Motif ID: Barhl1

Z-value: 0.658


Transcription factors associated with Barhl1:

Gene SymbolEntrez IDGene Name
Barhl1 ENSMUSG00000026805.8 Barhl1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Barhl1mm10_v2_chr2_-_28916412_289164400.048.0e-01Click!


Activity profile for motif Barhl1.

activity profile for motif Barhl1


Sorted Z-values histogram for motif Barhl1

Sorted Z-values for motif Barhl1



Network of associatons between targets according to the STRING database.



First level regulatory network of Barhl1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_43869993 3.512 ENSMUST00000067469.4
Tmem74
transmembrane protein 74
chr5_-_62766153 2.593 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr16_+_10827921 2.045 ENSMUST00000181732.1
Gm26822
predicted gene, 26822
chr16_+_92292380 2.035 ENSMUST00000047383.3
Kcne2
potassium voltage-gated channel, Isk-related subfamily, gene 2
chr3_-_146770603 1.976 ENSMUST00000106138.1
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr15_-_53902472 1.903 ENSMUST00000078673.6
Samd12
sterile alpha motif domain containing 12
chr1_+_115684727 1.873 ENSMUST00000043725.7
Cntnap5a
contactin associated protein-like 5A
chr6_-_41636389 1.852 ENSMUST00000031902.5
Trpv6
transient receptor potential cation channel, subfamily V, member 6
chr3_-_146770218 1.666 ENSMUST00000106137.1
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr18_+_37355271 1.658 ENSMUST00000051163.1
Pcdhb8
protocadherin beta 8
chr6_+_72097561 1.353 ENSMUST00000069994.4
ENSMUST00000114112.1
St3gal5

ST3 beta-galactoside alpha-2,3-sialyltransferase 5

chr3_+_75557530 1.273 ENSMUST00000161776.1
ENSMUST00000029423.8
Serpini1

serine (or cysteine) peptidase inhibitor, clade I, member 1

chr15_+_55112317 1.212 ENSMUST00000096433.3
Deptor
DEP domain containing MTOR-interacting protein
chr3_+_116008220 1.191 ENSMUST00000106502.1
Extl2
exostoses (multiple)-like 2
chr16_-_32868325 1.144 ENSMUST00000089684.3
ENSMUST00000040986.8
ENSMUST00000115105.2
1700021K19Rik


RIKEN cDNA 1700021K19 gene


chrX_+_112604274 1.137 ENSMUST00000071814.6
Zfp711
zinc finger protein 711
chr11_+_102430315 1.136 ENSMUST00000049460.4
ENSMUST00000129997.1
Grn

granulin

chr5_+_149678224 1.063 ENSMUST00000100404.3
B3galtl
beta 1,3-galactosyltransferase-like
chr2_-_45110336 1.042 ENSMUST00000028229.6
ENSMUST00000152232.1
Zeb2

zinc finger E-box binding homeobox 2

chr2_+_83812567 0.981 ENSMUST00000051454.3
Fam171b
family with sequence similarity 171, member B
chr11_+_22971991 0.868 ENSMUST00000049506.5
Zrsr1
zinc finger (CCCH type), RNA binding motif and serine/arginine rich 1
chr17_+_55892184 0.814 ENSMUST00000054780.8
Zfp959
zinc finger protein 959
chr17_-_78418083 0.739 ENSMUST00000070039.7
ENSMUST00000112487.1
Fez2

fasciculation and elongation protein zeta 2 (zygin II)

chr8_+_40307458 0.713 ENSMUST00000068999.7
Micu3
mitochondrial calcium uptake family, member 3
chr7_+_45896941 0.653 ENSMUST00000069772.7
ENSMUST00000107716.1
Tmem143

transmembrane protein 143

chr10_-_41303171 0.631 ENSMUST00000043814.3
Fig4
FIG4 homolog (S. cerevisiae)
chr18_+_12972225 0.628 ENSMUST00000025290.5
Impact
imprinted and ancient
chr17_-_25115905 0.571 ENSMUST00000024987.5
ENSMUST00000115181.2
Telo2

TEL2, telomere maintenance 2, homolog (S. cerevisiae)

chr7_+_12834743 0.543 ENSMUST00000004614.8
Zfp110
zinc finger protein 110
chr13_+_63014934 0.500 ENSMUST00000091560.4
2010111I01Rik
RIKEN cDNA 2010111I01 gene
chr1_-_75278345 0.479 ENSMUST00000039534.4
Resp18
regulated endocrine-specific protein 18
chr16_+_33251415 0.437 ENSMUST00000023502.4
Snx4
sorting nexin 4
chr6_-_59426279 0.435 ENSMUST00000051065.4
Gprin3
GPRIN family member 3
chr7_+_97842917 0.434 ENSMUST00000033040.5
Pak1
p21 protein (Cdc42/Rac)-activated kinase 1
chrX_-_75578188 0.386 ENSMUST00000033545.5
Rab39b
RAB39B, member RAS oncogene family
chr16_-_91618986 0.373 ENSMUST00000143058.1
ENSMUST00000049244.8
ENSMUST00000169982.1
ENSMUST00000133731.1
Dnajc28



DnaJ (Hsp40) homolog, subfamily C, member 28



chr13_+_63015167 0.373 ENSMUST00000021911.8
2010111I01Rik
RIKEN cDNA 2010111I01 gene
chr7_+_45897429 0.357 ENSMUST00000140243.1
Tmem143
transmembrane protein 143
chr11_+_116198853 0.349 ENSMUST00000021130.6
Ten1
TEN1 telomerase capping complex subunit
chr8_-_22694061 0.348 ENSMUST00000131767.1
Ikbkb
inhibitor of kappaB kinase beta
chr5_-_62765618 0.334 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr6_+_125349699 0.331 ENSMUST00000032491.8
Tnfrsf1a
tumor necrosis factor receptor superfamily, member 1a
chr3_-_130709419 0.202 ENSMUST00000043937.7
Ostc
oligosaccharyltransferase complex subunit
chr13_-_35027077 0.169 ENSMUST00000170538.1
ENSMUST00000163280.1
Eci2

enoyl-Coenzyme A delta isomerase 2

chr14_+_25980039 0.151 ENSMUST00000173155.1
Duxbl1
double homeobox B-like 1
chr10_+_102158858 0.148 ENSMUST00000138522.1
ENSMUST00000163753.1
ENSMUST00000138016.1
Mgat4c


mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)


chr3_-_19265007 0.139 ENSMUST00000091314.4
Pde7a
phosphodiesterase 7A
chr5_-_24581879 0.112 ENSMUST00000088299.4
Gm10221
predicted gene 10221
chr18_+_56562443 0.076 ENSMUST00000130163.1
ENSMUST00000132628.1
Phax

phosphorylated adaptor for RNA export

chr10_-_5069044 0.071 ENSMUST00000095899.3
Syne1
spectrin repeat containing, nuclear envelope 1
chr3_-_19264959 0.058 ENSMUST00000121951.1
Pde7a
phosphodiesterase 7A
chr7_+_127800604 0.037 ENSMUST00000046863.5
ENSMUST00000106272.1
ENSMUST00000139068.1
Hsd3b7


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7


chr17_+_45734506 0.035 ENSMUST00000180558.1
F630040K05Rik
RIKEN cDNA F630040K05 gene
chr8_+_31089471 0.034 ENSMUST00000036631.7
ENSMUST00000170204.1
Dusp26

dual specificity phosphatase 26 (putative)

chr11_+_78826575 0.032 ENSMUST00000147875.2
ENSMUST00000141321.1
Lyrm9

LYR motif containing 9

chr13_+_24802020 0.031 ENSMUST00000155575.1
BC005537
cDNA sequence BC005537

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.3 3.6 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.3 1.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.3 1.9 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.2 0.6 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.2 1.0 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.2 1.1 GO:0035188 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1 0.4 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1 0.3 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 0.5 GO:1990009 retinal cell apoptotic process(GO:1990009)
0.1 0.4 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.1 1.2 GO:0045792 negative regulation of cell size(GO:0045792)
0.1 0.6 GO:0031642 negative regulation of myelination(GO:0031642)
0.1 0.6 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.6 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.3 GO:1901550 regulation of endothelial cell development(GO:1901550) regulation of establishment of endothelial barrier(GO:1903140)
0.0 1.4 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.4 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.9 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.1 GO:0051030 snRNA transport(GO:0051030)
0.0 3.5 GO:0016236 macroautophagy(GO:0016236)
0.0 0.1 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.0 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0031983 vesicle lumen(GO:0031983)
0.3 3.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.9 GO:0089701 U2AF(GO:0089701)
0.1 0.5 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.6 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.3 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.4 GO:0071437 invadopodium(GO:0071437)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.4 GO:0017119 Golgi transport complex(GO:0017119)
0.0 2.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.0 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.4 1.2 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.4 3.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.6 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1 0.3 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 0.3 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.1 0.4 GO:1990460 leptin receptor binding(GO:1990460)
0.1 0.5 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 1.9 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 0.9 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 2.9 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 1.4 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 1.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.0 GO:0070412 R-SMAD binding(GO:0070412)
0.0 1.9 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.6 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.0 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 1.1 GO:0005125 cytokine activity(GO:0005125)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.6 PID_IL3_PATHWAY IL3-mediated signaling events
0.1 2.9 PID_ARF6_PATHWAY Arf6 signaling events
0.0 1.9 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.0 0.4 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.0 0.3 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.3 PID_NFKAPPAB_ATYPICAL_PATHWAY Atypical NF-kappaB pathway
0.0 1.2 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 1.3 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.6 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.6 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.3 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.4 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.3 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 2.9 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases