Motif ID: Tlx2

Z-value: 0.715


Transcription factors associated with Tlx2:

Gene SymbolEntrez IDGene Name
Tlx2 ENSMUSG00000068327.3 Tlx2



Activity profile for motif Tlx2.

activity profile for motif Tlx2


Sorted Z-values histogram for motif Tlx2

Sorted Z-values for motif Tlx2



Network of associatons between targets according to the STRING database.



First level regulatory network of Tlx2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_48662740 3.630 ENSMUST00000122009.1
Otx2
orthodenticle homolog 2 (Drosophila)
chr2_-_117342831 2.728 ENSMUST00000178884.1
Rasgrp1
RAS guanyl releasing protein 1
chr14_+_46760526 2.714 ENSMUST00000067426.4
Cdkn3
cyclin-dependent kinase inhibitor 3
chr3_+_134236483 2.703 ENSMUST00000181904.1
ENSMUST00000053048.9
Cxxc4

CXXC finger 4

chr2_-_117342949 2.685 ENSMUST00000102534.4
Rasgrp1
RAS guanyl releasing protein 1
chr14_-_34374617 2.102 ENSMUST00000023826.4
Sncg
synuclein, gamma
chr14_+_115042752 1.973 ENSMUST00000134140.2
Mir17hg
Mir17 host gene 1 (non-protein coding)
chr4_+_154960915 1.953 ENSMUST00000049621.6
Hes5
hairy and enhancer of split 5 (Drosophila)
chr2_-_117342709 1.776 ENSMUST00000173541.1
ENSMUST00000172901.1
ENSMUST00000173252.1
Rasgrp1


RAS guanyl releasing protein 1


chr6_-_72390659 1.680 ENSMUST00000059983.9
Vamp8
vesicle-associated membrane protein 8
chr3_+_159839729 1.557 ENSMUST00000068952.5
Wls
wntless homolog (Drosophila)
chr5_+_146845071 1.510 ENSMUST00000031646.7
Rasl11a
RAS-like, family 11, member A
chr8_-_105637403 1.486 ENSMUST00000182046.1
Gm5914
predicted gene 5914
chr3_+_69004711 1.471 ENSMUST00000042901.8
Smc4
structural maintenance of chromosomes 4
chr6_+_56017489 1.456 ENSMUST00000052827.4
Ppp1r17
protein phosphatase 1, regulatory subunit 17
chr9_+_7764041 1.441 ENSMUST00000052865.9
Tmem123
transmembrane protein 123
chr1_+_134962553 1.441 ENSMUST00000027687.7
Ube2t
ubiquitin-conjugating enzyme E2T (putative)
chr3_-_98339921 1.414 ENSMUST00000065793.5
Phgdh
3-phosphoglycerate dehydrogenase
chr12_+_109540979 1.379 ENSMUST00000129245.1
ENSMUST00000143836.1
ENSMUST00000124106.1
Meg3


maternally expressed 3


chr7_-_98309471 1.371 ENSMUST00000033020.7
Acer3
alkaline ceramidase 3
chr14_-_47394253 1.349 ENSMUST00000177822.1
Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr5_+_45669907 1.337 ENSMUST00000117396.1
Ncapg
non-SMC condensin I complex, subunit G
chr7_-_116334132 1.303 ENSMUST00000170953.1
Rps13
ribosomal protein S13
chr6_+_14901344 1.301 ENSMUST00000115477.1
Foxp2
forkhead box P2
chr12_+_24708984 1.285 ENSMUST00000154588.1
Rrm2
ribonucleotide reductase M2
chr14_-_66868572 1.263 ENSMUST00000022629.8
Dpysl2
dihydropyrimidinase-like 2
chr4_-_41517326 1.245 ENSMUST00000030152.6
ENSMUST00000095126.4
1110017D15Rik

RIKEN cDNA 1110017D15 gene

chr3_+_69004969 1.235 ENSMUST00000136502.1
ENSMUST00000107803.1
Smc4

structural maintenance of chromosomes 4

chr2_-_181039286 1.221 ENSMUST00000067120.7
Chrna4
cholinergic receptor, nicotinic, alpha polypeptide 4
chr3_-_110142996 1.184 ENSMUST00000156177.2
Ntng1
netrin G1
chr14_-_48667508 1.166 ENSMUST00000144465.1
ENSMUST00000133479.1
ENSMUST00000119070.1
ENSMUST00000152018.1
Otx2



orthodenticle homolog 2 (Drosophila)



chr16_+_91225550 1.155 ENSMUST00000035608.8
Olig2
oligodendrocyte transcription factor 2
chr13_+_13784278 1.148 ENSMUST00000021734.7
Gng4
guanine nucleotide binding protein (G protein), gamma 4
chr3_-_145649970 1.128 ENSMUST00000029846.3
Cyr61
cysteine rich protein 61
chr9_+_87015537 1.093 ENSMUST00000058846.4
Ripply2
ripply2 homolog (zebrafish)
chr8_+_94772009 1.088 ENSMUST00000034230.5
Cx3cl1
chemokine (C-X3-C motif) ligand 1
chrX_+_100625737 1.083 ENSMUST00000048962.3
Kif4
kinesin family member 4
chr11_-_69920892 1.065 ENSMUST00000152589.1
ENSMUST00000108612.1
ENSMUST00000108611.1
Eif5a


eukaryotic translation initiation factor 5A


chr2_-_168767029 1.054 ENSMUST00000075044.3
Sall4
sal-like 4 (Drosophila)
chr4_-_129558355 1.036 ENSMUST00000167288.1
ENSMUST00000134336.1
Lck

lymphocyte protein tyrosine kinase

chr4_-_129558387 1.036 ENSMUST00000067240.4
Lck
lymphocyte protein tyrosine kinase
chr11_-_69921057 1.036 ENSMUST00000108609.1
ENSMUST00000108608.1
ENSMUST00000164359.1
Eif5a


eukaryotic translation initiation factor 5A


chr19_-_46044914 1.025 ENSMUST00000026252.7
Ldb1
LIM domain binding 1
chr13_+_53525703 1.018 ENSMUST00000081132.4
Gm5449
predicted pseudogene 5449
chr9_+_111311674 1.004 ENSMUST00000078626.3
Trank1
tetratricopeptide repeat and ankyrin repeat containing 1
chr13_-_74807913 1.004 ENSMUST00000065629.4
Cast
calpastatin
chr10_+_18845071 1.003 ENSMUST00000019998.7
Perp
PERP, TP53 apoptosis effector
chr1_-_175692624 0.982 ENSMUST00000027809.7
Opn3
opsin 3
chr5_-_5749317 0.977 ENSMUST00000015796.2
Steap1
six transmembrane epithelial antigen of the prostate 1
chr6_+_134981998 0.976 ENSMUST00000167323.1
Apold1
apolipoprotein L domain containing 1
chr11_+_82388900 0.959 ENSMUST00000054245.4
ENSMUST00000092852.2
Tmem132e

transmembrane protein 132E

chr17_+_34597852 0.943 ENSMUST00000174496.2
ENSMUST00000015596.3
ENSMUST00000173992.1
Ager


advanced glycosylation end product-specific receptor


chr2_+_104069819 0.935 ENSMUST00000111131.2
ENSMUST00000111132.1
ENSMUST00000129749.1
Cd59b


CD59b antigen


chr11_-_115419917 0.933 ENSMUST00000106537.1
ENSMUST00000043931.2
ENSMUST00000073791.3
Atp5h


ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d


chr9_-_109082372 0.933 ENSMUST00000167504.1
Tma7
translational machinery associated 7 homolog (S. cerevisiae)
chr6_+_50110186 0.933 ENSMUST00000166318.1
ENSMUST00000036236.8
ENSMUST00000036225.8
Mpp6


membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)


chr13_+_45965211 0.927 ENSMUST00000038032.3
5033430I15Rik
RIKEN cDNA 5033430I15 gene
chr9_+_107399858 0.926 ENSMUST00000085092.5
ENSMUST00000164988.2
Cacna2d2

calcium channel, voltage-dependent, alpha 2/delta subunit 2

chr3_+_109573907 0.919 ENSMUST00000106576.2
Vav3
vav 3 oncogene
chr12_+_24708241 0.911 ENSMUST00000020980.5
Rrm2
ribonucleotide reductase M2
chr9_-_10904766 0.910 ENSMUST00000160216.1
Cntn5
contactin 5
chr17_-_35115428 0.908 ENSMUST00000172854.1
ENSMUST00000062657.4
Ly6g5b

lymphocyte antigen 6 complex, locus G5B

chr3_-_113574758 0.902 ENSMUST00000106540.1
Amy1
amylase 1, salivary
chr4_+_130360132 0.886 ENSMUST00000105994.3
Snrnp40
small nuclear ribonucleoprotein 40 (U5)
chr8_-_8690493 0.882 ENSMUST00000048545.8
Arglu1
arginine and glutamate rich 1
chr3_+_8509477 0.881 ENSMUST00000029002.7
Stmn2
stathmin-like 2
chr1_-_138619687 0.880 ENSMUST00000027642.2
Nek7
NIMA (never in mitosis gene a)-related expressed kinase 7
chr11_-_51650813 0.878 ENSMUST00000142721.1
ENSMUST00000156835.1
ENSMUST00000001080.9
N4bp3


NEDD4 binding protein 3


chr1_-_44101982 0.876 ENSMUST00000127923.1
Tex30
testis expressed 30
chr7_+_109519139 0.874 ENSMUST00000143107.1
Rpl27a
ribosomal protein L27A
chr11_+_75999912 0.865 ENSMUST00000066408.5
1700016K19Rik
RIKEN cDNA 1700016K19 gene
chr11_-_76027726 0.862 ENSMUST00000021207.6
Fam101b
family with sequence similarity 101, member B
chr15_-_34443508 0.844 ENSMUST00000079735.5
Rpl30
ribosomal protein L30
chr10_-_103028771 0.839 ENSMUST00000040859.5
Alx1
ALX homeobox 1
chr10_+_91082940 0.838 ENSMUST00000020150.3
Ikbip
IKBKB interacting protein
chr7_-_109438998 0.838 ENSMUST00000121378.1
Stk33
serine/threonine kinase 33
chr7_-_126800354 0.837 ENSMUST00000106348.1
Aldoa
aldolase A, fructose-bisphosphate
chr10_+_78780470 0.833 ENSMUST00000005490.8
Slc1a6
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
chr13_-_49309217 0.830 ENSMUST00000110087.2
Fgd3
FYVE, RhoGEF and PH domain containing 3
chr3_+_32736990 0.830 ENSMUST00000127477.1
ENSMUST00000121778.1
ENSMUST00000154257.1
Ndufb5


NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5


chr11_+_23020464 0.819 ENSMUST00000094363.3
ENSMUST00000151877.1
Fam161a

family with sequence similarity 161, member A

chrX_-_72918411 0.814 ENSMUST00000114551.3
Cetn2
centrin 2
chr4_+_3938888 0.801 ENSMUST00000121110.1
ENSMUST00000108386.1
ENSMUST00000149544.1
Chchd7


coiled-coil-helix-coiled-coil-helix domain containing 7


chr2_+_112379204 0.789 ENSMUST00000028552.3
Katnbl1
katanin p80 subunit B like 1
chr11_-_93965957 0.781 ENSMUST00000021220.3
Nme1
NME/NM23 nucleoside diphosphate kinase 1
chr7_-_109438786 0.776 ENSMUST00000121748.1
Stk33
serine/threonine kinase 33
chr11_+_63128973 0.772 ENSMUST00000108702.1
Pmp22
peripheral myelin protein 22
chr1_-_184033998 0.768 ENSMUST00000050306.5
1700056E22Rik
RIKEN cDNA 1700056E22 gene
chr16_+_14163275 0.768 ENSMUST00000023359.6
ENSMUST00000117958.1
Nde1

nuclear distribution gene E homolog 1 (A nidulans)

chr2_+_151542483 0.757 ENSMUST00000044011.5
Fkbp1a
FK506 binding protein 1a
chr2_+_60209887 0.752 ENSMUST00000102748.4
ENSMUST00000102747.1
March7

membrane-associated ring finger (C3HC4) 7

chr9_+_123034731 0.742 ENSMUST00000026893.4
Tgm4
transglutaminase 4 (prostate)
chr9_-_10904697 0.741 ENSMUST00000162484.1
Cntn5
contactin 5
chr9_-_61914538 0.740 ENSMUST00000008036.7
Rplp1
ribosomal protein, large, P1
chr6_+_86371489 0.727 ENSMUST00000089558.5
Snrpg
small nuclear ribonucleoprotein polypeptide G
chr1_-_87156127 0.724 ENSMUST00000160810.1
Ecel1
endothelin converting enzyme-like 1
chr9_-_88522876 0.720 ENSMUST00000180563.2
ENSMUST00000183030.1
ENSMUST00000182232.1
Snhg5


small nucleolar RNA host gene 5


chr19_+_23675839 0.718 ENSMUST00000056396.5
Gm6563
predicted pseudogene 6563
chr3_+_103171655 0.716 ENSMUST00000005830.8
Bcas2
breast carcinoma amplified sequence 2
chr11_-_5707658 0.711 ENSMUST00000154330.1
Mrps24
mitochondrial ribosomal protein S24
chr9_-_121839460 0.704 ENSMUST00000135986.2
Ccdc13
coiled-coil domain containing 13
chr7_-_126800036 0.702 ENSMUST00000133514.1
ENSMUST00000151137.1
Aldoa

aldolase A, fructose-bisphosphate

chr6_-_119330668 0.702 ENSMUST00000112756.1
Lrtm2
leucine-rich repeats and transmembrane domains 2
chr15_+_54745702 0.700 ENSMUST00000050027.8
Nov
nephroblastoma overexpressed gene
chr2_-_181039160 0.693 ENSMUST00000108851.1
Chrna4
cholinergic receptor, nicotinic, alpha polypeptide 4
chr11_+_101442440 0.693 ENSMUST00000107249.1
Rpl27
ribosomal protein L27
chr11_+_101442298 0.692 ENSMUST00000077856.6
Rpl27
ribosomal protein L27
chr2_-_174472949 0.691 ENSMUST00000016401.8
Slmo2
slowmo homolog 2 (Drosophila)
chr15_-_34443209 0.688 ENSMUST00000009039.5
Rpl30
ribosomal protein L30
chr5_-_143527977 0.688 ENSMUST00000100489.3
ENSMUST00000080537.7
Rac1

RAS-related C3 botulinum substrate 1

chr17_+_30005029 0.687 ENSMUST00000057897.7
Zfand3
zinc finger, AN1-type domain 3
chr14_+_54426902 0.686 ENSMUST00000010550.7
Mrpl52
mitochondrial ribosomal protein L52
chr10_-_67912620 0.686 ENSMUST00000064656.7
Zfp365
zinc finger protein 365
chr2_+_103073669 0.686 ENSMUST00000011055.6
Apip
APAF1 interacting protein
chr6_-_115808736 0.684 ENSMUST00000081840.3
Rpl32
ribosomal protein L32
chr17_+_24632671 0.682 ENSMUST00000047611.2
Nthl1
nth (endonuclease III)-like 1 (E.coli)
chr10_-_80399478 0.681 ENSMUST00000092295.3
ENSMUST00000105349.1
Mbd3

methyl-CpG binding domain protein 3

chr5_+_107900502 0.679 ENSMUST00000082223.6
Rpl5
ribosomal protein L5
chr1_+_171437535 0.679 ENSMUST00000043839.4
F11r
F11 receptor
chr7_-_118443549 0.665 ENSMUST00000081574.4
Syt17
synaptotagmin XVII
chr19_-_28680077 0.661 ENSMUST00000162022.1
ENSMUST00000112612.2
Glis3

GLIS family zinc finger 3

chr7_-_142576492 0.658 ENSMUST00000140716.1
H19
H19 fetal liver mRNA
chr16_+_14163316 0.656 ENSMUST00000115795.2
Nde1
nuclear distribution gene E homolog 1 (A nidulans)
chr5_-_5380185 0.644 ENSMUST00000030763.6
Cdk14
cyclin-dependent kinase 14
chr4_-_136053343 0.641 ENSMUST00000102536.4
Rpl11
ribosomal protein L11
chr6_-_119330723 0.641 ENSMUST00000068351.7
Lrtm2
leucine-rich repeats and transmembrane domains 2
chr14_+_74640840 0.639 ENSMUST00000036653.3
Htr2a
5-hydroxytryptamine (serotonin) receptor 2A
chr6_-_13871477 0.637 ENSMUST00000139231.1
2610001J05Rik
RIKEN cDNA 2610001J05 gene
chr11_+_78178651 0.634 ENSMUST00000092880.7
ENSMUST00000127587.1
ENSMUST00000108338.1
Tlcd1


TLC domain containing 1


chr16_-_45693658 0.631 ENSMUST00000114562.2
ENSMUST00000036617.7
Tmprss7

transmembrane serine protease 7

chrX_-_72918284 0.617 ENSMUST00000152200.1
Cetn2
centrin 2
chr12_+_80945500 0.614 ENSMUST00000094693.4
Srsf5
serine/arginine-rich splicing factor 5
chr11_+_6658510 0.613 ENSMUST00000045374.7
Ramp3
receptor (calcitonin) activity modifying protein 3
chr4_+_130047914 0.613 ENSMUST00000142293.1
Col16a1
collagen, type XVI, alpha 1
chr10_+_94036001 0.608 ENSMUST00000020208.4
Fgd6
FYVE, RhoGEF and PH domain containing 6
chr5_-_121527186 0.606 ENSMUST00000152270.1
Mapkapk5
MAP kinase-activated protein kinase 5
chr10_-_80399389 0.606 ENSMUST00000105348.1
Mbd3
methyl-CpG binding domain protein 3
chr19_-_60874526 0.599 ENSMUST00000025961.6
Prdx3
peroxiredoxin 3
chr2_+_34772089 0.597 ENSMUST00000028222.6
ENSMUST00000100171.2
Hspa5

heat shock protein 5

chr2_+_167062934 0.595 ENSMUST00000125674.1
1500012F01Rik
RIKEN cDNA 1500012F01 gene
chr17_-_84682932 0.594 ENSMUST00000066175.3
Abcg5
ATP-binding cassette, sub-family G (WHITE), member 5
chr6_+_108660772 0.589 ENSMUST00000163617.1
Bhlhe40
basic helix-loop-helix family, member e40
chr6_+_125192154 0.586 ENSMUST00000032485.5
Mrpl51
mitochondrial ribosomal protein L51
chr18_-_3337539 0.584 ENSMUST00000142690.1
ENSMUST00000025069.4
ENSMUST00000082141.5
ENSMUST00000165086.1
ENSMUST00000149803.1
Crem




cAMP responsive element modulator




chr17_-_36958206 0.579 ENSMUST00000172823.1
Znrd1
zinc ribbon domain containing, 1
chr5_+_107900859 0.575 ENSMUST00000153590.1
Rpl5
ribosomal protein L5
chrX_-_93832106 0.572 ENSMUST00000045748.6
Pdk3
pyruvate dehydrogenase kinase, isoenzyme 3
chr11_-_78984831 0.572 ENSMUST00000073001.4
ENSMUST00000108269.3
Lgals9

lectin, galactose binding, soluble 9

chrX_-_142390491 0.570 ENSMUST00000112904.1
ENSMUST00000112903.1
ENSMUST00000033634.4
Acsl4


acyl-CoA synthetase long-chain family member 4


chr4_+_3938904 0.570 ENSMUST00000120732.1
ENSMUST00000041122.4
ENSMUST00000121651.1
ENSMUST00000121210.1
ENSMUST00000119307.1
ENSMUST00000123769.1
Chchd7





coiled-coil-helix-coiled-coil-helix domain containing 7





chr4_-_137766474 0.569 ENSMUST00000139951.1
Alpl
alkaline phosphatase, liver/bone/kidney
chrX_+_74270812 0.568 ENSMUST00000008826.7
ENSMUST00000151702.1
ENSMUST00000074085.5
ENSMUST00000135690.1
Rpl10



ribosomal protein L10



chr19_-_5729618 0.566 ENSMUST00000116558.2
ENSMUST00000099955.3
ENSMUST00000161368.1
Fam89b


family with sequence similarity 89, member B


chr12_+_80945520 0.565 ENSMUST00000110354.1
ENSMUST00000110352.3
ENSMUST00000110351.1
ENSMUST00000110356.2
Srsf5



serine/arginine-rich splicing factor 5



chr19_-_4163285 0.563 ENSMUST00000118483.1
ENSMUST00000025749.7
Rps6kb2

ribosomal protein S6 kinase, polypeptide 2

chr6_+_108660616 0.563 ENSMUST00000032194.4
Bhlhe40
basic helix-loop-helix family, member e40
chr9_-_123678782 0.559 ENSMUST00000170591.1
ENSMUST00000171647.1
Slc6a20a

solute carrier family 6 (neurotransmitter transporter), member 20A

chr13_-_66905322 0.558 ENSMUST00000021993.4
Uqcrb
ubiquinol-cytochrome c reductase binding protein
chr1_+_167689552 0.555 ENSMUST00000028003.7
Lmx1a
LIM homeobox transcription factor 1 alpha
chr9_-_58201705 0.554 ENSMUST00000163200.1
ENSMUST00000165276.1
Islr2

immunoglobulin superfamily containing leucine-rich repeat 2

chr19_+_6401675 0.549 ENSMUST00000113471.1
ENSMUST00000113469.2
Rasgrp2

RAS, guanyl releasing protein 2

chrY_-_1245685 0.545 ENSMUST00000143286.1
ENSMUST00000137048.1
ENSMUST00000069309.7
ENSMUST00000139365.1
Uty



ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome



chr9_-_123678873 0.544 ENSMUST00000040960.6
Slc6a20a
solute carrier family 6 (neurotransmitter transporter), member 20A
chr10_+_40883819 0.543 ENSMUST00000105509.1
Wasf1
WAS protein family, member 1
chr12_+_41024090 0.541 ENSMUST00000132121.1
Immp2l
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr17_+_35439155 0.540 ENSMUST00000071951.6
ENSMUST00000078205.7
ENSMUST00000116598.3
ENSMUST00000076256.7
H2-Q7



histocompatibility 2, Q region locus 7



chr6_-_23839137 0.539 ENSMUST00000166458.2
ENSMUST00000142913.2
ENSMUST00000115357.1
ENSMUST00000069074.7
ENSMUST00000115361.2
ENSMUST00000018122.7
ENSMUST00000115355.1
ENSMUST00000115356.2
Cadps2







Ca2+-dependent activator protein for secretion 2







chr3_-_113574242 0.537 ENSMUST00000142505.2
Amy1
amylase 1, salivary
chr8_+_92827273 0.531 ENSMUST00000034187.7
Mmp2
matrix metallopeptidase 2
chr6_+_35252692 0.530 ENSMUST00000130875.1
1810058I24Rik
RIKEN cDNA 1810058I24 gene
chr2_-_30903255 0.530 ENSMUST00000102852.3
Ptges
prostaglandin E synthase
chr9_-_82975475 0.522 ENSMUST00000034787.5
Phip
pleckstrin homology domain interacting protein
chr11_-_52282564 0.521 ENSMUST00000086844.3
Tcf7
transcription factor 7, T cell specific
chr10_+_11609256 0.519 ENSMUST00000052902.7
Gm9797
predicted pseudogene 9797
chr11_-_6444352 0.515 ENSMUST00000093346.5
ENSMUST00000109737.2
H2afv

H2A histone family, member V

chr11_-_78984946 0.513 ENSMUST00000108268.3
Lgals9
lectin, galactose binding, soluble 9
chrX_-_142390334 0.513 ENSMUST00000112907.1
Acsl4
acyl-CoA synthetase long-chain family member 4
chr12_+_41024329 0.509 ENSMUST00000134965.1
Immp2l
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr4_-_118490030 0.509 ENSMUST00000047421.5
Tie1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr7_-_16924114 0.506 ENSMUST00000019514.9
Calm3
calmodulin 3
chr13_+_21754067 0.506 ENSMUST00000091709.2
Hist1h2bn
histone cluster 1, H2bn
chr7_+_46796088 0.505 ENSMUST00000006774.4
ENSMUST00000165031.1
Gtf2h1

general transcription factor II H, polypeptide 1

chr13_-_104816908 0.504 ENSMUST00000022228.6
Cwc27
CWC27 spliceosome-associated protein homolog (S. cerevisiae)
chr14_+_55015454 0.503 ENSMUST00000022815.8
Ngdn
neuroguidin, EIF4E binding protein
chr3_-_84479418 0.502 ENSMUST00000091002.1
Fhdc1
FH2 domain containing 1
chr2_-_6130117 0.502 ENSMUST00000126551.1
ENSMUST00000054254.5
ENSMUST00000114942.2
Proser2


proline and serine rich 2


chr2_-_30093642 0.502 ENSMUST00000102865.4
Zdhhc12
zinc finger, DHHC domain containing 12
chr19_-_34255325 0.501 ENSMUST00000039631.8
Acta2
actin, alpha 2, smooth muscle, aorta
chr5_-_100674230 0.501 ENSMUST00000031262.7
Coq2
coenzyme Q2 homolog, prenyltransferase (yeast)
chr1_-_193370225 0.500 ENSMUST00000169907.1
Camk1g
calcium/calmodulin-dependent protein kinase I gamma
chr16_-_42340595 0.498 ENSMUST00000102817.4
Gap43
growth associated protein 43
chr11_-_21572193 0.498 ENSMUST00000102874.4
Mdh1
malate dehydrogenase 1, NAD (soluble)
chr19_-_44552831 0.493 ENSMUST00000166808.1
Gm20538
predicted gene 20538
chr7_-_30563184 0.493 ENSMUST00000043898.6
Psenen
presenilin enhancer 2 homolog (C. elegans)
chr6_+_42350000 0.491 ENSMUST00000164375.1
Zyx
zyxin
chr2_-_120154600 0.491 ENSMUST00000028755.7
Ehd4
EH-domain containing 4
chr11_+_115420059 0.491 ENSMUST00000103035.3
Kctd2
potassium channel tetramerisation domain containing 2
chr10_-_60219260 0.487 ENSMUST00000135158.2
Chst3
carbohydrate (chondroitin 6/keratan) sulfotransferase 3
chr18_-_31317043 0.487 ENSMUST00000139924.1
ENSMUST00000153060.1
Rit2

Ras-like without CAAX 2

chr15_+_54571358 0.486 ENSMUST00000025356.2
Mal2
mal, T cell differentiation protein 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.8 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.8 7.2 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.6 1.9 GO:1903048 regulation of acetylcholine-gated cation channel activity(GO:1903048)
0.6 1.9 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.6 1.7 GO:0090187 zymogen granule exocytosis(GO:0070625) positive regulation of pancreatic juice secretion(GO:0090187)
0.5 1.6 GO:0061357 Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356) positive regulation of Wnt protein secretion(GO:0061357)
0.5 2.0 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
0.5 1.4 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.5 0.5 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.5 1.4 GO:0006566 threonine metabolic process(GO:0006566)
0.4 1.3 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.4 1.2 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.4 1.5 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.4 1.1 GO:1902713 regulation of interferon-gamma secretion(GO:1902713)
0.4 2.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.4 1.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.3 2.7 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.3 1.0 GO:0018298 protein-chromophore linkage(GO:0018298)
0.3 0.9 GO:1905203 regulation of connective tissue replacement(GO:1905203)
0.3 0.9 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.3 1.1 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.3 2.1 GO:0046645 positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645) positive regulation of uterine smooth muscle contraction(GO:0070474)
0.2 0.7 GO:0033566 gamma-tubulin complex localization(GO:0033566)
0.2 0.7 GO:0006296 base-excision repair, AP site formation(GO:0006285) nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.2 1.1 GO:0060591 chondroblast differentiation(GO:0060591)
0.2 0.6 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.2 0.6 GO:0030300 regulation of intestinal cholesterol absorption(GO:0030300)
0.2 1.0 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.2 0.9 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.2 0.3 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.2 0.7 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509) pyroptosis(GO:0070269)
0.2 1.0 GO:0002934 desmosome organization(GO:0002934)
0.2 0.6 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.2 0.9 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.2 0.5 GO:0001803 antibody-dependent cellular cytotoxicity(GO:0001788) type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.2 0.5 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.2 1.5 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.4 GO:2000319 negative regulation of T-helper 17 type immune response(GO:2000317) regulation of T-helper 17 cell differentiation(GO:2000319) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.1 1.3 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 0.7 GO:0007320 insemination(GO:0007320)
0.1 0.3 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.1 1.0 GO:0007343 egg activation(GO:0007343)
0.1 0.6 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 0.6 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.1 0.4 GO:0010752 signal complex assembly(GO:0007172) regulation of cGMP-mediated signaling(GO:0010752)
0.1 0.7 GO:0032627 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667)
0.1 2.4 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 0.4 GO:0001951 intestinal D-glucose absorption(GO:0001951) terminal web assembly(GO:1902896)
0.1 0.4 GO:0046110 xanthine metabolic process(GO:0046110)
0.1 0.5 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.1 0.4 GO:0070889 platelet alpha granule organization(GO:0070889) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162)
0.1 0.4 GO:0007521 muscle cell fate determination(GO:0007521) mammary placode formation(GO:0060596)
0.1 1.4 GO:0046512 sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.1 1.1 GO:0032306 regulation of prostaglandin secretion(GO:0032306)
0.1 0.6 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.1 0.5 GO:0072592 oxygen metabolic process(GO:0072592)
0.1 0.5 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 1.1 GO:0015838 proline transport(GO:0015824) amino-acid betaine transport(GO:0015838)
0.1 0.9 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 1.1 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 1.9 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.1 0.6 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 0.4 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.1 1.1 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.1 0.5 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.1 0.5 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 1.1 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 0.3 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.1 0.5 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.1 0.6 GO:1990416 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 0.6 GO:0090400 stress-induced premature senescence(GO:0090400)
0.1 0.3 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of epithelial cell differentiation involved in kidney development(GO:2000698) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.1 0.5 GO:0006108 malate metabolic process(GO:0006108)
0.1 0.4 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 1.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.5 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 0.3 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.1 0.5 GO:0097491 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.1 0.5 GO:1990504 dense core granule exocytosis(GO:1990504)
0.1 0.4 GO:2001025 positive regulation of response to drug(GO:2001025)
0.1 0.2 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.1 0.3 GO:0090365 regulation of mRNA modification(GO:0090365)
0.1 0.2 GO:2000987 positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.1 0.8 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 1.3 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.1 0.8 GO:0060347 heart trabecula formation(GO:0060347)
0.1 0.2 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.1 0.7 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 0.3 GO:0097211 prolactin secretion(GO:0070459) response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.1 1.3 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.1 0.4 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.7 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.1 0.3 GO:0002339 B cell selection(GO:0002339)
0.1 0.1 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 0.5 GO:0002681 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.1 0.8 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 0.1 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.1 1.5 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1 0.5 GO:0006071 glycerol metabolic process(GO:0006071)
0.1 1.4 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 1.4 GO:0009648 photoperiodism(GO:0009648)
0.1 0.1 GO:0099527 postsynapse to nucleus signaling pathway(GO:0099527)
0.1 0.5 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.3 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.1 0.6 GO:0002643 regulation of tolerance induction(GO:0002643)
0.1 0.7 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.1 0.5 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1 0.9 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.1 0.6 GO:1904948 midbrain dopaminergic neuron differentiation(GO:1904948)
0.0 1.7 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.1 GO:0070844 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0 0.7 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.2 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.0 0.5 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.3 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.9 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.3 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.4 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.8 GO:0032060 bleb assembly(GO:0032060)
0.0 0.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.2 GO:0015744 succinate transport(GO:0015744)
0.0 0.4 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.3 GO:0015074 DNA integration(GO:0015074)
0.0 1.4 GO:0007099 centriole replication(GO:0007099)
0.0 1.0 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 1.7 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 1.7 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 0.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.2 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.0 0.4 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.3 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.0 0.1 GO:0032382 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373)
0.0 0.3 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.6 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.1 GO:0051316 attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation(GO:0051316)
0.0 0.2 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.3 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.0 2.2 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.2 GO:0060343 trabecula formation(GO:0060343)
0.0 0.2 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.1 GO:0036233 glycine import(GO:0036233)
0.0 0.8 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.2 GO:0098734 protein depalmitoylation(GO:0002084) negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005) macromolecule depalmitoylation(GO:0098734)
0.0 0.3 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.9 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.0 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.0 0.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.4 GO:0033262 regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0 0.5 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.3 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.0 1.6 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.4 GO:1900153 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.6 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 1.2 GO:0070206 protein trimerization(GO:0070206)
0.0 3.0 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.5 GO:0014829 vascular smooth muscle contraction(GO:0014829)
0.0 0.5 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.3 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.8 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.9 GO:0051591 response to cAMP(GO:0051591)
0.0 0.2 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 2.3 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.1 GO:0009597 detection of virus(GO:0009597)
0.0 0.8 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.0 0.6 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.5 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 0.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0015786 UDP-glucose transport(GO:0015786)
0.0 1.3 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.6 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.1 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.0 0.2 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.1 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553) regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.0 0.1 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0 0.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.8 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.0 GO:0010863 positive regulation of phospholipase C activity(GO:0010863)
0.0 0.6 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.3 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.2 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.5 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.0 GO:0006083 acetate metabolic process(GO:0006083)
0.0 0.0 GO:1900426 positive regulation of defense response to bacterium(GO:1900426)
0.0 1.4 GO:0016052 carbohydrate catabolic process(GO:0016052)
0.0 0.1 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.3 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.2 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.5 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.0 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.0 0.9 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.0 0.1 GO:0051956 negative regulation of amino acid transport(GO:0051956)
0.0 0.2 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.0 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.0 0.4 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 1.1 GO:0010921 regulation of phosphatase activity(GO:0010921)
0.0 1.4 GO:0006364 rRNA processing(GO:0006364)
0.0 0.2 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.3 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.3 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.2 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.3 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.0 0.9 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.4 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.2 GO:0048266 behavioral response to pain(GO:0048266)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.4 4.0 GO:0000796 condensin complex(GO:0000796)
0.4 1.4 GO:0071942 XPC complex(GO:0071942)
0.4 1.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.2 2.1 GO:0005642 annulate lamellae(GO:0005642)
0.2 1.9 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.2 0.5 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.2 1.7 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1 2.8 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 1.2 GO:0002177 manchette(GO:0002177)
0.1 0.4 GO:0005940 septin ring(GO:0005940)
0.1 0.6 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 0.6 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1 0.5 GO:0097447 dendritic tree(GO:0097447)
0.1 8.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.3 GO:0001725 stress fiber(GO:0001725) actin filament bundle(GO:0032432) actomyosin(GO:0042641) contractile actin filament bundle(GO:0097517)
0.1 2.8 GO:0000242 pericentriolar material(GO:0000242)
0.1 1.5 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 1.1 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 0.4 GO:0000243 commitment complex(GO:0000243)
0.1 0.5 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.3 GO:0055087 Ski complex(GO:0055087)
0.1 0.3 GO:0071914 prominosome(GO:0071914)
0.1 0.9 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 0.4 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 1.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.4 GO:1990357 terminal web(GO:1990357)
0.1 0.8 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 2.3 GO:0071011 precatalytic spliceosome(GO:0071011)
0.1 0.3 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 0.6 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 1.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.9 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.9 GO:0070852 cell body fiber(GO:0070852)
0.1 0.8 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.5 GO:0000439 core TFIIH complex(GO:0000439)
0.1 0.4 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 1.9 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 1.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.3 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.4 GO:0098533 ATPase dependent transmembrane transport complex(GO:0098533)
0.0 0.4 GO:0070652 HAUS complex(GO:0070652)
0.0 0.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.7 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 0.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.4 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.6 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.3 GO:0045298 tubulin complex(GO:0045298)
0.0 0.9 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 0.3 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 2.0 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 1.7 GO:0015935 small ribosomal subunit(GO:0015935)
0.0 0.8 GO:0043218 compact myelin(GO:0043218)
0.0 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.3 GO:0061574 ASAP complex(GO:0061574)
0.0 0.8 GO:0005921 gap junction(GO:0005921)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.5 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.0 1.0 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.8 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 1.2 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.4 GO:1990635 proximal dendrite(GO:1990635)
0.0 2.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 5.4 GO:0030426 growth cone(GO:0030426)
0.0 1.1 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.4 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.1 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.3 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 1.1 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.1 GO:0071008 B cell receptor complex(GO:0019815) U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.7 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.1 GO:0097441 basilar dendrite(GO:0097441)
0.0 0.5 GO:0032040 small-subunit processome(GO:0032040)
0.0 1.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.5 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.6 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.5 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.6 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.3 GO:0045120 pronucleus(GO:0045120)
0.0 0.5 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.7 GO:0005844 polysome(GO:0005844)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 1.8 GO:0043679 axon terminus(GO:0043679)
0.0 2.2 GO:0043209 myelin sheath(GO:0043209)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.2 GO:0000800 lateral element(GO:0000800)
0.0 1.5 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 7.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.5 1.4 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.4 2.2 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.4 2.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.3 1.0 GO:0009881 photoreceptor activity(GO:0009881)
0.3 1.0 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.3 1.9 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.3 1.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.3 1.8 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.2 1.4 GO:0017040 ceramidase activity(GO:0017040)
0.2 0.6 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.2 1.7 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.2 0.4 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725)
0.2 1.2 GO:0043426 MRF binding(GO:0043426)
0.2 1.5 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.2 1.9 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.2 0.6 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.2 0.7 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2 1.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 1.1 GO:0016936 galactoside binding(GO:0016936)
0.2 0.9 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 1.5 GO:0030274 LIM domain binding(GO:0030274)
0.2 1.6 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.2 0.5 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.1 0.6 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.6 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 2.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 1.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 0.7 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.1 0.4 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 0.7 GO:0031628 opioid receptor binding(GO:0031628)
0.1 0.5 GO:0004667 prostaglandin-D synthase activity(GO:0004667) prostaglandin-E synthase activity(GO:0050220)
0.1 1.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.5 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.1 1.1 GO:1990446 U1 snRNP binding(GO:1990446)
0.1 0.9 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 0.6 GO:0097643 amylin receptor activity(GO:0097643)
0.1 0.5 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.1 1.2 GO:0050733 RS domain binding(GO:0050733)
0.1 3.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.7 GO:0050694 galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 0.4 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 0.9 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1 0.5 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.1 1.1 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.5 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.5 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.3 GO:0035473 lipase binding(GO:0035473)
0.1 1.8 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.5 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 0.9 GO:0044548 S100 protein binding(GO:0044548)
0.1 0.4 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.5 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.1 0.6 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.8 GO:0048185 activin binding(GO:0048185)
0.1 0.8 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 0.8 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 0.4 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.5 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 0.4 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 0.6 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 0.5 GO:0046790 virion binding(GO:0046790)
0.1 0.2 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.1 0.4 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.2 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.1 0.3 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 0.3 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 2.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 1.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 8.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 0.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.9 GO:0001848 complement binding(GO:0001848)
0.0 0.3 GO:1990405 protein antigen binding(GO:1990405)
0.0 0.2 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 1.2 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.5 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.8 GO:0001968 fibronectin binding(GO:0001968)
0.0 5.1 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.2 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0 0.2 GO:0070976 calcium-independent protein kinase C activity(GO:0004699) TIR domain binding(GO:0070976)
0.0 0.6 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.3 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 1.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0050632 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
0.0 1.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386) potassium ion antiporter activity(GO:0022821)
0.0 0.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.6 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.5 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.5 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.2 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.9 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.2 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 1.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.7 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.1 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.9 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 2.0 GO:0046983 protein dimerization activity(GO:0046983)
0.0 0.6 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.3 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.5 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.3 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 1.4 GO:0051287 NAD binding(GO:0051287)
0.0 0.2 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 1.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 2.9 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 2.2 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 1.3 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.8 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.1 GO:0036004 GAF domain binding(GO:0036004)
0.0 0.3 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.0 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.0 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0001639 PLC activating G-protein coupled glutamate receptor activity(GO:0001639) A2A adenosine receptor binding(GO:0031687) G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.0 0.7 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.5 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.0 GO:0033691 sialic acid binding(GO:0033691)
0.0 1.0 GO:0005178 integrin binding(GO:0005178)
0.0 0.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 1.3 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.0 0.4 GO:0005179 hormone activity(GO:0005179)
0.0 0.4 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.2 GO:0071889 14-3-3 protein binding(GO:0071889)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 0.9 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.2 7.5 PID_RAS_PATHWAY Regulation of Ras family activation
0.1 1.8 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.1 1.6 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.1 3.9 PID_AURORA_B_PATHWAY Aurora B signaling
0.1 2.1 PID_NFKAPPAB_ATYPICAL_PATHWAY Atypical NF-kappaB pathway
0.1 0.8 PID_ALK2_PATHWAY ALK2 signaling events
0.0 0.5 PID_CONE_PATHWAY Visual signal transduction: Cones
0.0 0.4 PID_AVB3_OPN_PATHWAY Osteopontin-mediated events
0.0 1.4 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 0.5 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 0.6 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 3.9 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.6 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 0.9 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling
0.0 1.1 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.8 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.8 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.4 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 1.8 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 0.3 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 0.5 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.0 0.6 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.8 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.0 2.8 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.3 PID_CDC42_PATHWAY CDC42 signaling events
0.0 0.6 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.0 1.5 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.4 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 0.5 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 1.7 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 0.4 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 0.5 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.1 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2 1.9 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.2 7.8 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.2 0.6 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
0.1 3.2 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.1 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 9.8 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.1 0.3 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 2.1 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 1.6 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.1 1.3 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.1 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.1 0.5 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.1 1.1 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 0.8 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 1.4 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 0.8 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 0.7 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 0.7 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 0.7 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.1 0.5 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.1 1.4 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 2.0 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 0.9 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.8 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.5 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.7 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 1.2 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.6 REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.9 REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 1.1 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.4 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.5 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.6 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.5 REACTOME_ACTIVATION_OF_KAINATE_RECEPTORS_UPON_GLUTAMATE_BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
0.0 1.1 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.0 0.5 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.9 REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.9 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.0 1.6 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 0.2 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.5 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.0 0.9 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.5 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.5 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.4 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.9 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.4 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.2 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 2.2 REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 0.2 REACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.9 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.0 0.5 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.5 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.4 REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 0.4 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.3 REACTOME_SIGNALING_BY_PDGF Genes involved in Signaling by PDGF
0.0 0.1 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.1 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.5 REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS Genes involved in G alpha (z) signalling events
0.0 0.2 REACTOME_ENOS_ACTIVATION_AND_REGULATION Genes involved in eNOS activation and regulation
0.0 0.2 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.4 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression