylation(GO:0090043) |
0.4 | 1.3 | GO:0032241 | positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256) |
0.4 | 2.5 | GO:0060012 | synaptic transmission, glycinergic(GO:0060012) |
0.4 | 3.6 | GO:0071420 | cellular response to histamine(GO:0071420) |
0.4 | 4.8 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
0.4 | 1.6 | GO:1905247 | positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247) |
0.4 | 3.9 | GO:0014824 | artery smooth muscle contraction(GO:0014824) |
0.4 | 1.1 | GO:0086046 | membrane depolarization during SA node cell action potential(GO:0086046) |
0.4 | 1.1 | GO:2000569 | T-helper 2 cell activation(GO:0035712) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570) |
0.4 | 1.1 | GO:0060084 | regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) synaptic transmission involved in micturition(GO:0060084) |
0.3 | 1.8 | GO:0007258 | JUN phosphorylation(GO:0007258) |
0.3 | 0.9 | GO:0061526 | acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) regulation of sulfur amino acid metabolic process(GO:0031335) musculoskeletal movement, spinal reflex action(GO:0050883) acetylcholine secretion(GO:0061526) |
0.3 | 0.5 | GO:1904020 | regulation of G-protein coupled receptor internalization(GO:1904020) |
0.2 | 0.7 | GO:0060023 | soft palate development(GO:0060023) |
0.2 | 2.8 | GO:1902993 | positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993) |
0.2 | 0.7 | GO:1902630 | regulation of membrane hyperpolarization(GO:1902630) |
0.2 | 2.0 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
0.2 | 0.6 | GO:0016115 | terpenoid catabolic process(GO:0016115) |
0.2 | 1.7 | GO:0050908 | detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962) |
0.2 | 1.3 | GO:1900042 | positive regulation of interleukin-2 secretion(GO:1900042) |
0.2 | 1.6 | GO:0035887 | aortic smooth muscle cell differentiation(GO:0035887) |
0.2 | 1.3 | GO:0060050 | positive regulation of protein glycosylation(GO:0060050) spindle assembly involved in meiosis(GO:0090306) |
0.2 | 2.0 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
0.2 | 1.9 | GO:0033089 | positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400) |
0.2 | 2.6 | GO:0021540 | corpus callosum morphogenesis(GO:0021540) corticospinal tract morphogenesis(GO:0021957) |
0.2 | 0.9 | GO:0060024 | rhythmic synaptic transmission(GO:0060024) |
0.2 | 1.1 | GO:0006344 | maintenance of chromatin silencing(GO:0006344) |
0.2 | 0.6 | GO:2000110 | protein sialylation(GO:1990743) negative regulation of macrophage apoptotic process(GO:2000110) |
0.1 | 1.2 | GO:0097264 | self proteolysis(GO:0097264) |
0.1 | 0.7 | GO:0036324 | negative regulation of toll-like receptor 4 signaling pathway(GO:0034144) vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) |
0.1 | 1.8 | GO:1902018 | negative regulation of cilium assembly(GO:1902018) |
0.1 | 0.8 | GO:2000672 | negative regulation of motor neuron apoptotic process(GO:2000672) |
0.1 | 0.4 | GO:0019482 | beta-alanine metabolic process(GO:0019482) |
0.1 | 0.2 | GO:0003357 | noradrenergic neuron differentiation(GO:0003357) |
0.1 | 0.8 | GO:0021937 | cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937) |
0.1 | 0.7 | GO:0034773 | histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368) |
0.1 | 0.6 | GO:1905150 | regulation of voltage-gated sodium channel activity(GO:1905150) |
0.1 | 2.4 | GO:0008090 | retrograde axonal transport(GO:0008090) |
0.1 | 0.3 | GO:0071707 | immunoglobulin heavy chain V-D-J recombination(GO:0071707) |
0.1 | 1.9 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
0.1 | 8.5 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
0.1 | 1.0 | GO:0070072 | vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
0.1 | 0.5 | GO:0035063 | nuclear speck organization(GO:0035063) |
0.1 | 1.3 | GO:1901898 | regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898) |
0.1 | 1.8 | GO:0010669 | epithelial structure maintenance(GO:0010669) |
0.1 | 0.6 | GO:0051964 | negative regulation of synapse assembly(GO:0051964) |
0.1 | 1.1 | GO:2000096 | positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
0.1 | 1.5 | GO:2001014 | regulation of skeletal muscle cell differentiation(GO:2001014) |
0.1 | 0.4 | GO:0019065 | receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509) |
0.1 | 1.9 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
0.1 | 0.4 | GO:0071313 | cellular response to caffeine(GO:0071313) |
0.1 | 0.4 | GO:0090070 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
0.1 | 0.2 | GO:0061386 | closure of optic fissure(GO:0061386) |
0.1 | 1.5 | GO:0051968 | positive regulation of synaptic transmission, glutamatergic(GO:0051968) |
0.1 | 1.5 | GO:0043552 | positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552) |
0.1 | 0.8 | GO:0021527 | spinal cord association neuron differentiation(GO:0021527) |
0.1 | 1.1 | GO:0021702 | cerebellar Purkinje cell differentiation(GO:0021702) |
0.1 | 0.3 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
0.1 | 0.5 | GO:0097105 | presynaptic membrane assembly(GO:0097105) |
0.1 | 0.6 | GO:0034551 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033) |
0.1 | 0.8 | GO:0043982 | histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982) |
0.1 | 2.6 | GO:0007026 | negative regulation of microtubule depolymerization(GO:0007026) |
0.1 | 1.4 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
0.1 | 1.9 | GO:0045851 | pH reduction(GO:0045851) |
0.1 | 2.4 | GO:0007218 | neuropeptide signaling pathway(GO:0007218) |
0.1 | 1.0 | GO:0046069 | cGMP catabolic process(GO:0046069) |
0.1 | 1.4 | GO:0010758 | regulation of macrophage chemotaxis(GO:0010758) |
0.1 | 1.3 | GO:0007097 | nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023) |
0.1 | 0.3 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) |
0.1 | 3.6 | GO:0060395 | SMAD protein signal transduction(GO:0060395) |
0.1 | 0.7 | GO:0007250 | activation of NF-kappaB-inducing kinase activity(GO:0007250) |
0.1 | 0.7 | GO:0060837 | blood vessel endothelial cell differentiation(GO:0060837) |
0.0 | 0.5 | GO:0060501 | positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) |
0.0 | 1.0 | GO:0071425 | hematopoietic stem cell proliferation(GO:0071425) |
0.0 | 2.0 | GO:0034605 | cellular response to heat(GO:0034605) |
0.0 | 1.7 | GO:0006376 | mRNA splice site selection(GO:0006376) |
0.0 | 0.2 | GO:0010993 | regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994) |
0.0 | 0.3 | GO:0030718 | germ-line stem cell population maintenance(GO:0030718) |
0.0 | 1.3 | GO:0051491 | positive regulation of filopodium assembly(GO:0051491) |
0.0 | 0.8 | GO:0071625 | vocalization behavior(GO:0071625) |
0.0 | 0.4 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
0.0 | 0.2 | GO:0021593 | rhombomere morphogenesis(GO:0021593) |
0.0 | 0.4 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
0.0 | 1.8 | GO:0050775 | positive regulation of dendrite morphogenesis(GO:0050775) |
0.0 | 2.9 | GO:0006487 | protein N-linked glycosylation(GO:0006487) |
0.0 | 0.4 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
0.0 | 0.2 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
0.0 | 0.9 | GO:0010569 | regulation of double-strand break repair via homologous recombination(GO:0010569) |
0.0 | 0.4 | GO:2000811 | negative regulation of anoikis(GO:2000811) |
0.0 | 0.2 | GO:0031584 | activation of phospholipase D activity(GO:0031584) |
0.0 | 3.3 | GO:0007416 | synapse assembly(GO:0007416) |
0.0 | 0.2 | GO:0043353 | enucleate erythrocyte differentiation(GO:0043353) |
0.0 | 0.1 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
0.0 | 2.2 | GO:1903955 | positive regulation of protein targeting to mitochondrion(GO:1903955) |
0.0 | 0.5 | GO:2000300 | regulation of synaptic vesicle exocytosis(GO:2000300) |
0.0 | 2.1 | GO:0048813 | dendrite morphogenesis(GO:0048813) |
0.0 | 0.8 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
0.0 | 0.9 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
0.0 | 1.3 | GO:0030968 | endoplasmic reticulum unfolded protein response(GO:0030968) |
0.0 | 0.6 | GO:2000279 | negative regulation of DNA biosynthetic process(GO:2000279) |
0.0 | 0.7 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
0.0 | 0.2 | GO:0000301 | retrograde transport, vesicle recycling within Golgi(GO:0000301) |
0.0 | 0.4 | GO:0045214 | sarcomere organization(GO:0045214) |
0.0 | 0.1 | GO:2000052 | positive regulation of non-canonical Wnt signaling pathway(GO:2000052) |
0.0 | 1.2 | GO:0001578 | microtubule bundle formation(GO:0001578) |
0.0 | 0.9 | GO:0051865 | protein autoubiquitination(GO:0051865) |
0.0 | 2.1 | GO:0071805 | potassium ion transmembrane transport(GO:0071805) |
0.0 | 0.1 | GO:1902969 | mitotic DNA replication(GO:1902969) |
0.0 | 0.3 | GO:0071539 | protein localization to centrosome(GO:0071539) |
0.0 | 0.3 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
0.0 | 0.8 | GO:0007173 | epidermal growth factor receptor signaling pathway(GO:0007173) |
0.0 | 0.3 | GO:0060043 | regulation of cardiac muscle cell proliferation(GO:0060043) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 2.4 | GO:0031673 | H zone(GO:0031673) |
0.5 | 4.5 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
0.4 | 5.5 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
0.3 | 1.3 | GO:0032437 | cuticular plate(GO:0032437) |
0.2 | 6.2 | GO:0071565 | nBAF complex(GO:0071565) |
0.2 | 1.8 | GO:0034750 | Scrib-APC-beta-catenin complex(GO:0034750) |
0.2 | 0.7 | GO:0098855 | HCN channel complex(GO:0098855) |
0.2 | 4.5 | GO:0032279 | asymmetric synapse(GO:0032279) |
0.2 | 0.7 | GO:1990032 | parallel fiber(GO:1990032) |
0.2 | 0.9 | GO:0032983 | kainate selective glutamate receptor complex(GO:0032983) |
0.1 | 1.4 | GO:0042589 | zymogen granule membrane(GO:0042589) |
0.1 | 5.6 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
0.1 | 0.3 | GO:1990812 | growth cone filopodium(GO:1990812) |
0.1 | 1.3 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
0.1 | 1.9 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
0.1 | 1.1 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
0.1 | 0.9 | GO:0042582 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
0.1 | 2.5 | GO:0034707 | chloride channel complex(GO:0034707) |
0.1 | 0.4 | GO:0014802 | terminal cisterna(GO:0014802) |
0.1 | 0.6 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
0.1 | 0.3 | GO:0098888 | extrinsic component of presynaptic membrane(GO:0098888) |
0.1 | 3.5 | GO:0044295 | axonal growth cone(GO:0044295) |
0.1 | 1.2 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
0.1 | 0.7 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
0.1 | 4.8 | GO:0043198 | dendritic shaft(GO:0043198) |
0.1 | 1.2 | GO:0043194 | axon initial segment(GO:0043194) |
0.1 | 9.8 | GO:0014069 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
0.1 | 10.3 | GO:0030427 | site of polarized growth(GO:0030427) |
0.0 | 0.3 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
0.0 | 1.5 | GO:0035371 | microtubule plus-end(GO:0035371) |
0.0 | 10.6 | GO:0045211 | postsynaptic membrane(GO:0045211) |
0.0 | 0.4 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
0.0 | 0.3 | GO:0090571 | RNA polymerase II transcription repressor complex(GO:0090571) |
0.0 | 0.4 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
0.0 | 0.3 | GO:0005869 | dynactin complex(GO:0005869) |
0.0 | 0.6 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
0.0 | 0.2 | GO:0032433 | filopodium tip(GO:0032433) |
0.0 | 0.7 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
0.0 | 0.4 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
0.0 | 2.2 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
0.0 | 1.1 | GO:0016235 | aggresome(GO:0016235) |
0.0 | 0.8 | GO:0071339 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
0.0 | 1.4 | GO:0043195 | terminal bouton(GO:0043195) |
0.0 | 1.1 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
0.0 | 0.2 | GO:0032426 | stereocilium tip(GO:0032426) |
0.0 | 1.0 | GO:0035097 | histone methyltransferase complex(GO:0035097) |
0.0 | 2.9 | GO:0034399 | nuclear periphery(GO:0034399) |
0.0 | 0.4 | GO:0005865 | striated muscle thin filament(GO:0005865) |
0.0 | 0.1 | GO:0070876 | SOSS complex(GO:0070876) |
0.0 | 0.1 | GO:0097058 | CRLF-CLCF1 complex(GO:0097058) |
0.0 | 2.0 | GO:0036064 | ciliary basal body(GO:0036064) |
0.0 | 0.2 | GO:0017119 | Golgi transport complex(GO:0017119) |
0.0 | 3.0 | GO:0005802 | trans-Golgi network(GO:0005802) |
0.0 | 0.7 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
0.0 | 0.3 | GO:0000795 | synaptonemal complex(GO:0000795) |
0.0 | 0.7 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
0.0 | 1.0 | GO:0042641 | actomyosin(GO:0042641) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 2.5 | GO:0016934 | extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934) |
0.6 | 4.5 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
0.5 | 2.0 | GO:0047275 | glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275) |
0.5 | 3.4 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
0.5 | 1.8 | GO:0016909 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
0.4 | 2.4 | GO:0022851 | GABA-gated chloride ion channel activity(GO:0022851) |
0.4 | 1.9 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
0.3 | 0.9 | GO:0004517 | nitric-oxide synthase activity(GO:0004517) |
0.3 | 1.4 | GO:0030144 | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144) |
0.3 | 3.7 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
0.3 | 3.1 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
0.2 | 0.7 | GO:1990450 | linear polyubiquitin binding(GO:1990450) |
0.2 | 1.8 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
0.2 | 4.2 | GO:0030275 | LRR domain binding(GO:0030275) |
0.2 | 1.6 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
0.2 | 0.6 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
0.2 | 1.4 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
0.2 | 1.8 | GO:0030274 | LIM domain binding(GO:0030274) |
0.2 | 1.3 | GO:0001609 | G-protein coupled adenosine receptor activity(GO:0001609) heterotrimeric G-protein binding(GO:0032795) |
0.2 | 0.7 | GO:0001847 | opsonin receptor activity(GO:0001847) |
0.2 | 0.5 | GO:0005006 | epidermal growth factor-activated receptor activity(GO:0005006) |
0.2 | 0.7 | GO:0031800 | type 3 metabotropic glutamate receptor binding(GO:0031800) |
0.2 | 0.7 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
0.2 | 2.2 | GO:0045499 | chemorepellent activity(GO:0045499) |
0.1 | 1.0 | GO:0004118 | cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) |
0.1 | 1.3 | GO:0061676 | importin-alpha family protein binding(GO:0061676) |
0.1 | 6.4 | GO:0046875 | ephrin receptor binding(GO:0046875) |
0.1 | 0.4 | GO:0005219 | ryanodine-sensitive calcium-release channel activity(GO:0005219) |
0.1 | 0.6 | GO:0003835 | beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835) |
0.1 | 0.8 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
0.1 | 1.9 | GO:0042043 | neurexin family protein binding(GO:0042043) |
0.1 | 1.1 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
0.1 | 1.8 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
0.1 | 0.6 | GO:0019841 | retinol binding(GO:0019841) |
0.1 | 0.7 | GO:0035662 | Toll-like receptor 4 binding(GO:0035662) |
0.1 | 1.1 | GO:0070008 | serine-type exopeptidase activity(GO:0070008) |
0.1 | 2.9 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
0.1 | 1.3 | GO:0030955 | potassium ion binding(GO:0030955) |
0.1 | 0.8 | GO:0043995 | histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972) |
0.1 | 0.3 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
0.1 | 0.8 | GO:0008556 | sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556) |
0.1 | 1.4 | GO:0008188 | neuropeptide receptor activity(GO:0008188) |
0.1 | 0.7 | GO:0070700 | BMP receptor binding(GO:0070700) |
0.1 | 2.0 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
0.1 | 1.3 | GO:0030506 | ankyrin binding(GO:0030506) |
0.1 | 0.8 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
0.1 | 1.4 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
0.0 | 0.7 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
0.0 | 4.2 | GO:0035254 | glutamate receptor binding(GO:0035254) |
0.0 | 1.4 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
0.0 | 0.2 | GO:0072542 | protein phosphatase activator activity(GO:0072542) |
0.0 | 4.0 | GO:0008081 | phosphoric diester hydrolase activity(GO:0008081) |
0.0 | 1.9 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
0.0 | 0.2 | GO:0031702 | angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702) |
0.0 | 0.2 | GO:0001032 | RNA polymerase III type 3 promoter DNA binding(GO:0001032) |
0.0 | 0.4 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
0.0 | 0.4 | GO:0050692 | DBD domain binding(GO:0050692) |
0.0 | 0.7 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
0.0 | 1.7 | GO:0036002 | pre-mRNA binding(GO:0036002) |
0.0 | 0.4 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
0.0 | 4.9 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
0.0 | 1.1 | GO:0005262 | calcium channel activity(GO:0005262) |
0.0 | 1.2 | GO:0043621 | protein self-association(GO:0043621) |
0.0 | 0.2 | GO:0038191 | neuropilin binding(GO:0038191) |
0.0 | 0.3 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
0.0 | 0.3 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
0.0 | 2.0 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
0.0 | 0.3 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
0.0 | 0.0 | GO:0030249 | cyclase regulator activity(GO:0010851) guanylate cyclase regulator activity(GO:0030249) |
0.0 | 0.3 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
0.0 | 0.3 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
0.0 | 0.2 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
0.0 | 0.3 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
0.0 | 3.3 | GO:0004857 | enzyme inhibitor activity(GO:0004857) |
0.0 | 0.2 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
0.0 | 0.3 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
0.0 | 0.3 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.0 | 5.7 | GO:0005509 | calcium ion binding(GO:0005509) |
0.0 | 2.1 | GO:0004386 | helicase activity(GO:0004386) |
0.0 | 0.1 | GO:0005522 | profilin binding(GO:0005522) |
0.0 | 2.4 | GO:0035091 | phosphatidylinositol binding(GO:0035091) |
0.0 | 1.7 | GO:0005516 | calmodulin binding(GO:0005516) |
0.0 | 0.0 | GO:0000099 | sulfur amino acid transmembrane transporter activity(GO:0000099) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 5.1 | PID_EPHA_FWDPATHWAY | EPHA forward signaling |
0.1 | 3.7 | PID_ARF6_DOWNSTREAM_PATHWAY | Arf6 downstream pathway |
0.1 | 1.9 | PID_NCADHERIN_PATHWAY | N-cadherin signaling events |
0.1 | 3.6 | ST_ADRENERGIC | Adrenergic Pathway |
0.1 | 4.2 | PID_FGF_PATHWAY | FGF signaling pathway |
0.1 | 4.1 | PID_LKB1_PATHWAY | LKB1 signaling events |
0.1 | 0.5 | PID_ERBB_NETWORK_PATHWAY | ErbB receptor signaling network |
0.0 | 1.8 | PID_CD8_TCR_PATHWAY | TCR signaling in naïve CD8+ T cells |
0.0 | 2.6 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
0.0 | 1.2 | PID_P38_ALPHA_BETA_PATHWAY | Regulation of p38-alpha and p38-beta |
0.0 | 2.0 | PID_TRKR_PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
0.0 | 0.7 | PID_RAS_PATHWAY | Regulation of Ras family activation |
0.0 | 0.8 | PID_SHP2_PATHWAY | SHP2 signaling |
0.0 | 0.4 | ST_MYOCYTE_AD_PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
0.0 | 0.2 | PID_THROMBIN_PAR4_PATHWAY | PAR4-mediated thrombin signaling events |
0.0 | 0.4 | PID_GMCSF_PATHWAY | GMCSF-mediated signaling events |
0.0 | 1.3 | PID_PLK1_PATHWAY | PLK1 signaling events |
0.0 | 0.2 | SA_B_CELL_RECEPTOR_COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
0.0 | 1.1 | PID_ERA_GENOMIC_PATHWAY | Validated nuclear estrogen receptor alpha network |
0.0 | 0.9 | PID_CDC42_PATHWAY | CDC42 signaling events |
0.0 | 0.3 | PID_RET_PATHWAY | Signaling events regulated by Ret tyrosine kinase |
0.0 | 0.4 | PID_PS1_PATHWAY | Presenilin action in Notch and Wnt signaling |
0.0 | 0.6 | PID_TGFBR_PATHWAY | TGF-beta receptor signaling |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 8.0 | REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT | Genes involved in Ligand-gated ion channel transport |
0.3 | 7.3 | REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
0.2 | 4.0 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION | Genes involved in N-Glycan antennae elongation |
0.1 | 1.1 | REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
0.1 | 2.6 | REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 | Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
0.1 | 5.3 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
0.1 | 2.0 | REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP | Genes involved in Destabilization of mRNA by Tristetraprolin (TTP) |
0.1 | 1.8 | REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
0.1 | 5.1 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | Genes involved in NRAGE signals death through JNK |
0.1 | 2.3 | REACTOME_DARPP_32_EVENTS | Genes involved in DARPP-32 events |
0.1 | 1.8 | REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE | Genes involved in Nitric oxide stimulates guanylate cyclase |
0.1 | 1.1 | REACTOME_DOWNSTREAM_TCR_SIGNALING | Genes involved in Downstream TCR signaling |
0.0 | 0.3 | REACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR | Genes involved in Prostacyclin signalling through prostacyclin receptor |
0.0 | 1.3 | REACTOME_NEPHRIN_INTERACTIONS | Genes involved in Nephrin interactions |
0.0 | 1.5 | REACTOME_EGFR_DOWNREGULATION | Genes involved in EGFR downregulation |
0.0 | 0.5 | REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS | Genes involved in Nucleotide-like (purinergic) receptors |
0.0 | 0.3 | REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION | Genes involved in FGFR4 ligand binding and activation |
0.0 | 1.3 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
0.0 | 0.3 | REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
0.0 | 0.2 | REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR | Genes involved in Thromboxane signalling through TP receptor |
0.0 | 0.5 | REACTOME_GRB2_EVENTS_IN_ERBB2_SIGNALING | Genes involved in GRB2 events in ERBB2 signaling |
0.0 | 0.3 | REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
0.0 | 0.8 | REACTOME_ION_CHANNEL_TRANSPORT | Genes involved in Ion channel transport |
0.0 | 0.4 | REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
0.0 | 0.4 | REACTOME_STRIATED_MUSCLE_CONTRACTION | Genes involved in Striated Muscle Contraction |
0.0 | 1.4 | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
0.0 | 0.7 | REACTOME_POTASSIUM_CHANNELS | Genes involved in Potassium Channels |
0.0 | 0.1 | REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES | Genes involved in Generation of second messenger molecules |
0.0 | 0.2 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |