Motif ID: Tbp

Z-value: 2.979


Transcription factors associated with Tbp:

Gene SymbolEntrez IDGene Name
Tbp ENSMUSG00000014767.10 Tbp

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tbpmm10_v2_chr17_+_15499888_15499960-0.791.1e-09Click!


Activity profile for motif Tbp.

activity profile for motif Tbp


Sorted Z-values histogram for motif Tbp

Sorted Z-values for motif Tbp



Network of associatons between targets according to the STRING database.



First level regulatory network of Tbp

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_87948666 32.780 ENSMUST00000005019.5
Crabp2
cellular retinoic acid binding protein II
chr7_-_103853199 27.205 ENSMUST00000033229.3
Hbb-y
hemoglobin Y, beta-like embryonic chain
chr3_-_145649970 24.001 ENSMUST00000029846.3
Cyr61
cysteine rich protein 61
chr8_+_94179089 20.671 ENSMUST00000034215.6
Mt1
metallothionein 1
chr13_+_21717626 20.486 ENSMUST00000091754.2
Hist1h3h
histone cluster 1, H3h
chr2_+_13573927 14.543 ENSMUST00000141365.1
ENSMUST00000028062.2
Vim

vimentin

chr13_+_23581563 14.522 ENSMUST00000102968.1
Hist1h4d
histone cluster 1, H4d
chrX_-_162159717 14.358 ENSMUST00000087085.3
Nhs
Nance-Horan syndrome (human)
chr4_+_136143497 14.288 ENSMUST00000008016.2
Id3
inhibitor of DNA binding 3
chr13_+_23575753 14.028 ENSMUST00000105105.1
Hist1h3d
histone cluster 1, H3d
chr13_+_51846673 13.587 ENSMUST00000021903.2
Gadd45g
growth arrest and DNA-damage-inducible 45 gamma
chr1_+_109993982 13.548 ENSMUST00000027542.6
Cdh7
cadherin 7, type 2
chr7_-_142899985 13.487 ENSMUST00000000219.3
Th
tyrosine hydroxylase
chr5_-_77115145 13.186 ENSMUST00000081964.5
Hopx
HOP homeobox
chr13_+_23752267 13.166 ENSMUST00000091703.2
Hist1h3b
histone cluster 1, H3b
chr13_-_21750505 12.747 ENSMUST00000102983.1
Hist1h4k
histone cluster 1, H4k
chr17_-_24251382 12.200 ENSMUST00000115390.3
Ccnf
cyclin F
chr13_-_21783391 12.002 ENSMUST00000099704.3
Hist1h3i
histone cluster 1, H3i
chr17_+_24720063 11.752 ENSMUST00000170715.1
ENSMUST00000054289.6
ENSMUST00000146867.1
Rps2


ribosomal protein S2


chr12_-_111672290 11.742 ENSMUST00000001304.7
Ckb
creatine kinase, brain
chr6_-_87981482 11.741 ENSMUST00000056403.5
H1fx
H1 histone family, member X
chr11_+_120949053 11.625 ENSMUST00000154187.1
ENSMUST00000100130.3
ENSMUST00000129473.1
ENSMUST00000168579.1
Slc16a3



solute carrier family 16 (monocarboxylic acid transporters), member 3



chr16_+_91225550 11.505 ENSMUST00000035608.8
Olig2
oligodendrocyte transcription factor 2
chr2_-_93957040 11.467 ENSMUST00000148314.2
Gm13889
predicted gene 13889
chr1_-_138842429 11.361 ENSMUST00000112026.2
ENSMUST00000019374.7
Lhx9

LIM homeobox protein 9

chr14_+_68083853 10.769 ENSMUST00000022639.7
Nefl
neurofilament, light polypeptide
chr10_+_88091070 10.572 ENSMUST00000048621.7
Pmch
pro-melanin-concentrating hormone
chr2_+_152736244 10.551 ENSMUST00000038368.8
ENSMUST00000109824.1
Id1

inhibitor of DNA binding 1

chr12_+_3954943 10.456 ENSMUST00000020990.5
Pomc
pro-opiomelanocortin-alpha
chr13_+_23544052 10.382 ENSMUST00000075558.2
Hist1h3f
histone cluster 1, H3f
chr13_-_23745511 10.219 ENSMUST00000091752.2
Hist1h3c
histone cluster 1, H3c
chr13_+_113035111 10.185 ENSMUST00000180543.1
ENSMUST00000181568.1
ENSMUST00000109244.2
ENSMUST00000181117.1
ENSMUST00000181741.1
Cdc20b




cell division cycle 20B




chr18_+_34625009 10.133 ENSMUST00000166044.1
Kif20a
kinesin family member 20A
chr7_-_4812351 10.008 ENSMUST00000079496.7
Ube2s
ubiquitin-conjugating enzyme E2S
chr2_+_119618717 9.970 ENSMUST00000028771.7
Nusap1
nucleolar and spindle associated protein 1
chr4_+_116685859 9.896 ENSMUST00000129315.1
ENSMUST00000106470.1
Prdx1

peroxiredoxin 1

chr13_-_21780616 9.747 ENSMUST00000080511.2
Hist1h1b
histone cluster 1, H1b
chr1_-_171196229 9.535 ENSMUST00000111332.1
Pcp4l1
Purkinje cell protein 4-like 1
chr4_+_116685544 9.363 ENSMUST00000135573.1
ENSMUST00000151129.1
Prdx1

peroxiredoxin 1

chr11_-_99024179 9.349 ENSMUST00000068031.7
Top2a
topoisomerase (DNA) II alpha
chr6_+_4747306 9.226 ENSMUST00000175823.1
ENSMUST00000176204.1
ENSMUST00000166678.1
Peg10


paternally expressed 10


chr2_-_119618455 8.981 ENSMUST00000123818.1
Oip5
Opa interacting protein 5
chr13_-_23622502 8.680 ENSMUST00000062045.2
Hist1h1e
histone cluster 1, H1e
chr13_+_23684192 8.546 ENSMUST00000018246.4
Hist1h2bc
histone cluster 1, H2bc
chr19_-_53589067 8.524 ENSMUST00000095978.3
Nutf2-ps1
nuclear transport factor 2, pseudogene 1
chr2_+_91256144 8.403 ENSMUST00000154959.1
ENSMUST00000059566.4
Pacsin3

protein kinase C and casein kinase substrate in neurons 3

chr7_+_30553263 8.303 ENSMUST00000044048.7
Hspb6
heat shock protein, alpha-crystallin-related, B6
chr18_+_34624621 8.255 ENSMUST00000167161.1
Kif20a
kinesin family member 20A
chr8_+_12395287 8.242 ENSMUST00000180353.1
Sox1
SRY-box containing gene 1
chr17_-_34000257 8.146 ENSMUST00000087189.6
ENSMUST00000173075.1
ENSMUST00000172760.1
ENSMUST00000172912.1
ENSMUST00000025181.10
H2-K1




histocompatibility 2, K1, K region




chr13_-_21501418 8.106 ENSMUST00000044043.2
Gm11273
predicted gene 11273
chr13_-_23762378 8.082 ENSMUST00000091701.2
Hist1h3a
histone cluster 1, H3a
chr13_-_21716143 8.027 ENSMUST00000091756.1
Hist1h2bl
histone cluster 1, H2bl
chr9_+_95637601 7.890 ENSMUST00000015498.8
Pcolce2
procollagen C-endopeptidase enhancer 2
chr10_-_88605017 7.812 ENSMUST00000119185.1
ENSMUST00000121629.1
Mybpc1

myosin binding protein C, slow-type

chr13_+_23763660 7.788 ENSMUST00000055770.1
Hist1h1a
histone cluster 1, H1a
chr2_+_91255954 7.570 ENSMUST00000134699.1
Pacsin3
protein kinase C and casein kinase substrate in neurons 3
chr14_+_67745229 7.437 ENSMUST00000111095.2
Gnrh1
gonadotropin releasing hormone 1
chr2_-_164857542 7.428 ENSMUST00000109316.1
ENSMUST00000156255.1
ENSMUST00000128110.1
ENSMUST00000109317.3
Pltp



phospholipid transfer protein



chr2_+_25180737 7.428 ENSMUST00000104999.2
Nrarp
Notch-regulated ankyrin repeat protein
chr13_-_99900645 7.392 ENSMUST00000022150.6
Cartpt
CART prepropeptide
chr13_+_23531044 7.257 ENSMUST00000102972.3
Hist1h4h
histone cluster 1, H4h
chr6_-_125165576 7.178 ENSMUST00000183272.1
ENSMUST00000182052.1
ENSMUST00000182277.1
Gapdh


glyceraldehyde-3-phosphate dehydrogenase


chr4_-_132353605 7.151 ENSMUST00000155129.1
Rcc1
regulator of chromosome condensation 1
chr6_-_125165707 7.150 ENSMUST00000118875.1
Gapdh
glyceraldehyde-3-phosphate dehydrogenase
chr11_-_33163072 7.099 ENSMUST00000093201.6
ENSMUST00000101375.4
ENSMUST00000109354.3
ENSMUST00000075641.3
Npm1



nucleophosmin 1



chr10_-_40302186 7.041 ENSMUST00000099945.4
Amd1
S-adenosylmethionine decarboxylase 1
chr17_+_23726336 6.933 ENSMUST00000024701.7
Pkmyt1
protein kinase, membrane associated tyrosine/threonine 1
chr5_-_99978914 6.882 ENSMUST00000112939.3
ENSMUST00000171786.1
ENSMUST00000072750.6
ENSMUST00000019128.8
ENSMUST00000172361.1
Hnrnpd




heterogeneous nuclear ribonucleoprotein D




chr17_-_33824346 6.882 ENSMUST00000173879.1
ENSMUST00000166693.2
ENSMUST00000173019.1
ENSMUST00000087342.6
ENSMUST00000173844.1
Rps28




ribosomal protein S28




chr11_-_77725281 6.800 ENSMUST00000078623.4
Cryba1
crystallin, beta A1
chr2_-_25224653 6.595 ENSMUST00000043584.4
Tubb4b
tubulin, beta 4B class IVB
chr13_-_3893556 6.475 ENSMUST00000099946.4
Net1
neuroepithelial cell transforming gene 1
chr13_+_21716385 6.452 ENSMUST00000070124.3
Hist1h2ai
histone cluster 1, H2ai
chr7_-_137314394 6.310 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
Ebf3



early B cell factor 3



chr1_-_91413163 6.304 ENSMUST00000086851.1
Hes6
hairy and enhancer of split 6
chr2_-_51149100 6.270 ENSMUST00000154545.1
ENSMUST00000017288.2
Rnd3

Rho family GTPase 3

chr17_-_33955658 6.154 ENSMUST00000174609.2
ENSMUST00000008812.7
Rps18

ribosomal protein S18

chr13_+_23934434 6.100 ENSMUST00000072391.1
Hist1h2aa
histone cluster 1, H2aa
chr7_-_45459839 6.030 ENSMUST00000094434.4
Ftl1
ferritin light chain 1
chr8_-_84969412 5.992 ENSMUST00000147812.1
Rnaseh2a
ribonuclease H2, large subunit
chr19_+_8888880 5.904 ENSMUST00000096251.3
1810009A15Rik
RIKEN cDNA 1810009A15 gene
chr10_-_128626464 5.860 ENSMUST00000026420.5
Rps26
ribosomal protein S26
chr13_-_23934156 5.733 ENSMUST00000052776.2
Hist1h2ba
histone cluster 1, H2ba
chr1_-_134079114 5.658 ENSMUST00000020692.6
Btg2
B cell translocation gene 2, anti-proliferative
chr10_-_93589621 5.653 ENSMUST00000020203.6
Snrpf
small nuclear ribonucleoprotein polypeptide F
chr5_+_125389284 5.637 ENSMUST00000100700.2
Gm10382
predicted gene 10382
chr2_-_36104060 5.532 ENSMUST00000112961.3
ENSMUST00000112966.3
Lhx6

LIM homeobox protein 6

chr4_-_116627478 5.508 ENSMUST00000081182.4
ENSMUST00000030457.5
Nasp

nuclear autoantigenic sperm protein (histone-binding)

chr4_-_116627921 5.457 ENSMUST00000030456.7
Nasp
nuclear autoantigenic sperm protein (histone-binding)
chr11_-_31671863 5.427 ENSMUST00000058060.7
Bod1
biorientation of chromosomes in cell division 1
chr7_-_103843154 5.425 ENSMUST00000063957.4
Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr3_-_33082004 5.376 ENSMUST00000108225.3
Pex5l
peroxisomal biogenesis factor 5-like
chr1_+_134182404 5.360 ENSMUST00000153856.1
ENSMUST00000082060.3
ENSMUST00000133701.1
ENSMUST00000132873.1
Chi3l1



chitinase 3-like 1



chr13_+_21787461 5.213 ENSMUST00000110473.2
ENSMUST00000102982.1
Hist1h2bp

histone cluster 1, H2bp

chr8_+_58912257 5.206 ENSMUST00000160055.1
BC030500
cDNA sequence BC030500
chr13_-_21787218 5.201 ENSMUST00000091751.2
Hist1h2an
histone cluster 1, H2an
chr16_-_89508313 4.909 ENSMUST00000056118.2
Krtap7-1
keratin associated protein 7-1
chrX_+_36795642 4.901 ENSMUST00000016463.3
Slc25a5
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5
chr10_+_80826656 4.767 ENSMUST00000060987.8
ENSMUST00000177850.1
ENSMUST00000180036.1
ENSMUST00000179172.1
Oaz1



ornithine decarboxylase antizyme 1



chr14_+_69609068 4.751 ENSMUST00000022660.7
Loxl2
lysyl oxidase-like 2
chr4_-_133967296 4.669 ENSMUST00000105893.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr15_+_80255184 4.506 ENSMUST00000109605.3
Atf4
activating transcription factor 4
chr17_+_33824591 4.458 ENSMUST00000048249.6
Ndufa7
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7 (B14.5a)
chr6_-_136875794 4.402 ENSMUST00000032342.1
Mgp
matrix Gla protein
chrX_+_52791179 4.389 ENSMUST00000101588.1
Ccdc160
coiled-coil domain containing 160
chr13_-_23571151 4.379 ENSMUST00000102969.3
Hist1h2ae
histone cluster 1, H2ae
chr3_+_106113229 4.352 ENSMUST00000079132.5
ENSMUST00000139086.1
Chia

chitinase, acidic

chr8_-_61591130 4.337 ENSMUST00000135439.1
ENSMUST00000121200.1
Palld

palladin, cytoskeletal associated protein

chr1_+_134182150 4.331 ENSMUST00000156873.1
Chi3l1
chitinase 3-like 1
chr6_-_34317442 4.124 ENSMUST00000154655.1
ENSMUST00000102980.4
Akr1b3

aldo-keto reductase family 1, member B3 (aldose reductase)

chr15_-_60824942 4.112 ENSMUST00000100635.3
Fam84b
family with sequence similarity 84, member B
chr9_+_30942541 4.111 ENSMUST00000068135.6
Adamts8
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8
chrX_-_74353575 4.075 ENSMUST00000114152.1
ENSMUST00000114153.1
ENSMUST00000015433.3
Lage3


L antigen family, member 3


chr9_-_95815389 4.010 ENSMUST00000119760.1
Pls1
plastin 1 (I-isoform)
chr16_+_90220742 3.990 ENSMUST00000023707.9
Sod1
superoxide dismutase 1, soluble
chr5_+_135887905 3.980 ENSMUST00000005077.6
Hspb1
heat shock protein 1
chr9_+_21723576 3.903 ENSMUST00000034713.7
Ldlr
low density lipoprotein receptor
chr4_-_3835595 3.884 ENSMUST00000138502.1
Rps20
ribosomal protein S20
chr19_-_7039987 3.875 ENSMUST00000025918.7
Stip1
stress-induced phosphoprotein 1
chr7_+_28810886 3.818 ENSMUST00000038572.8
Hnrnpl
heterogeneous nuclear ribonucleoprotein L
chr13_-_23683941 3.818 ENSMUST00000171127.1
Hist1h2ac
histone cluster 1, H2ac
chr11_+_3289880 3.813 ENSMUST00000110043.1
ENSMUST00000094471.3
Patz1

POZ (BTB) and AT hook containing zinc finger 1

chrX_+_74270812 3.801 ENSMUST00000008826.7
ENSMUST00000151702.1
ENSMUST00000074085.5
ENSMUST00000135690.1
Rpl10



ribosomal protein L10



chr4_+_86930691 3.779 ENSMUST00000164590.1
Acer2
alkaline ceramidase 2
chr9_+_44334685 3.757 ENSMUST00000052686.2
H2afx
H2A histone family, member X
chrX_+_141475385 3.748 ENSMUST00000112931.1
ENSMUST00000112930.1
Col4a5

collagen, type IV, alpha 5

chr11_+_3289168 3.739 ENSMUST00000134089.1
Patz1
POZ (BTB) and AT hook containing zinc finger 1
chr8_+_84969767 3.729 ENSMUST00000109733.1
Prdx2
peroxiredoxin 2
chr6_-_24528013 3.713 ENSMUST00000023851.5
Ndufa5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr5_-_125390176 3.681 ENSMUST00000156249.1
Ubc
ubiquitin C
chr13_+_21735055 3.660 ENSMUST00000087714.4
Hist1h4j
histone cluster 1, H4j
chr11_-_100135928 3.637 ENSMUST00000107411.2
Krt15
keratin 15
chr18_+_4920509 3.625 ENSMUST00000126977.1
Svil
supervillin
chr6_-_72958097 3.609 ENSMUST00000114049.1
Tmsb10
thymosin, beta 10
chr11_+_6415443 3.605 ENSMUST00000132846.1
Ppia
peptidylprolyl isomerase A
chr8_+_84969587 3.600 ENSMUST00000109734.1
ENSMUST00000005292.8
Prdx2

peroxiredoxin 2

chr10_+_96616998 3.551 ENSMUST00000038377.7
Btg1
B cell translocation gene 1, anti-proliferative
chr17_+_29032664 3.524 ENSMUST00000130216.1
Srsf3
serine/arginine-rich splicing factor 3
chr6_+_135065651 3.517 ENSMUST00000050104.7
Gprc5a
G protein-coupled receptor, family C, group 5, member A
chr5_-_125389915 3.487 ENSMUST00000136312.1
Ubc
ubiquitin C
chr7_-_30612731 3.442 ENSMUST00000006476.4
Upk1a
uroplakin 1A
chr6_-_72958465 3.295 ENSMUST00000114050.1
Tmsb10
thymosin, beta 10
chr8_-_84969740 3.267 ENSMUST00000109736.2
ENSMUST00000140561.1
Rnaseh2a

ribonuclease H2, large subunit

chr11_+_94936224 3.146 ENSMUST00000001547.7
Col1a1
collagen, type I, alpha 1
chr15_-_101850778 3.033 ENSMUST00000023790.3
Krt1
keratin 1
chr17_-_84187939 2.996 ENSMUST00000060366.6
Zfp36l2
zinc finger protein 36, C3H type-like 2
chr4_+_123282778 2.992 ENSMUST00000106243.1
ENSMUST00000106241.1
ENSMUST00000080178.6
Pabpc4


poly(A) binding protein, cytoplasmic 4


chr2_-_86347764 2.977 ENSMUST00000099894.2
Olfr1055
olfactory receptor 1055
chr3_+_96268654 2.958 ENSMUST00000098843.2
Hist2h3b
histone cluster 2, H3b
chr11_+_120598421 2.951 ENSMUST00000026128.3
Anapc11
anaphase promoting complex subunit 11
chr13_+_23571382 2.941 ENSMUST00000079251.5
Hist1h2bg
histone cluster 1, H2bg
chr11_+_6560183 2.886 ENSMUST00000109722.2
Ccm2
cerebral cavernous malformation 2
chr6_-_112696604 2.843 ENSMUST00000113182.1
ENSMUST00000113180.1
ENSMUST00000068487.5
ENSMUST00000077088.4
Rad18



RAD18 homolog (S. cerevisiae)



chr5_+_135887988 2.821 ENSMUST00000111155.1
Hspb1
heat shock protein 1
chr19_+_9982694 2.815 ENSMUST00000025563.6
Fth1
ferritin heavy chain 1
chr11_+_120598532 2.815 ENSMUST00000093140.4
Anapc11
anaphase promoting complex subunit 11
chr9_-_78481724 2.696 ENSMUST00000042235.8
Eef1a1
eukaryotic translation elongation factor 1 alpha 1
chr3_+_142765216 2.678 ENSMUST00000029938.8
Gtf2b
general transcription factor IIB
chr6_+_72598475 2.675 ENSMUST00000070597.6
ENSMUST00000176364.1
ENSMUST00000176168.1
Retsat


retinol saturase (all trans retinol 13,14 reductase)


chr3_+_121723515 2.674 ENSMUST00000029771.8
F3
coagulation factor III
chr2_+_174415804 2.660 ENSMUST00000109075.1
ENSMUST00000016397.6
Nelfcd

negative elongation factor complex member C/D, Th1l

chr11_+_52232183 2.625 ENSMUST00000109072.1
Skp1a
S-phase kinase-associated protein 1A
chr15_+_10952332 2.553 ENSMUST00000022853.8
ENSMUST00000110523.1
C1qtnf3

C1q and tumor necrosis factor related protein 3

chr17_-_80207299 2.470 ENSMUST00000063417.9
Srsf7
serine/arginine-rich splicing factor 7
chr7_+_127983079 2.457 ENSMUST00000079045.2
B230325K18Rik
RIKEN cDNA B230325K18 gene
chr8_+_84969824 2.431 ENSMUST00000125893.1
Prdx2
peroxiredoxin 2
chr9_+_78175898 2.305 ENSMUST00000180974.1
C920006O11Rik
RIKEN cDNA C920006O11 gene
chr11_-_31671727 2.303 ENSMUST00000109415.1
Bod1
biorientation of chromosomes in cell division 1
chr2_+_167062934 2.239 ENSMUST00000125674.1
1500012F01Rik
RIKEN cDNA 1500012F01 gene
chr17_-_14694223 2.229 ENSMUST00000170872.1
Thbs2
thrombospondin 2
chr2_-_11603192 2.211 ENSMUST00000040314.5
Rbm17
RNA binding motif protein 17
chr15_-_80083374 2.211 ENSMUST00000081650.7
Rpl3
ribosomal protein L3
chr18_-_78123324 2.179 ENSMUST00000160292.1
ENSMUST00000091813.5
Slc14a1

solute carrier family 14 (urea transporter), member 1

chr14_-_56062307 2.170 ENSMUST00000043249.8
Mcpt4
mast cell protease 4
chr19_+_8723478 2.121 ENSMUST00000180819.1
ENSMUST00000181422.1
Snhg1

small nucleolar RNA host gene (non-protein coding) 1

chr13_+_23574381 2.099 ENSMUST00000090776.4
Hist1h2ad
histone cluster 1, H2ad
chr16_-_36455378 2.075 ENSMUST00000068182.2
Stfa3
stefin A3
chr1_+_164048214 2.012 ENSMUST00000027874.5
Sele
selectin, endothelial cell
chr14_+_65968483 1.974 ENSMUST00000022616.6
Clu
clusterin
chr9_-_88522876 1.972 ENSMUST00000180563.2
ENSMUST00000183030.1
ENSMUST00000182232.1
Snhg5


small nucleolar RNA host gene 5


chr4_+_127021311 1.954 ENSMUST00000030623.7
Sfpq
splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)
chr13_-_23574196 1.910 ENSMUST00000105106.1
Hist1h2bf
histone cluster 1, H2bf
chr11_+_62551676 1.902 ENSMUST00000136938.1
Ubb
ubiquitin B
chr8_+_4349588 1.888 ENSMUST00000110982.1
ENSMUST00000024004.7
Ccl25

chemokine (C-C motif) ligand 25

chr4_+_42629719 1.869 ENSMUST00000166898.2
Gm2564
predicted gene 2564
chr3_-_106167564 1.863 ENSMUST00000063062.8
Chi3l3
chitinase 3-like 3
chr1_+_87183310 1.779 ENSMUST00000044533.8
Prss56
protease, serine 56
chr11_+_46436925 1.779 ENSMUST00000152119.1
ENSMUST00000140027.1
ENSMUST00000020665.6
ENSMUST00000170928.1
ENSMUST00000109231.1
ENSMUST00000109232.3
ENSMUST00000128940.1
Med7






mediator complex subunit 7






chr8_+_11556061 1.761 ENSMUST00000054399.4
Ing1
inhibitor of growth family, member 1
chr5_+_115559505 1.732 ENSMUST00000156359.1
ENSMUST00000152976.1
Rplp0

ribosomal protein, large, P0

chr11_-_115514374 1.731 ENSMUST00000021083.6
Hn1
hematological and neurological expressed sequence 1
chr18_-_36766198 1.678 ENSMUST00000061522.7
Dnd1
dead end homolog 1 (zebrafish)
chr12_-_110696289 1.625 ENSMUST00000021698.6
Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr11_-_120713725 1.601 ENSMUST00000106154.1
ENSMUST00000106155.3
ENSMUST00000055424.6
ENSMUST00000026137.7
Stra13



stimulated by retinoic acid 13



chr9_+_108508005 1.551 ENSMUST00000006838.8
ENSMUST00000134939.1
Qars

glutaminyl-tRNA synthetase

chr4_+_120666562 1.491 ENSMUST00000094814.4
Cited4
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr10_+_79988584 1.474 ENSMUST00000004784.4
ENSMUST00000105374.1
Cnn2

calponin 2

chrM_+_7759 1.444 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr13_+_23555023 1.442 ENSMUST00000045301.6
Hist1h1d
histone cluster 1, H1d

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.5 32.6 GO:0015671 oxygen transport(GO:0015671)
4.8 24.0 GO:0060591 chondroblast differentiation(GO:0060591)
4.1 20.7 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
3.8 119.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
3.8 11.5 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
3.6 10.8 GO:0045110 intermediate filament bundle assembly(GO:0045110)
3.5 10.5 GO:0035934 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
3.5 13.9 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
3.4 13.5 GO:0042414 epinephrine metabolic process(GO:0042414)
3.3 10.0 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
2.9 14.5 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
2.6 10.6 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
2.5 32.8 GO:0042573 retinoic acid metabolic process(GO:0042573)
2.5 7.4 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
2.4 7.1 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448) rRNA export from nucleus(GO:0006407)
2.3 7.0 GO:0006597 spermine biosynthetic process(GO:0006597)
2.3 9.3 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
2.3 6.9 GO:1901355 response to rapamycin(GO:1901355)
2.3 11.4 GO:0035262 gonad morphogenesis(GO:0035262)
2.2 13.2 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
2.0 8.1 GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
2.0 11.7 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
1.9 11.6 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
1.9 7.4 GO:0033087 negative regulation of immature T cell proliferation(GO:0033087)
1.9 7.4 GO:0042360 vitamin E metabolic process(GO:0042360)
1.8 21.4 GO:0002227 innate immune response in mucosa(GO:0002227)
1.7 12.2 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
1.7 33.0 GO:0019430 removal of superoxide radicals(GO:0019430)
1.6 7.8 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
1.5 9.3 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
1.5 4.6 GO:0019401 alditol biosynthetic process(GO:0019401)
1.5 10.6 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
1.5 4.5 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
1.5 9.0 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
1.4 10.1 GO:0016584 nucleosome positioning(GO:0016584)
1.4 13.6 GO:0042095 interferon-gamma biosynthetic process(GO:0042095)
1.3 4.0 GO:0001951 intestinal D-glucose absorption(GO:0001951) terminal web assembly(GO:1902896)
1.3 3.9 GO:0043031 regulation of phosphatidylcholine catabolic process(GO:0010899) negative regulation of macrophage activation(GO:0043031) receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118) regulation of microglial cell activation(GO:1903978)
1.3 3.8 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
1.2 4.8 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
1.1 6.8 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
1.1 6.7 GO:2000210 positive regulation of anoikis(GO:2000210)
1.0 18.4 GO:0000920 cell separation after cytokinesis(GO:0000920)
1.0 11.8 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.9 5.5 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.9 2.7 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.8 5.7 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.8 5.4 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.7 2.2 GO:0071918 urea transmembrane transport(GO:0071918)
0.7 5.8 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.7 10.0 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.7 16.0 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.7 7.4 GO:0014807 regulation of somitogenesis(GO:0014807)
0.7 1.3 GO:0060558 regulation of calcidiol 1-monooxygenase activity(GO:0060558)
0.6 2.6 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.6 12.1 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.6 1.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.6 3.6 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.6 40.2 GO:0006334 nucleosome assembly(GO:0006334)
0.5 4.8 GO:0046688 response to copper ion(GO:0046688)
0.5 2.0 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.5 1.9 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.5 3.3 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.5 8.2 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.5 1.4 GO:0042713 sperm ejaculation(GO:0042713) negative regulation of gastric acid secretion(GO:0060455)
0.4 3.1 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.4 2.7 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.4 3.0 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.4 3.0 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.4 1.2 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.4 1.2 GO:1902022 ovarian follicle rupture(GO:0001543) angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998) regulation of blood vessel size by renin-angiotensin(GO:0002034) brain renin-angiotensin system(GO:0002035) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) regulation of activation of Janus kinase activity(GO:0010533) L-lysine transport(GO:1902022)
0.4 2.7 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.4 2.7 GO:0042572 retinol metabolic process(GO:0042572)
0.4 3.8 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.4 1.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.4 6.5 GO:0051451 myoblast migration(GO:0051451)
0.4 5.7 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.3 6.9 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.3 1.0 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.3 2.0 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.3 0.6 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
0.3 4.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.3 2.8 GO:0051984 positive regulation of chromosome segregation(GO:0051984)
0.3 0.9 GO:1903225 regulation of endodermal cell fate specification(GO:0042663) negative regulation of endodermal cell differentiation(GO:1903225)
0.3 32.6 GO:0006342 chromatin silencing(GO:0006342)
0.3 2.1 GO:0021886 female meiosis I(GO:0007144) hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.3 0.9 GO:2000510 positive regulation of dendritic cell chemotaxis(GO:2000510)
0.3 8.3 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.3 4.7 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.3 4.3 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.3 2.9 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.3 0.9 GO:0097026 myeloid dendritic cell chemotaxis(GO:0002408) dendritic cell dendrite assembly(GO:0097026) mature conventional dendritic cell differentiation(GO:0097029)
0.2 3.7 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.2 0.2 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.2 8.8 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.2 7.2 GO:0051290 protein heterotetramerization(GO:0051290)
0.2 6.0 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.2 8.3 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.2 14.4 GO:0002088 lens development in camera-type eye(GO:0002088)
0.2 3.6 GO:0034389 lipid particle organization(GO:0034389)
0.2 2.0 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.2 1.4 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.2 0.3 GO:2000501 natural killer cell chemotaxis(GO:0035747) negative regulation of lymphocyte migration(GO:2000402) regulation of natural killer cell chemotaxis(GO:2000501)
0.2 5.7 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.2 3.8 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.1 9.2 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.1 3.1 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.1 1.7 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.1 1.2 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 2.7 GO:1903427 negative regulation of reactive oxygen species biosynthetic process(GO:1903427)
0.1 3.7 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 3.2 GO:0007608 sensory perception of smell(GO:0007608)
0.1 0.8 GO:0036506 maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1 6.9 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 1.5 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.1 0.1 GO:0019062 virion attachment to host cell(GO:0019062) adhesion of symbiont to host cell(GO:0044650)
0.1 1.0 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.1 0.2 GO:0060854 patterning of lymph vessels(GO:0060854)
0.1 3.9 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 0.4 GO:1901911 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 1.1 GO:0044381 glucose import in response to insulin stimulus(GO:0044381)
0.1 0.9 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 1.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 3.4 GO:0008584 male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.0 3.0 GO:0061515 myeloid cell development(GO:0061515)
0.0 1.3 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.2 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.1 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.0 3.5 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 4.1 GO:0008033 tRNA processing(GO:0008033)
0.0 1.2 GO:0006414 translational elongation(GO:0006414)
0.0 4.2 GO:0042254 ribosome biogenesis(GO:0042254)
0.0 3.5 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 1.1 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.0 0.1 GO:0045583 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.0 0.7 GO:0031338 regulation of vesicle fusion(GO:0031338)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.5 13.5 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
3.6 14.5 GO:0045098 type III intermediate filament(GO:0045098)
3.6 119.5 GO:0000788 nuclear nucleosome(GO:0000788)
3.6 10.8 GO:0033596 TSC1-TSC2 complex(GO:0033596)
2.0 14.3 GO:0097452 GAIT complex(GO:0097452)
1.5 9.3 GO:0032299 ribonuclease H2 complex(GO:0032299)
1.3 5.4 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
1.3 7.8 GO:0005859 muscle myosin complex(GO:0005859)
1.3 48.5 GO:0000786 nucleosome(GO:0000786)
1.1 6.8 GO:0097512 cardiac myofibril(GO:0097512)
1.1 5.7 GO:0034715 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
1.1 4.5 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
1.1 8.7 GO:0005833 hemoglobin complex(GO:0005833)
1.0 3.1 GO:0005584 collagen type I trimer(GO:0005584)
1.0 5.2 GO:0001652 granular component(GO:0001652)
1.0 4.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.9 7.4 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.8 4.9 GO:0071817 MMXD complex(GO:0071817)
0.8 4.0 GO:1990357 terminal web(GO:1990357)
0.8 3.9 GO:0097443 sorting endosome(GO:0097443)
0.8 19.3 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.7 3.7 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.7 8.1 GO:0042612 MHC class I protein complex(GO:0042612)
0.7 34.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.7 2.7 GO:0032021 NELF complex(GO:0032021)
0.7 6.6 GO:0045298 tubulin complex(GO:0045298)
0.6 15.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.6 3.8 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.6 3.0 GO:0001533 cornified envelope(GO:0001533)
0.4 9.0 GO:0010369 chromocenter(GO:0010369)
0.4 2.7 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.4 1.4 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.3 5.1 GO:0044754 autolysosome(GO:0044754)
0.3 18.4 GO:0005871 kinesin complex(GO:0005871)
0.3 2.0 GO:0034366 spherical high-density lipoprotein particle(GO:0034366) neurofibrillary tangle(GO:0097418)
0.2 4.0 GO:0031045 dense core granule(GO:0031045)
0.2 11.3 GO:0005876 spindle microtubule(GO:0005876)
0.2 0.6 GO:0036128 CatSper complex(GO:0036128)
0.2 3.8 GO:0045120 pronucleus(GO:0045120)
0.2 20.9 GO:0005814 centriole(GO:0005814)
0.2 1.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2 2.8 GO:0042405 nuclear inclusion body(GO:0042405)
0.2 1.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.2 8.5 GO:0005882 intermediate filament(GO:0005882)
0.2 1.5 GO:0042382 paraspeckles(GO:0042382)
0.2 2.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.2 8.0 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 2.2 GO:0031091 platelet alpha granule(GO:0031091)
0.1 9.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 1.6 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 0.9 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.1 0.8 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 4.3 GO:0002102 podosome(GO:0002102)
0.1 1.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 7.2 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.1 3.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 19.3 GO:0043209 myelin sheath(GO:0043209)
0.1 3.6 GO:0043034 costamere(GO:0043034)
0.1 1.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 1.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 7.7 GO:0000776 kinetochore(GO:0000776)
0.1 23.1 GO:0000790 nuclear chromatin(GO:0000790)
0.1 17.8 GO:0005667 transcription factor complex(GO:0005667)
0.1 1.2 GO:0009925 basal plasma membrane(GO:0009925)
0.1 3.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.0 GO:0002080 acrosomal membrane(GO:0002080)
0.0 8.9 GO:0031965 nuclear membrane(GO:0031965)
0.0 18.6 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 2.6 GO:0005581 collagen trimer(GO:0005581)
0.0 6.5 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.9 GO:0000793 condensed chromosome(GO:0000793)
0.0 59.3 GO:0005654 nucleoplasm(GO:0005654)
0.0 14.9 GO:0005730 nucleolus(GO:0005730)
0.0 1.2 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 1.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 2.0 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 65.3 GO:0005634 nucleus(GO:0005634)
0.0 1.4 GO:0043195 terminal bouton(GO:0043195)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
6.5 32.6 GO:0005344 oxygen transporter activity(GO:0005344)
5.5 32.8 GO:0019841 retinol binding(GO:0019841)
4.8 14.3 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
3.6 14.5 GO:1990254 keratin filament binding(GO:1990254)
3.5 10.5 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
2.9 11.7 GO:0004111 creatine kinase activity(GO:0004111)
2.9 29.0 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
2.7 13.5 GO:0035240 dopamine binding(GO:0035240)
2.3 9.3 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
1.9 94.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
1.9 15.1 GO:0005212 structural constituent of eye lens(GO:0005212)
1.9 5.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
1.8 7.0 GO:0019808 polyamine binding(GO:0019808)
1.7 11.6 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
1.6 7.8 GO:0051371 muscle alpha-actinin binding(GO:0051371)
1.3 9.3 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
1.3 3.8 GO:0071633 dihydroceramidase activity(GO:0071633)
1.2 16.0 GO:0019855 calcium channel inhibitor activity(GO:0019855)
1.2 4.8 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
1.2 4.8 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
1.1 5.4 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
1.0 4.0 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
1.0 8.8 GO:0032564 dATP binding(GO:0032564)
0.9 19.8 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.8 4.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.8 7.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.8 3.9 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.7 9.9 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.7 2.7 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.6 16.3 GO:0043274 phospholipase binding(GO:0043274)
0.6 8.1 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.6 2.8 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.5 3.2 GO:0004984 olfactory receptor activity(GO:0004984)
0.5 3.6 GO:0016018 cyclosporin A binding(GO:0016018)
0.5 20.7 GO:0005507 copper ion binding(GO:0005507)
0.5 4.9 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.5 5.8 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.5 10.6 GO:0070628 proteasome binding(GO:0070628)
0.4 2.2 GO:0015265 urea channel activity(GO:0015265)
0.4 11.8 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.4 2.8 GO:0000403 Y-form DNA binding(GO:0000403)
0.4 1.2 GO:0004875 complement receptor activity(GO:0004875)
0.4 3.8 GO:1990715 mRNA CDS binding(GO:1990715)
0.4 1.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.4 4.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.4 6.0 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.3 13.9 GO:0005504 fatty acid binding(GO:0005504)
0.3 10.4 GO:0071837 HMG box domain binding(GO:0071837)
0.3 6.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.3 60.4 GO:0042393 histone binding(GO:0042393)
0.3 8.0 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.3 6.9 GO:0003785 actin monomer binding(GO:0003785)
0.3 1.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.2 10.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.2 18.4 GO:0003777 microtubule motor activity(GO:0003777)
0.2 3.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 0.2 GO:0015254 glycerol channel activity(GO:0015254)
0.2 6.8 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.2 0.9 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.2 7.9 GO:0016504 peptidase activator activity(GO:0016504)
0.2 31.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 1.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.2 1.5 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.2 0.5 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.2 3.8 GO:0097602 cullin family protein binding(GO:0097602)
0.2 4.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 3.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 3.0 GO:0008266 poly(U) RNA binding(GO:0008266)
0.2 1.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 2.0 GO:0051787 misfolded protein binding(GO:0051787)
0.1 0.2 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.1 3.9 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 9.8 GO:0002020 protease binding(GO:0002020)
0.1 0.4 GO:0070330 aromatase activity(GO:0070330)
0.1 1.2 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 0.3 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 2.7 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 6.9 GO:0005506 iron ion binding(GO:0005506)
0.1 1.7 GO:0017091 AU-rich element binding(GO:0017091)
0.1 0.9 GO:0070097 delta-catenin binding(GO:0070097)
0.1 1.0 GO:0005537 mannose binding(GO:0005537)
0.1 1.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.4 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 1.8 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.1 3.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.3 GO:0042805 actinin binding(GO:0042805)
0.1 3.6 GO:0097110 scaffold protein binding(GO:0097110)
0.1 107.0 GO:0003677 DNA binding(GO:0003677)
0.1 3.4 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 2.7 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.1 1.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.6 GO:0051861 glycolipid binding(GO:0051861)
0.0 7.6 GO:0051015 actin filament binding(GO:0051015)
0.0 1.6 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.1 GO:0016880 acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.1 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.8 GO:0051087 chaperone binding(GO:0051087)
0.0 3.9 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 24.1 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.8 40.0 PID_AURORA_B_PATHWAY Aurora B signaling
0.6 10.5 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.5 16.5 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.5 20.3 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.3 20.6 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.3 10.6 PID_IL3_PATHWAY IL3-mediated signaling events
0.3 9.1 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.3 30.8 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.2 5.7 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.2 7.2 PID_AR_NONGENOMIC_PATHWAY Nongenotropic Androgen signaling
0.2 9.3 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 4.8 PID_AURORA_A_PATHWAY Aurora A signaling
0.2 5.3 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.2 3.1 PID_LYMPH_ANGIOGENESIS_PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 3.8 PID_ATM_PATHWAY ATM pathway
0.1 11.2 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.1 6.4 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.1 3.7 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.1 6.5 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.1 2.2 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.1 4.0 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.1 2.0 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.1 5.7 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.1 1.1 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.1 3.0 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.9 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 1.0 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 1.7 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.2 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 1.0 PID_TGFBR_PATHWAY TGF-beta receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 164.6 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
2.5 7.4 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
2.1 10.5 REACTOME_ANDROGEN_BIOSYNTHESIS Genes involved in Androgen biosynthesis
1.7 27.7 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
1.3 11.6 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
1.2 13.5 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.9 22.4 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.8 4.8 REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.7 18.4 REACTOME_KINESINS Genes involved in Kinesins
0.6 16.1 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.6 34.5 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.6 5.4 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.6 7.4 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.5 5.7 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.5 7.5 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.5 3.6 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.4 10.8 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.4 6.9 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.4 13.5 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.4 5.8 REACTOME_PHOSPHORYLATION_OF_THE_APC_C Genes involved in Phosphorylation of the APC/C
0.4 3.9 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.3 14.3 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.3 14.8 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.2 13.7 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.2 2.7 REACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.2 11.8 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.2 6.0 REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.1 4.9 REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.1 2.3 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 1.2 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.1 9.8 REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE Genes involved in Late Phase of HIV Life Cycle
0.1 8.0 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.1 2.2 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 2.7 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 1.1 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 1.0 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 3.8 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 3.2 REACTOME_IRON_UPTAKE_AND_TRANSPORT Genes involved in Iron uptake and transport
0.1 11.4 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.1 1.4 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 10.0 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 1.0 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism
0.0 3.8 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.0 1.0 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 4.3 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 2.6 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.2 REACTOME_TRANSLATION Genes involved in Translation
0.0 2.2 REACTOME_SIGNALING_BY_PDGF Genes involved in Signaling by PDGF
0.0 0.6 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis