Motif ID: Creb3l2

Z-value: 0.668


Transcription factors associated with Creb3l2:

Gene SymbolEntrez IDGene Name
Creb3l2 ENSMUSG00000038648.5 Creb3l2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Creb3l2mm10_v2_chr6_-_37442095_37442154-0.211.9e-01Click!


Activity profile for motif Creb3l2.

activity profile for motif Creb3l2


Sorted Z-values histogram for motif Creb3l2

Sorted Z-values for motif Creb3l2



Network of associatons between targets according to the STRING database.



First level regulatory network of Creb3l2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_135251209 5.150 ENSMUST00000062572.2
Fzd9
frizzled homolog 9 (Drosophila)
chr7_+_19094594 4.988 ENSMUST00000049454.5
Six5
sine oculis-related homeobox 5
chr7_-_25250720 4.438 ENSMUST00000116343.2
ENSMUST00000045847.8
Erf

Ets2 repressor factor

chr2_-_105399286 4.381 ENSMUST00000006128.6
Rcn1
reticulocalbin 1
chr9_-_43239816 4.030 ENSMUST00000034512.5
Oaf
OAF homolog (Drosophila)
chr15_+_79516396 3.514 ENSMUST00000010974.7
Kdelr3
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr3_-_20155069 3.263 ENSMUST00000184552.1
ENSMUST00000178328.1
Gyg

glycogenin

chr2_+_84840612 3.142 ENSMUST00000111625.1
Slc43a1
solute carrier family 43, member 1
chr11_-_94653964 3.103 ENSMUST00000039949.4
Eme1
essential meiotic endonuclease 1 homolog 1 (S. pombe)
chr6_+_56832059 2.874 ENSMUST00000031795.7
Fkbp9
FK506 binding protein 9
chr10_+_13090788 2.773 ENSMUST00000121646.1
ENSMUST00000121325.1
ENSMUST00000121766.1
Plagl1


pleiomorphic adenoma gene-like 1


chr15_+_34238026 2.659 ENSMUST00000022867.3
Laptm4b
lysosomal-associated protein transmembrane 4B
chr16_-_78376758 2.431 ENSMUST00000023570.7
Btg3
B cell translocation gene 3
chr11_+_100415697 2.381 ENSMUST00000001595.3
Fkbp10
FK506 binding protein 10
chr5_-_30945393 2.191 ENSMUST00000031051.6
Cgref1
cell growth regulator with EF hand domain 1
chrX_+_50841434 2.108 ENSMUST00000114887.2
2610018G03Rik
RIKEN cDNA 2610018G03 gene
chr8_+_14911663 2.039 ENSMUST00000084207.5
ENSMUST00000161162.1
ENSMUST00000110800.2
Arhgef10


Rho guanine nucleotide exchange factor (GEF) 10


chr11_+_100415722 2.033 ENSMUST00000107400.2
Fkbp10
FK506 binding protein 10
chr10_+_20148920 2.002 ENSMUST00000116259.3
Map7
microtubule-associated protein 7
chr19_-_4201591 1.986 ENSMUST00000025740.6
Rad9a
RAD9 homolog A
chr12_+_17544873 1.789 ENSMUST00000171737.1
Odc1
ornithine decarboxylase, structural 1
chr7_+_79392305 1.764 ENSMUST00000117227.1
ENSMUST00000118959.1
ENSMUST00000036865.6
Fanci


Fanconi anemia, complementation group I


chr13_-_119408985 1.690 ENSMUST00000099149.3
ENSMUST00000069902.6
ENSMUST00000109204.1
Nnt


nicotinamide nucleotide transhydrogenase


chr19_+_34922351 1.673 ENSMUST00000087341.5
Kif20b
kinesin family member 20B
chr3_+_104638658 1.645 ENSMUST00000046212.1
Slc16a1
solute carrier family 16 (monocarboxylic acid transporters), member 1
chr10_+_128909866 1.537 ENSMUST00000026407.7
Cd63
CD63 antigen
chr6_-_83317589 1.507 ENSMUST00000005810.6
Mthfd2
methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase
chr2_+_150786735 1.499 ENSMUST00000045441.7
Pygb
brain glycogen phosphorylase
chr5_+_63812447 1.480 ENSMUST00000081747.3
0610040J01Rik
RIKEN cDNA 0610040J01 gene
chr15_-_34495180 1.307 ENSMUST00000022946.5
Hrsp12
heat-responsive protein 12
chr7_-_127260677 1.274 ENSMUST00000035276.4
Dctpp1
dCTP pyrophosphatase 1
chr18_+_75367529 1.232 ENSMUST00000026999.3
Smad7
SMAD family member 7
chr10_-_34418465 1.226 ENSMUST00000099973.3
ENSMUST00000105512.1
ENSMUST00000047885.7
Nt5dc1


5'-nucleotidase domain containing 1


chr10_+_61648552 1.215 ENSMUST00000020286.6
Ppa1
pyrophosphatase (inorganic) 1
chr2_-_92370999 1.193 ENSMUST00000176810.1
ENSMUST00000090582.4
Gyltl1b

glycosyltransferase-like 1B

chr4_-_108406676 1.189 ENSMUST00000184609.1
Gpx7
glutathione peroxidase 7
chr7_-_80115294 1.183 ENSMUST00000107384.3
Idh2
isocitrate dehydrogenase 2 (NADP+), mitochondrial
chr19_+_46056539 1.163 ENSMUST00000111899.1
ENSMUST00000099392.3
ENSMUST00000062322.4
Pprc1


peroxisome proliferative activated receptor, gamma, coactivator-related 1


chr6_-_101377342 1.160 ENSMUST00000151175.1
Pdzrn3
PDZ domain containing RING finger 3
chr5_+_31054821 1.035 ENSMUST00000174367.1
ENSMUST00000170329.1
ENSMUST00000031049.6
Cad


carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase


chr11_+_94653767 1.014 ENSMUST00000025278.7
Mrpl27
mitochondrial ribosomal protein L27
chr5_+_31054766 0.999 ENSMUST00000013773.5
ENSMUST00000114646.1
Cad

carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase

chrX_+_153139941 0.991 ENSMUST00000039720.4
ENSMUST00000144175.2
Rragb

Ras-related GTP binding B

chr18_+_53176345 0.982 ENSMUST00000037850.5
Snx2
sorting nexin 2
chr3_+_144570409 0.976 ENSMUST00000082437.3
Sep15
selenoprotein
chr3_-_101604580 0.963 ENSMUST00000036493.6
Atp1a1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr3_+_153973436 0.922 ENSMUST00000089948.5
Slc44a5
solute carrier family 44, member 5
chr11_+_69935796 0.918 ENSMUST00000018698.5
Ybx2
Y box protein 2
chr6_-_13871477 0.900 ENSMUST00000139231.1
2610001J05Rik
RIKEN cDNA 2610001J05 gene
chr2_-_92371039 0.876 ENSMUST00000068586.6
Gyltl1b
glycosyltransferase-like 1B
chr19_+_53903351 0.872 ENSMUST00000025931.6
ENSMUST00000165617.1
Pdcd4

programmed cell death 4

chr3_+_96697100 0.853 ENSMUST00000107077.3
Pias3
protein inhibitor of activated STAT 3
chr10_-_20725023 0.841 ENSMUST00000020165.7
Pde7b
phosphodiesterase 7B
chr7_+_105640448 0.818 ENSMUST00000058333.3
Timm10b
translocase of inner mitochondrial membrane 10B
chr17_+_45563928 0.802 ENSMUST00000041353.6
Slc35b2
solute carrier family 35, member B2
chr6_-_13871459 0.798 ENSMUST00000155856.1
2610001J05Rik
RIKEN cDNA 2610001J05 gene
chr11_+_70000578 0.776 ENSMUST00000019362.8
Dvl2
dishevelled 2, dsh homolog (Drosophila)
chr7_+_105640522 0.769 ENSMUST00000106785.1
ENSMUST00000106786.1
ENSMUST00000106780.1
ENSMUST00000106784.1
Timm10b



translocase of inner mitochondrial membrane 10B



chr14_-_26638183 0.757 ENSMUST00000166902.1
4930570N19Rik
RIKEN cDNA 4930570N19 gene
chr10_+_20148457 0.755 ENSMUST00000020173.8
Map7
microtubule-associated protein 7
chr11_-_97782409 0.751 ENSMUST00000103146.4
Rpl23
ribosomal protein L23
chr13_+_55321991 0.720 ENSMUST00000021942.6
Prelid1
PRELI domain containing 1
chr5_-_30105359 0.705 ENSMUST00000127749.3
3110082J24Rik
RIKEN cDNA 3110082J24 gene
chr5_-_137610626 0.704 ENSMUST00000142675.1
Pcolce
procollagen C-endopeptidase enhancer protein
chr3_+_96697076 0.629 ENSMUST00000162778.2
ENSMUST00000064900.9
Pias3

protein inhibitor of activated STAT 3

chr2_-_92370968 0.626 ENSMUST00000176774.1
Gyltl1b
glycosyltransferase-like 1B
chr5_+_143403819 0.619 ENSMUST00000110731.2
Kdelr2
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr13_+_73330982 0.588 ENSMUST00000022098.8
Mrpl36
mitochondrial ribosomal protein L36
chr15_-_97767644 0.569 ENSMUST00000128775.2
ENSMUST00000134885.2
Rapgef3

Rap guanine nucleotide exchange factor (GEF) 3

chrX_-_8145679 0.564 ENSMUST00000115619.1
ENSMUST00000115617.3
ENSMUST00000040010.3
Rbm3


RNA binding motif protein 3


chr14_-_55643251 0.561 ENSMUST00000120041.1
ENSMUST00000121937.1
ENSMUST00000133707.1
ENSMUST00000002391.8
ENSMUST00000121791.1
Tm9sf1




transmembrane 9 superfamily member 1




chr11_-_97782377 0.550 ENSMUST00000128801.1
Rpl23
ribosomal protein L23
chr5_+_137641334 0.546 ENSMUST00000177466.1
ENSMUST00000166099.2
Sap25

sin3 associated polypeptide

chr3_-_37724321 0.510 ENSMUST00000108105.1
ENSMUST00000079755.4
ENSMUST00000099128.1
Gm5148


predicted gene 5148


chr17_+_35424842 0.504 ENSMUST00000174699.1
H2-Q6
histocompatibility 2, Q region locus 6
chr2_+_69861562 0.503 ENSMUST00000090852.4
ENSMUST00000166411.1
Ssb

Sjogren syndrome antigen B

chr4_+_128654686 0.494 ENSMUST00000030588.6
ENSMUST00000136377.1
Phc2

polyhomeotic-like 2 (Drosophila)

chr2_+_130274424 0.488 ENSMUST00000103198.4
Nop56
NOP56 ribonucleoprotein
chr5_+_30105161 0.447 ENSMUST00000058045.4
Gareml
GRB2 associated, regulator of MAPK1-like
chr14_-_55643523 0.432 ENSMUST00000132338.1
Tm9sf1
transmembrane 9 superfamily member 1
chr16_-_96127604 0.426 ENSMUST00000133885.1
ENSMUST00000050884.7
Hmgn1

high mobility group nucleosomal binding domain 1

chr14_-_55643800 0.424 ENSMUST00000122358.1
Tm9sf1
transmembrane 9 superfamily member 1
chr5_-_31154152 0.413 ENSMUST00000114632.1
ENSMUST00000114631.2
ENSMUST00000067186.6
ENSMUST00000137165.1
ENSMUST00000131391.1
ENSMUST00000141823.1
ENSMUST00000154241.1
Mpv17






MpV17 mitochondrial inner membrane protein






chr2_+_164833841 0.413 ENSMUST00000152721.1
Ctsa
cathepsin A
chr17_+_29032664 0.405 ENSMUST00000130216.1
Srsf3
serine/arginine-rich splicing factor 3
chr11_-_96075581 0.402 ENSMUST00000107686.1
ENSMUST00000107684.1
Atp5g1

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9)

chr2_+_164833781 0.395 ENSMUST00000143780.1
Ctsa
cathepsin A
chr5_+_129941949 0.381 ENSMUST00000051758.7
ENSMUST00000073945.4
Vkorc1l1

vitamin K epoxide reductase complex, subunit 1-like 1

chr15_+_34495302 0.375 ENSMUST00000052290.7
ENSMUST00000079028.5
Pop1

processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae)

chr7_+_97696634 0.357 ENSMUST00000026506.4
Clns1a
chloride channel, nucleotide-sensitive, 1A
chr2_-_32694120 0.357 ENSMUST00000028148.4
Fpgs
folylpolyglutamyl synthetase
chrX_+_8271133 0.353 ENSMUST00000127103.1
ENSMUST00000115591.1
Slc38a5

solute carrier family 38, member 5

chr2_+_132846638 0.352 ENSMUST00000028835.6
ENSMUST00000110122.3
Crls1

cardiolipin synthase 1

chr4_-_119422355 0.329 ENSMUST00000106316.1
ENSMUST00000030385.6
Ppcs

phosphopantothenoylcysteine synthetase

chr1_+_63176818 0.329 ENSMUST00000129339.1
Eef1b2
eukaryotic translation elongation factor 1 beta 2
chr14_-_55643720 0.318 ENSMUST00000138085.1
Tm9sf1
transmembrane 9 superfamily member 1
chr11_+_51584757 0.301 ENSMUST00000167797.1
ENSMUST00000020625.6
Phykpl

5-phosphohydroxy-L-lysine phospholyase

chr17_-_24163668 0.298 ENSMUST00000040735.5
Amdhd2
amidohydrolase domain containing 2
chr17_-_26939464 0.295 ENSMUST00000025027.8
ENSMUST00000114935.1
Cuta

cutA divalent cation tolerance homolog (E. coli)

chr5_+_108268897 0.295 ENSMUST00000031190.4
Dr1
down-regulator of transcription 1
chr1_-_163725123 0.289 ENSMUST00000159679.1
Mettl11b
methyltransferase like 11B
chr18_-_40219324 0.288 ENSMUST00000025364.4
Yipf5
Yip1 domain family, member 5
chr2_+_130274437 0.261 ENSMUST00000141872.1
Nop56
NOP56 ribonucleoprotein
chr2_+_144368961 0.257 ENSMUST00000028911.8
ENSMUST00000147747.1
ENSMUST00000183618.1
Csrp2bp

Pet117
cysteine and glycine-rich protein 2 binding protein

PET117 homolog (S. cerevisiae)
chr11_-_5099036 0.257 ENSMUST00000102930.3
Ewsr1
Ewing sarcoma breakpoint region 1
chr10_-_62486772 0.245 ENSMUST00000105447.3
Vps26a
vacuolar protein sorting 26 homolog A (yeast)
chr17_+_71183545 0.236 ENSMUST00000156570.1
Lpin2
lipin 2
chr17_-_86145139 0.235 ENSMUST00000095187.3
Srbd1
S1 RNA binding domain 1
chr11_+_20201406 0.232 ENSMUST00000020358.5
ENSMUST00000109602.1
ENSMUST00000109601.1
Rab1


RAB1, member RAS oncogene family


chr17_-_56074932 0.229 ENSMUST00000019722.5
Ubxn6
UBX domain protein 6
chr11_-_96075655 0.224 ENSMUST00000090541.5
Atp5g1
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9)
chr17_-_12769605 0.216 ENSMUST00000024599.7
Igf2r
insulin-like growth factor 2 receptor
chr13_-_24206281 0.210 ENSMUST00000123076.1
Lrrc16a
leucine rich repeat containing 16A
chr17_+_35424870 0.204 ENSMUST00000113879.3
H2-Q6
histocompatibility 2, Q region locus 6
chr10_+_78574492 0.202 ENSMUST00000105384.3
Ilvbl
ilvB (bacterial acetolactate synthase)-like
chr7_-_105640308 0.199 ENSMUST00000133519.1
ENSMUST00000084782.2
ENSMUST00000131446.1
Arfip2


ADP-ribosylation factor interacting protein 2


chr13_+_90089705 0.193 ENSMUST00000012566.8
Tmem167
transmembrane protein 167
chr8_+_111033890 0.185 ENSMUST00000034441.7
Aars
alanyl-tRNA synthetase
chr9_-_106887000 0.180 ENSMUST00000055843.7
Rbm15b
RNA binding motif protein 15B
chr10_+_61680302 0.165 ENSMUST00000020285.8
Sar1a
SAR1 gene homolog A (S. cerevisiae)
chr11_-_5099223 0.152 ENSMUST00000079949.6
Ewsr1
Ewing sarcoma breakpoint region 1
chr16_-_5049882 0.146 ENSMUST00000023189.7
ENSMUST00000115844.1
Glyr1

glyoxylate reductase 1 homolog (Arabidopsis)

chr11_-_120572822 0.146 ENSMUST00000168360.1
P4hb
prolyl 4-hydroxylase, beta polypeptide
chr3_+_40540751 0.143 ENSMUST00000091186.3
Intu
inturned planar cell polarity effector homolog (Drosophila)
chr2_+_70661556 0.142 ENSMUST00000112201.1
ENSMUST00000028509.4
ENSMUST00000133432.1
ENSMUST00000112205.1
Gorasp2



golgi reassembly stacking protein 2



chr14_+_26638237 0.134 ENSMUST00000112318.3
Arf4
ADP-ribosylation factor 4
chr7_-_27166413 0.117 ENSMUST00000108382.1
Egln2
EGL nine homolog 2 (C. elegans)
chr14_-_70443442 0.113 ENSMUST00000000793.5
Polr3d
polymerase (RNA) III (DNA directed) polypeptide D
chr8_-_94601720 0.107 ENSMUST00000034226.6
Fam192a
family with sequence similarity 192, member A
chr9_-_25151772 0.107 ENSMUST00000008573.7
Herpud2
HERPUD family member 2
chr4_+_155993305 0.097 ENSMUST00000105578.1
Sdf4
stromal cell derived factor 4
chr3_-_108226598 0.095 ENSMUST00000029486.7
ENSMUST00000156371.1
ENSMUST00000141387.1
Sypl2


synaptophysin-like 2


chr13_-_55321928 0.094 ENSMUST00000035242.7
Rab24
RAB24, member RAS oncogene family
chr11_+_5099406 0.093 ENSMUST00000134267.1
ENSMUST00000036320.5
ENSMUST00000150632.1
Rhbdd3


rhomboid domain containing 3


chr5_-_35679416 0.082 ENSMUST00000114233.2
Htra3
HtrA serine peptidase 3
chr11_-_5099053 0.073 ENSMUST00000093365.5
ENSMUST00000073308.4
Ewsr1

Ewing sarcoma breakpoint region 1

chr3_-_27710413 0.058 ENSMUST00000046157.4
Fndc3b
fibronectin type III domain containing 3B
chr19_+_6975048 0.052 ENSMUST00000070850.6
Ppp1r14b
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr2_+_69861638 0.046 ENSMUST00000112260.1
Ssb
Sjogren syndrome antigen B
chr1_+_171345684 0.043 ENSMUST00000006579.4
Pfdn2
prefoldin 2
chr2_+_130424321 0.041 ENSMUST00000128994.1
ENSMUST00000028900.9
Vps16

vacuolar protein sorting 16 (yeast)

chr5_+_30869579 0.033 ENSMUST00000046349.7
Tmem214
transmembrane protein 214
chr17_-_56276750 0.024 ENSMUST00000058136.8
Ticam1
toll-like receptor adaptor molecule 1
chr11_+_44518959 0.009 ENSMUST00000019333.3
Rnf145
ring finger protein 145
chr4_+_130047914 0.006 ENSMUST00000142293.1
Col16a1
collagen, type XVI, alpha 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.2 GO:1990523 bone regeneration(GO:1990523)
0.9 4.4 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.6 3.1 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.6 1.8 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.6 4.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.6 1.7 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.5 2.0 GO:0006526 arginine biosynthetic process(GO:0006526)
0.4 1.2 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.4 1.2 GO:0006097 glyoxylate cycle(GO:0006097) negative regulation of glial cell migration(GO:1903976)
0.4 5.0 GO:0014842 regulation of skeletal muscle satellite cell proliferation(GO:0014842)
0.3 1.3 GO:0006244 pyrimidine nucleotide catabolic process(GO:0006244) pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.3 1.5 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.3 0.9 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.3 1.3 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.2 1.0 GO:1903416 response to glycoside(GO:1903416)
0.2 2.0 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.2 2.8 GO:0033327 Leydig cell differentiation(GO:0033327)
0.2 1.6 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.2 0.8 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.2 4.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.4 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.1 0.5 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1 0.8 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.1 0.4 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 0.4 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1 1.5 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 3.5 GO:0015804 neutral amino acid transport(GO:0015804)
0.1 0.8 GO:0051503 adenine nucleotide transport(GO:0051503)
0.1 1.0 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.1 0.7 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.1 1.0 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 1.8 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 1.5 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1 0.3 GO:1904451 regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453)
0.1 0.4 GO:0016078 tRNA catabolic process(GO:0016078)
0.1 0.2 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 2.0 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.3 GO:1901072 glucosamine-containing compound catabolic process(GO:1901072)
0.0 0.4 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.4 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.2 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 1.7 GO:0006739 NADP metabolic process(GO:0006739)
0.0 2.9 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 2.8 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.4 GO:0045794 negative regulation of cell volume(GO:0045794)
0.0 0.3 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.1 GO:0070625 zymogen granule exocytosis(GO:0070625)
0.0 0.2 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 0.6 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 0.3 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 1.1 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.9 GO:0048255 mRNA stabilization(GO:0048255)
0.0 0.7 GO:0000154 rRNA modification(GO:0000154)
0.0 1.2 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.7 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.6 GO:0009409 response to cold(GO:0009409)
0.0 0.3 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.1 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 4.4 GO:0043010 camera-type eye development(GO:0043010)
0.0 1.6 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.2 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.4 1.5 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.3 2.0 GO:0030896 checkpoint clamp complex(GO:0030896)
0.3 1.0 GO:0030905 retromer, tubulation complex(GO:0030905)
0.3 1.6 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.2 5.2 GO:0031527 filopodium membrane(GO:0031527)
0.2 1.0 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 1.8 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 1.0 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 1.7 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 0.7 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 1.2 GO:0016342 catenin complex(GO:0016342)
0.1 0.4 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.1 0.3 GO:0097574 lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795)
0.1 0.4 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 0.2 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 0.7 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.6 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 1.6 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.5 GO:0035102 PRC1 complex(GO:0035102)
0.0 1.9 GO:0015934 large ribosomal subunit(GO:0015934)
0.0 2.0 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.8 GO:0016235 aggresome(GO:0016235)
0.0 0.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.1 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.9 GO:0005844 polysome(GO:0005844)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 1.2 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.6 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.7 GO:0031970 organelle envelope lumen(GO:0031970)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.5 2.0 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.5 1.5 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.5 2.0 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.4 1.2 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.4 3.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.4 1.5 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.4 7.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.4 3.3 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.3 1.2 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.3 1.2 GO:0004096 catalase activity(GO:0004096)
0.3 0.8 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.2 1.0 GO:1990460 leptin receptor binding(GO:1990460)
0.2 0.7 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.2 1.6 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.2 5.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 1.3 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.2 1.3 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 1.2 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072) activin binding(GO:0048185)
0.1 0.4 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.1 1.0 GO:1990239 steroid hormone binding(GO:1990239)
0.1 0.8 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 3.5 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 0.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 1.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 1.0 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.6 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.2 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 1.8 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 0.7 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 0.7 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 1.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 1.5 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 1.8 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.3 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.7 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.4 GO:0048038 quinone binding(GO:0048038)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 2.0 GO:0019894 kinesin binding(GO:0019894)
0.0 1.5 GO:0051287 NAD binding(GO:0051287)
0.0 0.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.9 GO:0045182 translation regulator activity(GO:0045182)
0.0 4.4 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.7 GO:0016504 peptidase activator activity(GO:0016504)
0.0 2.8 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.4 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.7 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 6.6 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.3 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.8 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 5.0 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.2 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.1 1.5 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.1 3.8 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 0.8 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.0 1.2 PID_ALK1_PATHWAY ALK1 signaling events
0.0 3.5 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 2.0 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.5 PID_BARD1_PATHWAY BARD1 signaling events
0.0 1.0 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.0 1.9 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 1.3 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 0.2 ST_G_ALPHA_S_PATHWAY G alpha s Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 2.7 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 3.5 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 2.0 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.1 3.6 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 1.3 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.5 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 5.2 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 3.1 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 0.9 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 1.4 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 2.0 REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS Genes involved in Activation of ATR in response to replication stress
0.0 1.2 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.0 0.6 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 1.0 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.3 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.8 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.2 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 1.5 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.4 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.9 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.8 REACTOME_G_ALPHA_S_SIGNALLING_EVENTS Genes involved in G alpha (s) signalling events
0.0 1.3 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation