Motif ID: Spib
Z-value: 0.808

Transcription factors associated with Spib:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Spib | ENSMUSG00000008193.7 | Spib |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.4 | 4.1 | GO:0002865 | negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865) |
0.7 | 2.2 | GO:0002538 | arachidonic acid metabolite production involved in inflammatory response(GO:0002538) |
0.7 | 4.4 | GO:0021797 | forebrain anterior/posterior pattern specification(GO:0021797) |
0.7 | 4.3 | GO:1901164 | negative regulation of trophoblast cell migration(GO:1901164) |
0.5 | 3.1 | GO:0032796 | uropod organization(GO:0032796) |
0.5 | 2.5 | GO:0003105 | negative regulation of glomerular filtration(GO:0003105) |
0.4 | 1.2 | GO:0016344 | meiotic chromosome movement towards spindle pole(GO:0016344) |
0.4 | 1.2 | GO:0001788 | antibody-dependent cellular cytotoxicity(GO:0001788) |
0.4 | 1.9 | GO:1902683 | regulation of receptor localization to synapse(GO:1902683) |
0.4 | 1.4 | GO:0010808 | positive regulation of synaptic vesicle priming(GO:0010808) |
0.3 | 2.1 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
0.3 | 1.0 | GO:1904809 | dense core granule localization(GO:0032253) dense core granule transport(GO:1901950) regulation of dense core granule transport(GO:1904809) positive regulation of dense core granule transport(GO:1904811) |
0.3 | 1.0 | GO:1902277 | negative regulation of pancreatic amylase secretion(GO:1902277) |
0.3 | 0.9 | GO:0050859 | negative regulation of B cell receptor signaling pathway(GO:0050859) |
0.3 | 1.4 | GO:0098706 | ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706) |
0.3 | 1.6 | GO:0042699 | follicle-stimulating hormone signaling pathway(GO:0042699) |
0.3 | 0.8 | GO:1903774 | positive regulation of viral budding via host ESCRT complex(GO:1903774) |
0.2 | 0.7 | GO:1903538 | meiotic sister chromatid cohesion, centromeric(GO:0051754) meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538) |
0.2 | 0.7 | GO:0070315 | G1 to G0 transition involved in cell differentiation(GO:0070315) |
0.2 | 1.6 | GO:1990573 | potassium ion import across plasma membrane(GO:1990573) |
0.2 | 1.1 | GO:1901843 | positive regulation of high voltage-gated calcium channel activity(GO:1901843) |
0.2 | 0.6 | GO:0099552 | trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553) regulation of intracellular calcium activated chloride channel activity(GO:1902938) |
0.2 | 0.6 | GO:0070944 | neutrophil mediated killing of bacterium(GO:0070944) |
0.2 | 1.8 | GO:0050908 | detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962) |
0.2 | 0.8 | GO:1903984 | positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984) |
0.2 | 0.6 | GO:2000812 | regulation of barbed-end actin filament capping(GO:2000812) |
0.2 | 0.8 | GO:0035617 | stress granule disassembly(GO:0035617) plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386) regulation of voltage-gated sodium channel activity(GO:1905150) |
0.2 | 0.9 | GO:0035469 | determination of pancreatic left/right asymmetry(GO:0035469) |
0.1 | 3.0 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
0.1 | 0.4 | GO:0019676 | ammonia assimilation cycle(GO:0019676) |
0.1 | 0.4 | GO:0003219 | cardiac right ventricle formation(GO:0003219) |
0.1 | 0.8 | GO:0002710 | negative regulation of T cell mediated immunity(GO:0002710) |
0.1 | 0.6 | GO:1900095 | regulation of dosage compensation by inactivation of X chromosome(GO:1900095) |
0.1 | 0.7 | GO:0034058 | endosomal vesicle fusion(GO:0034058) |
0.1 | 0.3 | GO:0035359 | negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) cell proliferation involved in heart valve development(GO:2000793) |
0.1 | 1.2 | GO:1901844 | regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) |
0.1 | 0.6 | GO:0090383 | phagosome acidification(GO:0090383) |
0.1 | 0.7 | GO:0030579 | ubiquitin-dependent SMAD protein catabolic process(GO:0030579) |
0.1 | 0.7 | GO:1900194 | negative regulation of oocyte maturation(GO:1900194) |
0.1 | 1.4 | GO:0060670 | branching involved in labyrinthine layer morphogenesis(GO:0060670) |
0.1 | 1.2 | GO:0050849 | negative regulation of calcium-mediated signaling(GO:0050849) |
0.1 | 0.6 | GO:0006621 | protein retention in ER lumen(GO:0006621) |
0.1 | 0.4 | GO:1904425 | negative regulation of GTP binding(GO:1904425) |
0.1 | 2.4 | GO:0048268 | clathrin coat assembly(GO:0048268) |
0.1 | 0.3 | GO:0002667 | lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) |
0.1 | 0.3 | GO:0045658 | regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659) |
0.1 | 2.2 | GO:0015991 | ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662) |
0.1 | 0.2 | GO:0002322 | B cell proliferation involved in immune response(GO:0002322) |
0.1 | 0.3 | GO:0010920 | negative regulation of inositol phosphate biosynthetic process(GO:0010920) |
0.1 | 0.5 | GO:0071361 | cellular response to ethanol(GO:0071361) |
0.1 | 0.6 | GO:0035887 | aortic smooth muscle cell differentiation(GO:0035887) |
0.1 | 0.2 | GO:1904059 | regulation of locomotor rhythm(GO:1904059) |
0.1 | 0.2 | GO:1900149 | positive regulation of Schwann cell migration(GO:1900149) |
0.1 | 0.2 | GO:0090327 | negative regulation of locomotion involved in locomotory behavior(GO:0090327) |
0.1 | 0.3 | GO:0033087 | negative regulation of immature T cell proliferation(GO:0033087) |
0.1 | 0.3 | GO:0001787 | natural killer cell proliferation(GO:0001787) |
0.1 | 0.4 | GO:1905244 | regulation of modification of synaptic structure(GO:1905244) |
0.1 | 0.5 | GO:1902255 | positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255) |
0.1 | 0.2 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
0.1 | 0.4 | GO:1990118 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
0.1 | 0.6 | GO:1903301 | positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301) |
0.1 | 0.6 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
0.1 | 2.2 | GO:0007218 | neuropeptide signaling pathway(GO:0007218) |
0.1 | 1.2 | GO:0002091 | negative regulation of receptor internalization(GO:0002091) |
0.1 | 0.2 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
0.0 | 0.8 | GO:2000251 | positive regulation of actin cytoskeleton reorganization(GO:2000251) |
0.0 | 0.2 | GO:0090038 | negative regulation of protein kinase C signaling(GO:0090038) |
0.0 | 0.1 | GO:0035880 | embryonic nail plate morphogenesis(GO:0035880) positive regulation of catagen(GO:0051795) |
0.0 | 0.7 | GO:0071712 | ER-associated misfolded protein catabolic process(GO:0071712) |
0.0 | 1.3 | GO:0018345 | protein palmitoylation(GO:0018345) |
0.0 | 0.2 | GO:1903028 | regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028) |
0.0 | 1.1 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
0.0 | 0.3 | GO:0048793 | pronephros development(GO:0048793) |
0.0 | 0.2 | GO:0010735 | positive regulation of transcription via serum response element binding(GO:0010735) |
0.0 | 0.1 | GO:0001928 | regulation of exocyst assembly(GO:0001928) |
0.0 | 0.2 | GO:1990564 | protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592) |
0.0 | 3.7 | GO:0032091 | negative regulation of protein binding(GO:0032091) |
0.0 | 0.9 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
0.0 | 0.4 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
0.0 | 0.2 | GO:0051461 | regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461) |
0.0 | 0.2 | GO:0046007 | negative regulation of activated T cell proliferation(GO:0046007) |
0.0 | 0.3 | GO:0090435 | protein localization to nuclear envelope(GO:0090435) |
0.0 | 0.9 | GO:0045026 | plasma membrane fusion(GO:0045026) |
0.0 | 0.9 | GO:0035116 | embryonic hindlimb morphogenesis(GO:0035116) |
0.0 | 1.5 | GO:0038083 | peptidyl-tyrosine autophosphorylation(GO:0038083) |
0.0 | 1.0 | GO:0006879 | cellular iron ion homeostasis(GO:0006879) |
0.0 | 0.2 | GO:0090043 | regulation of tubulin deacetylation(GO:0090043) |
0.0 | 0.1 | GO:0034162 | toll-like receptor 9 signaling pathway(GO:0034162) |
0.0 | 0.3 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
0.0 | 0.2 | GO:0043923 | positive regulation by host of viral transcription(GO:0043923) |
0.0 | 0.3 | GO:0019363 | pyridine nucleotide biosynthetic process(GO:0019363) |
0.0 | 0.5 | GO:0071353 | cellular response to interleukin-4(GO:0071353) |
0.0 | 0.8 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
0.0 | 0.4 | GO:0006308 | DNA catabolic process(GO:0006308) |
0.0 | 0.2 | GO:0051574 | positive regulation of histone H3-K9 methylation(GO:0051574) |
0.0 | 0.3 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
0.0 | 0.4 | GO:0030866 | cortical actin cytoskeleton organization(GO:0030866) |
0.0 | 1.0 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
0.0 | 0.2 | GO:0090308 | regulation of methylation-dependent chromatin silencing(GO:0090308) |
0.0 | 0.2 | GO:0007250 | activation of NF-kappaB-inducing kinase activity(GO:0007250) |
0.0 | 0.1 | GO:0097039 | protein linear polyubiquitination(GO:0097039) |
0.0 | 0.2 | GO:0034244 | negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244) |
0.0 | 1.0 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
0.0 | 0.6 | GO:0061512 | protein localization to cilium(GO:0061512) |
0.0 | 0.8 | GO:0051865 | protein autoubiquitination(GO:0051865) |
0.0 | 0.3 | GO:0006903 | vesicle targeting(GO:0006903) |
0.0 | 0.4 | GO:0009299 | mRNA transcription(GO:0009299) |
0.0 | 0.5 | GO:0006376 | mRNA splice site selection(GO:0006376) |
0.0 | 0.2 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclase activity(GO:0031280) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 2.2 | GO:0099631 | postsynaptic endocytic zone cytoplasmic component(GO:0099631) |
0.6 | 2.2 | GO:0070436 | Grb2-EGFR complex(GO:0070436) |
0.3 | 1.4 | GO:0098831 | presynaptic active zone cytoplasmic component(GO:0098831) |
0.3 | 3.1 | GO:0032426 | stereocilium tip(GO:0032426) |
0.2 | 1.4 | GO:0097443 | sorting endosome(GO:0097443) |
0.2 | 1.5 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
0.1 | 1.2 | GO:0030478 | actin cap(GO:0030478) |
0.1 | 0.6 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
0.1 | 1.6 | GO:0031143 | pseudopodium(GO:0031143) |
0.1 | 0.8 | GO:0000813 | ESCRT I complex(GO:0000813) |
0.1 | 0.6 | GO:0000836 | ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836) |
0.1 | 0.7 | GO:0036513 | Derlin-1 retrotranslocation complex(GO:0036513) |
0.1 | 3.0 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
0.1 | 0.4 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
0.1 | 1.0 | GO:0030008 | TRAPP complex(GO:0030008) |
0.1 | 1.1 | GO:0071564 | npBAF complex(GO:0071564) |
0.1 | 0.6 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
0.1 | 0.4 | GO:0098837 | postsynaptic recycling endosome(GO:0098837) |
0.1 | 0.5 | GO:0002177 | manchette(GO:0002177) |
0.1 | 0.6 | GO:0033176 | proton-transporting V-type ATPase complex(GO:0033176) |
0.1 | 0.8 | GO:0017119 | Golgi transport complex(GO:0017119) |
0.0 | 0.9 | GO:0033178 | proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178) |
0.0 | 0.3 | GO:0098554 | cytoplasmic side of endoplasmic reticulum membrane(GO:0098554) |
0.0 | 0.3 | GO:0033263 | CORVET complex(GO:0033263) |
0.0 | 0.3 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
0.0 | 0.2 | GO:0070847 | core mediator complex(GO:0070847) |
0.0 | 0.8 | GO:0035253 | ciliary rootlet(GO:0035253) |
0.0 | 0.2 | GO:0035032 | phosphatidylinositol 3-kinase complex, class III(GO:0035032) |
0.0 | 0.7 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
0.0 | 0.8 | GO:0097386 | glial cell projection(GO:0097386) |
0.0 | 0.2 | GO:0033503 | HULC complex(GO:0033503) |
0.0 | 2.2 | GO:0030315 | T-tubule(GO:0030315) |
0.0 | 3.4 | GO:0043204 | perikaryon(GO:0043204) |
0.0 | 2.5 | GO:0016328 | lateral plasma membrane(GO:0016328) |
0.0 | 1.0 | GO:0016592 | mediator complex(GO:0016592) |
0.0 | 3.7 | GO:0043195 | terminal bouton(GO:0043195) |
0.0 | 0.1 | GO:0071797 | LUBAC complex(GO:0071797) |
0.0 | 0.2 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
0.0 | 0.2 | GO:0060091 | kinocilium(GO:0060091) |
0.0 | 1.8 | GO:0005581 | collagen trimer(GO:0005581) |
0.0 | 3.5 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
0.0 | 0.8 | GO:0045335 | phagocytic vesicle(GO:0045335) |
0.0 | 0.3 | GO:0042581 | specific granule(GO:0042581) |
0.0 | 0.5 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
0.0 | 0.4 | GO:0097225 | sperm midpiece(GO:0097225) |
0.0 | 0.6 | GO:0051233 | spindle midzone(GO:0051233) |
0.0 | 0.1 | GO:0071203 | WASH complex(GO:0071203) |
0.0 | 0.5 | GO:0071010 | prespliceosome(GO:0071010) |
0.0 | 0.1 | GO:0005787 | signal peptidase complex(GO:0005787) |
0.0 | 0.2 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
0.0 | 0.5 | GO:0032040 | small-subunit processome(GO:0032040) |
0.0 | 0.3 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
0.0 | 0.1 | GO:0043527 | tRNA methyltransferase complex(GO:0043527) |
0.0 | 1.1 | GO:0005643 | nuclear pore(GO:0005643) |
0.0 | 0.2 | GO:0000124 | SAGA complex(GO:0000124) |
0.0 | 0.9 | GO:0030139 | endocytic vesicle(GO:0030139) |
0.0 | 0.3 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
0.0 | 1.3 | GO:0008021 | synaptic vesicle(GO:0008021) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 3.7 | GO:0004111 | creatine kinase activity(GO:0004111) |
0.6 | 4.3 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
0.5 | 1.6 | GO:0031896 | V2 vasopressin receptor binding(GO:0031896) |
0.5 | 2.1 | GO:0042328 | heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328) |
0.4 | 2.2 | GO:0050544 | arachidonic acid binding(GO:0050544) |
0.3 | 1.6 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
0.3 | 1.6 | GO:0019770 | IgG receptor activity(GO:0019770) |
0.3 | 3.1 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
0.2 | 3.7 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
0.2 | 2.2 | GO:0005168 | neurotrophin TRKA receptor binding(GO:0005168) |
0.2 | 2.1 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
0.2 | 2.2 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
0.2 | 2.2 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
0.2 | 0.6 | GO:0001639 | PLC activating G-protein coupled glutamate receptor activity(GO:0001639) A2A adenosine receptor binding(GO:0031687) G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530) |
0.2 | 0.6 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
0.1 | 0.4 | GO:0016880 | acid-ammonia (or amide) ligase activity(GO:0016880) |
0.1 | 0.7 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
0.1 | 0.5 | GO:0031727 | CCR2 chemokine receptor binding(GO:0031727) |
0.1 | 1.8 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
0.1 | 0.5 | GO:0004609 | phosphatidylserine decarboxylase activity(GO:0004609) |
0.1 | 3.6 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
0.1 | 0.8 | GO:0099609 | microtubule lateral binding(GO:0099609) |
0.1 | 0.8 | GO:0046790 | virion binding(GO:0046790) |
0.1 | 0.7 | GO:0032184 | SUMO polymer binding(GO:0032184) |
0.1 | 0.7 | GO:0031432 | titin binding(GO:0031432) |
0.1 | 0.2 | GO:0071568 | UFM1 transferase activity(GO:0071568) |
0.1 | 0.3 | GO:0010484 | H3 histone acetyltransferase activity(GO:0010484) |
0.1 | 1.3 | GO:0050811 | GABA receptor binding(GO:0050811) |
0.1 | 0.3 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
0.1 | 0.5 | GO:1990948 | ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948) |
0.1 | 1.2 | GO:0042043 | neurexin family protein binding(GO:0042043) |
0.1 | 0.6 | GO:0003873 | 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) |
0.1 | 0.8 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
0.1 | 0.4 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
0.1 | 1.1 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
0.1 | 0.3 | GO:0051425 | PTB domain binding(GO:0051425) |
0.0 | 0.4 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
0.0 | 0.8 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
0.0 | 1.1 | GO:0035613 | RNA stem-loop binding(GO:0035613) |
0.0 | 1.3 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
0.0 | 2.0 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
0.0 | 0.7 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
0.0 | 0.2 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
0.0 | 0.4 | GO:0016888 | endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888) |
0.0 | 0.9 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
0.0 | 1.2 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
0.0 | 0.5 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
0.0 | 1.1 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
0.0 | 0.2 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
0.0 | 6.5 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
0.0 | 1.7 | GO:0042974 | retinoic acid receptor binding(GO:0042974) |
0.0 | 0.2 | GO:0030911 | TPR domain binding(GO:0030911) |
0.0 | 0.6 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
0.0 | 0.2 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
0.0 | 3.4 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
0.0 | 0.3 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
0.0 | 0.4 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
0.0 | 0.3 | GO:0005537 | mannose binding(GO:0005537) |
0.0 | 3.4 | GO:0017124 | SH3 domain binding(GO:0017124) |
0.0 | 3.9 | GO:0030246 | carbohydrate binding(GO:0030246) |
0.0 | 0.9 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
0.0 | 0.1 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
0.0 | 1.4 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.0 | 0.4 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.0 | 0.1 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
0.0 | 0.8 | GO:0001104 | RNA polymerase II transcription cofactor activity(GO:0001104) |
0.0 | 1.6 | GO:0042626 | ATPase activity, coupled to transmembrane movement of substances(GO:0042626) |
0.0 | 0.3 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
0.0 | 0.7 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
0.0 | 0.5 | GO:0036002 | pre-mRNA binding(GO:0036002) |
0.0 | 0.1 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
0.0 | 0.2 | GO:0031690 | adrenergic receptor binding(GO:0031690) |
0.0 | 0.9 | GO:0004714 | transmembrane receptor protein tyrosine kinase activity(GO:0004714) |
0.0 | 0.4 | GO:0050699 | WW domain binding(GO:0050699) |
0.0 | 0.6 | GO:0001540 | beta-amyloid binding(GO:0001540) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 4.9 | SA_PTEN_PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
0.1 | 5.2 | PID_CASPASE_PATHWAY | Caspase cascade in apoptosis |
0.1 | 2.1 | PID_ARF_3PATHWAY | Arf1 pathway |
0.1 | 2.1 | PID_IL8_CXCR2_PATHWAY | IL8- and CXCR2-mediated signaling events |
0.1 | 2.6 | PID_TCR_PATHWAY | TCR signaling in naïve CD4+ T cells |
0.0 | 3.1 | PID_BCR_5PATHWAY | BCR signaling pathway |
0.0 | 1.6 | ST_G_ALPHA_I_PATHWAY | G alpha i Pathway |
0.0 | 1.8 | PID_KIT_PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
0.0 | 1.7 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
0.0 | 1.8 | PID_ERBB1_INTERNALIZATION_PATHWAY | Internalization of ErbB1 |
0.0 | 0.3 | PID_AR_NONGENOMIC_PATHWAY | Nongenotropic Androgen signaling |
0.0 | 0.6 | PID_RAC1_PATHWAY | RAC1 signaling pathway |
0.0 | 1.3 | SIG_CHEMOTAXIS | Genes related to chemotaxis |
0.0 | 0.6 | PID_HIF1A_PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
0.0 | 0.2 | PID_EPHA2_FWD_PATHWAY | EPHA2 forward signaling |
0.0 | 0.8 | PID_NCADHERIN_PATHWAY | N-cadherin signaling events |
0.0 | 2.6 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.0 | 0.3 | PID_HIF2PATHWAY | HIF-2-alpha transcription factor network |
0.0 | 0.3 | PID_ANGIOPOIETIN_RECEPTOR_PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
0.0 | 0.2 | PID_FCER1_PATHWAY | Fc-epsilon receptor I signaling in mast cells |
0.0 | 0.3 | PID_TNF_PATHWAY | TNF receptor signaling pathway |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 3.0 | REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
0.2 | 2.3 | REACTOME_CD28_DEPENDENT_VAV1_PATHWAY | Genes involved in CD28 dependent Vav1 pathway |
0.1 | 0.9 | REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
0.1 | 1.4 | REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
0.1 | 2.8 | REACTOME_INSULIN_RECEPTOR_RECYCLING | Genes involved in Insulin receptor recycling |
0.1 | 2.2 | REACTOME_GAP_JUNCTION_DEGRADATION | Genes involved in Gap junction degradation |
0.1 | 1.6 | REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
0.1 | 1.6 | REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS | Genes involved in Thrombin signalling through proteinase activated receptors (PARs) |
0.1 | 0.3 | REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS | Genes involved in Hormone ligand-binding receptors |
0.1 | 3.3 | REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING | Genes involved in Sema4D in semaphorin signaling |
0.1 | 3.7 | REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS | Genes involved in Glucagon-type ligand receptors |
0.1 | 0.8 | REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
0.1 | 0.8 | REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
0.1 | 0.6 | REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING | Genes involved in Spry regulation of FGF signaling |
0.1 | 2.1 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
0.0 | 1.1 | REACTOME_EGFR_DOWNREGULATION | Genes involved in EGFR downregulation |
0.0 | 1.0 | REACTOME_KINESINS | Genes involved in Kinesins |
0.0 | 1.0 | REACTOME_RAP1_SIGNALLING | Genes involved in Rap1 signalling |
0.0 | 0.8 | REACTOME_DARPP_32_EVENTS | Genes involved in DARPP-32 events |
0.0 | 1.8 | REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS | Genes involved in Peptide ligand-binding receptors |
0.0 | 0.2 | REACTOME_P2Y_RECEPTORS | Genes involved in P2Y receptors |
0.0 | 3.5 | REACTOME_SIGNALING_BY_RHO_GTPASES | Genes involved in Signaling by Rho GTPases |
0.0 | 0.4 | REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
0.0 | 1.6 | REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
0.0 | 0.4 | REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
0.0 | 0.2 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
0.0 | 0.2 | REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
0.0 | 0.6 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
0.0 | 1.1 | REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
0.0 | 1.0 | REACTOME_INTEGRATION_OF_ENERGY_METABOLISM | Genes involved in Integration of energy metabolism |
0.0 | 0.8 | REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION | Genes involved in Antigen processing-Cross presentation |
0.0 | 0.4 | REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |