Motif ID: Nkx2-3

Z-value: 0.900


Transcription factors associated with Nkx2-3:

Gene SymbolEntrez IDGene Name
Nkx2-3 ENSMUSG00000044220.12 Nkx2-3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nkx2-3mm10_v2_chr19_+_43612299_436123250.533.6e-04Click!


Activity profile for motif Nkx2-3.

activity profile for motif Nkx2-3


Sorted Z-values histogram for motif Nkx2-3

Sorted Z-values for motif Nkx2-3



Network of associatons between targets according to the STRING database.



First level regulatory network of Nkx2-3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_38783503 15.347 ENSMUST00000159334.1
Etv1
ets variant gene 1
chr12_+_38783455 12.634 ENSMUST00000161980.1
ENSMUST00000160701.1
Etv1

ets variant gene 1

chr6_-_23248264 6.607 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr2_+_73271925 6.205 ENSMUST00000090813.5
Sp9
trans-acting transcription factor 9
chr6_-_6882068 5.911 ENSMUST00000142635.1
ENSMUST00000052609.8
Dlx5

distal-less homeobox 5

chr19_-_59170978 5.425 ENSMUST00000172821.2
Vax1
ventral anterior homeobox containing gene 1
chr12_+_38780284 5.084 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
Etv1


ets variant gene 1


chr12_+_38780817 4.819 ENSMUST00000160856.1
Etv1
ets variant gene 1
chr13_+_83504032 3.499 ENSMUST00000163888.1
ENSMUST00000005722.7
Mef2c

myocyte enhancer factor 2C

chr7_+_144838590 3.442 ENSMUST00000105898.1
Fgf3
fibroblast growth factor 3
chr12_-_56535047 3.294 ENSMUST00000178477.2
Nkx2-1
NK2 homeobox 1
chr19_+_43612299 3.235 ENSMUST00000057178.9
Nkx2-3
NK2 homeobox 3
chr2_+_22622183 3.111 ENSMUST00000028123.3
Gad2
glutamic acid decarboxylase 2
chr1_+_6734827 2.997 ENSMUST00000139838.1
St18
suppression of tumorigenicity 18
chr12_+_38781093 2.965 ENSMUST00000161513.1
Etv1
ets variant gene 1
chr5_+_139543889 2.895 ENSMUST00000174792.1
ENSMUST00000031523.8
Uncx

UNC homeobox

chr3_+_134236483 2.862 ENSMUST00000181904.1
ENSMUST00000053048.9
Cxxc4

CXXC finger 4

chr1_+_6730051 2.859 ENSMUST00000043578.6
ENSMUST00000131467.1
ENSMUST00000150761.1
ENSMUST00000151281.1
St18



suppression of tumorigenicity 18



chr1_+_187997821 2.837 ENSMUST00000027906.6
Esrrg
estrogen-related receptor gamma
chr2_-_166155272 2.775 ENSMUST00000088086.3
Sulf2
sulfatase 2
chr1_+_187997835 2.759 ENSMUST00000110938.1
Esrrg
estrogen-related receptor gamma
chr2_-_166155624 2.674 ENSMUST00000109249.2
Sulf2
sulfatase 2
chr3_-_154330543 2.668 ENSMUST00000184966.1
ENSMUST00000177846.2
Lhx8

LIM homeobox protein 8

chr14_+_75455957 2.527 ENSMUST00000164848.1
Siah3
seven in absentia homolog 3 (Drosophila)
chr2_+_136057927 2.485 ENSMUST00000057503.6
Lamp5
lysosomal-associated membrane protein family, member 5
chr10_-_6980376 2.465 ENSMUST00000105617.1
Ipcef1
interaction protein for cytohesin exchange factors 1
chr3_+_67892189 2.410 ENSMUST00000063263.3
Iqcj
IQ motif containing J
chr12_-_56536895 2.330 ENSMUST00000001536.8
Nkx2-1
NK2 homeobox 1
chr18_+_50030977 2.324 ENSMUST00000145726.1
ENSMUST00000128377.1
Tnfaip8

tumor necrosis factor, alpha-induced protein 8

chr18_+_4920509 2.293 ENSMUST00000126977.1
Svil
supervillin
chr3_+_159839729 2.137 ENSMUST00000068952.5
Wls
wntless homolog (Drosophila)
chr9_-_96437434 2.124 ENSMUST00000070500.2
BC043934
cDNA sequence BC043934
chr2_+_152847993 2.006 ENSMUST00000028969.8
Tpx2
TPX2, microtubule-associated protein homolog (Xenopus laevis)
chr2_-_36104060 1.999 ENSMUST00000112961.3
ENSMUST00000112966.3
Lhx6

LIM homeobox protein 6

chr18_+_4993795 1.974 ENSMUST00000153016.1
Svil
supervillin
chr6_+_15196949 1.969 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
Foxp2



forkhead box P2



chr5_-_5266038 1.961 ENSMUST00000115451.1
ENSMUST00000115452.1
ENSMUST00000131392.1
Cdk14


cyclin-dependent kinase 14


chr3_-_36571952 1.867 ENSMUST00000029270.3
Ccna2
cyclin A2
chr1_-_183147461 1.836 ENSMUST00000171366.1
Disp1
dispatched homolog 1 (Drosophila)
chr6_+_34354119 1.810 ENSMUST00000038406.6
Akr1b8
aldo-keto reductase family 1, member B8
chr4_+_136143497 1.781 ENSMUST00000008016.2
Id3
inhibitor of DNA binding 3
chr12_+_58211772 1.746 ENSMUST00000110671.2
ENSMUST00000044299.2
Sstr1

somatostatin receptor 1

chr6_-_99044414 1.725 ENSMUST00000177507.1
ENSMUST00000123992.1
Foxp1

forkhead box P1

chr9_+_106368594 1.668 ENSMUST00000172306.2
Dusp7
dual specificity phosphatase 7
chr3_-_110143937 1.614 ENSMUST00000051253.3
Ntng1
netrin G1
chr3_+_55782500 1.586 ENSMUST00000075422.4
Mab21l1
mab-21-like 1 (C. elegans)
chr12_+_117843489 1.575 ENSMUST00000021592.9
Cdca7l
cell division cycle associated 7 like
chr10_+_94576254 1.561 ENSMUST00000117929.1
Tmcc3
transmembrane and coiled coil domains 3
chr15_+_92597104 1.544 ENSMUST00000035399.8
Pdzrn4
PDZ domain containing RING finger 4
chr8_-_109251698 1.476 ENSMUST00000079189.3
4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr9_+_34486125 1.473 ENSMUST00000115148.2
ENSMUST00000183580.1
Kirrel3
RP24-225I21.1
kin of IRRE like 3 (Drosophila)
RP24-225I21.1
chr1_-_78968079 1.471 ENSMUST00000049117.5
Gm5830
predicted pseudogene 5830
chr3_-_88410295 1.466 ENSMUST00000056370.7
Pmf1
polyamine-modulated factor 1
chr13_-_114458720 1.442 ENSMUST00000022287.5
Fst
follistatin
chr14_+_59625281 1.428 ENSMUST00000053949.5
Shisa2
shisa homolog 2 (Xenopus laevis)
chr3_-_154328634 1.404 ENSMUST00000167744.1
Lhx8
LIM homeobox protein 8
chr1_+_66321708 1.362 ENSMUST00000114013.1
Map2
microtubule-associated protein 2
chr1_-_193370225 1.310 ENSMUST00000169907.1
Camk1g
calcium/calmodulin-dependent protein kinase I gamma
chr14_-_48667508 1.301 ENSMUST00000144465.1
ENSMUST00000133479.1
ENSMUST00000119070.1
ENSMUST00000152018.1
Otx2



orthodenticle homolog 2 (Drosophila)



chr3_+_137624031 1.277 ENSMUST00000165845.1
Ddit4l
DNA-damage-inducible transcript 4-like
chr11_-_79504078 1.268 ENSMUST00000164465.2
Omg
oligodendrocyte myelin glycoprotein
chr1_+_110099295 1.259 ENSMUST00000134301.1
Cdh7
cadherin 7, type 2
chr19_+_8740712 1.248 ENSMUST00000163172.1
1700092M07Rik
RIKEN cDNA 1700092M07 gene
chr6_-_99266494 1.248 ENSMUST00000113326.2
Foxp1
forkhead box P1
chr1_-_193370260 1.244 ENSMUST00000016323.4
Camk1g
calcium/calmodulin-dependent protein kinase I gamma
chr10_+_56377300 1.229 ENSMUST00000068581.7
Gja1
gap junction protein, alpha 1
chr6_-_138426735 1.226 ENSMUST00000162932.1
Lmo3
LIM domain only 3
chrX_-_23285532 1.215 ENSMUST00000115319.2
Klhl13
kelch-like 13
chr3_+_40800778 1.211 ENSMUST00000169566.1
Plk4
polo-like kinase 4
chr3_-_87174657 1.205 ENSMUST00000159976.1
ENSMUST00000107618.2
Kirrel

kin of IRRE like (Drosophila)

chr10_+_94575257 1.202 ENSMUST00000121471.1
Tmcc3
transmembrane and coiled coil domains 3
chr8_-_48555846 1.200 ENSMUST00000110345.1
ENSMUST00000110343.1
Tenm3

teneurin transmembrane protein 3

chr4_+_127172866 1.179 ENSMUST00000106094.2
Dlgap3
discs, large (Drosophila) homolog-associated protein 3
chr3_+_122419772 1.152 ENSMUST00000029766.4
Bcar3
breast cancer anti-estrogen resistance 3
chr3_+_125404072 1.136 ENSMUST00000173932.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr19_+_23723279 1.119 ENSMUST00000067077.1
Gm9938
predicted gene 9938
chr19_-_15924560 1.099 ENSMUST00000162053.1
Psat1
phosphoserine aminotransferase 1
chr3_-_86548268 1.088 ENSMUST00000077524.3
Mab21l2
mab-21-like 2 (C. elegans)
chr5_+_92897981 1.018 ENSMUST00000113051.2
Shroom3
shroom family member 3
chr12_+_74297474 1.012 ENSMUST00000072100.3
Dbpht2
DNA binding protein with his-thr domain
chr3_+_55461758 0.999 ENSMUST00000070418.4
Dclk1
doublecortin-like kinase 1
chr1_-_37496095 0.974 ENSMUST00000148047.1
ENSMUST00000143636.1
Mgat4a

mannoside acetylglucosaminyltransferase 4, isoenzyme A

chr4_-_36056726 0.961 ENSMUST00000108124.3
Lingo2
leucine rich repeat and Ig domain containing 2
chr4_-_129261394 0.961 ENSMUST00000145261.1
C77080
expressed sequence C77080
chrX_-_48208566 0.944 ENSMUST00000037960.4
Zdhhc9
zinc finger, DHHC domain containing 9
chr4_-_36136463 0.941 ENSMUST00000098151.2
Lingo2
leucine rich repeat and Ig domain containing 2
chr15_+_92051153 0.929 ENSMUST00000169825.1
Cntn1
contactin 1
chr2_+_83724397 0.905 ENSMUST00000028499.4
ENSMUST00000141725.1
ENSMUST00000111740.2
Itgav


integrin alpha V


chr16_-_16829276 0.899 ENSMUST00000023468.5
Spag6
sperm associated antigen 6
chr1_+_66322102 0.890 ENSMUST00000123647.1
Map2
microtubule-associated protein 2
chr3_+_118430299 0.887 ENSMUST00000180774.1
Gm26871
predicted gene, 26871
chr18_+_88971790 0.886 ENSMUST00000023828.7
Rttn
rotatin
chrX_-_48208870 0.876 ENSMUST00000088935.3
Zdhhc9
zinc finger, DHHC domain containing 9
chr11_+_120232921 0.870 ENSMUST00000122148.1
ENSMUST00000044985.7
Bahcc1

BAH domain and coiled-coil containing 1

chr14_-_62454793 0.843 ENSMUST00000128573.1
Gucy1b2
guanylate cyclase 1, soluble, beta 2
chr3_+_125404292 0.839 ENSMUST00000144344.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr1_+_19212054 0.829 ENSMUST00000064976.4
Tfap2b
transcription factor AP-2 beta
chr5_-_98566762 0.802 ENSMUST00000086912.4
1700010H22Rik
RIKEN cDNA 1700010H22 gene
chr2_-_72986716 0.798 ENSMUST00000112062.1
Gm11084
predicted gene 11084
chr1_+_137928100 0.791 ENSMUST00000054333.2
A130050O07Rik
RIKEN cDNA A130050O07 gene
chr18_-_84086379 0.790 ENSMUST00000060303.8
Tshz1
teashirt zinc finger family member 1
chr3_-_126998408 0.781 ENSMUST00000182764.1
ENSMUST00000044443.8
Ank2

ankyrin 2, brain

chr7_-_116198487 0.779 ENSMUST00000181981.1
Plekha7
pleckstrin homology domain containing, family A member 7
chr1_+_72284367 0.752 ENSMUST00000027380.5
ENSMUST00000141783.1
Tmem169

transmembrane protein 169

chr10_+_99263224 0.733 ENSMUST00000020118.4
Dusp6
dual specificity phosphatase 6
chr7_-_116038734 0.685 ENSMUST00000166877.1
Sox6
SRY-box containing gene 6
chr8_-_8639363 0.640 ENSMUST00000152698.1
Efnb2
ephrin B2
chr6_+_54039558 0.630 ENSMUST00000046856.7
Chn2
chimerin (chimaerin) 2
chr2_-_147186389 0.630 ENSMUST00000109970.3
ENSMUST00000067075.5
Nkx2-2

NK2 homeobox 2

chr1_-_126830786 0.621 ENSMUST00000162646.1
Nckap5
NCK-associated protein 5
chr15_-_13173607 0.620 ENSMUST00000036439.4
Cdh6
cadherin 6
chr7_+_101896340 0.612 ENSMUST00000035395.7
ENSMUST00000106973.1
ENSMUST00000144207.1
Anapc15


anaphase prompoting complex C subunit 15


chr15_-_79285502 0.595 ENSMUST00000165408.1
Baiap2l2
BAI1-associated protein 2-like 2
chr15_+_21111452 0.582 ENSMUST00000075132.6
Cdh12
cadherin 12
chr5_+_8893677 0.572 ENSMUST00000003717.8
Abcb4
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chrX_-_93832106 0.570 ENSMUST00000045748.6
Pdk3
pyruvate dehydrogenase kinase, isoenzyme 3
chr8_+_45628176 0.569 ENSMUST00000130850.1
Sorbs2
sorbin and SH3 domain containing 2
chr19_-_53589067 0.558 ENSMUST00000095978.3
Nutf2-ps1
nuclear transport factor 2, pseudogene 1
chr4_+_99955715 0.557 ENSMUST00000102783.4
Pgm2
phosphoglucomutase 2
chr3_+_84952146 0.552 ENSMUST00000029727.7
Fbxw7
F-box and WD-40 domain protein 7
chr2_+_3114220 0.549 ENSMUST00000072955.5
Fam171a1
family with sequence similarity 171, member A1
chr19_+_24875679 0.545 ENSMUST00000073080.5
Gm10053
predicted gene 10053
chr1_-_175688353 0.545 ENSMUST00000104984.1
Chml
choroideremia-like
chr1_+_151571373 0.532 ENSMUST00000148810.1
Fam129a
family with sequence similarity 129, member A
chr1_-_162859684 0.529 ENSMUST00000131058.1
Fmo1
flavin containing monooxygenase 1
chr1_-_126830632 0.526 ENSMUST00000112583.1
ENSMUST00000094609.3
Nckap5

NCK-associated protein 5

chr13_-_113663670 0.519 ENSMUST00000054650.4
Hspb3
heat shock protein 3
chr14_+_25607797 0.514 ENSMUST00000160229.1
Zmiz1
zinc finger, MIZ-type containing 1
chr2_+_181767040 0.491 ENSMUST00000108756.1
Myt1
myelin transcription factor 1
chr2_-_174346712 0.473 ENSMUST00000168292.1
Gm20721
predicted gene, 20721
chr7_-_132576372 0.472 ENSMUST00000084500.6
Oat
ornithine aminotransferase
chr10_-_20725023 0.463 ENSMUST00000020165.7
Pde7b
phosphodiesterase 7B
chr10_-_95673451 0.459 ENSMUST00000099328.1
Anapc15-ps
anaphase prompoting complex C subunit 15, pseudogene
chr13_-_117025505 0.457 ENSMUST00000022239.6
Parp8
poly (ADP-ribose) polymerase family, member 8
chr3_+_102734496 0.455 ENSMUST00000029451.5
Tspan2
tetraspanin 2
chr11_+_6560183 0.449 ENSMUST00000109722.2
Ccm2
cerebral cavernous malformation 2
chr13_+_51408618 0.448 ENSMUST00000087978.3
S1pr3
sphingosine-1-phosphate receptor 3
chr2_+_181767283 0.441 ENSMUST00000108757.2
Myt1
myelin transcription factor 1
chr4_-_59783800 0.440 ENSMUST00000107526.1
ENSMUST00000095063.4
Inip

INTS3 and NABP interacting protein

chr8_+_45627946 0.435 ENSMUST00000145458.1
Sorbs2
sorbin and SH3 domain containing 2
chr6_-_138421379 0.433 ENSMUST00000163065.1
Lmo3
LIM domain only 3
chr6_-_138422898 0.416 ENSMUST00000161450.1
ENSMUST00000163024.1
ENSMUST00000162185.1
Lmo3


LIM domain only 3


chr7_+_101896817 0.399 ENSMUST00000143835.1
Anapc15
anaphase prompoting complex C subunit 15
chr1_-_172027251 0.396 ENSMUST00000138714.1
Vangl2
vang-like 2 (van gogh, Drosophila)
chr1_-_152625212 0.389 ENSMUST00000027760.7
Rgl1
ral guanine nucleotide dissociation stimulator,-like 1
chr8_+_127064022 0.388 ENSMUST00000160272.1
ENSMUST00000079777.5
ENSMUST00000162907.1
Pard3


par-3 (partitioning defective 3) homolog (C. elegans)


chr4_-_45408646 0.385 ENSMUST00000153904.1
ENSMUST00000132815.2
ENSMUST00000107796.1
ENSMUST00000116341.3
Slc25a51



solute carrier family 25, member 51



chr9_-_16378231 0.380 ENSMUST00000082170.5
Fat3
FAT tumor suppressor homolog 3 (Drosophila)
chr12_-_87443800 0.379 ENSMUST00000162961.1
Alkbh1
alkB, alkylation repair homolog 1 (E. coli)
chr5_-_72587544 0.374 ENSMUST00000031124.4
Gm5868
predicted gene 5868
chr19_-_14598031 0.372 ENSMUST00000167776.2
Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chrX_-_136741155 0.370 ENSMUST00000166930.1
ENSMUST00000113095.1
ENSMUST00000155207.1
ENSMUST00000080411.6
ENSMUST00000169418.1
Morf4l2




mortality factor 4 like 2




chrX_+_37126777 0.367 ENSMUST00000016553.4
Nkap
NFKB activating protein
chr19_-_14597983 0.367 ENSMUST00000052011.7
Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chrX_+_101429555 0.367 ENSMUST00000033673.6
Nono
non-POU-domain-containing, octamer binding protein
chr15_+_25773985 0.358 ENSMUST00000125667.1
Myo10
myosin X
chr15_-_98934522 0.356 ENSMUST00000077577.7
Tuba1b
tubulin, alpha 1B
chr11_+_59306920 0.340 ENSMUST00000000128.3
ENSMUST00000108783.3
Wnt9a

wingless-type MMTV integration site 9A

chr15_-_100424208 0.339 ENSMUST00000154331.1
Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr11_+_94328242 0.322 ENSMUST00000021227.5
Ankrd40
ankyrin repeat domain 40
chr18_-_75697639 0.318 ENSMUST00000165559.1
Ctif
CBP80/20-dependent translation initiation factor
chr18_-_66022580 0.315 ENSMUST00000143990.1
Lman1
lectin, mannose-binding, 1
chr13_+_23555023 0.310 ENSMUST00000045301.6
Hist1h1d
histone cluster 1, H1d
chr2_-_67194695 0.308 ENSMUST00000147939.1
Gm13598
predicted gene 13598
chr13_+_93308006 0.303 ENSMUST00000079086.6
Homer1
homer homolog 1 (Drosophila)
chr12_+_100110148 0.300 ENSMUST00000021595.8
Psmc1
protease (prosome, macropain) 26S subunit, ATPase 1
chr15_-_37459327 0.292 ENSMUST00000119730.1
ENSMUST00000120746.1
Ncald

neurocalcin delta

chr15_-_93336800 0.285 ENSMUST00000080299.6
Yaf2
YY1 associated factor 2
chr15_-_100424092 0.283 ENSMUST00000154676.1
Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr3_+_87906842 0.281 ENSMUST00000159492.1
Hdgf
hepatoma-derived growth factor
chr11_-_79962374 0.267 ENSMUST00000108241.1
ENSMUST00000043152.5
Utp6

UTP6, small subunit (SSU) processome component, homolog (yeast)

chr5_-_116288978 0.264 ENSMUST00000050178.6
Ccdc60
coiled-coil domain containing 60
chr12_-_36042476 0.261 ENSMUST00000020896.8
Tspan13
tetraspanin 13
chr7_-_5014645 0.258 ENSMUST00000165320.1
Fiz1
Flt3 interacting zinc finger protein 1
chrX_-_74246534 0.251 ENSMUST00000101454.2
ENSMUST00000033699.6
Flna

filamin, alpha

chr18_-_43477764 0.246 ENSMUST00000057110.9
Eif3j2
eukaryotic translation initiation factor 3, subunit J2
chr12_+_52516077 0.240 ENSMUST00000110725.1
Arhgap5
Rho GTPase activating protein 5
chrX_-_143933089 0.238 ENSMUST00000087313.3
Dcx
doublecortin
chr11_+_94327984 0.238 ENSMUST00000107818.2
ENSMUST00000051221.6
Ankrd40

ankyrin repeat domain 40

chr2_-_32424005 0.237 ENSMUST00000113307.2
Slc25a25
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25
chr9_+_32116040 0.221 ENSMUST00000174641.1
Arhgap32
Rho GTPase activating protein 32
chr17_+_27839974 0.218 ENSMUST00000071006.7
Snrpc
U1 small nuclear ribonucleoprotein C
chrX_-_139871637 0.214 ENSMUST00000033811.7
ENSMUST00000087401.5
Morc4

microrchidia 4

chr7_-_114117761 0.206 ENSMUST00000069449.5
Rras2
related RAS viral (r-ras) oncogene homolog 2
chr2_+_125859134 0.204 ENSMUST00000028636.6
ENSMUST00000125084.1
Galk2

galactokinase 2

chr14_+_4198185 0.201 ENSMUST00000180184.1
Gm2974
predicted gene 2974
chr19_+_5474681 0.200 ENSMUST00000165485.1
ENSMUST00000166253.1
ENSMUST00000167371.1
ENSMUST00000167855.1
ENSMUST00000070118.7
Efemp2




epidermal growth factor-containing fibulin-like extracellular matrix protein 2




chr4_+_140700487 0.194 ENSMUST00000071169.2
Rcc2
regulator of chromosome condensation 2
chr12_+_52699297 0.193 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chr10_-_80421847 0.190 ENSMUST00000156244.1
Tcf3
transcription factor 3
chr1_+_66700831 0.190 ENSMUST00000027157.3
ENSMUST00000113995.1
Rpe

ribulose-5-phosphate-3-epimerase

chr3_-_150073620 0.189 ENSMUST00000057740.5
Rpsa-ps10
ribosomal protein SA, pseudogene 10
chr6_-_148946146 0.187 ENSMUST00000132696.1
Fam60a
family with sequence similarity 60, member A
chr14_+_73237891 0.186 ENSMUST00000044405.6
Lpar6
lysophosphatidic acid receptor 6
chr7_+_123123870 0.182 ENSMUST00000094053.5
Tnrc6a
trinucleotide repeat containing 6a
chrX_-_59568068 0.182 ENSMUST00000119833.1
ENSMUST00000131319.1
Fgf13

fibroblast growth factor 13

chr4_-_131937165 0.180 ENSMUST00000155990.1
Epb4.1
erythrocyte protein band 4.1
chr1_+_40465976 0.179 ENSMUST00000108044.2
ENSMUST00000087983.2
Il18r1

interleukin 18 receptor 1

chr6_+_29859686 0.172 ENSMUST00000134438.1
Ahcyl2
S-adenosylhomocysteine hydrolase-like 2
chr11_+_94044111 0.170 ENSMUST00000132079.1
Spag9
sperm associated antigen 9

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 40.9 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
2.0 5.9 GO:0060166 olfactory pit development(GO:0060166)
1.9 5.6 GO:0021759 globus pallidus development(GO:0021759)
1.4 5.4 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
1.2 3.5 GO:0007521 muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111)
1.1 6.5 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.7 2.1 GO:0061357 Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356) positive regulation of Wnt protein secretion(GO:0061357)
0.7 5.4 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.6 3.1 GO:0006538 glutamate catabolic process(GO:0006538)
0.6 1.8 GO:0016095 polyprenol catabolic process(GO:0016095) terpenoid catabolic process(GO:0016115) primary alcohol catabolic process(GO:0034310)
0.5 3.2 GO:0002317 plasma cell differentiation(GO:0002317)
0.5 2.5 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.5 2.0 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.5 3.4 GO:0030916 otic vesicle formation(GO:0030916)
0.5 5.9 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.4 1.7 GO:0003347 epicardial cell to mesenchymal cell transition(GO:0003347)
0.3 1.3 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.3 0.6 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.3 0.9 GO:0038044 negative regulation of receptor biosynthetic process(GO:0010871) transforming growth factor-beta secretion(GO:0038044)
0.3 3.0 GO:0061470 interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619)
0.3 1.5 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.3 0.8 GO:0097274 urea homeostasis(GO:0097274)
0.3 0.8 GO:0060023 soft palate development(GO:0060023)
0.3 2.8 GO:0060539 diaphragm development(GO:0060539)
0.2 0.7 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.2 1.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.2 1.9 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.2 1.2 GO:0098535 positive regulation of centriole replication(GO:0046601) de novo centriole assembly(GO:0098535)
0.2 1.8 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 1.5 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.1 2.9 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 0.6 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 0.8 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.6 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.1 0.3 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.1 0.5 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.1 5.7 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 0.6 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 0.4 GO:0002101 tRNA wobble cytosine modification(GO:0002101) oxidative single-stranded DNA demethylation(GO:0035552)
0.1 1.0 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.8 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1 1.7 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.1 0.6 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.1 1.0 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 0.7 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 0.6 GO:0097264 self proteolysis(GO:0097264)
0.1 1.8 GO:0030903 notochord development(GO:0030903)
0.1 0.1 GO:0060018 astrocyte fate commitment(GO:0060018)
0.1 0.5 GO:0007296 vitellogenesis(GO:0007296)
0.1 2.1 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.1 0.6 GO:0019388 galactose catabolic process(GO:0019388)
0.1 0.3 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.1 0.5 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 0.5 GO:0034214 protein hexamerization(GO:0034214)
0.1 0.1 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.1 0.4 GO:0003383 apical constriction(GO:0003383)
0.1 0.5 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 1.3 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.1 0.2 GO:0071351 interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.1 1.1 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 1.1 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.1 2.8 GO:0032611 interleukin-1 beta production(GO:0032611)
0.1 0.4 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1 1.7 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.1 2.3 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.1 0.2 GO:0006012 galactose metabolic process(GO:0006012)
0.0 1.9 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.2 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.2 GO:0019323 pentose catabolic process(GO:0019323)
0.0 0.1 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.0 2.0 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.4 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 2.1 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.6 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 4.2 GO:0030326 embryonic limb morphogenesis(GO:0030326) embryonic appendage morphogenesis(GO:0035113)
0.0 0.1 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 1.2 GO:0007588 excretion(GO:0007588)
0.0 0.3 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.1 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.1 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.3 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.3 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.0 3.2 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 1.0 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.0 1.2 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.2 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
0.0 0.1 GO:0070171 negative regulation of odontogenesis(GO:0042483) negative regulation of tooth mineralization(GO:0070171)
0.0 0.2 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.2 GO:0014823 response to activity(GO:0014823)
0.0 0.1 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.0 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 1.8 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.0 0.4 GO:0010842 retina layer formation(GO:0010842)
0.0 0.4 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.4 GO:0030851 granulocyte differentiation(GO:0030851)
0.0 0.1 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.1 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 1.0 GO:0006487 protein N-linked glycosylation(GO:0006487)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.4 2.5 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.4 2.0 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.3 0.9 GO:0034684 integrin alphav-beta5 complex(GO:0034684)
0.3 1.9 GO:0001940 male pronucleus(GO:0001940)
0.3 2.0 GO:0005818 aster(GO:0005818)
0.3 2.3 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.2 1.5 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.2 1.2 GO:0098536 deuterosome(GO:0098536)
0.2 1.8 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 0.6 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.6 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.5 GO:0060187 cell pole(GO:0060187)
0.1 5.2 GO:0043034 costamere(GO:0043034)
0.1 1.2 GO:0005916 fascia adherens(GO:0005916)
0.1 0.5 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.4 GO:0070876 SOSS complex(GO:0070876)
0.1 0.9 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 0.6 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.3 GO:0031523 Myb complex(GO:0031523)
0.1 0.6 GO:0071439 clathrin complex(GO:0071439)
0.1 2.4 GO:0060077 inhibitory synapse(GO:0060077)
0.1 2.1 GO:0032590 dendrite membrane(GO:0032590)
0.1 0.6 GO:0005915 zonula adherens(GO:0005915)
0.0 0.4 GO:0033269 internode region of axon(GO:0033269)
0.0 0.4 GO:0042382 paraspeckles(GO:0042382)
0.0 0.3 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.8 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 1.0 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.3 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.3 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.1 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.0 1.7 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.2 GO:0000243 commitment complex(GO:0000243)
0.0 0.3 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 2.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.6 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 4.4 GO:0016607 nuclear speck(GO:0016607)
0.0 0.1 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 1.8 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.8 GO:0036064 ciliary basal body(GO:0036064)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 5.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.9 11.0 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.6 1.7 GO:0004994 somatostatin receptor activity(GO:0004994)
0.4 3.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.4 1.8 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.3 1.2 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075) gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.3 9.4 GO:0071837 HMG box domain binding(GO:0071837)
0.3 2.0 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.3 2.3 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.3 5.6 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.2 2.5 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.2 1.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2 2.0 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.2 0.9 GO:0019960 C-X3-C chemokine binding(GO:0019960) neuregulin binding(GO:0038132)
0.2 2.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 3.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.6 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 0.6 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 1.8 GO:0015197 peptide transporter activity(GO:0015197)
0.1 1.4 GO:0048185 activin binding(GO:0048185)
0.1 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.6 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 1.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 0.6 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 33.9 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 0.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.6 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 1.6 GO:0008483 transaminase activity(GO:0008483)
0.1 3.8 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.1 0.4 GO:0043734 DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.1 0.5 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.2 GO:0004335 galactokinase activity(GO:0004335)
0.1 0.8 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.4 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 1.8 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 2.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 2.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 12.3 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1 0.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 4.5 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.1 0.4 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.8 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.3 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 1.7 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.6 GO:0001159 core promoter proximal region DNA binding(GO:0001159)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 4.1 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.3 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.5 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 5.2 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 1.1 GO:0017022 myosin binding(GO:0017022)
0.0 0.1 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.0 0.0 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.7 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.6 GO:0030507 spectrin binding(GO:0030507)
0.0 0.7 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.7 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.2 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 1.5 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.0 0.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.0 GO:0015166 polyol transmembrane transporter activity(GO:0015166) glycerol transmembrane transporter activity(GO:0015168) glycerol channel activity(GO:0015254)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 41.1 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 1.9 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 5.9 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 5.3 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 3.5 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 2.5 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 2.9 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.1 2.0 PID_AURORA_A_PATHWAY Aurora A signaling
0.1 0.9 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.0 1.6 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 1.2 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 2.3 PID_LKB1_PATHWAY LKB1 signaling events
0.0 1.2 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 3.0 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 1.4 PID_BMP_PATHWAY BMP receptor signaling
0.0 1.2 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 1.2 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.7 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.6 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 0.4 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.0 0.4 PID_S1P_S1P3_PATHWAY S1P3 pathway
0.0 3.4 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.3 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 0.4 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 0.4 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 0.6 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.3 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.0 0.9 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 0.4 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.0 0.2 PID_IL23_PATHWAY IL23-mediated signaling events
0.0 0.4 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.6 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.3 PID_TCPTP_PATHWAY Signaling events mediated by TCPTP
0.0 0.6 PID_ERBB1_DOWNSTREAM_PATHWAY ErbB1 downstream signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.4 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.2 6.0 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.1 3.1 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 1.9 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 1.2 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.1 1.6 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.1 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.1 0.9 REACTOME_PECAM1_INTERACTIONS Genes involved in PECAM1 interactions
0.1 2.0 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.6 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 2.4 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.6 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.4 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.9 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.7 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.3 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.2 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 1.9 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.4 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.3 REACTOME_SIGNALING_BY_NOTCH1 Genes involved in Signaling by NOTCH1
0.0 0.9 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.3 REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.2 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.3 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)