Motif ID: Atf5

Z-value: 0.679


Transcription factors associated with Atf5:

Gene SymbolEntrez IDGene Name
Atf5 ENSMUSG00000038539.8 Atf5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Atf5mm10_v2_chr7_-_44815658_44815682-0.391.1e-02Click!


Activity profile for motif Atf5.

activity profile for motif Atf5


Sorted Z-values histogram for motif Atf5

Sorted Z-values for motif Atf5



Network of associatons between targets according to the STRING database.



First level regulatory network of Atf5

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_56971762 3.369 ENSMUST00000114415.3
Satb2
special AT-rich sequence binding protein 2
chrX_+_41401128 3.159 ENSMUST00000115103.2
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr16_+_43503607 3.051 ENSMUST00000126100.1
ENSMUST00000123047.1
ENSMUST00000156981.1
Zbtb20


zinc finger and BTB domain containing 20


chrX_+_41401304 2.733 ENSMUST00000076349.5
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr1_-_22805994 2.524 ENSMUST00000097808.4
Rims1
regulating synaptic membrane exocytosis 1
chr4_-_82705735 2.367 ENSMUST00000155821.1
Nfib
nuclear factor I/B
chr1_-_158356258 2.350 ENSMUST00000004133.8
Brinp2
bone morphogenic protein/retinoic acid inducible neural-specific 2
chr16_+_38089001 2.230 ENSMUST00000023507.6
Gsk3b
glycogen synthase kinase 3 beta
chr18_+_64254359 2.151 ENSMUST00000025477.7
St8sia3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chrX_+_41401476 2.092 ENSMUST00000165288.1
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr13_+_104287855 1.901 ENSMUST00000065766.6
Adamts6
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 6
chr15_-_102529025 1.869 ENSMUST00000096143.1
Atf7
activating transcription factor 7
chr18_-_23041641 1.714 ENSMUST00000097651.3
Nol4
nucleolar protein 4
chr15_-_79164477 1.679 ENSMUST00000040019.4
Sox10
SRY-box containing gene 10
chrX_-_41911877 1.550 ENSMUST00000047037.8
Thoc2
THO complex 2
chr4_-_91376433 1.543 ENSMUST00000107109.2
ENSMUST00000107111.2
ENSMUST00000107120.1
Elavl2


ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)


chr8_+_54954728 1.522 ENSMUST00000033915.7
Gpm6a
glycoprotein m6a
chr10_+_115384951 1.398 ENSMUST00000036044.8
Zfc3h1
zinc finger, C3H1-type containing
chr10_+_90071095 1.358 ENSMUST00000183109.1
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr4_-_11322109 1.352 ENSMUST00000084892.5
ENSMUST00000128024.1
Dpy19l4

dpy-19-like 4 (C. elegans)

chr1_-_157256682 1.326 ENSMUST00000134543.1
Rasal2
RAS protein activator like 2
chr1_-_64121389 1.300 ENSMUST00000055001.3
Klf7
Kruppel-like factor 7 (ubiquitous)
chr14_+_54936456 1.293 ENSMUST00000037814.6
Cmtm5
CKLF-like MARVEL transmembrane domain containing 5
chr11_+_83302817 1.264 ENSMUST00000142680.1
Ap2b1
adaptor-related protein complex 2, beta 1 subunit
chr4_+_141278433 1.261 ENSMUST00000142429.1
Gm13056
predicted gene 13056
chr3_+_7366598 1.242 ENSMUST00000028999.6
Pkia
protein kinase inhibitor, alpha
chr11_+_83302641 1.238 ENSMUST00000176430.1
ENSMUST00000065692.7
Ap2b1

adaptor-related protein complex 2, beta 1 subunit

chr8_-_95807458 1.211 ENSMUST00000098473.4
ENSMUST00000068452.8
Cnot1

CCR4-NOT transcription complex, subunit 1

chr3_+_114030532 1.199 ENSMUST00000123619.1
ENSMUST00000092155.5
Col11a1

collagen, type XI, alpha 1

chrX_+_166344692 1.189 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
Gpm6b





glycoprotein m6b





chr19_-_4698315 1.180 ENSMUST00000096325.3
Gm960
predicted gene 960
chr4_+_86748526 1.154 ENSMUST00000082026.7
ENSMUST00000045512.8
Dennd4c

DENN/MADD domain containing 4C

chr19_-_29805989 1.117 ENSMUST00000177155.1
ENSMUST00000059484.7
9930021J03Rik

RIKEN cDNA 9930021J03 gene

chr14_-_101609033 1.108 ENSMUST00000161991.1
ENSMUST00000100340.3
Tbc1d4

TBC1 domain family, member 4

chr7_+_25268387 1.080 ENSMUST00000169392.1
Cic
capicua homolog (Drosophila)
chr18_+_35562158 1.079 ENSMUST00000166793.1
Matr3
matrin 3
chr19_-_46327121 1.066 ENSMUST00000041391.4
ENSMUST00000096029.5
Psd

pleckstrin and Sec7 domain containing

chr4_+_133011506 1.058 ENSMUST00000105915.1
ENSMUST00000105916.1
Ahdc1

AT hook, DNA binding motif, containing 1

chr6_+_33249085 1.045 ENSMUST00000052266.8
ENSMUST00000090381.4
ENSMUST00000115080.1
Exoc4


exocyst complex component 4


chr5_+_19907774 1.039 ENSMUST00000115267.2
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr14_+_64652524 1.023 ENSMUST00000100473.4
Kif13b
kinesin family member 13B
chr1_-_64121456 1.005 ENSMUST00000142009.1
ENSMUST00000114086.1
Klf7

Kruppel-like factor 7 (ubiquitous)

chr19_+_27217357 0.970 ENSMUST00000047645.6
ENSMUST00000167487.1
Vldlr

very low density lipoprotein receptor

chr3_+_103914099 0.968 ENSMUST00000051139.6
ENSMUST00000068879.4
Rsbn1

rosbin, round spermatid basic protein 1

chr11_+_53433299 0.867 ENSMUST00000018382.6
Gdf9
growth differentiation factor 9
chr15_+_12117848 0.841 ENSMUST00000128475.1
ENSMUST00000134277.1
Zfr

zinc finger RNA binding protein

chr3_-_18243289 0.838 ENSMUST00000035625.6
Cyp7b1
cytochrome P450, family 7, subfamily b, polypeptide 1
chr16_-_16560201 0.835 ENSMUST00000162045.1
ENSMUST00000162124.1
ENSMUST00000161861.1
Fgd4


FYVE, RhoGEF and PH domain containing 4


chr19_+_27217011 0.830 ENSMUST00000164746.1
ENSMUST00000172302.1
Vldlr

very low density lipoprotein receptor

chr17_-_46031813 0.816 ENSMUST00000024747.7
Vegfa
vascular endothelial growth factor A
chr14_-_12823031 0.815 ENSMUST00000067491.6
ENSMUST00000177814.1
ENSMUST00000112658.1
ENSMUST00000112657.2
Cadps



Ca2+-dependent secretion activator



chr10_+_95940663 0.806 ENSMUST00000053484.6
Eea1
early endosome antigen 1
chr16_-_10447340 0.763 ENSMUST00000051118.6
Tvp23a
trans-golgi network vesicle protein 23A
chr3_-_94436574 0.758 ENSMUST00000029787.4
Oaz3
ornithine decarboxylase antizyme 3
chr12_+_89812467 0.753 ENSMUST00000110133.2
ENSMUST00000110130.2
Nrxn3

neurexin III

chr6_-_137571007 0.743 ENSMUST00000100841.2
Eps8
epidermal growth factor receptor pathway substrate 8
chr11_-_120630126 0.725 ENSMUST00000106180.1
Mafg
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr4_-_127970951 0.724 ENSMUST00000030614.2
CK137956
cDNA sequence CK137956
chr5_+_19907502 0.683 ENSMUST00000101558.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr8_+_105348163 0.658 ENSMUST00000073149.5
Slc9a5
solute carrier family 9 (sodium/hydrogen exchanger), member 5
chr7_+_51621830 0.633 ENSMUST00000032710.5
Slc17a6
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
chr11_-_83302586 0.622 ENSMUST00000176374.1
Pex12
peroxisomal biogenesis factor 12
chr4_-_8239034 0.605 ENSMUST00000066674.7
Car8
carbonic anhydrase 8
chr9_+_32116040 0.582 ENSMUST00000174641.1
Arhgap32
Rho GTPase activating protein 32
chr11_-_46166397 0.581 ENSMUST00000020679.2
Nipal4
NIPA-like domain containing 4
chr2_+_124610573 0.580 ENSMUST00000103239.3
ENSMUST00000103240.2
Sema6d

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D

chr14_+_69029289 0.538 ENSMUST00000014957.8
Stc1
stanniocalcin 1
chr18_+_65581704 0.524 ENSMUST00000182979.1
Zfp532
zinc finger protein 532
chr11_-_69369377 0.523 ENSMUST00000092971.6
ENSMUST00000108661.1
Chd3

chromodomain helicase DNA binding protein 3

chr9_+_54980880 0.506 ENSMUST00000093844.3
Chrna5
cholinergic receptor, nicotinic, alpha polypeptide 5
chr19_-_42202150 0.504 ENSMUST00000018966.7
Sfrp5
secreted frizzled-related sequence protein 5
chr9_+_78113275 0.496 ENSMUST00000009972.5
ENSMUST00000117330.1
ENSMUST00000044551.7
Ick


intestinal cell kinase


chr5_+_149678224 0.489 ENSMUST00000100404.3
B3galtl
beta 1,3-galactosyltransferase-like
chr12_+_3365108 0.477 ENSMUST00000020999.5
Kif3c
kinesin family member 3C
chr14_-_124677089 0.451 ENSMUST00000095529.3
Fgf14
fibroblast growth factor 14
chr2_+_172393794 0.450 ENSMUST00000099061.2
ENSMUST00000103073.2
Cass4

Cas scaffolding protein family member 4

chr4_+_54947976 0.446 ENSMUST00000098070.3
Zfp462
zinc finger protein 462
chr1_-_45503282 0.421 ENSMUST00000086430.4
Col5a2
collagen, type V, alpha 2
chr18_+_65582239 0.400 ENSMUST00000182684.1
Zfp532
zinc finger protein 532
chr16_-_16560046 0.386 ENSMUST00000172181.2
Fgd4
FYVE, RhoGEF and PH domain containing 4
chr1_-_135167606 0.385 ENSMUST00000027682.8
Gpr37l1
G protein-coupled receptor 37-like 1
chr10_-_53699343 0.383 ENSMUST00000163761.1
Fam184a
family with sequence similarity 184, member A
chr5_-_100798468 0.380 ENSMUST00000133845.1
ENSMUST00000044684.7
Helq

helicase, POLQ-like

chr5_+_32611171 0.374 ENSMUST00000072311.6
ENSMUST00000168707.2
Yes1

Yamaguchi sarcoma viral (v-yes) oncogene homolog 1

chr1_+_74375203 0.372 ENSMUST00000027368.5
Slc11a1
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
chr4_-_43046196 0.367 ENSMUST00000036462.5
Fam214b
family with sequence similarity 214, member B
chr1_+_59516264 0.365 ENSMUST00000114243.1
Gm973
predicted gene 973
chr19_-_19001099 0.348 ENSMUST00000040153.8
ENSMUST00000112828.1
Rorb

RAR-related orphan receptor beta

chr16_-_46010212 0.342 ENSMUST00000130481.1
Plcxd2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr19_-_37178011 0.335 ENSMUST00000133988.1
Cpeb3
cytoplasmic polyadenylation element binding protein 3
chr14_+_18271122 0.329 ENSMUST00000132374.1
ENSMUST00000133460.1
Nkiras1

NFKB inhibitor interacting Ras-like protein 1

chr14_+_12284198 0.327 ENSMUST00000112669.3
ENSMUST00000163392.1
3830406C13Rik

RIKEN cDNA 3830406C13 gene

chr15_-_77153772 0.320 ENSMUST00000166610.1
ENSMUST00000111581.2
Rbfox2

RNA binding protein, fox-1 homolog (C. elegans) 2

chr11_+_98741805 0.310 ENSMUST00000064187.5
Thra
thyroid hormone receptor alpha
chr7_-_25390098 0.303 ENSMUST00000054301.7
Lipe
lipase, hormone sensitive
chrX_+_42151002 0.301 ENSMUST00000123245.1
Stag2
stromal antigen 2
chr15_+_41830921 0.297 ENSMUST00000166917.1
Oxr1
oxidation resistance 1
chr7_+_29134854 0.282 ENSMUST00000161522.1
ENSMUST00000159975.1
ENSMUST00000032811.5
ENSMUST00000094617.4
Rasgrp4



RAS guanyl releasing protein 4



chr18_+_65582390 0.267 ENSMUST00000169679.1
ENSMUST00000183326.1
Zfp532

zinc finger protein 532

chr10_-_14718191 0.258 ENSMUST00000020016.4
Gje1
gap junction protein, epsilon 1
chr19_+_45363734 0.240 ENSMUST00000065601.5
ENSMUST00000111936.2
Btrc

beta-transducin repeat containing protein

chr11_+_98741871 0.224 ENSMUST00000103139.4
Thra
thyroid hormone receptor alpha
chr17_+_35220834 0.203 ENSMUST00000118793.1
Gm16181
predicted gene 16181
chr19_+_6497772 0.181 ENSMUST00000113458.1
ENSMUST00000113459.1
Nrxn2

neurexin II

chr8_-_83694004 0.165 ENSMUST00000144258.1
Pkn1
protein kinase N1
chrX_+_42150672 0.163 ENSMUST00000069619.7
Stag2
stromal antigen 2
chr9_-_57606234 0.158 ENSMUST00000045068.8
Cplx3
complexin 3
chr7_-_4996044 0.151 ENSMUST00000162502.1
Zfp579
zinc finger protein 579
chr2_-_120539852 0.140 ENSMUST00000171215.1
Zfp106
zinc finger protein 106
chr4_-_119415494 0.124 ENSMUST00000063642.2
Ccdc30
coiled-coil domain containing 30
chr11_+_87578384 0.111 ENSMUST00000107962.1
ENSMUST00000122067.1
Sept4

septin 4

chr4_+_11758147 0.109 ENSMUST00000029871.5
ENSMUST00000108303.1
Cdh17

cadherin 17

chr5_+_147188678 0.102 ENSMUST00000065382.5
Gsx1
GS homeobox 1
chr17_+_35866606 0.100 ENSMUST00000113814.4
Ppp1r18
protein phosphatase 1, regulatory subunit 18
chr10_-_63244135 0.097 ENSMUST00000054837.3
1700120B22Rik
RIKEN cDNA 1700120B22 gene
chr6_-_97205549 0.094 ENSMUST00000164744.1
ENSMUST00000089287.5
Uba3

ubiquitin-like modifier activating enzyme 3

chrX_-_20931520 0.083 ENSMUST00000001156.7
Cfp
complement factor properdin
chr10_+_79974409 0.062 ENSMUST00000131816.1
Grin3b
glutamate receptor, ionotropic, NMDA3B
chr5_-_115341142 0.056 ENSMUST00000139167.1
Gatc
glutamyl-tRNA(Gln) amidotransferase, subunit C homolog (bacterial)
chrX_+_99003224 0.048 ENSMUST00000149999.1
Stard8
START domain containing 8
chr1_-_37536232 0.048 ENSMUST00000042161.8
Mgat4a
mannoside acetylglucosaminyltransferase 4, isoenzyme A
chr2_+_178141920 0.035 ENSMUST00000103066.3
Phactr3
phosphatase and actin regulator 3
chr11_-_20112876 0.012 ENSMUST00000000137.7
Actr2
ARP2 actin-related protein 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.6 2.5 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.6 2.4 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.5 2.2 GO:1990743 protein sialylation(GO:1990743)
0.5 1.4 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.4 1.8 GO:0034436 glycoprotein transport(GO:0034436)
0.3 1.7 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.3 1.2 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.3 2.5 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.3 0.8 GO:1902336 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336)
0.2 1.7 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.2 0.4 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 0.8 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.2 1.2 GO:0035989 tendon development(GO:0035989)
0.2 0.8 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.2 0.7 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.2 0.5 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.2 1.0 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.2 0.9 GO:0042701 progesterone secretion(GO:0042701)
0.2 1.5 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.2 1.2 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.2 8.0 GO:0001919 regulation of receptor recycling(GO:0001919)
0.2 0.5 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.2 2.6 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 1.2 GO:0030035 microspike assembly(GO:0030035)
0.1 1.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 0.4 GO:0032632 interleukin-3 production(GO:0032632)
0.1 1.1 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.1 0.8 GO:0035754 B cell chemotaxis(GO:0035754)
0.1 1.4 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 0.3 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.1 1.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.3 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.5 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.1 0.5 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.1 3.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.6 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1 0.5 GO:0060536 cartilage morphogenesis(GO:0060536)
0.1 0.7 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.3 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 3.1 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 0.5 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 1.3 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.8 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.5 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 1.5 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.8 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 1.1 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.4 GO:0021940 positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.0 0.2 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.6 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.6 GO:0015693 magnesium ion transport(GO:0015693)
0.0 1.1 GO:0003170 heart valve development(GO:0003170)
0.0 1.9 GO:0060976 coronary vasculature development(GO:0060976)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0007113 endomitotic cell cycle(GO:0007113)
0.0 1.3 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.0 0.6 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.2 GO:0042297 vocal learning(GO:0042297) imitative learning(GO:0098596)
0.0 0.1 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.6 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 2.3 GO:0048813 dendrite morphogenesis(GO:0048813)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 8.0 GO:0043083 synaptic cleft(GO:0043083)
0.5 2.5 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.2 1.7 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.2 2.2 GO:1990909 Wnt signalosome(GO:1990909)
0.2 1.7 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 0.6 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.2 1.5 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2 1.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 1.8 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.1 0.4 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.8 GO:0044308 axonal spine(GO:0044308)
0.1 1.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 2.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 1.0 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.4 GO:0030670 phagocytic vesicle membrane(GO:0030670) tertiary granule(GO:0070820)
0.1 1.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 2.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 0.8 GO:0031045 dense core granule(GO:0031045)
0.0 0.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.5 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 1.0 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.5 GO:0097542 ciliary tip(GO:0097542)
0.0 3.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.4 GO:1904949 ATPase complex(GO:1904949)
0.0 1.4 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.6 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.3 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 2.7 GO:0030175 filopodium(GO:0030175)
0.0 0.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.9 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.1 GO:0097227 sperm annulus(GO:0097227)
0.0 1.1 GO:0032587 ruffle membrane(GO:0032587)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 8.0 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.6 1.8 GO:0034437 very-low-density lipoprotein particle binding(GO:0034189) glycoprotein transporter activity(GO:0034437)
0.4 2.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.3 1.2 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.3 1.7 GO:0070699 type II activin receptor binding(GO:0070699)
0.3 0.8 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.2 3.5 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.2 0.8 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.2 0.5 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.1 0.3 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 0.8 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 1.0 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.1 0.4 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.1 2.4 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 1.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.3 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 1.4 GO:0000030 mannosyltransferase activity(GO:0000030)
0.1 0.2 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 1.0 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 1.1 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 2.5 GO:0030276 clathrin binding(GO:0030276)
0.0 1.9 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.6 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.0 0.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 3.6 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.9 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.9 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 1.6 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.3 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 1.5 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.8 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.7 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.5 GO:0005179 hormone activity(GO:0005179)
0.0 0.8 GO:0005125 cytokine activity(GO:0005125)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.3 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.1 0.8 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 1.8 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 2.1 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 1.6 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 1.0 PID_ARF6_PATHWAY Arf6 signaling events
0.0 1.9 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 1.0 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 3.7 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 0.4 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 0.5 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.9 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.7 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.7 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 10.5 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.3 2.5 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 0.8 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.1 2.2 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.1 2.3 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 0.8 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 0.5 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 1.7 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 1.0 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.4 REACTOME_PECAM1_INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.6 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.5 REACTOME_KINESINS Genes involved in Kinesins
0.0 0.4 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 1.2 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.8 REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.3 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.9 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.3 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides