Motif ID: Rela_Rel_Nfkb1

Z-value: 1.290

Transcription factors associated with Rela_Rel_Nfkb1:

Gene SymbolEntrez IDGene Name
Nfkb1 ENSMUSG00000028163.11 Nfkb1
Rel ENSMUSG00000020275.8 Rel
Rela ENSMUSG00000024927.7 Rela

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfkb1mm10_v2_chr3_-_135608221_1356082900.453.4e-03Click!
Relamm10_v2_chr19_+_5637475_5637486-0.221.7e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Rela_Rel_Nfkb1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_165234689 18.227 ENSMUST00000065438.6
Cdh22
cadherin 22
chr1_+_74791516 9.232 ENSMUST00000006718.8
Wnt10a
wingless related MMTV integration site 10a
chr14_-_70642268 8.000 ENSMUST00000022697.5
Fgf17
fibroblast growth factor 17
chr6_+_4755327 7.320 ENSMUST00000176551.1
Peg10
paternally expressed 10
chr8_-_61902669 7.003 ENSMUST00000121785.1
ENSMUST00000034057.7
Palld

palladin, cytoskeletal associated protein

chr18_+_4994600 5.236 ENSMUST00000140448.1
Svil
supervillin
chr7_-_25788635 4.792 ENSMUST00000002677.4
ENSMUST00000085948.4
Axl

AXL receptor tyrosine kinase

chr7_-_103843154 4.741 ENSMUST00000063957.4
Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr6_+_48841476 4.129 ENSMUST00000101426.4
Tmem176a
transmembrane protein 176A
chr6_+_48841633 4.017 ENSMUST00000168406.1
Tmem176a
transmembrane protein 176A
chr12_+_79029150 3.678 ENSMUST00000039928.5
Plekhh1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr19_-_58454580 3.570 ENSMUST00000129100.1
ENSMUST00000123957.1
Gfra1

glial cell line derived neurotrophic factor family receptor alpha 1

chr19_-_58455161 3.462 ENSMUST00000135730.1
ENSMUST00000152507.1
Gfra1

glial cell line derived neurotrophic factor family receptor alpha 1

chr17_-_35000848 3.390 ENSMUST00000166828.3
D17H6S56E-5
DNA segment, Chr 17, human D6S56E 5
chr2_-_156839790 3.335 ENSMUST00000134838.1
ENSMUST00000137463.1
ENSMUST00000149275.2
Gm14230


predicted gene 14230


chr12_+_109747903 3.215 ENSMUST00000183084.1
ENSMUST00000182300.1
Mirg

miRNA containing gene

chr5_+_92925400 3.187 ENSMUST00000172706.1
Shroom3
shroom family member 3
chr5_+_114568016 3.102 ENSMUST00000043650.7
Fam222a
family with sequence similarity 222, member A
chr19_-_58454435 3.084 ENSMUST00000169850.1
Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr12_-_91746020 3.057 ENSMUST00000166967.1
Ston2
stonin 2
chr10_-_120899067 2.959 ENSMUST00000092143.5
Msrb3
methionine sulfoxide reductase B3
chr6_+_134035691 2.951 ENSMUST00000081028.6
ENSMUST00000111963.1
Etv6

ets variant gene 6 (TEL oncogene)

chr12_-_40248073 2.931 ENSMUST00000169926.1
Ifrd1
interferon-related developmental regulator 1
chr2_-_151973387 2.917 ENSMUST00000109863.1
Fam110a
family with sequence similarity 110, member A
chr6_+_8948608 2.882 ENSMUST00000160300.1
Nxph1
neurexophilin 1
chr17_-_35000746 2.837 ENSMUST00000163360.1
D17H6S56E-5
DNA segment, Chr 17, human D6S56E 5
chr19_+_45015198 2.743 ENSMUST00000179108.1
Lzts2
leucine zipper, putative tumor suppressor 2
chr10_+_25359798 2.728 ENSMUST00000053748.8
Epb4.1l2
erythrocyte protein band 4.1-like 2
chr7_-_142899985 2.691 ENSMUST00000000219.3
Th
tyrosine hydroxylase
chr12_+_111166536 2.646 ENSMUST00000060274.6
Traf3
TNF receptor-associated factor 3
chr2_-_151973840 2.606 ENSMUST00000109865.1
ENSMUST00000109864.1
Fam110a

family with sequence similarity 110, member A

chr3_-_101836223 2.599 ENSMUST00000061831.4
Mab21l3
mab-21-like 3 (C. elegans)
chr18_+_60963517 2.528 ENSMUST00000115295.2
ENSMUST00000039904.6
Camk2a

calcium/calmodulin-dependent protein kinase II alpha

chr4_+_124986430 2.493 ENSMUST00000030687.7
Rspo1
R-spondin homolog (Xenopus laevis)
chr19_-_40271506 2.483 ENSMUST00000068439.6
Pdlim1
PDZ and LIM domain 1 (elfin)
chr6_-_24956106 2.464 ENSMUST00000127247.2
Tmem229a
transmembrane protein 229A
chr12_+_111166413 2.443 ENSMUST00000021706.4
Traf3
TNF receptor-associated factor 3
chr12_+_111166485 2.348 ENSMUST00000139162.1
Traf3
TNF receptor-associated factor 3
chr10_-_127751707 2.336 ENSMUST00000079692.5
Gpr182
G protein-coupled receptor 182
chr11_+_101316917 2.298 ENSMUST00000151385.1
Psme3
proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)
chr17_-_23745829 2.271 ENSMUST00000046525.8
Kremen2
kringle containing transmembrane protein 2
chr12_-_84194007 2.248 ENSMUST00000110294.1
Elmsan1
ELM2 and Myb/SANT-like domain containing 1
chr2_-_26294550 2.245 ENSMUST00000057224.3
4932418E24Rik
RIKEN cDNA 4932418E24 gene
chr12_+_111166349 2.229 ENSMUST00000117269.1
Traf3
TNF receptor-associated factor 3
chr1_+_109983006 2.182 ENSMUST00000145188.1
Cdh7
cadherin 7, type 2
chr5_-_106458440 2.145 ENSMUST00000086795.6
Barhl2
BarH-like 2 (Drosophila)
chr4_+_129820198 2.144 ENSMUST00000030578.7
Ptp4a2
protein tyrosine phosphatase 4a2
chr4_+_43957401 2.139 ENSMUST00000030202.7
Glipr2
GLI pathogenesis-related 2
chr6_+_34354119 2.131 ENSMUST00000038406.6
Akr1b8
aldo-keto reductase family 1, member B8
chr3_-_135691512 2.128 ENSMUST00000029812.7
Nfkb1
nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
chr7_+_75455534 2.124 ENSMUST00000147005.1
ENSMUST00000166315.1
Akap13

A kinase (PRKA) anchor protein 13

chr2_+_13573927 2.080 ENSMUST00000141365.1
ENSMUST00000028062.2
Vim

vimentin

chr3_+_40800054 2.063 ENSMUST00000168287.1
Plk4
polo-like kinase 4
chr6_+_42349826 1.997 ENSMUST00000070635.6
Zyx
zyxin
chr19_+_45015168 1.990 ENSMUST00000039016.6
Lzts2
leucine zipper, putative tumor suppressor 2
chr9_-_14614949 1.988 ENSMUST00000013220.6
ENSMUST00000160770.1
Amotl1

angiomotin-like 1

chr1_-_5019342 1.975 ENSMUST00000002533.8
Rgs20
regulator of G-protein signaling 20
chr5_+_136967859 1.964 ENSMUST00000001790.5
Cldn15
claudin 15
chr9_+_65265173 1.963 ENSMUST00000048762.1
Cilp
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr14_-_30607808 1.962 ENSMUST00000112207.1
ENSMUST00000112206.1
ENSMUST00000112202.1
ENSMUST00000112203.1
Prkcd



protein kinase C, delta



chr6_+_42350000 1.946 ENSMUST00000164375.1
Zyx
zyxin
chr10_+_111506286 1.933 ENSMUST00000164773.1
Phlda1
pleckstrin homology-like domain, family A, member 1
chr6_-_90810118 1.927 ENSMUST00000101151.3
Iqsec1
IQ motif and Sec7 domain 1
chr17_+_34039437 1.912 ENSMUST00000131134.1
ENSMUST00000087497.4
ENSMUST00000114255.1
ENSMUST00000114252.1
Col11a2



collagen, type XI, alpha 2



chr11_-_69580230 1.878 ENSMUST00000132548.1
Wrap53
WD repeat containing, antisense to Trp53
chr6_-_48840988 1.872 ENSMUST00000164733.1
Tmem176b
transmembrane protein 176B
chr3_+_40800013 1.869 ENSMUST00000026858.5
ENSMUST00000170825.1
Plk4

polo-like kinase 4

chr3_+_87971071 1.858 ENSMUST00000090973.5
Nes
nestin
chr3_+_87971129 1.854 ENSMUST00000160694.1
Nes
nestin
chr14_-_48662740 1.796 ENSMUST00000122009.1
Otx2
orthodenticle homolog 2 (Drosophila)
chr5_+_33658123 1.792 ENSMUST00000074849.6
ENSMUST00000079534.4
Tacc3

transforming, acidic coiled-coil containing protein 3

chr6_-_48841098 1.788 ENSMUST00000101429.4
Tmem176b
transmembrane protein 176B
chr9_+_64117147 1.772 ENSMUST00000034969.7
Lctl
lactase-like
chr4_-_135272798 1.770 ENSMUST00000037099.8
Clic4
chloride intracellular channel 4 (mitochondrial)
chr19_+_46304709 1.762 ENSMUST00000073116.5
Nfkb2
nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
chr17_-_28517509 1.744 ENSMUST00000114792.1
ENSMUST00000177939.1
Fkbp5

FK506 binding protein 5

chr1_+_109982710 1.739 ENSMUST00000112701.1
Cdh7
cadherin 7, type 2
chr9_-_32344237 1.730 ENSMUST00000034533.5
Kcnj5
potassium inwardly-rectifying channel, subfamily J, member 5
chr6_-_48841373 1.728 ENSMUST00000166247.1
Tmem176b
transmembrane protein 176B
chr4_-_135573623 1.717 ENSMUST00000105855.1
Grhl3
grainyhead-like 3 (Drosophila)
chr3_-_116424007 1.698 ENSMUST00000090464.4
Cdc14a
CDC14 cell division cycle 14A
chr13_+_33964659 1.688 ENSMUST00000021843.5
ENSMUST00000058978.7
Nqo2

NAD(P)H dehydrogenase, quinone 2

chr2_-_164443177 1.682 ENSMUST00000017153.3
Sdc4
syndecan 4
chrX_-_74246364 1.659 ENSMUST00000130007.1
Flna
filamin, alpha
chr13_+_51846673 1.622 ENSMUST00000021903.2
Gadd45g
growth arrest and DNA-damage-inducible 45 gamma
chr17_-_70851189 1.615 ENSMUST00000059775.8
Tgif1
TGFB-induced factor homeobox 1
chr17_-_35701937 1.609 ENSMUST00000155628.1
Ddr1
discoidin domain receptor family, member 1
chr17_-_35702040 1.592 ENSMUST00000166980.2
ENSMUST00000145900.1
Ddr1

discoidin domain receptor family, member 1

chr11_+_78301529 1.589 ENSMUST00000045026.3
Spag5
sperm associated antigen 5
chr6_+_83135812 1.583 ENSMUST00000065512.4
Rtkn
rhotekin
chr3_-_65958236 1.583 ENSMUST00000029416.7
Ccnl1
cyclin L1
chr13_+_113035111 1.576 ENSMUST00000180543.1
ENSMUST00000181568.1
ENSMUST00000109244.2
ENSMUST00000181117.1
ENSMUST00000181741.1
Cdc20b




cell division cycle 20B




chr3_+_7612702 1.569 ENSMUST00000181286.1
Gm16685
predicted gene, 16685
chr17_-_31277327 1.555 ENSMUST00000024832.7
Rsph1
radial spoke head 1 homolog (Chlamydomonas)
chr11_-_70656467 1.544 ENSMUST00000131642.1
Gm12319
predicted gene 12319
chr3_-_116423930 1.528 ENSMUST00000106491.2
Cdc14a
CDC14 cell division cycle 14A
chr14_-_37098211 1.526 ENSMUST00000022337.9
Cdhr1
cadherin-related family member 1
chr3_+_14641722 1.516 ENSMUST00000029071.8
Car13
carbonic anhydrase 13
chrX_-_74246534 1.492 ENSMUST00000101454.2
ENSMUST00000033699.6
Flna

filamin, alpha

chr3_+_89229046 1.467 ENSMUST00000041142.3
Muc1
mucin 1, transmembrane
chr11_+_117809687 1.457 ENSMUST00000120928.1
ENSMUST00000175737.1
Syngr2

synaptogyrin 2

chr5_-_137116177 1.401 ENSMUST00000054384.5
ENSMUST00000152207.1
Trim56

tripartite motif-containing 56

chr4_+_43957678 1.343 ENSMUST00000107855.1
Glipr2
GLI pathogenesis-related 2
chr9_-_72491939 1.341 ENSMUST00000185151.1
ENSMUST00000085358.5
ENSMUST00000184125.1
ENSMUST00000183574.1
ENSMUST00000184831.1
Tex9




testis expressed gene 9




chr7_-_44815658 1.313 ENSMUST00000107893.1
Atf5
activating transcription factor 5
chr11_+_98937669 1.303 ENSMUST00000107475.2
ENSMUST00000068133.3
Rara

retinoic acid receptor, alpha

chr7_-_102250086 1.302 ENSMUST00000106923.1
ENSMUST00000098230.4
Rhog

ras homolog gene family, member G

chr3_+_153973436 1.297 ENSMUST00000089948.5
Slc44a5
solute carrier family 44, member 5
chr2_-_37422869 1.294 ENSMUST00000112936.1
ENSMUST00000112934.1
Rc3h2

ring finger and CCCH-type zinc finger domains 2

chr16_-_33056174 1.293 ENSMUST00000115100.1
ENSMUST00000040309.8
Iqcg

IQ motif containing G

chr2_+_163203072 1.291 ENSMUST00000109428.2
Tox2
TOX high mobility group box family member 2
chr4_+_13743424 1.288 ENSMUST00000006761.3
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr10_-_60219260 1.285 ENSMUST00000135158.2
Chst3
carbohydrate (chondroitin 6/keratan) sulfotransferase 3
chr4_-_58499398 1.274 ENSMUST00000107570.1
Lpar1
lysophosphatidic acid receptor 1
chr5_+_90891234 1.272 ENSMUST00000031327.8
Cxcl1
chemokine (C-X-C motif) ligand 1
chr6_+_125096145 1.254 ENSMUST00000112390.1
Chd4
chromodomain helicase DNA binding protein 4
chr8_-_25201349 1.247 ENSMUST00000084512.4
ENSMUST00000084030.4
Tacc1

transforming, acidic coiled-coil containing protein 1

chr5_+_53590453 1.246 ENSMUST00000113865.1
Rbpj
recombination signal binding protein for immunoglobulin kappa J region
chr19_+_46305682 1.241 ENSMUST00000111881.2
Nfkb2
nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
chr5_+_92683625 1.237 ENSMUST00000168878.1
Shroom3
shroom family member 3
chr11_+_90030295 1.231 ENSMUST00000092788.3
Tmem100
transmembrane protein 100
chr11_+_94211431 1.229 ENSMUST00000041589.5
Tob1
transducer of ErbB-2.1
chr2_+_144556229 1.218 ENSMUST00000143573.1
ENSMUST00000028916.8
ENSMUST00000155258.1
Sec23b


SEC23B (S. cerevisiae)


chr4_-_42168603 1.214 ENSMUST00000098121.3
Gm13305
predicted gene 13305
chr14_-_103843685 1.210 ENSMUST00000172237.1
Ednrb
endothelin receptor type B
chr1_-_134079114 1.208 ENSMUST00000020692.6
Btg2
B cell translocation gene 2, anti-proliferative
chr2_+_120567687 1.200 ENSMUST00000028743.3
ENSMUST00000116437.1
ENSMUST00000153580.1
ENSMUST00000142278.1
Snap23



synaptosomal-associated protein 23



chr1_-_82291370 1.190 ENSMUST00000069799.2
Irs1
insulin receptor substrate 1
chr17_-_34862473 1.184 ENSMUST00000025229.4
ENSMUST00000176203.2
ENSMUST00000128767.1
Cfb


complement factor B


chr19_-_24861828 1.182 ENSMUST00000047666.4
Pgm5
phosphoglucomutase 5
chr7_+_45017953 1.154 ENSMUST00000044111.7
Rras
Harvey rat sarcoma oncogene, subgroup R
chr2_-_84743655 1.144 ENSMUST00000181711.1
Gm19426
predicted gene, 19426
chr9_+_91368970 1.125 ENSMUST00000172646.1
Zic4
zinc finger protein of the cerebellum 4
chr17_-_56005566 1.121 ENSMUST00000043785.6
Stap2
signal transducing adaptor family member 2
chr17_+_35821675 1.108 ENSMUST00000003635.6
Ier3
immediate early response 3
chr12_+_3954943 1.106 ENSMUST00000020990.5
Pomc
pro-opiomelanocortin-alpha
chr13_-_23698454 1.097 ENSMUST00000102967.1
Hist1h4c
histone cluster 1, H4c
chr6_+_15720654 1.094 ENSMUST00000101663.3
Mdfic
MyoD family inhibitor domain containing
chr8_+_71597648 1.091 ENSMUST00000143662.1
Fam129c
family with sequence similarity 129, member C
chr4_+_100776664 1.066 ENSMUST00000030257.8
ENSMUST00000097955.2
Cachd1

cache domain containing 1

chr7_-_29281977 1.059 ENSMUST00000098604.4
ENSMUST00000108236.3
Spint2

serine protease inhibitor, Kunitz type 2

chr2_+_105682463 1.050 ENSMUST00000140173.1
ENSMUST00000135412.1
ENSMUST00000138365.1
ENSMUST00000145744.1
Pax6



paired box gene 6



chr1_+_75450699 1.038 ENSMUST00000037708.9
Asic4
acid-sensing (proton-gated) ion channel family member 4
chr14_+_52016849 1.034 ENSMUST00000100638.2
Tmem253
transmembrane protein 253
chr14_-_62761112 1.031 ENSMUST00000053959.6
Ints6
integrator complex subunit 6
chr18_+_60803838 1.024 ENSMUST00000050487.8
ENSMUST00000097563.2
ENSMUST00000167610.1
Cd74


CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)


chr15_-_103215285 1.024 ENSMUST00000122182.1
ENSMUST00000108813.3
ENSMUST00000127191.1
Cbx5


chromobox 5


chr17_+_43667389 1.024 ENSMUST00000170988.1
Cyp39a1
cytochrome P450, family 39, subfamily a, polypeptide 1
chr2_+_120567652 1.020 ENSMUST00000110711.2
Snap23
synaptosomal-associated protein 23
chr10_+_128790903 1.017 ENSMUST00000026411.6
Mmp19
matrix metallopeptidase 19
chr10_-_49788743 1.012 ENSMUST00000105483.1
ENSMUST00000105487.1
Grik2

glutamate receptor, ionotropic, kainate 2 (beta 2)

chr5_+_53590215 1.011 ENSMUST00000037618.6
Rbpj
recombination signal binding protein for immunoglobulin kappa J region
chr12_+_104214538 1.008 ENSMUST00000121337.1
ENSMUST00000167049.1
ENSMUST00000101080.1
Serpina3f


serine (or cysteine) peptidase inhibitor, clade A, member 3F


chr9_-_22389113 1.008 ENSMUST00000040912.7
Anln
anillin, actin binding protein
chr3_+_90080442 1.006 ENSMUST00000127955.1
Tpm3
tropomyosin 3, gamma
chr8_-_122432924 1.002 ENSMUST00000017604.8
Cyba
cytochrome b-245, alpha polypeptide
chrX_-_75130844 0.991 ENSMUST00000114092.1
ENSMUST00000132501.1
ENSMUST00000153318.1
ENSMUST00000155742.1
Mpp1



membrane protein, palmitoylated



chr10_-_53638269 0.990 ENSMUST00000164393.1
Fam184a
family with sequence similarity 184, member A
chr7_+_79500081 0.989 ENSMUST00000181511.2
ENSMUST00000182937.1
AI854517

expressed sequence AI854517

chr5_+_9100681 0.989 ENSMUST00000115365.1
Tmem243
transmembrane protein 243, mitochondrial
chr8_+_70863127 0.974 ENSMUST00000050921.2
A230052G05Rik
RIKEN cDNA A230052G05 gene
chr12_-_10900296 0.970 ENSMUST00000085735.2
Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chr5_+_96373955 0.969 ENSMUST00000036019.4
Fras1
Fraser syndrome 1 homolog (human)
chr13_-_49309217 0.967 ENSMUST00000110087.2
Fgd3
FYVE, RhoGEF and PH domain containing 3
chr4_+_128755364 0.963 ENSMUST00000106077.1
A3galt2
alpha 1,3-galactosyltransferase 2 (isoglobotriaosylceramide synthase)
chr17_+_37193889 0.963 ENSMUST00000038844.6
Ubd
ubiquitin D
chr7_-_127020321 0.960 ENSMUST00000032918.2
Pagr1a
PAXIP1 associated glutamate rich protein 1A
chr19_+_8871512 0.951 ENSMUST00000166407.1
Ubxn1
UBX domain protein 1
chr18_-_33213766 0.943 ENSMUST00000119991.1
ENSMUST00000118990.1
Stard4

StAR-related lipid transfer (START) domain containing 4

chr10_+_93160824 0.934 ENSMUST00000069965.7
Cdk17
cyclin-dependent kinase 17
chr8_+_84946987 0.918 ENSMUST00000067472.7
ENSMUST00000109740.2
Rtbdn

retbindin

chr10_+_4611971 0.916 ENSMUST00000105590.1
ENSMUST00000067086.7
Esr1

estrogen receptor 1 (alpha)

chr11_+_101176041 0.916 ENSMUST00000103109.3
Cntnap1
contactin associated protein-like 1
chr1_+_172499948 0.906 ENSMUST00000111230.1
Tagln2
transgelin 2
chr12_-_80260356 0.905 ENSMUST00000021554.8
Actn1
actinin, alpha 1
chr10_+_94550852 0.897 ENSMUST00000148910.1
ENSMUST00000117460.1
Tmcc3

transmembrane and coiled coil domains 3

chr14_-_30626196 0.896 ENSMUST00000112210.3
ENSMUST00000112211.2
ENSMUST00000112208.1
Prkcd


protein kinase C, delta


chr2_+_103073669 0.895 ENSMUST00000011055.6
Apip
APAF1 interacting protein
chr13_-_21783391 0.884 ENSMUST00000099704.3
Hist1h3i
histone cluster 1, H3i
chr15_+_99126513 0.876 ENSMUST00000063517.4
Spats2
spermatogenesis associated, serine-rich 2
chr19_+_8871636 0.876 ENSMUST00000096255.5
Ubxn1
UBX domain protein 1
chr4_-_135971894 0.861 ENSMUST00000105852.1
Lypla2
lysophospholipase 2
chr4_-_95052170 0.860 ENSMUST00000058555.2
Jun
Jun oncogene
chr5_-_30105359 0.858 ENSMUST00000127749.3
3110082J24Rik
RIKEN cDNA 3110082J24 gene
chr11_-_106159902 0.858 ENSMUST00000064545.4
Limd2
LIM domain containing 2
chr7_-_109616548 0.845 ENSMUST00000077909.1
ENSMUST00000084738.3
St5

suppression of tumorigenicity 5

chr8_+_106683052 0.835 ENSMUST00000048359.4
Tango6
transport and golgi organization 6
chr4_-_95052188 0.834 ENSMUST00000107094.1
Jun
Jun oncogene
chr2_+_69861562 0.825 ENSMUST00000090852.4
ENSMUST00000166411.1
Ssb

Sjogren syndrome antigen B

chr5_+_30105161 0.824 ENSMUST00000058045.4
Gareml
GRB2 associated, regulator of MAPK1-like
chr10_-_77089428 0.816 ENSMUST00000156009.1
Col18a1
collagen, type XVIII, alpha 1
chr13_+_44730726 0.815 ENSMUST00000173704.1
ENSMUST00000044608.7
ENSMUST00000173367.1
Jarid2


jumonji, AT rich interactive domain 2


chr11_-_100759740 0.812 ENSMUST00000107361.2
Kcnh4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr6_-_24664960 0.802 ENSMUST00000041737.7
ENSMUST00000031695.8
Wasl

Wiskott-Aldrich syndrome-like (human)

chr5_-_148552783 0.801 ENSMUST00000079324.7
ENSMUST00000164904.1
Ubl3

ubiquitin-like 3

chr2_+_156840077 0.799 ENSMUST00000081335.6
ENSMUST00000073352.3
Tgif2

TGFB-induced factor homeobox 2

chr11_-_78697370 0.789 ENSMUST00000142739.1
Nlk
nemo like kinase
chr3_+_90248172 0.788 ENSMUST00000015467.8
Slc39a1
solute carrier family 39 (zinc transporter), member 1
chr10_+_7725997 0.783 ENSMUST00000019929.6
ENSMUST00000165806.1
Katna1

katanin p60 (ATPase-containing) subunit A1

chr17_+_32685655 0.781 ENSMUST00000008801.6
Cyp4f15
cytochrome P450, family 4, subfamily f, polypeptide 15

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 13.7 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
1.6 4.8 GO:0097350 neutrophil clearance(GO:0097350)
1.1 3.2 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
1.0 9.7 GO:0008063 Toll signaling pathway(GO:0008063)
0.9 4.7 GO:0015671 oxygen transport(GO:0015671)
0.9 1.7 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.8 11.5 GO:0048733 sebaceous gland development(GO:0048733)
0.7 3.0 GO:0030091 protein repair(GO:0030091)
0.7 16.8 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.7 2.2 GO:0016115 terpenoid catabolic process(GO:0016115)
0.7 2.7 GO:0042414 epinephrine metabolic process(GO:0042414)
0.7 2.6 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.6 1.9 GO:0060023 soft palate development(GO:0060023)
0.6 4.2 GO:0098535 de novo centriole assembly(GO:0098535)
0.6 2.9 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.5 2.1 GO:1903416 negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137) regulation of calcidiol 1-monooxygenase activity(GO:0060558) response to glycoside(GO:1903416)
0.5 1.0 GO:0033864 positive regulation of NAD(P)H oxidase activity(GO:0033864)
0.5 1.4 GO:0015938 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) acetyl-CoA catabolic process(GO:0046356)
0.5 7.6 GO:0003334 keratinocyte development(GO:0003334)
0.4 1.3 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.4 1.8 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.4 3.1 GO:0007296 vitellogenesis(GO:0007296)
0.4 1.3 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.4 2.1 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.4 1.2 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.4 1.6 GO:0070859 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.4 1.6 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.4 2.7 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.4 1.9 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.4 2.2 GO:0070094 positive regulation of glucagon secretion(GO:0070094)
0.4 2.2 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.4 1.1 GO:0035934 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.4 1.8 GO:2000157 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.4 1.4 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.3 1.7 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
0.3 1.7 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.3 1.0 GO:1904170 regulation of bleb assembly(GO:1904170)
0.3 4.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.3 3.2 GO:0000022 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.3 1.3 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.3 1.3 GO:1900150 regulation of defense response to fungus(GO:1900150)
0.3 1.2 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.3 0.3 GO:0033860 regulation of NAD(P)H oxidase activity(GO:0033860)
0.2 0.7 GO:0006657 CDP-choline pathway(GO:0006657)
0.2 0.5 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.2 0.7 GO:0051105 regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.2 2.1 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.2 0.9 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.2 0.9 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.2 0.7 GO:0032916 positive regulation of transforming growth factor beta3 production(GO:0032916)
0.2 0.7 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.2 0.9 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509) pyroptosis(GO:0070269)
0.2 0.7 GO:0090403 regulation of purine nucleotide catabolic process(GO:0033121) negative regulation of purine nucleotide catabolic process(GO:0033122) oxidative stress-induced premature senescence(GO:0090403)
0.2 3.0 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.2 2.6 GO:2000254 regulation of male germ cell proliferation(GO:2000254)
0.2 2.5 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.2 1.3 GO:0072553 terminal button organization(GO:0072553)
0.2 1.2 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.2 1.0 GO:0002901 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.2 1.8 GO:0042095 interferon-gamma biosynthetic process(GO:0042095)
0.2 1.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 0.6 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.2 0.7 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.2 1.8 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.2 0.5 GO:0090135 actin filament branching(GO:0090135) negative regulation of phospholipase C activity(GO:1900275)
0.2 0.9 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.2 0.7 GO:0070307 lens fiber cell development(GO:0070307)
0.2 0.5 GO:0035622 intrahepatic bile duct development(GO:0035622) cholangiocyte proliferation(GO:1990705)
0.2 1.3 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.2 1.1 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.2 0.6 GO:0006545 glycine biosynthetic process(GO:0006545)
0.2 1.7 GO:0061436 establishment of skin barrier(GO:0061436)
0.2 2.4 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.2 0.6 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.2 2.6 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.6 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.1 0.9 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 1.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.5 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.1 1.6 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.1 0.8 GO:0051013 microtubule severing(GO:0051013)
0.1 1.4 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 1.3 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.1 2.4 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 0.4 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.1 0.6 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.2 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.1 0.5 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.1 0.4 GO:0040009 regulation of growth rate(GO:0040009)
0.1 1.3 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.1 2.7 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.1 1.0 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304) histone H3-K27 demethylation(GO:0071557)
0.1 0.6 GO:1900153 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.1 0.3 GO:2000659 regulation of circadian sleep/wake cycle, non-REM sleep(GO:0045188) regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.1 0.3 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.3 GO:0072592 oxygen metabolic process(GO:0072592)
0.1 0.9 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.1 1.0 GO:0030259 lipid glycosylation(GO:0030259)
0.1 7.0 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.1 0.4 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.1 1.0 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 4.1 GO:0048536 spleen development(GO:0048536)
0.1 0.5 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.1 0.8 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 1.0 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 0.2 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.1 0.6 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.1 0.7 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.1 0.3 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.2 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678)
0.1 4.0 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.1 0.4 GO:0032382 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373)
0.1 0.4 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 1.2 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 0.3 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.1 1.3 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.1 0.3 GO:0060056 mammary gland involution(GO:0060056)
0.1 1.0 GO:0070842 aggresome assembly(GO:0070842)
0.1 1.4 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.1 0.2 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
0.1 2.1 GO:0001709 cell fate determination(GO:0001709)
0.1 0.2 GO:2000334 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 1.4 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.1 0.4 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 1.9 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 4.0 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.1 5.2 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.1 0.3 GO:0006547 histidine metabolic process(GO:0006547)
0.1 1.3 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.1 1.2 GO:0036344 platelet morphogenesis(GO:0036344)
0.1 0.6 GO:0032494 response to peptidoglycan(GO:0032494)
0.1 1.1 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.1 0.4 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 0.5 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.1 0.8 GO:0045830 positive regulation of isotype switching(GO:0045830)
0.1 0.3 GO:1990839 response to endothelin(GO:1990839)
0.1 0.5 GO:0048102 autophagic cell death(GO:0048102)
0.1 0.5 GO:0061032 visceral serous pericardium development(GO:0061032)
0.1 0.8 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1 0.2 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 1.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.4 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.1 0.2 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.1 1.8 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.4 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.1 0.4 GO:1904816 positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.1 0.2 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.1 0.2 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.2 GO:0006481 C-terminal protein methylation(GO:0006481)
0.1 0.3 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 0.1 GO:0045988 negative regulation of striated muscle contraction(GO:0045988)
0.1 0.1 GO:1904245 regulation of polynucleotide adenylyltransferase activity(GO:1904245)
0.1 0.1 GO:2001184 regulation of interleukin-12 secretion(GO:2001182) positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.8 GO:0019884 antigen processing and presentation of exogenous antigen(GO:0019884)
0.0 1.0 GO:0016180 snRNA processing(GO:0016180)
0.0 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 1.7 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.3 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.3 GO:0040031 snRNA modification(GO:0040031)
0.0 0.2 GO:0032621 interleukin-18 production(GO:0032621)
0.0 1.5 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 1.2 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.8 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.5 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.2 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.2 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.0 0.3 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.0 0.2 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.2 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 1.4 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.2 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 1.2 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.2 GO:0071774 response to fibroblast growth factor(GO:0071774)
0.0 0.1 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.2 GO:0007603 phototransduction, visible light(GO:0007603)
0.0 0.1 GO:1901731 calcium-mediated signaling using extracellular calcium source(GO:0035585) positive regulation of platelet aggregation(GO:1901731)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.5 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0035963 response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.0 2.9 GO:2000045 regulation of G1/S transition of mitotic cell cycle(GO:2000045)
0.0 0.4 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0 0.3 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.3 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.1 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.0 1.9 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.0 0.5 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 4.5 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 1.7 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.1 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 2.3 GO:0048736 appendage development(GO:0048736) limb development(GO:0060173)
0.0 0.2 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.7 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.4 GO:0001706 endoderm formation(GO:0001706)
0.0 0.4 GO:0001967 suckling behavior(GO:0001967)
0.0 0.2 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.1 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.0 0.6 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.5 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.1 GO:0031441 negative regulation of mRNA 3'-end processing(GO:0031441)
0.0 0.1 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.5 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.1 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.0 0.9 GO:0060021 palate development(GO:0060021)
0.0 0.2 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.5 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.4 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 0.3 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.0 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.8 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.0 GO:0001828 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.0 0.3 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.1 GO:0039702 viral budding via host ESCRT complex(GO:0039702)
0.0 0.3 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.0 GO:1904749 regulation of protein localization to nucleolus(GO:1904749) positive regulation of protein localization to nucleolus(GO:1904751)
0.0 0.4 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 0.6 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.5 GO:0002181 cytoplasmic translation(GO:0002181)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.8 2.5 GO:0099573 glutamatergic postsynaptic density(GO:0099573)
0.7 3.9 GO:0098536 deuterosome(GO:0098536)
0.6 3.2 GO:0031523 Myb complex(GO:0031523)
0.6 4.7 GO:0005833 hemoglobin complex(GO:0005833)
0.6 8.7 GO:0035631 CD40 receptor complex(GO:0035631)
0.6 2.3 GO:0008537 proteasome activator complex(GO:0008537)
0.5 2.1 GO:0045098 type III intermediate filament(GO:0045098)
0.5 3.5 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.5 2.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.4 1.2 GO:0005899 insulin receptor complex(GO:0005899)
0.3 1.7 GO:0035976 AP1 complex(GO:0035976)
0.3 1.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.2 1.4 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.2 0.9 GO:0032127 dense core granule membrane(GO:0032127)
0.2 2.3 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.2 1.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 1.0 GO:0005826 actomyosin contractile ring(GO:0005826)
0.2 1.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 1.6 GO:0001520 outer dense fiber(GO:0001520)
0.2 0.8 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.2 7.2 GO:0002102 podosome(GO:0002102)
0.2 1.5 GO:0030863 cortical cytoskeleton(GO:0030863)
0.2 7.5 GO:0043034 costamere(GO:0043034)
0.2 0.6 GO:0070552 BRISC complex(GO:0070552)
0.2 1.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 1.0 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 3.4 GO:0043657 host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657)
0.1 1.8 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 0.5 GO:0043293 apoptosome(GO:0043293)
0.1 0.9 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 0.9 GO:0033270 paranode region of axon(GO:0033270)
0.1 1.2 GO:0002177 manchette(GO:0002177)
0.1 1.9 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.3 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.6 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.7 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.1 0.8 GO:0030478 actin cap(GO:0030478)
0.1 0.6 GO:0044305 calyx of Held(GO:0044305)
0.1 1.2 GO:0030057 desmosome(GO:0030057)
0.1 0.4 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.3 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.1 5.0 GO:0005882 intermediate filament(GO:0005882)
0.1 1.1 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 0.6 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.3 GO:0070876 SOSS complex(GO:0070876)
0.1 0.7 GO:0042587 glycogen granule(GO:0042587)
0.1 1.5 GO:0010369 chromocenter(GO:0010369)
0.1 1.6 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 10.3 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.2 GO:0032039 integrator complex(GO:0032039)
0.1 0.4 GO:0032389 MutLalpha complex(GO:0032389)
0.1 1.2 GO:0032156 septin cytoskeleton(GO:0032156)
0.1 1.9 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 0.2 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.1 0.2 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 0.2 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 0.5 GO:0071664 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.1 0.2 GO:0035339 SPOTS complex(GO:0035339)
0.1 1.9 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 1.1 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 0.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 0.5 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 2.4 GO:0008180 COP9 signalosome(GO:0008180)
0.1 5.0 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 0.3 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.4 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 1.1 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.5 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 4.7 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.3 GO:0009986 cell surface(GO:0009986)
0.0 0.3 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.8 GO:0071564 npBAF complex(GO:0071564)
0.0 0.6 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.5 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 4.8 GO:0043296 apical junction complex(GO:0043296)
0.0 0.3 GO:0097422 tubular endosome(GO:0097422)
0.0 4.0 GO:0000922 spindle pole(GO:0000922)
0.0 0.7 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 2.6 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.1 GO:0042827 platelet dense granule(GO:0042827)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 1.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.1 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.5 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 2.4 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.6 GO:0030914 STAGA complex(GO:0030914)
0.0 2.8 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 1.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.6 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.1 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.7 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 1.2 GO:0005911 cell-cell junction(GO:0005911)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.4 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.5 GO:0000792 heterochromatin(GO:0000792)
0.0 0.2 GO:0000346 transcription export complex(GO:0000346)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 1.2 GO:0030139 endocytic vesicle(GO:0030139)
0.0 1.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.8 GO:0005643 nuclear pore(GO:0005643)
0.0 0.1 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.3 GO:0015030 Cajal body(GO:0015030)
0.0 3.8 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 2.5 GO:0043235 receptor complex(GO:0043235)
0.0 0.4 GO:0016235 aggresome(GO:0016235)
0.0 1.0 GO:0030496 midbody(GO:0030496)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.0 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
1.2 4.7 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.8 9.7 GO:0031996 thioesterase binding(GO:0031996)
0.8 3.2 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.7 2.9 GO:0070976 calcium-independent protein kinase C activity(GO:0004699) TIR domain binding(GO:0070976)
0.6 2.6 GO:1990254 keratin filament binding(GO:1990254)
0.5 2.7 GO:0035240 dopamine binding(GO:0035240)
0.5 3.0 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.5 1.4 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.5 1.8 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.4 1.8 GO:0008422 beta-glucosidase activity(GO:0008422)
0.4 4.0 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.4 4.8 GO:0032036 myosin heavy chain binding(GO:0032036)
0.4 2.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.4 1.2 GO:0004962 endothelin receptor activity(GO:0004962)
0.4 1.9 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.4 1.1 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.3 1.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.3 3.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.3 3.7 GO:0019215 intermediate filament binding(GO:0019215)
0.3 1.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.3 1.3 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.3 0.9 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.3 2.3 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.3 1.7 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.2 0.7 GO:0034437 glycoprotein transporter activity(GO:0034437)
0.2 1.4 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.2 9.4 GO:0005109 frizzled binding(GO:0005109)
0.2 0.7 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.2 2.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 2.5 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.2 0.6 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.2 1.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 0.4 GO:0046977 TAP binding(GO:0046977) TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.2 0.6 GO:0001565 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
0.2 2.0 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2 1.6 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.2 0.8 GO:0050436 microfibril binding(GO:0050436)
0.2 1.3 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.2 1.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.2 1.0 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.2 0.6 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.7 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.4 GO:0097677 STAT family protein binding(GO:0097677)
0.1 0.7 GO:0004849 uridine kinase activity(GO:0004849)
0.1 1.6 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.5 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 2.9 GO:0070410 co-SMAD binding(GO:0070410)
0.1 2.2 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.8 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 1.0 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 1.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.7 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.1 1.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.8 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.3 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 0.6 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.8 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 1.9 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 11.7 GO:0005178 integrin binding(GO:0005178)
0.1 2.0 GO:0017127 cholesterol transporter activity(GO:0017127)
0.1 1.3 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.4 GO:0004111 creatine kinase activity(GO:0004111)
0.1 1.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.3 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.1 4.1 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 1.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 2.4 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.6 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 2.2 GO:0042805 actinin binding(GO:0042805)
0.1 1.7 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.3 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.1 0.2 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.1 1.5 GO:0004707 MAP kinase activity(GO:0004707)
0.1 0.3 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.1 0.4 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.4 GO:0000405 bubble DNA binding(GO:0000405)
0.1 0.7 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.1 0.3 GO:0035877 death effector domain binding(GO:0035877)
0.1 1.1 GO:0030957 Tat protein binding(GO:0030957)
0.1 0.2 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 0.2 GO:0030984 kininogen binding(GO:0030984)
0.1 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.9 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 1.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 2.8 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 0.5 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 10.6 GO:0051015 actin filament binding(GO:0051015)
0.1 0.2 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.1 1.0 GO:0070628 proteasome binding(GO:0070628)
0.1 0.2 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.1 1.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.5 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.5 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.4 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.3 GO:0034452 dynactin binding(GO:0034452)
0.0 0.7 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.1 GO:0098518 polynucleotide 3'-phosphatase activity(GO:0046403) polynucleotide phosphatase activity(GO:0098518)
0.0 1.3 GO:0005272 sodium channel activity(GO:0005272)
0.0 4.3 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.5 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.5 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.4 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.5 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.4 GO:0052744 phosphatidylinositol-3-phosphatase activity(GO:0004438) phosphatidylinositol monophosphate phosphatase activity(GO:0052744)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.3 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 1.5 GO:0020037 heme binding(GO:0020037)
0.0 2.5 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 1.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.2 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 1.0 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.2 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.9 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.8 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 11.7 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.4 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.9 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.3 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 0.2 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.9 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.5 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.5 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 1.4 GO:0035326 enhancer binding(GO:0035326)
0.0 0.2 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.6 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.2 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 1.0 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.2 GO:0050733 RS domain binding(GO:0050733)
0.0 0.7 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.8 GO:0019003 GDP binding(GO:0019003)
0.0 0.2 GO:0030553 cGMP binding(GO:0030553)
0.0 0.7 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 0.1 GO:0001222 transcription corepressor binding(GO:0001222) protein tag(GO:0031386)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 10.4 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.2 14.1 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.2 3.9 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.2 5.6 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.2 9.2 PID_FGF_PATHWAY FGF signaling pathway
0.2 3.5 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.2 4.8 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.2 1.0 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.2 1.1 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.2 4.9 ST_G_ALPHA_I_PATHWAY G alpha i Pathway
0.1 0.9 PID_IL23_PATHWAY IL23-mediated signaling events
0.1 3.9 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.1 2.3 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.1 5.2 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 4.9 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.1 2.7 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.1 4.4 PID_AURORA_B_PATHWAY Aurora B signaling
0.1 6.9 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.1 0.1 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.1 9.3 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.1 7.2 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.1 2.2 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.1 1.6 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.1 0.5 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.1 2.8 PID_IL12_2PATHWAY IL12-mediated signaling events
0.1 1.6 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 2.1 PID_INTEGRIN1_PATHWAY Beta1 integrin cell surface interactions
0.0 0.2 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.4 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 1.1 PID_CDC42_PATHWAY CDC42 signaling events
0.0 1.1 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 1.4 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.0 0.9 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.7 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 0.5 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.4 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.0 0.3 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.8 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.5 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 0.3 PID_BARD1_PATHWAY BARD1 signaling events
0.0 1.3 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 8.0 REACTOME_SIGNALING_BY_FGFR3_MUTANTS Genes involved in Signaling by FGFR3 mutants
0.7 9.8 REACTOME_ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.3 2.1 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.2 2.7 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.2 1.2 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.2 9.7 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.2 3.3 REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.2 2.8 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 4.8 REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS Genes involved in G alpha (z) signalling events
0.1 1.6 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.1 1.7 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 3.2 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 3.1 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.1 9.0 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 1.4 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 1.6 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 1.6 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 3.1 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 2.7 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.1 1.7 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.1 1.1 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 1.6 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.1 0.3 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 1.3 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 1.9 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.1 1.0 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 2.0 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.1 4.4 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 0.7 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 0.7 REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.1 0.9 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.1 0.9 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.8 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.2 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 0.3 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.5 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.1 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 1.9 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.5 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 1.0 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.4 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.7 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.6 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.0 0.6 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 1.9 REACTOME_G_ALPHA1213_SIGNALLING_EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.2 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.0 1.3 REACTOME_AUTODEGRADATION_OF_CDH1_BY_CDH1_APC_C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0 0.9 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.5 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.6 REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.5 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 2.5 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 2.2 REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS Genes involved in G alpha (q) signalling events
0.0 0.6 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.6 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.0 0.7 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.4 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein