Motif ID: Zfp652

Z-value: 0.821


Transcription factors associated with Zfp652:

Gene SymbolEntrez IDGene Name
Zfp652 ENSMUSG00000075595.3 Zfp652

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp652mm10_v2_chr11_+_95712673_95712673-0.231.5e-01Click!


Activity profile for motif Zfp652.

activity profile for motif Zfp652


Sorted Z-values histogram for motif Zfp652

Sorted Z-values for motif Zfp652



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp652

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_53707532 9.988 ENSMUST00000031093.3
Cckar
cholecystokinin A receptor
chr10_+_26229707 6.770 ENSMUST00000060716.5
ENSMUST00000164660.1
Samd3

sterile alpha motif domain containing 3

chr16_+_30065333 6.567 ENSMUST00000023171.7
Hes1
hairy and enhancer of split 1 (Drosophila)
chr3_+_87971129 4.522 ENSMUST00000160694.1
Nes
nestin
chr3_+_87971071 4.514 ENSMUST00000090973.5
Nes
nestin
chr1_+_153665666 4.479 ENSMUST00000111814.1
ENSMUST00000111810.1
Rgs8

regulator of G-protein signaling 8

chr1_+_153665274 4.195 ENSMUST00000152114.1
ENSMUST00000111812.1
Rgs8

regulator of G-protein signaling 8

chr10_-_92165159 4.035 ENSMUST00000182567.1
ENSMUST00000181604.2
ENSMUST00000181213.1
Rmst


rhabdomyosarcoma 2 associated transcript (non-coding RNA)


chr4_-_63403330 3.743 ENSMUST00000035724.4
Akna
AT-hook transcription factor
chr1_-_138847579 3.647 ENSMUST00000093486.3
ENSMUST00000046870.6
Lhx9

LIM homeobox protein 9

chr1_+_153665587 3.512 ENSMUST00000147700.1
Rgs8
regulator of G-protein signaling 8
chr5_+_115908644 3.439 ENSMUST00000141101.1
Cit
citron
chr1_+_153665627 3.435 ENSMUST00000147482.1
Rgs8
regulator of G-protein signaling 8
chr1_+_184034381 3.183 ENSMUST00000048655.7
Dusp10
dual specificity phosphatase 10
chr11_+_98960412 3.149 ENSMUST00000107473.2
Rara
retinoic acid receptor, alpha
chr10_-_6980376 3.055 ENSMUST00000105617.1
Ipcef1
interaction protein for cytohesin exchange factors 1
chrX_-_48034842 2.974 ENSMUST00000039026.7
Apln
apelin
chr7_-_25788635 2.898 ENSMUST00000002677.4
ENSMUST00000085948.4
Axl

AXL receptor tyrosine kinase

chr2_+_167777467 2.389 ENSMUST00000139927.1
ENSMUST00000127441.1
Gm14321

predicted gene 14321

chr9_-_108452377 2.306 ENSMUST00000035232.7
Klhdc8b
kelch domain containing 8B
chr6_+_137754529 2.129 ENSMUST00000087675.6
Dera
2-deoxyribose-5-phosphate aldolase homolog (C. elegans)
chr11_-_94242701 2.128 ENSMUST00000061469.3
Wfikkn2
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr19_-_4928241 2.101 ENSMUST00000025851.3
Dpp3
dipeptidylpeptidase 3
chr14_+_73237891 2.073 ENSMUST00000044405.6
Lpar6
lysophosphatidic acid receptor 6
chr2_+_4882204 2.009 ENSMUST00000115019.1
Sephs1
selenophosphate synthetase 1
chr12_-_17176888 1.929 ENSMUST00000170580.1
Kcnf1
potassium voltage-gated channel, subfamily F, member 1
chr1_-_184033998 1.920 ENSMUST00000050306.5
1700056E22Rik
RIKEN cDNA 1700056E22 gene
chr3_-_116129615 1.830 ENSMUST00000029574.8
Vcam1
vascular cell adhesion molecule 1
chr14_+_55853997 1.819 ENSMUST00000100529.3
Nynrin
NYN domain and retroviral integrase containing
chr6_+_124808885 1.819 ENSMUST00000143040.1
ENSMUST00000052727.4
ENSMUST00000130160.1
Spsb2


splA/ryanodine receptor domain and SOCS box containing 2


chr6_+_83137089 1.712 ENSMUST00000121093.1
ENSMUST00000087938.4
Rtkn

rhotekin

chr10_-_7792795 1.657 ENSMUST00000065124.1
6530403G13Rik
RIKEN cDNA 6530403G13 gene
chr1_-_118982551 1.651 ENSMUST00000159678.1
Gli2
GLI-Kruppel family member GLI2
chr11_+_62820469 1.649 ENSMUST00000108703.1
Trim16
tripartite motif-containing 16
chr11_+_117266216 1.626 ENSMUST00000019038.8
Sept9
septin 9
chr3_-_104818539 1.570 ENSMUST00000106774.1
ENSMUST00000106775.1
ENSMUST00000166979.1
ENSMUST00000136148.1
Mov10



Moloney leukemia virus 10



chr10_+_75589363 1.527 ENSMUST00000072217.2
Ggt5
gamma-glutamyltransferase 5
chr9_+_75775355 1.498 ENSMUST00000012281.7
Bmp5
bone morphogenetic protein 5
chr4_-_35845204 1.493 ENSMUST00000164772.1
ENSMUST00000065173.2
Lingo2

leucine rich repeat and Ig domain containing 2

chr1_-_167285110 1.488 ENSMUST00000027839.8
Uck2
uridine-cytidine kinase 2
chr17_-_32388885 1.488 ENSMUST00000087703.5
ENSMUST00000170603.1
Wiz

widely-interspaced zinc finger motifs

chr4_+_128654686 1.395 ENSMUST00000030588.6
ENSMUST00000136377.1
Phc2

polyhomeotic-like 2 (Drosophila)

chr6_+_50110837 1.359 ENSMUST00000167628.1
Mpp6
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
chr12_+_55598917 1.316 ENSMUST00000051857.3
Insm2
insulinoma-associated 2
chr6_-_99028874 1.147 ENSMUST00000154163.2
Foxp1
forkhead box P1
chr6_-_99028251 1.142 ENSMUST00000177437.1
ENSMUST00000177229.1
ENSMUST00000113321.1
ENSMUST00000124058.1
Foxp1



forkhead box P1



chr15_-_64382736 1.136 ENSMUST00000176384.1
ENSMUST00000175799.1
Asap1

ArfGAP with SH3 domain, ankyrin repeat and PH domain1

chr11_-_109472611 1.068 ENSMUST00000168740.1
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr11_-_102819663 1.058 ENSMUST00000092567.4
Gjc1
gap junction protein, gamma 1
chr2_-_84743655 1.049 ENSMUST00000181711.1
Gm19426
predicted gene, 19426
chr15_-_64382908 1.021 ENSMUST00000177374.1
ENSMUST00000023008.9
ENSMUST00000110115.2
ENSMUST00000110114.3
Asap1



ArfGAP with SH3 domain, ankyrin repeat and PH domain1



chr14_-_70627008 0.998 ENSMUST00000110984.2
Dmtn
dematin actin binding protein
chr8_-_115707778 0.975 ENSMUST00000109104.1
Maf
avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog
chr3_+_90072641 0.973 ENSMUST00000121503.1
ENSMUST00000119570.1
ENSMUST00000062193.9
Tpm3


tropomyosin 3, gamma


chr5_-_24351604 0.932 ENSMUST00000036092.7
Kcnh2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr9_+_44334685 0.918 ENSMUST00000052686.2
H2afx
H2A histone family, member X
chr9_+_21165714 0.917 ENSMUST00000039413.8
Pde4a
phosphodiesterase 4A, cAMP specific
chr18_+_56432116 0.903 ENSMUST00000070166.5
Gramd3
GRAM domain containing 3
chr7_+_128237357 0.885 ENSMUST00000044660.5
Armc5
armadillo repeat containing 5
chr7_-_127615208 0.847 ENSMUST00000122066.1
Zfp629
zinc finger protein 629
chr11_+_23666479 0.837 ENSMUST00000143117.1
Pus10
pseudouridylate synthase 10
chr7_-_4164796 0.822 ENSMUST00000076831.6
Cdc42ep5
CDC42 effector protein (Rho GTPase binding) 5
chr3_+_107595031 0.700 ENSMUST00000014747.1
Alx3
aristaless-like homeobox 3
chr7_-_4164442 0.699 ENSMUST00000140410.1
ENSMUST00000143825.1
Cdc42ep5

CDC42 effector protein (Rho GTPase binding) 5

chr4_+_109343029 0.572 ENSMUST00000030281.5
Eps15
epidermal growth factor receptor pathway substrate 15
chr3_+_127791374 0.566 ENSMUST00000171621.1
Tifa
TRAF-interacting protein with forkhead-associated domain
chr7_-_127615226 0.546 ENSMUST00000084564.3
Zfp629
zinc finger protein 629
chr10_+_19591949 0.538 ENSMUST00000020188.6
Ifngr1
interferon gamma receptor 1
chr11_+_108920342 0.456 ENSMUST00000052915.7
Axin2
axin2
chr19_+_55898553 0.444 ENSMUST00000148666.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chrX_+_110814390 0.417 ENSMUST00000078229.3
Pou3f4
POU domain, class 3, transcription factor 4
chr17_+_69383319 0.375 ENSMUST00000062369.7
Zbtb14
zinc finger and BTB domain containing 14
chr6_-_39557830 0.369 ENSMUST00000036877.3
ENSMUST00000154149.1
Dennd2a

DENN/MADD domain containing 2A

chr5_-_124354671 0.364 ENSMUST00000031341.4
Cdk2ap1
CDK2 (cyclin-dependent kinase 2)-associated protein 1
chr11_-_23665862 0.334 ENSMUST00000020523.3
Pex13
peroxisomal biogenesis factor 13
chr2_+_3118407 0.325 ENSMUST00000091505.4
Fam171a1
family with sequence similarity 171, member A1
chr2_-_84886692 0.306 ENSMUST00000054514.5
ENSMUST00000151799.1
Rtn4rl2

reticulon 4 receptor-like 2

chr2_+_3118335 0.289 ENSMUST00000115099.2
Fam171a1
family with sequence similarity 171, member A1
chr17_+_69383024 0.261 ENSMUST00000112674.1
Zbtb14
zinc finger and BTB domain containing 14
chr3_-_89338005 0.257 ENSMUST00000029674.7
Efna4
ephrin A4
chr9_+_108854024 0.233 ENSMUST00000098376.3
Slc26a6
solute carrier family 26, member 6
chr5_-_136883115 0.229 ENSMUST00000057497.6
ENSMUST00000111103.1
Col26a1

collagen, type XXVI, alpha 1

chr11_+_23666007 0.223 ENSMUST00000058163.4
Pus10
pseudouridylate synthase 10
chrX_+_159459125 0.206 ENSMUST00000043151.5
ENSMUST00000112470.1
ENSMUST00000156172.1
Map7d2


MAP7 domain containing 2


chr14_-_54653616 0.203 ENSMUST00000126166.1
ENSMUST00000141453.1
ENSMUST00000150371.1
ENSMUST00000123875.1
ENSMUST00000022794.7
ENSMUST00000148754.3
Acin1





apoptotic chromatin condensation inducer 1





chr3_-_79145875 0.168 ENSMUST00000118340.1
Rapgef2
Rap guanine nucleotide exchange factor (GEF) 2
chr2_-_32424005 0.165 ENSMUST00000113307.2
Slc25a25
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25
chr1_-_45503282 0.146 ENSMUST00000086430.4
Col5a2
collagen, type V, alpha 2
chr15_-_76199835 0.145 ENSMUST00000054449.7
ENSMUST00000169714.1
ENSMUST00000165453.1
Plec


plectin


chr16_-_36666067 0.140 ENSMUST00000089620.4
Cd86
CD86 antigen
chr7_-_128237984 0.136 ENSMUST00000078816.3
9130023H24Rik
RIKEN cDNA 9130023H24 gene
chr9_-_67539392 0.108 ENSMUST00000039662.8
Tln2
talin 2
chr10_+_128225830 0.087 ENSMUST00000026455.7
Mip
major intrinsic protein of eye lens fiber
chr5_+_65131184 0.086 ENSMUST00000031089.5
ENSMUST00000101191.3
Klhl5

kelch-like 5

chr1_+_134037490 0.078 ENSMUST00000162779.1
Fmod
fibromodulin
chr19_-_30549516 0.078 ENSMUST00000025803.8
Dkk1
dickkopf homolog 1 (Xenopus laevis)
chr16_-_29541483 0.067 ENSMUST00000057018.8
ENSMUST00000182627.1
Atp13a4

ATPase type 13A4

chr6_-_54593139 0.063 ENSMUST00000046520.6
Fkbp14
FK506 binding protein 14
chr11_-_109473220 0.047 ENSMUST00000070872.6
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr2_-_125723387 0.031 ENSMUST00000042246.7
Shc4
SHC (Src homology 2 domain containing) family, member 4
chr1_-_156718989 0.025 ENSMUST00000122424.1
Fam20b
family with sequence similarity 20, member B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 10.0 GO:0090274 positive regulation of somatostatin secretion(GO:0090274)
2.2 6.6 GO:0021557 oculomotor nerve development(GO:0021557)
1.1 15.6 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
1.0 3.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
1.0 3.0 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
1.0 2.9 GO:0097350 neutrophil clearance(GO:0097350)
0.7 3.6 GO:0035262 gonad morphogenesis(GO:0035262)
0.6 3.2 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.5 2.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.5 1.5 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.4 2.2 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.4 1.7 GO:0060032 notochord regression(GO:0060032)
0.4 1.5 GO:0006751 glutathione catabolic process(GO:0006751)
0.4 1.5 GO:0021502 neural fold elevation formation(GO:0021502)
0.4 1.1 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.3 1.0 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.2 2.3 GO:0061470 interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619)
0.2 1.8 GO:0015074 DNA integration(GO:0015074)
0.2 3.6 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.2 1.8 GO:0061032 visceral serous pericardium development(GO:0061032)
0.2 0.9 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.2 0.5 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.1 1.5 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1 1.6 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.1 1.5 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 1.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.1 2.1 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.1 0.2 GO:0035672 transepithelial chloride transport(GO:0030321) oligopeptide transmembrane transport(GO:0035672)
0.1 0.3 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 1.6 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 0.4 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.1 0.6 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.1 0.4 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 1.6 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.1 GO:1903224 regulation of endodermal cell differentiation(GO:1903224)
0.0 0.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 2.1 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.7 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.0 6.4 GO:0043524 negative regulation of neuron apoptotic process(GO:0043524)
0.0 0.1 GO:0002667 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.0 0.9 GO:0007608 sensory perception of smell(GO:0007608)
0.0 1.0 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.3 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.6 GO:0003170 heart valve development(GO:0003170)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.4 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.2 GO:0014823 response to activity(GO:0014823)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 11.6 GO:0032809 neuronal cell body membrane(GO:0032809)
0.2 1.0 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.2 0.9 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 1.7 GO:0097542 ciliary tip(GO:0097542)
0.1 8.0 GO:0005882 intermediate filament(GO:0005882)
0.1 2.9 GO:0043657 host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657)
0.1 5.0 GO:0002102 podosome(GO:0002102)
0.1 1.6 GO:0031105 septin complex(GO:0031105)
0.1 1.1 GO:0005922 connexon complex(GO:0005922)
0.1 1.4 GO:0035102 PRC1 complex(GO:0035102)
0.1 10.0 GO:0043195 terminal bouton(GO:0043195)
0.1 0.6 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 3.4 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 0.9 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.4 GO:0071664 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 2.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 3.4 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0061574 ASAP complex(GO:0061574)
0.0 3.7 GO:0001650 fibrillar center(GO:0001650)
0.0 1.6 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 1.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.6 GO:0016235 aggresome(GO:0016235)
0.0 0.2 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.3 GO:0005779 integral component of peroxisomal membrane(GO:0005779)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
1.0 9.0 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.5 1.6 GO:0019966 interleukin-1 binding(GO:0019966)
0.5 1.8 GO:0008131 primary amine oxidase activity(GO:0008131)
0.4 15.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.4 9.7 GO:0008432 JUN kinase binding(GO:0008432)
0.4 1.1 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.4 2.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.3 1.5 GO:0004849 uridine kinase activity(GO:0004849)
0.3 2.9 GO:0032036 myosin heavy chain binding(GO:0032036)
0.3 3.1 GO:0035014 retinoic acid binding(GO:0001972) phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.2 1.5 GO:0008242 omega peptidase activity(GO:0008242)
0.2 1.7 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.2 3.0 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.2 10.0 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.2 0.9 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.2 2.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 2.1 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.1 1.5 GO:0070700 BMP receptor binding(GO:0070700)
0.1 1.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 1.1 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.2 GO:0015563 uptake transmembrane transporter activity(GO:0015563)
0.0 2.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 1.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.3 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 1.1 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.4 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 3.2 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.4 GO:0070016 gamma-catenin binding(GO:0045295) armadillo repeat domain binding(GO:0070016)
0.0 2.3 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 1.0 GO:0043621 protein self-association(GO:0043621)
0.0 0.2 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.9 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.4 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.5 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.2 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.6 GO:0031593 polyubiquitin binding(GO:0031593)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 9.5 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 1.8 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 3.1 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 3.1 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 2.2 PID_ARF_3PATHWAY Arf1 pathway
0.1 3.2 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.1 3.4 PID_RHOA_PATHWAY RhoA signaling pathway
0.1 1.7 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.5 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.0 0.9 PID_ATM_PATHWAY ATM pathway
0.0 1.0 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.5 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.0 0.6 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.2 15.6 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.2 5.5 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 10.0 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 1.1 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.1 1.8 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 2.9 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 1.5 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.1 1.5 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.1 1.6 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 0.9 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 3.1 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.5 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.0 1.0 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.1 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.6 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.1 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins