Motif ID: Nr0b1
Z-value: 0.610

Transcription factors associated with Nr0b1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Nr0b1 | ENSMUSG00000025056.4 | Nr0b1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Nr0b1 | mm10_v2_chrX_+_86191764_86191782 | -0.03 | 8.7e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 1.9 | GO:0072236 | DCT cell differentiation(GO:0072069) metanephric loop of Henle development(GO:0072236) metanephric DCT cell differentiation(GO:0072240) |
0.4 | 2.7 | GO:1903690 | negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
0.3 | 0.8 | GO:1904020 | regulation of G-protein coupled receptor internalization(GO:1904020) |
0.3 | 1.9 | GO:2001225 | cellular hypotonic response(GO:0071476) regulation of chloride transport(GO:2001225) |
0.2 | 0.8 | GO:0007223 | Wnt signaling pathway, calcium modulating pathway(GO:0007223) |
0.1 | 0.6 | GO:2001045 | closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045) |
0.1 | 0.6 | GO:0043973 | histone H3-K4 acetylation(GO:0043973) |
0.1 | 0.5 | GO:2000048 | negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048) |
0.1 | 1.6 | GO:0014842 | regulation of skeletal muscle satellite cell proliferation(GO:0014842) |
0.1 | 0.8 | GO:0072697 | protein localization to cell cortex(GO:0072697) |
0.1 | 0.4 | GO:0051661 | maintenance of centrosome location(GO:0051661) |
0.1 | 0.3 | GO:0007084 | mitotic nuclear envelope reassembly(GO:0007084) |
0.1 | 0.2 | GO:1902915 | negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915) |
0.1 | 0.3 | GO:2000383 | regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384) |
0.1 | 0.2 | GO:0036166 | phenotypic switching(GO:0036166) |
0.1 | 0.3 | GO:0008078 | zygotic determination of anterior/posterior axis, embryo(GO:0007354) mesodermal cell migration(GO:0008078) |
0.1 | 0.9 | GO:0071257 | cellular response to electrical stimulus(GO:0071257) |
0.1 | 0.4 | GO:0035878 | nail development(GO:0035878) |
0.1 | 0.9 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
0.0 | 0.7 | GO:0051639 | actin filament network formation(GO:0051639) |
0.0 | 0.3 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
0.0 | 0.1 | GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
0.0 | 1.1 | GO:0070207 | protein homotrimerization(GO:0070207) |
0.0 | 0.4 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
0.0 | 0.4 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
0.0 | 0.2 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
0.0 | 0.5 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
0.0 | 0.1 | GO:0000957 | mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960) |
0.0 | 0.7 | GO:0090036 | regulation of protein kinase C signaling(GO:0090036) |
0.0 | 0.3 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
0.0 | 0.1 | GO:0010643 | cell communication by chemical coupling(GO:0010643) negative regulation of locomotion involved in locomotory behavior(GO:0090327) |
0.0 | 0.2 | GO:0070561 | vitamin D receptor signaling pathway(GO:0070561) positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138) |
0.0 | 0.2 | GO:1904668 | positive regulation of ubiquitin protein ligase activity(GO:1904668) |
0.0 | 0.2 | GO:0090003 | regulation of Golgi to plasma membrane protein transport(GO:0042996) regulation of establishment of protein localization to plasma membrane(GO:0090003) |
0.0 | 0.5 | GO:0007520 | myoblast fusion(GO:0007520) |
0.0 | 1.7 | GO:0007050 | cell cycle arrest(GO:0007050) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 2.7 | GO:0045180 | basal cortex(GO:0045180) |
0.1 | 0.5 | GO:0002111 | BRCA2-BRAF35 complex(GO:0002111) |
0.1 | 0.5 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
0.1 | 0.4 | GO:0000235 | astral microtubule(GO:0000235) |
0.1 | 1.5 | GO:0008305 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
0.1 | 0.4 | GO:0046581 | intercellular canaliculus(GO:0046581) |
0.1 | 0.8 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
0.0 | 0.2 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
0.0 | 0.9 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
0.0 | 0.3 | GO:0045298 | tubulin complex(GO:0045298) |
0.0 | 0.3 | GO:0031209 | SCAR complex(GO:0031209) |
0.0 | 0.1 | GO:1902737 | dendritic filopodium(GO:1902737) |
0.0 | 0.7 | GO:0097440 | apical dendrite(GO:0097440) |
0.0 | 0.7 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
0.0 | 0.2 | GO:0005605 | basal lamina(GO:0005605) |
0.0 | 0.1 | GO:1990745 | EARP complex(GO:1990745) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 1.9 | GO:0004692 | cGMP-dependent protein kinase activity(GO:0004692) |
0.2 | 1.1 | GO:0098634 | protein binding involved in cell-matrix adhesion(GO:0098634) |
0.1 | 0.6 | GO:0072542 | protein phosphatase activator activity(GO:0072542) |
0.1 | 0.3 | GO:0042328 | heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328) |
0.1 | 0.6 | GO:0030274 | LIM domain binding(GO:0030274) |
0.1 | 1.9 | GO:0071837 | HMG box domain binding(GO:0071837) |
0.1 | 0.8 | GO:0004576 | oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
0.1 | 0.2 | GO:0008853 | exodeoxyribonuclease III activity(GO:0008853) |
0.1 | 0.3 | GO:0038132 | neuregulin binding(GO:0038132) |
0.1 | 1.4 | GO:0008432 | JUN kinase binding(GO:0008432) |
0.0 | 0.4 | GO:0071253 | connexin binding(GO:0071253) |
0.0 | 0.4 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
0.0 | 0.8 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
0.0 | 0.8 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.0 | 0.8 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
0.0 | 0.2 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
0.0 | 0.7 | GO:0003785 | actin monomer binding(GO:0003785) |
0.0 | 0.5 | GO:0000400 | four-way junction DNA binding(GO:0000400) |
0.0 | 0.2 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
0.0 | 0.4 | GO:0045505 | dynein intermediate chain binding(GO:0045505) |
0.0 | 0.2 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
0.0 | 0.2 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 0.4 | PID_INTEGRIN4_PATHWAY | Alpha6 beta4 integrin-ligand interactions |
0.0 | 0.9 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
0.0 | 1.1 | PID_ECADHERIN_STABILIZATION_PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
0.0 | 0.2 | PID_IL5_PATHWAY | IL5-mediated signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.9 | REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
0.1 | 0.4 | REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
0.0 | 0.9 | REACTOME_GAP_JUNCTION_DEGRADATION | Genes involved in Gap junction degradation |
0.0 | 0.9 | REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
0.0 | 0.2 | REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
0.0 | 0.2 | REACTOME_PROLACTIN_RECEPTOR_SIGNALING | Genes involved in Prolactin receptor signaling |
0.0 | 0.8 | REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |