Motif ID: Gata5

Z-value: 0.793


Transcription factors associated with Gata5:

Gene SymbolEntrez IDGene Name
Gata5 ENSMUSG00000015627.5 Gata5



Activity profile for motif Gata5.

activity profile for motif Gata5


Sorted Z-values histogram for motif Gata5

Sorted Z-values for motif Gata5



Network of associatons between targets according to the STRING database.



First level regulatory network of Gata5

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_103853199 10.710 ENSMUST00000033229.3
Hbb-y
hemoglobin Y, beta-like embryonic chain
chr11_+_32276893 6.174 ENSMUST00000145569.1
Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr11_+_32276400 6.012 ENSMUST00000020531.2
Hba-x
hemoglobin X, alpha-like embryonic chain in Hba complex
chr16_-_44558879 3.145 ENSMUST00000114634.1
Boc
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr14_+_75455957 2.848 ENSMUST00000164848.1
Siah3
seven in absentia homolog 3 (Drosophila)
chr10_-_26078987 2.308 ENSMUST00000066049.6
Tmem200a
transmembrane protein 200A
chr7_-_70366735 2.293 ENSMUST00000089565.5
Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr8_+_45658666 2.292 ENSMUST00000134675.1
ENSMUST00000139869.1
ENSMUST00000126067.1
Sorbs2


sorbin and SH3 domain containing 2


chr11_+_95337012 1.966 ENSMUST00000037502.6
Fam117a
family with sequence similarity 117, member A
chr10_-_92162753 1.773 ENSMUST00000182197.1
Rmst
rhabdomyosarcoma 2 associated transcript (non-coding RNA)
chr7_-_99238564 1.760 ENSMUST00000064231.7
Mogat2
monoacylglycerol O-acyltransferase 2
chr8_+_45658273 1.760 ENSMUST00000153798.1
Sorbs2
sorbin and SH3 domain containing 2
chr14_+_70457447 1.421 ENSMUST00000003561.3
Phyhip
phytanoyl-CoA hydroxylase interacting protein
chr9_-_58201705 1.332 ENSMUST00000163200.1
ENSMUST00000165276.1
Islr2

immunoglobulin superfamily containing leucine-rich repeat 2

chr3_+_146121655 1.213 ENSMUST00000039450.4
Mcoln3
mucolipin 3
chr13_+_108316332 1.206 ENSMUST00000051594.5
Depdc1b
DEP domain containing 1B
chr8_+_67494843 1.175 ENSMUST00000093470.5
ENSMUST00000163856.1
Nat2

N-acetyltransferase 2 (arylamine N-acetyltransferase)

chr5_+_93093428 1.149 ENSMUST00000074733.7
Sept11
septin 11
chrX_-_8193387 1.090 ENSMUST00000143223.1
ENSMUST00000033509.8
Ebp

phenylalkylamine Ca2+ antagonist (emopamil) binding protein

chr2_-_79908428 0.987 ENSMUST00000102652.3
ENSMUST00000102651.3
Pde1a

phosphodiesterase 1A, calmodulin-dependent

chr13_+_108316395 0.941 ENSMUST00000171178.1
Depdc1b
DEP domain containing 1B
chr1_+_135232045 0.894 ENSMUST00000110798.3
Gm4204
predicted gene 4204
chr3_-_94886945 0.830 ENSMUST00000005923.6
Psmb4
proteasome (prosome, macropain) subunit, beta type 4
chr16_-_50432340 0.804 ENSMUST00000066037.6
ENSMUST00000089399.4
ENSMUST00000089404.3
ENSMUST00000114477.1
ENSMUST00000138166.1
Bbx




bobby sox homolog (Drosophila)




chr6_-_127109517 0.800 ENSMUST00000039913.8
9630033F20Rik
RIKEN cDNA 9630033F20 gene
chrM_+_5319 0.786 ENSMUST00000082402.1
mt-Co1
mitochondrially encoded cytochrome c oxidase I
chr5_+_42067960 0.781 ENSMUST00000087332.4
Gm16223
predicted gene 16223
chr11_-_109995775 0.780 ENSMUST00000020948.8
Abca8b
ATP-binding cassette, sub-family A (ABC1), member 8b
chr11_-_109995743 0.761 ENSMUST00000106669.2
Abca8b
ATP-binding cassette, sub-family A (ABC1), member 8b
chr11_+_32296489 0.720 ENSMUST00000093207.3
Hba-a2
hemoglobin alpha, adult chain 2
chr11_+_94936224 0.705 ENSMUST00000001547.7
Col1a1
collagen, type I, alpha 1
chr2_-_79908389 0.677 ENSMUST00000090756.4
Pde1a
phosphodiesterase 1A, calmodulin-dependent
chr3_-_146839365 0.659 ENSMUST00000084614.3
Gm10288
predicted gene 10288
chr2_+_84980458 0.634 ENSMUST00000028467.5
Prg2
proteoglycan 2, bone marrow
chr6_-_92706145 0.595 ENSMUST00000032093.5
Prickle2
prickle homolog 2 (Drosophila)
chr3_+_4211716 0.589 ENSMUST00000170943.1
Gm8775
predicted gene 8775
chr12_-_108893197 0.587 ENSMUST00000161154.1
ENSMUST00000161410.1
Wars

tryptophanyl-tRNA synthetase

chr1_+_143640664 0.575 ENSMUST00000038252.2
B3galt2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr7_+_126862431 0.556 ENSMUST00000132808.1
Hirip3
HIRA interacting protein 3
chr15_-_103251465 0.555 ENSMUST00000133600.1
ENSMUST00000134554.1
ENSMUST00000156927.1
ENSMUST00000149111.1
ENSMUST00000132836.1
Nfe2




nuclear factor, erythroid derived 2




chr7_-_4630473 0.553 ENSMUST00000055085.6
Tmem86b
transmembrane protein 86B
chr2_+_85037212 0.533 ENSMUST00000077798.6
Ssrp1
structure specific recognition protein 1
chr10_+_61648552 0.531 ENSMUST00000020286.6
Ppa1
pyrophosphatase (inorganic) 1
chr13_-_107414742 0.519 ENSMUST00000061241.6
Apoo-ps
apolipoprotein O, pseudogene
chr4_-_59438633 0.494 ENSMUST00000040166.7
ENSMUST00000107544.1
Susd1

sushi domain containing 1

chr7_+_67647405 0.479 ENSMUST00000032774.8
ENSMUST00000107471.1
Ttc23

tetratricopeptide repeat domain 23

chr15_-_50890396 0.466 ENSMUST00000185183.1
Trps1
trichorhinophalangeal syndrome I (human)
chr11_+_97030130 0.458 ENSMUST00000153482.1
Scrn2
secernin 2
chr7_-_23947237 0.456 ENSMUST00000086013.2
Gm10175
predicted gene 10175
chr5_+_88583527 0.448 ENSMUST00000031229.6
Rufy3
RUN and FYVE domain containing 3
chr16_-_50330987 0.439 ENSMUST00000114488.1
Bbx
bobby sox homolog (Drosophila)
chr11_+_58948890 0.432 ENSMUST00000078267.3
Hist3h2ba
histone cluster 3, H2ba
chr2_+_71786923 0.425 ENSMUST00000112101.1
ENSMUST00000028522.3
Itga6

integrin alpha 6

chr6_-_119330723 0.424 ENSMUST00000068351.7
Lrtm2
leucine-rich repeats and transmembrane domains 2
chr3_+_142594847 0.414 ENSMUST00000029936.4
Gbp2b
guanylate binding protein 2b
chr10_+_45577811 0.413 ENSMUST00000037044.6
Hace1
HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1
chr6_-_119330668 0.409 ENSMUST00000112756.1
Lrtm2
leucine-rich repeats and transmembrane domains 2
chr12_-_27342696 0.392 ENSMUST00000079063.5
Sox11
SRY-box containing gene 11
chr12_+_4817545 0.390 ENSMUST00000046207.7
0610009D07Rik
RIKEN cDNA 0610009D07 gene
chr6_+_137735078 0.384 ENSMUST00000064910.6
Strap
serine/threonine kinase receptor associated protein
chr2_+_85037448 0.384 ENSMUST00000168266.1
ENSMUST00000130729.1
Ssrp1

structure specific recognition protein 1

chr8_+_53511695 0.379 ENSMUST00000033920.4
Aga
aspartylglucosaminidase
chr1_+_71652837 0.372 ENSMUST00000097699.2
Apol7d
apolipoprotein L 7d
chr7_-_141434532 0.365 ENSMUST00000133021.1
ENSMUST00000106007.3
ENSMUST00000150026.1
ENSMUST00000133206.2
Slc25a22



solute carrier family 25 (mitochondrial carrier, glutamate), member 22



chr16_-_34095983 0.362 ENSMUST00000114973.1
ENSMUST00000114964.1
Kalrn

kalirin, RhoGEF kinase

chr11_-_101551837 0.348 ENSMUST00000017290.4
Brca1
breast cancer 1
chr19_-_43524462 0.344 ENSMUST00000026196.7
Got1
glutamate oxaloacetate transaminase 1, soluble
chr17_-_46645128 0.343 ENSMUST00000003642.6
Klc4
kinesin light chain 4
chr9_+_96895617 0.340 ENSMUST00000071781.6
Gm10123
predicted pseudogene 10123
chr12_-_113307912 0.318 ENSMUST00000103418.1
Ighg2b
immunoglobulin heavy constant gamma 2B
chr1_+_172376528 0.317 ENSMUST00000052455.2
Pigm
phosphatidylinositol glycan anchor biosynthesis, class M
chr9_-_50528641 0.307 ENSMUST00000034570.5
Pts
6-pyruvoyl-tetrahydropterin synthase
chr1_-_85270543 0.304 ENSMUST00000093506.5
ENSMUST00000064341.8
C130026I21Rik

RIKEN cDNA C130026I21 gene

chr15_-_95528702 0.301 ENSMUST00000166170.1
Nell2
NEL-like 2
chr9_+_75037838 0.296 ENSMUST00000169188.1
Arpp19
cAMP-regulated phosphoprotein 19
chr6_+_81923645 0.293 ENSMUST00000043195.4
Gcfc2
GC-rich sequence DNA binding factor 2
chr6_+_34384218 0.292 ENSMUST00000038383.7
ENSMUST00000115051.1
Akr1b10

aldo-keto reductase family 1, member B10 (aldose reductase)

chr7_+_27731373 0.273 ENSMUST00000108336.1
Zfp60
zinc finger protein 60
chr4_-_3973581 0.273 ENSMUST00000089430.4
Gm11808
predicted gene 11808
chr15_+_6299797 0.269 ENSMUST00000159046.1
ENSMUST00000161040.1
Dab2

disabled 2, mitogen-responsive phosphoprotein

chr4_+_126677630 0.266 ENSMUST00000030642.2
Psmb2
proteasome (prosome, macropain) subunit, beta type 2
chr17_+_40811089 0.254 ENSMUST00000024721.7
Rhag
Rhesus blood group-associated A glycoprotein
chr4_+_149545102 0.254 ENSMUST00000105692.1
Ctnnbip1
catenin beta interacting protein 1
chr2_+_167062934 0.253 ENSMUST00000125674.1
1500012F01Rik
RIKEN cDNA 1500012F01 gene
chr1_-_156032948 0.251 ENSMUST00000136397.1
Tor1aip1
torsin A interacting protein 1
chr7_-_126861828 0.245 ENSMUST00000106343.1
Ino80e
INO80 complex subunit E
chr13_+_13954614 0.242 ENSMUST00000099747.3
B3galnt2
UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 2
chr4_+_6191093 0.230 ENSMUST00000029907.5
Ubxn2b
UBX domain protein 2B
chrX_-_134111852 0.219 ENSMUST00000033610.6
Nox1
NADPH oxidase 1
chr6_+_135011609 0.218 ENSMUST00000032326.4
ENSMUST00000130851.1
ENSMUST00000154558.1
Ddx47


DEAD (Asp-Glu-Ala-Asp) box polypeptide 47


chrX_+_52988119 0.212 ENSMUST00000026723.8
Hprt
hypoxanthine guanine phosphoribosyl transferase
chr6_+_122707489 0.209 ENSMUST00000112581.1
ENSMUST00000112580.1
ENSMUST00000012540.4
Nanog


Nanog homeobox


chr15_+_102406143 0.207 ENSMUST00000170884.1
ENSMUST00000165924.1
ENSMUST00000163709.1
ENSMUST00000001326.6
Sp1



trans-acting transcription factor 1



chr15_-_86186136 0.207 ENSMUST00000044332.9
Cerk
ceramide kinase
chrX_-_139998519 0.206 ENSMUST00000113007.1
ENSMUST00000033810.7
ENSMUST00000113011.2
ENSMUST00000087400.5
Rbm41



RNA binding motif protein 41



chr3_+_89136572 0.202 ENSMUST00000107482.3
ENSMUST00000127058.1
Pklr

pyruvate kinase liver and red blood cell

chr7_-_126861648 0.202 ENSMUST00000129812.1
ENSMUST00000106342.1
Ino80e

INO80 complex subunit E

chr11_+_97029925 0.193 ENSMUST00000021249.4
Scrn2
secernin 2
chr14_-_63543931 0.192 ENSMUST00000058679.5
Mtmr9
myotubularin related protein 9
chr2_-_37359274 0.189 ENSMUST00000009174.8
Pdcl
phosducin-like
chr10_+_79988584 0.187 ENSMUST00000004784.4
ENSMUST00000105374.1
Cnn2

calponin 2

chr8_-_125898291 0.186 ENSMUST00000047239.6
Pcnxl2
pecanex-like 2 (Drosophila)
chr14_+_101653967 0.181 ENSMUST00000002289.6
Uchl3
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr13_-_67332525 0.171 ENSMUST00000168892.1
ENSMUST00000109735.2
Zfp595

zinc finger protein 595

chr2_+_26583858 0.165 ENSMUST00000100290.5
ENSMUST00000102907.5
Egfl7

EGF-like domain 7

chr4_+_135855707 0.159 ENSMUST00000105853.3
ENSMUST00000097844.2
ENSMUST00000102544.2
ENSMUST00000126641.1
Srsf10



serine/arginine-rich splicing factor 10



chr10_-_116950366 0.136 ENSMUST00000020375.6
Rab3ip
RAB3A interacting protein
chr2_+_152427639 0.127 ENSMUST00000128737.1
6820408C15Rik
RIKEN cDNA 6820408C15 gene
chr2_-_153632679 0.125 ENSMUST00000109782.1
Commd7
COMM domain containing 7
chr5_-_73191848 0.122 ENSMUST00000176910.1
Fryl
furry homolog-like (Drosophila)
chr15_+_100154379 0.116 ENSMUST00000023768.6
ENSMUST00000108971.2
Dip2b

DIP2 disco-interacting protein 2 homolog B (Drosophila)

chr15_-_76069681 0.106 ENSMUST00000002603.5
ENSMUST00000063747.5
Scrib

scribbled homolog (Drosophila)

chr4_+_103143052 0.099 ENSMUST00000106855.1
Mier1
mesoderm induction early response 1 homolog (Xenopus laevis
chr2_-_37359235 0.096 ENSMUST00000112940.1
Pdcl
phosducin-like
chr2_+_11642786 0.094 ENSMUST00000028111.4
Il2ra
interleukin 2 receptor, alpha chain
chr6_-_122856151 0.093 ENSMUST00000042081.8
C3ar1
complement component 3a receptor 1
chr19_-_38819156 0.088 ENSMUST00000025963.7
Noc3l
nucleolar complex associated 3 homolog (S. cerevisiae)
chr6_+_136954521 0.082 ENSMUST00000137768.1
Pde6h
phosphodiesterase 6H, cGMP-specific, cone, gamma
chr3_-_97610156 0.079 ENSMUST00000029730.4
Chd1l
chromodomain helicase DNA binding protein 1-like
chr16_+_58670208 0.077 ENSMUST00000060077.5
Cpox
coproporphyrinogen oxidase
chr2_+_154656959 0.077 ENSMUST00000044277.9
Chmp4b
charged multivesicular body protein 4B
chr3_+_95427575 0.074 ENSMUST00000181809.1
Gm4349
predicted gene 4349
chr11_-_45955183 0.070 ENSMUST00000109254.1
Thg1l
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr6_-_34317442 0.069 ENSMUST00000154655.1
ENSMUST00000102980.4
Akr1b3

aldo-keto reductase family 1, member B3 (aldose reductase)

chr3_-_151762906 0.062 ENSMUST00000046739.4
Ifi44l
interferon-induced protein 44 like
chr12_+_95692212 0.062 ENSMUST00000057324.3
Flrt2
fibronectin leucine rich transmembrane protein 2
chr4_+_12140263 0.054 ENSMUST00000050069.2
ENSMUST00000069128.7
Rbm12b1

RNA binding motif protein 12 B1

chr16_+_36934976 0.047 ENSMUST00000023531.8
Hcls1
hematopoietic cell specific Lyn substrate 1
chr17_+_48346465 0.046 ENSMUST00000113237.3
Trem2
triggering receptor expressed on myeloid cells 2
chr1_-_33814516 0.036 ENSMUST00000044455.5
ENSMUST00000115167.1
Zfp451

zinc finger protein 451

chr2_-_25224653 0.033 ENSMUST00000043584.4
Tubb4b
tubulin, beta 4B class IVB
chr7_-_15627876 0.024 ENSMUST00000086122.3
ENSMUST00000174443.1
Obox3

oocyte specific homeobox 3

chr17_+_45523416 0.022 ENSMUST00000113547.1
Tcte1
t-complex-associated testis expressed 1
chrX_-_37104523 0.017 ENSMUST00000130324.1
Upf3b
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr2_+_31887262 0.012 ENSMUST00000138325.1
ENSMUST00000028187.6
Lamc3

laminin gamma 3

chr15_-_60824942 0.006 ENSMUST00000100635.3
Fam84b
family with sequence similarity 84, member B
chr3_+_55140033 0.001 ENSMUST00000118963.2
ENSMUST00000061099.7
ENSMUST00000153009.1
Ccdc169


coiled-coil domain containing 169



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 22.9 GO:0015671 oxygen transport(GO:0015671)
0.6 1.8 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.6 2.8 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.5 2.3 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.2 0.6 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.2 0.6 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 0.4 GO:0019401 alditol biosynthetic process(GO:0019401)
0.1 0.4 GO:0060023 soft palate development(GO:0060023)
0.1 3.1 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.1 0.3 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.1 0.8 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 0.7 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 1.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.3 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.1 4.0 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.3 GO:0016068 regulation of type I hypersensitivity(GO:0001810) positive regulation of type I hypersensitivity(GO:0001812) type I hypersensitivity(GO:0016068)
0.1 0.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.2 GO:1902605 heterotrimeric G-protein complex assembly(GO:1902605)
0.1 0.2 GO:0046098 purine nucleobase salvage(GO:0043096) guanine metabolic process(GO:0046098) hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.1 0.4 GO:0035878 nail development(GO:0035878)
0.1 0.2 GO:1903225 regulation of endodermal cell fate specification(GO:0042663) negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.6 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.6 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.1 0.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.6 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.1 0.2 GO:0072592 integrin biosynthetic process(GO:0045112) regulation of integrin biosynthetic process(GO:0045113) oxygen metabolic process(GO:0072592)
0.1 0.3 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.4 GO:0061368 maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.3 GO:0032346 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349) leading edge cell differentiation(GO:0035026) regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.0 0.6 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.3 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.1 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.0 0.2 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.2 GO:0070814 hydrogen sulfide biosynthetic process(GO:0070814)
0.0 0.3 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.4 GO:0006517 protein deglycosylation(GO:0006517)
0.0 1.8 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.3 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.4 GO:0044406 adhesion of symbiont to host(GO:0044406)
0.0 0.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.0 GO:0032499 detection of peptidoglycan(GO:0032499)
0.0 1.1 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.5 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.7 GO:0048821 erythrocyte development(GO:0048821)
0.0 0.1 GO:0090527 actin filament reorganization(GO:0090527)
0.0 2.1 GO:0030177 positive regulation of Wnt signaling pathway(GO:0030177)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.1 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.0 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
0.0 0.3 GO:0015813 L-glutamate transport(GO:0015813)
0.0 0.3 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.2 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.1 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 22.5 GO:0005833 hemoglobin complex(GO:0005833)
0.2 0.7 GO:0005584 collagen type I trimer(GO:0005584)
0.1 0.3 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.1 0.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.3 GO:0070531 BRCA1-A complex(GO:0070531)
0.1 0.8 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.1 3.1 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.4 GO:0071437 invadopodium(GO:0071437)
0.0 1.1 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.4 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.4 GO:0032797 SMN complex(GO:0032797)
0.0 0.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.4 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.0 0.4 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 1.3 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 22.9 GO:0005344 oxygen transporter activity(GO:0005344)
0.6 1.8 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.4 1.1 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.2 1.7 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 0.6 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.2 2.3 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.6 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 0.4 GO:0019002 GMP binding(GO:0019002)
0.1 0.5 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 0.3 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.1 0.6 GO:0016803 ether hydrolase activity(GO:0016803)
0.1 0.4 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1 0.4 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.2 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 0.2 GO:0001729 ceramide kinase activity(GO:0001729)
0.1 0.2 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.9 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.2 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.8 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.3 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.1 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.3 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.3 GO:0022842 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.0 0.6 GO:0050699 WW domain binding(GO:0050699)
0.0 0.3 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.7 GO:0020037 heme binding(GO:0020037)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 1.2 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 1.4 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.1 2.8 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 0.4 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.7 PID_LYMPH_ANGIOGENESIS_PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.6 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.9 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.1 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES Genes related to PIP3 signaling in cardiac myocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 1.7 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 1.1 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.1 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.3 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.0 0.9 REACTOME_ELONGATION_ARREST_AND_RECOVERY Genes involved in Elongation arrest and recovery
0.0 2.3 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.3 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.3 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.1 REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.3 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.3 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.3 REACTOME_KINESINS Genes involved in Kinesins
0.0 2.3 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.4 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.3 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)