Motif ID: Irx6_Irx2_Irx3

Z-value: 0.825

Transcription factors associated with Irx6_Irx2_Irx3:

Gene SymbolEntrez IDGene Name
Irx2 ENSMUSG00000001504.9 Irx2
Irx3 ENSMUSG00000031734.11 Irx3
Irx6 ENSMUSG00000031738.8 Irx6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Irx2mm10_v2_chr13_+_72628831_72628971-0.163.1e-01Click!
Irx3mm10_v2_chr8_-_91801948_918020670.124.7e-01Click!
Irx6mm10_v2_chr8_+_92674826_926748260.047.8e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Irx6_Irx2_Irx3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_45311538 7.844 ENSMUST00000087883.6
Col3a1
collagen, type III, alpha 1
chr17_+_17316078 2.782 ENSMUST00000105311.3
Gm6712
predicted gene 6712
chr9_-_124493793 2.570 ENSMUST00000178787.1
Gm21836
predicted gene, 21836
chr8_+_84872105 2.496 ENSMUST00000136026.1
ENSMUST00000170296.1
Syce2

synaptonemal complex central element protein 2

chr12_-_74316394 2.476 ENSMUST00000110441.1
Gm11042
predicted gene 11042
chr10_+_61171954 2.289 ENSMUST00000122261.1
ENSMUST00000121297.1
ENSMUST00000035894.5
Tbata


thymus, brain and testes associated


chr18_+_36664060 1.945 ENSMUST00000036765.7
Eif4ebp3
eukaryotic translation initiation factor 4E binding protein 3
chr18_+_35770318 1.853 ENSMUST00000165299.1
Gm16490
predicted gene 16490
chr13_+_49504774 1.772 ENSMUST00000051504.7
Ecm2
extracellular matrix protein 2, female organ and adipocyte specific
chr7_+_140763739 1.675 ENSMUST00000026552.7
Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
chr10_-_29699379 1.658 ENSMUST00000092620.4
Gm10275
predicted pseudogene 10275
chr10_-_39122277 1.595 ENSMUST00000136546.1
Fam229b
family with sequence similarity 229, member B
chr12_+_69963452 1.569 ENSMUST00000110560.1
Gm3086
predicted gene 3086
chr6_-_48708206 1.545 ENSMUST00000119315.1
ENSMUST00000053661.4
Gimap6

GTPase, IMAP family member 6

chr2_-_98667264 1.502 ENSMUST00000099683.1
Gm10800
predicted gene 10800
chr13_+_23544052 1.408 ENSMUST00000075558.2
Hist1h3f
histone cluster 1, H3f
chr2_-_67433181 1.362 ENSMUST00000180773.1
Gm26727
predicted gene, 26727
chr3_+_106034661 1.313 ENSMUST00000170669.2
Gm4540
predicted gene 4540
chr17_-_25785533 1.292 ENSMUST00000140738.1
ENSMUST00000145053.1
ENSMUST00000138759.1
ENSMUST00000133071.1
ENSMUST00000077938.3
Haghl




hydroxyacylglutathione hydrolase-like




chr14_-_31001311 1.286 ENSMUST00000161219.1
ENSMUST00000182501.1
Spcs1

signal peptidase complex subunit 1 homolog (S. cerevisiae)

chr15_-_35938186 1.255 ENSMUST00000014457.8
Cox6c
cytochrome c oxidase subunit VIc
chr4_-_139131058 1.169 ENSMUST00000143971.1
Minos1
mitochondrial inner membrane organizing system 1
chr2_+_124089961 1.088 ENSMUST00000103241.1
Sema6d
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr17_-_25785324 1.084 ENSMUST00000150324.1
Haghl
hydroxyacylglutathione hydrolase-like
chr14_+_31001383 1.065 ENSMUST00000168584.1
Glt8d1
glycosyltransferase 8 domain containing 1
chr15_-_35938009 1.063 ENSMUST00000156915.1
Cox6c
cytochrome c oxidase subunit VIc
chr14_+_31001414 1.045 ENSMUST00000022476.7
Glt8d1
glycosyltransferase 8 domain containing 1
chr3_-_57651667 1.006 ENSMUST00000160959.1
Commd2
COMM domain containing 2
chr6_+_80019008 0.939 ENSMUST00000126399.1
ENSMUST00000136421.1
Lrrtm4

leucine rich repeat transmembrane neuronal 4

chrM_+_7759 0.926 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chrX_+_106920618 0.926 ENSMUST00000060576.7
Lpar4
lysophosphatidic acid receptor 4
chr9_+_64173364 0.904 ENSMUST00000034966.7
Rpl4
ribosomal protein L4
chr1_+_60181495 0.897 ENSMUST00000160834.1
Nbeal1
neurobeachin like 1
chr6_-_56901870 0.894 ENSMUST00000101367.2
Nt5c3
5'-nucleotidase, cytosolic III
chr11_-_26591729 0.892 ENSMUST00000109504.1
Vrk2
vaccinia related kinase 2
chr6_+_79818031 0.882 ENSMUST00000179797.1
Gm20594
predicted gene, 20594
chr14_+_13454010 0.881 ENSMUST00000112656.2
Synpr
synaptoporin
chr13_+_73330982 0.876 ENSMUST00000022098.8
Mrpl36
mitochondrial ribosomal protein L36
chr1_+_194938821 0.865 ENSMUST00000016638.2
ENSMUST00000110815.2
Cd34

CD34 antigen

chr16_-_16560201 0.817 ENSMUST00000162045.1
ENSMUST00000162124.1
ENSMUST00000161861.1
Fgd4


FYVE, RhoGEF and PH domain containing 4


chr6_-_3494587 0.811 ENSMUST00000049985.8
Hepacam2
HEPACAM family member 2
chr17_-_57839233 0.802 ENSMUST00000095218.3
Rpl7a-ps5
ribosomal protein L7A, pseudogene 5
chr7_-_103827922 0.800 ENSMUST00000023934.6
ENSMUST00000153218.1
Hbb-bs

hemoglobin, beta adult s chain

chr11_+_100320596 0.795 ENSMUST00000152521.1
Eif1
eukaryotic translation initiation factor 1
chr19_-_6908289 0.791 ENSMUST00000149261.1
Prdx5
peroxiredoxin 5
chr11_-_76399107 0.778 ENSMUST00000021204.3
Nxn
nucleoredoxin
chr4_-_108118528 0.778 ENSMUST00000030340.8
Scp2
sterol carrier protein 2, liver
chr12_+_55124528 0.776 ENSMUST00000177768.1
Fam177a
family with sequence similarity 177, member A
chr2_-_119271202 0.768 ENSMUST00000037360.7
Rhov
ras homolog gene family, member V
chr7_+_28350652 0.767 ENSMUST00000082134.4
Rps16
ribosomal protein S16
chr1_+_140246216 0.763 ENSMUST00000119786.1
ENSMUST00000120796.1
ENSMUST00000060201.8
ENSMUST00000120709.1
Kcnt2



potassium channel, subfamily T, member 2



chr8_+_129118043 0.758 ENSMUST00000108744.1
1700008F21Rik
RIKEN cDNA 1700008F21 gene
chr2_+_133552159 0.745 ENSMUST00000028836.6
Bmp2
bone morphogenetic protein 2
chr7_-_60005101 0.740 ENSMUST00000059305.10
Snrpn
small nuclear ribonucleoprotein N
chr13_-_27582168 0.720 ENSMUST00000006664.1
ENSMUST00000095926.1
Prl8a1

prolactin family 8, subfamily a, member 1

chrM_+_8600 0.718 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chr15_+_99006056 0.715 ENSMUST00000079818.3
Gm8973
predicted gene 8973
chr17_+_46496753 0.713 ENSMUST00000046497.6
Dnph1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr10_+_26229707 0.712 ENSMUST00000060716.5
ENSMUST00000164660.1
Samd3

sterile alpha motif domain containing 3

chr17_-_27133902 0.664 ENSMUST00000119227.1
ENSMUST00000025045.8
Uqcc2

ubiquinol-cytochrome c reductase complex assembly factor 2

chr17_-_21933022 0.659 ENSMUST00000074295.7
Zfp942
zinc finger protein 942
chr13_+_76579670 0.655 ENSMUST00000126960.1
ENSMUST00000109583.2
Mctp1

multiple C2 domains, transmembrane 1

chr19_-_12765447 0.651 ENSMUST00000112933.1
Cntf
ciliary neurotrophic factor
chr12_-_84617326 0.640 ENSMUST00000021666.4
Abcd4
ATP-binding cassette, sub-family D (ALD), member 4
chr11_+_43474276 0.637 ENSMUST00000173002.1
ENSMUST00000057679.3
C1qtnf2

C1q and tumor necrosis factor related protein 2

chr1_-_173942445 0.627 ENSMUST00000042228.8
ENSMUST00000081216.5
ENSMUST00000129829.1
ENSMUST00000123708.1
ENSMUST00000111210.2
Ifi203



Mndal
interferon activated gene 203



myeloid nuclear differentiation antigen like
chr12_-_81379464 0.609 ENSMUST00000062182.7
Gm4787
predicted gene 4787
chr3_+_51559757 0.602 ENSMUST00000180616.1
5031434O11Rik
RIKEN cDNA 5031434O11 gene
chr8_-_106573461 0.601 ENSMUST00000073722.5
Gm10073
predicted pseudogene 10073
chr7_-_130547358 0.599 ENSMUST00000160289.1
Nsmce4a
non-SMC element 4 homolog A (S. cerevisiae)
chr3_-_150073620 0.591 ENSMUST00000057740.5
Rpsa-ps10
ribosomal protein SA, pseudogene 10
chr16_-_77602094 0.591 ENSMUST00000114231.1
Gm11146
predicted gene 11146
chr19_-_32466575 0.591 ENSMUST00000078034.3
Rpl9-ps6
ribosomal protein L9, pseudogene 6
chr18_-_20682963 0.584 ENSMUST00000165229.2
Gm10269
predicted gene 10269
chr5_-_129623655 0.573 ENSMUST00000076842.5
Gm6139
predicted gene 6139
chr9_+_115909455 0.571 ENSMUST00000119291.1
ENSMUST00000069651.6
Gadl1

glutamate decarboxylase-like 1

chrX_-_139714481 0.561 ENSMUST00000183728.1
Gm15013
predicted gene 15013
chr13_+_100669481 0.548 ENSMUST00000057325.7
ENSMUST00000170347.2
Ccdc125

coiled-coil domain containing 125

chr6_-_88875035 0.535 ENSMUST00000145944.1
Podxl2
podocalyxin-like 2
chr15_-_81843699 0.533 ENSMUST00000092020.2
Gm8444
predicted gene 8444
chr5_-_5664196 0.527 ENSMUST00000061008.3
ENSMUST00000054865.6
A330021E22Rik

RIKEN cDNA A330021E22 gene

chr6_-_136941887 0.509 ENSMUST00000111891.1
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr14_+_57798182 0.507 ENSMUST00000111269.1
Sap18
Sin3-associated polypeptide 18
chr5_-_134614953 0.506 ENSMUST00000036362.6
ENSMUST00000077636.4
Lat2

linker for activation of T cells family, member 2

chr10_+_82378593 0.500 ENSMUST00000165906.1
Gm4924
predicted gene 4924
chr4_+_53826014 0.497 ENSMUST00000030127.6
Tmem38b
transmembrane protein 38B
chr7_+_19212521 0.491 ENSMUST00000060225.4
Gpr4
G protein-coupled receptor 4
chr9_-_35570393 0.488 ENSMUST00000115110.4
Hyls1
hydrolethalus syndrome 1
chr16_+_17146937 0.482 ENSMUST00000115706.1
ENSMUST00000069064.4
Ydjc

YdjC homolog (bacterial)

chr6_-_106800051 0.482 ENSMUST00000013882.7
ENSMUST00000049675.4
ENSMUST00000113239.3
Crbn


cereblon


chr6_+_142414012 0.480 ENSMUST00000141548.1
B230216G23Rik
RIKEN cDNA B230216G23 gene
chr2_-_169405435 0.479 ENSMUST00000131509.1
4930529I22Rik
RIKEN cDNA 4930529I22 gene
chr5_-_100674230 0.478 ENSMUST00000031262.7
Coq2
coenzyme Q2 homolog, prenyltransferase (yeast)
chr4_+_154142363 0.470 ENSMUST00000030895.5
Wrap73
WD repeat containing, antisense to Trp73
chrM_+_3906 0.463 ENSMUST00000082396.1
mt-Nd2
mitochondrially encoded NADH dehydrogenase 2
chr6_+_86371489 0.450 ENSMUST00000089558.5
Snrpg
small nuclear ribonucleoprotein polypeptide G
chr2_+_177768044 0.445 ENSMUST00000108942.3
Gm14322
predicted gene 14322
chr5_-_13121766 0.442 ENSMUST00000078246.4
Gm10108
predicted pseudogene 10108
chr7_+_127573376 0.440 ENSMUST00000033086.1
Phkg2
phosphorylase kinase, gamma 2 (testis)
chr1_-_195092242 0.440 ENSMUST00000162650.1
ENSMUST00000160817.1
ENSMUST00000162614.1
ENSMUST00000016637.6
Cd46



CD46 antigen, complement regulatory protein



chr10_+_39732099 0.434 ENSMUST00000019986.6
Rev3l
REV3-like, catalytic subunit of DNA polymerase zeta RAD54 like (S. cerevisiae)
chr12_+_17924294 0.425 ENSMUST00000169657.1
B430203G13Rik
RIKEN cDNA B430203G13 gene
chr7_-_101845300 0.418 ENSMUST00000094141.5
Folr2
folate receptor 2 (fetal)
chr16_-_36784924 0.414 ENSMUST00000168279.1
ENSMUST00000164579.1
ENSMUST00000023616.2
Slc15a2


solute carrier family 15 (H+/peptide transporter), member 2


chr3_+_105973711 0.412 ENSMUST00000000573.2
Ovgp1
oviductal glycoprotein 1
chr6_-_136941694 0.411 ENSMUST00000032344.5
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr3_-_113577743 0.408 ENSMUST00000067980.5
Amy1
amylase 1, salivary
chr18_-_67724560 0.407 ENSMUST00000120934.1
ENSMUST00000025420.7
ENSMUST00000122412.1
Ptpn2


protein tyrosine phosphatase, non-receptor type 2


chr6_+_41546730 0.401 ENSMUST00000103299.1
Trbc2
T cell receptor beta, constant 2
chrX_-_164980279 0.399 ENSMUST00000112247.2
Mospd2
motile sperm domain containing 2
chr5_-_43981757 0.398 ENSMUST00000061299.7
Fgfbp1
fibroblast growth factor binding protein 1
chr2_-_86347764 0.396 ENSMUST00000099894.2
Olfr1055
olfactory receptor 1055
chr8_+_34154563 0.392 ENSMUST00000033933.5
Tmem66
transmembrane protein 66
chr8_+_56551090 0.391 ENSMUST00000040218.5
ENSMUST00000110322.3
Fbxo8

F-box protein 8

chr6_-_28397999 0.391 ENSMUST00000035930.4
Zfp800
zinc finger protein 800
chr14_+_123659971 0.388 ENSMUST00000049681.7
Itgbl1
integrin, beta-like 1
chr11_-_68927049 0.386 ENSMUST00000038932.7
Odf4
outer dense fiber of sperm tails 4
chr8_+_53511695 0.386 ENSMUST00000033920.4
Aga
aspartylglucosaminidase
chr4_-_116075022 0.381 ENSMUST00000050580.4
ENSMUST00000078676.5
Uqcrh

ubiquinol-cytochrome c reductase hinge protein

chr10_-_81266906 0.380 ENSMUST00000046114.4
Mrpl54
mitochondrial ribosomal protein L54
chrX_+_56454871 0.376 ENSMUST00000039374.2
ENSMUST00000101553.2
Ddx26b

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

chr9_-_56161051 0.370 ENSMUST00000034876.8
Tspan3
tetraspanin 3
chr7_-_79386943 0.365 ENSMUST00000053718.8
ENSMUST00000179243.1
Rlbp1

retinaldehyde binding protein 1

chr9_-_54950954 0.362 ENSMUST00000054018.5
AY074887
cDNA sequence AY074887
chr3_+_121291725 0.360 ENSMUST00000039442.7
Alg14
asparagine-linked glycosylation 14
chr7_-_46672537 0.356 ENSMUST00000049298.7
Tph1
tryptophan hydroxylase 1
chr13_-_104863883 0.346 ENSMUST00000043061.4
Fam159b
family with sequence similarity 159, member B
chr1_+_138963709 0.345 ENSMUST00000168527.1
Dennd1b
DENN/MADD domain containing 1B
chr1_+_171840607 0.345 ENSMUST00000136479.1
ENSMUST00000042302.6
Cd84

CD84 antigen

chr10_-_30655859 0.341 ENSMUST00000092610.4
Ncoa7
nuclear receptor coactivator 7
chr9_+_110656494 0.339 ENSMUST00000019803.4
Ccdc12
coiled-coil domain containing 12
chr10_-_80900749 0.339 ENSMUST00000020440.6
Timm13
translocase of inner mitochondrial membrane 13
chr18_-_62756275 0.338 ENSMUST00000067450.1
ENSMUST00000048109.5
2700046A07Rik

RIKEN cDNA 2700046A07 gene

chr12_-_81421910 0.334 ENSMUST00000085319.3
Adam4
a disintegrin and metallopeptidase domain 4
chr14_+_44102654 0.332 ENSMUST00000074839.6
Ear2
eosinophil-associated, ribonuclease A family, member 2
chr5_-_17849783 0.332 ENSMUST00000170051.1
ENSMUST00000165232.1
Cd36

CD36 antigen

chr6_+_138140521 0.331 ENSMUST00000120939.1
ENSMUST00000120302.1
Mgst1

microsomal glutathione S-transferase 1

chrX_-_150440887 0.328 ENSMUST00000163233.1
Tmem29
transmembrane protein 29
chr10_-_100589205 0.324 ENSMUST00000054471.8
4930430F08Rik
RIKEN cDNA 4930430F08 gene
chr14_+_53324632 0.319 ENSMUST00000178100.1
Trav7n-6
T cell receptor alpha variable 7N-6
chr13_+_90923122 0.314 ENSMUST00000051955.7
Rps23
ribosomal protein S23
chr2_+_11778480 0.313 ENSMUST00000056108.5
Ankrd16
ankyrin repeat domain 16
chr2_+_84826997 0.313 ENSMUST00000028470.3
Timm10
translocase of inner mitochondrial membrane 10
chr11_+_98026695 0.312 ENSMUST00000092425.4
Rpl19
ribosomal protein L19
chr9_-_22071345 0.309 ENSMUST00000179605.1
ENSMUST00000043922.6
Zfp653

zinc finger protein 653

chr16_-_18089022 0.308 ENSMUST00000132241.1
ENSMUST00000139861.1
ENSMUST00000003620.5
Prodh


proline dehydrogenase


chr17_+_40811089 0.307 ENSMUST00000024721.7
Rhag
Rhesus blood group-associated A glycoprotein
chr11_+_98026918 0.303 ENSMUST00000017548.6
Rpl19
ribosomal protein L19
chr17_-_47688028 0.301 ENSMUST00000113301.1
ENSMUST00000113302.3
Tomm6

translocase of outer mitochondrial membrane 6 homolog (yeast)

chr4_-_36136463 0.301 ENSMUST00000098151.2
Lingo2
leucine rich repeat and Ig domain containing 2
chr8_+_84908560 0.298 ENSMUST00000003910.6
ENSMUST00000109744.1
Dnase2a

deoxyribonuclease II alpha

chr3_+_106113229 0.298 ENSMUST00000079132.5
ENSMUST00000139086.1
Chia

chitinase, acidic

chr4_+_21727695 0.298 ENSMUST00000065928.4
Ccnc
cyclin C
chr9_+_21411824 0.297 ENSMUST00000002902.6
Qtrt1
queuine tRNA-ribosyltransferase 1
chr4_+_129336012 0.292 ENSMUST00000119480.1
Zbtb8os
zinc finger and BTB domain containing 8 opposite strand
chr3_-_123672321 0.291 ENSMUST00000172537.1
ENSMUST00000029602.6
Ndst3

N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3

chr6_+_133105239 0.291 ENSMUST00000100864.4
2700089E24Rik
RIKEN cDNA 2700089E24 gene
chr14_-_55944536 0.289 ENSMUST00000022834.6
Cma1
chymase 1, mast cell
chr15_+_85116829 0.289 ENSMUST00000105085.1
Gm10923
predicted gene 10923
chr4_+_129335593 0.287 ENSMUST00000141235.1
Zbtb8os
zinc finger and BTB domain containing 8 opposite strand
chr4_-_96553617 0.286 ENSMUST00000030303.5
Cyp2j6
cytochrome P450, family 2, subfamily j, polypeptide 6
chr7_-_80324115 0.278 ENSMUST00000123189.1
Rccd1
RCC1 domain containing 1
chr15_-_3979432 0.278 ENSMUST00000022791.8
Fbxo4
F-box protein 4
chr8_+_4625840 0.276 ENSMUST00000073201.5
Zfp958
zinc finger protein 958
chr10_-_91123955 0.276 ENSMUST00000164505.1
ENSMUST00000170810.1
ENSMUST00000076694.6
Slc25a3


solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3


chr10_+_59702477 0.276 ENSMUST00000165563.1
ENSMUST00000020311.6
ENSMUST00000179709.1
ENSMUST00000092508.5
Micu1



mitochondrial calcium uptake 1



chr9_-_108428484 0.274 ENSMUST00000076592.2
Ccdc36
coiled-coil domain containing 36
chr4_+_24898080 0.273 ENSMUST00000029925.3
ENSMUST00000151249.1
Ndufaf4

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 4

chr12_-_115790884 0.270 ENSMUST00000081809.5
Ighv1-73
immunoglobulin heavy variable 1-73
chr8_-_26015577 0.267 ENSMUST00000016138.9
Fnta
farnesyltransferase, CAAX box, alpha
chr11_-_72215592 0.264 ENSMUST00000021157.8
Med31
mediator of RNA polymerase II transcription, subunit 31 homolog (yeast)
chr13_+_85189433 0.263 ENSMUST00000165077.1
ENSMUST00000164127.1
ENSMUST00000163600.1
Ccnh


cyclin H


chr14_+_105258673 0.261 ENSMUST00000136040.2
Ndfip2
Nedd4 family interacting protein 2
chr7_+_127573529 0.261 ENSMUST00000121004.1
Phkg2
phosphorylase kinase, gamma 2 (testis)
chr16_-_17838173 0.260 ENSMUST00000118960.1
Car15
carbonic anhydrase 15
chr14_+_105258573 0.260 ENSMUST00000181969.1
Ndfip2
Nedd4 family interacting protein 2
chr9_-_112232449 0.260 ENSMUST00000035085.5
Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr1_+_4857760 0.260 ENSMUST00000081551.7
Tcea1
transcription elongation factor A (SII) 1
chr4_+_119195496 0.260 ENSMUST00000097908.3
Ccdc23
coiled-coil domain containing 23
chr6_-_131247342 0.259 ENSMUST00000032306.8
ENSMUST00000088867.6
Klra2

killer cell lectin-like receptor, subfamily A, member 2

chr4_-_136898803 0.257 ENSMUST00000046285.5
C1qa
complement component 1, q subcomponent, alpha polypeptide
chr10_+_29313500 0.255 ENSMUST00000020034.4
Echdc1
enoyl Coenzyme A hydratase domain containing 1
chr17_+_21691860 0.254 ENSMUST00000072133.4
Gm10226
predicted gene 10226
chr1_+_75168631 0.253 ENSMUST00000162768.1
ENSMUST00000160439.1
ENSMUST00000027394.5
Zfand2b


zinc finger, AN1 type domain 2B


chr4_-_98823840 0.252 ENSMUST00000097964.2
I0C0044D17Rik
RIKEN cDNA I0C0044D17 gene
chr8_-_104641666 0.252 ENSMUST00000093234.4
Fam96b
family with sequence similarity 96, member B
chr6_-_86684510 0.252 ENSMUST00000001186.4
ENSMUST00000113683.1
Snrnp27

small nuclear ribonucleoprotein 27 (U4/U6.U5)

chr17_+_91236787 0.250 ENSMUST00000057074.8
Gm6741
predicted gene 6741
chr1_-_137969213 0.248 ENSMUST00000182680.1
ENSMUST00000182424.1
Gm26936

predicted gene, 26936

chr13_-_23562369 0.247 ENSMUST00000105107.1
Hist1h3e
histone cluster 1, H3e
chr3_-_88951146 0.247 ENSMUST00000173135.1
Dap3
death associated protein 3
chr16_-_84735742 0.246 ENSMUST00000116584.1
Mrpl39
mitochondrial ribosomal protein L39
chr2_+_68117713 0.245 ENSMUST00000112346.2
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr15_+_43477213 0.245 ENSMUST00000022962.6
Emc2
ER membrane protein complex subunit 2
chr4_-_20778852 0.244 ENSMUST00000102998.3
Nkain3
Na+/K+ transporting ATPase interacting 3
chr10_-_95324072 0.243 ENSMUST00000053594.5
Cradd
CASP2 and RIPK1 domain containing adaptor with death domain
chr18_-_37178493 0.241 ENSMUST00000181887.1
ENSMUST00000180516.1
Gm10544

predicted gene 10544

chr4_+_119195353 0.240 ENSMUST00000106345.2
Ccdc23
coiled-coil domain containing 23
chr2_+_176807362 0.239 ENSMUST00000179435.1
Gm14295
predicted gene 14295
chr10_-_58718210 0.239 ENSMUST00000169859.1
Gm17542
predicted gene, 17542

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 7.8 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.3 1.0 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.3 0.9 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.3 0.8 GO:0060785 regulation of apoptosis involved in tissue homeostasis(GO:0060785)
0.2 0.7 GO:0060129 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.2 1.0 GO:0032382 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373)
0.2 2.4 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.2 0.7 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.2 0.9 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.1 0.4 GO:0043379 memory T cell differentiation(GO:0043379)
0.1 2.5 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.1 0.4 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.4 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103) negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
0.1 0.7 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 2.0 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.1 0.6 GO:0042891 antibiotic transport(GO:0042891) dipeptide transport(GO:0042938)
0.1 0.3 GO:2001180 negative regulation of interleukin-18 production(GO:0032701) negative regulation of interleukin-10 secretion(GO:2001180)
0.1 0.3 GO:0070543 response to linoleic acid(GO:0070543)
0.1 0.6 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 0.3 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.1 0.5 GO:0072008 glomerular mesangial cell differentiation(GO:0072008) glomerular mesangial cell development(GO:0072144)
0.1 1.9 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.1 0.8 GO:0030035 microspike assembly(GO:0030035)
0.1 0.9 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.3 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.1 0.3 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.3 GO:0006982 response to lipid hydroperoxide(GO:0006982) cellular response to lipid hydroperoxide(GO:0071449)
0.1 0.2 GO:0006106 fumarate metabolic process(GO:0006106)
0.1 0.7 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.1 0.2 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.1 1.3 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.4 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 0.3 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.1 0.2 GO:0006507 GPI anchor release(GO:0006507)
0.1 0.2 GO:0051030 snRNA transport(GO:0051030)
0.1 0.2 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700) microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.1 0.7 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 0.4 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.7 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.5 GO:0042435 indole-containing compound biosynthetic process(GO:0042435)
0.1 0.2 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.3 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.1 0.4 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 0.6 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 0.5 GO:0006071 glycerol metabolic process(GO:0006071)
0.1 0.8 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.1 0.4 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 1.1 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.3 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
0.0 0.3 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.9 GO:1901629 regulation of presynaptic membrane organization(GO:1901629)
0.0 0.1 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.0 0.9 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.3 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.6 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.2 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.2 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.3 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.4 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.2 GO:1900272 negative regulation of long-term synaptic potentiation(GO:1900272)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.2 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.0 0.3 GO:0006560 proline metabolic process(GO:0006560)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.6 GO:0046321 positive regulation of fatty acid oxidation(GO:0046321)
0.0 0.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.3 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 1.3 GO:0021591 ventricular system development(GO:0021591)
0.0 0.2 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.9 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.2 GO:0097343 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.4 GO:0006517 protein deglycosylation(GO:0006517)
0.0 0.2 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606) detection of bacterium(GO:0016045) detection of other organism(GO:0098543)
0.0 0.1 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) fatty-acyl-CoA catabolic process(GO:0036115) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 0.2 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.4 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0019389 glucuronoside metabolic process(GO:0019389)
0.0 0.3 GO:0032611 interleukin-1 beta production(GO:0032611)
0.0 0.1 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.2 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.0 GO:0002578 negative regulation of antigen processing and presentation(GO:0002578)
0.0 0.1 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.0 0.1 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.0 0.2 GO:0018065 protein-cofactor linkage(GO:0018065)
0.0 0.1 GO:0071211 protein targeting to vacuole involved in autophagy(GO:0071211)
0.0 0.8 GO:0035456 response to interferon-beta(GO:0035456)
0.0 2.4 GO:0048515 spermatid differentiation(GO:0048515)
0.0 0.1 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.0 0.2 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.3 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.5 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.1 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.1 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.1 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 2.1 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.7 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.1 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.0 1.0 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.2 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.0 0.5 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 1.8 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.2 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.0 0.1 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.2 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.4 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.7 GO:0022904 respiratory electron transport chain(GO:0022904)
0.0 0.3 GO:0018126 protein hydroxylation(GO:0018126)
0.0 0.1 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.2 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.2 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.0 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0 0.6 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.1 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0047484 regulation of response to osmotic stress(GO:0047484)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0000801 central element(GO:0000801)
0.7 7.8 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 0.7 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.2 0.8 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.2 1.3 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.7 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 1.0 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 1.8 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.7 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 1.2 GO:0005687 U4 snRNP(GO:0005687)
0.1 0.3 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 0.3 GO:0070985 TFIIK complex(GO:0070985)
0.1 0.3 GO:0097450 astrocyte end-foot(GO:0097450)
0.1 0.6 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 0.8 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.2 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 0.7 GO:0061574 ASAP complex(GO:0061574)
0.1 0.4 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.9 GO:0046930 pore complex(GO:0046930)
0.1 0.9 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.6 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 0.3 GO:0097361 CIA complex(GO:0097361)
0.1 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.4 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.2 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.3 GO:0070847 core mediator complex(GO:0070847)
0.0 0.9 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.4 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 0.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.9 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.1 GO:0043512 inhibin A complex(GO:0043512)
0.0 0.5 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 1.6 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 1.8 GO:0000786 nucleosome(GO:0000786)
0.0 1.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.4 GO:0002080 acrosomal membrane(GO:0002080)
0.0 1.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088) intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.0 0.1 GO:0097422 tubular endosome(GO:0097422)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 6.4 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.9 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.2 GO:0097542 ciliary tip(GO:0097542)
0.0 1.7 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.0 0.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.2 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0 0.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.6 1.8 GO:0070052 collagen V binding(GO:0070052)
0.5 7.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.3 2.4 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.3 0.8 GO:0072541 peroxynitrite reductase activity(GO:0072541)
0.2 1.0 GO:0050632 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
0.2 0.8 GO:0031720 haptoglobin binding(GO:0031720)
0.2 0.6 GO:0042936 dipeptide transporter activity(GO:0042936)
0.2 1.9 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.2 0.8 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 0.4 GO:0051870 methotrexate binding(GO:0051870)
0.1 3.0 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.4 GO:0004568 chitinase activity(GO:0004568)
0.1 0.4 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.1 0.4 GO:0097677 STAT family protein binding(GO:0097677)
0.1 0.9 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.9 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.8 GO:0043199 sulfate binding(GO:0043199)
0.1 0.4 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.1 0.4 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.1 0.3 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.7 GO:0019211 phosphatase activator activity(GO:0019211)
0.1 0.6 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 0.7 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 0.8 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 0.3 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 0.3 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.1 0.3 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 1.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 0.3 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 0.3 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.1 0.4 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 0.9 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.2 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 0.4 GO:0019841 retinol binding(GO:0019841)
0.1 0.2 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.1 0.9 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 1.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.2 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.1 0.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.2 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.1 0.5 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.3 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.4 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.5 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 1.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.7 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.2 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0033883 pyridoxal phosphatase activity(GO:0033883)
0.0 0.7 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.3 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.0 0.4 GO:0001848 complement binding(GO:0001848)
0.0 0.2 GO:0043176 amine binding(GO:0043176)
0.0 0.2 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.3 GO:0022842 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 1.3 GO:0043022 ribosome binding(GO:0043022)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.4 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.3 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 2.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.9 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.0 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.0 0.3 GO:0071949 FAD binding(GO:0071949)
0.0 0.5 GO:0050699 WW domain binding(GO:0050699)
0.0 0.3 GO:1900750 glutathione peroxidase activity(GO:0004602) glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.2 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.6 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.1 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.0 GO:1903135 cupric ion binding(GO:1903135)
0.0 0.5 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.0 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.2 GO:0045505 dynein intermediate chain binding(GO:0045505)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.8 NABA_COLLAGENS Genes encoding collagen proteins
0.1 0.9 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 2.4 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.1 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 0.7 PID_BMP_PATHWAY BMP receptor signaling
0.0 0.2 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.0 0.2 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.0 0.8 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.1 ST_STAT3_PATHWAY STAT3 Pathway
0.0 0.3 PID_TRAIL_PATHWAY TRAIL signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.9 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.2 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.1 1.7 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 0.9 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.1 1.3 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 0.4 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.1 1.0 REACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM Genes involved in Bile acid and bile salt metabolism
0.0 1.1 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.0 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.2 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.0 0.3 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.5 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.0 2.7 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 2.0 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.5 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.7 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.4 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.1 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.0 0.7 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 2.6 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 0.2 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.1 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.3 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.5 REACTOME_FORMATION_OF_TRANSCRIPTION_COUPLED_NER_TC_NER_REPAIR_COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.1 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.2 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.3 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.1 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.3 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 0.4 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.1 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.1 REACTOME_CDT1_ASSOCIATION_WITH_THE_CDC6_ORC_ORIGIN_COMPLEX Genes involved in CDT1 association with the CDC6:ORC:origin complex
0.0 0.1 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.2 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.8 REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 1.8 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1