Motif ID: Meis1

Z-value: 0.895


Transcription factors associated with Meis1:

Gene SymbolEntrez IDGene Name
Meis1 ENSMUSG00000020160.12 Meis1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Meis1mm10_v2_chr11_-_19018714_190188280.417.4e-03Click!


Activity profile for motif Meis1.

activity profile for motif Meis1


Sorted Z-values histogram for motif Meis1

Sorted Z-values for motif Meis1



Network of associatons between targets according to the STRING database.



First level regulatory network of Meis1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_139543889 9.146 ENSMUST00000174792.1
ENSMUST00000031523.8
Uncx

UNC homeobox

chr1_-_138842429 3.244 ENSMUST00000112026.2
ENSMUST00000019374.7
Lhx9

LIM homeobox protein 9

chr11_-_64436653 3.102 ENSMUST00000177999.1
F930015N05Rik
RIKEN cDNA F930015N05 gene
chr3_+_125404292 2.570 ENSMUST00000144344.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr9_+_87022014 2.393 ENSMUST00000168529.2
ENSMUST00000174724.1
ENSMUST00000173126.1
Cyb5r4


cytochrome b5 reductase 4


chr17_-_45659312 2.338 ENSMUST00000120717.1
Capn11
calpain 11
chr11_+_44617310 2.231 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
Ebf1


early B cell factor 1


chr14_-_98169542 2.122 ENSMUST00000069334.7
ENSMUST00000071533.6
Dach1

dachshund 1 (Drosophila)

chr16_-_50732707 1.969 ENSMUST00000169791.2
5330426P16Rik
RIKEN cDNA 5330426P16 gene
chr8_+_127064107 1.925 ENSMUST00000162536.1
ENSMUST00000026921.6
ENSMUST00000162665.1
ENSMUST00000160766.1
ENSMUST00000162602.1
ENSMUST00000162531.1
ENSMUST00000160581.1
ENSMUST00000161355.1
ENSMUST00000159537.1
Pard3








par-3 (partitioning defective 3) homolog (C. elegans)








chr7_+_51621830 1.851 ENSMUST00000032710.5
Slc17a6
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
chr8_+_127064022 1.830 ENSMUST00000160272.1
ENSMUST00000079777.5
ENSMUST00000162907.1
Pard3


par-3 (partitioning defective 3) homolog (C. elegans)


chr6_+_4747306 1.724 ENSMUST00000175823.1
ENSMUST00000176204.1
ENSMUST00000166678.1
Peg10


paternally expressed 10


chr14_+_13284774 1.700 ENSMUST00000070323.5
Synpr
synaptoporin
chr3_+_109123104 1.675 ENSMUST00000029477.6
Slc25a24
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 24
chr15_+_23036449 1.593 ENSMUST00000164787.1
Cdh18
cadherin 18
chr2_-_180776900 1.488 ENSMUST00000108878.1
Bhlhe23
basic helix-loop-helix family, member e23
chr6_-_136941494 1.458 ENSMUST00000111892.1
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr7_+_70388305 1.426 ENSMUST00000080024.5
B130024G19Rik
RIKEN cDNA B130024G19 gene
chr3_+_134828993 1.404 ENSMUST00000029822.4
Tacr3
tachykinin receptor 3
chr1_-_105356658 1.346 ENSMUST00000058688.5
ENSMUST00000172299.1
Rnf152

ring finger protein 152

chr10_-_85127977 1.308 ENSMUST00000050813.2
Mterfd3
MTERF domain containing 3
chr14_-_72709534 1.260 ENSMUST00000162478.1
Fndc3a
fibronectin type III domain containing 3A
chr17_+_31296191 1.256 ENSMUST00000165149.1
Slc37a1
solute carrier family 37 (glycerol-3-phosphate transporter), member 1
chr2_-_112480817 1.245 ENSMUST00000099589.2
Chrm5
cholinergic receptor, muscarinic 5
chr1_-_169969143 1.186 ENSMUST00000027989.6
ENSMUST00000111353.3
Hsd17b7

hydroxysteroid (17-beta) dehydrogenase 7

chr17_-_23844155 1.148 ENSMUST00000122936.1
ENSMUST00000024926.7
ENSMUST00000151797.1
Prss41


protease, serine, 41


chr1_+_169969409 1.139 ENSMUST00000180638.1
3110045C21Rik
RIKEN cDNA 3110045C21 gene
chr11_-_58801944 1.128 ENSMUST00000094156.4
ENSMUST00000060581.3
Fam183b

family with sequence similarity 183, member B

chr6_-_149101506 1.103 ENSMUST00000127727.1
Dennd5b
DENN/MADD domain containing 5B
chr4_+_128755364 1.078 ENSMUST00000106077.1
A3galt2
alpha 1,3-galactosyltransferase 2 (isoglobotriaosylceramide synthase)
chr7_+_28863831 1.071 ENSMUST00000138272.1
Lgals7
lectin, galactose binding, soluble 7
chrY_+_90755657 1.063 ENSMUST00000167967.2
Gm21857
predicted gene, 21857
chr8_-_41133697 1.058 ENSMUST00000155055.1
ENSMUST00000059115.6
ENSMUST00000145860.1
Mtus1


mitochondrial tumor suppressor 1


chr10_+_69208546 1.030 ENSMUST00000164034.1
Rhobtb1
Rho-related BTB domain containing 1
chr8_+_108714644 0.984 ENSMUST00000043896.8
Zfhx3
zinc finger homeobox 3
chr3_+_55461758 0.975 ENSMUST00000070418.4
Dclk1
doublecortin-like kinase 1
chrX_+_155262443 0.964 ENSMUST00000026324.9
Acot9
acyl-CoA thioesterase 9
chr5_+_67607873 0.946 ENSMUST00000087241.5
Shisa3
shisa homolog 3 (Xenopus laevis)
chr7_+_142472080 0.929 ENSMUST00000105966.1
Lsp1
lymphocyte specific 1
chr15_+_100761741 0.877 ENSMUST00000023776.6
Slc4a8
solute carrier family 4 (anion exchanger), member 8
chr1_+_85793411 0.857 ENSMUST00000113360.1
ENSMUST00000126962.1
Cab39

calcium binding protein 39

chr3_+_116594959 0.852 ENSMUST00000029571.8
Sass6
spindle assembly 6 homolog (C. elegans)
chr6_-_149101674 0.844 ENSMUST00000111557.1
Dennd5b
DENN/MADD domain containing 5B
chr17_+_53584124 0.828 ENSMUST00000164390.1
Kat2b
K(lysine) acetyltransferase 2B
chr9_-_75409352 0.816 ENSMUST00000168937.1
Mapk6
mitogen-activated protein kinase 6
chr7_+_142471838 0.816 ENSMUST00000038946.2
Lsp1
lymphocyte specific 1
chr7_+_90426312 0.805 ENSMUST00000061391.7
Ccdc89
coiled-coil domain containing 89
chr7_+_51880312 0.796 ENSMUST00000145049.1
Gas2
growth arrest specific 2
chr2_-_121442574 0.795 ENSMUST00000116432.1
Ell3
elongation factor RNA polymerase II-like 3
chr6_-_99632376 0.786 ENSMUST00000176255.1
Gm20696
predicted gene 20696
chr7_-_143460989 0.771 ENSMUST00000167912.1
ENSMUST00000037287.6
Cdkn1c

cyclin-dependent kinase inhibitor 1C (P57)

chr15_+_61985540 0.758 ENSMUST00000159327.1
ENSMUST00000167731.1
Myc

myelocytomatosis oncogene

chr8_-_125492710 0.758 ENSMUST00000108775.1
Sipa1l2
signal-induced proliferation-associated 1 like 2
chr4_-_12087912 0.753 ENSMUST00000050686.3
Tmem67
transmembrane protein 67
chr2_-_165852149 0.751 ENSMUST00000109258.3
Zmynd8
zinc finger, MYND-type containing 8
chrX_-_23365044 0.741 ENSMUST00000115313.1
Klhl13
kelch-like 13
chr11_-_100770926 0.739 ENSMUST00000139341.1
ENSMUST00000017891.7
Ghdc

GH3 domain containing

chr11_+_55213783 0.731 ENSMUST00000108867.1
Slc36a1
solute carrier family 36 (proton/amino acid symporter), member 1
chr4_+_43578709 0.706 ENSMUST00000107886.2
ENSMUST00000117140.1
Rgp1

RGP1 retrograde golgi transport homolog (S. cerevisiae)

chr8_+_107150621 0.698 ENSMUST00000034400.3
Cyb5b
cytochrome b5 type B
chr2_+_4976113 0.696 ENSMUST00000167607.1
ENSMUST00000115010.2
Ucma

upper zone of growth plate and cartilage matrix associated

chr9_+_78051938 0.688 ENSMUST00000024104.7
Gcm1
glial cells missing homolog 1 (Drosophila)
chr2_+_32288317 0.684 ENSMUST00000131712.1
ENSMUST00000133113.1
ENSMUST00000081670.6
ENSMUST00000147707.1
ENSMUST00000129193.1
Golga2




golgi autoantigen, golgin subfamily a, 2




chr2_-_168767136 0.680 ENSMUST00000029061.5
ENSMUST00000103074.1
Sall4

sal-like 4 (Drosophila)

chr14_+_25459267 0.675 ENSMUST00000007961.8
Zmiz1
zinc finger, MIZ-type containing 1
chr5_-_45856496 0.674 ENSMUST00000087164.3
ENSMUST00000121573.1
Lcorl

ligand dependent nuclear receptor corepressor-like

chr14_+_31019159 0.651 ENSMUST00000112094.1
ENSMUST00000144009.1
Pbrm1

polybromo 1

chrX_+_8892376 0.647 ENSMUST00000064196.3
B630019K06Rik
RIKEN cDNA B630019K06 gene
chr4_+_101507947 0.644 ENSMUST00000149047.1
ENSMUST00000106929.3
Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr4_+_128654686 0.641 ENSMUST00000030588.6
ENSMUST00000136377.1
Phc2

polyhomeotic-like 2 (Drosophila)

chr14_+_118937925 0.617 ENSMUST00000022734.7
Dnajc3
DnaJ (Hsp40) homolog, subfamily C, member 3
chr10_+_82699007 0.598 ENSMUST00000020478.7
Hcfc2
host cell factor C2
chr4_-_43578636 0.597 ENSMUST00000130443.1
Gba2
glucosidase beta 2
chr13_+_13590402 0.595 ENSMUST00000110559.1
Lyst
lysosomal trafficking regulator
chr14_-_52237572 0.593 ENSMUST00000089752.4
Chd8
chromodomain helicase DNA binding protein 8
chr2_-_36136602 0.588 ENSMUST00000122456.1
Rbm18
RNA binding motif protein 18
chr2_+_157456917 0.584 ENSMUST00000109529.1
Src
Rous sarcoma oncogene
chr17_-_56005566 0.581 ENSMUST00000043785.6
Stap2
signal transducing adaptor family member 2
chr15_-_36794498 0.579 ENSMUST00000110361.1
ENSMUST00000022894.7
ENSMUST00000110359.1
Ywhaz


tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide


chr12_-_108702265 0.566 ENSMUST00000167978.1
ENSMUST00000021691.4
Degs2

degenerative spermatocyte homolog 2 (Drosophila), lipid desaturase

chr5_+_23787691 0.565 ENSMUST00000030852.6
ENSMUST00000120869.1
ENSMUST00000117783.1
ENSMUST00000115113.2
Rint1



RAD50 interactor 1



chr19_-_37207293 0.561 ENSMUST00000132580.1
ENSMUST00000079754.4
ENSMUST00000136286.1
ENSMUST00000126188.1
ENSMUST00000126781.1
Cpeb3




cytoplasmic polyadenylation element binding protein 3




chr16_+_11322915 0.559 ENSMUST00000115814.3
Snx29
sorting nexin 29
chr2_-_165388245 0.559 ENSMUST00000103084.3
Zfp334
zinc finger protein 334
chr13_+_24943144 0.555 ENSMUST00000021773.5
Gpld1
glycosylphosphatidylinositol specific phospholipase D1
chr9_-_100546053 0.555 ENSMUST00000116522.1
Nck1
non-catalytic region of tyrosine kinase adaptor protein 1
chr5_-_138619702 0.551 ENSMUST00000063262.4
Zfp68
zinc finger protein 68
chr14_+_25459206 0.549 ENSMUST00000162645.1
Zmiz1
zinc finger, MIZ-type containing 1
chr15_-_59374149 0.542 ENSMUST00000022976.4
E430025E21Rik
RIKEN cDNA E430025E21 gene
chr2_+_26319741 0.530 ENSMUST00000066889.6
Gpsm1
G-protein signalling modulator 1 (AGS3-like, C. elegans)
chr14_-_50870557 0.527 ENSMUST00000006444.7
Tep1
telomerase associated protein 1
chr9_-_44134481 0.521 ENSMUST00000180670.1
Gm10687
predicted gene 10687
chr17_-_46831413 0.519 ENSMUST00000040624.5
Gltscr1l
GLTSCR1-like
chr14_+_50870355 0.518 ENSMUST00000181697.1
ENSMUST00000181482.1
Gm26782

predicted gene, 26782

chr10_-_128744014 0.517 ENSMUST00000026414.7
Dgka
diacylglycerol kinase, alpha
chr4_-_41098174 0.509 ENSMUST00000055327.7
Aqp3
aquaporin 3
chr7_-_44236098 0.491 ENSMUST00000037220.4
1700028J19Rik
RIKEN cDNA 1700028J19 gene
chr12_+_69893105 0.489 ENSMUST00000021466.8
Atl1
atlastin GTPase 1
chr8_+_90828820 0.487 ENSMUST00000109614.2
ENSMUST00000048665.6
Chd9

chromodomain helicase DNA binding protein 9

chr6_-_106800051 0.486 ENSMUST00000013882.7
ENSMUST00000049675.4
ENSMUST00000113239.3
Crbn


cereblon


chr15_+_100038635 0.483 ENSMUST00000100203.3
Dip2b
DIP2 disco-interacting protein 2 homolog B (Drosophila)
chr9_-_121839460 0.482 ENSMUST00000135986.2
Ccdc13
coiled-coil domain containing 13
chr2_-_92459709 0.477 ENSMUST00000136718.1
ENSMUST00000067631.6
Slc35c1

solute carrier family 35, member C1

chr7_+_4922251 0.474 ENSMUST00000047309.5
Nat14
N-acetyltransferase 14
chr14_-_8172986 0.470 ENSMUST00000022268.8
Pdhb
pyruvate dehydrogenase (lipoamide) beta
chr12_+_70453095 0.464 ENSMUST00000021471.6
Tmx1
thioredoxin-related transmembrane protein 1
chr16_+_11322876 0.451 ENSMUST00000180792.1
Snx29
sorting nexin 29
chr6_-_38046994 0.440 ENSMUST00000096040.4
Svopl
SV2 related protein homolog (rat)-like
chr11_+_101316200 0.428 ENSMUST00000142640.1
ENSMUST00000019470.7
Psme3

proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)

chr14_-_52237791 0.425 ENSMUST00000149975.1
Chd8
chromodomain helicase DNA binding protein 8
chr8_+_70718534 0.424 ENSMUST00000179347.1
Gm3336
predicted gene 3336
chr6_-_67339661 0.424 ENSMUST00000117441.1
Il12rb2
interleukin 12 receptor, beta 2
chr8_+_94601928 0.417 ENSMUST00000060389.8
ENSMUST00000121101.1
Rspry1

ring finger and SPRY domain containing 1

chr4_-_152038568 0.414 ENSMUST00000030792.1
Tas1r1
taste receptor, type 1, member 1
chr10_-_79097560 0.413 ENSMUST00000039271.6
2610008E11Rik
RIKEN cDNA 2610008E11 gene
chr1_-_22315792 0.410 ENSMUST00000164877.1
Rims1
regulating synaptic membrane exocytosis 1
chr7_+_119690026 0.410 ENSMUST00000047045.8
Acsm4
acyl-CoA synthetase medium-chain family member 4
chr7_+_12927410 0.408 ENSMUST00000045870.4
2310014L17Rik
RIKEN cDNA 2310014L17 gene
chr9_-_44305595 0.406 ENSMUST00000034629.4
Hinfp
histone H4 transcription factor
chr17_-_35175995 0.403 ENSMUST00000173324.1
Aif1
allograft inflammatory factor 1
chr13_-_59557230 0.402 ENSMUST00000165370.1
ENSMUST00000109830.2
ENSMUST00000022040.6
ENSMUST00000171606.1
ENSMUST00000167096.1
ENSMUST00000166585.1
Agtpbp1





ATP/GTP binding protein 1





chr3_-_138131356 0.401 ENSMUST00000029805.8
Mttp
microsomal triglyceride transfer protein
chrX_-_165004829 0.397 ENSMUST00000114890.2
Gm17604
predicted gene, 17604
chr19_-_43752924 0.396 ENSMUST00000045562.5
Cox15
cytochrome c oxidase assembly protein 15
chr6_-_4747019 0.394 ENSMUST00000126151.1
ENSMUST00000133306.1
ENSMUST00000123907.1
Sgce


sarcoglycan, epsilon


chr4_-_45012287 0.391 ENSMUST00000055028.8
ENSMUST00000180217.1
ENSMUST00000107817.2
Zbtb5


zinc finger and BTB domain containing 5


chr19_-_28680077 0.389 ENSMUST00000162022.1
ENSMUST00000112612.2
Glis3

GLIS family zinc finger 3

chr7_+_45434876 0.386 ENSMUST00000107766.1
Gys1
glycogen synthase 1, muscle
chr10_+_44268328 0.377 ENSMUST00000039286.4
Atg5
autophagy related 5
chr9_+_107296843 0.366 ENSMUST00000167072.1
Cish
cytokine inducible SH2-containing protein
chr10_-_77902467 0.359 ENSMUST00000057608.4
Lrrc3
leucine rich repeat containing 3
chr8_+_25601591 0.356 ENSMUST00000155861.1
Whsc1l1
Wolf-Hirschhorn syndrome candidate 1-like 1 (human)
chr2_-_36136773 0.355 ENSMUST00000028251.3
Rbm18
RNA binding motif protein 18
chr3_-_107631681 0.354 ENSMUST00000064759.5
Strip1
striatin interacting protein 1
chr16_-_11176056 0.346 ENSMUST00000142389.1
ENSMUST00000138185.1
Zc3h7a

zinc finger CCCH type containing 7 A

chr8_+_3393018 0.345 ENSMUST00000004684.6
ENSMUST00000145394.1
Arhgef18

rho/rac guanine nucleotide exchange factor (GEF) 18

chr14_+_31019125 0.342 ENSMUST00000112095.1
ENSMUST00000112098.3
ENSMUST00000112106.1
ENSMUST00000146325.1
Pbrm1



polybromo 1



chr2_+_32721055 0.342 ENSMUST00000074248.4
Sh2d3c
SH2 domain containing 3C
chr3_+_107631322 0.339 ENSMUST00000106703.1
Gm10961
predicted gene 10961
chr10_-_127041513 0.338 ENSMUST00000116231.2
Mettl21b
methyltransferase like 21B
chr9_+_121710389 0.338 ENSMUST00000035113.9
Deb1
differentially expressed in B16F10 1
chr11_+_101316917 0.337 ENSMUST00000151385.1
Psme3
proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)
chr12_+_55239326 0.335 ENSMUST00000164243.1
Srp54c
signal recognition particle 54C
chr6_-_4747157 0.328 ENSMUST00000090686.4
ENSMUST00000115579.1
ENSMUST00000115577.2
ENSMUST00000101677.3
ENSMUST00000004750.8
Sgce




sarcoglycan, epsilon




chr7_+_45434833 0.326 ENSMUST00000003964.8
Gys1
glycogen synthase 1, muscle
chr8_-_85432841 0.326 ENSMUST00000047749.5
4921524J17Rik
RIKEN cDNA 4921524J17 gene
chr6_+_72414301 0.325 ENSMUST00000065906.7
Ggcx
gamma-glutamyl carboxylase
chr6_+_128399881 0.322 ENSMUST00000120405.1
Nrip2
nuclear receptor interacting protein 2
chr6_-_30509738 0.299 ENSMUST00000115160.3
Tmem209
transmembrane protein 209
chr4_+_106911517 0.296 ENSMUST00000072753.6
ENSMUST00000097934.3
Ssbp3

single-stranded DNA binding protein 3

chr4_-_45012093 0.295 ENSMUST00000131991.1
Zbtb5
zinc finger and BTB domain containing 5
chr15_+_34453285 0.291 ENSMUST00000060894.7
BC030476
cDNA sequence BC030476
chr1_+_136467958 0.289 ENSMUST00000047817.6
Kif14
kinesin family member 14
chr19_-_32712287 0.289 ENSMUST00000070210.4
Atad1
ATPase family, AAA domain containing 1
chr15_-_74997634 0.286 ENSMUST00000023248.6
Ly6a
lymphocyte antigen 6 complex, locus A
chr5_-_100373484 0.285 ENSMUST00000182433.1
Sec31a
Sec31 homolog A (S. cerevisiae)
chr4_-_43578824 0.283 ENSMUST00000030189.7
Gba2
glucosidase beta 2
chr4_-_123718181 0.283 ENSMUST00000137312.1
ENSMUST00000106206.1
Ndufs5

NADH dehydrogenase (ubiquinone) Fe-S protein 5

chr3_-_127896271 0.266 ENSMUST00000057198.7
5730508B09Rik
RIKEN cDNA 5730508B09 gene
chr15_+_38661904 0.266 ENSMUST00000022904.6
Atp6v1c1
ATPase, H+ transporting, lysosomal V1 subunit C1
chr14_-_47411666 0.259 ENSMUST00000111778.3
Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr7_+_28440927 0.247 ENSMUST00000078845.6
Gmfg
glia maturation factor, gamma
chr17_+_34398802 0.247 ENSMUST00000114175.1
ENSMUST00000078615.5
ENSMUST00000139063.1
ENSMUST00000097348.2
BC051142



cDNA sequence BC051142



chr17_-_71475285 0.243 ENSMUST00000127430.1
Smchd1
SMC hinge domain containing 1
chr3_+_27317028 0.242 ENSMUST00000046383.5
ENSMUST00000174840.1
Tnfsf10

tumor necrosis factor (ligand) superfamily, member 10

chr6_+_128399766 0.240 ENSMUST00000001561.5
Nrip2
nuclear receptor interacting protein 2
chr11_+_53567361 0.239 ENSMUST00000057330.8
ENSMUST00000120613.2
ENSMUST00000173744.1
ENSMUST00000118353.2
Kif3a



kinesin family member 3A



chr11_-_70969953 0.238 ENSMUST00000108530.1
ENSMUST00000035283.4
ENSMUST00000108531.1
Nup88


nucleoporin 88


chr2_+_36136384 0.234 ENSMUST00000028250.2
Mrrf
mitochondrial ribosome recycling factor
chr2_+_82053222 0.232 ENSMUST00000047527.7
Zfp804a
zinc finger protein 804A
chr11_+_117986292 0.227 ENSMUST00000132676.1
Pgs1
phosphatidylglycerophosphate synthase 1
chr6_+_48589560 0.225 ENSMUST00000181661.1
Gm5111
predicted gene 5111
chr6_-_30509706 0.214 ENSMUST00000064330.6
ENSMUST00000102991.2
ENSMUST00000115157.1
ENSMUST00000148638.1
Tmem209



transmembrane protein 209



chr19_-_20727533 0.210 ENSMUST00000025656.3
Aldh1a7
aldehyde dehydrogenase family 1, subfamily A7
chr13_-_74208661 0.210 ENSMUST00000035934.5
Exoc3
exocyst complex component 3
chr5_+_150673739 0.208 ENSMUST00000016569.4
ENSMUST00000038900.8
Pds5b

PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)

chr14_+_79587691 0.204 ENSMUST00000054908.8
Sugt1
SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
chr8_+_94214567 0.199 ENSMUST00000079961.6
Nup93
nucleoporin 93
chr8_+_33732049 0.188 ENSMUST00000167264.1
Gtf2e2
general transcription factor II E, polypeptide 2 (beta subunit)
chr5_-_137046026 0.186 ENSMUST00000144303.1
ENSMUST00000111080.1
Ap1s1

adaptor protein complex AP-1, sigma 1

chr2_+_181319806 0.181 ENSMUST00000153112.1
Rtel1
regulator of telomere elongation helicase 1
chr10_-_76442758 0.180 ENSMUST00000001179.5
Pcnt
pericentrin (kendrin)
chr14_+_16249259 0.179 ENSMUST00000022310.6
Ngly1
N-glycanase 1
chr7_-_109986250 0.177 ENSMUST00000119929.1
Tmem41b
transmembrane protein 41B
chr14_-_54870913 0.177 ENSMUST00000146642.1
Homez
homeodomain leucine zipper-encoding gene
chr11_-_59839828 0.172 ENSMUST00000019517.3
Cops3
COP9 (constitutive photomorphogenic) homolog, subunit 3 (Arabidopsis thaliana)
chr4_-_129662442 0.165 ENSMUST00000003828.4
Kpna6
karyopherin (importin) alpha 6
chr9_+_109051090 0.163 ENSMUST00000059097.8
Shisa5
shisa homolog 5 (Xenopus laevis)
chr8_+_70724064 0.161 ENSMUST00000034307.7
ENSMUST00000110095.2
Pde4c

phosphodiesterase 4C, cAMP specific

chr17_+_35861318 0.159 ENSMUST00000074259.8
ENSMUST00000174873.1
Nrm

nurim (nuclear envelope membrane protein)

chr6_+_52713729 0.154 ENSMUST00000080723.4
ENSMUST00000149588.1
Tax1bp1

Tax1 (human T cell leukemia virus type I) binding protein 1

chr12_+_76837408 0.153 ENSMUST00000041008.9
Fntb
farnesyltransferase, CAAX box, beta
chr11_-_83578496 0.151 ENSMUST00000019266.5
Ccl9
chemokine (C-C motif) ligand 9
chr8_+_25602236 0.150 ENSMUST00000146919.1
ENSMUST00000142395.1
ENSMUST00000139966.1
Whsc1l1


Wolf-Hirschhorn syndrome candidate 1-like 1 (human)


chr4_-_46196298 0.149 ENSMUST00000142380.1
ENSMUST00000058232.4
ENSMUST00000030013.5
Xpa


xeroderma pigmentosum, complementation group A


chr1_+_134405984 0.147 ENSMUST00000173908.1
Cyb5r1
cytochrome b5 reductase 1
chr2_-_181592733 0.143 ENSMUST00000108789.2
ENSMUST00000153998.1
Znf512b

zinc finger protein 512B

chr3_-_37125943 0.140 ENSMUST00000029275.5
Il2
interleukin 2
chr3_+_53845086 0.136 ENSMUST00000108014.1
Gm10985
predicted gene 10985

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 9.1 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.7 2.1 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.6 3.2 GO:0035262 gonad morphogenesis(GO:0035262)
0.6 3.8 GO:0003383 apical constriction(GO:0003383)
0.5 1.5 GO:0046671 negative regulation of retinal cell programmed cell death(GO:0046671)
0.4 1.3 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.4 1.1 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.3 1.7 GO:0015867 ATP transport(GO:0015867)
0.3 1.0 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.2 1.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.2 1.5 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.2 0.9 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.2 1.9 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.2 0.6 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.2 0.8 GO:0044330 canonical Wnt signaling pathway involved in positive regulation of wound healing(GO:0044330) lactic acid secretion(GO:0046722) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.2 0.6 GO:0006667 sphinganine metabolic process(GO:0006667)
0.2 0.6 GO:0072425 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.2 0.6 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.2 0.6 GO:0002430 complement receptor mediated signaling pathway(GO:0002430) GPI anchor release(GO:0006507)
0.2 1.4 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.2 0.9 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.2 1.2 GO:0007296 vitellogenesis(GO:0007296)
0.2 1.6 GO:0030259 lipid glycosylation(GO:0030259)
0.2 0.7 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.2 0.5 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.2 0.8 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.2 0.8 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 0.6 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.1 0.4 GO:0014738 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.1 0.4 GO:0071500 aggrephagy(GO:0035973) cellular response to nitrosative stress(GO:0071500)
0.1 0.6 GO:0090168 Golgi reassembly(GO:0090168)
0.1 0.3 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 0.1 GO:0016925 protein sumoylation(GO:0016925)
0.1 0.6 GO:0072318 clathrin coat disassembly(GO:0072318)
0.1 0.4 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.1 0.7 GO:0015808 L-alanine transport(GO:0015808)
0.1 1.4 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 0.4 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.1 0.8 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.1 0.3 GO:2000744 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.1 0.7 GO:0060050 positive regulation of protein glycosylation(GO:0060050) spindle assembly involved in meiosis(GO:0090306)
0.1 0.8 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.1 1.0 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.1 0.1 GO:0061373 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373)
0.1 0.8 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 0.2 GO:0060821 inactivation of X chromosome by DNA methylation(GO:0060821)
0.1 0.4 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 0.2 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.1 0.3 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.1 0.7 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.1 0.1 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.1 0.1 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.1 0.5 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 2.4 GO:0006739 NADP metabolic process(GO:0006739)
0.1 1.3 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.1 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0 0.2 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.8 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 1.1 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 1.1 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.2 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0 0.2 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.2 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 1.5 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.2 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.0 0.5 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 0.3 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.4 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.3 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.4 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.1 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.9 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.9 GO:0007099 centriole replication(GO:0007099)
0.0 1.6 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.0 1.6 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.1 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.4 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.2 GO:0042573 retinoic acid metabolic process(GO:0042573)
0.0 0.1 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.2 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.2 GO:0006517 protein deglycosylation(GO:0006517)
0.0 0.2 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.5 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.2 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.1 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.0 0.6 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.9 GO:0051453 regulation of intracellular pH(GO:0051453)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.8 GO:0033269 internode region of axon(GO:0033269)
0.2 0.7 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.2 0.8 GO:0008537 proteasome activator complex(GO:0008537)
0.2 0.6 GO:0070939 Dsl1p complex(GO:0070939)
0.2 0.7 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 3.6 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.9 GO:0098536 deuterosome(GO:0098536)
0.1 0.4 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 0.3 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.1 1.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.4 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.1 0.2 GO:0016939 kinesin II complex(GO:0016939)
0.1 0.2 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 0.5 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 0.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 2.0 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.8 GO:0036038 MKS complex(GO:0036038)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.8 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 3.6 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.7 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 1.1 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.5 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.2 GO:0001740 Barr body(GO:0001740)
0.0 0.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 1.1 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 1.0 GO:0097546 ciliary base(GO:0097546)
0.0 0.4 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.5 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.1 GO:0097450 astrocyte end-foot(GO:0097450)
0.0 0.8 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.8 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.1 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0097208 alveolar lamellar body(GO:0097208)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.7 GO:0016235 aggresome(GO:0016235)
0.0 0.6 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0000145 exocyst(GO:0000145)
0.0 0.7 GO:0016234 inclusion body(GO:0016234)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.5 GO:0000792 heterochromatin(GO:0000792)
0.0 0.4 GO:0015030 Cajal body(GO:0015030)
0.0 0.2 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.2 GO:0005652 nuclear lamina(GO:0005652)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.4 1.2 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.4 2.6 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.3 1.0 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.3 0.9 GO:0004348 glucosylceramidase activity(GO:0004348)
0.3 2.5 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.3 2.1 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.2 0.7 GO:0015173 hydrogen:amino acid symporter activity(GO:0005280) aromatic amino acid transmembrane transporter activity(GO:0015173)
0.2 1.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 0.6 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.2 2.2 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.2 1.1 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.2 1.8 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 0.4 GO:0008527 taste receptor activity(GO:0008527)
0.1 0.8 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.4 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.1 0.5 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.4 GO:0019776 Atg8 ligase activity(GO:0019776)
0.1 1.3 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.1 2.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.8 GO:0035326 enhancer binding(GO:0035326)
0.1 1.9 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.1 0.5 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 0.6 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.8 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.7 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 0.7 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 3.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 1.4 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.1 0.6 GO:0071253 connexin binding(GO:0071253)
0.1 0.8 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.6 GO:0004630 phospholipase D activity(GO:0004630)
0.1 1.4 GO:0051787 misfolded protein binding(GO:0051787)
0.1 2.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 1.0 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.5 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.9 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.8 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.1 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.5 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.8 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.9 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.2 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.0 0.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.5 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.1 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.4 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.4 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.8 GO:0070888 E-box binding(GO:0070888)
0.0 1.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.7 GO:0020037 heme binding(GO:0020037)
0.0 0.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.2 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 1.0 ST_STAT3_PATHWAY STAT3 Pathway
0.1 0.7 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 3.8 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.0 0.6 PID_IL27_PATHWAY IL27-mediated signaling events
0.0 0.8 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 1.3 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 0.8 PID_CD40_PATHWAY CD40/CD40L signaling
0.0 1.3 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.6 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.7 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.7 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 1.6 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.2 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 0.3 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 0.2 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.0 0.6 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.6 PID_PLK1_PATHWAY PLK1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.1 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.2 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 2.6 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 0.5 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 0.9 REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 1.2 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.8 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.7 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 2.7 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 1.6 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.4 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.5 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.3 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.8 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.4 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.6 REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.9 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.6 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.8 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.2 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.8 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.9 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.9 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.4 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.5 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.5 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.4 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.3 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.1 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.1 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.0 1.0 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.5 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules