Motif ID: Hmga2

Z-value: 1.357


Transcription factors associated with Hmga2:

Gene SymbolEntrez IDGene Name
Hmga2 ENSMUSG00000056758.8 Hmga2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hmga2mm10_v2_chr10_-_120476469_120476527-0.305.7e-02Click!


Activity profile for motif Hmga2.

activity profile for motif Hmga2


Sorted Z-values histogram for motif Hmga2

Sorted Z-values for motif Hmga2



Network of associatons between targets according to the STRING database.



First level regulatory network of Hmga2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_98667264 10.667 ENSMUST00000099683.1
Gm10800
predicted gene 10800
chr9_+_3013140 10.601 ENSMUST00000143083.2
Gm10721
predicted gene 10721
chr14_-_19418930 10.121 ENSMUST00000177817.1
Gm21738
predicted gene, 21738
chr9_+_3004457 8.561 ENSMUST00000178348.1
Gm11168
predicted gene 11168
chr9_+_3023547 7.059 ENSMUST00000099046.3
Gm10718
predicted gene 10718
chr9_+_3025417 7.032 ENSMUST00000075573.6
Gm10717
predicted gene 10717
chr9_+_3018753 6.437 ENSMUST00000179272.1
Gm10719
predicted gene 10719
chr9_+_3017408 5.930 ENSMUST00000099049.3
Gm10719
predicted gene 10719
chr11_-_102897123 4.565 ENSMUST00000067444.3
Gfap
glial fibrillary acidic protein
chr11_-_102897146 3.826 ENSMUST00000077902.4
Gfap
glial fibrillary acidic protein
chr16_-_43979050 2.958 ENSMUST00000165648.1
ENSMUST00000036321.7
Zdhhc23

zinc finger, DHHC domain containing 23

chr4_+_44756553 2.813 ENSMUST00000107824.2
Zcchc7
zinc finger, CCHC domain containing 7
chr2_+_158375638 2.525 ENSMUST00000109488.1
Snhg11
small nucleolar RNA host gene 11
chr4_+_44756609 2.219 ENSMUST00000143385.1
Zcchc7
zinc finger, CCHC domain containing 7
chr13_-_62371936 2.100 ENSMUST00000107989.3
Gm3604
predicted gene 3604
chr9_-_123260776 2.068 ENSMUST00000068140.4
Tmem158
transmembrane protein 158
chr16_+_96361749 2.030 ENSMUST00000000163.6
ENSMUST00000081093.3
ENSMUST00000113795.1
Igsf5


immunoglobulin superfamily, member 5


chr5_-_106926245 2.002 ENSMUST00000117588.1
Hfm1
HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
chrX_-_164980310 1.934 ENSMUST00000004715.1
ENSMUST00000112248.2
Mospd2

motile sperm domain containing 2

chr5_+_14514918 1.824 ENSMUST00000030691.10
ENSMUST00000182407.1
Pclo

piccolo (presynaptic cytomatrix protein)

chr13_-_74482943 1.816 ENSMUST00000074369.6
Zfp825
zinc finger protein 825
chr18_+_37447641 1.702 ENSMUST00000052387.3
Pcdhb14
protocadherin beta 14
chrX_+_101640056 1.689 ENSMUST00000119299.1
ENSMUST00000044475.4
Ogt

O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)

chr2_+_19344317 1.680 ENSMUST00000141289.1
4930447M23Rik
RIKEN cDNA 4930447M23 gene
chr14_-_36919314 1.636 ENSMUST00000182797.1
Ccser2
coiled-coil serine rich 2
chr4_+_103114712 1.611 ENSMUST00000143417.1
Mier1
mesoderm induction early response 1 homolog (Xenopus laevis
chr14_-_36919513 1.606 ENSMUST00000182042.1
Ccser2
coiled-coil serine rich 2
chr4_-_32923455 1.579 ENSMUST00000035719.4
ENSMUST00000084749.1
Ankrd6

ankyrin repeat domain 6

chr16_+_96235801 1.538 ENSMUST00000113800.2
B3galt5
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5
chr7_-_46672537 1.501 ENSMUST00000049298.7
Tph1
tryptophan hydroxylase 1
chr2_+_29124106 1.494 ENSMUST00000129544.1
Setx
senataxin
chr7_-_12422488 1.433 ENSMUST00000120220.1
Zfp551
zinc fingr protein 551
chr19_-_5510467 1.353 ENSMUST00000070172.4
Snx32
sorting nexin 32
chr7_-_5413145 1.352 ENSMUST00000108569.2
Vmn1r58
vomeronasal 1 receptor 58
chr2_-_122702615 1.314 ENSMUST00000005952.4
ENSMUST00000099457.3
Slc30a4

solute carrier family 30 (zinc transporter), member 4

chr1_+_93235836 1.282 ENSMUST00000062202.7
Sned1
sushi, nidogen and EGF-like domains 1
chr16_-_45742888 1.245 ENSMUST00000128348.1
ENSMUST00000066983.6
Abhd10

abhydrolase domain containing 10

chr6_-_113719880 1.224 ENSMUST00000064993.5
Ghrl
ghrelin
chr16_-_36784784 1.193 ENSMUST00000165531.1
Slc15a2
solute carrier family 15 (H+/peptide transporter), member 2
chr1_+_46066738 1.185 ENSMUST00000069293.7
Dnah7b
dynein, axonemal, heavy chain 7B
chr7_-_42642547 1.148 ENSMUST00000098503.2
9830147E19Rik
RIKEN cDNA 9830147E19 gene
chrM_+_10167 1.139 ENSMUST00000082414.1
mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr2_+_91237110 1.135 ENSMUST00000181191.1
A330069E16Rik
RIKEN cDNA A330069E16 gene
chr6_+_21949571 1.127 ENSMUST00000031680.3
ENSMUST00000115389.1
ENSMUST00000151473.1
Ing3


inhibitor of growth family, member 3


chr3_+_88214474 1.127 ENSMUST00000181356.1
ENSMUST00000181396.1
Gm3764

predicted gene 3764

chr14_-_100149764 1.101 ENSMUST00000097079.4
Klf12
Kruppel-like factor 12
chr9_-_97111117 1.089 ENSMUST00000085206.4
Slc25a36
solute carrier family 25, member 36
chr17_+_40811089 1.056 ENSMUST00000024721.7
Rhag
Rhesus blood group-associated A glycoprotein
chr13_-_62607499 1.045 ENSMUST00000091563.4
6720489N17Rik
RIKEN cDNA 6720489N17 gene
chrX_+_103356464 1.042 ENSMUST00000116547.2
Chic1
cysteine-rich hydrophobic domain 1
chr8_-_84176552 1.037 ENSMUST00000070102.5
Nanos3
nanos homolog 3 (Drosophila)
chr7_-_12422751 0.984 ENSMUST00000080348.5
Zfp551
zinc fingr protein 551
chr14_+_25980039 0.921 ENSMUST00000173155.1
Duxbl1
double homeobox B-like 1
chr10_+_69787431 0.902 ENSMUST00000183240.1
Ank3
ankyrin 3, epithelial
chr16_+_87454976 0.897 ENSMUST00000119504.1
ENSMUST00000131356.1
Usp16

ubiquitin specific peptidase 16

chr11_+_75999912 0.875 ENSMUST00000066408.5
1700016K19Rik
RIKEN cDNA 1700016K19 gene
chrX_+_37126777 0.867 ENSMUST00000016553.4
Nkap
NFKB activating protein
chr11_-_83302586 0.859 ENSMUST00000176374.1
Pex12
peroxisomal biogenesis factor 12
chr10_+_58446845 0.813 ENSMUST00000003310.5
Ranbp2
RAN binding protein 2
chr2_+_5951440 0.807 ENSMUST00000060092.6
Upf2
UPF2 regulator of nonsense transcripts homolog (yeast)
chr7_+_49975228 0.800 ENSMUST00000107603.1
Nell1
NEL-like 1
chr2_-_30359278 0.773 ENSMUST00000163668.2
ENSMUST00000028214.8
ENSMUST00000113621.3
Sh3glb2


SH3-domain GRB2-like endophilin B2


chr4_+_126286792 0.767 ENSMUST00000070132.6
Col8a2
collagen, type VIII, alpha 2
chrM_+_9870 0.745 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr3_+_135485605 0.719 ENSMUST00000029814.9
Manba
mannosidase, beta A, lysosomal
chr2_-_148732457 0.670 ENSMUST00000028926.6
Napb
N-ethylmaleimide sensitive fusion protein attachment protein beta
chr16_-_36784924 0.667 ENSMUST00000168279.1
ENSMUST00000164579.1
ENSMUST00000023616.2
Slc15a2


solute carrier family 15 (H+/peptide transporter), member 2


chr2_-_30359190 0.667 ENSMUST00000100215.4
ENSMUST00000113620.3
Sh3glb2

SH3-domain GRB2-like endophilin B2

chr18_+_37411674 0.664 ENSMUST00000051126.2
Pcdhb10
protocadherin beta 10
chr7_-_29853611 0.653 ENSMUST00000085792.4
ENSMUST00000108223.1
Zfp940

zinc finger protein 940

chr7_+_45526330 0.646 ENSMUST00000120985.1
ENSMUST00000051810.8
Plekha4

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4

chr3_+_53845086 0.645 ENSMUST00000108014.1
Gm10985
predicted gene 10985
chr11_-_116307168 0.639 ENSMUST00000124281.1
Exoc7
exocyst complex component 7
chr9_+_88581036 0.629 ENSMUST00000164661.2
Trim43a
tripartite motif-containing 43A
chr1_+_172698046 0.627 ENSMUST00000038495.3
Crp
C-reactive protein, pentraxin-related
chr12_-_23780265 0.625 ENSMUST00000072014.4
Gm10330
predicted gene 10330
chr19_-_11818806 0.612 ENSMUST00000075304.6
Stx3
syntaxin 3
chr16_+_29579331 0.583 ENSMUST00000160597.1
Opa1
optic atrophy 1
chr10_+_90071095 0.573 ENSMUST00000183109.1
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chrM_+_9452 0.568 ENSMUST00000082411.1
mt-Nd3
mitochondrially encoded NADH dehydrogenase 3
chr17_-_6961156 0.545 ENSMUST00000063683.6
Tagap1
T cell activation GTPase activating protein 1
chr5_-_96164147 0.512 ENSMUST00000137207.1
Cnot6l
CCR4-NOT transcription complex, subunit 6-like
chr7_+_7171330 0.510 ENSMUST00000051435.7
Zfp418
zinc finger protein 418
chr1_-_24612700 0.508 ENSMUST00000088336.1
Gm10222
predicted gene 10222
chr10_+_29313500 0.503 ENSMUST00000020034.4
Echdc1
enoyl Coenzyme A hydratase domain containing 1
chr3_-_152210032 0.495 ENSMUST00000144950.1
Dnajb4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr7_+_92561141 0.495 ENSMUST00000032842.6
ENSMUST00000085017.4
Ccdc90b

coiled-coil domain containing 90B

chr7_-_84679346 0.494 ENSMUST00000069537.2
ENSMUST00000178385.1
Zfand6

zinc finger, AN1-type domain 6

chr9_+_92309362 0.492 ENSMUST00000098477.1
ENSMUST00000150594.1
1700057G04Rik

RIKEN cDNA 1700057G04 gene

chr13_+_104178797 0.481 ENSMUST00000022225.5
ENSMUST00000069187.5
Trim23

tripartite motif-containing 23

chr9_+_122351555 0.478 ENSMUST00000156520.1
Abhd5
abhydrolase domain containing 5
chr4_+_57637816 0.476 ENSMUST00000150412.1
Gm20459
predicted gene 20459
chr2_+_68104671 0.472 ENSMUST00000042456.3
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr17_+_73107982 0.471 ENSMUST00000130574.1
ENSMUST00000149064.1
ENSMUST00000067545.6
Lclat1


lysocardiolipin acyltransferase 1


chr6_+_125039760 0.466 ENSMUST00000140131.1
ENSMUST00000032480.7
Ing4

inhibitor of growth family, member 4

chr4_+_130913120 0.462 ENSMUST00000151698.1
Laptm5
lysosomal-associated protein transmembrane 5
chr11_+_22971991 0.456 ENSMUST00000049506.5
Zrsr1
zinc finger (CCCH type), RNA binding motif and serine/arginine rich 1
chr2_-_18048784 0.455 ENSMUST00000142856.1
Skida1
SKI/DACH domain containing 1
chr9_+_122351723 0.454 ENSMUST00000111497.3
Abhd5
abhydrolase domain containing 5
chr17_-_50094277 0.441 ENSMUST00000113195.1
Rftn1
raftlin lipid raft linker 1
chr4_-_120951664 0.435 ENSMUST00000106280.1
Zfp69
zinc finger protein 69
chr11_+_105178765 0.429 ENSMUST00000106939.2
Tlk2
tousled-like kinase 2 (Arabidopsis)
chr1_-_74588117 0.410 ENSMUST00000066986.6
Zfp142
zinc finger protein 142
chr18_-_80934054 0.405 ENSMUST00000091790.3
Atp9b
ATPase, class II, type 9B
chr6_-_106800051 0.397 ENSMUST00000013882.7
ENSMUST00000049675.4
ENSMUST00000113239.3
Crbn


cereblon


chr4_-_25281801 0.389 ENSMUST00000102994.3
Ufl1
UFM1 specific ligase 1
chr9_+_122923050 0.383 ENSMUST00000051667.7
ENSMUST00000148851.1
Zfp105

zinc finger protein 105

chr1_+_132008285 0.369 ENSMUST00000146432.1
Elk4
ELK4, member of ETS oncogene family
chr16_+_32277449 0.360 ENSMUST00000155649.1
ENSMUST00000014218.8
ENSMUST00000171474.1
Rnf168


ring finger protein 168


chr4_-_150003130 0.336 ENSMUST00000084117.6
H6pd
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr3_+_85574109 0.304 ENSMUST00000127348.1
ENSMUST00000107672.1
ENSMUST00000107674.1
Pet112


PET112 homolog (S. cerevisiae)


chr11_+_82035569 0.296 ENSMUST00000000193.5
Ccl2
chemokine (C-C motif) ligand 2
chr4_+_110397661 0.290 ENSMUST00000106589.2
ENSMUST00000106587.2
ENSMUST00000106591.1
ENSMUST00000106592.1
Agbl4



ATP/GTP binding protein-like 4



chr16_+_29579347 0.290 ENSMUST00000038867.6
ENSMUST00000161186.1
Opa1

optic atrophy 1

chrX_-_95956890 0.287 ENSMUST00000079987.6
ENSMUST00000113864.2
Las1l

LAS1-like (S. cerevisiae)

chr11_-_116306652 0.276 ENSMUST00000126731.1
Exoc7
exocyst complex component 7
chr11_+_83942062 0.251 ENSMUST00000049257.7
Ddx52
DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
chr4_-_58912678 0.249 ENSMUST00000144512.1
ENSMUST00000102889.3
ENSMUST00000055822.8
AI314180


expressed sequence AI314180


chr16_-_26371828 0.219 ENSMUST00000023154.2
Cldn1
claudin 1
chrX_-_38576166 0.215 ENSMUST00000050083.5
Cul4b
cullin 4B
chr12_+_69296676 0.213 ENSMUST00000021362.4
Klhdc2
kelch domain containing 2
chr14_+_52197502 0.209 ENSMUST00000180857.1
Gm26590
predicted gene, 26590
chr11_+_77462325 0.206 ENSMUST00000102493.1
Coro6
coronin 6
chr1_-_144004142 0.204 ENSMUST00000127206.1
Rgs2
regulator of G-protein signaling 2
chr17_+_8165501 0.200 ENSMUST00000097419.3
ENSMUST00000024636.8
Fgfr1op

Fgfr1 oncogene partner

chrX_-_16817339 0.194 ENSMUST00000040820.6
Maob
monoamine oxidase B
chr5_-_31220491 0.193 ENSMUST00000031032.7
Ppm1g
protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform
chr11_+_83302641 0.145 ENSMUST00000176430.1
ENSMUST00000065692.7
Ap2b1

adaptor-related protein complex 2, beta 1 subunit

chr2_-_84678828 0.129 ENSMUST00000111665.1
Tmx2
thioredoxin-related transmembrane protein 2
chr10_-_81014902 0.121 ENSMUST00000126317.1
ENSMUST00000092285.3
ENSMUST00000117805.1
Gng7


guanine nucleotide binding protein (G protein), gamma 7


chr17_+_66111605 0.114 ENSMUST00000116556.2
Wash
WAS protein family homolog
chr14_+_49172202 0.105 ENSMUST00000153488.1
Naa30
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr16_+_33185045 0.104 ENSMUST00000039733.8
Osbpl11
oxysterol binding protein-like 11
chr2_+_62664279 0.103 ENSMUST00000028257.2
Gca
grancalcin
chr5_+_31494736 0.102 ENSMUST00000076949.6
ENSMUST00000117700.1
Gpn1

GPN-loop GTPase 1

chr19_+_46689902 0.098 ENSMUST00000074912.7
2010012O05Rik
RIKEN cDNA 2010012O05 gene
chr17_+_66111529 0.087 ENSMUST00000072383.6
Wash
WAS protein family homolog
chr2_-_75981967 0.080 ENSMUST00000099994.3
Ttc30a1
tetratricopeptide repeat domain 30A1
chr8_-_85080652 0.078 ENSMUST00000152785.1
Wdr83
WD repeat domain containing 83
chr13_+_55105290 0.075 ENSMUST00000161315.1
ENSMUST00000021937.5
ENSMUST00000159278.1
ENSMUST00000159147.1
ENSMUST00000161077.1
Zfp346




zinc finger protein 346




chr11_-_116306696 0.074 ENSMUST00000133468.1
ENSMUST00000106411.3
ENSMUST00000106413.3
ENSMUST00000021147.7
Exoc7



exocyst complex component 7



chr16_-_18413452 0.059 ENSMUST00000165430.1
ENSMUST00000147720.1
Comt

catechol-O-methyltransferase

chr2_-_94157881 0.059 ENSMUST00000028619.4
Hsd17b12
hydroxysteroid (17-beta) dehydrogenase 12
chr7_-_45526146 0.056 ENSMUST00000167273.1
ENSMUST00000042105.8
Ppp1r15a

protein phosphatase 1, regulatory (inhibitor) subunit 15A

chr17_-_74459096 0.056 ENSMUST00000052124.7
Nlrc4
NLR family, CARD domain containing 4
chr9_-_8134294 0.051 ENSMUST00000037397.6
AK129341
cDNA sequence AK129341
chr9_+_70012540 0.039 ENSMUST00000118198.1
ENSMUST00000119905.1
ENSMUST00000119413.1
ENSMUST00000140305.1
ENSMUST00000122087.1
Gtf2a2




general transcription factor II A, 2




chr9_+_75037838 0.036 ENSMUST00000169188.1
Arpp19
cAMP-regulated phosphoprotein 19
chr1_+_74588347 0.014 ENSMUST00000113732.1
Bcs1l
BCS1-like (yeast)
chr8_+_119344490 0.013 ENSMUST00000034300.6
Hsbp1
heat shock factor binding protein 1
chr13_+_100107997 0.013 ENSMUST00000142155.1
ENSMUST00000022145.8
ENSMUST00000132053.1
Serf1


small EDRK-rich factor 1


chrX_+_152178945 0.011 ENSMUST00000096275.4
Iqsec2
IQ motif and Sec7 domain 2
chr11_-_3409162 0.001 ENSMUST00000101638.3
Limk2
LIM motif-containing protein kinase 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 8.4 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
0.8 2.5 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.6 1.8 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.5 1.5 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
0.4 1.2 GO:0019389 glucuronoside metabolic process(GO:0019389)
0.4 1.2 GO:0035482 intestine smooth muscle contraction(GO:0014827) gastric motility(GO:0035482) gastric emptying(GO:0035483) regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) negative regulation of tumor necrosis factor biosynthetic process(GO:0042536) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938) positive regulation of cortisol secretion(GO:0051464) regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) regulation of small intestine smooth muscle contraction(GO:1904347) small intestine smooth muscle contraction(GO:1990770)
0.4 1.9 GO:0042891 antibiotic transport(GO:0042891) dipeptide transport(GO:0042938)
0.4 1.1 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.3 0.9 GO:0016598 protein arginylation(GO:0016598)
0.3 1.1 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.2 0.9 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891) positive regulation of triglyceride catabolic process(GO:0010898)
0.2 0.9 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) histone H2A K63-linked deubiquitination(GO:0070537)
0.2 0.9 GO:0014042 positive regulation of neuron maturation(GO:0014042)
0.2 1.5 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.2 2.0 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.1 1.3 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.1 1.6 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.1 1.2 GO:0036159 inner dynein arm assembly(GO:0036159)
0.1 0.6 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 3.0 GO:0018345 protein palmitoylation(GO:0018345)
0.1 1.6 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.4 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.1 0.7 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.1 0.9 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.8 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.1 0.6 GO:0098967 synaptic vesicle docking(GO:0016081) exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 1.0 GO:0035635 entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.1 0.2 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.1 0.3 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.1 0.4 GO:0070535 histone H2A K63-linked ubiquitination(GO:0070535)
0.1 0.5 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 0.2 GO:0010519 negative regulation of phospholipase activity(GO:0010519)
0.1 1.1 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.5 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.1 0.4 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 0.2 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.1 1.1 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.3 GO:2000427 eosinophil chemotaxis(GO:0048245) T cell extravasation(GO:0072683) positive regulation of apoptotic cell clearance(GO:2000427)
0.1 0.5 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 0.5 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 1.4 GO:0006625 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.1 1.0 GO:1900153 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.4 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.6 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.7 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.8 GO:0031100 organ regeneration(GO:0031100)
0.0 3.2 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.4 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.4 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.0 0.4 GO:0070932 histone H3 deacetylation(GO:0070932)
0.0 0.1 GO:0010889 regulation of sequestering of triglyceride(GO:0010889)
0.0 0.1 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.9 GO:0030851 granulocyte differentiation(GO:0030851)
0.0 0.3 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 1.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0031335 regulation of sulfur amino acid metabolic process(GO:0031335)
0.0 0.3 GO:0000478 endonucleolytic cleavage involved in rRNA processing(GO:0000478)
0.0 0.1 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 1.1 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.0 0.5 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.2 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.1 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0070269 pyroptosis(GO:0070269)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.5 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 8.4 GO:0097450 astrocyte end-foot(GO:0097450)
0.5 1.8 GO:0099569 presynaptic cytoskeleton(GO:0099569)
0.4 1.2 GO:0036156 inner dynein arm(GO:0036156)
0.2 1.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.2 0.9 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.1 0.9 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 2.3 GO:0042588 zymogen granule(GO:0042588)
0.1 0.7 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.3 GO:0044299 C-fiber(GO:0044299)
0.1 1.0 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.5 GO:0089701 U2AF(GO:0089701)
0.0 0.9 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.4 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 1.5 GO:0045171 intercellular bridge(GO:0045171)
0.0 2.1 GO:0070469 respiratory chain(GO:0070469)
0.0 0.5 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 2.2 GO:0005923 bicellular tight junction(GO:0005923)
0.0 1.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0061702 inflammasome complex(GO:0061702)
0.0 0.9 GO:0005811 lipid particle(GO:0005811)
0.0 1.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.8 GO:0005581 collagen trimer(GO:0005581)
0.0 0.4 GO:0035861 site of double-strand break(GO:0035861)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0042936 dipeptide transporter activity(GO:0042936)
0.6 1.7 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.5 1.5 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.5 1.5 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.2 0.5 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.2 0.7 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 1.8 GO:0005522 profilin binding(GO:0005522)
0.1 0.4 GO:0071568 UFM1 transferase activity(GO:0071568)
0.1 0.9 GO:1901612 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.1 0.5 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 0.3 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.1 9.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 3.0 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.6 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 1.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 0.6 GO:0001849 complement component C1q binding(GO:0001849)
0.1 1.2 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 2.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.9 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 1.1 GO:0022842 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.1 0.3 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.2 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 1.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.7 GO:0005537 mannose binding(GO:0005537)
0.0 1.5 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 1.1 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.0 0.5 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.5 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 1.4 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 2.3 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.8 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.5 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.8 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 1.6 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.2 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.9 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.9 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.6 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 2.0 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.8 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.5 GO:0001671 ATPase activator activity(GO:0001671)
0.0 1.0 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 3.2 GO:0008017 microtubule binding(GO:0008017)
0.0 0.6 GO:0046875 ephrin receptor binding(GO:0046875)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.6 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.8 NABA_COLLAGENS Genes encoding collagen proteins
0.0 1.0 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 2.0 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.6 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 0.3 PID_IL23_PATHWAY IL23-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 8.4 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 1.5 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.1 0.6 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 1.2 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 0.8 REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1 1.1 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.6 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.9 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.9 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.8 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.9 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.8 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.4 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases