Motif ID: Cbfb

Z-value: 0.449


Transcription factors associated with Cbfb:

Gene SymbolEntrez IDGene Name
Cbfb ENSMUSG00000031885.7 Cbfb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cbfbmm10_v2_chr8_+_105170668_1051706860.153.4e-01Click!


Activity profile for motif Cbfb.

activity profile for motif Cbfb


Sorted Z-values histogram for motif Cbfb

Sorted Z-values for motif Cbfb



Network of associatons between targets according to the STRING database.



First level regulatory network of Cbfb

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_66801577 2.623 ENSMUST00000168589.1
Sla
src-like adaptor
chr8_+_27260327 2.108 ENSMUST00000033880.5
Eif4ebp1
eukaryotic translation initiation factor 4E binding protein 1
chr19_-_50678642 1.628 ENSMUST00000072685.6
ENSMUST00000164039.2
Sorcs1

VPS10 domain receptor protein SORCS 1

chr19_-_50678485 1.223 ENSMUST00000111756.3
Sorcs1
VPS10 domain receptor protein SORCS 1
chr14_-_101729690 1.093 ENSMUST00000066461.3
Gm9922
predicted gene 9922
chr14_+_101729907 1.079 ENSMUST00000100337.3
Lmo7
LIM domain only 7
chr12_+_95692212 0.875 ENSMUST00000057324.3
Flrt2
fibronectin leucine rich transmembrane protein 2
chr9_-_48480540 0.703 ENSMUST00000034524.3
Rexo2
REX2, RNA exonuclease 2 homolog (S. cerevisiae)
chr2_+_72297895 0.585 ENSMUST00000144111.1
Zak
sterile alpha motif and leucine zipper containing kinase AZK
chr4_-_6990774 0.581 ENSMUST00000039987.3
Tox
thymocyte selection-associated high mobility group box
chr2_+_35132194 0.446 ENSMUST00000113034.1
ENSMUST00000113037.3
ENSMUST00000113033.2
Cep110


centrosomal protein 110


chr2_+_164948219 0.399 ENSMUST00000017881.2
Mmp9
matrix metallopeptidase 9
chr7_-_115824699 0.297 ENSMUST00000169129.1
Sox6
SRY-box containing gene 6
chr4_+_108847827 0.217 ENSMUST00000102738.2
Kti12
KTI12 homolog, chromatin associated (S. cerevisiae)
chr15_+_99393219 0.150 ENSMUST00000159209.1
Tmbim6
transmembrane BAX inhibitor motif containing 6
chr3_+_121291725 0.121 ENSMUST00000039442.7
Alg14
asparagine-linked glycosylation 14
chr19_+_6061176 0.117 ENSMUST00000162726.3
Znhit2
zinc finger, HIT domain containing 2
chr2_+_172393794 0.101 ENSMUST00000099061.2
ENSMUST00000103073.2
Cass4

Cas scaffolding protein family member 4

chr2_+_32721055 0.087 ENSMUST00000074248.4
Sh2d3c
SH2 domain containing 3C
chr15_+_99393610 0.063 ENSMUST00000159531.1
Tmbim6
transmembrane BAX inhibitor motif containing 6
chr4_+_10874498 0.055 ENSMUST00000080517.7
ENSMUST00000101504.2
2610301B20Rik

RIKEN cDNA 2610301B20 gene

chr7_-_46795881 0.049 ENSMUST00000107653.1
ENSMUST00000107654.1
ENSMUST00000014562.7
ENSMUST00000152759.1
Hps5



Hermansky-Pudlak syndrome 5 homolog (human)



chr15_+_99393574 0.047 ENSMUST00000162624.1
Tmbim6
transmembrane BAX inhibitor motif containing 6
chr15_+_99392948 0.042 ENSMUST00000161250.1
ENSMUST00000160635.1
ENSMUST00000161778.1
Tmbim6


transmembrane BAX inhibitor motif containing 6


chr4_-_117891994 0.041 ENSMUST00000030265.3
Dph2
DPH2 homolog (S. cerevisiae)
chrX_+_99136119 0.037 ENSMUST00000052839.6
Efnb1
ephrin B1
chr7_-_90129339 0.036 ENSMUST00000181189.1
2310010J17Rik
RIKEN cDNA 2310010J17 gene
chr8_+_3353415 0.028 ENSMUST00000098966.3
A430078G23Rik
RIKEN cDNA A430078G23 gene
chr17_-_64331817 0.027 ENSMUST00000172733.1
ENSMUST00000172818.1
Pja2

praja 2, RING-H2 motif containing

chr1_-_16656843 0.026 ENSMUST00000115352.3
Tceb1
transcription elongation factor B (SIII), polypeptide 1
chr5_+_24364804 0.016 ENSMUST00000030834.4
ENSMUST00000115090.1
Nos3

nitric oxide synthase 3, endothelial cell


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 0.9 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 0.4 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.1 0.3 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 2.6 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.3 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.1 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.0 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 2.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 0.9 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.3 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 1.1 GO:0042805 actinin binding(GO:0042805)
0.0 0.7 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.4 GO:0001968 fibronectin binding(GO:0001968)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.1 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.6 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.4 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 2.6 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.4 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix