Motif ID: Nr2f1_Nr4a1

Z-value: 1.170

Transcription factors associated with Nr2f1_Nr4a1:

Gene SymbolEntrez IDGene Name
Nr2f1 ENSMUSG00000069171.7 Nr2f1
Nr4a1 ENSMUSG00000023034.6 Nr4a1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr4a1mm10_v2_chr15_+_101266839_101266859-0.602.8e-05Click!
Nr2f1mm10_v2_chr13_-_78197815_781979300.202.2e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Nr2f1_Nr4a1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_+_57142782 10.886 ENSMUST00000139892.1
Megf10
multiple EGF-like-domains 10
chr9_-_119578981 10.093 ENSMUST00000117911.1
ENSMUST00000120420.1
Scn5a

sodium channel, voltage-gated, type V, alpha

chr4_+_154960915 9.953 ENSMUST00000049621.6
Hes5
hairy and enhancer of split 5 (Drosophila)
chr9_-_54661666 7.716 ENSMUST00000128624.1
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr1_+_166254095 7.259 ENSMUST00000111416.1
Ildr2
immunoglobulin-like domain containing receptor 2
chr6_-_76497631 5.977 ENSMUST00000097218.5
Gm9008
predicted pseudogene 9008
chr12_-_111672290 5.863 ENSMUST00000001304.7
Ckb
creatine kinase, brain
chr12_-_110978981 5.810 ENSMUST00000135131.1
ENSMUST00000043459.6
ENSMUST00000128353.1
Ankrd9


ankyrin repeat domain 9


chr1_+_191821444 5.507 ENSMUST00000027931.7
Nek2
NIMA (never in mitosis gene a)-related expressed kinase 2
chr4_-_41697040 5.331 ENSMUST00000102962.3
ENSMUST00000084701.5
Cntfr

ciliary neurotrophic factor receptor

chr10_+_4611971 5.277 ENSMUST00000105590.1
ENSMUST00000067086.7
Esr1

estrogen receptor 1 (alpha)

chr3_-_138131356 5.218 ENSMUST00000029805.8
Mttp
microsomal triglyceride transfer protein
chr5_+_111581422 5.147 ENSMUST00000064930.3
C130026L21Rik
RIKEN cDNA C130026L21 gene
chr13_+_21722057 5.101 ENSMUST00000110476.3
Hist1h2bm
histone cluster 1, H2bm
chr3_+_146500071 5.056 ENSMUST00000119130.1
Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr11_-_100822525 4.929 ENSMUST00000107358.2
Stat5b
signal transducer and activator of transcription 5B
chr13_-_48273865 4.790 ENSMUST00000180777.1
A330048O09Rik
RIKEN cDNA A330048O09 gene
chr7_-_109616548 4.568 ENSMUST00000077909.1
ENSMUST00000084738.3
St5

suppression of tumorigenicity 5

chr10_+_128194446 4.423 ENSMUST00000044776.6
Gls2
glutaminase 2 (liver, mitochondrial)
chr1_-_172206775 4.359 ENSMUST00000013842.5
ENSMUST00000111247.1
Pea15a

phosphoprotein enriched in astrocytes 15A

chr12_+_108334341 4.327 ENSMUST00000021684.4
Cyp46a1
cytochrome P450, family 46, subfamily a, polypeptide 1
chr7_-_4522427 4.241 ENSMUST00000098859.3
Tnni3
troponin I, cardiac 3
chr8_-_46294592 4.229 ENSMUST00000058636.7
Helt
helt bHLH transcription factor
chr18_-_39490649 4.063 ENSMUST00000115567.1
Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr6_-_119544282 3.871 ENSMUST00000119369.1
ENSMUST00000178696.1
Wnt5b

wingless-related MMTV integration site 5B

chr18_+_77185815 3.820 ENSMUST00000079618.4
St8sia5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr17_+_43952999 3.807 ENSMUST00000177857.1
Rcan2
regulator of calcineurin 2
chr2_-_73911323 3.597 ENSMUST00000111996.1
ENSMUST00000018914.2
Atp5g3

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)

chr1_+_12718496 3.569 ENSMUST00000088585.3
Sulf1
sulfatase 1
chr6_+_113531675 3.537 ENSMUST00000036340.5
ENSMUST00000101051.2
Fancd2

Fanconi anemia, complementation group D2

chr11_-_70656467 3.525 ENSMUST00000131642.1
Gm12319
predicted gene 12319
chrX_+_153006461 3.516 ENSMUST00000095755.3
Usp51
ubiquitin specific protease 51
chr1_-_172206684 3.443 ENSMUST00000155109.1
Pea15a
phosphoprotein enriched in astrocytes 15A
chr7_+_4119525 3.397 ENSMUST00000119661.1
ENSMUST00000129423.1
Ttyh1

tweety homolog 1 (Drosophila)

chr10_-_13324160 3.388 ENSMUST00000105545.4
Phactr2
phosphatase and actin regulator 2
chr7_+_4119556 3.381 ENSMUST00000079415.5
Ttyh1
tweety homolog 1 (Drosophila)
chr8_-_105471481 3.374 ENSMUST00000014990.6
Tppp3
tubulin polymerization-promoting protein family member 3
chrX_+_100729917 3.245 ENSMUST00000019503.7
Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr7_-_100514800 3.210 ENSMUST00000054923.7
Dnajb13
DnaJ (Hsp40) related, subfamily B, member 13
chr10_+_94198955 3.078 ENSMUST00000020209.9
ENSMUST00000179990.1
Ndufa12

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12

chr2_+_13573927 3.052 ENSMUST00000141365.1
ENSMUST00000028062.2
Vim

vimentin

chr3_+_87971129 3.049 ENSMUST00000160694.1
Nes
nestin
chr3_+_87971071 3.021 ENSMUST00000090973.5
Nes
nestin
chr10_-_78464853 2.971 ENSMUST00000105385.1
Pdxk
pyridoxal (pyridoxine, vitamin B6) kinase
chr11_-_94677404 2.951 ENSMUST00000116349.2
Xylt2
xylosyltransferase II
chr7_-_116237767 2.950 ENSMUST00000182834.1
Plekha7
pleckstrin homology domain containing, family A member 7
chr7_-_23947237 2.941 ENSMUST00000086013.2
Gm10175
predicted gene 10175
chr1_-_120120138 2.908 ENSMUST00000112648.1
ENSMUST00000128408.1
Dbi

diazepam binding inhibitor

chr10_+_80805233 2.895 ENSMUST00000036016.4
Amh
anti-Mullerian hormone
chr11_+_70657196 2.876 ENSMUST00000157027.1
ENSMUST00000072841.5
ENSMUST00000108548.1
ENSMUST00000126241.1
Eno3



enolase 3, beta muscle



chr18_+_77773956 2.868 ENSMUST00000114748.1
Atp5a1
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1
chr3_-_109027600 2.867 ENSMUST00000171143.1
Fam102b
family with sequence similarity 102, member B
chr2_-_166155624 2.854 ENSMUST00000109249.2
Sulf2
sulfatase 2
chr4_-_137785371 2.845 ENSMUST00000133473.1
Alpl
alkaline phosphatase, liver/bone/kidney
chr13_-_73328442 2.818 ENSMUST00000022097.5
Ndufs6
NADH dehydrogenase (ubiquinone) Fe-S protein 6
chr9_-_57262591 2.818 ENSMUST00000034846.5
1700017B05Rik
RIKEN cDNA 1700017B05 gene
chr7_-_4522794 2.797 ENSMUST00000140424.1
Tnni3
troponin I, cardiac 3
chrX_-_141874870 2.774 ENSMUST00000182079.1
Gm15294
predicted gene 15294
chr10_-_78464969 2.763 ENSMUST00000041616.8
Pdxk
pyridoxal (pyridoxine, vitamin B6) kinase
chr7_+_79500081 2.738 ENSMUST00000181511.2
ENSMUST00000182937.1
AI854517

expressed sequence AI854517

chr11_-_82871133 2.736 ENSMUST00000071152.7
ENSMUST00000108173.3
Rffl

ring finger and FYVE like domain containing protein

chrX_+_71556874 2.709 ENSMUST00000123100.1
Hmgb3
high mobility group box 3
chr7_+_79500018 2.662 ENSMUST00000182495.1
ENSMUST00000183043.1
AI854517

expressed sequence AI854517

chr6_-_119467210 2.652 ENSMUST00000118120.1
Wnt5b
wingless-related MMTV integration site 5B
chr3_+_32736990 2.608 ENSMUST00000127477.1
ENSMUST00000121778.1
ENSMUST00000154257.1
Ndufb5


NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5


chr18_-_41951187 2.590 ENSMUST00000070949.4
Prelid2
PRELI domain containing 2
chr4_-_132345715 2.535 ENSMUST00000084250.4
Rcc1
regulator of chromosome condensation 1
chr6_+_17307632 2.533 ENSMUST00000115453.1
Cav1
caveolin 1, caveolae protein
chr10_+_115569986 2.524 ENSMUST00000173620.1
A930009A15Rik
RIKEN cDNA A930009A15 gene
chr4_+_140961203 2.449 ENSMUST00000010007.8
Sdhb
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
chr17_-_70849644 2.408 ENSMUST00000134654.1
ENSMUST00000172229.1
ENSMUST00000127719.1
Tgif1


TGFB-induced factor homeobox 1


chr9_-_54661870 2.401 ENSMUST00000034822.5
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr6_+_91156665 2.393 ENSMUST00000041736.4
Hdac11
histone deacetylase 11
chr2_+_121295437 2.380 ENSMUST00000110639.1
Map1a
microtubule-associated protein 1 A
chr6_+_91157373 2.371 ENSMUST00000155007.1
Hdac11
histone deacetylase 11
chr7_-_127345314 2.370 ENSMUST00000060783.5
Zfp768
zinc finger protein 768
chr1_-_175692624 2.336 ENSMUST00000027809.7
Opn3
opsin 3
chr3_+_146499850 2.326 ENSMUST00000118280.1
Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr15_+_76343504 2.307 ENSMUST00000023210.6
Cyc1
cytochrome c-1
chr5_-_116422858 2.301 ENSMUST00000036991.4
Hspb8
heat shock protein 8
chr2_-_129699833 2.289 ENSMUST00000028883.5
Pdyn
prodynorphin
chr15_-_43170809 2.280 ENSMUST00000063492.6
Rspo2
R-spondin 2 homolog (Xenopus laevis)
chr2_+_131186942 2.278 ENSMUST00000028804.8
ENSMUST00000079857.8
Cdc25b

cell division cycle 25B

chr5_+_33658123 2.245 ENSMUST00000074849.6
ENSMUST00000079534.4
Tacc3

transforming, acidic coiled-coil containing protein 3

chr10_-_13324250 2.228 ENSMUST00000105543.1
Phactr2
phosphatase and actin regulator 2
chr4_+_128993224 2.211 ENSMUST00000030583.6
ENSMUST00000102604.4
Ak2

adenylate kinase 2

chr2_+_59160838 2.196 ENSMUST00000102754.4
ENSMUST00000168631.1
ENSMUST00000123908.1
Pkp4


plakophilin 4


chr3_-_57575760 2.191 ENSMUST00000029380.7
Wwtr1
WW domain containing transcription regulator 1
chr9_-_100571049 2.186 ENSMUST00000093792.2
Slc35g2
solute carrier family 35, member G2
chr14_+_25694170 2.186 ENSMUST00000022419.6
Ppif
peptidylprolyl isomerase F (cyclophilin F)
chr15_-_35938186 2.184 ENSMUST00000014457.8
Cox6c
cytochrome c oxidase subunit VIc
chr11_-_4704334 2.174 ENSMUST00000058407.5
Uqcr10
ubiquinol-cytochrome c reductase, complex III subunit X
chr2_+_126556128 2.168 ENSMUST00000141482.2
Slc27a2
solute carrier family 27 (fatty acid transporter), member 2
chr6_-_125166463 2.167 ENSMUST00000117757.2
ENSMUST00000073605.8
Gapdh

glyceraldehyde-3-phosphate dehydrogenase

chr4_-_45108038 2.164 ENSMUST00000107809.2
ENSMUST00000107808.2
ENSMUST00000107807.1
ENSMUST00000107810.2
Tomm5



translocase of outer mitochondrial membrane 5 homolog (yeast)



chr10_-_80855187 2.161 ENSMUST00000035775.8
Lsm7
LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr12_-_111966954 2.153 ENSMUST00000021719.5
2010107E04Rik
RIKEN cDNA 2010107E04 gene
chr19_+_41911851 2.142 ENSMUST00000011896.6
Pgam1
phosphoglycerate mutase 1
chr2_+_105675429 2.113 ENSMUST00000111085.1
Pax6
paired box gene 6
chr6_+_91156772 2.106 ENSMUST00000143621.1
Hdac11
histone deacetylase 11
chr9_-_96437434 2.105 ENSMUST00000070500.2
BC043934
cDNA sequence BC043934
chr6_+_30568367 2.097 ENSMUST00000049251.5
Cpa4
carboxypeptidase A4
chr7_-_81706905 2.096 ENSMUST00000026922.7
Homer2
homer homolog 2 (Drosophila)
chr2_+_105675478 2.095 ENSMUST00000167211.2
ENSMUST00000111083.3
Pax6

paired box gene 6

chrX_+_56447965 2.084 ENSMUST00000079663.6
Gm2174
predicted gene 2174
chr2_-_131160006 2.071 ENSMUST00000103188.3
ENSMUST00000133602.1
ENSMUST00000028800.5
1700037H04Rik


RIKEN cDNA 1700037H04 gene


chr9_-_22002599 2.068 ENSMUST00000115336.2
ENSMUST00000044926.5
Ccdc151

coiled-coil domain containing 151

chr9_-_32344237 2.006 ENSMUST00000034533.5
Kcnj5
potassium inwardly-rectifying channel, subfamily J, member 5
chr1_+_137966529 2.001 ENSMUST00000182158.1
A430106G13Rik
RIKEN cDNA A430106G13 gene
chr4_-_132345686 1.998 ENSMUST00000030726.6
Rcc1
regulator of chromosome condensation 1
chr5_-_121527186 1.991 ENSMUST00000152270.1
Mapkapk5
MAP kinase-activated protein kinase 5
chr6_-_138422898 1.970 ENSMUST00000161450.1
ENSMUST00000163024.1
ENSMUST00000162185.1
Lmo3


LIM domain only 3


chr15_-_35938009 1.969 ENSMUST00000156915.1
Cox6c
cytochrome c oxidase subunit VIc
chr15_-_44428303 1.966 ENSMUST00000038719.6
Nudcd1
NudC domain containing 1
chr4_+_99955715 1.944 ENSMUST00000102783.4
Pgm2
phosphoglucomutase 2
chr14_-_13961202 1.933 ENSMUST00000065865.8
Thoc7
THO complex 7 homolog (Drosophila)
chr9_-_107668967 1.931 ENSMUST00000177567.1
Slc38a3
solute carrier family 38, member 3
chr5_+_129725063 1.927 ENSMUST00000086046.3
Gbas
glioblastoma amplified sequence
chr11_-_53430779 1.912 ENSMUST00000061326.4
ENSMUST00000109021.3
Uqcrq

ubiquinol-cytochrome c reductase, complex III subunit VII

chr17_+_29360923 1.903 ENSMUST00000024810.6
Fgd2
FYVE, RhoGEF and PH domain containing 2
chr3_-_32737147 1.881 ENSMUST00000043966.7
Mrpl47
mitochondrial ribosomal protein L47
chr8_+_108714644 1.877 ENSMUST00000043896.8
Zfhx3
zinc finger homeobox 3
chr15_+_25773985 1.876 ENSMUST00000125667.1
Myo10
myosin X
chr2_+_118598209 1.862 ENSMUST00000038341.7
Bub1b
budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)
chr6_+_83349446 1.861 ENSMUST00000136501.1
Bola3
bolA-like 3 (E. coli)
chr16_+_44139821 1.842 ENSMUST00000159514.1
ENSMUST00000161326.1
ENSMUST00000063520.8
ENSMUST00000063542.7
Naa50



N(alpha)-acetyltransferase 50, NatE catalytic subunit



chr2_-_104742802 1.839 ENSMUST00000028595.7
Depdc7
DEP domain containing 7
chr11_-_109472611 1.825 ENSMUST00000168740.1
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr5_+_34336928 1.803 ENSMUST00000182047.1
Rnf4
ring finger protein 4
chr10_-_99759658 1.788 ENSMUST00000056085.4
Csl
citrate synthase like
chr19_-_6980420 1.785 ENSMUST00000070878.8
ENSMUST00000177752.1
Fkbp2

FK506 binding protein 2

chr1_-_152386675 1.774 ENSMUST00000015124.8
Tsen15
tRNA splicing endonuclease 15 homolog (S. cerevisiae)
chr17_-_62606679 1.763 ENSMUST00000163332.1
Efna5
ephrin A5
chr11_-_114795888 1.763 ENSMUST00000000206.3
Btbd17
BTB (POZ) domain containing 17
chr1_-_172297989 1.758 ENSMUST00000085913.4
ENSMUST00000097464.2
ENSMUST00000137679.1
Atp1a2


ATPase, Na+/K+ transporting, alpha 2 polypeptide


chr2_-_157007039 1.756 ENSMUST00000103129.2
ENSMUST00000103130.1
Dsn1

DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)

chr17_+_47737030 1.756 ENSMUST00000086932.3
Tfeb
transcription factor EB
chr11_+_70657687 1.722 ENSMUST00000134087.1
ENSMUST00000170716.1
Eno3

enolase 3, beta muscle

chr2_-_157007015 1.716 ENSMUST00000146413.1
Dsn1
DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)
chr11_+_9118070 1.704 ENSMUST00000020677.1
ENSMUST00000101525.2
ENSMUST00000170444.1
Upp1


uridine phosphorylase 1


chr1_+_36691487 1.703 ENSMUST00000081180.4
Cox5b
cytochrome c oxidase subunit Vb
chr13_+_94875600 1.702 ENSMUST00000022195.10
Otp
orthopedia homolog (Drosophila)
chr3_-_51408925 1.695 ENSMUST00000038108.6
Ndufc1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1
chr10_+_93831555 1.685 ENSMUST00000095333.4
Usp44
ubiquitin specific peptidase 44
chr13_-_74350206 1.677 ENSMUST00000022062.7
Sdha
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr19_-_6996025 1.671 ENSMUST00000041686.3
ENSMUST00000180765.1
Nudt22

nudix (nucleoside diphosphate linked moiety X)-type motif 22

chr2_+_14873656 1.666 ENSMUST00000114718.1
ENSMUST00000114719.1
Cacnb2

calcium channel, voltage-dependent, beta 2 subunit

chr7_+_4925802 1.646 ENSMUST00000057612.7
Ssc5d
scavenger receptor cysteine rich domain containing (5 domains)
chr1_-_152386589 1.645 ENSMUST00000162371.1
Tsen15
tRNA splicing endonuclease 15 homolog (S. cerevisiae)
chr4_-_129542710 1.645 ENSMUST00000102597.4
Hdac1
histone deacetylase 1
chr3_+_98013503 1.636 ENSMUST00000079812.6
Notch2
notch 2
chr6_+_83137089 1.620 ENSMUST00000121093.1
ENSMUST00000087938.4
Rtkn

rhotekin

chr9_-_106158109 1.608 ENSMUST00000159809.1
ENSMUST00000162562.1
ENSMUST00000036382.6
ENSMUST00000112543.2
Glyctk



glycerate kinase



chr1_-_131097535 1.601 ENSMUST00000016672.4
Mapkapk2
MAP kinase-activated protein kinase 2
chr12_+_79029150 1.594 ENSMUST00000039928.5
Plekhh1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr5_-_5694559 1.574 ENSMUST00000115426.2
Steap2
six transmembrane epithelial antigen of prostate 2
chr9_+_106453838 1.568 ENSMUST00000024260.6
Pcbp4
poly(rC) binding protein 4
chr5_-_106458440 1.564 ENSMUST00000086795.6
Barhl2
BarH-like 2 (Drosophila)
chr5_+_64970069 1.543 ENSMUST00000031080.8
Fam114a1
family with sequence similarity 114, member A1
chr10_+_99108135 1.542 ENSMUST00000161240.2
Galnt4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4
chr3_+_68869563 1.530 ENSMUST00000054551.2
1110032F04Rik
RIKEN cDNA 1110032F04 gene
chr13_-_102958084 1.529 ENSMUST00000099202.3
ENSMUST00000172264.1
Mast4

microtubule associated serine/threonine kinase family member 4

chr5_-_24445166 1.515 ENSMUST00000115043.1
ENSMUST00000115041.1
Fastk

Fas-activated serine/threonine kinase

chr6_-_125165576 1.515 ENSMUST00000183272.1
ENSMUST00000182052.1
ENSMUST00000182277.1
Gapdh


glyceraldehyde-3-phosphate dehydrogenase


chr2_-_13011747 1.507 ENSMUST00000061545.5
C1ql3
C1q-like 3
chr5_+_137630116 1.494 ENSMUST00000175968.1
Lrch4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr6_-_67037399 1.484 ENSMUST00000043098.6
Gadd45a
growth arrest and DNA-damage-inducible 45 alpha
chr12_-_84194007 1.479 ENSMUST00000110294.1
Elmsan1
ELM2 and Myb/SANT-like domain containing 1
chr1_+_74791516 1.473 ENSMUST00000006718.8
Wnt10a
wingless related MMTV integration site 10a
chr12_+_109743787 1.464 ENSMUST00000183068.1
Mirg
miRNA containing gene
chr11_+_120484613 1.456 ENSMUST00000043627.7
Mrpl12
mitochondrial ribosomal protein L12
chr8_+_120668308 1.456 ENSMUST00000181795.1
Cox4i1
cytochrome c oxidase subunit IV isoform 1
chr10_+_128083273 1.456 ENSMUST00000026459.5
Atp5b
ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit
chr8_-_85555261 1.439 ENSMUST00000034138.5
Dnaja2
DnaJ (Hsp40) homolog, subfamily A, member 2
chr11_+_9118507 1.438 ENSMUST00000164791.1
ENSMUST00000130522.1
Upp1

uridine phosphorylase 1

chr6_+_135362931 1.412 ENSMUST00000032330.9
Emp1
epithelial membrane protein 1
chr8_+_88521344 1.402 ENSMUST00000034086.5
Nkd1
naked cuticle 1 homolog (Drosophila)
chr10_+_77864623 1.399 ENSMUST00000092366.2
Tspear
thrombospondin type laminin G domain and EAR repeats
chr5_+_136084022 1.395 ENSMUST00000100570.3
Rasa4
RAS p21 protein activator 4
chr2_+_104069819 1.388 ENSMUST00000111131.2
ENSMUST00000111132.1
ENSMUST00000129749.1
Cd59b


CD59b antigen


chr11_-_52282564 1.384 ENSMUST00000086844.3
Tcf7
transcription factor 7, T cell specific
chr16_-_91931643 1.377 ENSMUST00000023677.3
Atp5o
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
chr7_-_142578093 1.367 ENSMUST00000149974.1
ENSMUST00000152754.1
H19

H19 fetal liver mRNA

chr1_-_138842429 1.366 ENSMUST00000112026.2
ENSMUST00000019374.7
Lhx9

LIM homeobox protein 9

chr10_+_94147982 1.365 ENSMUST00000105290.2
Nr2c1
nuclear receptor subfamily 2, group C, member 1
chr2_-_180042401 1.364 ENSMUST00000029082.8
Psma7
proteasome (prosome, macropain) subunit, alpha type 7
chr13_-_34345174 1.362 ENSMUST00000040336.5
Slc22a23
solute carrier family 22, member 23
chr11_+_23020464 1.358 ENSMUST00000094363.3
ENSMUST00000151877.1
Fam161a

family with sequence similarity 161, member A

chr1_+_61638819 1.346 ENSMUST00000138768.1
ENSMUST00000075374.3
Pard3b

par-3 partitioning defective 3 homolog B (C. elegans)

chr10_+_93589413 1.330 ENSMUST00000181835.1
4933408J17Rik
RIKEN cDNA 4933408J17 gene
chr13_+_98354234 1.324 ENSMUST00000105098.3
Foxd1
forkhead box D1
chr4_-_129227883 1.308 ENSMUST00000106051.1
C77080
expressed sequence C77080
chr3_+_85915722 1.308 ENSMUST00000054148.7
Gm9790
predicted gene 9790
chr7_-_142578139 1.302 ENSMUST00000136359.1
H19
H19 fetal liver mRNA
chr12_+_85599388 1.298 ENSMUST00000050687.6
Jdp2
Jun dimerization protein 2
chr7_-_98309471 1.290 ENSMUST00000033020.7
Acer3
alkaline ceramidase 3
chr15_+_79141324 1.288 ENSMUST00000040077.6
Polr2f
polymerase (RNA) II (DNA directed) polypeptide F
chr6_+_41546730 1.283 ENSMUST00000103299.1
Trbc2
T cell receptor beta, constant 2
chr17_-_56584585 1.283 ENSMUST00000075510.5
Safb2
scaffold attachment factor B2
chr2_+_145785980 1.275 ENSMUST00000110005.1
ENSMUST00000094480.4
Rin2

Ras and Rab interactor 2


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 10.1 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
2.5 10.0 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
2.0 12.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
1.9 5.7 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
1.6 4.9 GO:0046544 regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819) development of secondary male sexual characteristics(GO:0046544)
1.6 6.4 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
1.4 5.5 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
1.3 5.3 GO:0003360 brainstem development(GO:0003360)
1.3 5.3 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
1.2 7.4 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
1.2 7.0 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
1.1 5.6 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
1.0 3.1 GO:0046133 pyrimidine ribonucleoside catabolic process(GO:0046133)
1.0 5.9 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
1.0 2.9 GO:0048162 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.9 3.7 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.9 5.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.9 2.6 GO:0030210 heparin biosynthetic process(GO:0030210)
0.9 3.5 GO:0051316 attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation(GO:0051316)
0.8 4.2 GO:0021905 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
0.8 4.1 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.8 2.4 GO:0061300 cerebellum vasculature development(GO:0061300)
0.8 2.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.8 2.3 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.7 3.7 GO:0006543 glutamine catabolic process(GO:0006543)
0.7 2.2 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.7 2.2 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.7 2.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.7 2.7 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.7 2.7 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.7 1.3 GO:0072076 nephrogenic mesenchyme development(GO:0072076)
0.6 1.9 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.6 1.9 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.6 1.8 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.6 6.5 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.6 1.8 GO:0009814 defense response, incompatible interaction(GO:0009814)
0.6 2.9 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.6 2.3 GO:0060535 trachea cartilage morphogenesis(GO:0060535)
0.6 4.4 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.6 1.7 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.5 1.6 GO:0032493 response to bacterial lipoprotein(GO:0032493)
0.5 1.6 GO:0035622 intrahepatic bile duct development(GO:0035622) cholangiocyte proliferation(GO:1990705)
0.5 2.7 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.5 2.2 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.5 2.6 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.5 1.6 GO:1902162 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162)
0.5 2.5 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.5 3.5 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.5 2.9 GO:0045218 zonula adherens maintenance(GO:0045218)
0.5 2.4 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.5 1.8 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.4 1.2 GO:0006226 dUMP biosynthetic process(GO:0006226)
0.4 1.6 GO:0061198 fungiform papilla formation(GO:0061198)
0.4 1.2 GO:0035672 regulation of cellular pH reduction(GO:0032847) oligopeptide transmembrane transport(GO:0035672)
0.4 9.7 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.4 2.8 GO:0090234 cellular response to testosterone stimulus(GO:0071394) regulation of kinetochore assembly(GO:0090234)
0.4 3.2 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.4 2.4 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.4 2.3 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.4 1.9 GO:0015817 glutamine transport(GO:0006868) histidine transport(GO:0015817) cellular response to potassium ion starvation(GO:0051365)
0.4 1.2 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.4 1.1 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
0.3 1.0 GO:0090274 positive regulation of pancreatic juice secretion(GO:0090187) positive regulation of somatostatin secretion(GO:0090274)
0.3 1.4 GO:0035262 gonad morphogenesis(GO:0035262)
0.3 2.3 GO:0007144 female meiosis I(GO:0007144)
0.3 1.0 GO:0046110 xanthine metabolic process(GO:0046110)
0.3 0.9 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.3 2.2 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.3 1.9 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.3 7.8 GO:0046325 negative regulation of glucose import(GO:0046325)
0.3 0.9 GO:0003104 positive regulation of glomerular filtration(GO:0003104) negative regulation of protein import into nucleus, translocation(GO:0033159) regulation of oligodendrocyte apoptotic process(GO:1900141) negative regulation of oligodendrocyte apoptotic process(GO:1900142) positive regulation of dendritic cell chemotaxis(GO:2000510)
0.3 0.9 GO:0001193 maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193)
0.3 2.4 GO:0006105 succinate metabolic process(GO:0006105)
0.3 1.2 GO:0015889 cobalamin transport(GO:0015889)
0.3 0.9 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.3 0.9 GO:0006106 fumarate metabolic process(GO:0006106)
0.3 0.9 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.3 0.9 GO:0021546 rhombomere development(GO:0021546)
0.3 1.1 GO:0018343 protein farnesylation(GO:0018343)
0.3 2.0 GO:0090400 stress-induced premature senescence(GO:0090400)
0.3 2.3 GO:0019388 galactose catabolic process(GO:0019388)
0.3 1.4 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.3 1.1 GO:0006014 D-ribose metabolic process(GO:0006014)
0.3 1.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.3 1.4 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.3 3.9 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.3 2.7 GO:0090527 actin filament reorganization(GO:0090527)
0.3 1.6 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535) macropinocytosis(GO:0044351)
0.3 1.6 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
0.2 0.5 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.2 4.2 GO:0001967 suckling behavior(GO:0001967)
0.2 2.2 GO:0046060 dATP metabolic process(GO:0046060)
0.2 6.7 GO:0042775 mitochondrial ATP synthesis coupled electron transport(GO:0042775)
0.2 8.5 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.2 0.9 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.2 1.1 GO:2000157 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.2 0.7 GO:0019043 establishment of viral latency(GO:0019043)
0.2 0.9 GO:0006982 response to lipid hydroperoxide(GO:0006982) cellular response to lipid hydroperoxide(GO:0071449)
0.2 1.8 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.2 0.7 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.2 0.2 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830)
0.2 1.5 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.2 2.9 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2 0.8 GO:0007113 endomitotic cell cycle(GO:0007113)
0.2 7.8 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.2 0.6 GO:0098886 modification of dendritic spine(GO:0098886)
0.2 3.3 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.2 0.6 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.2 2.1 GO:0036158 outer dynein arm assembly(GO:0036158)
0.2 0.6 GO:1990859 cellular response to endothelin(GO:1990859)
0.2 0.9 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.2 0.6 GO:0015938 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034)
0.2 0.5 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.2 1.9 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.2 1.4 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.2 2.1 GO:0035584 calcium-mediated signaling using intracellular calcium source(GO:0035584)
0.2 0.9 GO:1903527 regulation of membrane tubulation(GO:1903525) positive regulation of membrane tubulation(GO:1903527)
0.2 11.5 GO:0051384 response to glucocorticoid(GO:0051384)
0.2 0.7 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.2 1.2 GO:1903689 regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.2 4.7 GO:0016578 histone deubiquitination(GO:0016578)
0.2 3.2 GO:0006910 phagocytosis, recognition(GO:0006910)
0.2 1.2 GO:1903299 regulation of glucokinase activity(GO:0033131) regulation of hexokinase activity(GO:1903299)
0.2 1.0 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.2 0.3 GO:0019530 taurine metabolic process(GO:0019530)
0.2 0.7 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.2 1.1 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.2 0.7 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.2 2.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.2 0.3 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.2 1.2 GO:0033572 transferrin transport(GO:0033572)
0.2 0.6 GO:0015786 UDP-glucose transport(GO:0015786)
0.2 6.9 GO:0014003 oligodendrocyte development(GO:0014003)
0.2 1.1 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.2 7.9 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.2 1.7 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.2 1.4 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.4 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826)
0.1 1.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 1.3 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 2.2 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 0.3 GO:0061344 regulation of cell adhesion involved in heart morphogenesis(GO:0061344) positive regulation of ephrin receptor signaling pathway(GO:1901189)
0.1 0.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.4 GO:0030300 regulation of intestinal cholesterol absorption(GO:0030300)
0.1 0.1 GO:0046135 pyrimidine nucleoside catabolic process(GO:0046135)
0.1 0.1 GO:0034140 negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
0.1 1.3 GO:0046512 sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.1 0.7 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.1 1.0 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.2 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.1 1.8 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 0.4 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.1 0.8 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 1.5 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 0.6 GO:1903755 regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
0.1 0.5 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.1 0.6 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 0.8 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1 0.9 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.1 0.5 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 1.6 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 1.0 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 1.0 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.1 0.4 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.1 0.8 GO:0097066 response to thyroid hormone(GO:0097066)
0.1 3.9 GO:0035082 axoneme assembly(GO:0035082)
0.1 0.5 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 0.5 GO:0060056 mammary gland involution(GO:0060056)
0.1 0.4 GO:0000189 MAPK import into nucleus(GO:0000189)
0.1 0.6 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.3 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 1.7 GO:0002052 positive regulation of neuroblast proliferation(GO:0002052)
0.1 0.9 GO:0060539 diaphragm development(GO:0060539)
0.1 1.1 GO:0015732 prostaglandin transport(GO:0015732)
0.1 0.2 GO:0046078 dUMP metabolic process(GO:0046078)
0.1 1.2 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 4.0 GO:0051290 protein heterotetramerization(GO:0051290)
0.1 0.6 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.2 GO:0035811 negative regulation of urine volume(GO:0035811)
0.1 0.7 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.1 0.6 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.1 0.4 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 1.4 GO:0032060 bleb assembly(GO:0032060)
0.1 0.4 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 0.6 GO:0060347 heart trabecula formation(GO:0060347)
0.1 0.2 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1 1.0 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.3 GO:0019695 choline metabolic process(GO:0019695)
0.1 1.3 GO:0045116 protein neddylation(GO:0045116)
0.1 0.3 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.1 5.3 GO:0046847 filopodium assembly(GO:0046847)
0.1 0.9 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.3 GO:0045346 regulation of MHC class II biosynthetic process(GO:0045346) negative regulation of MHC class II biosynthetic process(GO:0045347)
0.1 1.6 GO:0001709 cell fate determination(GO:0001709)
0.1 1.5 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.1 1.7 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 1.3 GO:0031065 positive regulation of histone deacetylation(GO:0031065)
0.1 0.6 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.1 0.5 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.1 0.4 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 0.4 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 0.4 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.7 GO:0061436 establishment of skin barrier(GO:0061436)
0.1 0.2 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.1 0.9 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.1 0.5 GO:0046459 short-chain fatty acid metabolic process(GO:0046459)
0.1 0.6 GO:0071318 cellular response to ATP(GO:0071318)
0.1 0.2 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.1 5.1 GO:0006334 nucleosome assembly(GO:0006334)
0.1 3.0 GO:0032543 mitochondrial translation(GO:0032543)
0.1 1.7 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.0 0.1 GO:0002741 positive regulation of cytokine secretion involved in immune response(GO:0002741)
0.0 0.5 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.3 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 1.1 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.5 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.4 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.4 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.0 0.1 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0 1.4 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.4 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.7 GO:0090344 negative regulation of cell aging(GO:0090344)
0.0 1.4 GO:0042026 protein refolding(GO:0042026)
0.0 2.3 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.4 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.8 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.6 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.1 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.2 GO:0010694 positive regulation of alkaline phosphatase activity(GO:0010694)
0.0 0.7 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.5 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.7 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 0.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.8 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.5 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 0.1 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 1.0 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.2 GO:0043649 dicarboxylic acid catabolic process(GO:0043649)
0.0 0.4 GO:0061470 interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619)
0.0 1.0 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 4.1 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.0 0.5 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.3 GO:0048144 fibroblast proliferation(GO:0048144)
0.0 0.3 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.6 GO:0030218 erythrocyte differentiation(GO:0030218)
0.0 1.9 GO:0046785 microtubule polymerization(GO:0046785)
0.0 0.2 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 1.0 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 2.6 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.1 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.0 1.1 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.8 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.2 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.4 GO:0048643 positive regulation of skeletal muscle tissue development(GO:0048643)
0.0 0.3 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.0 0.9 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.1 GO:0006706 steroid catabolic process(GO:0006706)
0.0 0.9 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.1 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 1.0 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.8 GO:0030317 sperm motility(GO:0030317)
0.0 0.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) glycosylceramide biosynthetic process(GO:0046476)
0.0 0.6 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.9 GO:0051145 smooth muscle cell differentiation(GO:0051145)
0.0 0.2 GO:0050892 intestinal absorption(GO:0050892)
0.0 1.9 GO:0051028 mRNA transport(GO:0051028)
0.0 1.3 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.5 GO:0006414 translational elongation(GO:0006414)
0.0 0.1 GO:0010155 regulation of proton transport(GO:0010155)
0.0 0.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.5 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.4 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.5 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 0.4 GO:0048255 mRNA stabilization(GO:0048255)
0.0 0.4 GO:1901998 toxin transport(GO:1901998)
0.0 0.1 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.6 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.2 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.9 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 0.9 GO:2000278 regulation of DNA biosynthetic process(GO:2000278)
0.0 0.6 GO:0006096 glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757)
0.0 0.5 GO:0061515 myeloid cell development(GO:0061515)
0.0 0.3 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 3.4 GO:0097427 microtubule bundle(GO:0097427)
2.5 7.4 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
2.3 6.8 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
1.8 5.3 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
1.8 7.0 GO:1990584 cardiac Troponin complex(GO:1990584)
1.3 5.1 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.9 8.9 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.9 3.5 GO:0000939 nuclear MIS12/MIND complex(GO:0000818) condensed chromosome inner kinetochore(GO:0000939)
0.8 3.1 GO:0045098 type III intermediate filament(GO:0045098)
0.8 5.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.7 5.5 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.6 9.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.5 3.7 GO:0097452 GAIT complex(GO:0097452)
0.5 5.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.4 2.2 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.4 2.1 GO:0032426 stereocilium tip(GO:0032426)
0.4 6.6 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.4 3.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.4 1.2 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.4 1.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.3 2.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.3 14.7 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.3 2.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.3 5.1 GO:0031528 microvillus membrane(GO:0031528)
0.3 3.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.3 1.1 GO:0070069 cytochrome complex(GO:0070069)
0.3 7.0 GO:0001891 phagocytic cup(GO:0001891)
0.3 2.5 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.3 3.5 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.3 2.9 GO:0005915 zonula adherens(GO:0005915)
0.2 1.2 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.2 1.2 GO:0034715 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
0.2 1.8 GO:0031415 NatA complex(GO:0031415)
0.2 4.6 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.2 2.7 GO:0005844 polysome(GO:0005844)
0.2 0.6 GO:0071001 U4/U6 snRNP(GO:0071001)
0.2 1.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.2 1.9 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.2 1.9 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2 2.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2 0.7 GO:0032021 NELF complex(GO:0032021)
0.2 2.2 GO:0030057 desmosome(GO:0030057)
0.2 2.8 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.2 1.7 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 1.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 1.4 GO:0046930 pore complex(GO:0046930)
0.1 1.4 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 10.3 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.1 1.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 2.2 GO:0032156 septin cytoskeleton(GO:0032156)
0.1 1.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.9 GO:0032009 early phagosome(GO:0032009)
0.1 0.7 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 0.6 GO:0097444 spine apparatus(GO:0097444)
0.1 1.0 GO:0002177 manchette(GO:0002177)
0.1 0.6 GO:1990356 sumoylated E2 ligase complex(GO:1990356)
0.1 0.6 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 2.3 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 2.9 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.9 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.1 1.0 GO:0071439 clathrin complex(GO:0071439)
0.1 10.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 0.5 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 0.3 GO:0036125 mitochondrial fatty acid beta-oxidation multienzyme complex(GO:0016507) fatty acid beta-oxidation multienzyme complex(GO:0036125)
0.1 2.2 GO:0005581 collagen trimer(GO:0005581)
0.1 0.6 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.6 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 5.0 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 0.5 GO:0000125 PCAF complex(GO:0000125)
0.1 0.9 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 0.7 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 0.5 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 5.9 GO:0000786 nucleosome(GO:0000786)
0.1 0.2 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.1 1.0 GO:1990635 proximal dendrite(GO:1990635)
0.1 3.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 1.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.1 GO:0010009 cytoplasmic side of endosome membrane(GO:0010009)
0.1 0.3 GO:0031983 vesicle lumen(GO:0031983)
0.1 3.7 GO:0005882 intermediate filament(GO:0005882)
0.1 0.4 GO:0000124 SAGA complex(GO:0000124)
0.1 4.1 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 12.8 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 0.5 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 1.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.3 GO:0097443 sorting endosome(GO:0097443)
0.1 0.4 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 3.5 GO:0000793 condensed chromosome(GO:0000793)
0.1 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.9 GO:1904115 axon cytoplasm(GO:1904115)
0.1 0.5 GO:0045298 tubulin complex(GO:0045298)
0.1 0.9 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.1 1.1 GO:0035253 ciliary rootlet(GO:0035253)
0.1 3.7 GO:0016605 PML body(GO:0016605)
0.0 0.2 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 1.8 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.2 GO:0031523 Myb complex(GO:0031523)
0.0 0.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 1.5 GO:0002102 podosome(GO:0002102)
0.0 1.2 GO:0016592 mediator complex(GO:0016592)
0.0 0.7 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.8 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.7 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.3 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 14.3 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.6 GO:0098800 inner mitochondrial membrane protein complex(GO:0098800)
0.0 0.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0032280 symmetric synapse(GO:0032280)
0.0 1.9 GO:0016459 myosin complex(GO:0016459)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 1.2 GO:0009925 basal plasma membrane(GO:0009925)
0.0 3.3 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.3 GO:0010369 chromocenter(GO:0010369)
0.0 0.8 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 8.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 2.1 GO:0015934 large ribosomal subunit(GO:0015934)
0.0 0.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 1.3 GO:0031526 brush border membrane(GO:0031526)
0.0 0.6 GO:0015030 Cajal body(GO:0015030)
0.0 6.3 GO:0016607 nuclear speck(GO:0016607)
0.0 2.4 GO:0005884 actin filament(GO:0005884)
0.0 0.9 GO:0010008 endosome membrane(GO:0010008)
0.0 2.2 GO:0000922 spindle pole(GO:0000922)
0.0 1.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 1.2 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.7 GO:0030118 clathrin coat(GO:0030118)
0.0 0.6 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 3.2 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.1 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.3 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.6 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.4 GO:0030315 T-tubule(GO:0030315)
0.0 0.9 GO:0005814 centriole(GO:0005814)
0.0 0.2 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 2.3 GO:0016604 nuclear body(GO:0016604)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 7.0 GO:0030172 troponin C binding(GO:0030172)
1.9 5.7 GO:0031403 lithium ion binding(GO:0031403)
1.8 5.3 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
1.7 5.1 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
1.7 6.8 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
1.6 10.9 GO:0001849 complement component C1q binding(GO:0001849)
1.3 9.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
1.3 6.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
1.2 3.7 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
1.2 12.7 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
1.0 4.1 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
1.0 3.0 GO:0030158 protein xylosyltransferase activity(GO:0030158)
1.0 2.9 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.9 2.6 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.9 4.3 GO:0043532 angiostatin binding(GO:0043532)
0.9 2.6 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.8 4.7 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.8 2.3 GO:0009881 photoreceptor activity(GO:0009881)
0.8 3.1 GO:1990254 keratin filament binding(GO:1990254)
0.8 4.5 GO:0043199 Ran guanyl-nucleotide exchange factor activity(GO:0005087) sulfate binding(GO:0043199)
0.7 3.7 GO:0004359 glutaminase activity(GO:0004359)
0.7 5.8 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.7 2.1 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.7 2.8 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.7 6.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.7 2.7 GO:0004111 creatine kinase activity(GO:0004111)
0.6 1.9 GO:0015182 L-asparagine transmembrane transporter activity(GO:0015182)
0.6 3.8 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.6 2.3 GO:0036468 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
0.6 3.4 GO:0000213 tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.5 2.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.5 2.5 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.5 10.7 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.5 2.8 GO:0033142 progesterone receptor binding(GO:0033142)
0.5 6.8 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.4 1.8 GO:1990239 steroid hormone binding(GO:1990239)
0.4 3.5 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.4 1.2 GO:0004998 transferrin receptor activity(GO:0004998)
0.4 1.6 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.4 2.0 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.4 3.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.4 2.7 GO:0016018 cyclosporin A binding(GO:0016018)
0.4 1.2 GO:0016015 morphogen activity(GO:0016015)
0.4 1.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.3 4.1 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.3 6.9 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.3 1.7 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.3 2.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.3 0.9 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.3 0.9 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.3 1.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.3 1.2 GO:0004064 arylesterase activity(GO:0004064)
0.3 1.5 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.3 0.9 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.3 2.0 GO:0001515 opioid peptide activity(GO:0001515)
0.3 0.6 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.3 1.1 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.3 4.2 GO:0003680 AT DNA binding(GO:0003680)
0.3 0.8 GO:0004658 propionyl-CoA carboxylase activity(GO:0004658)
0.2 2.9 GO:0070097 delta-catenin binding(GO:0070097)
0.2 0.7 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.2 1.0 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.2 1.0 GO:0043546 molybdenum ion binding(GO:0030151) molybdopterin cofactor binding(GO:0043546)
0.2 2.4 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2 0.7 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.2 8.9 GO:0005109 frizzled binding(GO:0005109)
0.2 1.3 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.2 1.3 GO:0017040 ceramidase activity(GO:0017040)
0.2 0.6 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.2 0.6 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.2 1.0 GO:0004594 pantothenate kinase activity(GO:0004594)
0.2 1.6 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.2 1.7 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.2 1.8 GO:0015266 protein channel activity(GO:0015266)
0.2 5.1 GO:0009055 electron carrier activity(GO:0009055)
0.2 1.3 GO:0048018 receptor agonist activity(GO:0048018)
0.2 4.2 GO:0034185 apolipoprotein binding(GO:0034185)
0.2 5.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.2 1.0 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.2 1.2 GO:0031419 cobalamin binding(GO:0031419)
0.2 1.2 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.2 1.3 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.2 0.8 GO:0070404 NADH binding(GO:0070404)
0.2 1.1 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.1 1.8 GO:0005167 neurotrophin TRK receptor binding(GO:0005167)
0.1 2.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 1.8 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.7 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.9 GO:0015197 peptide transporter activity(GO:0015197)
0.1 0.4 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 1.3 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 1.5 GO:0008301 DNA binding, bending(GO:0008301)
0.1 1.0 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 3.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 0.9 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 0.6 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 1.8 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 1.2 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 0.4 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.1 1.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 2.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.6 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.1 1.0 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 0.5 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 7.0 GO:0005080 protein kinase C binding(GO:0005080)
0.1 1.8 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 19.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 0.6 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.4 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.1 0.3 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 1.4 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.1 1.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.5 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 0.6 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 1.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.8 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.5 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 0.7 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.1 1.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.6 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.9 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.9 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 1.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.4 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.6 GO:0008227 G-protein coupled amine receptor activity(GO:0008227)
0.1 1.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 6.5 GO:0051082 unfolded protein binding(GO:0051082)
0.1 3.1 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.1 0.4 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 3.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.6 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.1 1.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.6 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 0.9 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 0.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.8 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.1 0.6 GO:0001848 complement binding(GO:0001848)
0.1 4.2 GO:0002039 p53 binding(GO:0002039)
0.1 0.6 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 1.6 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 1.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 3.6 GO:0005518 collagen binding(GO:0005518)
0.1 0.8 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 2.5 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 0.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.4 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 1.2 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.1 0.4 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 0.2 GO:0036470 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.1 0.2 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.0 0.0 GO:0032052 bile acid binding(GO:0032052)
0.0 0.9 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.1 GO:0002054 nucleobase binding(GO:0002054)
0.0 0.4 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.0 0.9 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.0 0.5 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.9 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 1.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.1 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.8 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 2.3 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 1.2 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.7 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 1.1 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 1.5 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.5 GO:0001067 regulatory region nucleic acid binding(GO:0001067)
0.0 2.0 GO:0072341 modified amino acid binding(GO:0072341)
0.0 1.2 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.4 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.5 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 4.2 GO:0001047 core promoter binding(GO:0001047)
0.0 1.9 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.0 0.7 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.6 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.3 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.5 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0 2.3 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.2 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 4.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.4 GO:0030332 cyclin binding(GO:0030332)
0.0 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 2.1 GO:0008201 heparin binding(GO:0008201)
0.0 1.3 GO:0019003 GDP binding(GO:0019003)
0.0 0.5 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.8 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.6 GO:0005507 copper ion binding(GO:0005507)
0.0 0.5 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 2.4 GO:0042393 histone binding(GO:0042393)
0.0 0.4 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 0.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.3 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.9 GO:0008186 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 0.1 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.7 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.3 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.0 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.5 GO:0051087 chaperone binding(GO:0051087)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.9 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.3 3.5 PID_ALK2_PATHWAY ALK2 signaling events
0.3 2.3 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2 16.1 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.2 2.5 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.1 18.5 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.1 5.0 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.1 3.8 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 4.8 PID_ATR_PATHWAY ATR signaling pathway
0.1 3.3 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.1 3.7 PID_AURORA_A_PATHWAY Aurora A signaling
0.1 8.9 PID_CDC42_PATHWAY CDC42 signaling events
0.1 3.1 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.1 3.1 PID_AURORA_B_PATHWAY Aurora B signaling
0.1 2.1 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 0.6 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 6.6 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.1 1.1 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.1 2.6 PID_PLK1_PATHWAY PLK1 signaling events
0.1 3.4 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 0.9 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.1 1.9 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 1.4 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.1 1.0 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.1 1.2 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.1 1.6 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 0.6 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.7 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 3.4 PID_CMYB_PATHWAY C-MYB transcription factor network
0.0 5.6 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 5.5 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 6.9 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 2.4 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 1.5 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.6 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 1.4 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 0.8 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 2.1 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 0.8 PID_TNF_PATHWAY TNF receptor signaling pathway
0.0 0.6 PID_E2F_PATHWAY E2F transcription factor network
0.0 0.5 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.2 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.0 0.3 ST_G_ALPHA_I_PATHWAY G alpha i Pathway
0.0 0.3 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 6.6 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.5 1.6 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.5 5.8 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.5 36.1 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.4 7.5 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.4 3.4 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.4 5.2 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.4 9.5 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.4 3.5 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.4 7.7 REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.3 1.9 REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.3 3.8 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.3 9.6 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.3 19.2 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.2 10.6 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.2 2.3 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.2 7.0 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 4.9 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.2 2.9 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 1.2 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 1.9 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.1 3.8 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.4 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.1 5.1 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.1 6.6 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.1 1.1 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.1 8.4 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 2.3 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 2.2 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 3.7 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 2.0 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 4.0 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 3.1 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.1 1.7 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 1.7 REACTOME_P38MAPK_EVENTS Genes involved in p38MAPK events
0.1 1.2 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 4.6 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 1.0 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 0.7 REACTOME_ELONGATION_ARREST_AND_RECOVERY Genes involved in Elongation arrest and recovery
0.1 1.6 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 0.7 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.1 5.7 REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE Genes involved in Late Phase of HIV Life Cycle
0.1 0.8 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 0.8 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 2.3 REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.1 0.6 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 0.6 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.1 0.6 REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.1 1.2 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 0.9 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 1.5 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.6 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 7.0 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.6 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 2.5 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 3.5 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.4 REACTOME_CELL_CELL_JUNCTION_ORGANIZATION Genes involved in Cell-cell junction organization
0.0 1.4 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.7 REACTOME_CIRCADIAN_CLOCK Genes involved in Circadian Clock
0.0 0.3 REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.2 REACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM Genes involved in Bile acid and bile salt metabolism
0.0 0.4 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.3 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.0 1.6 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.5 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.0 0.8 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.2 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.6 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.6 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.6 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 2.2 REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.5 REACTOME_ENOS_ACTIVATION_AND_REGULATION Genes involved in eNOS activation and regulation
0.0 0.5 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.1 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.3 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.4 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.5 REACTOME_TRANSLATION Genes involved in Translation
0.0 0.2 REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.2 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA