Motif ID: Pou4f1_Pou6f1

Z-value: 0.738

Transcription factors associated with Pou4f1_Pou6f1:

Gene SymbolEntrez IDGene Name
Pou4f1 ENSMUSG00000048349.8 Pou4f1
Pou6f1 ENSMUSG00000009739.10 Pou6f1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou6f1mm10_v2_chr15_-_100599983_1006000390.645.8e-06Click!
Pou4f1mm10_v2_chr14_-_104467984_104468041-0.279.0e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Pou4f1_Pou6f1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_30353468 4.016 ENSMUST00000112249.1
Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr13_+_42681513 3.315 ENSMUST00000149235.1
Phactr1
phosphatase and actin regulator 1
chr15_-_100599864 3.089 ENSMUST00000177247.2
ENSMUST00000177505.2
Pou6f1

POU domain, class 6, transcription factor 1

chr15_+_18818895 3.034 ENSMUST00000166873.2
Cdh10
cadherin 10
chr8_+_12984246 2.641 ENSMUST00000110873.3
ENSMUST00000173006.1
ENSMUST00000145067.1
Mcf2l


mcf.2 transforming sequence-like


chr6_+_80018877 2.561 ENSMUST00000147663.1
ENSMUST00000128718.1
ENSMUST00000126005.1
ENSMUST00000133918.1
Lrrtm4



leucine rich repeat transmembrane neuronal 4



chr15_-_100599983 2.504 ENSMUST00000073837.6
Pou6f1
POU domain, class 6, transcription factor 1
chr9_+_113812547 2.427 ENSMUST00000166734.2
ENSMUST00000111838.2
ENSMUST00000163895.2
Clasp2


CLIP associating protein 2


chr9_-_103222063 2.353 ENSMUST00000170904.1
Trf
transferrin
chr9_-_40346290 2.353 ENSMUST00000121357.1
Gramd1b
GRAM domain containing 1B
chr6_+_80019008 2.324 ENSMUST00000126399.1
ENSMUST00000136421.1
Lrrtm4

leucine rich repeat transmembrane neuronal 4

chr1_-_56978534 2.137 ENSMUST00000177282.1
Satb2
special AT-rich sequence binding protein 2
chr15_+_100870670 2.071 ENSMUST00000082209.6
Scn8a
sodium channel, voltage-gated, type VIII, alpha
chr17_-_50094277 2.063 ENSMUST00000113195.1
Rftn1
raftlin lipid raft linker 1
chr2_-_77519565 2.051 ENSMUST00000111830.2
Zfp385b
zinc finger protein 385B
chr2_+_176711933 1.979 ENSMUST00000108983.2
Gm14305
predicted gene 14305
chr4_+_152338619 1.909 ENSMUST00000030775.5
ENSMUST00000164662.1
Chd5

chromodomain helicase DNA binding protein 5

chr2_-_177202829 1.886 ENSMUST00000133301.1
Gm14410
predicted gene 14410
chr18_+_37504264 1.719 ENSMUST00000052179.6
Pcdhb20
protocadherin beta 20
chr1_+_180101144 1.690 ENSMUST00000133890.1
Cdc42bpa
CDC42 binding protein kinase alpha
chr2_+_175968942 1.636 ENSMUST00000109008.3
Gm2026
predicted gene 2026
chr2_+_176802233 1.586 ENSMUST00000132883.1
Gm14295
predicted gene 14295
chr2_+_68104671 1.569 ENSMUST00000042456.3
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr2_-_175203061 1.549 ENSMUST00000165892.1
Gm14391
predicted gene 14391
chr13_+_104287855 1.537 ENSMUST00000065766.6
Adamts6
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 6
chr2_-_175432182 1.531 ENSMUST00000109046.3
Gm4724
predicted gene 4724
chr2_-_176483160 1.499 ENSMUST00000122097.2
Gm14434
predicted gene 14434
chr1_-_176807124 1.494 ENSMUST00000057037.7
Cep170
centrosomal protein 170
chr8_+_69300776 1.490 ENSMUST00000078257.6
D130040H23Rik
RIKEN cDNA D130040H23 gene
chr4_+_154964117 1.476 ENSMUST00000030931.4
ENSMUST00000070953.4
Pank4

pantothenate kinase 4

chr5_-_70842617 1.451 ENSMUST00000031119.1
Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr15_+_81811414 1.430 ENSMUST00000023024.7
Tef
thyrotroph embryonic factor
chr2_+_83812567 1.428 ENSMUST00000051454.3
Fam171b
family with sequence similarity 171, member B
chr18_+_69593361 1.424 ENSMUST00000114978.2
ENSMUST00000114977.1
Tcf4

transcription factor 4

chr13_+_18717289 1.362 ENSMUST00000072961.4
Vps41
vacuolar protein sorting 41 (yeast)
chr14_-_100149764 1.361 ENSMUST00000097079.4
Klf12
Kruppel-like factor 12
chr19_+_8591254 1.316 ENSMUST00000010251.3
ENSMUST00000170817.1
Slc22a8

solute carrier family 22 (organic anion transporter), member 8

chr2_+_177004553 1.295 ENSMUST00000126358.1
Gm14419
predicted gene 14419
chr1_-_166002613 1.270 ENSMUST00000177358.1
ENSMUST00000160908.1
ENSMUST00000027850.8
ENSMUST00000160260.2
Pou2f1



POU domain, class 2, transcription factor 1



chr6_+_21215472 1.257 ENSMUST00000081542.5
Kcnd2
potassium voltage-gated channel, Shal-related family, member 2
chr2_+_82053222 1.256 ENSMUST00000047527.7
Zfp804a
zinc finger protein 804A
chr5_-_138619751 1.245 ENSMUST00000085852.4
ENSMUST00000110905.2
Zfp68

zinc finger protein 68

chr2_+_84734050 1.234 ENSMUST00000090729.2
Ypel4
yippee-like 4 (Drosophila)
chr18_+_59062462 1.212 ENSMUST00000058633.2
ENSMUST00000175897.1
ENSMUST00000118510.1
ENSMUST00000175830.1
A730017C20Rik



RIKEN cDNA A730017C20 gene



chr1_-_165934900 1.211 ENSMUST00000069609.5
ENSMUST00000111427.2
ENSMUST00000111426.4
Pou2f1


POU domain, class 2, transcription factor 1


chr15_+_92161343 1.205 ENSMUST00000068378.5
Cntn1
contactin 1
chr1_-_22315792 1.197 ENSMUST00000164877.1
Rims1
regulating synaptic membrane exocytosis 1
chr5_-_39644634 1.195 ENSMUST00000053116.6
Hs3st1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chrX_+_112615301 1.193 ENSMUST00000122805.1
Zfp711
zinc finger protein 711
chr10_+_7589788 1.192 ENSMUST00000134346.1
ENSMUST00000019931.5
Lrp11

low density lipoprotein receptor-related protein 11

chr13_-_62371936 1.188 ENSMUST00000107989.3
Gm3604
predicted gene 3604
chr5_-_138619702 1.174 ENSMUST00000063262.4
Zfp68
zinc finger protein 68
chr1_+_179961110 1.162 ENSMUST00000076687.5
ENSMUST00000097450.3
Cdc42bpa

CDC42 binding protein kinase alpha

chr11_-_100939457 1.136 ENSMUST00000138438.1
Stat3
signal transducer and activator of transcription 3
chr7_-_99182681 1.097 ENSMUST00000033001.4
Dgat2
diacylglycerol O-acyltransferase 2
chr2_-_176149825 1.092 ENSMUST00000109049.3
ENSMUST00000179349.1
Gm2004

predicted gene 2004

chr6_+_58831456 1.082 ENSMUST00000141600.1
ENSMUST00000122981.1
Herc3

hect domain and RLD 3

chr11_-_100939357 1.079 ENSMUST00000092671.5
ENSMUST00000103114.1
Stat3

signal transducer and activator of transcription 3

chr11_+_98348404 1.075 ENSMUST00000078694.6
Ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr2_+_102658640 1.071 ENSMUST00000080210.3
Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr18_+_59062282 1.066 ENSMUST00000165666.2
A730017C20Rik
RIKEN cDNA A730017C20 gene
chr10_+_7589885 1.032 ENSMUST00000130590.1
ENSMUST00000135907.1
Lrp11

low density lipoprotein receptor-related protein 11

chr1_-_60043087 1.030 ENSMUST00000027172.6
Ica1l
islet cell autoantigen 1-like
chr7_-_45370559 1.014 ENSMUST00000003971.7
Lin7b
lin-7 homolog B (C. elegans)
chr2_+_97467657 1.012 ENSMUST00000059049.7
Lrrc4c
leucine rich repeat containing 4C
chr2_+_177762898 1.010 ENSMUST00000119838.2
Gm14322
predicted gene 14322
chr15_-_58214882 1.008 ENSMUST00000022986.6
Fbxo32
F-box protein 32
chr3_-_18243289 1.004 ENSMUST00000035625.6
Cyp7b1
cytochrome P450, family 7, subfamily b, polypeptide 1
chr1_-_180996145 0.996 ENSMUST00000154133.1
Ephx1
epoxide hydrolase 1, microsomal
chr2_-_168734236 0.991 ENSMUST00000109175.2
Atp9a
ATPase, class II, type 9A
chrX_+_150547375 0.984 ENSMUST00000066337.6
ENSMUST00000112715.1
Alas2

aminolevulinic acid synthase 2, erythroid

chr1_+_180109192 0.982 ENSMUST00000143176.1
ENSMUST00000135056.1
Cdc42bpa

CDC42 binding protein kinase alpha

chr2_+_175643978 0.966 ENSMUST00000177700.1
ENSMUST00000178120.1
Gm11007

predicted gene 11007

chr17_-_36032682 0.961 ENSMUST00000102678.4
H2-T23
histocompatibility 2, T region locus 23
chr3_+_28263205 0.954 ENSMUST00000159236.2
Tnik
TRAF2 and NCK interacting kinase
chr11_-_42182924 0.933 ENSMUST00000020707.5
ENSMUST00000132971.1
Gabra1

gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1

chr3_-_152982240 0.933 ENSMUST00000044278.5
St6galnac5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr11_-_100939540 0.930 ENSMUST00000127638.1
Stat3
signal transducer and activator of transcription 3
chr5_+_13398688 0.922 ENSMUST00000125629.1
Sema3a
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr2_+_175741537 0.920 ENSMUST00000177981.1
ENSMUST00000178133.1
Gm2007

predicted gene 2007

chr11_+_94044111 0.911 ENSMUST00000132079.1
Spag9
sperm associated antigen 9
chr3_+_26331150 0.911 ENSMUST00000099182.2
A830092H15Rik
RIKEN cDNA A830092H15 gene
chr3_-_113574758 0.905 ENSMUST00000106540.1
Amy1
amylase 1, salivary
chr13_+_109926832 0.891 ENSMUST00000117420.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr5_-_106925839 0.874 ENSMUST00000112690.3
Hfm1
HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
chr4_+_102254993 0.873 ENSMUST00000106908.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr1_-_134955908 0.872 ENSMUST00000045665.6
ENSMUST00000086444.4
ENSMUST00000112163.1
Ppp1r12b


protein phosphatase 1, regulatory (inhibitor) subunit 12B


chr8_-_41016295 0.866 ENSMUST00000131965.1
Mtus1
mitochondrial tumor suppressor 1
chr14_-_118923070 0.864 ENSMUST00000047208.5
Dzip1
DAZ interacting protein 1
chr5_+_13399309 0.864 ENSMUST00000030714.7
ENSMUST00000141968.1
Sema3a

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A

chr2_-_120245157 0.841 ENSMUST00000090071.4
Pla2g4e
phospholipase A2, group IVE
chr19_-_40402267 0.826 ENSMUST00000099467.3
ENSMUST00000099466.3
ENSMUST00000165212.1
ENSMUST00000165469.1
Sorbs1



sorbin and SH3 domain containing 1



chr2_+_153031852 0.805 ENSMUST00000037235.6
Xkr7
X Kell blood group precursor related family member 7 homolog
chr9_-_58202281 0.785 ENSMUST00000163897.1
Islr2
immunoglobulin superfamily containing leucine-rich repeat 2
chr9_-_13245741 0.783 ENSMUST00000110582.2
Jrkl
jerky homolog-like (mouse)
chr17_-_6621267 0.772 ENSMUST00000115772.3
Tmem181c-ps
transmembrane protein 181C, pseudogene
chr2_-_148732457 0.765 ENSMUST00000028926.6
Napb
N-ethylmaleimide sensitive fusion protein attachment protein beta
chr6_-_86765866 0.757 ENSMUST00000113675.1
Anxa4
annexin A4
chr14_-_18893376 0.750 ENSMUST00000151926.1
Ube2e2
ubiquitin-conjugating enzyme E2E 2
chr13_-_62777089 0.743 ENSMUST00000167516.2
Gm5141
predicted gene 5141
chr11_+_94044194 0.738 ENSMUST00000092777.4
ENSMUST00000075695.6
Spag9

sperm associated antigen 9

chr15_+_79690869 0.717 ENSMUST00000046463.8
Gtpbp1
GTP binding protein 1
chr1_-_166002591 0.711 ENSMUST00000111429.4
ENSMUST00000176800.1
Pou2f1

POU domain, class 2, transcription factor 1

chr3_-_86999284 0.707 ENSMUST00000063869.5
ENSMUST00000029717.2
Cd1d1

CD1d1 antigen

chr11_+_93098404 0.701 ENSMUST00000107859.1
ENSMUST00000042943.6
ENSMUST00000107861.1
ENSMUST00000107858.2
Car10



carbonic anhydrase 10



chr6_+_86404257 0.691 ENSMUST00000095752.2
ENSMUST00000130967.1
Tia1

cytotoxic granule-associated RNA binding protein 1

chr10_-_62899118 0.683 ENSMUST00000174189.1
Tet1
tet methylcytosine dioxygenase 1
chr10_-_56228636 0.667 ENSMUST00000099739.3
Tbc1d32
TBC1 domain family, member 32
chr4_+_43384332 0.652 ENSMUST00000136360.1
Rusc2
RUN and SH3 domain containing 2
chr6_-_86765807 0.646 ENSMUST00000123732.1
Anxa4
annexin A4
chr8_+_83666827 0.638 ENSMUST00000019608.5
Ptger1
prostaglandin E receptor 1 (subtype EP1)
chr9_-_124311750 0.625 ENSMUST00000177714.1
2010315B03Rik
RIKEN cDNA 2010315B03 gene
chr4_+_102589687 0.624 ENSMUST00000097949.4
ENSMUST00000106901.1
Pde4b

phosphodiesterase 4B, cAMP specific

chr16_+_91269759 0.619 ENSMUST00000056882.5
Olig1
oligodendrocyte transcription factor 1
chr3_+_53845086 0.618 ENSMUST00000108014.1
Gm10985
predicted gene 10985
chr13_-_62520451 0.601 ENSMUST00000082203.6
ENSMUST00000101547.4
Zfp934

zinc finger protein 934

chr9_-_101034857 0.592 ENSMUST00000142676.1
ENSMUST00000149322.1
Pccb

propionyl Coenzyme A carboxylase, beta polypeptide

chr6_-_36811361 0.585 ENSMUST00000101534.1
Ptn
pleiotrophin
chr2_+_176230177 0.584 ENSMUST00000135430.1
2210418O10Rik
RIKEN cDNA 2210418O10 gene
chr4_-_119538769 0.582 ENSMUST00000079611.6
AA415398
expressed sequence AA415398
chr8_+_110618577 0.582 ENSMUST00000034190.9
Vac14
Vac14 homolog (S. cerevisiae)
chrX_+_106027259 0.555 ENSMUST00000113557.1
Atp7a
ATPase, Cu++ transporting, alpha polypeptide
chr13_+_108860072 0.553 ENSMUST00000177907.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr16_-_22439570 0.549 ENSMUST00000170393.1
Etv5
ets variant gene 5
chrX_+_106027300 0.548 ENSMUST00000055941.6
Atp7a
ATPase, Cu++ transporting, alpha polypeptide
chr9_-_101034892 0.537 ENSMUST00000035116.5
Pccb
propionyl Coenzyme A carboxylase, beta polypeptide
chr10_+_29143996 0.536 ENSMUST00000092629.2
Soga3
SOGA family member 3
chr11_+_94044331 0.534 ENSMUST00000024979.8
Spag9
sperm associated antigen 9
chr8_-_67974567 0.533 ENSMUST00000098696.3
ENSMUST00000038959.9
ENSMUST00000093469.4
Psd3


pleckstrin and Sec7 domain containing 3


chr19_-_20390944 0.528 ENSMUST00000025561.7
Anxa1
annexin A1
chr4_-_138326234 0.520 ENSMUST00000105817.3
ENSMUST00000030536.6
Pink1

PTEN induced putative kinase 1

chr18_-_37020679 0.507 ENSMUST00000097612.2
Gm10545
predicted gene 10545
chr10_-_29144194 0.496 ENSMUST00000070359.2
Gm9996
predicted gene 9996
chr13_-_62607499 0.490 ENSMUST00000091563.4
6720489N17Rik
RIKEN cDNA 6720489N17 gene
chr11_+_94044241 0.487 ENSMUST00000103168.3
Spag9
sperm associated antigen 9
chr14_-_78088994 0.487 ENSMUST00000118785.2
ENSMUST00000066437.4
Fam216b

family with sequence similarity 216, member B

chr3_+_66985680 0.485 ENSMUST00000065047.6
Rsrc1
arginine/serine-rich coiled-coil 1
chr12_-_27160311 0.472 ENSMUST00000182473.1
ENSMUST00000177636.1
ENSMUST00000183238.1
Gm9866


predicted gene 9866


chr10_+_100488289 0.465 ENSMUST00000164751.1
Cep290
centrosomal protein 290
chr4_-_119190005 0.457 ENSMUST00000138395.1
ENSMUST00000156746.1
Ermap

erythroblast membrane-associated protein

chr18_-_35498856 0.456 ENSMUST00000025215.8
Sil1
endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae)
chr11_+_116848901 0.456 ENSMUST00000143184.1
Mettl23
methyltransferase like 23
chr9_-_78109020 0.454 ENSMUST00000001402.7
Fbxo9
f-box protein 9
chr7_-_30195046 0.453 ENSMUST00000001845.5
Capns1
calpain, small subunit 1
chr14_+_21750525 0.449 ENSMUST00000022292.3
Samd8
sterile alpha motif domain containing 8
chr13_+_83504032 0.446 ENSMUST00000163888.1
ENSMUST00000005722.7
Mef2c

myocyte enhancer factor 2C

chr19_+_29367447 0.445 ENSMUST00000016640.7
Cd274
CD274 antigen
chr1_-_132390301 0.436 ENSMUST00000132435.1
Tmcc2
transmembrane and coiled-coil domains 2
chr16_+_87354185 0.433 ENSMUST00000054442.4
ENSMUST00000118310.1
ENSMUST00000120284.1
ENSMUST00000118115.1
N6amt1



N-6 adenine-specific DNA methyltransferase 1 (putative)



chr10_+_119992962 0.414 ENSMUST00000154238.1
Grip1
glutamate receptor interacting protein 1
chr15_-_75894474 0.414 ENSMUST00000023237.6
Naprt1
nicotinate phosphoribosyltransferase domain containing 1
chr17_+_85028347 0.412 ENSMUST00000024944.7
Slc3a1
solute carrier family 3, member 1
chr17_-_32822200 0.396 ENSMUST00000179695.1
Zfp799
zinc finger protein 799
chr11_-_50841546 0.391 ENSMUST00000109133.1
ENSMUST00000109134.1
ENSMUST00000049625.1
Zfp879


zinc finger protein 879


chr6_+_125009261 0.389 ENSMUST00000112427.1
Zfp384
zinc finger protein 384
chr13_-_96471160 0.388 ENSMUST00000055607.5
ENSMUST00000181613.2
Ankdd1b

ankyrin repeat and death domain containing 1B

chr4_-_41569502 0.383 ENSMUST00000108049.2
ENSMUST00000108052.3
ENSMUST00000108050.1
Fam219a


family with sequence similarity 219, member A


chrX_+_99042581 0.383 ENSMUST00000036606.7
Stard8
START domain containing 8
chr13_-_64129305 0.367 ENSMUST00000099441.4
Slc35d2
solute carrier family 35, member D2
chr17_-_51826562 0.363 ENSMUST00000024720.4
ENSMUST00000129667.1
ENSMUST00000156051.1
ENSMUST00000169480.1
ENSMUST00000148559.1
Satb1




special AT-rich sequence binding protein 1




chr3_-_105053125 0.358 ENSMUST00000077548.5
Cttnbp2nl
CTTNBP2 N-terminal like
chr12_+_55124528 0.354 ENSMUST00000177768.1
Fam177a
family with sequence similarity 177, member A
chr3_+_68572245 0.345 ENSMUST00000170788.2
Schip1
schwannomin interacting protein 1
chr7_+_64185459 0.343 ENSMUST00000177102.2
ENSMUST00000107519.1
ENSMUST00000137650.1
ENSMUST00000032737.5
ENSMUST00000107515.1
ENSMUST00000144996.1
Trpm1





transient receptor potential cation channel, subfamily M, member 1





chr6_+_127149389 0.342 ENSMUST00000180811.1
9330179D12Rik
RIKEN cDNA 9330179D12 gene
chr6_+_125009232 0.338 ENSMUST00000112428.1
Zfp384
zinc finger protein 384
chr6_+_125009113 0.337 ENSMUST00000054553.4
Zfp384
zinc finger protein 384
chr5_+_24394388 0.335 ENSMUST00000115074.1
Abcb8
ATP-binding cassette, sub-family B (MDR/TAP), member 8
chr4_-_45532470 0.331 ENSMUST00000147448.1
Shb
src homology 2 domain-containing transforming protein B
chr13_-_38960846 0.322 ENSMUST00000021870.4
Slc35b3
solute carrier family 35, member B3
chr12_-_59061425 0.314 ENSMUST00000021380.8
Trappc6b
trafficking protein particle complex 6B
chr6_-_102464667 0.309 ENSMUST00000032159.6
Cntn3
contactin 3
chr14_+_25607797 0.308 ENSMUST00000160229.1
Zmiz1
zinc finger, MIZ-type containing 1
chr10_+_127266256 0.304 ENSMUST00000026479.9
Dctn2
dynactin 2
chr4_+_146654927 0.301 ENSMUST00000070932.3
Gm13248
predicted gene 13248
chrX_-_88115632 0.296 ENSMUST00000113966.1
ENSMUST00000113964.1
Il1rapl1

interleukin 1 receptor accessory protein-like 1

chr1_+_24005505 0.296 ENSMUST00000181961.1
Gm26524
predicted gene, 26524
chr3_+_90341654 0.288 ENSMUST00000049382.4
Gatad2b
GATA zinc finger domain containing 2B
chr3_-_105052948 0.278 ENSMUST00000098763.2
Cttnbp2nl
CTTNBP2 N-terminal like
chr15_-_58847321 0.275 ENSMUST00000075109.5
Ube2d4
ubiquitin-conjugating enzyme E2D 4
chr13_-_95250166 0.275 ENSMUST00000162153.1
ENSMUST00000160957.2
ENSMUST00000159598.1
ENSMUST00000162412.1
Pde8b



phosphodiesterase 8B



chr4_+_101507947 0.273 ENSMUST00000149047.1
ENSMUST00000106929.3
Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr13_+_55600055 0.269 ENSMUST00000133176.1
ENSMUST00000064701.6
B4galt7

xylosylprotein beta1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I)

chr6_-_122609964 0.268 ENSMUST00000032211.4
Gdf3
growth differentiation factor 3
chrM_+_9870 0.266 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr17_+_66111605 0.265 ENSMUST00000116556.2
Wash
WAS protein family homolog
chr8_-_27128615 0.261 ENSMUST00000033877.4
Brf2
BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like
chr11_-_69795930 0.260 ENSMUST00000045971.8
Chrnb1
cholinergic receptor, nicotinic, beta polypeptide 1 (muscle)
chr18_+_55057557 0.250 ENSMUST00000181765.1
Gm4221
predicted gene 4221
chr9_+_54538984 0.249 ENSMUST00000060242.5
ENSMUST00000118413.1
Sh2d7

SH2 domain containing 7

chr6_-_39420418 0.249 ENSMUST00000031985.6
Mkrn1
makorin, ring finger protein, 1
chr10_-_125328957 0.246 ENSMUST00000063318.2
Slc16a7
solute carrier family 16 (monocarboxylic acid transporters), member 7
chr1_-_133661318 0.242 ENSMUST00000027736.6
ENSMUST00000179598.1
Zc3h11a
Zbed6
zinc finger CCCH type containing 11A
zinc finger, BED domain containing 6
chr11_-_6475992 0.242 ENSMUST00000179343.1
Purb
purine rich element binding protein B
chr17_+_66111529 0.241 ENSMUST00000072383.6
Wash
WAS protein family homolog
chr8_-_95853501 0.238 ENSMUST00000040481.3
Slc38a7
solute carrier family 38, member 7
chr14_-_59440779 0.233 ENSMUST00000111253.2
ENSMUST00000095775.3
ENSMUST00000161459.1
Setdb2


SET domain, bifurcated 2


chr9_-_58201705 0.230 ENSMUST00000163200.1
ENSMUST00000165276.1
Islr2

immunoglobulin superfamily containing leucine-rich repeat 2

chr4_-_149909719 0.226 ENSMUST00000105685.1
Spsb1
splA/ryanodine receptor domain and SOCS box containing 1
chr9_+_78109188 0.225 ENSMUST00000118869.1
ENSMUST00000125615.1
Ick

intestinal cell kinase


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.0 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.8 3.1 GO:1902724 positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.6 2.2 GO:0009414 response to water deprivation(GO:0009414)
0.5 1.0 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.4 1.3 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.4 2.1 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.4 2.4 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.4 1.1 GO:1904959 regulation of iron ion transport(GO:0034756) regulation of iron ion transmembrane transport(GO:0034759) elastin biosynthetic process(GO:0051542) copper ion export(GO:0060003) regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959)
0.4 1.1 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.4 1.8 GO:0021856 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.3 2.4 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.3 2.7 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.3 1.9 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.3 1.0 GO:2000564 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.3 1.2 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.3 0.6 GO:1904395 positive regulation of postsynaptic membrane organization(GO:1901628) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.3 1.9 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.3 1.4 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.3 4.9 GO:1901629 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688) regulation of presynaptic membrane organization(GO:1901629)
0.2 1.0 GO:0007256 activation of JNKK activity(GO:0007256)
0.2 0.7 GO:0042097 interleukin-4 biosynthetic process(GO:0042097) regulation of interleukin-4 biosynthetic process(GO:0045402) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.2 3.0 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 1.6 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.2 0.4 GO:2000111 positive regulation of macrophage apoptotic process(GO:2000111)
0.2 1.0 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.2 1.1 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.2 2.5 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.2 1.1 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 1.0 GO:0035754 B cell chemotaxis(GO:0035754)
0.1 4.0 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1 0.7 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.1 0.5 GO:0036482 neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384)
0.1 1.4 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.7 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.9 GO:0071420 cellular response to histamine(GO:0071420)
0.1 0.5 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 1.5 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.8 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.1 2.6 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 0.8 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 2.1 GO:0002076 osteoblast development(GO:0002076)
0.1 0.3 GO:0035106 operant conditioning(GO:0035106)
0.1 0.9 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.1 1.0 GO:0034312 diol biosynthetic process(GO:0034312)
0.1 0.4 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.1 0.2 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) regulation of connective tissue replacement(GO:1905203)
0.1 1.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.7 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.1 0.4 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.2 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.1 1.3 GO:0045475 locomotor rhythm(GO:0045475)
0.1 1.0 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.1 0.2 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780)
0.0 0.3 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.3 GO:0072318 clathrin coat disassembly(GO:0072318)
0.0 0.2 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 0.3 GO:0048859 formation of anatomical boundary(GO:0048859)
0.0 0.3 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.2 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0 2.1 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.1 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.0 0.3 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 3.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 4.1 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.9 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.3 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.3 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.4 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:1900110 negative regulation of histone H3-K9 dimethylation(GO:1900110)
0.0 0.8 GO:0009395 phospholipid catabolic process(GO:0009395)
0.0 1.0 GO:0015914 phospholipid transport(GO:0015914)
0.0 1.2 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.7 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 0.5 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0001553 luteinization(GO:0001553)
0.0 1.0 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.9 GO:0051220 cytoplasmic sequestering of protein(GO:0051220)
0.0 1.5 GO:0060976 coronary vasculature development(GO:0060976)
0.0 0.1 GO:0036337 Fas signaling pathway(GO:0036337)
0.0 0.2 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.0 0.3 GO:0032402 melanosome transport(GO:0032402)
0.0 0.6 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.5 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.1 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.2 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.2 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.6 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 0.2 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.9 GO:0009062 fatty acid catabolic process(GO:0009062)
0.0 0.1 GO:0006953 acute-phase response(GO:0006953)
0.0 0.1 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.4 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.4 4.0 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.3 2.4 GO:0097433 dense body(GO:0097433)
0.3 0.8 GO:0005899 insulin receptor complex(GO:0005899)
0.2 1.2 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.2 1.4 GO:0033263 CORVET complex(GO:0033263)
0.2 0.8 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 1.0 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 2.1 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 4.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.5 GO:0001533 cornified envelope(GO:0001533)
0.1 3.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 0.6 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 1.0 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 1.9 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 0.7 GO:0097165 nuclear stress granule(GO:0097165)
0.1 0.9 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 0.5 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.9 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 0.7 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 1.5 GO:0034707 chloride channel complex(GO:0034707)
0.1 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 1.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 1.1 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 5.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.5 GO:0036038 MKS complex(GO:0036038)
0.0 0.9 GO:0031672 A band(GO:0031672)
0.0 1.1 GO:0030673 axolemma(GO:0030673)
0.0 3.4 GO:0042641 actomyosin(GO:0042641)
0.0 2.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.1 GO:0000235 astral microtubule(GO:0000235)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 2.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:0097542 ciliary tip(GO:0097542)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 1.5 GO:0030017 sarcomere(GO:0030017)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.5 GO:0005814 centriole(GO:0005814)
0.0 1.1 GO:0005811 lipid particle(GO:0005811)
0.0 6.2 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 0.5 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 1.8 GO:0055037 recycling endosome(GO:0055037)
0.0 1.0 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 1.9 GO:0001650 fibrillar center(GO:0001650)
0.0 0.6 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.2 GO:0000346 transcription export complex(GO:0000346)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.0 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.5 1.9 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.4 1.6 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.4 1.1 GO:0004658 propionyl-CoA carboxylase activity(GO:0004658)
0.4 1.1 GO:0043682 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.4 1.1 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.4 1.1 GO:0031752 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.4 1.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3 3.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.3 2.4 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.3 1.0 GO:0016748 succinyltransferase activity(GO:0016748)
0.3 0.9 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.3 1.5 GO:0004594 pantothenate kinase activity(GO:0004594)
0.3 0.6 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.3 1.3 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.2 1.0 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.2 1.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.2 4.9 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.2 0.8 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.2 1.3 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.2 2.4 GO:0002162 dystroglycan binding(GO:0002162)
0.2 1.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.2 2.7 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.2 1.0 GO:0097016 L27 domain binding(GO:0097016)
0.2 0.9 GO:1904315 GABA-gated chloride ion channel activity(GO:0022851) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.2 2.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 1.8 GO:0038191 neuropilin binding(GO:0038191)
0.1 3.6 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1 0.9 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.5 GO:0004859 phospholipase inhibitor activity(GO:0004859) phospholipase A2 inhibitor activity(GO:0019834)
0.1 1.7 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 0.6 GO:0004954 icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)
0.1 1.0 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 0.8 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 1.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 0.1 GO:0001851 complement component C3b binding(GO:0001851)
0.1 3.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.3 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 2.1 GO:0031402 sodium ion binding(GO:0031402)
0.1 3.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.6 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.4 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.2 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099) L-asparagine transmembrane transporter activity(GO:0015182)
0.1 1.0 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.5 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 0.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.3 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1 0.3 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.0 0.4 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.8 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 1.0 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 1.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.2 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 1.2 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.2 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 2.1 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 2.1 GO:0002039 p53 binding(GO:0002039)
0.0 0.4 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 5.7 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.6 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 2.1 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.1 GO:0050347 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 2.2 GO:0017124 SH3 domain binding(GO:0017124)
0.0 2.8 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.0 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.9 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.0 0.4 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.7 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.5 GO:0043621 protein self-association(GO:0043621)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.1 ST_STAT3_PATHWAY STAT3 Pathway
0.1 3.4 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 2.6 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 3.8 PID_CDC42_PATHWAY CDC42 signaling events
0.0 2.7 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 0.6 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 0.5 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 3.7 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.8 PID_INSULIN_PATHWAY Insulin Pathway
0.0 1.0 PID_FOXO_PATHWAY FoxO family signaling
0.0 0.3 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.0 0.2 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 1.7 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 1.0 PID_TNF_PATHWAY TNF receptor signaling pathway
0.0 0.4 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.1 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.2 1.3 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.2 0.6 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 1.0 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.1 1.2 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 1.8 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 3.5 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 1.5 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 4.3 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.1 3.0 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.1 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 0.9 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.1 2.1 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.9 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 1.2 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.4 REACTOME_PD1_SIGNALING Genes involved in PD-1 signaling
0.0 1.8 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME_PEPTIDE_HORMONE_BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 0.6 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 1.3 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.2 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.2 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.5 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.6 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.1 REACTOME_TRIGLYCERIDE_BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 0.3 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.9 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.2 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)