Motif ID: Nr5a2

Z-value: 0.639


Transcription factors associated with Nr5a2:

Gene SymbolEntrez IDGene Name
Nr5a2 ENSMUSG00000026398.8 Nr5a2



Activity profile for motif Nr5a2.

activity profile for motif Nr5a2


Sorted Z-values histogram for motif Nr5a2

Sorted Z-values for motif Nr5a2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr5a2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_+_21722057 2.222 ENSMUST00000110476.3
Hist1h2bm
histone cluster 1, H2bm
chr13_-_56296551 1.494 ENSMUST00000021970.9
Cxcl14
chemokine (C-X-C motif) ligand 14
chr11_-_4704334 1.489 ENSMUST00000058407.5
Uqcr10
ubiquinol-cytochrome c reductase, complex III subunit X
chr7_-_4522427 1.448 ENSMUST00000098859.3
Tnni3
troponin I, cardiac 3
chr7_+_100493795 1.325 ENSMUST00000129324.1
Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr15_-_79804717 1.259 ENSMUST00000023057.8
Nptxr
neuronal pentraxin receptor
chr9_-_119578981 1.214 ENSMUST00000117911.1
ENSMUST00000120420.1
Scn5a

sodium channel, voltage-gated, type V, alpha

chr2_-_73911323 1.208 ENSMUST00000111996.1
ENSMUST00000018914.2
Atp5g3

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)

chr7_+_100494044 1.202 ENSMUST00000153287.1
Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr12_-_111672290 1.103 ENSMUST00000001304.7
Ckb
creatine kinase, brain
chr13_+_21787461 1.052 ENSMUST00000110473.2
ENSMUST00000102982.1
Hist1h2bp

histone cluster 1, H2bp

chr13_-_21787218 1.037 ENSMUST00000091751.2
Hist1h2an
histone cluster 1, H2an
chr18_+_6332587 1.011 ENSMUST00000097682.2
Rpl27-ps3
ribosomal protein L27, pseudogene 3
chr2_-_166155624 0.991 ENSMUST00000109249.2
Sulf2
sulfatase 2
chr1_+_131970589 0.985 ENSMUST00000027695.6
Slc45a3
solute carrier family 45, member 3
chr9_-_96437434 0.935 ENSMUST00000070500.2
BC043934
cDNA sequence BC043934
chr16_-_91931643 0.933 ENSMUST00000023677.3
Atp5o
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
chr3_+_14886426 0.920 ENSMUST00000029078.7
Car2
carbonic anhydrase 2
chr7_+_46847128 0.917 ENSMUST00000005051.4
Ldha
lactate dehydrogenase A
chr14_+_75455957 0.883 ENSMUST00000164848.1
Siah3
seven in absentia homolog 3 (Drosophila)
chr1_+_45981548 0.844 ENSMUST00000085632.2
Rpl23a-ps1
ribosomal protein 23A, pseudogene 1
chr1_+_36691487 0.843 ENSMUST00000081180.4
Cox5b
cytochrome c oxidase subunit Vb
chr15_-_35938009 0.828 ENSMUST00000156915.1
Cox6c
cytochrome c oxidase subunit VIc
chr13_+_22043189 0.825 ENSMUST00000110452.1
Hist1h2bj
histone cluster 1, H2bj
chr17_+_43952999 0.818 ENSMUST00000177857.1
Rcan2
regulator of calcineurin 2
chr11_+_120484613 0.818 ENSMUST00000043627.7
Mrpl12
mitochondrial ribosomal protein L12
chr18_+_77185815 0.812 ENSMUST00000079618.4
St8sia5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr9_-_77347816 0.805 ENSMUST00000184138.1
ENSMUST00000184006.1
ENSMUST00000185144.1
ENSMUST00000034910.9
Mlip



muscular LMNA-interacting protein



chr10_+_94198955 0.797 ENSMUST00000020209.9
ENSMUST00000179990.1
Ndufa12

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12

chrX_-_141874870 0.795 ENSMUST00000182079.1
Gm15294
predicted gene 15294
chr13_-_21716143 0.788 ENSMUST00000091756.1
Hist1h2bl
histone cluster 1, H2bl
chr8_-_70523085 0.779 ENSMUST00000137610.1
ENSMUST00000121623.1
ENSMUST00000093456.5
ENSMUST00000118850.1
Kxd1



KxDL motif containing 1



chr16_+_18776839 0.771 ENSMUST00000043577.1
Cldn5
claudin 5
chr13_-_21753851 0.771 ENSMUST00000074752.2
Hist1h2ak
histone cluster 1, H2ak
chr12_-_110978981 0.764 ENSMUST00000135131.1
ENSMUST00000043459.6
ENSMUST00000128353.1
Ankrd9


ankyrin repeat domain 9


chr13_-_22042949 0.759 ENSMUST00000091741.4
Hist1h2ag
histone cluster 1, H2ag
chrM_+_8600 0.757 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chr11_+_6415443 0.752 ENSMUST00000132846.1
Ppia
peptidylprolyl isomerase A
chr14_-_77252327 0.752 ENSMUST00000099431.4
Gm10132
predicted gene 10132
chr2_+_121295437 0.751 ENSMUST00000110639.1
Map1a
microtubule-associated protein 1 A
chrX_-_72656135 0.751 ENSMUST00000055966.6
Gabra3
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3
chr2_+_121357714 0.744 ENSMUST00000125812.1
ENSMUST00000078222.2
ENSMUST00000125221.1
ENSMUST00000150271.1
Ckmt1



creatine kinase, mitochondrial 1, ubiquitous



chr6_-_76497631 0.737 ENSMUST00000097218.5
Gm9008
predicted pseudogene 9008
chr7_-_116237767 0.734 ENSMUST00000182834.1
Plekha7
pleckstrin homology domain containing, family A member 7
chr14_+_122181694 0.724 ENSMUST00000026625.5
Clybl
citrate lyase beta like
chr15_+_85116829 0.718 ENSMUST00000105085.1
Gm10923
predicted gene 10923
chr15_-_35938186 0.708 ENSMUST00000014457.8
Cox6c
cytochrome c oxidase subunit VIc
chr6_-_135168162 0.699 ENSMUST00000045855.7
Hebp1
heme binding protein 1
chr7_-_98145472 0.696 ENSMUST00000098281.2
Omp
olfactory marker protein
chr13_-_21501418 0.693 ENSMUST00000044043.2
Gm11273
predicted gene 11273
chr8_+_94152607 0.691 ENSMUST00000034211.8
Mt3
metallothionein 3
chr15_+_85510812 0.676 ENSMUST00000079690.2
Gm4825
predicted pseudogene 4825
chr1_-_52091066 0.676 ENSMUST00000105087.1
Gm3940
predicted gene 3940
chr12_+_12911986 0.676 ENSMUST00000085720.1
Rpl36-ps3
ribosomal protein L36, pseudogene 3
chr10_+_14523062 0.674 ENSMUST00000096020.5
Gm10335
predicted gene 10335
chr15_+_34238026 0.673 ENSMUST00000022867.3
Laptm4b
lysosomal-associated protein transmembrane 4B
chr12_-_34291092 0.667 ENSMUST00000166546.2
Gm18025
predicted gene, 18025
chr3_+_94377432 0.663 ENSMUST00000107292.1
Rorc
RAR-related orphan receptor gamma
chr8_+_71464910 0.663 ENSMUST00000048914.6
Mrpl34
mitochondrial ribosomal protein L34
chr8_-_120668003 0.657 ENSMUST00000181334.1
Emc8
ER membrane protein complex subunit 8
chr8_+_120668308 0.655 ENSMUST00000181795.1
Cox4i1
cytochrome c oxidase subunit IV isoform 1
chr14_+_34170640 0.653 ENSMUST00000104925.3
Rpl23a-ps3
ribosomal protein L23A, pseudogene 3
chr11_-_3504766 0.649 ENSMUST00000044507.5
Inpp5j
inositol polyphosphate 5-phosphatase J
chr19_-_60874526 0.645 ENSMUST00000025961.6
Prdx3
peroxiredoxin 3
chr4_-_36136463 0.636 ENSMUST00000098151.2
Lingo2
leucine rich repeat and Ig domain containing 2
chr7_+_78783119 0.633 ENSMUST00000032840.4
Mrps11
mitochondrial ribosomal protein S11
chr5_-_137613759 0.631 ENSMUST00000155251.1
ENSMUST00000124693.1
Pcolce

procollagen C-endopeptidase enhancer protein

chr8_+_84970068 0.630 ENSMUST00000164807.1
Prdx2
peroxiredoxin 2
chr11_-_53430779 0.618 ENSMUST00000061326.4
ENSMUST00000109021.3
Uqcrq

ubiquinol-cytochrome c reductase, complex III subunit VII

chr8_+_120668222 0.618 ENSMUST00000034276.6
ENSMUST00000181586.1
Cox4i1

cytochrome c oxidase subunit IV isoform 1

chr3_+_146500071 0.616 ENSMUST00000119130.1
Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr4_+_63558748 0.615 ENSMUST00000077709.4
6330416G13Rik
RIKEN cDNA 6330416G13 gene
chr9_+_109832998 0.611 ENSMUST00000119376.1
ENSMUST00000122343.1
Nme6

NME/NM23 nucleoside diphosphate kinase 6

chr1_-_51941261 0.606 ENSMUST00000097103.3
Gm8420
predicted gene 8420
chrX_+_71556874 0.598 ENSMUST00000123100.1
Hmgb3
high mobility group box 3
chr10_-_80855187 0.590 ENSMUST00000035775.8
Lsm7
LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr4_-_45108038 0.586 ENSMUST00000107809.2
ENSMUST00000107808.2
ENSMUST00000107807.1
ENSMUST00000107810.2
Tomm5



translocase of outer mitochondrial membrane 5 homolog (yeast)



chr15_+_76343504 0.584 ENSMUST00000023210.6
Cyc1
cytochrome c-1
chr14_+_25694170 0.579 ENSMUST00000022419.6
Ppif
peptidylprolyl isomerase F (cyclophilin F)
chr9_-_77347889 0.573 ENSMUST00000185039.1
Mlip
muscular LMNA-interacting protein
chr4_-_139131058 0.571 ENSMUST00000143971.1
Minos1
mitochondrial inner membrane organizing system 1
chr4_+_140961203 0.566 ENSMUST00000010007.8
Sdhb
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
chr9_-_70141484 0.556 ENSMUST00000034749.8
Fam81a
family with sequence similarity 81, member A
chr2_-_131160006 0.555 ENSMUST00000103188.3
ENSMUST00000133602.1
ENSMUST00000028800.5
1700037H04Rik


RIKEN cDNA 1700037H04 gene


chr13_-_102958084 0.554 ENSMUST00000099202.3
ENSMUST00000172264.1
Mast4

microtubule associated serine/threonine kinase family member 4

chr9_+_109832749 0.554 ENSMUST00000147777.1
ENSMUST00000035053.5
ENSMUST00000133483.1
Nme6


NME/NM23 nucleoside diphosphate kinase 6


chr9_-_77347787 0.552 ENSMUST00000184848.1
ENSMUST00000184415.1
Mlip

muscular LMNA-interacting protein

chr3_+_94377505 0.549 ENSMUST00000098877.2
Rorc
RAR-related orphan receptor gamma
chr2_+_121358591 0.545 ENSMUST00000000317.6
ENSMUST00000129130.1
Ckmt1

creatine kinase, mitochondrial 1, ubiquitous

chrX_+_142825698 0.539 ENSMUST00000112888.1
Tmem164
transmembrane protein 164
chr1_+_92831614 0.539 ENSMUST00000045970.6
Gpc1
glypican 1
chr12_+_105032638 0.538 ENSMUST00000021522.3
Glrx5
glutaredoxin 5 homolog (S. cerevisiae)
chr9_-_106891401 0.534 ENSMUST00000069036.7
Manf
mesencephalic astrocyte-derived neurotrophic factor
chr10_+_128083273 0.534 ENSMUST00000026459.5
Atp5b
ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit
chr19_-_47090610 0.531 ENSMUST00000096014.3
Usmg5
upregulated during skeletal muscle growth 5
chr3_-_89213840 0.530 ENSMUST00000173477.1
ENSMUST00000119222.1
Mtx1

metaxin 1

chr14_+_32321987 0.529 ENSMUST00000022480.7
Ogdhl
oxoglutarate dehydrogenase-like
chr6_+_91156665 0.521 ENSMUST00000041736.4
Hdac11
histone deacetylase 11
chr18_+_77773956 0.519 ENSMUST00000114748.1
Atp5a1
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1
chr2_-_26604267 0.518 ENSMUST00000028286.5
Agpat2
1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
chr11_+_9118070 0.516 ENSMUST00000020677.1
ENSMUST00000101525.2
ENSMUST00000170444.1
Upp1


uridine phosphorylase 1


chr7_-_81706905 0.508 ENSMUST00000026922.7
Homer2
homer homolog 2 (Drosophila)
chr17_-_25868727 0.507 ENSMUST00000026828.5
Fam195a
family with sequence similarity 195, member A
chr18_+_37955685 0.505 ENSMUST00000169498.2
Rell2
RELT-like 2
chr8_-_120668058 0.496 ENSMUST00000181950.1
ENSMUST00000181333.1
Emc8
Gm27021
ER membrane protein complex subunit 8
predicted gene, 27021
chr11_+_76407143 0.494 ENSMUST00000021203.6
ENSMUST00000152183.1
Timm22

translocase of inner mitochondrial membrane 22

chr9_-_44920698 0.490 ENSMUST00000043675.7
Atp5l
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit g
chr11_+_58948890 0.489 ENSMUST00000078267.3
Hist3h2ba
histone cluster 3, H2ba
chr11_+_98741805 0.489 ENSMUST00000064187.5
Thra
thyroid hormone receptor alpha
chr11_-_59839828 0.487 ENSMUST00000019517.3
Cops3
COP9 (constitutive photomorphogenic) homolog, subunit 3 (Arabidopsis thaliana)
chr4_+_123233556 0.475 ENSMUST00000040821.4
Heyl
hairy/enhancer-of-split related with YRPW motif-like
chr7_-_142576492 0.475 ENSMUST00000140716.1
H19
H19 fetal liver mRNA
chr7_+_79500018 0.466 ENSMUST00000182495.1
ENSMUST00000183043.1
AI854517

expressed sequence AI854517

chr7_+_4740111 0.464 ENSMUST00000098853.2
Suv420h2
suppressor of variegation 4-20 homolog 2 (Drosophila)
chr12_-_111966954 0.463 ENSMUST00000021719.5
2010107E04Rik
RIKEN cDNA 2010107E04 gene
chr13_+_21716385 0.461 ENSMUST00000070124.3
Hist1h2ai
histone cluster 1, H2ai
chr7_+_4740178 0.459 ENSMUST00000108583.2
Suv420h2
suppressor of variegation 4-20 homolog 2 (Drosophila)
chr6_+_91156772 0.458 ENSMUST00000143621.1
Hdac11
histone deacetylase 11
chr6_+_83349446 0.456 ENSMUST00000136501.1
Bola3
bolA-like 3 (E. coli)
chr9_+_50603892 0.456 ENSMUST00000044051.4
Timm8b
translocase of inner mitochondrial membrane 8B
chr8_+_26977336 0.451 ENSMUST00000154256.1
ENSMUST00000127097.1
Zfp703

zinc finger protein 703

chr1_-_131097535 0.442 ENSMUST00000016672.4
Mapkapk2
MAP kinase-activated protein kinase 2
chr11_+_67586520 0.436 ENSMUST00000108682.2
Gas7
growth arrest specific 7
chr13_+_98354234 0.436 ENSMUST00000105098.3
Foxd1
forkhead box D1
chr5_+_118065360 0.435 ENSMUST00000031305.3
Gm9754
predicted gene 9754
chr5_-_24445166 0.433 ENSMUST00000115043.1
ENSMUST00000115041.1
Fastk

Fas-activated serine/threonine kinase

chr2_-_157566319 0.431 ENSMUST00000109528.2
ENSMUST00000088494.2
Blcap

bladder cancer associated protein homolog (human)

chr11_+_67586675 0.431 ENSMUST00000108680.1
Gas7
growth arrest specific 7
chr8_-_13494479 0.428 ENSMUST00000033828.5
Gas6
growth arrest specific 6
chr11_+_9118507 0.421 ENSMUST00000164791.1
ENSMUST00000130522.1
Upp1

uridine phosphorylase 1

chr9_-_50603792 0.421 ENSMUST00000000175.4
Sdhd
succinate dehydrogenase complex, subunit D, integral membrane protein
chr2_+_30416096 0.407 ENSMUST00000113601.3
ENSMUST00000113603.3
Ppp2r4

protein phosphatase 2A, regulatory subunit B (PR 53)

chr15_-_52478228 0.405 ENSMUST00000081993.1
Gm10020
predicted pseudogene 10020
chr1_-_171222508 0.402 ENSMUST00000005817.2
Tomm40l
translocase of outer mitochondrial membrane 40 homolog-like (yeast)
chr3_-_96220880 0.397 ENSMUST00000090782.3
Hist2h2ac
histone cluster 2, H2ac
chr19_-_3912711 0.386 ENSMUST00000075092.6
Ndufs8
NADH dehydrogenase (ubiquinone) Fe-S protein 8
chr14_-_103844173 0.385 ENSMUST00000022718.3
Ednrb
endothelin receptor type B
chr5_-_24445254 0.379 ENSMUST00000030800.6
Fastk
Fas-activated serine/threonine kinase
chr19_-_7217549 0.375 ENSMUST00000039758.4
Cox8a
cytochrome c oxidase subunit VIIIa
chr9_+_59656368 0.374 ENSMUST00000034834.9
ENSMUST00000163694.2
Pkm

pyruvate kinase, muscle

chr11_-_59839745 0.369 ENSMUST00000141415.1
Cops3
COP9 (constitutive photomorphogenic) homolog, subunit 3 (Arabidopsis thaliana)
chr6_+_91157373 0.369 ENSMUST00000155007.1
Hdac11
histone deacetylase 11
chr7_-_19665005 0.368 ENSMUST00000055242.9
Clptm1
cleft lip and palate associated transmembrane protein 1
chr15_-_79285502 0.366 ENSMUST00000165408.1
Baiap2l2
BAI1-associated protein 2-like 2
chr3_+_32736990 0.366 ENSMUST00000127477.1
ENSMUST00000121778.1
ENSMUST00000154257.1
Ndufb5


NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5


chr5_+_34336928 0.365 ENSMUST00000182047.1
Rnf4
ring finger protein 4
chr2_+_30416031 0.365 ENSMUST00000042055.3
Ppp2r4
protein phosphatase 2A, regulatory subunit B (PR 53)
chr4_+_128993224 0.364 ENSMUST00000030583.6
ENSMUST00000102604.4
Ak2

adenylate kinase 2

chr9_+_107296843 0.360 ENSMUST00000167072.1
Cish
cytokine inducible SH2-containing protein
chr15_+_3270767 0.360 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
Sepp1



selenoprotein P, plasma, 1



chr19_-_46327121 0.359 ENSMUST00000041391.4
ENSMUST00000096029.5
Psd

pleckstrin and Sec7 domain containing

chr19_-_6980420 0.354 ENSMUST00000070878.8
ENSMUST00000177752.1
Fkbp2

FK506 binding protein 2

chr17_+_47737030 0.352 ENSMUST00000086932.3
Tfeb
transcription factor EB
chr7_-_141429351 0.347 ENSMUST00000164387.1
ENSMUST00000137488.1
ENSMUST00000084436.3
Cend1


cell cycle exit and neuronal differentiation 1


chr7_-_100583072 0.345 ENSMUST00000152876.1
ENSMUST00000150042.1
Mrpl48

mitochondrial ribosomal protein L48

chr7_-_141429433 0.345 ENSMUST00000124444.1
Cend1
cell cycle exit and neuronal differentiation 1
chr15_+_84669565 0.345 ENSMUST00000171460.1
Prr5
proline rich 5 (renal)
chr9_-_106891870 0.343 ENSMUST00000160503.1
ENSMUST00000159620.2
ENSMUST00000160978.1
Manf


mesencephalic astrocyte-derived neurotrophic factor


chr2_+_118598209 0.339 ENSMUST00000038341.7
Bub1b
budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)
chr7_+_4740137 0.336 ENSMUST00000130215.1
ENSMUST00000108582.3
Suv420h2

suppressor of variegation 4-20 homolog 2 (Drosophila)

chr7_-_105482197 0.336 ENSMUST00000047040.2
Prkcdbp
protein kinase C, delta binding protein
chr5_+_34336289 0.331 ENSMUST00000182709.1
ENSMUST00000030992.6
Rnf4

ring finger protein 4

chr13_+_23746734 0.330 ENSMUST00000099703.2
Hist1h2bb
histone cluster 1, H2bb
chr7_-_4522794 0.328 ENSMUST00000140424.1
Tnni3
troponin I, cardiac 3
chr15_-_77928925 0.328 ENSMUST00000109748.2
ENSMUST00000109747.2
ENSMUST00000100486.5
ENSMUST00000005487.5
Txn2



thioredoxin 2



chr11_-_94677404 0.325 ENSMUST00000116349.2
Xylt2
xylosyltransferase II
chr1_-_171222435 0.323 ENSMUST00000147246.1
ENSMUST00000111326.1
ENSMUST00000138184.1
Tomm40l


translocase of outer mitochondrial membrane 40 homolog-like (yeast)


chr2_+_178141920 0.321 ENSMUST00000103066.3
Phactr3
phosphatase and actin regulator 3
chr7_-_105574324 0.320 ENSMUST00000081165.7
Apbb1
amyloid beta (A4) precursor protein-binding, family B, member 1
chr18_+_37955544 0.320 ENSMUST00000070709.2
ENSMUST00000177058.1
ENSMUST00000169360.2
ENSMUST00000163591.2
ENSMUST00000091932.5
Rell2




RELT-like 2




chr17_-_35916323 0.319 ENSMUST00000172642.1
ENSMUST00000174807.1
ENSMUST00000174349.1
ENSMUST00000025305.9
ENSMUST00000113782.3
Mrps18b




mitochondrial ribosomal protein S18B




chr19_-_5366285 0.318 ENSMUST00000170010.1
Banf1
barrier to autointegration factor 1
chr7_+_30308772 0.313 ENSMUST00000136887.1
Alkbh6
alkB, alkylation repair homolog 6 (E. coli)
chr11_-_102407315 0.311 ENSMUST00000149777.1
ENSMUST00000154001.1
Slc25a39

solute carrier family 25, member 39

chr15_+_74563738 0.310 ENSMUST00000170845.1
Bai1
brain-specific angiogenesis inhibitor 1
chr16_-_18248697 0.309 ENSMUST00000115645.3
Ranbp1
RAN binding protein 1
chr13_+_55445301 0.306 ENSMUST00000001115.8
ENSMUST00000099482.3
Grk6

G protein-coupled receptor kinase 6

chr5_+_129725063 0.305 ENSMUST00000086046.3
Gbas
glioblastoma amplified sequence
chr13_-_66905322 0.305 ENSMUST00000021993.4
Uqcrb
ubiquinol-cytochrome c reductase binding protein
chr9_+_123150941 0.304 ENSMUST00000026890.4
Clec3b
C-type lectin domain family 3, member b
chr19_-_6996025 0.303 ENSMUST00000041686.3
ENSMUST00000180765.1
Nudt22

nudix (nucleoside diphosphate linked moiety X)-type motif 22

chr7_-_110862944 0.303 ENSMUST00000033050.3
Lyve1
lymphatic vessel endothelial hyaluronan receptor 1
chr7_+_79500081 0.300 ENSMUST00000181511.2
ENSMUST00000182937.1
AI854517

expressed sequence AI854517

chr11_+_117199641 0.300 ENSMUST00000093907.4
Sept9
septin 9
chr7_-_37773555 0.299 ENSMUST00000176534.1
Zfp536
zinc finger protein 536
chr1_-_167393826 0.298 ENSMUST00000028005.2
Mgst3
microsomal glutathione S-transferase 3
chr8_+_70863127 0.298 ENSMUST00000050921.2
A230052G05Rik
RIKEN cDNA A230052G05 gene
chr8_+_84969824 0.297 ENSMUST00000125893.1
Prdx2
peroxiredoxin 2
chr15_-_98831498 0.294 ENSMUST00000168846.1
Prkag1
protein kinase, AMP-activated, gamma 1 non-catalytic subunit
chr17_+_24470393 0.291 ENSMUST00000053024.6
Pgp
phosphoglycolate phosphatase
chr2_-_26021532 0.291 ENSMUST00000136750.1
Ubac1
ubiquitin associated domain containing 1
chr2_+_140170641 0.287 ENSMUST00000044825.4
Ndufaf5
NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
chr8_-_85555261 0.287 ENSMUST00000034138.5
Dnaja2
DnaJ (Hsp40) homolog, subfamily A, member 2
chr8_+_84969767 0.283 ENSMUST00000109733.1
Prdx2
peroxiredoxin 2
chr2_-_26021679 0.279 ENSMUST00000036509.7
Ubac1
ubiquitin associated domain containing 1
chr5_+_24364804 0.276 ENSMUST00000030834.4
ENSMUST00000115090.1
Nos3

nitric oxide synthase 3, endothelial cell

chr15_+_23036449 0.276 ENSMUST00000164787.1
Cdh18
cadherin 18
chr5_-_137611372 0.275 ENSMUST00000054564.6
Pcolce
procollagen C-endopeptidase enhancer protein
chr4_-_155761042 0.275 ENSMUST00000030903.5
Atad3a
ATPase family, AAA domain containing 3A
chr2_+_131186942 0.274 ENSMUST00000028804.8
ENSMUST00000079857.8
Cdc25b

cell division cycle 25B


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.4 2.7 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.4 1.2 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) membrane depolarization during Purkinje myocyte cell action potential(GO:0086047)
0.4 2.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.3 1.0 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.3 0.9 GO:0046133 pyrimidine ribonucleoside catabolic process(GO:0046133)
0.3 0.9 GO:0035672 regulation of cellular pH reduction(GO:0032847) oligopeptide transmembrane transport(GO:0035672)
0.3 2.5 GO:1990845 adaptive thermogenesis(GO:1990845)
0.2 1.0 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.2 2.7 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.2 1.2 GO:0019244 lactate biosynthetic process from pyruvate(GO:0019244)
0.2 0.7 GO:0021933 radial glia guided migration of cerebellar granule cell(GO:0021933)
0.2 1.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 0.6 GO:0097212 lysosomal membrane organization(GO:0097212)
0.2 0.6 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.2 0.6 GO:0019043 establishment of viral latency(GO:0019043)
0.2 1.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.2 0.5 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.2 0.9 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.2 0.5 GO:0019401 alditol biosynthetic process(GO:0019401)
0.2 0.5 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.2 0.5 GO:2000823 regulation of androgen receptor activity(GO:2000823)
0.2 1.2 GO:0072615 interleukin-17 secretion(GO:0072615)
0.1 0.4 GO:0072076 nephrogenic mesenchyme development(GO:0072076)
0.1 0.4 GO:0003104 positive regulation of glomerular filtration(GO:0003104) negative regulation of protein import into nucleus, translocation(GO:0033159) regulation of oligodendrocyte apoptotic process(GO:1900141) negative regulation of oligodendrocyte apoptotic process(GO:1900142) positive regulation of dendritic cell chemotaxis(GO:2000510)
0.1 0.3 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.1 0.7 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.5 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.1 0.6 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.1 0.8 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1 0.4 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.1 0.3 GO:0006106 fumarate metabolic process(GO:0006106)
0.1 0.7 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 1.2 GO:0002536 respiratory burst involved in inflammatory response(GO:0002536) negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1 0.6 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.1 0.4 GO:0009814 defense response, incompatible interaction(GO:0009814)
0.1 0.2 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.1 0.7 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.1 0.3 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1 0.3 GO:0030210 heparin biosynthetic process(GO:0030210)
0.1 1.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 0.6 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.8 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.3 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.1 2.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 0.4 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.4 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.1 0.3 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 0.3 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.1 0.5 GO:0006172 ADP biosynthetic process(GO:0006172)
0.1 0.3 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 0.3 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.1 0.2 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
0.1 0.9 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 0.2 GO:1904719 excitatory chemical synaptic transmission(GO:0098976) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.1 0.2 GO:0071544 diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.1 0.5 GO:0009249 protein lipoylation(GO:0009249)
0.1 0.3 GO:2000195 negative regulation of female gonad development(GO:2000195)
0.1 0.4 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.1 0.2 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 0.2 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 0.6 GO:0006105 succinate metabolic process(GO:0006105)
0.1 0.9 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 0.2 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.1 0.3 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.1 0.3 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.9 GO:0000338 protein deneddylation(GO:0000338)
0.1 0.2 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.1 GO:1902732 positive regulation of chondrocyte proliferation(GO:1902732)
0.0 0.1 GO:0002447 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
0.0 1.8 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 0.5 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.5 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 0.3 GO:0034331 cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217)
0.0 0.5 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.0 5.1 GO:0006334 nucleosome assembly(GO:0006334)
0.0 1.7 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.3 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.2 GO:0097491 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.0 0.5 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.8 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.3 GO:0007144 female meiosis I(GO:0007144)
0.0 0.3 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.2 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.3 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 3.5 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.2 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.8 GO:0007614 short-term memory(GO:0007614)
0.0 0.5 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.0 0.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 1.6 GO:0009060 aerobic respiration(GO:0009060)
0.0 0.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.6 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.5 GO:0042775 mitochondrial ATP synthesis coupled electron transport(GO:0042775)
0.0 0.8 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 1.4 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 0.2 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 1.0 GO:0042168 heme metabolic process(GO:0042168)
0.0 0.2 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.1 GO:0061622 glycolytic process through glucose-1-phosphate(GO:0061622)
0.0 0.0 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.0 0.3 GO:0060484 male sex determination(GO:0030238) lung-associated mesenchyme development(GO:0060484)
0.0 0.3 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 0.4 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.1 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.8 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.1 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.4 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.0 0.3 GO:0042026 protein refolding(GO:0042026)
0.0 0.5 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.5 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.0 GO:0071649 regulation of chemokine (C-C motif) ligand 5 production(GO:0071649)
0.0 0.3 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.1 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.4 GO:2000398 regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.0 0.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211) long-chain fatty acid import(GO:0044539)
0.0 0.4 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.2 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.3 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.0 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.3 GO:0045116 protein neddylation(GO:0045116)
0.0 0.2 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.0 0.1 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.0 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:1990584 cardiac Troponin complex(GO:1990584)
0.3 3.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.2 0.9 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.2 2.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 0.6 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.2 2.6 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.2 1.6 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.2 1.5 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 1.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 0.6 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 5.5 GO:0000786 nucleosome(GO:0000786)
0.1 0.4 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.1 0.8 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 0.7 GO:0005915 zonula adherens(GO:0005915)
0.1 0.9 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 0.3 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.1 0.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.3 GO:0001652 granular component(GO:0001652)
0.1 0.6 GO:0046930 pore complex(GO:0046930)
0.0 0.3 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.1 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.5 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.4 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.8 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.8 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.1 GO:0072534 perineuronal net(GO:0072534)
0.0 2.2 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.2 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 1.7 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.4 GO:0071439 clathrin complex(GO:0071439)
0.0 0.4 GO:0005687 U4 snRNP(GO:0005687)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.3 GO:0031105 septin complex(GO:0031105)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.5 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0 1.0 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.1 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.0 0.2 GO:0042629 mast cell granule(GO:0042629)
0.0 0.3 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778) condensed chromosome outer kinetochore(GO:0000940)
0.0 5.9 GO:0043209 myelin sheath(GO:0043209)
0.0 0.3 GO:0031932 TORC2 complex(GO:0031932)
0.0 2.4 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.3 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.9 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.3 GO:1904115 axon cytoplasm(GO:1904115)
0.0 6.6 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.1 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.2 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 1.1 GO:0005604 basement membrane(GO:0005604)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.6 2.4 GO:0004111 creatine kinase activity(GO:0004111)
0.6 1.8 GO:0030172 troponin C binding(GO:0030172)
0.3 1.0 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.3 1.3 GO:0001847 opsonin receptor activity(GO:0001847)
0.3 0.9 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.3 1.2 GO:0008142 oxysterol binding(GO:0008142)
0.3 2.4 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.3 1.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.2 0.9 GO:0004064 arylesterase activity(GO:0004064)
0.2 3.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.2 0.6 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.2 4.7 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 1.0 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 1.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.2 1.9 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.2 0.5 GO:0070052 collagen V binding(GO:0070052)
0.2 0.5 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.2 0.5 GO:0035939 microsatellite binding(GO:0035939)
0.1 1.4 GO:0015266 protein channel activity(GO:0015266)
0.1 0.8 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.9 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.4 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 0.5 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.4 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.4 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.7 GO:0033142 progesterone receptor binding(GO:0033142)
0.1 0.3 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 0.3 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 0.3 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.2 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.1 0.2 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.1 0.3 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 0.5 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.2 GO:0031403 lithium ion binding(GO:0031403)
0.1 0.3 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.1 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 1.5 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 1.3 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 1.9 GO:0009055 electron carrier activity(GO:0009055)
0.1 0.4 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.7 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.6 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.2 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.0 0.4 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.2 GO:2001069 glycogen binding(GO:2001069)
0.0 0.3 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 2.6 GO:0005518 collagen binding(GO:0005518)
0.0 0.5 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.2 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 1.1 GO:0008009 chemokine activity(GO:0008009)
0.0 0.1 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.0 0.4 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.6 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.3 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.3 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.5 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.1 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.9 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 0.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 0.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.7 GO:0020037 heme binding(GO:0020037)
0.0 2.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.3 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.3 GO:0070182 DNA polymerase binding(GO:0070182)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.0 0.3 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.8 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.3 PID_ALK2_PATHWAY ALK2 signaling events
0.0 0.1 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 1.0 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.1 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 1.9 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.7 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.4 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.5 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.3 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.8 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.7 PID_INSULIN_PATHWAY Insulin Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 13.7 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_ Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.1 4.6 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.1 0.9 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.1 1.8 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.1 2.6 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.8 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism
0.0 0.4 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.3 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.5 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.0 1.0 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.9 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.3 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 2.0 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.4 REACTOME_P38MAPK_EVENTS Genes involved in p38MAPK events
0.0 0.3 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 1.5 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.2 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.6 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.2 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.5 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.6 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.5 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.1 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.0 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME_INHIBITION_OF_THE_PROTEOLYTIC_ACTIVITY_OF_APC_C_REQUIRED_FOR_THE_ONSET_OF_ANAPHASE_BY_MITOTIC_SPINDLE_CHECKPOINT_COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.3 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.5 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.3 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.1 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.2 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.2 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.2 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.3 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 0.2 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis