Motif ID: Arnt2

Z-value: 0.264


Transcription factors associated with Arnt2:

Gene SymbolEntrez IDGene Name
Arnt2 ENSMUSG00000015709.8 Arnt2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Arnt2mm10_v2_chr7_-_84409959_844100020.453.4e-03Click!


Activity profile for motif Arnt2.

activity profile for motif Arnt2


Sorted Z-values histogram for motif Arnt2

Sorted Z-values for motif Arnt2



Network of associatons between targets according to the STRING database.



First level regulatory network of Arnt2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_137862270 0.789 ENSMUST00000130407.1
Ece1
endothelin converting enzyme 1
chr13_+_13590402 0.678 ENSMUST00000110559.1
Lyst
lysosomal trafficking regulator
chr4_+_101496648 0.655 ENSMUST00000106930.1
ENSMUST00000154120.1
Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr14_-_63543931 0.629 ENSMUST00000058679.5
Mtmr9
myotubularin related protein 9
chr1_-_58973421 0.497 ENSMUST00000173590.1
ENSMUST00000027186.5
Trak2

trafficking protein, kinesin binding 2

chr2_-_33371400 0.471 ENSMUST00000113164.1
ENSMUST00000091039.2
ENSMUST00000042615.6
Ralgps1


Ral GEF with PH domain and SH3 binding motif 1


chr1_-_52817503 0.463 ENSMUST00000162576.1
Inpp1
inositol polyphosphate-1-phosphatase
chr17_-_46890405 0.446 ENSMUST00000086675.3
A330017A19Rik
RIKEN cDNA A330017A19 gene
chr5_-_135251209 0.411 ENSMUST00000062572.2
Fzd9
frizzled homolog 9 (Drosophila)
chr11_+_107547925 0.403 ENSMUST00000100305.1
ENSMUST00000075012.1
ENSMUST00000106746.1
Helz


helicase with zinc finger domain


chr2_-_33371486 0.349 ENSMUST00000113165.1
Ralgps1
Ral GEF with PH domain and SH3 binding motif 1
chr2_-_54085542 0.334 ENSMUST00000100089.2
Rprm
reprimo, TP53 dependent G2 arrest mediator candidate
chr18_+_31634374 0.328 ENSMUST00000025109.7
Sap130
Sin3A associated protein
chr18_+_31634368 0.311 ENSMUST00000178164.1
Sap130
Sin3A associated protein
chr1_+_87327044 0.307 ENSMUST00000173173.1
Gigyf2
GRB10 interacting GYF protein 2
chr1_+_87327008 0.298 ENSMUST00000172794.1
ENSMUST00000164992.2
Gigyf2

GRB10 interacting GYF protein 2

chr6_+_4601124 0.280 ENSMUST00000181734.1
ENSMUST00000141359.1
Casd1

CAS1 domain containing 1

chr12_-_59011996 0.248 ENSMUST00000021375.5
Sec23a
SEC23A (S. cerevisiae)
chr8_+_83900706 0.236 ENSMUST00000045393.8
ENSMUST00000132500.1
ENSMUST00000152978.1
Lphn1


latrophilin 1


chr5_+_64803513 0.217 ENSMUST00000165536.1
Klf3
Kruppel-like factor 3 (basic)
chr7_-_45370559 0.216 ENSMUST00000003971.7
Lin7b
lin-7 homolog B (C. elegans)
chr1_-_52817643 0.201 ENSMUST00000027271.2
Inpp1
inositol polyphosphate-1-phosphatase
chr1_+_59912972 0.196 ENSMUST00000036540.5
Fam117b
family with sequence similarity 117, member B
chr2_+_79255500 0.171 ENSMUST00000099972.4
Itga4
integrin alpha 4
chr4_-_41275091 0.161 ENSMUST00000030143.6
ENSMUST00000108068.1
Ubap2

ubiquitin-associated protein 2

chr2_+_27886416 0.147 ENSMUST00000028280.7
Col5a1
collagen, type V, alpha 1
chr1_+_58973521 0.130 ENSMUST00000114296.1
ENSMUST00000027185.4
Stradb

STE20-related kinase adaptor beta

chr17_-_26508463 0.125 ENSMUST00000025025.6
Dusp1
dual specificity phosphatase 1
chr15_-_38078842 0.087 ENSMUST00000110336.2
Ubr5
ubiquitin protein ligase E3 component n-recognin 5
chr13_+_118714678 0.072 ENSMUST00000022246.8
Fgf10
fibroblast growth factor 10
chr7_+_130865835 0.055 ENSMUST00000075181.4
ENSMUST00000048180.5
Plekha1

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1

chr1_-_16619245 0.043 ENSMUST00000182984.1
ENSMUST00000182554.1
Ube2w

ubiquitin-conjugating enzyme E2W (putative)

chr2_+_19658055 0.037 ENSMUST00000052168.4
Otud1
OTU domain containing 1
chrX_+_99136119 0.029 ENSMUST00000052839.6
Efnb1
ephrin B1
chr4_-_48279544 0.021 ENSMUST00000030028.4
Erp44
endoplasmic reticulum protein 44
chr1_+_87326997 0.010 ENSMUST00000027475.8
Gigyf2
GRB10 interacting GYF protein 2
chr2_-_91649785 0.002 ENSMUST00000111333.1
Zfp408
zinc finger protein 408

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.2 0.7 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.2 0.8 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.1 0.4 GO:1990523 bone regeneration(GO:1990523)
0.1 0.7 GO:0072318 clathrin coat disassembly(GO:0072318)
0.1 0.5 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.2 GO:0050904 diapedesis(GO:0050904)
0.0 0.1 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.1 GO:0071336 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.0 0.6 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.0 0.7 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.6 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.6 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.4 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.5 GO:0032839 dendrite cytoplasm(GO:0032839)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.1 0.8 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.2 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.0 0.3 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.5 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID_WNT_SIGNALING_PATHWAY Wnt signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.2 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC