Motif ID: Hoxd11_Cdx1_Hoxc11

Z-value: 0.825

Transcription factors associated with Hoxd11_Cdx1_Hoxc11:

Gene SymbolEntrez IDGene Name
Cdx1 ENSMUSG00000024619.8 Cdx1
Hoxc11 ENSMUSG00000001656.3 Hoxc11
Hoxd11 ENSMUSG00000042499.12 Hoxd11






Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxd11_Cdx1_Hoxc11

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_144893127 10.653 ENSMUST00000142808.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr13_-_84064772 10.311 ENSMUST00000182477.1
Gm17750
predicted gene, 17750
chr4_+_144892813 7.147 ENSMUST00000105744.1
ENSMUST00000171001.1
Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr1_+_159737510 6.144 ENSMUST00000111669.3
Tnr
tenascin R
chr4_+_144893077 5.683 ENSMUST00000154208.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr17_+_3397189 4.790 ENSMUST00000072156.6
Tiam2
T cell lymphoma invasion and metastasis 2
chr5_-_62766153 4.576 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr6_+_80018877 3.692 ENSMUST00000147663.1
ENSMUST00000128718.1
ENSMUST00000126005.1
ENSMUST00000133918.1
Lrrtm4



leucine rich repeat transmembrane neuronal 4



chr3_-_49757257 3.663 ENSMUST00000035931.7
Pcdh18
protocadherin 18
chr1_+_19103022 3.647 ENSMUST00000037294.7
Tfap2d
transcription factor AP-2, delta
chr4_-_154636831 3.376 ENSMUST00000030902.6
ENSMUST00000105637.1
ENSMUST00000070313.7
ENSMUST00000105636.1
ENSMUST00000105638.2
ENSMUST00000097759.2
ENSMUST00000124771.1
Prdm16






PR domain containing 16






chr3_+_62419668 3.359 ENSMUST00000161057.1
Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr18_+_69593361 3.344 ENSMUST00000114978.2
ENSMUST00000114977.1
Tcf4

transcription factor 4

chr7_-_142661858 3.160 ENSMUST00000145896.2
Igf2
insulin-like growth factor 2
chr7_-_73537621 3.021 ENSMUST00000172704.1
Chd2
chromodomain helicase DNA binding protein 2
chr1_-_56969864 2.927 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr3_+_66985680 2.718 ENSMUST00000065047.6
Rsrc1
arginine/serine-rich coiled-coil 1
chr17_+_31433054 2.612 ENSMUST00000136384.1
Pde9a
phosphodiesterase 9A
chr4_-_88033328 2.539 ENSMUST00000078090.5
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr1_-_56969827 2.532 ENSMUST00000176759.1
Satb2
special AT-rich sequence binding protein 2
chr17_-_91092715 2.391 ENSMUST00000160800.2
ENSMUST00000159778.1
ENSMUST00000160844.3
Nrxn1


neurexin I


chr16_+_11405648 2.385 ENSMUST00000096273.2
Snx29
sorting nexin 29
chr6_-_13839916 2.290 ENSMUST00000060442.7
Gpr85
G protein-coupled receptor 85
chr13_-_101692624 2.272 ENSMUST00000035532.6
Pik3r1
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)
chr6_-_97617536 2.223 ENSMUST00000113355.2
Frmd4b
FERM domain containing 4B
chr16_+_42907563 2.173 ENSMUST00000151244.1
ENSMUST00000114694.2
Zbtb20

zinc finger and BTB domain containing 20

chr18_-_42899470 2.139 ENSMUST00000120632.1
Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr10_+_69787431 2.102 ENSMUST00000183240.1
Ank3
ankyrin 3, epithelial
chr2_-_66410064 2.060 ENSMUST00000112366.1
Scn1a
sodium channel, voltage-gated, type I, alpha
chr3_+_108591279 2.030 ENSMUST00000051145.8
ENSMUST00000139626.1
Wdr47

WD repeat domain 47

chr15_+_81936911 1.973 ENSMUST00000135663.1
Csdc2
cold shock domain containing C2, RNA binding
chr15_+_81936753 1.933 ENSMUST00000038757.7
Csdc2
cold shock domain containing C2, RNA binding
chr1_+_81077274 1.919 ENSMUST00000068275.5
ENSMUST00000113494.2
Nyap2

neuronal tyrosine-phophorylated phosphoinositide 3-kinase adaptor 2

chr17_-_35074485 1.897 ENSMUST00000007259.3
Ly6g6d
lymphocyte antigen 6 complex, locus G6D
chr1_+_81077204 1.765 ENSMUST00000123720.1
Nyap2
neuronal tyrosine-phophorylated phosphoinositide 3-kinase adaptor 2
chr15_+_100761741 1.651 ENSMUST00000023776.6
Slc4a8
solute carrier family 4 (anion exchanger), member 8
chr9_-_55919605 1.624 ENSMUST00000037408.8
Scaper
S phase cyclin A-associated protein in the ER
chr7_-_29906087 1.595 ENSMUST00000053521.8
Zfp27
zinc finger protein 27
chr2_+_32395896 1.530 ENSMUST00000028162.3
Ptges2
prostaglandin E synthase 2
chr7_-_27181149 1.473 ENSMUST00000071986.6
ENSMUST00000121848.1
Mia

melanoma inhibitory activity

chr9_+_62858085 1.430 ENSMUST00000034777.6
ENSMUST00000163820.1
Calml4

calmodulin-like 4

chr6_+_125215551 1.426 ENSMUST00000032487.7
ENSMUST00000100942.2
ENSMUST00000063588.8
Vamp1


vesicle-associated membrane protein 1


chr16_+_10812915 1.336 ENSMUST00000115822.1
Gm11172
predicted gene 11172
chr16_-_32877723 1.324 ENSMUST00000119810.1
1700021K19Rik
RIKEN cDNA 1700021K19 gene
chr5_-_73256555 1.310 ENSMUST00000101127.5
ENSMUST00000171179.1
Fryl
Fryl
furry homolog-like (Drosophila)
furry homolog-like (Drosophila)
chr10_+_116177351 1.307 ENSMUST00000155606.1
ENSMUST00000128399.1
Ptprr

protein tyrosine phosphatase, receptor type, R

chr6_+_125552948 1.291 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Vwf


Von Willebrand factor homolog


chr5_-_62765618 1.266 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr14_+_76504185 1.254 ENSMUST00000177207.1
Tsc22d1
TSC22 domain family, member 1
chr7_+_25306085 1.241 ENSMUST00000119703.1
ENSMUST00000108409.1
Tmem145

transmembrane protein 145

chr2_-_31845925 1.229 ENSMUST00000028188.7
Fibcd1
fibrinogen C domain containing 1
chr4_+_31964081 1.202 ENSMUST00000037607.4
ENSMUST00000080933.6
ENSMUST00000108183.1
ENSMUST00000108184.2
Map3k7



mitogen-activated protein kinase kinase kinase 7



chr2_-_45112890 1.146 ENSMUST00000076836.6
Zeb2
zinc finger E-box binding homeobox 2
chr9_-_44799179 1.135 ENSMUST00000114705.1
ENSMUST00000002100.7
Tmem25

transmembrane protein 25

chr18_-_62756275 1.097 ENSMUST00000067450.1
ENSMUST00000048109.5
2700046A07Rik

RIKEN cDNA 2700046A07 gene

chr1_-_155099630 1.077 ENSMUST00000055322.4
Ier5
immediate early response 5
chr4_-_11981265 1.075 ENSMUST00000098260.2
Gm10604
predicted gene 10604
chrX_+_150547375 1.044 ENSMUST00000066337.6
ENSMUST00000112715.1
Alas2

aminolevulinic acid synthase 2, erythroid

chr8_+_57455898 1.030 ENSMUST00000034023.3
Scrg1
scrapie responsive gene 1
chr5_+_107497718 0.969 ENSMUST00000112671.2
A830010M20Rik
RIKEN cDNA A830010M20 gene
chr1_-_72536930 0.968 ENSMUST00000047786.5
March4
membrane-associated ring finger (C3HC4) 4
chr14_+_28511344 0.966 ENSMUST00000112272.1
Wnt5a
wingless-related MMTV integration site 5A
chrX_-_12673540 0.963 ENSMUST00000060108.6
1810030O07Rik
RIKEN cDNA 1810030O07 gene
chr13_+_80883403 0.948 ENSMUST00000099356.2
Arrdc3
arrestin domain containing 3
chr1_+_45311538 0.897 ENSMUST00000087883.6
Col3a1
collagen, type III, alpha 1
chr18_-_42899294 0.863 ENSMUST00000117687.1
Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr2_-_170194033 0.858 ENSMUST00000180625.1
Gm17619
predicted gene, 17619
chr19_+_60755947 0.847 ENSMUST00000088237.4
Nanos1
nanos homolog 1 (Drosophila)
chr5_+_107497762 0.828 ENSMUST00000152474.1
ENSMUST00000060553.7
A830010M20Rik

RIKEN cDNA A830010M20 gene

chr2_-_114013619 0.810 ENSMUST00000090275.4
Gjd2
gap junction protein, delta 2
chr1_-_157256682 0.809 ENSMUST00000134543.1
Rasal2
RAS protein activator like 2
chr17_-_90455872 0.808 ENSMUST00000174337.1
ENSMUST00000172466.1
Nrxn1

neurexin I

chr11_+_29463735 0.804 ENSMUST00000155854.1
Ccdc88a
coiled coil domain containing 88A
chr18_-_35498856 0.803 ENSMUST00000025215.8
Sil1
endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae)
chr6_-_122340499 0.795 ENSMUST00000160843.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr12_+_55836365 0.793 ENSMUST00000059250.6
Brms1l
breast cancer metastasis-suppressor 1-like
chr16_-_4880284 0.786 ENSMUST00000037843.6
Ubald1
UBA-like domain containing 1
chr18_+_35770318 0.776 ENSMUST00000165299.1
Gm16490
predicted gene 16490
chr10_-_105574435 0.761 ENSMUST00000061506.8
Tmtc2
transmembrane and tetratricopeptide repeat containing 2
chr7_-_134232005 0.752 ENSMUST00000134504.1
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr2_-_33086366 0.744 ENSMUST00000049618.2
Garnl3
GTPase activating RANGAP domain-like 3
chr4_-_64046925 0.719 ENSMUST00000107377.3
Tnc
tenascin C
chr13_-_23622502 0.703 ENSMUST00000062045.2
Hist1h1e
histone cluster 1, H1e
chr2_+_29965560 0.684 ENSMUST00000113717.1
ENSMUST00000113719.2
ENSMUST00000100225.2
ENSMUST00000113741.1
ENSMUST00000095083.4
ENSMUST00000046257.7
Sptan1





spectrin alpha, non-erythrocytic 1





chr2_-_27463994 0.683 ENSMUST00000164296.1
Brd3
bromodomain containing 3
chr3_+_66985947 0.658 ENSMUST00000161726.1
ENSMUST00000160504.1
Rsrc1

arginine/serine-rich coiled-coil 1

chr1_-_165934900 0.638 ENSMUST00000069609.5
ENSMUST00000111427.2
ENSMUST00000111426.4
Pou2f1


POU domain, class 2, transcription factor 1


chr1_+_180109192 0.637 ENSMUST00000143176.1
ENSMUST00000135056.1
Cdc42bpa

CDC42 binding protein kinase alpha

chr16_-_35769356 0.623 ENSMUST00000023554.8
Dirc2
disrupted in renal carcinoma 2 (human)
chr6_-_112947246 0.618 ENSMUST00000088373.4
Srgap3
SLIT-ROBO Rho GTPase activating protein 3
chr9_-_42124276 0.609 ENSMUST00000060989.8
Sorl1
sortilin-related receptor, LDLR class A repeats-containing
chr18_+_37655891 0.602 ENSMUST00000097608.2
3222401L13Rik
RIKEN cDNA 3222401L13 gene
chr16_-_91728701 0.600 ENSMUST00000114023.2
ENSMUST00000117644.1
Cryzl1

crystallin, zeta (quinone reductase)-like 1

chr3_-_87768932 0.587 ENSMUST00000173184.1
ENSMUST00000172621.1
ENSMUST00000174759.1
ENSMUST00000172590.1
ENSMUST00000079083.5
Pear1




platelet endothelial aggregation receptor 1




chr16_-_91728599 0.583 ENSMUST00000122254.1
Cryzl1
crystallin, zeta (quinone reductase)-like 1
chr17_-_51826562 0.583 ENSMUST00000024720.4
ENSMUST00000129667.1
ENSMUST00000156051.1
ENSMUST00000169480.1
ENSMUST00000148559.1
Satb1




special AT-rich sequence binding protein 1




chr1_+_153874335 0.577 ENSMUST00000055314.3
Gm5531
predicted gene 5531
chr10_-_25200110 0.555 ENSMUST00000100012.2
Akap7
A kinase (PRKA) anchor protein 7
chr2_-_116064721 0.547 ENSMUST00000110906.2
Meis2
Meis homeobox 2
chr6_+_8259288 0.538 ENSMUST00000159335.1
Gm16039
predicted gene 16039
chr18_+_36939178 0.531 ENSMUST00000115662.2
Pcdha2
protocadherin alpha 2
chr3_+_66985647 0.529 ENSMUST00000162362.1
ENSMUST00000065074.7
Rsrc1

arginine/serine-rich coiled-coil 1

chr12_+_33147754 0.525 ENSMUST00000146040.1
ENSMUST00000125192.1
Atxn7l1

ataxin 7-like 1

chr8_+_121116163 0.519 ENSMUST00000054691.6
Foxc2
forkhead box C2
chr4_+_136284658 0.518 ENSMUST00000144217.1
Zfp46
zinc finger protein 46
chr10_+_90071095 0.516 ENSMUST00000183109.1
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr1_-_176807124 0.504 ENSMUST00000057037.7
Cep170
centrosomal protein 170
chr10_+_119992916 0.500 ENSMUST00000105261.2
Grip1
glutamate receptor interacting protein 1
chr2_+_116067213 0.496 ENSMUST00000152412.1
G630016G05Rik
RIKEN cDNA G630016G05 gene
chr10_+_42583787 0.495 ENSMUST00000105497.1
ENSMUST00000144806.1
Ostm1

osteopetrosis associated transmembrane protein 1

chr4_+_136284708 0.487 ENSMUST00000130223.1
Zfp46
zinc finger protein 46
chr12_+_105453831 0.475 ENSMUST00000178224.1
D430019H16Rik
RIKEN cDNA D430019H16 gene
chr7_+_103550368 0.473 ENSMUST00000106888.1
Olfr613
olfactory receptor 613
chr5_+_150259922 0.472 ENSMUST00000087204.5
Fry
furry homolog (Drosophila)
chr4_+_11758147 0.471 ENSMUST00000029871.5
ENSMUST00000108303.1
Cdh17

cadherin 17

chr12_-_31950535 0.463 ENSMUST00000172314.2
Hbp1
high mobility group box transcription factor 1
chr1_-_45503282 0.462 ENSMUST00000086430.4
Col5a2
collagen, type V, alpha 2
chr3_+_88965812 0.457 ENSMUST00000090933.4
Ash1l
ash1 (absent, small, or homeotic)-like (Drosophila)
chr9_-_110624361 0.447 ENSMUST00000035069.9
Nradd
neurotrophin receptor associated death domain
chr15_-_42676967 0.446 ENSMUST00000022921.5
Angpt1
angiopoietin 1
chrX_-_105928547 0.426 ENSMUST00000101305.2
Atrx
alpha thalassemia/mental retardation syndrome X-linked homolog (human)
chr3_+_5218516 0.425 ENSMUST00000175866.1
Zfhx4
zinc finger homeodomain 4
chr2_+_36230426 0.423 ENSMUST00000062069.5
Ptgs1
prostaglandin-endoperoxide synthase 1
chr2_-_116067391 0.407 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chrX_+_20364481 0.402 ENSMUST00000033372.6
ENSMUST00000115391.1
ENSMUST00000115387.1
Rp2h


retinitis pigmentosa 2 homolog (human)


chr11_-_109298090 0.399 ENSMUST00000106704.2
Rgs9
regulator of G-protein signaling 9
chr5_-_73191848 0.397 ENSMUST00000176910.1
Fryl
furry homolog-like (Drosophila)
chr13_-_99344652 0.391 ENSMUST00000022153.6
Ptcd2
pentatricopeptide repeat domain 2
chr10_-_30655859 0.386 ENSMUST00000092610.4
Ncoa7
nuclear receptor coactivator 7
chr19_-_46395722 0.383 ENSMUST00000040270.4
Actr1a
ARP1 actin-related protein 1A, centractin alpha
chr3_+_66985700 0.381 ENSMUST00000046542.6
ENSMUST00000162693.1
Rsrc1

arginine/serine-rich coiled-coil 1

chr11_+_97798995 0.380 ENSMUST00000143571.1
Lasp1
LIM and SH3 protein 1
chr1_+_89454769 0.378 ENSMUST00000027521.8
ENSMUST00000074945.5
Agap1

ArfGAP with GTPase domain, ankyrin repeat and PH domain 1

chr2_-_79456750 0.370 ENSMUST00000041099.4
Neurod1
neurogenic differentiation 1
chr18_-_37020679 0.365 ENSMUST00000097612.2
Gm10545
predicted gene 10545
chr9_-_123678782 0.362 ENSMUST00000170591.1
ENSMUST00000171647.1
Slc6a20a

solute carrier family 6 (neurotransmitter transporter), member 20A

chr9_-_123678873 0.360 ENSMUST00000040960.6
Slc6a20a
solute carrier family 6 (neurotransmitter transporter), member 20A
chr16_+_32877775 0.354 ENSMUST00000023489.4
ENSMUST00000171325.1
Fyttd1

forty-two-three domain containing 1

chr17_-_78985428 0.352 ENSMUST00000118991.1
Prkd3
protein kinase D3
chr7_-_134232125 0.352 ENSMUST00000127524.1
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr4_+_11704439 0.348 ENSMUST00000108304.2
Gem
GTP binding protein (gene overexpressed in skeletal muscle)
chr6_-_119388671 0.339 ENSMUST00000169744.1
Adipor2
adiponectin receptor 2
chr4_+_62286441 0.335 ENSMUST00000084530.2
Slc31a2
solute carrier family 31, member 2
chr3_-_89349968 0.334 ENSMUST00000074582.6
ENSMUST00000107448.2
ENSMUST00000029676.5
Adam15


a disintegrin and metallopeptidase domain 15 (metargidin)


chr3_+_5218589 0.332 ENSMUST00000177488.1
Zfhx4
zinc finger homeodomain 4
chr4_-_47057296 0.325 ENSMUST00000107747.1
ENSMUST00000084616.2
Anks6

ankyrin repeat and sterile alpha motif domain containing 6

chr3_-_89349939 0.311 ENSMUST00000107446.1
Adam15
a disintegrin and metallopeptidase domain 15 (metargidin)
chr11_-_103267405 0.311 ENSMUST00000021324.2
Map3k14
mitogen-activated protein kinase kinase kinase 14
chr7_-_141435327 0.309 ENSMUST00000138865.1
Slc25a22
solute carrier family 25 (mitochondrial carrier, glutamate), member 22
chr11_-_84067063 0.307 ENSMUST00000108101.1
Dusp14
dual specificity phosphatase 14
chr3_-_144760841 0.301 ENSMUST00000059091.5
Clca1
chloride channel calcium activated 1
chr14_+_66868850 0.300 ENSMUST00000100453.1
Gm5464
predicted gene 5464
chr7_-_141434532 0.293 ENSMUST00000133021.1
ENSMUST00000106007.3
ENSMUST00000150026.1
ENSMUST00000133206.2
Slc25a22



solute carrier family 25 (mitochondrial carrier, glutamate), member 22



chr5_+_145204523 0.292 ENSMUST00000085671.3
ENSMUST00000031601.7
Zkscan5

zinc finger with KRAB and SCAN domains 5

chr6_-_144209448 0.289 ENSMUST00000077160.5
Sox5
SRY-box containing gene 5
chr1_+_63176818 0.286 ENSMUST00000129339.1
Eef1b2
eukaryotic translation elongation factor 1 beta 2
chr5_-_24030649 0.285 ENSMUST00000030849.6
Fam126a
family with sequence similarity 126, member A
chr6_-_144209558 0.283 ENSMUST00000111749.1
ENSMUST00000170367.2
Sox5

SRY-box containing gene 5

chr5_-_25100624 0.277 ENSMUST00000030784.7
Prkag2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr2_-_24048857 0.273 ENSMUST00000114497.1
Hnmt
histamine N-methyltransferase
chr8_+_40307458 0.267 ENSMUST00000068999.7
Micu3
mitochondrial calcium uptake family, member 3
chr2_+_69670100 0.247 ENSMUST00000100050.3
Klhl41
kelch-like 41
chr18_-_6490808 0.247 ENSMUST00000028100.6
ENSMUST00000050542.5
Epc1

enhancer of polycomb homolog 1 (Drosophila)

chr11_-_109298066 0.237 ENSMUST00000106706.1
Rgs9
regulator of G-protein signaling 9
chr17_-_35910032 0.237 ENSMUST00000141662.1
ENSMUST00000056034.6
ENSMUST00000077494.6
ENSMUST00000149277.1
ENSMUST00000061052.5
Atat1




alpha tubulin acetyltransferase 1




chr11_-_109298121 0.232 ENSMUST00000020920.3
Rgs9
regulator of G-protein signaling 9
chr6_-_144209471 0.231 ENSMUST00000038815.7
Sox5
SRY-box containing gene 5
chr7_-_119895446 0.229 ENSMUST00000098080.2
Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr19_-_45812291 0.227 ENSMUST00000086993.4
Kcnip2
Kv channel-interacting protein 2
chr3_+_66219909 0.224 ENSMUST00000029421.5
Ptx3
pentraxin related gene
chr11_+_115933282 0.221 ENSMUST00000140991.1
Sap30bp
SAP30 binding protein
chrX_+_82948861 0.216 ENSMUST00000114000.1
Dmd
dystrophin, muscular dystrophy
chr1_-_105659008 0.214 ENSMUST00000070699.8
Pign
phosphatidylinositol glycan anchor biosynthesis, class N
chr1_+_12692430 0.209 ENSMUST00000180062.1
ENSMUST00000177608.1
Sulf1

sulfatase 1

chr3_-_89960562 0.204 ENSMUST00000069805.7
Atp8b2
ATPase, class I, type 8B, member 2
chr7_+_45062429 0.201 ENSMUST00000107830.1
ENSMUST00000003513.3
ENSMUST00000107829.1
ENSMUST00000150609.1
Nosip



nitric oxide synthase interacting protein



chr4_-_82850721 0.200 ENSMUST00000139401.1
Zdhhc21
zinc finger, DHHC domain containing 21
chr4_+_108479081 0.194 ENSMUST00000155068.1
Zcchc11
zinc finger, CCHC domain containing 11
chr11_-_110251736 0.190 ENSMUST00000044003.7
Abca6
ATP-binding cassette, sub-family A (ABC1), member 6
chr4_+_102254739 0.188 ENSMUST00000106907.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr3_+_5218546 0.186 ENSMUST00000026284.6
Zfhx4
zinc finger homeodomain 4
chr14_+_32085804 0.183 ENSMUST00000170600.1
ENSMUST00000168986.1
ENSMUST00000169649.1
Oxnad1


oxidoreductase NAD-binding domain containing 1


chr13_-_98890974 0.182 ENSMUST00000179301.1
ENSMUST00000179271.1
Tnpo1

transportin 1

chr11_+_77216180 0.179 ENSMUST00000037912.5
ENSMUST00000156488.1
Ssh2

slingshot homolog 2 (Drosophila)

chr2_+_178141920 0.176 ENSMUST00000103066.3
Phactr3
phosphatase and actin regulator 3
chr13_-_56895737 0.172 ENSMUST00000022023.6
ENSMUST00000109871.1
Trpc7

transient receptor potential cation channel, subfamily C, member 7

chr1_-_74600564 0.170 ENSMUST00000127938.1
ENSMUST00000154874.1
Rnf25

ring finger protein 25

chr1_-_152625212 0.167 ENSMUST00000027760.7
Rgl1
ral guanine nucleotide dissociation stimulator,-like 1
chr3_-_95106779 0.166 ENSMUST00000005768.7
ENSMUST00000107232.2
ENSMUST00000107236.2
Pip5k1a


phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha


chr16_-_55838827 0.165 ENSMUST00000096026.2
ENSMUST00000036273.6
ENSMUST00000114457.1
Nfkbiz


nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta


chr2_+_116900152 0.163 ENSMUST00000126467.1
ENSMUST00000128305.1
ENSMUST00000155323.1
D330050G23Rik


RIKEN cDNA D330050G23 gene


chr6_+_87981683 0.162 ENSMUST00000143871.1
ENSMUST00000153372.1
Gm5577

predicted gene 5577

chr19_-_6067785 0.157 ENSMUST00000162575.1
ENSMUST00000159084.1
ENSMUST00000161718.1
ENSMUST00000162810.1
ENSMUST00000025713.5
ENSMUST00000113543.2
ENSMUST00000161528.1
Tm7sf2






transmembrane 7 superfamily member 2






chr1_-_144177259 0.153 ENSMUST00000111941.1
ENSMUST00000052375.1
Rgs13

regulator of G-protein signaling 13

chr2_-_29787622 0.150 ENSMUST00000177467.1
ENSMUST00000113807.3
Trub2

TruB pseudouridine (psi) synthase homolog 2 (E. coli)

chr8_+_25720054 0.138 ENSMUST00000068916.8
ENSMUST00000139836.1
Ppapdc1b

phosphatidic acid phosphatase type 2 domain containing 1B

chr3_-_19264959 0.136 ENSMUST00000121951.1
Pde7a
phosphodiesterase 7A
chr17_+_73804841 0.134 ENSMUST00000024860.7
Ehd3
EH-domain containing 3
chr1_+_58445151 0.131 ENSMUST00000087521.6
ENSMUST00000114337.1
Nif3l1

Ngg1 interacting factor 3-like 1 (S. pombe)

chr2_-_180824596 0.129 ENSMUST00000148700.1
Gm14340
predicted gene 14340

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 23.5 GO:0042572 retinol metabolic process(GO:0042572)
1.5 6.1 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.8 3.2 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
0.4 3.4 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.4 3.2 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.3 5.5 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.3 1.3 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.3 1.0 GO:0061349 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) hypophysis morphogenesis(GO:0048850) cervix development(GO:0060067) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354)
0.3 0.9 GO:0090327 negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.3 3.3 GO:0042118 endothelial cell activation(GO:0042118)
0.2 1.2 GO:0019236 response to pheromone(GO:0019236)
0.2 1.2 GO:0097343 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.2 3.0 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.2 2.1 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.2 2.3 GO:0010459 negative regulation of heart rate(GO:0010459)
0.2 2.2 GO:0090527 actin filament reorganization(GO:0090527)
0.2 4.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.2 3.7 GO:1901629 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688) regulation of presynaptic membrane organization(GO:1901629)
0.2 2.1 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 1.1 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.2 0.7 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.2 0.9 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 0.5 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.2 0.8 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.2 3.4 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.2 3.0 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.2 0.5 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 0.6 GO:2001137 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953) positive regulation of endocytic recycling(GO:2001137)
0.1 0.4 GO:0030210 heparin biosynthetic process(GO:0030210) Tie signaling pathway(GO:0048014)
0.1 2.4 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 2.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 1.1 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.1 0.4 GO:0097393 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
0.1 0.4 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.1 4.1 GO:0046677 response to antibiotic(GO:0046677)
0.1 0.7 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.6 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 0.4 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 0.6 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 0.6 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 1.5 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.1 0.8 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.1 0.7 GO:0015838 amino-acid betaine transport(GO:0015838)
0.1 0.2 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.1 1.4 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 0.2 GO:0008228 opsonization(GO:0008228)
0.1 0.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 0.3 GO:0001692 histamine metabolic process(GO:0001692) imidazole-containing compound catabolic process(GO:0052805)
0.1 0.5 GO:0002674 negative regulation of acute inflammatory response(GO:0002674)
0.1 1.9 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.1 1.0 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.1 0.6 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.1 2.2 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.5 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.1 0.4 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.3 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 0.2 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 1.9 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.0 0.6 GO:1900153 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.5 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.6 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 3.9 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.4 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.3 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.2 GO:0061042 vascular wound healing(GO:0061042)
0.0 0.2 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.8 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.2 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841)
0.0 0.6 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 2.5 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.0 1.1 GO:0030901 midbrain development(GO:0030901)
0.0 0.2 GO:0031272 regulation of pseudopodium assembly(GO:0031272) regulation of myoblast proliferation(GO:2000291)
0.0 0.2 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 1.5 GO:0051453 regulation of intracellular pH(GO:0051453)
0.0 0.1 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.2 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.5 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.1 GO:1901387 Golgi to lysosome transport(GO:0090160) positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.8 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.0 0.7 GO:0051693 actin filament capping(GO:0051693)
0.0 1.7 GO:0001889 liver development(GO:0001889)
0.0 0.1 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.3 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 1.7 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.3 GO:0015813 L-glutamate transport(GO:0015813)
0.0 0.3 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 1.6 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.0 GO:0035588 G-protein coupled purinergic receptor signaling pathway(GO:0035588) purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.1 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.2 GO:0045116 protein neddylation(GO:0045116)
0.0 0.5 GO:0008542 visual learning(GO:0008542)
0.0 0.3 GO:1902476 chloride transmembrane transport(GO:1902476)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 6.1 GO:0072534 perineuronal net(GO:0072534)
0.4 3.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.3 1.4 GO:0070820 tertiary granule(GO:0070820)
0.3 1.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.2 4.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 0.5 GO:0005588 collagen type V trimer(GO:0005588)
0.1 2.1 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.7 GO:0032437 cuticular plate(GO:0032437)
0.1 0.4 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.1 2.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.9 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 2.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.9 GO:0001739 sex chromatin(GO:0001739)
0.1 1.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 3.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 3.2 GO:0016235 aggresome(GO:0016235)
0.1 0.8 GO:0005922 connexon complex(GO:0005922)
0.1 0.8 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 5.6 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 2.5 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.7 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 1.7 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.4 GO:0002177 manchette(GO:0002177)
0.0 0.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 2.4 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.6 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.9 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0031143 pseudopodium(GO:0031143)
0.0 1.0 GO:0009986 cell surface(GO:0009986)
0.0 0.2 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.3 GO:0051233 spindle midzone(GO:0051233)
0.0 0.6 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 2.2 GO:0001726 ruffle(GO:0001726)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 23.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.8 3.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.6 2.3 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.4 1.5 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.4 6.1 GO:0046625 sphingolipid binding(GO:0046625)
0.3 1.0 GO:0016748 succinyltransferase activity(GO:0016748)
0.3 1.0 GO:0005110 frizzled-2 binding(GO:0005110)
0.3 1.2 GO:0008061 chitin binding(GO:0008061)
0.3 3.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.2 1.9 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.2 0.5 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.1 3.7 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 0.7 GO:0045545 syndecan binding(GO:0045545)
0.1 1.3 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 2.3 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 5.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 3.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 0.3 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 2.1 GO:0031402 sodium ion binding(GO:0031402)
0.1 1.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.7 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 0.4 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 0.3 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.1 0.5 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 0.7 GO:0032564 dATP binding(GO:0032564)
0.1 0.5 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.4 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.9 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 1.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 0.2 GO:0046790 virion binding(GO:0046790)
0.1 0.6 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 0.2 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 2.9 GO:0030507 spectrin binding(GO:0030507)
0.0 6.3 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 0.2 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.9 GO:0031690 adrenergic receptor binding(GO:0031690)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.6 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 4.5 GO:0046332 SMAD binding(GO:0046332)
0.0 3.9 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.8 GO:0016208 AMP binding(GO:0016208)
0.0 0.8 GO:0043422 protein kinase B binding(GO:0043422)
0.0 3.2 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 1.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.5 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.7 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.6 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.3 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.3 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 1.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.2 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.4 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.1 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 21.3 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 5.8 PID_ARF6_PATHWAY Arf6 signaling events
0.1 2.3 PID_IL5_PATHWAY IL5-mediated signaling events
0.1 0.7 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.1 2.5 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.1 1.2 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 0.9 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.1 4.8 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.1 3.0 PID_ATR_PATHWAY ATR signaling pathway
0.1 2.7 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 7.4 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 3.3 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 1.0 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 1.5 PID_IFNG_PATHWAY IFN-gamma pathway
0.0 0.9 PID_ENDOTHELIN_PATHWAY Endothelins
0.0 0.5 PID_AVB3_OPN_PATHWAY Osteopontin-mediated events
0.0 1.3 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 0.4 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.5 PID_AR_PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.2 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 2.3 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.2 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 1.3 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.1 1.4 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 2.3 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.1 3.2 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 2.8 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 0.8 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.1 4.8 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.1 5.4 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.0 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.7 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.2 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.4 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.3 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.6 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.9 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.7 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.1 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.3 REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.4 REACTOME_ENOS_ACTIVATION_AND_REGULATION Genes involved in eNOS activation and regulation
0.0 0.6 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.7 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.2 REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 1.1 REACTOME_SIGNALING_BY_EGFR_IN_CANCER Genes involved in Signaling by EGFR in Cancer