Motif ID: Barhl2

Z-value: 0.771


Transcription factors associated with Barhl2:

Gene SymbolEntrez IDGene Name
Barhl2 ENSMUSG00000034384.10 Barhl2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Barhl2mm10_v2_chr5_-_106458440_106458470-0.621.5e-05Click!


Activity profile for motif Barhl2.

activity profile for motif Barhl2


Sorted Z-values histogram for motif Barhl2

Sorted Z-values for motif Barhl2



Network of associatons between targets according to the STRING database.



First level regulatory network of Barhl2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_-_22439719 6.854 ENSMUST00000079601.6
Etv5
ets variant gene 5
chr4_+_154960915 6.178 ENSMUST00000049621.6
Hes5
hairy and enhancer of split 5 (Drosophila)
chr11_+_112782182 5.869 ENSMUST00000000579.2
Sox9
SRY-box containing gene 9
chr18_-_80986578 5.776 ENSMUST00000057950.7
Sall3
sal-like 3 (Drosophila)
chr18_-_78206408 5.257 ENSMUST00000163367.1
Slc14a2
solute carrier family 14 (urea transporter), member 2
chr2_+_59612034 3.444 ENSMUST00000112568.1
ENSMUST00000037526.4
Tanc1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr5_+_110839973 3.400 ENSMUST00000066160.1
Chek2
checkpoint kinase 2
chr17_-_49564262 3.382 ENSMUST00000057610.6
Daam2
dishevelled associated activator of morphogenesis 2
chrX_-_60893430 3.253 ENSMUST00000135107.2
Sox3
SRY-box containing gene 3
chr16_-_22439570 3.244 ENSMUST00000170393.1
Etv5
ets variant gene 5
chr2_+_163225363 3.210 ENSMUST00000099110.3
ENSMUST00000165937.1
Tox2

TOX high mobility group box family member 2

chr2_+_31640037 2.775 ENSMUST00000113470.2
Prdm12
PR domain containing 12
chr18_+_61045139 2.629 ENSMUST00000025522.4
ENSMUST00000115274.1
Pdgfrb

platelet derived growth factor receptor, beta polypeptide

chr4_-_58553553 2.530 ENSMUST00000107575.2
ENSMUST00000107574.1
ENSMUST00000147354.1
Lpar1


lysophosphatidic acid receptor 1


chr3_-_154328634 2.174 ENSMUST00000167744.1
Lhx8
LIM homeobox protein 8
chr2_-_58052832 2.081 ENSMUST00000090940.5
Ermn
ermin, ERM-like protein
chr7_+_127841752 2.035 ENSMUST00000033075.7
Stx4a
syntaxin 4A (placental)
chr7_+_127841817 1.848 ENSMUST00000121705.1
Stx4a
syntaxin 4A (placental)
chr15_-_33405976 1.790 ENSMUST00000079057.6
1700084J12Rik
RIKEN cDNA 1700084J12 gene
chr3_-_27153782 1.742 ENSMUST00000175857.1
ENSMUST00000177055.1
ENSMUST00000176535.1
Ect2


ect2 oncogene


chr3_-_27153844 1.709 ENSMUST00000176242.2
ENSMUST00000176780.1
Ect2

ect2 oncogene

chr4_+_132768325 1.666 ENSMUST00000102561.4
Rpa2
replication protein A2
chr17_-_25727364 1.645 ENSMUST00000170070.1
ENSMUST00000048054.7
Chtf18

CTF18, chromosome transmission fidelity factor 18

chr2_+_118814237 1.551 ENSMUST00000028803.7
ENSMUST00000126045.1
Knstrn

kinetochore-localized astrin/SPAG5 binding

chr3_-_27153861 1.507 ENSMUST00000108300.1
ENSMUST00000108298.2
Ect2

ect2 oncogene

chr5_+_65131184 1.484 ENSMUST00000031089.5
ENSMUST00000101191.3
Klhl5

kelch-like 5

chr19_-_6969746 1.384 ENSMUST00000025912.8
Plcb3
phospholipase C, beta 3
chrX_+_82948861 1.297 ENSMUST00000114000.1
Dmd
dystrophin, muscular dystrophy
chr5_-_110839575 1.255 ENSMUST00000145318.1
Hscb
HscB iron-sulfur cluster co-chaperone homolog (E. coli)
chr12_+_78748947 1.237 ENSMUST00000082024.5
Mpp5
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
chr5_-_37824580 1.233 ENSMUST00000063116.9
Msx1
msh homeobox 1
chr6_-_101377897 1.185 ENSMUST00000075994.6
Pdzrn3
PDZ domain containing RING finger 3
chr2_-_127133909 1.175 ENSMUST00000110387.3
Ncaph
non-SMC condensin I complex, subunit H
chr7_+_79660196 1.088 ENSMUST00000035977.7
Ticrr
TOPBP1-interacting checkpoint and replication regulator
chr8_+_57511833 1.047 ENSMUST00000067925.6
Hmgb2
high mobility group box 2
chr3_-_49757257 1.032 ENSMUST00000035931.7
Pcdh18
protocadherin 18
chr13_-_47106176 1.015 ENSMUST00000021807.6
ENSMUST00000135278.1
Dek

DEK oncogene (DNA binding)

chr5_+_33658123 1.014 ENSMUST00000074849.6
ENSMUST00000079534.4
Tacc3

transforming, acidic coiled-coil containing protein 3

chr15_+_99074968 0.976 ENSMUST00000039665.6
Troap
trophinin associated protein
chr1_-_93343482 0.968 ENSMUST00000128253.1
Pask
PAS domain containing serine/threonine kinase
chr6_-_95718800 0.935 ENSMUST00000079847.5
Suclg2
succinate-Coenzyme A ligase, GDP-forming, beta subunit
chr5_-_110839757 0.925 ENSMUST00000056937.5
Hscb
HscB iron-sulfur cluster co-chaperone homolog (E. coli)
chr6_-_34317442 0.846 ENSMUST00000154655.1
ENSMUST00000102980.4
Akr1b3

aldo-keto reductase family 1, member B3 (aldose reductase)

chr16_-_52296924 0.789 ENSMUST00000167115.1
Alcam
activated leukocyte cell adhesion molecule
chr17_+_35220834 0.788 ENSMUST00000118793.1
Gm16181
predicted gene 16181
chr1_+_165788681 0.759 ENSMUST00000161971.1
ENSMUST00000178336.1
ENSMUST00000005907.5
ENSMUST00000027849.4
Cd247



CD247 antigen



chr16_+_10835046 0.753 ENSMUST00000037913.8
Rmi2
RMI2, RecQ mediated genome instability 2, homolog (S. cerevisiae)
chrX_-_59166080 0.724 ENSMUST00000119306.1
Fgf13
fibroblast growth factor 13
chr9_-_13826946 0.686 ENSMUST00000147115.1
Cep57
centrosomal protein 57
chr2_+_181319714 0.651 ENSMUST00000098971.4
ENSMUST00000054622.8
ENSMUST00000108814.1
ENSMUST00000048608.9
ENSMUST00000108815.1
Rtel1




regulator of telomere elongation helicase 1




chr6_-_8259098 0.580 ENSMUST00000012627.4
Rpa3
replication protein A3
chr13_+_118714678 0.562 ENSMUST00000022246.8
Fgf10
fibroblast growth factor 10
chr8_-_107439585 0.560 ENSMUST00000077208.4
Rps26-ps1
ribosomal protein S26, pseudogene 1
chr7_+_24370255 0.543 ENSMUST00000171904.1
Kcnn4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr10_+_58394381 0.519 ENSMUST00000105468.1
Lims1
LIM and senescent cell antigen-like domains 1
chr7_+_43444104 0.467 ENSMUST00000004729.3
Etfb
electron transferring flavoprotein, beta polypeptide
chr1_-_163725123 0.452 ENSMUST00000159679.1
Mettl11b
methyltransferase like 11B
chr1_+_165788746 0.450 ENSMUST00000161559.2
Cd247
CD247 antigen
chr9_-_13827029 0.449 ENSMUST00000148086.1
ENSMUST00000034398.5
Cep57

centrosomal protein 57

chr11_+_85832551 0.445 ENSMUST00000000095.6
Tbx2
T-box 2
chr17_+_35439155 0.444 ENSMUST00000071951.6
ENSMUST00000078205.7
ENSMUST00000116598.3
ENSMUST00000076256.7
H2-Q7



histocompatibility 2, Q region locus 7



chr4_-_9643638 0.435 ENSMUST00000108333.1
ENSMUST00000108334.1
ENSMUST00000108335.1
ENSMUST00000152526.1
ENSMUST00000103004.3
Asph




aspartate-beta-hydroxylase




chr10_+_80826656 0.431 ENSMUST00000060987.8
ENSMUST00000177850.1
ENSMUST00000180036.1
ENSMUST00000179172.1
Oaz1



ornithine decarboxylase antizyme 1



chr10_+_88459569 0.419 ENSMUST00000020252.3
ENSMUST00000125612.1
Sycp3

synaptonemal complex protein 3

chr17_+_25727726 0.416 ENSMUST00000047273.1
Rpusd1
RNA pseudouridylate synthase domain containing 1
chr11_-_20332689 0.406 ENSMUST00000109594.1
Slc1a4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr6_+_125552948 0.404 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Vwf


Von Willebrand factor homolog


chr12_-_34528844 0.400 ENSMUST00000110819.2
Hdac9
histone deacetylase 9
chr5_+_135168382 0.398 ENSMUST00000111187.3
ENSMUST00000111188.1
Bcl7b

B cell CLL/lymphoma 7B

chr11_-_20332654 0.359 ENSMUST00000004634.6
Slc1a4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr10_-_128626464 0.358 ENSMUST00000026420.5
Rps26
ribosomal protein S26
chr8_+_94214567 0.337 ENSMUST00000079961.6
Nup93
nucleoporin 93
chr7_-_19715395 0.331 ENSMUST00000032555.9
ENSMUST00000093552.5
Tomm40

translocase of outer mitochondrial membrane 40 homolog (yeast)

chrX_+_95711641 0.314 ENSMUST00000150123.1
Zc3h12b
zinc finger CCCH-type containing 12B
chr1_-_171287931 0.312 ENSMUST00000111306.3
ENSMUST00000065941.5
Usp21

ubiquitin specific peptidase 21

chr1_-_153900198 0.302 ENSMUST00000123490.1
5830403L16Rik
RIKEN cDNA 5830403L16 gene
chr1_+_105990652 0.299 ENSMUST00000118196.1
Zcchc2
zinc finger, CCHC domain containing 2
chr6_+_63255971 0.297 ENSMUST00000159561.1
ENSMUST00000095852.3
Grid2

glutamate receptor, ionotropic, delta 2

chrX_-_157415286 0.294 ENSMUST00000079945.4
ENSMUST00000138396.1
Phex

phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)

chr7_+_75848338 0.266 ENSMUST00000092073.5
ENSMUST00000171155.2
Klhl25

kelch-like 25

chr14_+_30825580 0.263 ENSMUST00000006701.5
Tmem110
transmembrane protein 110
chr3_-_80802789 0.252 ENSMUST00000107745.1
ENSMUST00000075316.4
Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr2_+_181319806 0.242 ENSMUST00000153112.1
Rtel1
regulator of telomere elongation helicase 1
chrX_+_71663665 0.236 ENSMUST00000070449.5
Gpr50
G-protein-coupled receptor 50
chr3_+_96629919 0.235 ENSMUST00000048915.6
Rbm8a
RNA binding motif protein 8a
chr18_+_4993795 0.232 ENSMUST00000153016.1
Svil
supervillin
chr18_+_42511496 0.218 ENSMUST00000025375.7
Tcerg1
transcription elongation regulator 1 (CA150)
chr11_+_78261717 0.217 ENSMUST00000010421.6
2610507B11Rik
RIKEN cDNA 2610507B11 gene
chr9_+_61372359 0.214 ENSMUST00000178113.1
ENSMUST00000159386.1
Tle3

transducin-like enhancer of split 3, homolog of Drosophila E(spl)

chr2_+_156008045 0.214 ENSMUST00000006035.6
Ergic3
ERGIC and golgi 3
chr18_+_34736359 0.199 ENSMUST00000105038.2
Gm3550
predicted gene 3550
chr1_-_171287916 0.198 ENSMUST00000111305.1
Usp21
ubiquitin specific peptidase 21
chr1_+_105990384 0.197 ENSMUST00000119166.1
Zcchc2
zinc finger, CCHC domain containing 2
chr19_-_29648355 0.179 ENSMUST00000159692.1
Ermp1
endoplasmic reticulum metallopeptidase 1
chr5_-_120588613 0.179 ENSMUST00000046426.8
Tpcn1
two pore channel 1
chr2_+_156008088 0.172 ENSMUST00000088650.4
Ergic3
ERGIC and golgi 3
chr19_-_12796108 0.170 ENSMUST00000038627.8
Zfp91
zinc finger protein 91
chr10_+_58394361 0.159 ENSMUST00000020077.4
Lims1
LIM and senescent cell antigen-like domains 1
chr5_-_124249758 0.153 ENSMUST00000162812.1
Pitpnm2
phosphatidylinositol transfer protein, membrane-associated 2
chr6_+_8259288 0.146 ENSMUST00000159335.1
Gm16039
predicted gene 16039
chr17_-_26939464 0.128 ENSMUST00000025027.8
ENSMUST00000114935.1
Cuta

cutA divalent cation tolerance homolog (E. coli)

chr5_+_135168283 0.128 ENSMUST00000031692.5
Bcl7b
B cell CLL/lymphoma 7B
chr7_+_25301343 0.125 ENSMUST00000080288.3
Prr19
proline rich 19
chr7_+_128246812 0.114 ENSMUST00000164710.1
ENSMUST00000070656.5
Tgfb1i1

transforming growth factor beta 1 induced transcript 1

chr5_-_134946917 0.111 ENSMUST00000051401.2
Cldn4
claudin 4
chr17_+_79614900 0.107 ENSMUST00000040368.2
Rmdn2
regulator of microtubule dynamics 2
chr5_+_145204523 0.102 ENSMUST00000085671.3
ENSMUST00000031601.7
Zkscan5

zinc finger with KRAB and SCAN domains 5

chr5_+_19907502 0.076 ENSMUST00000101558.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr17_-_34287770 0.067 ENSMUST00000174751.1
ENSMUST00000040655.6
H2-Aa

histocompatibility 2, class II antigen A, alpha

chr7_+_25267669 0.066 ENSMUST00000169266.1
Cic
capicua homolog (Drosophila)
chr6_-_146502099 0.050 ENSMUST00000053273.8
Itpr2
inositol 1,4,5-triphosphate receptor 2
chr1_+_91250482 0.040 ENSMUST00000171112.1
Ube2f
ubiquitin-conjugating enzyme E2F (putative)
chr8_-_83594405 0.035 ENSMUST00000163837.1
Tecr
trans-2,3-enoyl-CoA reductase
chr7_+_128246953 0.033 ENSMUST00000167965.1
Tgfb1i1
transforming growth factor beta 1 induced transcript 1
chr7_+_3629985 0.015 ENSMUST00000008517.6
ENSMUST00000179769.1
Prpf31

PRP31 pre-mRNA processing factor 31 homolog (yeast)

chr11_-_120572822 0.000 ENSMUST00000168360.1
P4hb
prolyl 4-hydroxylase, beta polypeptide

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 10.1 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
2.0 5.9 GO:0035622 intrahepatic bile duct development(GO:0035622) renal vesicle induction(GO:0072034)
1.8 5.3 GO:0071918 urea transmembrane transport(GO:0071918)
1.5 6.2 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
1.3 3.9 GO:0002447 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308) regulation of eosinophil activation(GO:1902566)
0.9 2.6 GO:0035441 cell migration involved in vasculogenesis(GO:0035441)
0.9 3.4 GO:1903463 regulation of mitotic cell cycle DNA replication(GO:1903463)
0.6 2.5 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.6 2.8 GO:1900109 regulation of histone H3-K9 dimethylation(GO:1900109)
0.4 5.8 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.4 1.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.4 1.2 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.4 1.2 GO:2000373 regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.4 6.5 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.3 1.4 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.3 2.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.3 0.8 GO:0006059 hexitol metabolic process(GO:0006059) alditol biosynthetic process(GO:0019401)
0.2 0.9 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990) negative regulation of t-circle formation(GO:1904430)
0.2 1.0 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.2 0.8 GO:0015825 L-serine transport(GO:0015825)
0.2 0.6 GO:0071336 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.2 1.6 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.2 3.3 GO:0007530 sex determination(GO:0007530)
0.1 1.0 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 0.4 GO:0007521 muscle cell fate determination(GO:0007521) mammary placode formation(GO:0060596)
0.1 0.4 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 1.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.1 0.7 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 3.4 GO:0097062 dendritic spine maintenance(GO:0097062)
0.1 0.4 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 1.0 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.1 0.4 GO:0051309 female meiosis chromosome separation(GO:0051309)
0.1 0.9 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.1 0.7 GO:0098909 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.1 2.2 GO:0006298 mismatch repair(GO:0006298)
0.1 1.2 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.1 0.3 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.1 0.5 GO:0046541 saliva secretion(GO:0046541)
0.1 1.0 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 2.2 GO:0021884 forebrain neuron development(GO:0021884)
0.0 1.1 GO:0034453 microtubule anchoring(GO:0034453)
0.0 1.0 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.4 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 1.2 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.4 GO:0031118 rRNA pseudouridine synthesis(GO:0031118) tRNA pseudouridine synthesis(GO:0031119)
0.0 0.3 GO:1904861 excitatory synapse assembly(GO:1904861)
0.0 0.5 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 2.6 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 1.2 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.5 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.8 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.2 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.4 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 2.1 GO:0008360 regulation of cell shape(GO:0008360)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.0 GO:0097149 centralspindlin complex(GO:0097149)
0.6 5.1 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.4 2.2 GO:0001674 female germ cell nucleus(GO:0001674)
0.4 1.2 GO:0000799 nuclear condensin complex(GO:0000799)
0.3 1.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.3 2.1 GO:0033269 internode region of axon(GO:0033269)
0.2 0.8 GO:0097454 Schwann cell microvillus(GO:0097454)
0.2 1.6 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.2 0.9 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1 2.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.4 GO:0000802 transverse filament(GO:0000802)
0.1 0.5 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.1 0.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 1.3 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.8 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 1.5 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.4 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 1.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 2.8 GO:0043198 dendritic shaft(GO:0043198)
0.0 4.6 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 3.6 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.2 GO:0043034 costamere(GO:0043034)
0.0 0.8 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 1.2 GO:0031594 neuromuscular junction(GO:0031594)
0.0 3.5 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.5 GO:0005882 intermediate filament(GO:0005882)
0.0 1.4 GO:0042383 sarcolemma(GO:0042383)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.9 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.9 5.3 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.5 2.6 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.5 5.1 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.4 2.5 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.3 0.9 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.2 1.2 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.2 1.0 GO:0050786 RAGE receptor binding(GO:0050786)
0.2 2.8 GO:1990226 histone methyltransferase binding(GO:1990226)
0.2 0.8 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.2 1.7 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.1 1.6 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.6 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.5 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.4 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.8 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) L-proline transmembrane transporter activity(GO:0015193) alanine transmembrane transporter activity(GO:0022858)
0.1 3.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 1.3 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.5 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.2 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 1.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 8.3 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 1.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.3 GO:0015288 porin activity(GO:0015288)
0.0 0.2 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.4 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.9 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.4 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 1.1 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 5.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 13.5 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 2.2 GO:0051087 chaperone binding(GO:0051087)
0.0 0.4 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 1.2 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.0 0.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.0 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.6 GO:0003684 damaged DNA binding(GO:0003684)
0.0 7.3 GO:0043565 sequence-specific DNA binding(GO:0043565)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 11.3 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.1 2.6 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 3.4 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.1 4.5 PID_PLK1_PATHWAY PLK1 signaling events
0.1 1.4 PID_AURORA_A_PATHWAY Aurora A signaling
0.1 6.1 PID_CDC42_PATHWAY CDC42 signaling events
0.1 1.7 PID_ATR_PATHWAY ATR signaling pathway
0.1 1.4 PID_AR_NONGENOMIC_PATHWAY Nongenotropic Androgen signaling
0.0 2.5 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.0 1.2 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.7 PID_ILK_PATHWAY Integrin-linked kinase signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.4 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.3 5.3 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.2 2.2 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.2 1.2 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2 1.4 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 6.8 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 1.0 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 5.0 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 1.3 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.9 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 2.5 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.6 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 1.3 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.4 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.0 0.7 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.8 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.3 REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus