Motif ID: Prop1

Z-value: 0.871


Transcription factors associated with Prop1:

Gene SymbolEntrez IDGene Name
Prop1 ENSMUSG00000044542.3 Prop1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Prop1mm10_v2_chr11_-_50953745_50953768-0.241.3e-01Click!


Activity profile for motif Prop1.

activity profile for motif Prop1


Sorted Z-values histogram for motif Prop1

Sorted Z-values for motif Prop1



Network of associatons between targets according to the STRING database.



First level regulatory network of Prop1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_45470201 8.016 ENSMUST00000079390.6
Lin28b
lin-28 homolog B (C. elegans)
chr13_+_94875600 6.699 ENSMUST00000022195.10
Otp
orthopedia homolog (Drosophila)
chr1_+_107511416 5.089 ENSMUST00000009356.4
Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr3_+_146121655 4.434 ENSMUST00000039450.4
Mcoln3
mucolipin 3
chr16_-_16829276 4.224 ENSMUST00000023468.5
Spag6
sperm associated antigen 6
chr12_+_79297345 3.938 ENSMUST00000079533.5
ENSMUST00000171210.1
Rad51b

RAD51 homolog B

chr15_-_56694525 3.876 ENSMUST00000050544.7
Has2
hyaluronan synthase 2
chr17_+_27556613 3.696 ENSMUST00000117600.1
ENSMUST00000114888.3
Hmga1

high mobility group AT-hook 1

chr17_+_27556668 3.651 ENSMUST00000117254.1
ENSMUST00000118570.1
Hmga1

high mobility group AT-hook 1

chr1_+_6734827 3.633 ENSMUST00000139838.1
St18
suppression of tumorigenicity 18
chr14_+_75455957 3.525 ENSMUST00000164848.1
Siah3
seven in absentia homolog 3 (Drosophila)
chr17_+_27556641 3.440 ENSMUST00000119486.1
ENSMUST00000118599.1
Hmga1

high mobility group AT-hook 1

chr14_-_48667508 3.143 ENSMUST00000144465.1
ENSMUST00000133479.1
ENSMUST00000119070.1
ENSMUST00000152018.1
Otx2



orthodenticle homolog 2 (Drosophila)



chr3_+_94377432 3.123 ENSMUST00000107292.1
Rorc
RAR-related orphan receptor gamma
chr18_-_66860458 3.079 ENSMUST00000057942.2
Mc4r
melanocortin 4 receptor
chr18_-_13972617 3.028 ENSMUST00000025288.7
Zfp521
zinc finger protein 521
chr14_-_40893222 3.018 ENSMUST00000096000.3
Sh2d4b
SH2 domain containing 4B
chr3_-_141982224 2.995 ENSMUST00000029948.8
Bmpr1b
bone morphogenetic protein receptor, type 1B
chr2_+_61804453 2.934 ENSMUST00000048934.8
Tbr1
T-box brain gene 1
chr10_-_64090241 2.846 ENSMUST00000133588.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr4_-_110292719 2.840 ENSMUST00000106601.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr10_-_64090265 2.809 ENSMUST00000105439.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr3_+_94377505 2.734 ENSMUST00000098877.2
Rorc
RAR-related orphan receptor gamma
chr4_+_3940747 2.685 ENSMUST00000119403.1
Chchd7
coiled-coil-helix-coiled-coil-helix domain containing 7
chr2_-_112480817 2.668 ENSMUST00000099589.2
Chrm5
cholinergic receptor, muscarinic 5
chr18_+_74442551 2.569 ENSMUST00000121875.1
Myo5b
myosin VB
chr4_+_109978004 2.507 ENSMUST00000061187.3
Dmrta2
doublesex and mab-3 related transcription factor like family A2
chr18_-_62741387 2.501 ENSMUST00000097557.3
Spink13
serine peptidase inhibitor, Kazal type 13
chr1_+_187997835 2.451 ENSMUST00000110938.1
Esrrg
estrogen-related receptor gamma
chr1_+_187997821 2.393 ENSMUST00000027906.6
Esrrg
estrogen-related receptor gamma
chr9_-_39604124 2.331 ENSMUST00000042485.4
ENSMUST00000141370.1
AW551984

expressed sequence AW551984

chr3_+_37639945 2.324 ENSMUST00000108109.1
ENSMUST00000038569.1
Spry1

sprouty homolog 1 (Drosophila)

chr9_-_73968901 2.288 ENSMUST00000184666.1
Unc13c
unc-13 homolog C (C. elegans)
chr3_+_37639985 2.281 ENSMUST00000108107.1
Spry1
sprouty homolog 1 (Drosophila)
chr4_+_15881255 2.252 ENSMUST00000029876.1
Calb1
calbindin 1
chr1_-_169531343 2.231 ENSMUST00000028000.7
Nuf2
NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr4_-_41517326 2.085 ENSMUST00000030152.6
ENSMUST00000095126.4
1110017D15Rik

RIKEN cDNA 1110017D15 gene

chr14_+_74640840 2.053 ENSMUST00000036653.3
Htr2a
5-hydroxytryptamine (serotonin) receptor 2A
chr1_-_169531447 1.999 ENSMUST00000111368.1
Nuf2
NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr7_+_100159241 1.987 ENSMUST00000032967.3
Lipt2
lipoyl(octanoyl) transferase 2 (putative)
chr14_+_73237891 1.929 ENSMUST00000044405.6
Lpar6
lysophosphatidic acid receptor 6
chr9_-_64172879 1.884 ENSMUST00000176299.1
ENSMUST00000130127.1
ENSMUST00000176794.1
ENSMUST00000177045.1
Zwilch



zwilch kinetochore protein



chr9_-_121857952 1.819 ENSMUST00000060251.6
Higd1a
HIG1 domain family, member 1A
chr19_+_38395980 1.806 ENSMUST00000054098.2
Slc35g1
solute carrier family 35, member G1
chr1_-_186117251 1.803 ENSMUST00000045388.7
Lyplal1
lysophospholipase-like 1
chr2_-_67194695 1.803 ENSMUST00000147939.1
Gm13598
predicted gene 13598
chr12_+_38783455 1.767 ENSMUST00000161980.1
ENSMUST00000160701.1
Etv1

ets variant gene 1

chr17_-_35027909 1.732 ENSMUST00000040151.2
Sapcd1
suppressor APC domain containing 1
chr13_-_3918157 1.687 ENSMUST00000091853.4
Net1
neuroepithelial cell transforming gene 1
chr16_+_38346986 1.685 ENSMUST00000050273.8
ENSMUST00000120495.1
ENSMUST00000119704.1
Cox17

Gm21987
cytochrome c oxidase assembly protein 17

predicted gene 21987
chr10_-_109009055 1.683 ENSMUST00000156979.1
Syt1
synaptotagmin I
chr5_-_87482258 1.664 ENSMUST00000079811.6
ENSMUST00000144144.1
Ugt2a1

UDP glucuronosyltransferase 2 family, polypeptide A1

chr4_+_105789869 1.654 ENSMUST00000184254.1
Gm12728
predicted gene 12728
chr2_-_72986716 1.652 ENSMUST00000112062.1
Gm11084
predicted gene 11084
chr2_+_20737306 1.576 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4

enhancer trap locus 4

chr17_+_20570362 1.535 ENSMUST00000095633.3
Gm5145
predicted pseudogene 5145
chr8_-_106573461 1.516 ENSMUST00000073722.5
Gm10073
predicted pseudogene 10073
chr5_-_16731074 1.468 ENSMUST00000073014.5
Gm8991
predicted pseudogene 8991
chr2_+_167777467 1.468 ENSMUST00000139927.1
ENSMUST00000127441.1
Gm14321

predicted gene 14321

chr4_+_126046903 1.464 ENSMUST00000030675.7
Mrps15
mitochondrial ribosomal protein S15
chr9_+_66946057 1.402 ENSMUST00000040917.7
ENSMUST00000127896.1
Rps27l

ribosomal protein S27-like

chr1_-_119504736 1.371 ENSMUST00000004565.8
Ralb
v-ral simian leukemia viral oncogene homolog B (ras related)
chrX_-_134541847 1.340 ENSMUST00000054213.4
Timm8a1
translocase of inner mitochondrial membrane 8A1
chr12_+_111971545 1.297 ENSMUST00000079009.5
Tdrd9
tudor domain containing 9
chr12_-_55014329 1.283 ENSMUST00000172875.1
Baz1a
bromodomain adjacent to zinc finger domain 1A
chr9_-_8134294 1.274 ENSMUST00000037397.6
AK129341
cDNA sequence AK129341
chr2_-_174346712 1.258 ENSMUST00000168292.1
Gm20721
predicted gene, 20721
chr3_-_10331358 1.223 ENSMUST00000065938.8
ENSMUST00000118410.1
Impa1

inositol (myo)-1(or 4)-monophosphatase 1

chr4_-_134767940 1.215 ENSMUST00000037828.6
Ldlrap1
low density lipoprotein receptor adaptor protein 1
chr7_+_62476306 1.175 ENSMUST00000097132.3
Atp5l-ps1
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit g, pseudogene 1
chr5_-_123666682 1.169 ENSMUST00000149410.1
Clip1
CAP-GLY domain containing linker protein 1
chr12_-_57546121 1.157 ENSMUST00000044380.6
Foxa1
forkhead box A1
chr14_-_7483762 1.133 ENSMUST00000164366.1
Gm3752
predicted gene 3752
chr14_+_74735641 1.105 ENSMUST00000177283.1
Esd
esterase D/formylglutathione hydrolase
chr9_-_71163224 1.102 ENSMUST00000074465.2
Aqp9
aquaporin 9
chr5_-_104456467 1.097 ENSMUST00000069263.4
Gm10047
predicted gene 10047
chr4_+_95557494 1.093 ENSMUST00000079223.4
ENSMUST00000177394.1
Fggy

FGGY carbohydrate kinase domain containing

chr4_+_5724304 1.086 ENSMUST00000108380.1
Fam110b
family with sequence similarity 110, member B
chr8_+_127447669 1.084 ENSMUST00000159511.1
Pard3
par-3 (partitioning defective 3) homolog (C. elegans)
chr2_+_14873656 1.075 ENSMUST00000114718.1
ENSMUST00000114719.1
Cacnb2

calcium channel, voltage-dependent, beta 2 subunit

chr11_-_30268169 1.072 ENSMUST00000006629.7
Sptbn1
spectrin beta, non-erythrocytic 1
chr7_+_126695355 1.058 ENSMUST00000130498.1
Bola2
bolA-like 2 (E. coli)
chr2_-_71546745 1.008 ENSMUST00000024159.6
Dlx2
distal-less homeobox 2
chrX_-_103186618 1.002 ENSMUST00000121720.1
Nap1l2
nucleosome assembly protein 1-like 2
chr5_+_15516489 0.976 ENSMUST00000178227.1
Gm21847
predicted gene, 21847
chr5_+_31613939 0.954 ENSMUST00000031024.7
Mrpl33
mitochondrial ribosomal protein L33
chr1_-_24005608 0.951 ENSMUST00000027338.3
1110058L19Rik
RIKEN cDNA 1110058L19 gene
chr19_-_23273893 0.935 ENSMUST00000087556.5
Smc5
structural maintenance of chromosomes 5
chr11_+_101442298 0.876 ENSMUST00000077856.6
Rpl27
ribosomal protein L27
chr15_+_99006056 0.870 ENSMUST00000079818.3
Gm8973
predicted gene 8973
chr3_+_136670076 0.863 ENSMUST00000070198.7
Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr6_-_34317442 0.858 ENSMUST00000154655.1
ENSMUST00000102980.4
Akr1b3

aldo-keto reductase family 1, member B3 (aldose reductase)

chr16_-_45693658 0.858 ENSMUST00000114562.2
ENSMUST00000036617.7
Tmprss7

transmembrane serine protease 7

chr11_-_59163696 0.851 ENSMUST00000137433.1
ENSMUST00000054523.5
Iba57

IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)

chr11_-_113684155 0.848 ENSMUST00000120194.1
Fam104a
family with sequence similarity 104, member A
chr3_+_32515295 0.843 ENSMUST00000029203.7
Zfp639
zinc finger protein 639
chrX_-_59166080 0.821 ENSMUST00000119306.1
Fgf13
fibroblast growth factor 13
chr6_+_49367739 0.816 ENSMUST00000060561.8
ENSMUST00000121903.1
ENSMUST00000134786.1
Fam221a


family with sequence similarity 221, member A


chr1_-_171240055 0.813 ENSMUST00000131286.1
Ndufs2
NADH dehydrogenase (ubiquinone) Fe-S protein 2
chr13_+_94788873 0.795 ENSMUST00000046644.5
Tbca
tubulin cofactor A
chr3_-_90213577 0.795 ENSMUST00000170122.2
Rps27
ribosomal protein S27
chr3_+_103739366 0.786 ENSMUST00000106852.1
Gm10964
predicted gene 10964
chr16_-_8672145 0.784 ENSMUST00000008537.8
Carhsp1
calcium regulated heat stable protein 1
chr9_+_64281575 0.779 ENSMUST00000034964.6
Tipin
timeless interacting protein
chr8_-_8639363 0.775 ENSMUST00000152698.1
Efnb2
ephrin B2
chr11_-_99230998 0.769 ENSMUST00000103133.3
Smarce1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
chr17_+_56613392 0.767 ENSMUST00000080492.5
Rpl36
ribosomal protein L36
chr2_-_94438081 0.767 ENSMUST00000028617.6
Api5
apoptosis inhibitor 5
chr3_-_84155762 0.753 ENSMUST00000047368.6
Mnd1
meiotic nuclear divisions 1 homolog (S. cerevisiae)
chrX_-_75578188 0.732 ENSMUST00000033545.5
Rab39b
RAB39B, member RAS oncogene family
chr14_+_57999305 0.727 ENSMUST00000180534.1
3110083C13Rik
RIKEN cDNA 3110083C13 gene
chr3_+_14578609 0.725 ENSMUST00000029069.6
ENSMUST00000165922.2
E2f5

E2F transcription factor 5

chr18_-_43477764 0.722 ENSMUST00000057110.9
Eif3j2
eukaryotic translation initiation factor 3, subunit J2
chr17_-_47611449 0.721 ENSMUST00000024783.8
Bysl
bystin-like
chr4_+_41348996 0.718 ENSMUST00000072866.5
ENSMUST00000108060.3
Ubap1

ubiquitin-associated protein 1

chr10_+_80141457 0.714 ENSMUST00000105367.1
Atp5d
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr14_-_6973818 0.700 ENSMUST00000166618.1
Gm6356
predicted gene 6356
chr16_-_64771146 0.689 ENSMUST00000076991.6
4930453N24Rik
RIKEN cDNA 4930453N24 gene
chr9_-_114982739 0.672 ENSMUST00000053150.5
Gm9846
predicted gene 9846
chr16_-_55283237 0.672 ENSMUST00000036412.3
Zpld1
zona pellucida like domain containing 1
chr3_-_59220150 0.657 ENSMUST00000170388.1
P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr11_+_101087277 0.650 ENSMUST00000107302.1
ENSMUST00000107303.3
ENSMUST00000017945.8
ENSMUST00000149597.1
Mlx



MAX-like protein X



chr1_-_85598796 0.642 ENSMUST00000093508.6
Sp110
Sp110 nuclear body protein
chr12_-_84617326 0.632 ENSMUST00000021666.4
Abcd4
ATP-binding cassette, sub-family D (ALD), member 4
chr14_-_54517353 0.625 ENSMUST00000023873.5
Prmt5
protein arginine N-methyltransferase 5
chr4_+_32623985 0.617 ENSMUST00000108178.1
Casp8ap2
caspase 8 associated protein 2
chr15_+_76343504 0.615 ENSMUST00000023210.6
Cyc1
cytochrome c-1
chr8_-_85432841 0.613 ENSMUST00000047749.5
4921524J17Rik
RIKEN cDNA 4921524J17 gene
chrX_+_170010744 0.609 ENSMUST00000178789.1
Gm21887
predicted gene, 21887
chr17_+_78491549 0.608 ENSMUST00000079363.4
Gm10093
predicted pseudogene 10093
chr14_+_73173825 0.600 ENSMUST00000166875.1
Rcbtb2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr6_+_11925869 0.596 ENSMUST00000115510.1
ENSMUST00000115511.2
ENSMUST00000090632.4
Phf14


PHD finger protein 14


chr7_-_34655500 0.594 ENSMUST00000032709.1
Kctd15
potassium channel tetramerisation domain containing 15
chr5_+_92137896 0.577 ENSMUST00000031355.6
Uso1
USO1 vesicle docking factor
chr4_-_119492563 0.576 ENSMUST00000049994.7
Rimkla
ribosomal modification protein rimK-like family member A
chr7_+_101321079 0.565 ENSMUST00000032927.7
Stard10
START domain containing 10
chr13_+_24327415 0.552 ENSMUST00000167746.1
Cmah
cytidine monophospho-N-acetylneuraminic acid hydroxylase
chr12_+_76837408 0.550 ENSMUST00000041008.9
Fntb
farnesyltransferase, CAAX box, beta
chr2_-_37647199 0.550 ENSMUST00000028279.3
Strbp
spermatid perinuclear RNA binding protein
chr18_+_60774675 0.540 ENSMUST00000118551.1
Rps14
ribosomal protein S14
chr12_+_9029982 0.521 ENSMUST00000085741.1
Ttc32
tetratricopeptide repeat domain 32
chr5_-_100674230 0.519 ENSMUST00000031262.7
Coq2
coenzyme Q2 homolog, prenyltransferase (yeast)
chr18_+_75000469 0.516 ENSMUST00000079716.5
Rpl17
ribosomal protein L17
chr2_-_86347764 0.513 ENSMUST00000099894.2
Olfr1055
olfactory receptor 1055
chr5_+_42067960 0.503 ENSMUST00000087332.4
Gm16223
predicted gene 16223
chr7_+_126976338 0.492 ENSMUST00000032920.3
Cdipt
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr14_-_5633028 0.487 ENSMUST00000170469.1
Gm8265
predicted gene 8265
chr13_-_100108337 0.485 ENSMUST00000180822.1
BC001981
cDNA sequence BC001981
chr8_-_84969412 0.484 ENSMUST00000147812.1
Rnaseh2a
ribonuclease H2, large subunit
chr9_+_118478344 0.482 ENSMUST00000035020.8
Eomes
eomesodermin homolog (Xenopus laevis)
chr18_+_3382979 0.465 ENSMUST00000025073.5
Cul2
cullin 2
chr5_-_90223923 0.455 ENSMUST00000118816.1
ENSMUST00000048363.7
Cox18

cytochrome c oxidase assembly protein 18

chr9_+_64173364 0.435 ENSMUST00000034966.7
Rpl4
ribosomal protein L4
chrY_+_13252442 0.431 ENSMUST00000178599.1
Gm21440
predicted gene, 21440
chr3_-_67515487 0.426 ENSMUST00000178314.1
ENSMUST00000054825.4
Rarres1

retinoic acid receptor responder (tazarotene induced) 1

chr18_+_60774510 0.414 ENSMUST00000025511.3
Rps14
ribosomal protein S14
chr11_-_17953861 0.413 ENSMUST00000076661.6
Etaa1
Ewing's tumor-associated antigen 1
chr12_+_59129720 0.402 ENSMUST00000175912.1
ENSMUST00000176892.1
Ctage5

CTAGE family, member 5

chrY_+_90785442 0.399 ENSMUST00000177591.1
ENSMUST00000177671.1
ENSMUST00000179077.1
Erdr1


erythroid differentiation regulator 1


chr2_+_150909565 0.392 ENSMUST00000028948.4
Gins1
GINS complex subunit 1 (Psf1 homolog)
chr9_+_75051977 0.385 ENSMUST00000170310.1
ENSMUST00000166549.1
Arpp19

cAMP-regulated phosphoprotein 19

chr13_+_67833235 0.374 ENSMUST00000060609.7
Gm10037
predicted gene 10037
chr4_+_141444654 0.373 ENSMUST00000006377.6
Zbtb17
zinc finger and BTB domain containing 17
chrM_+_7759 0.364 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr3_+_87906842 0.360 ENSMUST00000159492.1
Hdgf
hepatoma-derived growth factor
chr12_+_59129757 0.352 ENSMUST00000069430.8
ENSMUST00000177370.1
Ctage5

CTAGE family, member 5

chr3_-_146108047 0.348 ENSMUST00000160285.1
Wdr63
WD repeat domain 63
chr4_-_14826582 0.337 ENSMUST00000117268.1
Otud6b
OTU domain containing 6B
chr3_-_41742471 0.335 ENSMUST00000026866.8
Sclt1
sodium channel and clathrin linker 1
chr1_+_37872206 0.325 ENSMUST00000041621.3
Lipt1
lipoyltransferase 1
chr7_-_132852606 0.323 ENSMUST00000120425.1
Mettl10
methyltransferase like 10
chr1_+_24005505 0.301 ENSMUST00000181961.1
Gm26524
predicted gene, 26524
chr7_-_132852657 0.293 ENSMUST00000033257.8
Mettl10
methyltransferase like 10
chr16_+_4741543 0.293 ENSMUST00000120232.1
Hmox2
heme oxygenase (decycling) 2
chr6_-_83121385 0.281 ENSMUST00000146328.1
ENSMUST00000113936.3
ENSMUST00000032111.4
Wbp1


WW domain binding protein 1


chr4_+_5644084 0.265 ENSMUST00000054857.6
Fam110b
family with sequence similarity 110, member B
chr3_+_88142536 0.257 ENSMUST00000107558.2
ENSMUST00000107559.2
Mef2d

myocyte enhancer factor 2D

chr12_+_85110833 0.255 ENSMUST00000053811.8
Dlst
dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
chr3_-_79145875 0.248 ENSMUST00000118340.1
Rapgef2
Rap guanine nucleotide exchange factor (GEF) 2
chr2_+_158666690 0.231 ENSMUST00000103116.3
Ppp1r16b
protein phosphatase 1, regulatory (inhibitor) subunit 16B
chr5_+_115279666 0.227 ENSMUST00000040421.4
Coq5
coenzyme Q5 homolog, methyltransferase (yeast)
chr1_+_24177610 0.219 ENSMUST00000054588.8
Col9a1
collagen, type IX, alpha 1
chr1_+_37872333 0.216 ENSMUST00000142670.1
Lipt1
lipoyltransferase 1
chr14_-_6219210 0.211 ENSMUST00000177670.1
ENSMUST00000168480.3
Gm21560

predicted gene, 21560

chr1_+_72307413 0.185 ENSMUST00000027379.8
Xrcc5
X-ray repair complementing defective repair in Chinese hamster cells 5
chr17_+_64600702 0.181 ENSMUST00000086723.3
Man2a1
mannosidase 2, alpha 1
chr17_-_24073479 0.180 ENSMUST00000017090.5
Kctd5
potassium channel tetramerisation domain containing 5
chr4_+_102430047 0.157 ENSMUST00000172616.1
Pde4b
phosphodiesterase 4B, cAMP specific
chrM_+_2743 0.154 ENSMUST00000082392.1
mt-Nd1
mitochondrially encoded NADH dehydrogenase 1
chr1_-_127840290 0.150 ENSMUST00000061512.2
Map3k19
mitogen-activated protein kinase kinase kinase 19
chr12_-_116262946 0.145 ENSMUST00000039349.6
Wdr60
WD repeat domain 60
chr14_-_57999236 0.141 ENSMUST00000022543.8
Micu2
mitochondrial calcium uptake 2
chr13_-_4609122 0.126 ENSMUST00000110691.3
ENSMUST00000091848.5
Akr1e1

aldo-keto reductase family 1, member E1

chr9_+_119341294 0.120 ENSMUST00000039784.5
Acaa1a
acetyl-Coenzyme A acyltransferase 1A
chr5_+_114130386 0.115 ENSMUST00000031587.6
Ung
uracil DNA glycosylase
chr9_+_106821874 0.109 ENSMUST00000159645.1
Vprbp
Vpr (HIV-1) binding protein
chr10_+_96616998 0.105 ENSMUST00000038377.7
Btg1
B cell translocation gene 1, anti-proliferative
chr16_-_29541483 0.098 ENSMUST00000057018.8
ENSMUST00000182627.1
Atp13a4

ATPase type 13A4

chr2_+_125136692 0.093 ENSMUST00000099452.2
Ctxn2
cortexin 2
chr6_+_37870786 0.072 ENSMUST00000120428.1
ENSMUST00000031859.7
Trim24

tripartite motif-containing 24


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.9 GO:1900623 positive regulation of keratinocyte proliferation(GO:0010838) regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.9 4.6 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.9 8.0 GO:0010587 miRNA catabolic process(GO:0010587)
0.8 3.1 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.7 3.0 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.7 5.9 GO:0072615 interleukin-17 secretion(GO:0072615)
0.7 3.5 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.7 2.0 GO:0009106 lipoate metabolic process(GO:0009106)
0.7 3.9 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.6 3.1 GO:0002024 diet induced thermogenesis(GO:0002024)
0.6 2.9 GO:0001661 conditioned taste aversion(GO:0001661) amygdala development(GO:0021764)
0.6 1.7 GO:1904959 regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959)
0.5 2.7 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.5 2.1 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.5 2.5 GO:0060467 negative regulation of fertilization(GO:0060467)
0.5 6.7 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.5 2.3 GO:0072235 distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235)
0.4 2.6 GO:0032439 endosome localization(GO:0032439)
0.4 1.2 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.4 1.2 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743) alveolar secondary septum development(GO:0061144)
0.4 5.7 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.4 1.8 GO:1990034 calcium ion export from cell(GO:1990034)
0.4 1.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.3 1.0 GO:0061075 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.3 2.3 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.3 1.7 GO:0052695 cellular glucuronidation(GO:0052695)
0.3 0.9 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.3 3.6 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.3 1.8 GO:0098734 protein depalmitoylation(GO:0002084) negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005) macromolecule depalmitoylation(GO:0098734)
0.3 1.2 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.3 0.9 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) regulation of connective tissue replacement(GO:1905203)
0.3 0.9 GO:0006059 hexitol metabolic process(GO:0006059) alditol biosynthetic process(GO:0019401)
0.3 1.1 GO:0046294 formaldehyde catabolic process(GO:0046294)
0.3 1.4 GO:0060178 regulation of exocyst localization(GO:0060178)
0.3 2.3 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.2 1.7 GO:0032782 bile acid secretion(GO:0032782)
0.2 10.9 GO:0006284 base-excision repair(GO:0006284)
0.2 0.7 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.2 1.3 GO:0034587 piRNA metabolic process(GO:0034587)
0.2 1.7 GO:0005513 detection of calcium ion(GO:0005513)
0.2 0.8 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.2 0.6 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.2 0.6 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.2 1.1 GO:0003383 apical constriction(GO:0003383)
0.2 1.8 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.2 1.0 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.2 2.7 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.2 0.5 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.2 0.8 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.2 1.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 0.5 GO:0018343 protein farnesylation(GO:0018343)
0.1 3.2 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.6 GO:0060161 histone H4-R3 methylation(GO:0043985) positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.1 0.6 GO:0036337 Fas signaling pathway(GO:0036337)
0.1 0.6 GO:0033762 response to glucagon(GO:0033762)
0.1 0.8 GO:0098909 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.1 4.2 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.1 0.8 GO:0048478 replication fork protection(GO:0048478)
0.1 1.2 GO:0006020 inositol metabolic process(GO:0006020)
0.1 0.9 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.1 0.6 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 1.1 GO:0019321 pentose metabolic process(GO:0019321)
0.1 1.7 GO:0051451 myoblast migration(GO:0051451)
0.1 0.8 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.1 0.8 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.1 0.5 GO:0009249 protein lipoylation(GO:0009249)
0.1 1.9 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.1 0.2 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1 0.5 GO:0051204 protein insertion into mitochondrial membrane(GO:0051204)
0.1 0.5 GO:0006071 glycerol metabolic process(GO:0006071)
0.1 0.3 GO:0006788 heme oxidation(GO:0006788)
0.1 1.8 GO:0090201 negative regulation of release of cytochrome c from mitochondria(GO:0090201)
0.1 3.8 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 0.1 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.1 0.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.8 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 2.2 GO:0042491 auditory receptor cell differentiation(GO:0042491)
0.0 0.2 GO:0071475 cellular hyperosmotic salinity response(GO:0071475) negative regulation of t-circle formation(GO:1904430)
0.0 0.2 GO:1903587 negative regulation of peptidyl-serine dephosphorylation(GO:1902309) regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.0 0.7 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.6 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 1.1 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 3.6 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.7 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 4.0 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.0 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.0 1.5 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.4 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.4 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 1.2 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.5 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.2 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.2 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 0.5 GO:0007608 sensory perception of smell(GO:0007608)
0.0 1.9 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.0 0.0 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.1 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.4 GO:0007398 ectoderm development(GO:0007398) positive regulation of cell cycle arrest(GO:0071158)
0.0 0.7 GO:0042775 mitochondrial ATP synthesis coupled electron transport(GO:0042775)
0.0 0.2 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.4 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.1 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.5 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.3 GO:0006103 2-oxoglutarate metabolic process(GO:0006103)
0.0 1.3 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 0.4 GO:0035019 somatic stem cell population maintenance(GO:0035019)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 10.8 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.8 3.9 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.7 4.2 GO:0031262 Ndc80 complex(GO:0031262)
0.6 1.9 GO:1990423 RZZ complex(GO:1990423)
0.4 2.6 GO:0045179 apical cortex(GO:0045179)
0.4 2.3 GO:0044305 calyx of Held(GO:0044305)
0.3 1.3 GO:0008623 CHRAC(GO:0008623)
0.3 0.9 GO:0035061 interchromatin granule(GO:0035061)
0.3 1.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.3 2.1 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.2 2.1 GO:0002177 manchette(GO:0002177)
0.2 0.9 GO:0097454 Schwann cell microvillus(GO:0097454)
0.2 1.1 GO:0032437 cuticular plate(GO:0032437)
0.2 2.8 GO:0042788 polysomal ribosome(GO:0042788)
0.2 0.5 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.2 1.2 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.2 2.1 GO:0070852 cell body fiber(GO:0070852)
0.2 0.8 GO:0031298 replication fork protection complex(GO:0031298)
0.1 0.9 GO:0005955 calcineurin complex(GO:0005955)
0.1 1.1 GO:0033269 internode region of axon(GO:0033269)
0.1 0.4 GO:0000811 GINS complex(GO:0000811)
0.1 1.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 1.7 GO:0031045 dense core granule(GO:0031045)
0.1 0.5 GO:0030891 VCB complex(GO:0030891)
0.1 0.7 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 0.5 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 0.7 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.6 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.6 GO:0034709 methylosome(GO:0034709)
0.1 0.6 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 3.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.2 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.2 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 1.5 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.7 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 3.2 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 2.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 3.1 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.3 GO:0071439 clathrin complex(GO:0071439)
0.0 0.3 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.8 GO:0014704 intercalated disc(GO:0014704)
0.0 0.1 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.0 0.6 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 1.0 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.4 GO:0005776 autophagosome(GO:0005776)
0.0 0.6 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.3 GO:0070469 respiratory chain(GO:0070469)
0.0 0.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.4 GO:0043596 nuclear replication fork(GO:0043596)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 5.9 GO:0008142 oxysterol binding(GO:0008142)
1.3 3.9 GO:0050501 hyaluronan synthase activity(GO:0050501)
1.1 11.0 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
1.0 3.1 GO:0004980 melanocortin receptor activity(GO:0004977) melanocyte-stimulating hormone receptor activity(GO:0004980)
0.9 2.7 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.8 2.3 GO:0001565 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
0.7 2.1 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.6 3.9 GO:0000150 recombinase activity(GO:0000150)
0.4 1.7 GO:0030348 syntaxin-3 binding(GO:0030348)
0.4 1.2 GO:0031403 lithium ion binding(GO:0031403)
0.4 1.1 GO:0018738 S-formylglutathione hydrolase activity(GO:0018738)
0.3 2.9 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.3 1.9 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.3 1.1 GO:0015254 glycerol channel activity(GO:0015254)
0.2 1.4 GO:0008494 translation activator activity(GO:0008494)
0.2 1.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.2 1.7 GO:0016531 copper chaperone activity(GO:0016531)
0.2 3.8 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.2 0.6 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.2 0.5 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.2 0.5 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.2 1.8 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2 0.9 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.2 7.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 0.6 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.1 0.9 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 1.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.7 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 1.2 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 0.6 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 1.0 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.5 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 0.3 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 2.8 GO:0017091 AU-rich element binding(GO:0017091)
0.1 1.7 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.3 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.5 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 1.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.5 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 0.5 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.1 0.8 GO:0048038 quinone binding(GO:0048038)
0.0 5.7 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 1.6 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 1.1 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 1.6 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.5 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 2.9 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 4.0 GO:0001047 core promoter binding(GO:0001047)
0.0 0.4 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.7 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.5 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 3.9 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 2.3 GO:0005496 steroid binding(GO:0005496)
0.0 4.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.1 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 1.1 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.8 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 1.4 GO:0019003 GDP binding(GO:0019003)
0.0 0.4 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 1.1 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 1.0 GO:0042393 histone binding(GO:0042393)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 1.3 GO:0008186 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 1.6 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.2 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 2.6 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.8 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.6 GO:0015399 primary active transmembrane transporter activity(GO:0015399) P-P-bond-hydrolysis-driven transmembrane transporter activity(GO:0015405) ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.6 GO:0009055 electron carrier activity(GO:0009055)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 18.8 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.1 2.7 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.1 3.0 PID_BMP_PATHWAY BMP receptor signaling
0.1 0.8 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.8 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.4 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.0 5.1 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.8 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 0.6 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.5 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.2 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.9 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 0.4 PID_MYC_PATHWAY C-MYC pathway
0.0 1.1 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.0 1.2 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.6 PID_ARF_3PATHWAY Arf1 pathway
0.0 0.8 PID_ATR_PATHWAY ATR signaling pathway
0.0 1.4 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 1.0 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 0.8 PID_P73PATHWAY p73 transcription factor network
0.0 1.4 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 0.3 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.6 PID_P53_REGULATION_PATHWAY p53 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 10.8 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.7 2.1 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
0.3 2.6 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.3 2.7 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.3 3.9 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.2 1.7 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.2 1.7 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 9.4 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.1 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.0 REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 3.0 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.1 1.2 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.1 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.1 1.4 REACTOME_P38MAPK_EVENTS Genes involved in p38MAPK events
0.1 7.5 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 2.8 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.1 0.6 REACTOME_INTEGRATION_OF_ENERGY_METABOLISM Genes involved in Integration of energy metabolism
0.1 0.7 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.8 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.0 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 2.5 REACTOME_AQUAPORIN_MEDIATED_TRANSPORT Genes involved in Aquaporin-mediated transport
0.0 3.1 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 3.5 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 0.5 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.7 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.0 3.1 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.9 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.4 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.0 1.7 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME_INTEGRATION_OF_PROVIRUS Genes involved in Integration of provirus
0.0 0.8 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.3 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.7 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.6 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.0 0.8 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 3.4 REACTOME_HEMOSTASIS Genes involved in Hemostasis