Motif ID: Zfp691

Z-value: 0.416


Transcription factors associated with Zfp691:

Gene SymbolEntrez IDGene Name
Zfp691 ENSMUSG00000045268.7 Zfp691

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zfp691mm10_v2_chr4_-_119174178_119174221-0.231.5e-01Click!


Activity profile for motif Zfp691.

activity profile for motif Zfp691


Sorted Z-values histogram for motif Zfp691

Sorted Z-values for motif Zfp691



Network of associatons between targets according to the STRING database.



First level regulatory network of Zfp691

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_28863831 1.083 ENSMUST00000138272.1
Lgals7
lectin, galactose binding, soluble 7
chr9_-_58202281 1.075 ENSMUST00000163897.1
Islr2
immunoglobulin superfamily containing leucine-rich repeat 2
chr5_+_128601106 0.881 ENSMUST00000117102.2
Fzd10
frizzled homolog 10 (Drosophila)
chr3_-_33143227 0.828 ENSMUST00000108219.1
Pex5l
peroxisomal biogenesis factor 5-like
chr10_+_81183263 0.776 ENSMUST00000047665.6
Dapk3
death-associated protein kinase 3
chr3_-_33143025 0.750 ENSMUST00000108226.1
Pex5l
peroxisomal biogenesis factor 5-like
chr8_+_72319033 0.703 ENSMUST00000067912.7
Klf2
Kruppel-like factor 2 (lung)
chr9_-_108452377 0.674 ENSMUST00000035232.7
Klhdc8b
kelch domain containing 8B
chr10_-_86732409 0.634 ENSMUST00000070435.4
Fabp3-ps1
fatty acid binding protein 3, muscle and heart, pseudogene 1
chr8_+_88521344 0.621 ENSMUST00000034086.5
Nkd1
naked cuticle 1 homolog (Drosophila)
chr6_+_134640940 0.616 ENSMUST00000062755.8
Loh12cr1
loss of heterozygosity, 12, chromosomal region 1 homolog (human)
chr1_-_138856819 0.613 ENSMUST00000112025.1
2310009B15Rik
RIKEN cDNA 2310009B15 gene
chr9_+_62858085 0.610 ENSMUST00000034777.6
ENSMUST00000163820.1
Calml4

calmodulin-like 4

chr2_+_181715005 0.605 ENSMUST00000071585.3
ENSMUST00000148334.1
ENSMUST00000108763.1
Oprl1


opioid receptor-like 1


chr9_-_103761820 0.596 ENSMUST00000049452.8
Tmem108
transmembrane protein 108
chr9_-_21067093 0.567 ENSMUST00000115494.2
Zglp1
zinc finger, GATA-like protein 1
chr6_-_24515036 0.567 ENSMUST00000052277.4
Iqub
IQ motif and ubiquitin domain containing
chr7_-_45061706 0.509 ENSMUST00000107832.1
Prrg2
proline-rich Gla (G-carboxyglutamic acid) polypeptide 2
chr9_-_106887000 0.492 ENSMUST00000055843.7
Rbm15b
RNA binding motif protein 15B
chr11_-_75422586 0.484 ENSMUST00000138661.1
ENSMUST00000000769.7
Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr13_-_55528511 0.446 ENSMUST00000047877.4
Dok3
docking protein 3
chr4_-_129623870 0.435 ENSMUST00000106035.1
ENSMUST00000150357.1
ENSMUST00000030586.8
Ccdc28b


coiled coil domain containing 28B


chr3_-_92429403 0.423 ENSMUST00000047300.7
Gm9774
predicted pseudogene 9774
chr1_+_134193432 0.399 ENSMUST00000038445.6
Mybph
myosin binding protein H
chr7_-_45061651 0.392 ENSMUST00000007981.3
ENSMUST00000107831.1
Prrg2

proline-rich Gla (G-carboxyglutamic acid) polypeptide 2

chr2_+_29802626 0.387 ENSMUST00000080065.2
Slc27a4
solute carrier family 27 (fatty acid transporter), member 4
chr15_+_44196135 0.382 ENSMUST00000038856.6
ENSMUST00000110289.3
Trhr

thyrotropin releasing hormone receptor

chr2_+_26591423 0.378 ENSMUST00000152988.2
ENSMUST00000149789.1
Egfl7

EGF-like domain 7

chr9_+_50603892 0.372 ENSMUST00000044051.4
Timm8b
translocase of inner mitochondrial membrane 8B
chr10_+_81183000 0.362 ENSMUST00000178422.1
Dapk3
death-associated protein kinase 3
chr10_-_112928974 0.361 ENSMUST00000099276.2
Atxn7l3b
ataxin 7-like 3B
chr10_+_60003321 0.340 ENSMUST00000164083.2
Ascc1
activating signal cointegrator 1 complex subunit 1
chr2_-_155729359 0.331 ENSMUST00000040833.4
Edem2
ER degradation enhancer, mannosidase alpha-like 2
chr14_-_20348040 0.329 ENSMUST00000022344.2
Ecd
ecdysoneless homolog (Drosophila)
chr16_+_32608920 0.317 ENSMUST00000023486.8
Tfrc
transferrin receptor
chr2_-_10130638 0.311 ENSMUST00000042290.7
Itih2
inter-alpha trypsin inhibitor, heavy chain 2
chr4_+_126046903 0.307 ENSMUST00000030675.7
Mrps15
mitochondrial ribosomal protein S15
chr3_+_133338936 0.259 ENSMUST00000150386.1
ENSMUST00000125858.1
Ppa2

pyrophosphatase (inorganic) 2

chr13_+_55622999 0.258 ENSMUST00000021963.4
Caml
calcium modulating ligand
chr19_+_11516473 0.256 ENSMUST00000163078.1
Ms4a6b
membrane-spanning 4-domains, subfamily A, member 6B
chr16_-_32165454 0.254 ENSMUST00000115163.3
ENSMUST00000144345.1
ENSMUST00000143682.1
ENSMUST00000115165.3
ENSMUST00000099991.4
ENSMUST00000130410.1
Nrros





negative regulator of reactive oxygen species





chr13_+_53525703 0.252 ENSMUST00000081132.4
Gm5449
predicted pseudogene 5449
chr15_-_83555681 0.248 ENSMUST00000061882.8
Mcat
malonyl CoA:ACP acyltransferase (mitochondrial)
chr11_-_120467414 0.246 ENSMUST00000076921.6
Arl16
ADP-ribosylation factor-like 16
chr2_-_65529275 0.244 ENSMUST00000126837.1
Scn3a
sodium channel, voltage-gated, type III, alpha
chr12_+_86678685 0.240 ENSMUST00000021681.3
Vash1
vasohibin 1
chr3_-_62605140 0.232 ENSMUST00000058535.5
Gpr149
G protein-coupled receptor 149
chr4_+_129189760 0.231 ENSMUST00000106054.2
ENSMUST00000001365.2
Yars

tyrosyl-tRNA synthetase

chr3_-_67515487 0.218 ENSMUST00000178314.1
ENSMUST00000054825.4
Rarres1

retinoic acid receptor responder (tazarotene induced) 1

chr6_-_34878006 0.209 ENSMUST00000115006.1
ENSMUST00000055097.4
ENSMUST00000115007.2
3110062M04Rik


RIKEN cDNA 3110062M04 gene


chrX_-_101268218 0.208 ENSMUST00000033664.7
Il2rg
interleukin 2 receptor, gamma chain
chr7_+_143069249 0.208 ENSMUST00000060433.3
ENSMUST00000133410.2
ENSMUST00000105920.1
ENSMUST00000177841.1
ENSMUST00000147995.1
ENSMUST00000137856.1
Tssc4





tumor-suppressing subchromosomal transferable fragment 4





chr8_-_124569696 0.190 ENSMUST00000063278.6
Agt
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr13_-_60897439 0.189 ENSMUST00000171347.1
ENSMUST00000021884.8
Ctla2b

cytotoxic T lymphocyte-associated protein 2 beta

chr16_+_90386382 0.176 ENSMUST00000065856.6
Hunk
hormonally upregulated Neu-associated kinase
chr8_+_3621529 0.170 ENSMUST00000156380.2
Pet100
PET100 homolog (S. cerevisiae)
chr8_+_69808672 0.161 ENSMUST00000036074.8
ENSMUST00000123453.1
Gmip

Gem-interacting protein

chr5_+_95956916 0.161 ENSMUST00000023840.5
Cxcl13
chemokine (C-X-C motif) ligand 13
chr13_-_34130345 0.156 ENSMUST00000075774.3
Tubb2b
tubulin, beta 2B class IIB
chr15_-_12592556 0.155 ENSMUST00000075317.5
Pdzd2
PDZ domain containing 2
chr14_+_20348159 0.143 ENSMUST00000090503.4
ENSMUST00000090499.5
ENSMUST00000037698.5
ENSMUST00000051915.6
Fam149b



family with sequence similarity 149, member B



chr6_+_28475101 0.141 ENSMUST00000168362.1
Snd1
staphylococcal nuclease and tudor domain containing 1
chr1_+_51289106 0.138 ENSMUST00000051572.6
Sdpr
serum deprivation response
chr2_+_24962400 0.137 ENSMUST00000028351.3
Dph7
diphthamine biosynethesis 7
chr8_-_77517898 0.131 ENSMUST00000076316.4
Arhgap10
Rho GTPase activating protein 10
chr11_-_116694802 0.128 ENSMUST00000079545.5
St6galnac2
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr10_+_94576254 0.126 ENSMUST00000117929.1
Tmcc3
transmembrane and coiled coil domains 3
chr10_-_60002993 0.123 ENSMUST00000182116.1
Anapc16
anaphase promoting complex subunit 16
chr10_-_81183849 0.119 ENSMUST00000056086.4
4930442H23Rik
RIKEN cDNA 4930442H23 gene
chr15_-_76723814 0.118 ENSMUST00000036247.8
C030006K11Rik
RIKEN cDNA C030006K11 gene
chr2_-_131352857 0.103 ENSMUST00000059372.4
Rnf24
ring finger protein 24
chr9_+_50617516 0.101 ENSMUST00000141366.1
Pih1d2
PIH1 domain containing 2
chr10_-_93891141 0.100 ENSMUST00000180840.1
Metap2
methionine aminopeptidase 2
chr8_+_123235086 0.094 ENSMUST00000181432.1
4933417D19Rik
RIKEN cDNA 4933417D19 gene
chr14_-_70323783 0.094 ENSMUST00000151011.1
Slc39a14
solute carrier family 39 (zinc transporter), member 14
chr4_+_124714776 0.089 ENSMUST00000030734.4
Sf3a3
splicing factor 3a, subunit 3
chr8_-_22805596 0.088 ENSMUST00000163739.1
Ap3m2
adaptor-related protein complex 3, mu 2 subunit
chr18_-_56975333 0.085 ENSMUST00000139243.2
ENSMUST00000025488.8
C330018D20Rik

RIKEN cDNA C330018D20 gene

chr9_-_50617428 0.084 ENSMUST00000131351.1
ENSMUST00000171462.1
AU019823

expressed sequence AU019823

chr9_+_27299205 0.081 ENSMUST00000115247.1
ENSMUST00000133213.1
Igsf9b

immunoglobulin superfamily, member 9B

chr10_-_60003056 0.080 ENSMUST00000182912.1
ENSMUST00000020307.4
ENSMUST00000182898.1
Anapc16


anaphase promoting complex subunit 16


chr14_+_73142863 0.076 ENSMUST00000171767.1
ENSMUST00000163533.1
Rcbtb2

regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2

chr9_-_50603792 0.074 ENSMUST00000000175.4
Sdhd
succinate dehydrogenase complex, subunit D, integral membrane protein
chr2_+_181497223 0.073 ENSMUST00000108799.3
Tpd52l2
tumor protein D52-like 2
chr14_+_73142591 0.073 ENSMUST00000170368.1
Rcbtb2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr11_-_6626030 0.072 ENSMUST00000000394.7
ENSMUST00000136682.1
Tbrg4

transforming growth factor beta regulated gene 4

chr14_+_73143046 0.072 ENSMUST00000170677.1
ENSMUST00000167401.1
Rcbtb2

regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2

chr12_+_102129019 0.065 ENSMUST00000079020.4
Slc24a4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr13_-_54468805 0.065 ENSMUST00000026990.5
Thoc3
THO complex 3
chr4_+_132535542 0.065 ENSMUST00000094657.3
ENSMUST00000105940.3
ENSMUST00000105939.3
ENSMUST00000150207.1
Dnajc8



DnaJ (Hsp40) homolog, subfamily C, member 8



chr12_-_71136611 0.060 ENSMUST00000021486.8
ENSMUST00000166120.1
Timm9

translocase of inner mitochondrial membrane 9

chr6_+_70844499 0.050 ENSMUST00000034093.8
ENSMUST00000162950.1
Eif2ak3

eukaryotic translation initiation factor 2 alpha kinase 3

chr7_-_105737376 0.048 ENSMUST00000098148.4
Rrp8
ribosomal RNA processing 8, methyltransferase, homolog (yeast)
chr6_+_115544664 0.040 ENSMUST00000040234.7
Tsen2
tRNA splicing endonuclease 2 homolog (S. cerevisiae)
chr2_-_130664565 0.039 ENSMUST00000089559.4
Ddrgk1
DDRGK domain containing 1
chr11_+_58963790 0.037 ENSMUST00000075141.6
Trim17
tripartite motif-containing 17
chr14_+_73142490 0.035 ENSMUST00000170370.1
ENSMUST00000164822.1
ENSMUST00000165429.1
Rcbtb2


regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2


chr6_+_88465409 0.032 ENSMUST00000032165.9
Ruvbl1
RuvB-like protein 1
chr11_+_120467635 0.028 ENSMUST00000140862.1
ENSMUST00000106205.1
ENSMUST00000106203.1
ENSMUST00000026900.7
Hgs



HGF-regulated tyrosine kinase substrate



chr10_+_115569986 0.027 ENSMUST00000173620.1
A930009A15Rik
RIKEN cDNA A930009A15 gene
chr10_-_77166545 0.025 ENSMUST00000081654.6
Col18a1
collagen, type XVIII, alpha 1
chr2_+_76675265 0.017 ENSMUST00000111920.1
Plekha3
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 3
chr3_+_98280427 0.008 ENSMUST00000090746.2
ENSMUST00000120541.1
Hmgcs2

3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2

chr17_-_65772686 0.007 ENSMUST00000070673.7
Rab31
RAB31, member RAS oncogene family

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0031038 myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519)
0.2 1.6 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.2 0.6 GO:1904059 positive regulation of sensory perception of pain(GO:1904058) regulation of locomotor rhythm(GO:1904059)
0.2 1.5 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1 0.7 GO:0071499 response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)
0.1 0.3 GO:1904154 trimming of terminal mannose on B branch(GO:0036509) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.1 0.6 GO:1990416 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 0.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.2 GO:0048162 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.1 0.2 GO:0032829 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829)
0.1 0.2 GO:1902022 ovarian follicle rupture(GO:0001543) angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998) regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) regulation of activation of Janus kinase activity(GO:0010533) L-lysine transport(GO:1902022)
0.1 0.2 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.1 0.5 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1 0.2 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.2 GO:0046684 response to pyrethroid(GO:0046684)
0.0 0.4 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 0.4 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0097503 sialylation(GO:0097503)
0.0 0.3 GO:0033572 transferrin transport(GO:0033572)
0.0 1.1 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 1.1 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.2 GO:1902669 positive regulation of axon guidance(GO:1902669)
0.0 0.6 GO:0048599 oocyte development(GO:0048599)
0.0 0.3 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.2 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 0.4 GO:0005859 muscle myosin complex(GO:0005859)
0.1 0.4 GO:0097255 R2TP complex(GO:0097255)
0.0 0.1 GO:0097433 dense body(GO:0097433)
0.0 0.4 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.5 GO:0043203 axon hillock(GO:0043203)
0.0 0.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 0.3 GO:0004998 transferrin receptor activity(GO:0004998)
0.1 0.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.8 GO:0042923 neuropeptide binding(GO:0042923)
0.1 0.3 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 0.7 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.2 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.0 1.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0004312 fatty acid synthase activity(GO:0004312)
0.0 0.3 GO:0031402 sodium ion binding(GO:0031402)
0.0 0.0 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.6 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.2 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.3 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.3 REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.1 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.3 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation