Motif ID: Zbtb16

Z-value: 1.196


Transcription factors associated with Zbtb16:

Gene SymbolEntrez IDGene Name
Zbtb16 ENSMUSG00000066687.4 Zbtb16

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb16mm10_v2_chr9_-_48835932_48835962-0.086.1e-01Click!


Activity profile for motif Zbtb16.

activity profile for motif Zbtb16


Sorted Z-values histogram for motif Zbtb16

Sorted Z-values for motif Zbtb16



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb16

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrY_+_90785442 15.235 ENSMUST00000177591.1
ENSMUST00000177671.1
ENSMUST00000179077.1
Erdr1


erythroid differentiation regulator 1


chrX_+_170010744 13.693 ENSMUST00000178789.1
Gm21887
predicted gene, 21887
chr9_-_79977782 6.313 ENSMUST00000093811.4
Filip1
filamin A interacting protein 1
chrX_+_170009892 6.145 ENSMUST00000180251.1
Gm21887
predicted gene, 21887
chr4_+_44300876 5.944 ENSMUST00000045607.5
Melk
maternal embryonic leucine zipper kinase
chr4_-_117178726 5.343 ENSMUST00000153953.1
ENSMUST00000106436.1
Kif2c

kinesin family member 2C

chr1_+_107511489 5.267 ENSMUST00000064916.2
Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr1_+_107511416 5.206 ENSMUST00000009356.4
Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr11_+_69045640 3.990 ENSMUST00000108666.1
ENSMUST00000021277.5
Aurkb

aurora kinase B

chr17_-_26099257 3.396 ENSMUST00000053575.3
Gm8186
predicted gene 8186
chr5_+_110330697 3.396 ENSMUST00000112481.1
Pole
polymerase (DNA directed), epsilon
chr1_-_150465563 3.262 ENSMUST00000164600.1
ENSMUST00000111902.2
ENSMUST00000111901.2
ENSMUST00000006171.9
Prg4



proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)



chr14_-_65833963 3.180 ENSMUST00000022613.9
Esco2
establishment of cohesion 1 homolog 2 (S. cerevisiae)
chr10_+_75589363 3.104 ENSMUST00000072217.2
Ggt5
gamma-glutamyltransferase 5
chr3_-_157925056 2.973 ENSMUST00000118539.1
Cth
cystathionase (cystathionine gamma-lyase)
chr11_-_106998483 2.873 ENSMUST00000124541.1
Kpna2
karyopherin (importin) alpha 2
chr6_+_137754529 2.734 ENSMUST00000087675.6
Dera
2-deoxyribose-5-phosphate aldolase homolog (C. elegans)
chr5_-_149051300 2.712 ENSMUST00000110505.1
Hmgb1
high mobility group box 1
chr2_-_72986716 2.677 ENSMUST00000112062.1
Gm11084
predicted gene 11084
chr19_+_53140430 2.676 ENSMUST00000111741.2
Add3
adducin 3 (gamma)
chr4_+_86930691 2.643 ENSMUST00000164590.1
Acer2
alkaline ceramidase 2
chr17_+_46496753 2.523 ENSMUST00000046497.6
Dnph1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr6_+_6863269 2.500 ENSMUST00000160937.2
ENSMUST00000171311.1
Dlx6

distal-less homeobox 6

chr19_-_30175414 2.485 ENSMUST00000025778.7
Gldc
glycine decarboxylase
chr3_+_116878227 2.474 ENSMUST00000040260.6
Frrs1
ferric-chelate reductase 1
chr3_-_33082004 2.411 ENSMUST00000108225.3
Pex5l
peroxisomal biogenesis factor 5-like
chr10_+_22360552 2.399 ENSMUST00000182677.1
Raet1d
retinoic acid early transcript delta
chrY_+_90784738 2.388 ENSMUST00000179483.1
Erdr1
erythroid differentiation regulator 1
chr1_+_109983737 2.382 ENSMUST00000172005.1
Cdh7
cadherin 7, type 2
chr5_+_90367204 2.292 ENSMUST00000068250.3
Gm9958
predicted gene 9958
chr11_+_101627942 2.223 ENSMUST00000010506.3
Rdm1
RAD52 motif 1
chr17_+_26252903 2.165 ENSMUST00000025023.7
Luc7l
Luc7 homolog (S. cerevisiae)-like
chr11_+_23665615 2.114 ENSMUST00000109525.1
ENSMUST00000020520.4
Pus10

pseudouridylate synthase 10

chr8_+_95534078 2.103 ENSMUST00000041569.3
Ccdc113
coiled-coil domain containing 113
chr4_+_15957923 2.028 ENSMUST00000029879.8
ENSMUST00000149069.1
Nbn

nibrin

chrX_-_134111852 1.995 ENSMUST00000033610.6
Nox1
NADPH oxidase 1
chr12_+_109544498 1.988 ENSMUST00000126289.1
Meg3
maternally expressed 3
chr9_-_69451035 1.952 ENSMUST00000071565.5
Gm4978
predicted gene 4978
chr5_-_115134907 1.939 ENSMUST00000060798.5
Unc119b
unc-119 homolog B (C. elegans)
chr4_-_119320417 1.905 ENSMUST00000147077.1
ENSMUST00000056458.7
ENSMUST00000106321.2
ENSMUST00000106319.1
ENSMUST00000106317.1
ENSMUST00000106318.1
Ppih





peptidyl prolyl isomerase H





chr11_-_102819663 1.844 ENSMUST00000092567.4
Gjc1
gap junction protein, gamma 1
chr8_-_106573461 1.643 ENSMUST00000073722.5
Gm10073
predicted pseudogene 10073
chr19_-_29334646 1.609 ENSMUST00000044143.5
Rln1
relaxin 1
chr13_+_54071815 1.590 ENSMUST00000021930.8
Sfxn1
sideroflexin 1
chr13_+_55727345 1.579 ENSMUST00000124968.1
ENSMUST00000021958.5
Pcbd2

pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2

chr17_-_53539411 1.551 ENSMUST00000056198.3
Pp2d1
protein phosphatase 2C-like domain containing 1
chr5_-_16731074 1.516 ENSMUST00000073014.5
Gm8991
predicted pseudogene 8991
chr7_-_19604444 1.502 ENSMUST00000086041.5
Clasrp
CLK4-associating serine/arginine rich protein
chr11_-_93965957 1.489 ENSMUST00000021220.3
Nme1
NME/NM23 nucleoside diphosphate kinase 1
chr18_-_35662180 1.489 ENSMUST00000025209.4
ENSMUST00000096573.2
Spata24

spermatogenesis associated 24

chr13_-_73989148 1.481 ENSMUST00000071737.4
Gm10126
predicted gene 10126
chr12_-_31713873 1.445 ENSMUST00000057783.4
ENSMUST00000174480.2
ENSMUST00000176710.1
Gpr22


G protein-coupled receptor 22


chr4_-_94556737 1.420 ENSMUST00000030313.8
Caap1
caspase activity and apoptosis inhibitor 1
chr12_-_87233556 1.406 ENSMUST00000021423.7
Noxred1
NADP+ dependent oxidoreductase domain containing 1
chr9_+_50617516 1.406 ENSMUST00000141366.1
Pih1d2
PIH1 domain containing 2
chr10_-_80900749 1.387 ENSMUST00000020440.6
Timm13
translocase of inner mitochondrial membrane 13
chr3_+_138143888 1.386 ENSMUST00000161141.1
Trmt10a
tRNA methyltransferase 10A
chr13_+_113342548 1.382 ENSMUST00000078163.7
BC067074
cDNA sequence BC067074
chr17_+_70929006 1.344 ENSMUST00000092011.6
Gm16519
predicted gene, 16519
chr5_-_65335597 1.299 ENSMUST00000172660.1
ENSMUST00000172732.1
ENSMUST00000031092.8
Rfc1


replication factor C (activator 1) 1


chrX_-_7188713 1.265 ENSMUST00000004428.7
Clcn5
chloride channel 5
chr1_+_74391479 1.254 ENSMUST00000027367.7
Ctdsp1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr7_-_16387791 1.217 ENSMUST00000094815.3
Sae1
SUMO1 activating enzyme subunit 1
chr2_-_170131156 1.214 ENSMUST00000063710.6
Zfp217
zinc finger protein 217
chr10_-_88605017 1.204 ENSMUST00000119185.1
ENSMUST00000121629.1
Mybpc1

myosin binding protein C, slow-type

chr17_-_70998010 1.188 ENSMUST00000024846.6
Myl12a
myosin, light chain 12A, regulatory, non-sarcomeric
chr4_+_80910646 1.186 ENSMUST00000055922.3
Lurap1l
leucine rich adaptor protein 1-like
chrY_+_90843934 1.180 ENSMUST00000178550.1
Gm21742
predicted gene, 21742
chr4_-_119383732 1.156 ENSMUST00000044781.2
ENSMUST00000084307.3
Ccdc30

coiled-coil domain containing 30

chr18_+_77773956 1.143 ENSMUST00000114748.1
Atp5a1
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1
chr11_-_5707658 1.121 ENSMUST00000154330.1
Mrps24
mitochondrial ribosomal protein S24
chr10_-_127751707 1.082 ENSMUST00000079692.5
Gpr182
G protein-coupled receptor 182
chr7_-_116084635 1.079 ENSMUST00000111755.3
Gm4353
predicted gene 4353
chr4_+_32623985 1.069 ENSMUST00000108178.1
Casp8ap2
caspase 8 associated protein 2
chr5_-_65335564 1.002 ENSMUST00000172780.1
Rfc1
replication factor C (activator 1) 1
chr4_+_129287614 0.995 ENSMUST00000102599.3
Sync
syncoilin
chr5_+_138161071 0.993 ENSMUST00000019638.8
ENSMUST00000110951.1
Cops6

COP9 (constitutive photomorphogenic) homolog, subunit 6 (Arabidopsis thaliana)

chr5_-_121527186 0.975 ENSMUST00000152270.1
Mapkapk5
MAP kinase-activated protein kinase 5
chr15_+_79670856 0.968 ENSMUST00000023062.3
Tomm22
translocase of outer mitochondrial membrane 22 homolog (yeast)
chrX_-_97377190 0.958 ENSMUST00000037353.3
Eda2r
ectodysplasin A2 receptor
chr10_+_33905015 0.941 ENSMUST00000169670.1
Rsph4a
radial spoke head 4 homolog A (Chlamydomonas)
chr4_-_108118528 0.938 ENSMUST00000030340.8
Scp2
sterol carrier protein 2, liver
chr3_-_41742471 0.917 ENSMUST00000026866.8
Sclt1
sodium channel and clathrin linker 1
chr4_-_136053343 0.905 ENSMUST00000102536.4
Rpl11
ribosomal protein L11
chr7_+_141029131 0.896 ENSMUST00000170892.1
Gm17387
predicted gene, 17387
chr4_+_149104130 0.893 ENSMUST00000103216.3
ENSMUST00000030816.3
Dffa

DNA fragmentation factor, alpha subunit

chr3_+_138143799 0.888 ENSMUST00000159622.1
Trmt10a
tRNA methyltransferase 10A
chrX_-_75843063 0.887 ENSMUST00000114057.1
Pls3
plastin 3 (T-isoform)
chr11_+_114668524 0.882 ENSMUST00000106602.3
ENSMUST00000077915.3
ENSMUST00000106599.1
ENSMUST00000082092.4
Rpl38



ribosomal protein L38



chr8_+_83566671 0.879 ENSMUST00000036996.5
Ndufb7
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7
chr11_-_17953861 0.877 ENSMUST00000076661.6
Etaa1
Ewing's tumor-associated antigen 1
chr15_-_98662858 0.876 ENSMUST00000162384.1
ENSMUST00000003450.8
Ddx23

DEAD (Asp-Glu-Ala-Asp) box polypeptide 23

chr3_+_41742615 0.873 ENSMUST00000146165.1
ENSMUST00000119572.1
ENSMUST00000108065.2
ENSMUST00000120167.1
ENSMUST00000026867.7
ENSMUST00000026868.7
D3Ertd751e





DNA segment, Chr 3, ERATO Doi 751, expressed





chr1_+_58802492 0.868 ENSMUST00000165549.1
Casp8
caspase 8
chr7_+_28169744 0.843 ENSMUST00000042405.6
Fbl
fibrillarin
chr2_-_6130117 0.834 ENSMUST00000126551.1
ENSMUST00000054254.5
ENSMUST00000114942.2
Proser2


proline and serine rich 2


chr7_-_115846080 0.828 ENSMUST00000166207.1
Sox6
SRY-box containing gene 6
chr16_-_56712825 0.822 ENSMUST00000136394.1
Tfg
Trk-fused gene
chr17_-_80563834 0.819 ENSMUST00000086545.4
Cdkl4
cyclin-dependent kinase-like 4
chr19_-_8786408 0.816 ENSMUST00000176496.1
Taf6l
TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
chr18_+_33464163 0.813 ENSMUST00000097634.3
Gm10549
predicted gene 10549
chr10_-_127522428 0.812 ENSMUST00000026470.4
Shmt2
serine hydroxymethyltransferase 2 (mitochondrial)
chr7_+_4792874 0.791 ENSMUST00000032597.5
ENSMUST00000078432.4
Rpl28

ribosomal protein L28

chr5_-_72168142 0.786 ENSMUST00000013693.6
Commd8
COMM domain containing 8
chr3_+_95111013 0.781 ENSMUST00000009102.8
Vps72
vacuolar protein sorting 72 (yeast)
chr3_+_138143846 0.773 ENSMUST00000159481.1
Trmt10a
tRNA methyltransferase 10A
chr7_+_127470354 0.757 ENSMUST00000106292.1
Prr14
proline rich 14
chr13_+_30136529 0.748 ENSMUST00000152798.1
Mboat1
membrane bound O-acyltransferase domain containing 1
chr5_-_130255525 0.732 ENSMUST00000026387.4
Sbds
Shwachman-Bodian-Diamond syndrome homolog (human)
chr9_+_105053239 0.725 ENSMUST00000035177.8
ENSMUST00000149243.1
Mrpl3

mitochondrial ribosomal protein L3

chr8_+_70616816 0.717 ENSMUST00000052437.3
Lrrc25
leucine rich repeat containing 25
chr5_+_121803008 0.711 ENSMUST00000161159.1
Atxn2
ataxin 2
chr17_-_10320229 0.708 ENSMUST00000053066.6
Qk
quaking
chr10_-_20725023 0.701 ENSMUST00000020165.7
Pde7b
phosphodiesterase 7B
chr10_-_116549101 0.693 ENSMUST00000164088.1
Cnot2
CCR4-NOT transcription complex, subunit 2
chr5_-_135394499 0.677 ENSMUST00000065638.4
ENSMUST00000111171.2
Pom121

nuclear pore membrane protein 121

chr10_+_63024512 0.659 ENSMUST00000020262.4
Pbld2
phenazine biosynthesis-like protein domain containing 2
chr4_+_107367757 0.652 ENSMUST00000139560.1
Ndc1
NDC1 transmembrane nucleoporin
chr4_-_141139727 0.651 ENSMUST00000148204.1
ENSMUST00000102487.3
Szrd1

SUZ RNA binding domain containing 1

chr5_+_121802230 0.622 ENSMUST00000162995.1
Atxn2
ataxin 2
chr1_-_128417352 0.616 ENSMUST00000027602.8
ENSMUST00000064309.7
Dars

aspartyl-tRNA synthetase

chr8_+_88174560 0.615 ENSMUST00000074808.2
9430002A10Rik
RIKEN cDNA 9430002A10 gene
chr6_-_30390997 0.609 ENSMUST00000152391.2
ENSMUST00000115184.1
ENSMUST00000080812.7
ENSMUST00000102992.3
Zc3hc1



zinc finger, C3HC type 1



chr12_+_84417196 0.604 ENSMUST00000183146.1
Rnf113a2
ring finger protein 113A2
chr12_+_109545390 0.595 ENSMUST00000146701.1
Meg3
maternally expressed 3
chr16_+_90826719 0.588 ENSMUST00000099548.2
Eva1c
eva-1 homolog C (C. elegans)
chr11_+_69964758 0.588 ENSMUST00000108597.1
ENSMUST00000060651.5
ENSMUST00000108596.1
Cldn7


claudin 7


chr6_+_91878034 0.581 ENSMUST00000037783.5
Ccdc174
coiled-coil domain containing 174
chr1_-_133701881 0.580 ENSMUST00000167348.1
Gm17678
predicted gene, 17678
chr11_-_78183551 0.572 ENSMUST00000102483.4
Rpl23a
ribosomal protein L23A
chr11_-_101417615 0.567 ENSMUST00000070395.8
Aarsd1
alanyl-tRNA synthetase domain containing 1
chr11_+_78328415 0.562 ENSMUST00000048073.8
Pigs
phosphatidylinositol glycan anchor biosynthesis, class S
chr11_-_69008422 0.554 ENSMUST00000021282.5
Pfas
phosphoribosylformylglycinamidine synthase (FGAR amidotransferase)
chr17_+_46110982 0.550 ENSMUST00000024763.3
ENSMUST00000123646.1
Mrps18a

mitochondrial ribosomal protein S18A

chr4_+_123282778 0.549 ENSMUST00000106243.1
ENSMUST00000106241.1
ENSMUST00000080178.6
Pabpc4


poly(A) binding protein, cytoplasmic 4


chr9_-_50617428 0.541 ENSMUST00000131351.1
ENSMUST00000171462.1
AU019823

expressed sequence AU019823

chr7_-_125491586 0.535 ENSMUST00000033006.7
Nsmce1
non-SMC element 1 homolog (S. cerevisiae)
chr2_-_25627960 0.523 ENSMUST00000028307.8
Fcna
ficolin A
chr8_+_94532990 0.509 ENSMUST00000048653.2
ENSMUST00000109537.1
Cpne2

copine II

chr8_+_33517306 0.503 ENSMUST00000124496.1
Tex15
testis expressed gene 15
chr2_-_37647199 0.489 ENSMUST00000028279.3
Strbp
spermatid perinuclear RNA binding protein
chr6_-_118419388 0.470 ENSMUST00000032237.6
Bms1
BMS1 homolog, ribosome assembly protein (yeast)
chr9_+_20888175 0.468 ENSMUST00000004203.5
Ppan
peter pan homolog (Drosophila)
chr5_-_87490869 0.466 ENSMUST00000147854.1
Ugt2a1
UDP glucuronosyltransferase 2 family, polypeptide A1
chr1_+_45981548 0.451 ENSMUST00000085632.2
Rpl23a-ps1
ribosomal protein 23A, pseudogene 1
chrX_-_107403295 0.443 ENSMUST00000033591.5
Itm2a
integral membrane protein 2A
chr13_+_14613242 0.441 ENSMUST00000170836.2
Psma2
proteasome (prosome, macropain) subunit, alpha type 2
chr10_-_93891141 0.426 ENSMUST00000180840.1
Metap2
methionine aminopeptidase 2
chr13_-_60897439 0.422 ENSMUST00000171347.1
ENSMUST00000021884.8
Ctla2b

cytotoxic T lymphocyte-associated protein 2 beta

chr1_-_32547293 0.416 ENSMUST00000171322.1
Gm5415
predicted gene 5415
chr17_+_34564268 0.408 ENSMUST00000015612.7
Notch4
notch 4
chr5_+_92925400 0.406 ENSMUST00000172706.1
Shroom3
shroom family member 3
chr6_+_113333304 0.403 ENSMUST00000147945.1
Ogg1
8-oxoguanine DNA-glycosylase 1
chr14_-_73548242 0.402 ENSMUST00000043813.1
Nudt15
nudix (nucleoside diphosphate linked moiety X)-type motif 15
chr12_-_91590009 0.391 ENSMUST00000021345.6
Gtf2a1
general transcription factor II A, 1
chr2_-_50296680 0.357 ENSMUST00000144143.1
ENSMUST00000102769.4
ENSMUST00000133768.1
Mmadhc


methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria


chr17_+_35879770 0.356 ENSMUST00000025292.8
Dhx16
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr2_-_145935014 0.340 ENSMUST00000001818.4
Crnkl1
Crn, crooked neck-like 1 (Drosophila)
chr14_-_55643800 0.332 ENSMUST00000122358.1
Tm9sf1
transmembrane 9 superfamily member 1
chr7_-_38019505 0.323 ENSMUST00000085513.4
Uri1
URI1, prefoldin-like chaperone
chr8_-_72443772 0.321 ENSMUST00000019876.5
Calr3
calreticulin 3
chr8_+_106683052 0.315 ENSMUST00000048359.4
Tango6
transport and golgi organization 6
chr18_+_56562443 0.306 ENSMUST00000130163.1
ENSMUST00000132628.1
Phax

phosphorylated adaptor for RNA export

chr17_-_35175995 0.302 ENSMUST00000173324.1
Aif1
allograft inflammatory factor 1
chr15_-_99705490 0.281 ENSMUST00000163472.2
Gm17349
predicted gene, 17349
chr9_+_13619990 0.271 ENSMUST00000159294.1
Maml2
mastermind like 2 (Drosophila)
chrX_-_75578188 0.243 ENSMUST00000033545.5
Rab39b
RAB39B, member RAS oncogene family
chr2_+_132690120 0.237 ENSMUST00000148271.1
ENSMUST00000110132.2
1110034G24Rik

RIKEN cDNA 1110034G24 gene

chr4_+_155831272 0.233 ENSMUST00000139651.1
ENSMUST00000084097.5
Aurkaip1

aurora kinase A interacting protein 1

chr13_+_66904914 0.211 ENSMUST00000168767.2
Gm10767
predicted gene 10767
chrX_-_164076482 0.202 ENSMUST00000134272.1
Siah1b
seven in absentia 1B
chr15_+_6422240 0.201 ENSMUST00000163082.1
Dab2
disabled 2, mitogen-responsive phosphoprotein
chr11_+_100574904 0.191 ENSMUST00000103120.4
Cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
chr7_-_125491397 0.185 ENSMUST00000138616.1
Nsmce1
non-SMC element 1 homolog (S. cerevisiae)
chr15_-_36164872 0.180 ENSMUST00000058643.3
Fbxo43
F-box protein 43
chrX_-_97377150 0.179 ENSMUST00000113832.1
Eda2r
ectodysplasin A2 receptor
chr6_-_35308110 0.164 ENSMUST00000031868.4
Slc13a4
solute carrier family 13 (sodium/sulfate symporters), member 4
chr13_-_32781716 0.149 ENSMUST00000134352.1
ENSMUST00000057428.4
Mylk4

myosin light chain kinase family, member 4

chr13_+_30136498 0.143 ENSMUST00000047311.8
Mboat1
membrane bound O-acyltransferase domain containing 1
chr15_-_96699698 0.131 ENSMUST00000023099.6
Slc38a2
solute carrier family 38, member 2
chr11_-_106779483 0.125 ENSMUST00000021060.5
Polg2
polymerase (DNA directed), gamma 2, accessory subunit
chr13_+_94788873 0.119 ENSMUST00000046644.5
Tbca
tubulin cofactor A
chr3_-_101924378 0.107 ENSMUST00000106928.3
Slc22a15
solute carrier family 22 (organic anion/cation transporter), member 15
chr14_-_55643523 0.101 ENSMUST00000132338.1
Tm9sf1
transmembrane 9 superfamily member 1
chr14_+_30479565 0.094 ENSMUST00000022535.7
Dcp1a
DCP1 decapping enzyme homolog A (S. cerevisiae)
chr14_-_55092277 0.084 ENSMUST00000036328.8
Zfhx2
zinc finger homeobox 2
chr7_-_133782721 0.075 ENSMUST00000063669.1
Dhx32
DEAH (Asp-Glu-Ala-His) box polypeptide 32
chrX_-_111537947 0.072 ENSMUST00000132319.1
ENSMUST00000123951.1
Rps6ka6

ribosomal protein S6 kinase polypeptide 6

chr9_-_119157055 0.070 ENSMUST00000010795.4
Acaa1b
acetyl-Coenzyme A acyltransferase 1B
chr16_+_32271468 0.060 ENSMUST00000093183.3
Smco1
single-pass membrane protein with coiled-coil domains 1
chr14_-_55643720 0.058 ENSMUST00000138085.1
Tm9sf1
transmembrane 9 superfamily member 1
chr7_-_81855794 0.047 ENSMUST00000085094.3
Gm10160
predicted gene 10160
chr4_+_19605451 0.021 ENSMUST00000108250.2
Gm12353
predicted gene 12353

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
1.1 3.4 GO:0045004 DNA replication proofreading(GO:0045004)
1.1 5.3 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
1.0 3.0 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.9 2.7 GO:0045819 plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819)
0.9 2.6 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.8 2.5 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.8 3.3 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.8 3.1 GO:0006751 glutathione catabolic process(GO:0006751)
0.7 2.7 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.6 3.2 GO:0034421 post-translational protein acetylation(GO:0034421)
0.6 1.8 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.5 2.0 GO:0072592 regulation of integrin biosynthetic process(GO:0045113) oxygen metabolic process(GO:0072592)
0.4 2.0 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.4 1.6 GO:0010749 regulation of nitric oxide mediated signal transduction(GO:0010749)
0.4 2.4 GO:0051461 regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.3 0.9 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.3 2.5 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.3 1.4 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.3 0.8 GO:0006545 glycine biosynthetic process(GO:0006545)
0.3 18.4 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.2 1.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.2 1.6 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.2 0.9 GO:0048318 axial mesoderm development(GO:0048318)
0.2 2.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.2 1.4 GO:0006561 proline biosynthetic process(GO:0006561)
0.2 0.6 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.2 0.7 GO:0048539 bone marrow development(GO:0048539)
0.2 1.1 GO:0036337 Fas signaling pathway(GO:0036337)
0.2 0.8 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.2 0.9 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 1.5 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 0.4 GO:0042737 drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.1 1.0 GO:0090400 stress-induced premature senescence(GO:0090400)
0.1 2.9 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 1.9 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.1 0.9 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.1 0.6 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 0.9 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.1 2.6 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 5.9 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.1 3.0 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 0.3 GO:0051030 snRNA transport(GO:0051030)
0.1 0.3 GO:0014738 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.1 1.0 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.1 0.6 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.5 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 0.8 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.1 1.3 GO:0006999 nuclear pore organization(GO:0006999)
0.1 0.7 GO:0033147 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.1 0.6 GO:0043144 snoRNA processing(GO:0043144)
0.1 0.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.4 GO:0002317 plasma cell differentiation(GO:0002317) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1 10.4 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.1 0.4 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 0.9 GO:0051639 actin filament network formation(GO:0051639)
0.1 1.0 GO:0000338 protein deneddylation(GO:0000338)
0.1 0.4 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.1 0.7 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 1.2 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.0 1.1 GO:0043536 positive regulation of blood vessel endothelial cell migration(GO:0043536)
0.0 0.9 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.5 GO:0030539 male genitalia development(GO:0030539)
0.0 1.4 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.2 GO:0032346 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349)
0.0 0.5 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.0 0.2 GO:0032382 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373)
0.0 0.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.4 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 1.6 GO:0006826 iron ion transport(GO:0006826)
0.0 1.0 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.4 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.4 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.7 GO:0006301 postreplication repair(GO:0006301)
0.0 1.3 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.2 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 1.1 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 1.6 GO:0045843 negative regulation of striated muscle tissue development(GO:0045843)
0.0 2.0 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 2.5 GO:0060021 palate development(GO:0060021)
0.0 0.6 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.9 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.9 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.2 GO:0008272 sulfate transport(GO:0008272)
0.0 0.5 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.1 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.6 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.2 GO:0032460 negative regulation of protein oligomerization(GO:0032460) negative regulation of protein homooligomerization(GO:0032463)
0.0 1.0 GO:0007569 cell aging(GO:0007569)
0.0 1.5 GO:0007283 spermatogenesis(GO:0007283) male gamete generation(GO:0048232)
0.0 0.8 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.1 GO:0015838 amino-acid betaine transport(GO:0015838)
0.0 2.1 GO:0042493 response to drug(GO:0042493)
0.0 1.8 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.0 GO:0032133 chromosome passenger complex(GO:0032133)
0.7 3.4 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.6 1.9 GO:0071001 U4/U6 snRNP(GO:0071001)
0.6 2.4 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.6 2.4 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.5 2.0 GO:0071438 invadopodium membrane(GO:0071438)
0.4 1.2 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.4 2.3 GO:0005663 DNA replication factor C complex(GO:0005663)
0.3 2.0 GO:0030870 Mre11 complex(GO:0030870)
0.3 0.9 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.3 1.4 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.2 3.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.2 0.8 GO:0001651 dense fibrillar component(GO:0001651)
0.2 0.8 GO:0070552 BRISC complex(GO:0070552)
0.2 1.2 GO:0005859 muscle myosin complex(GO:0005859)
0.1 5.3 GO:0035371 microtubule plus-end(GO:0035371)
0.1 1.1 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 1.8 GO:0005922 connexon complex(GO:0005922)
0.1 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 1.0 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.7 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 0.6 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.9 GO:0071439 clathrin complex(GO:0071439)
0.1 1.2 GO:0016460 myosin II complex(GO:0016460)
0.1 0.7 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 1.6 GO:0071004 U2-type prespliceosome(GO:0071004)
0.1 0.4 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 2.1 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.3 GO:0071010 prespliceosome(GO:0071010)
0.1 2.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 1.0 GO:0032156 septin cytoskeleton(GO:0032156)
0.1 0.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 1.7 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.9 GO:0005682 U5 snRNP(GO:0005682)
0.0 4.2 GO:0005643 nuclear pore(GO:0005643)
0.0 1.7 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.4 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.6 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 3.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 2.5 GO:0005882 intermediate filament(GO:0005882)
0.0 0.8 GO:0030914 STAGA complex(GO:0030914)
0.0 0.6 GO:0005684 U2-type spliceosomal complex(GO:0005684)
0.0 2.7 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 2.8 GO:1990204 oxidoreductase complex(GO:1990204)
0.0 0.7 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.2 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.8 GO:0032420 stereocilium(GO:0032420)
0.0 0.9 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.5 GO:0005581 collagen trimer(GO:0005581)
0.0 0.5 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.2 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 5.8 GO:0005938 cell cortex(GO:0005938)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 4.9 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 1.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.9 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 11.3 GO:0005615 extracellular space(GO:0005615)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.9 2.7 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.9 2.6 GO:0071633 dihydroceramidase activity(GO:0071633)
0.8 4.0 GO:0035174 histone serine kinase activity(GO:0035174)
0.7 2.0 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.6 1.8 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.5 3.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.5 2.5 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.5 2.4 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.4 3.1 GO:0008242 omega peptidase activity(GO:0008242)
0.4 3.0 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.4 3.0 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.4 1.4 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.3 5.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.3 3.5 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.2 1.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.2 1.1 GO:0043532 angiostatin binding(GO:0043532)
0.2 10.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 1.6 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.2 0.9 GO:0035877 death effector domain binding(GO:0035877)
0.2 2.3 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.2 0.6 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.2 3.3 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2 1.6 GO:0050733 RS domain binding(GO:0050733)
0.2 2.5 GO:0016594 glycine binding(GO:0016594)
0.2 1.2 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.2 1.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 1.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 1.1 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.1 0.4 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.1 0.4 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 2.5 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.1 0.9 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1 2.1 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 1.5 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 3.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.5 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 0.8 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.1 1.2 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.1 0.7 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.1 5.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 1.0 GO:0015266 protein channel activity(GO:0015266)
0.1 0.6 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 0.6 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 1.0 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 1.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 1.4 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 2.0 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 0.6 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 1.9 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.2 GO:0050632 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
0.0 1.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.4 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.9 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 2.1 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.6 GO:0005179 hormone activity(GO:0005179)
0.0 0.9 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 1.6 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.5 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.9 GO:0019843 rRNA binding(GO:0019843)
0.0 4.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.8 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 1.4 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.7 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.2 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 1.2 GO:0035254 glutamate receptor binding(GO:0035254)
0.0 0.2 GO:0004112 cyclic-nucleotide phosphodiesterase activity(GO:0004112)
0.0 0.4 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.8 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0031489 myosin V binding(GO:0031489)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 9.3 PID_AURORA_B_PATHWAY Aurora B signaling
0.1 4.1 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 3.3 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.7 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.1 0.9 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 10.5 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.0 PID_BARD1_PATHWAY BARD1 signaling events
0.1 1.5 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.1 1.1 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 2.5 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 2.3 PID_FAS_PATHWAY FAS (CD95) signaling pathway
0.1 0.8 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.0 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.0 1.4 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 0.9 PID_P53_REGULATION_PATHWAY p53 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.4 REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.2 3.6 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.2 5.3 REACTOME_KINESINS Genes involved in Kinesins
0.2 1.8 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.1 3.0 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 2.0 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 3.1 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.1 0.9 REACTOME_ACYL_CHAIN_REMODELLING_OF_PS Genes involved in Acyl chain remodelling of PS
0.1 3.5 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.1 0.9 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 2.6 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 4.4 REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1 1.5 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 0.5 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 1.2 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 3.5 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.7 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.6 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.7 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.4 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 3.1 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 0.6 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.3 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.0 9.6 REACTOME_HEMOSTASIS Genes involved in Hemostasis
0.0 0.6 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.1 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.9 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.2 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.9 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 0.4 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.5 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.2 REACTOME_GAP_JUNCTION_TRAFFICKING Genes involved in Gap junction trafficking
0.0 0.7 REACTOME_G_ALPHA_S_SIGNALLING_EVENTS Genes involved in G alpha (s) signalling events