Motif ID: Gata5
Z-value: 0.793

Transcription factors associated with Gata5:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Gata5 | ENSMUSG00000015627.5 | Gata5 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
4.6 | 22.9 | GO:0015671 | oxygen transport(GO:0015671) |
0.6 | 1.8 | GO:0046462 | monoacylglycerol metabolic process(GO:0046462) |
0.6 | 2.8 | GO:1903215 | negative regulation of protein targeting to mitochondrion(GO:1903215) |
0.5 | 2.3 | GO:0060849 | regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849) |
0.2 | 0.6 | GO:0001830 | trophectodermal cell fate commitment(GO:0001830) |
0.2 | 0.6 | GO:0006436 | tryptophanyl-tRNA aminoacylation(GO:0006436) |
0.1 | 0.4 | GO:0019401 | alditol biosynthetic process(GO:0019401) |
0.1 | 0.4 | GO:0060023 | soft palate development(GO:0060023) |
0.1 | 3.1 | GO:0045663 | positive regulation of myoblast differentiation(GO:0045663) |
0.1 | 0.3 | GO:2000620 | positive regulation of histone H4-K16 acetylation(GO:2000620) |
0.1 | 0.8 | GO:0002862 | negative regulation of inflammatory response to antigenic stimulus(GO:0002862) |
0.1 | 0.7 | GO:0036072 | intramembranous ossification(GO:0001957) direct ossification(GO:0036072) |
0.1 | 1.7 | GO:0046069 | cGMP catabolic process(GO:0046069) |
0.1 | 0.3 | GO:0072488 | ammonium transmembrane transport(GO:0072488) |
0.1 | 4.0 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
0.1 | 0.3 | GO:0016068 | regulation of type I hypersensitivity(GO:0001810) positive regulation of type I hypersensitivity(GO:0001812) type I hypersensitivity(GO:0016068) |
0.1 | 0.8 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
0.1 | 0.2 | GO:1902605 | heterotrimeric G-protein complex assembly(GO:1902605) |
0.1 | 0.2 | GO:0046098 | purine nucleobase salvage(GO:0043096) guanine metabolic process(GO:0046098) hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101) |
0.1 | 0.4 | GO:0035878 | nail development(GO:0035878) |
0.1 | 0.2 | GO:1903225 | regulation of endodermal cell fate specification(GO:0042663) negative regulation of endodermal cell differentiation(GO:1903225) |
0.1 | 0.4 | GO:0030277 | maintenance of gastrointestinal epithelium(GO:0030277) |
0.1 | 0.6 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
0.1 | 0.6 | GO:0032693 | negative regulation of interleukin-10 production(GO:0032693) |
0.1 | 0.2 | GO:0019276 | UDP-N-acetylgalactosamine metabolic process(GO:0019276) |
0.1 | 0.6 | GO:0034242 | negative regulation of syncytium formation by plasma membrane fusion(GO:0034242) |
0.1 | 0.2 | GO:0072592 | integrin biosynthetic process(GO:0045112) regulation of integrin biosynthetic process(GO:0045113) oxygen metabolic process(GO:0072592) |
0.1 | 0.3 | GO:0045657 | positive regulation of monocyte differentiation(GO:0045657) |
0.0 | 0.4 | GO:0061368 | maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368) |
0.0 | 0.3 | GO:0032346 | positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349) leading edge cell differentiation(GO:0035026) regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298) |
0.0 | 0.6 | GO:0046485 | ether lipid metabolic process(GO:0046485) |
0.0 | 0.3 | GO:0006729 | tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146) |
0.0 | 0.1 | GO:0098968 | neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968) |
0.0 | 0.2 | GO:0042866 | pyruvate biosynthetic process(GO:0042866) |
0.0 | 0.1 | GO:0002430 | complement receptor mediated signaling pathway(GO:0002430) |
0.0 | 0.2 | GO:0070814 | hydrogen sulfide biosynthetic process(GO:0070814) |
0.0 | 0.3 | GO:0046543 | development of secondary female sexual characteristics(GO:0046543) |
0.0 | 0.4 | GO:0006517 | protein deglycosylation(GO:0006517) |
0.0 | 1.8 | GO:0045773 | positive regulation of axon extension(GO:0045773) |
0.0 | 0.3 | GO:0031468 | nuclear envelope reassembly(GO:0031468) |
0.0 | 0.3 | GO:0071763 | nuclear membrane organization(GO:0071763) |
0.0 | 0.4 | GO:0044406 | adhesion of symbiont to host(GO:0044406) |
0.0 | 0.1 | GO:0046013 | regulation of T cell homeostatic proliferation(GO:0046013) |
0.0 | 0.0 | GO:0032499 | detection of peptidoglycan(GO:0032499) |
0.0 | 1.1 | GO:1902653 | cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653) |
0.0 | 0.5 | GO:1902043 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043) |
0.0 | 0.7 | GO:0048821 | erythrocyte development(GO:0048821) |
0.0 | 0.1 | GO:0090527 | actin filament reorganization(GO:0090527) |
0.0 | 2.1 | GO:0030177 | positive regulation of Wnt signaling pathway(GO:0030177) |
0.0 | 0.1 | GO:0046501 | protoporphyrinogen IX metabolic process(GO:0046501) |
0.0 | 0.1 | GO:0051490 | negative regulation of filopodium assembly(GO:0051490) |
0.0 | 0.0 | GO:2000616 | negative regulation of histone H3-K9 acetylation(GO:2000616) |
0.0 | 0.3 | GO:0015813 | L-glutamate transport(GO:0015813) |
0.0 | 0.3 | GO:0045722 | positive regulation of gluconeogenesis(GO:0045722) |
0.0 | 0.2 | GO:0050765 | negative regulation of phagocytosis(GO:0050765) |
0.0 | 0.1 | GO:0061343 | cell adhesion involved in heart morphogenesis(GO:0061343) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.8 | 22.5 | GO:0005833 | hemoglobin complex(GO:0005833) |
0.2 | 0.7 | GO:0005584 | collagen type I trimer(GO:0005584) |
0.1 | 0.3 | GO:0071008 | U2-type post-mRNA release spliceosomal complex(GO:0071008) |
0.1 | 0.3 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
0.1 | 0.3 | GO:0070531 | BRCA1-A complex(GO:0070531) |
0.1 | 0.8 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
0.1 | 0.2 | GO:0071438 | invadopodium membrane(GO:0071438) |
0.1 | 3.1 | GO:0044295 | axonal growth cone(GO:0044295) |
0.0 | 0.4 | GO:0071437 | invadopodium(GO:0071437) |
0.0 | 1.1 | GO:0005839 | proteasome core complex(GO:0005839) |
0.0 | 0.4 | GO:0030056 | hemidesmosome(GO:0030056) |
0.0 | 0.4 | GO:0032797 | SMN complex(GO:0032797) |
0.0 | 0.1 | GO:0034750 | Scrib-APC-beta-catenin complex(GO:0034750) |
0.0 | 0.4 | GO:0020005 | symbiont-containing vacuole membrane(GO:0020005) |
0.0 | 0.4 | GO:0031011 | Ino80 complex(GO:0031011) |
0.0 | 0.3 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
0.0 | 0.6 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.0 | 0.1 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
0.0 | 0.3 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
0.0 | 1.3 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
0.0 | 0.1 | GO:1990635 | proximal dendrite(GO:1990635) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
4.6 | 22.9 | GO:0005344 | oxygen transporter activity(GO:0005344) |
0.6 | 1.8 | GO:0003846 | 2-acylglycerol O-acyltransferase activity(GO:0003846) |
0.4 | 1.1 | GO:0004769 | steroid delta-isomerase activity(GO:0004769) |
0.2 | 1.7 | GO:0048101 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
0.2 | 0.6 | GO:0004830 | tryptophan-tRNA ligase activity(GO:0004830) |
0.2 | 2.3 | GO:0001972 | retinoic acid binding(GO:0001972) |
0.1 | 0.6 | GO:0047275 | glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275) |
0.1 | 0.4 | GO:0019002 | GMP binding(GO:0019002) |
0.1 | 0.5 | GO:0004427 | inorganic diphosphatase activity(GO:0004427) |
0.1 | 0.3 | GO:0004069 | L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) |
0.1 | 0.6 | GO:0016803 | ether hydrolase activity(GO:0016803) |
0.1 | 0.4 | GO:0004032 | alditol:NADP+ 1-oxidoreductase activity(GO:0004032) |
0.1 | 0.4 | GO:0038132 | neuregulin binding(GO:0038132) |
0.1 | 0.2 | GO:0030171 | voltage-gated proton channel activity(GO:0030171) |
0.1 | 0.2 | GO:0001729 | ceramide kinase activity(GO:0001729) |
0.1 | 0.2 | GO:0004743 | pyruvate kinase activity(GO:0004743) |
0.1 | 0.9 | GO:0001530 | lipopolysaccharide binding(GO:0001530) |
0.0 | 0.7 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
0.0 | 0.2 | GO:0001010 | transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) |
0.0 | 0.2 | GO:0008479 | queuine tRNA-ribosyltransferase activity(GO:0008479) |
0.0 | 0.8 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.0 | 0.1 | GO:0004875 | complement receptor activity(GO:0004875) |
0.0 | 0.3 | GO:0005314 | high-affinity glutamate transmembrane transporter activity(GO:0005314) |
0.0 | 0.1 | GO:0008192 | RNA guanylyltransferase activity(GO:0008192) |
0.0 | 0.1 | GO:0004385 | guanylate kinase activity(GO:0004385) |
0.0 | 0.3 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
0.0 | 0.3 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
0.0 | 0.2 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
0.0 | 0.3 | GO:0022842 | leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842) |
0.0 | 0.6 | GO:0050699 | WW domain binding(GO:0050699) |
0.0 | 0.3 | GO:0000030 | mannosyltransferase activity(GO:0000030) |
0.0 | 0.3 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
0.0 | 0.7 | GO:0020037 | heme binding(GO:0020037) |
0.0 | 0.3 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
0.0 | 1.2 | GO:0008080 | N-acetyltransferase activity(GO:0008080) |
0.0 | 1.4 | GO:0042626 | ATPase activity, coupled to transmembrane movement of substances(GO:0042626) |
0.0 | 0.4 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
0.0 | 0.3 | GO:0005521 | lamin binding(GO:0005521) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 3.1 | PID_HEDGEHOG_2PATHWAY | Signaling events mediated by the Hedgehog family |
0.1 | 2.8 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
0.1 | 0.4 | PID_INTEGRIN4_PATHWAY | Alpha6 beta4 integrin-ligand interactions |
0.0 | 0.7 | PID_LYMPH_ANGIOGENESIS_PATHWAY | VEGFR3 signaling in lymphatic endothelium |
0.0 | 0.6 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
0.0 | 0.9 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
0.0 | 1.1 | SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 3.1 | REACTOME_MYOGENESIS | Genes involved in Myogenesis |
0.1 | 1.7 | REACTOME_CGMP_EFFECTS | Genes involved in cGMP effects |
0.0 | 1.1 | REACTOME_CHOLESTEROL_BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
0.0 | 1.1 | REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
0.0 | 0.3 | REACTOME_GAP_JUNCTION_DEGRADATION | Genes involved in Gap junction degradation |
0.0 | 0.9 | REACTOME_ELONGATION_ARREST_AND_RECOVERY | Genes involved in Elongation arrest and recovery |
0.0 | 2.3 | REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
0.0 | 0.3 | REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
0.0 | 0.3 | REACTOME_METABOLISM_OF_POLYAMINES | Genes involved in Metabolism of polyamines |
0.0 | 1.1 | REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES | Genes involved in Cross-presentation of soluble exogenous antigens (endosomes) |
0.0 | 0.3 | REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
0.0 | 0.3 | REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
0.0 | 0.3 | REACTOME_KINESINS | Genes involved in Kinesins |
0.0 | 2.3 | REACTOME_SIGNALING_BY_RHO_GTPASES | Genes involved in Signaling by Rho GTPases |
0.0 | 0.3 | REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS | Genes involved in Amine compound SLC transporters |
0.0 | 0.4 | REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
0.0 | 0.3 | REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |