Motif ID: Myb

Z-value: 2.010


Transcription factors associated with Myb:

Gene SymbolEntrez IDGene Name
Myb ENSMUSG00000019982.8 Myb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mybmm10_v2_chr10_-_21160925_211609840.846.6e-12Click!


Activity profile for motif Myb.

activity profile for motif Myb


Sorted Z-values histogram for motif Myb

Sorted Z-values for motif Myb



Network of associatons between targets according to the STRING database.



First level regulatory network of Myb

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_+_60925612 14.610 ENSMUST00000102888.3
ENSMUST00000025519.4
Camk2a

calcium/calmodulin-dependent protein kinase II alpha

chr2_+_118814237 11.459 ENSMUST00000028803.7
ENSMUST00000126045.1
Knstrn

kinetochore-localized astrin/SPAG5 binding

chr11_-_69921057 11.289 ENSMUST00000108609.1
ENSMUST00000108608.1
ENSMUST00000164359.1
Eif5a


eukaryotic translation initiation factor 5A


chr4_-_118437331 11.258 ENSMUST00000006565.6
Cdc20
cell division cycle 20
chr2_+_118814195 10.784 ENSMUST00000110842.1
Knstrn
kinetochore-localized astrin/SPAG5 binding
chr11_-_69920892 10.495 ENSMUST00000152589.1
ENSMUST00000108612.1
ENSMUST00000108611.1
Eif5a


eukaryotic translation initiation factor 5A


chr10_+_84838143 10.273 ENSMUST00000095388.4
Rfx4
regulatory factor X, 4 (influences HLA class II expression)
chr2_+_118813995 9.778 ENSMUST00000134661.1
Knstrn
kinetochore-localized astrin/SPAG5 binding
chr16_-_46496955 9.599 ENSMUST00000023335.6
ENSMUST00000023334.8
Pvrl3

poliovirus receptor-related 3

chr2_-_127831817 8.556 ENSMUST00000028858.7
Bub1
budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)
chr14_-_54577578 8.360 ENSMUST00000054487.8
Ajuba
ajuba LIM protein
chr9_+_106281061 8.358 ENSMUST00000072206.6
Poc1a
POC1 centriolar protein homolog A (Chlamydomonas)
chr14_+_46760526 8.282 ENSMUST00000067426.4
Cdkn3
cyclin-dependent kinase inhibitor 3
chr6_+_124829540 8.187 ENSMUST00000150120.1
Cdca3
cell division cycle associated 3
chr19_+_36409719 8.169 ENSMUST00000062389.5
Pcgf5
polycomb group ring finger 5
chr2_-_37703275 8.034 ENSMUST00000072186.5
Strbp
spermatid perinuclear RNA binding protein
chr17_-_70851189 7.917 ENSMUST00000059775.8
Tgif1
TGFB-induced factor homeobox 1
chr11_-_69921329 7.883 ENSMUST00000108613.3
ENSMUST00000043419.3
ENSMUST00000070996.4
Eif5a


eukaryotic translation initiation factor 5A


chr6_+_124829582 7.774 ENSMUST00000024270.7
Cdca3
cell division cycle associated 3
chr10_-_95564167 7.516 ENSMUST00000020217.5
Nudt4
nudix (nucleoside diphosphate linked moiety X)-type motif 4
chr16_-_46496772 7.410 ENSMUST00000149901.1
ENSMUST00000096052.2
Pvrl3

poliovirus receptor-related 3

chr7_+_126861947 6.842 ENSMUST00000037248.3
Hirip3
HIRA interacting protein 3
chr9_+_72438534 6.816 ENSMUST00000034746.8
Mns1
meiosis-specific nuclear structural protein 1
chr11_-_69921190 6.748 ENSMUST00000108607.1
Eif5a
eukaryotic translation initiation factor 5A
chr5_+_123749696 6.715 ENSMUST00000031366.7
Kntc1
kinetochore associated 1
chr16_+_64851991 6.517 ENSMUST00000067744.7
Cggbp1
CGG triplet repeat binding protein 1
chr9_+_72438519 6.351 ENSMUST00000184604.1
Mns1
meiosis-specific nuclear structural protein 1
chr1_-_191575534 6.265 ENSMUST00000027933.5
Dtl
denticleless homolog (Drosophila)
chr5_+_33658567 5.958 ENSMUST00000114426.3
Tacc3
transforming, acidic coiled-coil containing protein 3
chr17_-_33890584 5.877 ENSMUST00000114361.2
ENSMUST00000173492.1
Kifc1

kinesin family member C1

chr6_+_117906755 5.867 ENSMUST00000170346.1
ENSMUST00000179224.1
ENSMUST00000035493.7
Hnrnpf


heterogeneous nuclear ribonucleoprotein F


chr4_-_107684228 5.865 ENSMUST00000069271.4
Dmrtb1
DMRT-like family B with proline-rich C-terminal, 1
chr15_-_88978958 5.863 ENSMUST00000042594.6
ENSMUST00000109368.1
Mlc1

megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human)

chr7_+_126862431 5.855 ENSMUST00000132808.1
Hirip3
HIRA interacting protein 3
chr2_-_172370506 5.830 ENSMUST00000109139.1
ENSMUST00000028997.7
ENSMUST00000109140.3
Aurka


aurora kinase A


chr7_-_144939823 5.781 ENSMUST00000093962.4
Ccnd1
cyclin D1
chrX_+_134308084 5.538 ENSMUST00000081064.5
ENSMUST00000101251.1
ENSMUST00000129782.1
Cenpi


centromere protein I


chr10_+_128058974 5.428 ENSMUST00000084771.2
Ptges3
prostaglandin E synthase 3 (cytosolic)
chr5_+_33658123 5.333 ENSMUST00000074849.6
ENSMUST00000079534.4
Tacc3

transforming, acidic coiled-coil containing protein 3

chr6_+_117906809 5.294 ENSMUST00000177918.1
ENSMUST00000163168.2
Hnrnpf

heterogeneous nuclear ribonucleoprotein F

chrX_-_102157065 5.209 ENSMUST00000056904.2
Ercc6l
excision repair cross-complementing rodent repair deficiency complementation group 6 like
chr8_-_45382198 5.201 ENSMUST00000093526.6
Fam149a
family with sequence similarity 149, member A
chr5_+_33658550 5.055 ENSMUST00000152847.1
Tacc3
transforming, acidic coiled-coil containing protein 3
chr5_-_8422582 5.030 ENSMUST00000168500.1
ENSMUST00000002368.9
Dbf4

DBF4 homolog (S. cerevisiae)

chr13_+_51645232 5.029 ENSMUST00000075853.5
Cks2
CDC28 protein kinase regulatory subunit 2
chr17_-_33890539 5.012 ENSMUST00000173386.1
Kifc1
kinesin family member C1
chr5_-_8422695 4.980 ENSMUST00000171808.1
Dbf4
DBF4 homolog (S. cerevisiae)
chr1_+_57995971 4.877 ENSMUST00000027202.8
Sgol2
shugoshin-like 2 (S. pombe)
chr10_+_128058947 4.870 ENSMUST00000052798.7
Ptges3
prostaglandin E synthase 3 (cytosolic)
chrX_+_58030999 4.821 ENSMUST00000088631.4
ENSMUST00000088629.3
Zic3

zinc finger protein of the cerebellum 3

chr11_-_69980468 4.787 ENSMUST00000143175.1
Elp5
elongator acetyltransferase complex subunit 5
chr4_-_95052188 4.707 ENSMUST00000107094.1
Jun
Jun oncogene
chr8_+_83955507 4.697 ENSMUST00000005607.8
Asf1b
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr7_+_46847128 4.558 ENSMUST00000005051.4
Ldha
lactate dehydrogenase A
chr12_+_111971545 4.514 ENSMUST00000079009.5
Tdrd9
tudor domain containing 9
chr14_+_63436394 4.485 ENSMUST00000121288.1
Fam167a
family with sequence similarity 167, member A
chr17_+_26917091 4.445 ENSMUST00000078961.4
Kifc5b
kinesin family member C5B
chr11_-_106999482 4.422 ENSMUST00000018506.6
Kpna2
karyopherin (importin) alpha 2
chr19_-_41802028 4.414 ENSMUST00000026150.8
ENSMUST00000177495.1
ENSMUST00000163265.1
Arhgap19


Rho GTPase activating protein 19


chr8_+_12385769 4.353 ENSMUST00000080795.8
Gm5607
predicted gene 5607
chr18_+_34625009 4.323 ENSMUST00000166044.1
Kif20a
kinesin family member 20A
chr2_+_119047116 4.311 ENSMUST00000152380.1
ENSMUST00000099542.2
Casc5

cancer susceptibility candidate 5

chr11_+_23666007 4.215 ENSMUST00000058163.4
Pus10
pseudouridylate synthase 10
chr5_+_108132885 4.154 ENSMUST00000047677.7
Ccdc18
coiled-coil domain containing 18
chr11_-_106999369 4.143 ENSMUST00000106768.1
ENSMUST00000144834.1
Kpna2

karyopherin (importin) alpha 2

chr3_+_137864573 4.124 ENSMUST00000174561.1
ENSMUST00000173790.1
H2afz

H2A histone family, member Z

chr1_+_191821444 4.088 ENSMUST00000027931.7
Nek2
NIMA (never in mitosis gene a)-related expressed kinase 2
chr8_+_85432686 4.063 ENSMUST00000180883.1
1700051O22Rik
RIKEN cDNA 1700051O22 Gene
chr8_+_75033673 3.959 ENSMUST00000078847.5
ENSMUST00000165630.1
Tom1

target of myb1 homolog (chicken)

chr1_-_44101982 3.951 ENSMUST00000127923.1
Tex30
testis expressed 30
chr11_+_69935894 3.928 ENSMUST00000149194.1
Ybx2
Y box protein 2
chr8_+_83715177 3.821 ENSMUST00000019576.8
Ddx39
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39
chr9_+_107547288 3.766 ENSMUST00000010188.7
Zmynd10
zinc finger, MYND domain containing 10
chr19_-_9135603 3.761 ENSMUST00000049948.5
Asrgl1
asparaginase like 1
chr2_-_57114970 3.735 ENSMUST00000028166.2
Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr16_+_91269759 3.718 ENSMUST00000056882.5
Olig1
oligodendrocyte transcription factor 1
chr4_-_83486453 3.633 ENSMUST00000107214.2
ENSMUST00000107215.2
ENSMUST00000030207.8
Psip1


PC4 and SFRS1 interacting protein 1


chr7_-_79149042 3.583 ENSMUST00000032825.8
ENSMUST00000107409.3
Mfge8

milk fat globule-EGF factor 8 protein

chr5_-_33652296 3.571 ENSMUST00000151081.1
ENSMUST00000101354.3
Slbp

stem-loop binding protein

chr1_-_44102362 3.471 ENSMUST00000147571.1
ENSMUST00000027215.5
ENSMUST00000147661.1
Tex30


testis expressed 30


chr18_+_34624621 3.460 ENSMUST00000167161.1
Kif20a
kinesin family member 20A
chr14_-_62761112 3.388 ENSMUST00000053959.6
Ints6
integrator complex subunit 6
chr1_-_44102341 3.297 ENSMUST00000128190.1
Tex30
testis expressed 30
chr17_+_8165501 3.238 ENSMUST00000097419.3
ENSMUST00000024636.8
Fgfr1op

Fgfr1 oncogene partner

chr18_+_60925644 3.174 ENSMUST00000115297.1
Camk2a
calcium/calmodulin-dependent protein kinase II alpha
chr1_-_57377476 3.172 ENSMUST00000181949.1
4930558J18Rik
RIKEN cDNA 4930558J18 gene
chr1_-_44102433 3.113 ENSMUST00000129702.1
ENSMUST00000149502.1
ENSMUST00000156392.1
ENSMUST00000150911.1
Tex30



testis expressed 30



chr19_-_29325313 3.113 ENSMUST00000052380.4
Insl6
insulin-like 6
chr13_+_119428888 3.098 ENSMUST00000026520.7
Paip1
polyadenylate binding protein-interacting protein 1
chr4_-_83486178 3.064 ENSMUST00000130626.1
Psip1
PC4 and SFRS1 interacting protein 1
chrX_+_58030622 3.056 ENSMUST00000088627.4
Zic3
zinc finger protein of the cerebellum 3
chr9_+_31030621 3.055 ENSMUST00000115222.2
Zbtb44
zinc finger and BTB domain containing 44
chr8_+_83715504 3.022 ENSMUST00000109810.1
Ddx39
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39
chr2_+_119047129 3.015 ENSMUST00000153300.1
ENSMUST00000028799.5
Casc5

cancer susceptibility candidate 5

chr1_-_44102414 3.014 ENSMUST00000143327.1
ENSMUST00000133677.1
Tex30

testis expressed 30

chr1_+_87264345 2.888 ENSMUST00000118687.1
ENSMUST00000027472.6
Efhd1

EF hand domain containing 1

chr4_-_116627921 2.846 ENSMUST00000030456.7
Nasp
nuclear autoantigenic sperm protein (histone-binding)
chr13_+_119428583 2.803 ENSMUST00000109203.2
Paip1
polyadenylate binding protein-interacting protein 1
chr4_-_148626756 2.762 ENSMUST00000105699.1
Tardbp
TAR DNA binding protein
chr11_+_23665615 2.738 ENSMUST00000109525.1
ENSMUST00000020520.4
Pus10

pseudouridylate synthase 10

chr14_-_13961202 2.665 ENSMUST00000065865.8
Thoc7
THO complex 7 homolog (Drosophila)
chr6_-_131388417 2.618 ENSMUST00000032309.6
ENSMUST00000087865.2
Ybx3

Y box protein 3

chrX_+_56786527 2.617 ENSMUST00000144600.1
Fhl1
four and a half LIM domains 1
chr17_-_80062199 2.562 ENSMUST00000184635.1
Hnrnpll
heterogeneous nuclear ribonucleoprotein L-like
chr8_+_83389846 2.561 ENSMUST00000002259.6
Clgn
calmegin
chr18_-_46728342 2.483 ENSMUST00000035804.7
Cdo1
cysteine dioxygenase 1, cytosolic
chr17_-_80207299 2.468 ENSMUST00000063417.9
Srsf7
serine/arginine-rich splicing factor 7
chr11_-_23665862 2.412 ENSMUST00000020523.3
Pex13
peroxisomal biogenesis factor 13
chr14_-_55671873 2.378 ENSMUST00000163750.1
ENSMUST00000010520.8
Nedd8

neural precursor cell expressed, developmentally down-regulated gene 8

chr18_+_35536539 2.370 ENSMUST00000081864.3
Gm5239
predicted pseudogene 5239
chr11_+_69935796 2.356 ENSMUST00000018698.5
Ybx2
Y box protein 2
chr5_+_122372451 2.327 ENSMUST00000031420.4
Gpn3
GPN-loop GTPase 3
chr17_+_48409980 2.321 ENSMUST00000167180.1
ENSMUST00000046651.6
Oard1

O-acyl-ADP-ribose deacylase 1

chr8_+_83715239 2.239 ENSMUST00000172396.1
Ddx39
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39
chr5_+_90367204 2.233 ENSMUST00000068250.3
Gm9958
predicted gene 9958
chr10_-_41809607 2.227 ENSMUST00000019951.9
Cep57l1
centrosomal protein 57-like 1
chr9_-_121839460 2.210 ENSMUST00000135986.2
Ccdc13
coiled-coil domain containing 13
chr5_+_76183880 2.181 ENSMUST00000031144.7
Tmem165
transmembrane protein 165
chr4_-_116627478 2.179 ENSMUST00000081182.4
ENSMUST00000030457.5
Nasp

nuclear autoantigenic sperm protein (histone-binding)

chr3_+_146404631 2.162 ENSMUST00000106153.2
ENSMUST00000039021.4
ENSMUST00000106151.1
ENSMUST00000149262.1
Ssx2ip



synovial sarcoma, X breakpoint 2 interacting protein



chr18_-_67641329 2.144 ENSMUST00000097542.2
Cep76
centrosomal protein 76
chr4_-_3973581 2.063 ENSMUST00000089430.4
Gm11808
predicted gene 11808
chr3_+_103020546 2.003 ENSMUST00000029446.8
Csde1
cold shock domain containing E1, RNA binding
chr5_-_108132577 1.994 ENSMUST00000061203.6
ENSMUST00000002837.4
Tmed5

transmembrane emp24 protein transport domain containing 5

chr11_-_116853083 1.927 ENSMUST00000092404.6
Srsf2
serine/arginine-rich splicing factor 2
chr11_+_96789149 1.927 ENSMUST00000093943.3
Cbx1
chromobox 1
chr17_-_80062333 1.918 ENSMUST00000061331.7
Hnrnpll
heterogeneous nuclear ribonucleoprotein L-like
chr15_+_57912199 1.918 ENSMUST00000022992.6
Tbc1d31
TBC1 domain family, member 31
chr6_+_48593883 1.916 ENSMUST00000154010.1
ENSMUST00000163452.1
ENSMUST00000118229.1
ENSMUST00000009420.8
Repin1



replication initiator 1



chr11_+_70525361 1.900 ENSMUST00000018430.6
Psmb6
proteasome (prosome, macropain) subunit, beta type 6
chr4_+_128993224 1.898 ENSMUST00000030583.6
ENSMUST00000102604.4
Ak2

adenylate kinase 2

chr11_+_53770014 1.854 ENSMUST00000108920.2
ENSMUST00000140866.1
ENSMUST00000108922.1
Irf1


interferon regulatory factor 1


chr7_-_126861828 1.854 ENSMUST00000106343.1
Ino80e
INO80 complex subunit E
chr7_-_18910391 1.843 ENSMUST00000150065.1
ENSMUST00000098780.3
Ccdc61

coiled-coil domain containing 61

chr2_-_25224653 1.821 ENSMUST00000043584.4
Tubb4b
tubulin, beta 4B class IVB
chr14_+_64950037 1.767 ENSMUST00000043914.5
Ints9
integrator complex subunit 9
chr9_-_96889381 1.766 ENSMUST00000112951.2
ENSMUST00000126411.1
ENSMUST00000078478.1
ENSMUST00000119141.1
ENSMUST00000120101.1
Acpl2




acid phosphatase-like 2




chr1_+_88227005 1.759 ENSMUST00000061013.6
ENSMUST00000113130.1
Mroh2a

maestro heat-like repeat family member 2A

chr3_+_116594959 1.759 ENSMUST00000029571.8
Sass6
spindle assembly 6 homolog (C. elegans)
chr11_-_69666062 1.754 ENSMUST00000108654.2
ENSMUST00000018918.5
Cd68

CD68 antigen

chr6_+_57580992 1.743 ENSMUST00000031817.8
Herc6
hect domain and RLD 6
chr6_-_28261907 1.735 ENSMUST00000115320.1
ENSMUST00000123098.1
ENSMUST00000115321.2
ENSMUST00000155494.1
Zfp800



zinc finger protein 800



chr5_+_76588663 1.706 ENSMUST00000121979.1
Cep135
centrosomal protein 135
chr14_+_47472547 1.691 ENSMUST00000168833.1
ENSMUST00000163324.1
ENSMUST00000043112.7
Fbxo34


F-box protein 34


chr6_+_116264186 1.682 ENSMUST00000036503.7
ENSMUST00000112900.3
Zfand4

zinc finger, AN1-type domain 4

chr11_+_96789213 1.673 ENSMUST00000079702.3
Cbx1
chromobox 1
chr14_+_57798182 1.669 ENSMUST00000111269.1
Sap18
Sin3-associated polypeptide 18
chr6_+_119479668 1.669 ENSMUST00000032094.5
Fbxl14
F-box and leucine-rich repeat protein 14
chr7_-_18910377 1.666 ENSMUST00000139077.1
Ccdc61
coiled-coil domain containing 61
chr11_-_109473220 1.664 ENSMUST00000070872.6
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr14_+_47472628 1.638 ENSMUST00000095941.2
Fbxo34
F-box protein 34
chr19_-_10457447 1.623 ENSMUST00000171400.2
Lrrc10b
leucine rich repeat containing 10B
chr5_+_135369942 1.615 ENSMUST00000000940.8
Nsun5
NOL1/NOP2/Sun domain family, member 5
chr1_+_17727034 1.596 ENSMUST00000159958.1
ENSMUST00000160305.1
ENSMUST00000095075.4
Crispld1


cysteine-rich secretory protein LCCL domain containing 1


chr1_+_137966529 1.587 ENSMUST00000182158.1
A430106G13Rik
RIKEN cDNA A430106G13 gene
chr2_+_157279065 1.586 ENSMUST00000029171.5
Rpn2
ribophorin II
chr15_-_81399594 1.568 ENSMUST00000023039.8
St13
suppression of tumorigenicity 13
chr8_+_106935720 1.564 ENSMUST00000047425.3
Sntb2
syntrophin, basic 2
chr2_+_29890534 1.552 ENSMUST00000113764.3
Odf2
outer dense fiber of sperm tails 2
chr5_-_33652339 1.541 ENSMUST00000075670.6
Slbp
stem-loop binding protein
chr16_+_34690548 1.535 ENSMUST00000023532.6
Ccdc14
coiled-coil domain containing 14
chr15_+_100228229 1.526 ENSMUST00000171869.1
Atf1
activating transcription factor 1
chr6_+_83156401 1.511 ENSMUST00000032106.4
1700003E16Rik
RIKEN cDNA 1700003E16 gene
chr7_+_13024120 1.510 ENSMUST00000005705.7
Trim28
tripartite motif-containing 28
chr6_+_125192154 1.504 ENSMUST00000032485.5
Mrpl51
mitochondrial ribosomal protein L51
chr12_-_21417591 1.498 ENSMUST00000135088.1
Ywhaq
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
chr19_+_3851972 1.495 ENSMUST00000025760.6
Chka
choline kinase alpha
chr17_+_31564749 1.487 ENSMUST00000175806.1
ENSMUST00000097352.3
Pknox1

Pbx/knotted 1 homeobox

chr13_-_100650981 1.474 ENSMUST00000022136.6
ENSMUST00000177848.1
Rad17

RAD17 homolog (S. pombe)

chr10_-_63339023 1.473 ENSMUST00000177694.1
ENSMUST00000020257.6
ENSMUST00000105442.2
Sirt1


sirtuin 1


chr7_-_16387791 1.464 ENSMUST00000094815.3
Sae1
SUMO1 activating enzyme subunit 1
chr5_-_108132513 1.424 ENSMUST00000119784.1
ENSMUST00000117759.1
Tmed5

transmembrane emp24 protein transport domain containing 5

chr14_-_31251194 1.422 ENSMUST00000022459.3
Phf7
PHD finger protein 7
chr9_-_19928282 1.399 ENSMUST00000082002.5
Gm7808
predicted pseudogene 7808
chr4_+_40722912 1.399 ENSMUST00000164233.1
ENSMUST00000137246.1
ENSMUST00000125442.1
Dnaja1


DnaJ (Hsp40) homolog, subfamily A, member 1


chr1_-_45503282 1.396 ENSMUST00000086430.4
Col5a2
collagen, type V, alpha 2
chr13_-_96542479 1.392 ENSMUST00000022172.4
Polk
polymerase (DNA directed), kappa
chr11_+_80383279 1.392 ENSMUST00000165565.1
ENSMUST00000017567.7
Zfp207

zinc finger protein 207

chr2_+_157279026 1.388 ENSMUST00000116380.2
Rpn2
ribophorin II
chr7_+_126695942 1.384 ENSMUST00000106369.1
Bola2
bolA-like 2 (E. coli)
chr11_+_96789118 1.366 ENSMUST00000018810.3
Cbx1
chromobox 1
chr6_-_125191535 1.359 ENSMUST00000043848.4
Ncapd2
non-SMC condensin I complex, subunit D2
chr17_+_27839974 1.335 ENSMUST00000071006.7
Snrpc
U1 small nuclear ribonucleoprotein C
chr9_+_47530173 1.312 ENSMUST00000114548.1
ENSMUST00000152459.1
ENSMUST00000143026.1
ENSMUST00000085909.2
ENSMUST00000114547.1
ENSMUST00000034581.3
Cadm1





cell adhesion molecule 1





chr7_+_28440927 1.277 ENSMUST00000078845.6
Gmfg
glia maturation factor, gamma
chr16_-_64771146 1.276 ENSMUST00000076991.6
4930453N24Rik
RIKEN cDNA 4930453N24 gene
chr18_-_34579072 1.273 ENSMUST00000079287.5
Nme5
NME/NM23 family member 5
chr1_+_74771886 1.253 ENSMUST00000006716.6
Wnt6
wingless-related MMTV integration site 6
chr12_+_8674224 1.252 ENSMUST00000111122.2
Pum2
pumilio 2 (Drosophila)
chr14_+_57798620 1.242 ENSMUST00000111268.1
Sap18
Sin3-associated polypeptide 18
chr8_+_22192800 1.240 ENSMUST00000033866.8
Vps36
vacuolar protein sorting 36 (yeast)
chr1_+_178319130 1.221 ENSMUST00000027781.6
Cox20
COX20 Cox2 chaperone
chr3_-_89279633 1.220 ENSMUST00000118860.1
ENSMUST00000029566.2
Efna1

ephrin A1

chr1_+_136624901 1.210 ENSMUST00000047734.8
ENSMUST00000112046.1
Zfp281

zinc finger protein 281

chr10_-_63023881 1.201 ENSMUST00000118898.1
ENSMUST00000020263.7
Hnrnph3

heterogeneous nuclear ribonucleoprotein H3

chr5_+_129941949 1.200 ENSMUST00000051758.7
ENSMUST00000073945.4
Vkorc1l1

vitamin K epoxide reductase complex, subunit 1-like 1

chr5_+_122158265 1.198 ENSMUST00000102528.4
ENSMUST00000086294.6
Ppp1cc

protein phosphatase 1, catalytic subunit, gamma isoform

chr7_+_51878967 1.186 ENSMUST00000051912.6
Gas2
growth arrest specific 2
chr19_-_44069526 1.179 ENSMUST00000170801.1
Erlin1
ER lipid raft associated 1
chr14_+_55672235 1.175 ENSMUST00000002397.5
Gmpr2
guanosine monophosphate reductase 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.2 37.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
3.6 10.9 GO:0072382 minus-end-directed vesicle transport along microtubule(GO:0072382)
2.9 8.6 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
2.1 10.3 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
2.0 36.1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
2.0 10.0 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
1.9 5.8 GO:0060282 positive regulation of oocyte development(GO:0060282)
1.6 11.3 GO:0000279 M phase(GO:0000279)
1.4 8.4 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
1.3 17.2 GO:0099628 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
1.3 7.9 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
1.3 7.5 GO:1901911 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
1.2 8.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
1.0 2.0 GO:0072717 cellular response to actinomycin D(GO:0072717)
1.0 8.0 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
1.0 11.8 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
1.0 16.3 GO:0030953 astral microtubule organization(GO:0030953)
0.9 4.7 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
0.9 3.7 GO:0051866 general adaptation syndrome(GO:0051866)
0.9 2.8 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.9 4.6 GO:0019659 fermentation(GO:0006113) lactate biosynthetic process from pyruvate(GO:0019244) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.8 1.7 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
0.8 5.9 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.8 5.8 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.8 13.2 GO:0070986 left/right axis specification(GO:0070986)
0.7 3.6 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.7 7.0 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.7 4.1 GO:0034587 piRNA metabolic process(GO:0034587)
0.6 5.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.6 3.8 GO:0006528 asparagine metabolic process(GO:0006528)
0.6 1.9 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) negative regulation of regulatory T cell differentiation(GO:0045590) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.6 2.3 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.6 8.9 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.5 6.9 GO:0019985 translesion synthesis(GO:0019985)
0.5 1.5 GO:1901536 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045869) regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536)
0.5 2.5 GO:0033762 response to glucagon(GO:0033762)
0.5 1.5 GO:1901420 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) negative regulation of response to alcohol(GO:1901420) positive regulation of macrophage apoptotic process(GO:2000111)
0.5 2.4 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.5 1.9 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.5 3.8 GO:0036159 inner dynein arm assembly(GO:0036159)
0.5 1.4 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.4 1.3 GO:0009826 unidimensional cell growth(GO:0009826) susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.4 2.2 GO:0032472 Golgi calcium ion transport(GO:0032472)
0.4 7.8 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.4 1.3 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.4 1.2 GO:0014028 notochord formation(GO:0014028)
0.4 2.0 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.4 1.2 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.4 2.8 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.4 8.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.4 1.1 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.4 1.1 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.3 2.1 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646) choline metabolic process(GO:0019695)
0.3 1.0 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.3 1.0 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.3 9.7 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.3 2.9 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.3 1.9 GO:0006172 ADP biosynthetic process(GO:0006172)
0.3 1.2 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.3 0.9 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241)
0.3 1.0 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.2 2.7 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.2 1.0 GO:0032053 ciliary basal body organization(GO:0032053)
0.2 8.0 GO:0007638 mechanosensory behavior(GO:0007638)
0.2 1.6 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.2 0.9 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.2 2.3 GO:1990173 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.2 1.1 GO:2001170 negative regulation of ATP biosynthetic process(GO:2001170)
0.2 4.0 GO:0090161 Golgi ribbon formation(GO:0090161)
0.2 1.8 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.2 1.4 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.2 1.2 GO:0009169 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.2 3.3 GO:0071539 protein localization to centrosome(GO:0071539)
0.2 4.1 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.2 1.2 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.2 5.5 GO:0034508 centromere complex assembly(GO:0034508)
0.2 1.4 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.2 1.7 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.2 0.8 GO:0002667 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) negative regulation of protein kinase C signaling(GO:0090038)
0.2 1.8 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.2 1.6 GO:0070475 rRNA base methylation(GO:0070475)
0.2 1.0 GO:1902965 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.2 2.6 GO:0046599 regulation of centriole replication(GO:0046599)
0.1 6.3 GO:0048255 mRNA stabilization(GO:0048255)
0.1 2.1 GO:0007099 centriole replication(GO:0007099)
0.1 1.2 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 7.2 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 2.3 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.1 2.5 GO:0034453 microtubule anchoring(GO:0034453)
0.1 2.8 GO:0045116 protein neddylation(GO:0045116)
0.1 0.9 GO:0002643 regulation of tolerance induction(GO:0002643)
0.1 1.3 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.1 1.0 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 1.9 GO:2001273 regulation of glucose import in response to insulin stimulus(GO:2001273)
0.1 0.6 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.1 0.8 GO:0043634 polyadenylation-dependent ncRNA catabolic process(GO:0043634)
0.1 1.1 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1 16.1 GO:0043484 regulation of RNA splicing(GO:0043484)
0.1 0.5 GO:0035617 stress granule disassembly(GO:0035617)
0.1 0.3 GO:0002014 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014)
0.1 0.9 GO:0002155 regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.1 3.5 GO:1902750 negative regulation of cell cycle G2/M phase transition(GO:1902750)
0.1 0.5 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 1.1 GO:0044380 protein localization to cytoskeleton(GO:0044380)
0.1 0.3 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.1 6.7 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.1 0.7 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.1 0.3 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.1 0.6 GO:0014029 neural crest formation(GO:0014029)
0.1 1.2 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 4.4 GO:0007127 meiosis I(GO:0007127)
0.1 1.0 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 0.5 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 1.1 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 0.7 GO:0022409 positive regulation of cell-cell adhesion(GO:0022409)
0.0 1.2 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.0 0.9 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.3 GO:0018377 N-terminal protein myristoylation(GO:0006499) protein myristoylation(GO:0018377)
0.0 0.9 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.0 0.3 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.0 1.0 GO:2000780 negative regulation of DNA repair(GO:0045738) negative regulation of double-strand break repair(GO:2000780)
0.0 0.4 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.4 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 1.4 GO:0034766 negative regulation of ion transmembrane transport(GO:0034766)
0.0 0.2 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.0 2.2 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.0 1.6 GO:0060325 face morphogenesis(GO:0060325)
0.0 1.2 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 3.1 GO:0008584 male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.0 3.3 GO:0048663 neuron fate commitment(GO:0048663)
0.0 0.3 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 3.0 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.7 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 2.0 GO:0000271 polysaccharide biosynthetic process(GO:0000271)
0.0 4.1 GO:0000082 G1/S transition of mitotic cell cycle(GO:0000082)
0.0 0.8 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 1.5 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.7 GO:0030252 growth hormone secretion(GO:0030252)
0.0 1.5 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.6 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 1.1 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 0.7 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.8 GO:0006970 response to osmotic stress(GO:0006970)
0.0 0.7 GO:0046324 regulation of glucose import(GO:0046324)
0.0 0.4 GO:0002437 inflammatory response to antigenic stimulus(GO:0002437)
0.0 0.1 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.0 1.5 GO:0030218 erythrocyte differentiation(GO:0030218)
0.0 0.3 GO:0006465 signal peptide processing(GO:0006465)
0.0 1.7 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.3 GO:0046686 response to cadmium ion(GO:0046686)
0.0 1.7 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 2.3 GO:0007018 microtubule-based movement(GO:0007018)
0.0 1.2 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.2 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.3 GO:0007030 Golgi organization(GO:0007030)
0.0 0.3 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 1.1 GO:0006364 rRNA processing(GO:0006364)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
5.9 17.8 GO:0099573 glutamatergic postsynaptic density(GO:0099573)
3.4 37.5 GO:0005642 annulate lamellae(GO:0005642)
2.2 6.7 GO:1990423 RZZ complex(GO:1990423)
2.1 8.6 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
1.9 5.8 GO:0042585 germinal vesicle(GO:0042585)
0.9 6.3 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.9 32.0 GO:0035371 microtubule plus-end(GO:0035371)
0.8 2.3 GO:1990047 spindle matrix(GO:1990047)
0.7 5.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.7 5.0 GO:0001940 male pronucleus(GO:0001940)
0.7 4.8 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.7 1.4 GO:0000799 nuclear condensin complex(GO:0000799)
0.6 4.5 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.6 1.9 GO:0035061 interchromatin granule(GO:0035061)
0.6 10.9 GO:0031616 spindle pole centrosome(GO:0031616)
0.6 2.4 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.6 4.1 GO:0001740 Barr body(GO:0001740)
0.6 3.3 GO:0035976 AP1 complex(GO:0035976)
0.5 2.0 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.5 4.5 GO:0061574 ASAP complex(GO:0061574)
0.5 1.5 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.5 1.4 GO:0005588 collagen type V trimer(GO:0005588)
0.4 10.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.4 1.2 GO:0000814 ESCRT II complex(GO:0000814)
0.4 0.4 GO:0099524 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.4 1.9 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.4 8.4 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.3 6.7 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.3 4.6 GO:0035686 sperm fibrous sheath(GO:0035686)
0.3 1.5 GO:0033553 rDNA heterochromatin(GO:0033553)
0.3 1.8 GO:0098536 deuterosome(GO:0098536)
0.3 0.9 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.3 4.1 GO:0031011 Ino80 complex(GO:0031011)
0.3 2.7 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2 2.4 GO:0000243 commitment complex(GO:0000243)
0.2 14.1 GO:0005882 intermediate filament(GO:0005882)
0.2 12.2 GO:0005871 kinesin complex(GO:0005871)
0.2 5.7 GO:0034451 centriolar satellite(GO:0034451)
0.2 3.0 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.2 1.0 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.2 2.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.2 5.2 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.2 10.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 1.8 GO:0045298 tubulin complex(GO:0045298)
0.2 15.9 GO:0005913 cell-cell adherens junction(GO:0005913)
0.2 1.1 GO:0005827 polar microtubule(GO:0005827)
0.1 0.9 GO:0071011 precatalytic spliceosome(GO:0071011)
0.1 0.8 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 11.3 GO:0000922 spindle pole(GO:0000922)
0.1 8.5 GO:0031519 PcG protein complex(GO:0031519)
0.1 8.5 GO:0005643 nuclear pore(GO:0005643)
0.1 1.8 GO:0000124 SAGA complex(GO:0000124)
0.1 0.8 GO:0072687 meiotic spindle(GO:0072687)
0.1 10.4 GO:0000776 kinetochore(GO:0000776)
0.1 1.0 GO:1990635 proximal dendrite(GO:1990635)
0.1 9.3 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 1.9 GO:0005839 proteasome core complex(GO:0005839)
0.1 8.2 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 7.2 GO:0005681 spliceosomal complex(GO:0005681)
0.1 2.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 4.7 GO:0005844 polysome(GO:0005844)
0.1 0.5 GO:0042405 nuclear inclusion body(GO:0042405)
0.1 1.1 GO:0005605 basal lamina(GO:0005605)
0.1 5.9 GO:0005901 caveola(GO:0005901)
0.0 17.1 GO:0005813 centrosome(GO:0005813)
0.0 1.0 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 1.5 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.3 GO:0005787 signal peptidase complex(GO:0005787)
0.0 4.0 GO:0022626 cytosolic ribosome(GO:0022626)
0.0 0.9 GO:0030686 90S preribosome(GO:0030686)
0.0 0.9 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 1.5 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 8.2 GO:0005925 focal adhesion(GO:0005925)
0.0 0.7 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.6 GO:0016235 aggresome(GO:0016235)
0.0 0.6 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 0.5 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) small ribosomal subunit(GO:0015935)
0.0 13.3 GO:0005730 nucleolus(GO:0005730)
0.0 2.8 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 1.0 GO:0000502 proteasome complex(GO:0000502)
0.0 2.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.9 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.0 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.5 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 0.1 GO:0005922 connexon complex(GO:0005922)
0.0 1.0 GO:1990204 oxidoreductase complex(GO:1990204)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 10.3 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
2.3 37.1 GO:0017070 U6 snRNA binding(GO:0017070)
1.9 11.3 GO:0010997 anaphase-promoting complex binding(GO:0010997)
1.7 5.1 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
1.7 6.7 GO:0097100 supercoiled DNA binding(GO:0097100)
1.5 17.8 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
1.3 5.0 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
1.3 7.5 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
1.2 5.8 GO:0035174 histone serine kinase activity(GO:0035174)
1.1 4.6 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
1.0 5.9 GO:0008494 translation activator activity(GO:0008494)
0.8 3.2 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.6 8.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.6 8.8 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.5 3.8 GO:0008242 omega peptidase activity(GO:0008242)
0.5 2.1 GO:0004104 choline kinase activity(GO:0004103) cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.5 1.5 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.5 1.9 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.4 3.6 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.4 7.0 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.4 1.5 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.4 7.9 GO:0070410 co-SMAD binding(GO:0070410)
0.4 2.9 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.4 5.0 GO:1990226 histone methyltransferase binding(GO:1990226)
0.3 2.0 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.3 10.5 GO:0017025 TBP-class protein binding(GO:0017025)
0.3 8.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.3 2.4 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.3 2.4 GO:1990446 U1 snRNP binding(GO:1990446)
0.2 4.7 GO:0035497 cAMP response element binding(GO:0035497)
0.2 3.0 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.2 1.6 GO:0032564 dATP binding(GO:0032564)
0.2 5.8 GO:0070064 proline-rich region binding(GO:0070064)
0.2 1.0 GO:0004849 uridine kinase activity(GO:0004849)
0.2 0.8 GO:0003998 acylphosphatase activity(GO:0003998)
0.2 6.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.2 1.0 GO:0070878 primary miRNA binding(GO:0070878)
0.2 1.1 GO:0043141 TFIID-class transcription factor binding(GO:0001094) ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.2 8.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.2 1.9 GO:0004017 adenylate kinase activity(GO:0004017)
0.2 12.2 GO:0003777 microtubule motor activity(GO:0003777)
0.2 0.9 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 10.9 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.1 1.7 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 5.6 GO:0045182 translation regulator activity(GO:0045182)
0.1 1.5 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 6.0 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 7.9 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 1.8 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.1 0.8 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 1.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 3.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 1.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 1.1 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.1 1.3 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 1.2 GO:0031386 protein tag(GO:0031386)
0.1 1.8 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 4.1 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 1.9 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 1.2 GO:0048038 quinone binding(GO:0048038)
0.1 0.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578) Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.9 GO:0031996 thioesterase binding(GO:0031996)
0.1 0.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.1 2.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 4.0 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 0.9 GO:0008143 poly(A) binding(GO:0008143)
0.1 1.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.4 GO:0070739 NEDD8 transferase activity(GO:0019788) protein-glutamic acid ligase activity(GO:0070739)
0.1 1.9 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 1.8 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 3.1 GO:0005179 hormone activity(GO:0005179)
0.0 0.8 GO:0051861 glycolipid binding(GO:0051861)
0.0 1.9 GO:0005109 frizzled binding(GO:0005109)
0.0 1.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.7 GO:0015149 hexose transmembrane transporter activity(GO:0015149)
0.0 1.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.0 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 1.7 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 1.0 GO:0031491 nucleosome binding(GO:0031491)
0.0 1.7 GO:0030332 cyclin binding(GO:0030332)
0.0 0.9 GO:0043274 phospholipase binding(GO:0043274)
0.0 6.2 GO:0042393 histone binding(GO:0042393)
0.0 0.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 3.0 GO:0004386 helicase activity(GO:0004386)
0.0 0.8 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 2.5 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.7 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.7 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 8.4 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 1.6 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 0.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 2.7 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 1.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.7 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.3 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 1.2 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.2 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0005243 gap junction channel activity(GO:0005243)
0.0 2.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.7 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.1 GO:0030275 LRR domain binding(GO:0030275)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 17.8 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.6 40.2 PID_PLK1_PATHWAY PLK1 signaling events
0.5 17.0 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.4 27.8 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.3 8.6 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2 16.6 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.2 2.8 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.1 4.3 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.1 7.9 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 3.0 PID_ATM_PATHWAY ATM pathway
0.1 3.6 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.1 1.2 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 2.4 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.1 1.5 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.1 1.2 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.1 5.0 PID_AVB3_INTEGRIN_PATHWAY Integrins in angiogenesis
0.1 4.6 PID_CMYB_PATHWAY C-MYB transcription factor network
0.1 2.4 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.1 4.0 PID_P53_REGULATION_PATHWAY p53 pathway
0.1 0.5 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.1 0.9 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.1 0.9 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.1 4.8 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 2.1 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 1.1 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.6 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.0 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 1.0 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 0.3 PID_BCR_5PATHWAY BCR signaling pathway
0.0 0.5 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 1.3 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 2.1 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.6 PID_LKB1_PATHWAY LKB1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 37.1 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.8 6.7 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.7 17.3 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.7 18.7 REACTOME_KINESINS Genes involved in Kinesins
0.6 15.0 REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.5 18.3 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.4 5.1 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.4 39.4 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.3 10.2 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.3 10.0 REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Activation of the pre-replicative complex
0.2 7.9 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2 4.6 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism
0.2 5.4 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.2 1.0 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.2 4.2 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.2 2.1 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.2 9.1 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.2 2.7 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 9.3 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 7.7 REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1 7.7 REACTOME_AMYLOIDS Genes involved in Amyloids
0.1 4.4 REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.1 11.4 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.1 0.9 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.1 0.5 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.1 2.2 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 2.4 REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.1 1.9 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.2 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.1 0.8 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.1 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.1 3.7 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.2 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 0.5 REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS Genes involved in Activation of ATR in response to replication stress
0.0 1.0 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.0 1.2 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.5 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 1.3 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 3.0 REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 2.2 REACTOME_GENERIC_TRANSCRIPTION_PATHWAY Genes involved in Generic Transcription Pathway
0.0 1.4 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.6 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME_ACYL_CHAIN_REMODELLING_OF_PC Genes involved in Acyl chain remodelling of PC
0.0 1.7 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.1 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 2.0 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 0.7 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.3 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.3 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.1 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 0.7 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors