Motif ID: E2f3
Z-value: 0.940

Transcription factors associated with E2f3:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
E2f3 | ENSMUSG00000016477.11 | E2f3 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
E2f3 | mm10_v2_chr13_-_29984219_29984353 | 0.28 | 7.9e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.1 | 3.2 | GO:0035934 | corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852) |
0.9 | 2.6 | GO:0030200 | heparan sulfate proteoglycan catabolic process(GO:0030200) |
0.7 | 5.3 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
0.4 | 2.1 | GO:0010792 | DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) |
0.4 | 1.2 | GO:2000620 | positive regulation of histone H4-K16 acetylation(GO:2000620) |
0.4 | 1.1 | GO:0019085 | early viral transcription(GO:0019085) |
0.3 | 2.4 | GO:0070863 | positive regulation of protein exit from endoplasmic reticulum(GO:0070863) |
0.3 | 1.8 | GO:0030214 | hyaluronan catabolic process(GO:0030214) |
0.3 | 1.2 | GO:0035624 | mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) response to high density lipoprotein particle(GO:0055099) |
0.3 | 0.9 | GO:0007161 | calcium-independent cell-matrix adhesion(GO:0007161) |
0.3 | 1.8 | GO:0044806 | G-quadruplex DNA unwinding(GO:0044806) |
0.3 | 0.8 | GO:0006295 | nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295) |
0.2 | 1.0 | GO:0009957 | epidermal cell fate specification(GO:0009957) |
0.2 | 2.1 | GO:0033504 | floor plate development(GO:0033504) |
0.2 | 0.9 | GO:0006420 | arginyl-tRNA aminoacylation(GO:0006420) |
0.2 | 1.1 | GO:0060923 | cardiac muscle cell fate commitment(GO:0060923) |
0.2 | 1.2 | GO:0046490 | isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490) |
0.2 | 0.6 | GO:0090204 | protein localization to nuclear pore(GO:0090204) negative regulation of vascular endothelial growth factor production(GO:1904046) |
0.2 | 1.3 | GO:0033567 | DNA replication, Okazaki fragment processing(GO:0033567) |
0.2 | 1.1 | GO:0042276 | error-prone translesion synthesis(GO:0042276) |
0.2 | 0.9 | GO:0003376 | sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520) |
0.2 | 0.7 | GO:0055071 | cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071) |
0.2 | 0.7 | GO:0031622 | positive regulation of fever generation(GO:0031622) negative regulation of action potential(GO:0045759) trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553) |
0.2 | 1.3 | GO:0044791 | modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) |
0.2 | 3.7 | GO:0043486 | histone exchange(GO:0043486) |
0.2 | 1.7 | GO:0051307 | meiotic chromosome separation(GO:0051307) |
0.2 | 0.8 | GO:0010025 | wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166) |
0.2 | 2.4 | GO:0006312 | mitotic recombination(GO:0006312) |
0.1 | 0.4 | GO:0071579 | regulation of zinc ion transport(GO:0071579) |
0.1 | 0.9 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
0.1 | 1.3 | GO:0098789 | pre-mRNA cleavage required for polyadenylation(GO:0098789) |
0.1 | 0.7 | GO:0048478 | replication fork protection(GO:0048478) |
0.1 | 2.0 | GO:0009263 | deoxyribonucleotide biosynthetic process(GO:0009263) |
0.1 | 2.0 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
0.1 | 1.2 | GO:0048484 | enteric nervous system development(GO:0048484) |
0.1 | 1.0 | GO:0035873 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879) |
0.1 | 1.0 | GO:2000051 | negative regulation of non-canonical Wnt signaling pathway(GO:2000051) |
0.1 | 0.4 | GO:0006680 | glucosylceramide catabolic process(GO:0006680) |
0.1 | 1.6 | GO:0072520 | seminiferous tubule development(GO:0072520) |
0.1 | 2.3 | GO:0045662 | negative regulation of myoblast differentiation(GO:0045662) |
0.1 | 0.3 | GO:0048633 | positive regulation of skeletal muscle tissue growth(GO:0048633) |
0.1 | 0.3 | GO:0071963 | establishment or maintenance of cell polarity regulating cell shape(GO:0071963) |
0.1 | 0.6 | GO:0070779 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
0.1 | 0.2 | GO:0035672 | transepithelial chloride transport(GO:0030321) oligopeptide transmembrane transport(GO:0035672) |
0.1 | 0.2 | GO:0001787 | natural killer cell proliferation(GO:0001787) |
0.1 | 0.4 | GO:0036337 | Fas signaling pathway(GO:0036337) |
0.1 | 0.7 | GO:0035562 | negative regulation of chromatin binding(GO:0035562) |
0.1 | 0.7 | GO:1904152 | negative regulation of protein exit from endoplasmic reticulum(GO:0070862) regulation of retrograde protein transport, ER to cytosol(GO:1904152) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153) |
0.1 | 1.1 | GO:0036120 | cellular response to platelet-derived growth factor stimulus(GO:0036120) |
0.1 | 0.3 | GO:0090647 | modulation of age-related behavioral decline(GO:0090647) negative regulation of metalloendopeptidase activity(GO:1904684) |
0.1 | 0.3 | GO:0042758 | long-chain fatty acid catabolic process(GO:0042758) |
0.1 | 0.3 | GO:0090245 | axis elongation involved in somitogenesis(GO:0090245) |
0.1 | 0.2 | GO:0010360 | negative regulation of anion channel activity(GO:0010360) |
0.1 | 0.4 | GO:2000973 | regulation of pro-B cell differentiation(GO:2000973) |
0.1 | 0.6 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
0.1 | 0.2 | GO:0050859 | negative regulation of B cell receptor signaling pathway(GO:0050859) |
0.1 | 0.2 | GO:0036388 | pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299) |
0.1 | 0.6 | GO:0031936 | negative regulation of chromatin silencing(GO:0031936) |
0.1 | 0.4 | GO:0019985 | translesion synthesis(GO:0019985) |
0.1 | 0.2 | GO:0071034 | CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051) |
0.1 | 0.9 | GO:0060033 | anatomical structure regression(GO:0060033) |
0.1 | 0.4 | GO:0006271 | DNA strand elongation involved in DNA replication(GO:0006271) mitotic DNA replication(GO:1902969) |
0.1 | 0.2 | GO:0000957 | mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960) mitochondrial RNA 3'-end processing(GO:0000965) |
0.1 | 0.8 | GO:0060213 | regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) |
0.1 | 0.7 | GO:0097067 | negative regulation of erythrocyte differentiation(GO:0045647) cellular response to thyroid hormone stimulus(GO:0097067) |
0.1 | 0.9 | GO:0007131 | reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825) |
0.1 | 0.6 | GO:0060019 | radial glial cell differentiation(GO:0060019) |
0.1 | 2.8 | GO:0048384 | retinoic acid receptor signaling pathway(GO:0048384) |
0.1 | 0.8 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
0.1 | 0.4 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
0.1 | 0.2 | GO:0043686 | co-translational protein modification(GO:0043686) |
0.0 | 0.3 | GO:1901837 | negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837) |
0.0 | 0.5 | GO:0046784 | viral mRNA export from host cell nucleus(GO:0046784) |
0.0 | 0.5 | GO:1902416 | positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216) |
0.0 | 1.2 | GO:0031290 | retinal ganglion cell axon guidance(GO:0031290) |
0.0 | 0.4 | GO:0010764 | negative regulation of fibroblast migration(GO:0010764) |
0.0 | 0.6 | GO:0060052 | neurofilament cytoskeleton organization(GO:0060052) |
0.0 | 0.4 | GO:0034244 | negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244) |
0.0 | 1.4 | GO:0035329 | hippo signaling(GO:0035329) |
0.0 | 1.9 | GO:0000266 | mitochondrial fission(GO:0000266) |
0.0 | 0.1 | GO:0006121 | mitochondrial electron transport, succinate to ubiquinone(GO:0006121) |
0.0 | 1.5 | GO:0033120 | positive regulation of RNA splicing(GO:0033120) |
0.0 | 0.4 | GO:0001731 | formation of translation preinitiation complex(GO:0001731) |
0.0 | 0.2 | GO:0051152 | positive regulation of smooth muscle cell differentiation(GO:0051152) |
0.0 | 0.1 | GO:1901341 | activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341) |
0.0 | 0.1 | GO:0031990 | mRNA export from nucleus in response to heat stress(GO:0031990) |
0.0 | 1.3 | GO:0046579 | positive regulation of Ras protein signal transduction(GO:0046579) |
0.0 | 0.4 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
0.0 | 0.7 | GO:0007638 | mechanosensory behavior(GO:0007638) |
0.0 | 0.2 | GO:1901409 | positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
0.0 | 0.6 | GO:0071218 | cellular response to misfolded protein(GO:0071218) |
0.0 | 0.5 | GO:0070208 | protein heterotrimerization(GO:0070208) |
0.0 | 0.2 | GO:2000773 | negative regulation of cellular senescence(GO:2000773) |
0.0 | 0.5 | GO:0071539 | protein localization to centrosome(GO:0071539) |
0.0 | 0.1 | GO:1902751 | positive regulation of cell cycle G2/M phase transition(GO:1902751) |
0.0 | 1.4 | GO:0097194 | execution phase of apoptosis(GO:0097194) |
0.0 | 0.4 | GO:0034243 | regulation of transcription elongation from RNA polymerase II promoter(GO:0034243) |
0.0 | 0.3 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
0.0 | 1.2 | GO:0010634 | positive regulation of epithelial cell migration(GO:0010634) |
0.0 | 0.1 | GO:1902309 | negative regulation of peptidyl-serine dephosphorylation(GO:1902309) |
0.0 | 0.7 | GO:0031122 | cytoplasmic microtubule organization(GO:0031122) |
0.0 | 0.1 | GO:0030206 | chondroitin sulfate biosynthetic process(GO:0030206) |
0.0 | 0.3 | GO:0021854 | hypothalamus development(GO:0021854) |
0.0 | 0.1 | GO:0033262 | regulation of nuclear cell cycle DNA replication(GO:0033262) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 1.8 | GO:0000799 | nuclear condensin complex(GO:0000799) |
0.5 | 3.5 | GO:0000796 | condensin complex(GO:0000796) |
0.4 | 2.0 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
0.3 | 1.3 | GO:0034991 | nuclear meiotic cohesin complex(GO:0034991) |
0.3 | 2.1 | GO:0005828 | kinetochore microtubule(GO:0005828) |
0.2 | 1.1 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
0.2 | 0.6 | GO:0035061 | interchromatin granule(GO:0035061) |
0.2 | 1.2 | GO:0070531 | BRCA1-A complex(GO:0070531) |
0.2 | 0.5 | GO:0034657 | GID complex(GO:0034657) |
0.2 | 0.2 | GO:0031261 | DNA replication preinitiation complex(GO:0031261) |
0.2 | 1.0 | GO:0000938 | GARP complex(GO:0000938) |
0.2 | 2.1 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
0.2 | 1.8 | GO:0071598 | neuronal ribonucleoprotein granule(GO:0071598) |
0.1 | 0.7 | GO:0031298 | replication fork protection complex(GO:0031298) |
0.1 | 0.4 | GO:0000811 | GINS complex(GO:0000811) |
0.1 | 1.1 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
0.1 | 0.4 | GO:0032021 | NELF complex(GO:0032021) |
0.1 | 0.3 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
0.1 | 0.9 | GO:0071439 | clathrin complex(GO:0071439) |
0.1 | 0.6 | GO:0044613 | nuclear pore central transport channel(GO:0044613) |
0.1 | 2.0 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
0.1 | 1.4 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
0.1 | 0.8 | GO:0005675 | holo TFIIH complex(GO:0005675) |
0.1 | 0.4 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
0.1 | 0.8 | GO:0005779 | integral component of peroxisomal membrane(GO:0005779) |
0.1 | 0.5 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
0.0 | 0.6 | GO:0016442 | RISC complex(GO:0016442) RNAi effector complex(GO:0031332) |
0.0 | 0.4 | GO:0005744 | mitochondrial inner membrane presequence translocase complex(GO:0005744) |
0.0 | 0.3 | GO:0001740 | Barr body(GO:0001740) |
0.0 | 0.2 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
0.0 | 0.5 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
0.0 | 2.1 | GO:0005871 | kinesin complex(GO:0005871) |
0.0 | 0.6 | GO:0034451 | centriolar satellite(GO:0034451) |
0.0 | 0.3 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
0.0 | 1.0 | GO:0016592 | mediator complex(GO:0016592) |
0.0 | 0.7 | GO:0035371 | microtubule plus-end(GO:0035371) |
0.0 | 0.3 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
0.0 | 0.2 | GO:0030127 | COPII vesicle coat(GO:0030127) |
0.0 | 2.1 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
0.0 | 2.4 | GO:0005814 | centriole(GO:0005814) |
0.0 | 0.5 | GO:0016580 | Sin3 complex(GO:0016580) |
0.0 | 0.5 | GO:0045120 | pronucleus(GO:0045120) |
0.0 | 1.3 | GO:0072686 | mitotic spindle(GO:0072686) |
0.0 | 0.1 | GO:0005638 | lamin filament(GO:0005638) |
0.0 | 0.6 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
0.0 | 0.6 | GO:0030673 | axolemma(GO:0030673) |
0.0 | 0.2 | GO:0045298 | tubulin complex(GO:0045298) |
0.0 | 0.2 | GO:0097225 | sperm midpiece(GO:0097225) |
0.0 | 0.4 | GO:0035869 | ciliary transition zone(GO:0035869) |
0.0 | 1.0 | GO:0036064 | ciliary basal body(GO:0036064) |
0.0 | 0.9 | GO:0005604 | basement membrane(GO:0005604) |
0.0 | 0.1 | GO:0005849 | mRNA cleavage factor complex(GO:0005849) |
0.0 | 0.8 | GO:0016605 | PML body(GO:0016605) |
0.0 | 2.5 | GO:0009897 | external side of plasma membrane(GO:0009897) |
0.0 | 4.0 | GO:0045121 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
0.0 | 1.2 | GO:0043195 | terminal bouton(GO:0043195) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 1.8 | GO:0004415 | hyalurononglucosaminidase activity(GO:0004415) |
0.4 | 2.6 | GO:0045545 | syndecan binding(GO:0045545) |
0.4 | 2.0 | GO:0061731 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
0.4 | 1.2 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
0.3 | 1.3 | GO:0036033 | mediator complex binding(GO:0036033) |
0.3 | 1.0 | GO:0005119 | smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158) |
0.3 | 1.8 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
0.3 | 1.8 | GO:0044547 | DNA topoisomerase binding(GO:0044547) |
0.2 | 0.9 | GO:0004814 | arginine-tRNA ligase activity(GO:0004814) |
0.2 | 1.3 | GO:0003910 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
0.2 | 0.6 | GO:0004534 | 5'-3' exoribonuclease activity(GO:0004534) |
0.2 | 2.1 | GO:0000014 | single-stranded DNA endodeoxyribonuclease activity(GO:0000014) |
0.2 | 0.7 | GO:0015410 | manganese-transporting ATPase activity(GO:0015410) |
0.2 | 0.8 | GO:0000405 | bubble DNA binding(GO:0000405) |
0.2 | 3.2 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
0.2 | 0.5 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
0.2 | 0.8 | GO:0080019 | fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019) |
0.2 | 1.2 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
0.2 | 0.9 | GO:0008821 | crossover junction endodeoxyribonuclease activity(GO:0008821) |
0.1 | 1.1 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
0.1 | 2.8 | GO:0003708 | retinoic acid receptor activity(GO:0003708) |
0.1 | 2.7 | GO:0015035 | protein disulfide oxidoreductase activity(GO:0015035) |
0.1 | 0.9 | GO:0000150 | recombinase activity(GO:0000150) |
0.1 | 2.1 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
0.1 | 0.3 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
0.1 | 0.3 | GO:0017150 | tRNA dihydrouridine synthase activity(GO:0017150) |
0.1 | 0.4 | GO:0070976 | calcium-independent protein kinase C activity(GO:0004699) TIR domain binding(GO:0070976) |
0.1 | 0.9 | GO:0038036 | sphingosine-1-phosphate receptor activity(GO:0038036) |
0.1 | 1.2 | GO:0016863 | intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863) |
0.1 | 0.6 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
0.1 | 7.5 | GO:0005249 | voltage-gated potassium channel activity(GO:0005249) |
0.1 | 0.4 | GO:0004809 | tRNA (guanine-N2-)-methyltransferase activity(GO:0004809) |
0.1 | 0.3 | GO:0004466 | long-chain-acyl-CoA dehydrogenase activity(GO:0004466) |
0.1 | 0.2 | GO:0019166 | trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166) |
0.1 | 0.6 | GO:0050733 | RS domain binding(GO:0050733) |
0.1 | 0.3 | GO:0031727 | CCR2 chemokine receptor binding(GO:0031727) |
0.1 | 0.4 | GO:0032184 | SUMO polymer binding(GO:0032184) |
0.1 | 1.8 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
0.1 | 0.4 | GO:0071074 | eukaryotic initiation factor eIF2 binding(GO:0071074) |
0.1 | 0.4 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
0.1 | 0.5 | GO:1990715 | mRNA CDS binding(GO:1990715) |
0.1 | 0.2 | GO:0015563 | uptake transmembrane transporter activity(GO:0015563) |
0.1 | 0.4 | GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450) |
0.1 | 0.2 | GO:0004703 | G-protein coupled receptor kinase activity(GO:0004703) |
0.0 | 0.4 | GO:0043138 | 3'-5' DNA helicase activity(GO:0043138) |
0.0 | 0.2 | GO:0052743 | inositol tetrakisphosphate phosphatase activity(GO:0052743) |
0.0 | 1.1 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
0.0 | 0.4 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
0.0 | 0.2 | GO:0061665 | SUMO ligase activity(GO:0061665) |
0.0 | 1.1 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
0.0 | 1.1 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
0.0 | 0.7 | GO:0070888 | E-box binding(GO:0070888) |
0.0 | 0.1 | GO:0034481 | chondroitin sulfotransferase activity(GO:0034481) |
0.0 | 2.7 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
0.0 | 1.4 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
0.0 | 0.6 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
0.0 | 1.2 | GO:0003684 | damaged DNA binding(GO:0003684) |
0.0 | 0.4 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
0.0 | 2.0 | GO:0003777 | microtubule motor activity(GO:0003777) |
0.0 | 0.5 | GO:0030506 | ankyrin binding(GO:0030506) |
0.0 | 0.6 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
0.0 | 0.3 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
0.0 | 0.9 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
0.0 | 7.2 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
0.0 | 0.2 | GO:0003688 | DNA replication origin binding(GO:0003688) |
0.0 | 0.7 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
0.0 | 0.6 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
0.0 | 0.3 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
0.0 | 0.1 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
0.0 | 1.2 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
0.0 | 2.9 | GO:0042393 | histone binding(GO:0042393) |
0.0 | 0.2 | GO:0003678 | DNA helicase activity(GO:0003678) |
0.0 | 1.1 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
0.0 | 0.6 | GO:0050840 | extracellular matrix binding(GO:0050840) |
0.0 | 0.3 | GO:0031489 | myosin V binding(GO:0031489) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 5.7 | PID_ATM_PATHWAY | ATM pathway |
0.1 | 3.5 | PID_HEDGEHOG_2PATHWAY | Signaling events mediated by the Hedgehog family |
0.1 | 5.3 | PID_AURORA_B_PATHWAY | Aurora B signaling |
0.0 | 1.2 | PID_NECTIN_PATHWAY | Nectin adhesion pathway |
0.0 | 0.9 | PID_S1P_S1P2_PATHWAY | S1P2 pathway |
0.0 | 1.6 | PID_ALPHA_SYNUCLEIN_PATHWAY | Alpha-synuclein signaling |
0.0 | 0.4 | SA_PROGRAMMED_CELL_DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
0.0 | 1.2 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
0.0 | 1.2 | PID_ERBB4_PATHWAY | ErbB4 signaling events |
0.0 | 1.9 | PID_ERA_GENOMIC_PATHWAY | Validated nuclear estrogen receptor alpha network |
0.0 | 1.9 | PID_E2F_PATHWAY | E2F transcription factor network |
0.0 | 0.3 | ST_INTERLEUKIN_4_PATHWAY | Interleukin 4 (IL-4) Pathway |
0.0 | 0.7 | PID_NCADHERIN_PATHWAY | N-cadherin signaling events |
0.0 | 0.7 | PID_ATR_PATHWAY | ATR signaling pathway |
0.0 | 0.2 | ST_JAK_STAT_PATHWAY | Jak-STAT Pathway |
0.0 | 2.4 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
0.0 | 0.1 | PID_AR_NONGENOMIC_PATHWAY | Nongenotropic Androgen signaling |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 3.4 | REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
0.2 | 7.5 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
0.1 | 3.3 | REACTOME_KINESINS | Genes involved in Kinesins |
0.1 | 2.6 | REACTOME_HS_GAG_DEGRADATION | Genes involved in HS-GAG degradation |
0.1 | 2.1 | REACTOME_G1_S_SPECIFIC_TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
0.1 | 1.1 | REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER | Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER |
0.1 | 1.2 | REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR | Genes involved in Regulated proteolysis of p75NTR |
0.1 | 1.1 | REACTOME_PECAM1_INTERACTIONS | Genes involved in PECAM1 interactions |
0.1 | 3.9 | REACTOME_MEIOTIC_RECOMBINATION | Genes involved in Meiotic Recombination |
0.1 | 0.1 | REACTOME_AUTODEGRADATION_OF_THE_E3_UBIQUITIN_LIGASE_COP1 | Genes involved in Autodegradation of the E3 ubiquitin ligase COP1 |
0.1 | 0.8 | REACTOME_ERKS_ARE_INACTIVATED | Genes involved in ERKs are inactivated |
0.1 | 1.2 | REACTOME_CHOLESTEROL_BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
0.0 | 0.8 | REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP | Genes involved in Destabilization of mRNA by Tristetraprolin (TTP) |
0.0 | 1.5 | REACTOME_SIGNALING_BY_HIPPO | Genes involved in Signaling by Hippo |
0.0 | 0.8 | REACTOME_TRANSCRIPTION_COUPLED_NER_TC_NER | Genes involved in Transcription-coupled NER (TC-NER) |
0.0 | 1.2 | REACTOME_ELONGATION_ARREST_AND_RECOVERY | Genes involved in Elongation arrest and recovery |
0.0 | 2.8 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
0.0 | 0.9 | REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
0.0 | 3.2 | REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS | Genes involved in Peptide ligand-binding receptors |
0.0 | 1.3 | REACTOME_MEIOTIC_SYNAPSIS | Genes involved in Meiotic Synapsis |
0.0 | 0.4 | REACTOME_ZINC_TRANSPORTERS | Genes involved in Zinc transporters |
0.0 | 0.4 | REACTOME_ACTIVATION_OF_RAC | Genes involved in Activation of Rac |
0.0 | 0.2 | REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION | Genes involved in E2F-enabled inhibition of pre-replication complex formation |
0.0 | 1.2 | REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS | Genes involved in Class A/1 (Rhodopsin-like receptors) |
0.0 | 0.8 | REACTOME_PEROXISOMAL_LIPID_METABOLISM | Genes involved in Peroxisomal lipid metabolism |
0.0 | 2.9 | REACTOME_MRNA_SPLICING | Genes involved in mRNA Splicing |
0.0 | 0.7 | REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN | Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein |
0.0 | 0.2 | REACTOME_REGULATION_OF_IFNG_SIGNALING | Genes involved in Regulation of IFNG signaling |
0.0 | 0.3 | REACTOME_MTORC1_MEDIATED_SIGNALLING | Genes involved in mTORC1-mediated signalling |
0.0 | 0.3 | REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
0.0 | 0.7 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | Genes involved in Ion transport by P-type ATPases |
0.0 | 0.2 | REACTOME_PROLACTIN_RECEPTOR_SIGNALING | Genes involved in Prolactin receptor signaling |
0.0 | 0.2 | REACTOME_GENERIC_TRANSCRIPTION_PATHWAY | Genes involved in Generic Transcription Pathway |
0.0 | 0.4 | REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
0.0 | 1.0 | REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |