Motif ID: Tfap2b
Z-value: 0.785

Transcription factors associated with Tfap2b:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Tfap2b | ENSMUSG00000025927.7 | Tfap2b |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Tfap2b | mm10_v2_chr1_+_19212054_19212106 | -0.60 | 3.6e-05 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.6 | 4.8 | GO:1902460 | transforming growth factor beta activation(GO:0036363) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462) |
1.1 | 1.1 | GO:0003134 | BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134) |
1.0 | 1.0 | GO:0042660 | positive regulation of cell fate specification(GO:0042660) |
1.0 | 2.9 | GO:0038095 | positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095) |
0.9 | 2.6 | GO:0035880 | embryonic nail plate morphogenesis(GO:0035880) |
0.7 | 4.3 | GO:0003383 | apical constriction(GO:0003383) |
0.6 | 3.9 | GO:1904936 | cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936) |
0.6 | 3.4 | GO:0090005 | negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005) |
0.6 | 5.0 | GO:0098700 | neurotransmitter loading into synaptic vesicle(GO:0098700) |
0.4 | 2.1 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
0.4 | 6.2 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
0.4 | 1.6 | GO:0035470 | positive regulation of vascular wound healing(GO:0035470) |
0.4 | 1.2 | GO:0061153 | trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) |
0.3 | 2.0 | GO:0072513 | positive regulation of secondary heart field cardioblast proliferation(GO:0072513) |
0.3 | 2.0 | GO:0097473 | cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473) |
0.3 | 1.2 | GO:0003430 | growth plate cartilage chondrocyte growth(GO:0003430) |
0.3 | 1.7 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
0.2 | 1.0 | GO:0071475 | cellular hyperosmotic salinity response(GO:0071475) |
0.2 | 0.9 | GO:2000256 | endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163) positive regulation of male germ cell proliferation(GO:2000256) |
0.2 | 0.7 | GO:0038165 | oncostatin-M-mediated signaling pathway(GO:0038165) |
0.2 | 0.4 | GO:0010593 | negative regulation of lamellipodium assembly(GO:0010593) |
0.2 | 1.2 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
0.2 | 0.4 | GO:0021913 | regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) |
0.2 | 1.1 | GO:0070100 | negative regulation of chemokine-mediated signaling pathway(GO:0070100) |
0.2 | 1.9 | GO:0090084 | negative regulation of inclusion body assembly(GO:0090084) |
0.2 | 2.3 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
0.2 | 0.8 | GO:2000255 | negative regulation of male germ cell proliferation(GO:2000255) |
0.1 | 4.0 | GO:1903077 | negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376) |
0.1 | 0.6 | GO:0060857 | establishment of glial blood-brain barrier(GO:0060857) |
0.1 | 1.1 | GO:0060662 | tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662) |
0.1 | 3.3 | GO:0097062 | dendritic spine maintenance(GO:0097062) |
0.1 | 0.7 | GO:0036438 | maintenance of lens transparency(GO:0036438) |
0.1 | 0.5 | GO:0019372 | lipoxygenase pathway(GO:0019372) |
0.1 | 0.3 | GO:1902310 | positive regulation of peptidyl-serine dephosphorylation(GO:1902310) |
0.1 | 0.5 | GO:0010757 | negative regulation of plasminogen activation(GO:0010757) |
0.1 | 0.5 | GO:0010755 | regulation of plasminogen activation(GO:0010755) |
0.1 | 1.4 | GO:0030238 | male sex determination(GO:0030238) |
0.1 | 0.7 | GO:0010694 | positive regulation of alkaline phosphatase activity(GO:0010694) |
0.1 | 1.1 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
0.1 | 0.3 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
0.1 | 1.3 | GO:0097186 | amelogenesis(GO:0097186) |
0.1 | 1.1 | GO:0051256 | mitotic spindle midzone assembly(GO:0051256) |
0.1 | 1.8 | GO:0060033 | anatomical structure regression(GO:0060033) |
0.1 | 2.1 | GO:0040034 | regulation of development, heterochronic(GO:0040034) |
0.1 | 0.9 | GO:0090286 | cytoskeletal anchoring at nuclear membrane(GO:0090286) |
0.1 | 0.7 | GO:2000301 | myeloid progenitor cell differentiation(GO:0002318) negative regulation of synaptic vesicle exocytosis(GO:2000301) |
0.1 | 0.8 | GO:2000394 | positive regulation of lamellipodium morphogenesis(GO:2000394) |
0.1 | 1.1 | GO:0021869 | forebrain ventricular zone progenitor cell division(GO:0021869) |
0.1 | 0.3 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
0.1 | 5.7 | GO:0001676 | long-chain fatty acid metabolic process(GO:0001676) |
0.1 | 0.3 | GO:0090298 | negative regulation of mitochondrial DNA replication(GO:0090298) |
0.1 | 0.4 | GO:2000623 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
0.1 | 0.3 | GO:0046619 | optic placode formation involved in camera-type eye formation(GO:0046619) |
0.1 | 0.2 | GO:1990523 | bone regeneration(GO:1990523) |
0.1 | 0.7 | GO:0070423 | nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431) |
0.1 | 0.4 | GO:0002158 | osteoclast proliferation(GO:0002158) |
0.1 | 0.5 | GO:0045647 | negative regulation of erythrocyte differentiation(GO:0045647) |
0.1 | 0.3 | GO:0030997 | regulation of centriole-centriole cohesion(GO:0030997) |
0.1 | 0.3 | GO:1901165 | positive regulation of trophoblast cell migration(GO:1901165) |
0.1 | 0.7 | GO:0046959 | habituation(GO:0046959) |
0.1 | 0.5 | GO:0006013 | mannose metabolic process(GO:0006013) |
0.1 | 0.2 | GO:0061300 | extracellular matrix-cell signaling(GO:0035426) cerebellum vasculature development(GO:0061300) |
0.1 | 1.0 | GO:0032506 | cytokinetic process(GO:0032506) |
0.1 | 0.2 | GO:0045575 | basophil activation involved in immune response(GO:0002276) basophil activation(GO:0045575) |
0.1 | 1.2 | GO:1902745 | positive regulation of lamellipodium assembly(GO:0010592) megakaryocyte development(GO:0035855) positive regulation of lamellipodium organization(GO:1902745) |
0.0 | 1.7 | GO:0035162 | embryonic hemopoiesis(GO:0035162) |
0.0 | 0.3 | GO:0070127 | tRNA aminoacylation for mitochondrial protein translation(GO:0070127) |
0.0 | 0.4 | GO:2000786 | positive regulation of autophagosome assembly(GO:2000786) |
0.0 | 0.9 | GO:0043486 | histone exchange(GO:0043486) |
0.0 | 0.4 | GO:0033148 | positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148) |
0.0 | 1.5 | GO:0006779 | porphyrin-containing compound biosynthetic process(GO:0006779) |
0.0 | 0.1 | GO:0034372 | very-low-density lipoprotein particle remodeling(GO:0034372) |
0.0 | 0.4 | GO:0043568 | positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568) |
0.0 | 0.1 | GO:0060744 | negative regulation of mammary gland epithelial cell proliferation(GO:0033600) thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744) |
0.0 | 0.2 | GO:0043983 | histone H4-K12 acetylation(GO:0043983) |
0.0 | 0.5 | GO:0001553 | luteinization(GO:0001553) |
0.0 | 0.3 | GO:0007000 | nucleolus organization(GO:0007000) |
0.0 | 0.5 | GO:0045947 | negative regulation of translational initiation(GO:0045947) |
0.0 | 0.4 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
0.0 | 0.4 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
0.0 | 0.4 | GO:0010591 | regulation of lamellipodium assembly(GO:0010591) |
0.0 | 0.4 | GO:0033523 | endodermal cell fate commitment(GO:0001711) histone H2B ubiquitination(GO:0033523) |
0.0 | 0.3 | GO:0048934 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
0.0 | 1.2 | GO:0034605 | cellular response to heat(GO:0034605) |
0.0 | 0.5 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
0.0 | 0.6 | GO:0070207 | protein homotrimerization(GO:0070207) |
0.0 | 0.2 | GO:0046784 | viral mRNA export from host cell nucleus(GO:0046784) |
0.0 | 0.2 | GO:0033564 | anterior/posterior axon guidance(GO:0033564) |
0.0 | 0.3 | GO:0016486 | peptide hormone processing(GO:0016486) |
0.0 | 0.2 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) |
0.0 | 0.3 | GO:0033169 | histone H3-K9 demethylation(GO:0033169) |
0.0 | 0.2 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
0.0 | 0.2 | GO:0051574 | positive regulation of histone H3-K9 methylation(GO:0051574) |
0.0 | 1.8 | GO:0007179 | transforming growth factor beta receptor signaling pathway(GO:0007179) |
0.0 | 0.2 | GO:0008090 | retrograde axonal transport(GO:0008090) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 4.6 | GO:0044316 | cone cell pedicle(GO:0044316) |
0.3 | 1.0 | GO:1990851 | Wnt-Frizzled-LRP5/6 complex(GO:1990851) |
0.2 | 1.0 | GO:0043564 | Ku70:Ku80 complex(GO:0043564) |
0.2 | 0.9 | GO:0008091 | spectrin(GO:0008091) |
0.1 | 0.7 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
0.1 | 2.0 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
0.1 | 2.0 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
0.1 | 0.4 | GO:0002111 | BRCA2-BRAF35 complex(GO:0002111) |
0.1 | 1.0 | GO:0042582 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
0.1 | 1.1 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
0.1 | 0.5 | GO:0097255 | R2TP complex(GO:0097255) |
0.1 | 6.8 | GO:0000118 | histone deacetylase complex(GO:0000118) |
0.1 | 0.9 | GO:0032433 | filopodium tip(GO:0032433) |
0.1 | 0.2 | GO:0031673 | H zone(GO:0031673) |
0.1 | 0.7 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
0.0 | 0.5 | GO:1990023 | mitotic spindle midzone(GO:1990023) |
0.0 | 2.3 | GO:0031901 | early endosome membrane(GO:0031901) |
0.0 | 0.9 | GO:0005581 | collagen trimer(GO:0005581) |
0.0 | 0.4 | GO:0044666 | MLL3/4 complex(GO:0044666) |
0.0 | 0.4 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
0.0 | 0.4 | GO:0031209 | SCAR complex(GO:0031209) |
0.0 | 0.3 | GO:0032797 | SMN complex(GO:0032797) |
0.0 | 0.6 | GO:0008305 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
0.0 | 0.3 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
0.0 | 4.6 | GO:0043296 | apical junction complex(GO:0043296) |
0.0 | 0.4 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
0.0 | 0.2 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
0.0 | 3.0 | GO:0005884 | actin filament(GO:0005884) |
0.0 | 8.0 | GO:0005667 | transcription factor complex(GO:0005667) |
0.0 | 0.8 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
0.0 | 0.3 | GO:0035102 | PRC1 complex(GO:0035102) |
0.0 | 0.2 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
0.0 | 5.1 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
0.0 | 0.3 | GO:0031616 | spindle pole centrosome(GO:0031616) |
0.0 | 0.2 | GO:0061700 | GATOR2 complex(GO:0061700) |
0.0 | 0.5 | GO:0099738 | cell cortex region(GO:0099738) |
0.0 | 0.5 | GO:0031519 | PcG protein complex(GO:0031519) |
0.0 | 0.3 | GO:0000795 | synaptonemal complex(GO:0000795) |
0.0 | 0.7 | GO:0030667 | secretory granule membrane(GO:0030667) |
0.0 | 1.4 | GO:0032993 | protein-DNA complex(GO:0032993) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.7 | 5.0 | GO:0005280 | hydrogen:amino acid symporter activity(GO:0005280) |
0.5 | 1.6 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
0.3 | 1.4 | GO:0045131 | pre-mRNA branch point binding(GO:0045131) |
0.3 | 1.0 | GO:0005110 | frizzled-2 binding(GO:0005110) |
0.3 | 1.2 | GO:0042328 | heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328) |
0.3 | 3.6 | GO:0005522 | profilin binding(GO:0005522) |
0.3 | 1.1 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
0.3 | 6.7 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
0.3 | 1.3 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
0.2 | 0.7 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
0.2 | 0.7 | GO:0016715 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715) |
0.2 | 0.7 | GO:0004923 | leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924) |
0.2 | 3.5 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
0.2 | 0.9 | GO:0008427 | calcium-dependent protein kinase inhibitor activity(GO:0008427) |
0.2 | 1.2 | GO:0008440 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) |
0.2 | 1.1 | GO:0019211 | phosphatase activator activity(GO:0019211) |
0.1 | 1.5 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
0.1 | 2.3 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
0.1 | 1.7 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
0.1 | 1.1 | GO:0048495 | Roundabout binding(GO:0048495) |
0.1 | 0.7 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
0.1 | 0.4 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
0.1 | 0.7 | GO:0043141 | ATP-dependent 5'-3' DNA helicase activity(GO:0043141) |
0.1 | 1.0 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
0.1 | 0.6 | GO:0098634 | protein binding involved in cell-matrix adhesion(GO:0098634) |
0.1 | 1.0 | GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity(GO:0051575) |
0.1 | 2.9 | GO:0001223 | transcription coactivator binding(GO:0001223) |
0.1 | 0.9 | GO:0043495 | protein anchor(GO:0043495) |
0.1 | 0.2 | GO:0034211 | GTP-dependent protein kinase activity(GO:0034211) |
0.1 | 0.4 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
0.1 | 5.7 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.1 | 0.3 | GO:0030621 | U4 snRNA binding(GO:0030621) |
0.1 | 1.2 | GO:0003708 | retinoic acid receptor activity(GO:0003708) |
0.1 | 2.1 | GO:0050699 | WW domain binding(GO:0050699) |
0.1 | 1.5 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
0.1 | 0.3 | GO:0003910 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
0.1 | 0.2 | GO:0035651 | AP-3 adaptor complex binding(GO:0035651) |
0.1 | 0.4 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
0.0 | 0.5 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
0.0 | 1.2 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
0.0 | 0.5 | GO:0015924 | mannosyl-oligosaccharide mannosidase activity(GO:0015924) |
0.0 | 0.4 | GO:0051022 | Rho GDP-dissociation inhibitor binding(GO:0051022) |
0.0 | 0.5 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
0.0 | 0.8 | GO:0051920 | peroxiredoxin activity(GO:0051920) |
0.0 | 0.5 | GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
0.0 | 1.1 | GO:0071837 | HMG box domain binding(GO:0071837) |
0.0 | 0.3 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
0.0 | 0.9 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
0.0 | 2.1 | GO:0035591 | signaling adaptor activity(GO:0035591) |
0.0 | 1.4 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
0.0 | 0.4 | GO:0008432 | JUN kinase binding(GO:0008432) |
0.0 | 0.3 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
0.0 | 0.7 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
0.0 | 0.3 | GO:0050308 | carbohydrate phosphatase activity(GO:0019203) sugar-phosphatase activity(GO:0050308) |
0.0 | 2.0 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
0.0 | 0.2 | GO:0005042 | netrin receptor activity(GO:0005042) |
0.0 | 0.1 | GO:0001517 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) |
0.0 | 2.3 | GO:0002039 | p53 binding(GO:0002039) |
0.0 | 0.1 | GO:0034186 | apolipoprotein A-I binding(GO:0034186) |
0.0 | 0.5 | GO:0030371 | translation repressor activity(GO:0030371) |
0.0 | 0.1 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.0 | 1.5 | GO:0005080 | protein kinase C binding(GO:0005080) |
0.0 | 1.9 | GO:0051082 | unfolded protein binding(GO:0051082) |
0.0 | 0.3 | GO:0008649 | rRNA methyltransferase activity(GO:0008649) |
0.0 | 0.4 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
0.0 | 0.5 | GO:0004180 | carboxypeptidase activity(GO:0004180) |
0.0 | 0.2 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
0.0 | 0.4 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
0.0 | 0.2 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064) |
0.0 | 0.4 | GO:0000400 | four-way junction DNA binding(GO:0000400) |
0.0 | 0.9 | GO:0030145 | manganese ion binding(GO:0030145) |
0.0 | 0.5 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
0.0 | 0.3 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
0.0 | 0.4 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
0.0 | 0.4 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 1.2 | ST_PAC1_RECEPTOR_PATHWAY | PAC1 Receptor Pathway |
0.2 | 6.1 | PID_INSULIN_GLUCOSE_PATHWAY | Insulin-mediated glucose transport |
0.1 | 1.6 | PID_VEGF_VEGFR_PATHWAY | VEGF and VEGFR signaling network |
0.1 | 4.7 | ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY | PI3K Pathway |
0.1 | 10.6 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
0.1 | 2.1 | PID_EPO_PATHWAY | EPO signaling pathway |
0.0 | 1.2 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
0.0 | 1.0 | PID_DNA_PK_PATHWAY | DNA-PK pathway in nonhomologous end joining |
0.0 | 1.6 | NABA_COLLAGENS | Genes encoding collagen proteins |
0.0 | 1.7 | PID_BMP_PATHWAY | BMP receptor signaling |
0.0 | 1.2 | PID_RXR_VDR_PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
0.0 | 0.4 | PID_TCR_RAS_PATHWAY | Ras signaling in the CD4+ TCR pathway |
0.0 | 1.2 | PID_ECADHERIN_NASCENT_AJ_PATHWAY | E-cadherin signaling in the nascent adherens junction |
0.0 | 2.0 | PID_AP1_PATHWAY | AP-1 transcription factor network |
0.0 | 0.2 | SA_REG_CASCADE_OF_CYCLIN_EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
0.0 | 0.6 | PID_ATM_PATHWAY | ATM pathway |
0.0 | 0.5 | PID_MYC_PATHWAY | C-MYC pathway |
0.0 | 1.1 | PID_SMAD2_3NUCLEAR_PATHWAY | Regulation of nuclear SMAD2/3 signaling |
0.0 | 0.2 | SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES | Genes related to the insulin receptor pathway |
0.0 | 0.3 | ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS | Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway. |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 5.0 | REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
0.1 | 2.0 | REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
0.1 | 1.6 | REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
0.1 | 2.8 | REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
0.1 | 0.7 | REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING | Genes involved in Spry regulation of FGF signaling |
0.1 | 4.1 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
0.1 | 1.1 | REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE | Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase |
0.1 | 1.6 | REACTOME_DOUBLE_STRAND_BREAK_REPAIR | Genes involved in Double-Strand Break Repair |
0.1 | 1.3 | REACTOME_REGULATION_OF_KIT_SIGNALING | Genes involved in Regulation of KIT signaling |
0.0 | 0.5 | REACTOME_N_GLYCAN_TRIMMING_IN_THE_ER_AND_CALNEXIN_CALRETICULIN_CYCLE | Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle |
0.0 | 1.2 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
0.0 | 1.6 | REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
0.0 | 0.7 | REACTOME_SIGNALING_BY_BMP | Genes involved in Signaling by BMP |
0.0 | 0.9 | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
0.0 | 0.3 | REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY | Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway |
0.0 | 1.6 | REACTOME_COLLAGEN_FORMATION | Genes involved in Collagen formation |
0.0 | 1.2 | REACTOME_NETRIN1_SIGNALING | Genes involved in Netrin-1 signaling |
0.0 | 4.0 | REACTOME_SIGNALING_BY_RHO_GTPASES | Genes involved in Signaling by Rho GTPases |
0.0 | 0.4 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
0.0 | 0.6 | REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
0.0 | 0.3 | REACTOME_HYALURONAN_METABOLISM | Genes involved in Hyaluronan metabolism |
0.0 | 0.7 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | Genes involved in Ion transport by P-type ATPases |
0.0 | 0.6 | REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
0.0 | 0.3 | REACTOME_NEGATIVE_REGULATION_OF_FGFR_SIGNALING | Genes involved in Negative regulation of FGFR signaling |
0.0 | 0.3 | REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
0.0 | 0.3 | REACTOME_METABOLISM_OF_NON_CODING_RNA | Genes involved in Metabolism of non-coding RNA |
0.0 | 0.9 | REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S | Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S |
0.0 | 0.5 | REACTOME_LYSOSOME_VESICLE_BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
0.0 | 0.2 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
0.0 | 0.2 | REACTOME_ZINC_TRANSPORTERS | Genes involved in Zinc transporters |