Motif ID: Zkscan1
Z-value: 0.523

Transcription factors associated with Zkscan1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Zkscan1 | ENSMUSG00000029729.6 | Zkscan1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Zkscan1 | mm10_v2_chr5_+_138085083_138085147 | -0.05 | 7.5e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 2.9 | GO:0010626 | negative regulation of Schwann cell proliferation(GO:0010626) |
0.5 | 2.0 | GO:0006776 | vitamin A metabolic process(GO:0006776) |
0.4 | 1.3 | GO:0060129 | thyroid-stimulating hormone-secreting cell differentiation(GO:0060129) |
0.3 | 1.3 | GO:0070858 | negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252) |
0.3 | 1.9 | GO:1901164 | negative regulation of trophoblast cell migration(GO:1901164) |
0.2 | 0.4 | GO:0050883 | musculoskeletal movement, spinal reflex action(GO:0050883) |
0.2 | 0.5 | GO:1902396 | protein localization to bicellular tight junction(GO:1902396) |
0.2 | 0.5 | GO:0021577 | hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) |
0.2 | 0.5 | GO:2001180 | negative regulation of interleukin-18 production(GO:0032701) negative regulation of interleukin-10 secretion(GO:2001180) |
0.2 | 0.5 | GO:0042732 | D-xylose metabolic process(GO:0042732) |
0.2 | 2.4 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
0.2 | 0.5 | GO:1901052 | sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053) |
0.2 | 0.5 | GO:0006419 | alanyl-tRNA aminoacylation(GO:0006419) |
0.1 | 0.6 | GO:0010735 | positive regulation of transcription via serum response element binding(GO:0010735) |
0.1 | 0.4 | GO:1904760 | myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760) |
0.1 | 1.2 | GO:0097011 | cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) |
0.1 | 0.3 | GO:0035880 | embryonic nail plate morphogenesis(GO:0035880) positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364) |
0.1 | 1.2 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
0.1 | 0.3 | GO:0060023 | soft palate development(GO:0060023) |
0.1 | 0.4 | GO:0086046 | membrane depolarization during SA node cell action potential(GO:0086046) |
0.1 | 0.6 | GO:0060753 | regulation of mast cell chemotaxis(GO:0060753) |
0.1 | 1.3 | GO:0046033 | AMP metabolic process(GO:0046033) |
0.1 | 0.6 | GO:0046541 | stabilization of membrane potential(GO:0030322) saliva secretion(GO:0046541) positive regulation of T cell receptor signaling pathway(GO:0050862) |
0.1 | 0.3 | GO:0000454 | snoRNA guided rRNA pseudouridine synthesis(GO:0000454) |
0.1 | 0.7 | GO:0070307 | lens fiber cell development(GO:0070307) |
0.0 | 0.9 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
0.0 | 0.8 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
0.0 | 0.9 | GO:0009950 | dorsal/ventral axis specification(GO:0009950) |
0.0 | 0.1 | GO:0097500 | receptor localization to nonmotile primary cilium(GO:0097500) |
0.0 | 0.3 | GO:0032074 | negative regulation of nuclease activity(GO:0032074) |
0.0 | 0.8 | GO:0038092 | nodal signaling pathway(GO:0038092) |
0.0 | 0.6 | GO:0007398 | ectoderm development(GO:0007398) |
0.0 | 0.9 | GO:0032967 | positive regulation of collagen biosynthetic process(GO:0032967) |
0.0 | 0.6 | GO:0042711 | maternal behavior(GO:0042711) |
0.0 | 0.1 | GO:0090235 | regulation of metaphase plate congression(GO:0090235) |
0.0 | 0.3 | GO:0060732 | positive regulation of inositol phosphate biosynthetic process(GO:0060732) |
0.0 | 0.2 | GO:0001731 | formation of translation preinitiation complex(GO:0001731) |
0.0 | 0.1 | GO:0048630 | skeletal muscle tissue growth(GO:0048630) |
0.0 | 1.0 | GO:0032418 | lysosome localization(GO:0032418) |
0.0 | 0.1 | GO:0048251 | elastic fiber assembly(GO:0048251) |
0.0 | 0.4 | GO:0030513 | positive regulation of BMP signaling pathway(GO:0030513) |
0.0 | 0.4 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 2.9 | GO:0031315 | extrinsic component of mitochondrial outer membrane(GO:0031315) |
0.3 | 0.9 | GO:0038045 | large latent transforming growth factor-beta complex(GO:0038045) |
0.1 | 2.7 | GO:0005682 | U5 snRNP(GO:0005682) |
0.1 | 0.8 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
0.1 | 0.8 | GO:0000796 | condensin complex(GO:0000796) |
0.1 | 0.3 | GO:0090661 | box H/ACA telomerase RNP complex(GO:0090661) |
0.1 | 1.0 | GO:0031083 | BLOC-1 complex(GO:0031083) |
0.1 | 0.2 | GO:0071595 | Nem1-Spo7 phosphatase complex(GO:0071595) |
0.0 | 0.4 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
0.0 | 0.2 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
0.0 | 0.5 | GO:0031143 | pseudopodium(GO:0031143) |
0.0 | 0.2 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
0.0 | 0.2 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
0.0 | 2.4 | GO:0000118 | histone deacetylase complex(GO:0000118) |
0.0 | 0.4 | GO:0005849 | mRNA cleavage factor complex(GO:0005849) |
0.0 | 0.1 | GO:0016012 | sarcoglycan complex(GO:0016012) |
0.0 | 0.1 | GO:0034464 | BBSome(GO:0034464) |
0.0 | 0.1 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
0.0 | 1.1 | GO:0005604 | basement membrane(GO:0005604) |
0.0 | 0.7 | GO:0005882 | intermediate filament(GO:0005882) |
0.0 | 0.2 | GO:0008305 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 1.3 | GO:0005105 | type 1 fibroblast growth factor receptor binding(GO:0005105) |
0.4 | 1.3 | GO:0046899 | nucleoside triphosphate adenylate kinase activity(GO:0046899) |
0.3 | 2.0 | GO:0019841 | retinol binding(GO:0019841) |
0.2 | 0.9 | GO:0050436 | microfibril binding(GO:0050436) |
0.2 | 0.6 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
0.2 | 0.5 | GO:0046997 | sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997) |
0.2 | 0.5 | GO:0004813 | alanine-tRNA ligase activity(GO:0004813) |
0.1 | 0.4 | GO:0001591 | dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591) |
0.1 | 1.4 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
0.1 | 0.9 | GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162) |
0.1 | 2.9 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
0.1 | 0.7 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.1 | 1.3 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
0.1 | 0.2 | GO:0036132 | 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522) |
0.1 | 0.2 | GO:0098639 | collagen binding involved in cell-matrix adhesion(GO:0098639) |
0.0 | 0.4 | GO:0086007 | voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007) |
0.0 | 0.3 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
0.0 | 0.4 | GO:0008430 | selenium binding(GO:0008430) |
0.0 | 0.2 | GO:0033592 | RNA strand annealing activity(GO:0033592) |
0.0 | 0.1 | GO:0004720 | protein-lysine 6-oxidase activity(GO:0004720) |
0.0 | 0.6 | GO:0071949 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) FAD binding(GO:0071949) |
0.0 | 1.2 | GO:0004896 | cytokine receptor activity(GO:0004896) |
0.0 | 0.4 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
0.0 | 0.3 | GO:0019104 | DNA N-glycosylase activity(GO:0019104) |
0.0 | 1.2 | GO:0046875 | ephrin receptor binding(GO:0046875) |
0.0 | 0.4 | GO:0050811 | GABA-A receptor activity(GO:0004890) GABA receptor binding(GO:0050811) |
0.0 | 0.8 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
0.0 | 0.5 | GO:0042169 | SH2 domain binding(GO:0042169) |
0.0 | 0.4 | GO:0001223 | transcription coactivator binding(GO:0001223) |
0.0 | 0.5 | GO:0019200 | carbohydrate kinase activity(GO:0019200) |
0.0 | 0.1 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
0.0 | 0.6 | GO:0042974 | retinoic acid receptor binding(GO:0042974) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 1.1 | PID_INTEGRIN_A9B1_PATHWAY | Alpha9 beta1 integrin signaling events |
0.0 | 2.1 | PID_RETINOIC_ACID_PATHWAY | Retinoic acid receptors-mediated signaling |
0.0 | 1.9 | PID_IL6_7_PATHWAY | IL6-mediated signaling events |
0.0 | 1.3 | PID_FGF_PATHWAY | FGF signaling pathway |
0.0 | 0.3 | PID_INTEGRIN2_PATHWAY | Beta2 integrin cell surface interactions |
0.0 | 0.6 | PID_MYC_PATHWAY | C-MYC pathway |
0.0 | 0.6 | PID_IL8_CXCR2_PATHWAY | IL8- and CXCR2-mediated signaling events |
0.0 | 0.5 | PID_REELIN_PATHWAY | Reelin signaling pathway |
0.0 | 0.2 | PID_INTEGRIN_CS_PATHWAY | Integrin family cell surface interactions |
0.0 | 0.7 | PID_ERA_GENOMIC_PATHWAY | Validated nuclear estrogen receptor alpha network |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 1.3 | REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION | Genes involved in FGFR4 ligand binding and activation |
0.1 | 1.9 | REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX | Genes involved in Degradation of the extracellular matrix |
0.1 | 0.3 | REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
0.0 | 1.2 | REACTOME_IL_RECEPTOR_SHC_SIGNALING | Genes involved in Interleukin receptor SHC signaling |
0.0 | 0.4 | REACTOME_AMINE_LIGAND_BINDING_RECEPTORS | Genes involved in Amine ligand-binding receptors |
0.0 | 0.4 | REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
0.0 | 0.5 | REACTOME_NEPHRIN_INTERACTIONS | Genes involved in Nephrin interactions |
0.0 | 0.8 | REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
0.0 | 0.5 | REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
0.0 | 0.6 | REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
0.0 | 0.1 | REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
0.0 | 0.7 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |