Motif ID: Pax2

Z-value: 1.021


Transcription factors associated with Pax2:

Gene SymbolEntrez IDGene Name
Pax2 ENSMUSG00000004231.9 Pax2



Activity profile for motif Pax2.

activity profile for motif Pax2


Sorted Z-values histogram for motif Pax2

Sorted Z-values for motif Pax2



Network of associatons between targets according to the STRING database.



First level regulatory network of Pax2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_-_45158183 3.878 ENSMUST00000114600.1
Slc35a5
solute carrier family 35, member A5
chr17_+_26715644 3.647 ENSMUST00000062519.7
ENSMUST00000144221.1
ENSMUST00000142539.1
ENSMUST00000151681.1
Crebrf



CREB3 regulatory factor



chr16_-_45158566 3.276 ENSMUST00000181177.1
Slc35a5
solute carrier family 35, member A5
chr4_+_148039097 3.236 ENSMUST00000141283.1
Mthfr
5,10-methylenetetrahydrofolate reductase
chr4_+_148039035 3.205 ENSMUST00000097788.4
Mthfr
5,10-methylenetetrahydrofolate reductase
chr16_-_45158624 3.123 ENSMUST00000180636.1
Slc35a5
solute carrier family 35, member A5
chr13_+_13590402 2.837 ENSMUST00000110559.1
Lyst
lysosomal trafficking regulator
chr19_-_7105729 2.725 ENSMUST00000113383.2
Flrt1
fibronectin leucine rich transmembrane protein 1
chr12_-_102878406 2.701 ENSMUST00000045652.6
Btbd7
BTB (POZ) domain containing 7
chr6_+_17463927 2.526 ENSMUST00000115442.1
Met
met proto-oncogene
chr16_-_45158453 2.519 ENSMUST00000181750.1
Slc35a5
solute carrier family 35, member A5
chr16_-_45158650 2.484 ENSMUST00000023344.3
Slc35a5
solute carrier family 35, member A5
chr16_+_94370786 2.479 ENSMUST00000147046.1
ENSMUST00000149885.1
ENSMUST00000127667.1
ENSMUST00000119131.1
ENSMUST00000145883.1
Ttc3




tetratricopeptide repeat domain 3




chr10_+_111164794 2.422 ENSMUST00000105275.1
ENSMUST00000095310.1
Osbpl8

oxysterol binding protein-like 8

chr2_+_48949495 2.302 ENSMUST00000112745.1
Mbd5
methyl-CpG binding domain protein 5
chr2_+_119897212 2.289 ENSMUST00000046717.6
ENSMUST00000110774.1
ENSMUST00000110773.2
ENSMUST00000079934.5
ENSMUST00000156510.1
Mga




MAX gene associated




chr9_+_70679016 2.103 ENSMUST00000144537.1
Adam10
a disintegrin and metallopeptidase domain 10
chr9_+_46012822 1.901 ENSMUST00000120463.2
ENSMUST00000120247.1
Sik3

SIK family kinase 3

chr4_-_148038769 1.898 ENSMUST00000030879.5
ENSMUST00000137724.1
Clcn6

chloride channel 6

chr5_+_15934762 1.894 ENSMUST00000115281.2
Cacna2d1
calcium channel, voltage-dependent, alpha2/delta subunit 1
chr10_-_109823585 1.792 ENSMUST00000161582.1
Nav3
neuron navigator 3
chr15_-_77956658 1.745 ENSMUST00000117725.1
ENSMUST00000016696.6
Foxred2

FAD-dependent oxidoreductase domain containing 2

chr5_-_124425572 1.728 ENSMUST00000168651.1
Sbno1
sno, strawberry notch homolog 1 (Drosophila)
chr16_-_44139003 1.714 ENSMUST00000124102.1
Atp6v1a
ATPase, H+ transporting, lysosomal V1 subunit A
chr4_-_11966368 1.702 ENSMUST00000056050.4
ENSMUST00000108299.1
ENSMUST00000108297.2
Pdp1


pyruvate dehyrogenase phosphatase catalytic subunit 1


chr9_+_64811313 1.673 ENSMUST00000038890.5
Dennd4a
DENN/MADD domain containing 4A
chr16_-_44139630 1.671 ENSMUST00000137557.1
ENSMUST00000147025.1
Atp6v1a

ATPase, H+ transporting, lysosomal V1 subunit A

chr14_+_31019159 1.649 ENSMUST00000112094.1
ENSMUST00000144009.1
Pbrm1

polybromo 1

chr16_+_94370618 1.632 ENSMUST00000117648.1
ENSMUST00000147352.1
ENSMUST00000150346.1
ENSMUST00000155692.1
ENSMUST00000153988.1
ENSMUST00000141856.1
ENSMUST00000152117.1
ENSMUST00000150097.1
ENSMUST00000122895.1
ENSMUST00000151770.1
Ttc3









tetratricopeptide repeat domain 3









chr11_+_53350783 1.628 ENSMUST00000060945.5
Aff4
AF4/FMR2 family, member 4
chr12_-_101028983 1.608 ENSMUST00000068411.3
ENSMUST00000085096.3
Ccdc88c

coiled-coil domain containing 88C

chr9_-_42124276 1.592 ENSMUST00000060989.8
Sorl1
sortilin-related receptor, LDLR class A repeats-containing
chr15_+_39198244 1.584 ENSMUST00000082054.5
ENSMUST00000042917.9
Rims2

regulating synaptic membrane exocytosis 2

chr12_+_72441852 1.581 ENSMUST00000162159.1
Lrrc9
leucine rich repeat containing 9
chr11_-_120630516 1.580 ENSMUST00000106181.1
Mafg
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr5_-_106458440 1.578 ENSMUST00000086795.6
Barhl2
BarH-like 2 (Drosophila)
chr15_+_81400132 1.527 ENSMUST00000163754.1
ENSMUST00000041609.4
Xpnpep3

X-prolyl aminopeptidase (aminopeptidase P) 3, putative

chr17_-_66077022 1.520 ENSMUST00000150766.1
ENSMUST00000038116.5
Ankrd12

ankyrin repeat domain 12

chr2_-_121271315 1.512 ENSMUST00000131245.1
Trp53bp1
transformation related protein 53 binding protein 1
chr7_-_63212514 1.507 ENSMUST00000032738.5
Chrna7
cholinergic receptor, nicotinic, alpha polypeptide 7
chr5_+_15934685 1.505 ENSMUST00000078272.6
ENSMUST00000180204.1
ENSMUST00000167946.2
ENSMUST00000101581.3
ENSMUST00000039370.7
Cacna2d1




calcium channel, voltage-dependent, alpha2/delta subunit 1




chr5_+_64803513 1.500 ENSMUST00000165536.1
Klf3
Kruppel-like factor 3 (basic)
chr7_+_47050628 1.477 ENSMUST00000010451.5
Tmem86a
transmembrane protein 86A
chr11_+_35769462 1.468 ENSMUST00000018990.7
Pank3
pantothenate kinase 3
chr6_+_143167210 1.438 ENSMUST00000032413.4
Etnk1
ethanolamine kinase 1
chr11_-_120630126 1.430 ENSMUST00000106180.1
Mafg
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr12_-_55821157 1.417 ENSMUST00000110687.1
ENSMUST00000085385.5
Ralgapa1

Ral GTPase activating protein, alpha subunit 1

chr1_-_82291370 1.412 ENSMUST00000069799.2
Irs1
insulin receptor substrate 1
chr14_+_55560010 1.392 ENSMUST00000147981.1
ENSMUST00000133256.1
Dcaf11

DDB1 and CUL4 associated factor 11

chr12_+_72441933 1.384 ENSMUST00000161284.1
Lrrc9
leucine rich repeat containing 9
chr17_+_46383725 1.368 ENSMUST00000113481.1
ENSMUST00000138127.1
Zfp318

zinc finger protein 318

chr4_+_48585276 1.296 ENSMUST00000123476.1
Tmeff1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr7_+_125707945 1.290 ENSMUST00000148701.1
D430042O09Rik
RIKEN cDNA D430042O09 gene
chr2_+_126707319 1.283 ENSMUST00000028841.7
ENSMUST00000110416.2
Usp8

ubiquitin specific peptidase 8

chr18_+_60526194 1.283 ENSMUST00000025505.5
Dctn4
dynactin 4
chr5_+_138171997 1.265 ENSMUST00000019662.4
ENSMUST00000151318.1
Ap4m1

adaptor-related protein complex AP-4, mu 1

chr1_-_183297256 1.257 ENSMUST00000163528.2
Brox
BRO1 domain and CAAX motif containing
chr1_+_87327008 1.251 ENSMUST00000172794.1
ENSMUST00000164992.2
Gigyf2

GRB10 interacting GYF protein 2

chr3_-_133544390 1.240 ENSMUST00000098603.3
Tet2
tet methylcytosine dioxygenase 2
chr2_+_155382186 1.223 ENSMUST00000134218.1
Trp53inp2
transformation related protein 53 inducible nuclear protein 2
chr9_+_46012810 1.173 ENSMUST00000126865.1
Sik3
SIK family kinase 3
chr7_+_28179469 1.161 ENSMUST00000085901.6
ENSMUST00000172761.1
Dyrk1b

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b

chr6_-_39725193 1.154 ENSMUST00000101497.3
Braf
Braf transforming gene
chr1_+_87327044 1.141 ENSMUST00000173173.1
Gigyf2
GRB10 interacting GYF protein 2
chr2_+_119594288 1.133 ENSMUST00000147425.1
ENSMUST00000153581.1
1700020I14Rik

RIKEN cDNA 1700020I14 gene

chr14_+_34673948 1.129 ENSMUST00000090027.3
Wapal
wings apart-like homolog (Drosophila)
chr16_+_8830093 1.106 ENSMUST00000023150.5
1810013L24Rik
RIKEN cDNA 1810013L24 gene
chr16_-_44139196 1.085 ENSMUST00000063661.6
ENSMUST00000114666.2
Atp6v1a

ATPase, H+ transporting, lysosomal V1 subunit A

chr14_+_34674122 1.083 ENSMUST00000169910.1
Wapal
wings apart-like homolog (Drosophila)
chr19_-_57008187 1.069 ENSMUST00000118800.1
ENSMUST00000111584.2
ENSMUST00000122359.1
ENSMUST00000148049.1
Afap1l2



actin filament associated protein 1-like 2



chr7_+_122067164 1.065 ENSMUST00000033158.4
Ubfd1
ubiquitin family domain containing 1
chr3_-_127162328 1.056 ENSMUST00000182994.1
Ank2
ankyrin 2, brain
chr14_-_73325773 1.040 ENSMUST00000022701.6
Rb1
retinoblastoma 1
chr4_+_109000770 1.024 ENSMUST00000106644.2
Nrd1
nardilysin, N-arginine dibasic convertase, NRD convertase 1
chr9_-_95511897 1.014 ENSMUST00000079659.5
ENSMUST00000078374.6
U2surp

U2 snRNP-associated SURP domain containing

chr9_-_66834648 1.003 ENSMUST00000057261.8
ENSMUST00000169282.1
Aph1c

anterior pharynx defective 1c homolog (C. elegans)

chr14_+_31019183 1.001 ENSMUST00000052239.5
Pbrm1
polybromo 1
chr14_+_31019125 0.995 ENSMUST00000112095.1
ENSMUST00000112098.3
ENSMUST00000112106.1
ENSMUST00000146325.1
Pbrm1



polybromo 1



chr1_-_130715734 0.995 ENSMUST00000066863.6
ENSMUST00000050406.4
Pfkfb2

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

chr17_+_93199348 0.991 ENSMUST00000064775.6
Adcyap1
adenylate cyclase activating polypeptide 1
chr4_-_45084538 0.990 ENSMUST00000052236.6
Fbxo10
F-box protein 10
chr4_+_127077374 0.984 ENSMUST00000046751.6
ENSMUST00000094713.3
Zmym6

zinc finger, MYM-type 6

chr14_-_18239053 0.983 ENSMUST00000090543.5
Nr1d2
nuclear receptor subfamily 1, group D, member 2
chr4_+_48585193 0.955 ENSMUST00000107703.1
Tmeff1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr8_+_83165348 0.952 ENSMUST00000034145.4
Tbc1d9
TBC1 domain family, member 9
chr16_+_5050012 0.935 ENSMUST00000052449.5
Ubn1
ubinuclein 1
chr2_-_169405435 0.934 ENSMUST00000131509.1
4930529I22Rik
RIKEN cDNA 4930529I22 gene
chr7_+_19131686 0.931 ENSMUST00000165913.1
Fbxo46
F-box protein 46
chr15_+_66577536 0.919 ENSMUST00000048188.8
Phf20l1
PHD finger protein 20-like 1
chr11_-_86757483 0.916 ENSMUST00000060766.9
ENSMUST00000103186.4
Cltc

clathrin, heavy polypeptide (Hc)

chr2_-_37703845 0.913 ENSMUST00000155237.1
Strbp
spermatid perinuclear RNA binding protein
chr2_+_166805506 0.912 ENSMUST00000099078.3
Arfgef2
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr1_-_183297008 0.903 ENSMUST00000057062.5
Brox
BRO1 domain and CAAX motif containing
chr5_-_124425907 0.894 ENSMUST00000065263.5
Sbno1
sno, strawberry notch homolog 1 (Drosophila)
chr14_+_21500879 0.892 ENSMUST00000182964.1
Kat6b
K(lysine) acetyltransferase 6B
chr7_-_37773555 0.889 ENSMUST00000176534.1
Zfp536
zinc finger protein 536
chr4_-_126202583 0.888 ENSMUST00000106142.1
ENSMUST00000169403.1
ENSMUST00000130334.1
Thrap3


thyroid hormone receptor associated protein 3


chr12_-_84450944 0.874 ENSMUST00000085192.5
Aldh6a1
aldehyde dehydrogenase family 6, subfamily A1
chr5_-_65697856 0.861 ENSMUST00000031104.6
Pds5a
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr2_+_3513035 0.858 ENSMUST00000036350.2
Cdnf
cerebral dopamine neurotrophic factor
chrX_-_94123087 0.847 ENSMUST00000113925.1
Zfx
zinc finger protein X-linked
chr9_+_70678950 0.843 ENSMUST00000067880.6
Adam10
a disintegrin and metallopeptidase domain 10
chr9_+_111311674 0.840 ENSMUST00000078626.3
Trank1
tetratricopeptide repeat and ankyrin repeat containing 1
chr2_-_164833438 0.834 ENSMUST00000042775.4
Neurl2
neuralized-like 2 (Drosophila)
chr1_-_10232670 0.833 ENSMUST00000088615.4
ENSMUST00000131556.1
Arfgef1

ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)

chr9_-_91365756 0.831 ENSMUST00000034927.6
Zic1
zinc finger protein of the cerebellum 1
chrX_+_166344692 0.828 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
Gpm6b





glycoprotein m6b





chr2_-_37422869 0.827 ENSMUST00000112936.1
ENSMUST00000112934.1
Rc3h2

ring finger and CCCH-type zinc finger domains 2

chr19_-_60581013 0.812 ENSMUST00000111460.3
ENSMUST00000081790.7
ENSMUST00000166712.1
Cacul1


CDK2 associated, cullin domain 1


chr16_-_4679703 0.800 ENSMUST00000038552.6
ENSMUST00000090480.4
Coro7

coronin 7

chr5_+_65199691 0.779 ENSMUST00000041892.8
Wdr19
WD repeat domain 19
chr15_+_86058727 0.773 ENSMUST00000138134.1
Gramd4
GRAM domain containing 4
chr4_-_58911902 0.773 ENSMUST00000134848.1
ENSMUST00000107557.2
ENSMUST00000149301.1
AI314180


expressed sequence AI314180


chr18_+_31609512 0.768 ENSMUST00000164667.1
B930094E09Rik
RIKEN cDNA B930094E09 gene
chr11_-_101170327 0.758 ENSMUST00000123864.1
Plekhh3
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr4_+_109000606 0.753 ENSMUST00000065977.4
ENSMUST00000102736.2
Nrd1

nardilysin, N-arginine dibasic convertase, NRD convertase 1

chr7_+_110018301 0.750 ENSMUST00000084731.3
Ipo7
importin 7
chr2_+_155381808 0.748 ENSMUST00000043237.7
ENSMUST00000174685.1
Trp53inp2

transformation related protein 53 inducible nuclear protein 2

chr17_-_90088343 0.743 ENSMUST00000173917.1
Nrxn1
neurexin I
chr9_-_91365778 0.738 ENSMUST00000065360.3
Zic1
zinc finger protein of the cerebellum 1
chr11_-_79254663 0.738 ENSMUST00000017821.5
Wsb1
WD repeat and SOCS box-containing 1
chr18_+_63708689 0.735 ENSMUST00000072726.5
Wdr7
WD repeat domain 7
chr6_-_39725448 0.731 ENSMUST00000002487.8
Braf
Braf transforming gene
chr7_+_125707893 0.722 ENSMUST00000069660.6
ENSMUST00000142464.1
D430042O09Rik

RIKEN cDNA D430042O09 gene

chr2_+_30286406 0.720 ENSMUST00000138666.1
ENSMUST00000113634.2
Nup188

nucleoporin 188

chr13_-_107890059 0.716 ENSMUST00000105097.2
Zswim6
zinc finger SWIM-type containing 6
chr14_-_72602945 0.695 ENSMUST00000162825.1
Fndc3a
fibronectin type III domain containing 3A
chr9_-_110408160 0.691 ENSMUST00000040021.7
Ptpn23
protein tyrosine phosphatase, non-receptor type 23
chr8_+_107436355 0.691 ENSMUST00000166615.1
Wwp2
WW domain containing E3 ubiquitin protein ligase 2
chr4_-_149774238 0.690 ENSMUST00000105686.2
Slc25a33
solute carrier family 25, member 33
chr9_+_58582240 0.687 ENSMUST00000177292.1
ENSMUST00000085651.5
Nptn

neuroplastin

chr2_-_121271341 0.677 ENSMUST00000110647.1
Trp53bp1
transformation related protein 53 binding protein 1
chr2_+_71786923 0.676 ENSMUST00000112101.1
ENSMUST00000028522.3
Itga6

integrin alpha 6

chr8_+_126298526 0.672 ENSMUST00000108759.2
Slc35f3
solute carrier family 35, member F3
chr7_-_46795661 0.666 ENSMUST00000123725.1
Hps5
Hermansky-Pudlak syndrome 5 homolog (human)
chr10_-_29362012 0.665 ENSMUST00000161508.1
Rnf146
ring finger protein 146
chr2_+_129198757 0.661 ENSMUST00000028880.3
Slc20a1
solute carrier family 20, member 1
chr16_-_97962581 0.631 ENSMUST00000113734.2
ENSMUST00000052089.7
ENSMUST00000063605.7
Zbtb21


zinc finger and BTB domain containing 21


chr2_-_26237368 0.615 ENSMUST00000036187.8
Qsox2
quiescin Q6 sulfhydryl oxidase 2
chr6_-_113531575 0.614 ENSMUST00000032425.5
Emc3
ER membrane protein complex subunit 3
chr13_-_46727932 0.602 ENSMUST00000021803.9
Nup153
nucleoporin 153
chr1_+_87326997 0.602 ENSMUST00000027475.8
Gigyf2
GRB10 interacting GYF protein 2
chr9_+_58582397 0.597 ENSMUST00000176557.1
ENSMUST00000114121.4
ENSMUST00000177064.1
Nptn


neuroplastin


chr19_+_45047557 0.588 ENSMUST00000062213.5
ENSMUST00000111954.4
ENSMUST00000084493.6
Sfxn3


sideroflexin 3


chr2_-_167492826 0.588 ENSMUST00000109211.2
ENSMUST00000057627.9
Spata2

spermatogenesis associated 2

chr7_+_90130227 0.583 ENSMUST00000049537.7
Picalm
phosphatidylinositol binding clathrin assembly protein
chr10_-_127211528 0.572 ENSMUST00000013970.7
Pip4k2c
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr14_+_55560480 0.570 ENSMUST00000121622.1
ENSMUST00000143431.1
ENSMUST00000150481.1
Dcaf11


DDB1 and CUL4 associated factor 11


chr11_-_119040905 0.564 ENSMUST00000026663.7
Cbx8
chromobox 8
chr5_+_117363513 0.556 ENSMUST00000111959.1
Wsb2
WD repeat and SOCS box-containing 2
chr5_-_114773372 0.555 ENSMUST00000112183.1
ENSMUST00000086564.4
Git2

G protein-coupled receptor kinase-interactor 2

chr16_+_77014069 0.543 ENSMUST00000023580.6
Usp25
ubiquitin specific peptidase 25
chr5_-_114773488 0.542 ENSMUST00000178440.1
ENSMUST00000043283.7
ENSMUST00000112185.2
Git2


G protein-coupled receptor kinase-interactor 2


chr17_+_83350925 0.533 ENSMUST00000096766.4
ENSMUST00000112363.2
ENSMUST00000049503.8
Eml4


echinoderm microtubule associated protein like 4


chr2_-_121271403 0.528 ENSMUST00000110648.1
Trp53bp1
transformation related protein 53 binding protein 1
chr6_-_149188648 0.524 ENSMUST00000095319.3
ENSMUST00000141346.1
ENSMUST00000111535.1
Amn1


antagonist of mitotic exit network 1


chr1_+_128244122 0.523 ENSMUST00000027592.3
Ubxn4
UBX domain protein 4
chr4_-_62360436 0.519 ENSMUST00000084527.3
ENSMUST00000098033.3
Fkbp15

FK506 binding protein 15

chr18_-_31609893 0.513 ENSMUST00000060396.6
Slc25a46
solute carrier family 25, member 46
chr1_+_167001417 0.513 ENSMUST00000165874.1
Fam78b
family with sequence similarity 78, member B
chr18_+_36281069 0.511 ENSMUST00000051301.3
Pura
purine rich element binding protein A
chr2_+_130406478 0.508 ENSMUST00000055421.4
Tmem239
transmembrane 239
chr13_-_64274962 0.504 ENSMUST00000039318.8
Cdc14b
CDC14 cell division cycle 14B
chr1_-_133661318 0.504 ENSMUST00000027736.6
ENSMUST00000179598.1
Zc3h11a
Zbed6
zinc finger CCCH type containing 11A
zinc finger, BED domain containing 6
chr3_+_116562965 0.502 ENSMUST00000029573.5
Lrrc39
leucine rich repeat containing 39
chr4_-_126202335 0.494 ENSMUST00000142125.1
ENSMUST00000106141.2
Thrap3

thyroid hormone receptor associated protein 3

chr9_+_59539643 0.491 ENSMUST00000026262.6
Hexa
hexosaminidase A
chr10_-_29362032 0.475 ENSMUST00000160372.1
Rnf146
ring finger protein 146
chr18_+_34861200 0.475 ENSMUST00000165033.1
Egr1
early growth response 1
chr14_+_34673888 0.460 ENSMUST00000048263.7
Wapal
wings apart-like homolog (Drosophila)
chr18_+_23752333 0.455 ENSMUST00000170802.1
ENSMUST00000155708.1
ENSMUST00000118826.2
Mapre2


microtubule-associated protein, RP/EB family, member 2


chr15_-_53346118 0.452 ENSMUST00000077273.2
Ext1
exostoses (multiple) 1
chr17_+_24850484 0.442 ENSMUST00000118788.1
Hagh
hydroxyacyl glutathione hydrolase
chr17_+_44188564 0.438 ENSMUST00000024755.5
Clic5
chloride intracellular channel 5
chr9_+_108002501 0.431 ENSMUST00000035214.4
ENSMUST00000175874.1
Ip6k1

inositol hexaphosphate kinase 1

chr4_-_155345696 0.426 ENSMUST00000103178.4
Prkcz
protein kinase C, zeta
chr2_-_28916412 0.417 ENSMUST00000050776.2
ENSMUST00000113849.1
Barhl1

BarH-like 1 (Drosophila)

chr14_+_55560904 0.417 ENSMUST00000072530.4
ENSMUST00000128490.1
Dcaf11

DDB1 and CUL4 associated factor 11

chrX_-_94123359 0.410 ENSMUST00000137853.1
ENSMUST00000088102.5
ENSMUST00000113927.1
Zfx


zinc finger protein X-linked


chr6_+_116338013 0.394 ENSMUST00000079012.6
ENSMUST00000101032.3
March8

membrane-associated ring finger (C3HC4) 8

chr10_-_63339023 0.391 ENSMUST00000177694.1
ENSMUST00000020257.6
ENSMUST00000105442.2
Sirt1


sirtuin 1


chr17_+_35089229 0.371 ENSMUST00000007251.7
Abhd16a
abhydrolase domain containing 16A
chr7_-_127946725 0.357 ENSMUST00000118755.1
ENSMUST00000094026.3
Prss36

protease, serine, 36

chr12_+_84451485 0.356 ENSMUST00000137170.1
Lin52
lin-52 homolog (C. elegans)
chr11_-_116086929 0.352 ENSMUST00000074628.6
ENSMUST00000106444.3
Wbp2

WW domain binding protein 2

chr7_-_46795881 0.351 ENSMUST00000107653.1
ENSMUST00000107654.1
ENSMUST00000014562.7
ENSMUST00000152759.1
Hps5



Hermansky-Pudlak syndrome 5 homolog (human)



chr16_+_58727910 0.349 ENSMUST00000023426.5
ENSMUST00000162057.1
ENSMUST00000162191.1
Cldn25


claudin 25


chrX_+_68678624 0.346 ENSMUST00000114656.1
Fmr1
fragile X mental retardation syndrome 1
chr7_-_19629355 0.345 ENSMUST00000049912.8
ENSMUST00000094762.3
ENSMUST00000098754.4
Relb


avian reticuloendotheliosis viral (v-rel) oncogene related B


chr4_+_62360695 0.344 ENSMUST00000084526.5
Slc31a1
solute carrier family 31, member 1
chr19_+_21653302 0.332 ENSMUST00000052556.3
Abhd17b
abhydrolase domain containing 17B
chr4_-_46389391 0.306 ENSMUST00000086563.4
ENSMUST00000030015.5
5830415F09Rik

RIKEN cDNA 5830415F09 gene

chrX_+_68678541 0.303 ENSMUST00000088546.5
Fmr1
fragile X mental retardation syndrome 1
chr18_+_23803962 0.300 ENSMUST00000025127.3
Mapre2
microtubule-associated protein, RP/EB family, member 2
chr1_+_183297060 0.290 ENSMUST00000109166.2
Aida
axin interactor, dorsalization associated
chr2_+_164025450 0.287 ENSMUST00000067715.4
Pabpc1l
poly(A) binding protein, cytoplasmic 1-like
chr15_-_79834261 0.268 ENSMUST00000148358.1
Cbx6
chromobox 6
chr3_+_95318782 0.268 ENSMUST00000139866.1
Cers2
ceramide synthase 2
chr1_+_167001457 0.254 ENSMUST00000126198.1
Fam78b
family with sequence similarity 78, member B
chr5_+_30647921 0.248 ENSMUST00000062962.5
Slc35f6
solute carrier family 35, member F6

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.4 GO:0070829 heterochromatin maintenance(GO:0070829)
1.2 3.6 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.9 2.8 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.8 3.4 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.8 2.4 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.8 2.3 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.7 3.6 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.6 2.9 GO:0042117 monocyte activation(GO:0042117)
0.5 1.5 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978)
0.5 2.4 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.4 2.2 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
0.4 1.2 GO:0019858 cytosine metabolic process(GO:0019858)
0.4 2.5 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.3 1.0 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.3 2.5 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.3 0.9 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.3 0.9 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.3 1.3 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.2 1.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.2 0.7 GO:0061357 Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356) positive regulation of Wnt protein secretion(GO:0061357)
0.2 2.7 GO:0060693 regulation of branching involved in salivary gland morphogenesis(GO:0060693)
0.2 0.8 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.2 0.6 GO:0032240 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.2 0.4 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.2 0.8 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) myotome development(GO:0061055)
0.2 3.8 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.2 0.7 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
0.2 2.7 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.2 1.6 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.2 0.7 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.2 0.7 GO:0015888 thiamine transport(GO:0015888)
0.2 0.8 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.2 0.5 GO:0072223 metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
0.1 0.4 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.1 1.1 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1 1.7 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.7 GO:0035878 nail development(GO:0035878)
0.1 3.0 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.1 0.5 GO:0006689 ganglioside catabolic process(GO:0006689)
0.1 0.3 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.1 1.5 GO:0003094 glomerular filtration(GO:0003094)
0.1 0.6 GO:0044375 regulation of peroxisome size(GO:0044375)
0.1 1.0 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1 0.3 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.1 1.8 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 15.1 GO:0008643 carbohydrate transport(GO:0008643)
0.1 0.4 GO:0002024 diet induced thermogenesis(GO:0002024)
0.1 1.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.8 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.1 1.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 3.1 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.1 0.4 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.1 0.4 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.1 0.2 GO:2000510 positive regulation of dendritic cell chemotaxis(GO:2000510)
0.1 1.0 GO:0007220 Notch receptor processing(GO:0007220)
0.1 0.6 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.5 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.7 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 1.3 GO:0060746 parental behavior(GO:0060746)
0.1 5.2 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 0.3 GO:0072719 cellular response to cisplatin(GO:0072719)
0.1 1.1 GO:0048266 behavioral response to pain(GO:0048266)
0.1 3.0 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.1 1.8 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 0.6 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 0.6 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.7 GO:0006817 phosphate ion transport(GO:0006817)
0.1 0.4 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1 0.6 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.1 1.5 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 1.1 GO:0032757 positive regulation of interleukin-8 production(GO:0032757) positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
0.1 0.8 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.1 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.0 1.0 GO:2000505 regulation of energy homeostasis(GO:2000505)
0.0 1.3 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 1.9 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.5 GO:0090148 membrane fission(GO:0090148)
0.0 1.6 GO:0001709 cell fate determination(GO:0001709)
0.0 1.6 GO:0031648 protein destabilization(GO:0031648)
0.0 0.9 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.2 GO:0002667 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.0 0.4 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.7 GO:0060009 Sertoli cell development(GO:0060009)
0.0 2.7 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0010958 regulation of amino acid import(GO:0010958)
0.0 0.9 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0 0.3 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.9 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.0 0.9 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 1.2 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.7 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 1.6 GO:0007628 adult walking behavior(GO:0007628)
0.0 2.3 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.6 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 0.5 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 2.0 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.8 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 2.4 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.3 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.0 0.1 GO:0048069 eye pigmentation(GO:0048069) melanosome assembly(GO:1903232)
0.0 2.7 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.7 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 1.6 GO:0007286 spermatid development(GO:0007286)
0.0 1.9 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 0.2 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.6 GO:0045454 cell redox homeostasis(GO:0045454)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.5 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.5 1.4 GO:0005899 insulin receptor complex(GO:0005899)
0.3 3.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.3 2.9 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.3 0.8 GO:0005927 muscle tendon junction(GO:0005927)
0.3 1.0 GO:0031084 BLOC-2 complex(GO:0031084)
0.2 2.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.2 0.9 GO:0032280 symmetric synapse(GO:0032280)
0.2 3.6 GO:1990635 proximal dendrite(GO:1990635)
0.2 1.0 GO:0035189 Rb-E2F complex(GO:0035189)
0.2 0.6 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.2 0.9 GO:0031523 Myb complex(GO:0031523)
0.2 1.3 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 1.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 1.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 1.6 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.5 GO:0000346 transcription export complex(GO:0000346)
0.1 2.3 GO:0010369 chromocenter(GO:0010369)
0.1 0.6 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.1 3.5 GO:0090544 BAF-type complex(GO:0090544)
0.1 1.3 GO:0005869 dynactin complex(GO:0005869)
0.1 0.8 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 0.7 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 1.6 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 0.4 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.4 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 2.7 GO:0035861 site of double-strand break(GO:0035861)
0.1 0.4 GO:0045179 apical cortex(GO:0045179)
0.1 2.7 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 0.7 GO:0030056 hemidesmosome(GO:0030056)
0.1 2.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 2.3 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 0.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 1.6 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.5 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 14.4 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.6 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 2.5 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 1.9 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.3 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 1.0 GO:0031430 M band(GO:0031430)
0.0 0.8 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 1.2 GO:0032420 stereocilium(GO:0032420)
0.0 0.8 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.6 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.4 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.7 15.6 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.6 2.5 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.5 2.7 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.4 1.7 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.4 3.4 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.3 1.5 GO:0004594 pantothenate kinase activity(GO:0004594)
0.3 1.4 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.2 0.7 GO:0005436 sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319)
0.2 1.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.2 0.6 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.2 3.8 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.2 1.0 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.2 0.6 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.2 1.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 1.6 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 1.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.7 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.4 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.1 2.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.5 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.5 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.1 1.9 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 1.0 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 0.9 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 1.0 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 0.4 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.1 3.0 GO:0070064 proline-rich region binding(GO:0070064)
0.1 4.0 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.5 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.6 GO:0033592 RNA strand annealing activity(GO:0033592)
0.1 1.7 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.4 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 1.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 2.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 0.6 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 1.0 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 1.6 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 0.7 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 0.9 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.6 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.6 GO:0035615 clathrin heavy chain binding(GO:0032050) clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 1.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 1.5 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 1.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.5 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.3 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 1.0 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 1.5 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 1.7 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.0 1.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.9 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.0 1.2 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 10.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 1.4 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.3 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 7.0 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.5 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.9 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 1.6 GO:0044325 ion channel binding(GO:0044325)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 0.7 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 5.5 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 1.4 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.0 3.3 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.9 PID_FAS_PATHWAY FAS (CD95) signaling pathway
0.0 1.1 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 1.3 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.0 1.7 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.4 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.0 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 0.3 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.9 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.2 3.8 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.2 1.5 REACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS Genes involved in Acetylcholine Binding And Downstream Events
0.1 1.7 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 7.7 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 1.4 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.1 1.0 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 1.9 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 1.4 REACTOME_SOS_MEDIATED_SIGNALLING Genes involved in SOS-mediated signalling
0.1 1.3 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 2.5 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 0.2 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.5 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.9 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.0 0.9 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.0 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 1.0 REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.4 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.2 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.5 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.5 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.8 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.5 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.3 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production