Motif ID: Gli3_Zic1

Z-value: 1.129

Transcription factors associated with Gli3_Zic1:

Gene SymbolEntrez IDGene Name
Gli3 ENSMUSG00000021318.9 Gli3
Zic1 ENSMUSG00000032368.8 Zic1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gli3mm10_v2_chr13_+_15463837_15463980-0.654.6e-06Click!
Zic1mm10_v2_chr9_-_91365756_913657740.076.8e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Gli3_Zic1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_101377897 7.463 ENSMUST00000075994.6
Pdzrn3
PDZ domain containing RING finger 3
chr9_+_50752758 5.820 ENSMUST00000034562.7
Cryab
crystallin, alpha B
chr1_-_133801031 4.749 ENSMUST00000143567.1
Atp2b4
ATPase, Ca++ transporting, plasma membrane 4
chr2_-_29253001 4.430 ENSMUST00000071201.4
Ntng2
netrin G2
chr11_-_116654245 4.418 ENSMUST00000021166.5
Cygb
cytoglobin
chr4_+_124657646 4.228 ENSMUST00000053491.7
Pou3f1
POU domain, class 3, transcription factor 1
chr6_+_17463749 4.216 ENSMUST00000115443.1
Met
met proto-oncogene
chrX_-_16911774 4.094 ENSMUST00000040134.7
Ndp
Norrie disease (pseudoglioma) (human)
chr7_+_99268338 4.081 ENSMUST00000107100.2
Map6
microtubule-associated protein 6
chr11_-_42000284 3.999 ENSMUST00000109292.2
ENSMUST00000109290.1
Gabrg2

gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2

chr11_-_42000532 3.790 ENSMUST00000070735.3
Gabrg2
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr8_-_105966038 3.764 ENSMUST00000116429.2
ENSMUST00000034370.9
Slc12a4

solute carrier family 12, member 4

chr16_+_91269759 3.647 ENSMUST00000056882.5
Olig1
oligodendrocyte transcription factor 1
chr17_-_24209377 3.593 ENSMUST00000024931.4
Ntn3
netrin 3
chr4_-_136956784 3.546 ENSMUST00000030420.8
Epha8
Eph receptor A8
chr4_-_148130678 3.460 ENSMUST00000030862.4
Draxin
dorsal inhibitory axon guidance protein
chr4_+_48045144 3.449 ENSMUST00000030025.3
Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr8_+_70501116 3.438 ENSMUST00000127983.1
Crlf1
cytokine receptor-like factor 1
chr4_+_144893077 3.150 ENSMUST00000154208.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr6_-_113531575 3.112 ENSMUST00000032425.5
Emc3
ER membrane protein complex subunit 3
chr14_+_55560480 3.000 ENSMUST00000121622.1
ENSMUST00000143431.1
ENSMUST00000150481.1
Dcaf11


DDB1 and CUL4 associated factor 11


chr8_-_41041828 2.941 ENSMUST00000051379.7
Mtus1
mitochondrial tumor suppressor 1
chr15_-_53902472 2.886 ENSMUST00000078673.6
Samd12
sterile alpha motif domain containing 12
chr7_+_5056856 2.842 ENSMUST00000131368.1
ENSMUST00000123956.1
Ccdc106

coiled-coil domain containing 106

chr1_+_195017399 2.839 ENSMUST00000181273.1
A330023F24Rik
RIKEN cDNA A330023F24 gene
chr8_+_76902277 2.831 ENSMUST00000109912.1
ENSMUST00000128862.1
ENSMUST00000109911.1
Nr3c2


nuclear receptor subfamily 3, group C, member 2


chr4_+_133011506 2.770 ENSMUST00000105915.1
ENSMUST00000105916.1
Ahdc1

AT hook, DNA binding motif, containing 1

chr13_-_117025505 2.763 ENSMUST00000022239.6
Parp8
poly (ADP-ribose) polymerase family, member 8
chr14_-_30353468 2.758 ENSMUST00000112249.1
Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr16_-_91011093 2.651 ENSMUST00000170853.1
ENSMUST00000118390.2
Synj1

synaptojanin 1

chr16_-_91011029 2.578 ENSMUST00000130813.1
Synj1
synaptojanin 1
chr16_+_43503607 2.544 ENSMUST00000126100.1
ENSMUST00000123047.1
ENSMUST00000156981.1
Zbtb20


zinc finger and BTB domain containing 20


chr7_+_99535439 2.541 ENSMUST00000098266.2
ENSMUST00000179755.1
Arrb1

arrestin, beta 1

chr1_-_64121389 2.490 ENSMUST00000055001.3
Klf7
Kruppel-like factor 7 (ubiquitous)
chr13_+_44729535 2.457 ENSMUST00000174068.1
Jarid2
jumonji, AT rich interactive domain 2
chr17_-_68004075 2.444 ENSMUST00000024840.5
Arhgap28
Rho GTPase activating protein 28
chr6_+_86195214 2.440 ENSMUST00000032066.9
Tgfa
transforming growth factor alpha
chr7_-_111779963 2.385 ENSMUST00000049430.8
ENSMUST00000106663.1
Galnt18

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 18

chr11_+_93098404 2.360 ENSMUST00000107859.1
ENSMUST00000042943.6
ENSMUST00000107861.1
ENSMUST00000107858.2
Car10



carbonic anhydrase 10



chr14_+_25607797 2.306 ENSMUST00000160229.1
Zmiz1
zinc finger, MIZ-type containing 1
chr14_+_55560904 2.295 ENSMUST00000072530.4
ENSMUST00000128490.1
Dcaf11

DDB1 and CUL4 associated factor 11

chr7_+_5056706 2.268 ENSMUST00000144802.1
Ccdc106
coiled-coil domain containing 106
chr1_-_56972437 2.243 ENSMUST00000042857.7
Satb2
special AT-rich sequence binding protein 2
chr18_+_22345089 2.227 ENSMUST00000120223.1
ENSMUST00000097655.3
Asxl3

additional sex combs like 3 (Drosophila)

chr12_+_73997749 2.175 ENSMUST00000110451.2
Syt16
synaptotagmin XVI
chr7_+_5057161 2.168 ENSMUST00000045543.5
Ccdc106
coiled-coil domain containing 106
chr6_-_118780324 2.168 ENSMUST00000112793.3
ENSMUST00000075591.6
ENSMUST00000078320.7
ENSMUST00000112790.2
Cacna1c



calcium channel, voltage-dependent, L type, alpha 1C subunit



chr2_-_39190687 2.138 ENSMUST00000142872.1
ENSMUST00000038874.5
Scai

suppressor of cancer cell invasion

chr9_-_56418023 2.134 ENSMUST00000061552.8
C230081A13Rik
RIKEN cDNA C230081A13 gene
chr19_-_4698315 2.122 ENSMUST00000096325.3
Gm960
predicted gene 960
chr1_-_64121456 2.088 ENSMUST00000142009.1
ENSMUST00000114086.1
Klf7

Kruppel-like factor 7 (ubiquitous)

chr6_+_125494419 2.057 ENSMUST00000181266.1
Gm26728
predicted gene, 26728
chr7_+_57591147 2.042 ENSMUST00000039697.7
Gabrb3
gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
chr12_+_109545390 2.014 ENSMUST00000146701.1
Meg3
maternally expressed 3
chrX_+_163908982 2.010 ENSMUST00000069041.8
Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chrX_+_159697308 1.987 ENSMUST00000123433.1
Sh3kbp1
SH3-domain kinase binding protein 1
chr6_+_17463927 1.953 ENSMUST00000115442.1
Met
met proto-oncogene
chr16_+_23107413 1.951 ENSMUST00000023599.6
ENSMUST00000168891.1
Eif4a2

eukaryotic translation initiation factor 4A2

chr11_-_60352869 1.924 ENSMUST00000095254.5
ENSMUST00000102683.4
ENSMUST00000093048.6
ENSMUST00000093046.6
ENSMUST00000064019.8
ENSMUST00000102682.4
Tom1l2





target of myb1-like 2 (chicken)





chr15_-_78718113 1.904 ENSMUST00000088592.4
Elfn2
leucine rich repeat and fibronectin type III, extracellular 2
chr15_-_99820072 1.877 ENSMUST00000109024.2
Lima1
LIM domain and actin binding 1
chr6_-_101377342 1.870 ENSMUST00000151175.1
Pdzrn3
PDZ domain containing RING finger 3
chr7_-_142657466 1.841 ENSMUST00000097936.2
ENSMUST00000000033.5
Igf2

insulin-like growth factor 2

chr11_+_69765970 1.830 ENSMUST00000108642.1
ENSMUST00000156932.1
Zbtb4

zinc finger and BTB domain containing 4

chr2_-_144527341 1.800 ENSMUST00000163701.1
ENSMUST00000081982.5
Dzank1

double zinc ribbon and ankyrin repeat domains 1

chr3_-_104511812 1.780 ENSMUST00000046316.6
Lrig2
leucine-rich repeats and immunoglobulin-like domains 2
chr7_+_130865835 1.756 ENSMUST00000075181.4
ENSMUST00000048180.5
Plekha1

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1

chr15_-_100584075 1.741 ENSMUST00000184908.1
POU6F1
POU domain, class 6, transcription factor 1 (Pou6f1), mRNA
chr15_-_95528228 1.725 ENSMUST00000075275.2
Nell2
NEL-like 2
chr17_+_37050631 1.723 ENSMUST00000172792.1
ENSMUST00000174347.1
Gabbr1

gamma-aminobutyric acid (GABA) B receptor, 1

chr2_-_59948155 1.686 ENSMUST00000153136.1
Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr11_+_69095217 1.649 ENSMUST00000101004.2
Per1
period circadian clock 1
chr14_-_55560340 1.636 ENSMUST00000066106.3
A730061H03Rik
RIKEN cDNA A730061H03 gene
chr10_+_127165118 1.623 ENSMUST00000006914.9
B4galnt1
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr16_-_91011308 1.612 ENSMUST00000121759.1
Synj1
synaptojanin 1
chr11_+_101246405 1.599 ENSMUST00000122006.1
ENSMUST00000151830.1
Ramp2

receptor (calcitonin) activity modifying protein 2

chr1_-_22805994 1.596 ENSMUST00000097808.4
Rims1
regulating synaptic membrane exocytosis 1
chrX_+_74329058 1.580 ENSMUST00000004326.3
Plxna3
plexin A3
chr5_+_143370092 1.569 ENSMUST00000120825.1
Grid2ip
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein 1
chr6_-_125494754 1.555 ENSMUST00000032492.8
Cd9
CD9 antigen
chr16_-_85803106 1.543 ENSMUST00000023610.8
Adamts1
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1
chr14_+_55561060 1.538 ENSMUST00000117701.1
Dcaf11
DDB1 and CUL4 associated factor 11
chrX_-_7574120 1.532 ENSMUST00000045924.7
ENSMUST00000115742.2
ENSMUST00000150787.1
Ppp1r3f


protein phosphatase 1, regulatory (inhibitor) subunit 3F


chr16_-_28445227 1.531 ENSMUST00000100024.1
Fgf12
fibroblast growth factor 12
chr8_+_54954728 1.528 ENSMUST00000033915.7
Gpm6a
glycoprotein m6a
chr17_-_24650270 1.524 ENSMUST00000002572.4
Slc9a3r2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr14_+_84443553 1.520 ENSMUST00000071370.5
Pcdh17
protocadherin 17
chr7_-_84605819 1.519 ENSMUST00000032865.9
Fah
fumarylacetoacetate hydrolase
chr6_-_115251839 1.508 ENSMUST00000032462.6
Timp4
tissue inhibitor of metalloproteinase 4
chrX_+_101299143 1.504 ENSMUST00000118111.1
ENSMUST00000130555.1
ENSMUST00000151528.1
Nlgn3


neuroligin 3


chr13_-_54611274 1.502 ENSMUST00000049575.7
Cltb
clathrin, light polypeptide (Lcb)
chr9_+_100643755 1.498 ENSMUST00000133388.1
Stag1
stromal antigen 1
chr13_-_54611332 1.497 ENSMUST00000091609.4
Cltb
clathrin, light polypeptide (Lcb)
chr9_+_100643448 1.495 ENSMUST00000146312.1
ENSMUST00000129269.1
Stag1

stromal antigen 1

chr7_+_130865756 1.492 ENSMUST00000120441.1
Plekha1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr11_+_73018986 1.486 ENSMUST00000092937.6
Camkk1
calcium/calmodulin-dependent protein kinase kinase 1, alpha
chr18_+_5593566 1.486 ENSMUST00000160910.1
Zeb1
zinc finger E-box binding homeobox 1
chr6_-_28830345 1.486 ENSMUST00000171353.1
Lrrc4
leucine rich repeat containing 4
chr10_+_69534208 1.484 ENSMUST00000182439.1
ENSMUST00000092434.5
ENSMUST00000092432.5
ENSMUST00000092431.5
ENSMUST00000054167.8
ENSMUST00000047061.6
Ank3





ankyrin 3, epithelial





chr11_+_115154139 1.482 ENSMUST00000021076.5
Rab37
RAB37, member of RAS oncogene family
chr9_+_100643605 1.475 ENSMUST00000041418.6
Stag1
stromal antigen 1
chr10_+_69533803 1.455 ENSMUST00000182155.1
ENSMUST00000183169.1
ENSMUST00000183148.1
Ank3


ankyrin 3, epithelial


chr6_+_110645572 1.455 ENSMUST00000071076.6
ENSMUST00000172951.1
Grm7

glutamate receptor, metabotropic 7

chr9_-_108190352 1.448 ENSMUST00000035208.7
Bsn
bassoon
chr5_+_3343893 1.437 ENSMUST00000165117.1
Cdk6
cyclin-dependent kinase 6
chr11_+_87760533 1.430 ENSMUST00000039627.5
ENSMUST00000100644.3
Bzrap1

benzodiazepine receptor associated protein 1

chr6_+_48395652 1.422 ENSMUST00000077093.4
Krba1
KRAB-A domain containing 1
chr18_-_43373248 1.414 ENSMUST00000118043.1
Dpysl3
dihydropyrimidinase-like 3
chr16_+_20733104 1.409 ENSMUST00000115423.1
ENSMUST00000007171.6
Chrd

chordin

chr1_-_134234492 1.395 ENSMUST00000169927.1
Adora1
adenosine A1 receptor
chr2_+_102658640 1.370 ENSMUST00000080210.3
Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr6_+_17463826 1.359 ENSMUST00000140070.1
Met
met proto-oncogene
chr9_-_58158498 1.357 ENSMUST00000168864.2
Islr
immunoglobulin superfamily containing leucine-rich repeat
chr13_+_54949388 1.356 ENSMUST00000026994.7
ENSMUST00000109994.2
Unc5a

unc-5 homolog A (C. elegans)

chr1_-_180483410 1.352 ENSMUST00000136521.1
ENSMUST00000179826.1
6330403A02Rik

RIKEN cDNA 6330403A02 gene

chr4_+_12089373 1.342 ENSMUST00000095143.2
ENSMUST00000063839.5
Rbm12b2

RNA binding motif protein 12 B2

chr13_+_54575008 1.330 ENSMUST00000026988.4
Arl10
ADP-ribosylation factor-like 10
chr2_-_45110241 1.316 ENSMUST00000177302.1
Zeb2
zinc finger E-box binding homeobox 2
chr8_-_85840877 1.304 ENSMUST00000034140.7
Itfg1
integrin alpha FG-GAP repeat containing 1
chr14_+_45351473 1.294 ENSMUST00000111835.2
Styx
serine/threonine/tyrosine interaction protein
chr7_-_19698383 1.289 ENSMUST00000173739.1
Apoe
apolipoprotein E
chr16_-_30550560 1.284 ENSMUST00000140402.1
Tmem44
transmembrane protein 44
chr8_+_11728105 1.277 ENSMUST00000110909.2
ENSMUST00000033908.6
Arhgef7

Rho guanine nucleotide exchange factor (GEF7)

chr8_-_34965631 1.268 ENSMUST00000033929.4
Tnks
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr2_-_155945282 1.264 ENSMUST00000040162.2
Gdf5
growth differentiation factor 5
chr19_+_4711153 1.261 ENSMUST00000008991.6
Sptbn2
spectrin beta, non-erythrocytic 2
chr10_+_40349265 1.239 ENSMUST00000044672.4
ENSMUST00000095743.2
Cdk19

cyclin-dependent kinase 19

chr13_+_54575020 1.238 ENSMUST00000156024.1
Arl10
ADP-ribosylation factor-like 10
chr11_+_101246960 1.230 ENSMUST00000107282.3
Ramp2
receptor (calcitonin) activity modifying protein 2
chr10_+_69533761 1.228 ENSMUST00000182884.1
Ank3
ankyrin 3, epithelial
chr4_+_45848816 1.224 ENSMUST00000107782.1
ENSMUST00000030011.5
1300002K09Rik

RIKEN cDNA 1300002K09 gene

chrX_+_155262443 1.214 ENSMUST00000026324.9
Acot9
acyl-CoA thioesterase 9
chr18_-_38601268 1.212 ENSMUST00000025295.6
Spry4
sprouty homolog 4 (Drosophila)
chr5_+_30588078 1.201 ENSMUST00000066295.2
Kcnk3
potassium channel, subfamily K, member 3
chr11_-_98149551 1.197 ENSMUST00000103143.3
Fbxl20
F-box and leucine-rich repeat protein 20
chr5_-_118244861 1.194 ENSMUST00000117177.1
ENSMUST00000133372.1
ENSMUST00000154786.1
ENSMUST00000121369.1
Rnft2



ring finger protein, transmembrane 2



chr4_+_48585276 1.191 ENSMUST00000123476.1
Tmeff1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr4_-_151108244 1.183 ENSMUST00000131948.1
Camta1
calmodulin binding transcription activator 1
chrX_+_73064787 1.169 ENSMUST00000060418.6
Pnma3
paraneoplastic antigen MA3
chr1_-_134235420 1.155 ENSMUST00000038191.6
ENSMUST00000086465.4
Adora1

adenosine A1 receptor

chr4_+_12140263 1.150 ENSMUST00000050069.2
ENSMUST00000069128.7
Rbm12b1

RNA binding motif protein 12 B1

chrX_+_163909132 1.150 ENSMUST00000033734.7
ENSMUST00000112294.2
Ap1s2

adaptor-related protein complex 1, sigma 2 subunit

chr19_+_5740885 1.150 ENSMUST00000081496.5
Ltbp3
latent transforming growth factor beta binding protein 3
chr8_-_69887687 1.139 ENSMUST00000057831.7
Cilp2
cartilage intermediate layer protein 2
chr18_+_52767994 1.120 ENSMUST00000025413.7
ENSMUST00000163742.2
ENSMUST00000178011.1
Sncaip


synuclein, alpha interacting protein (synphilin)


chr5_+_149411749 1.115 ENSMUST00000093110.5
Medag
mesenteric estrogen dependent adipogenesis
chr4_-_151108454 1.104 ENSMUST00000105670.1
Camta1
calmodulin binding transcription activator 1
chr6_-_85502980 1.102 ENSMUST00000159062.1
Fbxo41
F-box protein 41
chr5_-_32746317 1.099 ENSMUST00000135248.1
Pisd
phosphatidylserine decarboxylase
chr6_+_48395586 1.095 ENSMUST00000114571.1
ENSMUST00000114572.3
ENSMUST00000031815.5
Krba1


KRAB-A domain containing 1


chr4_+_117096049 1.090 ENSMUST00000030443.5
Ptch2
patched homolog 2
chr8_-_105295934 1.088 ENSMUST00000057855.3
Exoc3l
exocyst complex component 3-like
chr2_+_35282380 1.085 ENSMUST00000028239.6
Gsn
gelsolin
chr10_+_39612934 1.081 ENSMUST00000019987.6
Traf3ip2
TRAF3 interacting protein 2
chr1_+_15287259 1.075 ENSMUST00000175681.1
Kcnb2
potassium voltage gated channel, Shab-related subfamily, member 2
chr3_+_28263205 1.072 ENSMUST00000159236.2
Tnik
TRAF2 and NCK interacting kinase
chr8_-_71723308 1.070 ENSMUST00000125092.1
Fcho1
FCH domain only 1
chr1_-_155099630 1.068 ENSMUST00000055322.4
Ier5
immediate early response 5
chr7_+_35119285 1.068 ENSMUST00000042985.9
Cebpa
CCAAT/enhancer binding protein (C/EBP), alpha
chr17_+_37045963 1.065 ENSMUST00000025338.9
Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr6_+_149408973 1.056 ENSMUST00000086829.4
ENSMUST00000111513.2
Bicd1

bicaudal D homolog 1 (Drosophila)

chr6_-_85502858 1.031 ENSMUST00000161546.1
ENSMUST00000161078.1
Fbxo41

F-box protein 41

chr11_-_116359060 1.024 ENSMUST00000149147.1
Rnf157
ring finger protein 157
chr3_-_89245159 1.015 ENSMUST00000090924.6
Trim46
tripartite motif-containing 46
chr2_-_45110336 1.006 ENSMUST00000028229.6
ENSMUST00000152232.1
Zeb2

zinc finger E-box binding homeobox 2

chr7_+_128246812 1.004 ENSMUST00000164710.1
ENSMUST00000070656.5
Tgfb1i1

transforming growth factor beta 1 induced transcript 1

chr5_-_34187670 1.004 ENSMUST00000042701.6
ENSMUST00000119171.1
Mxd4

Max dimerization protein 4

chr19_-_32388462 1.000 ENSMUST00000099514.3
Sgms1
sphingomyelin synthase 1
chrX_+_101299207 0.999 ENSMUST00000065858.2
Nlgn3
neuroligin 3
chr13_+_44729794 0.990 ENSMUST00000172830.1
Jarid2
jumonji, AT rich interactive domain 2
chr7_+_25267669 0.985 ENSMUST00000169266.1
Cic
capicua homolog (Drosophila)
chr6_-_35308110 0.984 ENSMUST00000031868.4
Slc13a4
solute carrier family 13 (sodium/sulfate symporters), member 4
chr17_+_27655572 0.984 ENSMUST00000045896.3
Pacsin1
protein kinase C and casein kinase substrate in neurons 1
chr5_+_71699918 0.980 ENSMUST00000031122.7
Gabrb1
gamma-aminobutyric acid (GABA) A receptor, subunit beta 1
chr5_-_147725988 0.974 ENSMUST00000110529.1
ENSMUST00000031652.3
ENSMUST00000031653.5
Flt1


FMS-like tyrosine kinase 1


chr6_-_41636389 0.968 ENSMUST00000031902.5
Trpv6
transient receptor potential cation channel, subfamily V, member 6
chr5_+_123394782 0.959 ENSMUST00000111596.1
ENSMUST00000068237.5
Mlxip

MLX interacting protein

chr10_+_69534039 0.955 ENSMUST00000182557.1
Ank3
ankyrin 3, epithelial
chr2_+_158667119 0.951 ENSMUST00000045503.4
Ppp1r16b
protein phosphatase 1, regulatory (inhibitor) subunit 16B
chr11_+_85311232 0.949 ENSMUST00000020835.9
Ppm1d
protein phosphatase 1D magnesium-dependent, delta isoform
chr8_+_84415348 0.937 ENSMUST00000121390.1
ENSMUST00000122053.1
Cacna1a

calcium channel, voltage-dependent, P/Q type, alpha 1A subunit

chr4_+_42949814 0.931 ENSMUST00000037872.3
ENSMUST00000098112.2
Dnajb5

DnaJ (Hsp40) homolog, subfamily B, member 5

chr11_-_100939457 0.928 ENSMUST00000138438.1
Stat3
signal transducer and activator of transcription 3
chr6_+_17491216 0.910 ENSMUST00000080469.5
Met
met proto-oncogene
chr3_-_116007399 0.909 ENSMUST00000067485.3
Slc30a7
solute carrier family 30 (zinc transporter), member 7
chr13_+_81783220 0.902 ENSMUST00000022009.8
Cetn3
centrin 3
chr7_+_128246953 0.897 ENSMUST00000167965.1
Tgfb1i1
transforming growth factor beta 1 induced transcript 1
chr2_-_77170592 0.896 ENSMUST00000164114.2
ENSMUST00000049544.7
Ccdc141

coiled-coil domain containing 141

chr7_-_142372210 0.896 ENSMUST00000084412.5
Ifitm10
interferon induced transmembrane protein 10
chr17_+_37045980 0.891 ENSMUST00000174456.1
Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr11_+_70647258 0.872 ENSMUST00000037534.7
Rnf167
ring finger protein 167
chr19_-_6084679 0.855 ENSMUST00000161548.1
Zfpl1
zinc finger like protein 1
chr5_+_26817357 0.849 ENSMUST00000071500.6
Dpp6
dipeptidylpeptidase 6
chr4_-_62208426 0.849 ENSMUST00000068822.3
Zfp37
zinc finger protein 37
chr3_+_105452326 0.839 ENSMUST00000098761.3
Kcnd3
potassium voltage-gated channel, Shal-related family, member 3
chr2_-_160872985 0.835 ENSMUST00000109460.1
ENSMUST00000127201.1
Zhx3

zinc fingers and homeoboxes 3

chrX_-_73966329 0.834 ENSMUST00000114372.2
ENSMUST00000033761.6
Hcfc1

host cell factor C1

chr17_+_56326045 0.831 ENSMUST00000139679.1
ENSMUST00000025036.4
ENSMUST00000086835.5
Kdm4b


lysine (K)-specific demethylase 4B


chr1_-_165460430 0.828 ENSMUST00000027856.7
Dcaf6
DDB1 and CUL4 associated factor 6
chr11_-_118248507 0.821 ENSMUST00000017276.7
Cyth1
cytohesin 1

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 6.8 GO:1904978 regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980)
1.6 4.7 GO:0045763 regulation of arginine metabolic process(GO:0000821) negative regulation of cellular amino acid metabolic process(GO:0045763)
1.3 11.5 GO:0071420 cellular response to histamine(GO:0071420)
1.2 8.4 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
1.1 3.4 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
1.0 4.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
1.0 5.8 GO:0007021 tubulin complex assembly(GO:0007021)
0.9 4.4 GO:0015671 oxygen transport(GO:0015671)
0.9 2.6 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241)
0.8 2.5 GO:2000331 regulation of terminal button organization(GO:2000331)
0.7 2.8 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.6 0.6 GO:1905072 cardiac jelly development(GO:1905072)
0.6 2.4 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.6 2.3 GO:1902724 positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.5 3.3 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.5 3.3 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.5 2.2 GO:0098912 smooth muscle contraction involved in micturition(GO:0060083) membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.5 2.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.5 3.7 GO:0032811 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) negative regulation of epinephrine secretion(GO:0032811)
0.5 0.5 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.5 1.4 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.5 2.8 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.5 5.1 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.4 1.3 GO:0045204 MAPK export from nucleus(GO:0045204)
0.4 1.3 GO:1903002 regulation of lipid transport across blood brain barrier(GO:1903000) positive regulation of lipid transport across blood brain barrier(GO:1903002)
0.4 2.5 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393) follicle-stimulating hormone signaling pathway(GO:0042699)
0.4 1.3 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.4 1.6 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.4 2.3 GO:0030913 paranodal junction assembly(GO:0030913)
0.4 3.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.4 2.3 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.4 1.2 GO:1902460 transforming growth factor beta activation(GO:0036363) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.4 1.5 GO:0006558 L-phenylalanine metabolic process(GO:0006558) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221)
0.4 1.1 GO:1903903 striated muscle atrophy(GO:0014891) positive regulation of keratinocyte apoptotic process(GO:1902174) regulation of establishment of T cell polarity(GO:1903903)
0.4 3.5 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.4 1.1 GO:1900275 negative regulation of phospholipase C activity(GO:1900275)
0.3 1.6 GO:0097167 circadian regulation of translation(GO:0097167)
0.3 2.3 GO:0007296 vitellogenesis(GO:0007296)
0.3 4.2 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.3 2.2 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.3 0.9 GO:0061526 acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) regulation of sulfur amino acid metabolic process(GO:0031335) musculoskeletal movement, spinal reflex action(GO:0050883) acetylcholine secretion(GO:0061526)
0.3 1.5 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.3 2.0 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.3 1.5 GO:0001661 conditioned taste aversion(GO:0001661) negative regulation of glutamate secretion(GO:0014050)
0.3 3.2 GO:0042572 retinol metabolic process(GO:0042572)
0.3 1.7 GO:0099612 protein localization to axon(GO:0099612)
0.3 0.8 GO:0019046 release from viral latency(GO:0019046)
0.3 1.9 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.3 0.8 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.3 0.8 GO:0006533 aspartate catabolic process(GO:0006533) D-amino acid metabolic process(GO:0046416)
0.3 1.6 GO:1902287 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.3 1.0 GO:0009957 epidermal cell fate specification(GO:0009957)
0.3 1.5 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.3 0.8 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.2 3.8 GO:0001553 luteinization(GO:0001553)
0.2 0.7 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.2 2.4 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.2 1.5 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.2 0.7 GO:0070375 ERK5 cascade(GO:0070375)
0.2 1.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.2 1.1 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.2 1.4 GO:0044838 cell quiescence(GO:0044838)
0.2 1.2 GO:0070294 renal sodium ion absorption(GO:0070294)
0.2 0.4 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.2 1.4 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.2 0.6 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.2 3.5 GO:0021516 dorsal spinal cord development(GO:0021516)
0.2 1.0 GO:1903587 negative regulation of peptidyl-serine dephosphorylation(GO:1902309) regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.2 0.7 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.2 1.6 GO:0001574 ganglioside biosynthetic process(GO:0001574) lipid glycosylation(GO:0030259)
0.2 1.6 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.2 2.8 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.2 0.5 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.2 1.4 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.2 1.0 GO:0048597 post-embryonic camera-type eye morphogenesis(GO:0048597)
0.2 2.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.2 1.3 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.2 0.6 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.2 0.5 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.2 0.5 GO:0007521 regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003256) muscle cell fate determination(GO:0007521) mammary placode formation(GO:0060596)
0.1 0.7 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 0.9 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.1 8.0 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 1.4 GO:0015838 proline transport(GO:0015824) amino-acid betaine transport(GO:0015838)
0.1 1.0 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 0.6 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 1.1 GO:0000050 urea cycle(GO:0000050) urea metabolic process(GO:0019627)
0.1 0.4 GO:0070428 granuloma formation(GO:0002432) negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) toll-like receptor 5 signaling pathway(GO:0034146) regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070432) positive regulation of hepatocyte proliferation(GO:2000347)
0.1 0.6 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.5 GO:0043974 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.1 1.5 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.1 1.3 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.1 0.3 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.1 1.0 GO:0036506 maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1 0.5 GO:0090472 dibasic protein processing(GO:0090472)
0.1 1.5 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.1 0.6 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.1 1.1 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.1 0.3 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 1.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 3.6 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.1 0.8 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1 1.0 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.1 1.4 GO:0051601 exocyst localization(GO:0051601)
0.1 1.0 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.4 GO:1903028 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.1 0.4 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.1 0.4 GO:0042866 pyruvate biosynthetic process(GO:0042866) glyoxylate metabolic process(GO:0046487)
0.1 0.5 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 2.1 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 0.4 GO:0046967 cytosol to ER transport(GO:0046967)
0.1 3.6 GO:0007520 myoblast fusion(GO:0007520)
0.1 0.7 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.1 0.8 GO:0097623 potassium ion export across plasma membrane(GO:0097623)
0.1 1.6 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 0.2 GO:0007262 STAT protein import into nucleus(GO:0007262)
0.1 0.3 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.1 0.3 GO:0035864 response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865) axonogenesis involved in innervation(GO:0060385)
0.1 4.9 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.1 0.6 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 1.2 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.1 0.8 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.1 0.9 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 2.0 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.5 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 1.7 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.1 0.2 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.1 0.2 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 1.7 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 0.1 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.1 1.0 GO:0008272 sulfate transport(GO:0008272)
0.1 0.8 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 0.5 GO:0032790 ribosome disassembly(GO:0032790)
0.1 4.1 GO:0032418 lysosome localization(GO:0032418)
0.1 0.3 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 0.7 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.1 0.8 GO:1902170 cellular response to reactive nitrogen species(GO:1902170)
0.1 1.5 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.1 0.4 GO:0048570 notochord morphogenesis(GO:0048570)
0.1 0.3 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.1 0.8 GO:1901898 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 1.4 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.5 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.1 0.3 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 1.5 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 1.1 GO:0001783 B cell apoptotic process(GO:0001783)
0.1 3.4 GO:0030216 keratinocyte differentiation(GO:0030216)
0.1 0.3 GO:0021940 regulation of cerebellar granule cell precursor proliferation(GO:0021936) positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.1 1.3 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.1 2.9 GO:0048663 neuron fate commitment(GO:0048663)
0.0 0.8 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.2 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 1.9 GO:0031529 ruffle organization(GO:0031529)
0.0 0.3 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.0 GO:1903722 regulation of centriole elongation(GO:1903722)
0.0 0.3 GO:0051013 microtubule severing(GO:0051013)
0.0 0.4 GO:0044539 long-chain fatty acid import(GO:0044539)
0.0 0.2 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 0.2 GO:2000398 regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.0 0.7 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.8 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 1.2 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0 0.2 GO:0035902 response to immobilization stress(GO:0035902)
0.0 0.5 GO:0010107 potassium ion import(GO:0010107)
0.0 2.0 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.0 0.3 GO:0002209 behavioral fear response(GO:0001662) behavioral defense response(GO:0002209) fear response(GO:0042596)
0.0 0.1 GO:0060025 regulation of synaptic activity(GO:0060025)
0.0 0.8 GO:0033198 response to ATP(GO:0033198)
0.0 1.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.0 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.0 0.7 GO:0019430 removal of superoxide radicals(GO:0019430)
0.0 1.9 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 1.9 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.0 0.9 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.0 0.4 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.2 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.3 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:1903898 negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.0 0.4 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.5 GO:0035094 response to nicotine(GO:0035094)
0.0 0.9 GO:0048821 erythrocyte development(GO:0048821)
0.0 4.1 GO:0006813 potassium ion transport(GO:0006813)
0.0 1.2 GO:0050729 positive regulation of inflammatory response(GO:0050729)
0.0 1.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.4 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 1.9 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.2 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.2 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.8 GO:0021799 cerebral cortex radially oriented cell migration(GO:0021799)
0.0 0.3 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.3 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 2.7 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.3 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.1 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.0 GO:0072368 regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter(GO:0072368)
0.0 0.7 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.5 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.7 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.4 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.5 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.4 GO:0070266 necroptotic process(GO:0070266)
0.0 1.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 1.5 GO:0001764 neuron migration(GO:0001764)
0.0 0.1 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 1.9 GO:0006457 protein folding(GO:0006457)
0.0 0.2 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 1.5 GO:0006906 vesicle fusion(GO:0006906)
0.0 0.3 GO:0045494 photoreceptor cell maintenance(GO:0045494)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
1.0 5.7 GO:0097512 cardiac myofibril(GO:0097512)
0.8 11.5 GO:1902711 GABA-A receptor complex(GO:1902711)
0.7 3.7 GO:1902710 GABA receptor complex(GO:1902710)
0.6 3.0 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.6 2.8 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.5 4.9 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.4 1.3 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.4 1.7 GO:1990769 proximal neuron projection(GO:1990769)
0.4 1.1 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.3 9.8 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.3 1.6 GO:0008091 spectrin(GO:0008091)
0.3 6.0 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.2 4.7 GO:0097228 sperm principal piece(GO:0097228)
0.2 3.1 GO:0072546 ER membrane protein complex(GO:0072546)
0.2 7.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.2 4.0 GO:0032279 asymmetric synapse(GO:0032279)
0.2 1.3 GO:0000322 storage vacuole(GO:0000322)
0.2 4.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 2.5 GO:0031143 pseudopodium(GO:0031143)
0.2 0.8 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 8.2 GO:0009925 basal plasma membrane(GO:0009925)
0.1 1.0 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 0.6 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 4.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 1.1 GO:0033648 host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.1 0.5 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.2 GO:1990812 growth cone filopodium(GO:1990812)
0.1 0.6 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 8.5 GO:0031594 neuromuscular junction(GO:0031594)
0.1 1.0 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 1.4 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 0.5 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.8 GO:0033270 paranode region of axon(GO:0033270)
0.1 0.5 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 0.6 GO:0072687 meiotic spindle(GO:0072687)
0.1 1.3 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 0.7 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.1 2.4 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 4.2 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 1.4 GO:0030673 axolemma(GO:0030673)
0.1 1.4 GO:0000145 exocyst(GO:0000145)
0.1 0.6 GO:0030478 actin cap(GO:0030478)
0.1 0.7 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 1.7 GO:0030137 COPI-coated vesicle(GO:0030137)
0.1 0.8 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 1.8 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.5 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 1.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 0.4 GO:0042825 TAP complex(GO:0042825)
0.1 0.5 GO:0000812 Swr1 complex(GO:0000812)
0.1 0.8 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 0.8 GO:0036038 MKS complex(GO:0036038)
0.1 0.7 GO:0045180 basal cortex(GO:0045180)
0.0 1.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.6 GO:0045178 basal part of cell(GO:0045178)
0.0 1.6 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 0.8 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 3.3 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.4 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 1.9 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:0097447 dendritic tree(GO:0097447)
0.0 0.9 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.4 GO:0016600 flotillin complex(GO:0016600)
0.0 0.8 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 1.4 GO:0031941 filamentous actin(GO:0031941)
0.0 0.7 GO:0043204 perikaryon(GO:0043204)
0.0 2.4 GO:0030175 filopodium(GO:0030175)
0.0 0.4 GO:0097386 glial cell projection(GO:0097386)
0.0 1.5 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.4 GO:0031011 Ino80 complex(GO:0031011) INO80-type complex(GO:0097346)
0.0 1.0 GO:0032420 stereocilium(GO:0032420)
0.0 0.5 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.8 GO:0030139 endocytic vesicle(GO:0030139)
0.0 3.1 GO:0043197 dendritic spine(GO:0043197)
0.0 0.5 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 3.1 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.5 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 4.1 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 1.5 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.4 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.2 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.6 GO:0030315 T-tubule(GO:0030315)
0.0 1.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 4.2 GO:0016607 nuclear speck(GO:0016607)
0.0 3.3 GO:0005925 focal adhesion(GO:0005925)
0.0 4.3 GO:0016604 nuclear body(GO:0016604)
0.0 0.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.4 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.0 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.0 GO:0055037 recycling endosome(GO:0055037)
0.0 2.3 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.7 GO:0001726 ruffle(GO:0001726)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 8.4 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
1.4 6.8 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
1.1 4.4 GO:0004096 catalase activity(GO:0004096)
0.8 2.5 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.6 11.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.6 4.9 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.6 3.7 GO:0016917 GABA receptor activity(GO:0016917)
0.6 2.8 GO:0097643 amylin receptor activity(GO:0097643)
0.5 3.8 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.5 2.1 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.5 3.4 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.5 1.5 GO:0070905 serine binding(GO:0070905)
0.5 1.4 GO:0098770 FBXO family protein binding(GO:0098770)
0.5 3.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.4 3.5 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.4 1.3 GO:0046911 hydroxyapatite binding(GO:0046848) metal chelating activity(GO:0046911) phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.4 1.7 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.4 1.2 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.4 1.5 GO:2001069 glycogen binding(GO:2001069)
0.4 2.6 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.4 1.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.3 1.0 GO:0005119 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158)
0.3 5.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.3 3.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.3 2.3 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.2 3.0 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.2 1.9 GO:0048495 Roundabout binding(GO:0048495)
0.2 1.4 GO:0045545 syndecan binding(GO:0045545)
0.2 1.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.2 1.4 GO:0005042 netrin receptor activity(GO:0005042)
0.2 1.9 GO:0036122 BMP binding(GO:0036122)
0.2 1.0 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.2 4.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2 0.9 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.2 0.6 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.2 1.4 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.2 1.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 0.8 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250) voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.1 0.6 GO:0004359 glutaminase activity(GO:0004359)
0.1 4.0 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.1 2.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.4 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 1.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.6 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 0.6 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 1.0 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.4 GO:0016880 acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 3.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.8 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.5 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 2.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.4 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.1 1.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 5.5 GO:0032452 histone demethylase activity(GO:0032452)
0.1 3.9 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 0.4 GO:0032052 bile acid binding(GO:0032052)
0.1 1.2 GO:0044548 potassium ion leak channel activity(GO:0022841) S100 protein binding(GO:0044548)
0.1 0.4 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 0.9 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.4 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.1 1.1 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 5.1 GO:0030507 spectrin binding(GO:0030507)
0.1 1.8 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.8 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 0.6 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 3.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 2.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 1.0 GO:0015643 toxic substance binding(GO:0015643)
0.1 1.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 4.0 GO:0030276 clathrin binding(GO:0030276)
0.1 1.4 GO:0045503 dynein light chain binding(GO:0045503)
0.1 0.7 GO:1990715 mRNA CDS binding(GO:1990715)
0.1 2.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.5 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 2.3 GO:0070412 R-SMAD binding(GO:0070412)
0.1 3.2 GO:0070888 E-box binding(GO:0070888)
0.1 1.1 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.1 0.3 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 0.2 GO:0034056 estrogen response element binding(GO:0034056)
0.1 1.5 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 1.2 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 0.8 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 0.3 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.1 0.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 3.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 0.5 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.8 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013)
0.1 1.3 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.5 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 4.3 GO:0005125 cytokine activity(GO:0005125)
0.0 0.5 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.5 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.4 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.8 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 1.0 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 6.8 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.4 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 3.0 GO:0005496 steroid binding(GO:0005496)
0.0 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.4 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 2.2 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 3.1 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.8 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 1.3 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 4.0 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.7 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.3 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 3.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.2 GO:0035064 methylated histone binding(GO:0035064)
0.0 1.1 GO:0017022 myosin binding(GO:0017022)
0.0 1.4 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.5 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.3 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 1.4 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.3 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 4.2 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.7 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.2 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.7 GO:0019894 kinesin binding(GO:0019894)
0.0 6.7 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 1.7 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.6 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 1.0 GO:0004860 protein kinase inhibitor activity(GO:0004860)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 11.2 PID_ARF6_PATHWAY Arf6 signaling events
0.2 2.6 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.2 10.7 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.1 2.3 ST_STAT3_PATHWAY STAT3 Pathway
0.1 5.1 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.1 3.8 PID_PI3KCI_PATHWAY Class I PI3K signaling events
0.1 2.9 PID_ARF_3PATHWAY Arf1 pathway
0.1 3.1 ST_GA12_PATHWAY G alpha 12 Pathway
0.1 3.5 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.1 1.6 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.1 1.0 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.1 2.4 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.1 5.4 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.1 1.9 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 2.2 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.0 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 2.5 PID_TNF_PATHWAY TNF receptor signaling pathway
0.0 1.0 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.0 1.0 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.0 1.6 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 2.2 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 1.5 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 1.5 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.0 1.7 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 3.5 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.7 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 0.5 PID_MYC_PATHWAY C-MYC pathway
0.0 0.5 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.6 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 0.6 PID_ALK1_PATHWAY ALK1 signaling events
0.0 1.0 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.2 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 3.6 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 0.4 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 0.6 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 11.5 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.4 5.1 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2 2.7 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.2 3.2 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.2 7.3 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 2.6 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.2 6.8 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.2 7.1 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.2 1.2 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 1.6 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.2 3.0 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.1 3.0 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 2.5 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 1.3 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.0 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 2.2 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 1.1 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 0.4 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 4.7 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.0 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.1 0.5 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 0.6 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 1.9 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 1.1 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.4 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.6 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.4 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.7 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.0 1.4 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 2.7 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.4 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.6 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 3.4 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.7 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.2 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.3 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 1.0 REACTOME_INWARDLY_RECTIFYING_K_CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.5 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.8 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 1.0 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.9 REACTOME_REGULATION_OF_INSULIN_SECRETION Genes involved in Regulation of Insulin Secretion
0.0 0.4 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.6 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.2 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.7 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME_KERATAN_SULFATE_BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.4 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.4 REACTOME_CA_DEPENDENT_EVENTS Genes involved in Ca-dependent events
0.0 0.7 REACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS Genes involved in Post NMDA receptor activation events
0.0 0.4 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.2 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.3 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.7 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions
0.0 0.6 REACTOME_G_ALPHA_S_SIGNALLING_EVENTS Genes involved in G alpha (s) signalling events