Motif ID: Tlx2
Z-value: 0.715

Transcription factors associated with Tlx2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Tlx2 | ENSMUSG00000068327.3 | Tlx2 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.2 | 4.8 | GO:0046552 | eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552) |
0.8 | 7.2 | GO:1902715 | positive regulation of interferon-gamma secretion(GO:1902715) |
0.6 | 1.9 | GO:1903048 | regulation of acetylcholine-gated cation channel activity(GO:1903048) |
0.6 | 1.9 | GO:2000435 | regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435) |
0.6 | 1.7 | GO:0090187 | zymogen granule exocytosis(GO:0070625) positive regulation of pancreatic juice secretion(GO:0090187) |
0.5 | 1.6 | GO:0061357 | Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356) positive regulation of Wnt protein secretion(GO:0061357) |
0.5 | 2.0 | GO:2000974 | negative regulation of pro-B cell differentiation(GO:2000974) |
0.5 | 1.4 | GO:0035519 | protein K29-linked ubiquitination(GO:0035519) |
0.5 | 0.5 | GO:0060455 | negative regulation of gastric acid secretion(GO:0060455) |
0.5 | 1.4 | GO:0006566 | threonine metabolic process(GO:0006566) |
0.4 | 1.3 | GO:0060392 | negative regulation of SMAD protein import into nucleus(GO:0060392) |
0.4 | 1.2 | GO:0021529 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) |
0.4 | 1.5 | GO:0043973 | histone H3-K4 acetylation(GO:0043973) |
0.4 | 1.1 | GO:1902713 | regulation of interferon-gamma secretion(GO:1902713) |
0.4 | 2.1 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
0.4 | 1.1 | GO:0061300 | cerebellum vasculature development(GO:0061300) |
0.3 | 2.7 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
0.3 | 1.0 | GO:0018298 | protein-chromophore linkage(GO:0018298) |
0.3 | 0.9 | GO:1905203 | regulation of connective tissue replacement(GO:1905203) |
0.3 | 0.9 | GO:0031117 | positive regulation of microtubule depolymerization(GO:0031117) |
0.3 | 1.1 | GO:0032914 | positive regulation of transforming growth factor beta1 production(GO:0032914) |
0.3 | 2.1 | GO:0046645 | positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645) positive regulation of uterine smooth muscle contraction(GO:0070474) |
0.2 | 0.7 | GO:0033566 | gamma-tubulin complex localization(GO:0033566) |
0.2 | 0.7 | GO:0006296 | base-excision repair, AP site formation(GO:0006285) nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296) |
0.2 | 1.1 | GO:0060591 | chondroblast differentiation(GO:0060591) |
0.2 | 0.6 | GO:0021577 | hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) |
0.2 | 0.6 | GO:0030300 | regulation of intestinal cholesterol absorption(GO:0030300) |
0.2 | 1.0 | GO:0098706 | ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706) |
0.2 | 0.9 | GO:0045918 | negative regulation of cytolysis(GO:0045918) |
0.2 | 0.3 | GO:0034382 | chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) |
0.2 | 0.7 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) pyroptosis(GO:0070269) |
0.2 | 1.0 | GO:0002934 | desmosome organization(GO:0002934) |
0.2 | 0.6 | GO:0010511 | regulation of phosphatidylinositol biosynthetic process(GO:0010511) |
0.2 | 0.9 | GO:0060024 | rhythmic synaptic transmission(GO:0060024) |
0.2 | 0.5 | GO:0001803 | antibody-dependent cellular cytotoxicity(GO:0001788) type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805) |
0.2 | 0.5 | GO:0006434 | seryl-tRNA aminoacylation(GO:0006434) |
0.2 | 1.5 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
0.1 | 0.4 | GO:2000319 | negative regulation of T-helper 17 type immune response(GO:2000317) regulation of T-helper 17 cell differentiation(GO:2000319) negative regulation of T-helper 17 cell differentiation(GO:2000320) |
0.1 | 1.3 | GO:0007076 | mitotic chromosome condensation(GO:0007076) |
0.1 | 0.7 | GO:0007320 | insemination(GO:0007320) |
0.1 | 0.3 | GO:0071603 | endothelial cell-cell adhesion(GO:0071603) |
0.1 | 1.0 | GO:0007343 | egg activation(GO:0007343) |
0.1 | 0.6 | GO:0010510 | regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) |
0.1 | 0.6 | GO:0036518 | chemorepulsion of dopaminergic neuron axon(GO:0036518) |
0.1 | 0.4 | GO:0010752 | signal complex assembly(GO:0007172) regulation of cGMP-mediated signaling(GO:0010752) |
0.1 | 0.7 | GO:0032627 | interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) |
0.1 | 2.4 | GO:0009263 | deoxyribonucleotide biosynthetic process(GO:0009263) |
0.1 | 0.4 | GO:0001951 | intestinal D-glucose absorption(GO:0001951) terminal web assembly(GO:1902896) |
0.1 | 0.4 | GO:0046110 | xanthine metabolic process(GO:0046110) |
0.1 | 0.5 | GO:0014012 | peripheral nervous system axon regeneration(GO:0014012) |
0.1 | 0.4 | GO:0070889 | platelet alpha granule organization(GO:0070889) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) |
0.1 | 0.4 | GO:0007521 | muscle cell fate determination(GO:0007521) mammary placode formation(GO:0060596) |
0.1 | 1.4 | GO:0046512 | sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520) |
0.1 | 1.1 | GO:0032306 | regulation of prostaglandin secretion(GO:0032306) |
0.1 | 0.6 | GO:0018171 | peptidyl-cysteine oxidation(GO:0018171) |
0.1 | 0.5 | GO:0072592 | oxygen metabolic process(GO:0072592) |
0.1 | 0.5 | GO:0043654 | recognition of apoptotic cell(GO:0043654) |
0.1 | 1.1 | GO:0015838 | proline transport(GO:0015824) amino-acid betaine transport(GO:0015838) |
0.1 | 0.9 | GO:0071557 | histone H3-K27 demethylation(GO:0071557) |
0.1 | 1.1 | GO:0051256 | mitotic spindle midzone assembly(GO:0051256) |
0.1 | 1.9 | GO:2000574 | regulation of microtubule motor activity(GO:2000574) |
0.1 | 0.6 | GO:0097646 | calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647) |
0.1 | 0.4 | GO:0060745 | mammary gland branching involved in pregnancy(GO:0060745) |
0.1 | 1.1 | GO:0032525 | somite rostral/caudal axis specification(GO:0032525) |
0.1 | 0.5 | GO:0032489 | regulation of Cdc42 protein signal transduction(GO:0032489) |
0.1 | 0.5 | GO:0031580 | membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) |
0.1 | 1.1 | GO:0060501 | positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) |
0.1 | 0.3 | GO:2001160 | regulation of histone H3-K79 methylation(GO:2001160) |
0.1 | 0.5 | GO:2000074 | regulation of type B pancreatic cell development(GO:2000074) |
0.1 | 0.6 | GO:1990416 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416) |
0.1 | 0.6 | GO:0090400 | stress-induced premature senescence(GO:0090400) |
0.1 | 0.3 | GO:0072139 | glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of epithelial cell differentiation involved in kidney development(GO:2000698) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768) |
0.1 | 0.5 | GO:0006108 | malate metabolic process(GO:0006108) |
0.1 | 0.4 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
0.1 | 1.2 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
0.1 | 0.5 | GO:0016127 | cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127) |
0.1 | 0.3 | GO:2000383 | regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384) |
0.1 | 0.5 | GO:0097491 | trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287) |
0.1 | 0.5 | GO:1990504 | dense core granule exocytosis(GO:1990504) |
0.1 | 0.4 | GO:2001025 | positive regulation of response to drug(GO:2001025) |
0.1 | 0.2 | GO:0010641 | positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641) |
0.1 | 0.3 | GO:0090365 | regulation of mRNA modification(GO:0090365) |
0.1 | 0.2 | GO:2000987 | positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987) |
0.1 | 0.8 | GO:0006228 | UTP biosynthetic process(GO:0006228) |
0.1 | 1.3 | GO:0014049 | positive regulation of glutamate secretion(GO:0014049) |
0.1 | 0.8 | GO:0060347 | heart trabecula formation(GO:0060347) |
0.1 | 0.2 | GO:1902630 | regulation of membrane hyperpolarization(GO:1902630) |
0.1 | 0.7 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
0.1 | 0.3 | GO:0097211 | prolactin secretion(GO:0070459) response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211) |
0.1 | 1.3 | GO:0006346 | methylation-dependent chromatin silencing(GO:0006346) |
0.1 | 0.4 | GO:0007021 | tubulin complex assembly(GO:0007021) |
0.1 | 0.7 | GO:2000653 | regulation of genetic imprinting(GO:2000653) |
0.1 | 0.3 | GO:0002339 | B cell selection(GO:0002339) |
0.1 | 0.1 | GO:0002322 | B cell proliferation involved in immune response(GO:0002322) |
0.1 | 0.5 | GO:0002681 | somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153) |
0.1 | 0.8 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
0.1 | 0.1 | GO:0002408 | myeloid dendritic cell chemotaxis(GO:0002408) |
0.1 | 1.5 | GO:0045943 | positive regulation of transcription from RNA polymerase I promoter(GO:0045943) |
0.1 | 0.5 | GO:0006071 | glycerol metabolic process(GO:0006071) |
0.1 | 1.4 | GO:0008340 | determination of adult lifespan(GO:0008340) |
0.1 | 1.4 | GO:0009648 | photoperiodism(GO:0009648) |
0.1 | 0.1 | GO:0099527 | postsynapse to nucleus signaling pathway(GO:0099527) |
0.1 | 0.5 | GO:0030206 | chondroitin sulfate biosynthetic process(GO:0030206) |
0.1 | 0.3 | GO:0014816 | skeletal muscle satellite cell differentiation(GO:0014816) |
0.1 | 0.6 | GO:0002643 | regulation of tolerance induction(GO:0002643) |
0.1 | 0.7 | GO:0001516 | prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457) |
0.1 | 0.5 | GO:0043568 | positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568) |
0.1 | 0.9 | GO:0043552 | positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552) |
0.1 | 0.6 | GO:1904948 | midbrain dopaminergic neuron differentiation(GO:1904948) |
0.0 | 1.7 | GO:0050829 | defense response to Gram-negative bacterium(GO:0050829) |
0.0 | 0.1 | GO:0070844 | misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846) |
0.0 | 0.7 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
0.0 | 0.2 | GO:0010593 | negative regulation of lamellipodium assembly(GO:0010593) |
0.0 | 0.5 | GO:0071318 | cellular response to ATP(GO:0071318) |
0.0 | 0.3 | GO:0030263 | apoptotic chromosome condensation(GO:0030263) |
0.0 | 0.9 | GO:0014046 | dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059) |
0.0 | 0.3 | GO:0002862 | negative regulation of inflammatory response to antigenic stimulus(GO:0002862) |
0.0 | 0.4 | GO:0009404 | toxin metabolic process(GO:0009404) |
0.0 | 0.8 | GO:0032060 | bleb assembly(GO:0032060) |
0.0 | 0.3 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
0.0 | 0.2 | GO:0015744 | succinate transport(GO:0015744) |
0.0 | 0.4 | GO:0006348 | chromatin silencing at telomere(GO:0006348) |
0.0 | 0.3 | GO:0015074 | DNA integration(GO:0015074) |
0.0 | 1.4 | GO:0007099 | centriole replication(GO:0007099) |
0.0 | 1.0 | GO:0051894 | positive regulation of focal adhesion assembly(GO:0051894) |
0.0 | 1.7 | GO:0007218 | neuropeptide signaling pathway(GO:0007218) |
0.0 | 1.7 | GO:0033119 | negative regulation of RNA splicing(GO:0033119) |
0.0 | 0.3 | GO:0046085 | adenosine metabolic process(GO:0046085) |
0.0 | 0.2 | GO:0006680 | glucosylceramide catabolic process(GO:0006680) |
0.0 | 0.4 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
0.0 | 0.3 | GO:0006086 | acetyl-CoA biosynthetic process from pyruvate(GO:0006086) |
0.0 | 0.1 | GO:0032382 | positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373) |
0.0 | 0.3 | GO:1900364 | negative regulation of mRNA polyadenylation(GO:1900364) |
0.0 | 0.6 | GO:0007220 | Notch receptor processing(GO:0007220) |
0.0 | 0.1 | GO:0051316 | attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation(GO:0051316) |
0.0 | 0.2 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) |
0.0 | 0.2 | GO:0007197 | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207) |
0.0 | 0.3 | GO:1904637 | response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637) |
0.0 | 2.2 | GO:0032543 | mitochondrial translation(GO:0032543) |
0.0 | 0.4 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
0.0 | 0.2 | GO:0060343 | trabecula formation(GO:0060343) |
0.0 | 0.2 | GO:0030174 | regulation of DNA-dependent DNA replication initiation(GO:0030174) |
0.0 | 0.1 | GO:0036233 | glycine import(GO:0036233) |
0.0 | 0.8 | GO:0045793 | positive regulation of cell size(GO:0045793) |
0.0 | 0.2 | GO:0098734 | protein depalmitoylation(GO:0002084) negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005) macromolecule depalmitoylation(GO:0098734) |
0.0 | 0.3 | GO:0006020 | inositol metabolic process(GO:0006020) |
0.0 | 0.9 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.0 | 0.0 | GO:0071374 | cellular response to parathyroid hormone stimulus(GO:0071374) |
0.0 | 0.3 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
0.0 | 0.4 | GO:0033262 | regulation of nuclear cell cycle DNA replication(GO:0033262) |
0.0 | 0.5 | GO:0070816 | phosphorylation of RNA polymerase II C-terminal domain(GO:0070816) |
0.0 | 0.3 | GO:1990118 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
0.0 | 0.1 | GO:2000016 | negative regulation of determination of dorsal identity(GO:2000016) |
0.0 | 1.6 | GO:0002181 | cytoplasmic translation(GO:0002181) |
0.0 | 0.4 | GO:1900153 | regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153) |
0.0 | 0.6 | GO:0045948 | positive regulation of translational initiation(GO:0045948) |
0.0 | 0.2 | GO:0018026 | peptidyl-lysine monomethylation(GO:0018026) |
0.0 | 0.1 | GO:0051342 | regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344) |
0.0 | 0.1 | GO:1903527 | positive regulation of membrane tubulation(GO:1903527) |
0.0 | 1.2 | GO:0070206 | protein trimerization(GO:0070206) |
0.0 | 3.0 | GO:0007050 | cell cycle arrest(GO:0007050) |
0.0 | 0.5 | GO:0014829 | vascular smooth muscle contraction(GO:0014829) |
0.0 | 0.5 | GO:0035455 | response to interferon-alpha(GO:0035455) |
0.0 | 0.3 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
0.0 | 0.8 | GO:0097031 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
0.0 | 0.2 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
0.0 | 0.9 | GO:0051591 | response to cAMP(GO:0051591) |
0.0 | 0.2 | GO:0000380 | alternative mRNA splicing, via spliceosome(GO:0000380) |
0.0 | 0.2 | GO:0031119 | tRNA pseudouridine synthesis(GO:0031119) |
0.0 | 2.3 | GO:0043484 | regulation of RNA splicing(GO:0043484) |
0.0 | 0.1 | GO:0009597 | detection of virus(GO:0009597) |
0.0 | 0.8 | GO:0010718 | positive regulation of epithelial to mesenchymal transition(GO:0010718) |
0.0 | 0.6 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
0.0 | 0.5 | GO:0045026 | plasma membrane fusion(GO:0045026) |
0.0 | 0.5 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
0.0 | 0.1 | GO:0015786 | UDP-glucose transport(GO:0015786) |
0.0 | 1.3 | GO:1904893 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
0.0 | 0.6 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
0.0 | 0.1 | GO:0051987 | positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987) |
0.0 | 0.2 | GO:0034453 | microtubule anchoring(GO:0034453) |
0.0 | 0.1 | GO:0099552 | trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553) regulation of intracellular calcium activated chloride channel activity(GO:1902938) |
0.0 | 0.1 | GO:0090267 | positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) |
0.0 | 0.2 | GO:0031274 | positive regulation of pseudopodium assembly(GO:0031274) |
0.0 | 0.1 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
0.0 | 0.8 | GO:0045773 | positive regulation of axon extension(GO:0045773) |
0.0 | 0.2 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
0.0 | 0.0 | GO:0010863 | positive regulation of phospholipase C activity(GO:0010863) |
0.0 | 0.6 | GO:0036075 | endochondral ossification(GO:0001958) replacement ossification(GO:0036075) |
0.0 | 0.3 | GO:0010862 | positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862) |
0.0 | 0.2 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
0.0 | 0.5 | GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I(GO:0002474) |
0.0 | 0.0 | GO:0006083 | acetate metabolic process(GO:0006083) |
0.0 | 0.0 | GO:1900426 | positive regulation of defense response to bacterium(GO:1900426) |
0.0 | 1.4 | GO:0016052 | carbohydrate catabolic process(GO:0016052) |
0.0 | 0.1 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
0.0 | 0.1 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
0.0 | 0.3 | GO:0006376 | mRNA splice site selection(GO:0006376) |
0.0 | 0.2 | GO:0006474 | N-terminal protein amino acid acetylation(GO:0006474) |
0.0 | 0.5 | GO:1900087 | positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) |
0.0 | 0.0 | GO:0003278 | apoptotic process involved in heart morphogenesis(GO:0003278) |
0.0 | 0.9 | GO:0000086 | G2/M transition of mitotic cell cycle(GO:0000086) |
0.0 | 0.1 | GO:0051956 | negative regulation of amino acid transport(GO:0051956) |
0.0 | 0.2 | GO:0034260 | negative regulation of GTPase activity(GO:0034260) |
0.0 | 0.0 | GO:0097029 | mature conventional dendritic cell differentiation(GO:0097029) |
0.0 | 0.4 | GO:0006801 | superoxide metabolic process(GO:0006801) |
0.0 | 1.1 | GO:0010921 | regulation of phosphatase activity(GO:0010921) |
0.0 | 1.4 | GO:0006364 | rRNA processing(GO:0006364) |
0.0 | 0.2 | GO:0032958 | inositol phosphate biosynthetic process(GO:0032958) |
0.0 | 0.3 | GO:0006379 | mRNA cleavage(GO:0006379) |
0.0 | 0.3 | GO:0071425 | hematopoietic stem cell proliferation(GO:0071425) |
0.0 | 0.2 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
0.0 | 0.3 | GO:1904355 | positive regulation of telomere capping(GO:1904355) |
0.0 | 0.9 | GO:0043149 | contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149) |
0.0 | 0.4 | GO:0034605 | cellular response to heat(GO:0034605) |
0.0 | 0.2 | GO:0048266 | behavioral response to pain(GO:0048266) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 2.2 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
0.4 | 4.0 | GO:0000796 | condensin complex(GO:0000796) |
0.4 | 1.4 | GO:0071942 | XPC complex(GO:0071942) |
0.4 | 1.1 | GO:0042720 | mitochondrial inner membrane peptidase complex(GO:0042720) |
0.2 | 2.1 | GO:0005642 | annulate lamellae(GO:0005642) |
0.2 | 1.9 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
0.2 | 0.5 | GO:0097233 | lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233) |
0.2 | 1.7 | GO:0042582 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
0.1 | 2.8 | GO:0031616 | spindle pole centrosome(GO:0031616) |
0.1 | 1.2 | GO:0002177 | manchette(GO:0002177) |
0.1 | 0.4 | GO:0005940 | septin ring(GO:0005940) |
0.1 | 0.6 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
0.1 | 0.6 | GO:1903440 | calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440) |
0.1 | 0.5 | GO:0097447 | dendritic tree(GO:0097447) |
0.1 | 8.5 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
0.1 | 0.3 | GO:0001725 | stress fiber(GO:0001725) actin filament bundle(GO:0032432) actomyosin(GO:0042641) contractile actin filament bundle(GO:0097517) |
0.1 | 2.8 | GO:0000242 | pericentriolar material(GO:0000242) |
0.1 | 1.5 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
0.1 | 1.1 | GO:0044233 | ER-mitochondrion membrane contact site(GO:0044233) |
0.1 | 0.4 | GO:0000243 | commitment complex(GO:0000243) |
0.1 | 0.5 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
0.1 | 0.3 | GO:0055087 | Ski complex(GO:0055087) |
0.1 | 0.3 | GO:0071914 | prominosome(GO:0071914) |
0.1 | 0.9 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
0.1 | 0.4 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
0.1 | 1.1 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
0.1 | 0.4 | GO:1990357 | terminal web(GO:1990357) |
0.1 | 0.8 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) |
0.1 | 2.3 | GO:0071011 | precatalytic spliceosome(GO:0071011) |
0.1 | 0.3 | GO:0030289 | protein phosphatase 4 complex(GO:0030289) |
0.1 | 0.6 | GO:0070765 | gamma-secretase complex(GO:0070765) |
0.1 | 1.5 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
0.1 | 0.9 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
0.1 | 0.9 | GO:0070852 | cell body fiber(GO:0070852) |
0.1 | 0.8 | GO:0042612 | MHC class I protein complex(GO:0042612) |
0.1 | 0.5 | GO:0000439 | core TFIIH complex(GO:0000439) |
0.1 | 0.4 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
0.1 | 1.9 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
0.1 | 1.3 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
0.1 | 0.3 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
0.1 | 0.3 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
0.0 | 0.3 | GO:0042613 | MHC class II protein complex(GO:0042613) |
0.0 | 0.4 | GO:0098533 | ATPase dependent transmembrane transport complex(GO:0098533) |
0.0 | 0.4 | GO:0070652 | HAUS complex(GO:0070652) |
0.0 | 0.5 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
0.0 | 0.7 | GO:0065010 | extracellular membrane-bounded organelle(GO:0065010) |
0.0 | 0.8 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
0.0 | 0.5 | GO:0031209 | SCAR complex(GO:0031209) |
0.0 | 0.4 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
0.0 | 0.4 | GO:0016272 | prefoldin complex(GO:0016272) |
0.0 | 0.6 | GO:0032156 | septin cytoskeleton(GO:0032156) |
0.0 | 0.3 | GO:0045298 | tubulin complex(GO:0045298) |
0.0 | 0.9 | GO:0034451 | centriolar satellite(GO:0034451) |
0.0 | 0.2 | GO:0070876 | SOSS complex(GO:0070876) |
0.0 | 0.3 | GO:0045254 | pyruvate dehydrogenase complex(GO:0045254) |
0.0 | 2.0 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
0.0 | 0.1 | GO:0071006 | U2-type catalytic step 1 spliceosome(GO:0071006) |
0.0 | 1.7 | GO:0015935 | small ribosomal subunit(GO:0015935) |
0.0 | 0.8 | GO:0043218 | compact myelin(GO:0043218) |
0.0 | 0.4 | GO:0044666 | MLL3/4 complex(GO:0044666) |
0.0 | 0.7 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
0.0 | 0.3 | GO:0061574 | ASAP complex(GO:0061574) |
0.0 | 0.8 | GO:0005921 | gap junction(GO:0005921) |
0.0 | 0.2 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
0.0 | 0.7 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
0.0 | 0.5 | GO:0097225 | sperm midpiece(GO:0097225) |
0.0 | 0.9 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
0.0 | 0.2 | GO:0071986 | Ragulator complex(GO:0071986) |
0.0 | 0.4 | GO:0030008 | TRAPP complex(GO:0030008) |
0.0 | 1.0 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
0.0 | 0.8 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
0.0 | 0.4 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
0.0 | 1.2 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
0.0 | 1.1 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
0.0 | 0.4 | GO:1990635 | proximal dendrite(GO:1990635) |
0.0 | 2.1 | GO:0009897 | external side of plasma membrane(GO:0009897) |
0.0 | 5.4 | GO:0030426 | growth cone(GO:0030426) |
0.0 | 1.1 | GO:0045171 | intercellular bridge(GO:0045171) |
0.0 | 0.4 | GO:0031527 | filopodium membrane(GO:0031527) |
0.0 | 0.1 | GO:0031315 | extrinsic component of mitochondrial outer membrane(GO:0031315) |
0.0 | 0.3 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
0.0 | 1.1 | GO:0016328 | lateral plasma membrane(GO:0016328) |
0.0 | 0.1 | GO:0071008 | B cell receptor complex(GO:0019815) U2-type post-mRNA release spliceosomal complex(GO:0071008) |
0.0 | 0.7 | GO:0016529 | sarcoplasmic reticulum(GO:0016529) |
0.0 | 0.1 | GO:0097441 | basilar dendrite(GO:0097441) |
0.0 | 0.5 | GO:0032040 | small-subunit processome(GO:0032040) |
0.0 | 1.0 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
0.0 | 0.5 | GO:0031305 | integral component of mitochondrial inner membrane(GO:0031305) |
0.0 | 0.6 | GO:0042734 | presynaptic membrane(GO:0042734) |
0.0 | 0.5 | GO:0055038 | recycling endosome membrane(GO:0055038) |
0.0 | 0.6 | GO:0031594 | neuromuscular junction(GO:0031594) |
0.0 | 0.3 | GO:0045120 | pronucleus(GO:0045120) |
0.0 | 0.5 | GO:0032590 | dendrite membrane(GO:0032590) |
0.0 | 0.7 | GO:0005844 | polysome(GO:0005844) |
0.0 | 0.1 | GO:0089701 | U2AF(GO:0089701) |
0.0 | 1.8 | GO:0043679 | axon terminus(GO:0043679) |
0.0 | 2.2 | GO:0043209 | myelin sheath(GO:0043209) |
0.0 | 0.2 | GO:0005614 | interstitial matrix(GO:0005614) |
0.0 | 0.1 | GO:1990023 | mitotic spindle midzone(GO:1990023) |
0.0 | 0.2 | GO:0000800 | lateral element(GO:0000800) |
0.0 | 1.5 | GO:0005681 | spliceosomal complex(GO:0005681) |
0.0 | 0.1 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 7.2 | GO:0019992 | diacylglycerol binding(GO:0019992) |
0.5 | 1.4 | GO:0016160 | alpha-amylase activity(GO:0004556) amylase activity(GO:0016160) |
0.4 | 2.2 | GO:0061731 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
0.4 | 2.1 | GO:0042610 | CD8 receptor binding(GO:0042610) |
0.3 | 1.0 | GO:0009881 | photoreceptor activity(GO:0009881) |
0.3 | 1.0 | GO:0008823 | cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851) |
0.3 | 1.9 | GO:1990948 | ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948) |
0.3 | 1.5 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
0.3 | 1.8 | GO:0032795 | heterotrimeric G-protein binding(GO:0032795) |
0.2 | 1.4 | GO:0017040 | ceramidase activity(GO:0017040) |
0.2 | 0.6 | GO:0004993 | G-protein coupled serotonin receptor activity(GO:0004993) |
0.2 | 1.7 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
0.2 | 0.4 | GO:0016725 | oxidoreductase activity, acting on CH or CH2 groups(GO:0016725) |
0.2 | 1.2 | GO:0043426 | MRF binding(GO:0043426) |
0.2 | 1.5 | GO:0035368 | selenocysteine insertion sequence binding(GO:0035368) |
0.2 | 1.9 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
0.2 | 0.6 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
0.2 | 0.7 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
0.2 | 1.5 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
0.2 | 1.1 | GO:0016936 | galactoside binding(GO:0016936) |
0.2 | 0.9 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
0.2 | 1.5 | GO:0030274 | LIM domain binding(GO:0030274) |
0.2 | 1.6 | GO:0031852 | mu-type opioid receptor binding(GO:0031852) |
0.2 | 0.5 | GO:0004828 | serine-tRNA ligase activity(GO:0004828) |
0.1 | 0.6 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
0.1 | 0.6 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
0.1 | 2.2 | GO:0017070 | U6 snRNA binding(GO:0017070) |
0.1 | 1.1 | GO:0015193 | L-proline transmembrane transporter activity(GO:0015193) |
0.1 | 0.7 | GO:0000702 | oxidized base lesion DNA N-glycosylase activity(GO:0000702) |
0.1 | 0.4 | GO:0031798 | type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052) |
0.1 | 0.7 | GO:0031628 | opioid receptor binding(GO:0031628) |
0.1 | 0.5 | GO:0004667 | prostaglandin-D synthase activity(GO:0004667) prostaglandin-E synthase activity(GO:0050220) |
0.1 | 1.3 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
0.1 | 0.5 | GO:0031800 | type 3 metabotropic glutamate receptor binding(GO:0031800) |
0.1 | 1.1 | GO:1990446 | U1 snRNP binding(GO:1990446) |
0.1 | 0.9 | GO:0071558 | histone demethylase activity (H3-K27 specific)(GO:0071558) |
0.1 | 0.6 | GO:0097643 | amylin receptor activity(GO:0097643) |
0.1 | 0.5 | GO:0034481 | chondroitin sulfotransferase activity(GO:0034481) |
0.1 | 1.2 | GO:0050733 | RS domain binding(GO:0050733) |
0.1 | 3.5 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
0.1 | 0.7 | GO:0050694 | galactose 3-O-sulfotransferase activity(GO:0050694) |
0.1 | 0.4 | GO:0004784 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
0.1 | 0.9 | GO:0051022 | Rho GDP-dissociation inhibitor binding(GO:0051022) |
0.1 | 0.5 | GO:0016615 | malate dehydrogenase activity(GO:0016615) |
0.1 | 1.1 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
0.1 | 0.5 | GO:0019770 | IgG receptor activity(GO:0019770) |
0.1 | 0.5 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
0.1 | 0.3 | GO:0035473 | lipase binding(GO:0035473) |
0.1 | 1.8 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
0.1 | 0.5 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
0.1 | 0.9 | GO:0044548 | S100 protein binding(GO:0044548) |
0.1 | 0.4 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
0.1 | 0.5 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) |
0.1 | 0.6 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
0.1 | 0.8 | GO:0048185 | activin binding(GO:0048185) |
0.1 | 0.8 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
0.1 | 0.8 | GO:0030881 | beta-2-microglobulin binding(GO:0030881) |
0.1 | 0.4 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
0.1 | 0.5 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
0.1 | 0.5 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
0.1 | 0.4 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
0.1 | 0.6 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
0.1 | 0.5 | GO:0046790 | virion binding(GO:0046790) |
0.1 | 0.2 | GO:0017153 | sodium:dicarboxylate symporter activity(GO:0017153) |
0.1 | 0.4 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
0.1 | 0.2 | GO:0051765 | inositol tetrakisphosphate kinase activity(GO:0051765) |
0.1 | 0.3 | GO:0004809 | tRNA (guanine-N2-)-methyltransferase activity(GO:0004809) |
0.1 | 0.3 | GO:0034604 | pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604) |
0.1 | 2.5 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
0.1 | 1.3 | GO:0008327 | methyl-CpG binding(GO:0008327) |
0.1 | 8.2 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
0.1 | 0.6 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
0.0 | 0.9 | GO:0001848 | complement binding(GO:0001848) |
0.0 | 0.3 | GO:1990405 | protein antigen binding(GO:1990405) |
0.0 | 0.2 | GO:0010484 | H3 histone acetyltransferase activity(GO:0010484) |
0.0 | 0.2 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
0.0 | 1.2 | GO:0071837 | HMG box domain binding(GO:0071837) |
0.0 | 0.5 | GO:0038191 | neuropilin binding(GO:0038191) |
0.0 | 0.8 | GO:0001968 | fibronectin binding(GO:0001968) |
0.0 | 5.1 | GO:0001158 | enhancer sequence-specific DNA binding(GO:0001158) |
0.0 | 0.2 | GO:1990189 | peptide-serine-N-acetyltransferase activity(GO:1990189) |
0.0 | 0.2 | GO:0070976 | calcium-independent protein kinase C activity(GO:0004699) TIR domain binding(GO:0070976) |
0.0 | 0.6 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
0.0 | 0.3 | GO:0030976 | thiamine pyrophosphate binding(GO:0030976) |
0.0 | 1.1 | GO:0048020 | CCR chemokine receptor binding(GO:0048020) |
0.0 | 0.1 | GO:0050632 | propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121) |
0.0 | 1.7 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
0.0 | 0.6 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
0.0 | 0.3 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) potassium ion antiporter activity(GO:0022821) |
0.0 | 0.5 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.0 | 0.2 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
0.0 | 0.6 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
0.0 | 0.5 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
0.0 | 0.5 | GO:0004659 | prenyltransferase activity(GO:0004659) |
0.0 | 0.2 | GO:0048101 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
0.0 | 0.9 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
0.0 | 0.2 | GO:0019865 | immunoglobulin binding(GO:0019865) |
0.0 | 1.2 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.0 | 0.7 | GO:0097602 | cullin family protein binding(GO:0097602) |
0.0 | 0.1 | GO:0019237 | centromeric DNA binding(GO:0019237) |
0.0 | 0.6 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.0 | 0.9 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
0.0 | 2.0 | GO:0046983 | protein dimerization activity(GO:0046983) |
0.0 | 0.6 | GO:0004385 | guanylate kinase activity(GO:0004385) |
0.0 | 0.3 | GO:0004745 | retinol dehydrogenase activity(GO:0004745) |
0.0 | 0.5 | GO:0051787 | misfolded protein binding(GO:0051787) |
0.0 | 0.5 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
0.0 | 0.5 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
0.0 | 0.3 | GO:0009922 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
0.0 | 0.2 | GO:0051018 | protein kinase A binding(GO:0051018) |
0.0 | 0.2 | GO:0070679 | inositol 1,4,5 trisphosphate binding(GO:0070679) |
0.0 | 1.4 | GO:0051287 | NAD binding(GO:0051287) |
0.0 | 0.2 | GO:0015093 | ferrous iron transmembrane transporter activity(GO:0015093) |
0.0 | 1.5 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.0 | 2.9 | GO:0004721 | phosphoprotein phosphatase activity(GO:0004721) |
0.0 | 0.4 | GO:0008143 | poly(A) binding(GO:0008143) |
0.0 | 0.2 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
0.0 | 2.2 | GO:0030165 | PDZ domain binding(GO:0030165) |
0.0 | 0.3 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
0.0 | 1.3 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
0.0 | 0.2 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
0.0 | 0.8 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
0.0 | 0.1 | GO:0036004 | GAF domain binding(GO:0036004) |
0.0 | 0.3 | GO:0000983 | transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983) |
0.0 | 0.2 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
0.0 | 0.1 | GO:0031683 | G-protein beta/gamma-subunit complex binding(GO:0031683) |
0.0 | 0.0 | GO:0003987 | acetate-CoA ligase activity(GO:0003987) |
0.0 | 0.6 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
0.0 | 0.0 | GO:0034189 | very-low-density lipoprotein particle binding(GO:0034189) |
0.0 | 0.1 | GO:0003854 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) |
0.0 | 0.3 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.0 | 0.1 | GO:0001639 | PLC activating G-protein coupled glutamate receptor activity(GO:0001639) A2A adenosine receptor binding(GO:0031687) G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530) |
0.0 | 0.7 | GO:0016836 | hydro-lyase activity(GO:0016836) |
0.0 | 0.5 | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) |
0.0 | 0.1 | GO:0015187 | glycine transmembrane transporter activity(GO:0015187) |
0.0 | 0.0 | GO:0033691 | sialic acid binding(GO:0033691) |
0.0 | 1.0 | GO:0005178 | integrin binding(GO:0005178) |
0.0 | 0.3 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
0.0 | 1.3 | GO:0016810 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810) |
0.0 | 0.4 | GO:0005179 | hormone activity(GO:0005179) |
0.0 | 0.4 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
0.0 | 0.2 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 0.9 | PID_AMB2_NEUTROPHILS_PATHWAY | amb2 Integrin signaling |
0.2 | 7.5 | PID_RAS_PATHWAY | Regulation of Ras family activation |
0.1 | 1.8 | PID_INTEGRIN2_PATHWAY | Beta2 integrin cell surface interactions |
0.1 | 1.6 | PID_EPHA2_FWD_PATHWAY | EPHA2 forward signaling |
0.1 | 3.9 | PID_AURORA_B_PATHWAY | Aurora B signaling |
0.1 | 2.1 | PID_NFKAPPAB_ATYPICAL_PATHWAY | Atypical NF-kappaB pathway |
0.1 | 0.8 | PID_ALK2_PATHWAY | ALK2 signaling events |
0.0 | 0.5 | PID_CONE_PATHWAY | Visual signal transduction: Cones |
0.0 | 0.4 | PID_AVB3_OPN_PATHWAY | Osteopontin-mediated events |
0.0 | 1.4 | PID_AURORA_A_PATHWAY | Aurora A signaling |
0.0 | 0.5 | PID_RAC1_PATHWAY | RAC1 signaling pathway |
0.0 | 0.6 | PID_SYNDECAN_3_PATHWAY | Syndecan-3-mediated signaling events |
0.0 | 3.9 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.0 | 1.6 | PID_FANCONI_PATHWAY | Fanconi anemia pathway |
0.0 | 0.9 | PID_ER_NONGENOMIC_PATHWAY | Plasma membrane estrogen receptor signaling |
0.0 | 1.1 | PID_BETA_CATENIN_NUC_PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
0.0 | 0.8 | PID_TCR_CALCIUM_PATHWAY | Calcium signaling in the CD4+ TCR pathway |
0.0 | 0.8 | PID_ECADHERIN_NASCENT_AJ_PATHWAY | E-cadherin signaling in the nascent adherens junction |
0.0 | 0.4 | PID_CIRCADIAN_PATHWAY | Circadian rhythm pathway |
0.0 | 1.8 | PID_P53_REGULATION_PATHWAY | p53 pathway |
0.0 | 0.3 | PID_HES_HEY_PATHWAY | Notch-mediated HES/HEY network |
0.0 | 0.5 | PID_ECADHERIN_KERATINOCYTE_PATHWAY | E-cadherin signaling in keratinocytes |
0.0 | 0.6 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
0.0 | 0.8 | PID_A6B1_A6B4_INTEGRIN_PATHWAY | a6b1 and a6b4 Integrin signaling |
0.0 | 2.8 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
0.0 | 1.3 | PID_CDC42_PATHWAY | CDC42 signaling events |
0.0 | 0.6 | ST_P38_MAPK_PATHWAY | p38 MAPK Pathway |
0.0 | 1.5 | WNT_SIGNALING | Genes related to Wnt-mediated signal transduction |
0.0 | 1.4 | PID_HDAC_CLASSI_PATHWAY | Signaling events mediated by HDAC Class I |
0.0 | 0.5 | PID_IL6_7_PATHWAY | IL6-mediated signaling events |
0.0 | 1.7 | PID_P53_DOWNSTREAM_PATHWAY | Direct p53 effectors |
0.0 | 0.4 | PID_ILK_PATHWAY | Integrin-linked kinase signaling |
0.0 | 0.5 | PID_TRKR_PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 2.1 | REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |
0.2 | 1.9 | REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
0.2 | 7.8 | REACTOME_RAP1_SIGNALLING | Genes involved in Rap1 signalling |
0.2 | 0.6 | REACTOME_SEROTONIN_RECEPTORS | Genes involved in Serotonin receptors |
0.1 | 3.2 | REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
0.1 | 1.1 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
0.1 | 9.8 | REACTOME_PEPTIDE_CHAIN_ELONGATION | Genes involved in Peptide chain elongation |
0.1 | 0.3 | REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS | Genes involved in Eicosanoid ligand-binding receptors |
0.1 | 2.1 | REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
0.1 | 1.6 | REACTOME_FANCONI_ANEMIA_PATHWAY | Genes involved in Fanconi Anemia pathway |
0.1 | 1.3 | REACTOME_CRMPS_IN_SEMA3A_SIGNALING | Genes involved in CRMPs in Sema3A signaling |
0.1 | 1.1 | REACTOME_METABOLISM_OF_POLYAMINES | Genes involved in Metabolism of polyamines |
0.1 | 0.5 | REACTOME_ENDOGENOUS_STEROLS | Genes involved in Endogenous sterols |
0.1 | 1.1 | REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |
0.1 | 0.8 | REACTOME_CD28_DEPENDENT_VAV1_PATHWAY | Genes involved in CD28 dependent Vav1 pathway |
0.1 | 1.4 | REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
0.1 | 0.8 | REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
0.1 | 0.7 | REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
0.1 | 0.7 | REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
0.1 | 0.7 | REACTOME_PURINE_CATABOLISM | Genes involved in Purine catabolism |
0.1 | 0.5 | REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN | Genes involved in Signalling to p38 via RIT and RIN |
0.1 | 1.4 | REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
0.1 | 2.0 | REACTOME_GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
0.1 | 0.9 | REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
0.0 | 0.8 | REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
0.0 | 0.5 | REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX | Genes involved in Degradation of the extracellular matrix |
0.0 | 1.7 | REACTOME_LYSOSOME_VESICLE_BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
0.0 | 1.2 | REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
0.0 | 0.6 | REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR | Genes involved in Regulated proteolysis of p75NTR |
0.0 | 0.9 | REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI | Genes involved in RIP-mediated NFkB activation via DAI |
0.0 | 1.1 | REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA | Genes involved in G beta:gamma signalling through PLC beta |
0.0 | 0.4 | REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
0.0 | 0.5 | REACTOME_MTORC1_MEDIATED_SIGNALLING | Genes involved in mTORC1-mediated signalling |
0.0 | 0.6 | REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
0.0 | 0.5 | REACTOME_ACTIVATION_OF_KAINATE_RECEPTORS_UPON_GLUTAMATE_BINDING | Genes involved in Activation of Kainate Receptors upon glutamate binding |
0.0 | 1.1 | REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
0.0 | 0.3 | REACTOME_AMINE_DERIVED_HORMONES | Genes involved in Amine-derived hormones |
0.0 | 0.5 | REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
0.0 | 0.9 | REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE | Genes involved in GPVI-mediated activation cascade |
0.0 | 0.9 | REACTOME_MRNA_3_END_PROCESSING | Genes involved in mRNA 3'-end processing |
0.0 | 1.6 | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT | Genes involved in Respiratory electron transport |
0.0 | 0.2 | REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
0.0 | 0.5 | REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER | Genes involved in Formation of incision complex in GG-NER |
0.0 | 0.9 | REACTOME_MRNA_SPLICING_MINOR_PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
0.0 | 0.5 | REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
0.0 | 1.5 | REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
0.0 | 0.4 | REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 | Genes involved in Nuclear signaling by ERBB4 |
0.0 | 0.9 | REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT | Genes involved in Mitochondrial Protein Import |
0.0 | 1.4 | REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
0.0 | 0.2 | REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING | Genes involved in Role of second messengers in netrin-1 signaling |
0.0 | 2.2 | REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS | Genes involved in Class A/1 (Rhodopsin-like receptors) |
0.0 | 0.2 | REACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE | Genes involved in Formation of Fibrin Clot (Clotting Cascade) |
0.0 | 0.9 | REACTOME_MRNA_SPLICING | Genes involved in mRNA Splicing |
0.0 | 0.5 | REACTOME_SMOOTH_MUSCLE_CONTRACTION | Genes involved in Smooth Muscle Contraction |
0.0 | 0.2 | REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
0.0 | 0.5 | REACTOME_PACKAGING_OF_TELOMERE_ENDS | Genes involved in Packaging Of Telomere Ends |
0.0 | 0.4 | REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM | Genes involved in Transport of Mature Transcript to Cytoplasm |
0.0 | 0.4 | REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |
0.0 | 0.3 | REACTOME_SIGNALING_BY_PDGF | Genes involved in Signaling by PDGF |
0.0 | 0.1 | REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
0.0 | 0.1 | REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
0.0 | 0.5 | REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS | Genes involved in G alpha (z) signalling events |
0.0 | 0.2 | REACTOME_ENOS_ACTIVATION_AND_REGULATION | Genes involved in eNOS activation and regulation |
0.0 | 0.2 | REACTOME_OTHER_SEMAPHORIN_INTERACTIONS | Genes involved in Other semaphorin interactions |
0.0 | 0.2 | REACTOME_IL_RECEPTOR_SHC_SIGNALING | Genes involved in Interleukin receptor SHC signaling |
0.0 | 0.4 | REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |