Motif ID: Hnf4a

Z-value: 0.844


Transcription factors associated with Hnf4a:

Gene SymbolEntrez IDGene Name
Hnf4a ENSMUSG00000017950.10 Hnf4a



Activity profile for motif Hnf4a.

activity profile for motif Hnf4a


Sorted Z-values histogram for motif Hnf4a

Sorted Z-values for motif Hnf4a



Network of associatons between targets according to the STRING database.



First level regulatory network of Hnf4a

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_+_101840602 5.162 ENSMUST00000159314.1
Lmo7
LIM domain only 7
chr2_-_131042682 4.458 ENSMUST00000028787.5
ENSMUST00000110239.1
ENSMUST00000110234.1
Gfra4


glial cell line derived neurotrophic factor family receptor alpha 4


chr14_+_101840501 4.322 ENSMUST00000159026.1
Lmo7
LIM domain only 7
chr2_-_131043088 3.674 ENSMUST00000110240.3
ENSMUST00000066958.4
ENSMUST00000110235.1
Gfra4


glial cell line derived neurotrophic factor family receptor alpha 4


chr3_-_84305385 3.619 ENSMUST00000122849.1
ENSMUST00000132283.1
Trim2

tripartite motif-containing 2

chr1_-_155417394 3.610 ENSMUST00000111775.1
ENSMUST00000111774.1
Xpr1

xenotropic and polytropic retrovirus receptor 1

chr7_+_25268387 3.462 ENSMUST00000169392.1
Cic
capicua homolog (Drosophila)
chr1_-_77515048 3.116 ENSMUST00000027451.6
Epha4
Eph receptor A4
chr4_+_136286061 3.083 ENSMUST00000069195.4
ENSMUST00000130658.1
Zfp46

zinc finger protein 46

chr11_+_104282371 2.952 ENSMUST00000106988.1
ENSMUST00000106989.1
Mapt

microtubule-associated protein tau

chr15_-_102722120 2.945 ENSMUST00000171838.1
Calcoco1
calcium binding and coiled coil domain 1
chr7_+_112225856 2.842 ENSMUST00000050149.5
ENSMUST00000106647.1
ENSMUST00000106648.1
Mical2


microtubule associated monooxygenase, calponin and LIM domain containing 2


chr5_+_19907774 2.719 ENSMUST00000115267.2
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr8_-_41016295 2.703 ENSMUST00000131965.1
Mtus1
mitochondrial tumor suppressor 1
chr2_+_3704787 2.676 ENSMUST00000115054.2
Fam107b
family with sequence similarity 107, member B
chr15_-_102722150 2.618 ENSMUST00000023818.3
Calcoco1
calcium binding and coiled coil domain 1
chrX_-_105929206 2.594 ENSMUST00000134381.1
ENSMUST00000154866.1
Atrx

alpha thalassemia/mental retardation syndrome X-linked homolog (human)

chr15_+_3270767 2.536 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
Sepp1



selenoprotein P, plasma, 1



chr6_-_41636389 2.526 ENSMUST00000031902.5
Trpv6
transient receptor potential cation channel, subfamily V, member 6
chrX_-_105929333 2.513 ENSMUST00000134507.1
ENSMUST00000137453.1
ENSMUST00000150914.1
Atrx


alpha thalassemia/mental retardation syndrome X-linked homolog (human)


chr7_+_45896941 2.507 ENSMUST00000069772.7
ENSMUST00000107716.1
Tmem143

transmembrane protein 143

chr4_+_126609818 2.503 ENSMUST00000097886.3
ENSMUST00000164362.1
5730409E04Rik

RIKEN cDNA 5730409E04Rik gene

chr3_+_107877227 2.462 ENSMUST00000037375.8
Eps8l3
EPS8-like 3
chr3_-_84304762 2.414 ENSMUST00000107692.1
Trim2
tripartite motif-containing 2
chr18_-_79109391 2.401 ENSMUST00000025430.8
ENSMUST00000161465.2
Setbp1

SET binding protein 1

chr6_+_86195214 2.393 ENSMUST00000032066.9
Tgfa
transforming growth factor alpha
chr8_-_113848615 2.374 ENSMUST00000093113.4
Adamts18
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18
chr17_-_91088726 2.279 ENSMUST00000072671.7
ENSMUST00000174331.1
ENSMUST00000161402.3
ENSMUST00000054059.8
Nrxn1



neurexin I



chr7_+_67222544 2.277 ENSMUST00000058771.5
ENSMUST00000179106.1
Lysmd4

LysM, putative peptidoglycan-binding, domain containing 4

chr13_-_41273977 2.207 ENSMUST00000163881.1
Gm17364
predicted gene, 17364
chr16_-_34513944 2.064 ENSMUST00000151491.1
ENSMUST00000114960.2
Kalrn

kalirin, RhoGEF kinase

chr1_-_155417283 2.061 ENSMUST00000027741.5
Xpr1
xenotropic and polytropic retrovirus receptor 1
chr15_+_82252397 2.034 ENSMUST00000136948.1
1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr11_-_77894096 1.921 ENSMUST00000017597.4
Pipox
pipecolic acid oxidase
chr16_-_34514084 1.896 ENSMUST00000089655.5
Kalrn
kalirin, RhoGEF kinase
chr2_+_130406478 1.850 ENSMUST00000055421.4
Tmem239
transmembrane 239
chr4_-_118409219 1.807 ENSMUST00000075406.5
Szt2
seizure threshold 2
chr1_-_55226768 1.780 ENSMUST00000027121.8
ENSMUST00000114428.2
Rftn2

raftlin family member 2

chr19_+_44992127 1.750 ENSMUST00000179305.1
Sema4g
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr6_+_113282302 1.735 ENSMUST00000041203.5
Cpne9
copine family member IX
chr3_-_108085346 1.708 ENSMUST00000078912.5
Ampd2
adenosine monophosphate deaminase 2
chr1_+_132008285 1.699 ENSMUST00000146432.1
Elk4
ELK4, member of ETS oncogene family
chr10_-_13552838 1.692 ENSMUST00000105541.1
Pex3
peroxisomal biogenesis factor 3
chr5_+_117120120 1.600 ENSMUST00000111978.1
Taok3
TAO kinase 3
chr15_+_102150502 1.586 ENSMUST00000023806.6
Soat2
sterol O-acyltransferase 2
chr6_+_125145235 1.583 ENSMUST00000119527.1
ENSMUST00000088276.6
ENSMUST00000051171.7
ENSMUST00000117675.1
Iffo1



intermediate filament family orphan 1



chr7_+_45897429 1.568 ENSMUST00000140243.1
Tmem143
transmembrane protein 143
chr9_+_118506226 1.479 ENSMUST00000084820.4
Golga4
golgi autoantigen, golgin subfamily a, 4
chrX_-_105929397 1.456 ENSMUST00000113573.1
ENSMUST00000130980.1
Atrx

alpha thalassemia/mental retardation syndrome X-linked homolog (human)

chr11_-_61267177 1.425 ENSMUST00000066277.3
ENSMUST00000074127.7
ENSMUST00000108715.2
Aldh3a2


aldehyde dehydrogenase family 3, subfamily A2


chr11_+_55213783 1.412 ENSMUST00000108867.1
Slc36a1
solute carrier family 36 (proton/amino acid symporter), member 1
chr17_+_55445375 1.411 ENSMUST00000133899.1
ENSMUST00000086878.3
St6gal2

beta galactoside alpha 2,6 sialyltransferase 2

chr13_+_67833235 1.398 ENSMUST00000060609.7
Gm10037
predicted gene 10037
chr19_-_45998479 1.382 ENSMUST00000045396.7
9130011E15Rik
RIKEN cDNA 9130011E15 gene
chr7_-_110614761 1.342 ENSMUST00000166020.1
ENSMUST00000171218.1
ENSMUST00000033058.7
ENSMUST00000164759.1
Sbf2



SET binding factor 2



chr8_-_13200576 1.340 ENSMUST00000165605.2
Grtp1
GH regulated TBC protein 1
chr9_-_44288332 1.304 ENSMUST00000161408.1
Abcg4
ATP-binding cassette, sub-family G (WHITE), member 4
chr6_-_86765807 1.283 ENSMUST00000123732.1
Anxa4
annexin A4
chr5_+_19907502 1.238 ENSMUST00000101558.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr19_+_4594312 1.236 ENSMUST00000113825.2
Pcx
pyruvate carboxylase
chr16_+_8513429 1.228 ENSMUST00000065987.7
ENSMUST00000115838.1
ENSMUST00000115839.2
Abat


4-aminobutyrate aminotransferase


chr7_+_66689889 1.225 ENSMUST00000153007.1
ENSMUST00000177726.1
ENSMUST00000121777.2
ENSMUST00000150071.1
ENSMUST00000077967.6
Lins




lines homolog (Drosophila)




chr11_+_78499087 1.219 ENSMUST00000017488.4
Vtn
vitronectin
chr9_+_58582240 1.219 ENSMUST00000177292.1
ENSMUST00000085651.5
Nptn

neuroplastin

chr2_-_130638094 1.208 ENSMUST00000089561.3
ENSMUST00000110260.1
Lzts3

leucine zipper, putative tumor suppressor family member 3

chr8_+_12915879 1.208 ENSMUST00000110876.2
ENSMUST00000110879.2
Mcf2l

mcf.2 transforming sequence-like

chr15_+_12117848 1.192 ENSMUST00000128475.1
ENSMUST00000134277.1
Zfr

zinc finger RNA binding protein

chr17_-_35909626 1.189 ENSMUST00000141132.1
Atat1
alpha tubulin acetyltransferase 1
chr4_-_119538769 1.151 ENSMUST00000079611.6
AA415398
expressed sequence AA415398
chr8_+_84990585 1.151 ENSMUST00000064495.6
Hook2
hook homolog 2 (Drosophila)
chr10_-_128919259 1.117 ENSMUST00000149961.1
ENSMUST00000026406.7
Rdh5

retinol dehydrogenase 5

chr19_+_46356880 1.083 ENSMUST00000086969.6
ENSMUST00000128455.1
Tmem180

transmembrane protein 180

chr19_+_46152505 1.082 ENSMUST00000026254.7
Gbf1
golgi-specific brefeldin A-resistance factor 1
chr9_-_57147034 1.081 ENSMUST00000034842.4
Neil1
nei endonuclease VIII-like 1 (E. coli)
chr5_+_30232581 1.069 ENSMUST00000145167.1
Ept1
ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
chr7_-_67222412 1.041 ENSMUST00000181631.1
1700112J16Rik
RIKEN cDNA 1700112J16 gene
chrX_-_95166307 1.028 ENSMUST00000113873.2
ENSMUST00000113876.2
ENSMUST00000113885.1
ENSMUST00000113883.1
ENSMUST00000182001.1
ENSMUST00000113882.1
ENSMUST00000113878.1
ENSMUST00000182562.1
Arhgef9







CDC42 guanine nucleotide exchange factor (GEF) 9







chr17_-_25785324 1.014 ENSMUST00000150324.1
Haghl
hydroxyacylglutathione hydrolase-like
chr8_-_83594440 1.000 ENSMUST00000019382.9
ENSMUST00000165740.1
Tecr

trans-2,3-enoyl-CoA reductase

chr6_-_86765866 0.985 ENSMUST00000113675.1
Anxa4
annexin A4
chr8_+_13037308 0.965 ENSMUST00000063820.5
ENSMUST00000033821.4
F10

coagulation factor X

chr9_-_44288535 0.952 ENSMUST00000161354.1
Abcg4
ATP-binding cassette, sub-family G (WHITE), member 4
chrX_+_6415736 0.940 ENSMUST00000143641.3
Shroom4
shroom family member 4
chr17_+_34604262 0.940 ENSMUST00000174041.1
Agpat1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr4_-_138326234 0.935 ENSMUST00000105817.3
ENSMUST00000030536.6
Pink1

PTEN induced putative kinase 1

chr4_-_42084291 0.914 ENSMUST00000177937.1
Gm21968
predicted gene, 21968
chr11_+_74649462 0.909 ENSMUST00000092915.5
ENSMUST00000117818.1
Cluh

clustered mitochondria (cluA/CLU1) homolog

chr16_-_34095983 0.881 ENSMUST00000114973.1
ENSMUST00000114964.1
Kalrn

kalirin, RhoGEF kinase

chr8_-_83594405 0.878 ENSMUST00000163837.1
Tecr
trans-2,3-enoyl-CoA reductase
chr10_-_60752773 0.858 ENSMUST00000117513.1
ENSMUST00000119595.1
Slc29a3

solute carrier family 29 (nucleoside transporters), member 3

chr2_-_77170592 0.856 ENSMUST00000164114.2
ENSMUST00000049544.7
Ccdc141

coiled-coil domain containing 141

chrX_-_162565514 0.847 ENSMUST00000154424.1
Reps2
RALBP1 associated Eps domain containing protein 2
chr12_-_93929102 0.829 ENSMUST00000180321.1
Gm9726
predicted gene 9726
chr1_-_52190901 0.823 ENSMUST00000156887.1
ENSMUST00000129107.1
Gls

glutaminase

chr2_+_71117923 0.817 ENSMUST00000028403.2
Cybrd1
cytochrome b reductase 1
chr10_-_128744014 0.817 ENSMUST00000026414.7
Dgka
diacylglycerol kinase, alpha
chr5_-_103977360 0.781 ENSMUST00000048118.8
Hsd17b13
hydroxysteroid (17-beta) dehydrogenase 13
chr3_+_96830069 0.772 ENSMUST00000058865.7
Pdzk1
PDZ domain containing 1
chr19_+_44203265 0.769 ENSMUST00000026220.5
Scd3
stearoyl-coenzyme A desaturase 3
chr7_+_28833975 0.741 ENSMUST00000066723.8
Lgals4
lectin, galactose binding, soluble 4
chr5_-_66514815 0.735 ENSMUST00000161879.1
ENSMUST00000159357.1
Apbb2

amyloid beta (A4) precursor protein-binding, family B, member 2

chr4_+_110397661 0.723 ENSMUST00000106589.2
ENSMUST00000106587.2
ENSMUST00000106591.1
ENSMUST00000106592.1
Agbl4



ATP/GTP binding protein-like 4



chr3_+_95134088 0.722 ENSMUST00000066386.5
Lysmd1
LysM, putative peptidoglycan-binding, domain containing 1
chr9_-_58249702 0.713 ENSMUST00000135310.1
ENSMUST00000085673.4
ENSMUST00000114136.2
ENSMUST00000153820.1
ENSMUST00000124982.1
Pml




promyelocytic leukemia




chr12_-_79192248 0.709 ENSMUST00000161204.1
Rdh11
retinol dehydrogenase 11
chr4_-_132422394 0.686 ENSMUST00000152271.1
ENSMUST00000084170.5
Phactr4

phosphatase and actin regulator 4

chr16_-_22439719 0.681 ENSMUST00000079601.6
Etv5
ets variant gene 5
chr6_+_124663027 0.681 ENSMUST00000004381.7
Lpcat3
lysophosphatidylcholine acyltransferase 3
chr9_+_96196246 0.648 ENSMUST00000165120.2
ENSMUST00000034982.9
Tfdp2

transcription factor Dp 2

chr15_-_100424208 0.646 ENSMUST00000154331.1
Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr2_-_158028423 0.644 ENSMUST00000029179.4
Tti1
TELO2 interacting protein 1
chr17_-_35910032 0.638 ENSMUST00000141662.1
ENSMUST00000056034.6
ENSMUST00000077494.6
ENSMUST00000149277.1
ENSMUST00000061052.5
Atat1




alpha tubulin acetyltransferase 1




chr3_+_7612702 0.632 ENSMUST00000181286.1
Gm16685
predicted gene, 16685
chr2_+_158028733 0.631 ENSMUST00000152452.1
Rprd1b
regulation of nuclear pre-mRNA domain containing 1B
chr17_-_45592262 0.602 ENSMUST00000164769.1
Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr16_+_14580221 0.599 ENSMUST00000147024.1
A630010A05Rik
RIKEN cDNA A630010A05 gene
chr2_-_59160644 0.589 ENSMUST00000077687.5
Ccdc148
coiled-coil domain containing 148
chr8_-_121944886 0.587 ENSMUST00000057653.7
Car5a
carbonic anhydrase 5a, mitochondrial
chrX_-_73659724 0.574 ENSMUST00000114473.1
ENSMUST00000002087.7
Pnck

pregnancy upregulated non-ubiquitously expressed CaM kinase

chr18_+_63708689 0.565 ENSMUST00000072726.5
Wdr7
WD repeat domain 7
chr17_-_45592569 0.560 ENSMUST00000163492.1
Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr17_-_80480435 0.559 ENSMUST00000068714.5
Sos1
son of sevenless homolog 1 (Drosophila)
chr11_+_3895223 0.557 ENSMUST00000055931.4
ENSMUST00000109996.1
Dusp18

dual specificity phosphatase 18

chr2_+_92375306 0.537 ENSMUST00000028650.8
Pex16
peroxisomal biogenesis factor 16
chrX_-_73660047 0.533 ENSMUST00000114472.1
Pnck
pregnancy upregulated non-ubiquitously expressed CaM kinase
chr4_+_131873608 0.501 ENSMUST00000053819.3
Srsf4
serine/arginine-rich splicing factor 4
chr7_-_4725082 0.499 ENSMUST00000086363.4
ENSMUST00000086364.4
Tmem150b

transmembrane protein 150B

chr2_+_25500750 0.494 ENSMUST00000015239.3
Fbxw5
F-box and WD-40 domain protein 5
chr4_+_110397764 0.489 ENSMUST00000097920.2
ENSMUST00000080744.6
Agbl4

ATP/GTP binding protein-like 4

chrX_-_150814265 0.484 ENSMUST00000026302.6
ENSMUST00000129768.1
ENSMUST00000112699.2
Maged2


melanoma antigen, family D, 2


chr3_-_79628660 0.479 ENSMUST00000120992.1
Etfdh
electron transferring flavoprotein, dehydrogenase
chr7_-_28598140 0.479 ENSMUST00000108283.1
ENSMUST00000040531.8
Pak4
Samd4b
p21 protein (Cdc42/Rac)-activated kinase 4
sterile alpha motif domain containing 4B
chr5_-_24447587 0.471 ENSMUST00000127194.1
ENSMUST00000115033.1
ENSMUST00000123167.1
ENSMUST00000030799.8
Tmub1



transmembrane and ubiquitin-like domain containing 1



chr19_+_5088534 0.465 ENSMUST00000025811.4
Yif1a
Yip1 interacting factor homolog A (S. cerevisiae)
chr17_-_45592485 0.438 ENSMUST00000166119.1
Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr19_-_6921753 0.436 ENSMUST00000173635.1
Esrra
estrogen related receptor, alpha
chrX_+_48108912 0.432 ENSMUST00000114998.1
ENSMUST00000115000.3
Xpnpep2

X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound

chr3_-_121815212 0.427 ENSMUST00000029770.5
Abcd3
ATP-binding cassette, sub-family D (ALD), member 3
chr11_-_69413675 0.425 ENSMUST00000094077.4
Kdm6b
KDM1 lysine (K)-specific demethylase 6B
chr17_-_26021853 0.423 ENSMUST00000118828.1
Rab11fip3
RAB11 family interacting protein 3 (class II)
chr11_+_87592897 0.412 ENSMUST00000119628.1
Mtmr4
myotubularin related protein 4
chr11_+_105967938 0.404 ENSMUST00000001963.7
Ace
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr11_+_4986824 0.403 ENSMUST00000009234.9
ENSMUST00000109897.1
Ap1b1

adaptor protein complex AP-1, beta 1 subunit

chr1_+_85894281 0.372 ENSMUST00000027425.9
Itm2c
integral membrane protein 2C
chr9_-_77347816 0.361 ENSMUST00000184138.1
ENSMUST00000184006.1
ENSMUST00000185144.1
ENSMUST00000034910.9
Mlip



muscular LMNA-interacting protein



chr5_+_31698050 0.347 ENSMUST00000114507.3
ENSMUST00000063813.4
ENSMUST00000071531.5
ENSMUST00000131995.1
Bre



brain and reproductive organ-expressed protein



chr12_-_67222549 0.344 ENSMUST00000037181.8
Mdga2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr17_+_32621319 0.342 ENSMUST00000077639.5
Gm9705
predicted gene 9705
chr5_+_31697960 0.329 ENSMUST00000114515.2
Bre
brain and reproductive organ-expressed protein
chr2_-_27248335 0.322 ENSMUST00000139312.1
Sardh
sarcosine dehydrogenase
chr3_-_107696462 0.313 ENSMUST00000029490.8
Ahcyl1
S-adenosylhomocysteine hydrolase-like 1
chr17_-_36129425 0.301 ENSMUST00000046131.9
ENSMUST00000173322.1
ENSMUST00000172968.1
Gm7030


predicted gene 7030


chr11_+_103774150 0.297 ENSMUST00000000127.5
Wnt3
wingless-related MMTV integration site 3
chr16_-_16560201 0.291 ENSMUST00000162045.1
ENSMUST00000162124.1
ENSMUST00000161861.1
Fgd4


FYVE, RhoGEF and PH domain containing 4


chr17_-_46202576 0.288 ENSMUST00000024749.7
Polh
polymerase (DNA directed), eta (RAD 30 related)
chr2_+_164805082 0.273 ENSMUST00000052107.4
Zswim3
zinc finger SWIM-type containing 3
chr16_-_16560046 0.271 ENSMUST00000172181.2
Fgd4
FYVE, RhoGEF and PH domain containing 4
chr3_+_118562129 0.270 ENSMUST00000039177.7
Dpyd
dihydropyrimidine dehydrogenase
chr6_-_122602345 0.267 ENSMUST00000147760.1
ENSMUST00000112585.1
Apobec1

apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1

chr5_+_31697665 0.258 ENSMUST00000080598.7
Bre
brain and reproductive organ-expressed protein
chr19_-_10604258 0.247 ENSMUST00000037678.6
Dak
dihydroxyacetone kinase 2 homolog (yeast)
chr6_-_122602404 0.240 ENSMUST00000112586.1
Apobec1
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
chr1_+_135132693 0.238 ENSMUST00000049449.4
Ptpn7
protein tyrosine phosphatase, non-receptor type 7
chr14_-_41006882 0.236 ENSMUST00000152837.1
ENSMUST00000134715.1
Fam213a

family with sequence similarity 213, member A

chr11_-_81968415 0.227 ENSMUST00000066197.6
Asic2
acid-sensing (proton-gated) ion channel 2
chr9_+_22003035 0.224 ENSMUST00000115331.2
ENSMUST00000003493.7
Prkcsh

protein kinase C substrate 80K-H

chr2_-_119477613 0.224 ENSMUST00000110808.1
ENSMUST00000049920.7
Ino80

INO80 homolog (S. cerevisiae)

chr16_-_17928136 0.183 ENSMUST00000003622.8
Slc25a1
solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1
chr11_+_73199445 0.181 ENSMUST00000006105.6
Shpk
sedoheptulokinase
chr11_+_58199556 0.165 ENSMUST00000058704.8
ENSMUST00000035266.4
ENSMUST00000094169.4
ENSMUST00000168280.1
Irgm2
Igtp


immunity-related GTPase family M member 2
interferon gamma induced GTPase


chr9_-_77347787 0.153 ENSMUST00000184848.1
ENSMUST00000184415.1
Mlip

muscular LMNA-interacting protein

chr15_+_99972780 0.152 ENSMUST00000100206.2
Larp4
La ribonucleoprotein domain family, member 4
chr11_-_86757483 0.151 ENSMUST00000060766.9
ENSMUST00000103186.4
Cltc

clathrin, heavy polypeptide (Hc)

chr15_-_27630644 0.122 ENSMUST00000059662.7
Fam105b
family with sequence similarity 105, member B
chr15_-_100424092 0.121 ENSMUST00000154676.1
Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr11_+_58104229 0.118 ENSMUST00000108843.1
ENSMUST00000134896.1
Cnot8

CCR4-NOT transcription complex, subunit 8

chr10_-_128547722 0.111 ENSMUST00000040572.3
Zc3h10
zinc finger CCCH type containing 10
chr1_+_175632169 0.110 ENSMUST00000097458.3
Kmo
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr11_+_70970181 0.109 ENSMUST00000018593.3
Rpain
RPA interacting protein
chr8_+_117095854 0.106 ENSMUST00000034308.8
ENSMUST00000167370.1
ENSMUST00000176860.1
Bcmo1


beta-carotene 15,15'-monooxygenase


chr7_-_66689474 0.096 ENSMUST00000068980.3
Asb7
ankyrin repeat and SOCS box-containing 7
chr10_+_18845071 0.078 ENSMUST00000019998.7
Perp
PERP, TP53 apoptosis effector
chr11_+_22512088 0.067 ENSMUST00000059319.7
Tmem17
transmembrane protein 17
chr7_+_29983948 0.065 ENSMUST00000148442.1
Zfp568
zinc finger protein 568
chr6_-_83775767 0.062 ENSMUST00000014892.6
Tex261
testis expressed gene 261
chr10_-_119240006 0.048 ENSMUST00000020315.6
Cand1
cullin associated and neddylation disassociated 1
chrX_+_48623737 0.039 ENSMUST00000114936.1
Slc25a14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr11_-_101987004 0.030 ENSMUST00000107173.2
ENSMUST00000107172.1
Dusp3

dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related)

chr11_+_58104138 0.029 ENSMUST00000020822.5
Cnot8
CCR4-NOT transcription complex, subunit 8
chr1_+_135133272 0.017 ENSMUST00000167080.1
Ptpn7
protein tyrosine phosphatase, non-receptor type 7
chr1_-_63176653 0.013 ENSMUST00000027111.8
ENSMUST00000168099.2
Ndufs1

NADH dehydrogenase (ubiquinone) Fe-S protein 1

chr9_-_44417983 0.013 ENSMUST00000053286.7
Ccdc84
coiled-coil domain containing 84

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.6 GO:0097393 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
1.0 3.1 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.9 5.7 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) phosphate ion transmembrane transport(GO:0035435) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.8 6.2 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.6 1.9 GO:0006553 lysine metabolic process(GO:0006553)
0.6 1.8 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.6 4.8 GO:0061368 maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.6 2.8 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.4 1.2 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.4 3.9 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.4 2.3 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.4 2.2 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.4 1.8 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.4 2.5 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.4 1.1 GO:0070973 COPI-coated vesicle budding(GO:0035964) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.3 1.2 GO:0070459 prolactin secretion(GO:0070459)
0.3 1.2 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.3 1.8 GO:0032596 protein transport into membrane raft(GO:0032596) dsRNA transport(GO:0033227)
0.2 1.7 GO:0032264 IMP salvage(GO:0032264)
0.2 1.2 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.2 0.7 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.2 0.7 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.2 1.6 GO:0015862 uridine transport(GO:0015862)
0.2 1.6 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
0.2 1.4 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.2 1.4 GO:0015808 L-alanine transport(GO:0015808)
0.2 2.4 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.2 2.4 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.2 0.7 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.2 0.7 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.2 0.5 GO:0016554 cytidine to uridine editing(GO:0016554)
0.2 0.8 GO:0006543 glutamine catabolic process(GO:0006543)
0.2 0.8 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.1 1.9 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.1 0.4 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.7 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 1.1 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.1 0.4 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.1 0.9 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 1.7 GO:0070932 histone H3 deacetylation(GO:0070932)
0.1 1.2 GO:0097421 liver regeneration(GO:0097421)
0.1 0.8 GO:0015879 carnitine transport(GO:0015879)
0.1 0.3 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.1 2.7 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.1 0.3 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1 8.1 GO:0030279 negative regulation of ossification(GO:0030279)
0.1 0.6 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.1 0.3 GO:0046104 thymidine metabolic process(GO:0046104)
0.1 0.4 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.1 1.1 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.1 0.5 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.1 1.6 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.2 GO:0050915 sensory perception of sour taste(GO:0050915)
0.1 1.7 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.1 0.2 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.1 0.2 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1 0.9 GO:0015858 nucleoside transport(GO:0015858)
0.1 0.6 GO:0030035 microspike assembly(GO:0030035)
0.1 0.4 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1 0.2 GO:0035963 response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.1 0.2 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.1 0.4 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 0.7 GO:0097006 regulation of plasma lipoprotein particle levels(GO:0097006)
0.1 0.3 GO:0042045 epithelial fluid transport(GO:0042045)
0.0 0.8 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 7.7 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 1.2 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.3 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.8 GO:0010039 response to iron ion(GO:0010039)
0.0 5.2 GO:0030518 intracellular steroid hormone receptor signaling pathway(GO:0030518)
0.0 1.8 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0019441 tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) quinolinate biosynthetic process(GO:0019805) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218) kynurenine metabolic process(GO:0070189)
0.0 0.2 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.3 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 1.5 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 4.9 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 1.2 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 0.2 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.5 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 1.3 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.6 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.5 GO:0014741 negative regulation of cardiac muscle hypertrophy(GO:0010614) negative regulation of muscle hypertrophy(GO:0014741)
0.0 1.0 GO:0043113 receptor clustering(GO:0043113)
0.0 0.4 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 0.1 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.1 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0 0.9 GO:0021799 cerebral cortex radially oriented cell migration(GO:0021799)
0.0 0.5 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.1 GO:0002934 desmosome organization(GO:0002934)
0.0 0.2 GO:0006491 N-glycan processing(GO:0006491)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.6 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.7 6.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.4 1.8 GO:1990130 Iml1 complex(GO:1990130)
0.4 2.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.3 3.0 GO:0045298 tubulin complex(GO:0045298)
0.2 1.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.2 1.8 GO:0097427 microtubule bundle(GO:0097427)
0.2 1.2 GO:0070695 FHF complex(GO:0070695)
0.2 0.8 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.5 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.1 0.9 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 10.0 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 2.2 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.1 3.1 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 0.6 GO:0031931 TORC1 complex(GO:0031931)
0.1 2.2 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 0.9 GO:0016460 myosin II complex(GO:0016460)
0.0 0.2 GO:0031523 Myb complex(GO:0031523)
0.0 2.0 GO:0031526 brush border membrane(GO:0031526)
0.0 3.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.6 GO:0005882 intermediate filament(GO:0005882)
0.0 0.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 1.5 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.2 GO:0020003 symbiont-containing vacuole(GO:0020003) extracellular membrane-bounded organelle(GO:0065010)
0.0 1.9 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 4.7 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.3 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.5 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.4 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 1.2 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.1 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
1.9 5.7 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.9 6.6 GO:0015616 DNA translocase activity(GO:0015616)
0.7 4.0 GO:0070699 type II activin receptor binding(GO:0070699)
0.6 2.3 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.5 3.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005) PH domain binding(GO:0042731)
0.5 1.9 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.5 1.4 GO:0015173 hydrogen:amino acid symporter activity(GO:0005280) aromatic amino acid transmembrane transporter activity(GO:0015173)
0.4 3.0 GO:0099609 microtubule lateral binding(GO:0099609)
0.4 1.4 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.3 1.8 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.3 1.4 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.3 9.5 GO:0042805 actinin binding(GO:0042805)
0.3 5.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.3 0.8 GO:0005124 scavenger receptor binding(GO:0005124)
0.2 1.7 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 1.2 GO:0009374 biotin binding(GO:0009374)
0.2 2.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.2 0.7 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.2 0.8 GO:0004359 glutaminase activity(GO:0004359)
0.2 0.8 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.2 0.5 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.2 0.8 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.2 4.8 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 3.2 GO:0071949 FAD binding(GO:0071949)
0.1 1.0 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 0.7 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 0.5 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.7 GO:0016936 galactoside binding(GO:0016936)
0.1 0.9 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 0.3 GO:0046997 sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.1 0.7 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.4 GO:0070573 tripeptidyl-peptidase activity(GO:0008240) metallodipeptidase activity(GO:0070573)
0.1 2.5 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 0.7 GO:0050897 cobalt ion binding(GO:0050897)
0.1 5.9 GO:0017022 myosin binding(GO:0017022)
0.1 0.4 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 1.1 GO:0019104 DNA N-glycosylase activity(GO:0019104)
0.1 0.8 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 1.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 1.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 2.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 1.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 1.2 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 1.2 GO:0008483 transaminase activity(GO:0008483)
0.1 0.4 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 2.3 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 1.6 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.3 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 1.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.2 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.3 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.5 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 1.6 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.1 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 2.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 2.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.5 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.0 1.4 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.3 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.7 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 2.5 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.3 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.4 GO:0005496 steroid binding(GO:0005496)
0.0 0.2 GO:0005248 voltage-gated sodium channel activity(GO:0005248)
0.0 0.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 1.2 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.3 GO:0017137 Rab GTPase binding(GO:0017137)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.3 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.2 2.4 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.2 3.0 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 1.1 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.1 1.2 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 2.7 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.1 6.0 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.1 1.0 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.1 2.2 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.1 3.1 PID_CD8_TCR_PATHWAY TCR signaling in naïve CD8+ T cells
0.1 1.6 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 1.1 PID_ARF_3PATHWAY Arf1 pathway
0.0 0.4 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.7 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.3 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.7 PID_MYC_PATHWAY C-MYC pathway
0.0 0.7 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 0.8 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.8 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 2.1 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.5 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.4 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.2 1.0 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.1 4.0 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.1 3.0 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 6.3 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.7 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.1 1.1 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.1 1.1 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.1 7.0 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.1 0.8 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 1.9 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 2.5 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 1.2 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.5 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.0 0.8 REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 1.4 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.4 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.4 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.2 REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.8 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.2 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.7 REACTOME_INTERFERON_GAMMA_SIGNALING Genes involved in Interferon gamma signaling
0.0 0.1 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.8 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.5 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis