Motif ID: Fos

Z-value: 0.914


Transcription factors associated with Fos:

Gene SymbolEntrez IDGene Name
Fos ENSMUSG00000021250.7 Fos

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Fosmm10_v2_chr12_+_85473883_85473896-0.095.8e-01Click!


Activity profile for motif Fos.

activity profile for motif Fos


Sorted Z-values histogram for motif Fos

Sorted Z-values for motif Fos



Network of associatons between targets according to the STRING database.



First level regulatory network of Fos

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_13573927 11.493 ENSMUST00000141365.1
ENSMUST00000028062.2
Vim

vimentin

chr2_+_20737306 10.357 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4

enhancer trap locus 4

chr2_+_30078584 6.553 ENSMUST00000045246.7
Pkn3
protein kinase N3
chr18_+_82910863 6.259 ENSMUST00000171238.1
Zfp516
zinc finger protein 516
chr13_+_15463837 6.086 ENSMUST00000110510.3
Gli3
GLI-Kruppel family member GLI3
chr7_+_19083842 5.937 ENSMUST00000032568.7
ENSMUST00000122999.1
ENSMUST00000108473.3
ENSMUST00000108474.1
Dmpk



dystrophia myotonica-protein kinase



chr16_-_44558864 5.816 ENSMUST00000023370.4
Boc
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr10_-_42583628 5.425 ENSMUST00000019938.4
Nr2e1
nuclear receptor subfamily 2, group E, member 1
chr16_-_44558879 5.311 ENSMUST00000114634.1
Boc
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr9_+_78615501 5.186 ENSMUST00000093812.4
Cd109
CD109 antigen
chr19_+_36409719 4.762 ENSMUST00000062389.5
Pcgf5
polycomb group ring finger 5
chr10_+_88091070 4.471 ENSMUST00000048621.7
Pmch
pro-melanin-concentrating hormone
chr7_-_126799163 4.409 ENSMUST00000032934.5
Aldoa
aldolase A, fructose-bisphosphate
chr1_+_107511489 4.286 ENSMUST00000064916.2
Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr7_-_126799134 4.255 ENSMUST00000087566.4
Aldoa
aldolase A, fructose-bisphosphate
chr1_+_107511416 4.196 ENSMUST00000009356.4
Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr6_+_135362931 4.135 ENSMUST00000032330.9
Emp1
epithelial membrane protein 1
chr2_+_167777467 3.969 ENSMUST00000139927.1
ENSMUST00000127441.1
Gm14321

predicted gene 14321

chr9_+_69453620 3.824 ENSMUST00000034756.8
ENSMUST00000123470.1
Anxa2

annexin A2

chr15_-_103366763 3.791 ENSMUST00000023128.6
Itga5
integrin alpha 5 (fibronectin receptor alpha)
chr2_-_101797650 3.755 ENSMUST00000141814.1
ENSMUST00000171088.1
ENSMUST00000043845.7
Prr5l


proline rich 5 like


chr6_+_53573364 3.710 ENSMUST00000047450.7
Creb5
cAMP responsive element binding protein 5
chr2_+_91257323 3.595 ENSMUST00000111349.2
ENSMUST00000131711.1
Pacsin3

protein kinase C and casein kinase substrate in neurons 3

chr17_+_35049966 3.518 ENSMUST00000007257.9
Clic1
chloride intracellular channel 1
chrX_+_96455359 3.504 ENSMUST00000033553.7
Heph
hephaestin
chr2_-_26092149 3.495 ENSMUST00000114159.2
Nacc2
nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
chr13_-_56296551 3.423 ENSMUST00000021970.9
Cxcl14
chemokine (C-X-C motif) ligand 14
chr8_-_61591130 3.418 ENSMUST00000135439.1
ENSMUST00000121200.1
Palld

palladin, cytoskeletal associated protein

chr17_+_78508063 3.386 ENSMUST00000024880.9
Vit
vitrin
chr5_+_42067960 3.367 ENSMUST00000087332.4
Gm16223
predicted gene 16223
chr2_+_52038005 3.231 ENSMUST00000065927.5
Tnfaip6
tumor necrosis factor alpha induced protein 6
chr2_-_36105271 3.228 ENSMUST00000112960.1
ENSMUST00000112967.5
ENSMUST00000112963.1
Lhx6


LIM homeobox protein 6


chr18_+_35118880 3.065 ENSMUST00000042345.6
Ctnna1
catenin (cadherin associated protein), alpha 1
chr12_+_108334341 2.995 ENSMUST00000021684.4
Cyp46a1
cytochrome P450, family 46, subfamily a, polypeptide 1
chr7_+_128523576 2.927 ENSMUST00000033136.7
Bag3
BCL2-associated athanogene 3
chr6_+_7555053 2.840 ENSMUST00000090679.2
ENSMUST00000184986.1
Tac1

tachykinin 1

chr13_-_21780616 2.836 ENSMUST00000080511.2
Hist1h1b
histone cluster 1, H1b
chr10_+_26772477 2.810 ENSMUST00000039557.7
Arhgap18
Rho GTPase activating protein 18
chr3_+_95232287 2.716 ENSMUST00000107200.1
ENSMUST00000107199.1
Cdc42se1

CDC42 small effector 1

chr6_+_42349826 2.645 ENSMUST00000070635.6
Zyx
zyxin
chr14_-_12345847 2.594 ENSMUST00000022262.4
Fezf2
Fez family zinc finger 2
chr7_+_27486910 2.588 ENSMUST00000008528.7
Sertad1
SERTA domain containing 1
chr6_+_4755327 2.546 ENSMUST00000176551.1
Peg10
paternally expressed 10
chr15_-_64312636 2.525 ENSMUST00000177083.1
ENSMUST00000177371.1
Asap1

ArfGAP with SH3 domain, ankyrin repeat and PH domain1

chr1_+_109993982 2.446 ENSMUST00000027542.6
Cdh7
cadherin 7, type 2
chr7_+_67647405 2.423 ENSMUST00000032774.8
ENSMUST00000107471.1
Ttc23

tetratricopeptide repeat domain 23

chr19_+_8989277 2.396 ENSMUST00000092955.3
ENSMUST00000092956.2
Ahnak

AHNAK nucleoprotein (desmoyokin)

chr6_+_42350000 2.382 ENSMUST00000164375.1
Zyx
zyxin
chr12_+_80518990 2.344 ENSMUST00000021558.6
Galnt16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr10_+_94550852 2.280 ENSMUST00000148910.1
ENSMUST00000117460.1
Tmcc3

transmembrane and coiled coil domains 3

chr11_-_33843526 2.261 ENSMUST00000065970.5
ENSMUST00000109340.2
Kcnip1

Kv channel-interacting protein 1

chr13_-_23991158 2.247 ENSMUST00000021770.7
Scgn
secretagogin, EF-hand calcium binding protein
chr3_+_121723515 2.189 ENSMUST00000029771.8
F3
coagulation factor III
chr3_+_116878227 2.187 ENSMUST00000040260.6
Frrs1
ferric-chelate reductase 1
chr3_+_95929246 2.159 ENSMUST00000165307.1
ENSMUST00000015893.6
Anp32e

acidic (leucine-rich) nuclear phosphoprotein 32 family, member E

chr2_-_102451792 2.106 ENSMUST00000099678.3
Fjx1
four jointed box 1 (Drosophila)
chr11_-_33843405 2.022 ENSMUST00000101368.2
Kcnip1
Kv channel-interacting protein 1
chr1_+_135232045 2.020 ENSMUST00000110798.3
Gm4204
predicted gene 4204
chr19_-_36736653 2.009 ENSMUST00000087321.2
Ppp1r3c
protein phosphatase 1, regulatory (inhibitor) subunit 3C
chr11_+_117232254 1.994 ENSMUST00000106354.2
Sept9
septin 9
chr3_+_95929325 1.972 ENSMUST00000171368.1
ENSMUST00000168106.1
Anp32e

acidic (leucine-rich) nuclear phosphoprotein 32 family, member E

chr17_+_43953191 1.901 ENSMUST00000044792.4
Rcan2
regulator of calcineurin 2
chr16_+_78930940 1.859 ENSMUST00000114216.1
ENSMUST00000069148.6
ENSMUST00000023568.7
Chodl


chondrolectin


chr7_-_144751968 1.851 ENSMUST00000155175.1
Ano1
anoctamin 1, calcium activated chloride channel
chr2_-_25224653 1.794 ENSMUST00000043584.4
Tubb4b
tubulin, beta 4B class IVB
chr8_+_105373265 1.762 ENSMUST00000160650.1
Plekhg4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr17_+_43952999 1.756 ENSMUST00000177857.1
Rcan2
regulator of calcineurin 2
chrX_-_7671341 1.753 ENSMUST00000033486.5
Plp2
proteolipid protein 2
chr15_+_59648644 1.750 ENSMUST00000118228.1
Trib1
tribbles homolog 1 (Drosophila)
chr1_-_155527083 1.715 ENSMUST00000097531.2
Gm5532
predicted gene 5532
chr10_+_128790903 1.701 ENSMUST00000026411.6
Mmp19
matrix metallopeptidase 19
chr14_-_68124836 1.687 ENSMUST00000111089.1
ENSMUST00000022638.5
Nefm

neurofilament, medium polypeptide

chrY_-_1286563 1.682 ENSMUST00000091190.5
Ddx3y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr10_+_111473186 1.669 ENSMUST00000065917.8
Nap1l1
nucleosome assembly protein 1-like 1
chr11_-_109473598 1.666 ENSMUST00000070152.5
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr7_-_102250086 1.658 ENSMUST00000106923.1
ENSMUST00000098230.4
Rhog

ras homolog gene family, member G

chr11_-_93968293 1.646 ENSMUST00000170303.1
Gm20390
predicted gene 20390
chr11_-_93968242 1.615 ENSMUST00000107844.2
Nme1
NME/NM23 nucleoside diphosphate kinase 1
chr9_-_78480736 1.613 ENSMUST00000156988.1
Eef1a1
eukaryotic translation elongation factor 1 alpha 1
chr5_-_5265224 1.595 ENSMUST00000115450.1
Cdk14
cyclin-dependent kinase 14
chr2_-_38644087 1.557 ENSMUST00000028083.5
Psmb7
proteasome (prosome, macropain) subunit, beta type 7
chr19_+_46305682 1.528 ENSMUST00000111881.2
Nfkb2
nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
chr4_-_140774196 1.519 ENSMUST00000026381.6
Padi4
peptidyl arginine deiminase, type IV
chr12_+_16810940 1.509 ENSMUST00000020908.7
E2f6
E2F transcription factor 6
chr11_+_94327984 1.479 ENSMUST00000107818.2
ENSMUST00000051221.6
Ankrd40

ankyrin repeat domain 40

chr5_-_148552783 1.468 ENSMUST00000079324.7
ENSMUST00000164904.1
Ubl3

ubiquitin-like 3

chr14_+_65968483 1.430 ENSMUST00000022616.6
Clu
clusterin
chr11_+_94328242 1.430 ENSMUST00000021227.5
Ankrd40
ankyrin repeat domain 40
chr16_+_20651652 1.393 ENSMUST00000007212.8
Psmd2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chrX_-_104671048 1.392 ENSMUST00000042070.5
Zdhhc15
zinc finger, DHHC domain containing 15
chrX_-_23266751 1.390 ENSMUST00000115316.2
Klhl13
kelch-like 13
chr11_+_9118070 1.388 ENSMUST00000020677.1
ENSMUST00000101525.2
ENSMUST00000170444.1
Upp1


uridine phosphorylase 1


chr14_-_62454793 1.380 ENSMUST00000128573.1
Gucy1b2
guanylate cyclase 1, soluble, beta 2
chr8_+_69822429 1.373 ENSMUST00000164890.1
ENSMUST00000034325.4
Lpar2

lysophosphatidic acid receptor 2

chr3_+_14641722 1.346 ENSMUST00000029071.8
Car13
carbonic anhydrase 13
chr7_-_126369543 1.337 ENSMUST00000032997.6
Lat
linker for activation of T cells
chr15_+_59648350 1.329 ENSMUST00000067543.6
Trib1
tribbles homolog 1 (Drosophila)
chr12_-_54999102 1.326 ENSMUST00000173529.1
Baz1a
bromodomain adjacent to zinc finger domain 1A
chr6_-_99044414 1.322 ENSMUST00000177507.1
ENSMUST00000123992.1
Foxp1

forkhead box P1

chr5_-_134946917 1.291 ENSMUST00000051401.2
Cldn4
claudin 4
chr14_-_34310503 1.261 ENSMUST00000111917.1
Fam35a
family with sequence similarity 35, member A
chr11_+_107479478 1.255 ENSMUST00000021063.6
ENSMUST00000106752.3
Psmd12

proteasome (prosome, macropain) 26S subunit, non-ATPase, 12

chr7_+_28881656 1.254 ENSMUST00000066880.4
Capn12
calpain 12
chr11_+_107479549 1.244 ENSMUST00000106750.4
Psmd12
proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
chrX_-_143827391 1.232 ENSMUST00000087316.5
Capn6
calpain 6
chr2_+_122028544 1.229 ENSMUST00000028668.7
Eif3j1
eukaryotic translation initiation factor 3, subunit J1
chr14_+_79515618 1.211 ENSMUST00000110835.1
Elf1
E74-like factor 1
chr2_+_30441831 1.199 ENSMUST00000131476.1
Ppp2r4
protein phosphatase 2A, regulatory subunit B (PR 53)
chrX_+_164269371 1.197 ENSMUST00000145412.1
ENSMUST00000033749.7
Pir

pirin

chr11_-_51650813 1.194 ENSMUST00000142721.1
ENSMUST00000156835.1
ENSMUST00000001080.9
N4bp3


NEDD4 binding protein 3


chr18_+_61045139 1.188 ENSMUST00000025522.4
ENSMUST00000115274.1
Pdgfrb

platelet derived growth factor receptor, beta polypeptide

chr3_-_95739544 1.180 ENSMUST00000153026.1
ENSMUST00000123143.1
ENSMUST00000137912.1
ENSMUST00000029753.6
ENSMUST00000131376.1
ENSMUST00000117507.2
ENSMUST00000128885.1
ENSMUST00000147217.1
Ecm1







extracellular matrix protein 1







chr1_+_131962941 1.160 ENSMUST00000177943.1
Slc45a3
solute carrier family 45, member 3
chr19_-_58455903 1.148 ENSMUST00000131877.1
Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr1_+_156035392 1.127 ENSMUST00000111757.3
Tor1aip2
torsin A interacting protein 2
chr1_-_182517447 1.117 ENSMUST00000068505.8
Capn2
calpain 2
chr10_+_97482350 1.104 ENSMUST00000163448.2
Dcn
decorin
chr1_-_171240055 1.085 ENSMUST00000131286.1
Ndufs2
NADH dehydrogenase (ubiquinone) Fe-S protein 2
chr11_-_102365111 1.080 ENSMUST00000006749.9
Slc4a1
solute carrier family 4 (anion exchanger), member 1
chr4_+_152008803 1.070 ENSMUST00000097773.3
Klhl21
kelch-like 21
chr8_+_69902178 1.068 ENSMUST00000050373.5
Tssk6
testis-specific serine kinase 6
chr9_-_32541589 1.040 ENSMUST00000016231.7
Fli1
Friend leukemia integration 1
chr17_-_84682932 1.031 ENSMUST00000066175.3
Abcg5
ATP-binding cassette, sub-family G (WHITE), member 5
chr7_-_45920830 1.026 ENSMUST00000164119.1
Emp3
epithelial membrane protein 3
chr7_-_133782721 1.019 ENSMUST00000063669.1
Dhx32
DEAH (Asp-Glu-Ala-His) box polypeptide 32
chr3_+_89421619 1.015 ENSMUST00000094378.3
ENSMUST00000137793.1
Shc1

src homology 2 domain-containing transforming protein C1

chr11_-_53480178 1.009 ENSMUST00000104955.2
Sowaha
sosondowah ankyrin repeat domain family member A
chr3_-_95042542 1.007 ENSMUST00000117355.1
ENSMUST00000071664.5
ENSMUST00000107237.1
Psmd4


proteasome (prosome, macropain) 26S subunit, non-ATPase, 4


chr17_-_45573253 0.990 ENSMUST00000165127.1
ENSMUST00000166469.1
ENSMUST00000024739.7
Hsp90ab1


heat shock protein 90 alpha (cytosolic), class B member 1


chr11_-_69666062 0.989 ENSMUST00000108654.2
ENSMUST00000018918.5
Cd68

CD68 antigen

chr13_-_55528511 0.982 ENSMUST00000047877.4
Dok3
docking protein 3
chrX_-_48454152 0.952 ENSMUST00000114958.1
Elf4
E74-like factor 4 (ets domain transcription factor)
chr4_-_126256226 0.942 ENSMUST00000122129.1
ENSMUST00000061143.8
ENSMUST00000106132.2
Map7d1


MAP7 domain containing 1


chr7_+_110772604 0.934 ENSMUST00000005829.6
Ampd3
adenosine monophosphate deaminase 3
chr15_-_99705490 0.926 ENSMUST00000163472.2
Gm17349
predicted gene, 17349
chr7_+_24370255 0.920 ENSMUST00000171904.1
Kcnn4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr8_+_36489191 0.917 ENSMUST00000171777.1
6430573F11Rik
RIKEN cDNA 6430573F11 gene
chr13_-_90905321 0.915 ENSMUST00000109541.3
Atp6ap1l
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr11_-_3914664 0.906 ENSMUST00000109995.1
ENSMUST00000051207.1
Slc35e4

solute carrier family 35, member E4

chr12_+_111166536 0.898 ENSMUST00000060274.6
Traf3
TNF receptor-associated factor 3
chr4_-_133602168 0.891 ENSMUST00000057311.3
Sfn
stratifin
chr17_-_35697971 0.881 ENSMUST00000146472.1
Ddr1
discoidin domain receptor family, member 1
chr12_-_85288419 0.845 ENSMUST00000121930.1
Acyp1
acylphosphatase 1, erythrocyte (common) type
chrX_+_71962971 0.839 ENSMUST00000048790.6
Prrg3
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr11_-_79059872 0.824 ENSMUST00000141409.1
Ksr1
kinase suppressor of ras 1
chr7_-_29248375 0.819 ENSMUST00000032808.4
2200002D01Rik
RIKEN cDNA 2200002D01 gene
chr11_-_100135928 0.815 ENSMUST00000107411.2
Krt15
keratin 15
chr12_+_75308308 0.803 ENSMUST00000118602.1
ENSMUST00000118966.1
ENSMUST00000055390.5
Rhoj


ras homolog gene family, member J


chr17_+_35841491 0.798 ENSMUST00000082337.6
Mdc1
mediator of DNA damage checkpoint 1
chr14_+_66635251 0.792 ENSMUST00000159365.1
ENSMUST00000054661.1
ENSMUST00000159068.1
Adra1a


adrenergic receptor, alpha 1a


chr11_+_80428598 0.783 ENSMUST00000173938.1
ENSMUST00000017572.7
Psmd11

proteasome (prosome, macropain) 26S subunit, non-ATPase, 11

chr7_-_114276107 0.770 ENSMUST00000033008.9
Psma1
proteasome (prosome, macropain) subunit, alpha type 1
chr12_+_70974621 0.766 ENSMUST00000160027.1
ENSMUST00000160864.1
Psma3

proteasome (prosome, macropain) subunit, alpha type 3

chr4_+_133130505 0.757 ENSMUST00000084241.5
ENSMUST00000138831.1
Wasf2

WAS protein family, member 2

chr11_+_80383279 0.742 ENSMUST00000165565.1
ENSMUST00000017567.7
Zfp207

zinc finger protein 207

chr3_-_10208569 0.735 ENSMUST00000029041.4
Fabp4
fatty acid binding protein 4, adipocyte
chr1_+_64690443 0.726 ENSMUST00000114077.1
Ccnyl1
cyclin Y-like 1
chr11_+_80383397 0.698 ENSMUST00000053740.8
Zfp207
zinc finger protein 207
chr5_+_30013141 0.691 ENSMUST00000026845.7
Il6
interleukin 6
chr19_+_33822908 0.686 ENSMUST00000042061.6
Gm5519
predicted pseudogene 5519
chr14_-_55758458 0.676 ENSMUST00000001497.7
Cideb
cell death-inducing DNA fragmentation factor, alpha subunit-like effector B
chr12_-_84194007 0.660 ENSMUST00000110294.1
Elmsan1
ELM2 and Myb/SANT-like domain containing 1
chr8_+_94984399 0.659 ENSMUST00000093271.6
Gpr56
G protein-coupled receptor 56
chr17_-_34628380 0.654 ENSMUST00000167097.2
Ppt2
palmitoyl-protein thioesterase 2
chr2_+_61711694 0.645 ENSMUST00000028278.7
Psmd14
proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
chr8_-_107588392 0.643 ENSMUST00000044106.4
Psmd7
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
chr10_+_80930071 0.640 ENSMUST00000015456.8
Gadd45b
growth arrest and DNA-damage-inducible 45 beta
chr5_-_21785115 0.633 ENSMUST00000115193.1
ENSMUST00000115192.1
ENSMUST00000115195.1
ENSMUST00000030771.5
Dnajc2



DnaJ (Hsp40) homolog, subfamily C, member 2



chr7_-_44816586 0.623 ENSMUST00000047356.8
Atf5
activating transcription factor 5
chr19_+_5050807 0.617 ENSMUST00000025818.6
Rin1
Ras and Rab interactor 1
chr17_+_12119274 0.616 ENSMUST00000024594.2
Agpat4
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr18_-_34954302 0.616 ENSMUST00000025217.8
Hspa9
heat shock protein 9
chr2_-_151632471 0.612 ENSMUST00000137936.1
ENSMUST00000146172.1
ENSMUST00000094456.3
ENSMUST00000148755.1
ENSMUST00000109875.1
ENSMUST00000028951.7
ENSMUST00000109877.3
Snph






syntaphilin






chr14_+_34310727 0.606 ENSMUST00000022322.9
Glud1
glutamate dehydrogenase 1
chr1_-_156034800 0.602 ENSMUST00000169241.1
Tor1aip1
torsin A interacting protein 1
chr11_-_69880971 0.599 ENSMUST00000050555.3
Kctd11
potassium channel tetramerisation domain containing 11
chr16_+_20548577 0.585 ENSMUST00000003319.5
Abcf3
ATP-binding cassette, sub-family F (GCN20), member 3
chr1_+_86064619 0.575 ENSMUST00000027432.8
Psmd1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr18_-_43477764 0.574 ENSMUST00000057110.9
Eif3j2
eukaryotic translation initiation factor 3, subunit J2
chr16_+_90220742 0.565 ENSMUST00000023707.9
Sod1
superoxide dismutase 1, soluble
chr1_-_156034826 0.565 ENSMUST00000141878.1
ENSMUST00000123705.1
Tor1aip1

torsin A interacting protein 1

chr11_-_76509419 0.564 ENSMUST00000094012.4
Abr
active BCR-related gene
chr15_+_80255184 0.561 ENSMUST00000109605.3
Atf4
activating transcription factor 4
chr13_+_93304066 0.560 ENSMUST00000109493.1
Homer1
homer homolog 1 (Drosophila)
chr11_-_84067063 0.544 ENSMUST00000108101.1
Dusp14
dual specificity phosphatase 14
chr9_+_114978507 0.544 ENSMUST00000183104.1
Osbpl10
oxysterol binding protein-like 10
chr7_+_127244511 0.533 ENSMUST00000052509.4
Zfp771
zinc finger protein 771
chr12_+_76370266 0.533 ENSMUST00000042779.3
Zbtb1
zinc finger and BTB domain containing 1
chr7_+_120917744 0.520 ENSMUST00000033173.7
ENSMUST00000106483.2
Polr3e

polymerase (RNA) III (DNA directed) polypeptide E

chr17_-_47834682 0.520 ENSMUST00000066368.6
Mdfi
MyoD family inhibitor
chr7_-_105482197 0.519 ENSMUST00000047040.2
Prkcdbp
protein kinase C, delta binding protein
chr6_-_71632897 0.492 ENSMUST00000065509.4
Kdm3a
lysine (K)-specific demethylase 3A
chr11_-_84069179 0.483 ENSMUST00000138208.1
Dusp14
dual specificity phosphatase 14
chr10_-_64090265 0.480 ENSMUST00000105439.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr17_+_75178911 0.471 ENSMUST00000112514.1
Ltbp1
latent transforming growth factor beta binding protein 1
chr4_-_141723401 0.465 ENSMUST00000177592.1
ENSMUST00000102484.4
Rsc1a1
Ddi2
regulatory solute carrier protein, family 1, member 1
DNA-damage inducible protein 2
chr17_-_32284088 0.456 ENSMUST00000119123.1
ENSMUST00000003726.8
ENSMUST00000121285.1
ENSMUST00000120276.1
ENSMUST00000114475.2
Brd4




bromodomain containing 4




chr17_-_34628005 0.431 ENSMUST00000166040.2
Ppt2
palmitoyl-protein thioesterase 2
chr17_+_75178797 0.423 ENSMUST00000112516.1
ENSMUST00000135447.1
Ltbp1

latent transforming growth factor beta binding protein 1

chr13_-_58215615 0.417 ENSMUST00000058735.5
ENSMUST00000076454.6
Ubqln1

ubiquilin 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 11.5 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
2.0 6.1 GO:0060364 frontal suture morphogenesis(GO:0060364)
1.5 6.0 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
1.5 4.5 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
1.1 3.4 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
1.1 5.4 GO:0021764 amygdala development(GO:0021764)
1.1 1.1 GO:0035092 sperm chromatin condensation(GO:0035092)
1.0 5.2 GO:0072675 osteoclast fusion(GO:0072675)
1.0 3.1 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
1.0 5.8 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.9 2.8 GO:2000851 corticosterone secretion(GO:0035934) positive regulation of glucocorticoid secretion(GO:2000851) regulation of corticosterone secretion(GO:2000852)
0.9 8.7 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.8 3.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.8 3.8 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.7 2.2 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.6 1.2 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.6 1.7 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.5 2.5 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.5 1.4 GO:0046133 pyrimidine ribonucleoside catabolic process(GO:0046133)
0.4 11.1 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.4 1.2 GO:0035441 cell migration involved in vasculogenesis(GO:0035441) metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
0.4 1.2 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.4 3.8 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.4 1.9 GO:0015705 iodide transport(GO:0015705)
0.4 1.1 GO:0097278 transforming growth factor beta activation(GO:0036363) complement-dependent cytotoxicity(GO:0097278)
0.3 3.1 GO:0038203 TORC2 signaling(GO:0038203)
0.3 1.0 GO:0030300 regulation of intestinal cholesterol absorption(GO:0030300) negative regulation of intestinal absorption(GO:1904479)
0.3 2.9 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.3 0.8 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.3 3.5 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.3 0.8 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978)
0.3 5.2 GO:0032060 bleb assembly(GO:0032060)
0.2 1.4 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.2 1.0 GO:0001787 natural killer cell proliferation(GO:0001787)
0.2 0.7 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.2 4.3 GO:0003334 keratinocyte development(GO:0003334)
0.2 7.0 GO:0050873 brown fat cell differentiation(GO:0050873)
0.2 3.7 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.2 1.0 GO:1990839 response to endothelin(GO:1990839)
0.2 0.6 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.2 1.1 GO:0016540 protein autoprocessing(GO:0016540)
0.2 3.6 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.2 4.1 GO:0043486 histone exchange(GO:0043486)
0.2 1.6 GO:0006228 UTP biosynthetic process(GO:0006228)
0.2 0.4 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.2 2.9 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.2 1.5 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.2 1.1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2 0.6 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.1 3.5 GO:0006825 copper ion transport(GO:0006825)
0.1 0.4 GO:0035973 aggrephagy(GO:0035973)
0.1 0.9 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.1 0.5 GO:0002572 pro-T cell differentiation(GO:0002572)
0.1 1.3 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 2.0 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.6 GO:0006538 glutamate catabolic process(GO:0006538)
0.1 0.6 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.1 1.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 0.9 GO:0046541 saliva secretion(GO:0046541)
0.1 0.6 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.6 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.1 1.8 GO:0043248 proteasome assembly(GO:0043248)
0.1 1.3 GO:0006968 cellular defense response(GO:0006968)
0.1 1.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.2 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.1 0.3 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.1 2.1 GO:0045760 positive regulation of action potential(GO:0045760)
0.1 0.8 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 1.2 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.1 0.3 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.1 0.3 GO:0036233 glycine import(GO:0036233)
0.1 0.3 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.1 1.4 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.1 1.1 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.1 0.9 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 0.8 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 0.6 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 1.3 GO:0030574 collagen catabolic process(GO:0030574)
0.1 1.1 GO:0014823 response to activity(GO:0014823)
0.1 2.0 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 1.0 GO:0035855 megakaryocyte development(GO:0035855)
0.1 3.0 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 0.9 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 1.9 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.1 0.5 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.1 0.6 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 2.1 GO:0010842 retina layer formation(GO:0010842)
0.1 2.4 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 0.3 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.1 1.6 GO:1903427 negative regulation of reactive oxygen species biosynthetic process(GO:1903427)
0.0 0.8 GO:0050892 intestinal absorption(GO:0050892)
0.0 1.2 GO:0030224 monocyte differentiation(GO:0030224)
0.0 2.4 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 1.4 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 6.3 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 7.3 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.6 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.3 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.9 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.9 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 0.2 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.8 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 2.5 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 1.5 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.9 GO:0048535 lymph node development(GO:0048535)
0.0 1.1 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.3 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.2 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 1.3 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 3.0 GO:0007179 transforming growth factor beta receptor signaling pathway(GO:0007179)
0.0 1.7 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 2.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.9 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 0.1 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.2 GO:0014029 neural crest formation(GO:0014029)
0.0 1.1 GO:0042775 mitochondrial ATP synthesis coupled electron transport(GO:0042775)
0.0 0.7 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 3.4 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 1.7 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.6 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.6 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.0 1.6 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.8 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 1.7 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.6 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.4 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.0 1.6 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.0 1.4 GO:0000910 cytokinesis(GO:0000910)
0.0 0.6 GO:0045806 negative regulation of endocytosis(GO:0045806)
0.0 1.2 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 1.3 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 0.1 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.0 3.9 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process(GO:0043161)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 11.5 GO:0045098 type III intermediate filament(GO:0045098)
1.3 3.8 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.6 8.7 GO:0035686 sperm fibrous sheath(GO:0035686)
0.5 1.5 GO:1990047 spindle matrix(GO:1990047)
0.4 1.8 GO:0045298 tubulin complex(GO:0045298)
0.4 3.9 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.3 1.3 GO:0008623 CHRAC(GO:0008623)
0.3 1.6 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.3 0.9 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.3 3.1 GO:0005915 zonula adherens(GO:0005915)
0.3 5.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 14.7 GO:0044295 axonal growth cone(GO:0044295)
0.2 3.6 GO:0005838 proteasome regulatory particle(GO:0005838)
0.2 0.7 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.2 2.0 GO:0042587 glycogen granule(GO:0042587)
0.2 1.5 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.2 1.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.2 3.4 GO:0005614 interstitial matrix(GO:0005614)
0.2 1.7 GO:0005883 neurofilament(GO:0005883)
0.2 1.4 GO:0034366 spherical high-density lipoprotein particle(GO:0034366) neurofibrillary tangle(GO:0097418)
0.2 3.1 GO:0031932 TORC2 complex(GO:0031932)
0.2 3.7 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2 1.5 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.2 1.1 GO:0005827 polar microtubule(GO:0005827)
0.1 0.6 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.1 5.6 GO:0016592 mediator complex(GO:0016592)
0.1 5.4 GO:0034707 chloride channel complex(GO:0034707)
0.1 1.6 GO:0005839 proteasome core complex(GO:0005839)
0.1 0.4 GO:0098842 postsynaptic early endosome(GO:0098842)
0.1 1.0 GO:0098533 ATPase dependent transmembrane transport complex(GO:0098533)
0.1 1.8 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 1.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 2.5 GO:0002102 podosome(GO:0002102)
0.1 0.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 1.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 1.1 GO:0031143 pseudopodium(GO:0031143)
0.1 1.1 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 1.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 4.8 GO:0031519 PcG protein complex(GO:0031519)
0.1 0.8 GO:0031209 SCAR complex(GO:0031209)
0.1 1.1 GO:0098644 complex of collagen trimers(GO:0098644)
0.1 6.0 GO:0032587 ruffle membrane(GO:0032587)
0.0 5.0 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.7 GO:0031105 septin complex(GO:0031105)
0.0 4.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.5 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.6 GO:0031045 dense core granule(GO:0031045)
0.0 0.3 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 3.8 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.0 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 3.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.3 GO:0043209 myelin sheath(GO:0043209)
0.0 1.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.1 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 3.6 GO:0044449 contractile fiber part(GO:0044449)
0.0 0.4 GO:0014704 intercalated disc(GO:0014704)
0.0 0.8 GO:0005903 brush border(GO:0005903)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.4 GO:0030496 midbody(GO:0030496)
0.0 0.6 GO:0005876 spindle microtubule(GO:0005876)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 11.3 GO:1990254 keratin filament binding(GO:1990254)
1.4 8.7 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
1.0 3.8 GO:0004859 phospholipase inhibitor activity(GO:0004859) phospholipase A2 inhibitor activity(GO:0019834)
0.7 3.5 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.6 3.7 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.5 1.9 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.4 2.2 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.4 2.4 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.4 1.2 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.4 1.5 GO:0034618 arginine binding(GO:0034618)
0.4 7.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.3 2.9 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.3 5.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.3 3.6 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.3 6.6 GO:0004697 protein kinase C activity(GO:0004697)
0.3 12.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.3 0.8 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.3 1.0 GO:0048408 epidermal growth factor binding(GO:0048408)
0.2 1.2 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.2 1.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.2 0.9 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.2 0.9 GO:0050436 microfibril binding(GO:0050436)
0.2 0.8 GO:0003998 acylphosphatase activity(GO:0003998)
0.2 2.0 GO:0019215 intermediate filament binding(GO:0019215)
0.2 3.4 GO:0017166 vinculin binding(GO:0017166)
0.2 3.1 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.2 1.1 GO:0002135 CTP binding(GO:0002135)
0.2 2.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 0.9 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.2 0.5 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.1 1.8 GO:0019956 chemokine binding(GO:0019956)
0.1 6.3 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 3.0 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 0.6 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 3.1 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.9 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 12.1 GO:0019208 phosphatase regulator activity(GO:0019208)
0.1 1.7 GO:0015643 toxic substance binding(GO:0015643)
0.1 2.1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 1.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 3.4 GO:0008009 chemokine activity(GO:0008009)
0.1 1.1 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.6 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.6 GO:0070728 leucine binding(GO:0070728)
0.1 1.1 GO:0031996 thioesterase binding(GO:0031996)
0.1 1.2 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 0.9 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 1.6 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 0.7 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 1.4 GO:0051787 misfolded protein binding(GO:0051787)
0.1 0.3 GO:0051425 PTB domain binding(GO:0051425)
0.1 3.5 GO:0004407 histone deacetylase activity(GO:0004407)
0.1 3.3 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 4.3 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 1.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 0.6 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.4 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)
0.1 1.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 2.3 GO:0001671 ATPase activator activity(GO:0001671)
0.1 5.0 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 5.4 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 1.0 GO:0017127 cholesterol transporter activity(GO:0017127)
0.1 0.8 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 2.2 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.8 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 1.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.7 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 3.4 GO:0015108 chloride transmembrane transporter activity(GO:0015108)
0.0 0.6 GO:0048038 quinone binding(GO:0048038)
0.0 0.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 1.3 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 2.7 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.1 GO:0031893 vasopressin receptor binding(GO:0031893)
0.0 0.6 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 1.4 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 0.6 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.3 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 1.2 GO:0030332 cyclin binding(GO:0030332)
0.0 0.3 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.5 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.5 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.5 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 3.2 GO:0005539 glycosaminoglycan binding(GO:0005539)
0.0 0.7 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.4 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 1.3 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 1.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.1 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.3 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.8 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 11.1 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.3 12.1 PID_AURORA_B_PATHWAY Aurora B signaling
0.2 6.9 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.2 4.6 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 2.4 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 1.3 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 3.7 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 8.3 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.1 15.4 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 6.1 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 2.5 PID_ARF_3PATHWAY Arf1 pathway
0.1 2.5 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 1.6 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.1 2.0 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 1.7 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 0.4 PID_CXCR4_PATHWAY CXCR4-mediated signaling events
0.0 0.4 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.0 1.4 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.9 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 1.1 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.6 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.0 0.5 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.0 2.5 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.7 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.8 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 3.5 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.4 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.6 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 0.7 PID_ATM_PATHWAY ATM pathway
0.0 0.6 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.7 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.6 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.0 1.1 PID_P73PATHWAY p73 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 11.5 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.4 3.0 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.3 12.1 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.2 10.6 REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.2 2.8 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.2 7.1 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.2 1.4 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.1 2.2 REACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1 1.2 REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION Genes involved in Downstream signal transduction
0.1 1.8 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 2.9 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 1.1 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.1 1.1 REACTOME_ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 0.7 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.1 1.3 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES Genes involved in Generation of second messenger molecules
0.1 4.4 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.1 REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.1 0.8 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 3.5 REACTOME_SIGNAL_TRANSDUCTION_BY_L1 Genes involved in Signal transduction by L1
0.1 0.9 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.1 0.3 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.7 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.1 0.8 REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING Genes involved in SHC1 events in EGFR signaling
0.1 4.1 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.8 REACTOME_LIPID_DIGESTION_MOBILIZATION_AND_TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
0.0 1.2 REACTOME_CELL_CELL_JUNCTION_ORGANIZATION Genes involved in Cell-cell junction organization
0.0 0.7 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 1.4 REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 2.0 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.3 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.5 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 2.0 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 0.6 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 1.1 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 0.6 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.3 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 0.3 REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus