Motif ID: Hoxa2

Z-value: 0.998


Transcription factors associated with Hoxa2:

Gene SymbolEntrez IDGene Name
Hoxa2 ENSMUSG00000014704.8 Hoxa2



Activity profile for motif Hoxa2.

activity profile for motif Hoxa2


Sorted Z-values histogram for motif Hoxa2

Sorted Z-values for motif Hoxa2



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_139543889 12.633 ENSMUST00000174792.1
ENSMUST00000031523.8
Uncx

UNC homeobox

chr2_-_117342949 7.563 ENSMUST00000102534.4
Rasgrp1
RAS guanyl releasing protein 1
chr2_-_117342831 7.190 ENSMUST00000178884.1
Rasgrp1
RAS guanyl releasing protein 1
chr12_+_109747903 6.981 ENSMUST00000183084.1
ENSMUST00000182300.1
Mirg

miRNA containing gene

chr2_-_117342709 6.974 ENSMUST00000173541.1
ENSMUST00000172901.1
ENSMUST00000173252.1
Rasgrp1


RAS guanyl releasing protein 1


chr14_-_34374617 6.075 ENSMUST00000023826.4
Sncg
synuclein, gamma
chr8_-_4779513 4.629 ENSMUST00000022945.7
Shcbp1
Shc SH2-domain binding protein 1
chr3_+_55782500 4.341 ENSMUST00000075422.4
Mab21l1
mab-21-like 1 (C. elegans)
chr10_-_26078987 3.929 ENSMUST00000066049.6
Tmem200a
transmembrane protein 200A
chr7_+_45163915 3.888 ENSMUST00000085374.5
Slc17a7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr11_-_58801944 3.397 ENSMUST00000094156.4
ENSMUST00000060581.3
Fam183b

family with sequence similarity 183, member B

chr8_-_87959560 3.392 ENSMUST00000109655.2
Zfp423
zinc finger protein 423
chr9_-_106158109 3.374 ENSMUST00000159809.1
ENSMUST00000162562.1
ENSMUST00000036382.6
ENSMUST00000112543.2
Glyctk



glycerate kinase



chr1_-_133907053 3.241 ENSMUST00000149380.1
ENSMUST00000124051.2
Optc

opticin

chr9_-_73968901 3.166 ENSMUST00000184666.1
Unc13c
unc-13 homolog C (C. elegans)
chr17_-_53539411 2.951 ENSMUST00000056198.3
Pp2d1
protein phosphatase 2C-like domain containing 1
chr16_-_23890805 2.929 ENSMUST00000004480.3
Sst
somatostatin
chrX_-_103483205 2.925 ENSMUST00000127786.2
Xist
inactive X specific transcripts
chr10_-_92162753 2.880 ENSMUST00000182197.1
Rmst
rhabdomyosarcoma 2 associated transcript (non-coding RNA)
chr1_-_133906973 2.829 ENSMUST00000126123.1
Optc
opticin
chr5_+_24985840 2.734 ENSMUST00000075081.6
1500035N22Rik
RIKEN cDNA 1500035N22 gene
chr8_-_105471481 2.685 ENSMUST00000014990.6
Tppp3
tubulin polymerization-promoting protein family member 3
chr6_+_5390387 2.562 ENSMUST00000183358.1
Asb4
ankyrin repeat and SOCS box-containing 4
chr9_+_51621425 2.397 ENSMUST00000089534.4
Gm7293
predicted gene 7293
chr12_+_44328882 2.380 ENSMUST00000020939.8
ENSMUST00000110748.2
Nrcam

neuron-glia-CAM-related cell adhesion molecule

chr15_-_81729864 2.373 ENSMUST00000171115.1
ENSMUST00000170134.1
ENSMUST00000052374.5
Rangap1


RAN GTPase activating protein 1


chr5_-_24527276 2.358 ENSMUST00000088311.4
Gbx1
gastrulation brain homeobox 1
chr15_-_84447037 2.332 ENSMUST00000080751.2
1810041L15Rik
RIKEN cDNA 1810041L15 gene
chr8_-_110902442 2.287 ENSMUST00000041382.6
Fuk
fucokinase
chr6_+_14901344 2.283 ENSMUST00000115477.1
Foxp2
forkhead box P2
chr13_+_117220584 2.267 ENSMUST00000022242.7
Emb
embigin
chr2_-_69206133 2.253 ENSMUST00000112320.1
Spc25
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr5_-_30945393 2.220 ENSMUST00000031051.6
Cgref1
cell growth regulator with EF hand domain 1
chr4_+_116596672 2.185 ENSMUST00000051869.7
Ccdc17
coiled-coil domain containing 17
chr3_-_116253467 2.058 ENSMUST00000090473.5
Gpr88
G-protein coupled receptor 88
chr15_+_59648350 2.058 ENSMUST00000067543.6
Trib1
tribbles homolog 1 (Drosophila)
chr9_-_21760275 2.043 ENSMUST00000098942.4
Spc24
SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr3_+_134828993 2.021 ENSMUST00000029822.4
Tacr3
tachykinin receptor 3
chr19_+_24875679 2.017 ENSMUST00000073080.5
Gm10053
predicted gene 10053
chrX_+_96455359 1.968 ENSMUST00000033553.7
Heph
hephaestin
chr19_-_41743665 1.940 ENSMUST00000025993.3
Slit1
slit homolog 1 (Drosophila)
chr7_+_100537192 1.924 ENSMUST00000120454.1
Coa4
cytochrome c oxidase assembly factor 4
chr6_+_83156401 1.921 ENSMUST00000032106.4
1700003E16Rik
RIKEN cDNA 1700003E16 gene
chr5_+_115235836 1.917 ENSMUST00000081497.6
Pop5
processing of precursor 5, ribonuclease P/MRP family (S. cerevisiae)
chr4_+_15881255 1.913 ENSMUST00000029876.1
Calb1
calbindin 1
chr4_-_35157404 1.911 ENSMUST00000102975.3
Mob3b
MOB kinase activator 3B
chr3_+_124321031 1.903 ENSMUST00000058994.4
Tram1l1
translocation associated membrane protein 1-like 1
chr10_-_96409038 1.887 ENSMUST00000179683.1
Gm20091
predicted gene, 20091
chr11_-_106998483 1.881 ENSMUST00000124541.1
Kpna2
karyopherin (importin) alpha 2
chr2_-_69206146 1.848 ENSMUST00000127243.1
ENSMUST00000149643.1
ENSMUST00000167875.2
ENSMUST00000005365.8
Spc25



SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)



chr19_-_10203880 1.847 ENSMUST00000142241.1
ENSMUST00000116542.2
ENSMUST00000025651.5
ENSMUST00000156291.1
Fen1



flap structure specific endonuclease 1



chr2_+_103957976 1.807 ENSMUST00000156813.1
ENSMUST00000170926.1
Lmo2

LIM domain only 2

chr4_+_46450892 1.798 ENSMUST00000102926.4
Anp32b
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr7_+_144838590 1.723 ENSMUST00000105898.1
Fgf3
fibroblast growth factor 3
chr4_-_92191749 1.687 ENSMUST00000123179.1
Gm12666
predicted gene 12666
chr11_-_100356116 1.667 ENSMUST00000138603.2
Hap1
huntingtin-associated protein 1
chr2_-_84775388 1.615 ENSMUST00000023994.3
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr3_-_107931817 1.611 ENSMUST00000004137.4
Gstm7
glutathione S-transferase, mu 7
chr4_+_105790534 1.597 ENSMUST00000185012.1
Gm12728
predicted gene 12728
chr4_+_95557494 1.597 ENSMUST00000079223.4
ENSMUST00000177394.1
Fggy

FGGY carbohydrate kinase domain containing

chr2_+_174285352 1.568 ENSMUST00000130761.1
Gnas
GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
chr8_+_83389846 1.541 ENSMUST00000002259.6
Clgn
calmegin
chr2_-_84775420 1.478 ENSMUST00000111641.1
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr10_-_63421739 1.455 ENSMUST00000054760.4
Gm7075
predicted gene 7075
chr3_-_37125943 1.432 ENSMUST00000029275.5
Il2
interleukin 2
chr7_+_142460834 1.428 ENSMUST00000018963.4
ENSMUST00000105967.1
Lsp1

lymphocyte specific 1

chr9_-_71485893 1.395 ENSMUST00000034720.5
Polr2m
polymerase (RNA) II (DNA directed) polypeptide M
chr11_-_68927049 1.392 ENSMUST00000038932.7
Odf4
outer dense fiber of sperm tails 4
chr5_-_130024280 1.382 ENSMUST00000161640.1
ENSMUST00000161884.1
ENSMUST00000161094.1
Asl


argininosuccinate lyase


chr9_+_104569671 1.376 ENSMUST00000057742.8
Cpne4
copine IV
chr5_+_92683625 1.374 ENSMUST00000168878.1
Shroom3
shroom family member 3
chr7_+_100495987 1.373 ENSMUST00000133044.1
Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr7_+_73391160 1.369 ENSMUST00000128471.1
Rgma
RGM domain family, member A
chrM_+_7759 1.363 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr17_+_34135182 1.362 ENSMUST00000042121.9
H2-DMa
histocompatibility 2, class II, locus DMa
chr10_-_95673451 1.344 ENSMUST00000099328.1
Anapc15-ps
anaphase prompoting complex C subunit 15, pseudogene
chr17_-_71310952 1.331 ENSMUST00000024849.9
Emilin2
elastin microfibril interfacer 2
chr3_-_92429403 1.314 ENSMUST00000047300.7
Gm9774
predicted pseudogene 9774
chr14_+_11227511 1.308 ENSMUST00000080237.3
Rpl21-ps4
ribosomal protein L21, pseudogene 4
chr15_-_78773452 1.306 ENSMUST00000018313.5
Mfng
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr4_-_43653542 1.302 ENSMUST00000084646.4
Spag8
sperm associated antigen 8
chr17_-_32166879 1.300 ENSMUST00000087723.3
Notch3
notch 3
chr14_-_61037937 1.278 ENSMUST00000111236.2
Tnfrsf19
tumor necrosis factor receptor superfamily, member 19
chr3_+_85915722 1.275 ENSMUST00000054148.7
Gm9790
predicted gene 9790
chr11_-_100356078 1.269 ENSMUST00000103124.4
Hap1
huntingtin-associated protein 1
chr3_-_157925056 1.265 ENSMUST00000118539.1
Cth
cystathionase (cystathionine gamma-lyase)
chr9_+_122951051 1.257 ENSMUST00000040717.5
Kif15
kinesin family member 15
chr2_-_149798701 1.255 ENSMUST00000148202.1
ENSMUST00000139471.1
Gm14133

predicted gene 14133

chr14_+_58070547 1.243 ENSMUST00000165526.1
Fgf9
fibroblast growth factor 9
chr13_+_23575753 1.234 ENSMUST00000105105.1
Hist1h3d
histone cluster 1, H3d
chr12_-_15816762 1.231 ENSMUST00000020922.7
Trib2
tribbles homolog 2 (Drosophila)
chr1_-_9700209 1.230 ENSMUST00000088658.4
Mybl1
myeloblastosis oncogene-like 1
chr5_+_115908644 1.203 ENSMUST00000141101.1
Cit
citron
chr11_-_78984831 1.203 ENSMUST00000073001.4
ENSMUST00000108269.3
Lgals9

lectin, galactose binding, soluble 9

chrX_+_8892376 1.195 ENSMUST00000064196.3
B630019K06Rik
RIKEN cDNA B630019K06 gene
chr15_+_79030874 1.189 ENSMUST00000171999.1
ENSMUST00000006544.7
Gcat

glycine C-acetyltransferase (2-amino-3-ketobutyrate-coenzyme A ligase)

chr4_-_83285141 1.184 ENSMUST00000150522.1
Ttc39b
tetratricopeptide repeat domain 39B
chr9_+_104569754 1.172 ENSMUST00000077190.6
Cpne4
copine IV
chr4_+_134510999 1.151 ENSMUST00000105866.2
Aunip
aurora kinase A and ninein interacting protein
chr12_+_87443896 1.148 ENSMUST00000161023.1
ENSMUST00000160488.1
ENSMUST00000077462.7
ENSMUST00000160880.1
Slirp



SRA stem-loop interacting RNA binding protein



chr15_-_55548164 1.143 ENSMUST00000165356.1
Mrpl13
mitochondrial ribosomal protein L13
chr3_+_32708546 1.141 ENSMUST00000029214.7
Actl6a
actin-like 6A
chr12_-_32061221 1.124 ENSMUST00000003079.5
ENSMUST00000036497.9
Prkar2b

protein kinase, cAMP dependent regulatory, type II beta

chr2_+_181763315 1.111 ENSMUST00000081125.4
Myt1
myelin transcription factor 1
chr9_-_14782964 1.107 ENSMUST00000034406.3
Ankrd49
ankyrin repeat domain 49
chr18_-_20682963 1.089 ENSMUST00000165229.2
Gm10269
predicted gene 10269
chr9_+_121710389 1.075 ENSMUST00000035113.9
Deb1
differentially expressed in B16F10 1
chr2_-_126709567 1.055 ENSMUST00000099423.2
Gm10774
predicted pseudogene 10774
chr10_-_128804353 1.040 ENSMUST00000051011.7
Tmem198b
transmembrane protein 198b
chr14_+_53665912 1.037 ENSMUST00000181768.1
Trav3-3
T cell receptor alpha variable 3-3
chr7_+_27473761 1.033 ENSMUST00000068641.6
Sertad3
SERTA domain containing 3
chrX_-_102157065 1.033 ENSMUST00000056904.2
Ercc6l
excision repair cross-complementing rodent repair deficiency complementation group 6 like
chr19_+_23723279 1.030 ENSMUST00000067077.1
Gm9938
predicted gene 9938
chr11_+_108682602 1.029 ENSMUST00000106718.3
ENSMUST00000106715.1
ENSMUST00000106724.3
Cep112


centrosomal protein 112


chr16_+_38346986 1.027 ENSMUST00000050273.8
ENSMUST00000120495.1
ENSMUST00000119704.1
Cox17

Gm21987
cytochrome c oxidase assembly protein 17

predicted gene 21987
chr7_-_27985796 1.023 ENSMUST00000099111.3
Zfp850
zinc finger protein 850
chr4_-_141606011 1.017 ENSMUST00000123150.1
ENSMUST00000133874.1
ENSMUST00000136831.1
ENSMUST00000130181.1
ENSMUST00000105785.2
Fblim1




filamin binding LIM protein 1




chr17_+_78491549 1.007 ENSMUST00000079363.4
Gm10093
predicted pseudogene 10093
chr6_+_142413441 1.007 ENSMUST00000088263.4
B230216G23Rik
RIKEN cDNA B230216G23 gene
chr5_+_138363719 1.003 ENSMUST00000100526.2
Gm10874
predicted gene 10874
chr3_-_58525867 0.998 ENSMUST00000029385.7
Serp1
stress-associated endoplasmic reticulum protein 1
chr17_+_46496753 0.985 ENSMUST00000046497.6
Dnph1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr11_-_78984946 0.982 ENSMUST00000108268.3
Lgals9
lectin, galactose binding, soluble 9
chr5_-_98566762 0.982 ENSMUST00000086912.4
1700010H22Rik
RIKEN cDNA 1700010H22 gene
chr15_-_102350692 0.981 ENSMUST00000041208.7
Aaas
achalasia, adrenocortical insufficiency, alacrimia
chr5_+_30281377 0.976 ENSMUST00000101448.3
Drc1
dynein regulatory complex subunit 1
chr8_+_123411424 0.972 ENSMUST00000071134.3
Tubb3
tubulin, beta 3 class III
chr9_+_58129476 0.970 ENSMUST00000133287.1
Stra6
stimulated by retinoic acid gene 6
chr1_-_175688353 0.969 ENSMUST00000104984.1
Chml
choroideremia-like
chr2_+_174285256 0.958 ENSMUST00000130940.1
Gnas
GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
chr15_+_39006272 0.957 ENSMUST00000179165.1
ENSMUST00000022906.7
Fzd6

frizzled homolog 6 (Drosophila)

chr3_-_107943362 0.956 ENSMUST00000106683.1
Gstm6
glutathione S-transferase, mu 6
chr12_-_87233556 0.955 ENSMUST00000021423.7
Noxred1
NADP+ dependent oxidoreductase domain containing 1
chr17_+_66123520 0.944 ENSMUST00000163605.2
Ddx11
DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
chr9_-_70141484 0.930 ENSMUST00000034749.8
Fam81a
family with sequence similarity 81, member A
chr14_-_13961202 0.918 ENSMUST00000065865.8
Thoc7
THO complex 7 homolog (Drosophila)
chrX_+_12587791 0.912 ENSMUST00000033313.2
Atp6ap2
ATPase, H+ transporting, lysosomal accessory protein 2
chr17_+_80290206 0.910 ENSMUST00000061703.9
Morn2
MORN repeat containing 2
chr16_+_92498122 0.910 ENSMUST00000023670.3
Clic6
chloride intracellular channel 6
chr18_-_61259987 0.901 ENSMUST00000170335.2
Rps2-ps10
ribosomal protein S2, pseudogene 10
chr14_-_59365410 0.900 ENSMUST00000161031.1
ENSMUST00000160425.1
Phf11d

PHD finger protein 11D

chr3_+_122044428 0.898 ENSMUST00000013995.8
Abca4
ATP-binding cassette, sub-family A (ABC1), member 4
chr6_-_24527546 0.896 ENSMUST00000118558.1
Ndufa5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr7_-_28050028 0.890 ENSMUST00000032824.9
Psmc4
proteasome (prosome, macropain) 26S subunit, ATPase, 4
chr9_+_58134535 0.890 ENSMUST00000128378.1
ENSMUST00000150820.1
ENSMUST00000167479.1
ENSMUST00000134450.1
Stra6



stimulated by retinoic acid gene 6



chr17_-_25880236 0.878 ENSMUST00000176696.1
ENSMUST00000095487.5
Wfikkn1

WAP, FS, Ig, KU, and NTR-containing protein 1

chr9_+_15520830 0.873 ENSMUST00000178999.1
Smco4
single-pass membrane protein with coiled-coil domains 4
chr3_-_88461182 0.867 ENSMUST00000166237.1
Sema4a
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr8_+_83389878 0.856 ENSMUST00000109831.2
Clgn
calmegin
chr9_+_58129062 0.843 ENSMUST00000085677.2
Stra6
stimulated by retinoic acid gene 6
chr15_+_52712434 0.843 ENSMUST00000037115.7
Med30
mediator complex subunit 30
chr14_+_65806066 0.842 ENSMUST00000139644.1
Pbk
PDZ binding kinase
chr4_-_43653560 0.831 ENSMUST00000107870.2
Spag8
sperm associated antigen 8
chr2_-_101883010 0.822 ENSMUST00000154525.1
Prr5l
proline rich 5 like
chr19_+_32389202 0.820 ENSMUST00000181612.1
2700046G09Rik
RIKEN cDNA 2700046G09 gene
chr9_+_75441518 0.819 ENSMUST00000048937.4
Leo1
Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr4_+_145510759 0.814 ENSMUST00000105742.1
ENSMUST00000136309.1
Gm13225

predicted gene 13225

chrX_-_17571563 0.814 ENSMUST00000177213.1
Fundc1
FUN14 domain containing 1
chr9_+_58129321 0.805 ENSMUST00000034880.3
Stra6
stimulated by retinoic acid gene 6
chrX_-_104671048 0.793 ENSMUST00000042070.5
Zdhhc15
zinc finger, DHHC domain containing 15
chr13_-_54565368 0.786 ENSMUST00000026989.8
4833439L19Rik
RIKEN cDNA 4833439L19 gene
chr4_-_94603239 0.784 ENSMUST00000107107.2
Plaa
phospholipase A2, activating protein
chr7_+_81858993 0.772 ENSMUST00000041890.1
Tm6sf1
transmembrane 6 superfamily member 1
chr3_+_103739366 0.769 ENSMUST00000106852.1
Gm10964
predicted gene 10964
chr2_-_60963192 0.764 ENSMUST00000028347.6
Rbms1
RNA binding motif, single stranded interacting protein 1
chr10_-_81349085 0.763 ENSMUST00000141171.1
Hmg20b
high mobility group 20B
chr11_-_98625661 0.756 ENSMUST00000104933.1
Gm12355
predicted gene 12355
chr3_-_107943705 0.750 ENSMUST00000106680.1
ENSMUST00000106684.1
ENSMUST00000106685.2
Gstm6


glutathione S-transferase, mu 6


chr1_-_170215380 0.749 ENSMUST00000027979.7
ENSMUST00000123399.1
Uhmk1

U2AF homology motif (UHM) kinase 1

chr9_+_58134017 0.746 ENSMUST00000134955.1
ENSMUST00000147134.1
ENSMUST00000170397.1
Stra6


stimulated by retinoic acid gene 6


chr18_+_76930017 0.741 ENSMUST00000026487.4
Ier3ip1
immediate early response 3 interacting protein 1
chr10_+_102158858 0.738 ENSMUST00000138522.1
ENSMUST00000163753.1
ENSMUST00000138016.1
Mgat4c


mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)


chr4_-_141606096 0.736 ENSMUST00000153189.1
Fblim1
filamin binding LIM protein 1
chr10_+_4611971 0.734 ENSMUST00000105590.1
ENSMUST00000067086.7
Esr1

estrogen receptor 1 (alpha)

chr3_-_150073620 0.731 ENSMUST00000057740.5
Rpsa-ps10
ribosomal protein SA, pseudogene 10
chr9_-_31131817 0.728 ENSMUST00000034478.2
St14
suppression of tumorigenicity 14 (colon carcinoma)
chr5_-_100373484 0.715 ENSMUST00000182433.1
Sec31a
Sec31 homolog A (S. cerevisiae)
chr7_+_143823135 0.715 ENSMUST00000128454.1
ENSMUST00000073878.5
Dhcr7

7-dehydrocholesterol reductase

chr15_-_20666750 0.710 ENSMUST00000052910.4
Acot10
acyl-CoA thioesterase 10
chr19_-_31765027 0.705 ENSMUST00000065067.6
Prkg1
protein kinase, cGMP-dependent, type I
chr16_+_44347121 0.694 ENSMUST00000050897.6
Spice1
spindle and centriole associated protein 1
chr9_-_22117123 0.678 ENSMUST00000013966.6
Elof1
elongation factor 1 homolog (ELF1, S. cerevisiae)
chr15_-_35938186 0.676 ENSMUST00000014457.8
Cox6c
cytochrome c oxidase subunit VIc
chr17_-_71002488 0.673 ENSMUST00000148960.1
Myl12a
myosin, light chain 12A, regulatory, non-sarcomeric
chr10_+_14523062 0.673 ENSMUST00000096020.5
Gm10335
predicted gene 10335
chr3_-_65392579 0.672 ENSMUST00000029414.5
Ssr3
signal sequence receptor, gamma
chr2_-_174346712 0.671 ENSMUST00000168292.1
Gm20721
predicted gene, 20721
chr2_-_25224653 0.670 ENSMUST00000043584.4
Tubb4b
tubulin, beta 4B class IVB
chr6_+_11925869 0.670 ENSMUST00000115510.1
ENSMUST00000115511.2
ENSMUST00000090632.4
Phf14


PHD finger protein 14


chr7_-_128596278 0.668 ENSMUST00000179317.1
Gm7258
predicted gene 7258
chr6_+_86628174 0.667 ENSMUST00000043400.6
Asprv1
aspartic peptidase, retroviral-like 1
chr12_-_87444017 0.665 ENSMUST00000091090.4
2700073G19Rik
RIKEN cDNA 2700073G19 gene
chr5_+_145140362 0.661 ENSMUST00000162594.1
ENSMUST00000162308.1
ENSMUST00000159018.1
ENSMUST00000160075.1
Bud31



BUD31 homolog (yeast)



chrX_-_134161928 0.655 ENSMUST00000033611.4
Xkrx
X Kell blood group precursor related X linked
chr11_+_21239279 0.654 ENSMUST00000006221.7
ENSMUST00000109578.1
Vps54

vacuolar protein sorting 54 (yeast)

chr13_-_63398167 0.652 ENSMUST00000160735.1
Fancc
Fanconi anemia, complementation group C
chr7_-_116084635 0.647 ENSMUST00000111755.3
Gm4353
predicted gene 4353
chr14_-_7483762 0.646 ENSMUST00000164366.1
Gm3752
predicted gene 3752
chr13_+_108670576 0.642 ENSMUST00000074680.6
Rps3a3
ribosomal protein S3A3
chr9_+_75037809 0.640 ENSMUST00000167885.1
Arpp19
cAMP-regulated phosphoprotein 19

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 21.7 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
1.8 12.6 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
1.3 3.9 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
1.0 3.1 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
1.0 2.9 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.9 4.3 GO:0046864 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865) alveolar primary septum development(GO:0061143)
0.7 2.2 GO:1902713 regulation of interferon-gamma secretion(GO:1902713)
0.7 2.1 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.6 0.6 GO:2000277 positive regulation of oxidative phosphorylation uncoupler activity(GO:2000277)
0.6 2.4 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.6 2.9 GO:0032901 positive regulation of neurotrophin production(GO:0032901)
0.6 2.3 GO:0061743 motor learning(GO:0061743)
0.6 2.3 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.5 1.6 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.5 2.5 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.5 1.4 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.4 1.3 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.4 1.6 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.4 2.8 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.4 2.4 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.4 1.2 GO:0051030 snRNA transport(GO:0051030)
0.4 1.9 GO:0072235 distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235)
0.4 0.7 GO:0060737 prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737)
0.4 1.4 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013) negative regulation of T-helper 17 type immune response(GO:2000317) regulation of T-helper 17 cell differentiation(GO:2000319) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.4 3.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.3 1.4 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.3 1.0 GO:1904959 regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959)
0.3 1.0 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.3 0.9 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.3 2.4 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.3 2.6 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.3 1.7 GO:0030916 otic vesicle formation(GO:0030916)
0.3 1.1 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.3 1.9 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.3 1.3 GO:0072103 renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.3 2.6 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.3 2.0 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.3 1.0 GO:1902340 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.2 0.7 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.2 1.9 GO:0009249 protein lipoylation(GO:0009249)
0.2 0.7 GO:0016132 brassinosteroid metabolic process(GO:0016131) brassinosteroid biosynthetic process(GO:0016132)
0.2 0.7 GO:2000224 regulation of testosterone biosynthetic process(GO:2000224)
0.2 2.3 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.2 6.7 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.2 0.7 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.2 0.6 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.2 1.1 GO:0060539 diaphragm development(GO:0060539)
0.2 0.5 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.2 0.5 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.2 1.1 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.2 1.4 GO:1990845 adaptive thermogenesis(GO:1990845)
0.2 0.5 GO:0018065 protein-cofactor linkage(GO:0018065)
0.2 0.5 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.1 1.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 1.0 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.1 0.4 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.1 1.8 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.1 0.4 GO:0016095 polyprenol catabolic process(GO:0016095)
0.1 1.2 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.1 1.0 GO:0006561 proline biosynthetic process(GO:0006561)
0.1 1.8 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 1.6 GO:0019321 pentose metabolic process(GO:0019321)
0.1 1.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.5 GO:0006244 pyrimidine nucleotide catabolic process(GO:0006244) pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.1 1.9 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 0.4 GO:0019401 alditol biosynthetic process(GO:0019401)
0.1 1.2 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.1 0.5 GO:0099527 postsynapse to nucleus signaling pathway(GO:0099527)
0.1 1.4 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.1 2.4 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.1 0.4 GO:0010796 regulation of multivesicular body size(GO:0010796)
0.1 2.2 GO:0006825 copper ion transport(GO:0006825)
0.1 0.5 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 2.3 GO:0043486 histone exchange(GO:0043486)
0.1 0.4 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 1.1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 2.4 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 0.8 GO:0038203 TORC2 signaling(GO:0038203)
0.1 3.4 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 0.5 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.6 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.1 0.4 GO:0035937 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.1 1.9 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.6 GO:0090234 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.1 0.9 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.1 0.3 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 0.9 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 0.4 GO:2001184 regulation of interleukin-12 secretion(GO:2001182) positive regulation of interleukin-12 secretion(GO:2001184)
0.1 1.0 GO:0009125 nucleoside monophosphate catabolic process(GO:0009125)
0.1 4.6 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.1 0.3 GO:0046898 response to cycloheximide(GO:0046898)
0.1 0.3 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 6.0 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.1 0.4 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.1 0.8 GO:0001711 endodermal cell fate commitment(GO:0001711)
0.1 1.1 GO:0000338 protein deneddylation(GO:0000338)
0.1 0.3 GO:0060414 response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865) aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.9 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 1.2 GO:0045830 positive regulation of isotype switching(GO:0045830)
0.1 0.9 GO:0045332 phospholipid translocation(GO:0045332)
0.1 0.8 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 1.2 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.1 0.7 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 1.1 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.5 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.3 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.1 0.8 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 0.8 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.2 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.2 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.0 1.0 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.2 GO:0021886 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.0 1.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.4 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.3 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.0 1.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.7 GO:0019430 removal of superoxide radicals(GO:0019430)
0.0 0.2 GO:0070813 hydrogen sulfide metabolic process(GO:0070813)
0.0 0.5 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.2 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.0 0.7 GO:2000269 regulation of fibroblast apoptotic process(GO:2000269)
0.0 0.8 GO:0031643 positive regulation of myelination(GO:0031643)
0.0 2.0 GO:0007338 single fertilization(GO:0007338)
0.0 0.7 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 3.8 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 2.4 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.3 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.3 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 1.0 GO:0009566 fertilization(GO:0009566)
0.0 1.3 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.2 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0 0.2 GO:0039702 cell separation after cytokinesis(GO:0000920) viral budding via host ESCRT complex(GO:0039702)
0.0 0.9 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.3 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.3 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.1 GO:0000076 DNA replication checkpoint(GO:0000076)
0.0 0.9 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.5 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.3 GO:0051984 positive regulation of chromosome segregation(GO:0051984)
0.0 0.5 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.3 GO:0006465 signal peptide processing(GO:0006465)
0.0 2.2 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.3 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.2 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.9 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.7 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
0.0 0.8 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.5 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.4 GO:0045116 protein neddylation(GO:0045116)
0.0 0.4 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 1.2 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.5 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.0 0.2 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.3 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.0 0.8 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435)
0.0 0.2 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.3 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.1 GO:0010826 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0 0.1 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.1 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.1 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.7 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.4 GO:0002011 morphogenesis of an epithelial sheet(GO:0002011)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 6.1 GO:0031262 Ndc80 complex(GO:0031262)
0.8 2.4 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.5 3.2 GO:0044305 calyx of Held(GO:0044305)
0.5 2.6 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.4 3.9 GO:0000805 X chromosome(GO:0000805)
0.3 1.9 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.3 2.7 GO:0097427 microtubule bundle(GO:0097427)
0.2 1.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.2 1.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 4.6 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.2 0.8 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.2 1.4 GO:0001520 outer dense fiber(GO:0001520)
0.1 0.3 GO:0070469 respiratory chain(GO:0070469)
0.1 0.6 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 0.4 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 1.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.9 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 4.5 GO:0097546 ciliary base(GO:0097546)
0.1 0.7 GO:0000938 GARP complex(GO:0000938)
0.1 1.4 GO:0070852 cell body fiber(GO:0070852)
0.1 0.7 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 0.9 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.1 1.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.9 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.5 GO:0005859 muscle myosin complex(GO:0005859)
0.1 0.7 GO:0089701 U2AF(GO:0089701)
0.1 2.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.8 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 1.1 GO:0031011 Ino80 complex(GO:0031011)
0.1 0.4 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 2.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 2.1 GO:0043194 axon initial segment(GO:0043194)
0.1 0.3 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.9 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.7 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 1.7 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.8 GO:0031932 TORC2 complex(GO:0031932)
0.1 0.7 GO:0016460 myosin II complex(GO:0016460)
0.1 1.0 GO:0060077 inhibitory synapse(GO:0060077)
0.0 2.0 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 4.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 1.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.3 GO:0005638 lamin filament(GO:0005638)
0.0 1.2 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 3.1 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.5 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 3.2 GO:0005643 nuclear pore(GO:0005643)
0.0 1.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.3 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.7 GO:0000800 lateral element(GO:0000800)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.3 GO:0031415 NatA complex(GO:0031415)
0.0 0.5 GO:0097470 ribbon synapse(GO:0097470)
0.0 2.7 GO:0005776 autophagosome(GO:0005776)
0.0 0.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 1.3 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.4 GO:0042788 polysomal ribosome(GO:0042788)
0.0 1.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.0 1.4 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.9 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.8 GO:0016592 mediator complex(GO:0016592)
0.0 0.6 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.8 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 3.0 GO:0043679 axon terminus(GO:0043679)
0.0 1.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.7 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.4 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.2 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 2.2 GO:0044297 cell body(GO:0044297)
0.0 4.8 GO:0005635 nuclear envelope(GO:0005635)
0.0 1.4 GO:0000776 kinetochore(GO:0000776)
0.0 0.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.4 GO:0031672 A band(GO:0031672)
0.0 1.4 GO:0043296 apical junction complex(GO:0043296)
0.0 1.0 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 0.4 GO:0000786 nucleosome(GO:0000786)
0.0 0.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.3 GO:0032040 small-subunit processome(GO:0032040)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 24.9 GO:0019992 diacylglycerol binding(GO:0019992)
1.3 3.9 GO:0005436 sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319)
0.6 1.9 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.5 2.4 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.4 1.3 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.4 2.5 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.4 2.0 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.4 1.8 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.4 2.9 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.4 2.2 GO:0016936 galactoside binding(GO:0016936)
0.3 1.4 GO:0016842 amidine-lyase activity(GO:0016842)
0.3 1.4 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.3 0.9 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.3 1.4 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.2 0.7 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.2 1.9 GO:0048495 Roundabout binding(GO:0048495)
0.2 1.0 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.2 0.7 GO:0009918 sterol delta7 reductase activity(GO:0009918) 7-dehydrocholesterol reductase activity(GO:0047598)
0.2 3.3 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.2 1.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.2 0.8 GO:1990269 RNA polymerase II C-terminal domain phosphoserine binding(GO:1990269)
0.2 5.8 GO:0043014 alpha-tubulin binding(GO:0043014)
0.2 0.5 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.2 0.5 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.2 0.7 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.2 1.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.2 3.1 GO:0001848 complement binding(GO:0001848)
0.2 1.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 1.0 GO:1903136 cuprous ion binding(GO:1903136)
0.1 1.3 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.4 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.1 0.4 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.1 4.3 GO:0051183 vitamin transporter activity(GO:0051183)
0.1 0.5 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 3.0 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.9 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.1 0.9 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 1.8 GO:0031005 filamin binding(GO:0031005)
0.1 1.4 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 0.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 4.6 GO:0042169 SH2 domain binding(GO:0042169)
0.1 1.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 2.0 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.1 0.4 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.1 0.3 GO:0048019 receptor antagonist activity(GO:0048019)
0.1 1.2 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.4 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.3 GO:0016880 acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 1.4 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 2.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.8 GO:0016004 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.1 2.4 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 0.5 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 2.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.2 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.1 0.8 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1 0.3 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 3.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.3 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.5 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 0.5 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.5 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 0.6 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 1.4 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.1 0.5 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 1.0 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 2.4 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 0.3 GO:0000403 Y-form DNA binding(GO:0000403)
0.1 0.3 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.1 0.7 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 1.1 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 1.0 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.3 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.0 1.0 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.6 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.2 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 3.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.8 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 1.6 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.5 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.9 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.4 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.6 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 4.0 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.0 0.8 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.8 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 2.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.8 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.7 GO:0050699 WW domain binding(GO:0050699)
0.0 2.7 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.2 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.4 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.4 GO:0017091 AU-rich element binding(GO:0017091)
0.0 1.6 GO:0051015 actin filament binding(GO:0051015)
0.0 1.8 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.1 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 1.0 GO:0043178 alcohol binding(GO:0043178)
0.0 0.1 GO:0070628 proteasome binding(GO:0070628)
0.0 0.0 GO:0051747 cytosine C-5 DNA demethylase activity(GO:0051747)
0.0 0.8 GO:0008565 protein transporter activity(GO:0008565)
0.0 1.8 GO:0003735 structural constituent of ribosome(GO:0003735)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 20.9 PID_RAS_PATHWAY Regulation of Ras family activation
0.2 6.1 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.4 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 0.5 PID_PI3KCI_AKT_PATHWAY Class I PI3K signaling events mediated by Akt
0.1 1.8 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 2.1 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.1 1.4 PID_IL27_PATHWAY IL27-mediated signaling events
0.0 3.1 PID_PLK1_PATHWAY PLK1 signaling events
0.0 1.8 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.5 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 1.1 PID_MYC_PATHWAY C-MYC pathway
0.0 0.5 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.3 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.4 PID_BMP_PATHWAY BMP receptor signaling
0.0 0.5 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 2.3 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.2 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.6 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.5 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.0 1.3 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.7 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 0.4 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.7 PID_BARD1_PATHWAY BARD1 signaling events
0.0 0.3 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.5 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.4 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 0.4 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 0.3 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 22.4 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.3 3.1 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.2 3.0 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.2 4.4 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.2 1.8 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 2.6 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.6 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 0.4 REACTOME_ANDROGEN_BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 8.6 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 2.0 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 3.6 REACTOME_GLUCAGON_SIGNALING_IN_METABOLIC_REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.1 2.3 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.6 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.5 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 2.0 REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.1 1.3 REACTOME_KINESINS Genes involved in Kinesins
0.1 3.0 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 2.7 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 1.4 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 1.2 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.0 4.0 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_ Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.4 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.0 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.9 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.5 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.9 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.4 REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.7 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.0 2.9 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.0 0.9 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.4 REACTOME_P38MAPK_EVENTS Genes involved in p38MAPK events
0.0 0.6 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.3 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.0 1.0 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.5 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.0 0.7 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.9 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.9 REACTOME_AUTODEGRADATION_OF_THE_E3_UBIQUITIN_LIGASE_COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 1.1 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.3 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.3 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.8 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.2 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi