Motif ID: Foxq1

Z-value: 1.117


Transcription factors associated with Foxq1:

Gene SymbolEntrez IDGene Name
Foxq1 ENSMUSG00000038415.8 Foxq1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxq1mm10_v2_chr13_+_31558157_315581760.067.3e-01Click!


Activity profile for motif Foxq1.

activity profile for motif Foxq1


Sorted Z-values histogram for motif Foxq1

Sorted Z-values for motif Foxq1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxq1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_30353468 10.497 ENSMUST00000112249.1
Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr16_+_43363855 10.348 ENSMUST00000156367.1
Zbtb20
zinc finger and BTB domain containing 20
chrX_-_103483205 10.054 ENSMUST00000127786.2
Xist
inactive X specific transcripts
chr16_+_43364145 8.734 ENSMUST00000148775.1
Zbtb20
zinc finger and BTB domain containing 20
chr2_-_77519565 8.055 ENSMUST00000111830.2
Zfp385b
zinc finger protein 385B
chr2_+_76406529 6.463 ENSMUST00000111929.1
ENSMUST00000077972.4
ENSMUST00000111930.2
Osbpl6


oxysterol binding protein-like 6


chr5_+_122643878 6.425 ENSMUST00000100737.3
ENSMUST00000121489.1
ENSMUST00000031425.8
ENSMUST00000086247.5
P2rx7



purinergic receptor P2X, ligand-gated ion channel, 7



chr17_+_35076902 5.863 ENSMUST00000172494.1
ENSMUST00000172678.1
ENSMUST00000013910.4
Ly6g6e


lymphocyte antigen 6 complex, locus G6E


chr5_-_122002340 5.293 ENSMUST00000134326.1
Cux2
cut-like homeobox 2
chr1_-_170110491 5.291 ENSMUST00000027985.2
Ddr2
discoidin domain receptor family, member 2
chr18_+_37496997 5.250 ENSMUST00000059571.5
Pcdhb19
protocadherin beta 19
chr4_-_87806276 5.240 ENSMUST00000148059.1
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr4_-_87806296 5.075 ENSMUST00000126353.1
ENSMUST00000149357.1
Mllt3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr18_-_89769479 4.717 ENSMUST00000097495.3
Dok6
docking protein 6
chr18_+_69344503 4.526 ENSMUST00000114985.3
Tcf4
transcription factor 4
chr19_-_28963863 4.382 ENSMUST00000161813.1
4430402I18Rik
RIKEN cDNA 4430402I18 gene
chr15_-_58214882 4.333 ENSMUST00000022986.6
Fbxo32
F-box protein 32
chr17_+_35077080 4.046 ENSMUST00000172959.1
Ly6g6e
lymphocyte antigen 6 complex, locus G6E
chr8_-_84773381 3.990 ENSMUST00000109764.1
Nfix
nuclear factor I/X
chr10_+_60106452 3.967 ENSMUST00000165024.2
Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr18_+_37442517 3.899 ENSMUST00000056915.1
Pcdhb13
protocadherin beta 13
chr18_+_57468478 3.761 ENSMUST00000091892.2
Ctxn3
cortexin 3
chr4_-_129121889 3.592 ENSMUST00000139450.1
ENSMUST00000125931.1
ENSMUST00000116444.2
Hpca


hippocalcin


chr18_+_37489465 3.516 ENSMUST00000055949.2
Pcdhb18
protocadherin beta 18
chr1_+_51289106 3.361 ENSMUST00000051572.6
Sdpr
serum deprivation response
chr18_+_37477768 3.341 ENSMUST00000051442.5
Pcdhb16
protocadherin beta 16
chr18_+_37447641 3.115 ENSMUST00000052387.3
Pcdhb14
protocadherin beta 14
chr3_+_7366598 2.822 ENSMUST00000028999.6
Pkia
protein kinase inhibitor, alpha
chr2_+_120977017 2.808 ENSMUST00000067582.7
Tmem62
transmembrane protein 62
chr7_+_19176416 2.801 ENSMUST00000117338.1
Eml2
echinoderm microtubule associated protein like 2
chr18_+_51117754 2.706 ENSMUST00000116639.2
Prr16
proline rich 16
chr5_-_99252839 2.641 ENSMUST00000168092.1
ENSMUST00000031276.8
Rasgef1b

RasGEF domain family, member 1B

chr5_-_123140135 2.633 ENSMUST00000160099.1
AI480526
expressed sequence AI480526
chr13_-_21453714 2.621 ENSMUST00000032820.7
ENSMUST00000110485.1
Zscan26

zinc finger and SCAN domain containing 26

chr14_-_36935560 2.616 ENSMUST00000183038.1
Ccser2
coiled-coil serine rich 2
chr18_+_37518341 2.501 ENSMUST00000097609.1
Pcdhb22
protocadherin beta 22
chr7_+_141476374 2.382 ENSMUST00000117634.1
Tspan4
tetraspanin 4
chr1_-_132707304 2.271 ENSMUST00000043189.7
Nfasc
neurofascin
chr13_-_67061131 2.146 ENSMUST00000167565.1
Zfp712
zinc finger protein 712
chr3_-_146781351 2.115 ENSMUST00000005164.7
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr4_+_97772734 2.090 ENSMUST00000152023.1
Nfia
nuclear factor I/A
chr13_-_67637776 2.074 ENSMUST00000012314.8
A530054K11Rik
RIKEN cDNA A530054K11 gene
chr6_-_39725448 2.046 ENSMUST00000002487.8
Braf
Braf transforming gene
chr17_-_32822200 1.953 ENSMUST00000179695.1
Zfp799
zinc finger protein 799
chr11_+_16257706 1.913 ENSMUST00000109645.2
ENSMUST00000109647.2
Vstm2a

V-set and transmembrane domain containing 2A

chr1_-_6215292 1.831 ENSMUST00000097832.1
4732440D04Rik
RIKEN cDNA 4732440D04 gene
chr4_+_139622842 1.821 ENSMUST00000039818.9
Aldh4a1
aldehyde dehydrogenase 4 family, member A1
chr19_-_43674844 1.806 ENSMUST00000046038.7
Slc25a28
solute carrier family 25, member 28
chr7_+_24134148 1.769 ENSMUST00000056549.7
Zfp235
zinc finger protein 235
chr19_-_56822161 1.743 ENSMUST00000118592.1
A630007B06Rik
RIKEN cDNA A630007B06 gene
chr15_-_89196457 1.697 ENSMUST00000078953.7
Dennd6b
DENN/MADD domain containing 6B
chr3_+_135825648 1.678 ENSMUST00000180196.1
Slc39a8
solute carrier family 39 (metal ion transporter), member 8
chr10_+_34297421 1.619 ENSMUST00000047935.6
Tspyl4
TSPY-like 4
chr10_+_69925954 1.606 ENSMUST00000181974.1
ENSMUST00000182795.1
ENSMUST00000182437.1
Ank3


ankyrin 3, epithelial


chrX_-_70365052 1.557 ENSMUST00000101509.2
Ids
iduronate 2-sulfatase
chr1_-_43098622 1.484 ENSMUST00000095014.1
Tgfbrap1
transforming growth factor, beta receptor associated protein 1
chr1_+_89454769 1.313 ENSMUST00000027521.8
ENSMUST00000074945.5
Agap1

ArfGAP with GTPase domain, ankyrin repeat and PH domain 1

chr2_-_181581996 1.293 ENSMUST00000057816.8
Uckl1
uridine-cytidine kinase 1-like 1
chr12_+_33314277 1.258 ENSMUST00000133549.1
Atxn7l1
ataxin 7-like 1
chr2_-_7395879 1.223 ENSMUST00000182404.1
Celf2
CUGBP, Elav-like family member 2
chr11_-_62392605 1.181 ENSMUST00000151498.2
ENSMUST00000159069.1
Ncor1

nuclear receptor co-repressor 1

chr12_-_101958148 1.160 ENSMUST00000159883.1
ENSMUST00000160251.1
ENSMUST00000161011.1
ENSMUST00000021606.5
Atxn3



ataxin 3



chr14_+_124005355 1.136 ENSMUST00000166105.1
Gm17615
predicted gene, 17615
chr5_-_146220901 1.122 ENSMUST00000169407.2
ENSMUST00000161331.1
ENSMUST00000159074.2
ENSMUST00000067837.3
Rnf6



ring finger protein (C3H2C3 type) 6



chr2_-_6722187 1.111 ENSMUST00000182657.1
Celf2
CUGBP, Elav-like family member 2
chr7_+_120677579 1.111 ENSMUST00000060175.6
BC030336
cDNA sequence BC030336
chr4_+_108479081 1.077 ENSMUST00000155068.1
Zcchc11
zinc finger, CCHC domain containing 11
chr6_+_42264983 1.007 ENSMUST00000031895.6
Casp2
caspase 2
chr7_+_45783883 0.999 ENSMUST00000072580.5
Lmtk3
lemur tyrosine kinase 3
chr2_+_112284561 0.998 ENSMUST00000053666.7
Slc12a6
solute carrier family 12, member 6
chr7_+_80186835 0.989 ENSMUST00000107383.1
ENSMUST00000032754.7
Sema4b

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B

chr16_+_91391721 0.983 ENSMUST00000160764.1
Gm21970
predicted gene 21970
chr11_-_107348130 0.981 ENSMUST00000134763.1
Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chr12_-_104865076 0.909 ENSMUST00000109937.1
ENSMUST00000109936.1
Clmn

calmin

chr9_-_110375430 0.854 ENSMUST00000168137.1
5830462I19Rik
RIKEN cDNA 5830462I19 gene
chr11_-_54860564 0.841 ENSMUST00000144164.1
Lyrm7
LYR motif containing 7
chr2_-_91255995 0.831 ENSMUST00000180732.1
Gm17281
predicted gene, 17281
chr7_-_100932140 0.827 ENSMUST00000107032.1
Arhgef17
Rho guanine nucleotide exchange factor (GEF) 17
chr13_+_40917626 0.808 ENSMUST00000067778.6
Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr8_+_25911670 0.762 ENSMUST00000120653.1
ENSMUST00000126226.1
Kcnu1

potassium channel, subfamily U, member 1

chr3_+_129532386 0.737 ENSMUST00000071402.2
Elovl6
ELOVL family member 6, elongation of long chain fatty acids (yeast)
chr6_-_48086530 0.704 ENSMUST00000073124.6
Zfp746
zinc finger protein 746
chr15_-_102189032 0.698 ENSMUST00000023805.1
Csad
cysteine sulfinic acid decarboxylase
chr10_+_80755196 0.697 ENSMUST00000105336.2
Dot1l
DOT1-like, histone H3 methyltransferase (S. cerevisiae)
chr1_-_195131536 0.693 ENSMUST00000075451.6
Cr1l
complement component (3b/4b) receptor 1-like
chr18_-_3281036 0.655 ENSMUST00000049942.6
ENSMUST00000139537.1
ENSMUST00000124747.1
Crem


cAMP responsive element modulator


chr3_-_36053512 0.613 ENSMUST00000166644.2
ENSMUST00000062056.8
Ccdc144b

coiled-coil domain containing 144B

chr2_+_60209887 0.600 ENSMUST00000102748.4
ENSMUST00000102747.1
March7

membrane-associated ring finger (C3HC4) 7

chrX_+_38600626 0.544 ENSMUST00000000365.2
Mcts1
malignant T cell amplified sequence 1
chr17_+_31433054 0.532 ENSMUST00000136384.1
Pde9a
phosphodiesterase 9A
chr1_+_43098710 0.504 ENSMUST00000010434.7
AI597479
expressed sequence AI597479
chr3_-_57301919 0.451 ENSMUST00000029376.8
Tm4sf1
transmembrane 4 superfamily member 1
chr7_+_24270420 0.413 ENSMUST00000108438.3
Zfp93
zinc finger protein 93
chr9_-_112187766 0.412 ENSMUST00000111872.2
ENSMUST00000164754.2
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr15_-_97247287 0.407 ENSMUST00000053106.5
Amigo2
adhesion molecule with Ig like domain 2
chr9_+_70678950 0.376 ENSMUST00000067880.6
Adam10
a disintegrin and metallopeptidase domain 10
chr9_+_50494516 0.339 ENSMUST00000114474.1
1600029D21Rik
RIKEN cDNA 1600029D21 gene
chr4_+_107314363 0.336 ENSMUST00000075693.5
ENSMUST00000139527.1
Yipf1

Yip1 domain family, member 1

chr8_+_93810832 0.336 ENSMUST00000034198.8
ENSMUST00000125716.1
Gnao1

guanine nucleotide binding protein, alpha O

chr3_+_19957037 0.315 ENSMUST00000091309.5
ENSMUST00000108329.1
ENSMUST00000003714.6
Cp


ceruloplasmin


chr4_-_119174178 0.297 ENSMUST00000106355.3
Zfp691
zinc finger protein 691
chr3_+_53488677 0.290 ENSMUST00000029307.3
Stoml3
stomatin (Epb7.2)-like 3
chr5_+_107597760 0.258 ENSMUST00000112655.1
Rpap2
RNA polymerase II associated protein 2
chr1_+_33719863 0.247 ENSMUST00000088287.3
Rab23
RAB23, member RAS oncogene family
chr3_+_79884496 0.245 ENSMUST00000118853.1
Fam198b
family with sequence similarity 198, member B
chr3_+_136670076 0.244 ENSMUST00000070198.7
Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr4_+_32243733 0.224 ENSMUST00000165661.1
D130062J21Rik
RIKEN cDNA D130062J21 gene
chr5_+_107597696 0.221 ENSMUST00000112651.1
ENSMUST00000112654.1
ENSMUST00000065422.5
Rpap2


RNA polymerase II associated protein 2


chr4_+_107314399 0.201 ENSMUST00000128284.1
ENSMUST00000124650.1
Yipf1

Yip1 domain family, member 1

chr15_+_97247011 0.145 ENSMUST00000059433.6
Pced1b
PC-esterase domain containing 1B
chr7_+_120917744 0.129 ENSMUST00000033173.7
ENSMUST00000106483.2
Polr3e

polymerase (RNA) III (DNA directed) polypeptide E

chr8_+_78509319 0.124 ENSMUST00000034111.8
Slc10a7
solute carrier family 10 (sodium/bile acid cotransporter family), member 7
chr4_-_119173849 0.102 ENSMUST00000052715.4
ENSMUST00000179290.1
ENSMUST00000154226.1
Zfp691


zinc finger protein 691


chr8_-_53638945 0.095 ENSMUST00000047768.4
Neil3
nei like 3 (E. coli)
chr16_-_92400067 0.094 ENSMUST00000023672.8
Rcan1
regulator of calcineurin 1
chr2_-_176917518 0.092 ENSMUST00000108931.2
Gm14296
predicted gene 14296
chr5_+_25247344 0.074 ENSMUST00000114950.1
Galnt11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11
chr15_+_85510812 0.069 ENSMUST00000079690.2
Gm4825
predicted pseudogene 4825
chr1_+_87404916 0.017 ENSMUST00000173152.1
ENSMUST00000173663.1
Gigyf2

GRB10 interacting GYF protein 2

chr2_-_37647199 0.004 ENSMUST00000028279.3
Strbp
spermatid perinuclear RNA binding protein

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 10.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
2.6 10.5 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
2.2 4.3 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
2.1 6.4 GO:0032650 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) interleukin-1 alpha secretion(GO:0050703) regulation of bleb assembly(GO:1904170)
1.2 3.6 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.7 5.3 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.6 10.3 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.6 1.9 GO:0070343 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
0.6 2.3 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.5 19.1 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.4 4.5 GO:0042118 endothelial cell activation(GO:0042118)
0.4 2.8 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.4 3.5 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.3 9.9 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
0.3 1.2 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.3 1.3 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.3 2.0 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.2 2.8 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.2 5.4 GO:0007614 short-term memory(GO:0007614)
0.2 1.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.2 4.0 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.2 1.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.2 1.8 GO:0006560 proline metabolic process(GO:0006560)
0.2 2.1 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.2 0.7 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.2 1.0 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.2 1.7 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.2 3.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.2 0.8 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 1.6 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 1.0 GO:0035826 rubidium ion transport(GO:0035826) cellular hypotonic response(GO:0071476)
0.1 0.5 GO:0002188 translation reinitiation(GO:0002188)
0.1 2.1 GO:0072189 ureter development(GO:0072189)
0.1 1.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 2.7 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.7 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.1 1.2 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.1 14.6 GO:0007416 synapse assembly(GO:0007416)
0.1 0.7 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.1 0.2 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) regulation of connective tissue replacement(GO:1905203)
0.1 0.8 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.4 GO:0042117 monocyte activation(GO:0042117)
0.1 7.8 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.1 0.7 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.6 GO:0002643 regulation of tolerance induction(GO:0002643)
0.1 0.5 GO:0009301 snRNA transcription(GO:0009301)
0.1 2.3 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 1.8 GO:0006826 iron ion transport(GO:0006826)
0.0 0.5 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.3 GO:0006825 copper ion transport(GO:0006825)
0.0 7.4 GO:0006869 lipid transport(GO:0006869)
0.0 0.2 GO:0006968 cellular defense response(GO:0006968)
0.0 1.0 GO:0050919 negative chemotaxis(GO:0050919)
0.0 1.7 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.7 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.1 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 10.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
1.0 10.1 GO:0000805 X chromosome(GO:0000805)
0.6 2.3 GO:0097454 Schwann cell microvillus(GO:0097454)
0.4 6.4 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.3 3.6 GO:0044327 dendritic spine head(GO:0044327)
0.2 6.8 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.2 1.5 GO:0033263 CORVET complex(GO:0033263)
0.2 10.3 GO:0008023 transcription elongation factor complex(GO:0008023)
0.2 2.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 5.8 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 1.6 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 1.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.1 0.5 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 1.2 GO:0016580 Sin3 complex(GO:0016580)
0.1 4.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 7.2 GO:0001650 fibrillar center(GO:0001650)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 2.8 GO:0072686 mitotic spindle(GO:0072686)
0.0 4.5 GO:0032993 protein-DNA complex(GO:0032993)
0.0 22.0 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 1.1 GO:0016605 PML body(GO:0016605)
0.0 1.7 GO:0055037 recycling endosome(GO:0055037)
0.0 0.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 9.9 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
1.3 10.5 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
1.1 4.5 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
1.1 6.4 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.6 5.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.5 2.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.3 0.8 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.3 1.3 GO:0004849 uridine kinase activity(GO:0004849)
0.3 0.8 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.2 1.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.2 2.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 2.8 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.2 1.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.2 1.8 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.2 1.0 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.1 1.2 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 1.0 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 25.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 1.0 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 1.6 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 1.8 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 1.0 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 2.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.7 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.3 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 3.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.3 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 9.4 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.1 0.5 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 4.3 GO:0002039 p53 binding(GO:0002039)
0.0 2.3 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 1.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 1.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.1 GO:0050681 androgen receptor binding(GO:0050681)
0.0 1.5 GO:0005158 insulin receptor binding(GO:0005158)
0.0 2.4 GO:0003823 antigen binding(GO:0003823)
0.0 1.5 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.5 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 1.6 GO:0030507 spectrin binding(GO:0030507)
0.0 3.5 GO:0005088 Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.0 0.1 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.7 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.7 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 7.7 GO:0005509 calcium ion binding(GO:0005509)
0.0 4.1 GO:0008017 microtubule binding(GO:0008017)
0.0 0.5 GO:0003743 translation initiation factor activity(GO:0003743)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 3.5 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.1 4.3 PID_FOXO_PATHWAY FoxO family signaling
0.1 1.5 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 2.1 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.0 2.1 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 3.9 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 1.0 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.3 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 1.0 PID_HIV_NEF_PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 1.2 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 6.4 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 4.5 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 2.0 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 2.1 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 1.1 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.1 1.1 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 1.6 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.0 REACTOME_NOD1_2_SIGNALING_PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 1.2 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.3 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.4 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.7 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.7 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.5 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME_PLC_BETA_MEDIATED_EVENTS Genes involved in PLC beta mediated events
0.0 0.2 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 1.8 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.8 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK