Motif ID: Nfatc3

Z-value: 1.183


Transcription factors associated with Nfatc3:

Gene SymbolEntrez IDGene Name
Nfatc3 ENSMUSG00000031902.9 Nfatc3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfatc3mm10_v2_chr8_+_106059562_106059623-0.287.2e-02Click!


Activity profile for motif Nfatc3.

activity profile for motif Nfatc3


Sorted Z-values histogram for motif Nfatc3

Sorted Z-values for motif Nfatc3



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfatc3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_23248264 4.894 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr18_-_80713062 3.295 ENSMUST00000170905.1
ENSMUST00000078049.4
Nfatc1

nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1

chr10_+_4611971 3.273 ENSMUST00000105590.1
ENSMUST00000067086.7
Esr1

estrogen receptor 1 (alpha)

chr4_-_97584605 2.626 ENSMUST00000107067.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr14_-_16575456 2.559 ENSMUST00000063750.6
Rarb
retinoic acid receptor, beta
chr4_-_97584612 2.551 ENSMUST00000107068.2
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr6_-_136875794 1.997 ENSMUST00000032342.1
Mgp
matrix Gla protein
chr3_-_86548268 1.867 ENSMUST00000077524.3
Mab21l2
mab-21-like 2 (C. elegans)
chr2_+_3114220 1.819 ENSMUST00000072955.5
Fam171a1
family with sequence similarity 171, member A1
chr11_+_63133068 1.797 ENSMUST00000108700.1
Pmp22
peripheral myelin protein 22
chr5_-_88527841 1.796 ENSMUST00000087033.3
Igj
immunoglobulin joining chain
chr7_-_49636847 1.676 ENSMUST00000032717.6
Dbx1
developing brain homeobox 1
chr2_+_157560078 1.665 ENSMUST00000153739.2
ENSMUST00000173595.1
ENSMUST00000109526.1
ENSMUST00000173839.1
ENSMUST00000173041.1
ENSMUST00000173793.1
ENSMUST00000172487.1
ENSMUST00000088484.5
Nnat







neuronatin







chr3_-_61365951 1.604 ENSMUST00000066298.2
B430305J03Rik
RIKEN cDNA B430305J03 gene
chr3_-_37125943 1.590 ENSMUST00000029275.5
Il2
interleukin 2
chr13_+_31806627 1.519 ENSMUST00000062292.2
Foxc1
forkhead box C1
chr6_+_48841476 1.514 ENSMUST00000101426.4
Tmem176a
transmembrane protein 176A
chr6_+_48841633 1.508 ENSMUST00000168406.1
Tmem176a
transmembrane protein 176A
chr16_-_22161450 1.487 ENSMUST00000115379.1
Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr7_+_100494044 1.459 ENSMUST00000153287.1
Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr17_+_34629533 1.445 ENSMUST00000015620.6
Prrt1
proline-rich transmembrane protein 1
chr13_-_114388057 1.444 ENSMUST00000022286.6
Ndufs4
NADH dehydrogenase (ubiquinone) Fe-S protein 4
chr2_+_35282380 1.439 ENSMUST00000028239.6
Gsn
gelsolin
chr1_-_156204998 1.423 ENSMUST00000015628.3
Fam163a
family with sequence similarity 163, member A
chr16_-_59555752 1.394 ENSMUST00000179383.1
ENSMUST00000044604.8
Crybg3

beta-gamma crystallin domain containing 3

chr6_+_47244359 1.373 ENSMUST00000060839.6
Cntnap2
contactin associated protein-like 2
chr7_+_100493795 1.372 ENSMUST00000129324.1
Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr8_+_84970068 1.363 ENSMUST00000164807.1
Prdx2
peroxiredoxin 2
chr18_+_37020097 1.359 ENSMUST00000047614.1
Pcdha2
protocadherin alpha 2
chr1_+_12718496 1.340 ENSMUST00000088585.3
Sulf1
sulfatase 1
chr19_-_29334646 1.331 ENSMUST00000044143.5
Rln1
relaxin 1
chr11_+_63132569 1.312 ENSMUST00000108701.1
Pmp22
peripheral myelin protein 22
chr7_-_70360593 1.271 ENSMUST00000032768.7
Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr13_+_91461050 1.244 ENSMUST00000004094.8
ENSMUST00000042122.8
Ssbp2

single-stranded DNA binding protein 2

chr7_-_70366735 1.176 ENSMUST00000089565.5
Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr3_-_33083016 1.172 ENSMUST00000078226.3
ENSMUST00000108224.1
Pex5l

peroxisomal biogenesis factor 5-like

chr7_+_46847128 1.167 ENSMUST00000005051.4
Ldha
lactate dehydrogenase A
chr10_+_50895651 1.161 ENSMUST00000020071.3
Sim1
single-minded homolog 1 (Drosophila)
chr7_+_99466004 1.153 ENSMUST00000037359.2
Klhl35
kelch-like 35
chr18_+_37484955 1.134 ENSMUST00000053856.4
Pcdhb17
protocadherin beta 17
chr12_+_37241633 1.128 ENSMUST00000049874.7
Agmo
alkylglycerol monooxygenase
chr3_+_94377432 1.111 ENSMUST00000107292.1
Rorc
RAR-related orphan receptor gamma
chr15_+_44787746 1.099 ENSMUST00000181839.1
2310069G16Rik
RIKEN cDNA 2310069G16 gene
chr7_+_130577334 1.092 ENSMUST00000059145.7
ENSMUST00000084513.4
Tacc2

transforming, acidic coiled-coil containing protein 2

chr8_+_104101625 1.072 ENSMUST00000034339.8
Cdh5
cadherin 5
chr3_+_8509477 1.069 ENSMUST00000029002.7
Stmn2
stathmin-like 2
chr11_+_97415527 1.049 ENSMUST00000121799.1
Arhgap23
Rho GTPase activating protein 23
chr12_-_10900296 1.045 ENSMUST00000085735.2
Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chr7_-_101921175 1.032 ENSMUST00000098236.2
Lrrc51
leucine rich repeat containing 51
chrX_-_23285532 1.030 ENSMUST00000115319.2
Klhl13
kelch-like 13
chr10_+_21993890 0.999 ENSMUST00000092673.4
Sgk1
serum/glucocorticoid regulated kinase 1
chr7_-_45510400 0.976 ENSMUST00000033096.7
Nucb1
nucleobindin 1
chr11_+_70018728 0.974 ENSMUST00000018700.6
ENSMUST00000134376.2
Dlg4

discs, large homolog 4 (Drosophila)

chr10_+_77829467 0.963 ENSMUST00000092368.2
Tspear
thrombospondin type laminin G domain and EAR repeats
chr4_+_43406435 0.954 ENSMUST00000098106.2
ENSMUST00000139198.1
Rusc2

RUN and SH3 domain containing 2

chr9_+_65265173 0.954 ENSMUST00000048762.1
Cilp
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr7_+_99535439 0.945 ENSMUST00000098266.2
ENSMUST00000179755.1
Arrb1

arrestin, beta 1

chr6_+_127446819 0.935 ENSMUST00000112191.1
Parp11
poly (ADP-ribose) polymerase family, member 11
chr17_+_52602700 0.932 ENSMUST00000039366.10
Kcnh8
potassium voltage-gated channel, subfamily H (eag-related), member 8
chr7_-_134232005 0.932 ENSMUST00000134504.1
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr2_+_155751117 0.931 ENSMUST00000029140.5
ENSMUST00000132608.1
Procr

protein C receptor, endothelial

chr7_+_119900099 0.916 ENSMUST00000106516.1
Lyrm1
LYR motif containing 1
chr4_-_129558387 0.913 ENSMUST00000067240.4
Lck
lymphocyte protein tyrosine kinase
chr3_+_142620596 0.904 ENSMUST00000165774.1
Gbp2
guanylate binding protein 2
chr9_+_118478344 0.899 ENSMUST00000035020.8
Eomes
eomesodermin homolog (Xenopus laevis)
chrX_+_161717498 0.896 ENSMUST00000061514.7
Rai2
retinoic acid induced 2
chr16_+_13986596 0.891 ENSMUST00000056521.5
ENSMUST00000118412.1
ENSMUST00000131608.1
2900011O08Rik


RIKEN cDNA 2900011O08 gene


chr4_-_129558355 0.886 ENSMUST00000167288.1
ENSMUST00000134336.1
Lck

lymphocyte protein tyrosine kinase

chr3_+_94377505 0.874 ENSMUST00000098877.2
Rorc
RAR-related orphan receptor gamma
chr8_+_62951195 0.859 ENSMUST00000118003.1
Spock3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3
chr4_-_43523595 0.855 ENSMUST00000107914.3
Tpm2
tropomyosin 2, beta
chr14_-_46788267 0.852 ENSMUST00000015903.4
Cnih1
cornichon homolog 1 (Drosophila)
chr8_-_57962564 0.843 ENSMUST00000098757.3
Galntl6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
chr11_+_108682602 0.835 ENSMUST00000106718.3
ENSMUST00000106715.1
ENSMUST00000106724.3
Cep112


centrosomal protein 112


chr13_-_18031616 0.825 ENSMUST00000099736.2
Vdac3-ps1
voltage-dependent anion channel 3, pseudogene 1
chr5_-_51567717 0.821 ENSMUST00000127135.1
ENSMUST00000151104.1
Ppargc1a

peroxisome proliferative activated receptor, gamma, coactivator 1 alpha

chr10_-_96409038 0.815 ENSMUST00000179683.1
Gm20091
predicted gene, 20091
chr9_+_118478182 0.794 ENSMUST00000111763.1
Eomes
eomesodermin homolog (Xenopus laevis)
chr3_-_152266320 0.790 ENSMUST00000046045.8
Nexn
nexilin
chr11_-_3914664 0.788 ENSMUST00000109995.1
ENSMUST00000051207.1
Slc35e4

solute carrier family 35, member E4

chr11_+_99047311 0.776 ENSMUST00000140772.1
Igfbp4
insulin-like growth factor binding protein 4
chr17_-_70849644 0.766 ENSMUST00000134654.1
ENSMUST00000172229.1
ENSMUST00000127719.1
Tgif1


TGFB-induced factor homeobox 1


chr5_-_124354671 0.761 ENSMUST00000031341.4
Cdk2ap1
CDK2 (cyclin-dependent kinase 2)-associated protein 1
chr2_+_18677002 0.756 ENSMUST00000028071.6
Bmi1
Bmi1 polycomb ring finger oncogene
chr2_+_174415804 0.744 ENSMUST00000109075.1
ENSMUST00000016397.6
Nelfcd

negative elongation factor complex member C/D, Th1l

chr2_-_118549668 0.734 ENSMUST00000090219.6
Bmf
BCL2 modifying factor
chr13_+_44731265 0.728 ENSMUST00000173246.1
Jarid2
jumonji, AT rich interactive domain 2
chr15_+_61985540 0.727 ENSMUST00000159327.1
ENSMUST00000167731.1
Myc

myelocytomatosis oncogene

chr9_+_64235201 0.725 ENSMUST00000039011.3
Uchl4
ubiquitin carboxyl-terminal esterase L4
chrX_-_155216444 0.718 ENSMUST00000026318.8
Sat1
spermidine/spermine N1-acetyl transferase 1
chr5_+_66676098 0.700 ENSMUST00000031131.9
Uchl1
ubiquitin carboxy-terminal hydrolase L1
chrX_+_56963325 0.685 ENSMUST00000096431.3
Gpr112
G protein-coupled receptor 112
chr9_+_54951104 0.683 ENSMUST00000171900.1
Psma4
proteasome (prosome, macropain) subunit, alpha type 4
chr14_+_55559993 0.678 ENSMUST00000117236.1
Dcaf11
DDB1 and CUL4 associated factor 11
chr4_-_108406676 0.677 ENSMUST00000184609.1
Gpx7
glutathione peroxidase 7
chr18_+_37742088 0.670 ENSMUST00000003599.6
Pcdhga9
protocadherin gamma subfamily A, 9
chr4_-_84674989 0.665 ENSMUST00000175800.1
ENSMUST00000176418.1
ENSMUST00000175969.1
ENSMUST00000176370.1
ENSMUST00000176947.1
ENSMUST00000102820.2
ENSMUST00000107198.2
ENSMUST00000175756.1
ENSMUST00000176691.1
Bnc2








basonuclin 2








chr14_+_55560010 0.662 ENSMUST00000147981.1
ENSMUST00000133256.1
Dcaf11

DDB1 and CUL4 associated factor 11

chr6_+_120773633 0.662 ENSMUST00000112682.2
Slc25a18
solute carrier family 25 (mitochondrial carrier), member 18
chr10_+_7667503 0.660 ENSMUST00000040135.8
Nup43
nucleoporin 43
chr16_-_76403673 0.658 ENSMUST00000052867.7
Gm9843
predicted gene 9843
chrX_+_71555918 0.656 ENSMUST00000072699.6
ENSMUST00000114582.2
ENSMUST00000015361.4
ENSMUST00000088874.3
Hmgb3



high mobility group box 3



chr18_-_35722330 0.656 ENSMUST00000133064.1
Ecscr
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr6_-_48840988 0.653 ENSMUST00000164733.1
Tmem176b
transmembrane protein 176B
chr1_+_153652943 0.653 ENSMUST00000041776.5
Rgs8
regulator of G-protein signaling 8
chr6_-_48841373 0.649 ENSMUST00000166247.1
Tmem176b
transmembrane protein 176B
chr10_-_80900749 0.640 ENSMUST00000020440.6
Timm13
translocase of inner mitochondrial membrane 13
chr11_-_76027726 0.632 ENSMUST00000021207.6
Fam101b
family with sequence similarity 101, member B
chr6_-_48841098 0.629 ENSMUST00000101429.4
Tmem176b
transmembrane protein 176B
chr13_+_40859768 0.627 ENSMUST00000110191.2
Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr2_+_61711694 0.626 ENSMUST00000028278.7
Psmd14
proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
chr1_-_4880669 0.613 ENSMUST00000078030.3
Gm6104
predicted gene 6104
chr7_-_110862944 0.612 ENSMUST00000033050.3
Lyve1
lymphatic vessel endothelial hyaluronan receptor 1
chr3_+_51559973 0.611 ENSMUST00000180404.1
5031434O11Rik
RIKEN cDNA 5031434O11 gene
chr16_-_13986855 0.601 ENSMUST00000117803.1
Ifitm7
interferon induced transmembrane protein 7
chr5_-_114273702 0.595 ENSMUST00000144050.1
ENSMUST00000044790.5
Foxn4

forkhead box N4

chr19_-_50030735 0.583 ENSMUST00000071866.1
Rpl13a-ps1
ribosomal protein 13A, pseudogene 1
chr14_+_32856756 0.579 ENSMUST00000053175.5
ENSMUST00000100721.2
Vstm4

V-set and transmembrane domain containing 4

chr11_+_93098404 0.578 ENSMUST00000107859.1
ENSMUST00000042943.6
ENSMUST00000107861.1
ENSMUST00000107858.2
Car10



carbonic anhydrase 10



chr18_-_15151427 0.577 ENSMUST00000025992.6
Kctd1
potassium channel tetramerisation domain containing 1
chr4_-_43523746 0.570 ENSMUST00000150592.1
Tpm2
tropomyosin 2, beta
chr6_+_91684061 0.560 ENSMUST00000032185.7
Slc6a6
solute carrier family 6 (neurotransmitter transporter, taurine), member 6
chr18_-_37997543 0.552 ENSMUST00000042944.7
Arap3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr12_-_86079019 0.547 ENSMUST00000003687.6
Tgfb3
transforming growth factor, beta 3
chr7_+_90426312 0.545 ENSMUST00000061391.7
Ccdc89
coiled-coil domain containing 89
chr6_+_21985903 0.537 ENSMUST00000137437.1
ENSMUST00000115383.2
Cped1

cadherin-like and PC-esterase domain containing 1

chr6_+_18848571 0.508 ENSMUST00000056398.8
Naa38
N(alpha)-acetyltransferase 38, NatC auxiliary subunit
chr6_-_136941694 0.504 ENSMUST00000032344.5
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr17_-_36958437 0.501 ENSMUST00000113669.2
Znrd1
zinc ribbon domain containing, 1
chrX_-_60893430 0.498 ENSMUST00000135107.2
Sox3
SRY-box containing gene 3
chr17_-_36958533 0.497 ENSMUST00000172518.1
Znrd1
zinc ribbon domain containing, 1
chr7_-_83884289 0.496 ENSMUST00000094216.3
Mesdc1
mesoderm development candidate 1
chr3_+_121967822 0.495 ENSMUST00000137089.1
Arhgap29
Rho GTPase activating protein 29
chr2_+_174330006 0.494 ENSMUST00000109085.1
ENSMUST00000109087.1
ENSMUST00000109084.1
Gnas


GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus


chr8_+_25017211 0.491 ENSMUST00000033961.5
Tm2d2
TM2 domain containing 2
chr15_-_79164477 0.490 ENSMUST00000040019.4
Sox10
SRY-box containing gene 10
chr3_-_101836223 0.490 ENSMUST00000061831.4
Mab21l3
mab-21-like 3 (C. elegans)
chr8_-_107403197 0.471 ENSMUST00000003947.8
Nqo1
NAD(P)H dehydrogenase, quinone 1
chr4_-_49593875 0.471 ENSMUST00000151542.1
Tmem246
transmembrane protein 246
chr10_+_83722865 0.464 ENSMUST00000150459.1
1500009L16Rik
RIKEN cDNA 1500009L16 gene
chr1_+_153665274 0.463 ENSMUST00000152114.1
ENSMUST00000111812.1
Rgs8

regulator of G-protein signaling 8

chr7_-_30559600 0.462 ENSMUST00000043975.4
ENSMUST00000156241.1
Lin37

lin-37 homolog (C. elegans)

chr7_-_44306903 0.459 ENSMUST00000004587.9
Clec11a
C-type lectin domain family 11, member a
chr9_-_58158498 0.456 ENSMUST00000168864.2
Islr
immunoglobulin superfamily containing leucine-rich repeat
chr16_-_4559720 0.451 ENSMUST00000005862.7
Tfap4
transcription factor AP4
chr4_+_86575668 0.449 ENSMUST00000091064.6
Rraga
Ras-related GTP binding A
chr1_-_16619437 0.446 ENSMUST00000117146.1
Ube2w
ubiquitin-conjugating enzyme E2W (putative)
chr19_+_24875679 0.446 ENSMUST00000073080.5
Gm10053
predicted gene 10053
chr11_-_120348513 0.445 ENSMUST00000071555.6
Actg1
actin, gamma, cytoplasmic 1
chr1_-_180193475 0.438 ENSMUST00000160482.1
ENSMUST00000170472.1
Adck3

aarF domain containing kinase 3

chr5_+_30853796 0.432 ENSMUST00000126284.1
Mapre3
microtubule-associated protein, RP/EB family, member 3
chr7_-_134232125 0.427 ENSMUST00000127524.1
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr3_-_95995662 0.425 ENSMUST00000123006.1
Plekho1
pleckstrin homology domain containing, family O member 1
chrX_-_143827391 0.424 ENSMUST00000087316.5
Capn6
calpain 6
chr11_-_79530569 0.421 ENSMUST00000103236.3
ENSMUST00000170799.1
ENSMUST00000170422.2
Evi2a

Evi2b
ecotropic viral integration site 2a

ecotropic viral integration site 2b
chr7_+_112023469 0.420 ENSMUST00000106653.2
Usp47
ubiquitin specific peptidase 47
chr9_-_29963112 0.419 ENSMUST00000075069.4
Ntm
neurotrimin
chr8_-_84969740 0.417 ENSMUST00000109736.2
ENSMUST00000140561.1
Rnaseh2a

ribonuclease H2, large subunit

chr3_-_145649970 0.417 ENSMUST00000029846.3
Cyr61
cysteine rich protein 61
chr8_-_41041828 0.416 ENSMUST00000051379.7
Mtus1
mitochondrial tumor suppressor 1
chr9_-_13446753 0.416 ENSMUST00000167906.2
Gm17571
predicted gene, 17571
chr3_-_95995698 0.413 ENSMUST00000130043.1
Plekho1
pleckstrin homology domain containing, family O member 1
chr19_+_6942501 0.413 ENSMUST00000113423.3
Bad
BCL2-associated agonist of cell death
chr9_+_34486125 0.409 ENSMUST00000115148.2
ENSMUST00000183580.1
Kirrel3
RP24-225I21.1
kin of IRRE like 3 (Drosophila)
RP24-225I21.1
chr3_-_88461182 0.407 ENSMUST00000166237.1
Sema4a
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr1_+_171437535 0.403 ENSMUST00000043839.4
F11r
F11 receptor
chr8_+_70527724 0.403 ENSMUST00000119353.2
ENSMUST00000075491.7
Fkbp8

FK506 binding protein 8

chr17_-_70851710 0.403 ENSMUST00000166395.2
Tgif1
TGFB-induced factor homeobox 1
chr5_-_23616528 0.401 ENSMUST00000088392.4
Srpk2
serine/arginine-rich protein specific kinase 2
chr3_-_95995999 0.398 ENSMUST00000015889.3
Plekho1
pleckstrin homology domain containing, family O member 1
chr3_+_95526777 0.396 ENSMUST00000015667.2
ENSMUST00000116304.2
Ctss

cathepsin S

chr3_+_138143799 0.388 ENSMUST00000159622.1
Trmt10a
tRNA methyltransferase 10A
chr4_-_133872304 0.388 ENSMUST00000157067.2
Rps6ka1
ribosomal protein S6 kinase polypeptide 1
chr2_-_25608447 0.384 ENSMUST00000058137.8
Rabl6
RAB, member of RAS oncogene family-like 6
chr4_-_11965699 0.380 ENSMUST00000108301.1
ENSMUST00000095144.3
ENSMUST00000108302.1
Pdp1


pyruvate dehyrogenase phosphatase catalytic subunit 1


chr16_-_94370647 0.377 ENSMUST00000113910.1
Pigp
phosphatidylinositol glycan anchor biosynthesis, class P
chr1_-_87156127 0.373 ENSMUST00000160810.1
Ecel1
endothelin converting enzyme-like 1
chr13_+_67863324 0.373 ENSMUST00000078471.5
BC048507
cDNA sequence BC048507
chr13_+_43370710 0.372 ENSMUST00000066804.4
Sirt5
sirtuin 5
chr3_-_116662643 0.371 ENSMUST00000029570.5
Hiat1
hippocampus abundant gene transcript 1
chr19_-_53589067 0.370 ENSMUST00000095978.3
Nutf2-ps1
nuclear transport factor 2, pseudogene 1
chr15_+_41830921 0.368 ENSMUST00000166917.1
Oxr1
oxidation resistance 1
chr1_-_16619245 0.365 ENSMUST00000182984.1
ENSMUST00000182554.1
Ube2w

ubiquitin-conjugating enzyme E2W (putative)

chr7_-_30559828 0.364 ENSMUST00000108164.1
Lin37
lin-37 homolog (C. elegans)
chr11_+_60140066 0.362 ENSMUST00000171108.1
ENSMUST00000090806.4
Rai1

retinoic acid induced 1

chr1_-_66863265 0.361 ENSMUST00000027153.5
Acadl
acyl-Coenzyme A dehydrogenase, long-chain
chr15_-_91191733 0.359 ENSMUST00000069511.6
Abcd2
ATP-binding cassette, sub-family D (ALD), member 2
chr8_-_46152159 0.358 ENSMUST00000110378.2
Snx25
sorting nexin 25
chr11_+_95666957 0.357 ENSMUST00000125172.1
ENSMUST00000036374.5
Phb

prohibitin

chr15_+_72913357 0.353 ENSMUST00000166418.2
Gm3150
predicted gene 3150
chr7_+_99535652 0.348 ENSMUST00000032995.8
ENSMUST00000162404.1
Arrb1

arrestin, beta 1

chr8_+_3515378 0.348 ENSMUST00000004681.7
ENSMUST00000111070.2
Pnpla6

patatin-like phospholipase domain containing 6

chr2_-_64975762 0.345 ENSMUST00000156765.1
Grb14
growth factor receptor bound protein 14
chr5_+_21543525 0.341 ENSMUST00000035651.4
Lrrc17
leucine rich repeat containing 17
chr8_-_84067283 0.339 ENSMUST00000071067.3
C330011M18Rik
RIKEN cDNA C330011M18 gene
chrX_-_155216338 0.334 ENSMUST00000112551.3
Sat1
spermidine/spermine N1-acetyl transferase 1
chr1_-_175491130 0.330 ENSMUST00000027812.5
Rgs7
regulator of G protein signaling 7
chr7_+_128246812 0.330 ENSMUST00000164710.1
ENSMUST00000070656.5
Tgfb1i1

transforming growth factor beta 1 induced transcript 1

chr5_+_117363513 0.329 ENSMUST00000111959.1
Wsb2
WD repeat and SOCS box-containing 2
chr14_+_115092244 0.327 ENSMUST00000176912.1
ENSMUST00000175665.1
Gpc5

glypican 5


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0060854 patterning of lymph vessels(GO:0060854)
0.8 3.3 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.8 4.9 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.7 5.0 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.6 1.7 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.5 2.6 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.5 1.5 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256) response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
0.5 2.4 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.5 1.4 GO:1903903 striated muscle atrophy(GO:0014891) positive regulation of keratinocyte apoptotic process(GO:1902174) regulation of establishment of T cell polarity(GO:1903903)
0.5 1.8 GO:2000319 negative regulation of T-helper 17 type immune response(GO:2000317) regulation of T-helper 17 cell differentiation(GO:2000319) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.4 1.1 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.4 1.1 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.3 1.3 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.3 1.3 GO:0010749 regulation of nitric oxide mediated signal transduction(GO:0010749)
0.3 2.8 GO:1990845 adaptive thermogenesis(GO:1990845)
0.3 0.9 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.3 3.8 GO:0046643 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.3 1.4 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.3 0.8 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.2 1.2 GO:0019659 fermentation(GO:0006113) lactate biosynthetic process from pyruvate(GO:0019244) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.2 1.3 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.2 0.8 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.2 0.5 GO:0003032 detection of oxygen(GO:0003032) negative regulation of macrophage cytokine production(GO:0010936)
0.2 0.7 GO:0044330 canonical Wnt signaling pathway involved in positive regulation of wound healing(GO:0044330) lactic acid secretion(GO:0046722) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.2 1.1 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.2 0.7 GO:0007412 axon target recognition(GO:0007412)
0.2 1.2 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.2 1.0 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.2 3.1 GO:0032060 bleb assembly(GO:0032060)
0.1 0.4 GO:0072554 arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) blood vessel lumenization(GO:0072554) blood vessel endothelial cell fate specification(GO:0097101) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of heart induction(GO:1901321) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.1 0.6 GO:0030091 protein repair(GO:0030091)
0.1 0.4 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.1 0.6 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 0.4 GO:1902220 positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902220)
0.1 1.4 GO:0002536 respiratory burst involved in inflammatory response(GO:0002536) negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1 1.0 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.8 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.1 0.8 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 0.7 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.1 0.6 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.6 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.5 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.1 0.3 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.1 2.3 GO:0060579 ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581)
0.1 0.4 GO:1903936 response to diamide(GO:0072737) cellular response to diamide(GO:0072738) cellular response to sodium arsenite(GO:1903936)
0.1 0.4 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 0.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.2 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.1 0.5 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 0.3 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.1 0.3 GO:0070543 response to linoleic acid(GO:0070543)
0.1 0.9 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 1.6 GO:0051451 myoblast migration(GO:0051451)
0.1 1.1 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.8 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1 0.3 GO:0048539 bone marrow development(GO:0048539)
0.1 0.5 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.1 0.3 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.4 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.1 0.7 GO:0048102 autophagic cell death(GO:0048102)
0.1 0.1 GO:0045168 cell-cell signaling involved in cell fate commitment(GO:0045168)
0.1 0.4 GO:0035063 nuclear speck organization(GO:0035063)
0.1 1.2 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 0.3 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 1.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 1.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.2 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
0.1 1.0 GO:0099628 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.1 0.3 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.4 GO:0002922 positive regulation of humoral immune response(GO:0002922) progesterone receptor signaling pathway(GO:0050847)
0.1 1.0 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 0.4 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 0.2 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.1 0.6 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.1 0.3 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 0.2 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.1 0.7 GO:0043586 tongue development(GO:0043586)
0.1 0.4 GO:0070836 caveola assembly(GO:0070836)
0.1 0.4 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 0.9 GO:0044406 adhesion of symbiont to host(GO:0044406)
0.1 0.7 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.4 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.1 0.5 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.2 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.4 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.3 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.6 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.2 GO:0060591 chondroblast differentiation(GO:0060591)
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.7 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.3 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.0 0.4 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 0.4 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.4 GO:0010566 regulation of ketone biosynthetic process(GO:0010566)
0.0 0.4 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0009838 abscission(GO:0009838)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.4 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.8 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 1.4 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.2 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.3 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.0 0.2 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.7 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.4 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.4 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.8 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.5 GO:0050892 intestinal absorption(GO:0050892)
0.0 0.6 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.9 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 0.4 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.7 GO:0021904 dorsal/ventral neural tube patterning(GO:0021904)
0.0 0.1 GO:0006083 acetate metabolic process(GO:0006083)
0.0 0.1 GO:0097298 regulation of nucleus size(GO:0097298)
0.0 0.8 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.3 GO:0006415 translational termination(GO:0006415)
0.0 0.1 GO:0014889 muscle atrophy(GO:0014889)
0.0 0.1 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.0 0.7 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.4 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.8 GO:0060325 face morphogenesis(GO:0060325)
0.0 2.8 GO:0051028 mRNA transport(GO:0051028)
0.0 0.3 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.1 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.0 0.6 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.2 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.0 0.3 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 1.3 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.2 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.1 GO:0019087 transformation of host cell by virus(GO:0019087)
0.0 0.4 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.4 GO:0045116 protein neddylation(GO:0045116)
0.0 0.0 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 0.1 GO:0072318 clathrin coat disassembly(GO:0072318)
0.0 0.7 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 0.4 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.4 GO:0003016 respiratory system process(GO:0003016)
0.0 0.4 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 1.0 GO:0072164 ureteric bud development(GO:0001657) mesonephric epithelium development(GO:0072163) mesonephric tubule development(GO:0072164)
0.0 0.2 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.3 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.3 1.2 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.2 1.6 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.2 1.0 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.2 0.7 GO:0032021 NELF complex(GO:0032021)
0.2 0.5 GO:0031417 NatC complex(GO:0031417)
0.2 1.4 GO:0030478 actin cap(GO:0030478)
0.1 0.6 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 3.1 GO:0043218 compact myelin(GO:0043218)
0.1 2.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 1.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.8 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 0.4 GO:1990131 Iml1 complex(GO:1990130) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 1.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 1.3 GO:0031143 pseudopodium(GO:0031143)
0.1 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.9 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.1 0.4 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 0.7 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 1.7 GO:0000242 pericentriolar material(GO:0000242)
0.1 1.0 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.7 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 0.6 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.3 GO:0042382 paraspeckles(GO:0042382)
0.0 2.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 1.4 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 1.4 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.1 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.8 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.1 GO:0031982 vesicle(GO:0031982)
0.0 0.3 GO:0044292 dendrite terminus(GO:0044292)
0.0 0.8 GO:0032420 stereocilium(GO:0032420)
0.0 0.7 GO:0031941 filamentous actin(GO:0031941)
0.0 0.4 GO:0001741 XY body(GO:0001741)
0.0 0.8 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.1 GO:0090543 Flemming body(GO:0090543)
0.0 0.2 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.3 GO:0005581 collagen trimer(GO:0005581)
0.0 0.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.8 GO:0005643 nuclear pore(GO:0005643)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 1.0 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 2.0 GO:0043209 myelin sheath(GO:0043209)
0.0 0.3 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 3.8 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.2 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.6 GO:0000792 heterochromatin(GO:0000792)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
1.1 3.3 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.7 2.8 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.5 2.0 GO:0008142 oxysterol binding(GO:0008142)
0.4 1.3 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.4 1.8 GO:0042610 CD8 receptor binding(GO:0042610)
0.4 1.1 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.3 1.6 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.3 1.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.3 1.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 1.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.2 0.6 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.2 2.6 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.2 2.4 GO:0001972 retinoic acid binding(GO:0001972)
0.2 0.7 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.2 0.7 GO:0004096 catalase activity(GO:0004096)
0.2 1.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 0.5 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 1.4 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 0.8 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 1.0 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 1.0 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 0.4 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.1 0.5 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 1.5 GO:0008301 DNA binding, bending(GO:0008301)
0.1 0.4 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.1 0.6 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.3 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.1 0.3 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.4 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.4 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1 0.4 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 0.5 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 0.3 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.3 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.6 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 1.0 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 1.7 GO:0008432 JUN kinase binding(GO:0008432)
0.1 2.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.4 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 2.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.2 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 1.5 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 2.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.2 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 2.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 1.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.3 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 0.7 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.4 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.6 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.0 0.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.3 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.2 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.0 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.7 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.6 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.4 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.3 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.7 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0036122 BMP binding(GO:0036122)
0.0 0.2 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 1.8 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.4 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.3 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.4 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.8 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.1 GO:0001179 RNA polymerase I transcription factor binding(GO:0001179) inward rectifier potassium channel inhibitor activity(GO:0070320)
0.0 1.1 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.1 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0 0.7 GO:0043394 proteoglycan binding(GO:0043394)
0.0 0.9 GO:0070888 E-box binding(GO:0070888)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 1.4 GO:0017022 myosin binding(GO:0017022)
0.0 0.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.9 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.1 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.2 GO:0010181 FMN binding(GO:0010181)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.3 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.4 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.2 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.1 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 0.2 GO:0070412 R-SMAD binding(GO:0070412)
0.0 1.1 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.9 GO:0004872 receptor activity(GO:0004872) molecular transducer activity(GO:0060089)
0.0 0.1 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768)
0.0 0.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 1.0 GO:0035326 enhancer binding(GO:0035326)
0.0 0.4 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.7 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 2.1 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.6 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.3 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 4.0 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.1 2.4 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.1 2.3 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.1 1.6 PID_IL27_PATHWAY IL27-mediated signaling events
0.1 0.8 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.1 2.5 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 3.1 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.1 2.8 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 1.1 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.0 1.4 PID_AVB3_OPN_PATHWAY Osteopontin-mediated events
0.0 1.1 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 1.2 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.9 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.0 2.7 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 2.4 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 1.0 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 2.0 ST_FAS_SIGNALING_PATHWAY Fas Signaling Pathway
0.0 1.0 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.8 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 1.0 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 1.9 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.2 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.0 0.3 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.2 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.5 PID_NFAT_3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.4 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.6 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 PID_IL2_1PATHWAY IL2-mediated signaling events
0.0 0.4 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.0 1.8 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.9 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.1 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.5 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.2 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.2 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.8 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 0.4 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 3.3 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 1.5 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism
0.1 1.1 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.4 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 0.6 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 0.6 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.4 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.9 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.8 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.3 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 4.3 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_ Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 3.6 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.8 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.0 1.1 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.3 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.3 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 1.8 REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 1.1 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.4 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.9 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.4 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.4 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.1 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.0 0.5 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.2 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.4 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.4 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.0 0.5 REACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.4 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.0 0.6 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.2 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 2.6 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.1 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.3 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.2 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.0 1.4 REACTOME_SIGNALING_BY_EGFR_IN_CANCER Genes involved in Signaling by EGFR in Cancer