Motif ID: Hmx2

Z-value: 0.623


Transcription factors associated with Hmx2:

Gene SymbolEntrez IDGene Name
Hmx2 ENSMUSG00000050100.7 Hmx2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hmx2mm10_v2_chr7_+_131548755_131548773-0.105.5e-01Click!


Activity profile for motif Hmx2.

activity profile for motif Hmx2


Sorted Z-values histogram for motif Hmx2

Sorted Z-values for motif Hmx2



Network of associatons between targets according to the STRING database.



First level regulatory network of Hmx2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_72441852 2.989 ENSMUST00000162159.1
Lrrc9
leucine rich repeat containing 9
chr6_-_137169710 2.531 ENSMUST00000117919.1
Rerg
RAS-like, estrogen-regulated, growth-inhibitor
chr6_-_137169678 2.310 ENSMUST00000119610.1
Rerg
RAS-like, estrogen-regulated, growth-inhibitor
chr5_-_131308076 2.084 ENSMUST00000160609.1
Wbscr17
Williams-Beuren syndrome chromosome region 17 homolog (human)
chr5_-_131307848 1.696 ENSMUST00000086023.5
Wbscr17
Williams-Beuren syndrome chromosome region 17 homolog (human)
chr12_+_52699297 1.518 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chr12_-_98901478 1.374 ENSMUST00000065716.6
Eml5
echinoderm microtubule associated protein like 5
chr3_+_109573907 1.312 ENSMUST00000106576.2
Vav3
vav 3 oncogene
chr15_-_42676967 1.290 ENSMUST00000022921.5
Angpt1
angiopoietin 1
chr9_-_75611308 1.232 ENSMUST00000064433.3
Tmod2
tropomodulin 2
chrM_+_7759 1.148 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr5_-_28210022 1.145 ENSMUST00000118882.1
Cnpy1
canopy 1 homolog (zebrafish)
chr9_+_86485407 1.143 ENSMUST00000034987.8
Dopey1
dopey family member 1
chr18_-_34579072 1.107 ENSMUST00000079287.5
Nme5
NME/NM23 family member 5
chr8_+_90828820 1.090 ENSMUST00000109614.2
ENSMUST00000048665.6
Chd9

chromodomain helicase DNA binding protein 9

chr9_-_50739365 1.049 ENSMUST00000117093.1
ENSMUST00000121634.1
Dixdc1

DIX domain containing 1

chr9_-_37552904 1.010 ENSMUST00000065668.5
Nrgn
neurogranin
chr10_+_69925766 0.997 ENSMUST00000182269.1
ENSMUST00000183261.1
ENSMUST00000183074.1
Ank3


ankyrin 3, epithelial


chr9_-_54501496 0.983 ENSMUST00000118600.1
ENSMUST00000118163.1
Dmxl2

Dmx-like 2

chr18_+_62977826 0.957 ENSMUST00000025474.6
Napg
N-ethylmaleimide sensitive fusion protein attachment protein gamma
chr19_-_46969474 0.881 ENSMUST00000086961.7
Nt5c2
5'-nucleotidase, cytosolic II
chr4_-_45532470 0.876 ENSMUST00000147448.1
Shb
src homology 2 domain-containing transforming protein B
chr10_+_69925800 0.830 ENSMUST00000182029.1
Ank3
ankyrin 3, epithelial
chr4_+_90218820 0.827 ENSMUST00000107129.1
Zfp352
zinc finger protein 352
chr4_-_26346882 0.826 ENSMUST00000041374.7
ENSMUST00000153813.1
Manea

mannosidase, endo-alpha

chr18_-_31911903 0.823 ENSMUST00000054984.6
Sft2d3
SFT2 domain containing 3
chr6_+_134640940 0.816 ENSMUST00000062755.8
Loh12cr1
loss of heterozygosity, 12, chromosomal region 1 homolog (human)
chr5_+_8660059 0.816 ENSMUST00000047753.4
Abcb1a
ATP-binding cassette, sub-family B (MDR/TAP), member 1A
chr18_+_62977854 0.815 ENSMUST00000150267.1
Napg
N-ethylmaleimide sensitive fusion protein attachment protein gamma
chr8_-_54724474 0.807 ENSMUST00000175915.1
Wdr17
WD repeat domain 17
chr2_-_33087169 0.792 ENSMUST00000102810.3
Garnl3
GTPase activating RANGAP domain-like 3
chr1_-_172632931 0.783 ENSMUST00000027826.5
Dusp23
dual specificity phosphatase 23
chr19_-_58454435 0.715 ENSMUST00000169850.1
Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chrX_-_75578188 0.687 ENSMUST00000033545.5
Rab39b
RAB39B, member RAS oncogene family
chr3_+_124321031 0.675 ENSMUST00000058994.4
Tram1l1
translocation associated membrane protein 1-like 1
chr10_-_81001338 0.666 ENSMUST00000099462.1
ENSMUST00000118233.1
Gng7

guanine nucleotide binding protein (G protein), gamma 7

chr19_-_40402267 0.636 ENSMUST00000099467.3
ENSMUST00000099466.3
ENSMUST00000165212.1
ENSMUST00000165469.1
Sorbs1



sorbin and SH3 domain containing 1



chr10_+_24869998 0.627 ENSMUST00000020159.8
Med23
mediator complex subunit 23
chr4_-_96553617 0.623 ENSMUST00000030303.5
Cyp2j6
cytochrome P450, family 2, subfamily j, polypeptide 6
chr1_+_46066738 0.620 ENSMUST00000069293.7
Dnah7b
dynein, axonemal, heavy chain 7B
chr8_+_71922810 0.617 ENSMUST00000119003.1
Zfp617
zinc finger protein 617
chrX_+_112615301 0.609 ENSMUST00000122805.1
Zfp711
zinc finger protein 711
chr19_+_29367447 0.579 ENSMUST00000016640.7
Cd274
CD274 antigen
chr19_-_29367294 0.566 ENSMUST00000138051.1
Plgrkt
plasminogen receptor, C-terminal lysine transmembrane protein
chr2_-_45112890 0.552 ENSMUST00000076836.6
Zeb2
zinc finger E-box binding homeobox 2
chr18_+_37819543 0.540 ENSMUST00000055935.5
Pcdhga9
protocadherin gamma subfamily A, 9
chr5_-_73256555 0.537 ENSMUST00000101127.5
ENSMUST00000171179.1
Fryl
Fryl
furry homolog-like (Drosophila)
furry homolog-like (Drosophila)
chr9_-_15301555 0.526 ENSMUST00000034414.8
4931406C07Rik
RIKEN cDNA 4931406C07 gene
chr9_-_122310921 0.524 ENSMUST00000180685.1
Gm26797
predicted gene, 26797
chr5_+_144100387 0.508 ENSMUST00000041804.7
Lmtk2
lemur tyrosine kinase 2
chr14_-_52213379 0.505 ENSMUST00000140603.1
Chd8
chromodomain helicase DNA binding protein 8
chr2_+_167421706 0.503 ENSMUST00000047815.6
ENSMUST00000109218.1
ENSMUST00000073873.3
Slc9a8


solute carrier family 9 (sodium/hydrogen exchanger), member 8


chr2_+_30982350 0.499 ENSMUST00000061544.4
ENSMUST00000138161.1
ENSMUST00000142232.1
Usp20


ubiquitin specific peptidase 20


chr2_-_33086366 0.494 ENSMUST00000049618.2
Garnl3
GTPase activating RANGAP domain-like 3
chr3_+_106721672 0.490 ENSMUST00000098750.2
ENSMUST00000130105.1
Lrif1

ligand dependent nuclear receptor interacting factor 1

chr1_-_57970067 0.486 ENSMUST00000164963.1
Kctd18
potassium channel tetramerisation domain containing 18
chr1_-_57970104 0.486 ENSMUST00000114410.3
Kctd18
potassium channel tetramerisation domain containing 18
chr10_+_116143881 0.484 ENSMUST00000105271.2
Ptprr
protein tyrosine phosphatase, receptor type, R
chr2_+_83644435 0.478 ENSMUST00000081591.6
Zc3h15
zinc finger CCCH-type containing 15
chr8_+_25808474 0.478 ENSMUST00000033979.4
Star
steroidogenic acute regulatory protein
chr9_-_20728219 0.475 ENSMUST00000034692.7
Olfm2
olfactomedin 2
chr8_-_22694061 0.469 ENSMUST00000131767.1
Ikbkb
inhibitor of kappaB kinase beta
chr7_-_37772868 0.466 ENSMUST00000176205.1
Zfp536
zinc finger protein 536
chr11_-_96977660 0.464 ENSMUST00000107626.1
ENSMUST00000107624.1
Sp2

Sp2 transcription factor

chr12_-_101913116 0.459 ENSMUST00000177536.1
ENSMUST00000176728.1
ENSMUST00000021605.7
Trip11


thyroid hormone receptor interactor 11


chr2_+_30392405 0.457 ENSMUST00000113612.3
ENSMUST00000123202.1
Dolpp1

dolichyl pyrophosphate phosphatase 1

chr11_-_106612928 0.451 ENSMUST00000042780.7
Tex2
testis expressed gene 2
chr5_-_20951769 0.449 ENSMUST00000036489.5
Rsbn1l
round spermatid basic protein 1-like
chr13_+_83732438 0.442 ENSMUST00000182701.1
C130071C03Rik
RIKEN cDNA C130071C03 gene
chr2_-_156992021 0.440 ENSMUST00000109558.1
ENSMUST00000069600.6
ENSMUST00000072298.6
Ndrg3


N-myc downstream regulated gene 3


chrX_+_38600626 0.422 ENSMUST00000000365.2
Mcts1
malignant T cell amplified sequence 1
chr5_-_31526693 0.400 ENSMUST00000118874.1
ENSMUST00000117642.1
ENSMUST00000065388.4
Supt7l


suppressor of Ty 7-like


chr3_-_116712644 0.392 ENSMUST00000029569.2
Slc35a3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr4_-_94603239 0.386 ENSMUST00000107107.2
Plaa
phospholipase A2, activating protein
chr5_-_28210168 0.369 ENSMUST00000117098.1
Cnpy1
canopy 1 homolog (zebrafish)
chr17_-_53539411 0.355 ENSMUST00000056198.3
Pp2d1
protein phosphatase 2C-like domain containing 1
chr14_+_48446340 0.351 ENSMUST00000111735.2
Tmem260
transmembrane protein 260
chr3_+_10088173 0.345 ENSMUST00000061419.7
Gm9833
predicted gene 9833
chr8_+_25017211 0.344 ENSMUST00000033961.5
Tm2d2
TM2 domain containing 2
chr3_-_87748619 0.335 ENSMUST00000023846.4
Lrrc71
leucine rich repeat containing 71
chr14_+_48446128 0.327 ENSMUST00000124720.1
Tmem260
transmembrane protein 260
chr10_+_128908907 0.327 ENSMUST00000105229.1
Cd63
CD63 antigen
chr4_-_132398199 0.313 ENSMUST00000136711.1
ENSMUST00000084249.4
Phactr4

phosphatase and actin regulator 4

chr10_+_121365078 0.311 ENSMUST00000040344.6
Gns
glucosamine (N-acetyl)-6-sulfatase
chr18_+_6765171 0.308 ENSMUST00000097680.5
Rab18
RAB18, member RAS oncogene family
chr1_+_109993982 0.297 ENSMUST00000027542.6
Cdh7
cadherin 7, type 2
chr16_+_17619341 0.280 ENSMUST00000006053.6
ENSMUST00000171435.1
ENSMUST00000163476.1
ENSMUST00000168101.1
ENSMUST00000165363.1
ENSMUST00000169662.1
ENSMUST00000090159.4
ENSMUST00000172182.1
ENSMUST00000163592.1
Smpd4








sphingomyelin phosphodiesterase 4








chr17_+_48346465 0.278 ENSMUST00000113237.3
Trem2
triggering receptor expressed on myeloid cells 2
chr6_-_113501818 0.276 ENSMUST00000101059.1
Prrt3
proline-rich transmembrane protein 3
chr13_-_107022027 0.274 ENSMUST00000117539.1
ENSMUST00000122233.1
ENSMUST00000022204.9
ENSMUST00000159772.1
Kif2a



kinesin family member 2A



chr14_-_104522615 0.271 ENSMUST00000022716.2
Rnf219
ring finger protein 219
chr3_+_95217417 0.270 ENSMUST00000181819.1
Gm16740
predicted gene, 16740
chr7_+_3645267 0.258 ENSMUST00000038913.9
Cnot3
CCR4-NOT transcription complex, subunit 3
chr16_+_36934976 0.255 ENSMUST00000023531.8
Hcls1
hematopoietic cell specific Lyn substrate 1
chr3_-_65392546 0.239 ENSMUST00000119896.1
Ssr3
signal sequence receptor, gamma
chrX_-_56598069 0.239 ENSMUST00000059899.2
Mmgt1
membrane magnesium transporter 1
chr5_+_29195983 0.238 ENSMUST00000160888.1
ENSMUST00000159272.1
ENSMUST00000001247.5
ENSMUST00000161398.1
ENSMUST00000160246.1
Rnf32




ring finger protein 32




chr2_-_127444524 0.218 ENSMUST00000028848.3
Fahd2a
fumarylacetoacetate hydrolase domain containing 2A
chrX_+_140367494 0.212 ENSMUST00000141660.1
Frmpd3
FERM and PDZ domain containing 3
chr2_-_164071089 0.208 ENSMUST00000018466.3
Tomm34
translocase of outer mitochondrial membrane 34
chr10_+_79910856 0.207 ENSMUST00000181321.1
Gm26602
predicted gene, 26602
chr16_-_14291355 0.206 ENSMUST00000090287.3
Myh11
myosin, heavy polypeptide 11, smooth muscle
chr7_-_133123770 0.202 ENSMUST00000164896.1
ENSMUST00000171968.1
Ctbp2

C-terminal binding protein 2

chr2_-_164071124 0.197 ENSMUST00000109384.3
Tomm34
translocase of outer mitochondrial membrane 34
chr12_+_84451485 0.189 ENSMUST00000137170.1
Lin52
lin-52 homolog (C. elegans)
chr4_-_15149755 0.172 ENSMUST00000108273.1
Necab1
N-terminal EF-hand calcium binding protein 1
chr1_-_75142360 0.172 ENSMUST00000041213.5
Cnppd1
cyclin Pas1/PHO80 domain containing 1
chr5_-_114380459 0.166 ENSMUST00000001125.5
Kctd10
potassium channel tetramerisation domain containing 10
chr12_+_8973892 0.165 ENSMUST00000085745.6
ENSMUST00000111113.2
Wdr35

WD repeat domain 35

chr11_-_78080360 0.164 ENSMUST00000021183.3
Eral1
Era (G-protein)-like 1 (E. coli)
chr1_+_173420567 0.153 ENSMUST00000173023.1
Aim2
absent in melanoma 2
chrX_-_164027965 0.150 ENSMUST00000033739.4
Car5b
carbonic anhydrase 5b, mitochondrial
chr2_-_9878580 0.148 ENSMUST00000102976.3
Gata3
GATA binding protein 3
chr8_-_8690493 0.143 ENSMUST00000048545.8
Arglu1
arginine and glutamate rich 1
chr7_-_43505926 0.137 ENSMUST00000013497.1
ENSMUST00000163619.1
4931406B18Rik

RIKEN cDNA 4931406B18 gene

chr7_-_133123409 0.135 ENSMUST00000170459.1
ENSMUST00000166400.1
Ctbp2

C-terminal binding protein 2

chr5_+_114380591 0.131 ENSMUST00000074002.5
Ube3b
ubiquitin protein ligase E3B
chr14_-_18893376 0.131 ENSMUST00000151926.1
Ube2e2
ubiquitin-conjugating enzyme E2E 2
chr15_+_85510812 0.123 ENSMUST00000079690.2
Gm4825
predicted pseudogene 4825
chr17_+_35841668 0.123 ENSMUST00000174124.1
Mdc1
mediator of DNA damage checkpoint 1
chr3_+_66985947 0.122 ENSMUST00000161726.1
ENSMUST00000160504.1
Rsrc1

arginine/serine-rich coiled-coil 1

chr9_-_113708209 0.118 ENSMUST00000111861.3
ENSMUST00000035086.6
Pdcd6ip

programmed cell death 6 interacting protein

chr1_-_180813534 0.116 ENSMUST00000159789.1
ENSMUST00000081026.4
H3f3a

H3 histone, family 3A

chr2_-_75938407 0.114 ENSMUST00000099996.3
Ttc30b
tetratricopeptide repeat domain 30B
chr4_+_124880899 0.104 ENSMUST00000059343.6
Epha10
Eph receptor A10
chr11_-_115933464 0.101 ENSMUST00000021097.3
Recql5
RecQ protein-like 5
chr3_+_19957037 0.097 ENSMUST00000091309.5
ENSMUST00000108329.1
ENSMUST00000003714.6
Cp


ceruloplasmin


chr3_-_65392579 0.094 ENSMUST00000029414.5
Ssr3
signal sequence receptor, gamma
chr8_-_110902442 0.093 ENSMUST00000041382.6
Fuk
fucokinase
chr1_+_91298354 0.086 ENSMUST00000142488.1
ENSMUST00000124832.1
ENSMUST00000147523.1
Scly


selenocysteine lyase


chr17_-_34628380 0.069 ENSMUST00000167097.2
Ppt2
palmitoyl-protein thioesterase 2
chr5_-_114380505 0.057 ENSMUST00000102581.4
Kctd10
potassium channel tetramerisation domain containing 10
chr1_-_37536232 0.046 ENSMUST00000042161.8
Mgat4a
mannoside acetylglucosaminyltransferase 4, isoenzyme A
chr1_+_164275559 0.045 ENSMUST00000027867.6
Ccdc181
coiled-coil domain containing 181
chr5_+_8893677 0.037 ENSMUST00000003717.8
Abcb4
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr8_+_34054622 0.035 ENSMUST00000149618.1
Gm9951
predicted gene 9951
chr11_-_3931960 0.033 ENSMUST00000109990.1
ENSMUST00000020710.4
ENSMUST00000109989.3
ENSMUST00000109991.1
ENSMUST00000109993.2
Tcn2




transcobalamin 2




chr4_+_94739276 0.024 ENSMUST00000073939.6
ENSMUST00000102798.1
Tek

endothelial-specific receptor tyrosine kinase

chr4_-_56947411 0.005 ENSMUST00000107609.3
ENSMUST00000068792.6
Tmem245

transmembrane protein 245

chr14_-_48667508 0.004 ENSMUST00000144465.1
ENSMUST00000133479.1
ENSMUST00000119070.1
ENSMUST00000152018.1
Otx2



orthodenticle homolog 2 (Drosophila)




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0048014 Tie signaling pathway(GO:0048014)
0.4 1.5 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.2 0.6 GO:2000409 positive regulation of T cell extravasation(GO:2000409)
0.2 0.6 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.2 1.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.2 0.8 GO:0046618 drug export(GO:0046618)
0.2 1.8 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.6 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.1 0.3 GO:0002586 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.1 0.5 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 0.5 GO:0070859 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.1 0.7 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 1.0 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.4 GO:0002188 translation reinitiation(GO:0002188)
0.1 1.1 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 0.9 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.6 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.1 0.5 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 0.6 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.1 0.9 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 1.0 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 0.4 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.1 0.3 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 1.1 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 0.3 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.1 0.6 GO:0036159 inner dynein arm assembly(GO:0036159)
0.1 0.4 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.1 0.5 GO:0090527 actin filament reorganization(GO:0090527)
0.1 1.3 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.1 GO:0035799 ureter maturation(GO:0035799) cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536) regulation of T-helper 2 cell cytokine production(GO:2000551) positive regulation of T-helper 2 cell cytokine production(GO:2000553)
0.0 1.1 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.5 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.3 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.1 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.2 GO:0070269 pyroptosis(GO:0070269)
0.0 0.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.5 GO:0033572 transferrin transport(GO:0033572)
0.0 0.5 GO:0003413 chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413)
0.0 0.4 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.5 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:1902340 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.0 1.0 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
0.0 0.2 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.1 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.3 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.1 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.0 0.3 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.6 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 0.1 GO:0001887 selenium compound metabolic process(GO:0001887) selenocysteine metabolic process(GO:0016259)
0.0 0.5 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.4 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 3.6 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 0.3 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0005899 insulin receptor complex(GO:0005899)
0.2 0.6 GO:0036156 inner dynein arm(GO:0036156)
0.1 0.9 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 1.8 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 1.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 1.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.3 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.1 1.0 GO:0044327 dendritic spine head(GO:0044327)
0.0 1.2 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0061702 inflammasome complex(GO:0061702)
0.0 0.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.5 GO:0030061 mitochondrial crista(GO:0030061)
0.0 1.8 GO:0031201 SNARE complex(GO:0031201)
0.0 0.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.5 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.4 GO:0030914 STAGA complex(GO:0030914)
0.0 0.3 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 1.3 GO:0005902 microvillus(GO:0005902)
0.0 0.5 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 1.4 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.2 GO:0036038 MKS complex(GO:0036038)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)
0.0 0.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0090543 Flemming body(GO:0090543)
0.0 0.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.2 0.6 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.2 0.9 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559) phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.2 0.5 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 1.2 GO:0005523 tropomyosin binding(GO:0005523)
0.1 1.5 GO:0043495 protein anchor(GO:0043495)
0.1 1.3 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 0.3 GO:0070891 peptidoglycan binding(GO:0042834) lipoteichoic acid binding(GO:0070891)
0.1 0.5 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 0.3 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 1.1 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 0.9 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.8 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.1 1.0 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.6 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.3 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 1.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 1.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.4 GO:0016004 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.0 1.8 GO:0030507 spectrin binding(GO:0030507)
0.0 1.0 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0015087 cobalt ion transmembrane transporter activity(GO:0015087)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.7 GO:0031489 myosin V binding(GO:0031489)
0.0 0.5 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.1 GO:0070279 vitamin B6 binding(GO:0070279)
0.0 0.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 5.1 GO:0003924 GTPase activity(GO:0003924)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.4 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 0.1 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.8 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.6 GO:0070412 R-SMAD binding(GO:0070412)
0.0 1.1 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.5 GO:0017022 myosin binding(GO:0017022)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.5 GO:0042974 retinoic acid receptor binding(GO:0042974)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.0 0.9 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.0 0.5 PID_NFKAPPAB_ATYPICAL_PATHWAY Atypical NF-kappaB pathway
0.0 1.3 PID_SHP2_PATHWAY SHP2 signaling
0.0 0.7 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.6 PID_INSULIN_PATHWAY Insulin Pathway
0.0 1.4 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.4 PID_MYC_PATHWAY C-MYC pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.8 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.1 0.9 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.1 0.6 REACTOME_PD1_SIGNALING Genes involved in PD-1 signaling
0.1 1.3 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.1 1.8 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.5 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.0 1.3 REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.3 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.5 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.7 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.8 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.7 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.6 REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.3 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.3 REACTOME_KINESINS Genes involved in Kinesins