Motif ID: Onecut2_Onecut3

Z-value: 0.778

Transcription factors associated with Onecut2_Onecut3:

Gene SymbolEntrez IDGene Name
Onecut2 ENSMUSG00000045991.12 Onecut2
Onecut3 ENSMUSG00000045518.8 Onecut3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Onecut3mm10_v2_chr10_+_80494835_804948730.435.1e-03Click!
Onecut2mm10_v2_chr18_+_64340225_64340364-0.163.2e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Onecut2_Onecut3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_23248264 12.682 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr7_-_49636847 8.406 ENSMUST00000032717.6
Dbx1
developing brain homeobox 1
chr12_+_109545390 4.942 ENSMUST00000146701.1
Meg3
maternally expressed 3
chr12_+_109544498 4.285 ENSMUST00000126289.1
Meg3
maternally expressed 3
chr3_+_102010138 3.229 ENSMUST00000066187.4
Nhlh2
nescient helix loop helix 2
chr9_-_86695897 2.785 ENSMUST00000034989.8
Me1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr10_+_69533761 2.586 ENSMUST00000182884.1
Ank3
ankyrin 3, epithelial
chr4_+_109343029 2.473 ENSMUST00000030281.5
Eps15
epidermal growth factor receptor pathway substrate 15
chr10_-_45470201 2.433 ENSMUST00000079390.6
Lin28b
lin-28 homolog B (C. elegans)
chrY_+_897782 2.111 ENSMUST00000055032.7
Kdm5d
lysine (K)-specific demethylase 5D
chr4_+_43384332 2.091 ENSMUST00000136360.1
Rusc2
RUN and SH3 domain containing 2
chr13_-_41273977 1.914 ENSMUST00000163881.1
Gm17364
predicted gene, 17364
chr11_+_46235460 1.912 ENSMUST00000060185.2
Fndc9
fibronectin type III domain containing 9
chr1_-_158958367 1.810 ENSMUST00000159861.2
Pappa2
pappalysin 2
chr6_+_5390387 1.762 ENSMUST00000183358.1
Asb4
ankyrin repeat and SOCS box-containing 4
chr1_-_64121456 1.705 ENSMUST00000142009.1
ENSMUST00000114086.1
Klf7

Kruppel-like factor 7 (ubiquitous)

chr7_-_34655500 1.460 ENSMUST00000032709.1
Kctd15
potassium channel tetramerisation domain containing 15
chr18_+_50030977 1.360 ENSMUST00000145726.1
ENSMUST00000128377.1
Tnfaip8

tumor necrosis factor, alpha-induced protein 8

chr8_-_109251698 1.354 ENSMUST00000079189.3
4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr13_-_56895737 1.349 ENSMUST00000022023.6
ENSMUST00000109871.1
Trpc7

transient receptor potential cation channel, subfamily C, member 7

chr1_-_170215380 1.254 ENSMUST00000027979.7
ENSMUST00000123399.1
Uhmk1

U2AF homology motif (UHM) kinase 1

chr1_+_10993452 1.235 ENSMUST00000027056.5
Prex2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr4_+_145510759 1.233 ENSMUST00000105742.1
ENSMUST00000136309.1
Gm13225

predicted gene 13225

chr15_-_42676967 1.188 ENSMUST00000022921.5
Angpt1
angiopoietin 1
chr12_-_46818749 1.100 ENSMUST00000021438.6
Nova1
neuro-oncological ventral antigen 1
chr3_+_136670076 1.057 ENSMUST00000070198.7
Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr17_+_21566988 1.035 ENSMUST00000088787.5
Zfp948
zinc finger protein 948
chr4_-_97584605 1.029 ENSMUST00000107067.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr4_-_97584612 1.020 ENSMUST00000107068.2
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr3_-_88455735 1.015 ENSMUST00000029700.5
Sema4a
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr16_-_8672145 0.970 ENSMUST00000008537.8
Carhsp1
calcium regulated heat stable protein 1
chr16_-_28929658 0.959 ENSMUST00000100023.1
Mb21d2
Mab-21 domain containing 2
chr4_+_43383449 0.943 ENSMUST00000135216.1
ENSMUST00000152322.1
Rusc2

RUN and SH3 domain containing 2

chr14_+_13454010 0.935 ENSMUST00000112656.2
Synpr
synaptoporin
chr6_-_127769427 0.919 ENSMUST00000032500.8
Prmt8
protein arginine N-methyltransferase 8
chr2_-_174346712 0.882 ENSMUST00000168292.1
Gm20721
predicted gene, 20721
chr10_+_69533803 0.865 ENSMUST00000182155.1
ENSMUST00000183169.1
ENSMUST00000183148.1
Ank3


ankyrin 3, epithelial


chr15_+_39076885 0.845 ENSMUST00000067072.3
Cthrc1
collagen triple helix repeat containing 1
chr1_+_167598450 0.836 ENSMUST00000111386.1
ENSMUST00000111384.1
Rxrg

retinoid X receptor gamma

chr10_-_64090265 0.792 ENSMUST00000105439.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr9_+_53771499 0.777 ENSMUST00000048670.8
Slc35f2
solute carrier family 35, member F2
chr17_-_90088343 0.768 ENSMUST00000173917.1
Nrxn1
neurexin I
chrX_+_142825698 0.736 ENSMUST00000112888.1
Tmem164
transmembrane protein 164
chr17_+_12119274 0.703 ENSMUST00000024594.2
Agpat4
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr10_-_64090241 0.700 ENSMUST00000133588.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr17_-_90455872 0.700 ENSMUST00000174337.1
ENSMUST00000172466.1
Nrxn1

neurexin I

chr3_+_76075583 0.693 ENSMUST00000160261.1
Fstl5
follistatin-like 5
chrX_-_43274786 0.677 ENSMUST00000016294.7
Tenm1
teneurin transmembrane protein 1
chrX_-_111536325 0.657 ENSMUST00000156639.1
Rps6ka6
ribosomal protein S6 kinase polypeptide 6
chr17_+_21657582 0.650 ENSMUST00000039726.7
3110052M02Rik
RIKEN cDNA 3110052M02 gene
chr3_+_135212557 0.645 ENSMUST00000062893.7
Cenpe
centromere protein E
chr7_+_73391160 0.642 ENSMUST00000128471.1
Rgma
RGM domain family, member A
chr1_-_64121389 0.612 ENSMUST00000055001.3
Klf7
Kruppel-like factor 7 (ubiquitous)
chr12_+_88083697 0.597 ENSMUST00000177720.1
Gm16368
predicted pseudogene 16368
chrX_-_95658392 0.594 ENSMUST00000120620.1
Zc4h2
zinc finger, C4H2 domain containing
chr2_-_65567505 0.588 ENSMUST00000100069.2
Scn3a
sodium channel, voltage-gated, type III, alpha
chr13_-_22041352 0.577 ENSMUST00000102977.2
Hist1h4i
histone cluster 1, H4i
chr14_+_13453937 0.562 ENSMUST00000153954.1
Synpr
synaptoporin
chrX_-_95658379 0.547 ENSMUST00000119640.1
Zc4h2
zinc finger, C4H2 domain containing
chr18_+_35771488 0.543 ENSMUST00000170693.1
Ube2d2a
ubiquitin-conjugating enzyme E2D 2A
chr15_-_79328201 0.540 ENSMUST00000173163.1
ENSMUST00000047816.8
ENSMUST00000172403.2
ENSMUST00000173632.1
Pla2g6



phospholipase A2, group VI



chr11_+_108587077 0.531 ENSMUST00000146912.2
Cep112
centrosomal protein 112
chr18_+_35771574 0.523 ENSMUST00000167406.1
Ube2d2a
ubiquitin-conjugating enzyme E2D 2A
chr3_+_136670679 0.519 ENSMUST00000056758.8
Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr2_+_55411790 0.519 ENSMUST00000155997.1
ENSMUST00000128307.1
Gm14033

predicted gene 14033

chr13_-_102906046 0.479 ENSMUST00000171791.1
Mast4
microtubule associated serine/threonine kinase family member 4
chrX_-_95658416 0.444 ENSMUST00000044382.6
Zc4h2
zinc finger, C4H2 domain containing
chr6_-_92481343 0.442 ENSMUST00000113445.1
Prickle2
prickle homolog 2 (Drosophila)
chrX_+_106015699 0.442 ENSMUST00000033582.4
Cox7b
cytochrome c oxidase subunit VIIb
chr6_+_134640940 0.439 ENSMUST00000062755.8
Loh12cr1
loss of heterozygosity, 12, chromosomal region 1 homolog (human)
chr2_+_38339258 0.435 ENSMUST00000143783.2
Lhx2
LIM homeobox protein 2
chr15_-_79328154 0.434 ENSMUST00000166977.2
Pla2g6
phospholipase A2, group VI
chr11_-_103017167 0.432 ENSMUST00000021313.2
Dcakd
dephospho-CoA kinase domain containing
chr12_+_108605757 0.429 ENSMUST00000109854.2
Evl
Ena-vasodilator stimulated phosphoprotein
chr10_+_128015157 0.425 ENSMUST00000178041.1
ENSMUST00000026461.7
Prim1

DNA primase, p49 subunit

chr13_+_14613242 0.412 ENSMUST00000170836.2
Psma2
proteasome (prosome, macropain) subunit, alpha type 2
chr6_-_85902528 0.403 ENSMUST00000159755.1
1700019G17Rik
RIKEN cDNA 1700019G17 gene
chr12_+_74297474 0.386 ENSMUST00000072100.3
Dbpht2
DNA binding protein with his-thr domain
chr1_-_9944103 0.378 ENSMUST00000182498.1
ENSMUST00000182742.1
ENSMUST00000182580.1
Snhg6


small nucleolar RNA host gene (non-protein coding) 6


chr5_-_23616528 0.375 ENSMUST00000088392.4
Srpk2
serine/arginine-rich protein specific kinase 2
chr1_-_144177259 0.366 ENSMUST00000111941.1
ENSMUST00000052375.1
Rgs13

regulator of G-protein signaling 13

chr7_-_116084635 0.361 ENSMUST00000111755.3
Gm4353
predicted gene 4353
chr17_+_79051906 0.361 ENSMUST00000040789.4
Qpct
glutaminyl-peptide cyclotransferase (glutaminyl cyclase)
chrX_+_119927196 0.356 ENSMUST00000040961.2
ENSMUST00000113366.1
Pabpc5

poly(A) binding protein, cytoplasmic 5

chr3_+_5218516 0.340 ENSMUST00000175866.1
Zfhx4
zinc finger homeodomain 4
chr6_-_42324640 0.336 ENSMUST00000031891.8
ENSMUST00000143278.1
Fam131b

family with sequence similarity 131, member B

chr1_+_167598384 0.335 ENSMUST00000015987.3
Rxrg
retinoid X receptor gamma
chr13_-_14613017 0.335 ENSMUST00000015816.3
Mrpl32
mitochondrial ribosomal protein L32
chr3_+_138143846 0.323 ENSMUST00000159481.1
Trmt10a
tRNA methyltransferase 10A
chr9_-_64253617 0.322 ENSMUST00000005066.8
Map2k1
mitogen-activated protein kinase kinase 1
chr12_+_59131473 0.321 ENSMUST00000177162.1
Ctage5
CTAGE family, member 5
chr7_-_90475971 0.318 ENSMUST00000032843.7
Tmem126b
transmembrane protein 126B
chr2_+_144599897 0.317 ENSMUST00000028917.6
Dtd1
D-tyrosyl-tRNA deacylase 1
chr5_-_17849783 0.315 ENSMUST00000170051.1
ENSMUST00000165232.1
Cd36

CD36 antigen

chr6_-_42324554 0.311 ENSMUST00000095974.3
Fam131b
family with sequence similarity 131, member B
chrX_+_163911401 0.295 ENSMUST00000140845.1
Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr9_-_14782964 0.294 ENSMUST00000034406.3
Ankrd49
ankyrin repeat domain 49
chr12_+_76765527 0.291 ENSMUST00000137826.1
ENSMUST00000041262.7
ENSMUST00000126408.1
ENSMUST00000110399.2
Fntb
Churc1


farnesyltransferase, CAAX box, beta
churchill domain containing 1


chr5_+_29735688 0.288 ENSMUST00000008733.8
Dnajb6
DnaJ (Hsp40) homolog, subfamily B, member 6
chr10_-_61979073 0.267 ENSMUST00000105453.1
ENSMUST00000105452.2
ENSMUST00000105454.2
Col13a1


collagen, type XIII, alpha 1


chr10_+_37139558 0.260 ENSMUST00000062667.3
5930403N24Rik
RIKEN cDNA 5930403N24 gene
chr7_+_35802593 0.258 ENSMUST00000052454.2
E130304I02Rik
RIKEN cDNA E130304I02 gene
chr18_-_53744509 0.255 ENSMUST00000049811.6
Cep120
centrosomal protein 120
chr15_+_102459028 0.253 ENSMUST00000164938.1
ENSMUST00000023810.5
Prr13

proline rich 13

chr12_+_59131286 0.252 ENSMUST00000176464.1
ENSMUST00000170992.2
ENSMUST00000176322.1
Ctage5


CTAGE family, member 5


chr2_+_36049453 0.250 ENSMUST00000028256.4
Morn5
MORN repeat containing 5
chr10_+_128790903 0.247 ENSMUST00000026411.6
Mmp19
matrix metallopeptidase 19
chr16_-_4679703 0.245 ENSMUST00000038552.6
ENSMUST00000090480.4
Coro7

coronin 7

chr5_+_32458974 0.242 ENSMUST00000015100.8
Ppp1cb
protein phosphatase 1, catalytic subunit, beta isoform
chr9_+_65890237 0.238 ENSMUST00000045802.6
2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr15_+_102459193 0.237 ENSMUST00000164957.1
ENSMUST00000171245.1
Prr13

proline rich 13

chr13_+_66904914 0.234 ENSMUST00000168767.2
Gm10767
predicted gene 10767
chr5_+_109940426 0.233 ENSMUST00000170826.1
Gm15446
predicted gene 15446
chr5_-_52566264 0.232 ENSMUST00000039750.5
Lgi2
leucine-rich repeat LGI family, member 2
chr9_-_20728219 0.223 ENSMUST00000034692.7
Olfm2
olfactomedin 2
chr10_-_53647080 0.219 ENSMUST00000169866.1
Fam184a
family with sequence similarity 184, member A
chr18_-_10030017 0.216 ENSMUST00000116669.1
ENSMUST00000092096.6
Usp14

ubiquitin specific peptidase 14

chr6_-_51469869 0.215 ENSMUST00000114459.1
ENSMUST00000069949.6
Hnrnpa2b1

heterogeneous nuclear ribonucleoprotein A2/B1

chr1_+_49244616 0.210 ENSMUST00000056879.8
C230029F24Rik
RIKEN cDNA C230029F24 gene
chrX_-_113185485 0.210 ENSMUST00000026607.8
ENSMUST00000113388.2
Chm

choroidermia

chr9_+_55326913 0.208 ENSMUST00000085754.3
ENSMUST00000034862.4
AI118078

expressed sequence AI118078

chr3_+_138143888 0.205 ENSMUST00000161141.1
Trmt10a
tRNA methyltransferase 10A
chr19_+_44992127 0.204 ENSMUST00000179305.1
Sema4g
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr7_+_19291070 0.199 ENSMUST00000108468.3
Rtn2
reticulon 2 (Z-band associated protein)
chr17_-_71459300 0.194 ENSMUST00000183937.1
Gm4707
predicted gene 4707
chr14_+_113314602 0.191 ENSMUST00000072359.6
Tpm3-rs7
tropomyosin 3, related sequence 7
chr18_+_56707725 0.185 ENSMUST00000025486.8
Lmnb1
lamin B1
chr7_+_119760918 0.185 ENSMUST00000106527.1
ENSMUST00000106528.1
ENSMUST00000063770.3
ENSMUST00000106529.1
Acsm3



acyl-CoA synthetase medium-chain family member 3



chr9_-_108428484 0.184 ENSMUST00000076592.2
Ccdc36
coiled-coil domain containing 36
chr13_+_90923122 0.179 ENSMUST00000051955.7
Rps23
ribosomal protein S23
chr15_+_92597104 0.177 ENSMUST00000035399.8
Pdzrn4
PDZ domain containing RING finger 4
chr8_+_4625840 0.172 ENSMUST00000073201.5
Zfp958
zinc finger protein 958
chr17_-_33033367 0.171 ENSMUST00000087654.4
Zfp763
zinc finger protein 763
chr7_-_89941084 0.165 ENSMUST00000075010.4
ENSMUST00000153470.1
l7Rn6

lethal, Chr 7, Rinchik 6

chr11_+_97315716 0.159 ENSMUST00000019026.3
ENSMUST00000132168.1
Mrpl45

mitochondrial ribosomal protein L45

chr6_-_115037824 0.154 ENSMUST00000174848.1
ENSMUST00000032461.5
Tamm41

TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae)

chr2_-_25224653 0.151 ENSMUST00000043584.4
Tubb4b
tubulin, beta 4B class IVB
chr6_+_48684544 0.151 ENSMUST00000118802.1
Gimap4
GTPase, IMAP family member 4
chr3_+_106034661 0.147 ENSMUST00000170669.2
Gm4540
predicted gene 4540
chr19_+_60144682 0.147 ENSMUST00000065383.4
E330013P04Rik
RIKEN cDNA E330013P04 gene
chr14_+_47472547 0.147 ENSMUST00000168833.1
ENSMUST00000163324.1
ENSMUST00000043112.7
Fbxo34


F-box protein 34


chr3_-_19265007 0.143 ENSMUST00000091314.4
Pde7a
phosphodiesterase 7A
chr9_-_69451035 0.128 ENSMUST00000071565.5
Gm4978
predicted gene 4978
chr15_+_55112317 0.117 ENSMUST00000096433.3
Deptor
DEP domain containing MTOR-interacting protein
chr2_-_128943985 0.114 ENSMUST00000028866.8
Zc3h8
zinc finger CCCH type containing 8
chr16_-_56712825 0.113 ENSMUST00000136394.1
Tfg
Trk-fused gene
chr6_+_127233756 0.105 ENSMUST00000071458.3
Gm4968
predicted gene 4968
chr14_+_47472628 0.104 ENSMUST00000095941.2
Fbxo34
F-box protein 34
chr9_+_75051977 0.101 ENSMUST00000170310.1
ENSMUST00000166549.1
Arpp19

cAMP-regulated phosphoprotein 19

chr4_-_109156610 0.099 ENSMUST00000161363.1
Osbpl9
oxysterol binding protein-like 9
chr6_+_48684570 0.099 ENSMUST00000067506.7
ENSMUST00000119575.1
ENSMUST00000114527.2
ENSMUST00000121957.1
ENSMUST00000090070.5
Gimap4




GTPase, IMAP family member 4




chr10_-_42018363 0.098 ENSMUST00000162405.1
ENSMUST00000095729.4
ENSMUST00000161081.1
ENSMUST00000160262.2
Armc2



armadillo repeat containing 2



chr17_+_29274078 0.093 ENSMUST00000149405.2
BC004004
cDNA sequence BC004004
chr14_+_11227511 0.092 ENSMUST00000080237.3
Rpl21-ps4
ribosomal protein L21, pseudogene 4
chr2_+_144594054 0.091 ENSMUST00000136628.1
Gm561
predicted gene 561
chr7_-_89941196 0.088 ENSMUST00000117354.1
l7Rn6
lethal, Chr 7, Rinchik 6
chr12_-_82496537 0.084 ENSMUST00000179295.1
Gm5435
predicted gene 5435
chr4_+_155831272 0.084 ENSMUST00000139651.1
ENSMUST00000084097.5
Aurkaip1

aurora kinase A interacting protein 1

chr16_+_4741543 0.083 ENSMUST00000120232.1
Hmox2
heme oxygenase (decycling) 2
chr8_-_71671723 0.079 ENSMUST00000177517.1
ENSMUST00000030170.8
Unc13a

unc-13 homolog A (C. elegans)

chr8_+_93810832 0.075 ENSMUST00000034198.8
ENSMUST00000125716.1
Gnao1

guanine nucleotide binding protein, alpha O

chr17_+_34564268 0.069 ENSMUST00000015612.7
Notch4
notch 4
chr6_-_51469836 0.065 ENSMUST00000090002.7
Hnrnpa2b1
heterogeneous nuclear ribonucleoprotein A2/B1
chr14_-_20181773 0.065 ENSMUST00000024011.8
Kcnk5
potassium channel, subfamily K, member 5
chr3_+_5218589 0.062 ENSMUST00000177488.1
Zfhx4
zinc finger homeodomain 4
chr7_+_19119853 0.060 ENSMUST00000053109.3
Fbxo46
F-box protein 46
chr2_-_79428891 0.050 ENSMUST00000143974.1
Cerkl
ceramide kinase-like
chrX_+_42151002 0.050 ENSMUST00000123245.1
Stag2
stromal antigen 2
chr1_-_63114516 0.041 ENSMUST00000097718.2
Ino80d
INO80 complex subunit D
chrX_-_150657392 0.037 ENSMUST00000151403.2
ENSMUST00000087253.4
ENSMUST00000112709.1
ENSMUST00000163969.1
ENSMUST00000087258.3
Tro




trophinin




chr5_-_147894804 0.035 ENSMUST00000118527.1
ENSMUST00000031655.3
ENSMUST00000138244.1
Slc46a3


solute carrier family 46, member 3


chr11_+_74830920 0.032 ENSMUST00000000291.2
Mnt
max binding protein
chr2_+_104069819 0.022 ENSMUST00000111131.2
ENSMUST00000111132.1
ENSMUST00000129749.1
Cd59b


CD59b antigen


chr1_+_153749414 0.022 ENSMUST00000086209.3
Rnasel
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
chr3_-_63851251 0.021 ENSMUST00000162269.2
ENSMUST00000159676.2
ENSMUST00000175947.1
Plch1


phospholipase C, eta 1


chr1_+_88103229 0.009 ENSMUST00000113135.3
ENSMUST00000113138.1
Ugt1a6a
Ugt1a6b
UDP glucuronosyltransferase 1 family, polypeptide A6A
UDP glucuronosyltransferase 1 family, polypeptide A6B
chr2_-_51149100 0.008 ENSMUST00000154545.1
ENSMUST00000017288.2
Rnd3

Rho family GTPase 3

chr6_+_127453705 0.004 ENSMUST00000039680.5
Parp11
poly (ADP-ribose) polymerase family, member 11

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 12.7 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.6 2.8 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.5 1.6 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) regulation of connective tissue replacement(GO:1905203)
0.5 8.4 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.4 2.1 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.4 1.2 GO:0030210 heparin biosynthetic process(GO:0030210) Tie signaling pathway(GO:0048014)
0.4 1.5 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
0.3 9.1 GO:0008340 determination of adult lifespan(GO:0008340)
0.3 3.2 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.3 2.4 GO:0010587 miRNA catabolic process(GO:0010587)
0.2 2.5 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.2 1.0 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.2 0.9 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.2 1.8 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.1 0.4 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.1 0.4 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.1 0.6 GO:0046684 response to pyrethroid(GO:0046684)
0.1 3.2 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.1 0.4 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.3 GO:0070543 response to linoleic acid(GO:0070543)
0.1 1.5 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.1 0.6 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.1 0.4 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.3 GO:0018343 protein farnesylation(GO:0018343)
0.1 0.2 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1 0.3 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.1 0.4 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 1.3 GO:0006828 manganese ion transport(GO:0006828)
0.1 0.2 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
0.1 0.6 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.1 1.3 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.1 0.1 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.1 0.7 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 1.0 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.3 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.0 0.2 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.8 GO:0090177 establishment of planar polarity involved in neural tube closure(GO:0090177)
0.0 0.3 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.4 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 1.0 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.6 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.3 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 1.4 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.5 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.4 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 1.4 GO:0032611 interleukin-1 beta production(GO:0032611)
0.0 0.2 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.3 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.0 0.2 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.1 GO:0006788 heme oxidation(GO:0006788)
0.0 0.2 GO:0050919 negative chemotaxis(GO:0050919)
0.0 2.1 GO:0060349 bone morphogenesis(GO:0060349)
0.0 0.2 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.7 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 1.1 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.1 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.1 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.0 0.1 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.0 2.3 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.5 GO:0097120 receptor localization to synapse(GO:0097120)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.3 1.6 GO:0005955 calcineurin complex(GO:0005955)
0.2 2.5 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.2 3.2 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 1.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 1.3 GO:0089701 U2AF(GO:0089701)
0.1 1.0 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.1 0.3 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 0.4 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.1 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.1 1.5 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.2 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.6 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.4 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.4 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.3 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 1.3 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.5 GO:0060077 inhibitory synapse(GO:0060077)
0.0 1.1 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0045298 tubulin complex(GO:0045298)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.3 2.1 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.3 1.6 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2 0.9 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1 0.4 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.1 0.6 GO:0043515 kinetochore binding(GO:0043515)
0.1 1.5 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 1.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 1.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.3 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 1.0 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 0.3 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 1.3 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 1.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 0.5 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 0.2 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.1 3.2 GO:0030507 spectrin binding(GO:0030507)
0.1 3.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 10.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 0.2 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.3 GO:0001069 regulatory region RNA binding(GO:0001069) mRNA CDS binding(GO:1990715)
0.0 2.5 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 1.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.7 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 1.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.6 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.6 GO:0031402 sodium ion binding(GO:0031402)
0.0 0.8 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.4 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.0 2.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.1 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.3 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.4 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 2.8 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.1 GO:0001729 ceramide kinase activity(GO:0001729)
0.0 0.1 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.2 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 1.4 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.4 GO:0071889 14-3-3 protein binding(GO:0071889)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 2.5 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 1.2 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.8 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.3 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.2 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 2.2 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.2 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 0.9 PID_PLK1_PATHWAY PLK1 signaling events
0.0 0.6 PID_BMP_PATHWAY BMP receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 1.4 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 3.2 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.0 REACTOME_ACYL_CHAIN_REMODELLING_OF_PC Genes involved in Acyl chain remodelling of PC
0.1 1.2 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.1 2.5 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.1 0.4 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 1.6 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.7 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.7 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 2.9 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.7 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.0 0.4 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.3 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.6 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.2 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.6 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.7 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway