Motif ID: Hoxa13

Z-value: 0.688


Transcription factors associated with Hoxa13:

Gene SymbolEntrez IDGene Name
Hoxa13 ENSMUSG00000038203.12 Hoxa13



Activity profile for motif Hoxa13.

activity profile for motif Hoxa13


Sorted Z-values histogram for motif Hoxa13

Sorted Z-values for motif Hoxa13



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa13

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_144893127 2.814 ENSMUST00000142808.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr4_-_154636831 2.767 ENSMUST00000030902.6
ENSMUST00000105637.1
ENSMUST00000070313.7
ENSMUST00000105636.1
ENSMUST00000105638.2
ENSMUST00000097759.2
ENSMUST00000124771.1
Prdm16






PR domain containing 16






chr3_-_49757257 2.699 ENSMUST00000035931.7
Pcdh18
protocadherin 18
chr17_+_75178797 2.581 ENSMUST00000112516.1
ENSMUST00000135447.1
Ltbp1

latent transforming growth factor beta binding protein 1

chrY_-_1286563 2.427 ENSMUST00000091190.5
Ddx3y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr1_-_45503282 2.424 ENSMUST00000086430.4
Col5a2
collagen, type V, alpha 2
chr17_+_75178911 2.255 ENSMUST00000112514.1
Ltbp1
latent transforming growth factor beta binding protein 1
chrX_+_82948861 2.184 ENSMUST00000114000.1
Dmd
dystrophin, muscular dystrophy
chr6_-_125494754 2.116 ENSMUST00000032492.8
Cd9
CD9 antigen
chr5_+_117841839 2.080 ENSMUST00000142742.2
Nos1
nitric oxide synthase 1, neuronal
chr15_+_83791939 2.003 ENSMUST00000172115.1
ENSMUST00000172398.1
Mpped1

metallophosphoesterase domain containing 1

chr2_+_126215100 1.990 ENSMUST00000164042.2
Gm17555
predicted gene, 17555
chr15_+_3270767 1.957 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
Sepp1



selenoprotein P, plasma, 1



chr6_+_125215551 1.912 ENSMUST00000032487.7
ENSMUST00000100942.2
ENSMUST00000063588.8
Vamp1


vesicle-associated membrane protein 1


chr16_-_31314804 1.893 ENSMUST00000115230.1
ENSMUST00000130560.1
Apod

apolipoprotein D

chr3_-_80802789 1.875 ENSMUST00000107745.1
ENSMUST00000075316.4
Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr10_-_116972609 1.857 ENSMUST00000092165.4
Gm10271
predicted gene 10271
chr17_-_35074485 1.766 ENSMUST00000007259.3
Ly6g6d
lymphocyte antigen 6 complex, locus G6D
chr1_-_173942445 1.741 ENSMUST00000042228.8
ENSMUST00000081216.5
ENSMUST00000129829.1
ENSMUST00000123708.1
ENSMUST00000111210.2
Ifi203



Mndal
interferon activated gene 203



myeloid nuclear differentiation antigen like
chr5_-_62766153 1.733 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr8_+_84723003 1.730 ENSMUST00000098571.4
G430095P16Rik
RIKEN cDNA G430095P16 gene
chrX_+_141475385 1.728 ENSMUST00000112931.1
ENSMUST00000112930.1
Col4a5

collagen, type IV, alpha 5

chr13_+_94083490 1.711 ENSMUST00000156071.1
Lhfpl2
lipoma HMGIC fusion partner-like 2
chr2_-_63184253 1.663 ENSMUST00000075052.3
ENSMUST00000112454.1
Kcnh7

potassium voltage-gated channel, subfamily H (eag-related), member 7

chr19_-_5796924 1.590 ENSMUST00000174808.1
Malat1
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chr1_-_56969864 1.553 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr13_-_23430826 1.553 ENSMUST00000153753.1
ENSMUST00000141543.1
C230035I16Rik

RIKEN cDNA C230035I16 gene

chr16_+_15317458 1.550 ENSMUST00000178312.1
Gm21897
predicted gene, 21897
chr16_+_82828382 1.488 ENSMUST00000177665.1
Gm21833
predicted gene, 21833
chr14_+_73661225 1.485 ENSMUST00000098874.3
Gm21750
predicted gene, 21750
chr13_-_84064772 1.467 ENSMUST00000182477.1
Gm17750
predicted gene, 17750
chr18_+_69593361 1.467 ENSMUST00000114978.2
ENSMUST00000114977.1
Tcf4

transcription factor 4

chr3_+_137671524 1.461 ENSMUST00000166899.2
Gm21962
predicted gene, 21962
chr10_+_97479470 1.419 ENSMUST00000105287.3
Dcn
decorin
chr11_-_109473220 1.347 ENSMUST00000070872.6
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr8_-_45975224 1.343 ENSMUST00000095323.1
ENSMUST00000098786.2
1700029J07Rik

RIKEN cDNA 1700029J07 gene

chr5_+_64812336 1.334 ENSMUST00000166409.1
Klf3
Kruppel-like factor 3 (basic)
chr3_+_66985680 1.313 ENSMUST00000065047.6
Rsrc1
arginine/serine-rich coiled-coil 1
chr7_+_4119525 1.179 ENSMUST00000119661.1
ENSMUST00000129423.1
Ttyh1

tweety homolog 1 (Drosophila)

chr8_+_94179089 1.176 ENSMUST00000034215.6
Mt1
metallothionein 1
chr7_+_4119556 1.168 ENSMUST00000079415.5
Ttyh1
tweety homolog 1 (Drosophila)
chr2_-_63184170 1.146 ENSMUST00000112452.1
Kcnh7
potassium voltage-gated channel, subfamily H (eag-related), member 7
chrX_+_106920618 1.135 ENSMUST00000060576.7
Lpar4
lysophosphatidic acid receptor 4
chr1_-_56969827 1.128 ENSMUST00000176759.1
Satb2
special AT-rich sequence binding protein 2
chr2_-_33942111 1.121 ENSMUST00000130988.1
ENSMUST00000127936.1
ENSMUST00000134271.1
Gm13403


predicted gene 13403


chr4_-_88033328 1.089 ENSMUST00000078090.5
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chrM_+_11734 1.073 ENSMUST00000082418.1
mt-Nd5
mitochondrially encoded NADH dehydrogenase 5
chr7_-_44670820 1.071 ENSMUST00000048102.7
Myh14
myosin, heavy polypeptide 14
chr7_+_103550368 1.058 ENSMUST00000106888.1
Olfr613
olfactory receptor 613
chrX_-_109013389 1.036 ENSMUST00000033597.8
Hmgn5
high-mobility group nucleosome binding domain 5
chr14_+_28511344 1.029 ENSMUST00000112272.1
Wnt5a
wingless-related MMTV integration site 5A
chr11_-_109472611 1.010 ENSMUST00000168740.1
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr9_-_64022043 1.004 ENSMUST00000041029.5
Smad6
SMAD family member 6
chr6_+_29694204 1.001 ENSMUST00000046750.7
ENSMUST00000115250.3
Tspan33

tetraspanin 33

chr3_+_62419668 1.000 ENSMUST00000161057.1
Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr7_+_127800604 0.997 ENSMUST00000046863.5
ENSMUST00000106272.1
ENSMUST00000139068.1
Hsd3b7


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7


chr10_-_105574435 0.995 ENSMUST00000061506.8
Tmtc2
transmembrane and tetratricopeptide repeat containing 2
chr15_+_9436028 0.960 ENSMUST00000042360.3
Capsl
calcyphosine-like
chr15_+_25773985 0.954 ENSMUST00000125667.1
Myo10
myosin X
chr4_+_119814495 0.947 ENSMUST00000106307.2
Hivep3
human immunodeficiency virus type I enhancer binding protein 3
chr18_-_78206408 0.944 ENSMUST00000163367.1
Slc14a2
solute carrier family 14 (urea transporter), member 2
chr1_-_36273425 0.943 ENSMUST00000056946.6
Neurl3
neuralized homolog 3 homolog (Drosophila)
chrM_+_3906 0.940 ENSMUST00000082396.1
mt-Nd2
mitochondrially encoded NADH dehydrogenase 2
chr9_-_116175318 0.937 ENSMUST00000061101.4
ENSMUST00000035014.6
Tgfbr2

transforming growth factor, beta receptor II

chrX_+_136741821 0.930 ENSMUST00000089350.4
BC065397
cDNA sequence BC065397
chr9_-_54661870 0.924 ENSMUST00000034822.5
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr5_-_70842617 0.921 ENSMUST00000031119.1
Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr16_-_23988852 0.892 ENSMUST00000023151.5
Bcl6
B cell leukemia/lymphoma 6
chr12_+_112620030 0.891 ENSMUST00000180015.1
ENSMUST00000021726.6
Adssl1

adenylosuccinate synthetase like 1

chr4_-_82850721 0.888 ENSMUST00000139401.1
Zdhhc21
zinc finger, DHHC domain containing 21
chr2_+_19344820 0.883 ENSMUST00000150514.1
ENSMUST00000136456.1
4930447M23Rik

RIKEN cDNA 4930447M23 gene

chr6_+_80018877 0.877 ENSMUST00000147663.1
ENSMUST00000128718.1
ENSMUST00000126005.1
ENSMUST00000133918.1
Lrrtm4



leucine rich repeat transmembrane neuronal 4



chr7_+_30565410 0.872 ENSMUST00000043850.7
Igflr1
IGF-like family receptor 1
chr4_-_3938354 0.858 ENSMUST00000003369.3
Plag1
pleiomorphic adenoma gene 1
chr11_+_70657196 0.830 ENSMUST00000157027.1
ENSMUST00000072841.5
ENSMUST00000108548.1
ENSMUST00000126241.1
Eno3



enolase 3, beta muscle



chr9_-_44799179 0.828 ENSMUST00000114705.1
ENSMUST00000002100.7
Tmem25

transmembrane protein 25

chr7_-_41499890 0.814 ENSMUST00000098509.3
AW146154
expressed sequence AW146154
chrY_+_897782 0.810 ENSMUST00000055032.7
Kdm5d
lysine (K)-specific demethylase 5D
chr17_-_6477102 0.774 ENSMUST00000167717.2
Tmem181b-ps
transmembrane protein 181B, pseudogene
chr2_+_3424123 0.771 ENSMUST00000061852.5
ENSMUST00000100463.3
ENSMUST00000102988.3
ENSMUST00000115066.1
Dclre1c



DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae)



chr7_+_41599250 0.763 ENSMUST00000163475.1
2610021A01Rik
RIKEN cDNA 2610021A01 gene
chr6_+_80019008 0.751 ENSMUST00000126399.1
ENSMUST00000136421.1
Lrrtm4

leucine rich repeat transmembrane neuronal 4

chr8_+_129118043 0.734 ENSMUST00000108744.1
1700008F21Rik
RIKEN cDNA 1700008F21 gene
chr4_-_6454262 0.716 ENSMUST00000029910.5
Nsmaf
neutral sphingomyelinase (N-SMase) activation associated factor
chr17_+_56764738 0.683 ENSMUST00000007747.8
Dus3l
dihydrouridine synthase 3-like (S. cerevisiae)
chr1_-_44218952 0.674 ENSMUST00000054801.3
Mettl21e
methyltransferase like 21E
chr13_-_64312676 0.672 ENSMUST00000021938.9
Aaed1
AhpC/TSA antioxidant enzyme domain containing 1
chr9_-_22208546 0.672 ENSMUST00000167359.1
1810064F22Rik
RIKEN cDNA 1810064F22 gene
chr6_-_97617536 0.671 ENSMUST00000113355.2
Frmd4b
FERM domain containing 4B
chr17_-_10320229 0.661 ENSMUST00000053066.6
Qk
quaking
chr10_-_13324160 0.659 ENSMUST00000105545.4
Phactr2
phosphatase and actin regulator 2
chr13_+_37345338 0.659 ENSMUST00000021860.5
Ly86
lymphocyte antigen 86
chr16_-_91728701 0.656 ENSMUST00000114023.2
ENSMUST00000117644.1
Cryzl1

crystallin, zeta (quinone reductase)-like 1

chr7_-_37772868 0.654 ENSMUST00000176205.1
Zfp536
zinc finger protein 536
chrM_-_14060 0.650 ENSMUST00000082419.1
mt-Nd6
mitochondrially encoded NADH dehydrogenase 6
chr5_-_107289561 0.645 ENSMUST00000031224.8
Tgfbr3
transforming growth factor, beta receptor III
chr3_+_5218546 0.640 ENSMUST00000026284.6
Zfhx4
zinc finger homeodomain 4
chr7_+_45526330 0.637 ENSMUST00000120985.1
ENSMUST00000051810.8
Plekha4

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4

chr11_+_108587077 0.633 ENSMUST00000146912.2
Cep112
centrosomal protein 112
chr17_-_26095487 0.631 ENSMUST00000025007.5
Nme4
NME/NM23 nucleoside diphosphate kinase 4
chr2_+_104065826 0.627 ENSMUST00000104891.1
Gm10912
predicted gene 10912
chr17_+_6270475 0.607 ENSMUST00000088940.4
Tmem181a
transmembrane protein 181A
chr17_+_57249450 0.606 ENSMUST00000019631.9
Trip10
thyroid hormone receptor interactor 10
chr3_+_89266552 0.593 ENSMUST00000040824.1
Dpm3
dolichyl-phosphate mannosyltransferase polypeptide 3
chr12_-_72085393 0.592 ENSMUST00000019862.2
L3hypdh
L-3-hydroxyproline dehydratase (trans-)
chr8_+_46163651 0.586 ENSMUST00000034048.6
ENSMUST00000145229.1
4933411K20Rik

RIKEN cDNA 4933411K20 gene

chr2_+_16356744 0.586 ENSMUST00000114703.3
Plxdc2
plexin domain containing 2
chr12_+_80945500 0.583 ENSMUST00000094693.4
Srsf5
serine/arginine-rich splicing factor 5
chr7_-_73537621 0.582 ENSMUST00000172704.1
Chd2
chromodomain helicase DNA binding protein 2
chr1_-_105659008 0.582 ENSMUST00000070699.8
Pign
phosphatidylinositol glycan anchor biosynthesis, class N
chr17_-_6621267 0.564 ENSMUST00000115772.3
Tmem181c-ps
transmembrane protein 181C, pseudogene
chr18_+_37341702 0.564 ENSMUST00000053037.3
Pcdhb7
protocadherin beta 7
chr7_-_3677509 0.561 ENSMUST00000038743.8
Tmc4
transmembrane channel-like gene family 4
chr4_+_133130505 0.552 ENSMUST00000084241.5
ENSMUST00000138831.1
Wasf2

WAS protein family, member 2

chr1_+_59256906 0.551 ENSMUST00000160662.1
ENSMUST00000114248.2
Cdk15

cyclin-dependent kinase 15

chr2_-_91236877 0.549 ENSMUST00000111352.1
Ddb2
damage specific DNA binding protein 2
chr9_+_35423582 0.546 ENSMUST00000154652.1
Cdon
cell adhesion molecule-related/down-regulated by oncogenes
chr13_-_74376566 0.546 ENSMUST00000091481.2
Zfp72
zinc finger protein 72
chr3_-_116614587 0.543 ENSMUST00000041524.4
Trmt13
tRNA methyltransferase 13
chr11_-_62392605 0.539 ENSMUST00000151498.2
ENSMUST00000159069.1
Ncor1

nuclear receptor co-repressor 1

chr5_-_48754521 0.531 ENSMUST00000101214.2
ENSMUST00000176191.1
Kcnip4

Kv channel interacting protein 4

chr2_-_76673039 0.530 ENSMUST00000002809.7
Fkbp7
FK506 binding protein 7
chr4_+_148140699 0.526 ENSMUST00000140049.1
ENSMUST00000105707.1
Mad2l2

MAD2 mitotic arrest deficient-like 2

chr4_-_92191749 0.525 ENSMUST00000123179.1
Gm12666
predicted gene 12666
chr13_-_55100248 0.513 ENSMUST00000026997.5
ENSMUST00000127195.1
ENSMUST00000099496.3
Uimc1


ubiquitin interaction motif containing 1


chr4_-_120951664 0.513 ENSMUST00000106280.1
Zfp69
zinc finger protein 69
chr6_+_8520008 0.511 ENSMUST00000162567.1
ENSMUST00000161217.1
Glcci1

glucocorticoid induced transcript 1

chr3_+_5218589 0.510 ENSMUST00000177488.1
Zfhx4
zinc finger homeodomain 4
chr7_-_42505695 0.502 ENSMUST00000174407.1
Zfp141
zinc finger protein 141
chr16_+_43889896 0.501 ENSMUST00000122014.1
ENSMUST00000178400.1
2610015P09Rik

RIKEN cDNA 2610015P09 gene

chr5_+_107497718 0.500 ENSMUST00000112671.2
A830010M20Rik
RIKEN cDNA A830010M20 gene
chr13_+_80883403 0.500 ENSMUST00000099356.2
Arrdc3
arrestin domain containing 3
chr19_+_34922351 0.498 ENSMUST00000087341.5
Kif20b
kinesin family member 20B
chr4_+_42240639 0.498 ENSMUST00000117202.2
Gm10600
predicted gene 10600
chr15_-_58214882 0.495 ENSMUST00000022986.6
Fbxo32
F-box protein 32
chr3_+_40540751 0.494 ENSMUST00000091186.3
Intu
inturned planar cell polarity effector homolog (Drosophila)
chr1_+_173420567 0.491 ENSMUST00000173023.1
Aim2
absent in melanoma 2
chr3_+_5218516 0.490 ENSMUST00000175866.1
Zfhx4
zinc finger homeodomain 4
chr1_-_97128249 0.485 ENSMUST00000027569.7
Slco6c1
solute carrier organic anion transporter family, member 6c1
chr9_-_13245741 0.485 ENSMUST00000110582.2
Jrkl
jerky homolog-like (mouse)
chr6_-_22356176 0.484 ENSMUST00000081288.7
Fam3c
family with sequence similarity 3, member C
chr3_+_98280427 0.477 ENSMUST00000090746.2
ENSMUST00000120541.1
Hmgcs2

3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2

chr19_-_6987621 0.476 ENSMUST00000130048.1
ENSMUST00000025914.6
Vegfb

vascular endothelial growth factor B

chr9_-_123678782 0.474 ENSMUST00000170591.1
ENSMUST00000171647.1
Slc6a20a

solute carrier family 6 (neurotransmitter transporter), member 20A

chr12_+_33957645 0.474 ENSMUST00000049089.5
Twist1
twist basic helix-loop-helix transcription factor 1
chr6_+_48739039 0.469 ENSMUST00000054368.4
ENSMUST00000140054.1
Gimap1

GTPase, IMAP family member 1

chr4_-_97183166 0.464 ENSMUST00000086672.2
Gm10192
predicted gene 10192
chr2_+_35132194 0.458 ENSMUST00000113034.1
ENSMUST00000113037.3
ENSMUST00000113033.2
Cep110


centrosomal protein 110


chr16_+_91225550 0.457 ENSMUST00000035608.8
Olig2
oligodendrocyte transcription factor 2
chr15_-_11037968 0.456 ENSMUST00000058007.5
Rxfp3
relaxin family peptide receptor 3
chr19_-_56548122 0.449 ENSMUST00000026063.5
ENSMUST00000182276.1
Dclre1a

DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae)

chrX_+_101532734 0.448 ENSMUST00000118878.1
ENSMUST00000101341.2
ENSMUST00000149274.1
Taf1


TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor


chr16_+_43889800 0.439 ENSMUST00000132859.1
2610015P09Rik
RIKEN cDNA 2610015P09 gene
chr2_+_133552159 0.438 ENSMUST00000028836.6
Bmp2
bone morphogenetic protein 2
chr17_+_45433823 0.436 ENSMUST00000181149.1
B230354K17Rik
RIKEN cDNA B230354K17 gene
chr8_+_46163733 0.436 ENSMUST00000110376.1
4933411K20Rik
RIKEN cDNA 4933411K20 gene
chr4_-_133967296 0.425 ENSMUST00000105893.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr9_-_37147257 0.417 ENSMUST00000039674.5
ENSMUST00000080754.5
Pknox2

Pbx/knotted 1 homeobox 2

chr4_+_100776664 0.415 ENSMUST00000030257.8
ENSMUST00000097955.2
Cachd1

cache domain containing 1

chr6_+_129180613 0.415 ENSMUST00000032260.5
Clec2d
C-type lectin domain family 2, member d
chr4_+_41762309 0.412 ENSMUST00000108042.2
Il11ra1
interleukin 11 receptor, alpha chain 1
chr2_-_29787622 0.411 ENSMUST00000177467.1
ENSMUST00000113807.3
Trub2

TruB pseudouridine (psi) synthase homolog 2 (E. coli)

chr1_-_162866502 0.407 ENSMUST00000046049.7
Fmo1
flavin containing monooxygenase 1
chrX_+_99042581 0.406 ENSMUST00000036606.7
Stard8
START domain containing 8
chr12_+_59129720 0.401 ENSMUST00000175912.1
ENSMUST00000176892.1
Ctage5

CTAGE family, member 5

chr17_-_25844417 0.398 ENSMUST00000176591.1
Rhot2
ras homolog gene family, member T2
chr8_+_95352258 0.396 ENSMUST00000034243.5
Mmp15
matrix metallopeptidase 15
chr11_+_69914179 0.393 ENSMUST00000057884.5
Gps2
G protein pathway suppressor 2
chr12_-_54986328 0.392 ENSMUST00000038926.6
Baz1a
bromodomain adjacent to zinc finger domain 1A
chr17_-_25844514 0.390 ENSMUST00000176709.1
Rhot2
ras homolog gene family, member T2
chr1_+_139422196 0.385 ENSMUST00000039867.7
Zbtb41
zinc finger and BTB domain containing 41 homolog
chr1_+_87403705 0.384 ENSMUST00000172736.1
Gigyf2
GRB10 interacting GYF protein 2
chr7_-_130772652 0.383 ENSMUST00000057134.4
Etos1
ectopic ossification 1
chr9_-_88438940 0.383 ENSMUST00000165315.1
ENSMUST00000173039.1
Snx14

sorting nexin 14

chr1_+_171895664 0.383 ENSMUST00000097466.2
Gm10521
predicted gene 10521
chr12_+_102128718 0.382 ENSMUST00000159329.1
Slc24a4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr6_-_97148908 0.382 ENSMUST00000142116.1
ENSMUST00000113387.1
Eogt

EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase

chr17_-_46327990 0.380 ENSMUST00000167360.1
Abcc10
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chr19_-_43674844 0.378 ENSMUST00000046038.7
Slc25a28
solute carrier family 25, member 28
chr4_+_11758147 0.377 ENSMUST00000029871.5
ENSMUST00000108303.1
Cdh17

cadherin 17

chr9_-_88438898 0.369 ENSMUST00000173011.1
ENSMUST00000174806.1
Snx14

sorting nexin 14

chr19_+_56548254 0.367 ENSMUST00000071423.5
Nhlrc2
NHL repeat containing 2
chr15_+_31224371 0.366 ENSMUST00000044524.9
Dap
death-associated protein
chr9_+_86485407 0.364 ENSMUST00000034987.8
Dopey1
dopey family member 1
chr11_-_70656467 0.363 ENSMUST00000131642.1
Gm12319
predicted gene 12319
chr13_-_23622502 0.362 ENSMUST00000062045.2
Hist1h1e
histone cluster 1, H1e
chr12_+_59129757 0.359 ENSMUST00000069430.8
ENSMUST00000177370.1
Ctage5

CTAGE family, member 5

chr4_-_42661893 0.352 ENSMUST00000108006.3
Il11ra2
interleukin 11 receptor, alpha chain 2
chr5_+_110839973 0.348 ENSMUST00000066160.1
Chek2
checkpoint kinase 2
chr5_+_137641334 0.348 ENSMUST00000177466.1
ENSMUST00000166099.2
Sap25

sin3 associated polypeptide

chr8_+_70172383 0.347 ENSMUST00000002413.8
ENSMUST00000182980.1
ENSMUST00000182365.1
Tmem161a


transmembrane protein 161A


chr5_+_22775630 0.345 ENSMUST00000179257.1
Gm21846
predicted gene, 21846
chr14_+_76504185 0.344 ENSMUST00000177207.1
Tsc22d1
TSC22 domain family, member 1
chr1_+_12692430 0.343 ENSMUST00000180062.1
ENSMUST00000177608.1
Sulf1

sulfatase 1

chr5_+_107497762 0.342 ENSMUST00000152474.1
ENSMUST00000060553.7
A830010M20Rik

RIKEN cDNA A830010M20 gene

chr3_+_66985647 0.339 ENSMUST00000162362.1
ENSMUST00000065074.7
Rsrc1

arginine/serine-rich coiled-coil 1

chr16_-_43889669 0.339 ENSMUST00000023387.7
Qtrtd1
queuine tRNA-ribosyltransferase domain containing 1
chr5_-_62765618 0.338 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr4_-_110290884 0.336 ENSMUST00000142722.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr1_-_59119748 0.334 ENSMUST00000087475.4
Tmem237
transmembrane protein 237

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.7 2.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.7 2.1 GO:0099548 drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738) retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by nitric oxide(GO:0099548)
0.6 1.9 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097) negative regulation of lymphocyte migration(GO:2000402)
0.4 0.4 GO:0003134 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134)
0.4 2.1 GO:0030913 paranodal junction assembly(GO:0030913)
0.3 2.8 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.3 1.0 GO:0061349 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) hypophysis morphogenesis(GO:0048850) cervix development(GO:0060067) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354)
0.3 1.6 GO:0035063 nuclear speck organization(GO:0035063)
0.3 0.9 GO:0071918 urea transmembrane transport(GO:0071918)
0.3 0.9 GO:0003274 endocardial cushion fusion(GO:0003274)
0.3 0.9 GO:0043379 memory T cell differentiation(GO:0043379)
0.3 0.9 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.3 2.8 GO:0042572 retinol metabolic process(GO:0042572)
0.3 1.0 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.2 0.2 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.2 0.5 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.2 0.4 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.2 0.6 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.2 1.4 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2 1.4 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.2 4.8 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.2 0.5 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.2 1.2 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.2 2.7 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.2 0.5 GO:0090327 negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.2 0.5 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.2 0.5 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.2 0.8 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.2 0.5 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) cell proliferation involved in heart valve development(GO:2000793)
0.1 1.0 GO:0035754 B cell chemotaxis(GO:0035754)
0.1 3.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.5 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.1 0.5 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.1 0.2 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.1 0.5 GO:0070269 pyroptosis(GO:0070269)
0.1 0.5 GO:0035470 positive regulation of vascular wound healing(GO:0035470) regulation of vascular wound healing(GO:0061043)
0.1 0.3 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
0.1 0.4 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.1 1.5 GO:1900746 regulation of vascular endothelial growth factor signaling pathway(GO:1900746)
0.1 0.3 GO:2000314 negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.1 1.7 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.1 0.6 GO:0009405 pathogenesis(GO:0009405)
0.1 1.9 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 0.3 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.1 1.6 GO:1901629 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688) regulation of presynaptic membrane organization(GO:1901629)
0.1 1.0 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 0.3 GO:1903463 regulation of mitotic cell cycle DNA replication(GO:1903463)
0.1 0.7 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.1 0.9 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.2 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.1 0.5 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.1 0.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430) GPI anchor release(GO:0006507)
0.1 1.6 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.1 0.2 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 1.1 GO:0071625 vocalization behavior(GO:0071625)
0.1 0.3 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 0.4 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 0.2 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1 0.5 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.1 0.6 GO:0042538 hyperosmotic salinity response(GO:0042538)
0.1 0.6 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 1.9 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 0.2 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 0.4 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 1.8 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.1 0.7 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.2 GO:0008594 photoreceptor cell morphogenesis(GO:0008594)
0.1 0.2 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.1 0.9 GO:0007379 segment specification(GO:0007379)
0.1 0.7 GO:0000729 DNA double-strand break processing(GO:0000729)
0.1 0.2 GO:0000733 DNA strand renaturation(GO:0000733)
0.1 0.4 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.6 GO:0097186 amelogenesis(GO:0097186)
0.0 0.1 GO:0002934 desmosome organization(GO:0002934)
0.0 1.7 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 1.0 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.5 GO:0015838 proline transport(GO:0015824) amino-acid betaine transport(GO:0015838)
0.0 1.8 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.4 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.5 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 2.3 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.9 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.1 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 0.2 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0 1.1 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 3.1 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.8 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.0 0.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.2 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.2 GO:0046864 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865) alveolar primary septum development(GO:0061143) paramesonephric duct development(GO:0061205)
0.0 0.3 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.8 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0 0.6 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.5 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.2 GO:0036089 cleavage furrow formation(GO:0036089)
0.0 0.4 GO:0046697 decidualization(GO:0046697)
0.0 0.8 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.1 GO:0019441 tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) quinolinate biosynthetic process(GO:0019805) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218) kynurenine metabolic process(GO:0070189)
0.0 0.1 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.6 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.3 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.2 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 1.5 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.7 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.1 GO:0060613 fat pad development(GO:0060613)
0.0 0.9 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.2 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.4 GO:0061157 mRNA destabilization(GO:0061157)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.3 GO:0042640 anagen(GO:0042640)
0.0 0.2 GO:0015809 arginine transport(GO:0015809)
0.0 0.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.2 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.0 0.3 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.3 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.2 GO:0046688 response to copper ion(GO:0046688)
0.0 0.4 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.6 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.1 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.5 GO:0030488 tRNA methylation(GO:0030488)
0.0 1.0 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.9 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.1 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.1 GO:1904667 negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.0 0.2 GO:0007602 phototransduction(GO:0007602)
0.0 0.3 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.1 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.5 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.6 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.0 0.1 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.3 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 0.5 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.4 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 0.3 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.8 2.4 GO:0005588 collagen type V trimer(GO:0005588)
0.8 2.3 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.4 1.9 GO:0070820 tertiary granule(GO:0070820)
0.3 1.7 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.2 2.1 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.2 0.6 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.2 0.7 GO:0008623 CHRAC(GO:0008623)
0.2 1.1 GO:0097513 myosin II filament(GO:0097513)
0.2 0.2 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.1 0.6 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 2.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 1.4 GO:0098644 complex of collagen trimers(GO:0098644)
0.1 0.5 GO:0061702 inflammasome complex(GO:0061702)
0.1 1.0 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.8 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 1.9 GO:0032279 asymmetric synapse(GO:0032279)
0.1 0.5 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.5 GO:0070531 BRCA1-A complex(GO:0070531)
0.1 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.5 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.2 GO:0072534 perineuronal net(GO:0072534)
0.1 0.3 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 2.5 GO:0016235 aggresome(GO:0016235)
0.0 1.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.6 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.5 GO:0070938 contractile ring(GO:0070938)
0.0 0.2 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.4 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 3.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.8 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.0 2.1 GO:0070469 respiratory chain(GO:0070469)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.4 GO:1990635 proximal dendrite(GO:1990635)
0.0 1.0 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.4 GO:0045120 pronucleus(GO:0045120)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)
0.0 0.2 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.6 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.7 GO:0008180 COP9 signalosome(GO:0008180)
0.0 3.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.3 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.5 GO:0005657 replication fork(GO:0005657)
0.0 1.0 GO:0030175 filopodium(GO:0030175)
0.0 0.1 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.8 GO:0050436 microfibril binding(GO:0050436)
0.7 2.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.6 2.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.4 2.8 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.4 1.5 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3 2.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.3 1.0 GO:0005110 frizzled-2 binding(GO:0005110)
0.2 0.9 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.2 0.7 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.2 0.6 GO:0036361 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.2 1.8 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.2 0.7 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.2 1.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.2 1.0 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.2 1.1 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.2 0.5 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.2 0.9 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.1 0.4 GO:0001129 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.1 0.6 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 0.6 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 1.0 GO:0070697 activin receptor binding(GO:0070697)
0.1 2.8 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 2.2 GO:0017166 vinculin binding(GO:0017166)
0.1 0.4 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 0.4 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.1 0.8 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.1 0.5 GO:0004966 galanin receptor activity(GO:0004966)
0.1 0.6 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 0.4 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.1 0.8 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.8 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 0.3 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 0.9 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.6 GO:1901612 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.1 0.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.5 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.4 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.3 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.1 0.9 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.1 1.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.2 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 2.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.5 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 1.6 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 0.3 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.1 1.8 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.4 GO:0019211 phosphatase activator activity(GO:0019211)
0.1 0.5 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 0.6 GO:0050733 RS domain binding(GO:0050733)
0.1 0.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 0.3 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.4 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 0.9 GO:0050811 GABA-A receptor activity(GO:0004890) GABA receptor binding(GO:0050811)
0.0 1.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 2.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.1 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.6 GO:0015643 toxic substance binding(GO:0015643)
0.0 1.9 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.5 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.7 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 1.5 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.2 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.2 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.4 GO:0032564 dATP binding(GO:0032564)
0.0 1.9 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.4 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 3.5 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.9 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 2.3 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.4 GO:0070513 death domain binding(GO:0070513)
0.0 0.2 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.2 GO:0000150 recombinase activity(GO:0000150)
0.0 0.2 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 1.4 GO:0005518 collagen binding(GO:0005518)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 2.1 GO:0005178 integrin binding(GO:0005178)
0.0 1.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.5 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.1 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 0.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.2 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.2 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.5 GO:0031690 adrenergic receptor binding(GO:0031690)
0.0 0.6 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0004954 icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)
0.0 0.0 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.1 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.3 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.4 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.5 GO:0030332 cyclin binding(GO:0030332)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.2 NABA_COLLAGENS Genes encoding collagen proteins
0.1 1.1 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.1 2.2 PID_ARF6_PATHWAY Arf6 signaling events
0.0 2.2 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 1.4 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.6 PID_ATM_PATHWAY ATM pathway
0.0 1.0 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.9 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 1.8 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.0 4.4 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.4 PID_BMP_PATHWAY BMP receptor signaling
0.0 0.6 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 1.0 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.5 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.4 PID_FOXO_PATHWAY FoxO family signaling
0.0 0.2 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 0.5 PID_VEGFR1_PATHWAY VEGFR1 specific signals
0.0 1.3 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 0.6 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.8 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.2 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 0.4 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.6 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.7 PID_TNF_PATHWAY TNF receptor signaling pathway
0.0 1.1 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 0.2 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.4 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 1.4 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.0 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 1.0 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.1 1.4 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.1 4.3 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 2.2 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.9 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 2.1 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 2.8 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 2.0 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 1.4 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 0.9 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.9 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.2 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 1.1 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.1 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.5 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.5 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.3 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.2 REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.5 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.7 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.4 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.8 REACTOME_ENOS_ACTIVATION_AND_REGULATION Genes involved in eNOS activation and regulation
0.0 0.3 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.6 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.5 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.0 0.4 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.5 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.2 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.2 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 0.2 REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.4 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.6 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.2 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.1 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.6 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.0 0.6 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.1 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism