Motif ID: Pou3f4

Z-value: 0.526


Transcription factors associated with Pou3f4:

Gene SymbolEntrez IDGene Name
Pou3f4 ENSMUSG00000056854.3 Pou3f4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou3f4mm10_v2_chrX_+_110814390_110814413-0.153.6e-01Click!


Activity profile for motif Pou3f4.

activity profile for motif Pou3f4


Sorted Z-values histogram for motif Pou3f4

Sorted Z-values for motif Pou3f4



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou3f4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_110061319 2.845 ENSMUST00000098110.2
AA474408
expressed sequence AA474408
chr16_-_22439719 2.579 ENSMUST00000079601.6
Etv5
ets variant gene 5
chr19_+_55741810 2.323 ENSMUST00000111657.3
ENSMUST00000061496.9
ENSMUST00000041717.7
ENSMUST00000111662.4
Tcf7l2



transcription factor 7 like 2, T cell specific, HMG box



chr3_+_68869563 2.211 ENSMUST00000054551.2
1110032F04Rik
RIKEN cDNA 1110032F04 gene
chr3_-_57575760 2.019 ENSMUST00000029380.7
Wwtr1
WW domain containing transcription regulator 1
chr3_-_57575907 1.959 ENSMUST00000120977.1
Wwtr1
WW domain containing transcription regulator 1
chr19_+_55742242 1.735 ENSMUST00000111652.1
ENSMUST00000111649.1
ENSMUST00000111651.1
ENSMUST00000111653.1
ENSMUST00000111656.1
ENSMUST00000127233.1
ENSMUST00000153888.1
Tcf7l2






transcription factor 7 like 2, T cell specific, HMG box






chr18_-_74961252 1.735 ENSMUST00000066532.4
Lipg
lipase, endothelial
chr17_-_58991343 1.690 ENSMUST00000025064.7
2610034M16Rik
RIKEN cDNA 2610034M16 gene
chr16_-_22439570 1.642 ENSMUST00000170393.1
Etv5
ets variant gene 5
chr15_-_79285502 1.615 ENSMUST00000165408.1
Baiap2l2
BAI1-associated protein 2-like 2
chr4_+_15881255 1.539 ENSMUST00000029876.1
Calb1
calbindin 1
chr2_+_25180737 1.062 ENSMUST00000104999.2
Nrarp
Notch-regulated ankyrin repeat protein
chr6_-_36811361 1.055 ENSMUST00000101534.1
Ptn
pleiotrophin
chr19_+_55741884 1.004 ENSMUST00000111658.3
ENSMUST00000111654.1
Tcf7l2

transcription factor 7 like 2, T cell specific, HMG box

chr19_+_55742056 0.877 ENSMUST00000111659.2
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr18_+_33794882 0.865 ENSMUST00000146010.2
2410004N09Rik
RIKEN cDNA 2410004N09 gene
chr5_+_137350371 0.862 ENSMUST00000166239.1
ENSMUST00000111054.1
Ephb4

Eph receptor B4

chr19_+_37436707 0.830 ENSMUST00000128184.1
Hhex
hematopoietically expressed homeobox
chr3_+_94933041 0.804 ENSMUST00000090839.5
Selenbp1
selenium binding protein 1
chr5_+_147188678 0.796 ENSMUST00000065382.5
Gsx1
GS homeobox 1
chr4_+_134510999 0.771 ENSMUST00000105866.2
Aunip
aurora kinase A and ninein interacting protein
chr3_+_94693556 0.753 ENSMUST00000090848.3
ENSMUST00000173981.1
ENSMUST00000173849.1
ENSMUST00000174223.1
Selenbp2



selenium binding protein 2



chr3_+_67892189 0.709 ENSMUST00000063263.3
Iqcj
IQ motif containing J
chr18_+_56432116 0.699 ENSMUST00000070166.5
Gramd3
GRAM domain containing 3
chrX_+_106920618 0.683 ENSMUST00000060576.7
Lpar4
lysophosphatidic acid receptor 4
chr8_-_84773381 0.671 ENSMUST00000109764.1
Nfix
nuclear factor I/X
chr3_+_136670076 0.649 ENSMUST00000070198.7
Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr18_+_33794915 0.645 ENSMUST00000179138.1
2410004N09Rik
RIKEN cDNA 2410004N09 gene
chr10_-_39122277 0.638 ENSMUST00000136546.1
Fam229b
family with sequence similarity 229, member B
chr5_-_111761697 0.604 ENSMUST00000129146.1
ENSMUST00000137398.1
ENSMUST00000129065.1
E130006D01Rik


RIKEN cDNA E130006D01 gene


chr18_+_60774510 0.589 ENSMUST00000025511.3
Rps14
ribosomal protein S14
chr13_+_29016267 0.571 ENSMUST00000140415.1
A330102I10Rik
RIKEN cDNA A330102I10 gene
chr6_+_124830217 0.557 ENSMUST00000131847.1
ENSMUST00000151674.1
Cdca3

cell division cycle associated 3

chr2_+_85136355 0.542 ENSMUST00000057019.7
Aplnr
apelin receptor
chr12_+_3572379 0.538 ENSMUST00000173199.1
ENSMUST00000164578.2
ENSMUST00000174479.1
ENSMUST00000173240.1
ENSMUST00000174663.1
ENSMUST00000173736.1
Dtnb





dystrobrevin, beta





chr5_-_137786681 0.536 ENSMUST00000132726.1
Mepce
methylphosphate capping enzyme
chr10_-_128923948 0.533 ENSMUST00000131271.1
Bloc1s1
biogenesis of lysosome-related organelles complex-1, subunit 1
chr18_+_60774675 0.530 ENSMUST00000118551.1
Rps14
ribosomal protein S14
chr3_+_68572245 0.506 ENSMUST00000170788.2
Schip1
schwannomin interacting protein 1
chr2_+_109280738 0.493 ENSMUST00000028527.7
Kif18a
kinesin family member 18A
chr8_+_83997613 0.461 ENSMUST00000095228.3
Samd1
sterile alpha motif domain containing 1
chr10_-_64090241 0.457 ENSMUST00000133588.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr6_-_56704673 0.451 ENSMUST00000170382.2
Lsm5
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr17_+_17316078 0.421 ENSMUST00000105311.3
Gm6712
predicted gene 6712
chr13_+_93304066 0.419 ENSMUST00000109493.1
Homer1
homer homolog 1 (Drosophila)
chr11_-_11890394 0.413 ENSMUST00000109659.2
Ddc
dopa decarboxylase
chr17_-_21908092 0.412 ENSMUST00000106026.2
2210404O09Rik
RIKEN cDNA 2210404O09 gene
chr5_+_28165690 0.408 ENSMUST00000036177.7
En2
engrailed 2
chr4_+_154964117 0.406 ENSMUST00000030931.4
ENSMUST00000070953.4
Pank4

pantothenate kinase 4

chrX_+_150594420 0.398 ENSMUST00000112713.2
Pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr6_+_17463826 0.389 ENSMUST00000140070.1
Met
met proto-oncogene
chr10_+_7667503 0.380 ENSMUST00000040135.8
Nup43
nucleoporin 43
chr3_+_105973711 0.379 ENSMUST00000000573.2
Ovgp1
oviductal glycoprotein 1
chr6_+_17463749 0.376 ENSMUST00000115443.1
Met
met proto-oncogene
chr9_-_55512156 0.376 ENSMUST00000034866.8
Etfa
electron transferring flavoprotein, alpha polypeptide
chr11_-_69795930 0.373 ENSMUST00000045971.8
Chrnb1
cholinergic receptor, nicotinic, beta polypeptide 1 (muscle)
chr3_+_106034661 0.355 ENSMUST00000170669.2
Gm4540
predicted gene 4540
chr3_-_116253467 0.350 ENSMUST00000090473.5
Gpr88
G-protein coupled receptor 88
chr17_-_47016956 0.338 ENSMUST00000165525.1
Gm16494
predicted gene 16494
chr14_-_78088994 0.332 ENSMUST00000118785.2
ENSMUST00000066437.4
Fam216b

family with sequence similarity 216, member B

chr16_+_43508118 0.331 ENSMUST00000114690.1
Zbtb20
zinc finger and BTB domain containing 20
chr11_-_99389351 0.318 ENSMUST00000103131.4
Krt10
keratin 10
chr2_-_176144697 0.305 ENSMUST00000178872.1
Gm2004
predicted gene 2004
chr11_+_93098404 0.289 ENSMUST00000107859.1
ENSMUST00000042943.6
ENSMUST00000107861.1
ENSMUST00000107858.2
Car10



carbonic anhydrase 10



chr2_-_176149825 0.288 ENSMUST00000109049.3
ENSMUST00000179349.1
Gm2004

predicted gene 2004

chr2_-_125859139 0.269 ENSMUST00000110463.1
ENSMUST00000028635.5
Cops2

COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana)

chr18_+_65698253 0.265 ENSMUST00000115097.1
ENSMUST00000117694.1
Oacyl

O-acyltransferase like

chr7_-_126792469 0.261 ENSMUST00000032936.6
Ppp4c
protein phosphatase 4, catalytic subunit
chr10_+_87859062 0.258 ENSMUST00000095360.4
Igf1
insulin-like growth factor 1
chr13_+_49544443 0.247 ENSMUST00000177948.1
ENSMUST00000021820.6
Aspn

asporin

chr15_-_9140374 0.246 ENSMUST00000096482.3
ENSMUST00000110585.2
Skp2

S-phase kinase-associated protein 2 (p45)

chr6_-_12109583 0.242 ENSMUST00000080891.5
Gm6578
predicted gene 6578
chr8_+_62951361 0.240 ENSMUST00000119068.1
Spock3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3
chr9_-_26802563 0.236 ENSMUST00000162252.1
Glb1l2
galactosidase, beta 1-like 2
chr16_+_43247278 0.231 ENSMUST00000114691.1
ENSMUST00000079441.6
Zbtb20

zinc finger and BTB domain containing 20

chr2_-_109280718 0.227 ENSMUST00000147770.1
Mettl15
methyltransferase like 15
chr10_+_90576252 0.227 ENSMUST00000182427.1
ENSMUST00000182053.1
ENSMUST00000182113.1
Anks1b


ankyrin repeat and sterile alpha motif domain containing 1B


chr14_-_47411666 0.224 ENSMUST00000111778.3
Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr2_+_177004553 0.222 ENSMUST00000126358.1
Gm14419
predicted gene 14419
chr15_+_84192223 0.216 ENSMUST00000023071.6
Samm50
sorting and assembly machinery component 50 homolog (S. cerevisiae)
chr11_-_11890368 0.202 ENSMUST00000155690.1
Ddc
dopa decarboxylase
chr2_+_177904285 0.199 ENSMUST00000099001.3
Gm14327
predicted gene 14327
chr17_-_24073479 0.199 ENSMUST00000017090.5
Kctd5
potassium channel tetramerisation domain containing 5
chr5_-_137786651 0.198 ENSMUST00000031740.9
Mepce
methylphosphate capping enzyme
chr2_+_176711933 0.195 ENSMUST00000108983.2
Gm14305
predicted gene 14305
chr5_-_146220901 0.190 ENSMUST00000169407.2
ENSMUST00000161331.1
ENSMUST00000159074.2
ENSMUST00000067837.3
Rnf6



ring finger protein (C3H2C3 type) 6



chr12_-_54695885 0.189 ENSMUST00000067272.8
Eapp
E2F-associated phosphoprotein
chrX_+_96455359 0.189 ENSMUST00000033553.7
Heph
hephaestin
chr2_+_175643978 0.183 ENSMUST00000177700.1
ENSMUST00000178120.1
Gm11007

predicted gene 11007

chr7_+_24507006 0.180 ENSMUST00000176880.1
Zfp428
zinc finger protein 428
chr16_+_14705832 0.179 ENSMUST00000023356.6
Snai2
snail homolog 2 (Drosophila)
chr14_-_18893376 0.177 ENSMUST00000151926.1
Ube2e2
ubiquitin-conjugating enzyme E2E 2
chr13_+_104287855 0.175 ENSMUST00000065766.6
Adamts6
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 6
chr11_+_87578384 0.169 ENSMUST00000107962.1
ENSMUST00000122067.1
Sept4

septin 4

chr2_-_175133322 0.168 ENSMUST00000099029.3
Gm14399
predicted gene 14399
chr18_-_3281036 0.165 ENSMUST00000049942.6
ENSMUST00000139537.1
ENSMUST00000124747.1
Crem


cAMP responsive element modulator


chr2_+_175968942 0.164 ENSMUST00000109008.3
Gm2026
predicted gene 2026
chr10_+_87859255 0.153 ENSMUST00000105300.2
Igf1
insulin-like growth factor 1
chr11_+_93099284 0.153 ENSMUST00000092780.3
ENSMUST00000107863.2
Car10

carbonic anhydrase 10

chr4_+_41569775 0.151 ENSMUST00000102963.3
Dnaic1
dynein, axonemal, intermediate chain 1
chr2_-_30967859 0.142 ENSMUST00000028200.8
Tor1a
torsin family 1, member A (torsin A)
chr5_-_24581879 0.138 ENSMUST00000088299.4
Gm10221
predicted gene 10221
chr12_-_54695829 0.137 ENSMUST00000162106.1
ENSMUST00000160085.1
ENSMUST00000161592.1
ENSMUST00000163433.1
Eapp



E2F-associated phosphoprotein



chr7_+_87803815 0.135 ENSMUST00000125009.1
ENSMUST00000155358.1
Grm5

glutamate receptor, metabotropic 5

chr13_-_92030897 0.130 ENSMUST00000149630.1
Rasgrf2
RAS protein-specific guanine nucleotide-releasing factor 2
chr8_-_86580664 0.128 ENSMUST00000131423.1
ENSMUST00000152438.1
Abcc12

ATP-binding cassette, sub-family C (CFTR/MRP), member 12

chr10_-_127189981 0.127 ENSMUST00000019611.7
Arhgef25
Rho guanine nucleotide exchange factor (GEF) 25
chr6_+_21215472 0.126 ENSMUST00000081542.5
Kcnd2
potassium voltage-gated channel, Shal-related family, member 2
chr2_-_120245157 0.118 ENSMUST00000090071.4
Pla2g4e
phospholipase A2, group IVE
chr8_+_93810832 0.116 ENSMUST00000034198.8
ENSMUST00000125716.1
Gnao1

guanine nucleotide binding protein, alpha O

chr10_-_61979073 0.116 ENSMUST00000105453.1
ENSMUST00000105452.2
ENSMUST00000105454.2
Col13a1


collagen, type XIII, alpha 1


chr14_-_30353468 0.111 ENSMUST00000112249.1
Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr15_-_98831498 0.111 ENSMUST00000168846.1
Prkag1
protein kinase, AMP-activated, gamma 1 non-catalytic subunit
chr4_+_42114817 0.110 ENSMUST00000098123.3
Gm13304
predicted gene 13304
chr2_-_175327598 0.107 ENSMUST00000109050.2
Gm4631
predicted gene 4631
chr1_-_180996145 0.101 ENSMUST00000154133.1
Ephx1
epoxide hydrolase 1, microsomal
chr6_-_102464667 0.093 ENSMUST00000032159.6
Cntn3
contactin 3
chr8_+_80494032 0.088 ENSMUST00000063359.6
Gypa
glycophorin A
chr4_+_41903610 0.077 ENSMUST00000098128.3
Gm21541
predicted gene, 21541
chr4_+_42255767 0.074 ENSMUST00000178864.1
Ccl21b
chemokine (C-C motif) ligand 21B (leucine)
chr11_+_29718563 0.072 ENSMUST00000060992.5
Rtn4
reticulon 4
chrX_-_150814265 0.056 ENSMUST00000026302.6
ENSMUST00000129768.1
ENSMUST00000112699.2
Maged2


melanoma antigen, family D, 2


chr16_+_38562806 0.053 ENSMUST00000171687.1
ENSMUST00000002924.8
Tmem39a

transmembrane protein 39a

chr4_-_117891994 0.048 ENSMUST00000030265.3
Dph2
DPH2 homolog (S. cerevisiae)
chr9_+_14784638 0.047 ENSMUST00000034405.4
Mre11a
meiotic recombination 11 homolog A (S. cerevisiae)
chr10_-_76110956 0.035 ENSMUST00000120757.1
Slc5a4b
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr18_+_37504264 0.034 ENSMUST00000052179.6
Pcdhb20
protocadherin beta 20
chr10_-_64090265 0.030 ENSMUST00000105439.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr7_-_114117761 0.024 ENSMUST00000069449.5
Rras2
related RAS viral (r-ras) oncogene homolog 2
chr9_-_96437434 0.020 ENSMUST00000070500.2
BC043934
cDNA sequence BC043934
chr7_-_90475971 0.019 ENSMUST00000032843.7
Tmem126b
transmembrane protein 126B
chr2_+_125859134 0.017 ENSMUST00000028636.6
ENSMUST00000125084.1
Galk2

galactokinase 2

chr6_+_124304646 0.016 ENSMUST00000112541.2
ENSMUST00000032234.2
Cd163

CD163 antigen

chr6_-_99028874 0.015 ENSMUST00000154163.2
Foxp1
forkhead box P1
chr8_+_62951195 0.012 ENSMUST00000118003.1
Spock3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3
chrX_-_88115632 0.009 ENSMUST00000113966.1
ENSMUST00000113964.1
Il1rapl1

interleukin 1 receptor accessory protein-like 1

chr18_-_36726730 0.003 ENSMUST00000061829.6
Cd14
CD14 antigen

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.2 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.8 1.5 GO:0072235 distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235)
0.7 5.9 GO:0048625 myoblast fate commitment(GO:0048625)
0.6 4.0 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.4 1.7 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.4 1.1 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.2 0.6 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) regulation of connective tissue replacement(GO:1905203)
0.2 0.9 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.2 0.8 GO:0061010 gall bladder development(GO:0061010)
0.2 0.5 GO:0002030 inhibitory G-protein coupled receptor phosphorylation(GO:0002030)
0.1 0.4 GO:1900141 regulation of oligodendrocyte apoptotic process(GO:1900141) negative regulation of oligodendrocyte apoptotic process(GO:1900142)
0.1 0.4 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.8 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.1 0.6 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.1 1.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 0.7 GO:0040031 snRNA modification(GO:0040031)
0.1 1.6 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.8 GO:0021984 adenohypophysis development(GO:0021984)
0.1 0.4 GO:0061743 motor learning(GO:0061743)
0.1 0.2 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.0 0.4 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.2 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 1.1 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.0 0.4 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.2 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.1 GO:0051940 regulation of dopamine uptake involved in synaptic transmission(GO:0051584) regulation of catecholamine uptake involved in synaptic transmission(GO:0051940)
0.0 0.5 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 0.7 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.5 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.4 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.4 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.5 GO:0001553 luteinization(GO:0001553)
0.0 0.3 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.2 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.3 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.5 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.2 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.8 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.2 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.4 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.2 GO:1902916 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148) positive regulation of protein polyubiquitination(GO:1902916)
0.0 0.3 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.2 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.3 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.2 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.0 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.2 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 5.9 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.2 1.6 GO:0071439 clathrin complex(GO:0071439)
0.1 0.4 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.1 0.6 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.4 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 0.4 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.1 0.3 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 0.5 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 0.4 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.5 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.3 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 1.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.2 GO:0097227 sperm annulus(GO:0097227)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.7 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.1 GO:0031594 neuromuscular junction(GO:0031594)
0.0 2.0 GO:0001650 fibrillar center(GO:0001650)
0.0 1.5 GO:0043195 terminal bouton(GO:0043195)
0.0 0.1 GO:0097449 astrocyte projection(GO:0097449)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.3 GO:0005881 cytoplasmic microtubule(GO:0005881)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.4 1.1 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.3 5.9 GO:0070016 gamma-catenin binding(GO:0045295) armadillo repeat domain binding(GO:0070016)
0.2 0.8 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.2 0.6 GO:0036468 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
0.1 1.6 GO:0008430 selenium binding(GO:0008430)
0.1 0.4 GO:0004568 chitinase activity(GO:0004568)
0.1 0.6 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 1.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.7 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.3 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 0.4 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.2 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 0.8 GO:0008301 DNA binding, bending(GO:0008301)
0.1 0.4 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.9 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0001639 PLC activating G-protein coupled glutamate receptor activity(GO:0001639) A2A adenosine receptor binding(GO:0031687) G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.0 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 2.0 GO:0005496 steroid binding(GO:0005496)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 3.9 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.2 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.1 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0 0.7 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 0.1 GO:0004679 AMP-activated protein kinase activity(GO:0004679)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.1 5.9 PID_AP1_PATHWAY AP-1 transcription factor network
0.1 1.1 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 0.7 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 0.9 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 1.2 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.5 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.2 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.0 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 0.1 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.1 0.7 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.1 0.6 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.0 0.4 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.5 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 1.1 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.8 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.5 REACTOME_KINESINS Genes involved in Kinesins
0.0 0.6 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.5 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.4 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis