Motif ID: Stat1

Z-value: 0.785


Transcription factors associated with Stat1:

Gene SymbolEntrez IDGene Name
Stat1 ENSMUSG00000026104.8 Stat1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Stat1mm10_v2_chr1_+_52119438_521194990.296.7e-02Click!


Activity profile for motif Stat1.

activity profile for motif Stat1


Sorted Z-values histogram for motif Stat1

Sorted Z-values for motif Stat1



Network of associatons between targets according to the STRING database.



First level regulatory network of Stat1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_80802789 5.981 ENSMUST00000107745.1
ENSMUST00000075316.4
Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr11_+_78499087 3.970 ENSMUST00000017488.4
Vtn
vitronectin
chrX_-_61185558 3.440 ENSMUST00000166381.1
Cdr1
cerebellar degeneration related antigen 1
chr9_-_96719404 3.430 ENSMUST00000140121.1
Zbtb38
zinc finger and BTB domain containing 38
chr6_+_115134899 3.301 ENSMUST00000009538.5
ENSMUST00000169345.1
Syn2

synapsin II

chr1_-_155417394 3.201 ENSMUST00000111775.1
ENSMUST00000111774.1
Xpr1

xenotropic and polytropic retrovirus receptor 1

chr10_+_69925766 2.844 ENSMUST00000182269.1
ENSMUST00000183261.1
ENSMUST00000183074.1
Ank3


ankyrin 3, epithelial


chr4_-_108031938 2.740 ENSMUST00000106708.1
Podn
podocan
chr10_+_69925954 2.692 ENSMUST00000181974.1
ENSMUST00000182795.1
ENSMUST00000182437.1
Ank3


ankyrin 3, epithelial


chr10_+_69925800 2.623 ENSMUST00000182029.1
Ank3
ankyrin 3, epithelial
chr9_-_96719549 2.580 ENSMUST00000128269.1
Zbtb38
zinc finger and BTB domain containing 38
chr4_-_108032069 2.544 ENSMUST00000106709.2
Podn
podocan
chr1_-_155417283 2.462 ENSMUST00000027741.5
Xpr1
xenotropic and polytropic retrovirus receptor 1
chr11_+_101245996 2.298 ENSMUST00000129680.1
Ramp2
receptor (calcitonin) activity modifying protein 2
chr16_-_74411776 2.084 ENSMUST00000116586.2
Robo2
roundabout homolog 2 (Drosophila)
chr7_+_24134148 2.000 ENSMUST00000056549.7
Zfp235
zinc finger protein 235
chr13_+_109903089 1.858 ENSMUST00000120664.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr7_+_82335732 1.855 ENSMUST00000173287.1
Adamtsl3
ADAMTS-like 3
chr7_+_45783686 1.702 ENSMUST00000118564.1
ENSMUST00000133428.1
Lmtk3

lemur tyrosine kinase 3

chr7_+_24112314 1.694 ENSMUST00000120006.1
ENSMUST00000005413.3
Zfp112

zinc finger protein 112

chr1_-_64121389 1.621 ENSMUST00000055001.3
Klf7
Kruppel-like factor 7 (ubiquitous)
chr10_+_40349265 1.619 ENSMUST00000044672.4
ENSMUST00000095743.2
Cdk19

cyclin-dependent kinase 19

chr5_-_123140135 1.594 ENSMUST00000160099.1
AI480526
expressed sequence AI480526
chr4_+_43401232 1.570 ENSMUST00000125399.1
Rusc2
RUN and SH3 domain containing 2
chr1_+_34005872 1.539 ENSMUST00000182296.1
Dst
dystonin
chr13_-_67755132 1.534 ENSMUST00000091520.6
Zfp85-rs1
zinc finger protein 85, related sequence 1
chr18_+_37320374 1.516 ENSMUST00000078271.2
Pcdhb5
protocadherin beta 5
chr7_+_45783883 1.506 ENSMUST00000072580.5
Lmtk3
lemur tyrosine kinase 3
chr9_+_32224457 1.469 ENSMUST00000183121.1
Arhgap32
Rho GTPase activating protein 32
chr2_+_178193075 1.461 ENSMUST00000103065.1
Phactr3
phosphatase and actin regulator 3
chr2_+_3424123 1.457 ENSMUST00000061852.5
ENSMUST00000100463.3
ENSMUST00000102988.3
ENSMUST00000115066.1
Dclre1c



DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae)



chr7_+_29768552 1.456 ENSMUST00000032802.4
Zfp84
zinc finger protein 84
chr2_-_168712853 1.445 ENSMUST00000123156.1
ENSMUST00000156555.1
Atp9a

ATPase, class II, type 9A

chr9_+_20868628 1.445 ENSMUST00000043911.7
A230050P20Rik
RIKEN cDNA A230050P20 gene
chr15_-_54919961 1.433 ENSMUST00000167541.2
ENSMUST00000041591.9
ENSMUST00000173516.1
Enpp2


ectonucleotide pyrophosphatase/phosphodiesterase 2


chr9_+_107296843 1.412 ENSMUST00000167072.1
Cish
cytokine inducible SH2-containing protein
chr7_-_105399991 1.395 ENSMUST00000118726.1
ENSMUST00000074686.7
ENSMUST00000122327.1
ENSMUST00000179474.1
ENSMUST00000048079.6
Fam160a2




family with sequence similarity 160, member A2




chr13_-_67755192 1.393 ENSMUST00000144183.1
Zfp85-rs1
zinc finger protein 85, related sequence 1
chr8_-_67910911 1.386 ENSMUST00000093468.5
Psd3
pleckstrin and Sec7 domain containing 3
chr14_+_84443553 1.384 ENSMUST00000071370.5
Pcdh17
protocadherin 17
chr11_-_98729374 1.378 ENSMUST00000126565.1
ENSMUST00000100500.2
ENSMUST00000017354.6
Med24


mediator complex subunit 24


chr2_-_127584668 1.350 ENSMUST00000110368.2
ENSMUST00000077422.5
Zfp661

zinc finger protein 661

chr8_-_105326252 1.333 ENSMUST00000070508.7
Lrrc29
leucine rich repeat containing 29
chr16_-_20426322 1.330 ENSMUST00000115547.2
ENSMUST00000096199.4
Abcc5

ATP-binding cassette, sub-family C (CFTR/MRP), member 5

chr7_-_78577771 1.294 ENSMUST00000039438.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr10_-_95417099 1.285 ENSMUST00000135822.1
Socs2
suppressor of cytokine signaling 2
chr3_+_96576984 1.284 ENSMUST00000148290.1
Gm16253
predicted gene 16253
chr9_+_45117813 1.249 ENSMUST00000170998.1
ENSMUST00000093855.3
Scn2b

sodium channel, voltage-gated, type II, beta

chr3_-_10440054 1.218 ENSMUST00000099223.4
ENSMUST00000029047.6
Snx16

sorting nexin 16

chrX_-_47892396 1.209 ENSMUST00000153548.2
Smarca1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr10_-_95416850 1.196 ENSMUST00000020215.9
Socs2
suppressor of cytokine signaling 2
chr19_-_46327121 1.182 ENSMUST00000041391.4
ENSMUST00000096029.5
Psd

pleckstrin and Sec7 domain containing

chr16_-_20425881 1.076 ENSMUST00000077867.3
Abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr9_+_107296682 1.074 ENSMUST00000168260.1
Cish
cytokine inducible SH2-containing protein
chr2_-_120970706 1.073 ENSMUST00000028728.5
Ubr1
ubiquitin protein ligase E3 component n-recognin 1
chr7_-_24316590 1.054 ENSMUST00000108436.1
ENSMUST00000032673.8
Zfp94

zinc finger protein 94

chr18_-_33464007 1.048 ENSMUST00000168890.1
Nrep
neuronal regeneration related protein
chr18_-_33463615 1.040 ENSMUST00000051087.8
Nrep
neuronal regeneration related protein
chr4_-_136886187 1.026 ENSMUST00000046384.8
C1qb
complement component 1, q subcomponent, beta polypeptide
chr18_-_33463747 1.026 ENSMUST00000171533.1
Nrep
neuronal regeneration related protein
chr1_-_64121456 1.001 ENSMUST00000142009.1
ENSMUST00000114086.1
Klf7

Kruppel-like factor 7 (ubiquitous)

chr16_-_42340595 0.979 ENSMUST00000102817.4
Gap43
growth associated protein 43
chr15_-_93519499 0.977 ENSMUST00000109255.2
Prickle1
prickle homolog 1 (Drosophila)
chr19_-_37207293 0.960 ENSMUST00000132580.1
ENSMUST00000079754.4
ENSMUST00000136286.1
ENSMUST00000126188.1
ENSMUST00000126781.1
Cpeb3




cytoplasmic polyadenylation element binding protein 3




chr4_-_140617062 0.957 ENSMUST00000154979.1
Arhgef10l
Rho guanine nucleotide exchange factor (GEF) 10-like
chr4_+_148140699 0.954 ENSMUST00000140049.1
ENSMUST00000105707.1
Mad2l2

MAD2 mitotic arrest deficient-like 2

chr8_+_11728105 0.942 ENSMUST00000110909.2
ENSMUST00000033908.6
Arhgef7

Rho guanine nucleotide exchange factor (GEF7)

chr7_+_29816061 0.941 ENSMUST00000032796.6
ENSMUST00000178162.1
Zfp790

zinc finger protein 790

chr11_-_106579111 0.925 ENSMUST00000103070.2
Tex2
testis expressed gene 2
chr7_-_100856289 0.887 ENSMUST00000139604.1
Relt
RELT tumor necrosis factor receptor
chr16_-_20426375 0.886 ENSMUST00000079158.6
Abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr10_-_18234930 0.883 ENSMUST00000052648.8
ENSMUST00000080860.6
ENSMUST00000173243.1
Ccdc28a


coiled-coil domain containing 28A


chr8_-_70776650 0.809 ENSMUST00000034296.8
Pik3r2
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta)
chr17_+_34187545 0.805 ENSMUST00000170086.1
Tap1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr17_-_68004075 0.801 ENSMUST00000024840.5
Arhgap28
Rho GTPase activating protein 28
chr3_-_108210438 0.800 ENSMUST00000117784.1
ENSMUST00000119650.1
ENSMUST00000117409.1
Atxn7l2


ataxin 7-like 2


chr11_+_101425068 0.761 ENSMUST00000040561.5
Rundc1
RUN domain containing 1
chr7_+_30095150 0.760 ENSMUST00000130526.1
ENSMUST00000108200.1
Zfp260

zinc finger protein 260

chr6_+_127446819 0.759 ENSMUST00000112191.1
Parp11
poly (ADP-ribose) polymerase family, member 11
chrX_+_48623737 0.742 ENSMUST00000114936.1
Slc25a14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr4_-_11965699 0.713 ENSMUST00000108301.1
ENSMUST00000095144.3
ENSMUST00000108302.1
Pdp1


pyruvate dehyrogenase phosphatase catalytic subunit 1


chr12_+_11265867 0.711 ENSMUST00000020931.5
Smc6
structural maintenance of chromosomes 6
chr9_+_54538984 0.710 ENSMUST00000060242.5
ENSMUST00000118413.1
Sh2d7

SH2 domain containing 7

chr4_+_148602527 0.710 ENSMUST00000105701.2
ENSMUST00000052060.6
Masp2

mannan-binding lectin serine peptidase 2

chr2_-_84775388 0.696 ENSMUST00000023994.3
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr15_-_54920115 0.695 ENSMUST00000171545.1
Enpp2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr7_+_27591705 0.689 ENSMUST00000167435.1
Akt2
thymoma viral proto-oncogene 2
chr5_-_34513892 0.686 ENSMUST00000114359.1
ENSMUST00000030991.7
ENSMUST00000087737.3
Tnip2


TNFAIP3 interacting protein 2


chr17_+_34187789 0.669 ENSMUST00000041633.8
Tap1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr17_-_45592569 0.665 ENSMUST00000163492.1
Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr16_+_17508947 0.662 ENSMUST00000023444.3
Lztr1
leucine-zipper-like transcriptional regulator, 1
chrX_-_101419788 0.657 ENSMUST00000117901.1
ENSMUST00000120201.1
ENSMUST00000117637.1
ENSMUST00000134005.1
ENSMUST00000121520.1
Zmym3




zinc finger, MYM-type 3




chr9_+_86571965 0.641 ENSMUST00000034988.3
ENSMUST00000179212.1
Rwdd2a

RWD domain containing 2A

chr17_+_34145231 0.638 ENSMUST00000171231.1
H2-DMb2
histocompatibility 2, class II, locus Mb2
chr16_+_91372783 0.633 ENSMUST00000023693.7
ENSMUST00000134491.2
ENSMUST00000117836.1
Ifnar2


interferon (alpha and beta) receptor 2


chr2_-_84775420 0.624 ENSMUST00000111641.1
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr5_+_14025305 0.619 ENSMUST00000073957.6
Sema3e
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr13_-_34002740 0.619 ENSMUST00000167237.1
ENSMUST00000168400.1
Serpinb6a

serine (or cysteine) peptidase inhibitor, clade B, member 6a

chr7_-_126625676 0.615 ENSMUST00000032961.3
Nupr1
nuclear protein transcription regulator 1
chr4_+_49521176 0.606 ENSMUST00000042964.6
ENSMUST00000107696.1
Zfp189

zinc finger protein 189

chr11_+_82101836 0.602 ENSMUST00000000194.3
Ccl12
chemokine (C-C motif) ligand 12
chr13_-_85288999 0.563 ENSMUST00000109552.2
Rasa1
RAS p21 protein activator 1
chr8_+_105326354 0.553 ENSMUST00000015000.5
ENSMUST00000098453.2
Tmem208

transmembrane protein 208

chr2_+_150749036 0.542 ENSMUST00000094467.5
Entpd6
ectonucleoside triphosphate diphosphohydrolase 6
chr16_+_91372865 0.514 ENSMUST00000089042.6
Ifnar2
interferon (alpha and beta) receptor 2
chr17_-_45592485 0.508 ENSMUST00000166119.1
Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr7_-_13053684 0.483 ENSMUST00000182490.1
Mzf1
myeloid zinc finger 1
chr10_+_128303322 0.462 ENSMUST00000005825.6
Pan2
PAN2 polyA specific ribonuclease subunit homolog (S. cerevisiae)
chr9_+_86743616 0.414 ENSMUST00000036426.6
Prss35
protease, serine, 35
chr16_+_21794384 0.403 ENSMUST00000180830.1
1300002E11Rik
RIKEN cDNA 1300002E11 gene
chr17_-_24527925 0.392 ENSMUST00000176652.1
Traf7
TNF receptor-associated factor 7
chr11_-_45955183 0.385 ENSMUST00000109254.1
Thg1l
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr10_-_127041513 0.379 ENSMUST00000116231.2
Mettl21b
methyltransferase like 21B
chrX_+_7728439 0.379 ENSMUST00000033489.7
Praf2
PRA1 domain family 2
chr8_-_124569696 0.371 ENSMUST00000063278.6
Agt
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr13_-_34002784 0.368 ENSMUST00000166354.1
ENSMUST00000076532.7
ENSMUST00000171034.1
Serpinb6a


serine (or cysteine) peptidase inhibitor, clade B, member 6a


chr17_-_24527830 0.364 ENSMUST00000176353.1
ENSMUST00000176237.1
Traf7

TNF receptor-associated factor 7

chr16_-_35871544 0.359 ENSMUST00000042665.8
Parp14
poly (ADP-ribose) polymerase family, member 14
chr3_-_51560816 0.351 ENSMUST00000037141.7
Setd7
SET domain containing (lysine methyltransferase) 7
chr4_+_83417715 0.344 ENSMUST00000030206.3
ENSMUST00000071544.4
Snapc3

small nuclear RNA activating complex, polypeptide 3

chr17_-_27728889 0.336 ENSMUST00000167489.1
ENSMUST00000138970.1
ENSMUST00000114870.1
ENSMUST00000025054.2
Spdef



SAM pointed domain containing ets transcription factor



chr7_+_24270420 0.324 ENSMUST00000108438.3
Zfp93
zinc finger protein 93
chr8_+_86745679 0.323 ENSMUST00000098532.2
Gm10638
predicted gene 10638
chr2_+_164403194 0.293 ENSMUST00000017151.1
Rbpjl
recombination signal binding protein for immunoglobulin kappa J region-like
chr14_+_55604550 0.292 ENSMUST00000138037.1
Irf9
interferon regulatory factor 9
chr12_-_100520778 0.277 ENSMUST00000062957.6
Ttc7b
tetratricopeptide repeat domain 7B
chr2_-_66634952 0.263 ENSMUST00000100064.2
ENSMUST00000100063.2
Scn9a

sodium channel, voltage-gated, type IX, alpha

chr18_-_3281036 0.261 ENSMUST00000049942.6
ENSMUST00000139537.1
ENSMUST00000124747.1
Crem


cAMP responsive element modulator


chr1_+_136624901 0.260 ENSMUST00000047734.8
ENSMUST00000112046.1
Zfp281

zinc finger protein 281

chr2_-_37422869 0.258 ENSMUST00000112936.1
ENSMUST00000112934.1
Rc3h2

ring finger and CCCH-type zinc finger domains 2

chr17_+_35470083 0.253 ENSMUST00000174525.1
ENSMUST00000068291.6
H2-Q10

histocompatibility 2, Q region locus 10

chr18_-_52529847 0.251 ENSMUST00000171470.1
Lox
lysyl oxidase
chr13_-_41847482 0.250 ENSMUST00000072012.3
Adtrp
androgen dependent TFPI regulating protein
chr10_-_128409632 0.247 ENSMUST00000172348.1
ENSMUST00000166608.1
ENSMUST00000164199.1
ENSMUST00000171370.1
ENSMUST00000026439.7
Nabp2




nucleic acid binding protein 2




chr18_+_42511496 0.232 ENSMUST00000025375.7
Tcerg1
transcription elongation regulator 1 (CA150)
chr11_-_101425330 0.229 ENSMUST00000103102.3
Ptges3l
prostaglandin E synthase 3 (cytosolic)-like
chr11_-_72215592 0.226 ENSMUST00000021157.8
Med31
mediator of RNA polymerase II transcription, subunit 31 homolog (yeast)
chr5_-_140702241 0.223 ENSMUST00000077890.5
ENSMUST00000041783.7
ENSMUST00000142081.1
Iqce


IQ motif containing E


chr10_-_18023229 0.214 ENSMUST00000020002.7
Abracl
ABRA C-terminal like
chr15_-_53346118 0.211 ENSMUST00000077273.2
Ext1
exostoses (multiple) 1
chr8_+_25601591 0.189 ENSMUST00000155861.1
Whsc1l1
Wolf-Hirschhorn syndrome candidate 1-like 1 (human)
chr5_+_67260565 0.187 ENSMUST00000037918.5
ENSMUST00000162543.1
Tmem33

transmembrane protein 33

chr15_-_78305603 0.186 ENSMUST00000096356.3
Csf2rb2
colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)
chr11_-_77787747 0.182 ENSMUST00000092883.2
Gm10277
predicted gene 10277
chr9_+_44981779 0.173 ENSMUST00000034602.7
Cd3d
CD3 antigen, delta polypeptide
chr3_-_90490975 0.157 ENSMUST00000149884.1
Snapin
SNAP-associated protein
chr9_+_86743641 0.156 ENSMUST00000179574.1
Prss35
protease, serine, 35
chr6_+_29468068 0.154 ENSMUST00000143101.1
Atp6v1f
ATPase, H+ transporting, lysosomal V1 subunit F
chr11_+_77765588 0.145 ENSMUST00000164315.1
Myo18a
myosin XVIIIA
chr11_+_78536393 0.135 ENSMUST00000050366.8
ENSMUST00000108275.1
Ift20

intraflagellar transport 20

chr11_+_78536355 0.132 ENSMUST00000128788.1
Ift20
intraflagellar transport 20
chr16_+_21794320 0.130 ENSMUST00000181780.1
ENSMUST00000181960.1
1300002E11Rik

RIKEN cDNA 1300002E11 gene

chr4_+_128759258 0.121 ENSMUST00000030585.7
A3galt2
alpha 1,3-galactosyltransferase 2 (isoglobotriaosylceramide synthase)
chr9_-_59486610 0.117 ENSMUST00000171975.1
Arih1
ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila)
chr1_+_37890477 0.109 ENSMUST00000027256.5
Mrpl30
mitochondrial ribosomal protein L30
chr18_-_52529692 0.090 ENSMUST00000025409.7
Lox
lysyl oxidase
chr2_-_155729359 0.078 ENSMUST00000040833.4
Edem2
ER degradation enhancer, mannosidase alpha-like 2
chr13_-_41847626 0.071 ENSMUST00000121404.1
Adtrp
androgen dependent TFPI regulating protein
chr2_+_101886249 0.070 ENSMUST00000028584.7
Commd9
COMM domain containing 9
chr3_-_57294880 0.059 ENSMUST00000171384.1
Tm4sf1
transmembrane 4 superfamily member 1
chr3_+_89418443 0.055 ENSMUST00000039110.5
ENSMUST00000125036.1
ENSMUST00000154791.1
ENSMUST00000128238.1
ENSMUST00000107417.2
Shc1




src homology 2 domain-containing transforming protein C1




chr1_+_171213969 0.052 ENSMUST00000005820.4
ENSMUST00000075469.5
ENSMUST00000155126.1
Nr1i3


nuclear receptor subfamily 1, group I, member 3


chr10_-_127070254 0.041 ENSMUST00000060991.4
Tspan31
tetraspanin 31
chr11_-_46312220 0.039 ENSMUST00000129474.1
ENSMUST00000093166.4
ENSMUST00000165599.2
Cyfip2


cytoplasmic FMR1 interacting protein 2


chr17_-_34187219 0.037 ENSMUST00000173831.1
Psmb9
proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)
chr13_-_46727932 0.029 ENSMUST00000021803.9
Nup153
nucleoporin 153
chr11_-_60046477 0.026 ENSMUST00000000310.7
ENSMUST00000102693.2
ENSMUST00000148512.1
Pemt


phosphatidylethanolamine N-methyltransferase


chr1_-_172027251 0.016 ENSMUST00000138714.1
Vangl2
vang-like 2 (van gogh, Drosophila)
chr4_+_11704439 0.004 ENSMUST00000108304.2
Gem
GTP binding protein (gene overexpressed in skeletal muscle)
chr14_-_70627008 0.003 ENSMUST00000110984.2
Dmtn
dematin actin binding protein

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 5.7 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) phosphate ion transmembrane transport(GO:0035435) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.7 8.2 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.7 2.1 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.4 1.3 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.4 1.3 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.4 2.3 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.4 0.4 GO:1903598 positive regulation of gap junction assembly(GO:1903598)
0.4 1.5 GO:0046967 cytosol to ER transport(GO:0046967)
0.4 4.0 GO:0097421 liver regeneration(GO:0097421)
0.3 3.1 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.3 1.0 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.3 1.0 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.3 1.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.2 1.2 GO:0046684 response to pyrethroid(GO:0046684)
0.2 1.0 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.2 0.6 GO:2000501 natural killer cell chemotaxis(GO:0035747) negative regulation of lymphocyte migration(GO:2000402) regulation of natural killer cell chemotaxis(GO:2000501)
0.2 0.8 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.2 1.0 GO:0016198 axon choice point recognition(GO:0016198)
0.2 6.0 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.2 1.5 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.2 0.7 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 1.2 GO:0015862 uridine transport(GO:0015862)
0.1 1.9 GO:1901898 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.6 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 0.7 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.1 9.2 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 0.7 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.1 1.4 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.1 2.6 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.4 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 0.2 GO:0070200 establishment of protein localization to telomere(GO:0070200)
0.1 0.2 GO:0072553 terminal button organization(GO:0072553)
0.1 2.6 GO:0034340 response to type I interferon(GO:0034340)
0.1 0.7 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.1 1.5 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 0.6 GO:2000194 regulation of female gonad development(GO:2000194)
0.1 1.2 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 0.8 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.6 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.1 1.0 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.5 GO:0032026 response to magnesium ion(GO:0032026)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.7 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.4 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.3 GO:0009301 snRNA transcription(GO:0009301)
0.0 0.3 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 0.3 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.0 3.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.6 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0 1.0 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.1 GO:1903028 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 1.4 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 0.5 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.0 1.4 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 1.0 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.0 0.3 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.2 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.1 GO:1904154 trimming of terminal mannose on B branch(GO:0036509) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0 0.3 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.8 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 1.2 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 2.7 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015)
0.0 1.4 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 4.5 GO:0006275 regulation of DNA replication(GO:0006275)
0.0 1.2 GO:0050729 positive regulation of inflammatory response(GO:0050729)
0.0 0.6 GO:0001953 negative regulation of cell-matrix adhesion(GO:0001953)
0.0 0.3 GO:0048266 behavioral response to pain(GO:0048266)
0.0 1.5 GO:0007416 synapse assembly(GO:0007416)
0.0 0.1 GO:0030259 lipid glycosylation(GO:0030259)
0.0 2.6 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.8 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.3 GO:0010172 embryonic body morphogenesis(GO:0010172)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.0 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.5 2.3 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.4 8.2 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.4 1.5 GO:0031673 H zone(GO:0031673)
0.3 1.2 GO:0090537 CERF complex(GO:0090537)
0.3 6.0 GO:0032279 asymmetric synapse(GO:0032279)
0.2 0.7 GO:0035061 interchromatin granule(GO:0035061)
0.2 1.5 GO:0042825 TAP complex(GO:0042825)
0.2 1.4 GO:0070695 FHF complex(GO:0070695)
0.2 1.0 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.2 0.5 GO:0031251 PAN complex(GO:0031251)
0.2 1.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.9 GO:0000322 storage vacuole(GO:0000322)
0.1 1.5 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.1 1.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.6 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 6.9 GO:0072562 blood microparticle(GO:0072562)
0.1 2.1 GO:0030673 axolemma(GO:0030673)
0.1 0.3 GO:1902636 kinociliary basal body(GO:1902636)
0.1 3.3 GO:0031201 SNARE complex(GO:0031201)
0.1 1.0 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 1.0 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 1.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 2.3 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.7 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 0.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.0 GO:0016592 mediator complex(GO:0016592)
0.0 0.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 18.0 GO:0031226 intrinsic component of plasma membrane(GO:0031226)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 4.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.1 GO:0097413 Lewy body(GO:0097413)
0.0 0.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 1.4 GO:0055037 recycling endosome(GO:0055037)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.7 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
1.0 6.0 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.5 2.1 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.5 2.5 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.5 2.3 GO:0097643 amylin receptor activity(GO:0097643)
0.4 1.2 GO:0070615 nucleosome-dependent ATPase activity(GO:0070615)
0.4 1.5 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.3 1.1 GO:0019962 interferon receptor activity(GO:0004904) type I interferon receptor activity(GO:0004905) type I interferon binding(GO:0019962)
0.3 4.0 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.3 1.3 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.2 6.0 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 2.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 1.1 GO:0070728 leucine binding(GO:0070728)
0.2 1.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.2 0.7 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.2 1.5 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 8.2 GO:0030507 spectrin binding(GO:0030507)
0.1 1.0 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.1 0.8 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 2.0 GO:0001848 complement binding(GO:0001848)
0.1 2.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 5.3 GO:0005518 collagen binding(GO:0005518)
0.1 1.0 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.2 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.1 1.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 1.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.6 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.6 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.9 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 1.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 1.2 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.6 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 3.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 1.0 GO:0008432 JUN kinase binding(GO:0008432)
0.0 1.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.7 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 3.1 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.5 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 1.0 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 2.5 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.3 GO:0046977 TAP binding(GO:0046977)
0.0 0.1 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.0 0.2 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.1 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 1.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.3 GO:0031402 sodium ion binding(GO:0031402)
0.0 0.2 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 1.7 GO:0017137 Rab GTPase binding(GO:0017137)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.5 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.2 4.0 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 5.3 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.2 7.0 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.1 0.3 ST_TYPE_I_INTERFERON_PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 1.5 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 2.4 PID_IL2_1PATHWAY IL2-mediated signaling events
0.0 3.4 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.8 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 1.3 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 4.6 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.4 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.0 0.3 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.0 PID_RHOA_REG_PATHWAY Regulation of RhoA activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.3 9.4 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 6.0 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.2 3.3 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.2 3.3 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.2 5.0 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.1 1.1 REACTOME_REGULATION_OF_IFNA_SIGNALING Genes involved in Regulation of IFNA signaling
0.1 0.6 REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION Genes involved in Downstream signal transduction
0.1 1.3 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.1 0.8 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.5 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 0.7 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 0.7 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 2.1 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.9 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 1.4 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 2.8 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 2.6 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.2 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 1.2 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 2.3 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.6 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.7 REACTOME_IL1_SIGNALING Genes involved in Interleukin-1 signaling
0.0 1.7 REACTOME_GENERIC_TRANSCRIPTION_PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.3 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter