Motif ID: E2f2_E2f5

Z-value: 3.849

Transcription factors associated with E2f2_E2f5:

Gene SymbolEntrez IDGene Name
E2f2 ENSMUSG00000018983.9 E2f2
E2f5 ENSMUSG00000027552.8 E2f5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
E2f2mm10_v2_chr4_+_136172367_1361723950.904.7e-16Click!
E2f5mm10_v2_chr3_+_14578609_145786870.871.4e-13Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of E2f2_E2f5

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_139543889 40.889 ENSMUST00000174792.1
ENSMUST00000031523.8
Uncx

UNC homeobox

chr4_+_136172367 39.663 ENSMUST00000061721.5
E2f2
E2F transcription factor 2
chr3_+_98013503 38.629 ENSMUST00000079812.6
Notch2
notch 2
chr13_-_24761440 34.342 ENSMUST00000176890.1
ENSMUST00000175689.1
Gmnn

geminin

chr13_-_24761861 33.487 ENSMUST00000006898.3
ENSMUST00000110382.2
Gmnn

geminin

chr2_-_157204483 33.473 ENSMUST00000029170.7
Rbl1
retinoblastoma-like 1 (p107)
chr10_-_69352886 30.727 ENSMUST00000119827.1
ENSMUST00000020099.5
Cdk1

cyclin-dependent kinase 1

chr10_-_60219260 29.589 ENSMUST00000135158.2
Chst3
carbohydrate (chondroitin 6/keratan) sulfotransferase 3
chr8_+_75109528 29.210 ENSMUST00000164309.1
Mcm5
minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)
chr17_+_56304313 29.035 ENSMUST00000113035.1
ENSMUST00000113039.2
ENSMUST00000142387.1
Uhrf1


ubiquitin-like, containing PHD and RING finger domains, 1


chr1_-_20820213 28.811 ENSMUST00000053266.9
Mcm3
minichromosome maintenance deficient 3 (S. cerevisiae)
chr12_+_24708241 27.408 ENSMUST00000020980.5
Rrm2
ribonucleotide reductase M2
chr9_+_122951051 26.007 ENSMUST00000040717.5
Kif15
kinesin family member 15
chr10_+_110745433 25.973 ENSMUST00000174857.1
ENSMUST00000073781.5
ENSMUST00000173471.1
ENSMUST00000173634.1
E2f7



E2F transcription factor 7



chr2_+_72476159 25.161 ENSMUST00000102691.4
Cdca7
cell division cycle associated 7
chr13_-_55329723 25.087 ENSMUST00000021941.7
Mxd3
Max dimerization protein 3
chr2_+_72476225 22.583 ENSMUST00000157019.1
Cdca7
cell division cycle associated 7
chr2_+_119112793 21.720 ENSMUST00000140939.1
ENSMUST00000028795.3
Rad51

RAD51 homolog

chr12_-_69228167 20.856 ENSMUST00000021359.5
Pole2
polymerase (DNA directed), epsilon 2 (p59 subunit)
chr4_+_126556935 19.598 ENSMUST00000048391.8
Clspn
claspin
chr5_+_114130386 19.391 ENSMUST00000031587.6
Ung
uracil DNA glycosylase
chr6_+_4747306 18.883 ENSMUST00000175823.1
ENSMUST00000176204.1
ENSMUST00000166678.1
Peg10


paternally expressed 10


chr13_+_92354783 18.129 ENSMUST00000022218.4
Dhfr
dihydrofolate reductase
chr15_-_55090422 18.050 ENSMUST00000110231.1
ENSMUST00000023059.6
Dscc1

defective in sister chromatid cohesion 1 homolog (S. cerevisiae)

chr15_-_9140374 17.831 ENSMUST00000096482.3
ENSMUST00000110585.2
Skp2

S-phase kinase-associated protein 2 (p45)

chr10_-_5805412 17.596 ENSMUST00000019907.7
Fbxo5
F-box protein 5
chr6_-_88898664 17.164 ENSMUST00000058011.6
Mcm2
minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
chrX_-_51205773 16.669 ENSMUST00000114875.1
Mbnl3
muscleblind-like 3 (Drosophila)
chr1_-_128359610 16.229 ENSMUST00000027601.4
Mcm6
minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)
chr2_-_113848655 15.735 ENSMUST00000102545.1
ENSMUST00000110948.1
Arhgap11a

Rho GTPase activating protein 11A

chr3_-_145649970 15.679 ENSMUST00000029846.3
Cyr61
cysteine rich protein 61
chr7_-_137314394 15.484 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
Ebf3



early B cell factor 3



chr2_+_132816141 15.143 ENSMUST00000028831.8
ENSMUST00000066559.5
Mcm8

minichromosome maintenance deficient 8 (S. cerevisiae)

chr9_+_64281575 15.047 ENSMUST00000034964.6
Tipin
timeless interacting protein
chr4_-_143299498 14.858 ENSMUST00000030317.7
Pdpn
podoplanin
chr4_+_115000156 14.185 ENSMUST00000030490.6
Stil
Scl/Tal1 interrupting locus
chr2_-_113848601 14.152 ENSMUST00000110949.2
Arhgap11a
Rho GTPase activating protein 11A
chr4_+_126556994 13.903 ENSMUST00000147675.1
Clspn
claspin
chr4_-_143299463 13.866 ENSMUST00000119654.1
Pdpn
podoplanin
chr12_+_24708984 13.584 ENSMUST00000154588.1
Rrm2
ribonucleotide reductase M2
chr7_-_48881032 13.051 ENSMUST00000058745.8
E2f8
E2F transcription factor 8
chr1_-_191575534 13.022 ENSMUST00000027933.5
Dtl
denticleless homolog (Drosophila)
chrX_-_93632113 12.994 ENSMUST00000006856.2
Pola1
polymerase (DNA directed), alpha 1
chr17_+_56303396 12.738 ENSMUST00000113038.1
Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
chr14_-_20388822 12.608 ENSMUST00000022345.6
Dnajc9
DnaJ (Hsp40) homolog, subfamily C, member 9
chr14_-_31019055 12.595 ENSMUST00000037739.6
Gnl3
guanine nucleotide binding protein-like 3 (nucleolar)
chr15_-_58135047 12.286 ENSMUST00000038194.3
Atad2
ATPase family, AAA domain containing 2
chrX_-_51205990 12.268 ENSMUST00000114876.2
Mbnl3
muscleblind-like 3 (Drosophila)
chr1_+_184034381 11.651 ENSMUST00000048655.7
Dusp10
dual specificity phosphatase 10
chr7_-_48881596 11.336 ENSMUST00000119223.1
E2f8
E2F transcription factor 8
chr4_+_132768325 11.277 ENSMUST00000102561.4
Rpa2
replication protein A2
chr15_+_102296256 11.088 ENSMUST00000064924.4
Espl1
extra spindle poles-like 1 (S. cerevisiae)
chr12_-_11265768 10.978 ENSMUST00000166117.1
Gen1
Gen homolog 1, endonuclease (Drosophila)
chr13_-_64153194 10.604 ENSMUST00000059817.4
ENSMUST00000117241.1
Zfp367

zinc finger protein 367

chr9_+_44334685 10.586 ENSMUST00000052686.2
H2afx
H2A histone family, member X
chr2_+_150909565 9.889 ENSMUST00000028948.4
Gins1
GINS complex subunit 1 (Psf1 homolog)
chr1_+_157412352 9.780 ENSMUST00000061537.5
2810025M15Rik
RIKEN cDNA 2810025M15 gene
chr2_-_154569845 9.707 ENSMUST00000103145.4
E2f1
E2F transcription factor 1
chr7_+_110122299 9.637 ENSMUST00000033326.8
Wee1
WEE 1 homolog 1 (S. pombe)
chr7_-_44548733 9.631 ENSMUST00000145956.1
ENSMUST00000049343.8
Pold1

polymerase (DNA directed), delta 1, catalytic subunit

chr16_-_15637277 9.561 ENSMUST00000023353.3
Mcm4
minichromosome maintenance deficient 4 homolog (S. cerevisiae)
chr16_-_18248697 9.487 ENSMUST00000115645.3
Ranbp1
RAN binding protein 1
chr1_+_175880775 9.461 ENSMUST00000039725.6
Exo1
exonuclease 1
chr4_+_115000174 9.397 ENSMUST00000129957.1
Stil
Scl/Tal1 interrupting locus
chr14_+_51984826 9.350 ENSMUST00000093813.5
Arhgef40
Rho guanine nucleotide exchange factor (GEF) 40
chr13_+_22035821 9.340 ENSMUST00000110455.2
Hist1h2bk
histone cluster 1, H2bk
chr12_+_112644828 9.319 ENSMUST00000021728.4
ENSMUST00000109755.3
Siva1

SIVA1, apoptosis-inducing factor

chr5_-_77115145 9.196 ENSMUST00000081964.5
Hopx
HOP homeobox
chr13_+_113035111 9.141 ENSMUST00000180543.1
ENSMUST00000181568.1
ENSMUST00000109244.2
ENSMUST00000181117.1
ENSMUST00000181741.1
Cdc20b




cell division cycle 20B




chr9_+_65630552 9.087 ENSMUST00000055844.8
Rbpms2
RNA binding protein with multiple splicing 2
chr17_+_23726336 9.013 ENSMUST00000024701.7
Pkmyt1
protein kinase, membrane associated tyrosine/threonine 1
chr2_-_30474199 8.913 ENSMUST00000065134.2
Ier5l
immediate early response 5-like
chr10_-_21160925 8.627 ENSMUST00000020158.6
Myb
myeloblastosis oncogene
chr9_+_65890237 8.466 ENSMUST00000045802.6
2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr14_+_51984857 8.449 ENSMUST00000100639.4
ENSMUST00000182909.1
ENSMUST00000182760.1
ENSMUST00000182061.1
ENSMUST00000182193.1
Arhgef40




Rho guanine nucleotide exchange factor (GEF) 40




chr16_-_18811615 8.373 ENSMUST00000096990.3
Cdc45
cell division cycle 45
chr9_-_97018823 8.307 ENSMUST00000055433.4
Spsb4
splA/ryanodine receptor domain and SOCS box containing 4
chr5_+_110286306 8.166 ENSMUST00000007296.5
ENSMUST00000112482.1
Pole

polymerase (DNA directed), epsilon

chr4_-_107683576 7.985 ENSMUST00000131776.1
Dmrtb1
DMRT-like family B with proline-rich C-terminal, 1
chrX_+_42151002 7.889 ENSMUST00000123245.1
Stag2
stromal antigen 2
chr13_+_22043189 7.693 ENSMUST00000110452.1
Hist1h2bj
histone cluster 1, H2bj
chr1_+_86526688 7.601 ENSMUST00000045897.8
Ptma
prothymosin alpha
chr13_-_22042949 7.525 ENSMUST00000091741.4
Hist1h2ag
histone cluster 1, H2ag
chr3_+_41563356 7.480 ENSMUST00000163764.1
Phf17
PHD finger protein 17
chr17_+_56303321 7.461 ENSMUST00000001258.8
Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
chr10_+_13090788 7.408 ENSMUST00000121646.1
ENSMUST00000121325.1
ENSMUST00000121766.1
Plagl1


pleiomorphic adenoma gene-like 1


chr7_-_130266237 7.407 ENSMUST00000117872.1
ENSMUST00000120187.1
Fgfr2

fibroblast growth factor receptor 2

chr2_-_5012716 7.353 ENSMUST00000027980.7
Mcm10
minichromosome maintenance deficient 10 (S. cerevisiae)
chr6_+_51470633 7.298 ENSMUST00000114445.1
ENSMUST00000114446.1
ENSMUST00000141711.1
Cbx3


chromobox 3


chr8_-_105707933 7.120 ENSMUST00000013299.9
Enkd1
enkurin domain containing 1
chr14_+_59625281 6.977 ENSMUST00000053949.5
Shisa2
shisa homolog 2 (Xenopus laevis)
chr12_+_116405397 6.891 ENSMUST00000084828.3
Ncapg2
non-SMC condensin II complex, subunit G2
chr2_-_154569720 6.886 ENSMUST00000000894.5
E2f1
E2F transcription factor 1
chrX_-_8074720 6.835 ENSMUST00000115636.3
ENSMUST00000115638.3
Suv39h1

suppressor of variegation 3-9 homolog 1 (Drosophila)

chr7_-_38107490 6.815 ENSMUST00000108023.3
Ccne1
cyclin E1
chr8_+_95633500 6.752 ENSMUST00000034094.9
Gins3
GINS complex subunit 3 (Psf3 homolog)
chr13_-_21783391 6.747 ENSMUST00000099704.3
Hist1h3i
histone cluster 1, H3i
chr2_+_53192067 6.727 ENSMUST00000028336.6
Arl6ip6
ADP-ribosylation factor-like 6 interacting protein 6
chr7_+_13278778 6.682 ENSMUST00000098814.4
ENSMUST00000146998.1
ENSMUST00000185145.1
Lig1


ligase I, DNA, ATP-dependent


chr7_-_130266191 6.641 ENSMUST00000122054.1
Fgfr2
fibroblast growth factor receptor 2
chr13_-_22035589 6.497 ENSMUST00000091742.4
Hist1h2ah
histone cluster 1, H2ah
chr5_+_110839973 6.420 ENSMUST00000066160.1
Chek2
checkpoint kinase 2
chr9_-_20952838 6.310 ENSMUST00000004202.9
Dnmt1
DNA methyltransferase (cytosine-5) 1
chr2_-_132253227 6.147 ENSMUST00000028817.6
Pcna
proliferating cell nuclear antigen
chr11_-_6444352 6.124 ENSMUST00000093346.5
ENSMUST00000109737.2
H2afv

H2A histone family, member V

chr5_+_52741569 6.084 ENSMUST00000031081.4
ENSMUST00000031082.6
Pi4k2b

phosphatidylinositol 4-kinase type 2 beta

chr11_+_80089385 6.010 ENSMUST00000108239.1
ENSMUST00000017694.5
Atad5

ATPase family, AAA domain containing 5

chr1_+_131910458 5.996 ENSMUST00000062264.6
Nucks1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr10_+_128232065 5.976 ENSMUST00000055539.4
ENSMUST00000105244.1
ENSMUST00000105243.2
ENSMUST00000125289.1
ENSMUST00000105242.1
Timeless




timeless circadian clock 1




chr13_+_21787461 5.911 ENSMUST00000110473.2
ENSMUST00000102982.1
Hist1h2bp

histone cluster 1, H2bp

chr13_-_21787218 5.877 ENSMUST00000091751.2
Hist1h2an
histone cluster 1, H2an
chr19_-_10203880 5.807 ENSMUST00000142241.1
ENSMUST00000116542.2
ENSMUST00000025651.5
ENSMUST00000156291.1
Fen1



flap structure specific endonuclease 1



chrX_+_112311334 5.745 ENSMUST00000026599.3
ENSMUST00000113415.1
Apool

apolipoprotein O-like

chrX_+_50841434 5.725 ENSMUST00000114887.2
2610018G03Rik
RIKEN cDNA 2610018G03 gene
chr9_-_36726374 5.693 ENSMUST00000172702.2
ENSMUST00000172742.1
ENSMUST00000034625.5
Chek1


checkpoint kinase 1


chr4_-_107684228 5.656 ENSMUST00000069271.4
Dmrtb1
DMRT-like family B with proline-rich C-terminal, 1
chr13_-_23562369 5.521 ENSMUST00000105107.1
Hist1h3e
histone cluster 1, H3e
chr13_-_23745511 5.498 ENSMUST00000091752.2
Hist1h3c
histone cluster 1, H3c
chr5_-_149051604 5.471 ENSMUST00000093196.4
Hmgb1
high mobility group box 1
chr10_-_7956223 5.466 ENSMUST00000146444.1
Tab2
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr8_+_87472805 5.356 ENSMUST00000180700.2
ENSMUST00000182174.1
ENSMUST00000181159.1
Gm2694


predicted gene 2694


chr9_+_109875541 5.308 ENSMUST00000094324.3
Cdc25a
cell division cycle 25A
chr4_-_132843111 5.252 ENSMUST00000105919.1
ENSMUST00000030702.7
Ppp1r8

protein phosphatase 1, regulatory (inhibitor) subunit 8

chr5_-_110286159 5.177 ENSMUST00000031472.5
Pxmp2
peroxisomal membrane protein 2
chr7_+_79392305 5.169 ENSMUST00000117227.1
ENSMUST00000118959.1
ENSMUST00000036865.6
Fanci


Fanconi anemia, complementation group I


chrX_-_73458990 5.151 ENSMUST00000033737.8
ENSMUST00000077243.4
Haus7

HAUS augmin-like complex, subunit 7

chrX_+_42150672 5.094 ENSMUST00000069619.7
Stag2
stromal antigen 2
chr9_+_103305156 5.085 ENSMUST00000035164.3
Topbp1
topoisomerase (DNA) II binding protein 1
chr1_-_9700209 4.996 ENSMUST00000088658.4
Mybl1
myeloblastosis oncogene-like 1
chr6_+_49822710 4.946 ENSMUST00000031843.6
Npy
neuropeptide Y
chr3_-_95217690 4.890 ENSMUST00000107209.1
Gabpb2
GA repeat binding protein, beta 2
chr9_-_108452377 4.836 ENSMUST00000035232.7
Klhdc8b
kelch domain containing 8B
chr2_+_70474923 4.801 ENSMUST00000100043.2
Sp5
trans-acting transcription factor 5
chr10_+_24595623 4.743 ENSMUST00000176228.1
ENSMUST00000129142.1
Ctgf

connective tissue growth factor

chr5_-_5380185 4.742 ENSMUST00000030763.6
Cdk14
cyclin-dependent kinase 14
chr19_-_5964132 4.715 ENSMUST00000025752.7
ENSMUST00000165143.1
Pola2

polymerase (DNA directed), alpha 2

chr2_-_34913976 4.667 ENSMUST00000028232.3
Phf19
PHD finger protein 19
chr11_+_88718442 4.477 ENSMUST00000138007.1
C030037D09Rik
RIKEN cDNA C030037D09 gene
chr11_+_98907801 4.472 ENSMUST00000092706.6
Cdc6
cell division cycle 6
chr5_-_138172383 4.431 ENSMUST00000000505.9
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr8_+_87472838 4.393 ENSMUST00000180806.2
Gm2694
predicted gene 2694
chr17_+_29490812 4.287 ENSMUST00000024811.6
Pim1
proviral integration site 1
chr4_-_133967953 4.265 ENSMUST00000102553.4
Hmgn2
high mobility group nucleosomal binding domain 2
chr4_+_11191354 4.249 ENSMUST00000170901.1
Ccne2
cyclin E2
chr6_+_113531675 4.245 ENSMUST00000036340.5
ENSMUST00000101051.2
Fancd2

Fanconi anemia, complementation group D2

chr3_-_95217877 4.166 ENSMUST00000136139.1
Gabpb2
GA repeat binding protein, beta 2
chr7_-_100121512 4.093 ENSMUST00000032969.7
Pold3
polymerase (DNA-directed), delta 3, accessory subunit
chr7_+_102441685 4.074 ENSMUST00000033283.9
Rrm1
ribonucleotide reductase M1
chr4_-_93335510 3.978 ENSMUST00000066774.4
Tusc1
tumor suppressor candidate 1
chr14_-_104467984 3.968 ENSMUST00000053016.8
Pou4f1
POU domain, class 4, transcription factor 1
chr13_-_47106176 3.890 ENSMUST00000021807.6
ENSMUST00000135278.1
Dek

DEK oncogene (DNA binding)

chr2_+_85037212 3.822 ENSMUST00000077798.6
Ssrp1
structure specific recognition protein 1
chr13_-_102958084 3.796 ENSMUST00000099202.3
ENSMUST00000172264.1
Mast4

microtubule associated serine/threonine kinase family member 4

chr11_-_100759740 3.718 ENSMUST00000107361.2
Kcnh4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr8_+_72135247 3.715 ENSMUST00000003575.9
Tpm4
tropomyosin 4
chr9_-_72491939 3.701 ENSMUST00000185151.1
ENSMUST00000085358.5
ENSMUST00000184125.1
ENSMUST00000183574.1
ENSMUST00000184831.1
Tex9




testis expressed gene 9




chr10_+_52233612 3.654 ENSMUST00000069004.5
ENSMUST00000105476.2
Dcbld1

discoidin, CUB and LCCL domain containing 1

chr14_-_67933512 3.587 ENSMUST00000039135.4
Dock5
dedicator of cytokinesis 5
chr8_-_53638945 3.552 ENSMUST00000047768.4
Neil3
nei like 3 (E. coli)
chr13_-_21716143 3.550 ENSMUST00000091756.1
Hist1h2bl
histone cluster 1, H2bl
chr6_-_8259098 3.522 ENSMUST00000012627.4
Rpa3
replication protein A3
chr12_+_71016658 3.501 ENSMUST00000125125.1
Arid4a
AT rich interactive domain 4A (RBP1-like)
chr8_+_87473116 3.382 ENSMUST00000182650.1
ENSMUST00000182758.1
ENSMUST00000181898.1
Gm2694


predicted gene 2694


chr17_+_28801090 3.321 ENSMUST00000004985.9
Brpf3
bromodomain and PHD finger containing, 3
chr12_+_111166413 3.320 ENSMUST00000021706.4
Traf3
TNF receptor-associated factor 3
chr18_+_10617768 3.297 ENSMUST00000002551.3
Snrpd1
small nuclear ribonucleoprotein D1
chr2_-_130179310 3.294 ENSMUST00000103199.4
Snrpb
small nuclear ribonucleoprotein B
chr17_+_87975044 3.185 ENSMUST00000005503.3
Msh6
mutS homolog 6 (E. coli)
chr19_+_8723478 3.174 ENSMUST00000180819.1
ENSMUST00000181422.1
Snhg1

small nucleolar RNA host gene (non-protein coding) 1

chr15_-_81871883 3.135 ENSMUST00000023117.8
Phf5a
PHD finger protein 5A
chr9_-_13827029 3.026 ENSMUST00000148086.1
ENSMUST00000034398.5
Cep57

centrosomal protein 57

chr11_+_88068242 3.023 ENSMUST00000018521.4
Vezf1
vascular endothelial zinc finger 1
chr6_+_51470510 3.019 ENSMUST00000031862.7
Cbx3
chromobox 3
chr13_+_21716385 3.018 ENSMUST00000070124.3
Hist1h2ai
histone cluster 1, H2ai
chr18_+_56707725 3.017 ENSMUST00000025486.8
Lmnb1
lamin B1
chrX_-_152016269 3.013 ENSMUST00000026288.4
Ribc1
RIB43A domain with coiled-coils 1
chr12_+_111166349 2.953 ENSMUST00000117269.1
Traf3
TNF receptor-associated factor 3
chr13_+_21754067 2.937 ENSMUST00000091709.2
Hist1h2bn
histone cluster 1, H2bn
chr12_-_80643799 2.907 ENSMUST00000166931.1
Erh
enhancer of rudimentary homolog (Drosophila)
chr9_-_39603635 2.897 ENSMUST00000119722.1
AW551984
expressed sequence AW551984
chr11_-_120581196 2.874 ENSMUST00000067936.5
Arhgdia
Rho GDP dissociation inhibitor (GDI) alpha
chr11_+_69935796 2.862 ENSMUST00000018698.5
Ybx2
Y box protein 2
chr13_-_21833575 2.836 ENSMUST00000081342.5
Hist1h2ap
histone cluster 1, H2ap
chr7_-_45092130 2.820 ENSMUST00000148175.1
Rcn3
reticulocalbin 3, EF-hand calcium binding domain
chr13_-_23761223 2.804 ENSMUST00000102964.2
Hist1h4a
histone cluster 1, H4a
chr3_+_96104498 2.763 ENSMUST00000132980.1
ENSMUST00000138206.1
ENSMUST00000090785.2
ENSMUST00000035519.5
Otud7b



OTU domain containing 7B



chr1_+_15805639 2.736 ENSMUST00000027057.6
Terf1
telomeric repeat binding factor 1
chr7_-_127260677 2.733 ENSMUST00000035276.4
Dctpp1
dCTP pyrophosphatase 1
chr18_+_31789120 2.648 ENSMUST00000025106.3
Polr2d
polymerase (RNA) II (DNA directed) polypeptide D
chr7_+_131542867 2.641 ENSMUST00000046093.5
Hmx3
H6 homeobox 3
chrX_-_59134421 2.615 ENSMUST00000033473.5
Fgf13
fibroblast growth factor 13
chrX_+_162760388 2.607 ENSMUST00000033720.5
ENSMUST00000112327.1
Rbbp7

retinoblastoma binding protein 7

chr7_-_45395672 2.577 ENSMUST00000074575.7
Snrnp70
small nuclear ribonucleoprotein 70 (U1)
chr2_+_85037448 2.534 ENSMUST00000168266.1
ENSMUST00000130729.1
Ssrp1

structure specific recognition protein 1

chr10_+_58323466 2.529 ENSMUST00000020078.7
Lims1
LIM and senescent cell antigen-like domains 1
chr18_-_46198810 2.501 ENSMUST00000167364.1
Trim36
tripartite motif-containing 36
chr11_-_116853083 2.483 ENSMUST00000092404.6
Srsf2
serine/arginine-rich splicing factor 2
chr9_-_111271568 2.474 ENSMUST00000035079.3
Mlh1
mutL homolog 1 (E. coli)
chr6_+_85187438 2.462 ENSMUST00000045942.8
Emx1
empty spiracles homeobox 1
chr3_-_127553233 2.458 ENSMUST00000029588.5
Larp7
La ribonucleoprotein domain family, member 7

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
16.8 50.4 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
12.9 38.6 GO:0035622 intrahepatic bile duct development(GO:0035622) cholangiocyte proliferation(GO:1990705)
9.6 9.6 GO:0045004 DNA replication proofreading(GO:0045004)
8.0 56.3 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
7.2 21.7 GO:0051105 regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
6.8 27.3 GO:0006272 leading strand elongation(GO:0006272)
6.5 19.4 GO:0006285 base-excision repair, AP site formation(GO:0006285)
5.7 28.7 GO:1901731 positive regulation of platelet aggregation(GO:1901731)
5.4 48.7 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
5.1 40.9 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
4.7 14.0 GO:0035604 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) coronal suture morphogenesis(GO:0060365) squamous basal epithelial stem cell differentiation involved in prostate gland acinus development(GO:0060529)
4.5 18.1 GO:0046655 glycine biosynthetic process(GO:0006545) folic acid metabolic process(GO:0046655)
4.4 17.6 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
4.0 55.5 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
3.9 38.6 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
3.8 107.3 GO:0006270 DNA replication initiation(GO:0006270)
3.8 15.0 GO:0000076 DNA replication checkpoint(GO:0000076)
3.6 21.7 GO:0042276 error-prone translesion synthesis(GO:0042276)
3.6 18.1 GO:0034421 post-translational protein acetylation(GO:0034421)
3.5 31.7 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
3.3 23.0 GO:1902969 mitotic DNA replication(GO:1902969)
3.1 15.7 GO:0060591 chondroblast differentiation(GO:0060591)
3.1 27.9 GO:0090166 Golgi disassembly(GO:0090166)
2.7 2.7 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
2.7 45.1 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
2.6 2.6 GO:0031990 mRNA export from nucleus in response to heat stress(GO:0031990)
2.6 23.6 GO:0033504 floor plate development(GO:0033504)
2.3 11.7 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
2.2 8.8 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
2.2 13.0 GO:0019985 translesion synthesis(GO:0019985)
2.0 12.3 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
2.0 6.0 GO:0019046 release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382)
2.0 6.0 GO:1904975 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
1.8 5.5 GO:0045819 plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819)
1.6 17.8 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
1.5 9.2 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
1.4 4.1 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
1.3 4.0 GO:0019230 proprioception(GO:0019230)
1.3 13.0 GO:0000212 meiotic spindle organization(GO:0000212)
1.2 77.4 GO:0008156 negative regulation of DNA replication(GO:0008156)
1.2 16.1 GO:0002385 mucosal immune response(GO:0002385)
1.2 2.5 GO:0051311 meiotic metaphase plate congression(GO:0051311)
1.2 11.0 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
1.2 6.0 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
1.2 3.6 GO:0001193 maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193)
1.2 4.7 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
1.2 5.8 GO:0043137 DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
1.2 2.3 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
1.0 4.1 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
1.0 9.1 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
1.0 3.0 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
1.0 25.9 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
1.0 1.0 GO:0060821 inactivation of X chromosome by DNA methylation(GO:0060821)
1.0 3.9 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.9 5.7 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.9 12.6 GO:1904816 positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.9 3.6 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.9 0.9 GO:1900452 regulation of long term synaptic depression(GO:1900452)
0.9 1.8 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.9 8.8 GO:0008063 Toll signaling pathway(GO:0008063)
0.9 4.3 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.8 2.4 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.8 8.6 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.8 9.3 GO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901030)
0.8 2.3 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.8 6.8 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.8 31.9 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.7 2.9 GO:0001887 selenium compound metabolic process(GO:0001887) selenocysteine metabolic process(GO:0016259)
0.7 1.4 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.7 2.1 GO:0007341 penetration of zona pellucida(GO:0007341)
0.7 2.1 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.7 4.1 GO:0042148 strand invasion(GO:0042148)
0.6 2.5 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.6 4.2 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.6 3.5 GO:0034773 histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.6 2.9 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.6 1.7 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.6 9.7 GO:0006298 mismatch repair(GO:0006298)
0.5 2.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.5 6.9 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.5 1.6 GO:0006597 spermine biosynthetic process(GO:0006597)
0.5 2.0 GO:0070836 caveola assembly(GO:0070836)
0.5 40.3 GO:0006342 chromatin silencing(GO:0006342)
0.5 14.0 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.5 3.6 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.4 4.4 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.4 1.3 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.4 2.1 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.4 7.6 GO:0043486 histone exchange(GO:0043486)
0.4 1.2 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.4 1.5 GO:0046125 pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.4 4.9 GO:0030238 male sex determination(GO:0030238)
0.4 2.6 GO:0098909 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.4 5.7 GO:0042407 cristae formation(GO:0042407)
0.4 3.9 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.3 2.3 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.3 4.9 GO:0032098 regulation of appetite(GO:0032098)
0.3 1.0 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.3 5.2 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095) mitotic G2/M transition checkpoint(GO:0044818)
0.3 1.3 GO:0060056 mammary gland involution(GO:0060056)
0.3 2.5 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.3 6.2 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.3 17.2 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.3 2.1 GO:0009249 protein lipoylation(GO:0009249)
0.3 2.3 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.3 1.0 GO:0044330 canonical Wnt signaling pathway involved in positive regulation of wound healing(GO:0044330) lactic acid secretion(GO:0046722) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.3 7.0 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.3 12.6 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.2 4.8 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.2 1.4 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.2 1.6 GO:0072697 protein localization to cell cortex(GO:0072697)
0.2 5.3 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.2 0.7 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.2 1.8 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.2 1.0 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) negative regulation by host of viral genome replication(GO:0044828)
0.2 0.6 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.2 0.6 GO:0019401 alditol biosynthetic process(GO:0019401)
0.2 4.2 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.2 6.6 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.2 4.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.2 0.9 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.2 3.0 GO:0034453 microtubule anchoring(GO:0034453)
0.2 1.7 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.2 2.4 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.2 1.4 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.2 2.5 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.1 4.0 GO:0048255 mRNA stabilization(GO:0048255)
0.1 5.5 GO:0045860 positive regulation of protein kinase activity(GO:0045860)
0.1 5.7 GO:0006289 nucleotide-excision repair(GO:0006289)
0.1 0.4 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.1 7.6 GO:0006334 nucleosome assembly(GO:0006334)
0.1 1.4 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 3.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 11.4 GO:0035308 negative regulation of protein dephosphorylation(GO:0035308)
0.1 1.2 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 0.7 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 0.4 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630) positive regulation of aminoacyl-tRNA ligase activity(GO:1903632)
0.1 2.4 GO:0035315 hair cell differentiation(GO:0035315) auditory receptor cell differentiation(GO:0042491)
0.1 3.6 GO:0060135 maternal process involved in female pregnancy(GO:0060135)
0.1 0.9 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 0.3 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.1 0.9 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.3 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.1 2.5 GO:0007340 acrosome reaction(GO:0007340)
0.1 2.9 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.1 4.8 GO:0043966 histone H3 acetylation(GO:0043966)
0.1 14.9 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.1 1.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 1.0 GO:0007569 cell aging(GO:0007569)
0.1 1.2 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.1 2.3 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.1 1.3 GO:0000338 protein deneddylation(GO:0000338)
0.1 1.5 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.1 4.7 GO:0048863 stem cell differentiation(GO:0048863)
0.1 11.9 GO:0006260 DNA replication(GO:0006260)
0.1 5.2 GO:0051225 spindle assembly(GO:0051225)
0.1 1.9 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.1 0.2 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1 0.4 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 3.0 GO:0001885 endothelial cell development(GO:0001885)
0.1 0.8 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.3 GO:0006020 inositol metabolic process(GO:0006020)
0.0 1.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.9 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 1.9 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 1.1 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 1.1 GO:0051028 mRNA transport(GO:0051028)
0.0 1.4 GO:0016925 protein sumoylation(GO:0016925)
0.0 1.0 GO:0006397 mRNA processing(GO:0006397)
0.0 1.3 GO:0001656 metanephros development(GO:0001656)
0.0 0.4 GO:0006103 2-oxoglutarate metabolic process(GO:0006103)
0.0 1.9 GO:0030010 establishment of cell polarity(GO:0030010)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
9.9 9.9 GO:0000811 GINS complex(GO:0000811)
9.0 45.1 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
7.9 118.5 GO:0042555 MCM complex(GO:0042555)
5.9 29.3 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
4.1 29.0 GO:0031298 replication fork protection complex(GO:0031298)
3.5 17.7 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
3.3 16.6 GO:0035189 Rb-E2F complex(GO:0035189)
3.2 9.6 GO:0043625 delta DNA polymerase complex(GO:0043625)
3.2 28.7 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
2.0 6.1 GO:0070557 PCNA-p21 complex(GO:0070557)
2.0 18.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
1.6 88.0 GO:0005657 replication fork(GO:0005657)
1.5 10.5 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
1.4 4.2 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
1.4 6.8 GO:0033553 rDNA heterochromatin(GO:0033553)
1.3 22.9 GO:0000800 lateral element(GO:0000800)
1.1 2.1 GO:0000785 chromatin(GO:0000785)
1.0 1.0 GO:0001740 Barr body(GO:0001740)
0.9 9.5 GO:0034709 methylosome(GO:0034709)
0.9 4.7 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.9 7.6 GO:0001673 male germ cell nucleus(GO:0001673)
0.9 13.0 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.8 2.4 GO:0018444 translation release factor complex(GO:0018444)
0.8 2.3 GO:0035061 interchromatin granule(GO:0035061)
0.7 4.5 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.7 48.3 GO:0000786 nucleosome(GO:0000786)
0.7 2.1 GO:0001651 dense fibrillar component(GO:0001651)
0.7 6.9 GO:0044815 DNA packaging complex(GO:0044815)
0.6 5.2 GO:0070652 HAUS complex(GO:0070652)
0.6 30.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.6 5.7 GO:0061617 MICOS complex(GO:0061617)
0.6 1.2 GO:0000801 central element(GO:0000801)
0.6 8.8 GO:0035631 CD40 receptor complex(GO:0035631)
0.6 11.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.6 9.5 GO:1904115 axon cytoplasm(GO:1904115)
0.5 1.4 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.5 2.7 GO:0070187 telosome(GO:0070187)
0.4 3.0 GO:0005638 lamin filament(GO:0005638)
0.4 7.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.4 25.7 GO:0005871 kinesin complex(GO:0005871)
0.4 58.3 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.3 1.7 GO:0044611 nuclear pore inner ring(GO:0044611)
0.3 3.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.3 1.8 GO:0044530 supraspliceosomal complex(GO:0044530)
0.3 4.4 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.3 2.6 GO:0000243 commitment complex(GO:0000243)
0.3 3.7 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.3 77.9 GO:0005667 transcription factor complex(GO:0005667)
0.3 1.9 GO:0005827 polar microtubule(GO:0005827)
0.3 18.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.3 1.8 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.3 1.8 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.2 0.9 GO:0001652 granular component(GO:0001652)
0.2 21.2 GO:0005814 centriole(GO:0005814)
0.2 1.0 GO:0033503 HULC complex(GO:0033503)
0.2 3.1 GO:0005686 U2 snRNP(GO:0005686)
0.2 2.1 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.2 5.2 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.2 2.1 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.2 11.8 GO:0072686 mitotic spindle(GO:0072686)
0.1 4.2 GO:0001772 immunological synapse(GO:0001772)
0.1 7.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 1.1 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 0.9 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 3.8 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 32.7 GO:0043235 receptor complex(GO:0043235)
0.1 4.7 GO:0005801 cis-Golgi network(GO:0005801)
0.1 14.4 GO:0005819 spindle(GO:0005819)
0.1 1.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 8.4 GO:0000781 chromosome, telomeric region(GO:0000781)
0.1 1.9 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.1 1.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 3.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 21.2 GO:0000139 Golgi membrane(GO:0000139)
0.1 4.2 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 1.6 GO:0032993 protein-DNA complex(GO:0032993)
0.1 0.9 GO:0097470 ribbon synapse(GO:0097470)
0.0 12.3 GO:0000790 nuclear chromatin(GO:0000790)
0.0 1.4 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 4.4 GO:0043195 terminal bouton(GO:0043195)
0.0 21.4 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.4 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 1.1 GO:0016592 mediator complex(GO:0016592)
0.0 0.4 GO:0005642 annulate lamellae(GO:0005642)
0.0 2.3 GO:0005902 microvillus(GO:0005902)
0.0 1.3 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.4 GO:0030686 90S preribosome(GO:0030686)
0.0 0.8 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 2.6 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 1.7 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 179.3 GO:0005634 nucleus(GO:0005634)
0.0 1.3 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.2 GO:0097440 apical dendrite(GO:0097440)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 2.4 GO:0005925 focal adhesion(GO:0005925)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
12.3 49.2 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
9.0 45.1 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
7.4 29.6 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
6.0 18.1 GO:0051870 methotrexate binding(GO:0051870)
5.6 33.5 GO:0010997 anaphase-promoting complex binding(GO:0010997)
4.8 19.4 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
4.4 62.1 GO:0003688 DNA replication origin binding(GO:0003688)
3.7 25.8 GO:0000150 recombinase activity(GO:0000150)
2.9 17.6 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
2.9 28.7 GO:0008517 folic acid transporter activity(GO:0008517)
2.5 17.6 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
2.4 36.4 GO:0035173 histone kinase activity(GO:0035173)
2.1 8.2 GO:0071987 WD40-repeat domain binding(GO:0071987)
2.0 6.1 GO:0030337 mismatch base pair DNA N-glycosylase activity(GO:0000700) DNA polymerase processivity factor activity(GO:0030337)
1.9 48.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
1.9 5.8 GO:0048256 flap endonuclease activity(GO:0048256)
1.8 11.0 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
1.8 5.5 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
1.8 3.6 GO:0000405 bubble DNA binding(GO:0000405)
1.6 18.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
1.6 14.0 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
1.3 44.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
1.2 4.9 GO:0045131 pre-mRNA branch point binding(GO:0045131)
1.2 6.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
1.2 13.9 GO:0031996 thioesterase binding(GO:0031996)
1.1 6.8 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
1.1 6.7 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
1.1 3.3 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
1.1 14.0 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
1.0 38.6 GO:0051059 NF-kappaB binding(GO:0051059)
0.9 2.8 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.8 5.9 GO:1990446 U1 snRNP binding(GO:1990446)
0.8 5.0 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.8 39.7 GO:0003678 DNA helicase activity(GO:0003678)
0.8 12.0 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.8 64.0 GO:0070491 repressing transcription factor binding(GO:0070491)
0.8 10.5 GO:1990226 histone methyltransferase binding(GO:1990226)
0.7 2.9 GO:0070279 vitamin B6 binding(GO:0070279)
0.7 2.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.7 15.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.7 5.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.6 13.7 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.6 14.8 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.5 9.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.5 9.4 GO:0070182 DNA polymerase binding(GO:0070182)
0.5 3.7 GO:0070492 oligosaccharide binding(GO:0070492)
0.5 101.9 GO:0001047 core promoter binding(GO:0001047)
0.5 16.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.5 1.4 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.4 4.0 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.4 4.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.4 2.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.4 1.5 GO:0001884 pyrimidine nucleoside binding(GO:0001884) deoxynucleoside kinase activity(GO:0019136)
0.4 4.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.3 2.8 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.3 37.5 GO:0004386 helicase activity(GO:0004386)
0.3 1.3 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.3 2.2 GO:0070697 activin receptor binding(GO:0070697)
0.3 25.7 GO:0003777 microtubule motor activity(GO:0003777)
0.3 2.4 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.3 0.9 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.3 2.0 GO:0000400 four-way junction DNA binding(GO:0000400)
0.3 1.3 GO:0004594 pantothenate kinase activity(GO:0004594)
0.2 4.9 GO:0005184 neuropeptide hormone activity(GO:0005184) neuropeptide receptor binding(GO:0071855)
0.2 1.5 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.2 9.2 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.2 3.0 GO:0008432 JUN kinase binding(GO:0008432)
0.2 1.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.2 9.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.2 31.0 GO:0042393 histone binding(GO:0042393)
0.2 7.3 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.2 0.7 GO:0051425 PTB domain binding(GO:0051425)
0.2 6.3 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.2 0.9 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.2 1.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.2 2.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 2.3 GO:0070411 I-SMAD binding(GO:0070411)
0.1 7.1 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 17.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 0.6 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.1 0.4 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 12.2 GO:0031072 heat shock protein binding(GO:0031072)
0.1 4.7 GO:0030332 cyclin binding(GO:0030332)
0.1 4.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 1.4 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 1.4 GO:0031386 protein tag(GO:0031386)
0.1 3.7 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.4 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 0.9 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 5.3 GO:0051087 chaperone binding(GO:0051087)
0.1 1.7 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 1.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 22.0 GO:0005096 GTPase activator activity(GO:0005096)
0.1 1.6 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 17.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 4.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 3.2 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 1.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 1.0 GO:0048038 quinone binding(GO:0048038)
0.1 2.6 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 90.5 GO:0003677 DNA binding(GO:0003677)
0.1 1.4 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 1.3 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 1.2 GO:0070840 dynein complex binding(GO:0070840)
0.1 0.9 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 1.6 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 0.4 GO:0008097 5S rRNA binding(GO:0008097)
0.0 2.3 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 3.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.3 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 2.1 GO:0019842 vitamin binding(GO:0019842)
0.0 9.0 GO:0061659 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 1.1 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.6 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.4 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.8 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.5 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 3.6 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.9 GO:0002039 p53 binding(GO:0002039)
0.0 2.0 GO:0005178 integrin binding(GO:0005178)
0.0 1.6 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.3 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 1.9 GO:0003735 structural constituent of ribosome(GO:0003735)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
5.7 51.4 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
4.8 67.3 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
2.8 124.3 PID_ATR_PATHWAY ATR signaling pathway
2.2 176.9 PID_E2F_PATHWAY E2F transcription factor network
1.2 15.7 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.9 24.3 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.8 23.6 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.7 69.1 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.6 32.5 PID_PLK1_PATHWAY PLK1 signaling events
0.5 15.3 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.5 41.5 PID_NOTCH_PATHWAY Notch signaling pathway
0.4 6.1 PID_BARD1_PATHWAY BARD1 signaling events
0.4 8.8 PID_CD40_PATHWAY CD40/CD40L signaling
0.3 13.1 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.3 10.2 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.3 8.4 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.3 13.9 PID_IL4_2PATHWAY IL4-mediated signaling events
0.3 14.0 PID_FGF_PATHWAY FGF signaling pathway
0.2 6.2 PID_ERBB4_PATHWAY ErbB4 signaling events
0.1 6.4 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 5.3 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.1 6.4 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.1 4.9 PID_RAC1_PATHWAY RAC1 signaling pathway
0.1 1.4 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 1.4 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.1 1.3 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.1 3.0 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.1 4.8 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 2.5 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.1 2.3 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.0 0.9 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.9 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 1.7 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 3.9 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 0.2 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.0 0.2 PID_ATF2_PATHWAY ATF-2 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
9.8 107.5 REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
8.9 159.8 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
8.6 138.4 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
4.1 57.5 REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
3.4 37.1 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
2.9 5.8 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
2.8 11.4 REACTOME_LAGGING_STRAND_SYNTHESIS Genes involved in Lagging Strand Synthesis
2.7 32.3 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
2.4 21.8 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
2.1 36.5 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
1.6 31.7 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
1.5 7.4 REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Activation of the pre-replicative complex
1.3 14.0 REACTOME_FGFR2C_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR2c ligand binding and activation
1.1 4.2 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
1.0 26.0 REACTOME_KINESINS Genes involved in Kinesins
0.9 9.0 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.9 45.6 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.8 8.8 REACTOME_ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.6 17.5 REACTOME_G1_PHASE Genes involved in G1 Phase
0.5 2.7 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.4 6.8 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.4 6.1 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.4 10.5 REACTOME_RNA_POL_I_TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
0.4 7.3 REACTOME_TRANSCRIPTION_COUPLED_NER_TC_NER Genes involved in Transcription-coupled NER (TC-NER)
0.3 2.1 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.3 3.5 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.3 3.3 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.2 1.2 REACTOME_TRAF6_MEDIATED_INDUCTION_OF_TAK1_COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.2 1.9 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.2 32.0 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.2 4.1 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 4.7 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2 1.4 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 6.8 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.1 3.7 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.1 11.0 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 1.4 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.1 4.4 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.1 1.3 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 2.6 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 2.5 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.6 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.3 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 1.5 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.1 2.4 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 1.5 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 2.7 REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.1 3.5 REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE Genes involved in Late Phase of HIV Life Cycle
0.1 0.9 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 5.6 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 4.9 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 0.9 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 0.9 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 2.4 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.1 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 8.6 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.6 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME_PLATELET_SENSITIZATION_BY_LDL Genes involved in Platelet sensitization by LDL
0.0 1.1 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.6 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 1.3 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 0.4 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.4 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.2 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 Genes involved in Activation of Genes by ATF4