Motif ID: Sox4
Z-value: 0.740

Transcription factors associated with Sox4:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Sox4 | ENSMUSG00000076431.4 | Sox4 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Sox4 | mm10_v2_chr13_-_28953690_28953713 | 0.33 | 3.5e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 1.4 | GO:0060244 | negative regulation of cell proliferation involved in contact inhibition(GO:0060244) |
0.4 | 1.3 | GO:0046671 | negative regulation of retinal cell programmed cell death(GO:0046671) |
0.4 | 1.6 | GO:0072137 | condensed mesenchymal cell proliferation(GO:0072137) |
0.4 | 1.6 | GO:2000383 | regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384) |
0.2 | 1.8 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
0.2 | 0.6 | GO:1904049 | negative regulation of spontaneous neurotransmitter secretion(GO:1904049) |
0.2 | 3.0 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
0.1 | 0.7 | GO:0097343 | ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026) |
0.1 | 0.9 | GO:0089700 | protein kinase D signaling(GO:0089700) |
0.1 | 1.2 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
0.1 | 3.5 | GO:0070207 | protein homotrimerization(GO:0070207) |
0.1 | 0.3 | GO:2000620 | positive regulation of histone H4-K16 acetylation(GO:2000620) |
0.1 | 0.9 | GO:0005513 | detection of calcium ion(GO:0005513) |
0.1 | 2.9 | GO:0032967 | positive regulation of collagen biosynthetic process(GO:0032967) |
0.1 | 1.1 | GO:0070574 | cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574) |
0.1 | 2.0 | GO:0022027 | interkinetic nuclear migration(GO:0022027) |
0.1 | 0.3 | GO:0048496 | maintenance of organ identity(GO:0048496) |
0.1 | 1.1 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
0.1 | 0.3 | GO:1904425 | negative regulation of GTP binding(GO:1904425) |
0.1 | 0.4 | GO:1903756 | regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758) |
0.1 | 1.9 | GO:0007614 | short-term memory(GO:0007614) |
0.1 | 1.2 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
0.1 | 0.7 | GO:0050882 | voluntary musculoskeletal movement(GO:0050882) |
0.1 | 0.3 | GO:0097118 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) |
0.1 | 0.3 | GO:0014886 | transition between slow and fast fiber(GO:0014886) |
0.0 | 0.8 | GO:0046697 | decidualization(GO:0046697) |
0.0 | 0.1 | GO:0071544 | diphosphoinositol polyphosphate catabolic process(GO:0071544) |
0.0 | 0.5 | GO:0043653 | mitochondrial fragmentation involved in apoptotic process(GO:0043653) |
0.0 | 0.2 | GO:0010747 | positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) |
0.0 | 2.6 | GO:0042632 | cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092) |
0.0 | 0.3 | GO:0031642 | negative regulation of myelination(GO:0031642) negative regulation of excitatory postsynaptic potential(GO:0090394) negative regulation of receptor catabolic process(GO:2000645) |
0.0 | 0.6 | GO:0070986 | left/right axis specification(GO:0070986) |
0.0 | 0.3 | GO:2000288 | positive regulation of myoblast proliferation(GO:2000288) |
0.0 | 0.2 | GO:1900246 | positive regulation of RIG-I signaling pathway(GO:1900246) |
0.0 | 0.2 | GO:1990845 | adaptive thermogenesis(GO:1990845) |
0.0 | 0.3 | GO:0070307 | lens fiber cell development(GO:0070307) |
0.0 | 0.2 | GO:0035873 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879) |
0.0 | 0.1 | GO:0006451 | selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451) |
0.0 | 0.1 | GO:0018243 | protein O-linked glycosylation via threonine(GO:0018243) |
0.0 | 0.1 | GO:1903351 | response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351) |
0.0 | 2.1 | GO:0007416 | synapse assembly(GO:0007416) |
0.0 | 0.3 | GO:0035855 | megakaryocyte development(GO:0035855) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.0 | 2.9 | GO:0038045 | large latent transforming growth factor-beta complex(GO:0038045) |
0.9 | 3.5 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
0.3 | 1.2 | GO:0044307 | dendritic branch(GO:0044307) |
0.1 | 0.6 | GO:1990761 | growth cone lamellipodium(GO:1990761) |
0.1 | 0.3 | GO:0097543 | ciliary inversin compartment(GO:0097543) |
0.1 | 0.7 | GO:0097542 | ciliary tip(GO:0097542) |
0.0 | 1.6 | GO:0055038 | recycling endosome membrane(GO:0055038) |
0.0 | 4.8 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
0.0 | 2.3 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
0.0 | 0.3 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
0.0 | 0.6 | GO:0097225 | sperm midpiece(GO:0097225) |
0.0 | 0.5 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
0.0 | 1.4 | GO:0005776 | autophagosome(GO:0005776) |
0.0 | 0.1 | GO:0031315 | extrinsic component of mitochondrial outer membrane(GO:0031315) |
0.0 | 0.7 | GO:0060170 | ciliary membrane(GO:0060170) |
0.0 | 0.8 | GO:0005871 | kinesin complex(GO:0005871) |
0.0 | 1.3 | GO:0030496 | midbody(GO:0030496) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 2.9 | GO:0050436 | microfibril binding(GO:0050436) |
0.2 | 0.8 | GO:0004921 | interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970) |
0.2 | 2.6 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
0.1 | 4.8 | GO:0042805 | actinin binding(GO:0042805) |
0.1 | 1.1 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
0.1 | 1.2 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
0.1 | 0.7 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
0.1 | 0.7 | GO:0046790 | virion binding(GO:0046790) |
0.1 | 1.6 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.1 | 0.4 | GO:0047184 | 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) |
0.1 | 0.5 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
0.1 | 0.9 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
0.1 | 0.7 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
0.1 | 1.2 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
0.1 | 0.2 | GO:0017077 | oxidative phosphorylation uncoupler activity(GO:0017077) |
0.0 | 0.3 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
0.0 | 0.3 | GO:0070699 | type II activin receptor binding(GO:0070699) |
0.0 | 3.5 | GO:1990782 | protein tyrosine kinase binding(GO:1990782) |
0.0 | 1.1 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.0 | 0.9 | GO:0004697 | protein kinase C activity(GO:0004697) |
0.0 | 0.3 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.0 | 1.2 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
0.0 | 0.1 | GO:0000298 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) |
0.0 | 0.6 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
0.0 | 0.4 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
0.0 | 0.7 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
0.0 | 0.1 | GO:0035368 | selenocysteine insertion sequence binding(GO:0035368) |
0.0 | 0.2 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 3.5 | PID_IL12_STAT4_PATHWAY | IL12 signaling mediated by STAT4 |
0.1 | 1.6 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
0.0 | 3.9 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
0.0 | 0.7 | PID_NFKAPPAB_CANONICAL_PATHWAY | Canonical NF-kappaB pathway |
0.0 | 1.1 | PID_ERBB1_INTERNALIZATION_PATHWAY | Internalization of ErbB1 |
0.0 | 0.6 | PID_HEDGEHOG_GLI_PATHWAY | Hedgehog signaling events mediated by Gli proteins |
0.0 | 0.5 | PID_ATR_PATHWAY | ATR signaling pathway |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 3.5 | REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |
0.2 | 1.2 | REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS | Genes involved in Tandem pore domain potassium channels |
0.1 | 1.1 | REACTOME_ZINC_TRANSPORTERS | Genes involved in Zinc transporters |
0.0 | 1.2 | REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII | Genes involved in CREB phosphorylation through the activation of CaMKII |
0.0 | 0.9 | REACTOME_CGMP_EFFECTS | Genes involved in cGMP effects |
0.0 | 1.1 | REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
0.0 | 0.4 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PC | Genes involved in Acyl chain remodelling of PC |
0.0 | 0.3 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
0.0 | 0.7 | REACTOME_NOD1_2_SIGNALING_PATHWAY | Genes involved in NOD1/2 Signaling Pathway |
0.0 | 0.3 | REACTOME_NEPHRIN_INTERACTIONS | Genes involved in Nephrin interactions |