Motif ID: Hif1a

Z-value: 0.659


Transcription factors associated with Hif1a:

Gene SymbolEntrez IDGene Name
Hif1a ENSMUSG00000021109.7 Hif1a

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hif1amm10_v2_chr12_+_73907904_73907970-0.595.5e-05Click!


Activity profile for motif Hif1a.

activity profile for motif Hif1a


Sorted Z-values histogram for motif Hif1a

Sorted Z-values for motif Hif1a



Network of associatons between targets according to the STRING database.



First level regulatory network of Hif1a

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_46845832 3.375 ENSMUST00000048209.9
ENSMUST00000092621.4
Ldha

lactate dehydrogenase A

chr11_-_89302545 2.426 ENSMUST00000061728.3
Nog
noggin
chr19_+_25610533 2.257 ENSMUST00000048935.4
Dmrt3
doublesex and mab-3 related transcription factor 3
chr4_-_55532453 2.152 ENSMUST00000132746.1
ENSMUST00000107619.2
Klf4

Kruppel-like factor 4 (gut)

chr7_-_30973399 1.958 ENSMUST00000098553.4
ENSMUST00000147431.1
Lsr

lipolysis stimulated lipoprotein receptor

chr6_+_88724828 1.923 ENSMUST00000089449.2
Mgll
monoglyceride lipase
chr5_-_135251209 1.884 ENSMUST00000062572.2
Fzd9
frizzled homolog 9 (Drosophila)
chr7_-_30973367 1.865 ENSMUST00000108116.3
Lsr
lipolysis stimulated lipoprotein receptor
chr2_+_27886416 1.769 ENSMUST00000028280.7
Col5a1
collagen, type V, alpha 1
chr1_-_153549697 1.746 ENSMUST00000041874.7
Npl
N-acetylneuraminate pyruvate lyase
chr5_+_129020069 1.584 ENSMUST00000031383.7
ENSMUST00000111343.1
Ran

RAN, member RAS oncogene family

chr1_-_17097839 1.565 ENSMUST00000038382.4
Jph1
junctophilin 1
chr6_+_88724412 1.436 ENSMUST00000113585.2
Mgll
monoglyceride lipase
chrX_-_93832106 1.404 ENSMUST00000045748.6
Pdk3
pyruvate dehydrogenase kinase, isoenzyme 3
chr6_+_88724462 1.359 ENSMUST00000113582.1
Mgll
monoglyceride lipase
chr1_+_74771886 1.343 ENSMUST00000006716.6
Wnt6
wingless-related MMTV integration site 6
chr6_+_88724667 1.342 ENSMUST00000163271.1
Mgll
monoglyceride lipase
chr14_-_20181773 1.332 ENSMUST00000024011.8
Kcnk5
potassium channel, subfamily K, member 5
chr5_-_149051604 1.246 ENSMUST00000093196.4
Hmgb1
high mobility group box 1
chr16_+_70314087 1.240 ENSMUST00000023393.8
Gbe1
glucan (1,4-alpha-), branching enzyme 1
chr17_-_27133620 1.234 ENSMUST00000118613.1
Uqcc2
ubiquinol-cytochrome c reductase complex assembly factor 2
chr6_+_88724489 1.222 ENSMUST00000113581.1
Mgll
monoglyceride lipase
chr4_-_129600642 1.182 ENSMUST00000102593.4
Eif3i
eukaryotic translation initiation factor 3, subunit I
chr16_+_70313949 1.169 ENSMUST00000163832.1
Gbe1
glucan (1,4-alpha-), branching enzyme 1
chr17_+_28769307 1.167 ENSMUST00000004986.6
Mapk13
mitogen-activated protein kinase 13
chr16_-_24393588 1.166 ENSMUST00000181640.1
1110054M08Rik
RIKEN cDNA 1110054M08 gene
chr3_-_101110278 1.134 ENSMUST00000102694.3
Ptgfrn
prostaglandin F2 receptor negative regulator
chr5_-_149051300 1.116 ENSMUST00000110505.1
Hmgb1
high mobility group box 1
chr16_+_70314119 1.075 ENSMUST00000170464.2
Gbe1
glucan (1,4-alpha-), branching enzyme 1
chr11_+_78178651 1.027 ENSMUST00000092880.7
ENSMUST00000127587.1
ENSMUST00000108338.1
Tlcd1


TLC domain containing 1


chr2_+_168081004 1.004 ENSMUST00000052125.6
Pard6b
par-6 (partitioning defective 6) homolog beta (C. elegans)
chr4_-_129600586 0.999 ENSMUST00000135055.1
Eif3i
eukaryotic translation initiation factor 3, subunit I
chr9_+_107569112 0.997 ENSMUST00000010191.7
Hyal2
hyaluronoglucosaminidase 2
chr1_+_55088132 0.979 ENSMUST00000075242.6
Hspe1
heat shock protein 1 (chaperonin 10)
chr14_+_21052574 0.977 ENSMUST00000045376.9
Adk
adenosine kinase
chr8_+_83997613 0.974 ENSMUST00000095228.3
Samd1
sterile alpha motif domain containing 1
chr18_+_74442500 0.956 ENSMUST00000074157.6
Myo5b
myosin VB
chr10_-_78009737 0.943 ENSMUST00000020522.8
Pfkl
phosphofructokinase, liver, B-type
chr11_-_102819663 0.942 ENSMUST00000092567.4
Gjc1
gap junction protein, gamma 1
chr8_-_45999860 0.940 ENSMUST00000053558.9
Ankrd37
ankyrin repeat domain 37
chr9_-_67760208 0.922 ENSMUST00000068526.5
M5C1000I18Rik
RIKEN cDNA M5C1000I18 gene
chr4_+_150236816 0.901 ENSMUST00000080926.6
Eno1
enolase 1, alpha non-neuron
chr6_-_125165707 0.899 ENSMUST00000118875.1
Gapdh
glyceraldehyde-3-phosphate dehydrogenase
chr5_+_108694222 0.891 ENSMUST00000013633.8
ENSMUST00000112560.3
Fgfrl1

fibroblast growth factor receptor-like 1

chr4_-_21685782 0.865 ENSMUST00000076206.4
Prdm13
PR domain containing 13
chr4_+_152325831 0.854 ENSMUST00000103191.4
ENSMUST00000139685.1
Rpl22

ribosomal protein L22

chr17_-_23677432 0.843 ENSMUST00000167059.1
ENSMUST00000024698.8
Tnfrsf12a

tumor necrosis factor receptor superfamily, member 12a

chr17_-_27133902 0.821 ENSMUST00000119227.1
ENSMUST00000025045.8
Uqcc2

ubiquinol-cytochrome c reductase complex assembly factor 2

chr19_+_18713225 0.818 ENSMUST00000055792.7
D030056L22Rik
RIKEN cDNA D030056L22 gene
chr18_+_35553401 0.813 ENSMUST00000181664.1
Snhg4
small nucleolar RNA host gene 4 (non-protein coding)
chr9_-_96364299 0.800 ENSMUST00000034983.5
Atp1b3
ATPase, Na+/K+ transporting, beta 3 polypeptide
chr11_-_115491796 0.797 ENSMUST00000106530.1
ENSMUST00000021082.6
Nt5c

5',3'-nucleotidase, cytosolic

chr14_+_33319703 0.792 ENSMUST00000111955.1
Arhgap22
Rho GTPase activating protein 22
chr8_-_124949165 0.754 ENSMUST00000034469.5
Egln1
EGL nine homolog 1 (C. elegans)
chr8_-_116993459 0.748 ENSMUST00000040484.5
Gcsh
glycine cleavage system protein H (aminomethyl carrier)
chr1_-_161251153 0.738 ENSMUST00000051925.4
ENSMUST00000071718.5
Prdx6

peroxiredoxin 6

chr5_-_135064063 0.737 ENSMUST00000111205.1
ENSMUST00000141309.1
Wbscr22

Williams Beuren syndrome chromosome region 22

chr15_-_75909289 0.731 ENSMUST00000145764.1
ENSMUST00000116440.2
ENSMUST00000151066.1
Eef1d


eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)


chr10_-_85102487 0.726 ENSMUST00000059383.6
Fhl4
four and a half LIM domains 4
chr6_-_85451248 0.715 ENSMUST00000113770.1
ENSMUST00000032080.2
Pradc1

protease-associated domain containing 1

chr15_+_44787746 0.714 ENSMUST00000181839.1
2310069G16Rik
RIKEN cDNA 2310069G16 gene
chr6_-_72958465 0.712 ENSMUST00000114050.1
Tmsb10
thymosin, beta 10
chr4_-_11386757 0.710 ENSMUST00000108313.1
ENSMUST00000108311.2
Esrp1

epithelial splicing regulatory protein 1

chr4_-_139352538 0.688 ENSMUST00000102503.3
Mrto4
MRT4, mRNA turnover 4, homolog (S. cerevisiae)
chr2_-_14055963 0.683 ENSMUST00000091429.5
ENSMUST00000114753.1
Ptpla

protein tyrosine phosphatase-like (proline instead of catalytic arginine), member a

chr15_-_75909319 0.672 ENSMUST00000089680.3
ENSMUST00000141268.1
ENSMUST00000023235.6
ENSMUST00000109972.2
ENSMUST00000089681.5
ENSMUST00000109975.3
ENSMUST00000154584.1
Eef1d






eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)






chr4_-_139352298 0.670 ENSMUST00000030513.6
ENSMUST00000155257.1
Mrto4

MRT4, mRNA turnover 4, homolog (S. cerevisiae)

chr7_-_45466894 0.668 ENSMUST00000033093.8
Bax
BCL2-associated X protein
chr6_+_49073795 0.663 ENSMUST00000128616.1
ENSMUST00000031839.6
ENSMUST00000114500.1
Malsu1


mitochondrial assembly of ribosomal large subunit 1


chr4_+_150237211 0.662 ENSMUST00000133839.1
Eno1
enolase 1, alpha non-neuron
chr2_+_71873224 0.661 ENSMUST00000006669.5
Pdk1
pyruvate dehydrogenase kinase, isoenzyme 1
chr4_+_150236685 0.646 ENSMUST00000150175.1
Eno1
enolase 1, alpha non-neuron
chr14_-_31019055 0.643 ENSMUST00000037739.6
Gnl3
guanine nucleotide binding protein-like 3 (nucleolar)
chr2_-_14056029 0.637 ENSMUST00000074854.7
Ptpla
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member a
chr2_+_156840966 0.606 ENSMUST00000109564.1
Tgif2
TGFB-induced factor homeobox 2
chr8_-_106893581 0.601 ENSMUST00000176437.1
ENSMUST00000177068.1
ENSMUST00000169312.1
ENSMUST00000176515.1
Chtf8



CTF8, chromosome transmission fidelity factor 8



chr6_-_125165576 0.582 ENSMUST00000183272.1
ENSMUST00000182052.1
ENSMUST00000182277.1
Gapdh


glyceraldehyde-3-phosphate dehydrogenase


chr1_+_16665189 0.580 ENSMUST00000177501.1
ENSMUST00000065373.5
Tmem70

transmembrane protein 70

chr14_-_18893749 0.578 ENSMUST00000150727.1
Ube2e2
ubiquitin-conjugating enzyme E2E 2
chr16_+_70314057 0.574 ENSMUST00000171132.1
Gbe1
glucan (1,4-alpha-), branching enzyme 1
chr12_+_105032638 0.568 ENSMUST00000021522.3
Glrx5
glutaredoxin 5 homolog (S. cerevisiae)
chr4_-_133967953 0.555 ENSMUST00000102553.4
Hmgn2
high mobility group nucleosomal binding domain 2
chr7_+_3704025 0.549 ENSMUST00000108623.1
ENSMUST00000139818.1
ENSMUST00000108625.1
Rps9


ribosomal protein S9


chr1_+_120602405 0.543 ENSMUST00000079721.7
En1
engrailed 1
chrX_+_135993820 0.527 ENSMUST00000058119.7
Arxes2
adipocyte-related X-chromosome expressed sequence 2
chr17_+_46681038 0.526 ENSMUST00000002845.6
Mea1
male enhanced antigen 1
chr13_+_90923122 0.515 ENSMUST00000051955.7
Rps23
ribosomal protein S23
chr15_-_31453564 0.506 ENSMUST00000110408.1
Ropn1l
ropporin 1-like
chr5_+_33658123 0.505 ENSMUST00000074849.6
ENSMUST00000079534.4
Tacc3

transforming, acidic coiled-coil containing protein 3

chr8_+_106893616 0.501 ENSMUST00000047629.5
Cirh1a
cirrhosis, autosomal recessive 1A (human)
chr10_-_13193096 0.492 ENSMUST00000019950.4
Ltv1
LTV1 homolog (S. cerevisiae)
chr15_-_75909543 0.485 ENSMUST00000123712.1
ENSMUST00000141475.1
ENSMUST00000144614.1
Eef1d


eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)


chr15_-_93336800 0.483 ENSMUST00000080299.6
Yaf2
YY1 associated factor 2
chrX_+_10717390 0.462 ENSMUST00000115524.1
ENSMUST00000008179.6
Mid1ip1

Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))

chr10_+_36974536 0.458 ENSMUST00000019911.7
Hdac2
histone deacetylase 2
chr2_-_130582554 0.453 ENSMUST00000046001.6
Avp
arginine vasopressin
chr2_+_30807826 0.436 ENSMUST00000041830.3
ENSMUST00000152374.1
Ntmt1

N-terminal Xaa-Pro-Lys N-methyltransferase 1

chr1_+_9545397 0.419 ENSMUST00000072079.7
Rrs1
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr1_+_120340569 0.413 ENSMUST00000037286.8
C1ql2
complement component 1, q subcomponent-like 2
chr2_+_27515157 0.405 ENSMUST00000113952.3
Wdr5
WD repeat domain 5
chr2_-_163419508 0.402 ENSMUST00000046908.3
Oser1
oxidative stress responsive serine rich 1
chr5_+_100039990 0.400 ENSMUST00000169390.1
ENSMUST00000031268.6
Enoph1

enolase-phosphatase 1

chr9_+_106203108 0.392 ENSMUST00000024047.5
Twf2
twinfilin, actin-binding protein, homolog 2 (Drosophila)
chr18_-_3337539 0.392 ENSMUST00000142690.1
ENSMUST00000025069.4
ENSMUST00000082141.5
ENSMUST00000165086.1
ENSMUST00000149803.1
Crem




cAMP responsive element modulator




chr6_+_85451488 0.387 ENSMUST00000032078.6
Cct7
chaperonin containing Tcp1, subunit 7 (eta)
chr16_+_20498817 0.379 ENSMUST00000003320.6
Eif2b5
eukaryotic translation initiation factor 2B, subunit 5 epsilon
chr9_+_21165714 0.379 ENSMUST00000039413.8
Pde4a
phosphodiesterase 4A, cAMP specific
chr3_-_9004686 0.375 ENSMUST00000120143.1
Tpd52
tumor protein D52
chr3_-_9004472 0.365 ENSMUST00000091355.5
ENSMUST00000134788.1
Tpd52

tumor protein D52

chr10_-_127180579 0.359 ENSMUST00000095270.2
Slc26a10
solute carrier family 26, member 10
chr5_+_146948640 0.347 ENSMUST00000146511.1
ENSMUST00000132102.1
Gtf3a

general transcription factor III A

chr11_-_120348475 0.335 ENSMUST00000062147.7
ENSMUST00000128055.1
Actg1

actin, gamma, cytoplasmic 1

chr19_-_45006385 0.331 ENSMUST00000097715.2
Mrpl43
mitochondrial ribosomal protein L43
chr6_-_70792155 0.324 ENSMUST00000066134.5
Rpia
ribose 5-phosphate isomerase A
chr11_+_97315716 0.322 ENSMUST00000019026.3
ENSMUST00000132168.1
Mrpl45

mitochondrial ribosomal protein L45

chr13_-_52981027 0.322 ENSMUST00000071065.7
Nfil3
nuclear factor, interleukin 3, regulated
chr2_-_148875452 0.321 ENSMUST00000028938.6
ENSMUST00000144845.1
Cst3

cystatin C

chr7_-_105736781 0.314 ENSMUST00000033179.6
Rrp8
ribosomal RNA processing 8, methyltransferase, homolog (yeast)
chr10_-_79766872 0.313 ENSMUST00000047203.8
Rnf126
ring finger protein 126
chr9_+_107587711 0.310 ENSMUST00000010192.5
Ifrd2
interferon-related developmental regulator 2
chr18_+_52465676 0.302 ENSMUST00000025406.7
Srfbp1
serum response factor binding protein 1
chr7_+_19004047 0.302 ENSMUST00000053713.3
Irf2bp1
interferon regulatory factor 2 binding protein 1
chr10_-_80387642 0.300 ENSMUST00000062946.6
ENSMUST00000105350.1
Mex3d

mex3 homolog D (C. elegans)

chr10_+_80115779 0.294 ENSMUST00000003152.7
Stk11
serine/threonine kinase 11
chr17_-_45573253 0.293 ENSMUST00000165127.1
ENSMUST00000166469.1
ENSMUST00000024739.7
Hsp90ab1


heat shock protein 90 alpha (cytosolic), class B member 1


chr11_-_120348513 0.292 ENSMUST00000071555.6
Actg1
actin, gamma, cytoplasmic 1
chr1_+_63176818 0.292 ENSMUST00000129339.1
Eef1b2
eukaryotic translation elongation factor 1 beta 2
chr2_+_31887262 0.288 ENSMUST00000138325.1
ENSMUST00000028187.6
Lamc3

laminin gamma 3

chr14_+_5501674 0.285 ENSMUST00000181562.1
Gm3488
predicted gene, 3488
chr5_-_33657889 0.284 ENSMUST00000019439.7
Tmem129
transmembrane protein 129
chr14_-_18893376 0.280 ENSMUST00000151926.1
Ube2e2
ubiquitin-conjugating enzyme E2E 2
chr4_-_62519885 0.270 ENSMUST00000107444.1
ENSMUST00000030090.3
Alad

aminolevulinate, delta-, dehydratase

chr15_-_36608959 0.265 ENSMUST00000001809.8
Pabpc1
poly(A) binding protein, cytoplasmic 1
chr6_+_29272488 0.262 ENSMUST00000115289.1
ENSMUST00000054445.8
Hilpda

hypoxia inducible lipid droplet associated

chr3_+_122245625 0.261 ENSMUST00000178826.1
Gclm
glutamate-cysteine ligase, modifier subunit
chr4_+_129600670 0.259 ENSMUST00000102591.3
ENSMUST00000181579.1
ENSMUST00000173758.1
Tmem234


transmembrane protein 234


chr6_-_29212240 0.258 ENSMUST00000160878.1
ENSMUST00000078155.5
Impdh1

inosine 5'-phosphate dehydrogenase 1

chr9_-_35116804 0.251 ENSMUST00000034537.6
St3gal4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr19_-_44069526 0.249 ENSMUST00000170801.1
Erlin1
ER lipid raft associated 1
chr7_+_89980749 0.246 ENSMUST00000181784.1
Gm26529
predicted gene, 26529
chr7_-_138909492 0.238 ENSMUST00000106112.1
Bnip3
BCL2/adenovirus E1B interacting protein 3
chr14_-_6287250 0.238 ENSMUST00000170104.2
Gm3411
predicted gene 3411
chr7_+_16310412 0.235 ENSMUST00000136781.1
Bbc3
BCL2 binding component 3
chr17_-_46752170 0.230 ENSMUST00000121671.1
ENSMUST00000059844.6
Cnpy3

canopy 3 homolog (zebrafish)

chr19_-_31765027 0.228 ENSMUST00000065067.6
Prkg1
protein kinase, cGMP-dependent, type I
chr6_+_125131869 0.224 ENSMUST00000044200.8
Nop2
NOP2 nucleolar protein
chr13_+_38345716 0.224 ENSMUST00000171970.1
Bmp6
bone morphogenetic protein 6
chr19_-_44069736 0.221 ENSMUST00000172041.1
ENSMUST00000071698.6
ENSMUST00000112028.3
Erlin1


ER lipid raft associated 1


chr13_+_118714678 0.219 ENSMUST00000022246.8
Fgf10
fibroblast growth factor 10
chr4_+_116877376 0.218 ENSMUST00000044823.3
Zswim5
zinc finger SWIM-type containing 5
chr9_-_110654161 0.212 ENSMUST00000133191.1
ENSMUST00000167320.1
Nbeal2

neurobeachin-like 2

chr2_+_162931520 0.211 ENSMUST00000130411.1
Srsf6
serine/arginine-rich splicing factor 6
chr11_-_120348091 0.211 ENSMUST00000106215.4
Actg1
actin, gamma, cytoplasmic 1
chr10_+_128238034 0.207 ENSMUST00000105245.2
Timeless
timeless circadian clock 1
chr10_+_85102627 0.206 ENSMUST00000095383.4
AI597468
expressed sequence AI597468
chr14_-_89898466 0.203 ENSMUST00000081204.4
Gm10110
predicted gene 10110
chr14_-_21052420 0.196 ENSMUST00000154460.1
Ap3m1
adaptor-related protein complex 3, mu 1 subunit
chr17_-_56626872 0.191 ENSMUST00000047226.8
Lonp1
lon peptidase 1, mitochondrial
chr14_+_3332627 0.188 ENSMUST00000177786.1
Gm2956
predicted gene 2956
chr14_+_3572023 0.186 ENSMUST00000178728.1
Gm3005
predicted gene 3005
chr16_+_20673517 0.184 ENSMUST00000115460.1
Eif4g1
eukaryotic translation initiation factor 4, gamma 1
chr19_-_44069690 0.183 ENSMUST00000169092.1
Erlin1
ER lipid raft associated 1
chr3_+_122245557 0.180 ENSMUST00000029769.7
Gclm
glutamate-cysteine ligase, modifier subunit
chr11_+_121259983 0.177 ENSMUST00000106113.1
Foxk2
forkhead box K2
chr3_-_95882193 0.173 ENSMUST00000159863.1
ENSMUST00000159739.1
ENSMUST00000036418.3
Gm129


predicted gene 129


chr10_-_59951753 0.173 ENSMUST00000020308.3
Ddit4
DNA-damage-inducible transcript 4
chr11_-_77489666 0.169 ENSMUST00000037593.7
ENSMUST00000092892.3
Ankrd13b

ankyrin repeat domain 13b

chr12_+_32820304 0.166 ENSMUST00000020886.7
Nampt
nicotinamide phosphoribosyltransferase
chr2_+_127336152 0.161 ENSMUST00000028846.6
Dusp2
dual specificity phosphatase 2
chr17_-_46680870 0.157 ENSMUST00000165007.1
ENSMUST00000071841.5
Klhdc3

kelch domain containing 3

chr7_+_105736565 0.157 ENSMUST00000033182.3
Ilk
integrin linked kinase
chr14_+_4334763 0.150 ENSMUST00000165466.1
2610042L04Rik
RIKEN cDNA 2610042L04 gene
chr4_+_11191354 0.149 ENSMUST00000170901.1
Ccne2
cyclin E2
chr13_-_71963713 0.148 ENSMUST00000077337.8
Irx1
Iroquois related homeobox 1 (Drosophila)
chr1_-_55088024 0.141 ENSMUST00000027123.8
Hspd1
heat shock protein 1 (chaperonin)
chr11_+_60537978 0.138 ENSMUST00000044250.3
Alkbh5
alkB, alkylation repair homolog 5 (E. coli)
chr10_+_122678764 0.137 ENSMUST00000161487.1
ENSMUST00000067918.5
Ppm1h

protein phosphatase 1H (PP2C domain containing)

chr6_-_100287441 0.134 ENSMUST00000101118.2
Rybp
RING1 and YY1 binding protein
chr7_-_44986313 0.132 ENSMUST00000045325.6
ENSMUST00000085387.4
ENSMUST00000107840.1
ENSMUST00000107843.3
ENSMUST00000107842.3
Prmt1




protein arginine N-methyltransferase 1




chr14_-_29721835 0.129 ENSMUST00000022567.7
Cacna2d3
calcium channel, voltage-dependent, alpha2/delta subunit 3
chrX_+_10717451 0.127 ENSMUST00000156321.1
Mid1ip1
Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))
chr14_+_4726775 0.119 ENSMUST00000165619.1
Gm3252
predicted gene 3252
chr15_+_102203639 0.118 ENSMUST00000118729.1
ENSMUST00000119168.1
ENSMUST00000141465.1
ENSMUST00000139960.1
Zfp740



zinc finger protein 740



chr7_+_105736702 0.114 ENSMUST00000163389.1
ENSMUST00000136687.1
Ilk

integrin linked kinase

chr2_-_121140371 0.107 ENSMUST00000099486.2
Lcmt2
leucine carboxyl methyltransferase 2
chr14_+_4182576 0.103 ENSMUST00000164512.1
Gm2974
predicted gene 2974
chr8_-_69974367 0.094 ENSMUST00000116463.2
Gatad2a
GATA zinc finger domain containing 2A
chr14_-_18893623 0.087 ENSMUST00000177259.1
Ube2e2
ubiquitin-conjugating enzyme E2E 2
chr11_-_96065350 0.084 ENSMUST00000100528.4
Ube2z
ubiquitin-conjugating enzyme E2Z (putative)
chr14_-_70443219 0.073 ENSMUST00000180358.1
Polr3d
polymerase (RNA) III (DNA directed) polypeptide D
chr11_+_87127052 0.070 ENSMUST00000041282.6
Trim37
tripartite motif-containing 37
chr4_+_131873608 0.066 ENSMUST00000053819.3
Srsf4
serine/arginine-rich splicing factor 4
chr7_+_98703091 0.065 ENSMUST00000033009.9
Prkrir
protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
chr2_-_121140649 0.048 ENSMUST00000110674.2
Lcmt2
leucine carboxyl methyltransferase 2
chr14_-_70443442 0.046 ENSMUST00000000793.5
Polr3d
polymerase (RNA) III (DNA directed) polypeptide D
chr2_+_124089961 0.041 ENSMUST00000103241.1
Sema6d
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr3_-_58692391 0.030 ENSMUST00000070368.7
Siah2
seven in absentia 2
chr19_+_45006475 0.029 ENSMUST00000026227.2
Peo1
progressive external ophthalmoplegia 1 (human)
chr5_+_124112297 0.028 ENSMUST00000024470.6
ENSMUST00000119269.1
Ogfod2

2-oxoglutarate and iron-dependent oxygenase domain containing 2

chr17_+_53479212 0.028 ENSMUST00000017975.5
Rab5a
RAB5A, member RAS oncogene family

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:1904274 tricellular tight junction assembly(GO:1904274)
1.0 7.3 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.8 2.4 GO:0045819 plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819)
0.8 0.8 GO:0033122 regulation of purine nucleotide catabolic process(GO:0033121) negative regulation of purine nucleotide catabolic process(GO:0033122)
0.7 2.2 GO:0014738 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.7 3.4 GO:0019659 fermentation(GO:0006113) lactate biosynthetic process from pyruvate(GO:0019244) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.6 1.9 GO:1990523 bone regeneration(GO:1990523)
0.6 2.4 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.6 1.8 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.5 2.1 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.4 1.3 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.4 1.5 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.3 1.0 GO:0009153 purine deoxyribonucleotide biosynthetic process(GO:0009153)
0.3 0.9 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.3 0.8 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.3 2.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.2 1.7 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.2 0.7 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.2 0.7 GO:0010248 B cell negative selection(GO:0002352) establishment or maintenance of transmembrane electrochemical gradient(GO:0010248) regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.2 0.7 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.2 2.3 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.2 0.8 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.2 1.0 GO:0042117 monocyte activation(GO:0042117)
0.2 0.8 GO:0006244 pyrimidine nucleotide catabolic process(GO:0006244) pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.2 0.6 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.2 2.1 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.2 1.0 GO:0032439 endosome localization(GO:0032439)
0.2 0.5 GO:0007621 negative regulation of female receptivity(GO:0007621) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of cellular pH reduction(GO:0032847) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 0.5 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.1 0.5 GO:0061743 motor learning(GO:0061743)
0.1 1.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.4 GO:0018201 peptidyl-glycine modification(GO:0018201)
0.1 0.4 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.1 0.4 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.1 0.3 GO:0097278 transforming growth factor beta activation(GO:0036363) complement-dependent cytotoxicity(GO:0097278)
0.1 0.8 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.9 GO:0030388 fructose 6-phosphate metabolic process(GO:0006002) fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.5 GO:0035984 response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.1 0.4 GO:0032532 regulation of microvillus length(GO:0032532)
0.1 0.7 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.6 GO:0009249 protein lipoylation(GO:0009249)
0.1 0.9 GO:0060539 diaphragm development(GO:0060539)
0.1 0.3 GO:0009052 D-ribose metabolic process(GO:0006014) pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.1 0.2 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626) response to cobalt ion(GO:0032025) mitochondrial protein catabolic process(GO:0035694)
0.1 0.2 GO:2000224 regulation of testosterone biosynthetic process(GO:2000224)
0.1 0.1 GO:0060025 regulation of synaptic activity(GO:0060025)
0.1 0.2 GO:0071335 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.1 0.6 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 0.2 GO:0070889 platelet alpha granule organization(GO:0070889)
0.1 0.2 GO:1904975 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
0.1 1.0 GO:1904816 positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.1 1.1 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.2 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.1 0.4 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.1 0.4 GO:0051409 response to nitrosative stress(GO:0051409)
0.1 0.3 GO:0051541 elastin metabolic process(GO:0051541)
0.1 0.3 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.2 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.1 0.3 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.2 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.1 1.9 GO:0009299 mRNA transcription(GO:0009299)
0.0 1.6 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.6 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0 0.1 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.0 0.1 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.2 GO:0032346 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349)
0.0 0.3 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.0 0.5 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.1 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.0 0.7 GO:0046475 bleb assembly(GO:0032060) hydrogen peroxide catabolic process(GO:0042744) glycerophospholipid catabolic process(GO:0046475)
0.0 0.3 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 2.1 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.5 GO:0030953 astral microtubule organization(GO:0030953)
0.0 0.4 GO:0008272 sulfate transport(GO:0008272)
0.0 0.5 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.5 GO:0018126 protein hydroxylation(GO:0018126)
0.0 0.7 GO:0014002 astrocyte development(GO:0014002)
0.0 0.3 GO:0010884 positive regulation of lipid storage(GO:0010884)
0.0 0.6 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.7 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 0.2 GO:0009435 NAD biosynthetic process(GO:0009435)
0.0 0.6 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.0 0.8 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.3 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.9 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 2.3 GO:0006413 translational initiation(GO:0006413)
0.0 0.3 GO:0032288 myelin assembly(GO:0032288)
0.0 0.6 GO:0010470 regulation of gastrulation(GO:0010470)
0.0 0.2 GO:0051195 negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
0.0 1.0 GO:0007043 cell-cell junction assembly(GO:0007043)
0.0 0.0 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.4 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.8 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 0.3 GO:0061157 mRNA destabilization(GO:0061157)
0.0 1.8 GO:0071229 cellular response to acid chemical(GO:0071229)
0.0 0.1 GO:0033522 histone H2A ubiquitination(GO:0033522) histone H2A monoubiquitination(GO:0035518)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.8 GO:0061689 tricellular tight junction(GO:0061689)
0.6 1.8 GO:0005588 collagen type V trimer(GO:0005588)
0.5 1.6 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.5 7.3 GO:0043196 varicosity(GO:0043196)
0.4 2.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.3 1.6 GO:0030314 junctional membrane complex(GO:0030314)
0.2 2.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 2.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.2 3.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.2 0.9 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.2 0.7 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.2 1.5 GO:0097452 GAIT complex(GO:0097452)
0.2 1.0 GO:0045179 apical cortex(GO:0045179)
0.1 0.4 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.1 0.8 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 1.0 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 0.5 GO:0034448 EGO complex(GO:0034448)
0.1 1.9 GO:0031527 filopodium membrane(GO:0031527)
0.1 0.9 GO:0005922 connexon complex(GO:0005922)
0.1 0.6 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.1 0.3 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 0.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.5 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 0.7 GO:0046930 pore complex(GO:0046930)
0.0 0.1 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.0 2.2 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 2.2 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.4 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.4 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 1.1 GO:0043034 costamere(GO:0043034)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 1.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.4 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0034709 methylosome(GO:0034709)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.3 GO:0030686 90S preribosome(GO:0030686)
0.0 0.3 GO:0005604 basement membrane(GO:0005604)
0.0 0.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.3 GO:0005771 multivesicular body(GO:0005771)
0.0 0.3 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.9 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 0.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.8 GO:0032592 integral component of mitochondrial membrane(GO:0032592)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.1 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.8 3.4 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.8 2.4 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.6 7.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.5 2.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.5 1.5 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.4 1.7 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.4 2.2 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.3 0.9 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.3 1.6 GO:0070883 pre-miRNA binding(GO:0070883)
0.2 1.0 GO:0030292 hyalurononglucosaminidase activity(GO:0004415) protein tyrosine kinase inhibitor activity(GO:0030292)
0.2 2.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 0.9 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.2 3.8 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.1 0.4 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.1 0.8 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 1.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 1.8 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.5 GO:0035851 histone deacetylase activity (H4-K16 specific)(GO:0034739) Krueppel-associated box domain binding(GO:0035851)
0.1 0.5 GO:0031893 vasopressin receptor binding(GO:0031893)
0.1 0.9 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.5 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 2.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.7 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 1.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.0 GO:0019206 nucleoside kinase activity(GO:0019206)
0.1 0.8 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.1 0.2 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.1 0.7 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.7 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 0.7 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 1.1 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.1 0.3 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.8 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.2 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.6 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0030519 snoRNP binding(GO:0030519)
0.0 2.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.3 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.0 1.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.4 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.0 0.6 GO:0004707 MAP kinase activity(GO:0004707)
0.0 2.4 GO:0019955 cytokine binding(GO:0019955)
0.0 0.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.6 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 1.3 GO:0042054 histone methyltransferase activity(GO:0042054)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.6 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.3 GO:0030275 LRR domain binding(GO:0030275)
0.0 1.0 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.0 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 1.7 GO:0003735 structural constituent of ribosome(GO:0003735)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 6.9 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.1 2.0 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.1 1.9 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.1 1.2 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 2.4 PID_BMP_PATHWAY BMP receptor signaling
0.0 1.8 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 2.6 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 2.8 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.9 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.4 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.1 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 7.3 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 2.4 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 3.4 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism
0.1 2.2 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 4.6 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.1 4.1 REACTOME_GLUCOSE_METABOLISM Genes involved in Glucose metabolism
0.1 1.0 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 0.8 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.1 0.9 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.1 2.2 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.1 1.6 REACTOME_MICRORNA_MIRNA_BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 1.2 REACTOME_P38MAPK_EVENTS Genes involved in p38MAPK events
0.1 3.2 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 0.5 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.0 0.3 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.8 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.8 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.0 3.2 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.8 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.0 REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.4 REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.0 1.0 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 3.4 REACTOME_TRANSLATION Genes involved in Translation
0.0 1.8 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.3 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.4 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.6 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.3 REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.3 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.7 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.3 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions