Motif ID: Foxf2

Z-value: 0.635


Transcription factors associated with Foxf2:

Gene SymbolEntrez IDGene Name
Foxf2 ENSMUSG00000038402.2 Foxf2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxf2mm10_v2_chr13_+_31625802_316258160.124.5e-01Click!


Activity profile for motif Foxf2.

activity profile for motif Foxf2


Sorted Z-values histogram for motif Foxf2

Sorted Z-values for motif Foxf2



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxf2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_66969616 6.021 ENSMUST00000170903.1
ENSMUST00000166420.1
ENSMUST00000005256.6
ENSMUST00000164070.1
Ndrg1



N-myc downstream regulated gene 1



chr6_-_148444336 3.046 ENSMUST00000060095.8
ENSMUST00000100772.3
Tmtc1

transmembrane and tetratricopeptide repeat containing 1

chr8_-_84773381 2.233 ENSMUST00000109764.1
Nfix
nuclear factor I/X
chr4_+_101507947 1.750 ENSMUST00000149047.1
ENSMUST00000106929.3
Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr7_+_82175156 1.451 ENSMUST00000180243.1
Sh3gl3
SH3-domain GRB2-like 3
chr7_+_30291941 1.372 ENSMUST00000144508.1
Clip3
CAP-GLY domain containing linker protein 3
chr10_+_60106452 1.369 ENSMUST00000165024.2
Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr4_+_101507855 1.364 ENSMUST00000038207.5
Dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr16_-_34263179 1.357 ENSMUST00000114949.1
ENSMUST00000114954.1
Kalrn

kalirin, RhoGEF kinase

chr1_-_87573825 1.347 ENSMUST00000068681.5
Ngef
neuronal guanine nucleotide exchange factor
chr16_-_22439570 1.319 ENSMUST00000170393.1
Etv5
ets variant gene 5
chr12_-_112511136 1.236 ENSMUST00000066791.5
Tmem179
transmembrane protein 179
chr1_+_179546303 1.177 ENSMUST00000040706.8
Cnst
consortin, connexin sorting protein
chr7_-_4844665 1.165 ENSMUST00000066041.5
ENSMUST00000172377.1
Shisa7

shisa homolog 7 (Xenopus laevis)

chr1_+_34005872 1.091 ENSMUST00000182296.1
Dst
dystonin
chr16_+_91269759 1.073 ENSMUST00000056882.5
Olig1
oligodendrocyte transcription factor 1
chr7_+_30291659 1.019 ENSMUST00000014065.8
ENSMUST00000150892.1
ENSMUST00000126216.1
Clip3


CAP-GLY domain containing linker protein 3


chr2_+_112265809 0.869 ENSMUST00000110991.2
Slc12a6
solute carrier family 12, member 6
chr16_-_34262945 0.857 ENSMUST00000114953.1
Kalrn
kalirin, RhoGEF kinase
chr8_+_58912257 0.818 ENSMUST00000160055.1
BC030500
cDNA sequence BC030500
chr8_-_125492710 0.817 ENSMUST00000108775.1
Sipa1l2
signal-induced proliferation-associated 1 like 2
chr2_+_28641227 0.761 ENSMUST00000028155.5
ENSMUST00000113869.1
ENSMUST00000113867.2
Tsc1


tuberous sclerosis 1


chr10_-_41303171 0.759 ENSMUST00000043814.3
Fig4
FIG4 homolog (S. cerevisiae)
chr16_-_4880284 0.748 ENSMUST00000037843.6
Ubald1
UBA-like domain containing 1
chr14_+_26514554 0.722 ENSMUST00000104927.1
Gm2178
predicted gene 2178
chr5_-_103211251 0.707 ENSMUST00000060871.5
ENSMUST00000112846.1
ENSMUST00000170792.1
ENSMUST00000112847.2
Mapk10



mitogen-activated protein kinase 10



chr4_+_5724304 0.697 ENSMUST00000108380.1
Fam110b
family with sequence similarity 110, member B
chr9_-_48835932 0.679 ENSMUST00000093852.3
Zbtb16
zinc finger and BTB domain containing 16
chr7_+_45783686 0.658 ENSMUST00000118564.1
ENSMUST00000133428.1
Lmtk3

lemur tyrosine kinase 3

chr11_+_69095217 0.639 ENSMUST00000101004.2
Per1
period circadian clock 1
chr13_+_60602182 0.621 ENSMUST00000044083.7
Dapk1
death associated protein kinase 1
chr19_+_44992127 0.616 ENSMUST00000179305.1
Sema4g
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr9_+_110333402 0.589 ENSMUST00000133114.1
ENSMUST00000125759.1
Scap

SREBF chaperone

chr12_+_84451485 0.568 ENSMUST00000137170.1
Lin52
lin-52 homolog (C. elegans)
chr7_+_45783883 0.566 ENSMUST00000072580.5
Lmtk3
lemur tyrosine kinase 3
chr10_+_40349265 0.552 ENSMUST00000044672.4
ENSMUST00000095743.2
Cdk19

cyclin-dependent kinase 19

chr16_-_22439719 0.542 ENSMUST00000079601.6
Etv5
ets variant gene 5
chr17_+_70522149 0.536 ENSMUST00000140728.1
Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr4_-_118409219 0.535 ENSMUST00000075406.5
Szt2
seizure threshold 2
chr8_+_93810832 0.531 ENSMUST00000034198.8
ENSMUST00000125716.1
Gnao1

guanine nucleotide binding protein, alpha O

chr6_-_39725193 0.531 ENSMUST00000101497.3
Braf
Braf transforming gene
chr17_+_70522083 0.499 ENSMUST00000148486.1
ENSMUST00000133717.1
Dlgap1

discs, large (Drosophila) homolog-associated protein 1

chr3_-_144202300 0.496 ENSMUST00000121796.1
ENSMUST00000121112.1
Lmo4

LIM domain only 4

chr12_-_15816762 0.488 ENSMUST00000020922.7
Trib2
tribbles homolog 2 (Drosophila)
chr7_-_98145472 0.485 ENSMUST00000098281.2
Omp
olfactory marker protein
chr11_-_100397740 0.471 ENSMUST00000001592.8
ENSMUST00000107403.1
Jup

junction plakoglobin

chr8_-_84237042 0.457 ENSMUST00000039480.5
Zswim4
zinc finger SWIM-type containing 4
chr18_+_34758890 0.445 ENSMUST00000049281.5
Fam53c
family with sequence similarity 53, member C
chr5_-_99252839 0.437 ENSMUST00000168092.1
ENSMUST00000031276.8
Rasgef1b

RasGEF domain family, member 1B

chr11_+_114851142 0.434 ENSMUST00000133245.1
ENSMUST00000122967.2
Gprc5c

G protein-coupled receptor, family C, group 5, member C

chr2_-_71367749 0.431 ENSMUST00000151937.1
Slc25a12
solute carrier family 25 (mitochondrial carrier, Aralar), member 12
chr18_+_34759551 0.413 ENSMUST00000097622.3
Fam53c
family with sequence similarity 53, member C
chr2_+_91730127 0.398 ENSMUST00000099712.3
ENSMUST00000111317.2
ENSMUST00000111316.2
ENSMUST00000045705.7
Ambra1



autophagy/beclin 1 regulator 1



chr11_+_118433826 0.374 ENSMUST00000106286.1
C1qtnf1
C1q and tumor necrosis factor related protein 1
chr12_-_84450944 0.369 ENSMUST00000085192.5
Aldh6a1
aldehyde dehydrogenase family 6, subfamily A1
chr2_+_112284561 0.368 ENSMUST00000053666.7
Slc12a6
solute carrier family 12, member 6
chr1_+_43445736 0.364 ENSMUST00000086421.5
ENSMUST00000114744.1
Nck2

non-catalytic region of tyrosine kinase adaptor protein 2

chr7_-_44849075 0.363 ENSMUST00000047085.8
Tbc1d17
TBC1 domain family, member 17
chr1_-_195131536 0.347 ENSMUST00000075451.6
Cr1l
complement component (3b/4b) receptor 1-like
chr6_-_83831736 0.336 ENSMUST00000058383.8
Paip2b
poly(A) binding protein interacting protein 2B
chr2_-_168601620 0.326 ENSMUST00000171689.1
ENSMUST00000137451.1
Nfatc2

nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2

chr1_+_131970589 0.317 ENSMUST00000027695.6
Slc45a3
solute carrier family 45, member 3
chr5_+_118560719 0.305 ENSMUST00000100816.4
Med13l
mediator complex subunit 13-like
chr7_+_44849581 0.304 ENSMUST00000150335.1
ENSMUST00000107882.1
Akt1s1

AKT1 substrate 1 (proline-rich)

chr7_+_130692532 0.288 ENSMUST00000033141.6
Tacc2
transforming, acidic coiled-coil containing protein 2
chr11_-_54956047 0.275 ENSMUST00000155316.1
ENSMUST00000108889.3
ENSMUST00000126703.1
Tnip1


TNFAIP3 interacting protein 1


chr7_+_44849216 0.274 ENSMUST00000054343.8
Akt1s1
AKT1 substrate 1 (proline-rich)
chr2_-_163645125 0.245 ENSMUST00000017851.3
Serinc3
serine incorporator 3
chr5_+_107437908 0.235 ENSMUST00000094541.2
Btbd8
BTB (POZ) domain containing 8
chr8_+_86745679 0.224 ENSMUST00000098532.2
Gm10638
predicted gene 10638
chr2_+_176236860 0.217 ENSMUST00000166464.1
2210418O10Rik
RIKEN cDNA 2210418O10 gene
chr7_+_44848991 0.208 ENSMUST00000107885.1
Akt1s1
AKT1 substrate 1 (proline-rich)
chr5_-_92348871 0.203 ENSMUST00000038816.6
ENSMUST00000118006.1
Cxcl10

chemokine (C-X-C motif) ligand 10

chr11_-_50210765 0.177 ENSMUST00000143379.1
ENSMUST00000015981.5
ENSMUST00000102774.4
Sqstm1


sequestosome 1


chr19_+_7056731 0.173 ENSMUST00000040261.5
Macrod1
MACRO domain containing 1
chr10_+_79716588 0.159 ENSMUST00000099513.1
ENSMUST00000020581.2
Hcn2

hyperpolarization-activated, cyclic nucleotide-gated K+ 2

chr5_+_65131184 0.157 ENSMUST00000031089.5
ENSMUST00000101191.3
Klhl5

kelch-like 5

chr12_+_69296676 0.141 ENSMUST00000021362.4
Klhdc2
kelch domain containing 2
chr9_-_108649349 0.126 ENSMUST00000013338.8
Arih2
ariadne homolog 2 (Drosophila)
chr11_-_120990871 0.115 ENSMUST00000154483.1
Csnk1d
casein kinase 1, delta
chr2_-_170406501 0.106 ENSMUST00000154650.1
Bcas1
breast carcinoma amplified sequence 1
chr13_+_46669517 0.096 ENSMUST00000099547.3
C78339
expressed sequence C78339
chrX_+_163911401 0.093 ENSMUST00000140845.1
Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr3_-_106167564 0.091 ENSMUST00000063062.8
Chi3l3
chitinase 3-like 3
chr7_+_90426312 0.078 ENSMUST00000061391.7
Ccdc89
coiled-coil domain containing 89
chr11_+_85311232 0.077 ENSMUST00000020835.9
Ppm1d
protein phosphatase 1D magnesium-dependent, delta isoform
chr7_-_90129339 0.074 ENSMUST00000181189.1
2310010J17Rik
RIKEN cDNA 2310010J17 gene
chr19_-_17837620 0.065 ENSMUST00000025618.8
ENSMUST00000050715.8
Pcsk5

proprotein convertase subtilisin/kexin type 5

chr17_+_47505211 0.058 ENSMUST00000182935.1
ENSMUST00000182506.1
Ccnd3

cyclin D3

chr19_-_4012656 0.057 ENSMUST00000134479.1
ENSMUST00000128787.1
ENSMUST00000133474.1
ENSMUST00000136921.1
ENSMUST00000042497.7
Ndufv1




NADH dehydrogenase (ubiquinone) flavoprotein 1




chr15_+_3270767 0.054 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
Sepp1



selenoprotein P, plasma, 1



chr14_+_111675113 0.046 ENSMUST00000042767.7
Slitrk5
SLIT and NTRK-like family, member 5
chr2_-_181578906 0.045 ENSMUST00000136875.1
Uckl1
uridine-cytidine kinase 1-like 1
chr10_+_126978690 0.045 ENSMUST00000105256.2
Ctdsp2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr9_+_47530173 0.040 ENSMUST00000114548.1
ENSMUST00000152459.1
ENSMUST00000143026.1
ENSMUST00000085909.2
ENSMUST00000114547.1
ENSMUST00000034581.3
Cadm1





cell adhesion molecule 1





chr5_+_142629537 0.021 ENSMUST00000036872.9
ENSMUST00000110778.1
Wipi2

WD repeat domain, phosphoinositide interacting 2

chr19_+_23723279 0.017 ENSMUST00000067077.1
Gm9938
predicted gene 9938
chr8_-_46124146 0.016 ENSMUST00000170416.1
Snx25
sorting nexin 25
chr10_-_26373956 0.009 ENSMUST00000105519.3
ENSMUST00000040219.6
L3mbtl3

l(3)mbt-like 3 (Drosophila)

chr18_-_47333311 0.001 ENSMUST00000126684.1
ENSMUST00000156422.1
Sema6a

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 6.0 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.5 3.1 GO:0072318 clathrin coat disassembly(GO:0072318)
0.5 2.5 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.4 1.2 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.3 2.4 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.3 2.2 GO:0061368 maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.3 0.8 GO:0043379 rRNA export from nucleus(GO:0006407) memory T cell differentiation(GO:0043379) response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.2 1.2 GO:0035826 rubidium ion transport(GO:0035826) cellular hypotonic response(GO:0071476)
0.2 1.5 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.2 0.5 GO:0002159 desmosome assembly(GO:0002159)
0.2 1.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 1.3 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.1 0.6 GO:0097167 circadian regulation of translation(GO:0097167)
0.1 2.2 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.4 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.1 0.7 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.8 GO:0031642 negative regulation of myelination(GO:0031642)
0.1 0.4 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.5 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.1 0.3 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.1 0.4 GO:1903898 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.1 1.0 GO:0070842 aggresome assembly(GO:0070842)
0.1 0.5 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 0.2 GO:0009597 detection of virus(GO:0009597)
0.1 0.2 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.0 0.3 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.8 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.5 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.0 1.1 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.4 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.2 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.3 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.0 0.6 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.5 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.2 GO:0070305 response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321)
0.0 0.6 GO:0098780 response to mitochondrial depolarisation(GO:0098780)
0.0 0.6 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.3 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.3 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.0 GO:0009826 unidimensional cell growth(GO:0009826)
0.0 0.3 GO:0030953 astral microtubule organization(GO:0030953)
0.0 1.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.5 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.5 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.6 GO:0050919 negative chemotaxis(GO:0050919)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0031673 H zone(GO:0031673)
0.3 0.8 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.2 8.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 0.5 GO:1990130 Iml1 complex(GO:1990130)
0.1 0.8 GO:0031931 TORC1 complex(GO:0031931)
0.1 0.6 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 0.2 GO:0044753 amphisome(GO:0044753)
0.1 0.2 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.5 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 1.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 6.5 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.8 GO:0005811 lipid particle(GO:0005811)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.4 GO:0097001 ceramide binding(GO:0097001)
0.2 1.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.2 0.7 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2 0.8 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1 0.4 GO:0005118 sevenless binding(GO:0005118)
0.1 6.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 1.2 GO:0071253 connexin binding(GO:0071253)
0.1 0.4 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.3 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 0.5 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 2.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.7 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.2 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.5 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.8 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 1.0 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 1.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 3.1 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.3 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.1 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 0.6 GO:0070888 E-box binding(GO:0070888)
0.0 0.4 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.6 GO:0015485 cholesterol binding(GO:0015485)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.1 1.9 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.1 6.0 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.5 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 1.1 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.5 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.4 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.3 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 1.1 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.4 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 0.6 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.5 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.0 0.6 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 1.5 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.3 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.5 PID_IL6_7_PATHWAY IL6-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 0.8 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 0.8 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.6 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 3.6 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.7 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.5 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.4 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.0 0.6 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.0 0.2 REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.4 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.5 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.0 0.5 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.6 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.2 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.4 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis