Motif ID: Tcf7l1

Z-value: 0.913


Transcription factors associated with Tcf7l1:

Gene SymbolEntrez IDGene Name
Tcf7l1 ENSMUSG00000055799.7 Tcf7l1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tcf7l1mm10_v2_chr6_-_72788952_727890610.391.2e-02Click!


Activity profile for motif Tcf7l1.

activity profile for motif Tcf7l1


Sorted Z-values histogram for motif Tcf7l1

Sorted Z-values for motif Tcf7l1



Network of associatons between targets according to the STRING database.



First level regulatory network of Tcf7l1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_108921648 4.471 ENSMUST00000144511.1
Axin2
axin2
chr11_+_108920800 4.405 ENSMUST00000140821.1
Axin2
axin2
chr3_+_131110350 3.317 ENSMUST00000066849.6
ENSMUST00000106341.2
ENSMUST00000029611.7
Lef1


lymphoid enhancer binding factor 1


chr14_+_27039001 3.121 ENSMUST00000035336.3
Il17rd
interleukin 17 receptor D
chr2_+_153031852 2.663 ENSMUST00000037235.6
Xkr7
X Kell blood group precursor related family member 7 homolog
chr1_-_183147461 2.600 ENSMUST00000171366.1
Disp1
dispatched homolog 1 (Drosophila)
chr9_+_85842852 2.482 ENSMUST00000098500.3
Tpbg
trophoblast glycoprotein
chr9_+_35423582 2.353 ENSMUST00000154652.1
Cdon
cell adhesion molecule-related/down-regulated by oncogenes
chr14_-_98169542 2.300 ENSMUST00000069334.7
ENSMUST00000071533.6
Dach1

dachshund 1 (Drosophila)

chr17_-_70851189 2.253 ENSMUST00000059775.8
Tgif1
TGFB-induced factor homeobox 1
chr7_-_115824699 2.244 ENSMUST00000169129.1
Sox6
SRY-box containing gene 6
chr2_+_70474923 2.221 ENSMUST00000100043.2
Sp5
trans-acting transcription factor 5
chr15_+_34238026 2.166 ENSMUST00000022867.3
Laptm4b
lysosomal-associated protein transmembrane 4B
chr7_+_45216671 2.084 ENSMUST00000134420.1
Tead2
TEA domain family member 2
chr4_+_62583568 2.052 ENSMUST00000098031.3
Rgs3
regulator of G-protein signaling 3
chr13_-_102906046 2.008 ENSMUST00000171791.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr5_-_148392810 1.990 ENSMUST00000138257.1
Slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr13_-_102905740 1.868 ENSMUST00000167462.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr7_+_100493795 1.848 ENSMUST00000129324.1
Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr18_-_62756275 1.801 ENSMUST00000067450.1
ENSMUST00000048109.5
2700046A07Rik

RIKEN cDNA 2700046A07 gene

chr5_+_44100442 1.798 ENSMUST00000072800.4
Gm16401
predicted gene 16401
chr18_+_82914632 1.768 ENSMUST00000071233.6
Zfp516
zinc finger protein 516
chr3_-_57575760 1.764 ENSMUST00000029380.7
Wwtr1
WW domain containing transcription regulator 1
chr9_+_119402444 1.746 ENSMUST00000035093.8
ENSMUST00000165044.1
Acvr2b

activin receptor IIB

chr10_+_80150448 1.654 ENSMUST00000153477.1
Midn
midnolin
chr1_+_59482133 1.562 ENSMUST00000114246.2
ENSMUST00000037105.6
Fzd7

frizzled homolog 7 (Drosophila)

chr2_+_173021902 1.556 ENSMUST00000029014.9
Rbm38
RNA binding motif protein 38
chr6_-_148944750 1.528 ENSMUST00000111562.1
ENSMUST00000081956.5
Fam60a

family with sequence similarity 60, member A

chrX_-_134161928 1.487 ENSMUST00000033611.4
Xkrx
X Kell blood group precursor related X linked
chr13_-_54687644 1.459 ENSMUST00000129881.1
Rnf44
ring finger protein 44
chr17_+_3326552 1.452 ENSMUST00000169838.1
Tiam2
T cell lymphoma invasion and metastasis 2
chr17_-_35697971 1.439 ENSMUST00000146472.1
Ddr1
discoidin domain receptor family, member 1
chrX_-_48034842 1.429 ENSMUST00000039026.7
Apln
apelin
chr1_+_158362330 1.426 ENSMUST00000170718.1
Astn1
astrotactin 1
chr8_+_79028587 1.403 ENSMUST00000119254.1
Zfp827
zinc finger protein 827
chr7_-_144939823 1.388 ENSMUST00000093962.4
Ccnd1
cyclin D1
chr6_+_29735667 1.343 ENSMUST00000001812.4
Smo
smoothened homolog (Drosophila)
chr19_-_47919269 1.332 ENSMUST00000095998.5
Itprip
inositol 1,4,5-triphosphate receptor interacting protein
chr19_-_41802028 1.329 ENSMUST00000026150.8
ENSMUST00000177495.1
ENSMUST00000163265.1
Arhgap19


Rho GTPase activating protein 19


chr4_-_126468580 1.319 ENSMUST00000097888.3
Ago1
argonaute RISC catalytic subunit 1
chr2_+_173022360 1.303 ENSMUST00000173997.1
Rbm38
RNA binding motif protein 38
chr4_-_142239356 1.286 ENSMUST00000036476.3
Kazn
kazrin, periplakin interacting protein
chr16_-_34513944 1.265 ENSMUST00000151491.1
ENSMUST00000114960.2
Kalrn

kalirin, RhoGEF kinase

chr12_-_54986363 1.231 ENSMUST00000173433.1
ENSMUST00000173803.1
Baz1a
Gm20403
bromodomain adjacent to zinc finger domain 1A
predicted gene 20403
chr17_+_28691419 1.230 ENSMUST00000124886.1
Mapk14
mitogen-activated protein kinase 14
chr5_+_65131184 1.218 ENSMUST00000031089.5
ENSMUST00000101191.3
Klhl5

kelch-like 5

chr2_+_152081529 1.217 ENSMUST00000064061.3
Scrt2
scratch homolog 2, zinc finger protein (Drosophila)
chr3_-_57575907 1.209 ENSMUST00000120977.1
Wwtr1
WW domain containing transcription regulator 1
chr10_+_80300997 1.164 ENSMUST00000140828.1
ENSMUST00000138909.1
Apc2

adenomatosis polyposis coli 2

chr10_+_80151154 1.143 ENSMUST00000146516.1
ENSMUST00000144526.1
Midn

midnolin

chr19_-_37330613 1.130 ENSMUST00000131070.1
Ide
insulin degrading enzyme
chr16_-_34514084 1.128 ENSMUST00000089655.5
Kalrn
kalirin, RhoGEF kinase
chr7_-_105787544 1.128 ENSMUST00000078482.5
ENSMUST00000154659.1
Dchs1

dachsous 1 (Drosophila)

chr17_+_75005523 1.127 ENSMUST00000001927.5
Ltbp1
latent transforming growth factor beta binding protein 1
chr17_-_89910449 1.123 ENSMUST00000086423.4
Gm10184
predicted pseudogene 10184
chr3_-_25212720 1.123 ENSMUST00000091289.3
Gm10259
predicted pseudogene 10259
chr9_+_21616166 1.109 ENSMUST00000034707.8
ENSMUST00000098948.3
Smarca4

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

chr11_+_108920342 1.103 ENSMUST00000052915.7
Axin2
axin2
chr17_-_47924400 1.065 ENSMUST00000113263.1
ENSMUST00000097311.2
Foxp4

forkhead box P4

chr9_+_110132015 1.061 ENSMUST00000088716.5
ENSMUST00000111969.1
ENSMUST00000035057.7
ENSMUST00000111966.1
ENSMUST00000111968.1
Smarcc1




SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1




chr17_-_47924460 1.060 ENSMUST00000113262.1
Foxp4
forkhead box P4
chr9_+_107569112 1.058 ENSMUST00000010191.7
Hyal2
hyaluronoglucosaminidase 2
chr7_+_127233227 1.034 ENSMUST00000056232.6
Zfp553
zinc finger protein 553
chr9_+_102717668 1.029 ENSMUST00000035121.7
Amotl2
angiomotin-like 2
chr5_-_131538687 1.026 ENSMUST00000161374.1
Auts2
autism susceptibility candidate 2
chr7_-_83884289 1.015 ENSMUST00000094216.3
Mesdc1
mesoderm development candidate 1
chr4_+_132638987 1.009 ENSMUST00000135299.1
ENSMUST00000081726.6
ENSMUST00000180250.1
ENSMUST00000020197.7
ENSMUST00000079157.4
Eya3




eyes absent 3 homolog (Drosophila)




chr10_-_13388830 0.996 ENSMUST00000079698.5
Phactr2
phosphatase and actin regulator 2
chr7_+_127233044 0.961 ENSMUST00000106312.3
Zfp553
zinc finger protein 553
chr7_+_67655414 0.937 ENSMUST00000107470.1
Ttc23
tetratricopeptide repeat domain 23
chr6_+_17065129 0.926 ENSMUST00000115467.4
ENSMUST00000154266.2
ENSMUST00000076654.7
Tes


testis derived transcript


chr11_+_117332335 0.894 ENSMUST00000106349.1
Sept9
septin 9
chr2_+_164823001 0.893 ENSMUST00000132282.1
Zswim1
zinc finger SWIM-type containing 1
chr19_-_5729618 0.879 ENSMUST00000116558.2
ENSMUST00000099955.3
ENSMUST00000161368.1
Fam89b


family with sequence similarity 89, member B


chr11_+_3649759 0.873 ENSMUST00000140242.1
Morc2a
microrchidia 2A
chr5_-_114380459 0.861 ENSMUST00000001125.5
Kctd10
potassium channel tetramerisation domain containing 10
chr3_+_32708546 0.850 ENSMUST00000029214.7
Actl6a
actin-like 6A
chr2_+_35582829 0.824 ENSMUST00000135741.1
Dab2ip
disabled 2 interacting protein
chr6_-_122340499 0.821 ENSMUST00000160843.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr1_+_88227005 0.818 ENSMUST00000061013.6
ENSMUST00000113130.1
Mroh2a

maestro heat-like repeat family member 2A

chr10_-_13388753 0.803 ENSMUST00000105546.1
Phactr2
phosphatase and actin regulator 2
chr15_-_98871175 0.791 ENSMUST00000178486.2
ENSMUST00000023741.9
Kmt2d

lysine (K)-specific methyltransferase 2D

chr2_-_69586021 0.730 ENSMUST00000100051.2
ENSMUST00000092551.4
ENSMUST00000080953.5
Lrp2


low density lipoprotein receptor-related protein 2


chr7_-_105787567 0.729 ENSMUST00000144189.1
Dchs1
dachsous 1 (Drosophila)
chr16_+_4968936 0.727 ENSMUST00000090457.5
4930451G09Rik
RIKEN cDNA 4930451G09 gene
chr6_+_51432678 0.725 ENSMUST00000160133.1
Nfe2l3
nuclear factor, erythroid derived 2, like 3
chr17_+_20570362 0.701 ENSMUST00000095633.3
Gm5145
predicted pseudogene 5145
chr2_+_27079371 0.692 ENSMUST00000091233.6
Adamtsl2
ADAMTS-like 2
chr16_-_17132377 0.691 ENSMUST00000023453.7
Sdf2l1
stromal cell-derived factor 2-like 1
chr6_-_47813512 0.689 ENSMUST00000077290.7
Pdia4
protein disulfide isomerase associated 4
chr7_-_49636847 0.689 ENSMUST00000032717.6
Dbx1
developing brain homeobox 1
chr8_+_79028317 0.684 ENSMUST00000087927.4
ENSMUST00000098614.2
Zfp827

zinc finger protein 827

chr1_-_78968079 0.680 ENSMUST00000049117.5
Gm5830
predicted pseudogene 5830
chr9_-_65021645 0.678 ENSMUST00000036615.5
Ptplad1
protein tyrosine phosphatase-like A domain containing 1
chr5_-_123012874 0.673 ENSMUST00000172729.1
Kdm2b
lysine (K)-specific demethylase 2B
chr17_+_46202740 0.671 ENSMUST00000087031.5
Xpo5
exportin 5
chr2_+_124610573 0.658 ENSMUST00000103239.3
ENSMUST00000103240.2
Sema6d

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D

chr8_+_31111816 0.656 ENSMUST00000046941.7
Rnf122
ring finger protein 122
chr12_+_21111778 0.646 ENSMUST00000050990.9
Asap2
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr14_-_52020698 0.624 ENSMUST00000067549.7
Zfp219
zinc finger protein 219
chr12_+_31265279 0.614 ENSMUST00000002979.8
ENSMUST00000170495.1
Lamb1

laminin B1

chr1_+_132008285 0.608 ENSMUST00000146432.1
Elk4
ELK4, member of ETS oncogene family
chr14_+_50924968 0.594 ENSMUST00000049411.5
ENSMUST00000136753.1
ENSMUST00000154288.1
Apex1


apurinic/apyrimidinic endonuclease 1


chr2_-_165034821 0.589 ENSMUST00000153905.1
ENSMUST00000040381.8
Ncoa5

nuclear receptor coactivator 5

chr2_-_26092149 0.585 ENSMUST00000114159.2
Nacc2
nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
chrX_-_143933089 0.571 ENSMUST00000087313.3
Dcx
doublecortin
chr3_-_127837419 0.565 ENSMUST00000051737.6
Ap1ar
adaptor-related protein complex 1 associated regulatory protein
chr15_-_50890396 0.564 ENSMUST00000185183.1
Trps1
trichorhinophalangeal syndrome I (human)
chr19_-_32466575 0.555 ENSMUST00000078034.3
Rpl9-ps6
ribosomal protein L9, pseudogene 6
chr5_+_148265265 0.553 ENSMUST00000071878.5
Mtus2
microtubule associated tumor suppressor candidate 2
chr7_+_73375494 0.547 ENSMUST00000094312.5
ENSMUST00000119206.1
Rgma

RGM domain family, member A

chr8_+_45507768 0.544 ENSMUST00000067065.7
ENSMUST00000098788.3
ENSMUST00000067107.7
ENSMUST00000171337.2
ENSMUST00000138049.1
ENSMUST00000141039.1
Sorbs2





sorbin and SH3 domain containing 2





chr5_+_110135823 0.544 ENSMUST00000112519.2
ENSMUST00000014812.8
Chfr

checkpoint with forkhead and ring finger domains

chr3_+_53463666 0.538 ENSMUST00000058577.4
Proser1
proline and serine rich 1
chr5_-_114380505 0.536 ENSMUST00000102581.4
Kctd10
potassium channel tetramerisation domain containing 10
chr12_-_98737405 0.527 ENSMUST00000170188.1
Ptpn21
protein tyrosine phosphatase, non-receptor type 21
chr17_-_34031644 0.521 ENSMUST00000171872.1
Slc39a7
solute carrier family 39 (zinc transporter), member 7
chr13_-_41358990 0.519 ENSMUST00000163623.1
Nedd9
neural precursor cell expressed, developmentally down-regulated gene 9
chr13_-_41273977 0.518 ENSMUST00000163881.1
Gm17364
predicted gene, 17364
chr10_+_79988584 0.516 ENSMUST00000004784.4
ENSMUST00000105374.1
Cnn2

calponin 2

chr8_-_69184177 0.510 ENSMUST00000185176.1
Lzts1
leucine zipper, putative tumor suppressor 1
chr17_+_12119274 0.509 ENSMUST00000024594.2
Agpat4
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr2_-_165034770 0.502 ENSMUST00000122070.1
ENSMUST00000121377.1
Ncoa5

nuclear receptor coactivator 5

chr10_+_11609256 0.498 ENSMUST00000052902.7
Gm9797
predicted pseudogene 9797
chr4_+_32983008 0.487 ENSMUST00000098190.3
ENSMUST00000029946.7
Rragd

Ras-related GTP binding D

chr10_-_61979073 0.484 ENSMUST00000105453.1
ENSMUST00000105452.2
ENSMUST00000105454.2
Col13a1


collagen, type XIII, alpha 1


chr12_+_31265234 0.479 ENSMUST00000169088.1
Lamb1
laminin B1
chr12_-_12941827 0.476 ENSMUST00000043396.7
Mycn
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr8_+_92357787 0.474 ENSMUST00000034184.10
Irx5
Iroquois related homeobox 5 (Drosophila)
chr13_-_54687696 0.468 ENSMUST00000177950.1
ENSMUST00000146931.1
Rnf44

ring finger protein 44

chr9_-_66124872 0.464 ENSMUST00000034946.8
Snx1
sorting nexin 1
chr8_-_34146974 0.460 ENSMUST00000033910.8
Leprotl1
leptin receptor overlapping transcript-like 1
chr7_-_118129567 0.456 ENSMUST00000032888.7
Arl6ip1
ADP-ribosylation factor-like 6 interacting protein 1
chr1_-_93101825 0.454 ENSMUST00000112958.2
Kif1a
kinesin family member 1A
chr12_-_83597140 0.451 ENSMUST00000048319.4
Zfyve1
zinc finger, FYVE domain containing 1
chr4_+_85205120 0.450 ENSMUST00000107188.3
Sh3gl2
SH3-domain GRB2-like 2
chr5_-_102069905 0.446 ENSMUST00000053177.7
ENSMUST00000174698.1
Wdfy3

WD repeat and FYVE domain containing 3

chr4_+_107367757 0.441 ENSMUST00000139560.1
Ndc1
NDC1 transmembrane nucleoporin
chr2_+_163658370 0.438 ENSMUST00000164399.1
ENSMUST00000064703.6
ENSMUST00000099105.2
ENSMUST00000152418.1
ENSMUST00000126182.1
ENSMUST00000131228.1
Pkig





protein kinase inhibitor, gamma





chr2_+_157560078 0.435 ENSMUST00000153739.2
ENSMUST00000173595.1
ENSMUST00000109526.1
ENSMUST00000173839.1
ENSMUST00000173041.1
ENSMUST00000173793.1
ENSMUST00000172487.1
ENSMUST00000088484.5
Nnat







neuronatin







chr3_-_89998656 0.432 ENSMUST00000079724.4
Hax1
HCLS1 associated X-1
chr15_-_50889691 0.428 ENSMUST00000165201.2
ENSMUST00000184458.1
Trps1

trichorhinophalangeal syndrome I (human)

chr12_-_22623087 0.422 ENSMUST00000171036.1
Gm17391
predicted gene, 17391
chr8_-_60954726 0.421 ENSMUST00000110302.1
Clcn3
chloride channel 3
chr17_+_34031787 0.414 ENSMUST00000044858.8
Rxrb
retinoid X receptor beta
chr11_-_87074055 0.412 ENSMUST00000020804.7
Gdpd1
glycerophosphodiester phosphodiesterase domain containing 1
chr18_+_24205937 0.409 ENSMUST00000164998.1
Galnt1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1
chr6_+_38918969 0.405 ENSMUST00000003017.6
Tbxas1
thromboxane A synthase 1, platelet
chr11_-_6274830 0.397 ENSMUST00000132147.1
ENSMUST00000004508.6
Tmed4

transmembrane emp24 protein transport domain containing 4

chr2_-_6722187 0.389 ENSMUST00000182657.1
Celf2
CUGBP, Elav-like family member 2
chr1_+_131153175 0.385 ENSMUST00000112446.2
ENSMUST00000068805.7
ENSMUST00000068791.4
Eif2d


eukaryotic translation initiation factor 2D


chr18_-_88894203 0.383 ENSMUST00000123826.1
Socs6
suppressor of cytokine signaling 6
chr13_-_29984219 0.378 ENSMUST00000146092.1
E2f3
E2F transcription factor 3
chr10_-_117063764 0.376 ENSMUST00000047672.7
Cct2
chaperonin containing Tcp1, subunit 2 (beta)
chr1_-_182019927 0.367 ENSMUST00000078719.6
ENSMUST00000111030.3
ENSMUST00000177811.1
ENSMUST00000111024.3
ENSMUST00000111025.2
Enah




enabled homolog (Drosophila)




chr1_+_136467958 0.362 ENSMUST00000047817.6
Kif14
kinesin family member 14
chr1_-_153487639 0.358 ENSMUST00000042141.5
Dhx9
DEAH (Asp-Glu-Ala-His) box polypeptide 9
chr12_-_23968845 0.356 ENSMUST00000171153.1
Gm17330
predicted gene, 17330
chr7_+_126760591 0.352 ENSMUST00000091328.2
Mapk3
mitogen-activated protein kinase 3
chr6_-_122340525 0.348 ENSMUST00000112600.2
Phc1
polyhomeotic-like 1 (Drosophila)
chr8_-_122678072 0.338 ENSMUST00000006525.7
ENSMUST00000064674.6
Cbfa2t3

core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)

chr6_+_54039558 0.335 ENSMUST00000046856.7
Chn2
chimerin (chimaerin) 2
chr18_-_46212595 0.332 ENSMUST00000037011.4
Trim36
tripartite motif-containing 36
chr1_+_110099295 0.330 ENSMUST00000134301.1
Cdh7
cadherin 7, type 2
chr9_+_119444923 0.326 ENSMUST00000035094.6
ENSMUST00000164213.2
Exog

endo/exonuclease (5'-3'), endonuclease G-like

chr12_-_84408991 0.325 ENSMUST00000120942.1
ENSMUST00000110272.2
Entpd5

ectonucleoside triphosphate diphosphohydrolase 5

chr6_-_122340200 0.322 ENSMUST00000159384.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr8_+_86745679 0.322 ENSMUST00000098532.2
Gm10638
predicted gene 10638
chr3_-_95106779 0.321 ENSMUST00000005768.7
ENSMUST00000107232.2
ENSMUST00000107236.2
Pip5k1a


phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha


chr2_+_167932327 0.315 ENSMUST00000029053.7
Ptpn1
protein tyrosine phosphatase, non-receptor type 1
chr14_+_61599493 0.313 ENSMUST00000039562.6
Trim13
tripartite motif-containing 13
chr12_-_21417356 0.309 ENSMUST00000103002.1
Ywhaq
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
chr17_+_34604262 0.302 ENSMUST00000174041.1
Agpat1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr12_-_21417526 0.300 ENSMUST00000049531.9
ENSMUST00000155480.1
Ywhaq

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide

chr17_-_34031684 0.294 ENSMUST00000169397.1
Slc39a7
solute carrier family 39 (zinc transporter), member 7
chr11_+_121237216 0.294 ENSMUST00000103015.3
Narf
nuclear prelamin A recognition factor
chr2_+_160731684 0.291 ENSMUST00000174885.1
ENSMUST00000109462.1
Plcg1

phospholipase C, gamma 1

chr9_-_45984816 0.290 ENSMUST00000172450.1
Pafah1b2
platelet-activating factor acetylhydrolase, isoform 1b, subunit 2
chr12_+_84996309 0.276 ENSMUST00000168977.1
ENSMUST00000021670.8
Ylpm1

YLP motif containing 1

chr4_-_118179628 0.275 ENSMUST00000097911.2
Kdm4a
lysine (K)-specific demethylase 4A
chr10_+_43479140 0.271 ENSMUST00000167488.1
ENSMUST00000040147.7
Bend3

BEN domain containing 3

chr5_-_134946917 0.267 ENSMUST00000051401.2
Cldn4
claudin 4
chr8_+_107436355 0.264 ENSMUST00000166615.1
Wwp2
WW domain containing E3 ubiquitin protein ligase 2
chrX_+_71556874 0.258 ENSMUST00000123100.1
Hmgb3
high mobility group box 3
chr12_-_21417591 0.258 ENSMUST00000135088.1
Ywhaq
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
chr12_+_19954505 0.254 ENSMUST00000179133.1
Gm21863
predicted gene, 21863
chr1_+_161142706 0.249 ENSMUST00000111608.1
ENSMUST00000052245.8
Ankrd45

ankyrin repeat domain 45

chr2_-_180889660 0.247 ENSMUST00000137629.1
Gm14342
predicted gene 14342
chr12_-_24252181 0.246 ENSMUST00000169148.1
Gm9312
predicted gene 9312
chr11_-_78497734 0.241 ENSMUST00000061174.6
Sarm1
sterile alpha and HEAT/Armadillo motif containing 1
chr9_+_90163057 0.241 ENSMUST00000113059.1
ENSMUST00000167122.1
Adamts7

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7

chr19_-_10604258 0.237 ENSMUST00000037678.6
Dak
dihydroxyacetone kinase 2 homolog (yeast)
chr10_-_4387436 0.234 ENSMUST00000100077.3
Zbtb2
zinc finger and BTB domain containing 2
chr6_+_86628174 0.220 ENSMUST00000043400.6
Asprv1
aspartic peptidase, retroviral-like 1
chr17_-_34031544 0.220 ENSMUST00000025186.8
Slc39a7
solute carrier family 39 (zinc transporter), member 7
chr7_-_27195727 0.214 ENSMUST00000163311.2
ENSMUST00000126211.1
Snrpa

small nuclear ribonucleoprotein polypeptide A

chr9_-_99876147 0.210 ENSMUST00000054819.8
Sox14
SRY-box containing gene 14
chr7_-_27196138 0.208 ENSMUST00000122202.1
ENSMUST00000080356.3
Snrpa

small nuclear ribonucleoprotein polypeptide A

chr3_+_19957037 0.208 ENSMUST00000091309.5
ENSMUST00000108329.1
ENSMUST00000003714.6
Cp


ceruloplasmin


chr14_-_70766598 0.207 ENSMUST00000167242.1
ENSMUST00000022696.6
Xpo7

exportin 7


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 10.0 GO:0061181 regulation of chondrocyte development(GO:0061181)
1.1 3.3 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.8 2.3 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.7 1.3 GO:0060242 contact inhibition(GO:0060242)
0.5 1.6 GO:0001705 ectoderm formation(GO:0001705)
0.5 3.0 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.5 1.4 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.5 2.8 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.5 1.9 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.4 1.1 GO:0007403 glial cell fate determination(GO:0007403)
0.3 1.0 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.3 1.2 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.3 2.4 GO:0061368 maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.3 2.4 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.3 0.9 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.3 1.1 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.2 2.6 GO:0060539 diaphragm development(GO:0060539)
0.2 0.7 GO:1903334 positive regulation of protein folding(GO:1903334)
0.2 3.9 GO:0048617 embryonic foregut morphogenesis(GO:0048617)
0.2 2.9 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.2 1.3 GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.2 1.1 GO:0042117 monocyte activation(GO:0042117)
0.2 1.8 GO:1990845 adaptive thermogenesis(GO:1990845)
0.2 2.2 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.2 1.4 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.2 2.1 GO:0048368 lateral mesoderm development(GO:0048368)
0.2 0.7 GO:1900368 regulation of RNA interference(GO:1900368)
0.2 0.8 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.2 1.1 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.1 0.4 GO:0035973 aggrephagy(GO:0035973)
0.1 1.3 GO:0031424 keratinization(GO:0031424)
0.1 0.6 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 2.3 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 0.4 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.1 0.7 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 2.0 GO:0015809 arginine transport(GO:0015809)
0.1 1.0 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 1.5 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 1.4 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 1.1 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.1 1.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 2.2 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.1 0.4 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.1 0.4 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.5 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 0.3 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202) negative regulation of PERK-mediated unfolded protein response(GO:1903898) positive regulation of receptor catabolic process(GO:2000646)
0.1 0.5 GO:0002036 regulation of L-glutamate transport(GO:0002036) endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 1.1 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 0.4 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 0.4 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.1 0.8 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.1 0.4 GO:2000767 interferon-beta secretion(GO:0035546) regulation of interferon-beta secretion(GO:0035547) positive regulation of interferon-beta secretion(GO:0035549) CRD-mediated mRNA stabilization(GO:0070934) positive regulation of cytoplasmic translation(GO:2000767)
0.1 0.4 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.1 0.4 GO:0002741 positive regulation of cytokine secretion involved in immune response(GO:0002741)
0.1 0.7 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.1 0.4 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.5 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.1 0.3 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 0.5 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.1 0.1 GO:0007501 mesodermal cell fate specification(GO:0007501) regulation of mesodermal cell fate specification(GO:0042661) negative regulation of mesodermal cell fate specification(GO:0042662)
0.1 0.3 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 0.4 GO:0032790 ribosome disassembly(GO:0032790)
0.1 0.5 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.1 1.8 GO:0009409 response to cold(GO:0009409)
0.1 0.8 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.1 0.3 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.1 0.9 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.0 0.6 GO:0043247 telomere maintenance in response to DNA damage(GO:0043247)
0.0 0.6 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.5 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.6 GO:0070932 histone H3 deacetylation(GO:0070932)
0.0 0.3 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.9 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 1.3 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.0 1.9 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.7 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.5 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 1.1 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 1.0 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.7 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.0 1.4 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.4 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.4 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 1.0 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0060368 negative regulation of low-density lipoprotein particle clearance(GO:0010989) regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.0 0.9 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.5 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 1.4 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.3 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.5 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.3 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 2.3 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.5 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.7 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.3 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.3 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.4 GO:0034308 primary alcohol metabolic process(GO:0034308)
0.0 0.1 GO:0042711 maternal behavior(GO:0042711)
0.0 0.1 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 0.3 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.5 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.3 GO:0030813 positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.0 0.5 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 0.2 GO:1902475 L-glutamate transmembrane transport(GO:0089711) L-alpha-amino acid transmembrane transport(GO:1902475)
0.0 0.3 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.0 0.2 GO:0046688 response to copper ion(GO:0046688)
0.0 0.5 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.5 GO:0031648 protein destabilization(GO:0031648)
0.0 0.9 GO:0034766 negative regulation of ion transmembrane transport(GO:0034766)
0.0 0.3 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.3 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.0 GO:0038026 reelin-mediated signaling pathway(GO:0038026)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.4 1.1 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.3 1.2 GO:0008623 CHRAC(GO:0008623)
0.3 3.1 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.3 1.1 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.3 1.3 GO:0001533 cornified envelope(GO:0001533)
0.2 2.3 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.2 0.8 GO:1990032 parallel fiber(GO:1990032)
0.2 1.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.2 0.5 GO:0030905 retromer, tubulation complex(GO:0030905)
0.2 0.5 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 1.5 GO:0001739 sex chromatin(GO:0001739)
0.1 0.4 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 1.9 GO:0071564 npBAF complex(GO:0071564)
0.1 1.3 GO:0044294 dendritic growth cone(GO:0044294)
0.1 1.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.5 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 1.2 GO:0016342 catenin complex(GO:0016342)
0.1 0.5 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 1.4 GO:0036038 MKS complex(GO:0036038)
0.1 1.1 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 1.5 GO:0016580 Sin3 complex(GO:0016580)
0.1 0.8 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 0.9 GO:0031105 septin complex(GO:0031105)
0.1 0.3 GO:0097443 sorting endosome(GO:0097443)
0.0 1.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.3 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0033193 Lsd1/2 complex(GO:0033193)
0.0 0.4 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.4 GO:0042581 specific granule(GO:0042581)
0.0 0.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.4 GO:0031143 pseudopodium(GO:0031143)
0.0 8.8 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.4 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.0 GO:1902737 dendritic filopodium(GO:1902737)
0.0 0.7 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.6 GO:0000922 spindle pole(GO:0000922)
0.0 0.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.8 GO:0005871 kinesin complex(GO:0005871)
0.0 0.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 5.9 GO:0005813 centrosome(GO:0005813)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.2 GO:0043034 costamere(GO:0043034)
0.0 0.5 GO:0001772 immunological synapse(GO:0001772)
0.0 0.5 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.7 GO:0031526 brush border membrane(GO:0031526)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.6 3.3 GO:0030284 estrogen receptor activity(GO:0030284)
0.5 10.0 GO:0070411 I-SMAD binding(GO:0070411)
0.5 1.8 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.5 1.8 GO:0050436 microfibril binding(GO:0050436)
0.3 2.3 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.3 1.3 GO:0005113 patched binding(GO:0005113)
0.3 1.1 GO:0030292 hyalurononglucosaminidase activity(GO:0004415) protein tyrosine kinase inhibitor activity(GO:0030292)
0.2 2.0 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.2 0.7 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.2 1.2 GO:0051525 NFAT protein binding(GO:0051525)
0.2 0.6 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.2 1.7 GO:0034711 inhibin binding(GO:0034711)
0.2 0.6 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.2 2.5 GO:0015197 peptide transporter activity(GO:0015197)
0.2 1.4 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.4 GO:0019966 interleukin-1 binding(GO:0019966)
0.1 1.1 GO:0043559 insulin binding(GO:0043559)
0.1 1.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 2.3 GO:0070410 co-SMAD binding(GO:0070410)
0.1 0.4 GO:0033680 ATP-dependent DNA/RNA helicase activity(GO:0033680)
0.1 0.8 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.5 GO:1990460 leptin receptor binding(GO:1990460)
0.1 0.7 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.7 GO:0070883 pre-miRNA binding(GO:0070883)
0.1 0.4 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.3 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.1 1.6 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.1 0.4 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 1.1 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.1 2.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.4 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1 1.3 GO:0035198 miRNA binding(GO:0035198)
0.1 1.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.3 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.3 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.1 1.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 0.7 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.1 0.5 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 1.5 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.4 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.9 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:2001069 glycogen binding(GO:2001069)
0.0 0.2 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.9 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 1.9 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.3 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.8 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 1.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.8 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 6.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 2.9 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.3 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.4 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.3 GO:0000182 rDNA binding(GO:0000182)
0.0 0.4 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.9 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.5 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.3 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)
0.0 2.7 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 1.2 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 4.4 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.4 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 1.2 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 2.5 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.3 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.0 GO:0038025 reelin receptor activity(GO:0038025)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 8.6 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.1 4.4 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.1 1.1 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 3.1 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.1 1.4 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 1.1 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.1 1.2 PID_NFKAPPAB_ATYPICAL_PATHWAY Atypical NF-kappaB pathway
0.1 6.3 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 2.1 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.1 1.7 PID_ALK1_PATHWAY ALK1 signaling events
0.1 1.6 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 1.8 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 2.6 PID_FGF_PATHWAY FGF signaling pathway
0.0 0.9 PID_MYC_PATHWAY C-MYC pathway
0.0 1.8 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 2.4 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 0.8 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 1.2 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 0.8 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.6 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.4 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.6 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 2.1 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.5 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.5 PID_BMP_PATHWAY BMP receptor signaling
0.0 0.6 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 0.1 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.0 0.4 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 0.5 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 0.3 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.8 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 1.1 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 3.4 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 1.7 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.1 2.3 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 1.8 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 0.6 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 0.7 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.0 0.4 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 3.0 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 1.0 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 2.9 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.2 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.5 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.4 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.5 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.7 REACTOME_REGULATORY_RNA_PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.5 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.8 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.3 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.3 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.8 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 3.2 REACTOME_SIGNALING_BY_FGFR Genes involved in Signaling by FGFR
0.0 0.1 REACTOME_GAB1_SIGNALOSOME Genes involved in GAB1 signalosome
0.0 1.8 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_ Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.3 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.5 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.4 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions