Motif ID: Tcf7_Tcf7l2

Z-value: 0.986

Transcription factors associated with Tcf7_Tcf7l2:

Gene SymbolEntrez IDGene Name
Tcf7 ENSMUSG00000000782.9 Tcf7
Tcf7l2 ENSMUSG00000024985.12 Tcf7l2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tcf7mm10_v2_chr11_-_52282564_52282579-0.435.2e-03Click!
Tcf7l2mm10_v2_chr19_+_55894508_558945340.288.1e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Tcf7_Tcf7l2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_102706356 4.283 ENSMUST00000123759.1
ENSMUST00000111212.1
ENSMUST00000005220.4
Slc1a2


solute carrier family 1 (glial high affinity glutamate transporter), member 2


chr9_-_96719549 3.362 ENSMUST00000128269.1
Zbtb38
zinc finger and BTB domain containing 38
chr2_+_153031852 3.113 ENSMUST00000037235.6
Xkr7
X Kell blood group precursor related family member 7 homolog
chr10_-_116972609 2.879 ENSMUST00000092165.4
Gm10271
predicted gene 10271
chr2_+_152081529 2.293 ENSMUST00000064061.3
Scrt2
scratch homolog 2, zinc finger protein (Drosophila)
chr12_-_41485751 2.118 ENSMUST00000043884.4
Lrrn3
leucine rich repeat protein 3, neuronal
chr3_+_76074270 1.972 ENSMUST00000038364.8
Fstl5
follistatin-like 5
chr12_+_52699297 1.884 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chr9_-_96719404 1.877 ENSMUST00000140121.1
Zbtb38
zinc finger and BTB domain containing 38
chr16_-_45742888 1.742 ENSMUST00000128348.1
ENSMUST00000066983.6
Abhd10

abhydrolase domain containing 10

chrX_+_101532734 1.616 ENSMUST00000118878.1
ENSMUST00000101341.2
ENSMUST00000149274.1
Taf1


TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor


chr10_-_92165159 1.563 ENSMUST00000182567.1
ENSMUST00000181604.2
ENSMUST00000181213.1
Rmst


rhabdomyosarcoma 2 associated transcript (non-coding RNA)


chr17_+_21690766 1.558 ENSMUST00000097384.1
Gm10509
predicted gene 10509
chr5_+_90759299 1.483 ENSMUST00000031318.4
Cxcl5
chemokine (C-X-C motif) ligand 5
chr4_+_121039385 1.469 ENSMUST00000030372.5
Col9a2
collagen, type IX, alpha 2
chr2_-_38926217 1.381 ENSMUST00000076275.4
ENSMUST00000142130.1
Nr6a1

nuclear receptor subfamily 6, group A, member 1

chr17_+_43952999 1.372 ENSMUST00000177857.1
Rcan2
regulator of calcineurin 2
chr4_-_91376433 1.364 ENSMUST00000107109.2
ENSMUST00000107111.2
ENSMUST00000107120.1
Elavl2


ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)


chr18_+_10725651 1.363 ENSMUST00000165555.1
Mib1
mindbomb homolog 1 (Drosophila)
chr1_-_64121389 1.325 ENSMUST00000055001.3
Klf7
Kruppel-like factor 7 (ubiquitous)
chr1_+_132008285 1.276 ENSMUST00000146432.1
Elk4
ELK4, member of ETS oncogene family
chr13_-_97747399 1.245 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr4_-_91376490 1.244 ENSMUST00000107124.3
Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr6_-_40436104 1.203 ENSMUST00000039008.6
ENSMUST00000101492.3
E330009J07Rik

RIKEN cDNA E330009J07 gene

chr14_+_21750525 1.181 ENSMUST00000022292.3
Samd8
sterile alpha motif domain containing 8
chr17_+_43953191 1.116 ENSMUST00000044792.4
Rcan2
regulator of calcineurin 2
chr10_+_69787431 1.083 ENSMUST00000183240.1
Ank3
ankyrin 3, epithelial
chrX_+_169879596 1.081 ENSMUST00000112105.1
ENSMUST00000078947.5
Mid1

midline 1

chr1_-_105659008 1.079 ENSMUST00000070699.8
Pign
phosphatidylinositol glycan anchor biosynthesis, class N
chr9_-_96752822 1.075 ENSMUST00000152594.1
Zbtb38
zinc finger and BTB domain containing 38
chr13_-_66851513 1.074 ENSMUST00000169322.1
Gm17404
predicted gene, 17404
chr1_+_157458554 1.008 ENSMUST00000046743.4
ENSMUST00000119891.1
BC026585

cDNA sequence BC026585

chr2_-_62483637 0.997 ENSMUST00000136686.1
ENSMUST00000102733.3
Gcg

glucagon

chr17_-_51810866 0.983 ENSMUST00000176669.1
Satb1
special AT-rich sequence binding protein 1
chr6_-_85762480 0.982 ENSMUST00000168531.1
Cml3
camello-like 3
chr1_-_64121456 0.974 ENSMUST00000142009.1
ENSMUST00000114086.1
Klf7

Kruppel-like factor 7 (ubiquitous)

chr7_-_42706369 0.970 ENSMUST00000180131.1
Gm17067
predicted gene 17067
chr15_+_6708372 0.960 ENSMUST00000061656.6
Rictor
RPTOR independent companion of MTOR, complex 2
chr11_-_58904219 0.953 ENSMUST00000102703.1
Zfp39
zinc finger protein 39
chr10_-_92164666 0.939 ENSMUST00000183123.1
ENSMUST00000182033.1
Rmst

rhabdomyosarcoma 2 associated transcript (non-coding RNA)

chr8_+_127447669 0.922 ENSMUST00000159511.1
Pard3
par-3 (partitioning defective 3) homolog (C. elegans)
chr6_+_34384218 0.909 ENSMUST00000038383.7
ENSMUST00000115051.1
Akr1b10

aldo-keto reductase family 1, member B10 (aldose reductase)

chr4_-_119173849 0.890 ENSMUST00000052715.4
ENSMUST00000179290.1
ENSMUST00000154226.1
Zfp691


zinc finger protein 691


chr14_-_45219364 0.884 ENSMUST00000022377.4
ENSMUST00000143609.1
ENSMUST00000139526.1
Txndc16


thioredoxin domain containing 16


chr13_-_66852017 0.865 ENSMUST00000059329.6
Gm17449
predicted gene, 17449
chr6_+_34745952 0.865 ENSMUST00000123823.1
ENSMUST00000136907.1
ENSMUST00000126181.1
Cald1


caldesmon 1


chr5_+_3928033 0.863 ENSMUST00000143365.1
Akap9
A kinase (PRKA) anchor protein (yotiao) 9
chr11_-_62392605 0.845 ENSMUST00000151498.2
ENSMUST00000159069.1
Ncor1

nuclear receptor co-repressor 1

chr10_+_69925484 0.830 ENSMUST00000182692.1
ENSMUST00000092433.5
Ank3

ankyrin 3, epithelial

chr2_+_104065826 0.827 ENSMUST00000104891.1
Gm10912
predicted gene 10912
chrY_+_90755657 0.821 ENSMUST00000167967.2
Gm21857
predicted gene, 21857
chr17_-_78684262 0.809 ENSMUST00000145480.1
Strn
striatin, calmodulin binding protein
chr6_+_117168535 0.805 ENSMUST00000112866.1
ENSMUST00000112871.1
ENSMUST00000073043.4
Cxcl12


chemokine (C-X-C motif) ligand 12


chr14_+_45219993 0.788 ENSMUST00000146150.1
Gpr137c
G protein-coupled receptor 137C
chr2_+_96318014 0.785 ENSMUST00000135431.1
ENSMUST00000162807.2
Lrrc4c

leucine rich repeat containing 4C

chr16_+_10812915 0.779 ENSMUST00000115822.1
Gm11172
predicted gene 11172
chr9_+_95954744 0.779 ENSMUST00000034981.7
Xrn1
5'-3' exoribonuclease 1
chr10_+_69925800 0.753 ENSMUST00000182029.1
Ank3
ankyrin 3, epithelial
chr5_-_138155694 0.753 ENSMUST00000132318.1
ENSMUST00000049393.8
Zfp113

zinc finger protein 113

chr10_+_69925766 0.748 ENSMUST00000182269.1
ENSMUST00000183261.1
ENSMUST00000183074.1
Ank3


ankyrin 3, epithelial


chr2_-_175131864 0.748 ENSMUST00000108929.2
Gm14399
predicted gene 14399
chr5_+_143235143 0.747 ENSMUST00000077485.4
ENSMUST00000032591.8
Zfp12

zinc finger protein 12

chr10_-_61147659 0.742 ENSMUST00000092498.5
ENSMUST00000137833.1
ENSMUST00000155919.1
Sgpl1


sphingosine phosphate lyase 1


chr4_+_148041172 0.739 ENSMUST00000069604.8
Mthfr
5,10-methylenetetrahydrofolate reductase
chr3_-_33143227 0.735 ENSMUST00000108219.1
Pex5l
peroxisomal biogenesis factor 5-like
chr17_+_79614900 0.725 ENSMUST00000040368.2
Rmdn2
regulator of microtubule dynamics 2
chr8_-_111630325 0.723 ENSMUST00000070004.3
Ldhd
lactate dehydrogenase D
chr10_-_127288851 0.723 ENSMUST00000156208.1
ENSMUST00000026476.6
Mbd6

methyl-CpG binding domain protein 6

chr10_+_69925954 0.719 ENSMUST00000181974.1
ENSMUST00000182795.1
ENSMUST00000182437.1
Ank3


ankyrin 3, epithelial


chr4_+_95967322 0.711 ENSMUST00000107083.1
Hook1
hook homolog 1 (Drosophila)
chr8_+_40354303 0.711 ENSMUST00000136835.1
Micu3
mitochondrial calcium uptake family, member 3
chr13_+_94083490 0.705 ENSMUST00000156071.1
Lhfpl2
lipoma HMGIC fusion partner-like 2
chr17_+_46202740 0.698 ENSMUST00000087031.5
Xpo5
exportin 5
chr15_-_98871175 0.696 ENSMUST00000178486.2
ENSMUST00000023741.9
Kmt2d

lysine (K)-specific methyltransferase 2D

chr3_-_19264959 0.695 ENSMUST00000121951.1
Pde7a
phosphodiesterase 7A
chr18_+_10725530 0.693 ENSMUST00000052838.4
Mib1
mindbomb homolog 1 (Drosophila)
chr7_-_28008416 0.678 ENSMUST00000180024.1
Zfp850
zinc finger protein 850
chr9_-_123862023 0.665 ENSMUST00000182350.1
ENSMUST00000078755.2
Xcr1

chemokine (C motif) receptor 1

chr6_-_41636389 0.662 ENSMUST00000031902.5
Trpv6
transient receptor potential cation channel, subfamily V, member 6
chr9_-_71896047 0.656 ENSMUST00000184448.1
Tcf12
transcription factor 12
chr4_+_108479081 0.654 ENSMUST00000155068.1
Zcchc11
zinc finger, CCHC domain containing 11
chr16_+_87698904 0.650 ENSMUST00000026703.5
Bach1
BTB and CNC homology 1
chr16_-_44139630 0.649 ENSMUST00000137557.1
ENSMUST00000147025.1
Atp6v1a

ATPase, H+ transporting, lysosomal V1 subunit A

chr10_+_18407658 0.646 ENSMUST00000037341.7
Nhsl1
NHS-like 1
chr11_+_108921648 0.625 ENSMUST00000144511.1
Axin2
axin2
chr10_+_67096456 0.623 ENSMUST00000174317.1
Jmjd1c
jumonji domain containing 1C
chr1_+_110099295 0.619 ENSMUST00000134301.1
Cdh7
cadherin 7, type 2
chr3_-_116712696 0.618 ENSMUST00000169530.1
Slc35a3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr18_-_62756275 0.618 ENSMUST00000067450.1
ENSMUST00000048109.5
2700046A07Rik

RIKEN cDNA 2700046A07 gene

chr1_+_165788746 0.617 ENSMUST00000161559.2
Cd247
CD247 antigen
chr7_+_27499315 0.606 ENSMUST00000098644.2
ENSMUST00000108355.1
Prx

periaxin

chr17_-_55712571 0.601 ENSMUST00000086876.5
Pot1b
protection of telomeres 1B
chr6_-_148831395 0.597 ENSMUST00000145960.1
Ipo8
importin 8
chr8_+_84415348 0.595 ENSMUST00000121390.1
ENSMUST00000122053.1
Cacna1a

calcium channel, voltage-dependent, P/Q type, alpha 1A subunit

chr5_+_17574268 0.593 ENSMUST00000030568.7
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr13_-_97747373 0.593 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr1_+_191906743 0.584 ENSMUST00000044954.6
Slc30a1
solute carrier family 30 (zinc transporter), member 1
chr1_+_128244122 0.581 ENSMUST00000027592.3
Ubxn4
UBX domain protein 4
chrX_+_159459125 0.571 ENSMUST00000043151.5
ENSMUST00000112470.1
ENSMUST00000156172.1
Map7d2


MAP7 domain containing 2


chr14_+_25607797 0.570 ENSMUST00000160229.1
Zmiz1
zinc finger, MIZ-type containing 1
chr7_+_39449479 0.570 ENSMUST00000061201.8
Zfp939
zinc finger protein 939
chr3_+_137671524 0.564 ENSMUST00000166899.2
Gm21962
predicted gene, 21962
chr1_+_109993982 0.553 ENSMUST00000027542.6
Cdh7
cadherin 7, type 2
chr1_+_37219191 0.551 ENSMUST00000027288.7
Cnga3
cyclic nucleotide gated channel alpha 3
chr11_+_87109221 0.551 ENSMUST00000020794.5
Ska2
spindle and kinetochore associated complex subunit 2
chr14_-_70323783 0.551 ENSMUST00000151011.1
Slc39a14
solute carrier family 39 (zinc transporter), member 14
chr15_+_79891631 0.542 ENSMUST00000177350.1
ENSMUST00000177483.1
Apobec3

apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3

chr2_+_61804453 0.541 ENSMUST00000048934.8
Tbr1
T-box brain gene 1
chr7_-_99828344 0.537 ENSMUST00000036331.6
Neu3
neuraminidase 3
chr1_-_133906973 0.520 ENSMUST00000126123.1
Optc
opticin
chr7_-_101845300 0.502 ENSMUST00000094141.5
Folr2
folate receptor 2 (fetal)
chr1_+_165788681 0.491 ENSMUST00000161971.1
ENSMUST00000178336.1
ENSMUST00000005907.5
ENSMUST00000027849.4
Cd247



CD247 antigen



chr7_+_132859225 0.490 ENSMUST00000084497.5
ENSMUST00000181577.1
ENSMUST00000106161.1
Fam175b


family with sequence similarity 175, member B


chr15_-_103215285 0.482 ENSMUST00000122182.1
ENSMUST00000108813.3
ENSMUST00000127191.1
Cbx5


chromobox 5


chr5_+_138085083 0.480 ENSMUST00000019660.4
ENSMUST00000066617.5
ENSMUST00000110963.1
Zkscan1


zinc finger with KRAB and SCAN domains 1


chr11_-_95699143 0.480 ENSMUST00000062249.2
Gm9796
predicted gene 9796
chr6_-_122340499 0.478 ENSMUST00000160843.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr17_-_47924460 0.477 ENSMUST00000113262.1
Foxp4
forkhead box P4
chr5_-_62765618 0.477 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr3_+_124321031 0.477 ENSMUST00000058994.4
Tram1l1
translocation associated membrane protein 1-like 1
chr17_-_47924400 0.476 ENSMUST00000113263.1
ENSMUST00000097311.2
Foxp4

forkhead box P4

chr17_+_16972910 0.475 ENSMUST00000071374.5
BC002059
cDNA sequence BC002059
chr10_-_30618436 0.471 ENSMUST00000161074.1
Hint3
histidine triad nucleotide binding protein 3
chr1_-_172082757 0.470 ENSMUST00000003550.4
Ncstn
nicastrin
chr1_+_60181495 0.469 ENSMUST00000160834.1
Nbeal1
neurobeachin like 1
chr10_+_89744988 0.461 ENSMUST00000020112.5
Uhrf1bp1l
UHRF1 (ICBP90) binding protein 1-like
chr6_-_122340200 0.456 ENSMUST00000159384.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr17_-_46202576 0.450 ENSMUST00000024749.7
Polh
polymerase (DNA directed), eta (RAD 30 related)
chr6_+_3993776 0.450 ENSMUST00000031673.5
Gngt1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr13_-_73678005 0.446 ENSMUST00000022105.7
ENSMUST00000109680.2
ENSMUST00000109679.2
Slc6a18


solute carrier family 6 (neurotransmitter transporter), member 18


chr11_-_103938211 0.445 ENSMUST00000133774.2
ENSMUST00000149642.1
Nsf

N-ethylmaleimide sensitive fusion protein

chr12_-_86726439 0.444 ENSMUST00000021682.8
Angel1
angel homolog 1 (Drosophila)
chr10_-_115587739 0.442 ENSMUST00000020350.8
Lgr5
leucine rich repeat containing G protein coupled receptor 5
chr2_+_136052180 0.441 ENSMUST00000144403.1
Lamp5
lysosomal-associated membrane protein family, member 5
chr17_-_32886083 0.440 ENSMUST00000178401.1
Zfp870
zinc finger protein 870
chr9_-_43116514 0.439 ENSMUST00000061833.4
Tmem136
transmembrane protein 136
chr10_-_30618337 0.438 ENSMUST00000019925.5
Hint3
histidine triad nucleotide binding protein 3
chr17_+_45555693 0.436 ENSMUST00000024742.7
Nfkbie
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon
chr5_-_63650264 0.435 ENSMUST00000067917.3
Gm9954
predicted gene 9954
chr3_-_73056943 0.434 ENSMUST00000059407.7
Slitrk3
SLIT and NTRK-like family, member 3
chr10_+_52358767 0.432 ENSMUST00000180473.1
Gm26741
predicted gene, 26741
chr11_-_70220794 0.431 ENSMUST00000159867.1
Slc16a13
solute carrier family 16 (monocarboxylic acid transporters), member 13
chr15_+_102407144 0.431 ENSMUST00000169619.1
Sp1
trans-acting transcription factor 1
chr2_-_151973387 0.428 ENSMUST00000109863.1
Fam110a
family with sequence similarity 110, member A
chr2_+_35582829 0.427 ENSMUST00000135741.1
Dab2ip
disabled 2 interacting protein
chr15_-_66500857 0.427 ENSMUST00000023006.6
Lrrc6
leucine rich repeat containing 6 (testis)
chr2_-_172043466 0.426 ENSMUST00000087950.3
Cbln4
cerebellin 4 precursor protein
chr9_+_21927471 0.421 ENSMUST00000170304.1
ENSMUST00000006403.6
Ccdc159

coiled-coil domain containing 159

chrX_+_166238923 0.420 ENSMUST00000060210.7
ENSMUST00000112233.1
Gpm6b

glycoprotein m6b

chr10_+_127725392 0.419 ENSMUST00000026466.3
Tac2
tachykinin 2
chr8_-_8639363 0.418 ENSMUST00000152698.1
Efnb2
ephrin B2
chr10_-_127288999 0.411 ENSMUST00000119078.1
Mbd6
methyl-CpG binding domain protein 6
chr7_-_42578588 0.408 ENSMUST00000179470.1
Gm21028
predicted gene, 21028
chr18_-_61211572 0.408 ENSMUST00000146409.1
Slc26a2
solute carrier family 26 (sulfate transporter), member 2
chr15_-_50890396 0.408 ENSMUST00000185183.1
Trps1
trichorhinophalangeal syndrome I (human)
chr11_-_84067063 0.407 ENSMUST00000108101.1
Dusp14
dual specificity phosphatase 14
chr3_+_86084434 0.406 ENSMUST00000107664.2
Sh3d19
SH3 domain protein D19
chr1_+_109983737 0.406 ENSMUST00000172005.1
Cdh7
cadherin 7, type 2
chr4_+_136206365 0.406 ENSMUST00000047526.7
Asap3
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr16_+_62814676 0.397 ENSMUST00000055557.5
Stx19
syntaxin 19
chr1_-_163725123 0.393 ENSMUST00000159679.1
Mettl11b
methyltransferase like 11B
chr1_-_59237093 0.379 ENSMUST00000163058.1
ENSMUST00000027178.6
Als2

amyotrophic lateral sclerosis 2 (juvenile)

chr10_-_26078987 0.377 ENSMUST00000066049.6
Tmem200a
transmembrane protein 200A
chr7_+_38183787 0.372 ENSMUST00000067854.8
ENSMUST00000177983.1
1600014C10Rik

RIKEN cDNA 1600014C10 gene

chr14_+_73661225 0.370 ENSMUST00000098874.3
Gm21750
predicted gene, 21750
chr7_-_80324115 0.369 ENSMUST00000123189.1
Rccd1
RCC1 domain containing 1
chr12_+_116275386 0.366 ENSMUST00000090195.4
Gm11027
predicted gene 11027
chr11_-_88718165 0.366 ENSMUST00000107908.1
Msi2
musashi RNA-binding protein 2
chr5_+_14025305 0.363 ENSMUST00000073957.6
Sema3e
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chrX_+_113298231 0.362 ENSMUST00000113382.1
ENSMUST00000067219.4
Dach2

dachshund 2 (Drosophila)

chr3_+_55461758 0.359 ENSMUST00000070418.4
Dclk1
doublecortin-like kinase 1
chr16_+_82828382 0.358 ENSMUST00000177665.1
Gm21833
predicted gene, 21833
chr1_+_170644523 0.358 ENSMUST00000046792.8
Olfml2b
olfactomedin-like 2B
chr17_+_35077080 0.352 ENSMUST00000172959.1
Ly6g6e
lymphocyte antigen 6 complex, locus G6E
chr1_+_172126750 0.349 ENSMUST00000075895.2
ENSMUST00000111252.3
Pex19

peroxisomal biogenesis factor 19

chr9_-_42457594 0.348 ENSMUST00000125995.1
Tbcel
tubulin folding cofactor E-like
chr7_+_120677579 0.347 ENSMUST00000060175.6
BC030336
cDNA sequence BC030336
chr10_+_19356558 0.346 ENSMUST00000053225.5
Olig3
oligodendrocyte transcription factor 3
chr5_+_137630116 0.346 ENSMUST00000175968.1
Lrch4
leucine-rich repeats and calponin homology (CH) domain containing 4
chrX_+_166238901 0.344 ENSMUST00000112235.1
Gpm6b
glycoprotein m6b
chr9_-_64341145 0.341 ENSMUST00000120760.1
ENSMUST00000168844.2
Dis3l

DIS3 mitotic control homolog (S. cerevisiae)-like

chr3_+_55242526 0.341 ENSMUST00000054237.7
ENSMUST00000167204.1
Dclk1

doublecortin-like kinase 1

chr9_+_100597686 0.338 ENSMUST00000124487.1
Stag1
stromal antigen 1
chr10_-_82622926 0.334 ENSMUST00000176200.1
ENSMUST00000183416.1
1190007I07Rik

RIKEN cDNA 1190007I07 gene

chr5_+_69556924 0.333 ENSMUST00000087228.4
ENSMUST00000031113.6
Guf1

GUF1 GTPase homolog (S. cerevisiae)

chr6_-_47813512 0.332 ENSMUST00000077290.7
Pdia4
protein disulfide isomerase associated 4
chr2_-_110362985 0.326 ENSMUST00000099626.3
Fibin
fin bud initiation factor homolog (zebrafish)
chr2_+_125866107 0.326 ENSMUST00000134337.1
ENSMUST00000094604.2
ENSMUST00000134798.1
Galk2


galactokinase 2


chr2_+_29890534 0.322 ENSMUST00000113764.3
Odf2
outer dense fiber of sperm tails 2
chr9_+_77921908 0.321 ENSMUST00000133757.1
Elovl5
ELOVL family member 5, elongation of long chain fatty acids (yeast)
chr10_+_80148263 0.317 ENSMUST00000099492.3
ENSMUST00000042057.5
Midn

midnolin

chr11_-_70220776 0.315 ENSMUST00000141290.1
Slc16a13
solute carrier family 16 (monocarboxylic acid transporters), member 13
chr3_-_19265007 0.314 ENSMUST00000091314.4
Pde7a
phosphodiesterase 7A
chr3_-_82876483 0.311 ENSMUST00000048647.7
Rbm46
RNA binding motif protein 46
chr1_+_88227005 0.311 ENSMUST00000061013.6
ENSMUST00000113130.1
Mroh2a

maestro heat-like repeat family member 2A

chr7_-_105787567 0.309 ENSMUST00000144189.1
Dchs1
dachsous 1 (Drosophila)
chr2_-_150255591 0.308 ENSMUST00000063463.5
Gm21994
predicted gene 21994
chr9_+_78051938 0.304 ENSMUST00000024104.7
Gcm1
glial cells missing homolog 1 (Drosophila)
chr3_-_20035285 0.303 ENSMUST00000108321.1
ENSMUST00000012580.6
Hps3

Hermansky-Pudlak syndrome 3 homolog (human)

chr4_+_99194124 0.303 ENSMUST00000180278.1
Atg4c
autophagy related 4C, cysteine peptidase

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.3 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.6 1.7 GO:0019389 glucuronoside metabolic process(GO:0019389)
0.5 1.5 GO:0070944 neutrophil mediated killing of bacterium(GO:0070944)
0.5 1.9 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.4 4.1 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.3 1.6 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.2 0.4 GO:0042940 D-amino acid transport(GO:0042940)
0.2 0.8 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.2 0.6 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.2 0.6 GO:0050883 regulation of sulfur amino acid metabolic process(GO:0031335) musculoskeletal movement, spinal reflex action(GO:0050883)
0.2 0.6 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.2 0.6 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.2 0.6 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.2 0.7 GO:0070829 heterochromatin maintenance(GO:0070829)
0.2 0.7 GO:1900368 regulation of RNA interference(GO:1900368)
0.2 0.9 GO:0003383 apical constriction(GO:0003383)
0.1 1.2 GO:2000303 regulation of ceramide biosynthetic process(GO:2000303)
0.1 0.6 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.1 1.0 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.1 2.5 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.1 1.0 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 0.7 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 0.6 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.1 1.1 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.5 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1 0.3 GO:1903334 positive regulation of protein folding(GO:1903334)
0.1 0.8 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.5 GO:0001661 conditioned taste aversion(GO:0001661) amygdala development(GO:0021764)
0.1 0.5 GO:0006689 ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.1 0.7 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1 0.4 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 0.3 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
0.1 1.0 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.6 GO:0060666 pulmonary myocardium development(GO:0003350) dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.7 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 0.3 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.1 0.3 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 1.3 GO:0070932 histone H3 deacetylation(GO:0070932)
0.1 0.3 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.5 GO:0032196 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) transposition(GO:0032196)
0.1 0.6 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 0.4 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.1 0.4 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1 0.6 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.1 0.3 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.1 1.0 GO:1901250 regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250)
0.1 0.4 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.1 0.6 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.6 GO:0030242 pexophagy(GO:0030242)
0.1 0.6 GO:0046549 retinal cone cell development(GO:0046549)
0.1 0.3 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.4 GO:2001184 regulation of interleukin-12 secretion(GO:2001182) positive regulation of interleukin-12 secretion(GO:2001184)
0.1 0.7 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.2 GO:1904956 regulation of endodermal cell fate specification(GO:0042663) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of heart induction(GO:1901321) regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.1 1.0 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.1 0.2 GO:0010958 regulation of amino acid import(GO:0010958)
0.1 0.3 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.1 0.7 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.1 0.2 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 0.2 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726) positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.1 0.4 GO:0043353 enucleate erythrocyte differentiation(GO:0043353) hydrogen sulfide biosynthetic process(GO:0070814)
0.1 0.4 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1 0.3 GO:0051697 protein delipidation(GO:0051697)
0.1 0.8 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.1 0.3 GO:0016557 peroxisomal membrane transport(GO:0015919) peroxisome membrane biogenesis(GO:0016557) protein import into peroxisome membrane(GO:0045046)
0.1 0.3 GO:0015671 oxygen transport(GO:0015671)
0.1 1.0 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.6 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 0.7 GO:0030149 sphingolipid catabolic process(GO:0030149)
0.1 0.3 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.4 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.0 2.3 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.5 GO:0015884 folic acid transport(GO:0015884)
0.0 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 2.0 GO:0001947 heart looping(GO:0001947)
0.0 0.1 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.5 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.2 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.1 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.8 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.3 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.6 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.4 GO:0007602 phototransduction(GO:0007602)
0.0 0.2 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.2 GO:0018377 N-terminal protein myristoylation(GO:0006499) protein myristoylation(GO:0018377)
0.0 0.3 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.4 GO:0008272 sulfate transport(GO:0008272)
0.0 0.1 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.1 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.2 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.3 GO:0006012 galactose metabolic process(GO:0006012)
0.0 1.4 GO:0007032 endosome organization(GO:0007032)
0.0 0.5 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.3 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.2 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.0 0.1 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.1 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.0 GO:1904798 regulation of core promoter binding(GO:1904796) positive regulation of core promoter binding(GO:1904798)
0.0 5.3 GO:0006275 regulation of DNA replication(GO:0006275)
0.0 1.1 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.3 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 3.6 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.0 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 1.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.4 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.2 GO:0030813 positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.0 0.1 GO:0007403 glial cell fate determination(GO:0007403)
0.0 0.4 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.2 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.3 GO:0023058 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401) adaptation of signaling pathway(GO:0023058)
0.0 0.3 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.9 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.0 0.7 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.1 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334)
0.0 0.4 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 0.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0 0.8 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 1.6 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.2 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.2 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 2.5 GO:0007411 axon guidance(GO:0007411)
0.0 0.1 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.0 0.4 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.0 0.2 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.4 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.7 GO:0006754 ATP biosynthetic process(GO:0006754)
0.0 0.4 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.3 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.2 GO:0030157 pancreatic juice secretion(GO:0030157)
0.0 0.9 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.2 GO:1902624 positive regulation of granulocyte chemotaxis(GO:0071624) positive regulation of neutrophil chemotaxis(GO:0090023) positive regulation of neutrophil migration(GO:1902624)
0.0 0.1 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 0.3 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 1.0 GO:0030518 intracellular steroid hormone receptor signaling pathway(GO:0030518)
0.0 0.2 GO:0097435 fibril organization(GO:0097435)
0.0 1.0 GO:0015718 monocarboxylic acid transport(GO:0015718)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0005594 collagen type IX trimer(GO:0005594)
0.3 1.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.3 1.0 GO:0044307 dendritic branch(GO:0044307)
0.2 0.7 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.2 4.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.2 0.7 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 0.3 GO:0005833 hemoglobin complex(GO:0005833)
0.1 0.9 GO:0070695 FHF complex(GO:0070695)
0.1 4.3 GO:0030673 axolemma(GO:0030673)
0.1 0.9 GO:0033269 internode region of axon(GO:0033269)
0.1 0.3 GO:0000178 cytoplasmic exosome (RNase complex)(GO:0000177) exosome (RNase complex)(GO:0000178)
0.1 0.4 GO:1990032 parallel fiber(GO:1990032)
0.1 1.9 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 1.0 GO:0001739 sex chromatin(GO:0001739)
0.1 0.3 GO:0071914 prominosome(GO:0071914)
0.1 0.9 GO:0030478 actin cap(GO:0030478)
0.1 1.9 GO:0045120 pronucleus(GO:0045120)
0.1 1.6 GO:0010369 chromocenter(GO:0010369)
0.1 0.3 GO:0097447 dendritic tree(GO:0097447)
0.1 0.3 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.4 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 0.6 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 6.6 GO:0072562 blood microparticle(GO:0072562)
0.1 0.5 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 0.6 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.1 0.3 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 0.6 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 1.0 GO:0031932 TORC2 complex(GO:0031932)
0.1 0.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 0.5 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 2.1 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.4 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.6 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.8 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.3 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 1.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.3 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.9 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.2 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.3 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.3 GO:0042588 zymogen granule(GO:0042588)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.2 GO:0030141 secretory granule(GO:0030141) secretory vesicle(GO:0099503)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.5 GO:0043209 myelin sheath(GO:0043209)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.3 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.5 1.6 GO:0001129 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.4 2.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.3 1.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.3 0.8 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.3 6.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 0.7 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.2 0.7 GO:0004458 D-lactate dehydrogenase (cytochrome) activity(GO:0004458) oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor(GO:0016898)
0.2 1.2 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.2 2.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 0.9 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.2 0.5 GO:0051870 methotrexate binding(GO:0051870)
0.1 0.7 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 0.5 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.1 1.9 GO:0043495 protein anchor(GO:0043495)
0.1 0.7 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 0.4 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.1 0.7 GO:0070883 pre-miRNA binding(GO:0070883)
0.1 0.3 GO:0004335 galactokinase activity(GO:0004335)
0.1 0.8 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.6 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 0.3 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 0.3 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.1 0.6 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 0.2 GO:0008527 taste receptor activity(GO:0008527)
0.1 1.0 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.2 GO:0048019 receptor antagonist activity(GO:0048019)
0.1 4.1 GO:0030507 spectrin binding(GO:0030507)
0.1 0.2 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.1 0.4 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 0.2 GO:0097100 supercoiled DNA binding(GO:0097100)
0.1 0.4 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.3 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.6 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.7 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.1 0.6 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 0.3 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.3 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 1.0 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.0 0.9 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.2 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.3 GO:0002054 nucleobase binding(GO:0002054)
0.0 0.3 GO:0019841 retinol binding(GO:0019841)
0.0 0.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.3 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.4 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.0 0.4 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.6 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.7 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.6 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.6 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.2 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.8 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.2 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.3 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.4 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.3 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.6 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.4 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.4 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 1.0 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.6 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 2.2 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)
0.0 1.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.1 GO:0043546 molybdenum ion binding(GO:0030151) molybdopterin cofactor binding(GO:0043546)
0.0 0.1 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.3 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.9 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.1 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.4 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.6 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.1 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.0 0.2 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.2 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.0 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.6 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.4 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 1.1 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.0 0.3 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0 0.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.1 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.3 GO:0016896 exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.0 1.0 GO:0043022 ribosome binding(GO:0043022)
0.0 0.5 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.3 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.0 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.2 GO:0005521 lamin binding(GO:0005521)
0.0 0.4 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 0.7 GO:0005179 hormone activity(GO:0005179)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.1 2.5 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 0.7 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 1.1 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 0.6 PID_CONE_PATHWAY Visual signal transduction: Cones
0.0 1.4 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 1.3 NABA_COLLAGENS Genes encoding collagen proteins
0.0 2.9 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 1.5 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.8 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 0.7 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.0 0.5 PID_ARF6_PATHWAY Arf6 signaling events
0.0 1.0 PID_CXCR3_PATHWAY CXCR3-mediated signaling events
0.0 0.7 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.0 0.4 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.4 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 1.0 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 0.5 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.1 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 0.6 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.5 PID_AURORA_B_PATHWAY Aurora B signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 2.9 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 3.9 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 0.4 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 0.7 REACTOME_MICRORNA_MIRNA_BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 0.4 REACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.1 4.6 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 2.5 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 1.0 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 0.9 REACTOME_ACYL_CHAIN_REMODELLING_OF_PC Genes involved in Acyl chain remodelling of PC
0.0 0.3 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.8 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 1.6 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.9 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.3 REACTOME_COMPLEMENT_CASCADE Genes involved in Complement cascade
0.0 1.1 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.8 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 1.5 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.8 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.2 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.6 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.3 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.5 REACTOME_GENERIC_TRANSCRIPTION_PATHWAY Genes involved in Generic Transcription Pathway
0.0 1.3 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.9 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.9 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.7 REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 1.0 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.2 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.4 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.3 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 1.0 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.5 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.6 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.2 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.3 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.0 0.2 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.0 0.7 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.1 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.5 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.5 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.3 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.1 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.0 0.2 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism