Motif ID: Sox11

Z-value: 0.456


Transcription factors associated with Sox11:

Gene SymbolEntrez IDGene Name
Sox11 ENSMUSG00000063632.5 Sox11

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox11mm10_v2_chr12_-_27342696_273427260.571.2e-04Click!


Activity profile for motif Sox11.

activity profile for motif Sox11


Sorted Z-values histogram for motif Sox11

Sorted Z-values for motif Sox11



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox11

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_16378231 2.081 ENSMUST00000082170.5
Fat3
FAT tumor suppressor homolog 3 (Drosophila)
chr5_+_14514918 1.483 ENSMUST00000030691.10
ENSMUST00000182407.1
Pclo

piccolo (presynaptic cytomatrix protein)

chr8_-_34965631 1.218 ENSMUST00000033929.4
Tnks
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr6_-_23248264 0.947 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr13_-_99516537 0.871 ENSMUST00000064762.4
Map1b
microtubule-associated protein 1B
chr6_-_60829826 0.865 ENSMUST00000163779.1
Snca
synuclein, alpha
chr11_+_69364010 0.808 ENSMUST00000166700.1
Gm17305
predicted gene, 17305
chr9_+_89909775 0.778 ENSMUST00000034912.4
ENSMUST00000034909.4
Rasgrf1

RAS protein-specific guanine nucleotide-releasing factor 1

chr5_-_131616599 0.648 ENSMUST00000161804.1
Auts2
autism susceptibility candidate 2
chr16_+_8830093 0.609 ENSMUST00000023150.5
1810013L24Rik
RIKEN cDNA 1810013L24 gene
chr17_+_43016536 0.609 ENSMUST00000024708.4
Tnfrsf21
tumor necrosis factor receptor superfamily, member 21
chr2_-_79456750 0.609 ENSMUST00000041099.4
Neurod1
neurogenic differentiation 1
chr7_+_70388305 0.608 ENSMUST00000080024.5
B130024G19Rik
RIKEN cDNA B130024G19 gene
chrX_+_85574018 0.586 ENSMUST00000048250.3
ENSMUST00000137438.1
ENSMUST00000146063.1
Tab3


TGF-beta activated kinase 1/MAP3K7 binding protein 3


chr19_-_46969474 0.585 ENSMUST00000086961.7
Nt5c2
5'-nucleotidase, cytosolic II
chr2_+_154548888 0.581 ENSMUST00000045116.4
ENSMUST00000109709.3
1700003F12Rik

RIKEN cDNA 1700003F12 gene

chr4_-_44072578 0.571 ENSMUST00000173383.1
Gne
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr14_-_52213379 0.551 ENSMUST00000140603.1
Chd8
chromodomain helicase DNA binding protein 8
chr11_+_24080664 0.516 ENSMUST00000118955.1
Bcl11a
B cell CLL/lymphoma 11A (zinc finger protein)
chr16_-_50330987 0.502 ENSMUST00000114488.1
Bbx
bobby sox homolog (Drosophila)
chr2_+_15055274 0.465 ENSMUST00000069870.3
Arl5b
ADP-ribosylation factor-like 5B
chr1_-_175491130 0.464 ENSMUST00000027812.5
Rgs7
regulator of G protein signaling 7
chr5_+_144100387 0.449 ENSMUST00000041804.7
Lmtk2
lemur tyrosine kinase 2
chr1_+_44119952 0.448 ENSMUST00000114709.2
Bivm
basic, immunoglobulin-like variable motif containing
chr10_+_24869982 0.448 ENSMUST00000092646.6
Med23
mediator complex subunit 23
chr11_+_4873951 0.432 ENSMUST00000038570.2
Nipsnap1
4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1 (C. elegans)
chr2_+_3114220 0.416 ENSMUST00000072955.5
Fam171a1
family with sequence similarity 171, member A1
chr6_-_42693087 0.398 ENSMUST00000121083.1
Fam115a
family with sequence similarity 115, member A
chr9_+_32116040 0.388 ENSMUST00000174641.1
Arhgap32
Rho GTPase activating protein 32
chr15_+_76797628 0.382 ENSMUST00000165535.2
Gm17271
predicted gene, 17271
chr6_-_42693030 0.374 ENSMUST00000045140.4
Fam115a
family with sequence similarity 115, member A
chr11_-_64436653 0.374 ENSMUST00000177999.1
F930015N05Rik
RIKEN cDNA F930015N05 gene
chr15_-_81104999 0.359 ENSMUST00000109579.2
Mkl1
MKL (megakaryoblastic leukemia)/myocardin-like 1
chr17_-_29007925 0.356 ENSMUST00000009138.5
ENSMUST00000119274.1
Stk38

serine/threonine kinase 38

chr9_+_107888129 0.340 ENSMUST00000035202.2
Mon1a
MON1 homolog A (yeast)
chr7_+_83631959 0.312 ENSMUST00000075418.7
ENSMUST00000117410.1
Stard5

StAR-related lipid transfer (START) domain containing 5

chr10_+_121365078 0.284 ENSMUST00000040344.6
Gns
glucosamine (N-acetyl)-6-sulfatase
chr4_-_129378116 0.275 ENSMUST00000030610.2
Zbtb8a
zinc finger and BTB domain containing 8a
chrM_+_7759 0.266 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr5_+_121795034 0.251 ENSMUST00000162327.1
Atxn2
ataxin 2
chr7_-_55962466 0.238 ENSMUST00000032635.7
ENSMUST00000152649.1
Nipa2

non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human)

chr5_+_89028035 0.226 ENSMUST00000113216.2
ENSMUST00000134303.1
Slc4a4

solute carrier family 4 (anion exchanger), member 4

chr5_+_145084100 0.211 ENSMUST00000124379.1
Arpc1a
actin related protein 2/3 complex, subunit 1A
chr13_+_40859768 0.210 ENSMUST00000110191.2
Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr9_+_101074727 0.201 ENSMUST00000085177.3
Msl2
male-specific lethal 2 homolog (Drosophila)
chr4_+_59003121 0.199 ENSMUST00000095070.3
ENSMUST00000174664.1
Dnajc25
Gm20503
DnaJ (Hsp40) homolog, subfamily C, member 25
predicted gene 20503
chr2_-_36136773 0.194 ENSMUST00000028251.3
Rbm18
RNA binding motif protein 18
chr5_+_64812336 0.192 ENSMUST00000166409.1
Klf3
Kruppel-like factor 3 (basic)
chr2_-_36136602 0.191 ENSMUST00000122456.1
Rbm18
RNA binding motif protein 18
chrX_-_37104523 0.171 ENSMUST00000130324.1
Upf3b
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr3_+_67430096 0.161 ENSMUST00000077271.6
ENSMUST00000161009.1
Gfm1

G elongation factor, mitochondrial 1

chr2_-_156111954 0.154 ENSMUST00000142960.2
ENSMUST00000136296.2
ENSMUST00000059647.5
ENSMUST00000109604.2
ENSMUST00000138068.1
ENSMUST00000128499.1
Cpne1

Rbm12



copine I

RNA binding motif protein 12



chr19_+_8837676 0.152 ENSMUST00000159634.1
Bscl2
Bernardinelli-Seip congenital lipodystrophy 2 homolog (human)
chr7_-_73541738 0.144 ENSMUST00000169922.2
Chd2
chromodomain helicase DNA binding protein 2
chr13_-_113618549 0.141 ENSMUST00000109241.3
Snx18
sorting nexin 18
chr6_-_12109583 0.127 ENSMUST00000080891.5
Gm6578
predicted gene 6578
chr6_-_136173492 0.120 ENSMUST00000111905.1
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr1_+_82233112 0.119 ENSMUST00000023262.5
Gm9747
predicted gene 9747
chr12_+_8921598 0.118 ENSMUST00000020909.3
Laptm4a
lysosomal-associated protein transmembrane 4A
chr10_+_119992916 0.112 ENSMUST00000105261.2
Grip1
glutamate receptor interacting protein 1
chr5_-_148552783 0.111 ENSMUST00000079324.7
ENSMUST00000164904.1
Ubl3

ubiquitin-like 3

chrX_+_166344692 0.110 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
Gpm6b





glycoprotein m6b





chr2_-_127247768 0.109 ENSMUST00000003759.4
Ciao1
cytosolic iron-sulfur protein assembly 1
chr4_-_149774238 0.104 ENSMUST00000105686.2
Slc25a33
solute carrier family 25, member 33
chr2_-_127247620 0.100 ENSMUST00000174030.1
ENSMUST00000174863.1
Ciao1

cytosolic iron-sulfur protein assembly 1

chr16_-_38341812 0.092 ENSMUST00000114740.2
ENSMUST00000023501.8
Maats1

MYCBP-associated, testis expressed 1

chr12_-_54862783 0.090 ENSMUST00000078124.7
Cfl2
cofilin 2, muscle
chr8_-_83442648 0.085 ENSMUST00000167525.1
Scoc
short coiled-coil protein
chr11_-_69369377 0.082 ENSMUST00000092971.6
ENSMUST00000108661.1
Chd3

chromodomain helicase DNA binding protein 3

chr2_-_119662756 0.072 ENSMUST00000028768.1
ENSMUST00000110801.1
ENSMUST00000110802.1
Ndufaf1


NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1


chr3_+_95499273 0.069 ENSMUST00000015664.3
Ctsk
cathepsin K
chr10_-_76110956 0.038 ENSMUST00000120757.1
Slc5a4b
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr5_+_145083830 0.030 ENSMUST00000031625.8
Arpc1a
actin related protein 2/3 complex, subunit 1A
chr3_+_60877002 0.010 ENSMUST00000099086.2
Gm8325
predicted pseudogene 8325
chr9_+_52047150 0.009 ENSMUST00000163153.1
Rdx
radixin
chr14_-_121698417 0.004 ENSMUST00000040700.7
Dock9
dedicator of cytokinesis 9

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.4 1.2 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.2 0.9 GO:0010040 response to iron(II) ion(GO:0010040) positive regulation of hydrogen peroxide metabolic process(GO:0010726) negative regulation of synaptic transmission, dopaminergic(GO:0032227) negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963) regulation of peroxidase activity(GO:2000468)
0.2 0.6 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.2 0.6 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) negative regulation of interleukin-10 secretion(GO:2001180)
0.2 0.9 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2 0.6 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 0.4 GO:2000409 positive regulation of T cell extravasation(GO:2000409)
0.1 0.5 GO:1904800 regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800)
0.1 0.4 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 2.1 GO:0010842 retina layer formation(GO:0010842)
0.1 0.6 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.9 GO:0061339 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.1 0.6 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.8 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.2 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.2 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.4 GO:0033572 transferrin transport(GO:0033572)
0.0 0.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.6 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0 0.1 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.1 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0 0.1 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.3 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0 0.1 GO:0036089 cleavage furrow formation(GO:0036089)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.3 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.2 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.2 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.2 GO:0043984 histone H4-K16 acetylation(GO:0043984)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0099569 presynaptic cytoskeleton(GO:0099569)
0.2 0.9 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 1.2 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 0.9 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0097361 CIA complex(GO:0097361)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.2 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.5 GO:0044292 dendrite terminus(GO:0044292)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.6 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.4 GO:0016592 mediator complex(GO:0016592)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 0.6 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.1 1.5 GO:0005522 profilin binding(GO:0005522)
0.1 0.9 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 0.3 GO:0032052 bile acid binding(GO:0032052)
0.1 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 1.2 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.6 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.6 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.6 GO:0042165 neurotransmitter binding(GO:0042165)
0.0 0.3 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.6 GO:0070888 E-box binding(GO:0070888)
0.0 0.8 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.4 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.4 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.9 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.8 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 1.2 PID_TELOMERASE_PATHWAY Regulation of Telomerase

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 0.6 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.9 REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.3 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.6 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.3 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.0 0.9 REACTOME_AMYLOIDS Genes involved in Amyloids