Motif ID: Nr2f6

Z-value: 0.591


Transcription factors associated with Nr2f6:

Gene SymbolEntrez IDGene Name
Nr2f6 ENSMUSG00000002393.8 Nr2f6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr2f6mm10_v2_chr8_-_71381907_71381977-0.251.2e-01Click!


Activity profile for motif Nr2f6.

activity profile for motif Nr2f6


Sorted Z-values histogram for motif Nr2f6

Sorted Z-values for motif Nr2f6



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr2f6

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_138847579 2.668 ENSMUST00000093486.3
ENSMUST00000046870.6
Lhx9

LIM homeobox protein 9

chr4_-_41697040 2.508 ENSMUST00000102962.3
ENSMUST00000084701.5
Cntfr

ciliary neurotrophic factor receptor

chr4_+_85205417 1.936 ENSMUST00000030212.8
ENSMUST00000107189.1
ENSMUST00000107184.1
Sh3gl2


SH3-domain GRB2-like 2


chr4_-_97778042 1.901 ENSMUST00000146447.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr19_+_47228804 1.801 ENSMUST00000111807.3
Neurl1a
neuralized homolog 1A (Drosophila)
chr6_+_83156401 1.698 ENSMUST00000032106.4
1700003E16Rik
RIKEN cDNA 1700003E16 gene
chr13_-_24761861 1.654 ENSMUST00000006898.3
ENSMUST00000110382.2
Gmnn

geminin

chr9_+_109051153 1.645 ENSMUST00000155541.1
ENSMUST00000120305.1
ENSMUST00000154113.1
ENSMUST00000128976.1
ENSMUST00000135942.1
ENSMUST00000143754.1
Shisa5





shisa homolog 5 (Xenopus laevis)





chr4_+_118409331 1.383 ENSMUST00000084319.4
ENSMUST00000106384.3
ENSMUST00000126089.1
ENSMUST00000073881.1
ENSMUST00000019229.8
ENSMUST00000144577.1
Med8





mediator of RNA polymerase II transcription, subunit 8 homolog (yeast)





chr4_+_85205120 1.356 ENSMUST00000107188.3
Sh3gl2
SH3-domain GRB2-like 2
chr13_-_73328442 1.278 ENSMUST00000022097.5
Ndufs6
NADH dehydrogenase (ubiquinone) Fe-S protein 6
chr3_-_89418287 1.265 ENSMUST00000029679.3
Cks1b
CDC28 protein kinase 1b
chr16_-_4624984 1.251 ENSMUST00000014445.6
Pam16
presequence translocase-asssociated motor 16 homolog (S. cerevisiae)
chr11_+_101442440 1.214 ENSMUST00000107249.1
Rpl27
ribosomal protein L27
chr15_+_89532816 1.147 ENSMUST00000167173.1
Shank3
SH3/ankyrin domain gene 3
chr17_-_35132050 1.135 ENSMUST00000025249.6
Apom
apolipoprotein M
chr10_+_43524080 1.131 ENSMUST00000057649.6
Gm9803
predicted gene 9803
chr15_-_95528702 1.121 ENSMUST00000166170.1
Nell2
NEL-like 2
chr10_-_35711891 1.103 ENSMUST00000080898.2
Amd2
S-adenosylmethionine decarboxylase 2
chr11_+_101442298 1.100 ENSMUST00000077856.6
Rpl27
ribosomal protein L27
chr6_+_86365673 1.004 ENSMUST00000071492.7
Fam136a
family with sequence similarity 136, member A
chr7_-_89941084 0.953 ENSMUST00000075010.4
ENSMUST00000153470.1
l7Rn6

lethal, Chr 7, Rinchik 6

chr7_+_3617357 0.951 ENSMUST00000076657.4
ENSMUST00000108644.1
Ndufa3

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3

chr11_+_32283511 0.939 ENSMUST00000093209.3
Hba-a1
hemoglobin alpha, adult chain 1
chr9_-_86695897 0.905 ENSMUST00000034989.8
Me1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr7_-_89941196 0.901 ENSMUST00000117354.1
l7Rn6
lethal, Chr 7, Rinchik 6
chr10_-_93589621 0.894 ENSMUST00000020203.6
Snrpf
small nuclear ribonucleoprotein polypeptide F
chr15_-_81871883 0.871 ENSMUST00000023117.8
Phf5a
PHD finger protein 5A
chr8_+_71469186 0.843 ENSMUST00000124745.1
ENSMUST00000138892.1
ENSMUST00000147642.1
Dda1


DET1 and DDB1 associated 1


chr3_+_121967822 0.819 ENSMUST00000137089.1
Arhgap29
Rho GTPase activating protein 29
chr14_+_57798637 0.804 ENSMUST00000111267.1
Sap18
Sin3-associated polypeptide 18
chr5_+_134176358 0.786 ENSMUST00000180674.1
B230377A18Rik
RIKEN cDNA B230377A18 gene
chr9_-_21073494 0.779 ENSMUST00000010348.5
Fdx1l
ferredoxin 1-like
chr7_-_30232186 0.757 ENSMUST00000006254.5
Tbcb
tubulin folding cofactor B
chr4_-_11076160 0.754 ENSMUST00000058183.8
Ndufaf6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr13_+_43370710 0.747 ENSMUST00000066804.4
Sirt5
sirtuin 5
chr14_+_57798620 0.744 ENSMUST00000111268.1
Sap18
Sin3-associated polypeptide 18
chr6_+_124712279 0.732 ENSMUST00000004375.9
Phb2
prohibitin 2
chr3_-_8923796 0.715 ENSMUST00000042148.5
Mrps28
mitochondrial ribosomal protein S28
chr11_+_116198853 0.701 ENSMUST00000021130.6
Ten1
TEN1 telomerase capping complex subunit
chr10_+_93589413 0.677 ENSMUST00000181835.1
4933408J17Rik
RIKEN cDNA 4933408J17 gene
chr5_-_24902315 0.645 ENSMUST00000131486.1
Prkag2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr7_+_30232310 0.644 ENSMUST00000108193.1
ENSMUST00000108192.1
Polr2i

polymerase (RNA) II (DNA directed) polypeptide I

chr16_-_18248697 0.612 ENSMUST00000115645.3
Ranbp1
RAN binding protein 1
chr9_-_22135675 0.605 ENSMUST00000165735.1
Acp5
acid phosphatase 5, tartrate resistant
chr1_+_74284930 0.597 ENSMUST00000113805.1
ENSMUST00000027370.6
ENSMUST00000087226.4
Pnkd


paroxysmal nonkinesiogenic dyskinesia


chr19_-_44545836 0.586 ENSMUST00000111985.1
ENSMUST00000063632.7
Sec31b

Sec31 homolog B (S. cerevisiae)

chr7_+_98494222 0.576 ENSMUST00000165205.1
Lrrc32
leucine rich repeat containing 32
chr7_+_31059342 0.574 ENSMUST00000039775.7
Lgi4
leucine-rich repeat LGI family, member 4
chr15_-_27630644 0.573 ENSMUST00000059662.7
Fam105b
family with sequence similarity 105, member B
chr10_-_67548944 0.539 ENSMUST00000075686.4
Ado
2-aminoethanethiol (cysteamine) dioxygenase
chr7_+_43444104 0.529 ENSMUST00000004729.3
Etfb
electron transferring flavoprotein, beta polypeptide
chr10_+_128747850 0.519 ENSMUST00000163377.2
Wibg
within bgcn homolog (Drosophila)
chr6_+_113237843 0.508 ENSMUST00000113146.2
Mtmr14
myotubularin related protein 14
chr9_+_21002737 0.507 ENSMUST00000003386.5
Mrpl4
mitochondrial ribosomal protein L4
chr7_+_64501687 0.507 ENSMUST00000032732.8
Apba2
amyloid beta (A4) precursor protein-binding, family A, member 2
chr7_+_38183217 0.477 ENSMUST00000165308.1
1600014C10Rik
RIKEN cDNA 1600014C10 gene
chr7_-_28766469 0.456 ENSMUST00000085851.5
ENSMUST00000032815.4
Nfkbib

nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta

chr17_-_35910032 0.453 ENSMUST00000141662.1
ENSMUST00000056034.6
ENSMUST00000077494.6
ENSMUST00000149277.1
ENSMUST00000061052.5
Atat1




alpha tubulin acetyltransferase 1




chr10_-_119240006 0.450 ENSMUST00000020315.6
Cand1
cullin associated and neddylation disassociated 1
chr5_+_36464998 0.447 ENSMUST00000031099.3
Grpel1
GrpE-like 1, mitochondrial
chr1_+_172499948 0.446 ENSMUST00000111230.1
Tagln2
transgelin 2
chr1_-_74284636 0.431 ENSMUST00000178235.1
ENSMUST00000006462.7
Aamp

angio-associated migratory protein

chr5_-_31202215 0.424 ENSMUST00000176245.1
ENSMUST00000177310.1
ENSMUST00000114590.1
Zfp513


zinc finger protein 513


chr19_-_12501996 0.421 ENSMUST00000045521.7
Dtx4
deltex 4 homolog (Drosophila)
chr2_+_25242929 0.417 ENSMUST00000114355.1
ENSMUST00000060818.1
Rnf208

ring finger protein 208

chr18_+_74779190 0.391 ENSMUST00000041053.9
Acaa2
acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase)
chr14_+_122534305 0.379 ENSMUST00000154206.1
ENSMUST00000038374.6
ENSMUST00000135578.1
Pcca


propionyl-Coenzyme A carboxylase, alpha polypeptide


chr4_-_103215147 0.377 ENSMUST00000150285.1
Slc35d1
solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1
chr5_-_137741601 0.377 ENSMUST00000119498.1
ENSMUST00000061789.7
Nyap1

neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1

chr16_+_4684070 0.371 ENSMUST00000060067.5
ENSMUST00000115854.3
Dnaja3

DnaJ (Hsp40) homolog, subfamily A, member 3

chr9_-_44767792 0.371 ENSMUST00000034607.9
Arcn1
archain 1
chr2_+_59160838 0.364 ENSMUST00000102754.4
ENSMUST00000168631.1
ENSMUST00000123908.1
Pkp4


plakophilin 4


chr10_-_14705459 0.363 ENSMUST00000149485.1
ENSMUST00000154132.1
Vta1

Vps20-associated 1 homolog (S. cerevisiae)

chr13_-_59769751 0.352 ENSMUST00000057115.6
Isca1
iron-sulfur cluster assembly 1 homolog (S. cerevisiae)
chr7_+_79500018 0.352 ENSMUST00000182495.1
ENSMUST00000183043.1
AI854517

expressed sequence AI854517

chr3_-_115888086 0.350 ENSMUST00000067500.5
A930005H10Rik
RIKEN cDNA A930005H10 gene
chr10_+_78574492 0.343 ENSMUST00000105384.3
Ilvbl
ilvB (bacterial acetolactate synthase)-like
chr14_+_57798156 0.335 ENSMUST00000128764.1
Sap18
Sin3-associated polypeptide 18
chr1_+_74506044 0.314 ENSMUST00000087215.5
Rqcd1
rcd1 (required for cell differentiation) homolog 1 (S. pombe)
chr6_+_85431970 0.309 ENSMUST00000045693.7
Smyd5
SET and MYND domain containing 5
chr4_-_137048695 0.308 ENSMUST00000049583.7
Zbtb40
zinc finger and BTB domain containing 40
chr7_+_45896941 0.292 ENSMUST00000069772.7
ENSMUST00000107716.1
Tmem143

transmembrane protein 143

chr14_+_121878591 0.289 ENSMUST00000039803.5
Ubac2
ubiquitin associated domain containing 2
chr3_+_4211716 0.286 ENSMUST00000170943.1
Gm8775
predicted gene 8775
chr7_+_45897429 0.274 ENSMUST00000140243.1
Tmem143
transmembrane protein 143
chr2_+_164805082 0.259 ENSMUST00000052107.4
Zswim3
zinc finger SWIM-type containing 3
chr11_+_68968107 0.257 ENSMUST00000102606.3
ENSMUST00000018884.5
Slc25a35

solute carrier family 25, member 35

chr9_+_108662098 0.256 ENSMUST00000035222.5
Slc25a20
solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20
chr2_+_91082362 0.227 ENSMUST00000169852.1
Spi1
spleen focus forming virus (SFFV) proviral integration oncogene
chr18_+_63708689 0.225 ENSMUST00000072726.5
Wdr7
WD repeat domain 7
chr3_+_138374121 0.221 ENSMUST00000171054.1
Adh6-ps1
alcohol dehydrogenase 6 (class V), pseudogene 1
chr1_-_171360798 0.219 ENSMUST00000061878.4
Klhdc9
kelch domain containing 9
chr9_+_108460518 0.217 ENSMUST00000061209.5
Ccdc71
coiled-coil domain containing 71
chr19_-_47536997 0.217 ENSMUST00000182808.1
ENSMUST00000049369.9
Obfc1

oligonucleotide/oligosaccharide-binding fold containing 1

chr14_+_57798182 0.190 ENSMUST00000111269.1
Sap18
Sin3-associated polypeptide 18
chr7_+_79500081 0.184 ENSMUST00000181511.2
ENSMUST00000182937.1
AI854517

expressed sequence AI854517

chr15_-_100422991 0.175 ENSMUST00000138843.1
ENSMUST00000023774.5
Slc11a2

solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2

chr2_-_164804876 0.170 ENSMUST00000103094.4
ENSMUST00000017451.6
Acot8

acyl-CoA thioesterase 8

chr4_+_97777606 0.151 ENSMUST00000075448.6
ENSMUST00000092532.6
Nfia

nuclear factor I/A

chr9_+_108392820 0.149 ENSMUST00000035234.4
1700102P08Rik
RIKEN cDNA 1700102P08 gene
chr10_-_22731918 0.143 ENSMUST00000095794.3
Tbpl1
TATA box binding protein-like 1
chr4_-_130174691 0.135 ENSMUST00000132545.2
ENSMUST00000175992.1
ENSMUST00000105999.2
Tinagl1


tubulointerstitial nephritis antigen-like 1


chr5_-_31697598 0.134 ENSMUST00000031018.7
Rbks
ribokinase
chr11_-_84870812 0.120 ENSMUST00000168434.1
Ggnbp2
gametogenetin binding protein 2
chr1_+_63176818 0.112 ENSMUST00000129339.1
Eef1b2
eukaryotic translation elongation factor 1 beta 2
chr5_+_31697665 0.111 ENSMUST00000080598.7
Bre
brain and reproductive organ-expressed protein
chr11_+_4986824 0.107 ENSMUST00000009234.9
ENSMUST00000109897.1
Ap1b1

adaptor protein complex AP-1, beta 1 subunit

chr3_+_115888139 0.104 ENSMUST00000106505.1
ENSMUST00000043342.9
Dph5

DPH5 homolog (S. cerevisiae)

chr15_-_76009440 0.098 ENSMUST00000170153.1
Fam83h
family with sequence similarity 83, member H
chr13_-_55571118 0.097 ENSMUST00000021957.6
Fam193b
family with sequence similarity 193, member B
chr19_-_21472552 0.095 ENSMUST00000087600.3
Gda
guanine deaminase
chr4_-_117682233 0.083 ENSMUST00000102687.3
Dmap1
DNA methyltransferase 1-associated protein 1
chr12_+_55155104 0.074 ENSMUST00000110708.2
Srp54b
signal recognition particle 54B
chr6_-_137649211 0.072 ENSMUST00000134630.1
ENSMUST00000058210.6
ENSMUST00000111878.1
Eps8


epidermal growth factor receptor pathway substrate 8


chr5_+_30921556 0.063 ENSMUST00000031053.8
Khk
ketohexokinase
chr6_-_83156393 0.059 ENSMUST00000153148.1
ENSMUST00000125894.1
Wdr54

WD repeat domain 54

chr12_-_93929102 0.054 ENSMUST00000180321.1
Gm9726
predicted gene 9726
chr19_-_6921804 0.052 ENSMUST00000025906.4
Esrra
estrogen related receptor, alpha
chr1_+_180726019 0.051 ENSMUST00000027780.4
Acbd3
acyl-Coenzyme A binding domain containing 3
chr19_+_10001669 0.049 ENSMUST00000121418.1
Rab3il1
RAB3A interacting protein (rabin3)-like 1
chr19_-_3912711 0.041 ENSMUST00000075092.6
Ndufs8
NADH dehydrogenase (ubiquinone) Fe-S protein 8
chr3_-_95133989 0.040 ENSMUST00000172572.2
ENSMUST00000173462.2
Scnm1

sodium channel modifier 1

chr2_+_25242227 0.030 ENSMUST00000154498.1
Rnf208
ring finger protein 208
chr4_+_97777780 0.029 ENSMUST00000107062.2
ENSMUST00000052018.5
ENSMUST00000107057.1
Nfia


nuclear factor I/A


chr12_-_55080098 0.018 ENSMUST00000021406.5
2700097O09Rik
RIKEN cDNA 2700097O09 gene
chr2_+_75832168 0.014 ENSMUST00000047232.7
ENSMUST00000111952.2
Agps

alkylglycerone phosphate synthase

chr11_-_84870712 0.013 ENSMUST00000170741.1
ENSMUST00000172405.1
ENSMUST00000100686.3
ENSMUST00000108081.2
Ggnbp2



gametogenetin binding protein 2



chr2_+_158028687 0.009 ENSMUST00000109518.1
ENSMUST00000029180.7
Rprd1b

regulation of nuclear pre-mRNA domain containing 1B

chr11_-_84870646 0.001 ENSMUST00000018547.2
Ggnbp2
gametogenetin binding protein 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.7 GO:0035262 gonad morphogenesis(GO:0035262)
0.6 2.5 GO:0003360 brainstem development(GO:0003360)
0.5 3.3 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.4 1.1 GO:0050748 negative regulation of lipoprotein metabolic process(GO:0050748)
0.4 1.1 GO:0006597 spermine biosynthetic process(GO:0006597)
0.3 2.9 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.2 0.6 GO:0001193 maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193)
0.2 0.9 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.2 1.9 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.2 0.6 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 0.4 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.1 0.9 GO:0080184 response to stilbenoid(GO:0035634) response to phenylpropanoid(GO:0080184)
0.1 1.3 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 0.3 GO:0071929 alpha-tubulin acetylation(GO:0071929) positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.1 0.6 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 0.4 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.1 0.5 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1 1.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.4 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.6 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 0.6 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 0.4 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.1 0.4 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 1.7 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.2 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.4 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.7 GO:0010566 regulation of ketone biosynthetic process(GO:0010566)
0.0 0.3 GO:0015879 carnitine transport(GO:0015879)
0.0 0.1 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.0 0.2 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.0 0.4 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 2.4 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 0.1 GO:0006014 D-ribose metabolic process(GO:0006014)
0.0 0.1 GO:0046098 guanine metabolic process(GO:0046098)
0.0 0.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.3 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 1.6 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.1 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 1.3 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.9 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.6 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.1 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.0 0.5 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.2 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.6 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.4 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 2.3 GO:0006364 rRNA processing(GO:0006364)
0.0 0.4 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.2 GO:0072189 ureter development(GO:0072189)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.6 1.7 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.3 1.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.2 0.9 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.2 2.1 GO:0061574 ASAP complex(GO:0061574)
0.2 0.9 GO:0034715 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
0.1 0.5 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.1 0.7 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.1 0.9 GO:0005686 U2 snRNP(GO:0005686)
0.1 0.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 2.1 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.8 GO:0097440 apical dendrite(GO:0097440)
0.0 0.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.6 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 1.4 GO:0016592 mediator complex(GO:0016592)
0.0 0.6 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 2.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.4 GO:0030057 desmosome(GO:0030057)
0.0 0.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 1.1 GO:0060170 ciliary membrane(GO:0060170)
0.0 1.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.7 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.6 GO:0030120 vesicle coat(GO:0030120)
0.0 3.3 GO:0005769 early endosome(GO:0005769)
0.0 0.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.5 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.3 1.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.3 0.9 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.3 1.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.3 1.1 GO:0019808 polyamine binding(GO:0019808)
0.2 0.9 GO:0031720 haptoglobin binding(GO:0031720)
0.1 0.4 GO:0004658 propionyl-CoA carboxylase activity(GO:0004658)
0.1 0.6 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 0.6 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 0.6 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 0.3 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.1 0.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.4 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.7 GO:0070403 NAD+ binding(GO:0070403)
0.0 1.6 GO:0050699 WW domain binding(GO:0050699)
0.0 0.5 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.3 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.5 GO:0052744 phosphatidylinositol-3-phosphatase activity(GO:0004438) phosphatidylinositol monophosphate phosphatase activity(GO:0052744)
0.0 1.0 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.2 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 1.4 GO:0045182 translation regulator activity(GO:0045182)
0.0 0.6 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.4 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.1 GO:0004454 ketohexokinase activity(GO:0004454)
0.0 1.7 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.7 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 2.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.1 GO:0016209 antioxidant activity(GO:0016209)
0.0 1.1 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.6 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.4 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 1.4 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.5 GO:0009055 electron carrier activity(GO:0009055)
0.0 0.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.3 GO:0008168 methyltransferase activity(GO:0008168)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.3 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 1.3 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 2.1 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.5 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.0 1.8 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.8 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.5 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.3 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 1.7 REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.1 0.9 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.6 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.8 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.4 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 2.7 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 0.6 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 1.3 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 1.4 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.4 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 2.3 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 0.5 REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.3 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 2.1 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.5 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.4 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.2 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.4 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.3 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA