Motif ID: Hoxa13
Z-value: 0.688

Transcription factors associated with Hoxa13:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Hoxa13 | ENSMUSG00000038203.12 | Hoxa13 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 2.4 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
0.7 | 2.2 | GO:0014809 | regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
0.7 | 2.1 | GO:0099548 | drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738) retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by nitric oxide(GO:0099548) |
0.6 | 1.9 | GO:2000097 | regulation of smooth muscle cell-matrix adhesion(GO:2000097) negative regulation of lymphocyte migration(GO:2000402) |
0.4 | 0.4 | GO:0003134 | BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134) |
0.4 | 2.1 | GO:0030913 | paranodal junction assembly(GO:0030913) |
0.3 | 2.8 | GO:0090336 | positive regulation of brown fat cell differentiation(GO:0090336) |
0.3 | 1.0 | GO:0061349 | Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) hypophysis morphogenesis(GO:0048850) cervix development(GO:0060067) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) |
0.3 | 1.6 | GO:0035063 | nuclear speck organization(GO:0035063) |
0.3 | 0.9 | GO:0071918 | urea transmembrane transport(GO:0071918) |
0.3 | 0.9 | GO:0003274 | endocardial cushion fusion(GO:0003274) |
0.3 | 0.9 | GO:0043379 | memory T cell differentiation(GO:0043379) |
0.3 | 0.9 | GO:0044208 | 'de novo' AMP biosynthetic process(GO:0044208) |
0.3 | 2.8 | GO:0042572 | retinol metabolic process(GO:0042572) |
0.3 | 1.0 | GO:0007352 | zygotic specification of dorsal/ventral axis(GO:0007352) |
0.2 | 0.2 | GO:0060126 | somatotropin secreting cell differentiation(GO:0060126) |
0.2 | 0.5 | GO:0021529 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) |
0.2 | 0.4 | GO:2000825 | positive regulation of androgen receptor activity(GO:2000825) |
0.2 | 0.6 | GO:0007181 | transforming growth factor beta receptor complex assembly(GO:0007181) |
0.2 | 1.4 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
0.2 | 1.4 | GO:0031848 | protection from non-homologous end joining at telomere(GO:0031848) |
0.2 | 4.8 | GO:0032967 | positive regulation of collagen biosynthetic process(GO:0032967) |
0.2 | 0.5 | GO:2000048 | negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048) |
0.2 | 1.2 | GO:0010273 | detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169) |
0.2 | 2.7 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
0.2 | 0.5 | GO:0090327 | negative regulation of locomotion involved in locomotory behavior(GO:0090327) |
0.2 | 0.5 | GO:1903490 | regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490) |
0.2 | 0.5 | GO:0014877 | response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
0.2 | 0.8 | GO:0002457 | T cell antigen processing and presentation(GO:0002457) |
0.2 | 0.5 | GO:0035359 | negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) cell proliferation involved in heart valve development(GO:2000793) |
0.1 | 1.0 | GO:0035754 | B cell chemotaxis(GO:0035754) |
0.1 | 3.1 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
0.1 | 0.5 | GO:0072362 | regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362) |
0.1 | 0.5 | GO:0070537 | histone H2A K63-linked deubiquitination(GO:0070537) |
0.1 | 0.2 | GO:0034372 | very-low-density lipoprotein particle remodeling(GO:0034372) |
0.1 | 0.5 | GO:0070269 | pyroptosis(GO:0070269) |
0.1 | 0.5 | GO:0035470 | positive regulation of vascular wound healing(GO:0035470) regulation of vascular wound healing(GO:0061043) |
0.1 | 0.3 | GO:0060686 | negative regulation of prostatic bud formation(GO:0060686) |
0.1 | 0.4 | GO:0035609 | C-terminal protein deglutamylation(GO:0035609) |
0.1 | 1.5 | GO:1900746 | regulation of vascular endothelial growth factor signaling pathway(GO:1900746) |
0.1 | 0.3 | GO:2000314 | negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314) |
0.1 | 1.7 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065) |
0.1 | 0.6 | GO:0009405 | pathogenesis(GO:0009405) |
0.1 | 1.9 | GO:0035493 | SNARE complex assembly(GO:0035493) |
0.1 | 0.3 | GO:0097051 | establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) |
0.1 | 1.6 | GO:1901629 | AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688) regulation of presynaptic membrane organization(GO:1901629) |
0.1 | 1.0 | GO:0006228 | UTP biosynthetic process(GO:0006228) |
0.1 | 0.3 | GO:1903463 | regulation of mitotic cell cycle DNA replication(GO:1903463) |
0.1 | 0.7 | GO:0031666 | positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666) |
0.1 | 0.9 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
0.1 | 0.2 | GO:0071707 | immunoglobulin heavy chain V-D-J recombination(GO:0071707) |
0.1 | 0.5 | GO:0006290 | pyrimidine dimer repair(GO:0006290) |
0.1 | 0.2 | GO:0002430 | complement receptor mediated signaling pathway(GO:0002430) GPI anchor release(GO:0006507) |
0.1 | 1.6 | GO:0051482 | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482) |
0.1 | 0.2 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
0.1 | 1.1 | GO:0071625 | vocalization behavior(GO:0071625) |
0.1 | 0.3 | GO:0048861 | leukemia inhibitory factor signaling pathway(GO:0048861) |
0.1 | 0.4 | GO:0042270 | protection from natural killer cell mediated cytotoxicity(GO:0042270) |
0.1 | 0.2 | GO:0000973 | posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) |
0.1 | 0.5 | GO:0014816 | skeletal muscle satellite cell differentiation(GO:0014816) |
0.1 | 0.6 | GO:0042538 | hyperosmotic salinity response(GO:0042538) |
0.1 | 0.6 | GO:0035269 | protein O-linked mannosylation(GO:0035269) |
0.1 | 1.9 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
0.1 | 0.2 | GO:1990414 | replication-born double-strand break repair via sister chromatid exchange(GO:1990414) |
0.1 | 0.4 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
0.1 | 1.8 | GO:0095500 | acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145) |
0.1 | 0.7 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
0.1 | 0.2 | GO:0008594 | photoreceptor cell morphogenesis(GO:0008594) |
0.1 | 0.2 | GO:0032058 | positive regulation of translational initiation in response to stress(GO:0032058) |
0.1 | 0.9 | GO:0007379 | segment specification(GO:0007379) |
0.1 | 0.7 | GO:0000729 | DNA double-strand break processing(GO:0000729) |
0.1 | 0.2 | GO:0000733 | DNA strand renaturation(GO:0000733) |
0.1 | 0.4 | GO:0016584 | nucleosome positioning(GO:0016584) |
0.0 | 0.6 | GO:0097186 | amelogenesis(GO:0097186) |
0.0 | 0.1 | GO:0002934 | desmosome organization(GO:0002934) |
0.0 | 1.7 | GO:0035458 | cellular response to interferon-beta(GO:0035458) |
0.0 | 1.0 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
0.0 | 0.5 | GO:0015838 | proline transport(GO:0015824) amino-acid betaine transport(GO:0015838) |
0.0 | 1.8 | GO:0046677 | response to antibiotic(GO:0046677) |
0.0 | 0.4 | GO:0070995 | NADPH oxidation(GO:0070995) |
0.0 | 0.5 | GO:0010839 | negative regulation of keratinocyte proliferation(GO:0010839) |
0.0 | 2.3 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
0.0 | 0.9 | GO:0060252 | positive regulation of glial cell proliferation(GO:0060252) |
0.0 | 0.1 | GO:0090400 | stress-induced premature senescence(GO:0090400) |
0.0 | 0.2 | GO:0071894 | histone H2B conserved C-terminal lysine ubiquitination(GO:0071894) |
0.0 | 1.1 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
0.0 | 3.1 | GO:0046847 | filopodium assembly(GO:0046847) |
0.0 | 0.8 | GO:0040034 | regulation of development, heterochronic(GO:0040034) |
0.0 | 0.5 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
0.0 | 0.1 | GO:0042726 | flavin-containing compound metabolic process(GO:0042726) |
0.0 | 0.2 | GO:0018242 | protein O-linked glycosylation via serine(GO:0018242) |
0.0 | 0.2 | GO:0046864 | retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865) alveolar primary septum development(GO:0061143) paramesonephric duct development(GO:0061205) |
0.0 | 0.3 | GO:0006013 | mannose metabolic process(GO:0006013) |
0.0 | 0.8 | GO:0047497 | establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) |
0.0 | 0.6 | GO:0060218 | hematopoietic stem cell differentiation(GO:0060218) |
0.0 | 0.5 | GO:0061158 | 3'-UTR-mediated mRNA destabilization(GO:0061158) |
0.0 | 0.2 | GO:0036089 | cleavage furrow formation(GO:0036089) |
0.0 | 0.4 | GO:0046697 | decidualization(GO:0046697) |
0.0 | 0.8 | GO:0097352 | autophagosome maturation(GO:0097352) |
0.0 | 0.1 | GO:0019441 | tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) quinolinate biosynthetic process(GO:0019805) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218) kynurenine metabolic process(GO:0070189) |
0.0 | 0.1 | GO:1904211 | membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211) |
0.0 | 0.6 | GO:0035855 | megakaryocyte development(GO:0035855) |
0.0 | 0.3 | GO:0010459 | negative regulation of heart rate(GO:0010459) |
0.0 | 0.2 | GO:0000707 | meiotic DNA recombinase assembly(GO:0000707) |
0.0 | 0.2 | GO:0006390 | transcription from mitochondrial promoter(GO:0006390) |
0.0 | 1.5 | GO:0042773 | ATP synthesis coupled electron transport(GO:0042773) |
0.0 | 0.1 | GO:0006106 | fumarate metabolic process(GO:0006106) |
0.0 | 0.7 | GO:0007608 | sensory perception of smell(GO:0007608) |
0.0 | 0.1 | GO:0060613 | fat pad development(GO:0060613) |
0.0 | 0.9 | GO:0000038 | very long-chain fatty acid metabolic process(GO:0000038) |
0.0 | 0.2 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
0.0 | 0.2 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
0.0 | 0.2 | GO:0044791 | modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) |
0.0 | 0.4 | GO:0061157 | mRNA destabilization(GO:0061157) |
0.0 | 0.4 | GO:0043968 | histone H2A acetylation(GO:0043968) |
0.0 | 0.3 | GO:0042640 | anagen(GO:0042640) |
0.0 | 0.2 | GO:0015809 | arginine transport(GO:0015809) |
0.0 | 0.3 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
0.0 | 0.2 | GO:0060363 | cranial suture morphogenesis(GO:0060363) |
0.0 | 0.3 | GO:0000338 | protein deneddylation(GO:0000338) |
0.0 | 0.3 | GO:0009083 | branched-chain amino acid catabolic process(GO:0009083) |
0.0 | 0.2 | GO:0046688 | response to copper ion(GO:0046688) |
0.0 | 0.4 | GO:0001522 | pseudouridine synthesis(GO:0001522) |
0.0 | 0.6 | GO:0097120 | receptor localization to synapse(GO:0097120) |
0.0 | 0.1 | GO:1902998 | macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998) |
0.0 | 0.5 | GO:0030488 | tRNA methylation(GO:0030488) |
0.0 | 1.0 | GO:0006749 | glutathione metabolic process(GO:0006749) |
0.0 | 0.9 | GO:0035914 | skeletal muscle cell differentiation(GO:0035914) |
0.0 | 0.1 | GO:0090527 | actin filament reorganization(GO:0090527) |
0.0 | 0.1 | GO:1904667 | negative regulation of ubiquitin protein ligase activity(GO:1904667) |
0.0 | 0.2 | GO:0007602 | phototransduction(GO:0007602) |
0.0 | 0.3 | GO:1902230 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230) |
0.0 | 0.1 | GO:0019227 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
0.0 | 0.5 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
0.0 | 0.6 | GO:0033120 | positive regulation of RNA splicing(GO:0033120) |
0.0 | 0.1 | GO:1903566 | positive regulation of protein localization to cilium(GO:1903566) |
0.0 | 0.3 | GO:0008299 | isoprenoid biosynthetic process(GO:0008299) |
0.0 | 0.5 | GO:0006506 | GPI anchor biosynthetic process(GO:0006506) |
0.0 | 0.1 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
0.0 | 0.4 | GO:0046329 | negative regulation of JNK cascade(GO:0046329) |
0.0 | 0.3 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
0.0 | 0.3 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.6 | 4.8 | GO:0038045 | large latent transforming growth factor-beta complex(GO:0038045) |
0.8 | 2.4 | GO:0005588 | collagen type V trimer(GO:0005588) |
0.8 | 2.3 | GO:0030868 | smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425) |
0.4 | 1.9 | GO:0070820 | tertiary granule(GO:0070820) |
0.3 | 1.7 | GO:0005587 | collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651) |
0.2 | 2.1 | GO:0042582 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
0.2 | 0.6 | GO:0034673 | inhibin-betaglycan-ActRII complex(GO:0034673) |
0.2 | 0.7 | GO:0008623 | CHRAC(GO:0008623) |
0.2 | 1.1 | GO:0097513 | myosin II filament(GO:0097513) |
0.2 | 0.2 | GO:0031467 | Cul7-RING ubiquitin ligase complex(GO:0031467) |
0.1 | 0.6 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
0.1 | 2.2 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
0.1 | 1.4 | GO:0098644 | complex of collagen trimers(GO:0098644) |
0.1 | 0.5 | GO:0061702 | inflammasome complex(GO:0061702) |
0.1 | 1.0 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
0.1 | 0.8 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
0.1 | 1.9 | GO:0032279 | asymmetric synapse(GO:0032279) |
0.1 | 0.5 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
0.1 | 0.5 | GO:0070531 | BRCA1-A complex(GO:0070531) |
0.1 | 0.4 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
0.1 | 0.5 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
0.1 | 0.2 | GO:0072534 | perineuronal net(GO:0072534) |
0.1 | 0.3 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
0.1 | 2.5 | GO:0016235 | aggresome(GO:0016235) |
0.0 | 1.6 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
0.0 | 0.6 | GO:0031209 | SCAR complex(GO:0031209) |
0.0 | 0.2 | GO:0032983 | kainate selective glutamate receptor complex(GO:0032983) |
0.0 | 0.5 | GO:0070938 | contractile ring(GO:0070938) |
0.0 | 0.2 | GO:0044615 | nuclear pore nuclear basket(GO:0044615) |
0.0 | 0.5 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
0.0 | 0.2 | GO:0033063 | Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
0.0 | 0.4 | GO:0070419 | nonhomologous end joining complex(GO:0070419) |
0.0 | 3.2 | GO:0000118 | histone deacetylase complex(GO:0000118) |
0.0 | 0.4 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
0.0 | 0.2 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
0.0 | 0.1 | GO:0032437 | cuticular plate(GO:0032437) |
0.0 | 0.2 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
0.0 | 0.8 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
0.0 | 0.3 | GO:0030056 | hemidesmosome(GO:0030056) |
0.0 | 2.1 | GO:0070469 | respiratory chain(GO:0070469) |
0.0 | 0.3 | GO:0042788 | polysomal ribosome(GO:0042788) |
0.0 | 0.4 | GO:1990635 | proximal dendrite(GO:1990635) |
0.0 | 1.0 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
0.0 | 0.4 | GO:0045120 | pronucleus(GO:0045120) |
0.0 | 0.2 | GO:0042555 | MCM complex(GO:0042555) |
0.0 | 0.2 | GO:0016442 | RISC complex(GO:0016442) RNAi effector complex(GO:0031332) |
0.0 | 0.6 | GO:0060077 | inhibitory synapse(GO:0060077) |
0.0 | 0.7 | GO:0008180 | COP9 signalosome(GO:0008180) |
0.0 | 3.9 | GO:0009897 | external side of plasma membrane(GO:0009897) |
0.0 | 0.2 | GO:0031011 | Ino80 complex(GO:0031011) |
0.0 | 0.2 | GO:0005922 | connexon complex(GO:0005922) |
0.0 | 0.1 | GO:0030289 | protein phosphatase 4 complex(GO:0030289) |
0.0 | 0.3 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
0.0 | 0.3 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
0.0 | 0.5 | GO:0005657 | replication fork(GO:0005657) |
0.0 | 1.0 | GO:0030175 | filopodium(GO:0030175) |
0.0 | 0.1 | GO:0042589 | zymogen granule membrane(GO:0042589) |
0.0 | 0.4 | GO:0000788 | nuclear nucleosome(GO:0000788) |
0.0 | 0.3 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
0.0 | 0.2 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.2 | 4.8 | GO:0050436 | microfibril binding(GO:0050436) |
0.7 | 2.1 | GO:0004517 | nitric-oxide synthase activity(GO:0004517) |
0.6 | 2.3 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
0.4 | 2.8 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
0.4 | 1.5 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
0.3 | 2.1 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
0.3 | 1.0 | GO:0005110 | frizzled-2 binding(GO:0005110) |
0.2 | 0.9 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
0.2 | 0.7 | GO:0017150 | tRNA dihydrouridine synthase activity(GO:0017150) |
0.2 | 0.6 | GO:0036361 | racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661) |
0.2 | 1.8 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
0.2 | 0.7 | GO:0016230 | sphingomyelin phosphodiesterase activator activity(GO:0016230) |
0.2 | 1.1 | GO:0004984 | olfactory receptor activity(GO:0004984) |
0.2 | 1.0 | GO:0003854 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) |
0.2 | 1.1 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915) |
0.2 | 0.5 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
0.2 | 0.9 | GO:0015204 | urea transmembrane transporter activity(GO:0015204) |
0.1 | 0.4 | GO:0001129 | RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132) |
0.1 | 0.6 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
0.1 | 0.6 | GO:0051377 | mannose-ethanolamine phosphotransferase activity(GO:0051377) |
0.1 | 1.0 | GO:0070697 | activin receptor binding(GO:0070697) |
0.1 | 2.8 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
0.1 | 2.2 | GO:0017166 | vinculin binding(GO:0017166) |
0.1 | 0.4 | GO:0016262 | protein N-acetylglucosaminyltransferase activity(GO:0016262) |
0.1 | 0.4 | GO:0035673 | oligopeptide transmembrane transporter activity(GO:0035673) |
0.1 | 0.8 | GO:0032453 | histone demethylase activity (H3-K4 specific)(GO:0032453) |
0.1 | 0.5 | GO:0004966 | galanin receptor activity(GO:0004966) |
0.1 | 0.6 | GO:0005114 | type II transforming growth factor beta receptor binding(GO:0005114) |
0.1 | 0.4 | GO:0004921 | interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970) |
0.1 | 0.8 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
0.1 | 0.8 | GO:0035312 | 5'-3' exodeoxyribonuclease activity(GO:0035312) |
0.1 | 0.3 | GO:0016812 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812) |
0.1 | 0.9 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
0.1 | 0.6 | GO:1901612 | phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612) |
0.1 | 0.4 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
0.1 | 0.5 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
0.1 | 0.2 | GO:0004534 | 5'-3' exoribonuclease activity(GO:0004534) |
0.1 | 0.4 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
0.1 | 0.3 | GO:0043125 | ErbB-3 class receptor binding(GO:0043125) |
0.1 | 0.9 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) |
0.1 | 1.1 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
0.1 | 0.2 | GO:0031752 | D5 dopamine receptor binding(GO:0031752) |
0.1 | 0.3 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
0.1 | 2.4 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
0.1 | 0.5 | GO:0035033 | histone deacetylase regulator activity(GO:0035033) |
0.1 | 1.6 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
0.1 | 0.3 | GO:0017116 | single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) |
0.1 | 1.8 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.1 | 0.4 | GO:0019211 | phosphatase activator activity(GO:0019211) |
0.1 | 0.5 | GO:0015193 | L-proline transmembrane transporter activity(GO:0015193) |
0.1 | 0.6 | GO:0050733 | RS domain binding(GO:0050733) |
0.1 | 0.2 | GO:0000179 | rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) |
0.1 | 0.3 | GO:0038132 | neuregulin binding(GO:0038132) |
0.1 | 0.4 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
0.1 | 0.9 | GO:0050811 | GABA-A receptor activity(GO:0004890) GABA receptor binding(GO:0050811) |
0.0 | 1.0 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
0.0 | 2.3 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
0.0 | 0.1 | GO:0008310 | single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310) |
0.0 | 0.6 | GO:0015643 | toxic substance binding(GO:0015643) |
0.0 | 1.9 | GO:0005484 | SNAP receptor activity(GO:0005484) |
0.0 | 0.5 | GO:0015347 | sodium-independent organic anion transmembrane transporter activity(GO:0015347) |
0.0 | 0.7 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
0.0 | 0.2 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
0.0 | 1.5 | GO:0008028 | monocarboxylic acid transmembrane transporter activity(GO:0008028) |
0.0 | 0.2 | GO:0009378 | four-way junction helicase activity(GO:0009378) |
0.0 | 0.2 | GO:0034186 | apolipoprotein A-I binding(GO:0034186) |
0.0 | 0.4 | GO:0032564 | dATP binding(GO:0032564) |
0.0 | 1.9 | GO:0015485 | cholesterol binding(GO:0015485) |
0.0 | 0.4 | GO:0015093 | ferrous iron transmembrane transporter activity(GO:0015093) |
0.0 | 3.5 | GO:0033613 | activating transcription factor binding(GO:0033613) |
0.0 | 0.2 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
0.0 | 0.9 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
0.0 | 2.3 | GO:0004004 | RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) |
0.0 | 0.1 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
0.0 | 0.4 | GO:0070513 | death domain binding(GO:0070513) |
0.0 | 0.2 | GO:0015181 | arginine transmembrane transporter activity(GO:0015181) |
0.0 | 0.3 | GO:0005229 | intracellular calcium activated chloride channel activity(GO:0005229) |
0.0 | 0.5 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
0.0 | 0.2 | GO:0036310 | annealing helicase activity(GO:0036310) |
0.0 | 0.2 | GO:0000150 | recombinase activity(GO:0000150) |
0.0 | 0.2 | GO:0004630 | phospholipase D activity(GO:0004630) |
0.0 | 0.4 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
0.0 | 1.4 | GO:0005518 | collagen binding(GO:0005518) |
0.0 | 0.4 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
0.0 | 0.5 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
0.0 | 0.3 | GO:0004559 | alpha-mannosidase activity(GO:0004559) |
0.0 | 2.1 | GO:0005178 | integrin binding(GO:0005178) |
0.0 | 1.1 | GO:0030507 | spectrin binding(GO:0030507) |
0.0 | 0.3 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
0.0 | 0.5 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
0.0 | 0.1 | GO:0000832 | inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724) |
0.0 | 0.1 | GO:0004784 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
0.0 | 0.2 | GO:0000400 | four-way junction DNA binding(GO:0000400) |
0.0 | 0.2 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
0.0 | 0.5 | GO:0071837 | HMG box domain binding(GO:0071837) |
0.0 | 0.5 | GO:0031690 | adrenergic receptor binding(GO:0031690) |
0.0 | 0.6 | GO:0008175 | tRNA methyltransferase activity(GO:0008175) |
0.0 | 0.2 | GO:0003746 | translation elongation factor activity(GO:0003746) |
0.0 | 0.1 | GO:0004954 | icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955) |
0.0 | 0.0 | GO:0008502 | melatonin receptor activity(GO:0008502) |
0.0 | 0.1 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
0.0 | 0.4 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
0.0 | 0.3 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.0 | 0.5 | GO:0003684 | damaged DNA binding(GO:0003684) |
0.0 | 0.2 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
0.0 | 0.4 | GO:0001671 | ATPase activator activity(GO:0001671) |
0.0 | 0.1 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
0.0 | 0.5 | GO:0030332 | cyclin binding(GO:0030332) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 4.2 | NABA_COLLAGENS | Genes encoding collagen proteins |
0.1 | 1.1 | PID_LPA4_PATHWAY | LPA4-mediated signaling events |
0.1 | 2.2 | PID_ARF6_PATHWAY | Arf6 signaling events |
0.0 | 2.2 | PID_NCADHERIN_PATHWAY | N-cadherin signaling events |
0.0 | 1.4 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
0.0 | 1.6 | PID_ATM_PATHWAY | ATM pathway |
0.0 | 1.0 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
0.0 | 0.9 | PID_GLYPICAN_1PATHWAY | Glypican 1 network |
0.0 | 1.8 | PID_A6B1_A6B4_INTEGRIN_PATHWAY | a6b1 and a6b4 Integrin signaling |
0.0 | 4.4 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
0.0 | 1.4 | PID_BMP_PATHWAY | BMP receptor signaling |
0.0 | 0.6 | PID_INSULIN_GLUCOSE_PATHWAY | Insulin-mediated glucose transport |
0.0 | 1.0 | PID_NETRIN_PATHWAY | Netrin-mediated signaling events |
0.0 | 0.5 | PID_HEDGEHOG_2PATHWAY | Signaling events mediated by the Hedgehog family |
0.0 | 1.4 | PID_FOXO_PATHWAY | FoxO family signaling |
0.0 | 0.2 | PID_S1P_S1P4_PATHWAY | S1P4 pathway |
0.0 | 0.5 | PID_VEGFR1_PATHWAY | VEGFR1 specific signals |
0.0 | 1.3 | PID_HES_HEY_PATHWAY | Notch-mediated HES/HEY network |
0.0 | 0.6 | PID_MYC_REPRESS_PATHWAY | Validated targets of C-MYC transcriptional repression |
0.0 | 0.8 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
0.0 | 0.2 | PID_RHODOPSIN_PATHWAY | Visual signal transduction: Rods |
0.0 | 0.4 | PID_HDAC_CLASSIII_PATHWAY | Signaling events mediated by HDAC Class III |
0.0 | 0.6 | PID_ECADHERIN_NASCENT_AJ_PATHWAY | E-cadherin signaling in the nascent adherens junction |
0.0 | 0.7 | PID_TNF_PATHWAY | TNF receptor signaling pathway |
0.0 | 1.1 | PID_AR_PATHWAY | Coregulation of Androgen receptor activity |
0.0 | 0.2 | PID_UPA_UPAR_PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
0.0 | 0.4 | PID_TGFBR_PATHWAY | TGF-beta receptor signaling |
0.0 | 1.4 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.0 | 0.3 | PID_INTEGRIN_A4B1_PATHWAY | Alpha4 beta1 integrin signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.9 | REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
0.1 | 1.0 | REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
0.1 | 1.0 | REACTOME_P2Y_RECEPTORS | Genes involved in P2Y receptors |
0.1 | 1.4 | REACTOME_CS_DS_DEGRADATION | Genes involved in CS/DS degradation |
0.1 | 4.3 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
0.1 | 2.2 | REACTOME_STRIATED_MUSCLE_CONTRACTION | Genes involved in Striated Muscle Contraction |
0.1 | 1.9 | REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
0.1 | 2.1 | REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
0.1 | 2.8 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
0.1 | 2.0 | REACTOME_MYOGENESIS | Genes involved in Myogenesis |
0.0 | 1.4 | REACTOME_SIGNALING_BY_BMP | Genes involved in Signaling by BMP |
0.0 | 0.9 | REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS | Genes involved in Amine compound SLC transporters |
0.0 | 0.9 | REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
0.0 | 0.2 | REACTOME_OLFACTORY_SIGNALING_PATHWAY | Genes involved in Olfactory Signaling Pathway |
0.0 | 1.1 | REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
0.0 | 0.1 | REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS | Genes involved in Eicosanoid ligand-binding receptors |
0.0 | 0.5 | REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
0.0 | 0.5 | REACTOME_INFLAMMASOMES | Genes involved in Inflammasomes |
0.0 | 0.3 | REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
0.0 | 0.2 | REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS | Genes involved in Thrombin signalling through proteinase activated receptors (PARs) |
0.0 | 0.5 | REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
0.0 | 0.7 | REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
0.0 | 0.4 | REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX | Genes involved in Degradation of the extracellular matrix |
0.0 | 0.8 | REACTOME_ENOS_ACTIVATION_AND_REGULATION | Genes involved in eNOS activation and regulation |
0.0 | 0.3 | REACTOME_IL_7_SIGNALING | Genes involved in Interleukin-7 signaling |
0.0 | 0.6 | REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
0.0 | 0.5 | REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER | Genes involved in Formation of incision complex in GG-NER |
0.0 | 0.4 | REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
0.0 | 0.5 | REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
0.0 | 0.2 | REACTOME_HDL_MEDIATED_LIPID_TRANSPORT | Genes involved in HDL-mediated lipid transport |
0.0 | 0.2 | REACTOME_GAP_JUNCTION_ASSEMBLY | Genes involved in Gap junction assembly |
0.0 | 0.2 | REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP | Genes involved in Destabilization of mRNA by KSRP |
0.0 | 0.4 | REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |
0.0 | 0.6 | REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
0.0 | 0.2 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
0.0 | 1.1 | REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ | Genes involved in Response to elevated platelet cytosolic Ca2+ |
0.0 | 0.6 | REACTOME_GLYCOLYSIS | Genes involved in Glycolysis |
0.0 | 0.6 | REACTOME_MRNA_3_END_PROCESSING | Genes involved in mRNA 3'-end processing |
0.0 | 0.1 | REACTOME_TRYPTOPHAN_CATABOLISM | Genes involved in Tryptophan catabolism |