Motif ID: Sox4

Z-value: 0.740


Transcription factors associated with Sox4:

Gene SymbolEntrez IDGene Name
Sox4 ENSMUSG00000076431.4 Sox4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox4mm10_v2_chr13_-_28953690_289537130.333.5e-02Click!


Activity profile for motif Sox4.

activity profile for motif Sox4


Sorted Z-values histogram for motif Sox4

Sorted Z-values for motif Sox4



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_+_3270767 3.830 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
Sepp1



selenoprotein P, plasma, 1



chr2_-_33942111 3.509 ENSMUST00000130988.1
ENSMUST00000127936.1
ENSMUST00000134271.1
Gm13403


predicted gene 13403


chr8_-_84773381 3.049 ENSMUST00000109764.1
Nfix
nuclear factor I/X
chr17_+_75005523 2.931 ENSMUST00000001927.5
Ltbp1
latent transforming growth factor beta binding protein 1
chr13_-_97747399 2.727 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr14_+_101840602 2.702 ENSMUST00000159314.1
Lmo7
LIM domain only 7
chr18_-_62756275 2.509 ENSMUST00000067450.1
ENSMUST00000048109.5
2700046A07Rik

RIKEN cDNA 2700046A07 gene

chr13_-_97747373 2.280 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr7_+_99466004 2.279 ENSMUST00000037359.2
Klhl35
kelch-like 35
chr14_+_101840501 2.073 ENSMUST00000159026.1
Lmo7
LIM domain only 7
chr1_+_165788681 1.877 ENSMUST00000161971.1
ENSMUST00000178336.1
ENSMUST00000005907.5
ENSMUST00000027849.4
Cd247



CD247 antigen



chr1_+_165788746 1.612 ENSMUST00000161559.2
Cd247
CD247 antigen
chr1_+_59482133 1.553 ENSMUST00000114246.2
ENSMUST00000037105.6
Fzd7

frizzled homolog 7 (Drosophila)

chr5_-_122050102 1.548 ENSMUST00000154139.1
Cux2
cut-like homeobox 2
chr10_-_17947997 1.413 ENSMUST00000037879.6
Heca
headcase homolog (Drosophila)
chrX_-_10117597 1.391 ENSMUST00000115543.2
ENSMUST00000044789.3
ENSMUST00000115544.2
Srpx


sushi-repeat-containing protein


chr12_-_98577940 1.209 ENSMUST00000110113.1
Kcnk10
potassium channel, subfamily K, member 10
chr12_-_79296266 1.202 ENSMUST00000021547.6
Zfyve26
zinc finger, FYVE domain containing 26
chr1_-_93101825 1.120 ENSMUST00000112958.2
Kif1a
kinesin family member 1A
chrX_+_159840463 1.102 ENSMUST00000112451.1
ENSMUST00000112453.2
Sh3kbp1

SH3-domain kinase binding protein 1

chr1_-_64122256 1.065 ENSMUST00000135075.1
Klf7
Kruppel-like factor 7 (ubiquitous)
chr3_+_135826075 1.054 ENSMUST00000029810.5
Slc39a8
solute carrier family 39 (metal ion transporter), member 8
chr1_+_158362330 1.038 ENSMUST00000170718.1
Astn1
astrotactin 1
chr7_-_105787544 1.009 ENSMUST00000078482.5
ENSMUST00000154659.1
Dchs1

dachsous 1 (Drosophila)

chr5_+_3928033 0.980 ENSMUST00000143365.1
Akap9
A kinase (PRKA) anchor protein (yotiao) 9
chr11_+_69364010 0.964 ENSMUST00000166700.1
Gm17305
predicted gene, 17305
chr18_+_37496997 0.958 ENSMUST00000059571.5
Pcdhb19
protocadherin beta 19
chr11_+_69846374 0.941 ENSMUST00000108632.1
Plscr3
phospholipid scramblase 3
chr17_-_79020816 0.893 ENSMUST00000168887.1
ENSMUST00000119284.1
Prkd3

protein kinase D3

chr2_-_180776900 0.885 ENSMUST00000108878.1
Bhlhe23
basic helix-loop-helix family, member e23
chr19_+_44931119 0.878 ENSMUST00000096053.3
Fam178a
family with sequence similarity 178, member A
chr4_-_91399984 0.864 ENSMUST00000102799.3
Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr1_-_93101854 0.860 ENSMUST00000171796.1
ENSMUST00000171556.1
Kif1a

kinesin family member 1A

chr11_+_69846665 0.837 ENSMUST00000019605.2
Plscr3
phospholipid scramblase 3
chr11_+_69846610 0.812 ENSMUST00000152566.1
ENSMUST00000108633.2
Plscr3

phospholipid scramblase 3

chr18_+_37300799 0.808 ENSMUST00000051754.1
Pcdhb3
protocadherin beta 3
chr10_+_13966268 0.797 ENSMUST00000015645.4
Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr4_+_41762309 0.772 ENSMUST00000108042.2
Il11ra1
interleukin 11 receptor, alpha chain 1
chr3_-_75956888 0.739 ENSMUST00000038563.7
ENSMUST00000167078.1
ENSMUST00000117242.1
Golim4


golgi integral membrane protein 4


chr6_-_39557830 0.726 ENSMUST00000036877.3
ENSMUST00000154149.1
Dennd2a

DENN/MADD domain containing 2A

chr1_+_158362261 0.717 ENSMUST00000046110.9
Astn1
astrotactin 1
chr11_+_22512088 0.707 ENSMUST00000059319.7
Tmem17
transmembrane protein 17
chr12_+_29528382 0.675 ENSMUST00000049784.9
Myt1l
myelin transcription factor 1-like
chr6_-_38875965 0.653 ENSMUST00000160360.1
Hipk2
homeodomain interacting protein kinase 2
chr8_+_88697022 0.652 ENSMUST00000043526.8
Cyld
cylindromatosis (turban tumor syndrome)
chr12_+_19606929 0.626 ENSMUST00000105167.1
Gm9257
predicted gene 9257
chr6_+_4903298 0.610 ENSMUST00000035813.2
Ppp1r9a
protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr14_+_54936456 0.606 ENSMUST00000037814.6
Cmtm5
CKLF-like MARVEL transmembrane domain containing 5
chr18_+_37484955 0.598 ENSMUST00000053856.4
Pcdhb17
protocadherin beta 17
chr4_+_136286061 0.596 ENSMUST00000069195.4
ENSMUST00000130658.1
Zfp46

zinc finger protein 46

chr5_-_31291026 0.574 ENSMUST00000041565.7
Ift172
intraflagellar transport 172
chr7_-_105787567 0.570 ENSMUST00000144189.1
Dchs1
dachsous 1 (Drosophila)
chr11_-_100650693 0.547 ENSMUST00000103119.3
Zfp385c
zinc finger protein 385C
chr1_+_181150926 0.542 ENSMUST00000134115.1
ENSMUST00000111059.1
Cnih4

cornichon homolog 4 (Drosophila)

chr18_+_37421418 0.526 ENSMUST00000053073.4
Pcdhb11
protocadherin beta 11
chr10_-_116473875 0.518 ENSMUST00000068233.4
Kcnmb4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr9_-_32541589 0.509 ENSMUST00000016231.7
Fli1
Friend leukemia integration 1
chr14_+_64589802 0.501 ENSMUST00000180610.1
A930011O12Rik
RIKEN cDNA A930011O12 gene
chr18_-_43059418 0.489 ENSMUST00000025377.7
Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr5_-_106696819 0.482 ENSMUST00000127434.1
ENSMUST00000112696.1
ENSMUST00000112698.1
Zfp644


zinc finger protein 644


chr5_-_106696530 0.462 ENSMUST00000137285.1
ENSMUST00000124263.1
ENSMUST00000112695.1
ENSMUST00000155495.1
ENSMUST00000135108.1
Zfp644




zinc finger protein 644




chr12_+_49385174 0.454 ENSMUST00000110746.1
3110039M20Rik
RIKEN cDNA 3110039M20 gene
chr2_-_121806988 0.443 ENSMUST00000110592.1
Frmd5
FERM domain containing 5
chr17_-_35704000 0.442 ENSMUST00000097333.3
ENSMUST00000003628.6
Ddr1

discoidin domain receptor family, member 1

chr12_-_24252181 0.442 ENSMUST00000169148.1
Gm9312
predicted gene 9312
chr2_-_165898951 0.419 ENSMUST00000136842.1
Zmynd8
zinc finger, MYND-type containing 8
chr18_+_37489465 0.415 ENSMUST00000055949.2
Pcdhb18
protocadherin beta 18
chr13_+_9276477 0.398 ENSMUST00000174552.1
Dip2c
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr10_-_116473418 0.398 ENSMUST00000087965.4
ENSMUST00000164271.1
Kcnmb4

potassium large conductance calcium-activated channel, subfamily M, beta member 4

chr2_-_180776749 0.394 ENSMUST00000061098.2
Bhlhe23
basic helix-loop-helix family, member e23
chr12_+_24831583 0.387 ENSMUST00000110942.3
ENSMUST00000078902.6
Mboat2

membrane bound O-acyltransferase domain containing 2

chr12_+_21111778 0.362 ENSMUST00000050990.9
Asap2
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr17_-_35704574 0.358 ENSMUST00000117301.1
ENSMUST00000134995.1
Ddr1

discoidin domain receptor family, member 1

chr2_-_168206875 0.357 ENSMUST00000057793.4
Adnp
activity-dependent neuroprotective protein
chr5_-_131538687 0.348 ENSMUST00000161374.1
Auts2
autism susceptibility candidate 2
chr17_-_68004075 0.347 ENSMUST00000024840.5
Arhgap28
Rho GTPase activating protein 28
chr9_+_13765970 0.346 ENSMUST00000152532.1
Mtmr2
myotubularin related protein 2
chr17_-_35697971 0.340 ENSMUST00000146472.1
Ddr1
discoidin domain receptor family, member 1
chr16_-_91044473 0.331 ENSMUST00000118522.1
Paxbp1
PAX3 and PAX7 binding protein 1
chr11_+_54314960 0.311 ENSMUST00000064690.3
ENSMUST00000108899.1
Acsl6

acyl-CoA synthetase long-chain family member 6

chr5_-_134456702 0.308 ENSMUST00000073161.5
ENSMUST00000171794.2
ENSMUST00000111245.2
ENSMUST00000100654.3
ENSMUST00000167084.2
ENSMUST00000100652.3
ENSMUST00000100650.3
ENSMUST00000074114.5
Gtf2ird1







general transcription factor II I repeat domain-containing 1







chr9_-_103480328 0.306 ENSMUST00000124310.2
Bfsp2
beaded filament structural protein 2, phakinin
chr9_+_104002546 0.290 ENSMUST00000035167.8
ENSMUST00000117054.1
Nphp3

nephronophthisis 3 (adolescent)

chr1_-_36557517 0.287 ENSMUST00000114990.1
ENSMUST00000128104.1
ENSMUST00000027295.4
Sema4c


sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C


chr5_+_19907502 0.280 ENSMUST00000101558.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr2_-_26910569 0.251 ENSMUST00000015920.5
ENSMUST00000139815.1
ENSMUST00000102899.3
Med22


mediator complex subunit 22


chr17_+_68837062 0.237 ENSMUST00000178545.1
Tmem200c
transmembrane protein 200C
chr16_+_84834901 0.236 ENSMUST00000114184.1
Gabpa
GA repeat binding protein, alpha
chr5_+_3928267 0.235 ENSMUST00000044492.8
Akap9
A kinase (PRKA) anchor protein (yotiao) 9
chr7_-_100514800 0.234 ENSMUST00000054923.7
Dnajb13
DnaJ (Hsp40) related, subfamily B, member 13
chr12_+_8674129 0.220 ENSMUST00000111123.2
ENSMUST00000178015.1
ENSMUST00000020915.3
Pum2


pumilio 2 (Drosophila)


chr13_+_117220584 0.212 ENSMUST00000022242.7
Emb
embigin
chr8_-_11635745 0.200 ENSMUST00000033905.5
ENSMUST00000169782.1
Ankrd10

ankyrin repeat domain 10

chr5_-_138155694 0.187 ENSMUST00000132318.1
ENSMUST00000049393.8
Zfp113

zinc finger protein 113

chr16_+_17070127 0.186 ENSMUST00000115729.1
Ypel1
yippee-like 1 (Drosophila)
chr13_+_51100810 0.172 ENSMUST00000095797.5
Spin1
spindlin 1
chr5_+_44100442 0.159 ENSMUST00000072800.4
Gm16401
predicted gene 16401
chr1_-_55027473 0.157 ENSMUST00000027127.7
Sf3b1
splicing factor 3b, subunit 1
chr5_+_25246775 0.156 ENSMUST00000144971.1
Galnt11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11
chr1_+_135729147 0.132 ENSMUST00000027677.7
Csrp1
cysteine and glycine-rich protein 1
chr7_+_100493795 0.132 ENSMUST00000129324.1
Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr12_-_72236692 0.128 ENSMUST00000021497.9
ENSMUST00000137990.1
Rtn1

reticulon 1

chr17_-_27622785 0.125 ENSMUST00000176458.1
ENSMUST00000114886.1
Nudt3

nudix (nucleotide diphosphate linked moiety X)-type motif 3

chr12_-_72408934 0.124 ENSMUST00000078505.7
Rtn1
reticulon 1
chr11_-_78497458 0.121 ENSMUST00000108287.3
Sarm1
sterile alpha and HEAT/Armadillo motif containing 1
chr2_-_125782834 0.110 ENSMUST00000053699.6
Secisbp2l
SECIS binding protein 2-like
chr1_+_135146782 0.109 ENSMUST00000027684.4
Arl8a
ADP-ribosylation factor-like 8A
chr4_+_129513581 0.100 ENSMUST00000062356.6
Marcksl1
MARCKS-like 1
chrX_-_145505175 0.099 ENSMUST00000143610.1
Amot
angiomotin
chr11_-_85139939 0.095 ENSMUST00000108075.2
Usp32
ubiquitin specific peptidase 32
chr7_+_100494044 0.085 ENSMUST00000153287.1
Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr2_+_78869009 0.075 ENSMUST00000028398.7
Ube2e3
ubiquitin-conjugating enzyme E2E 3
chr11_-_49187159 0.073 ENSMUST00000046522.6
Btnl9
butyrophilin-like 9
chr18_-_15063560 0.068 ENSMUST00000168989.1
Kctd1
potassium channel tetramerisation domain containing 1
chr12_-_112673944 0.066 ENSMUST00000130342.1
Akt1
thymoma viral proto-oncogene 1
chr15_-_76656905 0.045 ENSMUST00000176274.1
Cyhr1
cysteine and histidine rich 1
chr5_-_24445254 0.040 ENSMUST00000030800.6
Fastk
Fas-activated serine/threonine kinase
chr15_+_44428073 0.038 ENSMUST00000060652.3
Eny2
enhancer of yellow 2 homolog (Drosophila)
chr3_-_95133989 0.036 ENSMUST00000172572.2
ENSMUST00000173462.2
Scnm1

sodium channel modifier 1

chr11_-_78497734 0.012 ENSMUST00000061174.6
Sarm1
sterile alpha and HEAT/Armadillo motif containing 1
chr11_+_70432627 0.010 ENSMUST00000084954.6
ENSMUST00000108568.3
ENSMUST00000079056.2
ENSMUST00000102564.4
ENSMUST00000124943.1
ENSMUST00000150076.1
ENSMUST00000102563.1
Arrb2






arrestin, beta 2







Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.4 1.3 GO:0046671 negative regulation of retinal cell programmed cell death(GO:0046671)
0.4 1.6 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.4 1.6 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.2 1.8 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.2 0.6 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.2 3.0 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.7 GO:0097343 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.1 0.9 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 1.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 3.5 GO:0070207 protein homotrimerization(GO:0070207)
0.1 0.3 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.1 0.9 GO:0005513 detection of calcium ion(GO:0005513)
0.1 2.9 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.1 1.1 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1 2.0 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 0.3 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 1.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.3 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.4 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 1.9 GO:0007614 short-term memory(GO:0007614)
0.1 1.2 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.1 0.7 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 0.3 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.1 0.3 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.8 GO:0046697 decidualization(GO:0046697)
0.0 0.1 GO:0071544 diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.0 0.5 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.2 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.0 2.6 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.3 GO:0031642 negative regulation of myelination(GO:0031642) negative regulation of excitatory postsynaptic potential(GO:0090394) negative regulation of receptor catabolic process(GO:2000645)
0.0 0.6 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.3 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.0 0.2 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.2 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 0.3 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.2 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0 0.1 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.1 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.1 GO:1903351 response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
0.0 2.1 GO:0007416 synapse assembly(GO:0007416)
0.0 0.3 GO:0035855 megakaryocyte development(GO:0035855)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.9 3.5 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.3 1.2 GO:0044307 dendritic branch(GO:0044307)
0.1 0.6 GO:1990761 growth cone lamellipodium(GO:1990761)
0.1 0.3 GO:0097543 ciliary inversin compartment(GO:0097543)
0.1 0.7 GO:0097542 ciliary tip(GO:0097542)
0.0 1.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 4.8 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 2.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.6 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.4 GO:0005776 autophagosome(GO:0005776)
0.0 0.1 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.7 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.8 GO:0005871 kinesin complex(GO:0005871)
0.0 1.3 GO:0030496 midbody(GO:0030496)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.9 GO:0050436 microfibril binding(GO:0050436)
0.2 0.8 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.2 2.6 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 4.8 GO:0042805 actinin binding(GO:0042805)
0.1 1.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 1.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.7 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.7 GO:0046790 virion binding(GO:0046790)
0.1 1.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.4 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 0.5 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 0.9 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 0.7 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 1.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.2 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 3.5 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.0 1.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.9 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.2 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.2 GO:0102391 decanoate--CoA ligase activity(GO:0102391)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.5 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.1 1.6 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 3.9 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.7 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.0 1.1 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 0.6 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.5 PID_ATR_PATHWAY ATR signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.5 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2 1.2 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 1.1 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 1.2 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.9 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 1.1 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.4 REACTOME_ACYL_CHAIN_REMODELLING_OF_PC Genes involved in Acyl chain remodelling of PC
0.0 0.3 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.7 REACTOME_NOD1_2_SIGNALING_PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.3 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions