Motif ID: Pou6f2_Pou4f2

Z-value: 0.668

Transcription factors associated with Pou6f2_Pou4f2:

Gene SymbolEntrez IDGene Name
Pou4f2 ENSMUSG00000031688.3 Pou4f2
Pou6f2 ENSMUSG00000009734.11 Pou6f2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou6f2mm10_v2_chr13_-_18382041_18382041-0.508.3e-04Click!
Pou4f2mm10_v2_chr8_-_78436640_784366490.038.7e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Pou6f2_Pou4f2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_-_56296551 7.377 ENSMUST00000021970.9
Cxcl14
chemokine (C-X-C motif) ligand 14
chr5_+_139543889 6.345 ENSMUST00000174792.1
ENSMUST00000031523.8
Uncx

UNC homeobox

chr1_+_153665666 5.176 ENSMUST00000111814.1
ENSMUST00000111810.1
Rgs8

regulator of G-protein signaling 8

chr12_-_112511136 4.980 ENSMUST00000066791.5
Tmem179
transmembrane protein 179
chr1_+_153665274 4.896 ENSMUST00000152114.1
ENSMUST00000111812.1
Rgs8

regulator of G-protein signaling 8

chr4_-_58499398 3.790 ENSMUST00000107570.1
Lpar1
lysophosphatidic acid receptor 1
chr1_+_153665587 3.679 ENSMUST00000147700.1
Rgs8
regulator of G-protein signaling 8
chr1_+_153665627 3.529 ENSMUST00000147482.1
Rgs8
regulator of G-protein signaling 8
chr7_-_49636847 3.467 ENSMUST00000032717.6
Dbx1
developing brain homeobox 1
chr3_+_55782500 2.466 ENSMUST00000075422.4
Mab21l1
mab-21-like 1 (C. elegans)
chr2_-_168767029 2.307 ENSMUST00000075044.3
Sall4
sal-like 4 (Drosophila)
chr12_-_56535047 2.185 ENSMUST00000178477.2
Nkx2-1
NK2 homeobox 1
chr6_-_138426735 2.134 ENSMUST00000162932.1
Lmo3
LIM domain only 3
chr2_-_168767136 1.868 ENSMUST00000029061.5
ENSMUST00000103074.1
Sall4

sal-like 4 (Drosophila)

chr8_-_61902669 1.805 ENSMUST00000121785.1
ENSMUST00000034057.7
Palld

palladin, cytoskeletal associated protein

chr1_-_72874877 1.668 ENSMUST00000027377.8
Igfbp5
insulin-like growth factor binding protein 5
chr10_-_92164666 1.577 ENSMUST00000183123.1
ENSMUST00000182033.1
Rmst

rhabdomyosarcoma 2 associated transcript (non-coding RNA)

chr14_+_27039001 1.540 ENSMUST00000035336.3
Il17rd
interleukin 17 receptor D
chr19_+_24875679 1.522 ENSMUST00000073080.5
Gm10053
predicted gene 10053
chr6_-_138422898 1.519 ENSMUST00000161450.1
ENSMUST00000163024.1
ENSMUST00000162185.1
Lmo3


LIM domain only 3


chr12_+_38781093 1.509 ENSMUST00000161513.1
Etv1
ets variant gene 1
chr6_+_88724828 1.466 ENSMUST00000089449.2
Mgll
monoglyceride lipase
chr4_-_14621669 1.354 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr2_+_71528657 1.333 ENSMUST00000126400.1
Dlx1
distal-less homeobox 1
chrX_+_56447965 1.281 ENSMUST00000079663.6
Gm2174
predicted gene 2174
chr17_+_34592248 1.276 ENSMUST00000038149.6
Pbx2
pre B cell leukemia homeobox 2
chr12_+_38780817 1.255 ENSMUST00000160856.1
Etv1
ets variant gene 1
chr1_+_143777263 1.254 ENSMUST00000018333.6
Uchl5
ubiquitin carboxyl-terminal esterase L5
chr6_+_88724667 1.252 ENSMUST00000163271.1
Mgll
monoglyceride lipase
chr3_-_154328634 1.215 ENSMUST00000167744.1
Lhx8
LIM homeobox protein 8
chr12_+_38780284 1.189 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
Etv1


ets variant gene 1


chr7_-_70366735 1.178 ENSMUST00000089565.5
Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr9_+_53771499 1.147 ENSMUST00000048670.8
Slc35f2
solute carrier family 35, member F2
chr10_+_99263224 1.122 ENSMUST00000020118.4
Dusp6
dual specificity phosphatase 6
chr14_-_69805524 1.030 ENSMUST00000022665.2
Rhobtb2
Rho-related BTB domain containing 2
chrX_-_59166080 1.011 ENSMUST00000119306.1
Fgf13
fibroblast growth factor 13
chr2_+_132847719 0.971 ENSMUST00000124836.1
ENSMUST00000154160.1
Crls1

cardiolipin synthase 1

chr4_+_150237694 0.937 ENSMUST00000141931.1
Eno1
enolase 1, alpha non-neuron
chr4_+_5724304 0.862 ENSMUST00000108380.1
Fam110b
family with sequence similarity 110, member B
chr13_+_99100698 0.819 ENSMUST00000181742.1
Gm807
predicted gene 807
chr4_+_150237211 0.771 ENSMUST00000133839.1
Eno1
enolase 1, alpha non-neuron
chr13_-_102906046 0.768 ENSMUST00000171791.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr4_-_133602168 0.747 ENSMUST00000057311.3
Sfn
stratifin
chr13_-_102905740 0.729 ENSMUST00000167462.1
Mast4
microtubule associated serine/threonine kinase family member 4
chrX_+_114474312 0.725 ENSMUST00000113371.1
ENSMUST00000040504.5
Klhl4

kelch-like 4

chr17_+_17402672 0.684 ENSMUST00000115576.2
Lix1
limb expression 1 homolog (chicken)
chr16_-_59632520 0.670 ENSMUST00000118438.1
Arl6
ADP-ribosylation factor-like 6
chr4_+_117849361 0.665 ENSMUST00000163288.1
Slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr18_-_15063560 0.663 ENSMUST00000168989.1
Kctd1
potassium channel tetramerisation domain containing 1
chr10_-_95673451 0.655 ENSMUST00000099328.1
Anapc15-ps
anaphase prompoting complex C subunit 15, pseudogene
chr1_+_10993452 0.646 ENSMUST00000027056.5
Prex2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr10_-_128549125 0.635 ENSMUST00000177163.1
ENSMUST00000176683.1
ENSMUST00000176010.1
Rpl41


ribosomal protein L41


chr4_+_115088708 0.630 ENSMUST00000171877.1
ENSMUST00000177647.1
ENSMUST00000106548.2
ENSMUST00000030488.2
Pdzk1ip1



PDZK1 interacting protein 1



chr10_-_128549102 0.626 ENSMUST00000176906.1
Rpl41
ribosomal protein L41
chr11_+_60537978 0.601 ENSMUST00000044250.3
Alkbh5
alkB, alkylation repair homolog 5 (E. coli)
chrX_+_9885622 0.596 ENSMUST00000067529.2
ENSMUST00000086165.3
Sytl5

synaptotagmin-like 5

chr4_-_14621494 0.589 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chr17_-_3557713 0.574 ENSMUST00000041003.6
Tfb1m
transcription factor B1, mitochondrial
chr14_-_118052235 0.566 ENSMUST00000022725.2
Dct
dopachrome tautomerase
chr2_+_3114220 0.562 ENSMUST00000072955.5
Fam171a1
family with sequence similarity 171, member A1
chr18_-_88927447 0.552 ENSMUST00000147313.1
Socs6
suppressor of cytokine signaling 6
chr4_-_14621805 0.547 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr1_-_119053619 0.544 ENSMUST00000062483.8
Gli2
GLI-Kruppel family member GLI2
chr7_+_28881656 0.542 ENSMUST00000066880.4
Capn12
calpain 12
chr16_-_42340595 0.539 ENSMUST00000102817.4
Gap43
growth associated protein 43
chr2_-_106002008 0.532 ENSMUST00000155811.1
Dnajc24
DnaJ (Hsp40) homolog, subfamily C, member 24
chr11_-_89538556 0.522 ENSMUST00000169201.1
Ankfn1
ankyrin-repeat and fibronectin type III domain containing 1
chrX_-_53269786 0.519 ENSMUST00000114841.1
ENSMUST00000071023.5
Fam122b

family with sequence similarity 122, member B

chr9_+_15239045 0.497 ENSMUST00000034413.6
Vstm5
V-set and transmembrane domain containing 5
chr1_-_172027269 0.457 ENSMUST00000027837.6
ENSMUST00000111264.1
Vangl2

vang-like 2 (van gogh, Drosophila)

chr10_-_70655934 0.436 ENSMUST00000162144.1
ENSMUST00000162793.1
Phyhipl

phytanoyl-CoA hydroxylase interacting protein-like

chr4_+_117849193 0.429 ENSMUST00000132043.2
ENSMUST00000169990.1
Slc6a9

solute carrier family 6 (neurotransmitter transporter, glycine), member 9

chr2_-_33718789 0.391 ENSMUST00000130532.1
9430024E24Rik
RIKEN cDNA 9430024E24 gene
chr9_-_60649793 0.377 ENSMUST00000053171.7
Lrrc49
leucine rich repeat containing 49
chr7_-_116031047 0.374 ENSMUST00000106612.1
Sox6
SRY-box containing gene 6
chr4_+_150853919 0.369 ENSMUST00000073600.2
Errfi1
ERBB receptor feedback inhibitor 1
chr8_-_92355764 0.352 ENSMUST00000180102.1
ENSMUST00000179421.1
ENSMUST00000179222.1
ENSMUST00000179029.1
4933436C20Rik



RIKEN cDNA 4933436C20 gene



chr18_+_84851338 0.351 ENSMUST00000160180.1
Cyb5
cytochrome b-5
chr6_+_63255971 0.315 ENSMUST00000159561.1
ENSMUST00000095852.3
Grid2

glutamate receptor, ionotropic, delta 2

chrX_+_153237748 0.273 ENSMUST00000112574.2
Klf8
Kruppel-like factor 8
chr6_+_29859374 0.199 ENSMUST00000115238.3
Ahcyl2
S-adenosylhomocysteine hydrolase-like 2
chr13_-_81570640 0.194 ENSMUST00000109565.2
Gpr98
G protein-coupled receptor 98
chr10_+_127420867 0.173 ENSMUST00000064793.6
R3hdm2
R3H domain containing 2
chr15_-_50882806 0.172 ENSMUST00000184885.1
Trps1
trichorhinophalangeal syndrome I (human)
chr3_-_88552859 0.170 ENSMUST00000119002.1
ENSMUST00000029698.8
Lamtor2

late endosomal/lysosomal adaptor, MAPK and MTOR activator 2

chr3_-_130730375 0.166 ENSMUST00000079085.6
Rpl34
ribosomal protein L34
chr2_-_148046896 0.161 ENSMUST00000172928.1
ENSMUST00000047315.3
Foxa2

forkhead box A2

chr7_-_28338719 0.149 ENSMUST00000003527.8
Supt5
suppressor of Ty 5
chr8_+_25720054 0.145 ENSMUST00000068916.8
ENSMUST00000139836.1
Ppapdc1b

phosphatidic acid phosphatase type 2 domain containing 1B

chr4_-_110287479 0.143 ENSMUST00000106598.1
ENSMUST00000102723.4
ENSMUST00000153906.1
Elavl4


ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)


chr3_-_130730310 0.125 ENSMUST00000062601.7
Rpl34
ribosomal protein L34
chr5_+_135106881 0.125 ENSMUST00000005507.3
Mlxipl
MLX interacting protein-like
chr8_-_84662841 0.125 ENSMUST00000060427.4
Ier2
immediate early response 2
chr6_+_77242715 0.124 ENSMUST00000161677.1
Lrrtm1
leucine rich repeat transmembrane neuronal 1
chr12_+_69963452 0.115 ENSMUST00000110560.1
Gm3086
predicted gene 3086
chr3_+_68572245 0.112 ENSMUST00000170788.2
Schip1
schwannomin interacting protein 1
chr17_+_46681038 0.109 ENSMUST00000002845.6
Mea1
male enhanced antigen 1
chrX_+_153237466 0.108 ENSMUST00000143880.1
Klf8
Kruppel-like factor 8
chr6_+_29859686 0.098 ENSMUST00000134438.1
Ahcyl2
S-adenosylhomocysteine hydrolase-like 2
chr6_+_77242644 0.092 ENSMUST00000159616.1
Lrrtm1
leucine rich repeat transmembrane neuronal 1
chr6_+_29859662 0.089 ENSMUST00000128927.2
Ahcyl2
S-adenosylhomocysteine hydrolase-like 2
chr8_-_83458386 0.087 ENSMUST00000081506.3
Scoc
short coiled-coil protein
chr19_-_19001099 0.085 ENSMUST00000040153.8
ENSMUST00000112828.1
Rorb

RAR-related orphan receptor beta

chr8_+_107031218 0.073 ENSMUST00000034388.9
Vps4a
vacuolar protein sorting 4a (yeast)
chr12_-_81532840 0.073 ENSMUST00000166664.1
ENSMUST00000164386.1
ENSMUST00000169158.1
ENSMUST00000164431.1
ENSMUST00000163402.1
Gm20498

Synj2bp


predicted gene 20498

synaptojanin 2 binding protein


chr2_-_148045891 0.071 ENSMUST00000109964.1
Foxa2
forkhead box A2
chrM_+_7005 0.064 ENSMUST00000082405.1
mt-Co2
mitochondrially encoded cytochrome c oxidase II
chr13_-_38635036 0.054 ENSMUST00000035899.6
Bloc1s5
biogenesis of organelles complex-1, subunit 5, muted
chr5_-_120777628 0.040 ENSMUST00000044833.8
Oas3
2'-5' oligoadenylate synthetase 3
chr19_+_41933464 0.039 ENSMUST00000026154.7
Zdhhc16
zinc finger, DHHC domain containing 16
chr2_-_67433181 0.016 ENSMUST00000180773.1
Gm26727
predicted gene, 26727
chr7_+_5080214 0.016 ENSMUST00000098845.3
ENSMUST00000146317.1
ENSMUST00000153169.1
ENSMUST00000045277.6
Epn1



epsin 1



chr2_-_92392634 0.016 ENSMUST00000111279.2
Mapk8ip1
mitogen-activated protein kinase 8 interacting protein 1
chr11_-_101171302 0.004 ENSMUST00000164474.1
ENSMUST00000043397.7
Plekhh3

pleckstrin homology domain containing, family H (with MyTH4 domain) member 3


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.4 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
1.2 17.3 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.9 3.8 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.8 6.3 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.7 2.2 GO:0021759 globus pallidus development(GO:0021759)
0.4 1.3 GO:0061075 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.4 2.7 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.4 1.1 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.4 1.1 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.4 4.0 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.4 2.5 GO:0019532 oxalate transport(GO:0019532)
0.2 1.7 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.2 1.2 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.2 4.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.2 4.0 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.2 0.7 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.2 0.5 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.2 0.6 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.1 1.0 GO:0098909 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.1 2.6 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.4 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.1 1.0 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.1 0.6 GO:0006570 tyrosine metabolic process(GO:0006570)
0.1 0.2 GO:0045014 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594)
0.1 0.5 GO:0050957 equilibrioception(GO:0050957)
0.1 1.3 GO:0048853 forebrain morphogenesis(GO:0048853)
0.1 0.5 GO:0016198 axon choice point recognition(GO:0016198)
0.1 3.7 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 0.4 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 1.3 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.1 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.0 0.1 GO:0009838 abscission(GO:0009838) positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.3 GO:1904861 excitatory synapse assembly(GO:1904861)
0.0 0.6 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.6 GO:0000154 rRNA modification(GO:0000154)
0.0 0.1 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.6 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 1.3 GO:0008585 female gonad development(GO:0008585)
0.0 0.1 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.2 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 17.3 GO:0032809 neuronal cell body membrane(GO:0032809)
0.4 1.7 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.2 1.2 GO:0001674 female germ cell nucleus(GO:0001674)
0.2 1.7 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 2.7 GO:0043196 varicosity(GO:0043196)
0.1 0.5 GO:0060187 cell pole(GO:0060187)
0.1 1.3 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.5 GO:0097542 ciliary tip(GO:0097542)
0.0 1.8 GO:0002102 podosome(GO:0002102)
0.0 3.8 GO:0043198 dendritic shaft(GO:0043198)
0.0 4.2 GO:0000792 heterochromatin(GO:0000792)
0.0 0.6 GO:0070382 exocytic vesicle(GO:0070382)
0.0 0.2 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.5 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.6 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.6 GO:0001772 immunological synapse(GO:0001772)
0.0 1.0 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.6 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.3 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.5 1.5 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.4 17.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 1.7 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.2 7.4 GO:0008009 chemokine activity(GO:0008009)
0.2 2.5 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.2 2.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 1.7 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 2.2 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.2 0.6 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.1 0.6 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 1.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 1.2 GO:0001972 retinoic acid binding(GO:0001972)
0.1 1.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 1.3 GO:0070628 proteasome binding(GO:0070628)
0.1 0.4 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.6 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.7 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.5 GO:0008198 ferrous iron binding(GO:0008198)
0.0 1.0 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 2.5 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.0 20.9 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 0.3 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 0.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0070699 activin receptor binding(GO:0070697) type II activin receptor binding(GO:0070699)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.7 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 3.8 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.0 2.0 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.1 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 6.3 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 2.8 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.5 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.5 PID_FGF_PATHWAY FGF signaling pathway
0.0 1.7 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.5 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 1.3 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.2 PID_TELOMERASE_PATHWAY Regulation of Telomerase

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 20.6 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.1 2.7 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.1 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.7 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.0 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.1 1.1 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.1 1.2 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.7 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.3 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 2.5 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.6 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.0 1.6 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 1.5 REACTOME_SIGNALING_BY_FGFR Genes involved in Signaling by FGFR