Motif ID: Tfap2c

Z-value: 0.789


Transcription factors associated with Tfap2c:

Gene SymbolEntrez IDGene Name
Tfap2c ENSMUSG00000028640.5 Tfap2c

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tfap2cmm10_v2_chr2_+_172550761_172550782-0.516.1e-04Click!


Activity profile for motif Tfap2c.

activity profile for motif Tfap2c


Sorted Z-values histogram for motif Tfap2c

Sorted Z-values for motif Tfap2c



Network of associatons between targets according to the STRING database.



First level regulatory network of Tfap2c

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_+_89909775 3.052 ENSMUST00000034912.4
ENSMUST00000034909.4
Rasgrf1

RAS protein-specific guanine nucleotide-releasing factor 1

chr6_+_4505493 2.962 ENSMUST00000031668.8
Col1a2
collagen, type I, alpha 2
chr5_-_131307848 2.705 ENSMUST00000086023.5
Wbscr17
Williams-Beuren syndrome chromosome region 17 homolog (human)
chr2_+_76406529 2.614 ENSMUST00000111929.1
ENSMUST00000077972.4
ENSMUST00000111930.2
Osbpl6


oxysterol binding protein-like 6


chr18_-_61911783 2.382 ENSMUST00000049378.8
ENSMUST00000166783.1
Ablim3

actin binding LIM protein family, member 3

chr8_+_70493156 2.303 ENSMUST00000008032.7
Crlf1
cytokine receptor-like factor 1
chr1_-_184883218 2.221 ENSMUST00000048308.5
C130074G19Rik
RIKEN cDNA C130074G19 gene
chr4_+_152338887 2.183 ENSMUST00000005175.4
Chd5
chromodomain helicase DNA binding protein 5
chr7_+_99535652 2.087 ENSMUST00000032995.8
ENSMUST00000162404.1
Arrb1

arrestin, beta 1

chr4_+_152338619 1.937 ENSMUST00000030775.5
ENSMUST00000164662.1
Chd5

chromodomain helicase DNA binding protein 5

chr7_-_29518566 1.933 ENSMUST00000181975.1
Sipa1l3
signal-induced proliferation-associated 1 like 3
chr2_+_91945703 1.924 ENSMUST00000178895.1
Gm9821
predicted gene 9821
chr10_+_13966268 1.809 ENSMUST00000015645.4
Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr9_+_45430293 1.808 ENSMUST00000034592.8
Dscaml1
Down syndrome cell adhesion molecule like 1
chr14_+_119138415 1.793 ENSMUST00000065904.3
Hs6st3
heparan sulfate 6-O-sulfotransferase 3
chr9_+_58823512 1.702 ENSMUST00000034889.8
Hcn4
hyperpolarization-activated, cyclic nucleotide-gated K+ 4
chr11_+_67455339 1.682 ENSMUST00000108681.1
Gas7
growth arrest specific 7
chr11_-_106715251 1.650 ENSMUST00000080853.4
ENSMUST00000183610.1
ENSMUST00000103069.3
ENSMUST00000106796.2
Pecam1



platelet/endothelial cell adhesion molecule 1



chr4_-_116464151 1.590 ENSMUST00000106486.1
ENSMUST00000106485.1
Mast2

microtubule associated serine/threonine kinase 2

chr1_-_75264195 1.582 ENSMUST00000027404.5
Ptprn
protein tyrosine phosphatase, receptor type, N
chr5_-_35679416 1.575 ENSMUST00000114233.2
Htra3
HtrA serine peptidase 3
chr6_+_4504814 1.573 ENSMUST00000141483.1
Col1a2
collagen, type I, alpha 2
chr4_-_22488296 1.572 ENSMUST00000178174.1
Pou3f2
POU domain, class 3, transcription factor 2
chr15_+_100761741 1.482 ENSMUST00000023776.6
Slc4a8
solute carrier family 4 (anion exchanger), member 8
chr4_+_124657646 1.478 ENSMUST00000053491.7
Pou3f1
POU domain, class 3, transcription factor 1
chr11_-_120047070 1.476 ENSMUST00000064307.3
Aatk
apoptosis-associated tyrosine kinase
chr6_+_38663061 1.470 ENSMUST00000114874.3
Clec2l
C-type lectin domain family 2, member L
chr12_-_76709997 1.463 ENSMUST00000166101.1
Sptb
spectrin beta, erythrocytic
chr3_-_88503187 1.430 ENSMUST00000120377.1
Lmna
lamin A
chr15_+_80287234 1.422 ENSMUST00000160424.1
Cacna1i
calcium channel, voltage-dependent, alpha 1I subunit
chrX_+_94234594 1.388 ENSMUST00000153900.1
Klhl15
kelch-like 15
chr16_+_35154870 1.379 ENSMUST00000114913.1
Adcy5
adenylate cyclase 5
chr3_-_88503331 1.363 ENSMUST00000029699.6
Lmna
lamin A
chr9_-_29411736 1.328 ENSMUST00000115236.1
Ntm
neurotrimin
chr11_-_59964936 1.314 ENSMUST00000062405.7
Rasd1
RAS, dexamethasone-induced 1
chr2_-_146511899 1.306 ENSMUST00000131824.1
Ralgapa2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr6_-_28831747 1.270 ENSMUST00000062304.5
Lrrc4
leucine rich repeat containing 4
chr9_-_29412204 1.245 ENSMUST00000115237.1
Ntm
neurotrimin
chr1_+_75479529 1.186 ENSMUST00000113575.2
ENSMUST00000148980.1
ENSMUST00000050899.6
Tmem198


transmembrane protein 198


chr2_+_156421083 1.155 ENSMUST00000125153.2
ENSMUST00000103136.1
ENSMUST00000109577.2
Epb4.1l1


erythrocyte protein band 4.1-like 1


chr17_+_86167777 1.155 ENSMUST00000097275.2
Prkce
protein kinase C, epsilon
chr10_-_13868779 1.127 ENSMUST00000105534.3
Aig1
androgen-induced 1
chr3_-_108086590 1.123 ENSMUST00000102638.1
ENSMUST00000102637.1
Ampd2

adenosine monophosphate deaminase 2

chr7_+_25627604 1.116 ENSMUST00000076034.6
B3gnt8
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
chr8_-_105966038 1.108 ENSMUST00000116429.2
ENSMUST00000034370.9
Slc12a4

solute carrier family 12, member 4

chr3_-_89089955 1.085 ENSMUST00000166687.1
Rusc1
RUN and SH3 domain containing 1
chr12_-_81333129 1.077 ENSMUST00000085238.6
ENSMUST00000182208.1
Slc8a3

solute carrier family 8 (sodium/calcium exchanger), member 3

chr2_+_156420837 1.036 ENSMUST00000103137.3
Epb4.1l1
erythrocyte protein band 4.1-like 1
chr6_+_118066356 1.035 ENSMUST00000164960.1
Rasgef1a
RasGEF domain family, member 1A
chr8_+_25518783 1.028 ENSMUST00000084027.5
ENSMUST00000117179.2
Fgfr1

fibroblast growth factor receptor 1

chr8_+_25518757 1.013 ENSMUST00000178276.1
ENSMUST00000179592.1
Fgfr1

fibroblast growth factor receptor 1

chr1_-_75479271 1.012 ENSMUST00000079205.7
ENSMUST00000094818.2
Chpf

chondroitin polymerizing factor

chr2_-_32353247 1.011 ENSMUST00000078352.5
ENSMUST00000113352.2
ENSMUST00000113365.1
Dnm1


dynamin 1


chrX_-_142306170 1.004 ENSMUST00000134825.2
Kcne1l
potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene
chr11_+_69088490 1.002 ENSMUST00000021273.6
ENSMUST00000117780.1
Vamp2

vesicle-associated membrane protein 2

chr17_+_29660710 0.989 ENSMUST00000130423.1
Cmtr1
cap methyltransferase 1
chr7_-_31126945 0.986 ENSMUST00000098548.4
Scn1b
sodium channel, voltage-gated, type I, beta
chr2_+_156421048 0.959 ENSMUST00000109574.1
Epb4.1l1
erythrocyte protein band 4.1-like 1
chr17_+_28575718 0.936 ENSMUST00000080780.6
Lhfpl5
lipoma HMGIC fusion partner-like 5
chr8_+_122282117 0.885 ENSMUST00000054052.8
Zfpm1
zinc finger protein, multitype 1
chr3_-_9610074 0.871 ENSMUST00000041124.7
Zfp704
zinc finger protein 704
chr9_+_58554799 0.868 ENSMUST00000098676.2
Gm10657
predicted gene 10657
chr7_+_80860909 0.838 ENSMUST00000132163.1
ENSMUST00000147125.1
Zscan2

zinc finger and SCAN domain containing 2

chr8_-_34965631 0.829 ENSMUST00000033929.4
Tnks
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr13_-_23622502 0.794 ENSMUST00000062045.2
Hist1h1e
histone cluster 1, H1e
chr9_+_109931458 0.793 ENSMUST00000072772.5
ENSMUST00000035055.8
Map4

microtubule-associated protein 4

chr7_+_19004047 0.791 ENSMUST00000053713.3
Irf2bp1
interferon regulatory factor 2 binding protein 1
chr1_-_64121389 0.783 ENSMUST00000055001.3
Klf7
Kruppel-like factor 7 (ubiquitous)
chrX_+_163908982 0.782 ENSMUST00000069041.8
Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr7_-_4789541 0.766 ENSMUST00000168578.1
Tmem238
transmembrane protein 238
chr11_+_102430315 0.758 ENSMUST00000049460.4
ENSMUST00000129997.1
Grn

granulin

chr3_-_58692391 0.728 ENSMUST00000070368.7
Siah2
seven in absentia 2
chr11_-_116110211 0.724 ENSMUST00000106441.1
ENSMUST00000021120.5
Trim47

tripartite motif-containing 47

chr7_-_138846202 0.716 ENSMUST00000118810.1
ENSMUST00000075667.4
ENSMUST00000119664.1
Mapk1ip1


mitogen-activated protein kinase 1 interacting protein 1


chr15_-_76351008 0.706 ENSMUST00000023211.9
Sharpin
SHANK-associated RH domain interacting protein
chr8_-_83699095 0.701 ENSMUST00000005616.8
Pkn1
protein kinase N1
chr11_+_85832551 0.689 ENSMUST00000000095.6
Tbx2
T-box 2
chr9_-_99436687 0.685 ENSMUST00000035045.8
Mras
muscle and microspikes RAS
chr4_+_129136948 0.678 ENSMUST00000102600.3
Fndc5
fibronectin type III domain containing 5
chr7_-_25237849 0.662 ENSMUST00000071739.5
ENSMUST00000108411.1
Gsk3a

glycogen synthase kinase 3 alpha

chr4_+_124885799 0.659 ENSMUST00000149146.1
Epha10
Eph receptor A10
chr2_+_164460945 0.618 ENSMUST00000072452.4
Sys1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr6_-_12749193 0.613 ENSMUST00000046121.6
ENSMUST00000172356.1
Thsd7a

thrombospondin, type I, domain containing 7A

chr8_+_105605220 0.604 ENSMUST00000043531.8
Fam65a
family with sequence similarity 65, member A
chr19_-_45998479 0.601 ENSMUST00000045396.7
9130011E15Rik
RIKEN cDNA 9130011E15 gene
chr2_-_154408078 0.586 ENSMUST00000028991.6
ENSMUST00000109728.1
Snta1

syntrophin, acidic 1

chr9_+_108002501 0.583 ENSMUST00000035214.4
ENSMUST00000175874.1
Ip6k1

inositol hexaphosphate kinase 1

chr6_-_125313844 0.578 ENSMUST00000032489.7
Ltbr
lymphotoxin B receptor
chrX_+_53607918 0.567 ENSMUST00000114827.1
Cxx1c
CAAX box 1C
chr17_+_29660595 0.560 ENSMUST00000024816.6
Cmtr1
cap methyltransferase 1
chr9_-_121995962 0.558 ENSMUST00000084743.5
Pomgnt2
protein O-linked mannose beta 1,4-N-acetylglucosaminyltransferase 2
chr19_-_7341433 0.534 ENSMUST00000165965.1
ENSMUST00000051711.9
ENSMUST00000169541.1
ENSMUST00000165989.1
Mark2



MAP/microtubule affinity-regulating kinase 2



chrX_-_73824938 0.527 ENSMUST00000114438.2
ENSMUST00000002080.5
Pdzd4

PDZ domain containing 4

chr14_-_24245913 0.527 ENSMUST00000073687.6
ENSMUST00000090398.4
Dlg5

discs, large homolog 5 (Drosophila)

chrX_+_53607987 0.525 ENSMUST00000063384.3
ENSMUST00000169626.1
Cxx1c

CAAX box 1C

chr2_-_167062981 0.522 ENSMUST00000048988.7
Znfx1
zinc finger, NFX1-type containing 1
chr2_-_167062607 0.517 ENSMUST00000128676.1
Znfx1
zinc finger, NFX1-type containing 1
chr2_+_130906461 0.515 ENSMUST00000028781.8
Atrn
attractin
chr9_-_99436749 0.512 ENSMUST00000122384.1
Mras
muscle and microspikes RAS
chr1_+_59912972 0.511 ENSMUST00000036540.5
Fam117b
family with sequence similarity 117, member B
chr7_-_27674516 0.508 ENSMUST00000036453.7
ENSMUST00000108341.1
Map3k10

mitogen-activated protein kinase kinase kinase 10

chr9_+_109931774 0.505 ENSMUST00000169851.2
Map4
microtubule-associated protein 4
chr6_+_88198656 0.501 ENSMUST00000015197.7
Gata2
GATA binding protein 2
chr9_-_58555129 0.491 ENSMUST00000165365.1
Cd276
CD276 antigen
chr17_-_46752170 0.488 ENSMUST00000121671.1
ENSMUST00000059844.6
Cnpy3

canopy 3 homolog (zebrafish)

chr7_-_43489967 0.487 ENSMUST00000107974.1
Iglon5
IgLON family member 5
chr7_+_24903011 0.482 ENSMUST00000047873.9
ENSMUST00000098683.4
Arhgef1

Rho guanine nucleotide exchange factor (GEF) 1

chr4_-_56990332 0.476 ENSMUST00000053681.5
Frrs1l
ferric-chelate reductase 1 like
chr7_+_24907618 0.451 ENSMUST00000151121.1
Arhgef1
Rho guanine nucleotide exchange factor (GEF) 1
chr19_+_5068077 0.445 ENSMUST00000070630.6
Cd248
CD248 antigen, endosialin
chr11_+_75193783 0.443 ENSMUST00000102514.3
Rtn4rl1
reticulon 4 receptor-like 1
chr4_-_129614254 0.439 ENSMUST00000106037.2
ENSMUST00000179209.1
Dcdc2b

doublecortin domain containing 2b

chr16_+_17070127 0.438 ENSMUST00000115729.1
Ypel1
yippee-like 1 (Drosophila)
chr11_-_96065350 0.435 ENSMUST00000100528.4
Ube2z
ubiquitin-conjugating enzyme E2Z (putative)
chrX_+_163909132 0.433 ENSMUST00000033734.7
ENSMUST00000112294.2
Ap1s2

adaptor-related protein complex 1, sigma 2 subunit

chr18_+_74216118 0.432 ENSMUST00000025444.6
Cxxc1
CXXC finger 1 (PHD domain)
chr13_+_73467197 0.432 ENSMUST00000022099.8
Lpcat1
lysophosphatidylcholine acyltransferase 1
chr7_+_25282784 0.426 ENSMUST00000165239.1
Cic
capicua homolog (Drosophila)
chr7_+_24902912 0.423 ENSMUST00000117796.1
Arhgef1
Rho guanine nucleotide exchange factor (GEF) 1
chr15_+_54571358 0.417 ENSMUST00000025356.2
Mal2
mal, T cell differentiation protein 2
chr14_-_70153811 0.417 ENSMUST00000035612.5
Ccar2
cell cycle activator and apoptosis regulator 2
chr10_+_127380799 0.413 ENSMUST00000111628.2
R3hdm2
R3H domain containing 2
chr7_+_127777095 0.406 ENSMUST00000144406.1
Setd1a
SET domain containing 1A
chr11_+_77763246 0.403 ENSMUST00000108375.2
Myo18a
myosin XVIIIA
chr11_-_5741141 0.403 ENSMUST00000140922.1
ENSMUST00000093362.5
Urgcp

upregulator of cell proliferation

chr5_-_71095765 0.402 ENSMUST00000000572.5
Gabra2
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 2
chr11_-_65162904 0.399 ENSMUST00000093002.5
ENSMUST00000047463.8
Arhgap44

Rho GTPase activating protein 44

chr4_-_142084221 0.397 ENSMUST00000036572.3
Tmem51
transmembrane protein 51
chr9_-_107231816 0.395 ENSMUST00000044532.4
Dock3
dedicator of cyto-kinesis 3
chr5_+_30588078 0.394 ENSMUST00000066295.2
Kcnk3
potassium channel, subfamily K, member 3
chr19_+_16132812 0.388 ENSMUST00000025541.5
Gnaq
guanine nucleotide binding protein, alpha q polypeptide
chr1_-_6215292 0.386 ENSMUST00000097832.1
4732440D04Rik
RIKEN cDNA 4732440D04 gene
chr7_+_16816299 0.384 ENSMUST00000108495.2
Strn4
striatin, calmodulin binding protein 4
chr5_-_122989086 0.383 ENSMUST00000046073.9
Kdm2b
lysine (K)-specific demethylase 2B
chr4_-_154636831 0.379 ENSMUST00000030902.6
ENSMUST00000105637.1
ENSMUST00000070313.7
ENSMUST00000105636.1
ENSMUST00000105638.2
ENSMUST00000097759.2
ENSMUST00000124771.1
Prdm16






PR domain containing 16






chr5_-_92435114 0.366 ENSMUST00000135112.1
Nup54
nucleoporin 54
chr10_+_88379217 0.363 ENSMUST00000130301.1
ENSMUST00000020251.8
Gnptab

N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits

chr9_+_21424984 0.355 ENSMUST00000172482.1
ENSMUST00000174050.1
Dnm2

dynamin 2

chr4_-_155056784 0.352 ENSMUST00000131173.2
Plch2
phospholipase C, eta 2
chr15_+_76351288 0.349 ENSMUST00000161527.1
ENSMUST00000160853.1
Maf1

MAF1 homolog (S. cerevisiae)

chr7_-_127449109 0.348 ENSMUST00000053392.4
Zfp689
zinc finger protein 689
chr17_-_46556158 0.343 ENSMUST00000015749.5
Srf
serum response factor
chr12_+_110601439 0.341 ENSMUST00000018851.7
Dync1h1
dynein cytoplasmic 1 heavy chain 1
chr16_-_18289199 0.336 ENSMUST00000009321.4
ENSMUST00000115633.1
Dgcr8

DiGeorge syndrome critical region gene 8

chr8_-_85067982 0.334 ENSMUST00000177563.1
Gm5741
predicted gene 5741
chr15_+_98634743 0.333 ENSMUST00000003442.7
Cacnb3
calcium channel, voltage-dependent, beta 3 subunit
chr8_+_35587780 0.324 ENSMUST00000037666.5
Mfhas1
malignant fibrous histiocytoma amplified sequence 1
chr13_+_54371340 0.320 ENSMUST00000026985.8
Cplx2
complexin 2
chr14_+_20707548 0.319 ENSMUST00000022358.7
Zswim8
zinc finger SWIM-type containing 8
chr3_+_118562129 0.318 ENSMUST00000039177.7
Dpyd
dihydropyrimidine dehydrogenase
chr14_+_31251454 0.315 ENSMUST00000022458.4
Bap1
Brca1 associated protein 1
chr11_+_19924354 0.314 ENSMUST00000093299.6
Spred2
sprouty-related, EVH1 domain containing 2
chr19_+_6341121 0.313 ENSMUST00000025897.6
ENSMUST00000130382.1
Map4k2

mitogen-activated protein kinase kinase kinase kinase 2

chr5_-_122989260 0.312 ENSMUST00000118027.1
Kdm2b
lysine (K)-specific demethylase 2B
chr2_+_32609043 0.307 ENSMUST00000128811.1
St6galnac6
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr11_-_80377975 0.305 ENSMUST00000179332.1
ENSMUST00000103225.4
ENSMUST00000134274.1
5730455P16Rik


RIKEN cDNA 5730455P16 gene


chr1_-_63114255 0.304 ENSMUST00000153992.1
ENSMUST00000165066.1
ENSMUST00000172416.1
ENSMUST00000137511.1
Ino80d



INO80 complex subunit D



chr7_-_105787544 0.301 ENSMUST00000078482.5
ENSMUST00000154659.1
Dchs1

dachsous 1 (Drosophila)

chr7_-_67372846 0.296 ENSMUST00000156690.1
ENSMUST00000107476.1
ENSMUST00000076325.5
ENSMUST00000032776.8
ENSMUST00000133074.1
Mef2a




myocyte enhancer factor 2A




chr12_+_102283036 0.292 ENSMUST00000056950.7
Rin3
Ras and Rab interactor 3
chr19_+_10041548 0.291 ENSMUST00000115995.2
Fads3
fatty acid desaturase 3
chr17_+_27565112 0.282 ENSMUST00000097361.1
C130040N14Rik
RIKEN cDNA C130040N14 gene
chr12_-_99393010 0.281 ENSMUST00000177451.1
Foxn3
forkhead box N3
chr19_+_46573362 0.275 ENSMUST00000026011.6
Sfxn2
sideroflexin 2
chr11_+_74830920 0.270 ENSMUST00000000291.2
Mnt
max binding protein
chr7_+_107370728 0.267 ENSMUST00000137663.1
ENSMUST00000073459.5
Syt9

synaptotagmin IX

chr1_+_165461037 0.266 ENSMUST00000027853.5
Mpc2
mitochondrial pyruvate carrier 2
chr6_+_21985903 0.266 ENSMUST00000137437.1
ENSMUST00000115383.2
Cped1

cadherin-like and PC-esterase domain containing 1

chr18_-_60848911 0.266 ENSMUST00000177172.1
ENSMUST00000175934.1
ENSMUST00000176630.1
Tcof1


Treacher Collins Franceschetti syndrome 1, homolog


chr5_+_117357274 0.264 ENSMUST00000031309.9
Wsb2
WD repeat and SOCS box-containing 2
chr2_-_29869785 0.264 ENSMUST00000047607.1
2600006K01Rik
RIKEN cDNA 2600006K01 gene
chr9_+_21424901 0.264 ENSMUST00000165766.2
ENSMUST00000173397.1
ENSMUST00000072362.7
ENSMUST00000091087.6
ENSMUST00000115404.4
Dnm2




dynamin 2




chr16_+_17070220 0.259 ENSMUST00000141959.1
Ypel1
yippee-like 1 (Drosophila)
chr11_+_70970181 0.255 ENSMUST00000018593.3
Rpain
RPA interacting protein
chr15_+_100469034 0.253 ENSMUST00000037001.8
Letmd1
LETM1 domain containing 1
chr2_+_35622010 0.243 ENSMUST00000091010.5
Dab2ip
disabled 2 interacting protein
chr7_+_141194148 0.241 ENSMUST00000084446.2
ENSMUST00000070458.4
Lrrc56

leucine rich repeat containing 56

chr7_+_25221417 0.241 ENSMUST00000055604.4
Zfp526
zinc finger protein 526
chr13_-_9764865 0.240 ENSMUST00000128658.1
Zmynd11
zinc finger, MYND domain containing 11
chr2_-_34913976 0.234 ENSMUST00000028232.3
Phf19
PHD finger protein 19
chr5_+_129908538 0.233 ENSMUST00000178355.1
Nupr1l
nuclear protein transcriptional regulator 1 like
chr8_-_123515333 0.229 ENSMUST00000177240.1
Dbndd1
dysbindin (dystrobrevin binding protein 1) domain containing 1
chr5_-_136565432 0.228 ENSMUST00000176172.1
Cux1
cut-like homeobox 1
chr17_+_26933070 0.220 ENSMUST00000073724.5
Phf1
PHD finger protein 1
chr4_+_119539716 0.216 ENSMUST00000137560.1
Foxj3
forkhead box J3
chr14_+_79451791 0.216 ENSMUST00000100359.1
Zbtbd6
kelch repeat and BTB (POZ) domain containing 6
chr11_-_78183551 0.210 ENSMUST00000102483.4
Rpl23a
ribosomal protein L23A
chr2_+_35622160 0.208 ENSMUST00000112992.2
Dab2ip
disabled 2 interacting protein
chr9_-_108305941 0.208 ENSMUST00000044725.7
Tcta
T cell leukemia translocation altered gene
chr11_+_69395647 0.203 ENSMUST00000144531.1
Lsmd1
LSM domain containing 1
chr5_-_122900267 0.202 ENSMUST00000031435.7
Kdm2b
lysine (K)-specific demethylase 2B
chr9_+_108296853 0.198 ENSMUST00000035230.5
Amt
aminomethyltransferase
chr10_+_127380591 0.197 ENSMUST00000166820.1
R3hdm2
R3H domain containing 2
chr3_-_61365951 0.196 ENSMUST00000066298.2
B430305J03Rik
RIKEN cDNA B430305J03 gene
chr10_-_67548944 0.192 ENSMUST00000075686.4
Ado
2-aminoethanethiol (cysteamine) dioxygenase
chr7_+_127777376 0.187 ENSMUST00000126761.1
ENSMUST00000047157.6
Setd1a

SET domain containing 1A

chr4_-_120287349 0.185 ENSMUST00000102656.3
Foxo6
forkhead box O6
chr15_-_98871175 0.182 ENSMUST00000178486.2
ENSMUST00000023741.9
Kmt2d

lysine (K)-specific methyltransferase 2D

chr11_+_102435285 0.180 ENSMUST00000125819.2
ENSMUST00000177428.1
Grn

granulin

chr3_+_103914099 0.180 ENSMUST00000051139.6
ENSMUST00000068879.4
Rsbn1

rosbin, round spermatid basic protein 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0021837 motogenic signaling involved in postnatal olfactory bulb interneuron migration(GO:0021837) positive regulation of mitotic cell cycle DNA replication(GO:1903465)
0.6 4.1 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.6 2.8 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.5 1.5 GO:0097309 cap1 mRNA methylation(GO:0097309)
0.5 1.0 GO:0086047 membrane depolarization during Purkinje myocyte cell action potential(GO:0086047)
0.4 1.7 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.4 1.7 GO:0050904 diapedesis(GO:0050904)
0.4 2.3 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.4 4.9 GO:0043589 skin morphogenesis(GO:0043589)
0.3 2.1 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393) follicle-stimulating hormone signaling pathway(GO:0042699)
0.3 1.0 GO:0002447 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
0.3 1.8 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.3 0.9 GO:0042097 tricuspid valve formation(GO:0003195) interleukin-4 biosynthetic process(GO:0042097) regulation of interleukin-4 biosynthetic process(GO:0045402) transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.3 1.2 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.3 0.8 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.3 1.4 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.3 1.9 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.3 1.3 GO:0060178 regulation of exocyst localization(GO:0060178)
0.2 1.4 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.2 0.7 GO:0007521 muscle cell fate determination(GO:0007521) mammary placode formation(GO:0060596)
0.2 1.8 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.2 1.1 GO:1990034 calcium ion export from cell(GO:1990034)
0.2 3.5 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.2 1.0 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.2 1.6 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.2 0.9 GO:0021993 initiation of neural tube closure(GO:0021993)
0.2 0.5 GO:0030222 eosinophil differentiation(GO:0030222)
0.2 0.7 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.2 1.1 GO:0032264 IMP salvage(GO:0032264)
0.2 1.6 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 1.0 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.1 0.4 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.1 0.7 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 1.5 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 0.9 GO:0035188 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1 1.1 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.1 1.6 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 0.5 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.1 0.4 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.1 0.3 GO:0072382 minus-end-directed vesicle transport along microtubule(GO:0072382)
0.1 0.8 GO:0016584 nucleosome positioning(GO:0016584)
0.1 1.0 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.4 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.1 0.3 GO:0046104 thymidine metabolic process(GO:0046104)
0.1 0.5 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.7 GO:2000348 protein linear polyubiquitination(GO:0097039) regulation of CD40 signaling pathway(GO:2000348)
0.1 0.4 GO:1903028 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.1 0.2 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.1 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.1 0.3 GO:0070375 ERK5 cascade(GO:0070375)
0.1 0.4 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 0.5 GO:0036324 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144) vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.1 0.3 GO:0003192 mitral valve formation(GO:0003192) condensed mesenchymal cell proliferation(GO:0072137)
0.1 1.3 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.1 0.4 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.3 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 0.5 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 0.9 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.1 1.7 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.1 0.3 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.1 0.6 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 0.6 GO:0000042 protein targeting to Golgi(GO:0000042)
0.1 1.3 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.1 0.6 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 0.6 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.1 0.6 GO:0006020 inositol metabolic process(GO:0006020)
0.1 0.2 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.3 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 1.6 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.2 GO:0035617 stress granule disassembly(GO:0035617)
0.0 1.0 GO:0048535 lymph node development(GO:0048535)
0.0 0.3 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.2 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.5 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.2 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 1.5 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.0 0.4 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.3 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577)
0.0 0.3 GO:0014029 neural crest formation(GO:0014029)
0.0 1.9 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.0 0.1 GO:0045358 negative regulation of interferon-beta biosynthetic process(GO:0045358)
0.0 0.1 GO:0042713 positive regulation of norepinephrine secretion(GO:0010701) sperm ejaculation(GO:0042713) negative regulation of gastric acid secretion(GO:0060455)
0.0 0.4 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0009957 epidermal cell fate specification(GO:0009957)
0.0 2.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 1.6 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.2 GO:0044539 long-chain fatty acid import(GO:0044539)
0.0 1.2 GO:0060612 adipose tissue development(GO:0060612)
0.0 1.1 GO:0006023 aminoglycan biosynthetic process(GO:0006023)
0.0 0.1 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.3 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.3 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.3 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 1.5 GO:0051453 regulation of intracellular pH(GO:0051453)
0.0 0.2 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.1 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.9 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.1 GO:0015822 ornithine transport(GO:0015822)
0.0 0.6 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.0 0.0 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.2 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.5 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 1.4 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.4 GO:1900449 regulation of glutamate receptor signaling pathway(GO:1900449)
0.0 1.7 GO:0030041 actin filament polymerization(GO:0030041)
0.0 1.6 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.0 0.6 GO:0048286 lung alveolus development(GO:0048286)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.5 GO:0005584 collagen type I trimer(GO:0005584)
0.8 2.3 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.6 1.7 GO:0098855 HCN channel complex(GO:0098855)
0.4 2.8 GO:0005638 lamin filament(GO:0005638)
0.3 1.3 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.3 1.7 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.3 1.9 GO:0061689 tricellular tight junction(GO:0061689)
0.2 1.5 GO:0008091 spectrin(GO:0008091)
0.2 0.7 GO:0071797 LUBAC complex(GO:0071797)
0.2 4.1 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 3.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 2.1 GO:0031143 pseudopodium(GO:0031143)
0.1 0.5 GO:1990032 parallel fiber(GO:1990032)
0.1 0.3 GO:1903095 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.1 2.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.9 GO:0032426 stereocilium tip(GO:0032426)
0.1 1.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 1.0 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 1.0 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 1.0 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 1.0 GO:0043196 varicosity(GO:0043196)
0.1 0.5 GO:0097427 microtubule bundle(GO:0097427)
0.1 0.4 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.8 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 1.5 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.3 GO:0002177 manchette(GO:0002177)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.6 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.4 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 1.5 GO:0044295 axonal growth cone(GO:0044295)
0.0 3.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.8 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.3 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.7 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.9 GO:0031519 PcG protein complex(GO:0031519)
0.0 1.3 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.7 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 1.8 GO:0005884 actin filament(GO:0005884)
0.0 1.6 GO:0042641 actomyosin(GO:0042641)
0.0 0.3 GO:0060077 inhibitory synapse(GO:0060077)
0.0 1.7 GO:0043679 axon terminus(GO:0043679)
0.0 1.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.2 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.5 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.1 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.7 2.1 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.4 1.8 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.4 1.7 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.4 1.5 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.4 1.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.4 1.5 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.3 1.0 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.3 2.3 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.3 4.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.3 1.2 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.2 0.7 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.2 1.4 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.2 2.0 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 1.6 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.2 1.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 1.1 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.6 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.1 0.4 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1 1.0 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.8 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.4 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 0.5 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 1.0 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.1 1.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.6 GO:1990188 euchromatin binding(GO:1990188)
0.1 2.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.4 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 0.3 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 0.8 GO:0032564 dATP binding(GO:0032564)
0.1 1.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.4 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 1.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.3 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.1 0.3 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1 0.4 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.1 1.5 GO:0030506 ankyrin binding(GO:0030506)
0.1 0.3 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.5 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.2 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.1 0.3 GO:0002054 nucleobase binding(GO:0002054)
0.1 0.9 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 1.7 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 3.1 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.9 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.0 0.8 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158)
0.0 1.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 1.2 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.5 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.3 GO:0070878 primary miRNA binding(GO:0070878)
0.0 0.6 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 1.6 GO:0030507 spectrin binding(GO:0030507)
0.0 0.2 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.3 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.6 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 1.0 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 4.9 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.2 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.7 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 2.6 GO:0019902 phosphatase binding(GO:0019902)
0.0 0.9 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 5.6 GO:0003779 actin binding(GO:0003779)
0.0 1.3 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.0 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.0 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.4 GO:0046332 SMAD binding(GO:0046332)
0.0 0.2 GO:0033549 MAP kinase phosphatase activity(GO:0033549)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.1 4.5 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 6.2 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.1 3.3 PID_RAS_PATHWAY Regulation of Ras family activation
0.1 2.0 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.0 2.8 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 1.4 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.6 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.9 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.7 SIG_IL4RECEPTOR_IN_B_LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 1.0 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 0.5 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 1.9 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 1.3 ST_INTEGRIN_SIGNALING_PATHWAY Integrin Signaling Pathway
0.0 0.2 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.6 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.5 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.9 PID_CMYB_PATHWAY C-MYB transcription factor network
0.0 1.2 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.6 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.2 2.0 REACTOME_SIGNALING_BY_ACTIVATED_POINT_MUTANTS_OF_FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.1 4.9 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 2.4 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.7 REACTOME_PECAM1_INTERACTIONS Genes involved in PECAM1 interactions
0.1 1.4 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 2.9 REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 3.8 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.1 1.0 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 1.1 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 1.1 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.1 2.4 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.1 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.1 3.6 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 0.4 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 0.5 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 1.0 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.4 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.8 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.2 REACTOME_DAG_AND_IP3_SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.4 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.0 1.8 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.0 2.7 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.4 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.0 0.6 REACTOME_SIGNALING_BY_FGFR1_MUTANTS Genes involved in Signaling by FGFR1 mutants
0.0 1.6 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.0 0.5 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.0 1.8 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.4 REACTOME_G_ALPHA1213_SIGNALLING_EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.3 REACTOME_MICRORNA_MIRNA_BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.1 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway