Motif ID: Meis2

Z-value: 1.096


Transcription factors associated with Meis2:

Gene SymbolEntrez IDGene Name
Meis2 ENSMUSG00000027210.14 Meis2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Meis2mm10_v2_chr2_-_116065798_1160658530.352.4e-02Click!


Activity profile for motif Meis2.

activity profile for motif Meis2


Sorted Z-values histogram for motif Meis2

Sorted Z-values for motif Meis2



Network of associatons between targets according to the STRING database.



First level regulatory network of Meis2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_48959089 5.297 ENSMUST00000183659.1
Nav2
neuron navigator 2
chr4_+_128058962 4.824 ENSMUST00000184063.1
Csmd2
CUB and Sushi multiple domains 2
chr15_-_100599864 4.167 ENSMUST00000177247.2
ENSMUST00000177505.2
Pou6f1

POU domain, class 6, transcription factor 1

chr8_+_120114144 4.017 ENSMUST00000108948.1
ENSMUST00000034281.6
ENSMUST00000108951.1
6430548M08Rik


RIKEN cDNA 6430548M08 gene


chr1_+_194619815 3.989 ENSMUST00000027952.5
Plxna2
plexin A2
chr1_+_156558759 3.905 ENSMUST00000173929.1
Abl2
v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene)
chr5_-_25498748 3.871 ENSMUST00000173174.1
Kmt2c
lysine (K)-specific methyltransferase 2C
chr6_-_121081589 3.783 ENSMUST00000077159.5
Mical3
microtubule associated monooxygenase, calponin and LIM domain containing 3
chr5_-_100159261 3.751 ENSMUST00000139520.1
Tmem150c
transmembrane protein 150C
chr17_+_8924109 3.695 ENSMUST00000149440.1
Pde10a
phosphodiesterase 10A
chr5_-_25498702 3.630 ENSMUST00000173073.1
ENSMUST00000045291.7
Kmt2c

lysine (K)-specific methyltransferase 2C

chr3_-_127499095 3.573 ENSMUST00000182594.1
Ank2
ankyrin 2, brain
chr9_-_121495678 3.405 ENSMUST00000035120.4
Cck
cholecystokinin
chr16_+_11322876 3.211 ENSMUST00000180792.1
Snx29
sorting nexin 29
chr19_-_57197435 3.163 ENSMUST00000111550.1
Ablim1
actin-binding LIM protein 1
chr2_-_7395879 3.162 ENSMUST00000182404.1
Celf2
CUGBP, Elav-like family member 2
chr19_-_57197377 3.113 ENSMUST00000111546.1
Ablim1
actin-binding LIM protein 1
chr4_+_42922253 3.096 ENSMUST00000139100.1
N28178
expressed sequence N28178
chr16_+_11322915 3.089 ENSMUST00000115814.3
Snx29
sorting nexin 29
chr9_-_114933811 3.069 ENSMUST00000084853.3
Gpd1l
glycerol-3-phosphate dehydrogenase 1-like
chr19_-_57197496 3.017 ENSMUST00000111544.1
Ablim1
actin-binding LIM protein 1
chr9_+_67840386 2.990 ENSMUST00000077879.5
Vps13c
vacuolar protein sorting 13C (yeast)
chr3_-_107518001 2.989 ENSMUST00000169449.1
ENSMUST00000029499.8
Slc6a17

solute carrier family 6 (neurotransmitter transporter), member 17

chr18_+_36939178 2.900 ENSMUST00000115662.2
Pcdha2
protocadherin alpha 2
chr3_-_84270782 2.891 ENSMUST00000054990.4
Trim2
tripartite motif-containing 2
chr2_-_20943413 2.831 ENSMUST00000140230.1
Arhgap21
Rho GTPase activating protein 21
chr2_+_29124106 2.783 ENSMUST00000129544.1
Setx
senataxin
chr16_+_21891969 2.781 ENSMUST00000042065.6
Map3k13
mitogen-activated protein kinase kinase kinase 13
chr16_-_43979050 2.574 ENSMUST00000165648.1
ENSMUST00000036321.7
Zdhhc23

zinc finger, DHHC domain containing 23

chr1_-_52817503 2.565 ENSMUST00000162576.1
Inpp1
inositol polyphosphate-1-phosphatase
chr7_+_43562256 2.530 ENSMUST00000107972.1
Zfp658
zinc finger protein 658
chr18_+_63708689 2.514 ENSMUST00000072726.5
Wdr7
WD repeat domain 7
chr4_+_107802277 2.438 ENSMUST00000106733.2
ENSMUST00000030356.3
ENSMUST00000106732.2
ENSMUST00000126573.1
Lrp8



low density lipoprotein receptor-related protein 8, apolipoprotein e receptor



chr19_-_57197556 2.400 ENSMUST00000099294.2
Ablim1
actin-binding LIM protein 1
chr5_+_105732063 2.371 ENSMUST00000154807.1
Lrrc8d
leucine rich repeat containing 8D
chr2_-_7396192 2.321 ENSMUST00000137733.2
Celf2
CUGBP, Elav-like family member 2
chr3_+_146852359 2.261 ENSMUST00000038090.5
ENSMUST00000170055.1
Ttll7

tubulin tyrosine ligase-like family, member 7

chr10_-_78244602 2.260 ENSMUST00000000384.6
Trappc10
trafficking protein particle complex 10
chr2_+_158667119 2.249 ENSMUST00000045503.4
Ppp1r16b
protein phosphatase 1, regulatory (inhibitor) subunit 16B
chr1_-_52727457 2.243 ENSMUST00000156876.1
ENSMUST00000087701.3
Mfsd6

major facilitator superfamily domain containing 6

chr7_-_131410325 2.221 ENSMUST00000154602.1
Ikzf5
IKAROS family zinc finger 5
chr5_-_138619653 2.214 ENSMUST00000129832.1
Zfp68
zinc finger protein 68
chr1_-_158814469 2.199 ENSMUST00000161589.2
Pappa2
pappalysin 2
chr8_-_41041828 2.184 ENSMUST00000051379.7
Mtus1
mitochondrial tumor suppressor 1
chr2_-_31116289 2.177 ENSMUST00000149196.1
Fnbp1
formin binding protein 1
chr19_+_42247544 2.164 ENSMUST00000122375.1
Golga7b
golgi autoantigen, golgin subfamily a, 7B
chr16_-_45158624 2.156 ENSMUST00000180636.1
Slc35a5
solute carrier family 35, member A5
chr5_-_107869153 2.130 ENSMUST00000128723.1
ENSMUST00000124034.1
Evi5

ecotropic viral integration site 5

chr5_+_105731755 2.084 ENSMUST00000127686.1
Lrrc8d
leucine rich repeat containing 8D
chr7_+_144175513 2.075 ENSMUST00000105900.1
Shank2
SH3/ankyrin domain gene 2
chr4_+_42091207 2.037 ENSMUST00000178882.1
Gm3893
predicted gene 3893
chr8_-_67910911 2.018 ENSMUST00000093468.5
Psd3
pleckstrin and Sec7 domain containing 3
chr8_+_109868586 1.960 ENSMUST00000179721.1
ENSMUST00000034175.4
Phlpp2

PH domain and leucine rich repeat protein phosphatase 2

chr1_-_6215292 1.951 ENSMUST00000097832.1
4732440D04Rik
RIKEN cDNA 4732440D04 gene
chr1_+_156558844 1.919 ENSMUST00000166172.2
ENSMUST00000027888.6
Abl2

v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene)

chr9_-_114933929 1.919 ENSMUST00000146623.1
Gpd1l
glycerol-3-phosphate dehydrogenase 1-like
chr7_+_12965831 1.916 ENSMUST00000038701.7
Zfp324
zinc finger protein 324
chr8_-_111522073 1.889 ENSMUST00000034437.6
ENSMUST00000038193.7
Wdr59

WD repeat domain 59

chr3_-_89160155 1.877 ENSMUST00000029686.3
Hcn3
hyperpolarization-activated, cyclic nucleotide-gated K+ 3
chr7_+_44590886 1.871 ENSMUST00000107906.3
Kcnc3
potassium voltage gated channel, Shaw-related subfamily, member 3
chr7_+_19176416 1.870 ENSMUST00000117338.1
Eml2
echinoderm microtubule associated protein like 2
chr9_-_86880414 1.864 ENSMUST00000074501.5
ENSMUST00000098495.3
ENSMUST00000074468.6
ENSMUST00000036347.6
Snap91



synaptosomal-associated protein 91



chr2_+_3713478 1.832 ENSMUST00000115053.2
Fam107b
family with sequence similarity 107, member B
chr2_+_127008711 1.830 ENSMUST00000110394.1
ENSMUST00000002063.8
Ap4e1

adaptor-related protein complex AP-4, epsilon 1

chr8_-_3279606 1.809 ENSMUST00000091291.4
Insr
insulin receptor
chr3_+_88629499 1.807 ENSMUST00000175745.1
Arhgef2
rho/rac guanine nucleotide exchange factor (GEF) 2
chr15_-_89128634 1.802 ENSMUST00000082197.5
Hdac10
histone deacetylase 10
chr3_-_152982240 1.785 ENSMUST00000044278.5
St6galnac5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr2_+_32288317 1.772 ENSMUST00000131712.1
ENSMUST00000133113.1
ENSMUST00000081670.6
ENSMUST00000147707.1
ENSMUST00000129193.1
Golga2




golgi autoantigen, golgin subfamily a, 2




chr9_+_32116040 1.770 ENSMUST00000174641.1
Arhgap32
Rho GTPase activating protein 32
chr1_+_34851832 1.759 ENSMUST00000152654.1
Plekhb2
pleckstrin homology domain containing, family B (evectins) member 2
chr3_+_88629442 1.751 ENSMUST00000176316.1
ENSMUST00000176879.1
Arhgef2

rho/rac guanine nucleotide exchange factor (GEF) 2

chr9_-_108079255 1.732 ENSMUST00000162516.1
Rnf123
ring finger protein 123
chr1_+_180111339 1.719 ENSMUST00000145181.1
Cdc42bpa
CDC42 binding protein kinase alpha
chr3_-_146812951 1.718 ENSMUST00000102515.3
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr11_+_55213783 1.686 ENSMUST00000108867.1
Slc36a1
solute carrier family 36 (proton/amino acid symporter), member 1
chr2_-_121271315 1.681 ENSMUST00000131245.1
Trp53bp1
transformation related protein 53 binding protein 1
chr2_+_71981184 1.676 ENSMUST00000090826.5
ENSMUST00000102698.3
Rapgef4

Rap guanine nucleotide exchange factor (GEF) 4

chr17_-_78835326 1.669 ENSMUST00000097281.2
Heatr5b
HEAT repeat containing 5B
chrX_+_71364901 1.663 ENSMUST00000132837.1
Mtmr1
myotubularin related protein 1
chr7_+_125707893 1.663 ENSMUST00000069660.6
ENSMUST00000142464.1
D430042O09Rik

RIKEN cDNA D430042O09 gene

chr7_+_25221417 1.638 ENSMUST00000055604.4
Zfp526
zinc finger protein 526
chr4_-_129440800 1.604 ENSMUST00000053042.5
ENSMUST00000106046.1
Zbtb8b

zinc finger and BTB domain containing 8b

chr19_+_11965817 1.579 ENSMUST00000025590.9
Osbp
oxysterol binding protein
chr5_-_138619702 1.565 ENSMUST00000063262.4
Zfp68
zinc finger protein 68
chr7_+_125707945 1.561 ENSMUST00000148701.1
D430042O09Rik
RIKEN cDNA D430042O09 gene
chr11_+_55204319 1.518 ENSMUST00000108872.2
ENSMUST00000147506.1
ENSMUST00000020499.7
Slc36a1


solute carrier family 36 (proton/amino acid symporter), member 1


chr6_-_106800051 1.499 ENSMUST00000013882.7
ENSMUST00000049675.4
ENSMUST00000113239.3
Crbn


cereblon


chr16_+_44173271 1.494 ENSMUST00000088356.4
ENSMUST00000169582.1
Gm608

predicted gene 608

chr9_-_121705465 1.492 ENSMUST00000111560.2
ENSMUST00000154978.1
Sec22c

SEC22 vesicle trafficking protein homolog C (S. cerevisiae)

chr16_-_45158453 1.489 ENSMUST00000181750.1
Slc35a5
solute carrier family 35, member A5
chr13_+_23934434 1.486 ENSMUST00000072391.1
Hist1h2aa
histone cluster 1, H2aa
chr11_+_109650574 1.485 ENSMUST00000106676.1
Prkar1a
protein kinase, cAMP dependent regulatory, type I, alpha
chr7_+_141949846 1.472 ENSMUST00000172652.1
Brsk2
BR serine/threonine kinase 2
chr5_-_123572976 1.470 ENSMUST00000031388.8
Vps33a
vacuolar protein sorting 33A (yeast)
chr2_+_158666690 1.459 ENSMUST00000103116.3
Ppp1r16b
protein phosphatase 1, regulatory (inhibitor) subunit 16B
chr13_+_63815240 1.457 ENSMUST00000021926.5
ENSMUST00000095724.3
ENSMUST00000143449.1
ENSMUST00000067821.5
Ercc6l2



excision repair cross-complementing rodent repair deficiency, complementation group 6 like 2



chr1_-_52817643 1.450 ENSMUST00000027271.2
Inpp1
inositol polyphosphate-1-phosphatase
chr16_-_45158566 1.448 ENSMUST00000181177.1
Slc35a5
solute carrier family 35, member A5
chr2_+_164823001 1.438 ENSMUST00000132282.1
Zswim1
zinc finger SWIM-type containing 1
chr3_-_95015416 1.422 ENSMUST00000132195.1
Zfp687
zinc finger protein 687
chr4_+_42240639 1.416 ENSMUST00000117202.2
Gm10600
predicted gene 10600
chr1_-_121327672 1.410 ENSMUST00000159085.1
ENSMUST00000159125.1
ENSMUST00000161818.1
Insig2


insulin induced gene 2


chr2_-_31141802 1.409 ENSMUST00000073879.5
ENSMUST00000100208.2
ENSMUST00000100207.2
ENSMUST00000113555.1
ENSMUST00000075326.4
ENSMUST00000113552.2
ENSMUST00000136181.1
Fnbp1






formin binding protein 1






chr11_+_120232921 1.403 ENSMUST00000122148.1
ENSMUST00000044985.7
Bahcc1

BAH domain and coiled-coil containing 1

chr7_+_67222544 1.395 ENSMUST00000058771.5
ENSMUST00000179106.1
Lysmd4

LysM, putative peptidoglycan-binding, domain containing 4

chr7_+_83584910 1.393 ENSMUST00000039317.7
ENSMUST00000164944.1
Tmc3

transmembrane channel-like gene family 3

chr10_-_19015347 1.391 ENSMUST00000019997.4
Tnfaip3
tumor necrosis factor, alpha-induced protein 3
chr1_-_193370260 1.383 ENSMUST00000016323.4
Camk1g
calcium/calmodulin-dependent protein kinase I gamma
chr10_-_75797728 1.375 ENSMUST00000139724.1
Gstt1
glutathione S-transferase, theta 1
chr4_-_32923455 1.373 ENSMUST00000035719.4
ENSMUST00000084749.1
Ankrd6

ankyrin repeat domain 6

chr17_+_21423227 1.359 ENSMUST00000165230.1
ENSMUST00000007884.8
ENSMUST00000167749.1
Zfp54


zinc finger protein 54


chr8_-_109737714 1.346 ENSMUST00000093162.3
Atxn1l
ataxin 1-like
chr10_-_75797528 1.340 ENSMUST00000120177.1
Gstt1
glutathione S-transferase, theta 1
chr11_+_70647258 1.301 ENSMUST00000037534.7
Rnf167
ring finger protein 167
chr2_-_132578128 1.295 ENSMUST00000028822.7
Gpcpd1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr2_-_167492826 1.294 ENSMUST00000109211.2
ENSMUST00000057627.9
Spata2

spermatogenesis associated 2

chr1_-_121327734 1.291 ENSMUST00000160968.1
ENSMUST00000162582.1
Insig2

insulin induced gene 2

chr4_+_143412920 1.261 ENSMUST00000132915.1
ENSMUST00000037356.7
Pramef8

PRAME family member 8

chr11_+_53567361 1.254 ENSMUST00000057330.8
ENSMUST00000120613.2
ENSMUST00000173744.1
ENSMUST00000118353.2
Kif3a



kinesin family member 3A



chr10_+_107271827 1.250 ENSMUST00000020057.8
ENSMUST00000105280.3
Lin7a

lin-7 homolog A (C. elegans)

chr17_+_46202740 1.241 ENSMUST00000087031.5
Xpo5
exportin 5
chr3_-_82074639 1.233 ENSMUST00000029635.8
Gucy1b3
guanylate cyclase 1, soluble, beta 3
chr5_+_34761734 1.233 ENSMUST00000080036.2
Htt
huntingtin
chr5_-_109558957 1.231 ENSMUST00000044579.7
Crlf2
cytokine receptor-like factor 2
chr12_-_24493656 1.229 ENSMUST00000073088.2
Gm16372
predicted pseudogene 16372
chr18_+_52767994 1.219 ENSMUST00000025413.7
ENSMUST00000163742.2
ENSMUST00000178011.1
Sncaip


synuclein, alpha interacting protein (synphilin)


chr11_+_72796164 1.208 ENSMUST00000172220.1
Zzef1
zinc finger, ZZ-type with EF hand domain 1
chr2_+_128967383 1.189 ENSMUST00000110320.2
ENSMUST00000110319.2
Zc3h6

zinc finger CCCH type containing 6

chr11_+_83964419 1.164 ENSMUST00000049714.8
ENSMUST00000092834.5
ENSMUST00000183714.1
ENSMUST00000183456.1
Synrg



synergin, gamma



chr17_-_56717681 1.156 ENSMUST00000164907.1
Vmac
vimentin-type intermediate filament associated coiled-coil protein
chr12_+_64917901 1.146 ENSMUST00000058135.4
Gm527
predicted gene 527
chr17_+_17316078 1.143 ENSMUST00000105311.3
Gm6712
predicted gene 6712
chr2_+_91710852 1.129 ENSMUST00000128140.1
ENSMUST00000140183.1
Harbi1

harbinger transposase derived 1

chr15_+_7129557 1.129 ENSMUST00000067190.5
ENSMUST00000164529.1
Lifr

leukemia inhibitory factor receptor

chr7_+_70388305 1.111 ENSMUST00000080024.5
B130024G19Rik
RIKEN cDNA B130024G19 gene
chr5_-_107972864 1.103 ENSMUST00000153172.1
Fam69a
family with sequence similarity 69, member A
chr18_+_49832622 1.101 ENSMUST00000180611.1
Dmxl1
Dmx-like 1
chr10_-_41303171 1.093 ENSMUST00000043814.3
Fig4
FIG4 homolog (S. cerevisiae)
chrX_-_41911877 1.091 ENSMUST00000047037.8
Thoc2
THO complex 2
chr1_-_156474249 1.085 ENSMUST00000051396.6
Soat1
sterol O-acyltransferase 1
chr16_+_44173239 1.081 ENSMUST00000119746.1
Gm608
predicted gene 608
chr19_-_28967794 1.077 ENSMUST00000162110.1
4430402I18Rik
RIKEN cDNA 4430402I18 gene
chr2_-_132578155 1.075 ENSMUST00000110136.1
ENSMUST00000124107.1
ENSMUST00000060955.5
Gpcpd1


glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)


chr9_+_106448629 1.069 ENSMUST00000048527.7
Abhd14b
abhydrolase domain containing 14b
chr9_+_108991902 1.063 ENSMUST00000147989.1
ENSMUST00000051873.8
Pfkfb4

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4

chr17_-_31519914 1.062 ENSMUST00000167419.1
ENSMUST00000171291.1
Wdr4

WD repeat domain 4

chr3_+_53845086 1.062 ENSMUST00000108014.1
Gm10985
predicted gene 10985
chr2_-_132578244 1.060 ENSMUST00000110142.1
Gpcpd1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr16_+_13780699 1.050 ENSMUST00000023363.6
Rrn3
RRN3 RNA polymerase I transcription factor homolog (yeast)
chr9_-_121704996 1.046 ENSMUST00000078547.4
Sec22c
SEC22 vesicle trafficking protein homolog C (S. cerevisiae)
chr1_+_75436002 1.045 ENSMUST00000131545.1
ENSMUST00000141124.1
Gmppa

GDP-mannose pyrophosphorylase A

chr5_-_138619751 1.042 ENSMUST00000085852.4
ENSMUST00000110905.2
Zfp68

zinc finger protein 68

chr7_-_46795661 1.030 ENSMUST00000123725.1
Hps5
Hermansky-Pudlak syndrome 5 homolog (human)
chr1_-_121327776 1.027 ENSMUST00000160688.1
Insig2
insulin induced gene 2
chr5_-_34187670 1.011 ENSMUST00000042701.6
ENSMUST00000119171.1
Mxd4

Max dimerization protein 4

chr8_+_88697022 1.010 ENSMUST00000043526.8
Cyld
cylindromatosis (turban tumor syndrome)
chr9_+_53771499 1.005 ENSMUST00000048670.8
Slc35f2
solute carrier family 35, member F2
chr7_+_16175085 0.979 ENSMUST00000176342.1
ENSMUST00000177540.1
Meis3

Meis homeobox 3

chr16_-_13903051 0.975 ENSMUST00000115803.1
Pdxdc1
pyridoxal-dependent decarboxylase domain containing 1
chr4_+_155601854 0.952 ENSMUST00000118607.1
Slc35e2
solute carrier family 35, member E2
chr9_-_20385090 0.948 ENSMUST00000068079.7
Zfp560
zinc finger protein 560
chr2_+_158409842 0.941 ENSMUST00000109486.2
ENSMUST00000046274.5
Ralgapb

Ral GTPase activating protein, beta subunit (non-catalytic)

chr2_-_33131645 0.939 ENSMUST00000133135.1
Garnl3
GTPase activating RANGAP domain-like 3
chr2_+_120977017 0.932 ENSMUST00000067582.7
Tmem62
transmembrane protein 62
chr10_-_77418230 0.927 ENSMUST00000020496.7
ENSMUST00000098374.2
ENSMUST00000105406.1
Adarb1


adenosine deaminase, RNA-specific, B1


chr10_+_62980233 0.925 ENSMUST00000131718.1
ENSMUST00000119567.1
ENSMUST00000122231.1
Rufy2


RUN and FYVE domain-containing 2


chr6_+_126939957 0.921 ENSMUST00000032497.3
D6Wsu163e
DNA segment, Chr 6, Wayne State University 163, expressed
chrX_-_103623704 0.899 ENSMUST00000130063.1
ENSMUST00000125419.1
Ftx

Ftx transcript, Xist regulator (non-protein coding)

chr7_-_13009795 0.890 ENSMUST00000051390.7
ENSMUST00000172240.1
Zbtb45

zinc finger and BTB domain containing 45

chr8_-_69184177 0.889 ENSMUST00000185176.1
Lzts1
leucine zipper, putative tumor suppressor 1
chr15_-_83510861 0.884 ENSMUST00000109479.1
ENSMUST00000109480.1
ENSMUST00000016897.4
Ttll1


tubulin tyrosine ligase-like 1


chr11_+_77518566 0.881 ENSMUST00000147386.1
Abhd15
abhydrolase domain containing 15
chr8_-_71725696 0.879 ENSMUST00000153800.1
ENSMUST00000146100.1
Fcho1

FCH domain only 1

chr13_-_8870999 0.873 ENSMUST00000177404.1
ENSMUST00000176922.1
ENSMUST00000021572.4
Wdr37


WD repeat domain 37


chr2_+_3713449 0.867 ENSMUST00000027965.4
Fam107b
family with sequence similarity 107, member B
chr5_+_121660869 0.854 ENSMUST00000111765.1
Brap
BRCA1 associated protein
chr2_-_91649785 0.839 ENSMUST00000111333.1
Zfp408
zinc finger protein 408
chr3_-_110143937 0.828 ENSMUST00000051253.3
Ntng1
netrin G1
chr1_+_96872221 0.828 ENSMUST00000181489.1
Gm5101
predicted gene 5101
chr17_-_24141542 0.825 ENSMUST00000115411.1
ENSMUST00000115409.2
ENSMUST00000115407.2
ENSMUST00000102927.3
Pdpk1



3-phosphoinositide dependent protein kinase 1



chr17_+_35236556 0.823 ENSMUST00000068261.8
Atp6v1g2
ATPase, H+ transporting, lysosomal V1 subunit G2
chr15_-_88819279 0.818 ENSMUST00000043087.8
ENSMUST00000162183.1
Alg12

asparagine-linked glycosylation 12 (alpha-1,6-mannosyltransferase)

chr9_-_122310921 0.814 ENSMUST00000180685.1
Gm26797
predicted gene, 26797
chr12_-_27160311 0.813 ENSMUST00000182473.1
ENSMUST00000177636.1
ENSMUST00000183238.1
Gm9866


predicted gene 9866


chr17_+_26202946 0.811 ENSMUST00000122058.1
ENSMUST00000025020.5
Rgs11

regulator of G-protein signaling 11

chr18_+_80255227 0.806 ENSMUST00000123750.1
Pqlc1
PQ loop repeat containing 1
chr2_+_91650169 0.806 ENSMUST00000090614.4
Arhgap1
Rho GTPase activating protein 1
chr1_-_16770138 0.806 ENSMUST00000071842.8
Gm5828
predicted gene 5828
chr8_+_25601591 0.805 ENSMUST00000155861.1
Whsc1l1
Wolf-Hirschhorn syndrome candidate 1-like 1 (human)
chr5_-_52669677 0.800 ENSMUST00000031069.6
Sepsecs
Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
chr8_-_70234097 0.797 ENSMUST00000130319.1
Armc6
armadillo repeat containing 6
chr11_-_83578496 0.794 ENSMUST00000019266.5
Ccl9
chemokine (C-C motif) ligand 9
chr11_-_46312220 0.789 ENSMUST00000129474.1
ENSMUST00000093166.4
ENSMUST00000165599.2
Cyfip2


cytoplasmic FMR1 interacting protein 2


chr4_+_41966058 0.780 ENSMUST00000108026.2
Gm20938
predicted gene, 20938
chr6_-_87672142 0.772 ENSMUST00000032130.2
ENSMUST00000065997.2
Aplf

aprataxin and PNKP like factor

chr16_-_91728975 0.770 ENSMUST00000073466.6
Cryzl1
crystallin, zeta (quinone reductase)-like 1
chr9_+_120539801 0.768 ENSMUST00000047687.7
Entpd3
ectonucleoside triphosphate diphosphohydrolase 3
chr1_-_193130201 0.758 ENSMUST00000085555.1
Diexf
digestive organ expansion factor homolog (zebrafish)
chr2_-_7395968 0.757 ENSMUST00000002176.6
Celf2
CUGBP, Elav-like family member 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
1.3 5.3 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.9 2.8 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
0.9 2.7 GO:0042196 dichloromethane metabolic process(GO:0018900) chlorinated hydrocarbon metabolic process(GO:0042196) halogenated hydrocarbon metabolic process(GO:0042197)
0.8 5.8 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.7 3.7 GO:1903587 negative regulation of peptidyl-serine dephosphorylation(GO:1902309) regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.6 6.2 GO:0015824 proline transport(GO:0015824)
0.6 3.4 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.6 2.8 GO:0051684 maintenance of Golgi location(GO:0051684)
0.6 1.7 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.5 4.0 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.5 1.4 GO:0070428 granuloma formation(GO:0002432) negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070432)
0.4 3.6 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.4 3.0 GO:1901525 negative regulation of macromitophagy(GO:1901525) regulation of mitophagy in response to mitochondrial depolarization(GO:1904923)
0.4 4.2 GO:0098907 regulation of SA node cell action potential(GO:0098907)
0.4 1.3 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.4 1.2 GO:0099548 trans-synaptic signaling by nitric oxide(GO:0099548)
0.4 1.2 GO:1904580 quinolinate biosynthetic process(GO:0019805) regulation of intracellular mRNA localization(GO:1904580)
0.4 1.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.3 1.0 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.3 3.1 GO:0018095 protein polyglutamylation(GO:0018095)
0.3 7.5 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.3 1.2 GO:1900368 regulation of RNA interference(GO:1900368)
0.3 3.4 GO:0032096 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.3 0.9 GO:0061744 adenosine to inosine editing(GO:0006382) motor behavior(GO:0061744)
0.3 1.5 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.3 2.4 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.3 1.9 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.3 1.9 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.3 0.3 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.3 2.4 GO:2000194 regulation of female gonad development(GO:2000194)
0.3 0.8 GO:0051105 regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.3 1.8 GO:0060050 positive regulation of protein glycosylation(GO:0060050) spindle assembly involved in meiosis(GO:0090306)
0.3 1.3 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.2 3.7 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.2 0.6 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.2 3.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.2 1.0 GO:0097343 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.2 2.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.2 2.5 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.2 0.6 GO:0060126 hypophysis morphogenesis(GO:0048850) somatotropin secreting cell differentiation(GO:0060126)
0.2 1.3 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.2 0.9 GO:0060178 regulation of exocyst localization(GO:0060178)
0.2 1.5 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.2 0.6 GO:0071550 regulation of muscle atrophy(GO:0014735) death-inducing signaling complex assembly(GO:0071550)
0.2 0.9 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.2 0.5 GO:0031038 myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519)
0.2 0.5 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.2 1.5 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.2 0.6 GO:0032095 regulation of response to food(GO:0032095)
0.2 1.7 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.2 1.1 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
0.2 1.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.1 1.5 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 0.7 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 2.6 GO:0018345 protein palmitoylation(GO:0018345)
0.1 2.1 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 5.4 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 1.8 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 4.0 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.1 0.4 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 1.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 2.6 GO:0045830 positive regulation of isotype switching(GO:0045830)
0.1 0.5 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 0.6 GO:0071494 cellular response to UV-C(GO:0071494)
0.1 1.1 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 1.6 GO:0044144 regulation of growth of symbiont in host(GO:0044126) modulation of growth of symbiont involved in interaction with host(GO:0044144)
0.1 1.1 GO:0031642 negative regulation of myelination(GO:0031642)
0.1 0.4 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.1 0.4 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1 1.4 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.6 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 0.7 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.8 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.8 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.1 0.5 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.1 0.6 GO:0006020 inositol metabolic process(GO:0006020)
0.1 0.5 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.8 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 0.5 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.1 1.6 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.1 0.8 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 2.0 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.7 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 2.8 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 0.7 GO:0070627 ferrous iron import(GO:0070627)
0.1 2.2 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.1 2.1 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.1 0.6 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.1 0.2 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.1 0.4 GO:0010730 negative regulation of hydrogen peroxide metabolic process(GO:0010727) negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.1 0.6 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.1 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.1 3.8 GO:0030042 actin filament depolymerization(GO:0030042)
0.1 0.5 GO:0060046 regulation of acrosome reaction(GO:0060046)
0.1 1.7 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.1 5.8 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.3 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.1 0.8 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.1 0.2 GO:0006533 aspartate catabolic process(GO:0006533) D-amino acid metabolic process(GO:0046416)
0.1 1.7 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1 0.8 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.1 0.2 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.1 0.2 GO:1904046 seryl-tRNA aminoacylation(GO:0006434) negative regulation of vascular endothelial growth factor production(GO:1904046)
0.1 1.9 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.1 0.4 GO:0046549 retinal cone cell development(GO:0046549)
0.1 0.9 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.1 0.2 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 3.1 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.1 0.5 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.2 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) cellular response to caffeine(GO:0071313)
0.0 0.7 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.7 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 2.4 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0 1.4 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.8 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 2.4 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.8 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.8 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.6 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 5.2 GO:0008643 carbohydrate transport(GO:0008643)
0.0 0.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.1 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0 0.2 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 2.8 GO:0098656 anion transmembrane transport(GO:0098656)
0.0 0.2 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 3.0 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.7 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.0 2.2 GO:0060349 bone morphogenesis(GO:0060349)
0.0 1.8 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.1 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.0 1.9 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.5 GO:0030262 cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.0 0.4 GO:0001782 B cell homeostasis(GO:0001782)
0.0 0.1 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.4 GO:0030307 positive regulation of cell growth(GO:0030307)
0.0 0.3 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 1.0 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.1 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.0 0.4 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.2 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 2.2 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.6 GO:0006821 chloride transport(GO:0006821)
0.0 0.1 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.5 GO:0034614 cellular response to reactive oxygen species(GO:0034614)
0.0 0.5 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 1.4 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.4 GO:0051966 regulation of synaptic transmission, glutamatergic(GO:0051966)
0.0 1.1 GO:0043473 pigmentation(GO:0043473)
0.0 0.1 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.3 GO:0090102 cochlea development(GO:0090102)
0.0 0.5 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.5 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.6 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.0 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.7 3.6 GO:0044316 cone cell pedicle(GO:0044316)
0.6 7.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.6 1.9 GO:0098835 presynaptic endosome(GO:0098830) presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.6 1.8 GO:0005899 insulin receptor complex(GO:0005899)
0.5 3.7 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.4 1.3 GO:0016939 kinesin II complex(GO:0016939)
0.4 1.2 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.3 1.3 GO:0031084 BLOC-2 complex(GO:0031084)
0.3 1.5 GO:0097443 sorting endosome(GO:0097443)
0.3 1.2 GO:0045098 type III intermediate filament(GO:0045098)
0.3 4.6 GO:0005614 interstitial matrix(GO:0005614)
0.3 2.1 GO:0005883 neurofilament(GO:0005883)
0.2 3.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 3.4 GO:0043203 axon hillock(GO:0043203)
0.2 5.8 GO:0001891 phagocytic cup(GO:0001891)
0.2 2.8 GO:0008385 IkappaB kinase complex(GO:0008385)
0.2 1.1 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.2 1.5 GO:0033263 CORVET complex(GO:0033263)
0.2 2.2 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.2 1.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.2 2.0 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.2 1.8 GO:0000137 Golgi cis cisterna(GO:0000137)
0.2 1.5 GO:0070545 PeBoW complex(GO:0070545)
0.1 3.7 GO:0002102 podosome(GO:0002102)
0.1 1.7 GO:0061700 GATOR2 complex(GO:0061700)
0.1 2.1 GO:0030008 TRAPP complex(GO:0030008)
0.1 3.6 GO:0031430 M band(GO:0031430)
0.1 1.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 1.2 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1 0.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.5 GO:0070826 paraferritin complex(GO:0070826)
0.1 1.5 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 1.2 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.1 0.5 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 10.2 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 3.4 GO:0035861 site of double-strand break(GO:0035861)
0.1 6.9 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 1.7 GO:0042641 actomyosin(GO:0042641)
0.1 1.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.6 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 0.9 GO:0097542 ciliary tip(GO:0097542)
0.1 0.7 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 0.6 GO:0031672 A band(GO:0031672)
0.1 2.5 GO:0008021 synaptic vesicle(GO:0008021)
0.1 2.9 GO:0045171 intercellular bridge(GO:0045171)
0.1 1.9 GO:0030673 axolemma(GO:0030673)
0.1 0.8 GO:0044292 dendrite terminus(GO:0044292)
0.1 0.2 GO:0035859 Seh1-associated complex(GO:0035859)
0.1 0.6 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.0 0.2 GO:0070382 exocytic vesicle(GO:0070382)
0.0 2.0 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.8 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.4 GO:0042599 lamellar body(GO:0042599)
0.0 0.1 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 1.2 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.6 GO:0097386 glial cell projection(GO:0097386)
0.0 0.3 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 8.6 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 2.4 GO:0005901 caveola(GO:0005901)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.6 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 7.8 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 0.3 GO:0097228 sperm midpiece(GO:0097225) sperm principal piece(GO:0097228)
0.0 0.4 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.6 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0 0.4 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 1.1 GO:0005811 lipid particle(GO:0005811)
0.0 1.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.2 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.9 GO:0043198 dendritic shaft(GO:0043198)
0.0 11.0 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.9 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.5 GO:0016234 inclusion body(GO:0016234)
0.0 0.8 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.2 GO:0000124 SAGA complex(GO:0000124)
0.0 0.6 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.8 GO:0043204 perikaryon(GO:0043204)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0015173 hydrogen:amino acid symporter activity(GO:0005280) aromatic amino acid transmembrane transporter activity(GO:0015173)
1.0 4.0 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
1.0 5.0 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.9 2.8 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.9 2.7 GO:0019120 hydrolase activity, acting on acid halide bonds(GO:0016824) hydrolase activity, acting on acid halide bonds, in C-halide compounds(GO:0019120) alkylhalidase activity(GO:0047651)
0.9 3.4 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.8 3.1 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.6 2.4 GO:0038025 reelin receptor activity(GO:0038025)
0.5 3.7 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.5 1.9 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.4 7.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.4 1.1 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924)
0.4 1.8 GO:0051425 PTB domain binding(GO:0051425)
0.4 1.1 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.3 1.0 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.3 2.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.3 4.5 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.3 2.0 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.3 2.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.3 4.0 GO:0017154 semaphorin receptor activity(GO:0017154)
0.3 1.5 GO:0070883 pre-miRNA binding(GO:0070883)
0.2 1.7 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.2 0.9 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.2 1.8 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.2 5.1 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.2 1.1 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.2 0.6 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.2 0.6 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.2 1.3 GO:0097016 L27 domain binding(GO:0097016)
0.2 0.6 GO:0016880 acid-ammonia (or amide) ligase activity(GO:0016880)
0.2 0.6 GO:0000992 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.2 0.8 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.2 0.8 GO:0034511 U3 snoRNA binding(GO:0034511)
0.2 3.0 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.2 4.0 GO:0071949 FAD binding(GO:0071949)
0.2 1.2 GO:0034452 dynactin binding(GO:0034452)
0.2 1.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 4.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.2 0.6 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.2 1.9 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.2 0.5 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.6 GO:0035877 death effector domain binding(GO:0035877)
0.1 1.5 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 0.4 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 2.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.4 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 1.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 6.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 2.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 6.2 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 0.5 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.8 GO:0016004 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.1 1.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 0.5 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.1 0.7 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 2.2 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.6 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 4.8 GO:0030507 spectrin binding(GO:0030507)
0.1 0.4 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 1.2 GO:0019215 intermediate filament binding(GO:0019215)
0.1 0.4 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.1 1.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 1.6 GO:0015248 sterol transporter activity(GO:0015248)
0.1 1.7 GO:0030552 cAMP binding(GO:0030552)
0.1 2.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.7 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 2.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.2 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 0.5 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 0.6 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.2 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.1 0.7 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.2 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 1.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.8 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.8 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 4.0 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 2.9 GO:0017022 myosin binding(GO:0017022)
0.0 1.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.8 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.7 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 1.1 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 1.4 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.0 0.8 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 4.1 GO:0008201 heparin binding(GO:0008201)
0.0 6.3 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.8 GO:0008009 chemokine activity(GO:0008009)
0.0 0.1 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.0 0.9 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 4.1 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.6 GO:0043394 proteoglycan binding(GO:0043394)
0.0 1.9 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 1.3 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 8.8 GO:0003779 actin binding(GO:0003779)
0.0 0.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.0 GO:0001034 RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.0 0.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.7 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.1 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 1.1 GO:0005125 cytokine activity(GO:0005125)
0.0 0.6 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 1.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.7 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.1 GO:0017166 vinculin binding(GO:0017166)
0.0 0.0 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.1 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.4 GO:0016859 peptidyl-prolyl cis-trans isomerase activity(GO:0003755) cis-trans isomerase activity(GO:0016859)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.0 PID_REELIN_PATHWAY Reelin signaling pathway
0.1 1.2 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.1 2.1 PID_AURORA_B_PATHWAY Aurora B signaling
0.1 2.3 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.1 2.4 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.1 3.2 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.1 2.8 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
0.1 1.5 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.0 2.6 PID_LKB1_PATHWAY LKB1 signaling events
0.0 1.4 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 1.8 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 1.5 SIG_CHEMOTAXIS Genes related to chemotaxis
0.0 3.8 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.8 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.8 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.8 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.5 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.7 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 1.2 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.5 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.8 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 0.4 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.0 1.0 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 0.5 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.4 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 9.7 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.3 4.0 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 5.8 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.2 4.9 REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.2 5.0 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.1 2.4 REACTOME_PLATELET_SENSITIZATION_BY_LDL Genes involved in Platelet sensitization by LDL
0.1 3.2 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 2.2 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 2.6 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.1 1.6 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 0.5 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 3.2 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 2.4 REACTOME_NOD1_2_SIGNALING_PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 1.1 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 0.8 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 2.2 REACTOME_INTEGRIN_ALPHAIIB_BETA3_SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.1 0.5 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.7 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.4 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 3.5 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.6 REACTOME_CA_DEPENDENT_EVENTS Genes involved in Ca-dependent events
0.0 1.9 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.4 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.3 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 1.6 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.5 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 1.0 REACTOME_RNA_POL_I_TRANSCRIPTION_INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 1.9 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.0 0.8 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 2.2 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.4 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.5 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.3 REACTOME_MICRORNA_MIRNA_BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.4 REACTOME_SPHINGOLIPID_METABOLISM Genes involved in Sphingolipid metabolism
0.0 0.3 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation