Motif ID: Tbx5

Z-value: 0.753


Transcription factors associated with Tbx5:

Gene SymbolEntrez IDGene Name
Tbx5 ENSMUSG00000018263.8 Tbx5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tbx5mm10_v2_chr5_+_119834663_119834663-0.153.5e-01Click!


Activity profile for motif Tbx5.

activity profile for motif Tbx5


Sorted Z-values histogram for motif Tbx5

Sorted Z-values for motif Tbx5



Network of associatons between targets according to the STRING database.



First level regulatory network of Tbx5

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_26229707 7.295 ENSMUST00000060716.5
ENSMUST00000164660.1
Samd3

sterile alpha motif domain containing 3

chr1_-_138848576 4.868 ENSMUST00000112030.2
Lhx9
LIM homeobox protein 9
chr14_+_122475397 4.038 ENSMUST00000075888.5
Zic2
zinc finger protein of the cerebellum 2
chr4_-_134018829 2.788 ENSMUST00000051674.2
Lin28a
lin-28 homolog A (C. elegans)
chr9_-_43239816 2.725 ENSMUST00000034512.5
Oaf
OAF homolog (Drosophila)
chr4_-_41517326 2.482 ENSMUST00000030152.6
ENSMUST00000095126.4
1110017D15Rik

RIKEN cDNA 1110017D15 gene

chr2_-_54085542 2.427 ENSMUST00000100089.2
Rprm
reprimo, TP53 dependent G2 arrest mediator candidate
chr7_-_28302238 2.405 ENSMUST00000108315.3
Dll3
delta-like 3 (Drosophila)
chr10_-_120899067 2.314 ENSMUST00000092143.5
Msrb3
methionine sulfoxide reductase B3
chr4_+_128883549 2.203 ENSMUST00000035667.8
Trim62
tripartite motif-containing 62
chr3_+_126596951 2.154 ENSMUST00000106402.1
Camk2d
calcium/calmodulin-dependent protein kinase II, delta
chr15_-_98004634 2.069 ENSMUST00000131560.1
ENSMUST00000088355.5
Col2a1

collagen, type II, alpha 1

chr5_-_5514730 2.048 ENSMUST00000115445.1
ENSMUST00000179804.1
ENSMUST00000125110.1
ENSMUST00000115446.1
Cldn12



claudin 12



chr15_-_98004695 1.999 ENSMUST00000023123.8
Col2a1
collagen, type II, alpha 1
chr7_-_79594924 1.948 ENSMUST00000172788.1
Rhcg
Rhesus blood group-associated C glycoprotein
chr5_-_5514873 1.935 ENSMUST00000060947.7
Cldn12
claudin 12
chr10_+_79682304 1.934 ENSMUST00000166603.1
Cdc34
cell division cycle 34
chr2_+_103970221 1.925 ENSMUST00000111140.2
ENSMUST00000111139.2
Lmo2

LIM domain only 2

chr14_-_70642268 1.918 ENSMUST00000022697.5
Fgf17
fibroblast growth factor 17
chr10_+_93641041 1.906 ENSMUST00000020204.4
Ntn4
netrin 4
chr10_+_79682169 1.869 ENSMUST00000020550.5
Cdc34
cell division cycle 34
chr2_+_103970115 1.846 ENSMUST00000111143.1
ENSMUST00000138815.1
Lmo2

LIM domain only 2

chr17_-_70851189 1.733 ENSMUST00000059775.8
Tgif1
TGFB-induced factor homeobox 1
chr3_+_126596993 1.730 ENSMUST00000163226.1
ENSMUST00000066466.6
ENSMUST00000169051.1
Camk2d


calcium/calmodulin-dependent protein kinase II, delta


chr9_+_107400043 1.698 ENSMUST00000166799.1
ENSMUST00000170737.1
Cacna2d2

calcium channel, voltage-dependent, alpha 2/delta subunit 2

chr3_+_123446913 1.655 ENSMUST00000029603.8
Prss12
protease, serine, 12 neurotrypsin (motopsin)
chr11_+_94741782 1.608 ENSMUST00000021240.6
Cdc34-ps
cell division cycle 34 homolog, pseudogene (S. cerevisiae)
chr3_+_108383829 1.590 ENSMUST00000090561.3
ENSMUST00000102629.1
ENSMUST00000128089.1
Psrc1


proline/serine-rich coiled-coil 1


chr19_+_54045182 1.514 ENSMUST00000036700.5
Adra2a
adrenergic receptor, alpha 2a
chr4_-_133602168 1.495 ENSMUST00000057311.3
Sfn
stratifin
chr6_-_49214954 1.479 ENSMUST00000031838.7
Igf2bp3
insulin-like growth factor 2 mRNA binding protein 3
chr7_-_140082246 1.456 ENSMUST00000166758.2
Caly
calcyon neuron-specific vesicular protein
chr18_-_46212595 1.455 ENSMUST00000037011.4
Trim36
tripartite motif-containing 36
chr9_+_74848437 1.419 ENSMUST00000161862.1
ENSMUST00000162089.1
ENSMUST00000160017.1
ENSMUST00000160950.1
Gm16551


Gm20649
predicted gene 16551


predicted gene 20649
chr13_-_56296551 1.412 ENSMUST00000021970.9
Cxcl14
chemokine (C-X-C motif) ligand 14
chr9_-_106199253 1.408 ENSMUST00000140761.1
Ppm1m
protein phosphatase 1M
chr18_+_35829798 1.383 ENSMUST00000060722.6
Cxxc5
CXXC finger 5
chr2_-_68472138 1.378 ENSMUST00000102715.3
Stk39
serine/threonine kinase 39
chr1_+_109982710 1.340 ENSMUST00000112701.1
Cdh7
cadherin 7, type 2
chr6_+_54039558 1.281 ENSMUST00000046856.7
Chn2
chimerin (chimaerin) 2
chr5_-_100719675 1.259 ENSMUST00000112908.1
ENSMUST00000045617.8
Hpse

heparanase

chr11_-_120598346 1.248 ENSMUST00000026125.2
Alyref
Aly/REF export factor
chr10_-_29535857 1.236 ENSMUST00000092623.3
Rspo3
R-spondin 3 homolog (Xenopus laevis)
chr10_+_56377300 1.224 ENSMUST00000068581.7
Gja1
gap junction protein, alpha 1
chr7_-_74554474 1.209 ENSMUST00000134539.1
ENSMUST00000026897.7
ENSMUST00000098371.2
Slco3a1


solute carrier organic anion transporter family, member 3a1


chr5_-_22344690 1.198 ENSMUST00000062372.7
ENSMUST00000161356.1
Reln

reelin

chr8_-_80739497 1.190 ENSMUST00000043359.8
Smarca5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr11_-_28583995 1.185 ENSMUST00000146385.2
Ccdc85a
coiled-coil domain containing 85A
chr1_+_132316112 1.172 ENSMUST00000082125.5
ENSMUST00000072177.7
Nuak2

NUAK family, SNF1-like kinase, 2

chrX_+_100625737 1.161 ENSMUST00000048962.3
Kif4
kinesin family member 4
chr10_+_96136603 1.134 ENSMUST00000074615.6
Gm5426
predicted pseudogene 5426
chr8_+_83389846 1.127 ENSMUST00000002259.6
Clgn
calmegin
chr1_-_178337774 1.099 ENSMUST00000037748.7
Hnrnpu
heterogeneous nuclear ribonucleoprotein U
chr15_-_38300693 1.071 ENSMUST00000074043.5
Klf10
Kruppel-like factor 10
chr19_+_38930909 1.069 ENSMUST00000025965.5
Hells
helicase, lymphoid specific
chr1_-_172329261 1.024 ENSMUST00000062387.2
Kcnj9
potassium inwardly-rectifying channel, subfamily J, member 9
chr5_-_24329556 1.004 ENSMUST00000115098.2
Kcnh2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr8_-_105637403 1.001 ENSMUST00000182046.1
Gm5914
predicted gene 5914
chr7_+_31059342 1.001 ENSMUST00000039775.7
Lgi4
leucine-rich repeat LGI family, member 4
chr16_-_76403673 0.998 ENSMUST00000052867.7
Gm9843
predicted gene 9843
chr4_-_19708922 0.986 ENSMUST00000108246.2
Wwp1
WW domain containing E3 ubiquitin protein ligase 1
chr15_-_63997969 0.983 ENSMUST00000164532.1
Fam49b
family with sequence similarity 49, member B
chr9_-_59146210 0.979 ENSMUST00000085631.2
Gm7589
predicted gene 7589
chr3_+_126597299 0.977 ENSMUST00000106400.2
ENSMUST00000106401.1
Camk2d

calcium/calmodulin-dependent protein kinase II, delta

chr13_-_99900645 0.967 ENSMUST00000022150.6
Cartpt
CART prepropeptide
chr9_-_44320229 0.946 ENSMUST00000065080.8
C2cd2l
C2 calcium-dependent domain containing 2-like
chr6_+_50110186 0.944 ENSMUST00000166318.1
ENSMUST00000036236.8
ENSMUST00000036225.8
Mpp6


membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)


chr3_-_37125943 0.942 ENSMUST00000029275.5
Il2
interleukin 2
chr15_+_16778101 0.938 ENSMUST00000026432.6
Cdh9
cadherin 9
chr7_-_141443989 0.937 ENSMUST00000026580.5
Lrdd
leucine-rich and death domain containing
chr10_-_86705485 0.937 ENSMUST00000020238.7
Hsp90b1
heat shock protein 90, beta (Grp94), member 1
chr2_-_73214409 0.924 ENSMUST00000028517.6
Ola1
Obg-like ATPase 1
chr12_+_53248677 0.914 ENSMUST00000101432.2
Npas3
neuronal PAS domain protein 3
chr2_-_53191214 0.909 ENSMUST00000076313.6
ENSMUST00000125243.1
Prpf40a

PRP40 pre-mRNA processing factor 40 homolog A (yeast)

chr4_+_129287614 0.897 ENSMUST00000102599.3
Sync
syncoilin
chr19_-_23273893 0.896 ENSMUST00000087556.5
Smc5
structural maintenance of chromosomes 5
chr4_+_33031371 0.878 ENSMUST00000124992.1
Ube2j1
ubiquitin-conjugating enzyme E2J 1
chr3_-_119783262 0.876 ENSMUST00000029780.7
Ptbp2
polypyrimidine tract binding protein 2
chr15_-_9748777 0.862 ENSMUST00000159368.1
ENSMUST00000159093.1
ENSMUST00000162780.1
ENSMUST00000160236.1
ENSMUST00000041840.7
Spef2




sperm flagellar 2




chr11_+_116280939 0.852 ENSMUST00000055872.2
Galr2
galanin receptor 2
chr2_-_148045891 0.842 ENSMUST00000109964.1
Foxa2
forkhead box A2
chrX_-_147554050 0.841 ENSMUST00000112819.2
ENSMUST00000136789.1
Lrch2

leucine-rich repeats and calponin homology (CH) domain containing 2

chr7_-_130573118 0.832 ENSMUST00000159694.1
Nsmce4a
non-SMC element 4 homolog A (S. cerevisiae)
chr1_-_105356658 0.830 ENSMUST00000058688.5
ENSMUST00000172299.1
Rnf152

ring finger protein 152

chr18_+_15832772 0.824 ENSMUST00000079733.5
Gm10036
predicted gene 10036
chr16_+_18348181 0.820 ENSMUST00000115614.2
ENSMUST00000115613.1
ENSMUST00000090103.3
Arvcf


armadillo repeat gene deleted in velo-cardio-facial syndrome


chr4_+_108460000 0.810 ENSMUST00000097925.2
Zcchc11
zinc finger, CCHC domain containing 11
chr10_-_114801364 0.782 ENSMUST00000061632.7
Trhde
TRH-degrading enzyme
chr5_+_43233928 0.780 ENSMUST00000114066.1
ENSMUST00000114065.1
Cpeb2

cytoplasmic polyadenylation element binding protein 2

chr6_+_54039935 0.774 ENSMUST00000114403.1
Chn2
chimerin (chimaerin) 2
chr6_+_35252692 0.770 ENSMUST00000130875.1
1810058I24Rik
RIKEN cDNA 1810058I24 gene
chr3_+_96629919 0.766 ENSMUST00000048915.6
Rbm8a
RNA binding motif protein 8a
chr17_-_46440099 0.765 ENSMUST00000166852.1
Gm5093
predicted gene 5093
chr3_-_146839365 0.765 ENSMUST00000084614.3
Gm10288
predicted gene 10288
chr4_-_123750236 0.761 ENSMUST00000102636.3
Akirin1
akirin 1
chr12_-_21417356 0.760 ENSMUST00000103002.1
Ywhaq
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
chr8_-_47675556 0.755 ENSMUST00000125536.1
Ing2
inhibitor of growth family, member 2
chrX_-_57392962 0.749 ENSMUST00000114730.1
Rbmx
RNA binding motif protein, X chromosome
chr3_-_100489324 0.744 ENSMUST00000061455.8
Fam46c
family with sequence similarity 46, member C
chr9_-_95845215 0.731 ENSMUST00000093800.2
Pls1
plastin 1 (I-isoform)
chr2_+_121456963 0.722 ENSMUST00000126764.1
Hypk
huntingtin interacting protein K
chr7_+_81858993 0.720 ENSMUST00000041890.1
Tm6sf1
transmembrane 6 superfamily member 1
chr6_+_50110837 0.720 ENSMUST00000167628.1
Mpp6
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
chr10_+_128821745 0.719 ENSMUST00000105230.2
Sarnp
SAP domain containing ribonucleoprotein
chrX_+_36795642 0.715 ENSMUST00000016463.3
Slc25a5
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5
chr6_+_35252654 0.709 ENSMUST00000152147.1
1810058I24Rik
RIKEN cDNA 1810058I24 gene
chrX_-_73458990 0.709 ENSMUST00000033737.8
ENSMUST00000077243.4
Haus7

HAUS augmin-like complex, subunit 7

chr19_-_4439388 0.706 ENSMUST00000117462.1
ENSMUST00000048197.3
Rhod

ras homolog gene family, member D

chrX_-_51205773 0.704 ENSMUST00000114875.1
Mbnl3
muscleblind-like 3 (Drosophila)
chr2_+_27079371 0.693 ENSMUST00000091233.6
Adamtsl2
ADAMTS-like 2
chrX_+_42151002 0.690 ENSMUST00000123245.1
Stag2
stromal antigen 2
chr3_-_65529355 0.680 ENSMUST00000099076.3
4931440P22Rik
RIKEN cDNA 4931440P22 gene
chr11_+_78032274 0.679 ENSMUST00000021187.5
Dhrs13
dehydrogenase/reductase (SDR family) member 13
chr4_+_148000722 0.672 ENSMUST00000103230.4
Nppa
natriuretic peptide type A
chr11_-_22286795 0.671 ENSMUST00000109563.2
ENSMUST00000180360.1
Ehbp1

EH domain binding protein 1

chr9_-_96437434 0.670 ENSMUST00000070500.2
BC043934
cDNA sequence BC043934
chr19_+_38931008 0.667 ENSMUST00000145051.1
Hells
helicase, lymphoid specific
chr3_+_121426495 0.662 ENSMUST00000029773.8
Cnn3
calponin 3, acidic
chr7_-_102100227 0.660 ENSMUST00000106937.1
Art5
ADP-ribosyltransferase 5
chr5_-_77115145 0.657 ENSMUST00000081964.5
Hopx
HOP homeobox
chr9_+_107547288 0.656 ENSMUST00000010188.7
Zmynd10
zinc finger, MYND domain containing 10
chr3_-_75556759 0.645 ENSMUST00000162138.1
ENSMUST00000029424.5
ENSMUST00000161137.1
Pdcd10


programmed cell death 10


chr4_-_40948196 0.641 ENSMUST00000030125.4
ENSMUST00000108089.1
Bag1

BCL2-associated athanogene 1

chr8_+_5639514 0.637 ENSMUST00000051687.3
Gm1840
predicted gene 1840
chr9_-_35558522 0.637 ENSMUST00000034612.5
Ddx25
DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
chr9_-_48480540 0.636 ENSMUST00000034524.3
Rexo2
REX2, RNA exonuclease 2 homolog (S. cerevisiae)
chr1_+_91366412 0.636 ENSMUST00000086861.5
Fam132b
family with sequence similarity 132, member B
chr1_-_75219245 0.632 ENSMUST00000079464.6
Tuba4a
tubulin, alpha 4A
chr14_-_57104693 0.620 ENSMUST00000055698.7
Gjb2
gap junction protein, beta 2
chr11_+_70657687 0.610 ENSMUST00000134087.1
ENSMUST00000170716.1
Eno3

enolase 3, beta muscle

chr11_+_118428493 0.609 ENSMUST00000017590.2
C1qtnf1
C1q and tumor necrosis factor related protein 1
chrX_-_57393020 0.608 ENSMUST00000143310.1
ENSMUST00000098470.2
ENSMUST00000114726.1
Rbmx


RNA binding motif protein, X chromosome


chr8_-_105637350 0.594 ENSMUST00000182863.1
Gm5914
predicted gene 5914
chr3_+_90062781 0.594 ENSMUST00000029551.2
1700094D03Rik
RIKEN cDNA 1700094D03 gene
chrX_-_100625901 0.593 ENSMUST00000059099.6
Pdzd11
PDZ domain containing 11
chr1_+_63273261 0.580 ENSMUST00000114132.1
ENSMUST00000126932.1
Zdbf2

zinc finger, DBF-type containing 2

chr17_+_46681038 0.577 ENSMUST00000002845.6
Mea1
male enhanced antigen 1
chrX_-_49797700 0.576 ENSMUST00000033442.7
ENSMUST00000114891.1
Igsf1

immunoglobulin superfamily, member 1

chr11_+_78032346 0.574 ENSMUST00000122342.1
ENSMUST00000092881.3
Dhrs13

dehydrogenase/reductase (SDR family) member 13

chr7_+_28982832 0.573 ENSMUST00000085835.6
Map4k1
mitogen-activated protein kinase kinase kinase kinase 1
chr18_+_82914632 0.564 ENSMUST00000071233.6
Zfp516
zinc finger protein 516
chr11_+_98446826 0.551 ENSMUST00000019456.4
Grb7
growth factor receptor bound protein 7
chr12_-_88286055 0.550 ENSMUST00000179741.1
Gm7104
predicted gene 7104
chr6_+_35252724 0.543 ENSMUST00000136110.1
1810058I24Rik
RIKEN cDNA 1810058I24 gene
chr2_-_131187282 0.537 ENSMUST00000028801.1
Spef1
sperm flagellar 1
chr15_-_89425856 0.536 ENSMUST00000109313.2
Cpt1b
carnitine palmitoyltransferase 1b, muscle
chr3_+_36552600 0.521 ENSMUST00000029269.5
ENSMUST00000136890.1
Exosc9

exosome component 9

chr11_+_83662579 0.517 ENSMUST00000019074.3
Ccl4
chemokine (C-C motif) ligand 4
chrX_-_51205990 0.516 ENSMUST00000114876.2
Mbnl3
muscleblind-like 3 (Drosophila)
chr3_-_95306794 0.513 ENSMUST00000107183.1
ENSMUST00000164406.1
ENSMUST00000123365.1
Anxa9


annexin A9


chr9_-_67760208 0.505 ENSMUST00000068526.5
M5C1000I18Rik
RIKEN cDNA M5C1000I18 gene
chr4_+_84884418 0.502 ENSMUST00000169371.2
Cntln
centlein, centrosomal protein
chr2_-_119208767 0.496 ENSMUST00000038439.3
Dnajc17
DnaJ (Hsp40) homolog, subfamily C, member 17
chr11_+_72607221 0.496 ENSMUST00000021148.6
ENSMUST00000138247.1
Ube2g1

ubiquitin-conjugating enzyme E2G 1

chr15_-_83033294 0.494 ENSMUST00000100377.4
Nfam1
Nfat activating molecule with ITAM motif 1
chr12_-_31634592 0.492 ENSMUST00000020979.7
ENSMUST00000177962.1
Bcap29

B cell receptor associated protein 29

chrX_+_169685191 0.489 ENSMUST00000112104.1
ENSMUST00000112107.1
Mid1

midline 1

chr2_-_73214323 0.484 ENSMUST00000100015.4
Ola1
Obg-like ATPase 1
chr5_+_113490447 0.479 ENSMUST00000094452.3
Wscd2
WSC domain containing 2
chr9_+_37528071 0.479 ENSMUST00000002011.7
Esam
endothelial cell-specific adhesion molecule
chr4_+_33031527 0.473 ENSMUST00000029944.6
Ube2j1
ubiquitin-conjugating enzyme E2J 1
chr4_+_117096049 0.472 ENSMUST00000030443.5
Ptch2
patched homolog 2
chr10_+_86705811 0.471 ENSMUST00000061458.7
ENSMUST00000075632.6
BC030307

cDNA sequence BC030307

chr4_-_108833608 0.471 ENSMUST00000102742.4
Btf3l4
basic transcription factor 3-like 4
chr12_-_35534973 0.467 ENSMUST00000116436.2
Ahr
aryl-hydrocarbon receptor
chr3_+_75557530 0.466 ENSMUST00000161776.1
ENSMUST00000029423.8
Serpini1

serine (or cysteine) peptidase inhibitor, clade I, member 1

chr7_-_4684963 0.463 ENSMUST00000079970.4
Hspbp1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr10_-_80590292 0.460 ENSMUST00000003436.5
Abhd17a
abhydrolase domain containing 17A
chr7_-_74554726 0.456 ENSMUST00000107453.1
Slco3a1
solute carrier organic anion transporter family, member 3a1
chr11_-_96943945 0.454 ENSMUST00000107629.1
ENSMUST00000018803.5
Pnpo

pyridoxine 5'-phosphate oxidase

chr1_-_51915968 0.447 ENSMUST00000046390.7
Myo1b
myosin IB
chr15_+_98634743 0.439 ENSMUST00000003442.7
Cacnb3
calcium channel, voltage-dependent, beta 3 subunit
chr8_+_83389878 0.435 ENSMUST00000109831.2
Clgn
calmegin
chr19_+_45015168 0.432 ENSMUST00000039016.6
Lzts2
leucine zipper, putative tumor suppressor 2
chr7_+_25681158 0.431 ENSMUST00000108403.3
B9d2
B9 protein domain 2
chr1_-_125912160 0.430 ENSMUST00000159417.1
Lypd1
Ly6/Plaur domain containing 1
chr4_+_126677630 0.425 ENSMUST00000030642.2
Psmb2
proteasome (prosome, macropain) subunit, beta type 2
chr10_-_77113928 0.423 ENSMUST00000149744.1
Col18a1
collagen, type XVIII, alpha 1
chr7_+_113513829 0.419 ENSMUST00000033018.8
Far1
fatty acyl CoA reductase 1
chr9_-_62537036 0.418 ENSMUST00000048043.5
Coro2b
coronin, actin binding protein, 2B
chr4_-_108833544 0.415 ENSMUST00000102740.1
ENSMUST00000102741.1
Btf3l4

basic transcription factor 3-like 4

chr7_+_140125651 0.413 ENSMUST00000026537.5
ENSMUST00000097967.3
Paox

polyamine oxidase (exo-N4-amino)

chr1_+_66364623 0.409 ENSMUST00000077355.5
ENSMUST00000114012.1
Map2

microtubule-associated protein 2

chr2_-_148046896 0.405 ENSMUST00000172928.1
ENSMUST00000047315.3
Foxa2

forkhead box A2

chr4_+_115059507 0.400 ENSMUST00000162489.1
Tal1
T cell acute lymphocytic leukemia 1
chr6_-_119330723 0.398 ENSMUST00000068351.7
Lrtm2
leucine-rich repeats and transmembrane domains 2
chr1_+_171329569 0.395 ENSMUST00000142063.1
ENSMUST00000129116.1
Dedd

death effector domain-containing

chr1_-_74601345 0.387 ENSMUST00000136078.1
ENSMUST00000132081.1
ENSMUST00000113721.1
ENSMUST00000027357.5
Rnf25



ring finger protein 25



chr11_-_3371307 0.386 ENSMUST00000101642.3
ENSMUST00000101640.3
Limk2

LIM motif-containing protein kinase 2

chr5_-_142906702 0.384 ENSMUST00000167721.1
ENSMUST00000163829.1
ENSMUST00000100497.4
Actb


actin, beta


chr18_+_61555258 0.383 ENSMUST00000165123.1
Csnk1a1
casein kinase 1, alpha 1
chr11_-_48946148 0.381 ENSMUST00000104958.1
Psme2b
protease (prosome, macropain) activator subunit 2B
chr19_+_45015198 0.379 ENSMUST00000179108.1
Lzts2
leucine zipper, putative tumor suppressor 2
chrX_+_20425688 0.376 ENSMUST00000115384.2
Phf16
PHD finger protein 16
chr11_+_70700606 0.374 ENSMUST00000137119.2
Kif1c
kinesin family member 1C
chr14_+_65266701 0.357 ENSMUST00000169656.1
Fbxo16
F-box protein 16
chr11_+_69965396 0.355 ENSMUST00000018713.6
Cldn7
claudin 7
chr15_-_27681498 0.353 ENSMUST00000100739.3
Fam105a
family with sequence similarity 105, member A
chrX_+_74313014 0.353 ENSMUST00000114160.1
Fam50a
family with sequence similarity 50, member A
chr5_-_17888884 0.342 ENSMUST00000169095.1
Cd36
CD36 antigen

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.0 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
1.0 4.9 GO:0035262 gonad morphogenesis(GO:0035262)
1.0 4.9 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.6 1.9 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.6 1.9 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.6 2.3 GO:0030091 protein repair(GO:0030091)
0.5 2.4 GO:0007386 compartment pattern specification(GO:0007386)
0.5 3.8 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.5 1.4 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016) regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.4 1.3 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.4 1.2 GO:0045014 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594)
0.4 1.2 GO:0003104 positive regulation of glomerular filtration(GO:0003104) cell communication by chemical coupling(GO:0010643)
0.4 3.6 GO:0010587 miRNA catabolic process(GO:0010587)
0.4 1.9 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.4 1.5 GO:0035624 receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.4 4.1 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.4 1.1 GO:2000373 regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.3 1.0 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.3 1.2 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.3 0.9 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.3 3.8 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.3 1.7 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.3 1.0 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.2 1.7 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.2 0.7 GO:0001951 intestinal D-glucose absorption(GO:0001951) terminal web assembly(GO:1902896)
0.2 1.6 GO:1902302 regulation of potassium ion export(GO:1902302)
0.2 0.2 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.2 0.6 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.2 0.9 GO:1902608 regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.2 0.5 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.2 1.2 GO:0016584 nucleosome positioning(GO:0016584)
0.2 1.5 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839) keratinization(GO:0031424)
0.2 0.5 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.2 0.5 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
0.2 0.8 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 0.4 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.1 1.4 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 0.4 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.1 0.4 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.1 1.7 GO:0006857 oligopeptide transport(GO:0006857)
0.1 0.6 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.5 GO:0009957 epidermal cell fate specification(GO:0009957)
0.1 0.5 GO:0040010 positive regulation of growth rate(GO:0040010)
0.1 1.7 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.3 GO:0070543 response to linoleic acid(GO:0070543)
0.1 0.1 GO:0097360 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.1 0.3 GO:0007521 regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003256) muscle cell fate determination(GO:0007521) mammary placode formation(GO:0060596)
0.1 0.6 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.1 0.3 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
0.1 0.3 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.1 0.7 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.1 1.1 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 0.3 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.1 0.6 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.3 GO:0006106 fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533) alditol biosynthetic process(GO:0019401)
0.1 0.7 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.1 0.3 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.1 0.2 GO:1904152 regulation of retrograde protein transport, ER to cytosol(GO:1904152)
0.1 0.9 GO:0071318 cellular response to ATP(GO:0071318)
0.1 2.2 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.1 0.2 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.1 1.2 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1 0.5 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 0.6 GO:0016264 gap junction assembly(GO:0016264)
0.1 1.6 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.1 0.6 GO:2000858 mineralocorticoid secretion(GO:0035931) aldosterone secretion(GO:0035932) regulation of mineralocorticoid secretion(GO:2000855) positive regulation of mineralocorticoid secretion(GO:2000857) regulation of aldosterone secretion(GO:2000858) positive regulation of aldosterone secretion(GO:2000860)
0.1 0.7 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 0.2 GO:0007403 glial cell fate determination(GO:0007403)
0.1 0.9 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 0.7 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 0.8 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.1 0.5 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 0.3 GO:0002339 B cell selection(GO:0002339)
0.1 1.0 GO:0001916 positive regulation of T cell mediated cytotoxicity(GO:0001916)
0.1 0.1 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.1 1.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 1.5 GO:0007340 acrosome reaction(GO:0007340)
0.1 0.7 GO:0036159 outer dynein arm assembly(GO:0036158) inner dynein arm assembly(GO:0036159)
0.1 0.1 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.1 0.8 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 0.3 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.1 0.4 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.1 0.5 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.3 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.1 0.3 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 0.7 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.1 2.2 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 1.9 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.0 0.9 GO:0042711 maternal behavior(GO:0042711)
0.0 0.3 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 1.0 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.5 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.3 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.4 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 1.2 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.2 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.2 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.9 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.4 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.2 GO:0045630 positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.0 0.9 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.2 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 1.0 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.3 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.1 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 0.6 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0051890 regulation of cardioblast differentiation(GO:0051890)
0.0 0.4 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 0.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 1.6 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.8 GO:0043171 peptide catabolic process(GO:0043171)
0.0 1.0 GO:0045103 intermediate filament-based process(GO:0045103)
0.0 0.9 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.0 0.5 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.0 0.3 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.7 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 0.6 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.3 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.2 GO:0036506 maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 1.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 1.3 GO:0051028 mRNA transport(GO:0051028)
0.0 0.8 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.5 GO:0010107 potassium ion import(GO:0010107)
0.0 0.4 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.1 GO:0001575 globoside metabolic process(GO:0001575)
0.0 0.1 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.2 GO:0007602 phototransduction(GO:0007602)
0.0 0.0 GO:2001187 positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.0 0.1 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.6 GO:0009409 response to cold(GO:0009409)
0.0 0.8 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 0.2 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.8 GO:0034766 negative regulation of ion transmembrane transport(GO:0034766)
0.0 0.5 GO:1901998 toxin transport(GO:1901998)
0.0 0.1 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.8 GO:2001022 positive regulation of response to DNA damage stimulus(GO:2001022)
0.0 0.2 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 1.0 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.3 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.1 GO:0032366 intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.0 0.5 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.5 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 1.4 GO:0046034 ATP metabolic process(GO:0046034)
0.0 0.3 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.9 GO:0031638 zymogen activation(GO:0031638)
0.0 1.4 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.3 GO:0002177 manchette(GO:0002177)
0.3 3.9 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.3 0.9 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.3 0.9 GO:0035061 interchromatin granule(GO:0035061)
0.3 1.0 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.2 1.4 GO:0044530 supraspliceosomal complex(GO:0044530)
0.2 1.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.2 0.8 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 0.7 GO:1990357 terminal web(GO:1990357)
0.1 0.4 GO:0033193 Lsd1/2 complex(GO:0033193)
0.1 1.8 GO:0005922 connexon complex(GO:0005922)
0.1 4.4 GO:0043194 axon initial segment(GO:0043194)
0.1 0.8 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.2 GO:0097526 U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.1 0.7 GO:0071817 MMXD complex(GO:0071817)
0.1 0.5 GO:0031983 vesicle lumen(GO:0031983)
0.1 0.5 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.3 GO:0005940 septin ring(GO:0005940)
0.1 0.7 GO:0070652 HAUS complex(GO:0070652)
0.1 1.2 GO:0016589 NURF complex(GO:0016589)
0.1 0.7 GO:0042629 mast cell granule(GO:0042629)
0.1 0.3 GO:0035339 SPOTS complex(GO:0035339)
0.1 4.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 0.6 GO:0033391 chromatoid body(GO:0033391)
0.1 0.3 GO:0019815 B cell receptor complex(GO:0019815)
0.1 4.5 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.9 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 2.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.5 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 1.0 GO:0000346 transcription export complex(GO:0000346)
0.0 0.2 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.4 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.9 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.2 GO:0097227 sperm annulus(GO:0097227)
0.0 1.2 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 2.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 1.6 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 2.3 GO:0005604 basement membrane(GO:0005604)
0.0 0.7 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.2 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 1.2 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.8 GO:0005581 collagen trimer(GO:0005581)
0.0 0.4 GO:0005839 proteasome core complex(GO:0005839)
0.0 1.0 GO:0005882 intermediate filament(GO:0005882)
0.0 0.2 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.4 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.1 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.7 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 2.1 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.6 1.9 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.6 4.9 GO:0031432 titin binding(GO:0031432)
0.5 1.5 GO:0004936 alpha-adrenergic receptor activity(GO:0004936) epinephrine binding(GO:0051379)
0.4 2.3 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.3 1.2 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075) gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.3 0.9 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.3 1.1 GO:0034046 poly(G) binding(GO:0034046)
0.3 2.9 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.2 1.7 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.2 0.9 GO:0004966 galanin receptor activity(GO:0004966)
0.2 1.9 GO:0043237 laminin-1 binding(GO:0043237)
0.2 1.3 GO:0045545 syndecan binding(GO:0045545)
0.2 1.0 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 1.0 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.2 1.2 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.2 0.9 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.2 1.5 GO:0032051 clathrin light chain binding(GO:0032051)
0.2 0.7 GO:0050436 microfibril binding(GO:0050436)
0.2 1.0 GO:0023029 MHC class Ib protein binding(GO:0023029)
0.2 0.8 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.2 0.5 GO:0005119 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158)
0.2 1.4 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.4 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.1 0.4 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.1 5.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 0.9 GO:0043559 insulin binding(GO:0043559)
0.1 0.9 GO:0046790 virion binding(GO:0046790)
0.1 0.3 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.6 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.1 0.3 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.1 0.3 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.1 0.6 GO:0005243 gap junction channel activity(GO:0005243)
0.1 1.7 GO:0070410 co-SMAD binding(GO:0070410)
0.1 1.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 3.8 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 2.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.7 GO:0050733 RS domain binding(GO:0050733)
0.1 0.7 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 0.6 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 2.4 GO:0005112 Notch binding(GO:0005112)
0.1 1.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.7 GO:0031996 thioesterase binding(GO:0031996)
0.1 1.9 GO:0008009 chemokine activity(GO:0008009)
0.1 0.6 GO:0034711 inhibin binding(GO:0034711)
0.1 1.5 GO:0030506 ankyrin binding(GO:0030506)
0.1 0.3 GO:0015166 polyol transmembrane transporter activity(GO:0015166) glycerol transmembrane transporter activity(GO:0015168)
0.1 0.5 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 0.5 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.1 1.5 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.3 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 1.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.4 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 2.0 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 0.3 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.4 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.2 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 1.3 GO:0031491 nucleosome binding(GO:0031491)
0.0 1.0 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.7 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.0 0.2 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.1 GO:0031752 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.0 0.8 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361) activin-activated receptor activity(GO:0017002)
0.0 0.5 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 1.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.3 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0034235 GPI anchor binding(GO:0034235)
0.0 1.2 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.0 3.2 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 1.7 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.2 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0015250 water channel activity(GO:0015250)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.3 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.3 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 0.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.9 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 1.2 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 2.0 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 2.4 GO:0004386 helicase activity(GO:0004386)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 2.2 GO:0001047 core promoter binding(GO:0001047)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.5 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.6 GO:0003777 microtubule motor activity(GO:0003777)
0.0 5.3 GO:0005198 structural molecule activity(GO:0005198)
0.0 1.3 GO:0047485 protein N-terminus binding(GO:0047485)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.3 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 4.6 NABA_COLLAGENS Genes encoding collagen proteins
0.1 1.9 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.1 3.5 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 1.3 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 0.9 PID_IL27_PATHWAY IL27-mediated signaling events
0.0 1.2 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.6 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.6 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.0 1.0 ST_G_ALPHA_I_PATHWAY G alpha i Pathway
0.0 0.8 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 1.7 PID_TCR_PATHWAY TCR signaling in naïve CD4+ T cells
0.0 1.2 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 0.2 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 3.4 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.9 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 1.3 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 1.5 PID_FGF_PATHWAY FGF signaling pathway
0.0 0.4 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.6 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.5 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.8 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 0.4 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.5 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 0.2 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 0.3 PID_BCR_5PATHWAY BCR signaling pathway
0.0 0.7 PID_PLK1_PATHWAY PLK1 signaling events
0.0 1.1 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.5 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.3 PID_SHP2_PATHWAY SHP2 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.2 1.8 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.1 4.3 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.1 3.3 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 1.5 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 0.9 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 4.3 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 2.3 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.6 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.1 1.3 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.1 0.3 REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRONLESS_TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.1 0.4 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 0.5 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 1.7 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.2 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.7 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.6 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.2 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 2.2 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 8.8 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.0 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.6 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.0 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.7 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 3.2 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.0 1.2 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.2 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.1 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.6 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.7 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.7 REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.6 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.4 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.3 REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.3 REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 0.2 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.0 0.2 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.5 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.1 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.8 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.8 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.1 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL