Motif ID: Nr2c1
Z-value: 0.550

Transcription factors associated with Nr2c1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Nr2c1 | ENSMUSG00000005897.8 | Nr2c1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Nr2c1 | mm10_v2_chr10_+_94147982_94148023 | -0.24 | 1.3e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 1.7 | GO:1900149 | positive regulation of Schwann cell migration(GO:1900149) |
0.4 | 1.3 | GO:0071929 | alpha-tubulin acetylation(GO:0071929) |
0.4 | 2.3 | GO:0030643 | cellular phosphate ion homeostasis(GO:0030643) phosphate ion transmembrane transport(GO:0035435) cellular trivalent inorganic anion homeostasis(GO:0072502) |
0.3 | 0.8 | GO:0070973 | COPI-coated vesicle budding(GO:0035964) protein localization to endoplasmic reticulum exit site(GO:0070973) |
0.2 | 0.5 | GO:1900147 | Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147) |
0.2 | 1.1 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
0.2 | 0.6 | GO:0035359 | negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) |
0.2 | 3.3 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
0.1 | 0.9 | GO:0014874 | response to stimulus involved in regulation of muscle adaptation(GO:0014874) |
0.1 | 1.2 | GO:0098937 | dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) |
0.1 | 1.0 | GO:0042760 | very long-chain fatty acid catabolic process(GO:0042760) |
0.1 | 0.6 | GO:0043314 | negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313) |
0.1 | 0.3 | GO:0045204 | MAPK export from nucleus(GO:0045204) |
0.1 | 0.7 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
0.1 | 0.3 | GO:0033615 | mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615) |
0.1 | 0.7 | GO:0032264 | IMP salvage(GO:0032264) |
0.1 | 1.1 | GO:1903818 | positive regulation of voltage-gated potassium channel activity(GO:1903818) |
0.1 | 2.5 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
0.1 | 0.3 | GO:0032275 | luteinizing hormone secretion(GO:0032275) positive regulation of gonadotropin secretion(GO:0032278) |
0.1 | 0.5 | GO:0098909 | establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909) |
0.1 | 1.4 | GO:0036295 | cellular response to increased oxygen levels(GO:0036295) |
0.1 | 1.4 | GO:0030033 | microvillus assembly(GO:0030033) |
0.0 | 0.3 | GO:0015879 | carnitine transport(GO:0015879) |
0.0 | 0.9 | GO:0001553 | luteinization(GO:0001553) |
0.0 | 0.9 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
0.0 | 0.6 | GO:0051574 | positive regulation of histone H3-K9 methylation(GO:0051574) |
0.0 | 0.4 | GO:0034551 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033) |
0.0 | 0.3 | GO:0060903 | positive regulation of meiosis I(GO:0060903) |
0.0 | 0.3 | GO:0003056 | regulation of vascular smooth muscle contraction(GO:0003056) |
0.0 | 0.2 | GO:0016557 | peroxisome membrane biogenesis(GO:0016557) |
0.0 | 1.7 | GO:0034605 | cellular response to heat(GO:0034605) |
0.0 | 0.1 | GO:0015793 | glycerol transport(GO:0015793) |
0.0 | 0.4 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
0.0 | 0.2 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
0.0 | 0.4 | GO:0031069 | hair follicle morphogenesis(GO:0031069) |
0.0 | 0.6 | GO:2001240 | negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240) |
0.0 | 0.5 | GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289) |
0.0 | 0.2 | GO:0071044 | histone mRNA catabolic process(GO:0071044) |
0.0 | 2.6 | GO:0010977 | negative regulation of neuron projection development(GO:0010977) |
0.0 | 2.0 | GO:0099643 | neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643) |
0.0 | 2.0 | GO:0002244 | hematopoietic progenitor cell differentiation(GO:0002244) |
0.0 | 0.4 | GO:1900078 | positive regulation of cellular response to insulin stimulus(GO:1900078) |
0.0 | 0.1 | GO:0031665 | negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665) |
0.0 | 0.6 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
0.0 | 0.0 | GO:0015938 | coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 1.7 | GO:0072534 | perineuronal net(GO:0072534) |
0.5 | 2.5 | GO:0038039 | G-protein coupled receptor heterodimeric complex(GO:0038039) |
0.2 | 1.4 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
0.1 | 1.3 | GO:0097427 | microtubule bundle(GO:0097427) |
0.1 | 2.5 | GO:0071565 | nBAF complex(GO:0071565) |
0.1 | 5.6 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
0.1 | 1.7 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
0.0 | 1.1 | GO:0030673 | axolemma(GO:0030673) |
0.0 | 2.9 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.0 | 1.8 | GO:0016459 | myosin complex(GO:0016459) |
0.0 | 0.6 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
0.0 | 0.8 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
0.0 | 0.3 | GO:0031528 | microvillus membrane(GO:0031528) |
0.0 | 0.3 | GO:0032279 | asymmetric synapse(GO:0032279) |
0.0 | 0.8 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
0.0 | 0.2 | GO:0035631 | CD40 receptor complex(GO:0035631) |
0.0 | 0.6 | GO:0016235 | aggresome(GO:0016235) |
0.0 | 0.9 | GO:0016529 | sarcoplasmic reticulum(GO:0016529) |
0.0 | 0.6 | GO:1990391 | DNA repair complex(GO:1990391) |
0.0 | 0.7 | GO:0005882 | intermediate filament(GO:0005882) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 2.3 | GO:0000822 | inositol hexakisphosphate binding(GO:0000822) |
0.4 | 2.5 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
0.4 | 1.1 | GO:0070139 | ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139) |
0.3 | 1.5 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
0.2 | 1.3 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
0.2 | 0.7 | GO:0004103 | choline kinase activity(GO:0004103) |
0.1 | 0.3 | GO:0005124 | scavenger receptor binding(GO:0005124) |
0.1 | 0.7 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
0.1 | 1.2 | GO:0050811 | GABA receptor binding(GO:0050811) |
0.1 | 1.4 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
0.1 | 0.4 | GO:0047184 | 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) |
0.1 | 1.1 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
0.1 | 1.0 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
0.1 | 1.7 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
0.1 | 0.5 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
0.0 | 0.2 | GO:0004095 | carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416) |
0.0 | 0.9 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
0.0 | 0.4 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
0.0 | 0.1 | GO:0015254 | glycerol channel activity(GO:0015254) |
0.0 | 0.8 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
0.0 | 0.5 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
0.0 | 0.2 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
0.0 | 0.3 | GO:0042166 | acetylcholine binding(GO:0042166) |
0.0 | 0.6 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
0.0 | 0.3 | GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
0.0 | 0.3 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
0.0 | 0.6 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
0.0 | 0.3 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
0.0 | 0.3 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
0.0 | 1.8 | GO:0003774 | motor activity(GO:0003774) |
0.0 | 0.6 | GO:0032452 | histone demethylase activity(GO:0032452) |
0.0 | 0.5 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.9 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
0.0 | 0.9 | PID_P38_MKK3_6PATHWAY | p38 MAPK signaling pathway |
0.0 | 0.8 | PID_ARF_3PATHWAY | Arf1 pathway |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 2.5 | REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
0.2 | 2.3 | REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Dopamine Neurotransmitter Release Cycle |
0.1 | 0.8 | REACTOME_COPI_MEDIATED_TRANSPORT | Genes involved in COPI Mediated Transport |
0.1 | 1.4 | REACTOME_INSULIN_RECEPTOR_RECYCLING | Genes involved in Insulin receptor recycling |
0.1 | 0.7 | REACTOME_SYNTHESIS_OF_PE | Genes involved in Synthesis of PE |
0.0 | 0.4 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PS | Genes involved in Acyl chain remodelling of PS |
0.0 | 0.7 | REACTOME_PURINE_SALVAGE | Genes involved in Purine salvage |
0.0 | 0.3 | REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
0.0 | 0.8 | REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle |
0.0 | 0.5 | REACTOME_ACTIVATION_OF_RAC | Genes involved in Activation of Rac |
0.0 | 1.1 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
0.0 | 0.1 | REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
0.0 | 0.5 | REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |