Motif ID: Hoxc10

Z-value: 0.659


Transcription factors associated with Hoxc10:

Gene SymbolEntrez IDGene Name
Hoxc10 ENSMUSG00000022484.7 Hoxc10



Activity profile for motif Hoxc10.

activity profile for motif Hoxc10


Sorted Z-values histogram for motif Hoxc10

Sorted Z-values for motif Hoxc10



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxc10

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_159737510 5.610 ENSMUST00000111669.3
Tnr
tenascin R
chr5_+_117841839 5.602 ENSMUST00000142742.2
Nos1
nitric oxide synthase 1, neuronal
chr2_-_25469742 4.766 ENSMUST00000114259.2
ENSMUST00000015234.6
Ptgds

prostaglandin D2 synthase (brain)

chr2_-_25470031 3.873 ENSMUST00000114251.1
Ptgds
prostaglandin D2 synthase (brain)
chr7_-_73537621 3.864 ENSMUST00000172704.1
Chd2
chromodomain helicase DNA binding protein 2
chr13_-_84064772 3.639 ENSMUST00000182477.1
Gm17750
predicted gene, 17750
chr4_+_144893127 3.502 ENSMUST00000142808.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr15_-_58214882 2.568 ENSMUST00000022986.6
Fbxo32
F-box protein 32
chr16_-_23988852 2.554 ENSMUST00000023151.5
Bcl6
B cell leukemia/lymphoma 6
chr5_-_62766153 2.279 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr9_-_44799179 2.125 ENSMUST00000114705.1
ENSMUST00000002100.7
Tmem25

transmembrane protein 25

chr6_-_13839916 2.108 ENSMUST00000060442.7
Gpr85
G protein-coupled receptor 85
chr2_-_144527341 2.062 ENSMUST00000163701.1
ENSMUST00000081982.5
Dzank1

double zinc ribbon and ankyrin repeat domains 1

chr15_+_21111452 1.858 ENSMUST00000075132.6
Cdh12
cadherin 12
chr15_+_81936911 1.648 ENSMUST00000135663.1
Csdc2
cold shock domain containing C2, RNA binding
chr15_+_92597104 1.629 ENSMUST00000035399.8
Pdzrn4
PDZ domain containing RING finger 4
chr15_+_81936753 1.604 ENSMUST00000038757.7
Csdc2
cold shock domain containing C2, RNA binding
chr15_+_100761741 1.558 ENSMUST00000023776.6
Slc4a8
solute carrier family 4 (anion exchanger), member 8
chr18_-_42899470 1.533 ENSMUST00000120632.1
Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr13_+_104287855 1.491 ENSMUST00000065766.6
Adamts6
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 6
chr18_-_42899294 1.375 ENSMUST00000117687.1
Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr8_-_41016295 1.360 ENSMUST00000131965.1
Mtus1
mitochondrial tumor suppressor 1
chr1_+_66386968 1.357 ENSMUST00000145419.1
Map2
microtubule-associated protein 2
chr17_-_90088343 1.295 ENSMUST00000173917.1
Nrxn1
neurexin I
chr3_+_108591279 1.277 ENSMUST00000051145.8
ENSMUST00000139626.1
Wdr47

WD repeat domain 47

chr1_+_179961110 1.225 ENSMUST00000076687.5
ENSMUST00000097450.3
Cdc42bpa

CDC42 binding protein kinase alpha

chr1_+_180111339 1.213 ENSMUST00000145181.1
Cdc42bpa
CDC42 binding protein kinase alpha
chr14_+_13453937 1.187 ENSMUST00000153954.1
Synpr
synaptoporin
chr3_-_146770218 1.169 ENSMUST00000106137.1
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr9_+_113812547 1.116 ENSMUST00000166734.2
ENSMUST00000111838.2
ENSMUST00000163895.2
Clasp2


CLIP associating protein 2


chr14_+_13454010 1.094 ENSMUST00000112656.2
Synpr
synaptoporin
chr1_-_63114255 1.085 ENSMUST00000153992.1
ENSMUST00000165066.1
ENSMUST00000172416.1
ENSMUST00000137511.1
Ino80d



INO80 complex subunit D



chr3_-_49757257 1.072 ENSMUST00000035931.7
Pcdh18
protocadherin 18
chr11_+_29463735 1.054 ENSMUST00000155854.1
Ccdc88a
coiled coil domain containing 88A
chr17_-_91092715 1.050 ENSMUST00000160800.2
ENSMUST00000159778.1
ENSMUST00000160844.3
Nrxn1


neurexin I


chr3_-_123672321 1.022 ENSMUST00000172537.1
ENSMUST00000029602.6
Ndst3

N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3

chr5_+_71699918 1.015 ENSMUST00000031122.7
Gabrb1
gamma-aminobutyric acid (GABA) A receptor, subunit beta 1
chr9_-_116175318 1.001 ENSMUST00000061101.4
ENSMUST00000035014.6
Tgfbr2

transforming growth factor, beta receptor II

chr17_-_35074485 0.999 ENSMUST00000007259.3
Ly6g6d
lymphocyte antigen 6 complex, locus G6D
chr17_+_31433054 0.983 ENSMUST00000136384.1
Pde9a
phosphodiesterase 9A
chr17_-_78684262 0.964 ENSMUST00000145480.1
Strn
striatin, calmodulin binding protein
chr9_+_50575273 0.961 ENSMUST00000059081.6
ENSMUST00000180021.1
Il18

interleukin 18

chr5_-_111761697 0.910 ENSMUST00000129146.1
ENSMUST00000137398.1
ENSMUST00000129065.1
E130006D01Rik


RIKEN cDNA E130006D01 gene


chr7_-_29906087 0.829 ENSMUST00000053521.8
Zfp27
zinc finger protein 27
chr1_+_179960472 0.825 ENSMUST00000097453.2
ENSMUST00000111117.1
Cdc42bpa

CDC42 binding protein kinase alpha

chr8_+_83666827 0.811 ENSMUST00000019608.5
Ptger1
prostaglandin E receptor 1 (subtype EP1)
chr14_+_124005355 0.734 ENSMUST00000166105.1
Gm17615
predicted gene, 17615
chr3_+_32436151 0.709 ENSMUST00000029201.7
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr13_-_41273977 0.689 ENSMUST00000163881.1
Gm17364
predicted gene, 17364
chr1_+_191025350 0.676 ENSMUST00000181050.1
A230020J21Rik
RIKEN cDNA A230020J21 gene
chr2_+_32395896 0.668 ENSMUST00000028162.3
Ptges2
prostaglandin E synthase 2
chr7_+_103550368 0.598 ENSMUST00000106888.1
Olfr613
olfactory receptor 613
chr1_+_127729405 0.548 ENSMUST00000038006.6
Acmsd
amino carboxymuconate semialdehyde decarboxylase
chr4_+_11758147 0.531 ENSMUST00000029871.5
ENSMUST00000108303.1
Cdh17

cadherin 17

chr1_+_17601893 0.530 ENSMUST00000088476.2
Pi15
peptidase inhibitor 15
chr2_-_27463994 0.495 ENSMUST00000164296.1
Brd3
bromodomain containing 3
chr6_-_136875794 0.492 ENSMUST00000032342.1
Mgp
matrix Gla protein
chr18_-_6490808 0.446 ENSMUST00000028100.6
ENSMUST00000050542.5
Epc1

enhancer of polycomb homolog 1 (Drosophila)

chr13_+_24943144 0.436 ENSMUST00000021773.5
Gpld1
glycosylphosphatidylinositol specific phospholipase D1
chr19_-_56548013 0.425 ENSMUST00000182059.1
Dclre1a
DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae)
chr1_-_97761538 0.417 ENSMUST00000171129.1
Ppip5k2
diphosphoinositol pentakisphosphate kinase 2
chr11_-_79504078 0.410 ENSMUST00000164465.2
Omg
oligodendrocyte myelin glycoprotein
chr1_+_194619815 0.374 ENSMUST00000027952.5
Plxna2
plexin A2
chrX_+_169685191 0.347 ENSMUST00000112104.1
ENSMUST00000112107.1
Mid1

midline 1

chr1_-_36244245 0.337 ENSMUST00000046875.7
Uggt1
UDP-glucose glycoprotein glucosyltransferase 1
chr1_-_63114516 0.324 ENSMUST00000097718.2
Ino80d
INO80 complex subunit D
chr8_+_25720054 0.321 ENSMUST00000068916.8
ENSMUST00000139836.1
Ppapdc1b

phosphatidic acid phosphatase type 2 domain containing 1B

chr5_-_62765618 0.318 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr11_-_97700327 0.314 ENSMUST00000018681.7
Pcgf2
polycomb group ring finger 2
chr8_-_47352348 0.313 ENSMUST00000110367.2
Stox2
storkhead box 2
chr15_+_85510812 0.242 ENSMUST00000079690.2
Gm4825
predicted pseudogene 4825
chr13_-_106847267 0.221 ENSMUST00000057427.4
Lrrc70
leucine rich repeat containing 70
chr13_-_107890059 0.219 ENSMUST00000105097.2
Zswim6
zinc finger SWIM-type containing 6
chr19_-_56548122 0.216 ENSMUST00000026063.5
ENSMUST00000182276.1
Dclre1a

DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae)

chr1_-_45503282 0.210 ENSMUST00000086430.4
Col5a2
collagen, type V, alpha 2
chr14_-_54686060 0.204 ENSMUST00000125265.1
Acin1
apoptotic chromatin condensation inducer 1
chr2_+_130576170 0.175 ENSMUST00000028764.5
Oxt
oxytocin
chr19_+_56548254 0.170 ENSMUST00000071423.5
Nhlrc2
NHL repeat containing 2
chr11_+_115933282 0.163 ENSMUST00000140991.1
Sap30bp
SAP30 binding protein
chr8_-_18741542 0.157 ENSMUST00000033846.6
Angpt2
angiopoietin 2
chr9_+_37208291 0.144 ENSMUST00000034632.8
Tmem218
transmembrane protein 218
chr7_-_141435327 0.123 ENSMUST00000138865.1
Slc25a22
solute carrier family 25 (mitochondrial carrier, glutamate), member 22
chr9_-_21287953 0.112 ENSMUST00000184326.1
ENSMUST00000038671.3
Kri1

KRI1 homolog (S. cerevisiae)

chr17_-_46680870 0.100 ENSMUST00000165007.1
ENSMUST00000071841.5
Klhdc3

kelch domain containing 3

chr2_-_32451396 0.066 ENSMUST00000028160.8
ENSMUST00000113310.2
Slc25a25

solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25

chr7_-_141434532 0.065 ENSMUST00000133021.1
ENSMUST00000106007.3
ENSMUST00000150026.1
ENSMUST00000133206.2
Slc25a22



solute carrier family 25 (mitochondrial carrier, glutamate), member 22



chr19_-_7341848 0.064 ENSMUST00000171393.1
Mark2
MAP/microtubule affinity-regulating kinase 2
chr2_+_80315461 0.042 ENSMUST00000028392.7
Dnajc10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr1_-_69108039 0.013 ENSMUST00000121473.1
Erbb4
v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
chr15_+_25773985 0.009 ENSMUST00000125667.1
Myo10
myosin X
chr1_-_63176653 0.007 ENSMUST00000027111.8
ENSMUST00000168099.2
Ndufs1

NADH dehydrogenase (ubiquinone) Fe-S protein 1

chr4_-_110290884 0.002 ENSMUST00000142722.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.6 GO:0099548 drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738) retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by nitric oxide(GO:0099548)
1.7 8.6 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
1.4 5.6 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.9 2.6 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.9 2.6 GO:0043379 memory T cell differentiation(GO:0043379) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.6 2.3 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
0.3 1.0 GO:0003274 tolerance induction to self antigen(GO:0002513) endocardial cushion fusion(GO:0003274)
0.3 1.0 GO:0032817 regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819)
0.3 3.5 GO:0042572 retinol metabolic process(GO:0042572)
0.2 0.7 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.2 2.9 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.2 1.1 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.2 3.9 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.2 0.5 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.2 0.5 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.2 1.0 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.2 1.1 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091) negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 0.4 GO:0002430 complement receptor mediated signaling pathway(GO:0002430) GPI anchor release(GO:0006507)
0.1 1.0 GO:0071420 cellular response to histamine(GO:0071420)
0.1 3.3 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1 1.2 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.1 0.6 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 0.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 1.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.2 GO:0042713 sperm ejaculation(GO:0042713) negative regulation of gastric acid secretion(GO:0060455)
0.1 1.0 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 1.4 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.1 0.2 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.4 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.0 1.7 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.7 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.4 GO:0006020 inositol metabolic process(GO:0006020)
0.0 1.0 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 3.3 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.2 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.3 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 1.5 GO:0035904 aorta development(GO:0035904)
0.0 0.6 GO:0007608 sensory perception of smell(GO:0007608)
0.0 1.6 GO:0051453 regulation of intracellular pH(GO:0051453)
0.0 0.1 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.4 GO:0048670 regulation of collateral sprouting(GO:0048670)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.6 GO:0072534 perineuronal net(GO:0072534)
0.5 5.6 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.3 1.1 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.3 2.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 0.7 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.2 3.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 1.4 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 8.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 2.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 1.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 1.0 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.0 1.6 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 1.0 GO:0016324 apical plasma membrane(GO:0016324)
0.0 2.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 2.6 GO:0005657 replication fork(GO:0005657)
0.0 0.3 GO:0001739 sex chromatin(GO:0001739)
0.0 0.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.2 GO:0061574 ASAP complex(GO:0061574)
0.0 2.6 GO:0042641 actomyosin(GO:0042641)
0.0 1.4 GO:0031225 anchored component of membrane(GO:0031225)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 8.6 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
1.9 5.6 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.5 3.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.3 5.6 GO:0046625 sphingolipid binding(GO:0046625)
0.3 1.0 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.3 1.0 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.2 0.7 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.2 2.6 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.2 2.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.2 0.5 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.2 2.5 GO:0002162 dystroglycan binding(GO:0002162)
0.2 1.0 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.2 0.8 GO:0004954 icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)
0.1 1.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 1.0 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.4 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.1 0.6 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 0.7 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 1.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.6 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 2.6 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 1.0 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.4 GO:0004630 phospholipase D activity(GO:0004630)
0.0 1.1 GO:0043422 protein kinase B binding(GO:0043422)
0.0 2.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.3 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 3.3 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.3 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 1.0 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 3.9 GO:0004386 helicase activity(GO:0004386)
0.0 0.2 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 2.1 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 2.8 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.5 GO:0016831 carboxy-lyase activity(GO:0016831)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.1 PID_FOXO_PATHWAY FoxO family signaling
0.1 2.9 PID_ATR_PATHWAY ATR signaling pathway
0.1 3.5 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 1.9 PID_IL3_PATHWAY IL3-mediated signaling events
0.0 6.1 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.0 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 3.3 PID_CDC42_PATHWAY CDC42 signaling events
0.0 0.7 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.0 1.0 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.7 PID_IFNG_PATHWAY IFN-gamma pathway
0.0 0.4 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.9 PID_LKB1_PATHWAY LKB1 signaling events
0.0 1.0 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.2 5.6 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 1.0 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.1 0.5 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.2 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 1.0 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.9 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.3 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.7 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 1.0 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.6 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 2.5 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases