Motif ID: E2f1
Z-value: 6.258

Transcription factors associated with E2f1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
E2f1 | ENSMUSG00000027490.11 | E2f1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
E2f1 | mm10_v2_chr2_-_154569720_154569799 | 0.85 | 1.7e-12 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
19.2 | 57.5 | GO:0061075 | cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871) |
18.2 | 36.4 | GO:0072180 | mesonephric duct development(GO:0072177) mesonephric duct morphogenesis(GO:0072180) |
17.0 | 68.0 | GO:2000048 | negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048) |
14.6 | 43.7 | GO:0032877 | positive regulation of DNA endoreduplication(GO:0032877) |
14.5 | 43.4 | GO:0014826 | vein smooth muscle contraction(GO:0014826) |
13.7 | 163.8 | GO:0060272 | embryonic skeletal joint morphogenesis(GO:0060272) |
11.7 | 81.8 | GO:0009449 | gamma-aminobutyric acid biosynthetic process(GO:0009449) |
10.0 | 29.9 | GO:0061144 | alveolar secondary septum development(GO:0061144) |
9.0 | 45.0 | GO:2001032 | regulation of double-strand break repair via nonhomologous end joining(GO:2001032) |
8.4 | 25.3 | GO:0097402 | neuroblast migration(GO:0097402) |
8.0 | 40.1 | GO:1901165 | positive regulation of trophoblast cell migration(GO:1901165) |
8.0 | 40.0 | GO:1903553 | positive regulation of extracellular exosome assembly(GO:1903553) |
7.9 | 15.7 | GO:0044837 | assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837) |
7.7 | 30.6 | GO:0007354 | zygotic determination of anterior/posterior axis, embryo(GO:0007354) |
6.8 | 20.3 | GO:1901079 | positive regulation of relaxation of muscle(GO:1901079) |
6.5 | 19.5 | GO:1901420 | negative regulation of response to alcohol(GO:1901420) |
6.5 | 19.4 | GO:1904975 | response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976) |
6.4 | 19.3 | GO:1904395 | positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) |
6.3 | 25.3 | GO:0010986 | positive regulation of lipoprotein particle clearance(GO:0010986) |
6.1 | 12.2 | GO:0033864 | positive regulation of NAD(P)H oxidase activity(GO:0033864) |
6.0 | 90.4 | GO:0010216 | maintenance of DNA methylation(GO:0010216) |
5.9 | 29.6 | GO:0032298 | positive regulation of DNA-dependent DNA replication initiation(GO:0032298) |
5.9 | 5.9 | GO:0060423 | foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) |
5.9 | 58.6 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
5.8 | 28.8 | GO:0007089 | traversing start control point of mitotic cell cycle(GO:0007089) |
5.7 | 39.7 | GO:0098535 | de novo centriole assembly(GO:0098535) |
5.4 | 16.1 | GO:0070315 | G1 to G0 transition involved in cell differentiation(GO:0070315) |
5.3 | 21.2 | GO:0070829 | heterochromatin maintenance(GO:0070829) |
5.3 | 21.0 | GO:0006269 | DNA replication, synthesis of RNA primer(GO:0006269) |
5.2 | 109.8 | GO:0007530 | sex determination(GO:0007530) |
5.1 | 15.4 | GO:0006189 | 'de novo' IMP biosynthetic process(GO:0006189) |
5.1 | 25.3 | GO:0046654 | tetrahydrofolate biosynthetic process(GO:0046654) |
5.0 | 15.0 | GO:0030200 | heparan sulfate proteoglycan catabolic process(GO:0030200) |
5.0 | 10.0 | GO:0060718 | chorionic trophoblast cell differentiation(GO:0060718) |
5.0 | 94.3 | GO:0045653 | negative regulation of megakaryocyte differentiation(GO:0045653) |
5.0 | 34.7 | GO:1904177 | regulation of adipose tissue development(GO:1904177) |
4.9 | 14.8 | GO:0030916 | otic vesicle formation(GO:0030916) |
4.9 | 24.7 | GO:0015705 | iodide transport(GO:0015705) |
4.8 | 24.2 | GO:0045578 | negative regulation of B cell differentiation(GO:0045578) |
4.8 | 33.9 | GO:0033567 | DNA replication, Okazaki fragment processing(GO:0033567) |
4.8 | 120.1 | GO:0006270 | DNA replication initiation(GO:0006270) |
4.6 | 13.9 | GO:0045950 | negative regulation of mitotic recombination(GO:0045950) |
4.4 | 17.6 | GO:0051311 | spindle assembly involved in female meiosis(GO:0007056) meiotic metaphase plate congression(GO:0051311) |
4.4 | 17.5 | GO:0030091 | protein repair(GO:0030091) |
4.3 | 13.0 | GO:0006166 | purine ribonucleoside salvage(GO:0006166) |
4.3 | 12.9 | GO:0060598 | dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598) |
4.0 | 12.0 | GO:0021759 | globus pallidus development(GO:0021759) |
4.0 | 35.7 | GO:1900262 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
3.9 | 7.8 | GO:2000138 | positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138) |
3.8 | 15.3 | GO:0070318 | positive regulation of G0 to G1 transition(GO:0070318) |
3.8 | 19.1 | GO:0051365 | cellular response to potassium ion starvation(GO:0051365) |
3.8 | 11.4 | GO:0045409 | negative regulation of interleukin-6 biosynthetic process(GO:0045409) |
3.8 | 22.8 | GO:0033504 | floor plate development(GO:0033504) |
3.8 | 19.0 | GO:0031580 | membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) |
3.7 | 29.6 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
3.7 | 11.0 | GO:0070634 | transepithelial ammonium transport(GO:0070634) |
3.6 | 10.7 | GO:2000313 | fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314) |
3.5 | 63.6 | GO:0009263 | deoxyribonucleotide biosynthetic process(GO:0009263) |
3.5 | 7.0 | GO:0045014 | carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) |
3.4 | 6.9 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
3.4 | 24.1 | GO:0046060 | dATP metabolic process(GO:0046060) |
3.3 | 26.8 | GO:1904627 | response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628) |
3.3 | 13.3 | GO:0003360 | brainstem development(GO:0003360) |
3.3 | 9.9 | GO:0042732 | D-xylose metabolic process(GO:0042732) |
3.3 | 9.9 | GO:1904020 | regulation of G-protein coupled receptor internalization(GO:1904020) |
3.3 | 3.3 | GO:0072069 | DCT cell differentiation(GO:0072069) metanephric DCT cell differentiation(GO:0072240) |
3.3 | 6.5 | GO:0023016 | signal transduction by trans-phosphorylation(GO:0023016) |
3.2 | 3.2 | GO:0046101 | purine nucleobase biosynthetic process(GO:0009113) hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101) |
3.2 | 6.5 | GO:0009162 | deoxyribonucleoside monophosphate metabolic process(GO:0009162) |
3.1 | 9.2 | GO:0032474 | otolith morphogenesis(GO:0032474) |
3.0 | 9.0 | GO:0072139 | glomerular parietal epithelial cell differentiation(GO:0072139) |
3.0 | 17.9 | GO:0060754 | positive regulation of mast cell chemotaxis(GO:0060754) |
3.0 | 44.6 | GO:0007076 | mitotic chromosome condensation(GO:0007076) |
3.0 | 11.8 | GO:0061304 | retinal blood vessel morphogenesis(GO:0061304) |
2.9 | 14.7 | GO:0018242 | protein O-linked glycosylation via serine(GO:0018242) |
2.9 | 34.9 | GO:0060501 | positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) |
2.9 | 8.6 | GO:0006931 | substrate-dependent cell migration, cell attachment to substrate(GO:0006931) calcium-independent cell-matrix adhesion(GO:0007161) transforming growth factor-beta secretion(GO:0038044) |
2.8 | 19.8 | GO:0010273 | detoxification of copper ion(GO:0010273) cellular response to zinc ion(GO:0071294) stress response to copper ion(GO:1990169) |
2.8 | 8.3 | GO:0031660 | regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) |
2.8 | 8.3 | GO:0045004 | DNA replication proofreading(GO:0045004) |
2.6 | 7.8 | GO:0019343 | cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344) |
2.6 | 15.6 | GO:0006348 | chromatin silencing at telomere(GO:0006348) |
2.6 | 15.4 | GO:0021938 | smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938) |
2.5 | 17.6 | GO:0061087 | positive regulation of histone H3-K27 methylation(GO:0061087) |
2.4 | 29.2 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
2.4 | 7.2 | GO:0007341 | penetration of zona pellucida(GO:0007341) |
2.4 | 21.6 | GO:0001675 | acrosome assembly(GO:0001675) |
2.4 | 19.2 | GO:0090267 | positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) |
2.4 | 9.6 | GO:0046112 | nucleobase biosynthetic process(GO:0046112) |
2.4 | 7.1 | GO:0072757 | cellular response to camptothecin(GO:0072757) |
2.3 | 11.7 | GO:0021905 | pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937) |
2.3 | 7.0 | GO:0002432 | granuloma formation(GO:0002432) |
2.3 | 9.3 | GO:0044861 | protein transport into plasma membrane raft(GO:0044861) |
2.3 | 11.6 | GO:1904936 | cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936) |
2.3 | 9.2 | GO:0046604 | positive regulation of mitotic centrosome separation(GO:0046604) |
2.3 | 25.1 | GO:2000653 | regulation of genetic imprinting(GO:2000653) |
2.3 | 11.3 | GO:0000707 | meiotic DNA recombinase assembly(GO:0000707) |
2.3 | 47.4 | GO:0040034 | regulation of development, heterochronic(GO:0040034) |
2.2 | 6.6 | GO:0002184 | cytoplasmic translational termination(GO:0002184) |
2.2 | 8.8 | GO:0060265 | positive regulation of respiratory burst involved in inflammatory response(GO:0060265) |
2.2 | 6.5 | GO:0003221 | right ventricular cardiac muscle tissue morphogenesis(GO:0003221) |
2.1 | 6.3 | GO:2000418 | positive regulation of eosinophil migration(GO:2000418) |
2.1 | 6.3 | GO:0001978 | regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) |
2.1 | 6.2 | GO:1902498 | regulation of protein autoubiquitination(GO:1902498) |
2.1 | 6.2 | GO:0086053 | AV node cell to bundle of His cell communication by electrical coupling(GO:0086053) |
2.1 | 12.4 | GO:0046602 | regulation of mitotic centrosome separation(GO:0046602) |
2.0 | 14.3 | GO:0051660 | establishment of centrosome localization(GO:0051660) |
2.0 | 16.2 | GO:0033631 | cell-cell adhesion mediated by integrin(GO:0033631) |
2.0 | 2.0 | GO:0030997 | regulation of centriole-centriole cohesion(GO:0030997) |
2.0 | 7.9 | GO:0035606 | peptidyl-cysteine S-trans-nitrosylation(GO:0035606) |
2.0 | 9.8 | GO:0044806 | G-quadruplex DNA unwinding(GO:0044806) |
1.9 | 7.7 | GO:0072675 | osteoclast fusion(GO:0072675) |
1.9 | 5.8 | GO:0060672 | epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672) |
1.9 | 7.7 | GO:2001245 | regulation of phosphatidylcholine biosynthetic process(GO:2001245) |
1.9 | 1.9 | GO:0035990 | tendon cell differentiation(GO:0035990) tendon formation(GO:0035992) |
1.9 | 1.9 | GO:0045716 | low-density lipoprotein particle receptor biosynthetic process(GO:0045713) regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714) positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716) |
1.9 | 3.7 | GO:1900041 | negative regulation of interleukin-2 secretion(GO:1900041) |
1.8 | 20.1 | GO:0042473 | outer ear morphogenesis(GO:0042473) |
1.8 | 3.6 | GO:0003100 | regulation of systemic arterial blood pressure by endothelin(GO:0003100) response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) |
1.8 | 12.5 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
1.8 | 12.4 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
1.8 | 5.3 | GO:0060447 | bud outgrowth involved in lung branching(GO:0060447) |
1.7 | 31.3 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
1.7 | 5.2 | GO:0051316 | attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation(GO:0051316) |
1.7 | 16.6 | GO:0036123 | histone H3-K9 dimethylation(GO:0036123) |
1.6 | 17.9 | GO:0033260 | nuclear DNA replication(GO:0033260) |
1.6 | 12.8 | GO:0006004 | fucose metabolic process(GO:0006004) |
1.6 | 20.8 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
1.6 | 4.7 | GO:1904046 | negative regulation of vascular endothelial growth factor production(GO:1904046) |
1.6 | 7.8 | GO:0018002 | N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920) |
1.6 | 12.5 | GO:0070940 | dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940) |
1.6 | 7.8 | GO:2000348 | regulation of CD40 signaling pathway(GO:2000348) |
1.5 | 1.5 | GO:2000047 | regulation of cell-cell adhesion mediated by cadherin(GO:2000047) |
1.5 | 3.0 | GO:0061086 | negative regulation of histone H3-K27 methylation(GO:0061086) |
1.5 | 7.6 | GO:0031860 | telomeric 3' overhang formation(GO:0031860) |
1.5 | 4.5 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
1.5 | 4.5 | GO:0097350 | neutrophil clearance(GO:0097350) |
1.5 | 4.5 | GO:0033566 | gamma-tubulin complex localization(GO:0033566) |
1.5 | 1.5 | GO:1903294 | regulation of glutamate secretion, neurotransmission(GO:1903294) positive regulation of glutamate secretion, neurotransmission(GO:1903296) |
1.5 | 2.9 | GO:0006273 | lagging strand elongation(GO:0006273) |
1.5 | 2.9 | GO:0051295 | establishment of meiotic spindle localization(GO:0051295) |
1.4 | 4.3 | GO:0019441 | tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218) kynurenine metabolic process(GO:0070189) |
1.4 | 5.7 | GO:0070213 | protein auto-ADP-ribosylation(GO:0070213) |
1.4 | 4.3 | GO:1904154 | protein localization to endoplasmic reticulum exit site(GO:0070973) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154) |
1.4 | 1.4 | GO:1905066 | regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of heart induction(GO:1901321) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) |
1.4 | 8.3 | GO:0034080 | CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
1.4 | 4.1 | GO:0070889 | platelet alpha granule organization(GO:0070889) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) |
1.4 | 8.2 | GO:0090005 | negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005) |
1.4 | 4.1 | GO:0044208 | 'de novo' AMP biosynthetic process(GO:0044208) |
1.4 | 16.2 | GO:0010457 | centriole-centriole cohesion(GO:0010457) |
1.3 | 8.0 | GO:0044351 | cleavage furrow formation(GO:0036089) macropinocytosis(GO:0044351) |
1.3 | 18.3 | GO:0032098 | regulation of appetite(GO:0032098) |
1.3 | 10.3 | GO:0033327 | Leydig cell differentiation(GO:0033327) |
1.3 | 10.2 | GO:0043922 | negative regulation by host of viral transcription(GO:0043922) |
1.3 | 3.8 | GO:0071707 | immunoglobulin heavy chain V-D-J recombination(GO:0071707) |
1.3 | 6.3 | GO:0060161 | positive regulation of dopamine receptor signaling pathway(GO:0060161) |
1.3 | 17.5 | GO:0033008 | positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306) |
1.2 | 3.7 | GO:2000620 | positive regulation of histone H4-K16 acetylation(GO:2000620) |
1.2 | 24.9 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
1.2 | 5.0 | GO:0006297 | nucleotide-excision repair, DNA gap filling(GO:0006297) |
1.2 | 4.9 | GO:0000379 | tRNA-type intron splice site recognition and cleavage(GO:0000379) |
1.2 | 8.6 | GO:0000056 | ribosomal small subunit export from nucleus(GO:0000056) |
1.2 | 10.9 | GO:0045048 | protein insertion into ER membrane(GO:0045048) |
1.2 | 6.0 | GO:0046826 | negative regulation of protein export from nucleus(GO:0046826) |
1.2 | 2.4 | GO:1902869 | regulation of amacrine cell differentiation(GO:1902869) |
1.2 | 3.6 | GO:0002408 | myeloid dendritic cell chemotaxis(GO:0002408) |
1.2 | 57.9 | GO:0035019 | somatic stem cell population maintenance(GO:0035019) |
1.2 | 14.1 | GO:0043011 | myeloid dendritic cell differentiation(GO:0043011) |
1.1 | 4.6 | GO:0009414 | response to water deprivation(GO:0009414) |
1.1 | 52.7 | GO:0051310 | metaphase plate congression(GO:0051310) |
1.1 | 5.7 | GO:0002318 | myeloid progenitor cell differentiation(GO:0002318) |
1.1 | 4.6 | GO:2000319 | negative regulation of T-helper 17 type immune response(GO:2000317) regulation of T-helper 17 cell differentiation(GO:2000319) negative regulation of T-helper 17 cell differentiation(GO:2000320) |
1.1 | 5.6 | GO:0048133 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
1.1 | 26.0 | GO:0045662 | negative regulation of myoblast differentiation(GO:0045662) |
1.1 | 9.0 | GO:0046051 | UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051) |
1.1 | 7.8 | GO:0010764 | negative regulation of fibroblast migration(GO:0010764) |
1.1 | 2.2 | GO:0071603 | endothelial cell-cell adhesion(GO:0071603) |
1.1 | 5.5 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
1.1 | 4.4 | GO:0060830 | ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) |
1.1 | 1.1 | GO:0006434 | seryl-tRNA aminoacylation(GO:0006434) |
1.1 | 3.3 | GO:0042275 | error-free postreplication DNA repair(GO:0042275) |
1.1 | 2.2 | GO:0000350 | generation of catalytic spliceosome for second transesterification step(GO:0000350) |
1.1 | 3.2 | GO:0001787 | natural killer cell proliferation(GO:0001787) |
1.0 | 3.1 | GO:1902512 | positive regulation of apoptotic DNA fragmentation(GO:1902512) |
1.0 | 5.1 | GO:1903527 | regulation of membrane tubulation(GO:1903525) positive regulation of membrane tubulation(GO:1903527) |
1.0 | 13.3 | GO:0019985 | translesion synthesis(GO:0019985) |
1.0 | 6.1 | GO:0016584 | nucleosome positioning(GO:0016584) |
1.0 | 28.6 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
1.0 | 1.0 | GO:1903416 | response to glycoside(GO:1903416) |
1.0 | 2.0 | GO:0070459 | prolactin secretion(GO:0070459) |
1.0 | 5.0 | GO:0072697 | protein localization to cell cortex(GO:0072697) |
1.0 | 8.0 | GO:0031936 | negative regulation of chromatin silencing(GO:0031936) |
1.0 | 8.0 | GO:0060430 | lung saccule development(GO:0060430) |
1.0 | 1.0 | GO:1902455 | negative regulation of stem cell population maintenance(GO:1902455) |
1.0 | 10.9 | GO:0031935 | regulation of chromatin silencing(GO:0031935) |
1.0 | 10.9 | GO:0030903 | notochord development(GO:0030903) |
1.0 | 7.7 | GO:0048537 | mucosal-associated lymphoid tissue development(GO:0048537) Peyer's patch development(GO:0048541) |
1.0 | 6.7 | GO:0019336 | phenol-containing compound catabolic process(GO:0019336) |
1.0 | 8.6 | GO:0043568 | positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568) |
0.9 | 3.8 | GO:1903300 | negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300) |
0.9 | 14.2 | GO:0030261 | chromosome condensation(GO:0030261) |
0.9 | 15.8 | GO:0034508 | centromere complex assembly(GO:0034508) |
0.9 | 11.2 | GO:0036297 | interstrand cross-link repair(GO:0036297) |
0.9 | 9.2 | GO:0035520 | monoubiquitinated protein deubiquitination(GO:0035520) |
0.9 | 2.7 | GO:0015772 | disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772) |
0.9 | 7.2 | GO:0051571 | positive regulation of histone H3-K4 methylation(GO:0051571) |
0.9 | 25.2 | GO:0003416 | endochondral bone growth(GO:0003416) |
0.9 | 2.7 | GO:0048496 | maintenance of organ identity(GO:0048496) |
0.9 | 11.6 | GO:2001212 | regulation of vasculogenesis(GO:2001212) |
0.9 | 3.5 | GO:1902410 | mitotic cytokinetic process(GO:1902410) |
0.9 | 5.2 | GO:0015842 | aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) |
0.9 | 1.7 | GO:0032776 | DNA methylation on cytosine within a CG sequence(GO:0010424) DNA methylation on cytosine(GO:0032776) |
0.9 | 5.2 | GO:0097421 | liver regeneration(GO:0097421) |
0.9 | 2.6 | GO:0051026 | chiasma assembly(GO:0051026) |
0.9 | 13.7 | GO:0034389 | lipid particle organization(GO:0034389) |
0.9 | 14.5 | GO:0050434 | positive regulation of viral transcription(GO:0050434) |
0.9 | 1.7 | GO:0097360 | chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382) |
0.8 | 20.4 | GO:0046325 | negative regulation of glucose import(GO:0046325) |
0.8 | 2.5 | GO:0009446 | putrescine biosynthetic process(GO:0009446) |
0.8 | 8.3 | GO:0016127 | cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127) |
0.8 | 2.4 | GO:0010957 | negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137) Notch signaling involved in heart development(GO:0061314) |
0.8 | 2.3 | GO:0061743 | motor learning(GO:0061743) |
0.8 | 1.6 | GO:0009814 | defense response, incompatible interaction(GO:0009814) |
0.8 | 3.9 | GO:0035878 | nail development(GO:0035878) |
0.8 | 1.6 | GO:0070365 | hepatocyte differentiation(GO:0070365) |
0.8 | 3.1 | GO:0001887 | selenium compound metabolic process(GO:0001887) selenocysteine metabolic process(GO:0016259) |
0.8 | 2.3 | GO:1903334 | positive regulation of protein folding(GO:1903334) |
0.8 | 3.0 | GO:0090209 | negative regulation of triglyceride metabolic process(GO:0090209) |
0.8 | 8.3 | GO:0006353 | DNA-templated transcription, termination(GO:0006353) |
0.7 | 2.2 | GO:1902396 | protein localization to bicellular tight junction(GO:1902396) |
0.7 | 3.0 | GO:0002667 | lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) |
0.7 | 3.7 | GO:0006543 | glutamine catabolic process(GO:0006543) |
0.7 | 12.4 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
0.7 | 25.3 | GO:0046677 | response to antibiotic(GO:0046677) |
0.7 | 2.2 | GO:0019043 | establishment of viral latency(GO:0019043) |
0.7 | 13.0 | GO:1900027 | regulation of ruffle assembly(GO:1900027) |
0.7 | 34.0 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
0.7 | 7.1 | GO:0006907 | pinocytosis(GO:0006907) |
0.7 | 8.5 | GO:0075522 | IRES-dependent viral translational initiation(GO:0075522) |
0.7 | 11.9 | GO:1904816 | positive regulation of protein localization to chromosome, telomeric region(GO:1904816) |
0.7 | 7.4 | GO:0002087 | regulation of respiratory gaseous exchange by neurological system process(GO:0002087) |
0.7 | 5.3 | GO:0001842 | neural fold formation(GO:0001842) |
0.7 | 25.4 | GO:0090307 | mitotic spindle assembly(GO:0090307) |
0.7 | 4.0 | GO:0051503 | adenine nucleotide transport(GO:0051503) |
0.6 | 1.9 | GO:0045041 | protein import into mitochondrial intermembrane space(GO:0045041) |
0.6 | 3.2 | GO:1904690 | regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690) |
0.6 | 3.8 | GO:0045198 | establishment of epithelial cell apical/basal polarity(GO:0045198) |
0.6 | 18.4 | GO:0018345 | protein palmitoylation(GO:0018345) |
0.6 | 36.0 | GO:0006342 | chromatin silencing(GO:0006342) |
0.6 | 4.3 | GO:0005981 | regulation of glycogen catabolic process(GO:0005981) |
0.6 | 2.5 | GO:0000212 | meiotic spindle organization(GO:0000212) |
0.6 | 7.3 | GO:0071157 | negative regulation of cell cycle arrest(GO:0071157) |
0.6 | 6.1 | GO:2000381 | negative regulation of mesoderm development(GO:2000381) |
0.6 | 11.5 | GO:0031297 | replication fork processing(GO:0031297) |
0.6 | 3.6 | GO:1902373 | negative regulation of mRNA catabolic process(GO:1902373) |
0.6 | 8.8 | GO:0038166 | angiotensin-activated signaling pathway(GO:0038166) |
0.6 | 5.3 | GO:0006474 | N-terminal protein amino acid acetylation(GO:0006474) |
0.6 | 1.7 | GO:1901970 | positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101) |
0.6 | 1.7 | GO:0009146 | purine nucleoside triphosphate catabolic process(GO:0009146) |
0.6 | 1.7 | GO:2000383 | regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384) |
0.6 | 4.6 | GO:1902416 | positive regulation of mRNA binding(GO:1902416) |
0.6 | 1.1 | GO:0019401 | alditol biosynthetic process(GO:0019401) |
0.6 | 11.6 | GO:0044342 | type B pancreatic cell proliferation(GO:0044342) |
0.6 | 2.8 | GO:2000271 | positive regulation of fibroblast apoptotic process(GO:2000271) |
0.5 | 5.4 | GO:0021891 | olfactory bulb interneuron development(GO:0021891) |
0.5 | 2.2 | GO:2000676 | positive regulation of type B pancreatic cell apoptotic process(GO:2000676) |
0.5 | 4.3 | GO:0046599 | regulation of centriole replication(GO:0046599) |
0.5 | 4.9 | GO:0034244 | negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244) |
0.5 | 14.4 | GO:0051225 | spindle assembly(GO:0051225) |
0.5 | 15.7 | GO:0006284 | base-excision repair(GO:0006284) |
0.5 | 11.9 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
0.5 | 2.1 | GO:0046294 | formaldehyde catabolic process(GO:0046294) |
0.5 | 3.0 | GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447) |
0.5 | 10.1 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
0.5 | 10.0 | GO:0008340 | determination of adult lifespan(GO:0008340) |
0.5 | 2.5 | GO:0097503 | sialylation(GO:0097503) |
0.5 | 6.4 | GO:0039703 | viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) |
0.5 | 4.4 | GO:0032682 | negative regulation of chemokine production(GO:0032682) |
0.5 | 9.7 | GO:0052646 | alditol phosphate metabolic process(GO:0052646) |
0.5 | 5.1 | GO:0030224 | monocyte differentiation(GO:0030224) |
0.5 | 2.8 | GO:0070601 | centromeric sister chromatid cohesion(GO:0070601) |
0.4 | 4.4 | GO:0045040 | protein import into mitochondrial outer membrane(GO:0045040) |
0.4 | 4.8 | GO:0018065 | protein-cofactor linkage(GO:0018065) |
0.4 | 0.8 | GO:0010579 | regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938) |
0.4 | 2.5 | GO:0060510 | Type II pneumocyte differentiation(GO:0060510) |
0.4 | 3.8 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
0.4 | 1.2 | GO:0001828 | inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828) |
0.4 | 1.7 | GO:1902309 | negative regulation of peptidyl-serine dephosphorylation(GO:1902309) |
0.4 | 7.9 | GO:0033687 | osteoblast proliferation(GO:0033687) |
0.4 | 0.8 | GO:0060244 | negative regulation of cell proliferation involved in contact inhibition(GO:0060244) |
0.4 | 4.5 | GO:0031639 | plasminogen activation(GO:0031639) |
0.4 | 1.6 | GO:0045541 | negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206) |
0.4 | 3.2 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
0.4 | 2.4 | GO:2000270 | negative regulation of fibroblast apoptotic process(GO:2000270) |
0.4 | 5.2 | GO:0060052 | neurofilament cytoskeleton organization(GO:0060052) |
0.4 | 1.2 | GO:0060478 | acrosomal vesicle exocytosis(GO:0060478) |
0.4 | 1.2 | GO:0009298 | GDP-mannose biosynthetic process(GO:0009298) |
0.4 | 4.4 | GO:0006654 | phosphatidic acid biosynthetic process(GO:0006654) |
0.4 | 6.7 | GO:0071451 | cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) |
0.4 | 7.5 | GO:0048671 | negative regulation of collateral sprouting(GO:0048671) |
0.4 | 2.7 | GO:0097237 | cellular response to toxic substance(GO:0097237) |
0.4 | 3.5 | GO:0007440 | foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617) |
0.4 | 0.8 | GO:1902174 | positive regulation of keratinocyte apoptotic process(GO:1902174) |
0.4 | 1.2 | GO:0036353 | histone H2A-K119 monoubiquitination(GO:0036353) |
0.4 | 3.4 | GO:0043518 | negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) |
0.4 | 3.4 | GO:1905098 | negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098) |
0.4 | 3.0 | GO:0035562 | negative regulation of chromatin binding(GO:0035562) |
0.4 | 5.2 | GO:0048546 | digestive tract morphogenesis(GO:0048546) |
0.4 | 6.6 | GO:0071577 | zinc II ion transmembrane transport(GO:0071577) |
0.4 | 2.9 | GO:0006020 | inositol metabolic process(GO:0006020) |
0.4 | 8.1 | GO:0097062 | dendritic spine maintenance(GO:0097062) |
0.3 | 7.7 | GO:0043550 | regulation of lipid kinase activity(GO:0043550) |
0.3 | 4.2 | GO:0045217 | cell-cell junction maintenance(GO:0045217) |
0.3 | 1.4 | GO:0042256 | mature ribosome assembly(GO:0042256) |
0.3 | 1.7 | GO:0045721 | negative regulation of gluconeogenesis(GO:0045721) |
0.3 | 2.0 | GO:0006741 | NADP biosynthetic process(GO:0006741) |
0.3 | 1.7 | GO:1904668 | positive regulation of ubiquitin protein ligase activity(GO:1904668) |
0.3 | 5.0 | GO:0006825 | copper ion transport(GO:0006825) |
0.3 | 3.0 | GO:0007130 | synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193) |
0.3 | 1.7 | GO:0019236 | response to pheromone(GO:0019236) |
0.3 | 5.3 | GO:0002052 | positive regulation of neuroblast proliferation(GO:0002052) |
0.3 | 3.3 | GO:0000460 | maturation of 5.8S rRNA(GO:0000460) |
0.3 | 13.6 | GO:0035307 | positive regulation of protein dephosphorylation(GO:0035307) |
0.3 | 2.9 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
0.3 | 4.8 | GO:0033622 | integrin activation(GO:0033622) |
0.3 | 1.9 | GO:0031034 | myosin filament assembly(GO:0031034) |
0.3 | 13.2 | GO:0032835 | glomerulus development(GO:0032835) |
0.3 | 2.2 | GO:0006621 | protein retention in ER lumen(GO:0006621) |
0.3 | 5.0 | GO:0001709 | cell fate determination(GO:0001709) |
0.3 | 2.5 | GO:0033182 | regulation of histone ubiquitination(GO:0033182) |
0.3 | 14.7 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
0.3 | 1.2 | GO:1903286 | regulation of potassium ion import(GO:1903286) |
0.3 | 5.1 | GO:0044381 | glucose import in response to insulin stimulus(GO:0044381) |
0.3 | 44.1 | GO:0006260 | DNA replication(GO:0006260) |
0.3 | 12.8 | GO:0015914 | phospholipid transport(GO:0015914) |
0.3 | 0.3 | GO:0034140 | negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) |
0.3 | 1.1 | GO:1990928 | response to amino acid starvation(GO:1990928) |
0.3 | 1.7 | GO:0002862 | negative regulation of inflammatory response to antigenic stimulus(GO:0002862) |
0.3 | 9.3 | GO:2000134 | negative regulation of G1/S transition of mitotic cell cycle(GO:2000134) |
0.3 | 0.8 | GO:0048631 | regulation of skeletal muscle tissue growth(GO:0048631) |
0.3 | 1.4 | GO:0089700 | protein kinase D signaling(GO:0089700) |
0.3 | 0.5 | GO:0061739 | protein lipidation involved in autophagosome assembly(GO:0061739) |
0.3 | 1.6 | GO:1902036 | regulation of hematopoietic stem cell differentiation(GO:1902036) |
0.3 | 3.7 | GO:0051085 | chaperone mediated protein folding requiring cofactor(GO:0051085) |
0.3 | 1.1 | GO:0097527 | necroptotic signaling pathway(GO:0097527) |
0.3 | 3.9 | GO:0043248 | proteasome assembly(GO:0043248) |
0.3 | 19.3 | GO:0042472 | inner ear morphogenesis(GO:0042472) |
0.3 | 1.5 | GO:0072081 | proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081) specification of loop of Henle identity(GO:0072086) |
0.3 | 1.8 | GO:0035372 | protein localization to microtubule(GO:0035372) |
0.2 | 10.5 | GO:0097031 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
0.2 | 0.7 | GO:0098974 | postsynaptic actin cytoskeleton organization(GO:0098974) |
0.2 | 1.7 | GO:0045647 | negative regulation of erythrocyte differentiation(GO:0045647) |
0.2 | 1.2 | GO:1903232 | melanosome assembly(GO:1903232) |
0.2 | 0.7 | GO:0002903 | negative regulation of B cell apoptotic process(GO:0002903) |
0.2 | 2.3 | GO:2000251 | positive regulation of actin cytoskeleton reorganization(GO:2000251) |
0.2 | 6.9 | GO:0006783 | heme biosynthetic process(GO:0006783) |
0.2 | 18.3 | GO:0006888 | ER to Golgi vesicle-mediated transport(GO:0006888) |
0.2 | 0.9 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
0.2 | 1.1 | GO:0060768 | epithelial cell proliferation involved in prostate gland development(GO:0060767) regulation of epithelial cell proliferation involved in prostate gland development(GO:0060768) negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) |
0.2 | 6.7 | GO:0006405 | RNA export from nucleus(GO:0006405) |
0.2 | 2.3 | GO:0034982 | mitochondrial protein processing(GO:0034982) |
0.2 | 4.5 | GO:0045747 | positive regulation of Notch signaling pathway(GO:0045747) |
0.2 | 1.8 | GO:0035563 | positive regulation of chromatin binding(GO:0035563) |
0.2 | 8.1 | GO:0018279 | protein N-linked glycosylation via asparagine(GO:0018279) |
0.2 | 0.8 | GO:0060576 | intestinal epithelial cell development(GO:0060576) |
0.2 | 7.4 | GO:2001022 | positive regulation of response to DNA damage stimulus(GO:2001022) |
0.2 | 7.9 | GO:0032781 | positive regulation of ATPase activity(GO:0032781) |
0.2 | 15.6 | GO:0006413 | translational initiation(GO:0006413) |
0.2 | 3.3 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
0.2 | 1.5 | GO:0006390 | transcription from mitochondrial promoter(GO:0006390) |
0.2 | 1.9 | GO:0001819 | positive regulation of cytokine production(GO:0001819) |
0.2 | 0.6 | GO:0014835 | myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) |
0.2 | 0.6 | GO:0001676 | long-chain fatty acid metabolic process(GO:0001676) |
0.2 | 4.4 | GO:0006289 | nucleotide-excision repair(GO:0006289) |
0.2 | 0.7 | GO:1902775 | mitochondrial large ribosomal subunit assembly(GO:1902775) |
0.2 | 1.3 | GO:0048251 | elastic fiber assembly(GO:0048251) |
0.2 | 1.8 | GO:0006817 | phosphate ion transport(GO:0006817) |
0.2 | 1.6 | GO:0045794 | negative regulation of cell volume(GO:0045794) |
0.2 | 1.2 | GO:0035272 | exocrine system development(GO:0035272) |
0.2 | 2.6 | GO:0008637 | apoptotic mitochondrial changes(GO:0008637) |
0.2 | 2.4 | GO:0048714 | positive regulation of oligodendrocyte differentiation(GO:0048714) |
0.2 | 2.0 | GO:0035414 | negative regulation of catenin import into nucleus(GO:0035414) |
0.2 | 21.7 | GO:0043524 | negative regulation of neuron apoptotic process(GO:0043524) |
0.2 | 5.0 | GO:0046676 | negative regulation of insulin secretion(GO:0046676) |
0.2 | 6.7 | GO:0016925 | protein sumoylation(GO:0016925) |
0.2 | 1.2 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
0.2 | 0.6 | GO:0002553 | histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553) Golgi reassembly(GO:0090168) |
0.2 | 10.0 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
0.2 | 0.2 | GO:0071224 | cellular response to peptidoglycan(GO:0071224) |
0.2 | 3.6 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
0.1 | 1.5 | GO:0043984 | histone H4-K16 acetylation(GO:0043984) |
0.1 | 1.3 | GO:0060481 | lobar bronchus epithelium development(GO:0060481) |
0.1 | 1.0 | GO:1903301 | fructose 2,6-bisphosphate metabolic process(GO:0006003) regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301) |
0.1 | 8.6 | GO:0031497 | chromatin assembly(GO:0031497) |
0.1 | 0.3 | GO:0010835 | regulation of protein ADP-ribosylation(GO:0010835) |
0.1 | 2.4 | GO:1990126 | retrograde transport, endosome to plasma membrane(GO:1990126) |
0.1 | 1.6 | GO:0006415 | translational termination(GO:0006415) |
0.1 | 0.7 | GO:0014029 | neural crest formation(GO:0014029) |
0.1 | 2.5 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
0.1 | 4.3 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
0.1 | 0.3 | GO:0046655 | folic acid metabolic process(GO:0046655) |
0.1 | 0.1 | GO:0090135 | actin filament branching(GO:0090135) negative regulation of lamellipodium morphogenesis(GO:2000393) |
0.1 | 1.5 | GO:0014049 | positive regulation of glutamate secretion(GO:0014049) |
0.1 | 0.9 | GO:0055012 | ventricular cardiac muscle cell differentiation(GO:0055012) |
0.1 | 0.4 | GO:0051533 | positive regulation of NFAT protein import into nucleus(GO:0051533) |
0.1 | 2.8 | GO:1904894 | positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894) |
0.1 | 1.0 | GO:0018401 | peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) |
0.1 | 0.2 | GO:1901724 | positive regulation of cell proliferation involved in kidney development(GO:1901724) |
0.1 | 4.0 | GO:0016126 | sterol biosynthetic process(GO:0016126) |
0.1 | 0.7 | GO:0034227 | tRNA thio-modification(GO:0034227) |
0.1 | 1.6 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
0.1 | 0.2 | GO:0031440 | regulation of mRNA 3'-end processing(GO:0031440) |
0.1 | 0.7 | GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590) |
0.1 | 0.2 | GO:0021937 | cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937) |
0.1 | 5.0 | GO:0006367 | transcription initiation from RNA polymerase II promoter(GO:0006367) |
0.1 | 2.0 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
0.1 | 1.4 | GO:0006465 | signal peptide processing(GO:0006465) |
0.1 | 0.4 | GO:0016266 | O-glycan processing(GO:0016266) |
0.1 | 0.6 | GO:0006337 | nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986) |
0.1 | 2.1 | GO:0000154 | rRNA modification(GO:0000154) |
0.1 | 1.1 | GO:0045722 | positive regulation of gluconeogenesis(GO:0045722) |
0.1 | 6.3 | GO:0000910 | cytokinesis(GO:0000910) |
0.1 | 0.5 | GO:0045792 | negative regulation of cell size(GO:0045792) |
0.1 | 0.3 | GO:0035928 | rRNA import into mitochondrion(GO:0035928) |
0.1 | 9.0 | GO:0007519 | skeletal muscle tissue development(GO:0007519) |
0.1 | 2.0 | GO:0007588 | excretion(GO:0007588) |
0.1 | 1.0 | GO:1902043 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043) |
0.1 | 0.4 | GO:0046950 | cellular ketone body metabolic process(GO:0046950) |
0.1 | 0.7 | GO:0071539 | protein localization to centrosome(GO:0071539) |
0.1 | 3.3 | GO:0045454 | cell redox homeostasis(GO:0045454) |
0.1 | 0.2 | GO:0070301 | cellular response to hydrogen peroxide(GO:0070301) |
0.1 | 0.2 | GO:0021577 | hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) lateral motor column neuron migration(GO:0097477) |
0.1 | 0.5 | GO:0019835 | cytolysis(GO:0019835) |
0.1 | 0.4 | GO:0070127 | tRNA aminoacylation for mitochondrial protein translation(GO:0070127) |
0.1 | 0.6 | GO:0035315 | hair cell differentiation(GO:0035315) auditory receptor cell differentiation(GO:0042491) |
0.1 | 0.2 | GO:0000972 | transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972) |
0.1 | 1.5 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.1 | 0.2 | GO:0070166 | enamel mineralization(GO:0070166) |
0.1 | 0.6 | GO:0010172 | embryonic body morphogenesis(GO:0010172) |
0.1 | 0.2 | GO:0006824 | cobalt ion transport(GO:0006824) |
0.0 | 0.7 | GO:0000338 | protein deneddylation(GO:0000338) |
0.0 | 1.0 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
0.0 | 0.7 | GO:0035329 | hippo signaling(GO:0035329) |
0.0 | 1.1 | GO:0006911 | phagocytosis, engulfment(GO:0006911) |
0.0 | 0.2 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
0.0 | 0.1 | GO:0042754 | negative regulation of circadian rhythm(GO:0042754) |
0.0 | 1.1 | GO:0006099 | tricarboxylic acid cycle(GO:0006099) |
0.0 | 0.8 | GO:0060135 | maternal process involved in female pregnancy(GO:0060135) |
0.0 | 0.6 | GO:0042059 | negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185) |
0.0 | 0.9 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
0.0 | 1.3 | GO:0071774 | response to fibroblast growth factor(GO:0071774) |
0.0 | 0.9 | GO:0042775 | mitochondrial ATP synthesis coupled electron transport(GO:0042775) |
0.0 | 1.3 | GO:0006506 | GPI anchor biosynthetic process(GO:0006506) |
0.0 | 0.3 | GO:0071222 | cellular response to lipopolysaccharide(GO:0071222) |
0.0 | 0.3 | GO:0071897 | DNA biosynthetic process(GO:0071897) |
0.0 | 1.0 | GO:0043966 | histone H3 acetylation(GO:0043966) |
0.0 | 0.1 | GO:0010759 | positive regulation of macrophage chemotaxis(GO:0010759) |
0.0 | 0.6 | GO:0007492 | endoderm development(GO:0007492) |
0.0 | 2.5 | GO:0030217 | T cell differentiation(GO:0030217) |
0.0 | 1.9 | GO:0007623 | circadian rhythm(GO:0007623) |
0.0 | 0.4 | GO:0045071 | negative regulation of viral genome replication(GO:0045071) |
0.0 | 1.1 | GO:0072332 | intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332) |
0.0 | 0.3 | GO:0042632 | cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092) |
0.0 | 0.8 | GO:0000070 | mitotic sister chromatid segregation(GO:0000070) |
0.0 | 0.4 | GO:0048146 | positive regulation of fibroblast proliferation(GO:0048146) |
0.0 | 0.1 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
0.0 | 0.3 | GO:0090200 | positive regulation of release of cytochrome c from mitochondria(GO:0090200) |
0.0 | 0.6 | GO:2001237 | negative regulation of extrinsic apoptotic signaling pathway(GO:2001237) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
13.2 | 39.6 | GO:0097135 | cyclin E2-CDK2 complex(GO:0097135) |
12.6 | 151.5 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
10.4 | 31.3 | GO:0033186 | CAF-1 complex(GO:0033186) |
10.3 | 51.4 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
9.1 | 136.8 | GO:0042555 | MCM complex(GO:0042555) |
6.6 | 26.5 | GO:1990590 | ATF1-ATF4 transcription factor complex(GO:1990590) |
6.3 | 37.7 | GO:0098536 | deuterosome(GO:0098536) |
5.5 | 16.5 | GO:1990423 | RZZ complex(GO:1990423) |
5.5 | 16.5 | GO:0000801 | central element(GO:0000801) |
5.4 | 27.0 | GO:0031523 | Myb complex(GO:0031523) |
5.1 | 51.4 | GO:0000796 | condensin complex(GO:0000796) |
5.0 | 29.9 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
4.4 | 13.3 | GO:0097059 | CNTFR-CLCF1 complex(GO:0097059) |
4.3 | 26.0 | GO:0035976 | AP1 complex(GO:0035976) |
4.2 | 21.0 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
4.1 | 12.3 | GO:0071149 | TEAD-2-YAP complex(GO:0071149) |
4.0 | 12.1 | GO:0036387 | nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387) |
4.0 | 7.9 | GO:0071953 | elastic fiber(GO:0071953) |
3.5 | 7.0 | GO:0036488 | CHOP-C/EBP complex(GO:0036488) |
3.3 | 9.8 | GO:0099573 | glutamatergic postsynaptic density(GO:0099573) |
3.2 | 22.1 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
3.1 | 15.7 | GO:0097149 | centralspindlin complex(GO:0097149) |
3.1 | 100.7 | GO:0000788 | nuclear nucleosome(GO:0000788) |
3.0 | 15.2 | GO:0001740 | Barr body(GO:0001740) |
3.0 | 9.0 | GO:0071914 | prominosome(GO:0071914) |
2.9 | 8.6 | GO:0005577 | fibrinogen complex(GO:0005577) |
2.9 | 8.6 | GO:0031074 | nucleocytoplasmic shuttling complex(GO:0031074) |
2.8 | 11.3 | GO:0000942 | condensed nuclear chromosome outer kinetochore(GO:0000942) |
2.8 | 8.3 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
2.6 | 5.2 | GO:0000939 | condensed chromosome inner kinetochore(GO:0000939) |
2.5 | 15.1 | GO:0005664 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
2.4 | 12.2 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
2.3 | 2.3 | GO:0044301 | climbing fiber(GO:0044301) |
2.3 | 11.3 | GO:0033063 | Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
2.2 | 11.1 | GO:0097226 | sperm mitochondrial sheath(GO:0097226) |
2.2 | 6.6 | GO:0018444 | translation release factor complex(GO:0018444) |
2.2 | 8.7 | GO:0005606 | laminin-1 complex(GO:0005606) |
2.1 | 10.6 | GO:0031390 | Ctf18 RFC-like complex(GO:0031390) |
2.0 | 116.8 | GO:0005657 | replication fork(GO:0005657) |
2.0 | 17.6 | GO:0072687 | meiotic spindle(GO:0072687) |
1.9 | 38.9 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
1.9 | 40.1 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
1.9 | 20.6 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
1.8 | 31.3 | GO:0065010 | extracellular membrane-bounded organelle(GO:0065010) |
1.8 | 69.5 | GO:0060077 | inhibitory synapse(GO:0060077) |
1.8 | 7.2 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
1.7 | 6.9 | GO:0000931 | gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274) |
1.7 | 5.2 | GO:0031510 | SUMO activating enzyme complex(GO:0031510) |
1.7 | 13.7 | GO:0070652 | HAUS complex(GO:0070652) |
1.7 | 55.9 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
1.7 | 10.0 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
1.6 | 22.6 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
1.5 | 4.6 | GO:1990075 | stereocilia ankle link complex(GO:0002142) periciliary membrane compartment(GO:1990075) |
1.5 | 4.6 | GO:0005673 | transcription factor TFIIE complex(GO:0005673) |
1.5 | 25.1 | GO:0005652 | nuclear lamina(GO:0005652) |
1.3 | 9.3 | GO:0044352 | pinosome(GO:0044352) macropinosome(GO:0044354) |
1.3 | 6.6 | GO:0005688 | U6 snRNP(GO:0005688) |
1.3 | 10.6 | GO:0031415 | NatA complex(GO:0031415) |
1.3 | 11.5 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
1.2 | 4.9 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
1.2 | 8.5 | GO:0097422 | tubular endosome(GO:0097422) |
1.2 | 11.9 | GO:0097431 | mitotic spindle pole(GO:0097431) |
1.2 | 4.7 | GO:0008623 | CHRAC(GO:0008623) |
1.2 | 13.9 | GO:0016600 | flotillin complex(GO:0016600) |
1.1 | 5.7 | GO:0033010 | paranodal junction(GO:0033010) |
1.1 | 7.9 | GO:0097452 | GAIT complex(GO:0097452) |
1.1 | 5.6 | GO:0005828 | kinetochore microtubule(GO:0005828) |
1.1 | 4.4 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
1.1 | 24.7 | GO:0008305 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
1.1 | 4.3 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
1.0 | 5.2 | GO:0072487 | MSL complex(GO:0072487) |
1.0 | 5.1 | GO:0001652 | granular component(GO:0001652) |
1.0 | 4.0 | GO:0030289 | protein phosphatase 4 complex(GO:0030289) |
1.0 | 6.8 | GO:0030915 | Smc5-Smc6 complex(GO:0030915) |
1.0 | 9.6 | GO:0034709 | methylosome(GO:0034709) |
0.9 | 15.2 | GO:0044453 | nuclear membrane part(GO:0044453) |
0.9 | 9.1 | GO:0030057 | desmosome(GO:0030057) |
0.9 | 2.7 | GO:0097543 | ciliary inversin compartment(GO:0097543) |
0.9 | 7.9 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
0.9 | 5.2 | GO:0000938 | GARP complex(GO:0000938) |
0.9 | 4.3 | GO:0005784 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
0.8 | 5.1 | GO:0070776 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
0.8 | 5.9 | GO:0097165 | nuclear stress granule(GO:0097165) |
0.8 | 40.1 | GO:0031519 | PcG protein complex(GO:0031519) |
0.8 | 5.0 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
0.8 | 4.9 | GO:0000214 | tRNA-intron endonuclease complex(GO:0000214) |
0.8 | 2.5 | GO:0031372 | UBC13-MMS2 complex(GO:0031372) |
0.8 | 3.2 | GO:0002189 | ribose phosphate diphosphokinase complex(GO:0002189) |
0.8 | 6.4 | GO:0071598 | neuronal ribonucleoprotein granule(GO:0071598) |
0.8 | 22.2 | GO:0051233 | spindle midzone(GO:0051233) |
0.7 | 8.2 | GO:0097542 | ciliary tip(GO:0097542) |
0.7 | 9.6 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
0.7 | 11.0 | GO:1904115 | axon cytoplasm(GO:1904115) |
0.7 | 67.9 | GO:0005814 | centriole(GO:0005814) |
0.6 | 35.1 | GO:0005882 | intermediate filament(GO:0005882) |
0.6 | 4.5 | GO:0002177 | manchette(GO:0002177) |
0.6 | 3.7 | GO:0070531 | BRCA1-A complex(GO:0070531) |
0.6 | 4.3 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
0.6 | 6.8 | GO:0016442 | RISC complex(GO:0016442) RNAi effector complex(GO:0031332) |
0.6 | 21.1 | GO:0034707 | chloride channel complex(GO:0034707) |
0.6 | 4.1 | GO:0031371 | ubiquitin conjugating enzyme complex(GO:0031371) |
0.6 | 2.3 | GO:0005745 | m-AAA complex(GO:0005745) |
0.6 | 2.3 | GO:0032021 | NELF complex(GO:0032021) |
0.6 | 9.2 | GO:0030008 | TRAPP complex(GO:0030008) |
0.6 | 1.1 | GO:0090571 | RNA polymerase II transcription repressor complex(GO:0090571) |
0.5 | 7.9 | GO:0045120 | pronucleus(GO:0045120) |
0.5 | 26.7 | GO:0009925 | basal plasma membrane(GO:0009925) |
0.5 | 2.6 | GO:0071204 | histone pre-mRNA 3'end processing complex(GO:0071204) |
0.5 | 1.0 | GO:0031931 | TORC1 complex(GO:0031931) |
0.5 | 5.6 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
0.5 | 5.1 | GO:0097526 | U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526) |
0.5 | 4.4 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
0.5 | 2.5 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
0.5 | 34.6 | GO:0005844 | polysome(GO:0005844) |
0.5 | 3.4 | GO:0036195 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
0.5 | 10.9 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
0.5 | 20.8 | GO:0043034 | costamere(GO:0043034) |
0.5 | 76.2 | GO:0000775 | chromosome, centromeric region(GO:0000775) |
0.4 | 21.4 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
0.4 | 5.3 | GO:0044294 | dendritic growth cone(GO:0044294) |
0.4 | 3.0 | GO:0042824 | MHC class I peptide loading complex(GO:0042824) TAP complex(GO:0042825) |
0.4 | 2.1 | GO:0070876 | SOSS complex(GO:0070876) |
0.4 | 3.4 | GO:0005851 | eukaryotic translation initiation factor 2B complex(GO:0005851) |
0.4 | 1.7 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
0.4 | 3.8 | GO:0000974 | Prp19 complex(GO:0000974) |
0.4 | 11.1 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
0.4 | 3.3 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
0.4 | 1.2 | GO:0071008 | U2-type post-mRNA release spliceosomal complex(GO:0071008) |
0.4 | 3.2 | GO:0046581 | intercellular canaliculus(GO:0046581) |
0.4 | 14.0 | GO:0002102 | podosome(GO:0002102) |
0.4 | 4.1 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
0.4 | 22.8 | GO:0000793 | condensed chromosome(GO:0000793) |
0.4 | 2.9 | GO:0090543 | Flemming body(GO:0090543) |
0.4 | 5.1 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
0.4 | 4.7 | GO:0005640 | nuclear outer membrane(GO:0005640) |
0.4 | 8.0 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
0.4 | 30.4 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
0.3 | 1.0 | GO:0043540 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540) |
0.3 | 3.3 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
0.3 | 9.8 | GO:0035869 | ciliary transition zone(GO:0035869) |
0.3 | 1.6 | GO:0060293 | P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293) |
0.3 | 2.2 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
0.3 | 120.1 | GO:0000228 | nuclear chromosome(GO:0000228) |
0.3 | 1.2 | GO:0042827 | platelet dense granule(GO:0042827) |
0.3 | 26.5 | GO:0005681 | spliceosomal complex(GO:0005681) |
0.3 | 3.9 | GO:0005922 | connexon complex(GO:0005922) |
0.3 | 4.4 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
0.3 | 7.9 | GO:0016592 | mediator complex(GO:0016592) |
0.3 | 10.3 | GO:0055038 | recycling endosome membrane(GO:0055038) |
0.3 | 1.1 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) |
0.3 | 2.3 | GO:0045252 | dihydrolipoyl dehydrogenase complex(GO:0045240) oxoglutarate dehydrogenase complex(GO:0045252) |
0.3 | 1.6 | GO:0000125 | PCAF complex(GO:0000125) |
0.3 | 3.1 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
0.2 | 3.2 | GO:0090544 | BAF-type complex(GO:0090544) |
0.2 | 13.4 | GO:0031526 | brush border membrane(GO:0031526) |
0.2 | 3.9 | GO:0031083 | BLOC-1 complex(GO:0031083) |
0.2 | 1.9 | GO:0005787 | signal peptidase complex(GO:0005787) |
0.2 | 2.4 | GO:0045298 | tubulin complex(GO:0045298) |
0.2 | 1.4 | GO:0005859 | muscle myosin complex(GO:0005859) |
0.2 | 1.9 | GO:0000815 | ESCRT III complex(GO:0000815) |
0.2 | 16.6 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.2 | 8.8 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
0.2 | 11.4 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
0.2 | 0.7 | GO:0030690 | Noc1p-Noc2p complex(GO:0030690) |
0.2 | 39.9 | GO:0009897 | external side of plasma membrane(GO:0009897) |
0.2 | 1.1 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
0.2 | 2.9 | GO:0008540 | proteasome regulatory particle, base subcomplex(GO:0008540) |
0.2 | 1.5 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
0.2 | 7.7 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
0.2 | 1.0 | GO:0097255 | R2TP complex(GO:0097255) |
0.2 | 20.5 | GO:0043195 | terminal bouton(GO:0043195) |
0.2 | 7.3 | GO:0016235 | aggresome(GO:0016235) |
0.2 | 34.9 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
0.2 | 1.5 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
0.2 | 1.6 | GO:0061574 | ASAP complex(GO:0061574) |
0.2 | 17.0 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
0.2 | 61.8 | GO:0009986 | cell surface(GO:0009986) |
0.2 | 1.1 | GO:0097470 | ribbon synapse(GO:0097470) |
0.2 | 11.3 | GO:0000502 | proteasome complex(GO:0000502) |
0.2 | 1.5 | GO:0016272 | prefoldin complex(GO:0016272) |
0.2 | 8.7 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
0.2 | 4.8 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
0.2 | 9.9 | GO:0036064 | ciliary basal body(GO:0036064) |
0.2 | 7.0 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
0.2 | 20.2 | GO:0001650 | fibrillar center(GO:0001650) |
0.2 | 3.9 | GO:0005876 | spindle microtubule(GO:0005876) |
0.1 | 8.1 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
0.1 | 0.6 | GO:0031501 | mannosyltransferase complex(GO:0031501) |
0.1 | 1.7 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
0.1 | 4.1 | GO:0014704 | intercalated disc(GO:0014704) |
0.1 | 1.7 | GO:0030673 | axolemma(GO:0030673) |
0.1 | 7.7 | GO:0044391 | ribosomal subunit(GO:0044391) |
0.1 | 22.2 | GO:0005667 | transcription factor complex(GO:0005667) |
0.1 | 0.7 | GO:0071986 | Ragulator complex(GO:0071986) |
0.1 | 2.9 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
0.1 | 0.3 | GO:0045171 | intercellular bridge(GO:0045171) |
0.1 | 1.2 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
0.1 | 4.4 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
0.1 | 1.5 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
0.1 | 2.0 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
0.1 | 3.6 | GO:0043198 | dendritic shaft(GO:0043198) |
0.1 | 6.3 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
0.1 | 0.9 | GO:0048786 | presynaptic active zone(GO:0048786) |
0.1 | 0.9 | GO:0005797 | Golgi medial cisterna(GO:0005797) |
0.1 | 0.2 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
0.1 | 412.0 | GO:0005634 | nucleus(GO:0005634) |
0.1 | 2.0 | GO:0016459 | myosin complex(GO:0016459) |
0.0 | 0.2 | GO:0033655 | host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655) |
0.0 | 0.4 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
0.0 | 0.1 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
0.0 | 0.4 | GO:0005811 | lipid particle(GO:0005811) |
0.0 | 1.3 | GO:0043209 | myelin sheath(GO:0043209) |
0.0 | 0.2 | GO:0005832 | zona pellucida receptor complex(GO:0002199) chaperonin-containing T-complex(GO:0005832) |
0.0 | 5.7 | GO:0048471 | perinuclear region of cytoplasm(GO:0048471) |
0.0 | 1.9 | GO:0005759 | mitochondrial matrix(GO:0005759) |
0.0 | 0.3 | GO:0030126 | COPI vesicle coat(GO:0030126) |
0.0 | 1.6 | GO:0005923 | bicellular tight junction(GO:0005923) |
0.0 | 0.3 | GO:0005614 | interstitial matrix(GO:0005614) |
0.0 | 1.9 | GO:0043235 | receptor complex(GO:0043235) |
0.0 | 0.1 | GO:0061617 | MICOS complex(GO:0061617) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
30.4 | 151.9 | GO:0042289 | MHC class II protein binding(GO:0042289) |
18.6 | 74.4 | GO:0044729 | hemi-methylated DNA-binding(GO:0044729) |
15.0 | 60.0 | GO:0008970 | phosphatidylcholine 1-acylhydrolase activity(GO:0008970) |
13.7 | 41.0 | GO:0004962 | endothelin receptor activity(GO:0004962) |
11.3 | 79.4 | GO:0004351 | glutamate decarboxylase activity(GO:0004351) |
10.3 | 51.4 | GO:0061731 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
8.7 | 26.2 | GO:0004731 | purine-nucleoside phosphorylase activity(GO:0004731) |
7.7 | 30.8 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
7.2 | 7.2 | GO:0015616 | DNA translocase activity(GO:0015616) |
6.2 | 24.7 | GO:0015111 | iodide transmembrane transporter activity(GO:0015111) |
5.5 | 27.3 | GO:0043515 | kinetochore binding(GO:0043515) |
5.2 | 31.3 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
5.0 | 15.0 | GO:0070052 | collagen V binding(GO:0070052) |
4.3 | 25.8 | GO:0003910 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
4.2 | 37.6 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
4.1 | 12.4 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
3.8 | 15.3 | GO:0004477 | methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488) |
3.8 | 30.5 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
3.7 | 18.5 | GO:1904047 | S-adenosyl-L-methionine binding(GO:1904047) |
3.7 | 40.5 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
3.5 | 7.0 | GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity(GO:0051575) |
3.3 | 10.0 | GO:0051870 | methotrexate binding(GO:0051870) |
3.2 | 119.8 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
3.2 | 12.8 | GO:0042806 | fucose binding(GO:0042806) |
3.0 | 12.2 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
3.0 | 17.8 | GO:0033743 | peptide-methionine (R)-S-oxide reductase activity(GO:0033743) |
2.9 | 96.4 | GO:0070412 | R-SMAD binding(GO:0070412) |
2.9 | 46.6 | GO:0003680 | AT DNA binding(GO:0003680) |
2.6 | 7.9 | GO:0035605 | peptidyl-cysteine S-nitrosylase activity(GO:0035605) |
2.5 | 9.9 | GO:0001602 | pancreatic polypeptide receptor activity(GO:0001602) |
2.4 | 9.6 | GO:0016812 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812) |
2.4 | 16.6 | GO:0015198 | oligopeptide transporter activity(GO:0015198) |
2.4 | 19.0 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
2.4 | 28.3 | GO:0035173 | histone kinase activity(GO:0035173) |
2.3 | 25.7 | GO:0048406 | nerve growth factor binding(GO:0048406) |
2.3 | 15.8 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
2.2 | 13.3 | GO:0004897 | ciliary neurotrophic factor receptor activity(GO:0004897) |
2.2 | 11.0 | GO:0017108 | 5'-flap endonuclease activity(GO:0017108) |
2.2 | 13.1 | GO:1990189 | peptide-serine-N-acetyltransferase activity(GO:1990189) |
2.2 | 6.5 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
2.2 | 6.5 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
2.1 | 12.4 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
2.1 | 6.2 | GO:0086077 | gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077) |
2.0 | 6.1 | GO:0071207 | histone pre-mRNA stem-loop binding(GO:0071207) |
2.0 | 18.0 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
2.0 | 8.0 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
1.9 | 7.8 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
1.9 | 9.6 | GO:0047134 | protein-disulfide reductase activity(GO:0047134) |
1.9 | 100.2 | GO:0003678 | DNA helicase activity(GO:0003678) |
1.8 | 7.2 | GO:0005113 | patched binding(GO:0005113) |
1.6 | 4.9 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
1.6 | 11.3 | GO:0000150 | recombinase activity(GO:0000150) |
1.6 | 23.8 | GO:0032552 | deoxyribonucleotide binding(GO:0032552) |
1.6 | 12.7 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
1.5 | 12.2 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
1.5 | 6.1 | GO:0016971 | flavin-linked sulfhydryl oxidase activity(GO:0016971) |
1.5 | 6.1 | GO:0008821 | crossover junction endodeoxyribonuclease activity(GO:0008821) |
1.5 | 30.1 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
1.5 | 28.2 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
1.5 | 16.2 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
1.5 | 5.8 | GO:0004720 | protein-lysine 6-oxidase activity(GO:0004720) |
1.4 | 8.6 | GO:0045340 | mercury ion binding(GO:0045340) |
1.4 | 8.6 | GO:0070883 | pre-miRNA binding(GO:0070883) |
1.4 | 32.4 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
1.4 | 6.8 | GO:0004322 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
1.3 | 48.4 | GO:0017025 | TBP-class protein binding(GO:0017025) |
1.3 | 4.0 | GO:0046964 | 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964) |
1.3 | 6.6 | GO:0030621 | U4 snRNA binding(GO:0030621) |
1.3 | 5.2 | GO:0036468 | aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468) |
1.3 | 1.3 | GO:0050436 | microfibril binding(GO:0050436) |
1.3 | 31.2 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
1.3 | 25.9 | GO:0001222 | transcription corepressor binding(GO:0001222) |
1.3 | 7.7 | GO:0070644 | vitamin D response element binding(GO:0070644) |
1.3 | 7.6 | GO:0008494 | translation activator activity(GO:0008494) |
1.2 | 19.9 | GO:0030957 | Tat protein binding(GO:0030957) |
1.2 | 8.5 | GO:0008296 | 3'-5'-exodeoxyribonuclease activity(GO:0008296) |
1.2 | 4.8 | GO:0071558 | histone demethylase activity (H3-K27 specific)(GO:0071558) |
1.2 | 2.4 | GO:0000405 | bubble DNA binding(GO:0000405) |
1.1 | 4.5 | GO:0019808 | polyamine binding(GO:0019808) |
1.1 | 2.3 | GO:0019966 | interleukin-1 binding(GO:0019966) |
1.1 | 11.1 | GO:0004017 | adenylate kinase activity(GO:0004017) |
1.1 | 1.1 | GO:0004828 | serine-tRNA ligase activity(GO:0004828) |
1.1 | 8.8 | GO:0003747 | translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079) |
1.1 | 6.5 | GO:0019103 | pyrimidine nucleotide binding(GO:0019103) |
1.1 | 8.7 | GO:0043208 | glycosphingolipid binding(GO:0043208) |
1.1 | 3.2 | GO:0033829 | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829) |
1.1 | 5.3 | GO:0045545 | syndecan binding(GO:0045545) |
1.1 | 11.6 | GO:0001134 | transcription factor activity, transcription factor recruiting(GO:0001134) |
1.0 | 17.8 | GO:0042056 | chemoattractant activity(GO:0042056) |
1.0 | 8.3 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
1.0 | 4.1 | GO:0016842 | amidine-lyase activity(GO:0016842) |
1.0 | 220.2 | GO:0042393 | histone binding(GO:0042393) |
1.0 | 7.1 | GO:0034452 | dynactin binding(GO:0034452) |
1.0 | 3.0 | GO:0009041 | uridylate kinase activity(GO:0009041) |
1.0 | 7.8 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
0.9 | 8.5 | GO:0050692 | DBD domain binding(GO:0050692) |
0.9 | 7.5 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
0.9 | 4.6 | GO:0003945 | N-acetyllactosamine synthase activity(GO:0003945) |
0.9 | 2.7 | GO:0008515 | sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157) |
0.9 | 18.0 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
0.9 | 9.0 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
0.9 | 9.8 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
0.9 | 7.1 | GO:0097200 | cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200) |
0.9 | 20.2 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
0.9 | 5.2 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
0.9 | 0.9 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
0.8 | 16.1 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
0.8 | 15.1 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
0.8 | 13.3 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
0.8 | 3.3 | GO:0010484 | H3 histone acetyltransferase activity(GO:0010484) |
0.8 | 3.3 | GO:1990715 | mRNA CDS binding(GO:1990715) |
0.8 | 4.9 | GO:0000213 | tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892) |
0.8 | 2.5 | GO:0016901 | glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901) |
0.8 | 3.2 | GO:0004749 | ribose phosphate diphosphokinase activity(GO:0004749) |
0.8 | 7.3 | GO:0003993 | acid phosphatase activity(GO:0003993) |
0.8 | 11.2 | GO:0008484 | sulfuric ester hydrolase activity(GO:0008484) |
0.8 | 10.3 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
0.8 | 18.0 | GO:0017160 | Ral GTPase binding(GO:0017160) |
0.8 | 3.9 | GO:0038132 | neuregulin binding(GO:0038132) |
0.8 | 3.1 | GO:0070279 | vitamin B6 binding(GO:0070279) |
0.8 | 28.3 | GO:0008536 | Ran GTPase binding(GO:0008536) |
0.7 | 14.8 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
0.7 | 5.9 | GO:0044388 | small protein activating enzyme binding(GO:0044388) |
0.7 | 4.4 | GO:0097493 | structural molecule activity conferring elasticity(GO:0097493) |
0.7 | 2.9 | GO:0003836 | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) |
0.7 | 3.6 | GO:0051022 | Rho GDP-dissociation inhibitor binding(GO:0051022) |
0.7 | 2.1 | GO:0004534 | 5'-3' exoribonuclease activity(GO:0004534) |
0.7 | 2.8 | GO:0000700 | mismatch base pair DNA N-glycosylase activity(GO:0000700) |
0.7 | 25.8 | GO:0005507 | copper ion binding(GO:0005507) |
0.7 | 2.1 | GO:0018738 | S-formylglutathione hydrolase activity(GO:0018738) |
0.7 | 8.9 | GO:1990459 | transferrin receptor binding(GO:1990459) |
0.7 | 66.5 | GO:0004386 | helicase activity(GO:0004386) |
0.7 | 2.0 | GO:0003696 | satellite DNA binding(GO:0003696) |
0.7 | 16.9 | GO:0016881 | acid-amino acid ligase activity(GO:0016881) |
0.6 | 1.9 | GO:0016894 | endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters(GO:0016894) |
0.6 | 18.4 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
0.6 | 3.7 | GO:0004852 | uroporphyrinogen-III synthase activity(GO:0004852) |
0.6 | 62.1 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
0.6 | 1.8 | GO:0005436 | sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319) |
0.6 | 4.1 | GO:0042609 | CD4 receptor binding(GO:0042609) |
0.6 | 2.9 | GO:0051425 | PTB domain binding(GO:0051425) |
0.6 | 1.7 | GO:0042895 | antibiotic transporter activity(GO:0042895) |
0.6 | 1.2 | GO:0071535 | RING-like zinc finger domain binding(GO:0071535) |
0.6 | 13.8 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
0.6 | 3.4 | GO:0016018 | cyclosporin A binding(GO:0016018) |
0.6 | 4.5 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
0.6 | 25.4 | GO:0070063 | RNA polymerase binding(GO:0070063) |
0.6 | 41.6 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
0.6 | 12.9 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
0.5 | 2.2 | GO:0046923 | ER retention sequence binding(GO:0046923) |
0.5 | 7.0 | GO:0008327 | methyl-CpG binding(GO:0008327) |
0.5 | 83.3 | GO:0001047 | core promoter binding(GO:0001047) |
0.5 | 1.1 | GO:0035877 | death effector domain binding(GO:0035877) |
0.5 | 8.9 | GO:0008519 | ammonium transmembrane transporter activity(GO:0008519) |
0.5 | 1.5 | GO:0019153 | protein-disulfide reductase (glutathione) activity(GO:0019153) |
0.5 | 5.3 | GO:0070182 | DNA polymerase binding(GO:0070182) |
0.5 | 12.0 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
0.5 | 17.3 | GO:0031490 | chromatin DNA binding(GO:0031490) |
0.5 | 1.4 | GO:0048019 | receptor antagonist activity(GO:0048019) |
0.5 | 7.4 | GO:0016799 | hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799) |
0.5 | 2.3 | GO:0035614 | snRNA stem-loop binding(GO:0035614) |
0.5 | 16.2 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
0.4 | 4.4 | GO:0015266 | protein channel activity(GO:0015266) |
0.4 | 2.2 | GO:0043237 | laminin-1 binding(GO:0043237) |
0.4 | 1.7 | GO:0035529 | NADH pyrophosphatase activity(GO:0035529) |
0.4 | 6.5 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
0.4 | 5.1 | GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
0.4 | 8.0 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
0.4 | 3.9 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
0.4 | 6.3 | GO:0031748 | D1 dopamine receptor binding(GO:0031748) |
0.4 | 9.9 | GO:0031369 | translation initiation factor binding(GO:0031369) |
0.4 | 3.0 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
0.4 | 21.1 | GO:0003743 | translation initiation factor activity(GO:0003743) |
0.4 | 6.3 | GO:0042805 | actinin binding(GO:0042805) |
0.4 | 1.5 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
0.4 | 2.9 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
0.4 | 8.3 | GO:0043274 | phospholipase binding(GO:0043274) |
0.4 | 5.7 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
0.3 | 0.7 | GO:0046978 | TAP1 binding(GO:0046978) TAP2 binding(GO:0046979) |
0.3 | 4.3 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
0.3 | 4.3 | GO:0031418 | L-ascorbic acid binding(GO:0031418) |
0.3 | 2.3 | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) |
0.3 | 1.0 | GO:0004045 | aminoacyl-tRNA hydrolase activity(GO:0004045) |
0.3 | 20.7 | GO:0005080 | protein kinase C binding(GO:0005080) |
0.3 | 6.4 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
0.3 | 2.9 | GO:0008556 | sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556) |
0.3 | 1.6 | GO:1990188 | euchromatin binding(GO:1990188) |
0.3 | 2.5 | GO:0000400 | four-way junction DNA binding(GO:0000400) |
0.3 | 8.9 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
0.3 | 3.8 | GO:0015035 | protein disulfide oxidoreductase activity(GO:0015035) |
0.3 | 11.4 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.3 | 8.5 | GO:0008307 | structural constituent of muscle(GO:0008307) |
0.3 | 4.9 | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) |
0.3 | 10.9 | GO:0019200 | carbohydrate kinase activity(GO:0019200) |
0.3 | 1.1 | GO:0008967 | phosphoglycolate phosphatase activity(GO:0008967) |
0.3 | 3.9 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
0.3 | 6.8 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.2 | 11.5 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650) |
0.2 | 5.5 | GO:0016763 | transferase activity, transferring pentosyl groups(GO:0016763) |
0.2 | 1.7 | GO:0050815 | phosphoserine binding(GO:0050815) |
0.2 | 4.5 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
0.2 | 3.5 | GO:1990381 | ubiquitin-specific protease binding(GO:1990381) |
0.2 | 11.9 | GO:0002039 | p53 binding(GO:0002039) |
0.2 | 3.0 | GO:0070034 | telomerase RNA binding(GO:0070034) |
0.2 | 9.0 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
0.2 | 4.3 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
0.2 | 5.4 | GO:0050840 | extracellular matrix binding(GO:0050840) |
0.2 | 6.2 | GO:0005109 | frizzled binding(GO:0005109) |
0.2 | 0.6 | GO:0047179 | platelet-activating factor acetyltransferase activity(GO:0047179) |
0.2 | 4.6 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
0.2 | 2.9 | GO:0031491 | nucleosome binding(GO:0031491) |
0.2 | 2.5 | GO:0042288 | MHC class I protein binding(GO:0042288) |
0.2 | 0.8 | GO:0061665 | SUMO ligase activity(GO:0061665) |
0.2 | 0.6 | GO:0051525 | NFAT protein binding(GO:0051525) |
0.2 | 3.4 | GO:0003995 | acyl-CoA dehydrogenase activity(GO:0003995) |
0.2 | 0.7 | GO:0050632 | propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121) |
0.2 | 4.2 | GO:0016628 | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628) |
0.2 | 1.1 | GO:0097027 | ubiquitin-protein transferase activator activity(GO:0097027) |
0.2 | 0.5 | GO:0019002 | GMP binding(GO:0019002) |
0.2 | 1.1 | GO:0016618 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
0.2 | 0.9 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
0.2 | 28.7 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
0.2 | 4.8 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
0.2 | 1.7 | GO:0001530 | lipopolysaccharide binding(GO:0001530) |
0.2 | 5.1 | GO:0046332 | SMAD binding(GO:0046332) |
0.2 | 28.5 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
0.2 | 1.2 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
0.1 | 1.0 | GO:1990446 | snRNP binding(GO:0070990) U1 snRNP binding(GO:1990446) |
0.1 | 2.3 | GO:0051400 | BH domain binding(GO:0051400) |
0.1 | 1.4 | GO:0004697 | protein kinase C activity(GO:0004697) |
0.1 | 4.7 | GO:0001104 | RNA polymerase II transcription cofactor activity(GO:0001104) |
0.1 | 29.0 | GO:0003682 | chromatin binding(GO:0003682) |
0.1 | 3.6 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.1 | 7.8 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.1 | 2.0 | GO:0003951 | NAD+ kinase activity(GO:0003951) |
0.1 | 24.4 | GO:0008022 | protein C-terminus binding(GO:0008022) |
0.1 | 0.8 | GO:0000182 | rDNA binding(GO:0000182) |
0.1 | 8.3 | GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553) |
0.1 | 0.4 | GO:0016833 | oxo-acid-lyase activity(GO:0016833) |
0.1 | 1.4 | GO:0004707 | MAP kinase activity(GO:0004707) |
0.1 | 0.5 | GO:0050897 | cobalt ion binding(GO:0050897) |
0.1 | 1.5 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
0.1 | 1.2 | GO:0016868 | intramolecular transferase activity, phosphotransferases(GO:0016868) |
0.1 | 0.3 | GO:0004830 | tryptophan-tRNA ligase activity(GO:0004830) |
0.1 | 4.6 | GO:0019894 | kinesin binding(GO:0019894) |
0.1 | 2.9 | GO:0050699 | WW domain binding(GO:0050699) |
0.1 | 2.6 | GO:0031072 | heat shock protein binding(GO:0031072) |
0.1 | 1.6 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
0.1 | 5.3 | GO:0019905 | syntaxin binding(GO:0019905) |
0.1 | 4.5 | GO:0005178 | integrin binding(GO:0005178) |
0.1 | 0.3 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
0.1 | 1.6 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
0.1 | 1.3 | GO:0008373 | sialyltransferase activity(GO:0008373) |
0.1 | 8.9 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) |
0.1 | 1.2 | GO:0017091 | AU-rich element binding(GO:0017091) |
0.1 | 15.6 | GO:0046982 | protein heterodimerization activity(GO:0046982) |
0.1 | 0.7 | GO:0016783 | sulfurtransferase activity(GO:0016783) |
0.1 | 0.7 | GO:0019843 | rRNA binding(GO:0019843) |
0.1 | 0.7 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
0.1 | 0.6 | GO:0017070 | U6 snRNA binding(GO:0017070) |
0.1 | 1.3 | GO:0016891 | endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891) |
0.0 | 0.3 | GO:0019215 | intermediate filament binding(GO:0019215) |
0.0 | 0.3 | GO:0015114 | phosphate ion transmembrane transporter activity(GO:0015114) |
0.0 | 0.2 | GO:0034511 | U3 snoRNA binding(GO:0034511) |
0.0 | 0.2 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
0.0 | 1.6 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
0.0 | 0.6 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
0.0 | 0.1 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
0.0 | 0.3 | GO:0016723 | oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723) |
0.0 | 0.8 | GO:0032947 | protein complex scaffold(GO:0032947) |
0.0 | 0.9 | GO:0000049 | tRNA binding(GO:0000049) |
0.0 | 0.9 | GO:0051082 | unfolded protein binding(GO:0051082) |
0.0 | 0.2 | GO:0005537 | mannose binding(GO:0005537) |
0.0 | 0.4 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
0.0 | 0.1 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
4.1 | 57.2 | SA_REG_CASCADE_OF_CYCLIN_EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
3.4 | 187.7 | PID_SYNDECAN_1_PATHWAY | Syndecan-1-mediated signaling events |
3.4 | 156.4 | PID_ATR_PATHWAY | ATR signaling pathway |
2.5 | 7.4 | SA_G2_AND_M_PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
2.4 | 202.8 | PID_E2F_PATHWAY | E2F transcription factor network |
2.2 | 99.3 | PID_AURORA_B_PATHWAY | Aurora B signaling |
1.9 | 46.6 | PID_FOXM1_PATHWAY | FOXM1 transcription factor network |
1.8 | 12.6 | PID_INTEGRIN4_PATHWAY | Alpha6 beta4 integrin-ligand interactions |
1.5 | 17.9 | PID_VEGF_VEGFR_PATHWAY | VEGF and VEGFR signaling network |
1.4 | 41.7 | PID_FANCONI_PATHWAY | Fanconi anemia pathway |
1.4 | 27.5 | PID_SYNDECAN_2_PATHWAY | Syndecan-2-mediated signaling events |
1.3 | 6.7 | SA_G1_AND_S_PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
1.2 | 40.4 | PID_DELTA_NP63_PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
1.1 | 30.8 | ST_GA12_PATHWAY | G alpha 12 Pathway |
1.0 | 30.0 | PID_HEDGEHOG_2PATHWAY | Signaling events mediated by the Hedgehog family |
0.9 | 8.5 | PID_SMAD2_3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
0.8 | 8.2 | PID_BARD1_PATHWAY | BARD1 signaling events |
0.8 | 27.1 | PID_RAS_PATHWAY | Regulation of Ras family activation |
0.7 | 39.8 | PID_ARF6_TRAFFICKING_PATHWAY | Arf6 trafficking events |
0.7 | 15.0 | PID_GLYPICAN_1PATHWAY | Glypican 1 network |
0.7 | 6.4 | PID_RANBP2_PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
0.7 | 27.6 | PID_HNF3B_PATHWAY | FOXA2 and FOXA3 transcription factor networks |
0.7 | 39.3 | PID_SMAD2_3NUCLEAR_PATHWAY | Regulation of nuclear SMAD2/3 signaling |
0.7 | 30.3 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
0.7 | 55.1 | PID_AR_PATHWAY | Coregulation of Androgen receptor activity |
0.7 | 27.8 | PID_FGF_PATHWAY | FGF signaling pathway |
0.7 | 63.6 | PID_MYC_ACTIV_PATHWAY | Validated targets of C-MYC transcriptional activation |
0.6 | 18.0 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
0.6 | 31.6 | PID_CMYB_PATHWAY | C-MYB transcription factor network |
0.6 | 6.4 | PID_NEPHRIN_NEPH1_PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
0.5 | 10.4 | PID_ATM_PATHWAY | ATM pathway |
0.5 | 8.0 | PID_ERBB4_PATHWAY | ErbB4 signaling events |
0.5 | 19.4 | PID_BMP_PATHWAY | BMP receptor signaling |
0.4 | 12.3 | ST_T_CELL_SIGNAL_TRANSDUCTION | T Cell Signal Transduction |
0.4 | 5.7 | PID_INTEGRIN2_PATHWAY | Beta2 integrin cell surface interactions |
0.4 | 7.0 | PID_PRL_SIGNALING_EVENTS_PATHWAY | Signaling events mediated by PRL |
0.4 | 15.9 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
0.4 | 7.3 | PID_WNT_NONCANONICAL_PATHWAY | Noncanonical Wnt signaling pathway |
0.4 | 16.6 | PID_PLK1_PATHWAY | PLK1 signaling events |
0.4 | 8.0 | PID_NECTIN_PATHWAY | Nectin adhesion pathway |
0.4 | 9.5 | PID_TCR_CALCIUM_PATHWAY | Calcium signaling in the CD4+ TCR pathway |
0.4 | 5.3 | PID_SYNDECAN_4_PATHWAY | Syndecan-4-mediated signaling events |
0.4 | 11.2 | PID_FAS_PATHWAY | FAS (CD95) signaling pathway |
0.3 | 11.9 | PID_RAC1_PATHWAY | RAC1 signaling pathway |
0.3 | 10.9 | PID_AP1_PATHWAY | AP-1 transcription factor network |
0.3 | 2.9 | ST_GRANULE_CELL_SURVIVAL_PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
0.3 | 2.6 | PID_TRAIL_PATHWAY | TRAIL signaling pathway |
0.3 | 5.5 | PID_ATF2_PATHWAY | ATF-2 transcription factor network |
0.3 | 6.0 | PID_FAK_PATHWAY | Signaling events mediated by focal adhesion kinase |
0.3 | 9.0 | PID_TELOMERASE_PATHWAY | Regulation of Telomerase |
0.3 | 7.5 | PID_CDC42_PATHWAY | CDC42 signaling events |
0.2 | 4.9 | PID_RB_1PATHWAY | Regulation of retinoblastoma protein |
0.2 | 3.7 | PID_TCR_PATHWAY | TCR signaling in naïve CD4+ T cells |
0.2 | 27.4 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.2 | 1.6 | SIG_CD40PATHWAYMAP | Genes related to CD40 signaling |
0.2 | 3.3 | PID_IL1_PATHWAY | IL1-mediated signaling events |
0.2 | 22.5 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
0.2 | 1.7 | PID_HDAC_CLASSIII_PATHWAY | Signaling events mediated by HDAC Class III |
0.2 | 5.7 | PID_TRKR_PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
0.1 | 17.8 | NABA_SECRETED_FACTORS | Genes encoding secreted soluble factors |
0.1 | 4.8 | PID_HIF1_TFPATHWAY | HIF-1-alpha transcription factor network |
0.1 | 1.8 | PID_RET_PATHWAY | Signaling events regulated by Ret tyrosine kinase |
0.1 | 4.6 | PID_MTOR_4PATHWAY | mTOR signaling pathway |
0.1 | 1.5 | PID_REG_GR_PATHWAY | Glucocorticoid receptor regulatory network |
0.1 | 0.7 | PID_INTEGRIN1_PATHWAY | Beta1 integrin cell surface interactions |
0.1 | 1.1 | PID_CERAMIDE_PATHWAY | Ceramide signaling pathway |
0.1 | 0.9 | PID_A6B1_A6B4_INTEGRIN_PATHWAY | a6b1 and a6b4 Integrin signaling |
0.0 | 1.4 | PID_CASPASE_PATHWAY | Caspase cascade in apoptosis |
0.0 | 0.3 | PID_CXCR4_PATHWAY | CXCR4-mediated signaling events |
0.0 | 0.6 | PID_ALK1_PATHWAY | ALK1 signaling events |
0.0 | 0.2 | PID_HIF1A_PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
8.0 | 128.1 | REACTOME_UNWINDING_OF_DNA | Genes involved in Unwinding of DNA |
6.5 | 6.5 | REACTOME_SCFSKP2_MEDIATED_DEGRADATION_OF_P27_P21 | Genes involved in SCF(Skp2)-mediated degradation of p27/p21 |
5.6 | 101.1 | REACTOME_G1_S_SPECIFIC_TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
5.6 | 72.7 | REACTOME_PROCESSIVE_SYNTHESIS_ON_THE_LAGGING_STRAND | Genes involved in Processive synthesis on the lagging strand |
5.0 | 20.1 | REACTOME_DNA_STRAND_ELONGATION | Genes involved in DNA strand elongation |
4.8 | 43.6 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PS | Genes involved in Acyl chain remodelling of PS |
4.6 | 78.9 | REACTOME_G0_AND_EARLY_G1 | Genes involved in G0 and Early G1 |
3.8 | 86.3 | REACTOME_HS_GAG_DEGRADATION | Genes involved in HS-GAG degradation |
3.6 | 81.8 | REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
3.4 | 188.9 | REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
3.1 | 28.0 | REACTOME_SIGNALING_BY_FGFR3_MUTANTS | Genes involved in Signaling by FGFR3 mutants |
3.0 | 143.0 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
3.0 | 14.8 | REACTOME_ACTIVATED_POINT_MUTANTS_OF_FGFR2 | Genes involved in Activated point mutants of FGFR2 |
2.8 | 19.8 | REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
2.8 | 19.6 | REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
2.8 | 5.5 | REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
2.4 | 19.1 | REACTOME_TRANSPORT_OF_ORGANIC_ANIONS | Genes involved in Transport of organic anions |
1.9 | 24.4 | REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
1.8 | 25.6 | REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
1.7 | 20.6 | REACTOME_FANCONI_ANEMIA_PATHWAY | Genes involved in Fanconi Anemia pathway |
1.6 | 33.5 | REACTOME_SIGNALING_BY_NODAL | Genes involved in Signaling by NODAL |
1.5 | 17.9 | REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
1.4 | 17.3 | REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX | Genes involved in Activation of the pre-replicative complex |
1.4 | 11.2 | REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
1.3 | 22.1 | REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
1.3 | 31.1 | REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
1.2 | 8.3 | REACTOME_ENDOGENOUS_STEROLS | Genes involved in Endogenous sterols |
1.0 | 3.0 | REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
1.0 | 13.7 | REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
1.0 | 7.8 | REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
0.9 | 13.2 | REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS | Genes involved in p130Cas linkage to MAPK signaling for integrins |
0.9 | 18.8 | REACTOME_PYRIMIDINE_METABOLISM | Genes involved in Pyrimidine metabolism |
0.9 | 14.4 | REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
0.8 | 13.4 | REACTOME_METABOLISM_OF_POLYAMINES | Genes involved in Metabolism of polyamines |
0.8 | 19.1 | REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
0.7 | 26.9 | REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION | Genes involved in Nuclear Events (kinase and transcription factor activation) |
0.7 | 7.0 | REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
0.7 | 7.0 | REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS | Genes involved in Regulation of gene expression in beta cells |
0.7 | 5.6 | REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
0.7 | 18.2 | REACTOME_KINESINS | Genes involved in Kinesins |
0.7 | 7.4 | REACTOME_AMINE_DERIVED_HORMONES | Genes involved in Amine-derived hormones |
0.6 | 46.1 | REACTOME_MITOTIC_G2_G2_M_PHASES | Genes involved in Mitotic G2-G2/M phases |
0.6 | 52.6 | REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS | Genes involved in Peptide ligand-binding receptors |
0.6 | 34.1 | REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
0.6 | 18.1 | REACTOME_SYNTHESIS_OF_PA | Genes involved in Synthesis of PA |
0.5 | 14.9 | REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
0.5 | 13.3 | REACTOME_METAL_ION_SLC_TRANSPORTERS | Genes involved in Metal ion SLC transporters |
0.5 | 8.9 | REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS | Genes involved in Amine compound SLC transporters |
0.5 | 11.1 | REACTOME_REGULATORY_RNA_PATHWAYS | Genes involved in Regulatory RNA pathways |
0.5 | 32.6 | REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS | Genes involved in Integrin cell surface interactions |
0.5 | 4.3 | REACTOME_TRYPTOPHAN_CATABOLISM | Genes involved in Tryptophan catabolism |
0.5 | 6.1 | REACTOME_REGULATION_OF_APOPTOSIS | Genes involved in Regulation of Apoptosis |
0.5 | 11.7 | REACTOME_SIGNALING_BY_BMP | Genes involved in Signaling by BMP |
0.4 | 33.9 | REACTOME_MITOTIC_PROMETAPHASE | Genes involved in Mitotic Prometaphase |
0.4 | 17.6 | REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS | Genes involved in O-linked glycosylation of mucins |
0.4 | 5.2 | REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
0.4 | 3.0 | REACTOME_EXTENSION_OF_TELOMERES | Genes involved in Extension of Telomeres |
0.4 | 7.5 | REACTOME_SULFUR_AMINO_ACID_METABOLISM | Genes involved in Sulfur amino acid metabolism |
0.4 | 9.8 | REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION | Genes involved in Unblocking of NMDA receptor, glutamate binding and activation |
0.4 | 6.3 | REACTOME_RNA_POL_III_CHAIN_ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
0.4 | 14.3 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | Genes involved in Ion transport by P-type ATPases |
0.4 | 9.6 | REACTOME_STRIATED_MUSCLE_CONTRACTION | Genes involved in Striated Muscle Contraction |
0.4 | 9.0 | REACTOME_CHOLESTEROL_BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
0.4 | 2.2 | REACTOME_RNA_POL_I_PROMOTER_OPENING | Genes involved in RNA Polymerase I Promoter Opening |
0.3 | 13.1 | REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE | Genes involved in GPVI-mediated activation cascade |
0.3 | 8.9 | REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
0.3 | 7.6 | REACTOME_AMYLOIDS | Genes involved in Amyloids |
0.3 | 3.9 | REACTOME_GAP_JUNCTION_ASSEMBLY | Genes involved in Gap junction assembly |
0.3 | 36.6 | REACTOME_MRNA_SPLICING | Genes involved in mRNA Splicing |
0.3 | 2.5 | REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING | Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling |
0.3 | 4.0 | REACTOME_MEIOTIC_RECOMBINATION | Genes involved in Meiotic Recombination |
0.3 | 18.4 | REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION | Genes involved in Antigen processing-Cross presentation |
0.3 | 2.8 | REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
0.3 | 4.3 | REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
0.2 | 8.9 | REACTOME_GLYCOLYSIS | Genes involved in Glycolysis |
0.2 | 20.0 | REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
0.2 | 0.5 | REACTOME_ABORTIVE_ELONGATION_OF_HIV1_TRANSCRIPT_IN_THE_ABSENCE_OF_TAT | Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat |
0.2 | 8.0 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
0.2 | 15.5 | REACTOME_APOPTOTIC_EXECUTION_PHASE | Genes involved in Apoptotic execution phase |
0.2 | 11.9 | REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT | Genes involved in Mitochondrial Protein Import |
0.2 | 1.5 | REACTOME_RECYCLING_PATHWAY_OF_L1 | Genes involved in Recycling pathway of L1 |
0.2 | 4.4 | REACTOME_METABOLISM_OF_PORPHYRINS | Genes involved in Metabolism of porphyrins |
0.2 | 8.8 | REACTOME_NETRIN1_SIGNALING | Genes involved in Netrin-1 signaling |
0.2 | 1.7 | REACTOME_RNA_POL_I_TRANSCRIPTION_INITIATION | Genes involved in RNA Polymerase I Transcription Initiation |
0.2 | 3.8 | REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
0.2 | 2.2 | REACTOME_GENERIC_TRANSCRIPTION_PATHWAY | Genes involved in Generic Transcription Pathway |
0.2 | 12.0 | REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION | Genes involved in Influenza Viral RNA Transcription and Replication |
0.2 | 11.4 | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT | Genes involved in Respiratory electron transport |
0.2 | 2.9 | REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS | Genes involved in CREB phosphorylation through the activation of Ras |
0.2 | 5.7 | REACTOME_METABOLISM_OF_NON_CODING_RNA | Genes involved in Metabolism of non-coding RNA |
0.1 | 2.2 | REACTOME_NEPHRIN_INTERACTIONS | Genes involved in Nephrin interactions |
0.1 | 2.7 | REACTOME_DEADENYLATION_OF_MRNA | Genes involved in Deadenylation of mRNA |
0.1 | 1.4 | REACTOME_G_ALPHA1213_SIGNALLING_EVENTS | Genes involved in G alpha (12/13) signalling events |
0.1 | 3.5 | REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
0.1 | 3.0 | REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE | Genes involved in Late Phase of HIV Life Cycle |
0.1 | 1.1 | REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
0.1 | 2.3 | REACTOME_SIGNALLING_TO_ERKS | Genes involved in Signalling to ERKs |
0.1 | 2.2 | REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX | Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex |
0.1 | 1.1 | REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
0.1 | 1.9 | REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
0.1 | 1.2 | REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL | Genes involved in AKT phosphorylates targets in the cytosol |
0.1 | 2.4 | REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |
0.1 | 1.8 | REACTOME_MYOGENESIS | Genes involved in Myogenesis |
0.1 | 0.8 | REACTOME_CALNEXIN_CALRETICULIN_CYCLE | Genes involved in Calnexin/calreticulin cycle |
0.1 | 2.2 | REACTOME_SIGNALING_BY_PDGF | Genes involved in Signaling by PDGF |
0.1 | 2.2 | REACTOME_TRANSPORT_OF_GLUCOSE_AND_OTHER_SUGARS_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS | Genes involved in Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds |
0.1 | 1.2 | REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
0.1 | 0.7 | REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol |
0.1 | 3.8 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
0.1 | 1.3 | REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
0.0 | 9.7 | REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
0.0 | 0.6 | REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS | Genes involved in Nucleotide-like (purinergic) receptors |
0.0 | 1.9 | REACTOME_TRANSLATION | Genes involved in Translation |
0.0 | 0.8 | REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
0.0 | 0.2 | REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
0.0 | 0.3 | REACTOME_COPI_MEDIATED_TRANSPORT | Genes involved in COPI Mediated Transport |
0.0 | 0.2 | REACTOME_P75NTR_RECRUITS_SIGNALLING_COMPLEXES | Genes involved in p75NTR recruits signalling complexes |