Motif ID: Tfap2b

Z-value: 0.785


Transcription factors associated with Tfap2b:

Gene SymbolEntrez IDGene Name
Tfap2b ENSMUSG00000025927.7 Tfap2b

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tfap2bmm10_v2_chr1_+_19212054_19212106-0.603.6e-05Click!


Activity profile for motif Tfap2b.

activity profile for motif Tfap2b


Sorted Z-values histogram for motif Tfap2b

Sorted Z-values for motif Tfap2b



Network of associatons between targets according to the STRING database.



First level regulatory network of Tfap2b

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_158610731 4.991 ENSMUST00000045738.4
Slc32a1
solute carrier family 32 (GABA vesicular transporter), member 1
chr19_+_5740885 4.820 ENSMUST00000081496.5
Ltbp3
latent transforming growth factor beta binding protein 3
chr2_-_36105271 4.308 ENSMUST00000112960.1
ENSMUST00000112967.5
ENSMUST00000112963.1
Lhx6


LIM homeobox protein 6


chr12_+_70825492 4.284 ENSMUST00000057859.7
Frmd6
FERM domain containing 6
chr1_-_56978534 3.713 ENSMUST00000177282.1
Satb2
special AT-rich sequence binding protein 2
chr12_+_84009481 3.518 ENSMUST00000168120.1
Acot1
acyl-CoA thioesterase 1
chr17_+_83215271 3.391 ENSMUST00000170794.1
Pkdcc
protein kinase domain containing, cytoplasmic
chr4_+_48045144 2.903 ENSMUST00000030025.3
Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr5_-_37824580 2.599 ENSMUST00000063116.9
Msx1
msh homeobox 1
chr2_+_59612034 2.536 ENSMUST00000112568.1
ENSMUST00000037526.4
Tanc1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr1_-_56972437 2.459 ENSMUST00000042857.7
Satb2
special AT-rich sequence binding protein 2
chr17_+_86963279 2.446 ENSMUST00000139344.1
Rhoq
ras homolog gene family, member Q
chr2_+_91945703 2.414 ENSMUST00000178895.1
Gm9821
predicted gene 9821
chr7_-_27333602 2.231 ENSMUST00000118583.1
ENSMUST00000118961.1
ENSMUST00000121175.1
Ltbp4


latent transforming growth factor beta binding protein 4


chr3_-_137981523 2.227 ENSMUST00000136613.1
ENSMUST00000029806.6
Dapp1

dual adaptor for phosphotyrosine and 3-phosphoinositides 1

chr13_+_49187485 2.112 ENSMUST00000049022.8
ENSMUST00000120733.1
Ninj1

ninjurin 1

chr1_-_14310198 2.027 ENSMUST00000168081.2
ENSMUST00000027066.6
Eya1

eyes absent 1 homolog (Drosophila)

chr7_+_78578830 1.838 ENSMUST00000064591.4
Gm9885
predicted gene 9885
chr5_-_137314175 1.729 ENSMUST00000024119.9
Trip6
thyroid hormone receptor interactor 6
chr8_+_84723003 1.700 ENSMUST00000098571.4
G430095P16Rik
RIKEN cDNA G430095P16 gene
chr17_+_86963077 1.623 ENSMUST00000024956.8
Rhoq
ras homolog gene family, member Q
chr19_-_6987621 1.597 ENSMUST00000130048.1
ENSMUST00000025914.6
Vegfb

vascular endothelial growth factor B

chr15_-_72034202 1.576 ENSMUST00000159993.1
Col22a1
collagen, type XXII, alpha 1
chr9_-_54647199 1.488 ENSMUST00000128163.1
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr9_-_40455670 1.480 ENSMUST00000165104.1
ENSMUST00000045682.5
Gramd1b

GRAM domain containing 1B

chr12_-_76709997 1.386 ENSMUST00000166101.1
Sptb
spectrin beta, erythrocytic
chr15_-_60824942 1.296 ENSMUST00000100635.3
Fam84b
family with sequence similarity 84, member B
chr4_+_46450892 1.265 ENSMUST00000102926.4
Anp32b
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chrX_+_7722267 1.230 ENSMUST00000125991.1
ENSMUST00000148624.1
Wdr45

WD repeat domain 45

chr2_+_119742306 1.191 ENSMUST00000028758.7
Itpka
inositol 1,4,5-trisphosphate 3-kinase A
chr18_-_60713389 1.172 ENSMUST00000169273.1
Ndst1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr4_+_133176336 1.165 ENSMUST00000105912.1
Wasf2
WAS protein family, member 2
chrX_+_99975570 1.151 ENSMUST00000113779.1
ENSMUST00000113776.1
ENSMUST00000113775.1
ENSMUST00000113780.1
ENSMUST00000113778.1
ENSMUST00000113781.1
ENSMUST00000113783.1
ENSMUST00000071453.2
ENSMUST00000113777.1
Eda








ectodysplasin-A








chr4_-_22488296 1.141 ENSMUST00000178174.1
Pou3f2
POU domain, class 3, transcription factor 2
chr2_-_173276526 1.136 ENSMUST00000036248.6
Pmepa1
prostate transmembrane protein, androgen induced 1
chr18_+_36281069 1.109 ENSMUST00000051301.3
Pura
purine rich element binding protein A
chr2_+_153031852 1.086 ENSMUST00000037235.6
Xkr7
X Kell blood group precursor related family member 7 homolog
chr5_-_121836852 1.083 ENSMUST00000086310.1
Sh2b3
SH2B adaptor protein 3
chr2_+_133552159 1.066 ENSMUST00000028836.6
Bmp2
bone morphogenetic protein 2
chr10_-_58675631 1.060 ENSMUST00000003312.4
Edar
ectodysplasin-A receptor
chr11_+_35121126 1.056 ENSMUST00000069837.3
Slit3
slit homolog 3 (Drosophila)
chrX_+_7723278 1.050 ENSMUST00000144148.1
Wdr45
WD repeat domain 45
chr5_-_121836810 1.035 ENSMUST00000118580.1
ENSMUST00000040308.7
Sh2b3

SH2B adaptor protein 3

chr7_+_27607748 1.026 ENSMUST00000136962.1
Akt2
thymoma viral proto-oncogene 2
chr11_-_59290746 1.017 ENSMUST00000010044.7
Wnt3a
wingless-related MMTV integration site 3A
chr2_-_173276144 1.004 ENSMUST00000139306.1
Pmepa1
prostate transmembrane protein, androgen induced 1
chr9_+_54699548 1.002 ENSMUST00000070070.7
Dnaja4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr7_+_27607997 1.000 ENSMUST00000142365.1
Akt2
thymoma viral proto-oncogene 2
chr5_+_45493374 0.995 ENSMUST00000046122.6
Lap3
leucine aminopeptidase 3
chr15_+_81987835 0.992 ENSMUST00000165777.1
Xrcc6
X-ray repair complementing defective repair in Chinese hamster cells 6
chr2_-_93957040 0.983 ENSMUST00000148314.2
Gm13889
predicted gene 13889
chr11_+_94327984 0.978 ENSMUST00000107818.2
ENSMUST00000051221.6
Ankrd40

ankyrin repeat domain 40

chr14_+_25842146 0.950 ENSMUST00000022416.8
Anxa11
annexin A11
chr7_+_45526330 0.929 ENSMUST00000120985.1
ENSMUST00000051810.8
Plekha4

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4

chr7_-_93081027 0.915 ENSMUST00000098303.1
Gm9934
predicted gene 9934
chr9_+_54699514 0.897 ENSMUST00000154690.1
Dnaja4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr11_-_100414829 0.892 ENSMUST00000066489.6
Leprel4
leprecan-like 4
chr4_-_133967235 0.863 ENSMUST00000123234.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr13_+_37826225 0.818 ENSMUST00000128570.1
Rreb1
ras responsive element binding protein 1
chr3_+_144570409 0.798 ENSMUST00000082437.3
Sep15
selenoprotein
chrX_-_155338460 0.756 ENSMUST00000026328.4
Prdx4
peroxiredoxin 4
chr11_+_94328242 0.743 ENSMUST00000021227.5
Ankrd40
ankyrin repeat domain 40
chr19_-_42752710 0.738 ENSMUST00000076505.3
Pyroxd2
pyridine nucleotide-disulphide oxidoreductase domain 2
chr6_-_39725193 0.733 ENSMUST00000101497.3
Braf
Braf transforming gene
chr7_+_58658181 0.725 ENSMUST00000168747.1
Atp10a
ATPase, class V, type 10A
chr13_+_40917626 0.719 ENSMUST00000067778.6
Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr15_-_102257306 0.717 ENSMUST00000135466.1
Rarg
retinoic acid receptor, gamma
chrX_+_162760427 0.707 ENSMUST00000112326.1
Rbbp7
retinoblastoma binding protein 7
chr1_-_98095596 0.693 ENSMUST00000058762.8
ENSMUST00000097625.3
Pam

peptidylglycine alpha-amidating monooxygenase

chr15_-_99370427 0.690 ENSMUST00000081224.7
ENSMUST00000120633.1
ENSMUST00000088233.6
Fmnl3


formin-like 3


chr6_-_24956106 0.683 ENSMUST00000127247.2
Tmem229a
transmembrane protein 229A
chr12_+_102128718 0.683 ENSMUST00000159329.1
Slc24a4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr3_-_132950043 0.682 ENSMUST00000117164.1
ENSMUST00000093971.4
ENSMUST00000042729.9
ENSMUST00000042744.9
ENSMUST00000117811.1
Npnt




nephronectin




chr15_+_7129557 0.666 ENSMUST00000067190.5
ENSMUST00000164529.1
Lifr

leukemia inhibitory factor receptor

chr14_-_55643251 0.664 ENSMUST00000120041.1
ENSMUST00000121937.1
ENSMUST00000133707.1
ENSMUST00000002391.8
ENSMUST00000121791.1
Tm9sf1




transmembrane 9 superfamily member 1




chr1_-_136234113 0.664 ENSMUST00000120339.1
ENSMUST00000048668.8
5730559C18Rik

RIKEN cDNA 5730559C18 gene

chr8_+_79028317 0.662 ENSMUST00000087927.4
ENSMUST00000098614.2
Zfp827

zinc finger protein 827

chr6_-_37299950 0.652 ENSMUST00000101532.3
Dgki
diacylglycerol kinase, iota
chr19_+_6364557 0.647 ENSMUST00000155973.1
Sf1
splicing factor 1
chr9_+_37613806 0.646 ENSMUST00000002007.3
Siae
sialic acid acetylesterase
chr12_+_102129019 0.638 ENSMUST00000079020.4
Slc24a4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr9_+_61373608 0.633 ENSMUST00000161689.1
Tle3
transducin-like enhancer of split 3, homolog of Drosophila E(spl)
chr14_-_55643523 0.624 ENSMUST00000132338.1
Tm9sf1
transmembrane 9 superfamily member 1
chr17_+_35841491 0.614 ENSMUST00000082337.6
Mdc1
mediator of DNA damage checkpoint 1
chr4_-_133967296 0.605 ENSMUST00000105893.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr2_+_156065180 0.599 ENSMUST00000038860.5
Spag4
sperm associated antigen 4
chr11_-_75178792 0.598 ENSMUST00000071562.2
Ovca2
candidate tumor suppressor in ovarian cancer 2
chr13_+_44731281 0.595 ENSMUST00000174086.1
Jarid2
jumonji, AT rich interactive domain 2
chr2_+_130406478 0.594 ENSMUST00000055421.4
Tmem239
transmembrane 239
chr5_+_30913398 0.593 ENSMUST00000031055.5
Emilin1
elastin microfibril interfacer 1
chr10_-_127211528 0.575 ENSMUST00000013970.7
Pip4k2c
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr4_+_155839724 0.566 ENSMUST00000030947.3
Mxra8
matrix-remodelling associated 8
chr3_+_144570687 0.555 ENSMUST00000106211.1
Sep15
selenoprotein
chrX_+_94724569 0.550 ENSMUST00000101388.2
Zxdb
zinc finger, X-linked, duplicated B
chr14_-_55643720 0.549 ENSMUST00000138085.1
Tm9sf1
transmembrane 9 superfamily member 1
chr10_-_121476248 0.549 ENSMUST00000026902.7
Rassf3
Ras association (RalGDS/AF-6) domain family member 3
chr7_-_63938862 0.546 ENSMUST00000063694.8
Klf13
Kruppel-like factor 13
chr3_-_116424007 0.537 ENSMUST00000090464.4
Cdc14a
CDC14 cell division cycle 14A
chr3_-_116423930 0.533 ENSMUST00000106491.2
Cdc14a
CDC14 cell division cycle 14A
chr7_-_80371197 0.527 ENSMUST00000098346.3
Man2a2
mannosidase 2, alpha 2
chr7_-_66689474 0.516 ENSMUST00000068980.3
Asb7
ankyrin repeat and SOCS box-containing 7
chr15_-_102257449 0.511 ENSMUST00000043172.8
Rarg
retinoic acid receptor, gamma
chr7_-_80232556 0.502 ENSMUST00000071457.5
Cib1
calcium and integrin binding 1 (calmyrin)
chr3_+_68494208 0.487 ENSMUST00000182719.1
Schip1
schwannomin interacting protein 1
chr4_-_133967893 0.486 ENSMUST00000100472.3
ENSMUST00000136327.1
Hmgn2

high mobility group nucleosomal binding domain 2

chr5_-_115158169 0.485 ENSMUST00000053271.5
ENSMUST00000112121.1
Mlec

malectin

chr11_+_5861886 0.484 ENSMUST00000102923.3
Aebp1
AE binding protein 1
chr11_-_70255329 0.475 ENSMUST00000108574.2
ENSMUST00000000329.2
Alox12

arachidonate 12-lipoxygenase

chr9_-_57262591 0.473 ENSMUST00000034846.5
1700017B05Rik
RIKEN cDNA 1700017B05 gene
chr10_-_61452658 0.472 ENSMUST00000167087.1
ENSMUST00000020288.7
Eif4ebp2

eukaryotic translation initiation factor 4E binding protein 2

chrX_+_162760388 0.461 ENSMUST00000033720.5
ENSMUST00000112327.1
Rbbp7

retinoblastoma binding protein 7

chr6_-_97487801 0.459 ENSMUST00000113353.1
ENSMUST00000032146.7
Frmd4b

FERM domain containing 4B

chr2_-_174438996 0.459 ENSMUST00000016400.8
Ctsz
cathepsin Z
chr6_+_88465409 0.456 ENSMUST00000032165.9
Ruvbl1
RuvB-like protein 1
chr7_-_127449109 0.455 ENSMUST00000053392.4
Zfp689
zinc finger protein 689
chr15_-_98871175 0.443 ENSMUST00000178486.2
ENSMUST00000023741.9
Kmt2d

lysine (K)-specific methyltransferase 2D

chr5_+_52582320 0.433 ENSMUST00000177881.1
Gm5866
predicted gene 5866
chr7_-_80232752 0.430 ENSMUST00000065163.8
Cib1
calcium and integrin binding 1 (calmyrin)
chr17_-_70849644 0.423 ENSMUST00000134654.1
ENSMUST00000172229.1
ENSMUST00000127719.1
Tgif1


TGFB-induced factor homeobox 1


chrX_+_73757069 0.417 ENSMUST00000002079.6
Plxnb3
plexin B3
chr12_+_108410625 0.408 ENSMUST00000109857.1
Eml1
echinoderm microtubule associated protein like 1
chr10_-_81349085 0.406 ENSMUST00000141171.1
Hmg20b
high mobility group 20B
chr15_-_36608959 0.402 ENSMUST00000001809.8
Pabpc1
poly(A) binding protein, cytoplasmic 1
chr14_-_55643800 0.401 ENSMUST00000122358.1
Tm9sf1
transmembrane 9 superfamily member 1
chr7_-_139582790 0.389 ENSMUST00000106095.2
Nkx6-2
NK6 homeobox 2
chr3_-_84480419 0.371 ENSMUST00000107689.1
Fhdc1
FH2 domain containing 1
chr19_+_6363896 0.364 ENSMUST00000113487.1
Sf1
splicing factor 1
chr7_-_127448993 0.362 ENSMUST00000106299.1
Zfp689
zinc finger protein 689
chr16_-_38713235 0.360 ENSMUST00000023487.4
Arhgap31
Rho GTPase activating protein 31
chr13_+_12702362 0.359 ENSMUST00000104944.2
Gm2399
predicted gene 2399
chr15_-_11905609 0.358 ENSMUST00000066529.3
Npr3
natriuretic peptide receptor 3
chr11_+_99041237 0.358 ENSMUST00000017637.6
Igfbp4
insulin-like growth factor binding protein 4
chr19_+_6363719 0.356 ENSMUST00000113489.1
ENSMUST00000113488.1
Sf1

splicing factor 1

chr11_+_77348272 0.356 ENSMUST00000181283.1
Ssh2
slingshot homolog 2 (Drosophila)
chr1_-_143702832 0.354 ENSMUST00000018337.7
Cdc73
cell division cycle 73, Paf1/RNA polymerase II complex component
chr7_-_45526146 0.344 ENSMUST00000167273.1
ENSMUST00000042105.8
Ppp1r15a

protein phosphatase 1, regulatory (inhibitor) subunit 15A

chr4_-_141139727 0.344 ENSMUST00000148204.1
ENSMUST00000102487.3
Szrd1

SUZ RNA binding domain containing 1

chr14_-_31830402 0.340 ENSMUST00000014640.7
Ankrd28
ankyrin repeat domain 28
chr11_+_82781108 0.336 ENSMUST00000092849.5
ENSMUST00000021039.5
ENSMUST00000080461.5
ENSMUST00000173347.1
ENSMUST00000173727.1
ENSMUST00000173009.1
ENSMUST00000131537.2
ENSMUST00000173722.1
Lig3







ligase III, DNA, ATP-dependent







chr11_+_102189620 0.332 ENSMUST00000070334.3
ENSMUST00000078975.7
G6pc3

glucose 6 phosphatase, catalytic, 3

chr2_-_164404606 0.330 ENSMUST00000109359.1
ENSMUST00000109358.1
ENSMUST00000103103.3
Matn4


matrilin 4


chr11_-_106920359 0.330 ENSMUST00000167787.1
ENSMUST00000092517.2
Smurf2

SMAD specific E3 ubiquitin protein ligase 2

chr7_-_122067263 0.327 ENSMUST00000033159.3
Ears2
glutamyl-tRNA synthetase 2 (mitochondrial)(putative)
chr2_+_156065738 0.324 ENSMUST00000137966.1
Spag4
sperm associated antigen 4
chr16_-_20425881 0.322 ENSMUST00000077867.3
Abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr8_+_105170668 0.321 ENSMUST00000109395.1
ENSMUST00000109394.1
ENSMUST00000052209.2
ENSMUST00000109392.1
Cbfb



core binding factor beta



chr11_-_58168467 0.320 ENSMUST00000172035.1
ENSMUST00000035604.6
ENSMUST00000102711.2
Gemin5


gem (nuclear organelle) associated protein 5


chr3_-_30969399 0.312 ENSMUST00000177992.1
ENSMUST00000129817.2
ENSMUST00000168645.1
ENSMUST00000108255.1
ENSMUST00000064718.5
ENSMUST00000099163.3
Phc3





polyhomeotic-like 3 (Drosophila)





chr11_-_75454656 0.311 ENSMUST00000173320.1
Wdr81
WD repeat domain 81
chr10_-_117148474 0.306 ENSMUST00000020381.3
Frs2
fibroblast growth factor receptor substrate 2
chr19_-_8819278 0.287 ENSMUST00000088092.5
Ttc9c
tetratricopeptide repeat domain 9C
chr7_+_45705088 0.287 ENSMUST00000080885.3
Dbp
D site albumin promoter binding protein
chr15_-_79834261 0.285 ENSMUST00000148358.1
Cbx6
chromobox 6
chr14_+_61172966 0.283 ENSMUST00000121091.1
Sacs
sacsin
chr17_-_46282991 0.280 ENSMUST00000180283.1
ENSMUST00000012440.6
ENSMUST00000164342.2
Tjap1


tight junction associated protein 1


chr18_+_60774510 0.280 ENSMUST00000025511.3
Rps14
ribosomal protein S14
chr19_-_3282958 0.277 ENSMUST00000119292.1
ENSMUST00000025751.3
Ighmbp2

immunoglobulin mu binding protein 2

chr7_+_45705518 0.274 ENSMUST00000107740.1
ENSMUST00000107741.1
Dbp

D site albumin promoter binding protein

chr18_+_64340225 0.273 ENSMUST00000175965.2
ENSMUST00000115145.3
Onecut2

one cut domain, family member 2

chr2_+_155956537 0.271 ENSMUST00000109619.2
ENSMUST00000039994.7
ENSMUST00000094421.4
ENSMUST00000151569.1
ENSMUST00000109618.1
Cep250




centrosomal protein 250




chr14_+_79451791 0.270 ENSMUST00000100359.1
Zbtbd6
kelch repeat and BTB (POZ) domain containing 6
chr6_-_124712131 0.269 ENSMUST00000004379.5
Emg1
EMG1 nucleolar protein homolog (S. cerevisiae)
chr16_+_24448082 0.268 ENSMUST00000078988.2
Lpp
LIM domain containing preferred translocation partner in lipoma
chr14_+_70554056 0.265 ENSMUST00000022691.7
Hr
hairless
chr16_+_23609895 0.261 ENSMUST00000038423.5
Rtp4
receptor transporter protein 4
chr7_+_25282179 0.245 ENSMUST00000163320.1
ENSMUST00000005578.6
Cic

capicua homolog (Drosophila)

chr17_-_32284715 0.236 ENSMUST00000127893.1
Brd4
bromodomain containing 4
chr1_-_135105210 0.226 ENSMUST00000044828.7
Lgr6
leucine-rich repeat-containing G protein-coupled receptor 6
chr8_+_105297663 0.220 ENSMUST00000015003.8
E2f4
E2F transcription factor 4
chr1_+_34160253 0.211 ENSMUST00000183302.1
Dst
dystonin
chr2_+_25262589 0.203 ENSMUST00000114336.3
Tprn
taperin
chr18_+_60774675 0.197 ENSMUST00000118551.1
Rps14
ribosomal protein S14
chr17_-_83631892 0.195 ENSMUST00000051482.1
Kcng3
potassium voltage-gated channel, subfamily G, member 3
chr17_-_34031644 0.191 ENSMUST00000171872.1
Slc39a7
solute carrier family 39 (zinc transporter), member 7
chr13_-_9764865 0.189 ENSMUST00000128658.1
Zmynd11
zinc finger, MYND domain containing 11
chr11_-_96977660 0.181 ENSMUST00000107626.1
ENSMUST00000107624.1
Sp2

Sp2 transcription factor

chr16_+_20629799 0.180 ENSMUST00000003898.5
Ece2
endothelin converting enzyme 2
chr14_+_21499770 0.173 ENSMUST00000182855.1
ENSMUST00000069648.7
ENSMUST00000182405.1
Kat6b


K(lysine) acetyltransferase 6B


chr4_+_127126034 0.171 ENSMUST00000094712.4
Gm12942
predicted gene 12942
chr13_-_54468805 0.170 ENSMUST00000026990.5
Thoc3
THO complex 3
chr11_-_3774706 0.168 ENSMUST00000155197.1
Osbp2
oxysterol binding protein 2
chr6_+_8209216 0.161 ENSMUST00000040017.7
Mios
missing oocyte, meiosis regulator, homolog (Drosophila)
chr7_+_28180226 0.160 ENSMUST00000172467.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr7_+_89404356 0.159 ENSMUST00000058755.3
Fzd4
frizzled homolog 4 (Drosophila)
chr13_+_54949388 0.158 ENSMUST00000026994.7
ENSMUST00000109994.2
Unc5a

unc-5 homolog A (C. elegans)

chr17_-_35700520 0.158 ENSMUST00000119825.1
Ddr1
discoidin domain receptor family, member 1
chr17_-_46890405 0.155 ENSMUST00000086675.3
A330017A19Rik
RIKEN cDNA A330017A19 gene
chr19_+_42090422 0.154 ENSMUST00000066778.4
Pi4k2a
phosphatidylinositol 4-kinase type 2 alpha
chr10_+_13966268 0.152 ENSMUST00000015645.4
Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr16_+_20629842 0.151 ENSMUST00000122306.1
ENSMUST00000133344.1
Ece2

endothelin converting enzyme 2

chr7_+_28180272 0.151 ENSMUST00000173223.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr2_-_181693810 0.141 ENSMUST00000108776.1
ENSMUST00000108771.1
ENSMUST00000108779.1
ENSMUST00000108769.1
ENSMUST00000108772.1
ENSMUST00000002532.2
Rgs19





regulator of G-protein signaling 19





chr16_+_58670208 0.130 ENSMUST00000060077.5
Cpox
coproporphyrinogen oxidase
chr9_+_62342449 0.129 ENSMUST00000156461.1
Anp32a
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr8_-_111910171 0.127 ENSMUST00000034430.4
Chst5
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
chr2_+_28513105 0.120 ENSMUST00000135803.1
Ralgds
ral guanine nucleotide dissociation stimulator
chr19_+_27217011 0.118 ENSMUST00000164746.1
ENSMUST00000172302.1
Vldlr

very low density lipoprotein receptor

chr12_+_108410542 0.117 ENSMUST00000054955.7
Eml1
echinoderm microtubule associated protein like 1
chr4_-_133967953 0.116 ENSMUST00000102553.4
Hmgn2
high mobility group nucleosomal binding domain 2
chr6_+_124712279 0.103 ENSMUST00000004375.9
Phb2
prohibitin 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:1902460 transforming growth factor beta activation(GO:0036363) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
1.1 1.1 GO:0003134 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134)
1.0 1.0 GO:0042660 positive regulation of cell fate specification(GO:0042660)
1.0 2.9 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
0.9 2.6 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.7 4.3 GO:0003383 apical constriction(GO:0003383)
0.6 3.9 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.6 3.4 GO:0090005 negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.6 5.0 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.4 2.1 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.4 6.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.4 1.6 GO:0035470 positive regulation of vascular wound healing(GO:0035470)
0.4 1.2 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.3 2.0 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.3 2.0 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.3 1.2 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.3 1.7 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.2 1.0 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.2 0.9 GO:2000256 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163) positive regulation of male germ cell proliferation(GO:2000256)
0.2 0.7 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.2 0.4 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.2 1.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.2 0.4 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.2 1.1 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.2 1.9 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.2 2.3 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.2 0.8 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 4.0 GO:1903077 negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.1 0.6 GO:0060857 establishment of glial blood-brain barrier(GO:0060857)
0.1 1.1 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1 3.3 GO:0097062 dendritic spine maintenance(GO:0097062)
0.1 0.7 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.5 GO:0019372 lipoxygenase pathway(GO:0019372)
0.1 0.3 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 0.5 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.1 0.5 GO:0010755 regulation of plasminogen activation(GO:0010755)
0.1 1.4 GO:0030238 male sex determination(GO:0030238)
0.1 0.7 GO:0010694 positive regulation of alkaline phosphatase activity(GO:0010694)
0.1 1.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.3 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 1.3 GO:0097186 amelogenesis(GO:0097186)
0.1 1.1 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 1.8 GO:0060033 anatomical structure regression(GO:0060033)
0.1 2.1 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.1 0.9 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1 0.7 GO:2000301 myeloid progenitor cell differentiation(GO:0002318) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 0.8 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.1 1.1 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 0.3 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 5.7 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.1 0.3 GO:0090298 negative regulation of mitochondrial DNA replication(GO:0090298)
0.1 0.4 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.3 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.1 0.2 GO:1990523 bone regeneration(GO:1990523)
0.1 0.7 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.1 0.4 GO:0002158 osteoclast proliferation(GO:0002158)
0.1 0.5 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.1 0.3 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.1 0.3 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.1 0.7 GO:0046959 habituation(GO:0046959)
0.1 0.5 GO:0006013 mannose metabolic process(GO:0006013)
0.1 0.2 GO:0061300 extracellular matrix-cell signaling(GO:0035426) cerebellum vasculature development(GO:0061300)
0.1 1.0 GO:0032506 cytokinetic process(GO:0032506)
0.1 0.2 GO:0045575 basophil activation involved in immune response(GO:0002276) basophil activation(GO:0045575)
0.1 1.2 GO:1902745 positive regulation of lamellipodium assembly(GO:0010592) megakaryocyte development(GO:0035855) positive regulation of lamellipodium organization(GO:1902745)
0.0 1.7 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.3 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.4 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.9 GO:0043486 histone exchange(GO:0043486)
0.0 0.4 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 1.5 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.0 0.1 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.4 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.1 GO:0060744 negative regulation of mammary gland epithelial cell proliferation(GO:0033600) thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.2 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.5 GO:0001553 luteinization(GO:0001553)
0.0 0.3 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.5 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.4 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.4 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.4 GO:0033523 endodermal cell fate commitment(GO:0001711) histone H2B ubiquitination(GO:0033523)
0.0 0.3 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 1.2 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.6 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.3 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.2 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.2 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 1.8 GO:0007179 transforming growth factor beta receptor signaling pathway(GO:0007179)
0.0 0.2 GO:0008090 retrograde axonal transport(GO:0008090)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.6 GO:0044316 cone cell pedicle(GO:0044316)
0.3 1.0 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.2 1.0 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.2 0.9 GO:0008091 spectrin(GO:0008091)
0.1 0.7 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 2.0 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 2.0 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.4 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.1 1.0 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1 1.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.5 GO:0097255 R2TP complex(GO:0097255)
0.1 6.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 0.9 GO:0032433 filopodium tip(GO:0032433)
0.1 0.2 GO:0031673 H zone(GO:0031673)
0.1 0.7 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.5 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 2.3 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.9 GO:0005581 collagen trimer(GO:0005581)
0.0 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.4 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 0.3 GO:0032797 SMN complex(GO:0032797)
0.0 0.6 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 4.6 GO:0043296 apical junction complex(GO:0043296)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 3.0 GO:0005884 actin filament(GO:0005884)
0.0 8.0 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 5.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.5 GO:0099738 cell cortex region(GO:0099738)
0.0 0.5 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.3 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.7 GO:0030667 secretory granule membrane(GO:0030667)
0.0 1.4 GO:0032993 protein-DNA complex(GO:0032993)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.5 1.6 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.3 1.4 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.3 1.0 GO:0005110 frizzled-2 binding(GO:0005110)
0.3 1.2 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.3 3.6 GO:0005522 profilin binding(GO:0005522)
0.3 1.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.3 6.7 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.3 1.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.2 0.7 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.2 0.7 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.2 0.7 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924)
0.2 3.5 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.2 0.9 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.2 1.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.2 1.1 GO:0019211 phosphatase activator activity(GO:0019211)
0.1 1.5 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 2.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 1.7 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 1.1 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.7 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.4 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.7 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 1.0 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.6 GO:0098634 protein binding involved in cell-matrix adhesion(GO:0098634)
0.1 1.0 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 2.9 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.9 GO:0043495 protein anchor(GO:0043495)
0.1 0.2 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.1 0.4 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 5.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.3 GO:0030621 U4 snRNA binding(GO:0030621)
0.1 1.2 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 2.1 GO:0050699 WW domain binding(GO:0050699)
0.1 1.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.3 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 0.2 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.1 0.4 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.5 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 1.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.5 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.4 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.5 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.8 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.5 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 1.1 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.9 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 2.1 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 1.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.4 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.7 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.3 GO:0050308 carbohydrate phosphatase activity(GO:0019203) sugar-phosphatase activity(GO:0050308)
0.0 2.0 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 2.3 GO:0002039 p53 binding(GO:0002039)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.5 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.5 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.9 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.3 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.4 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.5 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 0.4 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.9 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.4 GO:0003727 single-stranded RNA binding(GO:0003727)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.2 6.1 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.1 1.6 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.1 4.7 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.1 10.6 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 2.1 PID_EPO_PATHWAY EPO signaling pathway
0.0 1.2 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 1.0 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.6 NABA_COLLAGENS Genes encoding collagen proteins
0.0 1.7 PID_BMP_PATHWAY BMP receptor signaling
0.0 1.2 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.4 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.2 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 2.0 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.2 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.6 PID_ATM_PATHWAY ATM pathway
0.0 0.5 PID_MYC_PATHWAY C-MYC pathway
0.0 1.1 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.2 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.0 0.3 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.0 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 2.0 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.6 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 2.8 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 0.7 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 4.1 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.1 REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 1.6 REACTOME_DOUBLE_STRAND_BREAK_REPAIR Genes involved in Double-Strand Break Repair
0.1 1.3 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.5 REACTOME_N_GLYCAN_TRIMMING_IN_THE_ER_AND_CALNEXIN_CALRETICULIN_CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 1.2 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.6 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.7 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 0.9 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.3 REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 1.6 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 1.2 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 4.0 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.4 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.6 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.3 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.7 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.6 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.3 REACTOME_NEGATIVE_REGULATION_OF_FGFR_SIGNALING Genes involved in Negative regulation of FGFR signaling
0.0 0.3 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.3 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.0 0.9 REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.0 0.5 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.2 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.2 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters