Motif ID: Pax7

Z-value: 0.417


Transcription factors associated with Pax7:

Gene SymbolEntrez IDGene Name
Pax7 ENSMUSG00000028736.7 Pax7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pax7mm10_v2_chr4_-_139833524_1398335350.076.8e-01Click!


Activity profile for motif Pax7.

activity profile for motif Pax7


Sorted Z-values histogram for motif Pax7

Sorted Z-values for motif Pax7



Network of associatons between targets according to the STRING database.



First level regulatory network of Pax7

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_67113909 3.123 ENSMUST00000092640.5
St3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr12_+_117843489 1.954 ENSMUST00000021592.9
Cdca7l
cell division cycle associated 7 like
chr10_+_85386813 1.448 ENSMUST00000105307.1
ENSMUST00000020231.3
Btbd11

BTB (POZ) domain containing 11

chr4_-_14621805 1.150 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr19_-_15924560 1.010 ENSMUST00000162053.1
Psat1
phosphoserine aminotransferase 1
chr19_-_15924928 0.958 ENSMUST00000025542.3
Psat1
phosphoserine aminotransferase 1
chr15_-_37459327 0.844 ENSMUST00000119730.1
ENSMUST00000120746.1
Ncald

neurocalcin delta

chr15_-_64922290 0.783 ENSMUST00000023007.5
Adcy8
adenylate cyclase 8
chr4_+_102589687 0.780 ENSMUST00000097949.4
ENSMUST00000106901.1
Pde4b

phosphodiesterase 4B, cAMP specific

chr5_-_138170992 0.689 ENSMUST00000139983.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr4_-_14621669 0.578 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr4_-_14621494 0.522 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chr9_-_20959785 0.471 ENSMUST00000177754.1
Dnmt1
DNA methyltransferase (cytosine-5) 1
chr5_+_26817357 0.386 ENSMUST00000071500.6
Dpp6
dipeptidylpeptidase 6
chr13_+_23533869 0.375 ENSMUST00000073261.2
Hist1h2af
histone cluster 1, H2af
chr2_-_33718789 0.357 ENSMUST00000130532.1
9430024E24Rik
RIKEN cDNA 9430024E24 gene
chr10_-_62379852 0.327 ENSMUST00000143236.1
ENSMUST00000133429.1
ENSMUST00000132926.1
ENSMUST00000116238.2
Hk1



hexokinase 1



chr13_-_102906046 0.302 ENSMUST00000171791.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr17_-_35516780 0.295 ENSMUST00000160885.1
ENSMUST00000159009.1
ENSMUST00000161012.1
Tcf19


transcription factor 19


chr8_-_61902669 0.293 ENSMUST00000121785.1
ENSMUST00000034057.7
Palld

palladin, cytoskeletal associated protein

chr9_-_71163224 0.292 ENSMUST00000074465.2
Aqp9
aquaporin 9
chr13_+_67833235 0.291 ENSMUST00000060609.7
Gm10037
predicted gene 10037
chr18_-_77047282 0.280 ENSMUST00000154665.1
ENSMUST00000026486.6
ENSMUST00000123650.1
ENSMUST00000126153.1
Katnal2



katanin p60 subunit A-like 2



chr7_+_127233227 0.269 ENSMUST00000056232.6
Zfp553
zinc finger protein 553
chr3_+_55461758 0.258 ENSMUST00000070418.4
Dclk1
doublecortin-like kinase 1
chr13_+_22043189 0.247 ENSMUST00000110452.1
Hist1h2bj
histone cluster 1, H2bj
chr8_-_34965631 0.245 ENSMUST00000033929.4
Tnks
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr18_-_77047243 0.244 ENSMUST00000137354.1
ENSMUST00000137498.1
Katnal2

katanin p60 subunit A-like 2

chr16_+_58408443 0.235 ENSMUST00000046663.7
Dcbld2
discoidin, CUB and LCCL domain containing 2
chr8_+_107031218 0.226 ENSMUST00000034388.9
Vps4a
vacuolar protein sorting 4a (yeast)
chr13_-_102905740 0.225 ENSMUST00000167462.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr13_-_22042949 0.215 ENSMUST00000091741.4
Hist1h2ag
histone cluster 1, H2ag
chr19_+_41933464 0.203 ENSMUST00000026154.7
Zdhhc16
zinc finger, DHHC domain containing 16
chr17_+_35517100 0.183 ENSMUST00000164242.2
ENSMUST00000045956.7
Cchcr1

coiled-coil alpha-helical rod protein 1

chr3_+_96268654 0.183 ENSMUST00000098843.2
Hist2h3b
histone cluster 2, H3b
chr19_+_8802486 0.172 ENSMUST00000172175.1
Zbtb3
zinc finger and BTB domain containing 3
chr4_+_136286061 0.167 ENSMUST00000069195.4
ENSMUST00000130658.1
Zfp46

zinc finger protein 46

chr4_+_108719649 0.164 ENSMUST00000178992.1
3110021N24Rik
RIKEN cDNA 3110021N24 gene
chr11_-_115276973 0.164 ENSMUST00000021078.2
Fdxr
ferredoxin reductase
chr1_+_72284367 0.157 ENSMUST00000027380.5
ENSMUST00000141783.1
Tmem169

transmembrane protein 169

chr2_+_65620829 0.129 ENSMUST00000028377.7
Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr2_-_150255591 0.128 ENSMUST00000063463.5
Gm21994
predicted gene 21994
chr18_+_38993126 0.127 ENSMUST00000097593.2
Arhgap26
Rho GTPase activating protein 26
chr15_-_79774408 0.115 ENSMUST00000023055.6
Dnal4
dynein, axonemal, light chain 4
chr19_-_41933276 0.107 ENSMUST00000075280.4
ENSMUST00000112123.2
Exosc1

exosome component 1

chr5_-_92348871 0.105 ENSMUST00000038816.6
ENSMUST00000118006.1
Cxcl10

chemokine (C-X-C motif) ligand 10

chr9_+_102720287 0.086 ENSMUST00000130602.1
Amotl2
angiomotin-like 2
chr2_-_144270852 0.078 ENSMUST00000110030.3
Snx5
sorting nexin 5
chr15_-_79774383 0.071 ENSMUST00000069877.5
Dnal4
dynein, axonemal, light chain 4
chr10_+_128083273 0.060 ENSMUST00000026459.5
Atp5b
ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit
chr13_+_55445301 0.054 ENSMUST00000001115.8
ENSMUST00000099482.3
Grk6

G protein-coupled receptor kinase 6

chr3_-_87174657 0.052 ENSMUST00000159976.1
ENSMUST00000107618.2
Kirrel

kin of IRRE like (Drosophila)

chr1_-_55226768 0.026 ENSMUST00000027121.8
ENSMUST00000114428.2
Rftn2

raftlin family member 2

chr13_-_23934156 0.020 ENSMUST00000052776.2
Hist1h2ba
histone cluster 1, H2ba
chr9_+_119063429 0.018 ENSMUST00000141185.1
ENSMUST00000126251.1
ENSMUST00000136561.1
Vill


villin-like


chr14_+_76110885 0.005 ENSMUST00000022586.1
Nufip1
nuclear fragile X mental retardation protein interacting protein 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.0 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.3 2.3 GO:0019532 oxalate transport(GO:0019532)
0.1 0.5 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 0.2 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.1 0.2 GO:0009838 abscission(GO:0009838) positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 3.1 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.1 0.7 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.8 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.3 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.3 GO:0015791 polyol transport(GO:0015791) bile acid secretion(GO:0032782)
0.0 0.1 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.0 0.8 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 1.4 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 0.1 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.0 0.2 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.3 GO:0071803 keratinocyte development(GO:0003334) positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 GO:0042555 MCM complex(GO:0042555)
0.0 0.8 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.2 GO:0090543 ESCRT III complex(GO:0000815) Flemming body(GO:0090543)
0.0 1.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.5 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.2 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 2.0 GO:0001650 fibrillar center(GO:0001650)
0.0 0.1 GO:0097422 tubular endosome(GO:0097422)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.2 2.3 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.1 0.8 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 2.0 GO:0008483 transaminase activity(GO:0008483)
0.1 0.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.3 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.3 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.5 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.8 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.1 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.2 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 0.7 PID_ATR_PATHWAY ATR signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.1 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 2.0 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 0.8 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.8 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.7 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.0 0.3 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.8 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 1.7 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.1 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease