Motif ID: Ascl2

Z-value: 0.667


Transcription factors associated with Ascl2:

Gene SymbolEntrez IDGene Name
Ascl2 ENSMUSG00000009248.5 Ascl2



Activity profile for motif Ascl2.

activity profile for motif Ascl2


Sorted Z-values histogram for motif Ascl2

Sorted Z-values for motif Ascl2



Network of associatons between targets according to the STRING database.



First level regulatory network of Ascl2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_106458440 3.767 ENSMUST00000086795.6
Barhl2
BarH-like 2 (Drosophila)
chr8_+_31091593 3.020 ENSMUST00000161713.1
Dusp26
dual specificity phosphatase 26 (putative)
chr7_-_28302238 2.722 ENSMUST00000108315.3
Dll3
delta-like 3 (Drosophila)
chr11_+_99864476 2.067 ENSMUST00000092694.3
Gm11559
predicted gene 11559
chr12_-_40037387 1.922 ENSMUST00000146905.1
Arl4a
ADP-ribosylation factor-like 4A
chr3_+_123446913 1.893 ENSMUST00000029603.8
Prss12
protease, serine, 12 neurotrypsin (motopsin)
chr1_-_84696182 1.800 ENSMUST00000049126.6
Dner
delta/notch-like EGF-related receptor
chr8_+_105518736 1.724 ENSMUST00000034363.5
Hsd11b2
hydroxysteroid 11-beta dehydrogenase 2
chr12_-_40038025 1.644 ENSMUST00000101472.3
Arl4a
ADP-ribosylation factor-like 4A
chr6_+_56017489 1.621 ENSMUST00000052827.4
Ppp1r17
protein phosphatase 1, regulatory subunit 17
chr3_-_116253467 1.618 ENSMUST00000090473.5
Gpr88
G-protein coupled receptor 88
chr6_+_105677745 1.565 ENSMUST00000113261.2
ENSMUST00000113264.2
Cntn4

contactin 4

chr3_-_17786834 1.519 ENSMUST00000099198.2
Gm10742
predicted gene 10742
chr2_+_136052180 1.518 ENSMUST00000144403.1
Lamp5
lysosomal-associated membrane protein family, member 5
chr7_-_141443314 1.432 ENSMUST00000106005.2
Lrdd
leucine-rich and death domain containing
chr7_+_142471838 1.415 ENSMUST00000038946.2
Lsp1
lymphocyte specific 1
chr8_-_105471481 1.364 ENSMUST00000014990.6
Tppp3
tubulin polymerization-promoting protein family member 3
chr7_+_16875302 1.331 ENSMUST00000108493.1
Dact3
dapper homolog 3, antagonist of beta-catenin (xenopus)
chr13_-_98206151 1.318 ENSMUST00000109426.1
Arhgef28
Rho guanine nucleotide exchange factor (GEF) 28
chr5_-_69341699 1.300 ENSMUST00000054095.4
Kctd8
potassium channel tetramerisation domain containing 8
chr13_-_117025505 1.277 ENSMUST00000022239.6
Parp8
poly (ADP-ribose) polymerase family, member 8
chr12_-_17176888 1.260 ENSMUST00000170580.1
Kcnf1
potassium voltage-gated channel, subfamily F, member 1
chr9_+_74848437 1.247 ENSMUST00000161862.1
ENSMUST00000162089.1
ENSMUST00000160017.1
ENSMUST00000160950.1
Gm16551


Gm20649
predicted gene 16551


predicted gene 20649
chr10_+_78780470 1.244 ENSMUST00000005490.8
Slc1a6
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
chrX_-_133688978 1.234 ENSMUST00000149154.1
ENSMUST00000167944.1
Pcdh19

protocadherin 19

chr6_-_56362356 1.219 ENSMUST00000044505.7
ENSMUST00000166102.1
ENSMUST00000164037.1
ENSMUST00000114327.2
Pde1c



phosphodiesterase 1C



chr7_+_100227638 1.189 ENSMUST00000054436.8
Pgm2l1
phosphoglucomutase 2-like 1
chr3_-_33143227 1.185 ENSMUST00000108219.1
Pex5l
peroxisomal biogenesis factor 5-like
chr7_+_142472080 1.172 ENSMUST00000105966.1
Lsp1
lymphocyte specific 1
chr9_-_57836706 1.155 ENSMUST00000164010.1
ENSMUST00000171444.1
ENSMUST00000098686.3
Arid3b


AT rich interactive domain 3B (BRIGHT-like)


chr13_+_24638636 1.143 ENSMUST00000110384.2
ENSMUST00000058009.9
ENSMUST00000038477.6
Fam65b


family with sequence similarity 65, member B


chrX_+_143518576 1.123 ENSMUST00000033640.7
Pak3
p21 protein (Cdc42/Rac)-activated kinase 3
chr12_+_116485714 1.116 ENSMUST00000070733.7
Ptprn2
protein tyrosine phosphatase, receptor type, N polypeptide 2
chr9_-_58201705 1.102 ENSMUST00000163200.1
ENSMUST00000165276.1
Islr2

immunoglobulin superfamily containing leucine-rich repeat 2

chr5_+_114568016 1.080 ENSMUST00000043650.7
Fam222a
family with sequence similarity 222, member A
chr2_-_170406501 1.075 ENSMUST00000154650.1
Bcas1
breast carcinoma amplified sequence 1
chr9_+_57998036 1.067 ENSMUST00000181289.1
Gm17322
predicted gene, 17322
chr10_+_94514825 1.060 ENSMUST00000065060.5
Tmcc3
transmembrane and coiled coil domains 3
chrX_-_106485214 1.060 ENSMUST00000039447.7
Fndc3c1
fibronectin type III domain containing 3C1
chr6_-_72235559 1.054 ENSMUST00000042646.7
Atoh8
atonal homolog 8 (Drosophila)
chr10_+_80494835 1.054 ENSMUST00000051773.8
Onecut3
one cut domain, family member 3
chr19_+_5068077 1.053 ENSMUST00000070630.6
Cd248
CD248 antigen, endosialin
chr6_+_14901344 1.052 ENSMUST00000115477.1
Foxp2
forkhead box P2
chr8_-_122699066 1.045 ENSMUST00000127984.1
Cbfa2t3
core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
chr15_+_4375462 1.015 ENSMUST00000061925.4
Plcxd3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr6_-_50261743 1.012 ENSMUST00000101405.3
ENSMUST00000165099.1
ENSMUST00000170142.1
Dfna5


deafness, autosomal dominant 5 (human)


chr4_-_35845204 1.010 ENSMUST00000164772.1
ENSMUST00000065173.2
Lingo2

leucine rich repeat and Ig domain containing 2

chr6_-_12749193 1.005 ENSMUST00000046121.6
ENSMUST00000172356.1
Thsd7a

thrombospondin, type I, domain containing 7A

chr19_-_16873830 1.000 ENSMUST00000072915.2
Foxb2
forkhead box B2
chr2_-_172940299 0.992 ENSMUST00000009143.7
Bmp7
bone morphogenetic protein 7
chrX_-_122397351 0.988 ENSMUST00000079490.4
Nap1l3
nucleosome assembly protein 1-like 3
chr5_+_149411749 0.966 ENSMUST00000093110.5
Medag
mesenteric estrogen dependent adipogenesis
chr11_-_68927049 0.949 ENSMUST00000038932.7
Odf4
outer dense fiber of sperm tails 4
chrX_+_109095359 0.941 ENSMUST00000033598.8
Sh3bgrl
SH3-binding domain glutamic acid-rich protein like
chr12_+_79130777 0.902 ENSMUST00000021550.6
Arg2
arginase type II
chr12_+_17690793 0.894 ENSMUST00000071858.3
Hpcal1
hippocalcin-like 1
chr6_+_4755327 0.883 ENSMUST00000176551.1
Peg10
paternally expressed 10
chr2_+_35282380 0.879 ENSMUST00000028239.6
Gsn
gelsolin
chr1_+_72824482 0.872 ENSMUST00000047328.4
Igfbp2
insulin-like growth factor binding protein 2
chr1_+_129273344 0.864 ENSMUST00000073527.6
ENSMUST00000040311.7
Thsd7b

thrombospondin, type I, domain containing 7B

chr1_+_74854954 0.862 ENSMUST00000160379.2
Cdk5r2
cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chr1_-_164458345 0.861 ENSMUST00000027863.7
Atp1b1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr7_-_119184374 0.860 ENSMUST00000084650.4
Gpr139
G protein-coupled receptor 139
chr10_-_92162753 0.857 ENSMUST00000182197.1
Rmst
rhabdomyosarcoma 2 associated transcript (non-coding RNA)
chr4_+_43957678 0.848 ENSMUST00000107855.1
Glipr2
GLI pathogenesis-related 2
chr5_-_66618772 0.845 ENSMUST00000162994.1
ENSMUST00000159512.1
ENSMUST00000159786.1
Apbb2


amyloid beta (A4) precursor protein-binding, family B, member 2


chr15_-_102004305 0.828 ENSMUST00000023952.8
Krt8
keratin 8
chr16_+_72663143 0.828 ENSMUST00000023600.7
Robo1
roundabout homolog 1 (Drosophila)
chr9_-_22052021 0.825 ENSMUST00000003501.7
Elavl3
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)
chr9_-_96437434 0.823 ENSMUST00000070500.2
BC043934
cDNA sequence BC043934
chr6_-_77979515 0.821 ENSMUST00000159626.1
ENSMUST00000075340.5
ENSMUST00000162273.1
Ctnna2


catenin (cadherin associated protein), alpha 2


chr15_-_78773452 0.802 ENSMUST00000018313.5
Mfng
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chrX_+_134404780 0.785 ENSMUST00000113224.2
ENSMUST00000113226.1
Drp2

dystrophin related protein 2

chr1_+_153665274 0.785 ENSMUST00000152114.1
ENSMUST00000111812.1
Rgs8

regulator of G-protein signaling 8

chrX_+_114474312 0.781 ENSMUST00000113371.1
ENSMUST00000040504.5
Klhl4

kelch-like 4

chr4_+_43957401 0.778 ENSMUST00000030202.7
Glipr2
GLI pathogenesis-related 2
chr10_+_69212634 0.777 ENSMUST00000020101.5
Rhobtb1
Rho-related BTB domain containing 1
chr19_+_45560569 0.775 ENSMUST00000047057.7
Dpcd
deleted in primary ciliary dyskinesia
chr5_+_81021202 0.770 ENSMUST00000117253.1
ENSMUST00000120128.1
Lphn3

latrophilin 3

chrX_-_106485367 0.768 ENSMUST00000140707.1
Fndc3c1
fibronectin type III domain containing 3C1
chr8_+_62951195 0.768 ENSMUST00000118003.1
Spock3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3
chr11_+_97450136 0.766 ENSMUST00000107601.1
Arhgap23
Rho GTPase activating protein 23
chr7_+_16944645 0.764 ENSMUST00000094807.5
Pnmal2
PNMA-like 2
chr7_+_142460834 0.730 ENSMUST00000018963.4
ENSMUST00000105967.1
Lsp1

lymphocyte specific 1

chr15_-_63997969 0.723 ENSMUST00000164532.1
Fam49b
family with sequence similarity 49, member B
chr17_-_35027909 0.717 ENSMUST00000040151.2
Sapcd1
suppressor APC domain containing 1
chr11_-_79146407 0.707 ENSMUST00000018478.4
ENSMUST00000108264.1
Ksr1

kinase suppressor of ras 1

chr6_-_77979652 0.696 ENSMUST00000161846.1
ENSMUST00000160894.1
Ctnna2

catenin (cadherin associated protein), alpha 2

chr4_+_11156411 0.683 ENSMUST00000029865.3
Trp53inp1
transformation related protein 53 inducible nuclear protein 1
chr7_+_142460809 0.674 ENSMUST00000105968.1
Lsp1
lymphocyte specific 1
chrX_-_16911774 0.671 ENSMUST00000040134.7
Ndp
Norrie disease (pseudoglioma) (human)
chr8_+_70863127 0.663 ENSMUST00000050921.2
A230052G05Rik
RIKEN cDNA A230052G05 gene
chr2_-_17731035 0.660 ENSMUST00000028080.5
Nebl
nebulette
chr8_-_47990535 0.660 ENSMUST00000057561.7
Wwc2
WW, C2 and coiled-coil domain containing 2
chr7_+_99267428 0.659 ENSMUST00000068973.4
ENSMUST00000122101.1
Map6

microtubule-associated protein 6

chr8_-_125898291 0.653 ENSMUST00000047239.6
Pcnxl2
pecanex-like 2 (Drosophila)
chr14_+_57999305 0.650 ENSMUST00000180534.1
3110083C13Rik
RIKEN cDNA 3110083C13 gene
chr2_+_34772089 0.648 ENSMUST00000028222.6
ENSMUST00000100171.2
Hspa5

heat shock protein 5

chr11_-_79059872 0.629 ENSMUST00000141409.1
Ksr1
kinase suppressor of ras 1
chr2_+_167538192 0.622 ENSMUST00000052631.7
Snai1
snail homolog 1 (Drosophila)
chr11_-_46312220 0.620 ENSMUST00000129474.1
ENSMUST00000093166.4
ENSMUST00000165599.2
Cyfip2


cytoplasmic FMR1 interacting protein 2


chr9_-_39604124 0.605 ENSMUST00000042485.4
ENSMUST00000141370.1
AW551984

expressed sequence AW551984

chr6_-_92534855 0.603 ENSMUST00000113446.1
Prickle2
prickle homolog 2 (Drosophila)
chr4_-_133263042 0.601 ENSMUST00000105908.3
ENSMUST00000030674.7
Sytl1

synaptotagmin-like 1

chrX_-_36989656 0.601 ENSMUST00000060474.7
ENSMUST00000053456.4
ENSMUST00000115239.3
Sept6


septin 6


chr1_-_88205674 0.591 ENSMUST00000119972.2
Dnajb3
DnaJ (Hsp40) homolog, subfamily B, member 3
chr13_-_107890059 0.588 ENSMUST00000105097.2
Zswim6
zinc finger SWIM-type containing 6
chr5_-_66618636 0.583 ENSMUST00000162382.1
ENSMUST00000160870.1
ENSMUST00000087256.5
ENSMUST00000160103.1
ENSMUST00000162349.1
Apbb2




amyloid beta (A4) precursor protein-binding, family B, member 2




chr4_+_33031371 0.583 ENSMUST00000124992.1
Ube2j1
ubiquitin-conjugating enzyme E2J 1
chr3_+_136670076 0.579 ENSMUST00000070198.7
Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr13_-_98891036 0.575 ENSMUST00000109399.2
Tnpo1
transportin 1
chrX_-_13846508 0.566 ENSMUST00000115436.2
ENSMUST00000033321.4
ENSMUST00000115438.3
Cask


calcium/calmodulin-dependent serine protein kinase (MAGUK family)


chr9_-_43239816 0.563 ENSMUST00000034512.5
Oaf
OAF homolog (Drosophila)
chr11_+_98446826 0.562 ENSMUST00000019456.4
Grb7
growth factor receptor bound protein 7
chr10_+_123264076 0.561 ENSMUST00000050756.7
Fam19a2
family with sequence similarity 19, member A2
chr7_+_126950837 0.559 ENSMUST00000106332.1
Sez6l2
seizure related 6 homolog like 2
chr6_-_29179584 0.559 ENSMUST00000159200.1
Prrt4
proline-rich transmembrane protein 4
chr8_+_105276438 0.547 ENSMUST00000014920.6
Nol3
nucleolar protein 3 (apoptosis repressor with CARD domain)
chr7_+_123982799 0.546 ENSMUST00000106437.1
Hs3st4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr1_-_183147461 0.542 ENSMUST00000171366.1
Disp1
dispatched homolog 1 (Drosophila)
chr2_+_125136692 0.538 ENSMUST00000099452.2
Ctxn2
cortexin 2
chr1_+_153665627 0.534 ENSMUST00000147482.1
Rgs8
regulator of G-protein signaling 8
chr1_+_153665587 0.533 ENSMUST00000147700.1
Rgs8
regulator of G-protein signaling 8
chr4_-_43523595 0.532 ENSMUST00000107914.3
Tpm2
tropomyosin 2, beta
chr7_-_92637079 0.530 ENSMUST00000056106.7
ENSMUST00000118157.1
Ankrd42

ankyrin repeat domain 42

chr7_-_16924114 0.525 ENSMUST00000019514.9
Calm3
calmodulin 3
chr6_-_39206782 0.510 ENSMUST00000002305.8
Jhdm1d
jumonji C domain-containing histone demethylase 1 homolog D (S. cerevisiae)
chr18_-_43687695 0.508 ENSMUST00000082254.6
Jakmip2
janus kinase and microtubule interacting protein 2
chr5_-_66618752 0.502 ENSMUST00000162366.1
Apbb2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr2_-_136387929 0.498 ENSMUST00000035264.2
ENSMUST00000077200.3
Pak7

p21 protein (Cdc42/Rac)-activated kinase 7

chr7_-_4844665 0.496 ENSMUST00000066041.5
ENSMUST00000172377.1
Shisa7

shisa homolog 7 (Xenopus laevis)

chr9_-_67043953 0.492 ENSMUST00000113690.1
Tpm1
tropomyosin 1, alpha
chr2_-_92370999 0.488 ENSMUST00000176810.1
ENSMUST00000090582.4
Gyltl1b

glycosyltransferase-like 1B

chr1_+_171419027 0.487 ENSMUST00000171362.1
Tstd1
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
chr4_-_124850652 0.486 ENSMUST00000125776.1
1110065P20Rik
RIKEN cDNA 1110065P20 gene
chrX_+_143518671 0.482 ENSMUST00000134402.1
Pak3
p21 protein (Cdc42/Rac)-activated kinase 3
chr11_-_30268169 0.480 ENSMUST00000006629.7
Sptbn1
spectrin beta, non-erythrocytic 1
chr5_+_136967859 0.480 ENSMUST00000001790.5
Cldn15
claudin 15
chr3_+_75557530 0.470 ENSMUST00000161776.1
ENSMUST00000029423.8
Serpini1

serine (or cysteine) peptidase inhibitor, clade I, member 1

chr15_-_84855093 0.468 ENSMUST00000016768.5
Phf21b
PHD finger protein 21B
chr11_-_120348513 0.466 ENSMUST00000071555.6
Actg1
actin, gamma, cytoplasmic 1
chr6_-_50261943 0.465 ENSMUST00000167893.1
Dfna5
deafness, autosomal dominant 5 (human)
chr5_+_150673739 0.460 ENSMUST00000016569.4
ENSMUST00000038900.8
Pds5b

PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)

chr15_+_101412402 0.448 ENSMUST00000068904.8
Krt7
keratin 7
chr1_-_172590463 0.447 ENSMUST00000065679.6
Slamf8
SLAM family member 8
chr11_-_4118778 0.442 ENSMUST00000003681.7
Sec14l2
SEC14-like 2 (S. cerevisiae)
chr18_-_10610124 0.441 ENSMUST00000097670.3
Esco1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chrX_+_7822289 0.435 ENSMUST00000009875.4
Kcnd1
potassium voltage-gated channel, Shal-related family, member 1
chr1_-_167393826 0.430 ENSMUST00000028005.2
Mgst3
microsomal glutathione S-transferase 3
chr17_+_55952623 0.428 ENSMUST00000003274.6
Ebi3
Epstein-Barr virus induced gene 3
chr10_+_17796256 0.427 ENSMUST00000037964.6
Txlnb
taxilin beta
chr4_+_94556546 0.421 ENSMUST00000094969.1
Gm10306
predicted gene 10306
chr19_-_60581013 0.418 ENSMUST00000111460.3
ENSMUST00000081790.7
ENSMUST00000166712.1
Cacul1


CDK2 associated, cullin domain 1


chr18_-_61707583 0.417 ENSMUST00000025472.1
Pcyox1l
prenylcysteine oxidase 1 like
chr9_-_112234956 0.405 ENSMUST00000162097.1
ENSMUST00000159055.1
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr1_-_125912160 0.402 ENSMUST00000159417.1
Lypd1
Ly6/Plaur domain containing 1
chr4_-_44704006 0.402 ENSMUST00000146335.1
Pax5
paired box gene 5
chr18_-_53744509 0.399 ENSMUST00000049811.6
Cep120
centrosomal protein 120
chr9_-_62537036 0.397 ENSMUST00000048043.5
Coro2b
coronin, actin binding protein, 2B
chr11_+_69965396 0.396 ENSMUST00000018713.6
Cldn7
claudin 7
chr15_-_71727815 0.395 ENSMUST00000022953.8
Fam135b
family with sequence similarity 135, member B
chr12_+_73286779 0.392 ENSMUST00000140523.1
Slc38a6
solute carrier family 38, member 6
chr17_-_33951438 0.392 ENSMUST00000087543.2
B3galt4
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
chr7_-_44257378 0.392 ENSMUST00000107945.1
ENSMUST00000118216.1
Acpt

acid phosphatase, testicular

chr13_-_98926374 0.391 ENSMUST00000109401.1
Tnpo1
transportin 1
chrX_-_158043266 0.390 ENSMUST00000026750.8
ENSMUST00000112513.1
Cnksr2

connector enhancer of kinase suppressor of Ras 2

chr14_+_34673888 0.387 ENSMUST00000048263.7
Wapal
wings apart-like homolog (Drosophila)
chr3_-_67515487 0.385 ENSMUST00000178314.1
ENSMUST00000054825.4
Rarres1

retinoic acid receptor responder (tazarotene induced) 1

chr6_+_118066356 0.384 ENSMUST00000164960.1
Rasgef1a
RasGEF domain family, member 1A
chr5_+_137641334 0.384 ENSMUST00000177466.1
ENSMUST00000166099.2
Sap25

sin3 associated polypeptide

chr3_+_16183177 0.382 ENSMUST00000108345.2
ENSMUST00000108346.2
Ythdf3

YTH domain family 3

chr9_-_67760208 0.381 ENSMUST00000068526.5
M5C1000I18Rik
RIKEN cDNA M5C1000I18 gene
chr17_+_87282880 0.376 ENSMUST00000041110.5
ENSMUST00000125875.1
Ttc7

tetratricopeptide repeat domain 7

chr18_-_10610048 0.371 ENSMUST00000115864.1
Esco1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chrX_+_48519245 0.370 ENSMUST00000033430.2
Rab33a
RAB33A, member of RAS oncogene family
chr4_-_14826582 0.368 ENSMUST00000117268.1
Otud6b
OTU domain containing 6B
chr4_-_124850670 0.365 ENSMUST00000163946.1
ENSMUST00000106190.3
1110065P20Rik

RIKEN cDNA 1110065P20 gene

chr12_+_100199435 0.363 ENSMUST00000110082.3
Calm1
calmodulin 1
chr10_-_116473418 0.363 ENSMUST00000087965.4
ENSMUST00000164271.1
Kcnmb4

potassium large conductance calcium-activated channel, subfamily M, beta member 4

chr8_+_65967157 0.359 ENSMUST00000072482.6
March1
membrane-associated ring finger (C3HC4) 1
chr19_+_25610533 0.355 ENSMUST00000048935.4
Dmrt3
doublesex and mab-3 related transcription factor 3
chr16_+_92058270 0.354 ENSMUST00000047429.8
ENSMUST00000113975.2
Mrps6
Slc5a3
mitochondrial ribosomal protein S6
solute carrier family 5 (inositol transporters), member 3
chr16_-_16869255 0.345 ENSMUST00000075017.4
Vpreb1
pre-B lymphocyte gene 1
chr13_+_51846673 0.345 ENSMUST00000021903.2
Gadd45g
growth arrest and DNA-damage-inducible 45 gamma
chr14_+_63606491 0.344 ENSMUST00000119973.2
Xkr6
X Kell blood group precursor related family member 6 homolog
chrX_+_101449078 0.341 ENSMUST00000033674.5
Itgb1bp2
integrin beta 1 binding protein 2
chr3_-_110250963 0.341 ENSMUST00000106567.1
Prmt6
protein arginine N-methyltransferase 6
chr11_+_117849223 0.341 ENSMUST00000081387.4
Birc5
baculoviral IAP repeat-containing 5
chr2_-_103485138 0.336 ENSMUST00000028610.3
Cat
catalase
chr4_+_33031527 0.335 ENSMUST00000029944.6
Ube2j1
ubiquitin-conjugating enzyme E2J 1
chr4_+_41755210 0.334 ENSMUST00000108038.1
ENSMUST00000084695.4
Galt

galactose-1-phosphate uridyl transferase

chr2_-_92371039 0.333 ENSMUST00000068586.6
Gyltl1b
glycosyltransferase-like 1B
chr12_-_76177251 0.330 ENSMUST00000101291.3
ENSMUST00000076634.4
Esr2

estrogen receptor 2 (beta)

chr2_+_121171155 0.329 ENSMUST00000110658.1
Tubgcp4
tubulin, gamma complex associated protein 4
chr6_+_48647224 0.326 ENSMUST00000078223.3
Gimap8
GTPase, IMAP family member 8
chr4_-_124850473 0.325 ENSMUST00000137769.2
1110065P20Rik
RIKEN cDNA 1110065P20 gene
chr3_+_135438280 0.325 ENSMUST00000106291.3
Ube2d3
ubiquitin-conjugating enzyme E2D 3
chr10_+_57486354 0.325 ENSMUST00000079833.4
Hsf2
heat shock factor 2
chr12_-_111908040 0.321 ENSMUST00000163747.2
ENSMUST00000054815.7
Ppp1r13b

protein phosphatase 1, regulatory (inhibitor) subunit 13B

chr19_-_61176309 0.321 ENSMUST00000180168.1
Gm7102
predicted gene 7102

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.5 2.7 GO:0007386 compartment pattern specification(GO:0007386)
0.4 1.6 GO:0061743 motor learning(GO:0061743)
0.3 1.0 GO:0072076 hyaluranon cable assembly(GO:0036118) nephrogenic mesenchyme development(GO:0072076) negative regulation of glomerular mesangial cell proliferation(GO:0072125) negative regulation of glomerulus development(GO:0090194) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.3 0.9 GO:1903903 striated muscle atrophy(GO:0014891) positive regulation of keratinocyte apoptotic process(GO:1902174) regulation of establishment of T cell polarity(GO:1903903)
0.3 0.9 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.2 0.7 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.2 0.9 GO:0090467 regulation of amino acid import(GO:0010958) L-arginine import(GO:0043091) arginine import(GO:0090467)
0.2 0.4 GO:1902623 negative regulation of neutrophil migration(GO:1902623)
0.2 0.2 GO:0048389 intermediate mesoderm development(GO:0048389) pattern specification involved in mesonephros development(GO:0061227) anterior/posterior pattern specification involved in kidney development(GO:0072098)
0.2 0.6 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.2 0.9 GO:0021586 pons maturation(GO:0021586)
0.2 0.8 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.2 0.8 GO:0021836 chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.2 0.6 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.2 1.2 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.2 0.6 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) regulation of connective tissue replacement(GO:1905203)
0.2 0.5 GO:0071550 regulation of muscle atrophy(GO:0014735) death-inducing signaling complex assembly(GO:0071550)
0.2 1.2 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.2 0.7 GO:0010957 negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.2 0.8 GO:0034421 post-translational protein acetylation(GO:0034421)
0.2 0.5 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.2 1.2 GO:0089718 amino acid import across plasma membrane(GO:0089718) L-glutamate import across plasma membrane(GO:0098712)
0.2 1.5 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.1 1.0 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 1.7 GO:0001977 renal system process involved in regulation of blood volume(GO:0001977)
0.1 1.9 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1 0.4 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.1 0.7 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.1 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.1 1.8 GO:0007220 Notch receptor processing(GO:0007220)
0.1 0.3 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.1 0.3 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 0.3 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 0.6 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.1 0.3 GO:0046077 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.1 0.2 GO:0002578 negative regulation of antigen processing and presentation(GO:0002578)
0.1 0.7 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 1.3 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 3.8 GO:0001709 cell fate determination(GO:0001709)
0.1 0.9 GO:1904153 tumor necrosis factor biosynthetic process(GO:0042533) regulation of tumor necrosis factor biosynthetic process(GO:0042534) negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 0.8 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.6 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 1.1 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 1.1 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 0.3 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1 0.9 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 2.9 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 0.8 GO:0021678 third ventricle development(GO:0021678)
0.1 0.5 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.1 0.1 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.1 1.1 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1 0.5 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1 0.2 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.1 1.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 1.6 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.1 1.2 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 0.5 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 0.5 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
0.1 0.2 GO:0046544 development of secondary male sexual characteristics(GO:0046544)
0.1 0.4 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 0.6 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.1 0.4 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.5 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.1 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.2 GO:0019323 D-ribose metabolic process(GO:0006014) pentose catabolic process(GO:0019323)
0.0 0.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.5 GO:0060539 diaphragm development(GO:0060539)
0.0 0.3 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.2 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.7 GO:0001916 positive regulation of T cell mediated cytotoxicity(GO:0001916)
0.0 0.4 GO:0015791 polyol transport(GO:0015791)
0.0 0.8 GO:0015813 L-glutamate transport(GO:0015813)
0.0 0.4 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.5 GO:0009650 UV protection(GO:0009650)
0.0 0.1 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.3 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.2 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.4 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.0 0.2 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.3 GO:0042095 interferon-gamma biosynthetic process(GO:0042095)
0.0 1.1 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0 1.1 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.4 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.2 GO:0002634 regulation of germinal center formation(GO:0002634)
0.0 0.1 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.0 0.3 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.1 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.0 1.5 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.0 0.5 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.0 0.3 GO:0007602 phototransduction(GO:0007602)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.0 0.3 GO:0070228 regulation of lymphocyte apoptotic process(GO:0070228) T cell apoptotic process(GO:0070231) regulation of T cell apoptotic process(GO:0070232)
0.0 0.2 GO:0032929 negative regulation of superoxide anion generation(GO:0032929) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.1 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.4 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.4 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.1 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.1 GO:0071941 nitrogen cycle metabolic process(GO:0071941)
0.0 0.4 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 0.2 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 1.4 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.3 GO:0090205 positive regulation of cholesterol biosynthetic process(GO:0045542) positive regulation of cholesterol metabolic process(GO:0090205)
0.0 0.6 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0071865 regulation of apoptotic process in bone marrow(GO:0071865) negative regulation of apoptotic process in bone marrow(GO:0071866) regulation of osteoclast proliferation(GO:0090289)
0.0 0.5 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.3 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0 0.2 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 0.6 GO:0060074 synapse maturation(GO:0060074)
0.0 0.3 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.1 GO:0032298 positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
0.0 0.3 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.2 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.1 GO:0002339 B cell selection(GO:0002339)
0.0 0.2 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.1 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 0.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.3 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.2 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 0.2 GO:2000370 positive regulation of clathrin-mediated endocytosis(GO:2000370)
0.0 0.1 GO:0015744 succinate transport(GO:0015744)
0.0 0.0 GO:0070944 neutrophil mediated killing of bacterium(GO:0070944)
0.0 0.2 GO:0072010 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.5 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 2.5 GO:0001764 neuron migration(GO:0001764)
0.0 1.4 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.1 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.1 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.2 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.4 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.3 GO:0045103 intermediate filament-based process(GO:0045103)
0.0 0.2 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.0 0.1 GO:1905146 lysosomal protein catabolic process(GO:1905146)
0.0 0.2 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.5 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.0 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.0 GO:0003419 growth plate cartilage chondrocyte proliferation(GO:0003419)
0.0 1.5 GO:0010921 regulation of phosphatase activity(GO:0010921)
0.0 0.3 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.5 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.3 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.3 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.0 GO:1902308 regulation of peptidyl-serine dephosphorylation(GO:1902308)
0.0 0.1 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0 0.2 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 0.2 GO:0042407 cristae formation(GO:0042407)
0.0 0.1 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.4 GO:0043388 positive regulation of DNA binding(GO:0043388)
0.0 0.3 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.3 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.7 GO:0032418 lysosome localization(GO:0032418)
0.0 0.3 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.2 GO:0000028 ribosomal small subunit assembly(GO:0000028)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.3 0.9 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.3 1.5 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.2 0.6 GO:0005940 septin ring(GO:0005940)
0.2 2.0 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.2 1.4 GO:0097427 microtubule bundle(GO:0097427)
0.1 1.9 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.9 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.9 GO:0001520 outer dense fiber(GO:0001520)
0.1 0.5 GO:0031983 vesicle lumen(GO:0031983)
0.1 0.5 GO:0032133 interphase microtubule organizing center(GO:0031021) chromosome passenger complex(GO:0032133)
0.1 0.9 GO:0030478 actin cap(GO:0030478)
0.1 0.6 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.5 GO:0032437 cuticular plate(GO:0032437)
0.1 2.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.3 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 0.5 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.1 0.3 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.1 0.3 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.2 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.0 0.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 0.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 3.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.1 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.6 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.4 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.6 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.3 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.1 GO:0097452 GAIT complex(GO:0097452)
0.0 0.5 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.6 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 2.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.0 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.5 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.2 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.1 GO:0070187 telosome(GO:0070187)
0.0 0.1 GO:0032389 MutLalpha complex(GO:0032389)
0.0 2.8 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 1.0 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.8 GO:0005776 autophagosome(GO:0005776)
0.0 0.5 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.5 GO:0031941 filamentous actin(GO:0031941)
0.0 1.1 GO:0043195 terminal bouton(GO:0043195)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.3 0.8 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2 1.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.2 0.9 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.2 1.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 1.2 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 1.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.2 1.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.2 0.9 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 1.8 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1 0.5 GO:0035877 death effector domain binding(GO:0035877)
0.1 0.5 GO:0004096 aminoacylase activity(GO:0004046) catalase activity(GO:0004096)
0.1 0.7 GO:0023029 MHC class Ib protein binding(GO:0023029)
0.1 0.3 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 0.3 GO:0004127 cytidylate kinase activity(GO:0004127) uridylate kinase activity(GO:0009041)
0.1 1.0 GO:0070700 BMP receptor binding(GO:0070700)
0.1 2.0 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.6 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 1.3 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0033764)
0.1 0.4 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.9 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.1 1.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 1.6 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 0.2 GO:0098809 nitrite reductase activity(GO:0098809)
0.1 0.3 GO:0044020 protein-arginine omega-N monomethyltransferase activity(GO:0035241) histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.1 2.4 GO:0005112 Notch binding(GO:0005112)
0.1 0.2 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.1 0.5 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 1.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.8 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.2 GO:2001069 glycogen binding(GO:2001069)
0.1 1.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.5 GO:0015197 peptide transporter activity(GO:0015197)
0.1 1.0 GO:0030275 LRR domain binding(GO:0030275)
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.6 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.5 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.2 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.4 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 1.9 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.4 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.3 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.3 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 1.7 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 1.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.4 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 1.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.9 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.3 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.5 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 1.4 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.6 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.5 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 1.5 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 1.1 GO:0070888 E-box binding(GO:0070888)
0.0 0.8 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.1 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.0 1.1 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.1 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 8.9 GO:0003779 actin binding(GO:0003779)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.7 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.2 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 4.8 GO:0003924 GTPase activity(GO:0003924)
0.0 1.6 GO:0003774 motor activity(GO:0003774)
0.0 0.2 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.3 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.7 GO:0016209 antioxidant activity(GO:0016209)
0.0 0.2 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 1.3 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.8 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.0 0.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 1.1 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 1.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.1 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.2 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 1.4 GO:0017124 SH3 domain binding(GO:0017124)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.6 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 1.0 PID_ALK2_PATHWAY ALK2 signaling events
0.1 2.5 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 2.9 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 0.6 PID_IL27_PATHWAY IL27-mediated signaling events
0.0 0.6 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 0.3 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 1.0 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 0.8 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.3 SIG_IL4RECEPTOR_IN_B_LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.4 PID_LYMPH_ANGIOGENESIS_PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 1.1 PID_ERBB4_PATHWAY ErbB4 signaling events
0.0 0.3 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.3 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.8 PID_IL12_2PATHWAY IL12-mediated signaling events
0.0 0.8 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 2.0 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.5 PID_ERBB1_DOWNSTREAM_PATHWAY ErbB1 downstream signaling
0.0 0.6 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.5 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.2 PID_ENDOTHELIN_PATHWAY Endothelins
0.0 0.4 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.4 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.3 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 0.5 PID_FOXO_PATHWAY FoxO family signaling
0.0 0.2 PID_EPHA_FWDPATHWAY EPHA forward signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 1.2 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 2.0 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.1 0.6 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 0.3 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 0.8 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.2 REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1 1.2 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.9 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.8 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 2.0 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.5 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.0 0.8 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.1 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 1.0 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 1.0 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.5 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.6 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.3 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.5 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.4 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.6 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.1 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.5 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.1 REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.5 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME_REGULATION_OF_IFNA_SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.1 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.2 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.1 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling