Motif ID: Nkx6-3_Dbx2_Barx2

Z-value: 0.454

Transcription factors associated with Nkx6-3_Dbx2_Barx2:

Gene SymbolEntrez IDGene Name
Barx2 ENSMUSG00000032033.10 Barx2
Dbx2 ENSMUSG00000045608.6 Dbx2
Nkx6-3 ENSMUSG00000063672.6 Nkx6-3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Dbx2mm10_v2_chr15_-_95655960_956559600.362.2e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Nkx6-3_Dbx2_Barx2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_+_80000292 2.778 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr13_+_94083490 2.691 ENSMUST00000156071.1
Lhfpl2
lipoma HMGIC fusion partner-like 2
chr5_-_62766153 1.811 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr16_+_11406618 1.701 ENSMUST00000122168.1
Snx29
sorting nexin 29
chr17_-_81649607 1.542 ENSMUST00000163680.2
ENSMUST00000086538.3
ENSMUST00000163123.1
Slc8a1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr5_-_70842617 1.485 ENSMUST00000031119.1
Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr4_+_118961578 1.311 ENSMUST00000058651.4
Lao1
L-amino acid oxidase 1
chr13_+_83732438 1.292 ENSMUST00000182701.1
C130071C03Rik
RIKEN cDNA C130071C03 gene
chr10_-_110000219 1.197 ENSMUST00000032719.7
Nav3
neuron navigator 3
chr4_+_102589687 1.180 ENSMUST00000097949.4
ENSMUST00000106901.1
Pde4b

phosphodiesterase 4B, cAMP specific

chrX_-_143933089 1.043 ENSMUST00000087313.3
Dcx
doublecortin
chr8_-_21906412 1.042 ENSMUST00000051965.4
Defb11
defensin beta 11
chr3_-_116712644 1.019 ENSMUST00000029569.2
Slc35a3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr11_+_109543694 0.997 ENSMUST00000106696.1
Arsg
arylsulfatase G
chr17_+_26715644 0.977 ENSMUST00000062519.7
ENSMUST00000144221.1
ENSMUST00000142539.1
ENSMUST00000151681.1
Crebrf



CREB3 regulatory factor



chr5_+_144100387 0.953 ENSMUST00000041804.7
Lmtk2
lemur tyrosine kinase 2
chr2_-_160619971 0.947 ENSMUST00000109473.1
Gm14221
predicted gene 14221
chr9_-_15301555 0.938 ENSMUST00000034414.8
4931406C07Rik
RIKEN cDNA 4931406C07 gene
chr6_-_137169710 0.897 ENSMUST00000117919.1
Rerg
RAS-like, estrogen-regulated, growth-inhibitor
chr13_-_105054895 0.848 ENSMUST00000063551.5
Rgs7bp
regulator of G-protein signalling 7 binding protein
chr17_-_45659312 0.832 ENSMUST00000120717.1
Capn11
calpain 11
chr4_-_14621805 0.829 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr5_-_118244861 0.827 ENSMUST00000117177.1
ENSMUST00000133372.1
ENSMUST00000154786.1
ENSMUST00000121369.1
Rnft2



ring finger protein, transmembrane 2



chr13_-_105271039 0.764 ENSMUST00000069686.6
Rnf180
ring finger protein 180
chr4_+_136143497 0.752 ENSMUST00000008016.2
Id3
inhibitor of DNA binding 3
chr15_-_8710734 0.705 ENSMUST00000005493.7
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr15_-_8710409 0.682 ENSMUST00000157065.1
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr14_+_69347587 0.653 ENSMUST00000064831.5
Entpd4
ectonucleoside triphosphate diphosphohydrolase 4
chr7_+_79273201 0.648 ENSMUST00000037315.6
Abhd2
abhydrolase domain containing 2
chr2_-_113829069 0.645 ENSMUST00000024005.7
Scg5
secretogranin V
chr8_+_34054622 0.585 ENSMUST00000149618.1
Gm9951
predicted gene 9951
chrX_-_143933204 0.581 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chr15_-_33687840 0.574 ENSMUST00000042021.3
Tspyl5
testis-specific protein, Y-encoded-like 5
chr8_-_70212251 0.552 ENSMUST00000063788.7
Slc25a42
solute carrier family 25, member 42
chr8_-_70212268 0.549 ENSMUST00000110127.1
Slc25a42
solute carrier family 25, member 42
chr18_+_57468478 0.545 ENSMUST00000091892.2
Ctxn3
cortexin 3
chr7_-_45103747 0.537 ENSMUST00000003512.7
Fcgrt
Fc receptor, IgG, alpha chain transporter
chr3_+_5218516 0.536 ENSMUST00000175866.1
Zfhx4
zinc finger homeodomain 4
chr10_+_23797052 0.509 ENSMUST00000133289.1
Slc18b1
solute carrier family 18, subfamily B, member 1
chr13_+_109926832 0.480 ENSMUST00000117420.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr17_-_36032682 0.479 ENSMUST00000102678.4
H2-T23
histocompatibility 2, T region locus 23
chr5_+_29195983 0.470 ENSMUST00000160888.1
ENSMUST00000159272.1
ENSMUST00000001247.5
ENSMUST00000161398.1
ENSMUST00000160246.1
Rnf32




ring finger protein 32




chr3_+_5218546 0.454 ENSMUST00000026284.6
Zfhx4
zinc finger homeodomain 4
chr15_+_82252397 0.429 ENSMUST00000136948.1
1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr9_+_67840386 0.418 ENSMUST00000077879.5
Vps13c
vacuolar protein sorting 13C (yeast)
chr8_+_40354303 0.408 ENSMUST00000136835.1
Micu3
mitochondrial calcium uptake family, member 3
chr3_+_5218589 0.394 ENSMUST00000177488.1
Zfhx4
zinc finger homeodomain 4
chr4_-_108301045 0.387 ENSMUST00000043616.6
Zyg11b
zyg-ll family member B, cell cycle regulator
chr9_+_113812547 0.376 ENSMUST00000166734.2
ENSMUST00000111838.2
ENSMUST00000163895.2
Clasp2


CLIP associating protein 2


chr7_-_46672537 0.375 ENSMUST00000049298.7
Tph1
tryptophan hydroxylase 1
chr17_-_50094277 0.372 ENSMUST00000113195.1
Rftn1
raftlin lipid raft linker 1
chr2_+_36230426 0.372 ENSMUST00000062069.5
Ptgs1
prostaglandin-endoperoxide synthase 1
chr3_+_94837702 0.341 ENSMUST00000107266.1
ENSMUST00000042402.5
ENSMUST00000107269.1
Pogz


pogo transposable element with ZNF domain


chr2_-_73580288 0.340 ENSMUST00000028515.3
Chrna1
cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
chrX_+_170009892 0.327 ENSMUST00000180251.1
Gm21887
predicted gene, 21887
chr2_+_109917639 0.325 ENSMUST00000046548.7
ENSMUST00000111037.2
Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chr2_-_45112890 0.323 ENSMUST00000076836.6
Zeb2
zinc finger E-box binding homeobox 2
chr4_-_40722307 0.319 ENSMUST00000181475.1
Gm6297
predicted gene 6297
chr14_-_100149764 0.318 ENSMUST00000097079.4
Klf12
Kruppel-like factor 12
chr2_-_177267036 0.316 ENSMUST00000108963.1
Gm14409
predicted gene 14409
chr1_+_72284367 0.310 ENSMUST00000027380.5
ENSMUST00000141783.1
Tmem169

transmembrane protein 169

chr2_+_125136692 0.301 ENSMUST00000099452.2
Ctxn2
cortexin 2
chr10_+_75037291 0.293 ENSMUST00000139384.1
Rab36
RAB36, member RAS oncogene family
chr18_+_37655891 0.293 ENSMUST00000097608.2
3222401L13Rik
RIKEN cDNA 3222401L13 gene
chr14_-_75754475 0.284 ENSMUST00000049168.7
Cog3
component of oligomeric golgi complex 3
chr18_+_59062462 0.284 ENSMUST00000058633.2
ENSMUST00000175897.1
ENSMUST00000118510.1
ENSMUST00000175830.1
A730017C20Rik



RIKEN cDNA A730017C20 gene



chr4_-_129378116 0.276 ENSMUST00000030610.2
Zbtb8a
zinc finger and BTB domain containing 8a
chr7_-_80405425 0.269 ENSMUST00000107362.3
ENSMUST00000135306.1
Furin

furin (paired basic amino acid cleaving enzyme)

chr2_-_5895319 0.263 ENSMUST00000026926.4
ENSMUST00000102981.3
Sec61a2

Sec61, alpha subunit 2 (S. cerevisiae)

chr3_-_62506970 0.250 ENSMUST00000029336.4
Dhx36
DEAH (Asp-Glu-Ala-His) box polypeptide 36
chr7_+_57387304 0.231 ENSMUST00000085241.5
Gm9962
predicted gene 9962
chr11_+_78037959 0.220 ENSMUST00000073660.6
Flot2
flotillin 2
chr11_+_78037931 0.213 ENSMUST00000072289.5
ENSMUST00000100784.2
Flot2

flotillin 2

chr18_+_59062282 0.212 ENSMUST00000165666.2
A730017C20Rik
RIKEN cDNA A730017C20 gene
chr2_-_125782834 0.211 ENSMUST00000053699.6
Secisbp2l
SECIS binding protein 2-like
chr3_+_32436151 0.207 ENSMUST00000029201.7
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr10_+_116143881 0.207 ENSMUST00000105271.2
Ptprr
protein tyrosine phosphatase, receptor type, R
chr10_+_79996479 0.195 ENSMUST00000132517.1
Abca7
ATP-binding cassette, sub-family A (ABC1), member 7
chrX_+_169685191 0.193 ENSMUST00000112104.1
ENSMUST00000112107.1
Mid1

midline 1

chr2_+_69670100 0.190 ENSMUST00000100050.3
Klhl41
kelch-like 41
chr6_+_145934113 0.189 ENSMUST00000032383.7
Sspn
sarcospan
chr8_+_121116163 0.186 ENSMUST00000054691.6
Foxc2
forkhead box C2
chr3_+_94837533 0.176 ENSMUST00000107270.2
Pogz
pogo transposable element with ZNF domain
chr12_-_20900867 0.174 ENSMUST00000079237.5
Zfp125
zinc finger protein 125
chrY_+_90785442 0.173 ENSMUST00000177591.1
ENSMUST00000177671.1
ENSMUST00000179077.1
Erdr1


erythroid differentiation regulator 1


chr7_-_133702515 0.167 ENSMUST00000153698.1
Uros
uroporphyrinogen III synthase
chr9_+_100597686 0.165 ENSMUST00000124487.1
Stag1
stromal antigen 1
chr7_+_103550368 0.159 ENSMUST00000106888.1
Olfr613
olfactory receptor 613
chr7_-_57387172 0.157 ENSMUST00000068911.6
Gabrg3
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3
chr11_+_116843278 0.156 ENSMUST00000106370.3
Mettl23
methyltransferase like 23
chrX_+_16619698 0.154 ENSMUST00000026013.5
Maoa
monoamine oxidase A
chr18_+_23753708 0.150 ENSMUST00000115830.1
Mapre2
microtubule-associated protein, RP/EB family, member 2
chrX_-_157415286 0.148 ENSMUST00000079945.4
ENSMUST00000138396.1
Phex

phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)

chr18_+_24603952 0.145 ENSMUST00000025120.6
Elp2
elongator acetyltransferase complex subunit 2
chr11_+_102285161 0.144 ENSMUST00000156326.1
Tmub2
transmembrane and ubiquitin-like domain containing 2
chr4_+_146610961 0.140 ENSMUST00000130825.1
Gm13248
predicted gene 13248
chr19_-_57239310 0.140 ENSMUST00000111559.1
Ablim1
actin-binding LIM protein 1
chr7_+_39588931 0.140 ENSMUST00000178791.1
ENSMUST00000098511.3
Gm2058

predicted gene 2058

chr19_-_32196393 0.139 ENSMUST00000151822.1
Sgms1
sphingomyelin synthase 1
chr10_-_117148474 0.137 ENSMUST00000020381.3
Frs2
fibroblast growth factor receptor substrate 2
chr2_+_69897220 0.137 ENSMUST00000055758.9
ENSMUST00000112251.2
Ubr3

ubiquitin protein ligase E3 component n-recognin 3

chr12_+_102128718 0.125 ENSMUST00000159329.1
Slc24a4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr7_+_123123870 0.125 ENSMUST00000094053.5
Tnrc6a
trinucleotide repeat containing 6a
chr4_+_147132038 0.121 ENSMUST00000084149.3
Gm13139
predicted gene 13139
chr5_-_43981757 0.120 ENSMUST00000061299.7
Fgfbp1
fibroblast growth factor binding protein 1
chr11_+_51261719 0.119 ENSMUST00000130641.1
Clk4
CDC like kinase 4
chr10_+_116018213 0.118 ENSMUST00000063470.4
Ptprr
protein tyrosine phosphatase, receptor type, R
chr18_-_24603464 0.116 ENSMUST00000154205.1
Slc39a6
solute carrier family 39 (metal ion transporter), member 6
chr10_-_86011833 0.112 ENSMUST00000105304.1
ENSMUST00000061699.5
Bpifc

BPI fold containing family C

chr2_-_84650676 0.110 ENSMUST00000067232.3
Ctnnd1
catenin (cadherin associated protein), delta 1
chr17_+_22424248 0.110 ENSMUST00000120222.1
Zfp946
zinc finger protein 946
chr17_+_22424261 0.108 ENSMUST00000088763.6
Zfp946
zinc finger protein 946
chr9_+_110052016 0.108 ENSMUST00000164930.1
ENSMUST00000163979.1
Map4

microtubule-associated protein 4

chr2_+_23069210 0.105 ENSMUST00000155602.1
Acbd5
acyl-Coenzyme A binding domain containing 5
chr12_+_72536342 0.105 ENSMUST00000044352.6
Pcnxl4
pecanex-like 4 (Drosophila)
chr15_-_75905349 0.102 ENSMUST00000127550.1
Eef1d
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr18_+_55057557 0.099 ENSMUST00000181765.1
Gm4221
predicted gene 4221
chr19_+_5474681 0.098 ENSMUST00000165485.1
ENSMUST00000166253.1
ENSMUST00000167371.1
ENSMUST00000167855.1
ENSMUST00000070118.7
Efemp2




epidermal growth factor-containing fibulin-like extracellular matrix protein 2




chr10_+_23894688 0.097 ENSMUST00000041416.7
Vnn1
vanin 1
chr8_+_94172618 0.095 ENSMUST00000034214.6
Mt2
metallothionein 2
chr2_-_84650490 0.093 ENSMUST00000066177.3
Ctnnd1
catenin (cadherin associated protein), delta 1
chr6_+_37870786 0.092 ENSMUST00000120428.1
ENSMUST00000031859.7
Trim24

tripartite motif-containing 24

chr11_-_107337556 0.090 ENSMUST00000040380.6
Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chr2_-_84650714 0.088 ENSMUST00000111697.2
ENSMUST00000111670.2
ENSMUST00000111696.1
ENSMUST00000111678.1
ENSMUST00000111690.1
ENSMUST00000111695.1
ENSMUST00000111677.1
ENSMUST00000111698.1
ENSMUST00000099941.2
ENSMUST00000111676.1
ENSMUST00000111694.1
ENSMUST00000111675.1
ENSMUST00000111689.1
ENSMUST00000111687.1
ENSMUST00000111692.1
ENSMUST00000111685.1
ENSMUST00000111686.1
ENSMUST00000111688.1
ENSMUST00000111693.1
ENSMUST00000111684.1
Ctnnd1



















catenin (cadherin associated protein), delta 1



















chr7_-_100583072 0.087 ENSMUST00000152876.1
ENSMUST00000150042.1
Mrpl48

mitochondrial ribosomal protein L48

chr17_-_32886083 0.085 ENSMUST00000178401.1
Zfp870
zinc finger protein 870
chr8_+_107031218 0.080 ENSMUST00000034388.9
Vps4a
vacuolar protein sorting 4a (yeast)
chr4_-_149126688 0.077 ENSMUST00000030815.2
Cort
cortistatin
chr18_-_24603791 0.076 ENSMUST00000070726.3
Slc39a6
solute carrier family 39 (metal ion transporter), member 6
chr11_-_17008647 0.072 ENSMUST00000102881.3
Plek
pleckstrin
chr10_+_75037066 0.063 ENSMUST00000147802.1
ENSMUST00000020391.5
Rab36

RAB36, member RAS oncogene family

chr8_+_72219726 0.058 ENSMUST00000003123.8
Fam32a
family with sequence similarity 32, member A
chr14_+_4198185 0.056 ENSMUST00000180184.1
Gm2974
predicted gene 2974
chr4_+_147492417 0.055 ENSMUST00000105721.2
Gm13152
predicted gene 13152
chr2_-_84715160 0.045 ENSMUST00000035840.5
Zdhhc5
zinc finger, DHHC domain containing 5
chr1_+_194619815 0.038 ENSMUST00000027952.5
Plxna2
plexin A2
chr6_-_122340525 0.031 ENSMUST00000112600.2
Phc1
polyhomeotic-like 1 (Drosophila)
chr2_+_110597298 0.020 ENSMUST00000045972.6
ENSMUST00000111026.2
Slc5a12

solute carrier family 5 (sodium/glucose cotransporter), member 12

chr5_+_24393640 0.019 ENSMUST00000138168.1
ENSMUST00000115077.1
Abcb8

ATP-binding cassette, sub-family B (MDR/TAP), member 8

chr4_-_147809788 0.014 ENSMUST00000105734.3
ENSMUST00000176201.1
Gm13157
Gm20707
predicted gene 13157
predicted gene 20707
chr1_-_127840290 0.013 ENSMUST00000061512.2
Map3k19
mitogen-activated protein kinase kinase kinase 19
chr1_+_190928492 0.011 ENSMUST00000066632.7
ENSMUST00000110899.1
Angel2

angel homolog 2 (Drosophila)

chr1_-_168432270 0.004 ENSMUST00000072863.4
Pbx1
pre B cell leukemia homeobox 1
chrM_+_14138 0.004 ENSMUST00000082421.1
mt-Cytb
mitochondrially encoded cytochrome b
chr7_+_19119853 0.002 ENSMUST00000053109.3
Fbxo46
F-box protein 46
chr11_-_82908360 0.002 ENSMUST00000103213.3
Nle1
notchless homolog 1 (Drosophila)
chr5_-_34660068 0.001 ENSMUST00000041364.9
Nop14
NOP14 nucleolar protein
chr9_+_53771499 0.001 ENSMUST00000048670.8
Slc35f2
solute carrier family 35, member F2
chr2_+_32606979 0.000 ENSMUST00000113289.1
ENSMUST00000095044.3
St6galnac6

ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0015866 ADP transport(GO:0015866)
0.3 1.4 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.3 1.5 GO:0098735 cellular response to caffeine(GO:0071313) positive regulation of the force of heart contraction(GO:0098735)
0.2 1.0 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.2 1.0 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.2 0.5 GO:2000564 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.1 0.4 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.1 1.7 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.3 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.1 1.6 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.4 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.1 0.3 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 0.4 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.1 0.8 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.1 0.2 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 1.0 GO:0033572 transferrin transport(GO:0033572)
0.1 0.3 GO:0090472 dibasic protein processing(GO:0090472)
0.1 0.2 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.1 2.8 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 0.4 GO:1901525 negative regulation of macromitophagy(GO:1901525) regulation of mitophagy in response to mitochondrial depolarization(GO:1904923)
0.1 1.6 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.3 GO:0060690 epithelial cell differentiation involved in salivary gland development(GO:0060690)
0.1 0.3 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.1 0.6 GO:0032570 response to progesterone(GO:0032570)
0.1 0.3 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.1 0.4 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091) negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 0.2 GO:0042420 dopamine catabolic process(GO:0042420)
0.1 0.3 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.0 0.4 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 0.3 GO:0019532 oxalate transport(GO:0019532)
0.0 0.2 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780)
0.0 0.6 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.1 GO:0009838 abscission(GO:0009838)
0.0 0.2 GO:1902995 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995) positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.1 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.1 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.5 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.8 GO:0030903 notochord development(GO:0030903)
0.0 0.2 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012) negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.0 1.3 GO:0009063 cellular amino acid catabolic process(GO:0009063)
0.0 0.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.6 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.1 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.2 GO:0031272 regulation of pseudopodium assembly(GO:0031272)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0097637 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.2 2.8 GO:0042581 specific granule(GO:0042581)
0.1 0.4 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 0.6 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 0.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.4 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 1.2 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.5 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 1.6 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.3 GO:0005915 zonula adherens(GO:0005915)
0.0 0.3 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 1.5 GO:0014704 intercalated disc(GO:0014704)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.3 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.1 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.2 GO:0031143 pseudopodium(GO:0031143)
0.0 0.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.8 GO:0001669 acrosomal vesicle(GO:0001669)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.4 1.5 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.4 1.1 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.2 1.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.4 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.1 0.5 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.7 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.1 1.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 1.0 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 0.2 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.5 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 1.0 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 0.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0051378 primary amine oxidase activity(GO:0008131) serotonin binding(GO:0051378)
0.0 1.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.3 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 1.1 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.3 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.3 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.8 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.7 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0004984 olfactory receptor activity(GO:0004984)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.8 PID_ARF6_PATHWAY Arf6 signaling events
0.0 1.6 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.5 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.0 0.1 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.0 0.4 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 1.5 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.3 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 1.7 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.0 0.3 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 1.4 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 1.0 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.5 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.2 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters