Motif ID: Tbx19

Z-value: 0.638


Transcription factors associated with Tbx19:

Gene SymbolEntrez IDGene Name
Tbx19 ENSMUSG00000026572.5 Tbx19



Activity profile for motif Tbx19.

activity profile for motif Tbx19


Sorted Z-values histogram for motif Tbx19

Sorted Z-values for motif Tbx19



Network of associatons between targets according to the STRING database.



First level regulatory network of Tbx19

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_130936172 3.027 ENSMUST00000006367.7
Htra1
HtrA serine peptidase 1
chr2_-_113758638 2.930 ENSMUST00000099575.3
Grem1
gremlin 1
chr3_+_94693556 2.246 ENSMUST00000090848.3
ENSMUST00000173981.1
ENSMUST00000173849.1
ENSMUST00000174223.1
Selenbp2



selenium binding protein 2



chr18_-_82406777 2.199 ENSMUST00000065224.6
Galr1
galanin receptor 1
chr19_+_5474681 2.115 ENSMUST00000165485.1
ENSMUST00000166253.1
ENSMUST00000167371.1
ENSMUST00000167855.1
ENSMUST00000070118.7
Efemp2




epidermal growth factor-containing fibulin-like extracellular matrix protein 2




chr6_+_90465287 1.726 ENSMUST00000113530.1
Klf15
Kruppel-like factor 15
chrY_+_897782 1.587 ENSMUST00000055032.7
Kdm5d
lysine (K)-specific demethylase 5D
chr14_+_115042752 1.539 ENSMUST00000134140.2
Mir17hg
Mir17 host gene 1 (non-protein coding)
chr2_+_179442427 1.415 ENSMUST00000000314.6
Cdh4
cadherin 4
chr3_-_97610156 1.399 ENSMUST00000029730.4
Chd1l
chromodomain helicase DNA binding protein 1-like
chr10_-_86011833 1.267 ENSMUST00000105304.1
ENSMUST00000061699.5
Bpifc

BPI fold containing family C

chr5_-_92278155 1.237 ENSMUST00000159345.1
ENSMUST00000113102.3
Naaa

N-acylethanolamine acid amidase

chr17_+_6978860 1.226 ENSMUST00000089119.5
ENSMUST00000179728.1
Rnaset2b

ribonuclease T2B

chr11_-_60046477 1.184 ENSMUST00000000310.7
ENSMUST00000102693.2
ENSMUST00000148512.1
Pemt


phosphatidylethanolamine N-methyltransferase


chr14_-_66124482 1.172 ENSMUST00000070515.1
Ephx2
epoxide hydrolase 2, cytoplasmic
chr7_+_48959089 1.144 ENSMUST00000183659.1
Nav2
neuron navigator 2
chr6_-_119467210 1.104 ENSMUST00000118120.1
Wnt5b
wingless-related MMTV integration site 5B
chr5_-_115484297 1.033 ENSMUST00000112067.1
Sirt4
sirtuin 4
chr2_+_175010241 0.890 ENSMUST00000109069.1
ENSMUST00000109070.2
Gm14444

predicted gene 14444

chr6_+_17749170 0.886 ENSMUST00000053148.7
ENSMUST00000115417.3
St7

suppression of tumorigenicity 7

chr2_-_175067763 0.800 ENSMUST00000072895.3
ENSMUST00000109066.1
Gm14393

predicted gene 14393

chr2_-_177578199 0.757 ENSMUST00000108945.1
ENSMUST00000108943.1
Gm14406

predicted gene 14406

chr13_+_58806564 0.749 ENSMUST00000109838.2
Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chr2_-_177324307 0.733 ENSMUST00000108959.2
Gm14412
predicted gene 14412
chrX_+_99042581 0.729 ENSMUST00000036606.7
Stard8
START domain containing 8
chr9_+_15520830 0.725 ENSMUST00000178999.1
Smco4
single-pass membrane protein with coiled-coil domains 4
chr1_-_72212249 0.719 ENSMUST00000048860.7
Mreg
melanoregulin
chr7_-_140955960 0.680 ENSMUST00000081649.8
Ifitm2
interferon induced transmembrane protein 2
chr4_+_122836236 0.675 ENSMUST00000030412.4
ENSMUST00000121870.1
ENSMUST00000097902.4
Ppt1


palmitoyl-protein thioesterase 1


chr4_+_136347286 0.672 ENSMUST00000140052.2
9130020K20Rik
RIKEN cDNA 9130020K20 gene
chr13_-_21453714 0.635 ENSMUST00000032820.7
ENSMUST00000110485.1
Zscan26

zinc finger and SCAN domain containing 26

chr1_+_156838915 0.633 ENSMUST00000111720.1
Angptl1
angiopoietin-like 1
chr6_-_54593139 0.631 ENSMUST00000046520.6
Fkbp14
FK506 binding protein 14
chr15_-_98728120 0.622 ENSMUST00000003445.6
Fkbp11
FK506 binding protein 11
chr12_-_98259416 0.614 ENSMUST00000021390.7
Galc
galactosylceramidase
chr6_+_129180613 0.588 ENSMUST00000032260.5
Clec2d
C-type lectin domain family 2, member d
chr7_-_13054665 0.570 ENSMUST00000182515.1
ENSMUST00000069289.8
Mzf1

myeloid zinc finger 1

chr9_-_124440899 0.554 ENSMUST00000180233.1
Gm20783
predicted gene, 20783
chr10_+_88459569 0.540 ENSMUST00000020252.3
ENSMUST00000125612.1
Sycp3

synaptonemal complex protein 3

chr1_-_57406443 0.532 ENSMUST00000160837.1
ENSMUST00000161780.1
Tyw5

tRNA-yW synthesizing protein 5

chr9_-_103230262 0.492 ENSMUST00000165296.1
ENSMUST00000112645.1
ENSMUST00000166836.1
Trf

Gm20425
transferrin

predicted gene 20425
chr6_+_86195214 0.472 ENSMUST00000032066.9
Tgfa
transforming growth factor alpha
chr2_-_132253227 0.458 ENSMUST00000028817.6
Pcna
proliferating cell nuclear antigen
chr1_+_183388981 0.439 ENSMUST00000097043.5
Taf1a
TATA box binding protein (Tbp)-associated factor, RNA polymerase I, A
chr17_-_32350569 0.426 ENSMUST00000050214.7
Akap8l
A kinase (PRKA) anchor protein 8-like
chr7_+_39517744 0.423 ENSMUST00000108015.1
Zfp619
zinc finger protein 619
chr13_-_74376566 0.417 ENSMUST00000091481.2
Zfp72
zinc finger protein 72
chr9_-_21760275 0.398 ENSMUST00000098942.4
Spc24
SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr7_-_132786914 0.398 ENSMUST00000065371.7
ENSMUST00000106166.1
Fam53b

family with sequence similarity 53, member B

chr11_+_98026918 0.394 ENSMUST00000017548.6
Rpl19
ribosomal protein L19
chr13_-_23562369 0.388 ENSMUST00000105107.1
Hist1h3e
histone cluster 1, H3e
chr8_-_4275886 0.380 ENSMUST00000003029.7
Timm44
translocase of inner mitochondrial membrane 44
chr1_-_93342734 0.377 ENSMUST00000027493.3
Pask
PAS domain containing serine/threonine kinase
chr2_+_177080256 0.365 ENSMUST00000134614.1
ENSMUST00000108968.1
Gm14401

predicted gene 14401

chr12_-_58269162 0.361 ENSMUST00000062254.2
Clec14a
C-type lectin domain family 14, member a
chr17_+_25773769 0.358 ENSMUST00000134108.1
ENSMUST00000002350.4
Narfl

nuclear prelamin A recognition factor-like

chr11_+_80089385 0.354 ENSMUST00000108239.1
ENSMUST00000017694.5
Atad5

ATPase family, AAA domain containing 5

chr9_+_108569885 0.353 ENSMUST00000019183.8
Dalrd3
DALR anticodon binding domain containing 3
chrM_+_10167 0.352 ENSMUST00000082414.1
mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr17_+_46646225 0.345 ENSMUST00000002844.7
ENSMUST00000113429.1
ENSMUST00000113430.1
Mrpl2


mitochondrial ribosomal protein L2


chr6_+_124808885 0.343 ENSMUST00000143040.1
ENSMUST00000052727.4
ENSMUST00000130160.1
Spsb2


splA/ryanodine receptor domain and SOCS box containing 2


chr17_+_26113286 0.339 ENSMUST00000025010.7
Tmem8
transmembrane protein 8 (five membrane-spanning domains)
chr13_-_67332525 0.336 ENSMUST00000168892.1
ENSMUST00000109735.2
Zfp595

zinc finger protein 595

chr11_+_98026695 0.333 ENSMUST00000092425.4
Rpl19
ribosomal protein L19
chr6_-_85451248 0.328 ENSMUST00000113770.1
ENSMUST00000032080.2
Pradc1

protease-associated domain containing 1

chr7_-_80947765 0.327 ENSMUST00000026818.5
ENSMUST00000117383.1
ENSMUST00000119980.1
Sec11a


SEC11 homolog A (S. cerevisiae)


chrX_+_73787002 0.323 ENSMUST00000166518.1
Ssr4
signal sequence receptor, delta
chr11_+_101468164 0.304 ENSMUST00000001347.6
Rnd2
Rho family GTPase 2
chr7_-_132776855 0.291 ENSMUST00000106168.1
Fam53b
family with sequence similarity 53, member B
chr3_-_150073620 0.289 ENSMUST00000057740.5
Rpsa-ps10
ribosomal protein SA, pseudogene 10
chr9_+_73044833 0.285 ENSMUST00000184146.1
ENSMUST00000034722.4
Rab27a

RAB27A, member RAS oncogene family

chrX_-_73786888 0.263 ENSMUST00000052761.8
Idh3g
isocitrate dehydrogenase 3 (NAD+), gamma
chr9_-_54193442 0.255 ENSMUST00000034811.7
Cyp19a1
cytochrome P450, family 19, subfamily a, polypeptide 1
chr2_-_148046896 0.247 ENSMUST00000172928.1
ENSMUST00000047315.3
Foxa2

forkhead box A2

chr7_+_70388305 0.243 ENSMUST00000080024.5
B130024G19Rik
RIKEN cDNA B130024G19 gene
chr4_+_3940747 0.241 ENSMUST00000119403.1
Chchd7
coiled-coil-helix-coiled-coil-helix domain containing 7
chr2_-_112368021 0.234 ENSMUST00000028551.3
Emc4
ER membrane protein complex subunit 4
chr3_-_153944632 0.226 ENSMUST00000072697.6
Acadm
acyl-Coenzyme A dehydrogenase, medium chain
chr1_+_127868773 0.218 ENSMUST00000037649.5
Rab3gap1
RAB3 GTPase activating protein subunit 1
chr11_+_69326252 0.209 ENSMUST00000018614.2
Kcnab3
potassium voltage-gated channel, shaker-related subfamily, beta member 3
chr18_+_37484955 0.202 ENSMUST00000053856.4
Pcdhb17
protocadherin beta 17
chr1_+_15712303 0.192 ENSMUST00000170146.1
Kcnb2
potassium voltage gated channel, Shab-related subfamily, member 2
chr7_-_3720382 0.173 ENSMUST00000078451.6
Pirb
paired Ig-like receptor B
chr5_-_143527977 0.173 ENSMUST00000100489.3
ENSMUST00000080537.7
Rac1

RAS-related C3 botulinum substrate 1

chr16_-_30587537 0.161 ENSMUST00000117363.2
Lsg1
large subunit GTPase 1 homolog (S. cerevisiae)
chr1_+_87404916 0.157 ENSMUST00000173152.1
ENSMUST00000173663.1
Gigyf2

GRB10 interacting GYF protein 2

chr9_-_57467985 0.130 ENSMUST00000046587.6
Scamp5
secretory carrier membrane protein 5
chr11_+_101442298 0.124 ENSMUST00000077856.6
Rpl27
ribosomal protein L27
chr6_-_34177048 0.119 ENSMUST00000019143.8
Slc35b4
solute carrier family 35, member B4
chr9_-_119157055 0.112 ENSMUST00000010795.4
Acaa1b
acetyl-Coenzyme A acyltransferase 1B
chr11_+_74898078 0.103 ENSMUST00000045807.7
Tsr1
TSR1 20S rRNA accumulation
chr4_+_62525369 0.102 ENSMUST00000062145.1
4933430I17Rik
RIKEN cDNA 4933430I17 gene
chr9_+_58582397 0.058 ENSMUST00000176557.1
ENSMUST00000114121.4
ENSMUST00000177064.1
Nptn


neuroplastin


chr5_-_38491948 0.052 ENSMUST00000129099.1
Slc2a9
solute carrier family 2 (facilitated glucose transporter), member 9
chr11_-_120731944 0.052 ENSMUST00000154565.1
ENSMUST00000026148.2
Cbr2

carbonyl reductase 2

chr19_-_11818806 0.049 ENSMUST00000075304.6
Stx3
syntaxin 3
chr11_-_69920892 0.043 ENSMUST00000152589.1
ENSMUST00000108612.1
ENSMUST00000108611.1
Eif5a


eukaryotic translation initiation factor 5A


chr6_+_42286709 0.033 ENSMUST00000163936.1
Clcn1
chloride channel 1
chrX_-_56822308 0.033 ENSMUST00000135542.1
ENSMUST00000114766.1
Mtap7d3

MAP7 domain containing 3

chr17_-_13131791 0.030 ENSMUST00000084966.5
Unc93a
unc-93 homolog A (C. elegans)
chr4_-_45320580 0.029 ENSMUST00000030003.3
Exosc3
exosome component 3
chr7_+_28741968 0.029 ENSMUST00000094632.4
Sars2
seryl-aminoacyl-tRNA synthetase 2
chr10_-_78244602 0.013 ENSMUST00000000384.6
Trappc10
trafficking protein particle complex 10
chr2_+_129100995 0.012 ENSMUST00000103205.4
ENSMUST00000028874.7
Polr1b

polymerase (RNA) I polypeptide B

chrM_+_9870 0.010 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr1_-_24612700 0.010 ENSMUST00000088336.1
Gm10222
predicted gene 10222

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:1901228 regulation of osteoclast proliferation(GO:0090289) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228) negative regulation of bone development(GO:1903011)
0.6 1.9 GO:0051464 positive regulation of cortisol secretion(GO:0051464)
0.5 3.0 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.4 1.2 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) olefin metabolic process(GO:1900673)
0.3 1.6 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.3 1.1 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.2 1.4 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.2 1.0 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.2 0.5 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.1 0.5 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
0.1 0.5 GO:1902990 leading strand elongation(GO:0006272) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.1 0.7 GO:0098734 protein depalmitoylation(GO:0002084) positive regulation of pinocytosis(GO:0048549) macromolecule depalmitoylation(GO:0098734)
0.1 0.6 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 1.7 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1 0.3 GO:0097278 complement-dependent cytotoxicity(GO:0097278)
0.1 0.7 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.1 0.6 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.1 0.2 GO:0045014 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594)
0.1 0.2 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
0.1 0.5 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.1 0.3 GO:0035937 androgen catabolic process(GO:0006710) estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) testosterone biosynthetic process(GO:0061370) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.1 0.4 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.1 0.4 GO:0032364 oxygen homeostasis(GO:0032364)
0.0 0.4 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.4 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.4 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.3 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.5 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.7 GO:0032402 melanosome transport(GO:0032402)
0.0 0.7 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.2 GO:0032627 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 1.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.3 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.3 GO:0006465 signal peptide processing(GO:0006465)
0.0 1.1 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.1 GO:0006116 NADH oxidation(GO:0006116)
0.0 0.7 GO:0035411 catenin import into nucleus(GO:0035411)
0.0 1.2 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0000802 transverse filament(GO:0000802)
0.2 0.5 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 0.4 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 0.4 GO:0097361 CIA complex(GO:0097361)
0.1 1.1 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.4 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.3 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 0.5 GO:0005785 signal recognition particle receptor complex(GO:0005785) dense body(GO:0097433)
0.1 0.3 GO:0033093 multivesicular body membrane(GO:0032585) Weibel-Palade body(GO:0033093)
0.0 0.3 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.8 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.2 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 0.7 GO:0048786 presynaptic active zone(GO:0048786)
0.0 6.7 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.9 GO:0031526 brush border membrane(GO:0031526)
0.0 2.2 GO:0001650 fibrillar center(GO:0001650)
0.0 0.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0004966 galanin receptor activity(GO:0004966)
0.3 2.9 GO:0036122 BMP binding(GO:0036122)
0.2 1.2 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.2 1.6 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.2 2.2 GO:0008430 selenium binding(GO:0008430)
0.2 0.5 GO:0032139 DNA polymerase processivity factor activity(GO:0030337) dinucleotide insertion or deletion binding(GO:0032139)
0.1 0.7 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 1.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 3.0 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.7 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 0.3 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.6 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 0.5 GO:0015091 signal recognition particle binding(GO:0005047) ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 0.7 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 1.0 GO:0070403 NAD+ binding(GO:0070403)
0.1 1.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.4 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.2 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.1 0.3 GO:0070330 aromatase activity(GO:0070330)
0.0 1.4 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 1.1 GO:0005109 frizzled binding(GO:0005109)
0.0 0.7 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.0 0.4 GO:0034237 lamin binding(GO:0005521) protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.2 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 1.2 GO:0004540 ribonuclease activity(GO:0004540)
0.0 0.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.3 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 PID_BMP_PATHWAY BMP receptor signaling
0.0 0.5 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 2.3 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.9 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 2.1 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.5 PID_BARD1_PATHWAY BARD1 signaling events
0.0 1.0 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 0.5 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 0.5 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 1.4 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.0 0.3 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 1.9 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.6 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.5 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.2 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.3 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.6 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.2 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.2 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.6 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.4 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels