Motif ID: Crem_Jdp2

Z-value: 0.550

Transcription factors associated with Crem_Jdp2:

Gene SymbolEntrez IDGene Name
Crem ENSMUSG00000063889.10 Crem
Jdp2 ENSMUSG00000034271.9 Jdp2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cremmm10_v2_chr18_-_3281036_3281132-0.305.8e-02Click!
Jdp2mm10_v2_chr12_+_85599388_85599416-0.278.4e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Crem_Jdp2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_23248264 6.586 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr17_+_43952999 3.974 ENSMUST00000177857.1
Rcan2
regulator of calcineurin 2
chr17_+_43953191 3.854 ENSMUST00000044792.4
Rcan2
regulator of calcineurin 2
chr1_-_79440039 3.211 ENSMUST00000049972.4
Scg2
secretogranin II
chr11_-_84525514 3.038 ENSMUST00000018842.7
Lhx1
LIM homeobox protein 1
chr5_-_106458440 2.758 ENSMUST00000086795.6
Barhl2
BarH-like 2 (Drosophila)
chr1_+_74791516 2.534 ENSMUST00000006718.8
Wnt10a
wingless related MMTV integration site 10a
chr11_+_84525669 2.403 ENSMUST00000126072.1
ENSMUST00000128121.1
1500016L03Rik

RIKEN cDNA 1500016L03 gene

chr3_+_125404072 2.232 ENSMUST00000173932.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr11_+_84525647 1.953 ENSMUST00000134800.1
1500016L03Rik
RIKEN cDNA 1500016L03 gene
chr3_+_125404292 1.951 ENSMUST00000144344.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr19_-_5085483 1.838 ENSMUST00000140389.1
ENSMUST00000151413.1
ENSMUST00000077066.7
Tmem151a


transmembrane protein 151A


chr9_-_52679429 1.734 ENSMUST00000098768.2
AI593442
expressed sequence AI593442
chr7_-_137314394 1.697 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
Ebf3



early B cell factor 3



chr7_-_142899985 1.633 ENSMUST00000000219.3
Th
tyrosine hydroxylase
chr16_-_16829276 1.617 ENSMUST00000023468.5
Spag6
sperm associated antigen 6
chr12_+_79130777 1.514 ENSMUST00000021550.6
Arg2
arginase type II
chr5_-_69341699 1.357 ENSMUST00000054095.4
Kctd8
potassium channel tetramerisation domain containing 8
chr2_+_143546144 1.349 ENSMUST00000028905.9
Pcsk2
proprotein convertase subtilisin/kexin type 2
chr8_-_24438937 1.334 ENSMUST00000052622.4
1810011O10Rik
RIKEN cDNA 1810011O10 gene
chr13_+_113035111 1.285 ENSMUST00000180543.1
ENSMUST00000181568.1
ENSMUST00000109244.2
ENSMUST00000181117.1
ENSMUST00000181741.1
Cdc20b




cell division cycle 20B




chr15_+_34238026 1.272 ENSMUST00000022867.3
Laptm4b
lysosomal-associated protein transmembrane 4B
chr7_-_38271310 1.197 ENSMUST00000032585.6
Pop4
processing of precursor 4, ribonuclease P/MRP family, (S. cerevisiae)
chr11_+_64435315 1.181 ENSMUST00000058652.5
Hs3st3a1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
chr11_+_52764634 1.100 ENSMUST00000036796.7
Fstl4
follistatin-like 4
chr18_+_36348653 1.077 ENSMUST00000050584.3
Cystm1
cysteine-rich transmembrane module containing 1
chr9_-_20976762 1.018 ENSMUST00000054197.5
S1pr2
sphingosine-1-phosphate receptor 2
chr5_+_142960343 0.988 ENSMUST00000031565.8
Fscn1
fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)
chrX_-_56598069 0.987 ENSMUST00000059899.2
Mmgt1
membrane magnesium transporter 1
chr11_+_101468164 0.962 ENSMUST00000001347.6
Rnd2
Rho family GTPase 2
chr10_+_44268328 0.923 ENSMUST00000039286.4
Atg5
autophagy related 5
chr1_+_107511489 0.922 ENSMUST00000064916.2
Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr9_-_96478660 0.899 ENSMUST00000057500.4
Rnf7
ring finger protein 7
chr7_+_139389072 0.862 ENSMUST00000106098.1
ENSMUST00000026550.7
Inpp5a

inositol polyphosphate-5-phosphatase A

chr1_+_107511416 0.852 ENSMUST00000009356.4
Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr7_+_79500018 0.852 ENSMUST00000182495.1
ENSMUST00000183043.1
AI854517

expressed sequence AI854517

chr6_-_50566535 0.831 ENSMUST00000161401.1
Cycs
cytochrome c, somatic
chr7_-_142095266 0.828 ENSMUST00000039926.3
Dusp8
dual specificity phosphatase 8
chr4_-_123750236 0.821 ENSMUST00000102636.3
Akirin1
akirin 1
chr4_+_32238713 0.789 ENSMUST00000108180.2
Bach2
BTB and CNC homology 2
chr17_-_26508463 0.783 ENSMUST00000025025.6
Dusp1
dual specificity phosphatase 1
chr14_+_47472628 0.758 ENSMUST00000095941.2
Fbxo34
F-box protein 34
chr17_-_87446854 0.742 ENSMUST00000040440.6
Calm2
calmodulin 2
chr11_-_100939540 0.740 ENSMUST00000127638.1
Stat3
signal transducer and activator of transcription 3
chr11_-_100939357 0.736 ENSMUST00000092671.5
ENSMUST00000103114.1
Stat3

signal transducer and activator of transcription 3

chr14_+_47472547 0.729 ENSMUST00000168833.1
ENSMUST00000163324.1
ENSMUST00000043112.7
Fbxo34


F-box protein 34


chrX_-_167209149 0.728 ENSMUST00000112176.1
Tmsb4x
thymosin, beta 4, X chromosome
chr13_-_64274879 0.725 ENSMUST00000109770.1
Cdc14b
CDC14 cell division cycle 14B
chr9_+_106170918 0.725 ENSMUST00000020490.5
Wdr82
WD repeat domain containing 82
chr1_-_75264195 0.724 ENSMUST00000027404.5
Ptprn
protein tyrosine phosphatase, receptor type, N
chr11_-_100939457 0.713 ENSMUST00000138438.1
Stat3
signal transducer and activator of transcription 3
chrX_-_7188713 0.683 ENSMUST00000004428.7
Clcn5
chloride channel 5
chr11_-_78165521 0.679 ENSMUST00000017530.3
Traf4
TNF receptor associated factor 4
chr2_+_49619277 0.669 ENSMUST00000028102.7
Kif5c
kinesin family member 5C
chr10_+_96616998 0.649 ENSMUST00000038377.7
Btg1
B cell translocation gene 1, anti-proliferative
chr2_+_122738495 0.647 ENSMUST00000005954.8
Bloc1s6
biogenesis of organelles complex-1, subunit 6, pallidin
chr2_+_155276297 0.643 ENSMUST00000029128.3
Map1lc3a
microtubule-associated protein 1 light chain 3 alpha
chr9_+_102718424 0.642 ENSMUST00000156485.1
ENSMUST00000145937.1
ENSMUST00000134483.1
Amotl2


angiomotin-like 2


chr3_+_67374091 0.635 ENSMUST00000077916.5
Mlf1
myeloid leukemia factor 1
chr12_-_86884808 0.625 ENSMUST00000038422.6
Irf2bpl
interferon regulatory factor 2 binding protein-like
chr3_+_67374116 0.623 ENSMUST00000061322.8
Mlf1
myeloid leukemia factor 1
chr7_+_139248477 0.618 ENSMUST00000093993.3
ENSMUST00000172136.1
Pwwp2b

PWWP domain containing 2B

chr18_+_36348739 0.610 ENSMUST00000152804.2
Cystm1
cysteine-rich transmembrane module containing 1
chr5_+_24164963 0.606 ENSMUST00000049887.6
Nupl2
nucleoporin like 2
chr12_-_17176888 0.603 ENSMUST00000170580.1
Kcnf1
potassium voltage-gated channel, subfamily F, member 1
chr11_+_52232183 0.602 ENSMUST00000109072.1
Skp1a
S-phase kinase-associated protein 1A
chr17_+_23679363 0.596 ENSMUST00000024699.2
Cldn6
claudin 6
chr4_-_150652097 0.593 ENSMUST00000117997.1
ENSMUST00000037827.3
Slc45a1

solute carrier family 45, member 1

chr13_-_19395728 0.586 ENSMUST00000039694.7
Stard3nl
STARD3 N-terminal like
chr7_+_79500081 0.576 ENSMUST00000181511.2
ENSMUST00000182937.1
AI854517

expressed sequence AI854517

chr6_-_149188648 0.562 ENSMUST00000095319.3
ENSMUST00000141346.1
ENSMUST00000111535.1
Amn1


antagonist of mitotic exit network 1


chr7_-_144939823 0.561 ENSMUST00000093962.4
Ccnd1
cyclin D1
chr1_-_92473801 0.554 ENSMUST00000027478.6
Ndufa10
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10
chr17_+_72918298 0.544 ENSMUST00000024857.6
Lbh
limb-bud and heart
chr14_-_67072465 0.539 ENSMUST00000089230.5
Ppp2r2a
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform
chr5_+_33018816 0.536 ENSMUST00000019109.7
Ywhah
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr6_-_86669136 0.531 ENSMUST00000001184.7
Mxd1
MAX dimerization protein 1
chr6_+_14901344 0.531 ENSMUST00000115477.1
Foxp2
forkhead box P2
chr7_+_138846335 0.519 ENSMUST00000041097.6
Ppp2r2d
protein phosphatase 2, regulatory subunit B, delta isoform
chr11_+_69324055 0.518 ENSMUST00000102601.3
Trappc1
trafficking protein particle complex 1
chr2_-_36136773 0.517 ENSMUST00000028251.3
Rbm18
RNA binding motif protein 18
chr11_+_69324069 0.508 ENSMUST00000060956.6
ENSMUST00000108662.1
Trappc1

trafficking protein particle complex 1

chr11_+_108682602 0.499 ENSMUST00000106718.3
ENSMUST00000106715.1
ENSMUST00000106724.3
Cep112


centrosomal protein 112


chr11_-_59163281 0.499 ENSMUST00000069631.2
Iba57
IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
chr8_-_106011422 0.490 ENSMUST00000058579.5
Ddx28
DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
chr10_-_102490418 0.478 ENSMUST00000020040.3
Nts
neurotensin
chr14_+_54476100 0.468 ENSMUST00000164766.1
ENSMUST00000164697.1
Rem2

rad and gem related GTP binding protein 2

chr10_-_89686250 0.462 ENSMUST00000092227.5
ENSMUST00000174252.1
Scyl2

SCY1-like 2 (S. cerevisiae)

chr9_+_66713719 0.461 ENSMUST00000085420.5
Car12
carbonic anyhydrase 12
chr1_-_71653162 0.455 ENSMUST00000055226.6
Fn1
fibronectin 1
chr1_-_165236892 0.453 ENSMUST00000043235.5
Tiprl
TIP41, TOR signalling pathway regulator-like (S. cerevisiae)
chr11_-_59163696 0.453 ENSMUST00000137433.1
ENSMUST00000054523.5
Iba57

IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)

chr9_+_66713686 0.452 ENSMUST00000071889.6
Car12
carbonic anyhydrase 12
chr10_+_72654845 0.452 ENSMUST00000020081.4
Zwint
ZW10 interactor
chr1_+_63273261 0.451 ENSMUST00000114132.1
ENSMUST00000126932.1
Zdbf2

zinc finger, DBF-type containing 2

chr8_-_4325096 0.450 ENSMUST00000098950.4
Elavl1
ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R)
chrX_-_48208566 0.447 ENSMUST00000037960.4
Zdhhc9
zinc finger, DHHC domain containing 9
chr16_+_38562821 0.437 ENSMUST00000163948.1
Tmem39a
transmembrane protein 39a
chr2_-_36136602 0.433 ENSMUST00000122456.1
Rbm18
RNA binding motif protein 18
chr5_-_25223153 0.431 ENSMUST00000066954.1
E130116L18Rik
RIKEN cDNA E130116L18 gene
chr11_-_90390895 0.429 ENSMUST00000004051.7
Hlf
hepatic leukemia factor
chr4_+_21931291 0.428 ENSMUST00000029908.7
Faxc
failed axon connections homolog (Drosophila)
chr16_+_38562806 0.427 ENSMUST00000171687.1
ENSMUST00000002924.8
Tmem39a

transmembrane protein 39a

chrX_-_48208870 0.427 ENSMUST00000088935.3
Zdhhc9
zinc finger, DHHC domain containing 9
chr4_+_32238950 0.417 ENSMUST00000037416.6
Bach2
BTB and CNC homology 2
chr9_-_96478596 0.417 ENSMUST00000071301.4
Rnf7
ring finger protein 7
chr8_+_79711792 0.409 ENSMUST00000048147.7
Anapc10
anaphase promoting complex subunit 10
chr6_-_30304513 0.393 ENSMUST00000094543.2
ENSMUST00000102993.3
Ube2h

ubiquitin-conjugating enzyme E2H

chr7_+_99267428 0.391 ENSMUST00000068973.4
ENSMUST00000122101.1
Map6

microtubule-associated protein 6

chr12_+_52097737 0.378 ENSMUST00000040090.9
Nubpl
nucleotide binding protein-like
chr11_-_113751813 0.374 ENSMUST00000053536.4
Cdc42ep4
CDC42 effector protein (Rho GTPase binding) 4
chr6_+_134035691 0.373 ENSMUST00000081028.6
ENSMUST00000111963.1
Etv6

ets variant gene 6 (TEL oncogene)

chr9_-_105395237 0.373 ENSMUST00000140851.1
Nek11
NIMA (never in mitosis gene a)-related expressed kinase 11
chr7_+_138846579 0.368 ENSMUST00000155672.1
Ppp2r2d
protein phosphatase 2, regulatory subunit B, delta isoform
chr11_+_52232009 0.364 ENSMUST00000037324.5
ENSMUST00000166537.1
Skp1a

S-phase kinase-associated protein 1A

chr3_-_146108047 0.363 ENSMUST00000160285.1
Wdr63
WD repeat domain 63
chr9_+_64179289 0.358 ENSMUST00000034965.6
Snapc5
small nuclear RNA activating complex, polypeptide 5
chr4_+_56802337 0.358 ENSMUST00000045368.5
BC026590
cDNA sequence BC026590
chrX_+_143664290 0.356 ENSMUST00000112868.1
Pak3
p21 protein (Cdc42/Rac)-activated kinase 3
chr3_+_31095052 0.355 ENSMUST00000118470.1
ENSMUST00000029194.5
ENSMUST00000123532.1
ENSMUST00000117728.1
Skil



SKI-like



chr17_+_84511832 0.352 ENSMUST00000047206.5
Plekhh2
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr9_+_74861888 0.352 ENSMUST00000056006.9
Onecut1
one cut domain, family member 1
chr7_+_100607410 0.349 ENSMUST00000107048.1
ENSMUST00000032946.3
Rab6a

RAB6A, member RAS oncogene family

chr12_+_72761211 0.349 ENSMUST00000021514.8
Ppm1a
protein phosphatase 1A, magnesium dependent, alpha isoform
chr5_-_93206428 0.340 ENSMUST00000144514.1
Ccni
cyclin I
chr7_+_63444741 0.339 ENSMUST00000058476.7
Otud7a
OTU domain containing 7A
chr14_+_56887795 0.334 ENSMUST00000022511.8
Zmym2
zinc finger, MYM-type 2
chr2_-_3474954 0.333 ENSMUST00000060618.6
Suv39h2
suppressor of variegation 3-9 homolog 2 (Drosophila)
chr7_+_100607660 0.331 ENSMUST00000098252.4
Rab6a
RAB6A, member RAS oncogene family
chr12_-_21417356 0.329 ENSMUST00000103002.1
Ywhaq
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
chr11_+_69323963 0.329 ENSMUST00000102602.1
Trappc1
trafficking protein particle complex 1
chr17_-_27907706 0.328 ENSMUST00000025057.4
Taf11
TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr4_+_8690399 0.323 ENSMUST00000127476.1
Chd7
chromodomain helicase DNA binding protein 7
chr13_-_54688264 0.322 ENSMUST00000150626.1
ENSMUST00000134177.1
Rnf44

ring finger protein 44

chr4_-_132075250 0.322 ENSMUST00000105970.1
ENSMUST00000105975.1
Epb4.1

erythrocyte protein band 4.1

chr3_+_129199919 0.315 ENSMUST00000029657.9
ENSMUST00000106382.4
Pitx2

paired-like homeodomain transcription factor 2

chr6_+_34598530 0.313 ENSMUST00000115027.1
ENSMUST00000115026.1
Cald1

caldesmon 1

chr11_-_76243687 0.312 ENSMUST00000017430.5
Glod4
glyoxalase domain containing 4
chr11_+_52098681 0.312 ENSMUST00000020608.2
Ppp2ca
protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform
chr13_-_58215615 0.311 ENSMUST00000058735.5
ENSMUST00000076454.6
Ubqln1

ubiquilin 1

chr5_-_137530990 0.310 ENSMUST00000132525.1
Gnb2
guanine nucleotide binding protein (G protein), beta 2
chr4_+_141301228 0.308 ENSMUST00000006614.2
Epha2
Eph receptor A2
chr2_+_32095518 0.306 ENSMUST00000057423.5
Ppapdc3
phosphatidic acid phosphatase type 2 domain containing 3
chr12_-_40223149 0.305 ENSMUST00000171553.1
ENSMUST00000001672.5
Ifrd1

interferon-related developmental regulator 1

chr15_-_12321899 0.304 ENSMUST00000180521.1
1810049J17Rik
RIKEN cDNA 1810049J17 gene
chr15_+_12321472 0.302 ENSMUST00000059680.5
Golph3
golgi phosphoprotein 3
chr10_+_128337761 0.301 ENSMUST00000005826.7
Cs
citrate synthase
chr5_-_93206489 0.299 ENSMUST00000058550.8
Ccni
cyclin I
chr8_-_110997764 0.297 ENSMUST00000040416.7
Ddx19a
DEAD (Asp-Glu-Ala-Asp) box polypeptide 19a
chr3_-_36571952 0.295 ENSMUST00000029270.3
Ccna2
cyclin A2
chr11_+_52396414 0.292 ENSMUST00000109057.1
ENSMUST00000036952.4
9530068E07Rik

RIKEN cDNA 9530068E07 gene

chr3_-_138143352 0.289 ENSMUST00000098580.2
Mttp
microsomal triglyceride transfer protein
chr17_-_56476462 0.289 ENSMUST00000067538.5
Ptprs
protein tyrosine phosphatase, receptor type, S
chr7_+_24530645 0.288 ENSMUST00000049020.7
Irgq
immunity-related GTPase family, Q
chr19_+_21272276 0.286 ENSMUST00000025659.4
Zfand5
zinc finger, AN1-type domain 5
chr8_+_45885479 0.283 ENSMUST00000034053.5
Pdlim3
PDZ and LIM domain 3
chr13_-_100744588 0.283 ENSMUST00000078573.4
ENSMUST00000109333.1
Mrps36

mitochondrial ribosomal protein S36

chr5_-_97111565 0.283 ENSMUST00000112969.3
Paqr3
progestin and adipoQ receptor family member III
chr7_-_105744312 0.282 ENSMUST00000141116.1
Taf10
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr8_+_72135247 0.282 ENSMUST00000003575.9
Tpm4
tropomyosin 4
chr6_+_34598500 0.281 ENSMUST00000079391.3
ENSMUST00000142512.1
Cald1

caldesmon 1

chr11_-_88718223 0.272 ENSMUST00000107909.1
Msi2
musashi RNA-binding protein 2
chr13_-_54688065 0.272 ENSMUST00000125871.1
Rnf44
ring finger protein 44
chr3_+_90072641 0.270 ENSMUST00000121503.1
ENSMUST00000119570.1
ENSMUST00000062193.9
Tpm3


tropomyosin 3, gamma


chr6_+_15196949 0.268 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
Foxp2



forkhead box P2



chr7_-_118584669 0.268 ENSMUST00000044195.4
Tmc7
transmembrane channel-like gene family 7
chr2_+_164746028 0.267 ENSMUST00000109327.3
Dnttip1
deoxynucleotidyltransferase, terminal, interacting protein 1
chr12_-_21417591 0.267 ENSMUST00000135088.1
Ywhaq
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
chr2_-_3475027 0.267 ENSMUST00000027956.2
Suv39h2
suppressor of variegation 3-9 homolog 2 (Drosophila)
chr13_-_54688184 0.267 ENSMUST00000150806.1
ENSMUST00000125927.1
Rnf44

ring finger protein 44

chr9_+_109931774 0.266 ENSMUST00000169851.2
Map4
microtubule-associated protein 4
chr9_+_40269273 0.265 ENSMUST00000176185.1
Scn3b
sodium channel, voltage-gated, type III, beta
chr19_-_42129043 0.264 ENSMUST00000018965.3
Avpi1
arginine vasopressin-induced 1
chr9_+_40269202 0.263 ENSMUST00000114956.3
ENSMUST00000049941.5
Scn3b

sodium channel, voltage-gated, type III, beta

chr11_-_52000748 0.263 ENSMUST00000109086.1
Ube2b
ubiquitin-conjugating enzyme E2B
chr10_-_117845935 0.262 ENSMUST00000064667.7
Rap1b
RAS related protein 1b
chr2_-_38926217 0.259 ENSMUST00000076275.4
ENSMUST00000142130.1
Nr6a1

nuclear receptor subfamily 6, group A, member 1

chr12_-_21417526 0.259 ENSMUST00000049531.9
ENSMUST00000155480.1
Ywhaq

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide

chr9_+_59578192 0.256 ENSMUST00000118549.1
ENSMUST00000034840.3
Celf6

CUGBP, Elav-like family member 6

chr8_+_92674826 0.255 ENSMUST00000167261.2
Irx6
Iroquois related homeobox 6 (Drosophila)
chr15_+_25843264 0.255 ENSMUST00000022881.7
Fam134b
family with sequence similarity 134, member B
chr3_-_158036630 0.253 ENSMUST00000121326.1
Srsf11
serine/arginine-rich splicing factor 11
chr1_-_134079114 0.253 ENSMUST00000020692.6
Btg2
B cell translocation gene 2, anti-proliferative
chr2_-_120609283 0.251 ENSMUST00000102496.1
Lrrc57
leucine rich repeat containing 57
chr6_+_124808885 0.249 ENSMUST00000143040.1
ENSMUST00000052727.4
ENSMUST00000130160.1
Spsb2


splA/ryanodine receptor domain and SOCS box containing 2


chr5_+_101765120 0.249 ENSMUST00000031273.8
Cds1
CDP-diacylglycerol synthase 1
chr2_+_120609383 0.245 ENSMUST00000124187.1
Haus2
HAUS augmin-like complex, subunit 2
chr2_+_178141920 0.245 ENSMUST00000103066.3
Phactr3
phosphatase and actin regulator 3
chr10_-_128176568 0.242 ENSMUST00000092033.2
Rbms2
RNA binding motif, single stranded interacting protein 2
chr17_+_34982154 0.242 ENSMUST00000173004.1
Lsm2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr13_-_99516537 0.241 ENSMUST00000064762.4
Map1b
microtubule-associated protein 1B
chr6_-_124464772 0.240 ENSMUST00000008297.4
Clstn3
calsyntenin 3
chr2_+_167777467 0.238 ENSMUST00000139927.1
ENSMUST00000127441.1
Gm14321

predicted gene 14321

chr10_+_72654873 0.238 ENSMUST00000105431.1
ENSMUST00000160337.1
Zwint

ZW10 interactor

chr15_+_59648644 0.238 ENSMUST00000118228.1
Trib1
tribbles homolog 1 (Drosophila)
chr13_+_5861489 0.237 ENSMUST00000000080.6
Klf6
Kruppel-like factor 6
chr4_-_109202217 0.236 ENSMUST00000160774.1
ENSMUST00000030288.7
ENSMUST00000162787.2
Osbpl9


oxysterol binding protein-like 9


chr17_+_34982099 0.234 ENSMUST00000007266.7
Lsm2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr17_-_45573253 0.233 ENSMUST00000165127.1
ENSMUST00000166469.1
ENSMUST00000024739.7
Hsp90ab1


heat shock protein 90 alpha (cytosolic), class B member 1


chr3_+_129199878 0.231 ENSMUST00000174661.2
Pitx2
paired-like homeodomain transcription factor 2

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 6.6 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
1.0 3.0 GO:0072284 cervix development(GO:0060067) metanephric S-shaped body morphogenesis(GO:0072284) anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.6 3.2 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.5 2.2 GO:1902724 positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.4 1.3 GO:0030070 insulin processing(GO:0030070)
0.4 1.3 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.4 7.9 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.4 1.2 GO:0035973 aggrephagy(GO:0035973)
0.4 1.6 GO:0042414 epinephrine metabolic process(GO:0042414)
0.4 1.5 GO:0090467 regulation of amino acid import(GO:0010958) L-arginine import(GO:0043091) arginine import(GO:0090467)
0.3 2.5 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.2 0.9 GO:0060578 extraocular skeletal muscle development(GO:0002074) subthalamic nucleus development(GO:0021763) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.2 1.0 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.2 0.5 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.2 0.5 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931) calcium-independent cell-matrix adhesion(GO:0007161) transforming growth factor-beta secretion(GO:0038044)
0.1 1.0 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 0.7 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 1.1 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.1 0.9 GO:0055064 carbon dioxide transport(GO:0015670) chloride ion homeostasis(GO:0055064)
0.1 1.1 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 0.7 GO:0098964 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.1 1.3 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.1 0.5 GO:1904672 regulation of somatic stem cell population maintenance(GO:1904672)
0.1 0.6 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 0.3 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1 0.8 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1 0.3 GO:0014028 notochord formation(GO:0014028) axial mesoderm morphogenesis(GO:0048319)
0.1 1.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 0.7 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 0.5 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 0.3 GO:0031038 myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519)
0.1 0.3 GO:0071335 hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.1 0.2 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.1 1.0 GO:0006824 cobalt ion transport(GO:0006824)
0.1 0.2 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 0.2 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.1 0.4 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.1 0.6 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.1 0.9 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.2 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1 0.2 GO:0097278 transforming growth factor beta activation(GO:0036363) complement-dependent cytotoxicity(GO:0097278)
0.1 0.5 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 0.8 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 1.4 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 0.2 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.1 0.6 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.1 0.2 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1 0.2 GO:0019046 release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382)
0.1 0.4 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.6 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.1 0.2 GO:1903753 negative regulation of p38MAPK cascade(GO:1903753)
0.1 0.7 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1 0.2 GO:2000850 negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.1 1.0 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.7 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 0.3 GO:0090164 asymmetric Golgi ribbon formation(GO:0090164)
0.1 0.7 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 0.6 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.1 0.5 GO:0060373 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371) regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 0.3 GO:0018377 N-terminal protein myristoylation(GO:0006499) protein myristoylation(GO:0018377)
0.1 0.3 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 0.3 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.1 0.7 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 0.9 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.1 0.6 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 0.2 GO:0097212 cleavage furrow ingression(GO:0036090) lysosomal membrane organization(GO:0097212)
0.1 0.4 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.2 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 2.0 GO:0001709 cell fate determination(GO:0001709)
0.0 0.1 GO:0033566 gamma-tubulin complex localization(GO:0033566)
0.0 1.0 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.3 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 0.2 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.1 GO:0051030 snRNA transport(GO:0051030)
0.0 0.2 GO:0001844 protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:0001844)
0.0 0.2 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 0.1 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.0 0.2 GO:0051661 cortical microtubule organization(GO:0043622) maintenance of centrosome location(GO:0051661)
0.0 1.0 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.1 GO:0060279 positive regulation of ovulation(GO:0060279)
0.0 0.6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.0 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.0 0.5 GO:0006706 steroid catabolic process(GO:0006706)
0.0 0.2 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 0.7 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 0.5 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.1 GO:0045014 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594)
0.0 0.1 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.0 0.1 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.0 0.2 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.7 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.4 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.2 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.5 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.8 GO:0001706 endoderm formation(GO:0001706)
0.0 0.2 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.1 GO:1900864 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0 0.2 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.0 0.2 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.1 GO:1901857 positive regulation of cellular respiration(GO:1901857) regulation of progesterone biosynthetic process(GO:2000182)
0.0 0.2 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.3 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.4 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.0 0.1 GO:0015819 lysine transport(GO:0015819) ornithine transport(GO:0015822)
0.0 0.2 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.0 0.1 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.4 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.2 GO:0032875 regulation of DNA endoreduplication(GO:0032875) DNA endoreduplication(GO:0042023)
0.0 0.3 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.0 0.1 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.1 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.2 GO:0061339 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0 0.1 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.0 0.1 GO:0035864 response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.0 0.4 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.0 0.1 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.3 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:1902741 type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.0 0.1 GO:0030397 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.0 0.7 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.1 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.0 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 0.1 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.1 GO:0060702 negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.1 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.1 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.2 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.4 GO:0003016 respiratory system process(GO:0003016)
0.0 0.1 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.0 0.2 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 0.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.4 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.4 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.1 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.1 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.2 GO:0032460 negative regulation of protein oligomerization(GO:0032460) negative regulation of protein homooligomerization(GO:0032463)
0.0 0.3 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.1 GO:0009644 response to high light intensity(GO:0009644)
0.0 0.2 GO:0030953 astral microtubule organization(GO:0030953)
0.0 0.1 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.0 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.2 GO:0072395 signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422)
0.0 1.8 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.2 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.0 GO:0097343 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.0 0.6 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.0 0.0 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.1 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.3 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.4 1.3 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.3 0.9 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.2 1.0 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.2 0.7 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.2 1.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.2 0.5 GO:0005577 fibrinogen complex(GO:0005577)
0.1 2.4 GO:0031045 dense core granule(GO:0031045)
0.1 0.7 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.7 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 1.4 GO:0030008 TRAPP complex(GO:0030008)
0.1 0.6 GO:0010009 cytoplasmic side of endosome membrane(GO:0010009)
0.1 1.0 GO:0071437 invadopodium(GO:0071437)
0.1 0.6 GO:0030478 actin cap(GO:0030478)
0.1 0.9 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 0.2 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 0.3 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 0.5 GO:0033503 HULC complex(GO:0033503)
0.1 1.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.8 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 0.4 GO:0070652 HAUS complex(GO:0070652)
0.1 0.3 GO:0000235 astral microtubule(GO:0000235)
0.0 0.3 GO:0000125 PCAF complex(GO:0000125)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.0 GO:0061574 ASAP complex(GO:0061574)
0.0 0.6 GO:0044754 secondary lysosome(GO:0005767) autolysosome(GO:0044754)
0.0 0.6 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.3 GO:0001940 male pronucleus(GO:0001940)
0.0 0.5 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.6 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.7 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:1990423 RZZ complex(GO:1990423)
0.0 1.3 GO:0097546 ciliary base(GO:0097546)
0.0 0.1 GO:0097447 dendritic tree(GO:0097447)
0.0 0.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.2 GO:0042581 specific granule(GO:0042581)
0.0 0.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.3 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.1 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 0.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 1.1 GO:0005643 nuclear pore(GO:0005643)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.1 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 2.6 GO:0030141 secretory granule(GO:0030141)
0.0 0.5 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.0 GO:0005769 early endosome(GO:0005769)
0.0 0.1 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.1 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.5 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 7.9 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.6 4.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.4 1.2 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.3 1.6 GO:0035240 dopamine binding(GO:0035240)
0.3 0.9 GO:0019776 Atg8 ligase activity(GO:0019776)
0.3 0.8 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.3 2.3 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.3 1.5 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.2 0.7 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.2 1.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.2 0.7 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.2 1.3 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 3.2 GO:0042056 chemoattractant activity(GO:0042056)
0.1 1.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.1 1.0 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 1.0 GO:0015087 cobalt ion transmembrane transporter activity(GO:0015087)
0.1 1.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.6 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.1 0.2 GO:0002135 CTP binding(GO:0002135)
0.1 1.1 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.1 0.2 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 1.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.5 GO:0045340 mercury ion binding(GO:0045340)
0.1 0.5 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.4 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.2 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 2.2 GO:0005109 frizzled binding(GO:0005109)
0.1 0.6 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.2 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 0.3 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.5 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)
0.1 0.1 GO:0097677 STAT family protein binding(GO:0097677)
0.1 0.9 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.7 GO:0031996 thioesterase binding(GO:0031996)
0.1 0.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.2 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.0 0.6 GO:0001618 virus receptor activity(GO:0001618)
0.0 8.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.0 GO:0097602 cullin family protein binding(GO:0097602)
0.0 1.5 GO:0005112 Notch binding(GO:0005112)
0.0 2.6 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.6 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 1.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.7 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.2 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.2 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.2 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.9 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.7 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 1.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0032564 dATP binding(GO:0032564)
0.0 0.2 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.2 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.1 GO:0070012 oligopeptidase activity(GO:0070012)
0.0 0.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.2 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.3 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 1.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.8 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0016004 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 1.7 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 1.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.3 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.6 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 1.6 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0015643 toxic substance binding(GO:0015643)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.9 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 2.2 ST_STAT3_PATHWAY STAT3 Pathway
0.1 3.0 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 0.9 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 2.0 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.2 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.6 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.0 3.4 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.5 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.2 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.3 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.0 0.2 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.8 PID_HIV_NEF_PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.6 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.3 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.0 0.4 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.0 0.2 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 0.8 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 PID_MYC_PATHWAY C-MYC pathway
0.0 0.3 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.4 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 0.2 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.1 1.6 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.1 5.5 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 1.3 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 0.7 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 1.8 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.7 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 2.9 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.7 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.2 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.0 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.2 REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.3 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.3 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.7 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.8 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.3 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.4 REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.9 REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.7 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.3 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.6 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.1 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.5 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.6 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.4 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.2 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.1 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.3 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.5 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.4 REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.5 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing