Motif ID: Hsf4

Z-value: 0.820


Transcription factors associated with Hsf4:

Gene SymbolEntrez IDGene Name
Hsf4 ENSMUSG00000033249.4 Hsf4



Activity profile for motif Hsf4.

activity profile for motif Hsf4


Sorted Z-values histogram for motif Hsf4

Sorted Z-values for motif Hsf4



Network of associatons between targets according to the STRING database.



First level regulatory network of Hsf4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_194938821 2.614 ENSMUST00000016638.2
ENSMUST00000110815.2
Cd34

CD34 antigen

chr9_+_71215779 2.271 ENSMUST00000034723.5
Aldh1a2
aldehyde dehydrogenase family 1, subfamily A2
chr17_-_50094277 2.094 ENSMUST00000113195.1
Rftn1
raftlin lipid raft linker 1
chr12_-_72236692 1.879 ENSMUST00000021497.9
ENSMUST00000137990.1
Rtn1

reticulon 1

chr6_-_136941887 1.833 ENSMUST00000111891.1
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr4_-_136892867 1.820 ENSMUST00000046332.5
C1qc
complement component 1, q subcomponent, C chain
chr7_-_126949499 1.776 ENSMUST00000106339.1
ENSMUST00000052937.5
Asphd1

aspartate beta-hydroxylase domain containing 1

chr12_-_110696289 1.747 ENSMUST00000021698.6
Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr2_+_19344820 1.700 ENSMUST00000150514.1
ENSMUST00000136456.1
4930447M23Rik

RIKEN cDNA 4930447M23 gene

chr5_-_123749371 1.635 ENSMUST00000182955.1
ENSMUST00000182489.1
ENSMUST00000050827.7
Rsrc2


arginine/serine-rich coiled-coil 2


chr12_-_72408934 1.634 ENSMUST00000078505.7
Rtn1
reticulon 1
chr5_-_123749393 1.633 ENSMUST00000057795.5
ENSMUST00000111515.1
ENSMUST00000182309.1
Rsrc2


arginine/serine-rich coiled-coil 2


chr17_+_17316078 1.623 ENSMUST00000105311.3
Gm6712
predicted gene 6712
chr13_-_111490111 1.602 ENSMUST00000047627.7
Gpbp1
GC-rich promoter binding protein 1
chr4_+_40722461 1.495 ENSMUST00000030118.3
Dnaja1
DnaJ (Hsp40) homolog, subfamily A, member 1
chr6_-_136941494 1.460 ENSMUST00000111892.1
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr17_+_17831004 1.456 ENSMUST00000172097.2
4930546H06Rik
RIKEN cDNA 4930546H06 gene
chr9_+_13827708 1.448 ENSMUST00000059579.5
Fam76b
family with sequence similarity 76, member B
chr17_+_21707682 1.443 ENSMUST00000073312.6
Zfp760
zinc finger protein 760
chr2_-_113829069 1.410 ENSMUST00000024005.7
Scg5
secretogranin V
chr12_-_110696332 1.349 ENSMUST00000094361.4
Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr2_-_28466266 1.319 ENSMUST00000127683.1
ENSMUST00000086370.4
1700007K13Rik

RIKEN cDNA 1700007K13 gene

chr6_-_136941694 1.291 ENSMUST00000032344.5
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr16_+_23107413 1.288 ENSMUST00000023599.6
ENSMUST00000168891.1
Eif4a2

eukaryotic translation initiation factor 4A2

chr19_-_29812952 1.261 ENSMUST00000099525.3
Ranbp6
RAN binding protein 6
chr9_+_118040475 1.258 ENSMUST00000044454.5
Azi2
5-azacytidine induced gene 2
chr8_-_71537402 1.258 ENSMUST00000051672.7
Bst2
bone marrow stromal cell antigen 2
chr4_+_46039202 1.239 ENSMUST00000156200.1
Tmod1
tropomodulin 1
chrX_-_109013389 1.225 ENSMUST00000033597.8
Hmgn5
high-mobility group nucleosome binding domain 5
chr9_+_50752758 1.221 ENSMUST00000034562.7
Cryab
crystallin, alpha B
chr6_+_86527312 1.215 ENSMUST00000181928.1
1600020E01Rik
RIKEN cDNA 1600020E01 gene
chr13_-_111490028 1.181 ENSMUST00000091236.4
Gpbp1
GC-rich promoter binding protein 1
chr2_+_19344317 1.173 ENSMUST00000141289.1
4930447M23Rik
RIKEN cDNA 4930447M23 gene
chr11_+_116657106 1.172 ENSMUST00000116318.2
Gm11744
predicted gene 11744
chr10_-_62507737 1.170 ENSMUST00000020271.6
Srgn
serglycin
chr13_+_81657732 1.142 ENSMUST00000049055.6
Lysmd3
LysM, putative peptidoglycan-binding, domain containing 3
chr16_-_55934797 1.141 ENSMUST00000122280.1
ENSMUST00000121703.2
Cep97

centrosomal protein 97

chr16_+_23107754 1.136 ENSMUST00000077605.5
ENSMUST00000115341.3
Eif4a2

eukaryotic translation initiation factor 4A2

chr6_-_127769427 1.130 ENSMUST00000032500.8
Prmt8
protein arginine N-methyltransferase 8
chr2_+_157560078 1.096 ENSMUST00000153739.2
ENSMUST00000173595.1
ENSMUST00000109526.1
ENSMUST00000173839.1
ENSMUST00000173041.1
ENSMUST00000173793.1
ENSMUST00000172487.1
ENSMUST00000088484.5
Nnat







neuronatin







chr9_-_53706211 1.074 ENSMUST00000068449.3
Rab39
RAB39, member RAS oncogene family
chr5_+_29735940 1.069 ENSMUST00000114839.1
Dnajb6
DnaJ (Hsp40) homolog, subfamily B, member 6
chr3_+_30792876 1.066 ENSMUST00000029256.7
Sec62
SEC62 homolog (S. cerevisiae)
chr1_+_195017399 1.049 ENSMUST00000181273.1
A330023F24Rik
RIKEN cDNA A330023F24 gene
chr15_+_82252397 1.037 ENSMUST00000136948.1
1500009C09Rik
RIKEN cDNA 1500009C09 gene
chrX_+_73214333 1.026 ENSMUST00000156188.1
ENSMUST00000069077.3
ENSMUST00000069103.4
ENSMUST00000114506.1
ENSMUST00000081827.3
Xlr4b




X-linked lymphocyte-regulated 4B




chr17_+_34135182 1.026 ENSMUST00000042121.9
H2-DMa
histocompatibility 2, class II, locus DMa
chr4_+_127077374 1.023 ENSMUST00000046751.6
ENSMUST00000094713.3
Zmym6

zinc finger, MYM-type 6

chr10_+_68723723 0.987 ENSMUST00000080995.6
Tmem26
transmembrane protein 26
chr9_-_13827029 0.986 ENSMUST00000148086.1
ENSMUST00000034398.5
Cep57

centrosomal protein 57

chr4_-_40722307 0.937 ENSMUST00000181475.1
Gm6297
predicted gene 6297
chr11_+_69622024 0.934 ENSMUST00000108656.2
ENSMUST00000092969.1
Sat2

spermidine/spermine N1-acetyl transferase 2

chr16_-_55934845 0.932 ENSMUST00000121129.1
ENSMUST00000023270.7
Cep97

centrosomal protein 97

chr9_+_118040509 0.930 ENSMUST00000133580.1
Azi2
5-azacytidine induced gene 2
chrX_+_101640056 0.909 ENSMUST00000119299.1
ENSMUST00000044475.4
Ogt

O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)

chr5_-_112228934 0.887 ENSMUST00000181535.2
Miat
myocardial infarction associated transcript (non-protein coding)
chr11_+_21239279 0.881 ENSMUST00000006221.7
ENSMUST00000109578.1
Vps54

vacuolar protein sorting 54 (yeast)

chr6_+_51470339 0.861 ENSMUST00000094623.3
Cbx3
chromobox 3
chr7_-_110862944 0.850 ENSMUST00000033050.3
Lyve1
lymphatic vessel endothelial hyaluronan receptor 1
chr9_-_105495130 0.850 ENSMUST00000038118.7
Atp2c1
ATPase, Ca++-sequestering
chr6_-_54972603 0.844 ENSMUST00000060655.8
Nod1
nucleotide-binding oligomerization domain containing 1
chr14_+_18271122 0.840 ENSMUST00000132374.1
ENSMUST00000133460.1
Nkiras1

NFKB inhibitor interacting Ras-like protein 1

chr2_-_64975762 0.833 ENSMUST00000156765.1
Grb14
growth factor receptor bound protein 14
chr13_-_62607499 0.820 ENSMUST00000091563.4
6720489N17Rik
RIKEN cDNA 6720489N17 gene
chr2_+_121456963 0.814 ENSMUST00000126764.1
Hypk
huntingtin interacting protein K
chr5_+_66676098 0.785 ENSMUST00000031131.9
Uchl1
ubiquitin carboxy-terminal hydrolase L1
chr14_-_79390666 0.775 ENSMUST00000022597.7
Naa16
N(alpha)-acetyltransferase 16, NatA auxiliary subunit
chr11_+_21091291 0.764 ENSMUST00000093290.5
Peli1
pellino 1
chr16_-_22265950 0.760 ENSMUST00000161286.1
Tra2b
transformer 2 beta homolog (Drosophila)
chr12_-_110696248 0.758 ENSMUST00000124156.1
Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr13_-_97747399 0.756 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr9_-_103222063 0.756 ENSMUST00000170904.1
Trf
transferrin
chr2_+_130405256 0.754 ENSMUST00000110281.1
ENSMUST00000028898.3
1700020A23Rik

RIKEN cDNA 1700020A23 gene

chr19_-_28967794 0.752 ENSMUST00000162110.1
4430402I18Rik
RIKEN cDNA 4430402I18 gene
chr4_+_152178126 0.750 ENSMUST00000075363.3
Acot7
acyl-CoA thioesterase 7
chr6_-_59024470 0.747 ENSMUST00000089860.5
Fam13a
family with sequence similarity 13, member A
chr10_-_100589205 0.742 ENSMUST00000054471.8
4930430F08Rik
RIKEN cDNA 4930430F08 gene
chr3_-_107943390 0.742 ENSMUST00000106681.1
Gstm6
glutathione S-transferase, mu 6
chr2_+_172472512 0.738 ENSMUST00000029007.2
Fam209
family with sequence similarity 209
chr17_+_35262730 0.728 ENSMUST00000172785.1
H2-D1
histocompatibility 2, D region locus 1
chr2_-_160619971 0.716 ENSMUST00000109473.1
Gm14221
predicted gene 14221
chr7_+_119895836 0.699 ENSMUST00000106518.1
ENSMUST00000054440.3
Lyrm1

LYR motif containing 1

chr5_+_30281377 0.690 ENSMUST00000101448.3
Drc1
dynein regulatory complex subunit 1
chr11_+_17159263 0.687 ENSMUST00000102880.4
Ppp3r1
protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)
chr11_-_52000432 0.686 ENSMUST00000020657.6
Ube2b
ubiquitin-conjugating enzyme E2B
chr9_-_13826946 0.684 ENSMUST00000147115.1
Cep57
centrosomal protein 57
chr10_-_95416850 0.677 ENSMUST00000020215.9
Socs2
suppressor of cytokine signaling 2
chr9_+_88548013 0.674 ENSMUST00000162827.1
ENSMUST00000160652.1
ENSMUST00000162985.1
ENSMUST00000161232.1
ENSMUST00000161458.1
Zfp949




zinc finger protein 949




chr11_+_49609263 0.673 ENSMUST00000020617.2
Flt4
FMS-like tyrosine kinase 4
chrX_+_42149288 0.673 ENSMUST00000115073.2
ENSMUST00000115072.1
Stag2

stromal antigen 2

chr2_-_37359274 0.672 ENSMUST00000009174.8
Pdcl
phosducin-like
chr4_+_43875524 0.668 ENSMUST00000030198.6
Reck
reversion-inducing-cysteine-rich protein with kazal motifs
chr16_+_21794320 0.661 ENSMUST00000181780.1
ENSMUST00000181960.1
1300002E11Rik

RIKEN cDNA 1300002E11 gene

chr7_-_46179929 0.661 ENSMUST00000033123.6
Abcc8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr12_-_79172609 0.661 ENSMUST00000055262.6
Vti1b
vesicle transport through interaction with t-SNAREs 1B
chrX_-_73659724 0.656 ENSMUST00000114473.1
ENSMUST00000002087.7
Pnck

pregnancy upregulated non-ubiquitously expressed CaM kinase

chr5_-_103911196 0.652 ENSMUST00000031254.2
Klhl8
kelch-like 8
chr17_+_27029259 0.643 ENSMUST00000053683.6
Ggnbp1
gametogenetin binding protein 1
chr9_+_118040576 0.639 ENSMUST00000134433.1
Azi2
5-azacytidine induced gene 2
chr11_+_116843278 0.631 ENSMUST00000106370.3
Mettl23
methyltransferase like 23
chr7_+_92561141 0.625 ENSMUST00000032842.6
ENSMUST00000085017.4
Ccdc90b

coiled-coil domain containing 90B

chr10_+_127759721 0.620 ENSMUST00000073639.5
Rdh1
retinol dehydrogenase 1 (all trans)
chr3_-_113630068 0.616 ENSMUST00000092154.3
ENSMUST00000106536.1
ENSMUST00000106535.1
Rnpc3


RNA-binding region (RNP1, RRM) containing 3


chr19_+_26748268 0.615 ENSMUST00000175791.1
ENSMUST00000176698.1
ENSMUST00000177252.1
ENSMUST00000176475.1
ENSMUST00000112637.2
Smarca2




SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2




chr19_-_5802640 0.614 ENSMUST00000173523.1
ENSMUST00000173499.1
ENSMUST00000172812.2
Malat1


metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)


chr17_+_35470083 0.614 ENSMUST00000174525.1
ENSMUST00000068291.6
H2-Q10

histocompatibility 2, Q region locus 10

chr5_+_29735991 0.601 ENSMUST00000012734.5
Dnajb6
DnaJ (Hsp40) homolog, subfamily B, member 6
chr14_+_34375504 0.596 ENSMUST00000111908.1
Mmrn2
multimerin 2
chr4_+_42949814 0.589 ENSMUST00000037872.3
ENSMUST00000098112.2
Dnajb5

DnaJ (Hsp40) homolog, subfamily B, member 5

chrX_-_73660047 0.575 ENSMUST00000114472.1
Pnck
pregnancy upregulated non-ubiquitously expressed CaM kinase
chrX_+_74304992 0.574 ENSMUST00000015435.4
Gdi1
guanosine diphosphate (GDP) dissociation inhibitor 1
chr12_-_110695860 0.571 ENSMUST00000149189.1
Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr17_+_21491256 0.567 ENSMUST00000076664.6
Zfp53
zinc finger protein 53
chr9_+_58582240 0.566 ENSMUST00000177292.1
ENSMUST00000085651.5
Nptn

neuroplastin

chr10_-_14705459 0.562 ENSMUST00000149485.1
ENSMUST00000154132.1
Vta1

Vps20-associated 1 homolog (S. cerevisiae)

chr4_+_129287614 0.560 ENSMUST00000102599.3
Sync
syncoilin
chr8_+_71887264 0.558 ENSMUST00000034259.7
Zfp709
zinc finger protein 709
chr11_-_54860564 0.553 ENSMUST00000144164.1
Lyrm7
LYR motif containing 7
chr11_-_23497867 0.548 ENSMUST00000128559.1
ENSMUST00000147157.1
ENSMUST00000109539.1
Ahsa2


AHA1, activator of heat shock protein ATPase 2


chr8_-_105933832 0.546 ENSMUST00000034368.6
Ctrl
chymotrypsin-like
chr17_-_34972124 0.541 ENSMUST00000087328.2
ENSMUST00000179128.1
Hspa1a

heat shock protein 1A

chr1_+_153874335 0.541 ENSMUST00000055314.3
Gm5531
predicted gene 5531
chr6_+_48647224 0.539 ENSMUST00000078223.3
Gimap8
GTPase, IMAP family member 8
chr9_-_44440868 0.538 ENSMUST00000098837.1
Foxr1
forkhead box R1
chrX_-_95658379 0.535 ENSMUST00000119640.1
Zc4h2
zinc finger, C4H2 domain containing
chr19_+_46328179 0.529 ENSMUST00000026256.2
ENSMUST00000177667.1
Fbxl15

F-box and leucine-rich repeat protein 15

chr8_-_84893887 0.522 ENSMUST00000003907.7
ENSMUST00000182458.1
ENSMUST00000109745.1
ENSMUST00000142748.1
Gcdh



glutaryl-Coenzyme A dehydrogenase



chrX_+_161717055 0.517 ENSMUST00000112338.1
Rai2
retinoic acid induced 2
chr18_+_37504264 0.507 ENSMUST00000052179.6
Pcdhb20
protocadherin beta 20
chr11_+_101279092 0.501 ENSMUST00000103107.4
Cntd1
cyclin N-terminal domain containing 1
chr1_+_57774842 0.500 ENSMUST00000167085.1
Spats2l
spermatogenesis associated, serine-rich 2-like
chr4_+_148140699 0.500 ENSMUST00000140049.1
ENSMUST00000105707.1
Mad2l2

MAD2 mitotic arrest deficient-like 2

chr7_+_122067164 0.499 ENSMUST00000033158.4
Ubfd1
ubiquitin family domain containing 1
chr5_-_116288944 0.490 ENSMUST00000086483.3
Ccdc60
coiled-coil domain containing 60
chr8_+_27085520 0.490 ENSMUST00000178514.1
ENSMUST00000033876.7
Gpr124

G protein-coupled receptor 124

chr9_+_64235201 0.485 ENSMUST00000039011.3
Uchl4
ubiquitin carboxyl-terminal esterase L4
chr18_-_10706688 0.483 ENSMUST00000002549.7
ENSMUST00000117726.1
ENSMUST00000117828.1
Abhd3


abhydrolase domain containing 3


chr1_+_42952872 0.480 ENSMUST00000179766.1
Gpr45
G protein-coupled receptor 45
chr13_-_97747373 0.480 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr1_-_52817643 0.479 ENSMUST00000027271.2
Inpp1
inositol polyphosphate-1-phosphatase
chr4_-_145246855 0.478 ENSMUST00000030336.4
Tnfrsf1b
tumor necrosis factor receptor superfamily, member 1b
chr17_+_53479212 0.478 ENSMUST00000017975.5
Rab5a
RAB5A, member RAS oncogene family
chr19_+_5366764 0.476 ENSMUST00000025759.7
Eif1ad
eukaryotic translation initiation factor 1A domain containing
chr11_-_117040182 0.475 ENSMUST00000152401.1
ENSMUST00000150628.1
Gm11728

predicted gene 11728

chr1_+_57774600 0.475 ENSMUST00000167971.1
ENSMUST00000170139.1
ENSMUST00000171699.1
ENSMUST00000164302.1
Spats2l



spermatogenesis associated, serine-rich 2-like



chr15_-_3995708 0.473 ENSMUST00000046633.8
AW549877
expressed sequence AW549877
chr18_-_3337539 0.470 ENSMUST00000142690.1
ENSMUST00000025069.4
ENSMUST00000082141.5
ENSMUST00000165086.1
ENSMUST00000149803.1
Crem




cAMP responsive element modulator




chr16_+_44943737 0.470 ENSMUST00000114622.3
ENSMUST00000166731.1
Cd200r3

CD200 receptor 3

chr6_+_142345648 0.468 ENSMUST00000041852.7
Pyroxd1
pyridine nucleotide-disulphide oxidoreductase domain 1
chr9_+_58582397 0.466 ENSMUST00000176557.1
ENSMUST00000114121.4
ENSMUST00000177064.1
Nptn


neuroplastin


chr11_-_48946148 0.465 ENSMUST00000104958.1
Psme2b
protease (prosome, macropain) activator subunit 2B
chr5_+_135887905 0.463 ENSMUST00000005077.6
Hspb1
heat shock protein 1
chr13_-_51203065 0.462 ENSMUST00000091708.4
Hist1h2al
histone cluster 1, H2al
chr4_-_49593875 0.456 ENSMUST00000151542.1
Tmem246
transmembrane protein 246
chrX_-_95658416 0.454 ENSMUST00000044382.6
Zc4h2
zinc finger, C4H2 domain containing
chr6_+_125049952 0.454 ENSMUST00000088294.5
ENSMUST00000032481.7
Acrbp

proacrosin binding protein

chr12_+_111758923 0.451 ENSMUST00000118471.1
ENSMUST00000122300.1
Klc1

kinesin light chain 1

chrX_-_95658392 0.451 ENSMUST00000120620.1
Zc4h2
zinc finger, C4H2 domain containing
chr11_-_110168073 0.448 ENSMUST00000044850.3
Abca9
ATP-binding cassette, sub-family A (ABC1), member 9
chr10_-_86705485 0.448 ENSMUST00000020238.7
Hsp90b1
heat shock protein 90, beta (Grp94), member 1
chr7_-_141327700 0.446 ENSMUST00000080553.7
Deaf1
deformed epidermal autoregulatory factor 1 (Drosophila)
chr11_-_52000748 0.441 ENSMUST00000109086.1
Ube2b
ubiquitin-conjugating enzyme E2B
chr9_+_18292267 0.437 ENSMUST00000001825.7
Chordc1
cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1
chr2_-_146511992 0.437 ENSMUST00000109986.2
Ralgapa2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr16_-_20426322 0.436 ENSMUST00000115547.2
ENSMUST00000096199.4
Abcc5

ATP-binding cassette, sub-family C (CFTR/MRP), member 5

chrY_-_90754821 0.433 ENSMUST00000177893.1
Gm21860
predicted gene, 21860
chr3_+_79591356 0.433 ENSMUST00000029382.7
Ppid
peptidylprolyl isomerase D (cyclophilin D)
chr2_-_168230575 0.430 ENSMUST00000109193.1
Dpm1
dolichol-phosphate (beta-D) mannosyltransferase 1
chr10_-_120979327 0.430 ENSMUST00000119944.1
ENSMUST00000119093.1
Lemd3

LEM domain containing 3

chr5_-_33218229 0.422 ENSMUST00000046186.4
Spon2
spondin 2, extracellular matrix protein
chr11_-_93968242 0.411 ENSMUST00000107844.2
Nme1
NME/NM23 nucleoside diphosphate kinase 1
chr3_-_107943362 0.411 ENSMUST00000106683.1
Gstm6
glutathione S-transferase, mu 6
chr17_+_35236556 0.410 ENSMUST00000068261.8
Atp6v1g2
ATPase, H+ transporting, lysosomal V1 subunit G2
chr5_-_36695969 0.409 ENSMUST00000031091.9
ENSMUST00000140063.1
D5Ertd579e

DNA segment, Chr 5, ERATO Doi 579, expressed

chr10_-_86011833 0.406 ENSMUST00000105304.1
ENSMUST00000061699.5
Bpifc

BPI fold containing family C

chr17_-_12916345 0.405 ENSMUST00000079121.3
Mrpl18
mitochondrial ribosomal protein L18
chr1_+_55088132 0.402 ENSMUST00000075242.6
Hspe1
heat shock protein 1 (chaperonin 10)
chrY_-_90839177 0.397 ENSMUST00000179623.1
Gm21748
predicted gene, 21748
chr16_-_84835484 0.390 ENSMUST00000114191.1
Atp5j
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F
chr6_+_3993776 0.390 ENSMUST00000031673.5
Gngt1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chrX_+_71663665 0.390 ENSMUST00000070449.5
Gpr50
G-protein-coupled receptor 50
chr11_+_82045705 0.390 ENSMUST00000021011.2
Ccl7
chemokine (C-C motif) ligand 7
chr4_-_43653560 0.383 ENSMUST00000107870.2
Spag8
sperm associated antigen 8
chr12_+_75308308 0.379 ENSMUST00000118602.1
ENSMUST00000118966.1
ENSMUST00000055390.5
Rhoj


ras homolog gene family, member J


chr15_-_99528017 0.379 ENSMUST00000023750.7
Faim2
Fas apoptotic inhibitory molecule 2
chr10_+_29313500 0.375 ENSMUST00000020034.4
Echdc1
enoyl Coenzyme A hydratase domain containing 1
chr19_+_34290653 0.375 ENSMUST00000025691.5
ENSMUST00000112472.2
Fas

Fas (TNF receptor superfamily member 6)

chr16_-_50732707 0.373 ENSMUST00000169791.2
5330426P16Rik
RIKEN cDNA 5330426P16 gene
chr12_+_111758848 0.368 ENSMUST00000084941.5
Klc1
kinesin light chain 1
chr8_+_46986913 0.366 ENSMUST00000039840.7
ENSMUST00000119686.1
Enpp6

ectonucleotide pyrophosphatase/phosphodiesterase 6

chr18_+_77065195 0.364 ENSMUST00000114777.2
Pias2
protein inhibitor of activated STAT 2
chr2_-_168230353 0.364 ENSMUST00000154111.1
Dpm1
dolichol-phosphate (beta-D) mannosyltransferase 1
chr15_-_79658749 0.363 ENSMUST00000109646.2
Fam227a
family with sequence similarity 227, member A
chr2_-_39065505 0.362 ENSMUST00000039165.8
Golga1
golgi autoantigen, golgin subfamily a, 1
chr16_-_84835557 0.362 ENSMUST00000138279.1
ENSMUST00000023608.7
Atp5j

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F

chr5_-_92675253 0.361 ENSMUST00000151180.1
ENSMUST00000150359.1
Ccdc158

coiled-coil domain containing 158

chr5_-_45450221 0.358 ENSMUST00000015950.5
Qdpr
quinoid dihydropteridine reductase
chr11_+_97415527 0.350 ENSMUST00000121799.1
Arhgap23
Rho GTPase activating protein 23
chr16_+_21794384 0.349 ENSMUST00000180830.1
1300002E11Rik
RIKEN cDNA 1300002E11 gene
chr17_-_45592569 0.348 ENSMUST00000163492.1
Slc29a1
solute carrier family 29 (nucleoside transporters), member 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.8 4.6 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.8 2.3 GO:0035799 ureter maturation(GO:0035799)
0.7 4.4 GO:0045583 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.7 2.8 GO:0044565 dendritic cell proliferation(GO:0044565)
0.5 2.0 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.4 2.1 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.4 1.2 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.4 1.1 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.3 1.0 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.3 1.3 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
0.3 0.9 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.3 0.9 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.3 1.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.3 0.8 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.3 1.8 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.2 1.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.2 1.0 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.2 0.7 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
0.2 0.7 GO:1902605 heterotrimeric G-protein complex assembly(GO:1902605)
0.2 1.0 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.2 1.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.2 1.8 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.2 0.8 GO:0007412 axon target recognition(GO:0007412)
0.2 1.2 GO:0090383 phagosome acidification(GO:0090383)
0.2 0.7 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.2 0.7 GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
0.2 1.0 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606) detection of bacterium(GO:0016045) detection of other organism(GO:0098543)
0.2 0.8 GO:0035617 stress granule disassembly(GO:0035617)
0.2 2.1 GO:1902018 regulation of mitotic spindle assembly(GO:1901673) negative regulation of cilium assembly(GO:1902018)
0.2 0.2 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.4 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.6 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.4 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.1 0.8 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.1 0.8 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.1 0.5 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 0.6 GO:0035063 nuclear speck organization(GO:0035063)
0.1 1.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.1 0.2 GO:0035771 interleukin-4-mediated signaling pathway(GO:0035771)
0.1 1.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 0.8 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 0.8 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.9 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 0.8 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.1 0.5 GO:0042891 antibiotic transport(GO:0042891) dipeptide transport(GO:0042938)
0.1 0.3 GO:0035963 response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.1 0.7 GO:0001955 blood vessel maturation(GO:0001955)
0.1 0.9 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.1 0.4 GO:0060178 regulation of exocyst localization(GO:0060178)
0.1 0.4 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.3 GO:0015793 glycerol transport(GO:0015793)
0.1 0.2 GO:1904154 protein localization to endoplasmic reticulum exit site(GO:0070973) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.1 0.8 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 0.3 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1 0.5 GO:0015862 uridine transport(GO:0015862)
0.1 0.4 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.1 0.2 GO:0009838 abscission(GO:0009838)
0.1 0.4 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.1 1.4 GO:0016486 peptide hormone processing(GO:0016486)
0.1 0.4 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.1 0.2 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.1 0.2 GO:0036233 glycine import(GO:0036233)
0.1 0.6 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 0.5 GO:0051036 regulation of endosome size(GO:0051036) receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 0.9 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 0.3 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.1 0.6 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.1 0.9 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 0.7 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.1 0.4 GO:0019695 choline metabolic process(GO:0019695)
0.1 0.2 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
0.1 0.2 GO:0032627 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667)
0.1 1.7 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1 0.7 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.6 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.2 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.0 0.4 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.2 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.8 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.1 GO:0019043 establishment of viral latency(GO:0019043)
0.0 0.2 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.0 0.3 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.4 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.4 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0 0.5 GO:0035337 fatty-acyl-CoA metabolic process(GO:0035337)
0.0 0.1 GO:0048550 negative regulation of pinocytosis(GO:0048550)
0.0 0.7 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.4 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.7 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 0.1 GO:0002842 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) positive regulation of T cell mediated immune response to tumor cell(GO:0002842) protein import into mitochondrial intermembrane space(GO:0045041)
0.0 0.7 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.4 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.7 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.4 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.3 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 1.8 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.2 GO:0061450 trophoblast cell migration(GO:0061450) regulation of trophoblast cell migration(GO:1901163) positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.2 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.3 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.3 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.4 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.4 GO:0007602 phototransduction(GO:0007602)
0.0 0.8 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.1 GO:0032364 oxygen homeostasis(GO:0032364)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.4 GO:0033599 regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.0 0.9 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.1 GO:0016598 protein arginylation(GO:0016598)
0.0 0.6 GO:0045103 intermediate filament-based process(GO:0045103)
0.0 0.3 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.8 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.6 GO:0001523 retinoid metabolic process(GO:0001523)
0.0 0.1 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.0 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 1.3 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 1.0 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 1.7 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 0.5 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 1.2 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.2 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.1 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.0 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.2 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.4 GO:0021702 cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.5 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 0.0 GO:2000812 response to rapamycin(GO:1901355) regulation of barbed-end actin filament capping(GO:2000812)
0.0 0.5 GO:0070232 regulation of T cell apoptotic process(GO:0070232)
0.0 0.2 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.0 0.6 GO:0000266 mitochondrial fission(GO:0000266)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.4 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.3 2.0 GO:0097512 cardiac myofibril(GO:0097512)
0.2 0.8 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.2 2.4 GO:0042612 MHC class I protein complex(GO:0042612)
0.2 0.7 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 1.1 GO:0033503 HULC complex(GO:0033503)
0.2 0.5 GO:0098842 postsynaptic early endosome(GO:0098842)
0.1 0.9 GO:0000938 GARP complex(GO:0000938)
0.1 1.0 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 1.2 GO:0042629 mast cell granule(GO:0042629)
0.1 0.9 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.7 GO:0005955 calcineurin complex(GO:0005955)
0.1 1.4 GO:0046930 pore complex(GO:0046930)
0.1 0.8 GO:0031415 NatA complex(GO:0031415)
0.1 0.8 GO:0097433 dense body(GO:0097433)
0.1 0.5 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 3.9 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 1.0 GO:0042588 zymogen granule(GO:0042588)
0.1 0.4 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 1.0 GO:0000800 lateral element(GO:0000800)
0.1 0.4 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.1 0.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 1.1 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.8 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.3 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.6 GO:0071564 npBAF complex(GO:0071564)
0.0 0.3 GO:0042382 paraspeckles(GO:0042382)
0.0 0.7 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 1.2 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.5 GO:0043196 varicosity(GO:0043196)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 2.3 GO:0072562 blood microparticle(GO:0072562)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.4 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.2 GO:0090543 Flemming body(GO:0090543)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.1 GO:0097361 CIA complex(GO:0097361)
0.0 0.6 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.0 GO:0036379 myofilament(GO:0036379)
0.0 0.3 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 2.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.2 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.6 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.3 GO:0031526 brush border membrane(GO:0031526)
0.0 2.2 GO:0030017 sarcomere(GO:0030017)
0.0 1.0 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.4 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.5 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.8 GO:0030141 secretory granule(GO:0030141)
0.0 0.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.0 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.1 GO:0005921 gap junction(GO:0005921)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.6 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.6 4.4 GO:0030911 TPR domain binding(GO:0030911)
0.4 1.9 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.4 2.6 GO:0043199 sulfate binding(GO:0043199)
0.3 0.9 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.3 0.9 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.3 0.9 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
0.3 2.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.2 1.0 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.2 1.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.2 1.0 GO:0050700 CARD domain binding(GO:0050700)
0.2 0.8 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.2 0.8 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.2 0.8 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.2 2.4 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.2 0.5 GO:0042936 dipeptide transporter activity(GO:0042936)
0.2 0.5 GO:0052740 phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.2 1.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.2 0.5 GO:0005118 sevenless binding(GO:0005118)
0.1 0.6 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.1 1.2 GO:0005523 tropomyosin binding(GO:0005523)
0.1 1.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.7 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 0.4 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 0.4 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.1 0.4 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.1 0.7 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)
0.1 1.0 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 0.7 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 0.8 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 0.3 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 0.3 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.1 0.4 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 0.7 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.3 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.7 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 0.3 GO:0034618 arginine binding(GO:0034618)
0.1 0.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.9 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 2.6 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.7 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.2 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 0.6 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 0.3 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 0.4 GO:0046790 virion binding(GO:0046790)
0.1 0.4 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.8 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 0.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.2 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 2.1 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.5 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 3.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 1.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.3 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 1.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 1.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.5 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.3 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 0.4 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.5 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.5 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.0 0.8 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.5 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.2 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.8 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.7 GO:0030291 protein serine/threonine kinase inhibitor activity(GO:0030291)
0.0 0.0 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.3 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.7 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 1.4 GO:0051213 dioxygenase activity(GO:0051213)
0.0 0.1 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.6 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.0 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.2 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.4 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.1 0.4 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 4.5 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.1 0.5 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 0.7 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 0.4 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 1.1 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 3.6 PID_CMYB_PATHWAY C-MYB transcription factor network
0.0 1.8 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.2 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.0 0.7 PID_IL2_1PATHWAY IL2-mediated signaling events
0.0 0.8 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.5 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.6 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 1.4 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 0.8 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 0.4 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 0.2 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.0 0.2 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.8 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.7 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.3 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.0 0.2 ST_INTERLEUKIN_4_PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.4 PID_FAS_PATHWAY FAS (CD95) signaling pathway
0.0 0.2 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.8 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 4.4 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 2.6 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 2.4 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.1 0.4 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 0.6 REACTOME_ER_PHAGOSOME_PATHWAY Genes involved in ER-Phagosome pathway
0.1 1.6 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.4 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.8 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.2 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.8 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.8 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.7 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.0 5.6 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.8 REACTOME_KINESINS Genes involved in Kinesins
0.0 0.4 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.9 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.9 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.7 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.6 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.4 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.5 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.9 REACTOME_RNA_POL_I_TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
0.0 0.1 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.4 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.0 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.8 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.3 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation