Motif ID: Pou5f1

Z-value: 1.339


Transcription factors associated with Pou5f1:

Gene SymbolEntrez IDGene Name
Pou5f1 ENSMUSG00000024406.10 Pou5f1



Activity profile for motif Pou5f1.

activity profile for motif Pou5f1


Sorted Z-values histogram for motif Pou5f1

Sorted Z-values for motif Pou5f1



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou5f1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_66831625 11.086 ENSMUST00000164163.1
Sla
src-like adaptor
chr8_-_84773381 10.685 ENSMUST00000109764.1
Nfix
nuclear factor I/X
chr8_+_54954728 8.778 ENSMUST00000033915.7
Gpm6a
glycoprotein m6a
chr4_+_97772734 8.297 ENSMUST00000152023.1
Nfia
nuclear factor I/A
chr14_-_79771305 8.194 ENSMUST00000039568.5
Pcdh8
protocadherin 8
chr6_+_136518820 8.114 ENSMUST00000032335.6
Atf7ip
activating transcription factor 7 interacting protein
chr5_+_129584169 6.750 ENSMUST00000031390.8
Mmp17
matrix metallopeptidase 17
chr7_+_91090697 6.738 ENSMUST00000107196.2
Dlg2
discs, large homolog 2 (Drosophila)
chr7_+_91090728 6.611 ENSMUST00000074273.3
Dlg2
discs, large homolog 2 (Drosophila)
chr11_-_69605829 6.457 ENSMUST00000047889.6
Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr15_-_100599864 6.314 ENSMUST00000177247.2
ENSMUST00000177505.2
Pou6f1

POU domain, class 6, transcription factor 1

chr3_-_80802789 6.295 ENSMUST00000107745.1
ENSMUST00000075316.4
Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr5_+_66968559 6.237 ENSMUST00000127184.1
Limch1
LIM and calponin homology domains 1
chr5_+_66968961 6.191 ENSMUST00000132991.1
Limch1
LIM and calponin homology domains 1
chr14_-_102982630 5.812 ENSMUST00000184744.1
KCTD12
mmu-mir-5130
chr14_-_88471396 5.717 ENSMUST00000061628.5
Pcdh20
protocadherin 20
chr12_+_29528382 5.483 ENSMUST00000049784.9
Myt1l
myelin transcription factor 1-like
chr8_+_118283719 5.059 ENSMUST00000117160.1
Cdh13
cadherin 13
chr7_-_78578308 4.974 ENSMUST00000039431.7
Ntrk3
neurotrophic tyrosine kinase, receptor, type 3
chr5_+_64812336 4.892 ENSMUST00000166409.1
Klf3
Kruppel-like factor 3 (basic)
chr11_+_57011945 4.869 ENSMUST00000094179.4
Gria1
glutamate receptor, ionotropic, AMPA1 (alpha 1)
chr11_+_57011798 4.847 ENSMUST00000036315.9
Gria1
glutamate receptor, ionotropic, AMPA1 (alpha 1)
chrX_-_103483205 4.797 ENSMUST00000127786.2
Xist
inactive X specific transcripts
chr4_-_82705735 4.742 ENSMUST00000155821.1
Nfib
nuclear factor I/B
chr11_+_98741871 4.723 ENSMUST00000103139.4
Thra
thyroid hormone receptor alpha
chr2_+_124610573 4.700 ENSMUST00000103239.3
ENSMUST00000103240.2
Sema6d

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D

chr13_+_42680565 4.447 ENSMUST00000128646.1
Phactr1
phosphatase and actin regulator 1
chr13_+_97241096 4.361 ENSMUST00000041623.7
Enc1
ectodermal-neural cortex 1
chr5_+_66968416 4.304 ENSMUST00000038188.7
Limch1
LIM and calponin homology domains 1
chr1_-_154725920 4.247 ENSMUST00000004214.8
Cacna1e
calcium channel, voltage-dependent, R type, alpha 1E subunit
chr6_-_13839916 4.245 ENSMUST00000060442.7
Gpr85
G protein-coupled receptor 85
chr10_+_85386813 4.245 ENSMUST00000105307.1
ENSMUST00000020231.3
Btbd11

BTB (POZ) domain containing 11

chr11_+_110399115 4.233 ENSMUST00000020949.5
ENSMUST00000100260.1
Map2k6

mitogen-activated protein kinase kinase 6

chr2_-_66440753 4.196 ENSMUST00000112371.2
ENSMUST00000138910.1
Scn1a

sodium channel, voltage-gated, type I, alpha

chr10_-_127620960 4.160 ENSMUST00000121829.1
Lrp1
low density lipoprotein receptor-related protein 1
chr6_+_108213086 4.110 ENSMUST00000032192.6
Itpr1
inositol 1,4,5-trisphosphate receptor 1
chr18_-_42899470 4.075 ENSMUST00000120632.1
Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr11_+_98741805 4.060 ENSMUST00000064187.5
Thra
thyroid hormone receptor alpha
chr10_+_118860826 3.994 ENSMUST00000059966.4
4932442E05Rik
RIKEN cDNA 4932442E05 gene
chrX_-_95444789 3.966 ENSMUST00000084535.5
Amer1
APC membrane recruitment 1
chr6_+_92092369 3.935 ENSMUST00000113463.1
Nr2c2
nuclear receptor subfamily 2, group C, member 2
chr18_-_42899294 3.932 ENSMUST00000117687.1
Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr5_+_76840597 3.920 ENSMUST00000120639.2
ENSMUST00000163347.1
ENSMUST00000121851.1
C530008M17Rik


RIKEN cDNA C530008M17 gene


chr7_+_82174796 3.898 ENSMUST00000032874.7
Sh3gl3
SH3-domain GRB2-like 3
chr11_-_98053415 3.855 ENSMUST00000017544.2
Stac2
SH3 and cysteine rich domain 2
chr18_-_43393346 3.843 ENSMUST00000025379.7
Dpysl3
dihydropyrimidinase-like 3
chr11_-_116024489 3.834 ENSMUST00000016703.7
H3f3b
H3 histone, family 3B
chr1_+_177444653 3.833 ENSMUST00000094276.3
Zbtb18
zinc finger and BTB domain containing 18
chr1_-_168431502 3.766 ENSMUST00000064438.4
Pbx1
pre B cell leukemia homeobox 1
chr4_+_144893077 3.762 ENSMUST00000154208.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr15_-_100599983 3.677 ENSMUST00000073837.6
Pou6f1
POU domain, class 6, transcription factor 1
chr4_-_64046925 3.668 ENSMUST00000107377.3
Tnc
tenascin C
chr3_+_13946368 3.644 ENSMUST00000171075.1
ENSMUST00000108372.2
Ralyl

RALY RNA binding protein-like

chr10_-_127620922 3.606 ENSMUST00000118455.1
Lrp1
low density lipoprotein receptor-related protein 1
chr7_+_87803815 3.593 ENSMUST00000125009.1
ENSMUST00000155358.1
Grm5

glutamate receptor, metabotropic 5

chr1_-_168431695 3.573 ENSMUST00000176790.1
Pbx1
pre B cell leukemia homeobox 1
chr7_+_82175156 3.521 ENSMUST00000180243.1
Sh3gl3
SH3-domain GRB2-like 3
chr18_+_37484955 3.495 ENSMUST00000053856.4
Pcdhb17
protocadherin beta 17
chr3_-_84220853 3.411 ENSMUST00000154152.1
ENSMUST00000107693.2
ENSMUST00000107695.2
Trim2


tripartite motif-containing 2


chr16_+_23224724 3.356 ENSMUST00000023601.7
St6gal1
beta galactoside alpha 2,6 sialyltransferase 1
chr16_+_91729281 3.324 ENSMUST00000114001.1
ENSMUST00000113999.1
ENSMUST00000064797.5
ENSMUST00000114002.2
ENSMUST00000095909.3
ENSMUST00000056482.7
ENSMUST00000113996.1
Itsn1






intersectin 1 (SH3 domain protein 1A)






chr18_+_69593361 3.232 ENSMUST00000114978.2
ENSMUST00000114977.1
Tcf4

transcription factor 4

chr11_+_103103051 3.206 ENSMUST00000152971.1
Acbd4
acyl-Coenzyme A binding domain containing 4
chr10_+_106470281 3.204 ENSMUST00000029404.9
ENSMUST00000169303.1
Ppfia2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr4_+_144893127 3.174 ENSMUST00000142808.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr16_+_42907563 3.088 ENSMUST00000151244.1
ENSMUST00000114694.2
Zbtb20

zinc finger and BTB domain containing 20

chr1_+_34579693 3.036 ENSMUST00000052670.8
Amer3
APC membrane recruitment 3
chr6_-_138421379 3.000 ENSMUST00000163065.1
Lmo3
LIM domain only 3
chr2_-_33087169 2.923 ENSMUST00000102810.3
Garnl3
GTPase activating RANGAP domain-like 3
chr6_-_136171722 2.904 ENSMUST00000053880.6
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr5_+_105732063 2.889 ENSMUST00000154807.1
Lrrc8d
leucine rich repeat containing 8D
chr15_+_57694651 2.879 ENSMUST00000096430.4
Zhx2
zinc fingers and homeoboxes 2
chr2_-_6721890 2.819 ENSMUST00000114927.2
Celf2
CUGBP, Elav-like family member 2
chr4_+_123183722 2.816 ENSMUST00000152194.1
Hpcal4
hippocalcin-like 4
chr1_-_165934900 2.815 ENSMUST00000069609.5
ENSMUST00000111427.2
ENSMUST00000111426.4
Pou2f1


POU domain, class 2, transcription factor 1


chr5_+_105731755 2.758 ENSMUST00000127686.1
Lrrc8d
leucine rich repeat containing 8D
chr1_+_91540553 2.755 ENSMUST00000027538.7
Asb1
ankyrin repeat and SOCS box-containing 1
chr11_+_58954675 2.742 ENSMUST00000047697.5
ENSMUST00000108817.3
Trim17
Hist3h2a
tripartite motif-containing 17
histone cluster 3, H2a
chr2_-_66410064 2.721 ENSMUST00000112366.1
Scn1a
sodium channel, voltage-gated, type I, alpha
chrX_+_93675088 2.718 ENSMUST00000045898.3
Pcyt1b
phosphate cytidylyltransferase 1, choline, beta isoform
chr11_-_30198232 2.709 ENSMUST00000102838.3
Sptbn1
spectrin beta, non-erythrocytic 1
chr2_-_6722187 2.661 ENSMUST00000182657.1
Celf2
CUGBP, Elav-like family member 2
chr5_-_142895233 2.625 ENSMUST00000035985.7
Fbxl18
F-box and leucine-rich repeat protein 18
chr1_-_64121389 2.608 ENSMUST00000055001.3
Klf7
Kruppel-like factor 7 (ubiquitous)
chr17_-_90455872 2.554 ENSMUST00000174337.1
ENSMUST00000172466.1
Nrxn1

neurexin I

chr17_-_35164891 2.544 ENSMUST00000025253.5
Prrc2a
proline-rich coiled-coil 2A
chr18_+_69346143 2.499 ENSMUST00000114980.1
Tcf4
transcription factor 4
chr10_+_39612934 2.467 ENSMUST00000019987.6
Traf3ip2
TRAF3 interacting protein 2
chr6_-_55681257 2.398 ENSMUST00000044767.8
Neurod6
neurogenic differentiation 6
chr10_+_18469958 2.392 ENSMUST00000162891.1
ENSMUST00000100054.3
Nhsl1

NHS-like 1

chr18_-_79109391 2.389 ENSMUST00000025430.8
ENSMUST00000161465.2
Setbp1

SET binding protein 1

chrX_+_94234594 2.366 ENSMUST00000153900.1
Klhl15
kelch-like 15
chr18_+_65582239 2.352 ENSMUST00000182684.1
Zfp532
zinc finger protein 532
chr19_+_26750939 2.351 ENSMUST00000175953.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr4_+_102254993 2.347 ENSMUST00000106908.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr2_+_55437100 2.334 ENSMUST00000112633.2
ENSMUST00000112632.1
Kcnj3

potassium inwardly-rectifying channel, subfamily J, member 3

chr9_+_21936986 2.309 ENSMUST00000046371.6
BC018242
cDNA sequence BC018242
chr14_-_39472825 2.302 ENSMUST00000168810.2
ENSMUST00000173780.1
ENSMUST00000166968.2
Nrg3


neuregulin 3


chrX_-_165327376 2.264 ENSMUST00000058787.8
Glra2
glycine receptor, alpha 2 subunit
chr15_+_18818895 2.248 ENSMUST00000166873.2
Cdh10
cadherin 10
chr16_-_91728701 2.208 ENSMUST00000114023.2
ENSMUST00000117644.1
Cryzl1

crystallin, zeta (quinone reductase)-like 1

chr2_+_155382186 2.200 ENSMUST00000134218.1
Trp53inp2
transformation related protein 53 inducible nuclear protein 2
chr14_-_124677089 2.174 ENSMUST00000095529.3
Fgf14
fibroblast growth factor 14
chr14_+_17660956 2.163 ENSMUST00000022303.7
ENSMUST00000091471.4
Thrb

thyroid hormone receptor beta

chr1_-_25228814 2.135 ENSMUST00000126626.1
Bai3
brain-specific angiogenesis inhibitor 3
chr11_-_98775333 2.116 ENSMUST00000064941.6
Nr1d1
nuclear receptor subfamily 1, group D, member 1
chr9_+_86485407 2.112 ENSMUST00000034987.8
Dopey1
dopey family member 1
chr1_+_66386968 2.111 ENSMUST00000145419.1
Map2
microtubule-associated protein 2
chr1_-_91459254 2.050 ENSMUST00000069620.8
Per2
period circadian clock 2
chr12_-_34528844 2.043 ENSMUST00000110819.2
Hdac9
histone deacetylase 9
chr13_-_41358990 2.008 ENSMUST00000163623.1
Nedd9
neural precursor cell expressed, developmentally down-regulated gene 9
chr13_+_16014457 2.000 ENSMUST00000164993.1
Inhba
inhibin beta-A
chr18_-_37969742 1.968 ENSMUST00000166148.1
ENSMUST00000163131.1
ENSMUST00000043437.7
Fchsd1


FCH and double SH3 domains 1


chr1_-_168432270 1.956 ENSMUST00000072863.4
Pbx1
pre B cell leukemia homeobox 1
chr14_+_70890099 1.956 ENSMUST00000022699.8
Gfra2
glial cell line derived neurotrophic factor family receptor alpha 2
chr1_-_126830632 1.952 ENSMUST00000112583.1
ENSMUST00000094609.3
Nckap5

NCK-associated protein 5

chr2_-_45117349 1.922 ENSMUST00000176438.2
Zeb2
zinc finger E-box binding homeobox 2
chr12_+_71048338 1.900 ENSMUST00000135709.1
Arid4a
AT rich interactive domain 4A (RBP1-like)
chr6_+_88724667 1.896 ENSMUST00000163271.1
Mgll
monoglyceride lipase
chr13_+_40917626 1.878 ENSMUST00000067778.6
Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr10_-_127621107 1.877 ENSMUST00000049149.8
Lrp1
low density lipoprotein receptor-related protein 1
chrX_+_166344692 1.852 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
Gpm6b





glycoprotein m6b





chr2_-_59948155 1.837 ENSMUST00000153136.1
Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr12_-_86988676 1.823 ENSMUST00000095521.2
Zdhhc22
zinc finger, DHHC-type containing 22
chr10_-_64090265 1.806 ENSMUST00000105439.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr18_+_69345721 1.772 ENSMUST00000078486.6
ENSMUST00000114982.1
Tcf4

transcription factor 4

chr8_+_120488416 1.766 ENSMUST00000034279.9
Gse1
genetic suppressor element 1
chr1_-_168431896 1.755 ENSMUST00000176540.1
Pbx1
pre B cell leukemia homeobox 1
chr13_-_54688264 1.753 ENSMUST00000150626.1
ENSMUST00000134177.1
Rnf44

ring finger protein 44

chr5_+_111417263 1.733 ENSMUST00000094463.4
Mn1
meningioma 1
chr10_-_64090241 1.706 ENSMUST00000133588.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr2_-_77703252 1.702 ENSMUST00000171063.1
Zfp385b
zinc finger protein 385B
chr8_+_70754679 1.688 ENSMUST00000110093.2
ENSMUST00000143118.1
ENSMUST00000034301.5
ENSMUST00000110090.1
Rab3a



RAB3A, member RAS oncogene family



chr19_+_8941865 1.679 ENSMUST00000096240.2
Mta2
metastasis-associated gene family, member 2
chr2_-_161109017 1.664 ENSMUST00000039782.7
ENSMUST00000134178.1
Chd6

chromodomain helicase DNA binding protein 6

chr13_+_23934434 1.640 ENSMUST00000072391.1
Hist1h2aa
histone cluster 1, H2aa
chr6_-_56901870 1.639 ENSMUST00000101367.2
Nt5c3
5'-nucleotidase, cytosolic III
chr16_-_17144415 1.627 ENSMUST00000115709.1
Ccdc116
coiled-coil domain containing 116
chr8_+_70234613 1.620 ENSMUST00000145078.1
Sugp2
SURP and G patch domain containing 2
chr3_-_58885212 1.608 ENSMUST00000055636.6
ENSMUST00000072551.6
ENSMUST00000051408.7
Clrn1


clarin 1


chr13_-_28953690 1.593 ENSMUST00000067230.5
Sox4
SRY-box containing gene 4
chr13_+_40886758 1.569 ENSMUST00000069958.7
Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr7_-_37769624 1.562 ENSMUST00000175941.1
Zfp536
zinc finger protein 536
chr1_-_126830786 1.562 ENSMUST00000162646.1
Nckap5
NCK-associated protein 5
chr8_-_33747724 1.542 ENSMUST00000179364.1
Smim18
small integral membrane protein 18
chr11_-_84068766 1.542 ENSMUST00000018792.5
Dusp14
dual specificity phosphatase 14
chr1_-_66817536 1.522 ENSMUST00000068168.3
ENSMUST00000113987.1
Kansl1l

KAT8 regulatory NSL complex subunit 1-like

chr5_+_13399309 1.515 ENSMUST00000030714.7
ENSMUST00000141968.1
Sema3a

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A

chr14_+_45219993 1.507 ENSMUST00000146150.1
Gpr137c
G protein-coupled receptor 137C
chr16_-_4880284 1.488 ENSMUST00000037843.6
Ubald1
UBA-like domain containing 1
chr16_-_91728599 1.479 ENSMUST00000122254.1
Cryzl1
crystallin, zeta (quinone reductase)-like 1
chr8_-_70234401 1.479 ENSMUST00000019679.5
Armc6
armadillo repeat containing 6
chr9_-_102354685 1.463 ENSMUST00000035129.7
ENSMUST00000085169.5
Ephb1

Eph receptor B1

chr7_-_28372597 1.460 ENSMUST00000144700.1
Plekhg2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr16_-_91728975 1.457 ENSMUST00000073466.6
Cryzl1
crystallin, zeta (quinone reductase)-like 1
chr13_-_54688246 1.430 ENSMUST00000122935.1
ENSMUST00000128257.1
Rnf44

ring finger protein 44

chr2_-_18048784 1.426 ENSMUST00000142856.1
Skida1
SKI/DACH domain containing 1
chr5_-_122989086 1.425 ENSMUST00000046073.9
Kdm2b
lysine (K)-specific demethylase 2B
chr7_+_126776939 1.423 ENSMUST00000038614.5
ENSMUST00000170882.1
ENSMUST00000106359.1
ENSMUST00000106357.1
ENSMUST00000145762.1
ENSMUST00000132643.1
ENSMUST00000106356.1
Ypel3






yippee-like 3 (Drosophila)






chr4_-_62360524 1.422 ENSMUST00000107461.1
ENSMUST00000084528.3
Fkbp15

FK506 binding protein 15

chr9_-_71896047 1.397 ENSMUST00000184448.1
Tcf12
transcription factor 12
chr18_+_65582281 1.381 ENSMUST00000183319.1
Zfp532
zinc finger protein 532
chr2_-_180273488 1.381 ENSMUST00000108891.1
Cables2
CDK5 and Abl enzyme substrate 2
chr5_+_123015010 1.377 ENSMUST00000121652.1
ENSMUST00000051016.4
Orai1

ORAI calcium release-activated calcium modulator 1

chr16_+_17144600 1.369 ENSMUST00000115702.1
Ydjc
YdjC homolog (bacterial)
chr8_-_70234097 1.367 ENSMUST00000130319.1
Armc6
armadillo repeat containing 6
chr10_-_79908891 1.361 ENSMUST00000165684.1
ENSMUST00000164705.1
ENSMUST00000105378.2
ENSMUST00000170409.1
Med16



mediator complex subunit 16



chr4_+_152039315 1.360 ENSMUST00000084116.6
ENSMUST00000105663.1
ENSMUST00000103197.3
Nol9


nucleolar protein 9


chr3_-_61365951 1.348 ENSMUST00000066298.2
B430305J03Rik
RIKEN cDNA B430305J03 gene
chr19_-_37176055 1.346 ENSMUST00000142973.1
ENSMUST00000154376.1
Cpeb3

cytoplasmic polyadenylation element binding protein 3

chr3_-_144202300 1.324 ENSMUST00000121796.1
ENSMUST00000121112.1
Lmo4

LIM domain only 4

chr18_+_65582390 1.324 ENSMUST00000169679.1
ENSMUST00000183326.1
Zfp532

zinc finger protein 532

chr9_+_14276301 1.319 ENSMUST00000034507.7
Sesn3
sestrin 3
chr5_-_122988533 1.310 ENSMUST00000086200.4
ENSMUST00000156474.1
Kdm2b

lysine (K)-specific demethylase 2B

chr9_+_59578192 1.309 ENSMUST00000118549.1
ENSMUST00000034840.3
Celf6

CUGBP, Elav-like family member 6

chr10_-_115362191 1.308 ENSMUST00000092170.5
Tmem19
transmembrane protein 19
chr18_+_69344503 1.291 ENSMUST00000114985.3
Tcf4
transcription factor 4
chr12_-_79192248 1.268 ENSMUST00000161204.1
Rdh11
retinol dehydrogenase 11
chr14_+_13453937 1.255 ENSMUST00000153954.1
Synpr
synaptoporin
chr16_-_23225334 1.237 ENSMUST00000055369.4
BC106179
cDNA sequence BC106179
chr6_-_30304513 1.234 ENSMUST00000094543.2
ENSMUST00000102993.3
Ube2h

ubiquitin-conjugating enzyme E2H

chr2_+_155381808 1.219 ENSMUST00000043237.7
ENSMUST00000174685.1
Trp53inp2

transformation related protein 53 inducible nuclear protein 2

chr1_-_64121456 1.193 ENSMUST00000142009.1
ENSMUST00000114086.1
Klf7

Kruppel-like factor 7 (ubiquitous)

chr17_-_46556158 1.165 ENSMUST00000015749.5
Srf
serum response factor
chr8_+_31150307 1.152 ENSMUST00000098842.2
Tti2
TELO2 interacting protein 2
chr7_+_107370728 1.131 ENSMUST00000137663.1
ENSMUST00000073459.5
Syt9

synaptotagmin IX

chr16_-_22439570 1.127 ENSMUST00000170393.1
Etv5
ets variant gene 5
chr9_-_107710475 1.118 ENSMUST00000080560.3
Sema3f
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr17_-_35909626 1.114 ENSMUST00000141132.1
Atat1
alpha tubulin acetyltransferase 1
chr11_-_84069179 1.090 ENSMUST00000138208.1
Dusp14
dual specificity phosphatase 14
chr11_+_74830920 1.089 ENSMUST00000000291.2
Mnt
max binding protein
chr12_+_52699297 1.080 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chr2_-_120539852 1.077 ENSMUST00000171215.1
Zfp106
zinc finger protein 106
chr18_-_80151467 1.076 ENSMUST00000066743.9
Adnp2
ADNP homeobox 2
chr3_-_95015416 1.055 ENSMUST00000132195.1
Zfp687
zinc finger protein 687
chr15_+_82147238 1.048 ENSMUST00000023100.6
Srebf2
sterol regulatory element binding factor 2
chr11_-_100527862 1.043 ENSMUST00000107385.1
Acly
ATP citrate lyase
chr18_+_52767994 1.035 ENSMUST00000025413.7
ENSMUST00000163742.2
ENSMUST00000178011.1
Sncaip


synuclein, alpha interacting protein (synphilin)


chr19_-_6921804 1.018 ENSMUST00000025906.4
Esrra
estrogen related receptor, alpha
chr1_+_140246216 1.000 ENSMUST00000119786.1
ENSMUST00000120796.1
ENSMUST00000060201.8
ENSMUST00000120709.1
Kcnt2



potassium channel, subfamily T, member 2




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.8 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
2.4 9.6 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
1.7 5.0 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
1.6 6.5 GO:1903288 positive regulation of potassium ion import(GO:1903288)
1.6 4.8 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
1.2 3.6 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
1.2 4.7 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
1.1 4.4 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
1.0 3.8 GO:1902340 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
1.0 13.3 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.9 3.7 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.8 4.2 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.8 1.7 GO:0050975 sensory perception of touch(GO:0050975)
0.8 3.4 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
0.8 3.4 GO:2000110 protein sialylation(GO:1990743) negative regulation of macrophage apoptotic process(GO:2000110)
0.8 11.5 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.8 8.8 GO:0042118 endothelial cell activation(GO:0042118)
0.8 6.9 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.8 2.3 GO:0060596 mammary placode formation(GO:0060596)
0.7 2.9 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.7 2.2 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.7 4.2 GO:0032308 positive regulation of prostaglandin secretion(GO:0032308)
0.7 2.1 GO:0010871 negative regulation of receptor biosynthetic process(GO:0010871)
0.7 4.1 GO:0042045 epithelial fluid transport(GO:0042045)
0.7 2.0 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
0.7 8.7 GO:0072189 ureter development(GO:0072189)
0.7 4.0 GO:2001012 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.6 5.8 GO:0042756 drinking behavior(GO:0042756)
0.6 1.9 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.6 8.0 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.6 3.1 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.6 9.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.6 8.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.6 3.4 GO:0036438 maintenance of lens transparency(GO:0036438)
0.6 7.4 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.6 1.7 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.5 2.7 GO:0021993 initiation of neural tube closure(GO:0021993)
0.5 1.6 GO:0003289 atrial septum primum morphogenesis(GO:0003289)
0.5 1.4 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.4 2.6 GO:0097491 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.4 2.2 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.4 1.3 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.4 2.0 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) regulation of follicle-stimulating hormone secretion(GO:0046880) follicle-stimulating hormone secretion(GO:0046884) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.4 2.4 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.4 1.2 GO:1901228 positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.4 2.7 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.4 2.7 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.4 2.3 GO:0060012 synaptic transmission, glycinergic(GO:0060012) cellular response to zinc ion(GO:0071294)
0.4 13.0 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.4 1.1 GO:0071929 alpha-tubulin acetylation(GO:0071929) positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.4 1.9 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.3 2.3 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.3 1.6 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.3 16.0 GO:0001919 regulation of receptor recycling(GO:0001919)
0.3 2.0 GO:0033139 regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033139)
0.3 1.9 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.3 1.5 GO:2001015 skeletal muscle satellite cell activation(GO:0014719) negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.3 1.8 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.3 0.9 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.3 1.4 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.3 0.6 GO:0061324 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023) positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of centromeric sister chromatid cohesion(GO:0070602) regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901963)
0.3 8.9 GO:0030325 adrenal gland development(GO:0030325)
0.3 1.1 GO:2000481 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
0.3 2.4 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.3 2.4 GO:0097475 motor neuron migration(GO:0097475)
0.3 1.0 GO:0010886 positive regulation of cholesterol storage(GO:0010886) negative regulation of cholesterol efflux(GO:0090370)
0.3 2.4 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.2 3.5 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.2 3.9 GO:0048520 positive regulation of behavior(GO:0048520)
0.2 2.7 GO:0070914 UV-damage excision repair(GO:0070914)
0.2 1.1 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.2 1.6 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.2 0.9 GO:0023041 neuronal signal transduction(GO:0023041)
0.2 16.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2 2.3 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841)
0.2 11.4 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.2 2.1 GO:0006895 Golgi to endosome transport(GO:0006895)
0.2 2.2 GO:0021542 dentate gyrus development(GO:0021542)
0.2 2.9 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.2 1.6 GO:0046085 adenosine metabolic process(GO:0046085)
0.2 4.7 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.1 0.4 GO:0070269 pyroptosis(GO:0070269)
0.1 1.3 GO:0038203 TORC2 signaling(GO:0038203)
0.1 1.6 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.1 0.7 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.1 5.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 0.8 GO:0051013 microtubule severing(GO:0051013)
0.1 0.5 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 0.4 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.1 0.6 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.7 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.1 20.7 GO:0031032 actomyosin structure organization(GO:0031032)
0.1 1.3 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.1 3.4 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 0.7 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.1 0.6 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 0.4 GO:0070166 enamel mineralization(GO:0070166)
0.1 0.7 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 2.0 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 4.2 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.1 1.4 GO:0002115 store-operated calcium entry(GO:0002115)
0.1 1.0 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.1 1.8 GO:0018345 protein palmitoylation(GO:0018345)
0.1 0.6 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.1 2.7 GO:0001541 ovarian follicle development(GO:0001541)
0.1 1.6 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.1 1.1 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.1 0.3 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.1 1.7 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.1 1.0 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.1 1.7 GO:0010762 regulation of fibroblast migration(GO:0010762)
0.0 3.1 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 0.6 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.2 GO:0008343 adult feeding behavior(GO:0008343)
0.0 5.2 GO:0098656 anion transmembrane transport(GO:0098656)
0.0 0.7 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.4 GO:0031111 negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.0 0.2 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 3.4 GO:0000045 autophagosome assembly(GO:0000045)
0.0 0.7 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.0 1.2 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.6 GO:0030953 astral microtubule organization(GO:0030953)
0.0 2.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 4.0 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.6 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.4 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.0 1.1 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.5 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 1.4 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 3.8 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.3 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 0.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.6 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 2.8 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 0.2 GO:0043388 positive regulation of DNA binding(GO:0043388)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.5 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 2.3 GO:0006402 mRNA catabolic process(GO:0006402)
0.0 0.5 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.7 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.3 GO:0019835 cytolysis(GO:0019835)
0.0 1.0 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.1 GO:1900194 receptor guanylyl cyclase signaling pathway(GO:0007168) negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.0 0.1 GO:0048752 semicircular canal morphogenesis(GO:0048752)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 9.7 GO:0044308 axonal spine(GO:0044308)
1.4 4.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.9 6.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.8 12.8 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.7 13.9 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.7 2.0 GO:0043512 inhibin A complex(GO:0043512)
0.5 2.7 GO:0032437 cuticular plate(GO:0032437)
0.5 1.6 GO:1903095 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.5 4.8 GO:0000805 X chromosome(GO:0000805)
0.5 6.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.4 3.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.4 4.7 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.4 8.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.3 3.4 GO:0000138 Golgi trans cisterna(GO:0000138)
0.2 2.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.2 3.7 GO:0005614 interstitial matrix(GO:0005614)
0.2 6.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 9.6 GO:0044295 axonal growth cone(GO:0044295)
0.2 6.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 14.1 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 1.7 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 2.0 GO:0043196 varicosity(GO:0043196)
0.1 0.7 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 1.0 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 2.4 GO:0071564 npBAF complex(GO:0071564)
0.1 0.6 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 0.4 GO:0061702 inflammasome complex(GO:0061702)
0.1 0.7 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 1.3 GO:0061700 GATOR2 complex(GO:0061700)
0.1 1.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 1.5 GO:0032433 filopodium tip(GO:0032433)
0.1 1.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.3 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.1 6.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 11.6 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.4 GO:0044316 cone cell pedicle(GO:0044316)
0.1 1.7 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 1.1 GO:0031045 dense core granule(GO:0031045)
0.1 1.6 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 1.7 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 3.8 GO:0045171 intercellular bridge(GO:0045171)
0.1 3.6 GO:0031941 filamentous actin(GO:0031941)
0.1 1.1 GO:0034704 calcium channel complex(GO:0034704)
0.1 7.4 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 2.3 GO:0034707 chloride channel complex(GO:0034707)
0.1 11.0 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 1.9 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 6.4 GO:0034702 ion channel complex(GO:0034702)
0.0 0.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 3.4 GO:0005776 autophagosome(GO:0005776)
0.0 2.0 GO:0031594 neuromuscular junction(GO:0031594)
0.0 6.3 GO:0005769 early endosome(GO:0005769)
0.0 2.0 GO:0005884 actin filament(GO:0005884)
0.0 8.9 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 1.7 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.8 GO:0043198 dendritic shaft(GO:0043198)
0.0 2.0 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 0.5 GO:0016580 Sin3 complex(GO:0016580)
0.0 3.8 GO:0043235 receptor complex(GO:0043235)
0.0 1.5 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 0.9 GO:0031519 PcG protein complex(GO:0031519)
0.0 2.6 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 2.0 GO:0000922 spindle pole(GO:0000922)
0.0 0.5 GO:0030315 T-tubule(GO:0030315)
0.0 0.6 GO:1990391 DNA repair complex(GO:1990391)
0.0 2.0 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.9 GO:0005814 centriole(GO:0005814)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 9.6 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
2.9 8.8 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
2.3 16.0 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
2.2 8.8 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
1.4 4.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
1.2 8.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
1.1 3.4 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
1.1 6.5 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
1.0 5.1 GO:0055100 adiponectin binding(GO:0055100)
1.0 5.0 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.8 3.4 GO:0097109 neuroligin family protein binding(GO:0097109)
0.8 2.3 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.7 2.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.7 3.4 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.7 2.0 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.6 6.5 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.6 3.7 GO:0045545 syndecan binding(GO:0045545)
0.6 13.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.5 2.7 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.5 7.9 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.5 2.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.4 5.6 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.4 3.8 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.4 6.9 GO:0031402 sodium ion binding(GO:0031402)
0.3 2.0 GO:0070699 type II activin receptor binding(GO:0070699)
0.3 6.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.3 1.6 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.3 4.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.3 11.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.3 2.1 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.2 3.4 GO:0045499 chemorepellent activity(GO:0045499)
0.2 1.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005) axon guidance receptor activity(GO:0008046)
0.2 3.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 0.7 GO:0016901 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.2 2.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 4.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.2 1.4 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.2 1.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.2 0.7 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.2 4.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.2 1.4 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.2 1.0 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.2 1.1 GO:0001515 opioid peptide activity(GO:0001515)
0.2 4.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 4.7 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 4.0 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1 2.7 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.8 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.6 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.7 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 0.4 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.1 8.6 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 1.9 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 9.7 GO:0005262 calcium channel activity(GO:0005262)
0.1 2.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 2.0 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 5.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 8.0 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 0.8 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 1.6 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 5.5 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 0.5 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.3 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.1 1.9 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.7 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 2.1 GO:0030506 ankyrin binding(GO:0030506)
0.1 7.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.6 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 5.1 GO:0017022 myosin binding(GO:0017022)
0.1 3.2 GO:0030552 cAMP binding(GO:0030552)
0.1 2.9 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 0.6 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.1 1.8 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.4 GO:0034979 NAD-dependent protein deacetylase activity(GO:0034979)
0.1 0.2 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.0 0.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:1990188 euchromatin binding(GO:1990188)
0.0 3.3 GO:0019209 kinase activator activity(GO:0019209)
0.0 1.7 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 13.8 GO:0003779 actin binding(GO:0003779)
0.0 0.3 GO:0030553 cGMP binding(GO:0030553) 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 1.2 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 3.9 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 2.1 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 2.2 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.3 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 9.3 GO:0016887 ATPase activity(GO:0016887)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.6 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 2.1 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 0.0 GO:0019002 GMP binding(GO:0019002)
0.0 5.1 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 4.7 GO:0008289 lipid binding(GO:0008289)
0.0 0.5 GO:0003707 steroid hormone receptor activity(GO:0003707)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 16.3 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.3 9.6 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.3 10.9 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.2 4.2 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.2 4.2 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.2 4.4 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.2 6.9 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.2 10.5 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.2 3.7 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.2 8.0 PID_ATR_PATHWAY ATR signaling pathway
0.2 2.3 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.1 6.3 PID_SHP2_PATHWAY SHP2 signaling
0.1 2.3 ST_ADRENERGIC Adrenergic Pathway
0.1 8.6 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.1 3.9 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.1 12.5 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.1 2.9 PID_REELIN_PATHWAY Reelin signaling pathway
0.1 1.0 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 0.5 PID_AVB3_INTEGRIN_PATHWAY Integrins in angiogenesis
0.1 7.3 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 4.1 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.1 2.0 PID_ALK1_PATHWAY ALK1 signaling events
0.1 0.5 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 1.8 PID_CD8_TCR_PATHWAY TCR signaling in naïve CD8+ T cells
0.1 2.7 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.1 2.4 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 0.7 PID_TCPTP_PATHWAY Signaling events mediated by TCPTP
0.0 2.1 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.9 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 4.2 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.1 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 0.5 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 18.9 REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.5 2.0 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.5 6.8 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.4 14.9 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.3 3.4 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.3 2.8 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.2 1.4 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.2 6.6 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.2 4.2 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.2 4.7 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.2 6.1 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.2 1.6 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.2 4.7 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.2 1.7 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 2.7 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 9.6 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 2.3 REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 2.7 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.1 2.7 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.1 1.6 REACTOME_MICRORNA_MIRNA_BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 2.6 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.1 1.3 REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 2.0 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 0.3 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 2.0 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 2.3 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 4.0 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.5 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 1.8 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 3.7 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.7 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.6 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.0 REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.4 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.6 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.9 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.8 REACTOME_GENERIC_TRANSCRIPTION_PATHWAY Genes involved in Generic Transcription Pathway
0.0 1.1 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production