Motif ID: Fubp1

Z-value: 0.725


Transcription factors associated with Fubp1:

Gene SymbolEntrez IDGene Name
Fubp1 ENSMUSG00000028034.9 Fubp1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Fubp1mm10_v2_chr3_+_152210458_1522105340.324.1e-02Click!


Activity profile for motif Fubp1.

activity profile for motif Fubp1


Sorted Z-values histogram for motif Fubp1

Sorted Z-values for motif Fubp1



Network of associatons between targets according to the STRING database.



First level regulatory network of Fubp1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_44617310 6.851 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
Ebf1


early B cell factor 1


chrX_-_106485214 5.894 ENSMUST00000039447.7
Fndc3c1
fibronectin type III domain containing 3C1
chr18_+_86711520 4.197 ENSMUST00000122464.1
Cbln2
cerebellin 2 precursor protein
chr14_-_98169542 3.740 ENSMUST00000069334.7
ENSMUST00000071533.6
Dach1

dachshund 1 (Drosophila)

chr14_-_48667508 3.688 ENSMUST00000144465.1
ENSMUST00000133479.1
ENSMUST00000119070.1
ENSMUST00000152018.1
Otx2



orthodenticle homolog 2 (Drosophila)



chr18_+_86711059 3.635 ENSMUST00000068423.3
Cbln2
cerebellin 2 precursor protein
chr7_-_137314394 2.953 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
Ebf3



early B cell factor 3



chr13_-_21780616 2.602 ENSMUST00000080511.2
Hist1h1b
histone cluster 1, H1b
chr1_+_156366037 2.488 ENSMUST00000102782.3
Gm2000
predicted gene 2000
chr3_-_157925056 2.468 ENSMUST00000118539.1
Cth
cystathionase (cystathionine gamma-lyase)
chr2_+_103970115 2.350 ENSMUST00000111143.1
ENSMUST00000138815.1
Lmo2

LIM domain only 2

chr2_-_28916412 2.346 ENSMUST00000050776.2
ENSMUST00000113849.1
Barhl1

BarH-like 1 (Drosophila)

chr2_+_103970221 2.248 ENSMUST00000111140.2
ENSMUST00000111139.2
Lmo2

LIM domain only 2

chr2_-_69206146 2.237 ENSMUST00000127243.1
ENSMUST00000149643.1
ENSMUST00000167875.2
ENSMUST00000005365.8
Spc25



SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)



chr2_+_103969528 1.874 ENSMUST00000123437.1
ENSMUST00000163256.1
Lmo2

LIM domain only 2

chr2_-_69206133 1.837 ENSMUST00000112320.1
Spc25
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr18_-_34751502 1.808 ENSMUST00000060710.7
Cdc25c
cell division cycle 25C
chr11_-_17211504 1.790 ENSMUST00000020317.7
Pno1
partner of NOB1 homolog (S. cerevisiae)
chr13_-_78199757 1.511 ENSMUST00000091458.6
Nr2f1
nuclear receptor subfamily 2, group F, member 1
chr6_+_17307632 1.472 ENSMUST00000115453.1
Cav1
caveolin 1, caveolae protein
chr18_-_84086379 1.455 ENSMUST00000060303.8
Tshz1
teashirt zinc finger family member 1
chr4_-_55532453 1.435 ENSMUST00000132746.1
ENSMUST00000107619.2
Klf4

Kruppel-like factor 4 (gut)

chr18_+_35536539 1.434 ENSMUST00000081864.3
Gm5239
predicted pseudogene 5239
chr10_-_128549102 1.429 ENSMUST00000176906.1
Rpl41
ribosomal protein L41
chr10_+_50895651 1.424 ENSMUST00000020071.3
Sim1
single-minded homolog 1 (Drosophila)
chr12_-_80112998 1.393 ENSMUST00000165114.1
ENSMUST00000021552.1
Zfp36l1

zinc finger protein 36, C3H type-like 1

chr7_+_31059342 1.392 ENSMUST00000039775.7
Lgi4
leucine-rich repeat LGI family, member 4
chr10_+_53596936 1.321 ENSMUST00000020004.6
Asf1a
ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chr13_-_78196373 1.316 ENSMUST00000125176.2
Nr2f1
nuclear receptor subfamily 2, group F, member 1
chr4_+_118409331 1.296 ENSMUST00000084319.4
ENSMUST00000106384.3
ENSMUST00000126089.1
ENSMUST00000073881.1
ENSMUST00000019229.8
ENSMUST00000144577.1
Med8





mediator of RNA polymerase II transcription, subunit 8 homolog (yeast)





chrX_+_150594420 1.260 ENSMUST00000112713.2
Pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr18_+_34751803 1.236 ENSMUST00000181453.1
ENSMUST00000181641.1
2010110K18Rik

RIKEN cDNA 2010110K18 gene

chr18_+_35770318 1.231 ENSMUST00000165299.1
Gm16490
predicted gene 16490
chr10_-_33624587 1.217 ENSMUST00000160299.1
ENSMUST00000019920.6
Clvs2

clavesin 2

chr19_+_4192129 1.190 ENSMUST00000046094.4
Ppp1ca
protein phosphatase 1, catalytic subunit, alpha isoform
chr17_-_15826521 1.173 ENSMUST00000170578.1
Rgmb
RGM domain family, member B
chr7_+_89404356 1.123 ENSMUST00000058755.3
Fzd4
frizzled homolog 4 (Drosophila)
chr8_-_89044162 1.118 ENSMUST00000034090.6
Sall1
sal-like 1 (Drosophila)
chr17_+_35049966 1.091 ENSMUST00000007257.9
Clic1
chloride intracellular channel 1
chr10_-_88605017 1.070 ENSMUST00000119185.1
ENSMUST00000121629.1
Mybpc1

myosin binding protein C, slow-type

chr3_+_87906321 1.067 ENSMUST00000005017.8
Hdgf
hepatoma-derived growth factor
chr7_-_110862944 1.034 ENSMUST00000033050.3
Lyve1
lymphatic vessel endothelial hyaluronan receptor 1
chr5_-_5266038 1.011 ENSMUST00000115451.1
ENSMUST00000115452.1
ENSMUST00000131392.1
Cdk14


cyclin-dependent kinase 14


chr18_-_77767752 0.946 ENSMUST00000048192.7
Haus1
HAUS augmin-like complex, subunit 1
chr12_+_17266545 0.910 ENSMUST00000057288.5
Pdia6
protein disulfide isomerase associated 6
chr13_-_21501418 0.899 ENSMUST00000044043.2
Gm11273
predicted gene 11273
chr19_+_53140430 0.893 ENSMUST00000111741.2
Add3
adducin 3 (gamma)
chr12_+_55384222 0.892 ENSMUST00000163070.1
Psma6
proteasome (prosome, macropain) subunit, alpha type 6
chrX_-_48513518 0.882 ENSMUST00000114945.2
ENSMUST00000037349.7
Aifm1

apoptosis-inducing factor, mitochondrion-associated 1

chr12_-_84617326 0.846 ENSMUST00000021666.4
Abcd4
ATP-binding cassette, sub-family D (ALD), member 4
chr7_+_58658181 0.829 ENSMUST00000168747.1
Atp10a
ATPase, class V, type 10A
chr10_+_14523062 0.829 ENSMUST00000096020.5
Gm10335
predicted gene 10335
chr16_-_94370695 0.820 ENSMUST00000113906.2
Pigp
phosphatidylinositol glycan anchor biosynthesis, class P
chr2_+_3114220 0.802 ENSMUST00000072955.5
Fam171a1
family with sequence similarity 171, member A1
chr12_+_109545390 0.802 ENSMUST00000146701.1
Meg3
maternally expressed 3
chr8_-_105758570 0.758 ENSMUST00000155038.2
ENSMUST00000013294.9
Gfod2

glucose-fructose oxidoreductase domain containing 2

chr15_+_37233036 0.739 ENSMUST00000161405.1
ENSMUST00000022895.8
ENSMUST00000161532.1
Grhl2


grainyhead-like 2 (Drosophila)


chr5_+_138363719 0.736 ENSMUST00000100526.2
Gm10874
predicted gene 10874
chr16_-_46155077 0.732 ENSMUST00000059524.5
Gm4737
predicted gene 4737
chr11_+_117232254 0.729 ENSMUST00000106354.2
Sept9
septin 9
chr3_+_122924353 0.727 ENSMUST00000106429.3
1810037I17Rik
RIKEN cDNA 1810037I17 gene
chr16_+_13819251 0.714 ENSMUST00000023362.8
ENSMUST00000115805.1
Ntan1

N-terminal Asn amidase

chr17_+_26252903 0.713 ENSMUST00000025023.7
Luc7l
Luc7 homolog (S. cerevisiae)-like
chr11_-_68973840 0.691 ENSMUST00000038644.4
Rangrf
RAN guanine nucleotide release factor
chr5_+_110839973 0.688 ENSMUST00000066160.1
Chek2
checkpoint kinase 2
chr3_+_96629919 0.650 ENSMUST00000048915.6
Rbm8a
RNA binding motif protein 8a
chr2_+_104069819 0.646 ENSMUST00000111131.2
ENSMUST00000111132.1
ENSMUST00000129749.1
Cd59b


CD59b antigen


chr2_-_148045891 0.644 ENSMUST00000109964.1
Foxa2
forkhead box A2
chr3_+_137341103 0.644 ENSMUST00000119475.1
Emcn
endomucin
chrX_+_94636066 0.600 ENSMUST00000096368.3
Gspt2
G1 to S phase transition 2
chr7_-_116084635 0.598 ENSMUST00000111755.3
Gm4353
predicted gene 4353
chr14_+_11227511 0.589 ENSMUST00000080237.3
Rpl21-ps4
ribosomal protein L21, pseudogene 4
chr3_+_137341067 0.574 ENSMUST00000122064.1
Emcn
endomucin
chr18_-_31911903 0.571 ENSMUST00000054984.6
Sft2d3
SFT2 domain containing 3
chr2_+_10372426 0.568 ENSMUST00000114864.2
ENSMUST00000116594.2
ENSMUST00000041105.6
Sfmbt2


Scm-like with four mbt domains 2


chr16_-_94370647 0.567 ENSMUST00000113910.1
Pigp
phosphatidylinositol glycan anchor biosynthesis, class P
chr8_+_84415348 0.560 ENSMUST00000121390.1
ENSMUST00000122053.1
Cacna1a

calcium channel, voltage-dependent, P/Q type, alpha 1A subunit

chr5_-_110269816 0.559 ENSMUST00000059229.9
ENSMUST00000112505.2
Pgam5

phosphoglycerate mutase family member 5

chr5_-_124354671 0.556 ENSMUST00000031341.4
Cdk2ap1
CDK2 (cyclin-dependent kinase 2)-associated protein 1
chr10_+_94576254 0.554 ENSMUST00000117929.1
Tmcc3
transmembrane and coiled coil domains 3
chr7_-_30626145 0.536 ENSMUST00000075738.4
Cox6b1
cytochrome c oxidase, subunit VIb polypeptide 1
chr6_-_113377510 0.523 ENSMUST00000099118.2
Tada3
transcriptional adaptor 3
chr17_+_26781060 0.521 ENSMUST00000015725.8
ENSMUST00000135824.1
ENSMUST00000137989.1
Bnip1


BCL2/adenovirus E1B interacting protein 1


chr5_-_44799643 0.494 ENSMUST00000070748.5
Ldb2
LIM domain binding 2
chr12_+_69963452 0.491 ENSMUST00000110560.1
Gm3086
predicted gene 3086
chr5_+_122391878 0.449 ENSMUST00000102525.4
Arpc3
actin related protein 2/3 complex, subunit 3
chr3_-_109027600 0.444 ENSMUST00000171143.1
Fam102b
family with sequence similarity 102, member B
chrX_-_51018011 0.441 ENSMUST00000053593.7
Rap2c
RAP2C, member of RAS oncogene family
chr15_-_89379246 0.434 ENSMUST00000049968.7
Odf3b
outer dense fiber of sperm tails 3B
chr4_+_123282778 0.431 ENSMUST00000106243.1
ENSMUST00000106241.1
ENSMUST00000080178.6
Pabpc4


poly(A) binding protein, cytoplasmic 4


chr5_-_135394499 0.400 ENSMUST00000065638.4
ENSMUST00000111171.2
Pom121

nuclear pore membrane protein 121

chr16_-_94370450 0.396 ENSMUST00000138514.1
Pigp
phosphatidylinositol glycan anchor biosynthesis, class P
chr2_+_48814109 0.380 ENSMUST00000063886.3
Acvr2a
activin receptor IIA
chr17_-_30612613 0.375 ENSMUST00000167624.1
ENSMUST00000024823.6
Glo1

glyoxalase 1

chr2_-_32353283 0.369 ENSMUST00000091089.5
ENSMUST00000113350.1
Dnm1

dynamin 1

chr2_-_32353247 0.351 ENSMUST00000078352.5
ENSMUST00000113352.2
ENSMUST00000113365.1
Dnm1


dynamin 1


chr1_+_153905301 0.351 ENSMUST00000105679.3
A930039A15Rik
RIKEN cDNA A930039A15 gene
chr4_+_109343029 0.350 ENSMUST00000030281.5
Eps15
epidermal growth factor receptor pathway substrate 15
chr9_+_109875541 0.332 ENSMUST00000094324.3
Cdc25a
cell division cycle 25A
chr5_+_135369942 0.331 ENSMUST00000000940.8
Nsun5
NOL1/NOP2/Sun domain family, member 5
chr9_-_48835932 0.314 ENSMUST00000093852.3
Zbtb16
zinc finger and BTB domain containing 16
chr2_-_128967725 0.303 ENSMUST00000099385.2
Gm10762
predicted gene 10762
chr2_+_104590453 0.301 ENSMUST00000028599.7
Cstf3
cleavage stimulation factor, 3' pre-RNA, subunit 3
chr3_+_87906842 0.283 ENSMUST00000159492.1
Hdgf
hepatoma-derived growth factor
chr4_-_130275213 0.280 ENSMUST00000122374.1
Serinc2
serine incorporator 2
chr6_-_129533267 0.258 ENSMUST00000181594.1
1700101I11Rik
RIKEN cDNA 1700101I11 gene
chr19_+_8617991 0.249 ENSMUST00000010250.2
Slc22a6
solute carrier family 22 (organic anion transporter), member 6
chr14_+_61599493 0.242 ENSMUST00000039562.6
Trim13
tripartite motif-containing 13
chr11_+_4895316 0.232 ENSMUST00000101615.2
Thoc5
THO complex 5
chr7_+_75643223 0.225 ENSMUST00000137959.1
Akap13
A kinase (PRKA) anchor protein 13
chr9_+_22454290 0.223 ENSMUST00000168332.1
Gm17545
predicted gene, 17545
chr7_-_139582790 0.211 ENSMUST00000106095.2
Nkx6-2
NK6 homeobox 2
chr9_+_106821874 0.170 ENSMUST00000159645.1
Vprbp
Vpr (HIV-1) binding protein
chr11_+_4895328 0.148 ENSMUST00000038237.1
Thoc5
THO complex 5
chr2_+_133552159 0.144 ENSMUST00000028836.6
Bmp2
bone morphogenetic protein 2
chr6_+_83165920 0.143 ENSMUST00000077407.5
ENSMUST00000113913.1
ENSMUST00000130212.1
Dctn1


dynactin 1


chr11_-_102319093 0.143 ENSMUST00000174302.1
ENSMUST00000178839.1
ENSMUST00000006754.7
Ubtf


upstream binding transcription factor, RNA polymerase I


chr10_+_128267997 0.135 ENSMUST00000050901.2
Apof
apolipoprotein F
chr11_-_106715251 0.124 ENSMUST00000080853.4
ENSMUST00000183610.1
ENSMUST00000103069.3
ENSMUST00000106796.2
Pecam1



platelet/endothelial cell adhesion molecule 1



chr9_-_103202113 0.110 ENSMUST00000035157.8
Srprb
signal recognition particle receptor, B subunit
chr6_-_122856151 0.105 ENSMUST00000042081.8
C3ar1
complement component 3a receptor 1
chr11_-_69681903 0.102 ENSMUST00000066760.1
Senp3
SUMO/sentrin specific peptidase 3
chr18_-_70141568 0.101 ENSMUST00000121693.1
Rab27b
RAB27b, member RAS oncogene family
chr10_+_39420009 0.088 ENSMUST00000157009.1
Fyn
Fyn proto-oncogene
chr5_+_147430153 0.088 ENSMUST00000031651.8
Pan3
PAN3 polyA specific ribonuclease subunit homolog (S. cerevisiae)
chr16_+_8470763 0.080 ENSMUST00000046470.9
ENSMUST00000150790.1
ENSMUST00000142899.1
Mettl22


methyltransferase like 22


chr15_+_41789495 0.069 ENSMUST00000090095.5
ENSMUST00000022918.7
Oxr1

oxidation resistance 1

chr19_+_44562841 0.069 ENSMUST00000040455.4
Hif1an
hypoxia-inducible factor 1, alpha subunit inhibitor
chr17_-_27204357 0.035 ENSMUST00000055117.7
Lemd2
LEM domain containing 2
chr9_-_118150196 0.022 ENSMUST00000044220.9
Cmc1
COX assembly mitochondrial protein 1
chr12_-_91590009 0.009 ENSMUST00000021345.6
Gtf2a1
general transcription factor II A, 1
chr10_-_130280218 0.005 ENSMUST00000061571.3
Neurod4
neurogenic differentiation 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.9 3.7 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.8 2.5 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.5 6.5 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.5 1.5 GO:0060023 soft palate development(GO:0060023)
0.5 1.4 GO:0014738 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.5 1.4 GO:1904580 regulation of intracellular mRNA localization(GO:1904580)
0.4 1.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.4 1.1 GO:0072092 ureteric bud invasion(GO:0072092)
0.3 1.5 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.2 0.7 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.2 0.6 GO:0045014 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594)
0.2 1.1 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.2 0.6 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.2 0.6 GO:0050883 regulation of sulfur amino acid metabolic process(GO:0031335) musculoskeletal movement, spinal reflex action(GO:0050883)
0.2 1.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 2.8 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.2 0.7 GO:1903463 regulation of mitotic cell cycle DNA replication(GO:1903463)
0.2 1.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 0.8 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 0.6 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.1 0.4 GO:0046881 sperm ejaculation(GO:0042713) positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.1 0.7 GO:0086028 bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
0.1 0.2 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 1.0 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.1 0.7 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.1 0.9 GO:1902510 regulation of apoptotic DNA fragmentation(GO:1902510)
0.1 0.2 GO:0015747 urate transport(GO:0015747)
0.1 7.8 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 0.4 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.1 2.1 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.1 0.4 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.1 0.3 GO:0048133 NK T cell differentiation(GO:0001865) germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138) germline stem cell asymmetric division(GO:0098728)
0.0 0.4 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.1 GO:0060129 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.1 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 2.3 GO:0030901 midbrain development(GO:0030901)
0.0 1.3 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.3 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 1.4 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 1.8 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 4.1 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 0.2 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.4 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.4 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.3 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.1 GO:0050904 diapedesis(GO:0050904)
0.0 0.8 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.7 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.9 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.9 GO:0042493 response to drug(GO:0042493)
0.0 0.9 GO:0051225 spindle assembly(GO:0051225)
0.0 0.5 GO:0010669 epithelial structure maintenance(GO:0010669)
0.0 0.1 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.0 0.6 GO:0070266 necroptotic process(GO:0070266)
0.0 0.4 GO:0006999 nuclear pore organization(GO:0006999)
0.0 1.1 GO:0070527 platelet aggregation(GO:0070527)
0.0 1.2 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.8 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.7 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.1 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 1.4 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.1 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.2 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.1 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.4 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.6 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.5 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 1.2 GO:0030509 BMP signaling pathway(GO:0030509)
0.0 1.0 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.0 0.1 GO:0016926 protein desumoylation(GO:0016926)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.1 GO:0031262 Ndc80 complex(GO:0031262)
0.4 1.3 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.2 1.0 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.2 0.6 GO:0018444 translation release factor complex(GO:0018444)
0.2 1.1 GO:0005859 muscle myosin complex(GO:0005859)
0.2 1.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.4 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 1.8 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.9 GO:0070652 HAUS complex(GO:0070652)
0.1 1.5 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 0.9 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 0.9 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.6 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 1.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 1.1 GO:0010369 chromocenter(GO:0010369)
0.0 0.7 GO:0031105 septin complex(GO:0031105)
0.0 0.7 GO:0043196 varicosity(GO:0043196)
0.0 1.4 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.4 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 2.6 GO:0000786 nucleosome(GO:0000786)
0.0 1.3 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.4 GO:0000124 SAGA complex(GO:0000124)
0.0 1.1 GO:0034707 chloride channel complex(GO:0034707)
0.0 10.7 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.5 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.4 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.7 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 1.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 1.2 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.6 GO:0016235 aggresome(GO:0016235)
0.0 0.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.9 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.1 GO:0005869 dynactin complex(GO:0005869)
0.0 0.7 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 2.7 GO:0030426 growth cone(GO:0030426)
0.0 0.5 GO:0031201 SNARE complex(GO:0031201)
0.0 0.9 GO:0000794 condensed nuclear chromosome(GO:0000794)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.7 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.5 6.9 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.4 2.8 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.3 1.5 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.3 0.9 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.3 1.4 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.2 1.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.2 2.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 1.3 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.2 1.8 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 6.5 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 1.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.9 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.1 1.6 GO:0015026 coreceptor activity(GO:0015026)
0.1 0.6 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.7 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.1 1.2 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.7 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.1 1.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.5 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.8 GO:0050699 WW domain binding(GO:0050699)
0.0 0.5 GO:0050733 RS domain binding(GO:0050733)
0.0 1.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 5.1 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.9 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.8 GO:0001848 complement binding(GO:0001848)
0.0 0.8 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.6 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.1 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.3 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 1.3 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 5.9 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.7 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.9 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.7 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 PID_ALK1_PATHWAY ALK1 signaling events
0.1 2.8 PID_ATM_PATHWAY ATM pathway
0.0 1.1 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 7.0 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 1.2 PID_BMP_PATHWAY BMP receptor signaling
0.0 0.7 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.9 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.0 0.6 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.4 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.7 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.5 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.2 2.6 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 9.6 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 2.5 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 1.4 REACTOME_DESTABILIZATION_OF_MRNA_BY_BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1 1.8 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 1.3 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 2.8 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 2.5 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.2 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.3 REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 1.1 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 4.1 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.7 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.0 1.3 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.6 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.8 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.0 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.2 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 1.2 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.4 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.0 0.4 REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.9 REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 2.0 REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.1 REACTOME_PLATELET_SENSITIZATION_BY_LDL Genes involved in Platelet sensitization by LDL
0.0 1.1 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.4 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation