Motif ID: Pitx1

Z-value: 0.613


Transcription factors associated with Pitx1:

Gene SymbolEntrez IDGene Name
Pitx1 ENSMUSG00000021506.7 Pitx1



Activity profile for motif Pitx1.

activity profile for motif Pitx1


Sorted Z-values histogram for motif Pitx1

Sorted Z-values for motif Pitx1



Network of associatons between targets according to the STRING database.



First level regulatory network of Pitx1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_+_18818895 1.961 ENSMUST00000166873.2
Cdh10
cadherin 10
chr13_-_97747399 1.951 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr4_+_144892813 1.908 ENSMUST00000105744.1
ENSMUST00000171001.1
Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr4_+_144893077 1.701 ENSMUST00000154208.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr7_-_15879844 1.585 ENSMUST00000172758.1
ENSMUST00000044434.6
Crx

cone-rod homeobox containing gene

chr2_+_102658640 1.565 ENSMUST00000080210.3
Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr4_+_144893127 1.548 ENSMUST00000142808.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr3_-_84270782 1.540 ENSMUST00000054990.4
Trim2
tripartite motif-containing 2
chr1_-_155232710 1.459 ENSMUST00000035914.3
BC034090
cDNA sequence BC034090
chr6_+_4902913 1.414 ENSMUST00000175889.1
ENSMUST00000168998.2
Ppp1r9a

protein phosphatase 1, regulatory (inhibitor) subunit 9A

chr7_-_80403315 1.404 ENSMUST00000147150.1
Furin
furin (paired basic amino acid cleaving enzyme)
chr14_+_64588112 1.269 ENSMUST00000181808.1
A930011O12Rik
RIKEN cDNA A930011O12 gene
chr16_-_46010212 1.193 ENSMUST00000130481.1
Plcxd2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr5_+_3343893 1.099 ENSMUST00000165117.1
Cdk6
cyclin-dependent kinase 6
chr3_+_89520152 1.085 ENSMUST00000000811.7
Kcnn3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr2_+_119325784 1.069 ENSMUST00000102517.3
Dll4
delta-like 4 (Drosophila)
chrX_+_169879596 1.068 ENSMUST00000112105.1
ENSMUST00000078947.5
Mid1

midline 1

chr10_+_69925484 1.056 ENSMUST00000182692.1
ENSMUST00000092433.5
Ank3

ankyrin 3, epithelial

chr6_+_4903350 1.034 ENSMUST00000175962.1
Ppp1r9a
protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr1_-_165934900 1.033 ENSMUST00000069609.5
ENSMUST00000111427.2
ENSMUST00000111426.4
Pou2f1


POU domain, class 2, transcription factor 1


chr10_+_69925766 0.999 ENSMUST00000182269.1
ENSMUST00000183261.1
ENSMUST00000183074.1
Ank3


ankyrin 3, epithelial


chr4_+_99829437 0.992 ENSMUST00000124547.1
ENSMUST00000106994.1
Efcab7

EF-hand calcium binding domain 7

chr9_-_54501496 0.987 ENSMUST00000118600.1
ENSMUST00000118163.1
Dmxl2

Dmx-like 2

chr13_-_97747373 0.980 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr10_+_69925800 0.967 ENSMUST00000182029.1
Ank3
ankyrin 3, epithelial
chr10_+_69925954 0.965 ENSMUST00000181974.1
ENSMUST00000182795.1
ENSMUST00000182437.1
Ank3


ankyrin 3, epithelial


chr11_-_100472725 0.950 ENSMUST00000056665.3
Klhl11
kelch-like 11
chr1_-_170110491 0.946 ENSMUST00000027985.2
Ddr2
discoidin domain receptor family, member 2
chr15_+_4375462 0.924 ENSMUST00000061925.4
Plcxd3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr7_-_127725616 0.920 ENSMUST00000076091.2
Ctf2
cardiotrophin 2
chr11_+_70459940 0.919 ENSMUST00000147289.1
ENSMUST00000126105.1
Zmynd15

zinc finger, MYND-type containing 15

chr4_-_155010984 0.887 ENSMUST00000105631.2
ENSMUST00000139976.2
ENSMUST00000145662.2
Plch2


phospholipase C, eta 2


chr18_-_15718046 0.885 ENSMUST00000053017.6
Chst9
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr6_+_108213086 0.853 ENSMUST00000032192.6
Itpr1
inositol 1,4,5-trisphosphate receptor 1
chr5_+_3344194 0.845 ENSMUST00000042410.4
Cdk6
cyclin-dependent kinase 6
chr9_+_32224457 0.819 ENSMUST00000183121.1
Arhgap32
Rho GTPase activating protein 32
chr8_-_11678728 0.784 ENSMUST00000033906.4
1700016D06Rik
RIKEN cDNA 1700016D06 gene
chrX_+_169685191 0.775 ENSMUST00000112104.1
ENSMUST00000112107.1
Mid1

midline 1

chr7_-_98656530 0.757 ENSMUST00000038359.4
2210018M11Rik
RIKEN cDNA 2210018M11 gene
chr6_+_4903298 0.748 ENSMUST00000035813.2
Ppp1r9a
protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr9_+_58134535 0.745 ENSMUST00000128378.1
ENSMUST00000150820.1
ENSMUST00000167479.1
ENSMUST00000134450.1
Stra6



stimulated by retinoic acid gene 6



chr1_+_66322102 0.738 ENSMUST00000123647.1
Map2
microtubule-associated protein 2
chr5_-_134456702 0.723 ENSMUST00000073161.5
ENSMUST00000171794.2
ENSMUST00000111245.2
ENSMUST00000100654.3
ENSMUST00000167084.2
ENSMUST00000100652.3
ENSMUST00000100650.3
ENSMUST00000074114.5
Gtf2ird1







general transcription factor II I repeat domain-containing 1







chr6_-_93913678 0.711 ENSMUST00000093769.5
Magi1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr18_+_36281069 0.704 ENSMUST00000051301.3
Pura
purine rich element binding protein A
chr14_+_26122609 0.698 ENSMUST00000100810.6
Duxbl2
doubl homeobox B-like 2
chr10_+_18407658 0.694 ENSMUST00000037341.7
Nhsl1
NHS-like 1
chr10_+_4266323 0.692 ENSMUST00000045730.5
Akap12
A kinase (PRKA) anchor protein (gravin) 12
chr6_+_3993776 0.680 ENSMUST00000031673.5
Gngt1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr9_+_32224246 0.661 ENSMUST00000168954.2
Arhgap32
Rho GTPase activating protein 32
chr14_+_25983005 0.650 ENSMUST00000049793.8
Duxbl1
double homeobox B-like 1
chr4_-_52497244 0.650 ENSMUST00000114578.4
Vma21-ps
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae), pseudogene
chr4_-_140246751 0.647 ENSMUST00000039331.8
Igsf21
immunoglobulin superfamily, member 21
chr16_-_91011093 0.643 ENSMUST00000170853.1
ENSMUST00000118390.2
Synj1

synaptojanin 1

chr11_+_3330781 0.620 ENSMUST00000136536.1
ENSMUST00000093399.4
Pik3ip1

phosphoinositide-3-kinase interacting protein 1

chr8_-_111259192 0.617 ENSMUST00000169020.1
ENSMUST00000003404.8
Glg1

golgi apparatus protein 1

chr1_+_66321708 0.608 ENSMUST00000114013.1
Map2
microtubule-associated protein 2
chr11_-_51756378 0.606 ENSMUST00000109092.1
ENSMUST00000064297.4
ENSMUST00000109097.2
Sec24a


Sec24 related gene family, member A (S. cerevisiae)


chr2_+_69670100 0.599 ENSMUST00000100050.3
Klhl41
kelch-like 41
chr16_-_91011029 0.594 ENSMUST00000130813.1
Synj1
synaptojanin 1
chr11_+_23256566 0.585 ENSMUST00000136235.1
Xpo1
exportin 1, CRM1 homolog (yeast)
chr2_+_28506095 0.584 ENSMUST00000074761.4
Gm10134
predicted gene 10134
chr9_-_50617228 0.581 ENSMUST00000147671.1
ENSMUST00000145139.1
ENSMUST00000155435.1
AU019823


expressed sequence AU019823


chr1_+_179961110 0.572 ENSMUST00000076687.5
ENSMUST00000097450.3
Cdc42bpa

CDC42 binding protein kinase alpha

chr13_+_113035111 0.553 ENSMUST00000180543.1
ENSMUST00000181568.1
ENSMUST00000109244.2
ENSMUST00000181117.1
ENSMUST00000181741.1
Cdc20b




cell division cycle 20B




chr1_-_173367638 0.543 ENSMUST00000005470.4
ENSMUST00000111220.1
Cadm3

cell adhesion molecule 3

chr10_+_19951055 0.539 ENSMUST00000152533.1
Map3k5
mitogen-activated protein kinase kinase kinase 5
chr10_-_127288851 0.527 ENSMUST00000156208.1
ENSMUST00000026476.6
Mbd6

methyl-CpG binding domain protein 6

chr5_-_36695969 0.519 ENSMUST00000031091.9
ENSMUST00000140063.1
D5Ertd579e

DNA segment, Chr 5, ERATO Doi 579, expressed

chr2_-_18048784 0.516 ENSMUST00000142856.1
Skida1
SKI/DACH domain containing 1
chr5_+_8422908 0.516 ENSMUST00000170496.1
Slc25a40
solute carrier family 25, member 40
chr6_+_136954521 0.500 ENSMUST00000137768.1
Pde6h
phosphodiesterase 6H, cGMP-specific, cone, gamma
chr1_-_51915968 0.499 ENSMUST00000046390.7
Myo1b
myosin IB
chr4_-_64046925 0.483 ENSMUST00000107377.3
Tnc
tenascin C
chr17_+_75005523 0.480 ENSMUST00000001927.5
Ltbp1
latent transforming growth factor beta binding protein 1
chr16_+_11405648 0.470 ENSMUST00000096273.2
Snx29
sorting nexin 29
chrX_+_7909542 0.465 ENSMUST00000086274.2
Gm10490
predicted gene 10490
chr3_-_113630068 0.462 ENSMUST00000092154.3
ENSMUST00000106536.1
ENSMUST00000106535.1
Rnpc3


RNA-binding region (RNP1, RRM) containing 3


chr6_-_122340200 0.444 ENSMUST00000159384.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr3_+_105973711 0.442 ENSMUST00000000573.2
Ovgp1
oviductal glycoprotein 1
chr1_-_44218952 0.441 ENSMUST00000054801.3
Mettl21e
methyltransferase like 21E
chr5_-_92435219 0.441 ENSMUST00000038514.8
Nup54
nucleoporin 54
chr6_+_121300227 0.439 ENSMUST00000064580.7
Slc6a13
solute carrier family 6 (neurotransmitter transporter, GABA), member 13
chr10_-_127288999 0.426 ENSMUST00000119078.1
Mbd6
methyl-CpG binding domain protein 6
chr6_-_35308110 0.422 ENSMUST00000031868.4
Slc13a4
solute carrier family 13 (sodium/sulfate symporters), member 4
chr1_+_157458554 0.422 ENSMUST00000046743.4
ENSMUST00000119891.1
BC026585

cDNA sequence BC026585

chr8_+_20136455 0.421 ENSMUST00000179299.1
ENSMUST00000096485.4
Gm21811

predicted gene, 21811

chr15_+_36179530 0.418 ENSMUST00000171205.1
Spag1
sperm associated antigen 1
chr5_+_8422831 0.418 ENSMUST00000066921.3
Slc25a40
solute carrier family 25, member 40
chr11_+_116657106 0.412 ENSMUST00000116318.2
Gm11744
predicted gene 11744
chr4_-_42661893 0.411 ENSMUST00000108006.3
Il11ra2
interleukin 11 receptor, alpha chain 2
chr2_+_125068118 0.403 ENSMUST00000070353.3
Slc24a5
solute carrier family 24, member 5
chr1_-_158958367 0.398 ENSMUST00000159861.2
Pappa2
pappalysin 2
chr14_+_99298652 0.396 ENSMUST00000005279.6
Klf5
Kruppel-like factor 5
chr6_+_17749170 0.394 ENSMUST00000053148.7
ENSMUST00000115417.3
St7

suppression of tumorigenicity 7

chr7_-_133123770 0.391 ENSMUST00000164896.1
ENSMUST00000171968.1
Ctbp2

C-terminal binding protein 2

chr10_-_22149270 0.389 ENSMUST00000179054.1
ENSMUST00000069372.6
E030030I06Rik

RIKEN cDNA E030030I06 gene

chr9_+_50617516 0.384 ENSMUST00000141366.1
Pih1d2
PIH1 domain containing 2
chr7_+_101969796 0.379 ENSMUST00000084852.5
Numa1
nuclear mitotic apparatus protein 1
chr11_-_29247208 0.374 ENSMUST00000020754.3
Ccdc104
coiled-coil domain containing 104
chr11_+_19924403 0.357 ENSMUST00000093298.5
Spred2
sprouty-related, EVH1 domain containing 2
chr18_+_37320374 0.344 ENSMUST00000078271.2
Pcdhb5
protocadherin beta 5
chr9_-_50617428 0.329 ENSMUST00000131351.1
ENSMUST00000171462.1
AU019823

expressed sequence AU019823

chr14_-_54926784 0.327 ENSMUST00000022813.6
Efs
embryonal Fyn-associated substrate
chr9_+_31030621 0.327 ENSMUST00000115222.2
Zbtb44
zinc finger and BTB domain containing 44
chr1_-_191907527 0.327 ENSMUST00000069573.5
1700034H15Rik
RIKEN cDNA 1700034H15 gene
chr2_+_38341068 0.325 ENSMUST00000133661.1
Lhx2
LIM homeobox protein 2
chr19_+_8617991 0.325 ENSMUST00000010250.2
Slc22a6
solute carrier family 22 (organic anion transporter), member 6
chr2_+_23068168 0.323 ENSMUST00000028121.7
ENSMUST00000114523.2
ENSMUST00000144088.1
Acbd5


acyl-Coenzyme A binding domain containing 5


chr16_-_34095983 0.318 ENSMUST00000114973.1
ENSMUST00000114964.1
Kalrn

kalirin, RhoGEF kinase

chr8_+_78509319 0.317 ENSMUST00000034111.8
Slc10a7
solute carrier family 10 (sodium/bile acid cotransporter family), member 7
chr10_-_92165159 0.316 ENSMUST00000182567.1
ENSMUST00000181604.2
ENSMUST00000181213.1
Rmst


rhabdomyosarcoma 2 associated transcript (non-coding RNA)


chr1_+_87403705 0.306 ENSMUST00000172736.1
Gigyf2
GRB10 interacting GYF protein 2
chr10_-_117376922 0.290 ENSMUST00000177145.1
ENSMUST00000176670.1
Cpsf6

cleavage and polyadenylation specific factor 6

chr16_-_31081363 0.285 ENSMUST00000055389.7
Xxylt1
xyloside xylosyltransferase 1
chr3_+_95526777 0.285 ENSMUST00000015667.2
ENSMUST00000116304.2
Ctss

cathepsin S

chr3_+_88616133 0.281 ENSMUST00000176500.1
ENSMUST00000177498.1
Arhgef2

rho/rac guanine nucleotide exchange factor (GEF) 2

chr2_-_167060417 0.275 ENSMUST00000155281.1
Znfx1
zinc finger, NFX1-type containing 1
chr19_-_47919269 0.271 ENSMUST00000095998.5
Itprip
inositol 1,4,5-triphosphate receptor interacting protein
chr5_-_5694559 0.269 ENSMUST00000115426.2
Steap2
six transmembrane epithelial antigen of prostate 2
chr18_+_37447641 0.268 ENSMUST00000052387.3
Pcdhb14
protocadherin beta 14
chr10_-_117376955 0.268 ENSMUST00000069168.6
ENSMUST00000176686.1
Cpsf6

cleavage and polyadenylation specific factor 6

chr4_+_116708687 0.268 ENSMUST00000135499.1
Ccdc163
coiled-coil domain containing 163
chr11_+_23256001 0.262 ENSMUST00000020538.6
ENSMUST00000109551.1
ENSMUST00000102870.1
ENSMUST00000102869.1
Xpo1



exportin 1, CRM1 homolog (yeast)



chr13_+_3361029 0.261 ENSMUST00000179981.1
Gm16505
predicted gene 16505
chr19_-_32196393 0.257 ENSMUST00000151822.1
Sgms1
sphingomyelin synthase 1
chr11_-_106920359 0.254 ENSMUST00000167787.1
ENSMUST00000092517.2
Smurf2

SMAD specific E3 ubiquitin protein ligase 2

chr10_-_9901079 0.245 ENSMUST00000141722.1
Stxbp5
syntaxin binding protein 5 (tomosyn)
chr17_+_35089229 0.240 ENSMUST00000007251.7
Abhd16a
abhydrolase domain containing 16A
chr1_-_119648903 0.239 ENSMUST00000163147.1
ENSMUST00000052404.6
ENSMUST00000027632.7
Epb4.1l5


erythrocyte protein band 4.1-like 5


chr5_+_64159429 0.239 ENSMUST00000043893.6
Tbc1d1
TBC1 domain family, member 1
chr2_-_18048347 0.235 ENSMUST00000066885.5
Skida1
SKI/DACH domain containing 1
chrX_+_74424534 0.234 ENSMUST00000135165.1
ENSMUST00000114128.1
ENSMUST00000114133.2
ENSMUST00000004330.3
Ikbkg



inhibitor of kappaB kinase gamma



chr8_+_19682268 0.231 ENSMUST00000153710.1
ENSMUST00000127799.1
Gm6483

predicted gene 6483

chr3_+_28781305 0.229 ENSMUST00000060500.7
Eif5a2
eukaryotic translation initiation factor 5A2
chr7_-_25398697 0.228 ENSMUST00000105177.2
ENSMUST00000149349.1
Lipe

lipase, hormone sensitive

chr6_+_29361410 0.223 ENSMUST00000156163.1
Calu
calumenin
chr7_+_35802593 0.222 ENSMUST00000052454.2
E130304I02Rik
RIKEN cDNA E130304I02 gene
chr11_+_87578384 0.221 ENSMUST00000107962.1
ENSMUST00000122067.1
Sept4

septin 4

chr18_+_73863672 0.215 ENSMUST00000134847.1
Mro
maestro
chrX_+_74424632 0.211 ENSMUST00000114129.2
ENSMUST00000132749.1
Ikbkg

inhibitor of kappaB kinase gamma

chr5_-_23616528 0.210 ENSMUST00000088392.4
Srpk2
serine/arginine-rich protein specific kinase 2
chr14_-_31640878 0.208 ENSMUST00000167066.1
ENSMUST00000127204.2
ENSMUST00000022437.8
Hacl1


2-hydroxyacyl-CoA lyase 1


chr18_-_25753852 0.205 ENSMUST00000025117.6
ENSMUST00000115816.2
Celf4

CUGBP, Elav-like family member 4

chr17_+_56770258 0.204 ENSMUST00000168666.2
Prr22
proline rich 22
chr17_-_85090204 0.202 ENSMUST00000072406.3
ENSMUST00000171795.1
Prepl

prolyl endopeptidase-like

chr2_-_23040137 0.202 ENSMUST00000091394.6
ENSMUST00000093171.6
Abi1

abl-interactor 1

chr2_-_23040177 0.201 ENSMUST00000114544.3
ENSMUST00000139038.1
ENSMUST00000126112.1
ENSMUST00000178908.1
ENSMUST00000078977.7
ENSMUST00000140164.1
ENSMUST00000149719.1
Abi1






abl-interactor 1






chr9_+_107340593 0.200 ENSMUST00000042581.2
6430571L13Rik
RIKEN cDNA 6430571L13 gene
chr1_+_99772765 0.193 ENSMUST00000086738.3
Cntnap5b
contactin associated protein-like 5B
chr10_-_14718191 0.193 ENSMUST00000020016.4
Gje1
gap junction protein, epsilon 1
chr1_-_13372434 0.192 ENSMUST00000081713.4
Ncoa2
nuclear receptor coactivator 2
chrX_+_82948861 0.190 ENSMUST00000114000.1
Dmd
dystrophin, muscular dystrophy
chr19_-_32712287 0.189 ENSMUST00000070210.4
Atad1
ATPase family, AAA domain containing 1
chr8_+_127063893 0.188 ENSMUST00000162309.1
Pard3
par-3 (partitioning defective 3) homolog (C. elegans)
chr10_+_90576872 0.186 ENSMUST00000182550.1
ENSMUST00000099364.5
Anks1b

ankyrin repeat and sterile alpha motif domain containing 1B

chr12_-_79192248 0.180 ENSMUST00000161204.1
Rdh11
retinol dehydrogenase 11
chr1_+_178187721 0.173 ENSMUST00000159284.1
Desi2
desumoylating isopeptidase 2
chr13_-_113618549 0.172 ENSMUST00000109241.3
Snx18
sorting nexin 18
chr6_+_122707489 0.170 ENSMUST00000112581.1
ENSMUST00000112580.1
ENSMUST00000012540.4
Nanog


Nanog homeobox


chr15_-_81190720 0.170 ENSMUST00000131235.1
ENSMUST00000134469.1
ENSMUST00000149582.1
Mkl1


MKL (megakaryoblastic leukemia)/myocardin-like 1


chr2_+_136892168 0.164 ENSMUST00000099311.2
Slx4ip
SLX4 interacting protein
chr3_-_57294880 0.163 ENSMUST00000171384.1
Tm4sf1
transmembrane 4 superfamily member 1
chr4_+_84884366 0.161 ENSMUST00000102819.3
Cntln
centlein, centrosomal protein
chr10_-_127189981 0.155 ENSMUST00000019611.7
Arhgef25
Rho guanine nucleotide exchange factor (GEF) 25
chr5_+_137641334 0.153 ENSMUST00000177466.1
ENSMUST00000166099.2
Sap25

sin3 associated polypeptide

chr11_+_115900125 0.146 ENSMUST00000142089.1
ENSMUST00000131566.1
Smim5

small integral membrane protein 5

chr1_+_74542881 0.139 ENSMUST00000113749.1
ENSMUST00000067916.6
ENSMUST00000113745.1
ENSMUST00000113747.1
ENSMUST00000113750.1
Plcd4




phospholipase C, delta 4




chr3_+_55782500 0.135 ENSMUST00000075422.4
Mab21l1
mab-21-like 1 (C. elegans)
chr11_-_70459957 0.129 ENSMUST00000019064.2
Cxcl16
chemokine (C-X-C motif) ligand 16
chr10_+_80329953 0.129 ENSMUST00000105358.1
ENSMUST00000105357.1
ENSMUST00000105354.1
ENSMUST00000105355.1
Reep6



receptor accessory protein 6



chr4_+_84884418 0.125 ENSMUST00000169371.2
Cntln
centlein, centrosomal protein
chr11_+_95010277 0.114 ENSMUST00000124735.1
Samd14
sterile alpha motif domain containing 14
chr13_+_63014934 0.109 ENSMUST00000091560.4
2010111I01Rik
RIKEN cDNA 2010111I01 gene
chr16_-_15594472 0.098 ENSMUST00000118236.1
ENSMUST00000096234.3
Ube2v2

ubiquitin-conjugating enzyme E2 variant 2

chr8_+_127064022 0.097 ENSMUST00000160272.1
ENSMUST00000079777.5
ENSMUST00000162907.1
Pard3


par-3 (partitioning defective 3) homolog (C. elegans)


chr3_+_103809520 0.097 ENSMUST00000076599.1
ENSMUST00000106824.1
ENSMUST00000106823.1
ENSMUST00000047285.2
Ap4b1



adaptor-related protein complex AP-4, beta 1



chr5_+_137787769 0.094 ENSMUST00000035852.7
Zcwpw1
zinc finger, CW type with PWWP domain 1
chr11_-_107337556 0.091 ENSMUST00000040380.6
Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chr10_+_21993890 0.082 ENSMUST00000092673.4
Sgk1
serum/glucocorticoid regulated kinase 1
chr7_-_134232005 0.080 ENSMUST00000134504.1
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr17_+_7925990 0.068 ENSMUST00000036370.7
Tagap
T cell activation Rho GTPase activating protein
chr17_+_34969912 0.064 ENSMUST00000173680.1
Gm20481
predicted gene 20481
chr12_+_81631369 0.063 ENSMUST00000036116.5
Ttc9
tetratricopeptide repeat domain 9
chr12_-_102439813 0.057 ENSMUST00000021607.8
Lgmn
legumain
chr9_-_110101010 0.050 ENSMUST00000062368.6
Dhx30
DEAH (Asp-Glu-Ala-His) box polypeptide 30
chr5_+_149184678 0.046 ENSMUST00000139474.1
ENSMUST00000117878.1
Uspl1

ubiquitin specific peptidase like 1

chr6_-_59426279 0.045 ENSMUST00000051065.4
Gprin3
GPRIN family member 3
chr14_+_59201418 0.040 ENSMUST00000140136.2
ENSMUST00000142326.1
Rcbtb1

regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1

chr1_-_168431896 0.039 ENSMUST00000176540.1
Pbx1
pre B cell leukemia homeobox 1
chr6_+_58833689 0.037 ENSMUST00000041401.8
Herc3
hect domain and RLD 3
chr3_-_33083016 0.035 ENSMUST00000078226.3
ENSMUST00000108224.1
Pex5l

peroxisomal biogenesis factor 5-like

chr12_+_58211772 0.030 ENSMUST00000110671.2
ENSMUST00000044299.2
Sstr1

somatostatin receptor 1

chrX_+_93675088 0.025 ENSMUST00000045898.3
Pcyt1b
phosphate cytidylyltransferase 1, choline, beta isoform
chr12_+_8921598 0.004 ENSMUST00000020909.3
Laptm4a
lysosomal-associated protein transmembrane 4A
chr9_+_44101722 0.002 ENSMUST00000161703.1
ENSMUST00000161381.1
ENSMUST00000034654.7
Mfrp


membrane-type frizzled-related protein



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.5 5.2 GO:0042572 retinol metabolic process(GO:0042572)
0.4 1.2 GO:1904978 regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980)
0.4 4.0 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.4 1.1 GO:0072554 blood vessel lumenization(GO:0072554) negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.4 1.4 GO:0090472 dibasic protein processing(GO:0090472)
0.3 1.9 GO:0044838 cell quiescence(GO:0044838)
0.3 0.8 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.2 1.6 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.2 1.8 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.7 GO:0046864 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865) alveolar primary septum development(GO:0061143)
0.1 1.0 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 0.4 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.4 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.1 0.7 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 0.9 GO:0042045 epithelial fluid transport(GO:0042045)
0.1 0.6 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 0.9 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 1.0 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.3 GO:0015747 urate transport(GO:0015747)
0.1 0.4 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1 0.5 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.1 0.4 GO:1904778 regulation of metaphase plate congression(GO:0090235) regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 0.6 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.7 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.2 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.1 0.2 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.7 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.7 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.4 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 0.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 0.9 GO:0007602 phototransduction(GO:0007602)
0.1 0.2 GO:1903225 regulation of endodermal cell fate specification(GO:0042663) negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.3 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 0.3 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.4 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.3 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.3 GO:0003383 apical constriction(GO:0003383)
0.0 0.3 GO:0030242 pexophagy(GO:0030242)
0.0 0.4 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.0 0.2 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.2 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 1.6 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.3 GO:0061368 maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.5 GO:1902170 cellular response to reactive nitrogen species(GO:1902170)
0.0 0.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.1 GO:0042275 error-free postreplication DNA repair(GO:0042275)
0.0 0.4 GO:0008272 sulfate transport(GO:0008272)
0.0 2.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.2 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.3 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.2 GO:1904017 positive regulation of female receptivity(GO:0045925) response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0 0.2 GO:0036089 cleavage furrow formation(GO:0036089)
0.0 0.3 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.2 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.3 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.6 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.4 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.5 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.0 0.5 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 0.6 GO:0010955 negative regulation of protein processing(GO:0010955) negative regulation of protein maturation(GO:1903318)
0.0 0.1 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.3 GO:2000678 negative regulation of transcription regulatory region DNA binding(GO:2000678)
0.0 0.2 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.3 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.0 0.1 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.6 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 0.0 GO:0030576 Cajal body organization(GO:0030576)
0.0 2.7 GO:0016042 lipid catabolic process(GO:0016042)
0.0 1.8 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.2 GO:1990761 growth cone lamellipodium(GO:1990761)
0.3 0.9 GO:0031088 platelet dense granule membrane(GO:0031088)
0.2 0.5 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.2 4.0 GO:0033270 paranode region of axon(GO:0033270)
0.1 1.3 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.5 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.4 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 1.4 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 0.8 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.4 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 0.6 GO:0042382 paraspeckles(GO:0042382)
0.0 1.0 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 0.7 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.4 GO:0001739 sex chromatin(GO:0001739)
0.0 1.0 GO:0010369 chromocenter(GO:0010369)
0.0 0.3 GO:0033269 internode region of axon(GO:0033269)
0.0 0.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 1.6 GO:0030673 axolemma(GO:0030673)
0.0 0.6 GO:0031143 pseudopodium(GO:0031143)
0.0 2.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.6 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 1.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.3 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.3 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.2 GO:0097227 sperm annulus(GO:0097227)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 1.0 GO:0008021 synaptic vesicle(GO:0008021)
0.0 1.8 GO:0030175 filopodium(GO:0030175)
0.0 0.3 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)
0.0 1.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.4 GO:0001917 photoreceptor inner segment(GO:0001917)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 5.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.6 1.9 GO:0098770 FBXO family protein binding(GO:0098770)
0.3 0.9 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.3 1.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.3 0.8 GO:0003796 lysozyme activity(GO:0003796)
0.3 1.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.2 1.2 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.2 0.9 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.2 0.6 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.2 0.7 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 1.3 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 0.4 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.1 0.4 GO:0004568 chitinase activity(GO:0004568)
0.1 0.4 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 1.8 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 1.4 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.5 GO:0050436 microfibril binding(GO:0050436)
0.1 0.8 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 3.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.9 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.3 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.8 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.3 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.4 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.5 GO:0045545 syndecan binding(GO:0045545)
0.1 0.3 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 1.0 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 0.3 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 3.0 GO:0030507 spectrin binding(GO:0030507)
0.0 0.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.2 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.5 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.7 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.7 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.2 GO:0033142 progesterone receptor binding(GO:0033142)
0.0 0.2 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.4 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.5 GO:0030553 cGMP binding(GO:0030553)
0.0 0.7 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 1.5 GO:0017022 myosin binding(GO:0017022)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.7 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.2 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.4 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.2 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.4 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.0 GO:0070140 isopeptidase activity(GO:0070122) ubiquitin-like protein-specific isopeptidase activity(GO:0070138) SUMO-specific isopeptidase activity(GO:0070140)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.7 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin binding(GO:0030332)
0.0 0.3 GO:0070064 proline-rich region binding(GO:0070064)
0.0 1.7 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.9 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 0.3 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.0 GO:0004994 somatostatin receptor activity(GO:0004994)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 PID_CONE_PATHWAY Visual signal transduction: Cones
0.1 0.4 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 5.2 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 0.7 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 0.8 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.9 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 1.5 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.3 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.0 1.2 ST_GAQ_PATHWAY G alpha q Pathway
0.0 1.0 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.6 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.5 PID_PI3KCI_AKT_PATHWAY Class I PI3K signaling events mediated by Akt
0.0 1.2 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.0 1.6 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.3 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.8 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 0.7 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 4.0 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 0.3 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 2.0 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.3 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 0.7 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.4 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.9 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.9 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.4 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 1.2 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.0 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.4 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.6 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.2 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.4 REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.3 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.2 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.2 REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.7 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.1 REACTOME_SIGNALING_BY_EGFR_IN_CANCER Genes involved in Signaling by EGFR in Cancer