Motif ID: Hoxb2_Dlx2

Z-value: 1.009

Transcription factors associated with Hoxb2_Dlx2:

Gene SymbolEntrez IDGene Name
Dlx2 ENSMUSG00000023391.7 Dlx2
Hoxb2 ENSMUSG00000075588.5 Hoxb2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Dlx2mm10_v2_chr2_-_71546745_715467580.883.2e-14Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxb2_Dlx2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_71528657 15.079 ENSMUST00000126400.1
Dlx1
distal-less homeobox 1
chr2_-_71546745 10.236 ENSMUST00000024159.6
Dlx2
distal-less homeobox 2
chr18_-_80986578 8.425 ENSMUST00000057950.7
Sall3
sal-like 3 (Drosophila)
chr6_+_8948608 8.305 ENSMUST00000160300.1
Nxph1
neurexophilin 1
chrX_-_60893430 8.124 ENSMUST00000135107.2
Sox3
SRY-box containing gene 3
chr2_+_73271925 7.515 ENSMUST00000090813.5
Sp9
trans-acting transcription factor 9
chr19_-_59170978 7.468 ENSMUST00000172821.2
Vax1
ventral anterior homeobox containing gene 1
chr3_-_88410295 7.333 ENSMUST00000056370.7
Pmf1
polyamine-modulated factor 1
chr5_+_139543889 7.323 ENSMUST00000174792.1
ENSMUST00000031523.8
Uncx

UNC homeobox

chr14_-_118052235 7.160 ENSMUST00000022725.2
Dct
dopachrome tautomerase
chr15_-_8710734 7.150 ENSMUST00000005493.7
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr14_-_48665098 6.570 ENSMUST00000118578.1
Otx2
orthodenticle homolog 2 (Drosophila)
chr2_+_20737306 6.557 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4

enhancer trap locus 4

chr7_+_144838590 6.063 ENSMUST00000105898.1
Fgf3
fibroblast growth factor 3
chr15_-_8710409 5.993 ENSMUST00000157065.1
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr3_+_122419772 5.627 ENSMUST00000029766.4
Bcar3
breast cancer anti-estrogen resistance 3
chr3_+_159839729 5.513 ENSMUST00000068952.5
Wls
wntless homolog (Drosophila)
chr3_-_116253467 5.106 ENSMUST00000090473.5
Gpr88
G-protein coupled receptor 88
chr2_+_22622183 4.562 ENSMUST00000028123.3
Gad2
glutamic acid decarboxylase 2
chr4_-_14621805 4.420 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr12_+_38780284 4.265 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
Etv1


ets variant gene 1


chr12_+_38783503 4.253 ENSMUST00000159334.1
Etv1
ets variant gene 1
chr2_+_25372315 3.991 ENSMUST00000028329.6
ENSMUST00000114293.2
ENSMUST00000100323.2
Sapcd2


suppressor APC domain containing 2


chr15_+_25773985 3.924 ENSMUST00000125667.1
Myo10
myosin X
chr4_+_136143497 3.854 ENSMUST00000008016.2
Id3
inhibitor of DNA binding 3
chr16_+_45094036 3.807 ENSMUST00000061050.5
Ccdc80
coiled-coil domain containing 80
chr12_+_38780817 3.706 ENSMUST00000160856.1
Etv1
ets variant gene 1
chr3_+_134236483 3.664 ENSMUST00000181904.1
ENSMUST00000053048.9
Cxxc4

CXXC finger 4

chr13_-_102906046 3.655 ENSMUST00000171791.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr6_+_4755327 3.645 ENSMUST00000176551.1
Peg10
paternally expressed 10
chr7_-_66427469 3.579 ENSMUST00000015278.7
Aldh1a3
aldehyde dehydrogenase family 1, subfamily A3
chr2_-_72986716 3.329 ENSMUST00000112062.1
Gm11084
predicted gene 11084
chr6_-_23248264 3.268 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr4_-_14621494 3.179 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chr13_-_102905740 3.141 ENSMUST00000167462.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr17_-_70853482 3.137 ENSMUST00000118283.1
Tgif1
TGFB-induced factor homeobox 1
chr19_+_43612299 2.866 ENSMUST00000057178.9
Nkx2-3
NK2 homeobox 3
chr6_-_124779686 2.773 ENSMUST00000147669.1
ENSMUST00000128697.1
ENSMUST00000032218.3
ENSMUST00000112475.2
Lrrc23



leucine rich repeat containing 23



chr4_-_14621669 2.701 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr4_-_43499608 2.654 ENSMUST00000136005.1
ENSMUST00000054538.6
Arhgef39

Rho guanine nucleotide exchange factor (GEF) 39

chr8_-_61902669 2.561 ENSMUST00000121785.1
ENSMUST00000034057.7
Palld

palladin, cytoskeletal associated protein

chr14_-_70642268 2.543 ENSMUST00000022697.5
Fgf17
fibroblast growth factor 17
chr7_-_116198487 2.501 ENSMUST00000181981.1
Plekha7
pleckstrin homology domain containing, family A member 7
chr10_-_45470201 2.488 ENSMUST00000079390.6
Lin28b
lin-28 homolog B (C. elegans)
chr5_-_98566762 2.475 ENSMUST00000086912.4
1700010H22Rik
RIKEN cDNA 1700010H22 gene
chr2_+_52038005 2.470 ENSMUST00000065927.5
Tnfaip6
tumor necrosis factor alpha induced protein 6
chr9_-_79977782 2.431 ENSMUST00000093811.4
Filip1
filamin A interacting protein 1
chr2_+_83724397 2.337 ENSMUST00000028499.4
ENSMUST00000141725.1
ENSMUST00000111740.2
Itgav


integrin alpha V


chr13_+_23575753 2.214 ENSMUST00000105105.1
Hist1h3d
histone cluster 1, H3d
chr15_-_37458523 2.140 ENSMUST00000116445.2
Ncald
neurocalcin delta
chr1_-_152625212 2.117 ENSMUST00000027760.7
Rgl1
ral guanine nucleotide dissociation stimulator,-like 1
chr2_-_166155272 2.109 ENSMUST00000088086.3
Sulf2
sulfatase 2
chr3_-_154328634 2.089 ENSMUST00000167744.1
Lhx8
LIM homeobox protein 8
chr4_+_62583568 2.033 ENSMUST00000098031.3
Rgs3
regulator of G-protein signaling 3
chr13_-_56252163 2.020 ENSMUST00000058475.4
Neurog1
neurogenin 1
chr3_-_154330543 2.008 ENSMUST00000184966.1
ENSMUST00000177846.2
Lhx8

LIM homeobox protein 8

chr3_-_141982224 1.929 ENSMUST00000029948.8
Bmpr1b
bone morphogenetic protein receptor, type 1B
chr5_-_87482258 1.898 ENSMUST00000079811.6
ENSMUST00000144144.1
Ugt2a1

UDP glucuronosyltransferase 2 family, polypeptide A1

chr15_+_34238026 1.887 ENSMUST00000022867.3
Laptm4b
lysosomal-associated protein transmembrane 4B
chr8_+_23411490 1.877 ENSMUST00000033952.7
Sfrp1
secreted frizzled-related protein 1
chr4_+_8690399 1.875 ENSMUST00000127476.1
Chd7
chromodomain helicase DNA binding protein 7
chr12_+_38783455 1.873 ENSMUST00000161980.1
ENSMUST00000160701.1
Etv1

ets variant gene 1

chr2_-_168767136 1.828 ENSMUST00000029061.5
ENSMUST00000103074.1
Sall4

sal-like 4 (Drosophila)

chr17_+_34039437 1.824 ENSMUST00000131134.1
ENSMUST00000087497.4
ENSMUST00000114255.1
ENSMUST00000114252.1
Col11a2



collagen, type XI, alpha 2



chr2_+_152754156 1.811 ENSMUST00000010020.5
Cox4i2
cytochrome c oxidase subunit IV isoform 2
chr2_-_166155624 1.792 ENSMUST00000109249.2
Sulf2
sulfatase 2
chr5_-_53707532 1.783 ENSMUST00000031093.3
Cckar
cholecystokinin A receptor
chr5_+_15516489 1.746 ENSMUST00000178227.1
Gm21847
predicted gene, 21847
chr3_-_157925056 1.732 ENSMUST00000118539.1
Cth
cystathionase (cystathionine gamma-lyase)
chr14_-_48662740 1.714 ENSMUST00000122009.1
Otx2
orthodenticle homolog 2 (Drosophila)
chr9_-_96437434 1.709 ENSMUST00000070500.2
BC043934
cDNA sequence BC043934
chr13_-_58354862 1.701 ENSMUST00000043605.5
Kif27
kinesin family member 27
chr1_-_72284248 1.700 ENSMUST00000097698.4
ENSMUST00000027381.6
Pecr

peroxisomal trans-2-enoyl-CoA reductase

chr3_-_79841729 1.693 ENSMUST00000168038.1
Tmem144
transmembrane protein 144
chr4_-_109665249 1.680 ENSMUST00000063531.4
Cdkn2c
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr16_+_45093611 1.659 ENSMUST00000099498.2
Ccdc80
coiled-coil domain containing 80
chr13_-_53473074 1.625 ENSMUST00000021922.8
Msx2
msh homeobox 2
chr15_-_79285502 1.609 ENSMUST00000165408.1
Baiap2l2
BAI1-associated protein 2-like 2
chr10_+_26772477 1.602 ENSMUST00000039557.7
Arhgap18
Rho GTPase activating protein 18
chr18_+_4920509 1.589 ENSMUST00000126977.1
Svil
supervillin
chr2_-_168767029 1.572 ENSMUST00000075044.3
Sall4
sal-like 4 (Drosophila)
chrX_-_102157065 1.569 ENSMUST00000056904.2
Ercc6l
excision repair cross-complementing rodent repair deficiency complementation group 6 like
chr12_+_38781093 1.536 ENSMUST00000161513.1
Etv1
ets variant gene 1
chrX_+_56779437 1.488 ENSMUST00000114773.3
Fhl1
four and a half LIM domains 1
chr7_-_115824699 1.462 ENSMUST00000169129.1
Sox6
SRY-box containing gene 6
chr13_+_51408618 1.447 ENSMUST00000087978.3
S1pr3
sphingosine-1-phosphate receptor 3
chr7_-_5014645 1.431 ENSMUST00000165320.1
Fiz1
Flt3 interacting zinc finger protein 1
chr7_-_100656953 1.428 ENSMUST00000107046.1
ENSMUST00000107045.1
ENSMUST00000139708.1
Plekhb1


pleckstrin homology domain containing, family B (evectins) member 1


chr12_-_40037387 1.379 ENSMUST00000146905.1
Arl4a
ADP-ribosylation factor-like 4A
chr3_+_133338936 1.372 ENSMUST00000150386.1
ENSMUST00000125858.1
Ppa2

pyrophosphatase (inorganic) 2

chr3_+_66219909 1.313 ENSMUST00000029421.5
Ptx3
pentraxin related gene
chr3_-_66296807 1.301 ENSMUST00000029419.7
Veph1
ventricular zone expressed PH domain-containing 1
chr18_+_82914632 1.298 ENSMUST00000071233.6
Zfp516
zinc finger protein 516
chr3_+_68572245 1.297 ENSMUST00000170788.2
Schip1
schwannomin interacting protein 1
chr15_-_71954395 1.290 ENSMUST00000159410.1
Col22a1
collagen, type XXII, alpha 1
chr7_-_116038734 1.223 ENSMUST00000166877.1
Sox6
SRY-box containing gene 6
chr4_+_3940747 1.206 ENSMUST00000119403.1
Chchd7
coiled-coil-helix-coiled-coil-helix domain containing 7
chr10_-_80421847 1.202 ENSMUST00000156244.1
Tcf3
transcription factor 3
chr9_-_71163224 1.201 ENSMUST00000074465.2
Aqp9
aquaporin 9
chr5_-_134747241 1.192 ENSMUST00000015138.9
Eln
elastin
chr18_+_4993795 1.188 ENSMUST00000153016.1
Svil
supervillin
chr3_+_122044428 1.162 ENSMUST00000013995.8
Abca4
ATP-binding cassette, sub-family A (ABC1), member 4
chr6_-_147264124 1.142 ENSMUST00000052296.6
Pthlh
parathyroid hormone-like peptide
chr3_-_55055038 1.138 ENSMUST00000029368.2
Ccna1
cyclin A1
chrX_+_56779699 1.130 ENSMUST00000114772.2
ENSMUST00000114768.3
ENSMUST00000155882.1
Fhl1


four and a half LIM domains 1


chr10_+_85386813 1.128 ENSMUST00000105307.1
ENSMUST00000020231.3
Btbd11

BTB (POZ) domain containing 11

chr1_-_126738167 1.115 ENSMUST00000160693.1
Nckap5
NCK-associated protein 5
chr18_+_56432116 1.098 ENSMUST00000070166.5
Gramd3
GRAM domain containing 3
chr14_+_73237891 1.084 ENSMUST00000044405.6
Lpar6
lysophosphatidic acid receptor 6
chr14_+_67745229 1.060 ENSMUST00000111095.2
Gnrh1
gonadotropin releasing hormone 1
chr12_-_111813834 1.049 ENSMUST00000021715.5
Xrcc3
X-ray repair complementing defective repair in Chinese hamster cells 3
chr18_-_39487096 1.043 ENSMUST00000097592.2
ENSMUST00000115571.1
Nr3c1

nuclear receptor subfamily 3, group C, member 1

chr2_+_109917639 1.038 ENSMUST00000046548.7
ENSMUST00000111037.2
Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chr3_+_125404292 1.032 ENSMUST00000144344.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chrX_-_74246534 1.007 ENSMUST00000101454.2
ENSMUST00000033699.6
Flna

filamin, alpha

chr15_+_25742314 0.997 ENSMUST00000135981.1
Myo10
myosin X
chr4_+_13751297 0.982 ENSMUST00000105566.2
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr13_+_23544052 0.975 ENSMUST00000075558.2
Hist1h3f
histone cluster 1, H3f
chr6_-_99266494 0.971 ENSMUST00000113326.2
Foxp1
forkhead box P1
chrX_-_53269786 0.966 ENSMUST00000114841.1
ENSMUST00000071023.5
Fam122b

family with sequence similarity 122, member B

chr1_-_190170671 0.960 ENSMUST00000175916.1
Prox1
prospero-related homeobox 1
chr10_+_99263224 0.959 ENSMUST00000020118.4
Dusp6
dual specificity phosphatase 6
chr7_-_45830776 0.948 ENSMUST00000107723.2
ENSMUST00000131384.1
Grwd1

glutamate-rich WD repeat containing 1

chr3_+_121291725 0.947 ENSMUST00000039442.7
Alg14
asparagine-linked glycosylation 14
chr18_-_44662251 0.944 ENSMUST00000164666.1
Mcc
mutated in colorectal cancers
chr2_+_106693185 0.926 ENSMUST00000111063.1
Mpped2
metallophosphoesterase domain containing 2
chr10_-_53647080 0.920 ENSMUST00000169866.1
Fam184a
family with sequence similarity 184, member A
chr1_-_78968079 0.917 ENSMUST00000049117.5
Gm5830
predicted pseudogene 5830
chr6_+_71909046 0.905 ENSMUST00000055296.8
Polr1a
polymerase (RNA) I polypeptide A
chr1_+_156838915 0.895 ENSMUST00000111720.1
Angptl1
angiopoietin-like 1
chr1_+_137928100 0.893 ENSMUST00000054333.2
A130050O07Rik
RIKEN cDNA A130050O07 gene
chr6_-_50456085 0.889 ENSMUST00000146341.1
ENSMUST00000071728.4
Osbpl3

oxysterol binding protein-like 3

chrX_-_134111852 0.889 ENSMUST00000033610.6
Nox1
NADPH oxidase 1
chr10_-_88605017 0.879 ENSMUST00000119185.1
ENSMUST00000121629.1
Mybpc1

myosin binding protein C, slow-type

chr1_-_183147461 0.875 ENSMUST00000171366.1
Disp1
dispatched homolog 1 (Drosophila)
chr17_+_34592248 0.867 ENSMUST00000038149.6
Pbx2
pre B cell leukemia homeobox 2
chr11_+_94327984 0.834 ENSMUST00000107818.2
ENSMUST00000051221.6
Ankrd40

ankyrin repeat domain 40

chr8_-_105568298 0.807 ENSMUST00000005849.5
Agrp
agouti related protein
chr11_-_82890541 0.803 ENSMUST00000092844.6
ENSMUST00000021033.9
ENSMUST00000018985.8
Rad51d


RAD51 homolog D


chr1_+_6734827 0.798 ENSMUST00000139838.1
St18
suppression of tumorigenicity 18
chr2_+_132847719 0.797 ENSMUST00000124836.1
ENSMUST00000154160.1
Crls1

cardiolipin synthase 1

chr14_+_54259227 0.789 ENSMUST00000041197.7
Abhd4
abhydrolase domain containing 4
chr4_+_13743424 0.787 ENSMUST00000006761.3
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr18_-_88927447 0.779 ENSMUST00000147313.1
Socs6
suppressor of cytokine signaling 6
chrX_+_166170449 0.775 ENSMUST00000130880.2
ENSMUST00000056410.4
ENSMUST00000096252.3
ENSMUST00000087169.4
Gemin8



gem (nuclear organelle) associated protein 8



chr13_+_23555023 0.760 ENSMUST00000045301.6
Hist1h1d
histone cluster 1, H1d
chr13_+_75707484 0.753 ENSMUST00000001583.6
Ell2
elongation factor RNA polymerase II 2
chr3_+_125404072 0.753 ENSMUST00000173932.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr13_-_103764502 0.747 ENSMUST00000074616.5
Srek1
splicing regulatory glutamine/lysine-rich protein 1
chr2_+_70474923 0.743 ENSMUST00000100043.2
Sp5
trans-acting transcription factor 5
chr11_+_102604370 0.741 ENSMUST00000057893.5
Fzd2
frizzled homolog 2 (Drosophila)
chr2_-_174464063 0.724 ENSMUST00000016396.7
Atp5e
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit
chr11_-_69666062 0.706 ENSMUST00000108654.2
ENSMUST00000018918.5
Cd68

CD68 antigen

chr11_-_50292302 0.691 ENSMUST00000059458.4
Maml1
mastermind like 1 (Drosophila)
chr12_-_56613270 0.691 ENSMUST00000072631.5
Nkx2-9
NK2 homeobox 9
chr11_+_98798653 0.687 ENSMUST00000037930.6
Msl1
male-specific lethal 1 homolog (Drosophila)
chr13_-_114458720 0.683 ENSMUST00000022287.5
Fst
follistatin
chr4_+_5724304 0.671 ENSMUST00000108380.1
Fam110b
family with sequence similarity 110, member B
chr18_+_6332587 0.666 ENSMUST00000097682.2
Rpl27-ps3
ribosomal protein L27, pseudogene 3
chr6_+_15196949 0.664 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
Foxp2



forkhead box P2



chr8_-_106573461 0.659 ENSMUST00000073722.5
Gm10073
predicted pseudogene 10073
chr12_+_109545390 0.637 ENSMUST00000146701.1
Meg3
maternally expressed 3
chr11_+_94328242 0.607 ENSMUST00000021227.5
Ankrd40
ankyrin repeat domain 40
chr1_+_178798438 0.606 ENSMUST00000160789.1
Kif26b
kinesin family member 26B
chr13_-_100616911 0.605 ENSMUST00000168772.1
ENSMUST00000163163.1
ENSMUST00000022137.7
Marveld2


MARVEL (membrane-associating) domain containing 2


chr1_-_75046639 0.601 ENSMUST00000152855.1
Nhej1
nonhomologous end-joining factor 1
chr1_+_109983737 0.599 ENSMUST00000172005.1
Cdh7
cadherin 7, type 2
chr2_+_163694015 0.579 ENSMUST00000109400.2
Pkig
protein kinase inhibitor, gamma
chr9_+_94669876 0.565 ENSMUST00000033463.9
Slc9a9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr3_-_110143937 0.561 ENSMUST00000051253.3
Ntng1
netrin G1
chr3_-_86548268 0.551 ENSMUST00000077524.3
Mab21l2
mab-21-like 2 (C. elegans)
chr2_-_27475622 0.550 ENSMUST00000138693.1
ENSMUST00000113941.2
ENSMUST00000077737.6
Brd3


bromodomain containing 3


chr5_+_138187485 0.546 ENSMUST00000110934.2
Cnpy4
canopy 4 homolog (zebrafish)
chr2_-_120154600 0.543 ENSMUST00000028755.7
Ehd4
EH-domain containing 4
chr16_-_36071515 0.530 ENSMUST00000004057.7
Fam162a
family with sequence similarity 162, member A
chr10_-_86011833 0.529 ENSMUST00000105304.1
ENSMUST00000061699.5
Bpifc

BPI fold containing family C

chr1_-_89933290 0.509 ENSMUST00000036954.7
Gbx2
gastrulation brain homeobox 2
chr7_-_116084635 0.495 ENSMUST00000111755.3
Gm4353
predicted gene 4353
chr19_-_42202150 0.492 ENSMUST00000018966.7
Sfrp5
secreted frizzled-related sequence protein 5
chr17_+_36958623 0.486 ENSMUST00000173814.1
Znrd1as
Znrd1 antisense
chr11_+_60537978 0.480 ENSMUST00000044250.3
Alkbh5
alkB, alkylation repair homolog 5 (E. coli)
chr8_-_84662841 0.479 ENSMUST00000060427.4
Ier2
immediate early response 2
chr12_+_111814170 0.479 ENSMUST00000021714.7
Zfyve21
zinc finger, FYVE domain containing 21
chr10_+_73821857 0.476 ENSMUST00000177128.1
ENSMUST00000064562.7
ENSMUST00000129404.2
ENSMUST00000105426.3
ENSMUST00000131321.2
ENSMUST00000126920.2
ENSMUST00000147189.2
ENSMUST00000105424.3
ENSMUST00000092420.6
ENSMUST00000105429.3
ENSMUST00000131724.2
ENSMUST00000152655.2
ENSMUST00000151116.2
ENSMUST00000155701.2
ENSMUST00000152819.2
ENSMUST00000125517.2
ENSMUST00000124046.1
ENSMUST00000149977.2
ENSMUST00000146682.1
ENSMUST00000177107.1
Pcdh15



















protocadherin 15



















chr10_+_115569986 0.467 ENSMUST00000173620.1
A930009A15Rik
RIKEN cDNA A930009A15 gene
chr14_-_77036081 0.464 ENSMUST00000142300.1
Lacc1
laccase (multicopper oxidoreductase) domain containing 1
chr9_+_121950988 0.462 ENSMUST00000043011.7
Fam198a
family with sequence similarity 198, member A
chr5_+_123907175 0.461 ENSMUST00000023869.8
Denr
density-regulated protein
chr5_+_42067960 0.457 ENSMUST00000087332.4
Gm16223
predicted gene 16223
chr1_+_12718496 0.453 ENSMUST00000088585.3
Sulf1
sulfatase 1
chr11_+_116671658 0.450 ENSMUST00000106378.1
ENSMUST00000144049.1
1810032O08Rik

RIKEN cDNA 1810032O08 gene

chr2_+_110597298 0.449 ENSMUST00000045972.6
ENSMUST00000111026.2
Slc5a12

solute carrier family 5 (sodium/glucose cotransporter), member 12

chr12_-_73047179 0.433 ENSMUST00000050029.7
Six1
sine oculis-related homeobox 1
chr7_-_37773555 0.420 ENSMUST00000176534.1
Zfp536
zinc finger protein 536
chr11_-_31671863 0.412 ENSMUST00000058060.7
Bod1
biorientation of chromosomes in cell division 1
chr9_+_72806874 0.408 ENSMUST00000055535.8
Prtg
protogenin homolog (Gallus gallus)
chr17_-_24073479 0.405 ENSMUST00000017090.5
Kctd5
potassium channel tetramerisation domain containing 5
chr16_-_76373827 0.403 ENSMUST00000121927.1
Nrip1
nuclear receptor interacting protein 1
chr14_+_79515618 0.394 ENSMUST00000110835.1
Elf1
E74-like factor 1
chr11_+_76243715 0.391 ENSMUST00000040577.4
Rnmtl1
RNA methyltransferase like 1

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
8.4 25.3 GO:0061075 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
3.3 13.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
2.1 8.3 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
1.8 5.5 GO:0061357 Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356) positive regulation of Wnt protein secretion(GO:0061357)
1.5 10.3 GO:0019532 oxalate transport(GO:0019532)
1.4 15.6 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
1.3 5.1 GO:0061743 motor learning(GO:0061743)
1.2 7.2 GO:0006570 tyrosine metabolic process(GO:0006570)
1.2 3.6 GO:0060166 olfactory pit development(GO:0060166)
1.1 7.9 GO:0048752 semicircular canal morphogenesis(GO:0048752)
1.1 4.4 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.9 1.9 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.9 7.5 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.9 7.3 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.9 4.6 GO:0006538 glutamate catabolic process(GO:0006538)
0.8 2.3 GO:0038044 negative regulation of receptor biosynthetic process(GO:0010871) transforming growth factor-beta secretion(GO:0038044)
0.6 1.8 GO:0060023 soft palate development(GO:0060023)
0.6 1.8 GO:0090274 positive regulation of somatostatin secretion(GO:0090274)
0.6 1.7 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.5 1.6 GO:0035880 embryonic nail plate morphogenesis(GO:0035880) positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364)
0.5 2.0 GO:0021648 zygotic determination of anterior/posterior axis, embryo(GO:0007354) cranial nerve formation(GO:0021603) vestibulocochlear nerve morphogenesis(GO:0021648)
0.5 0.5 GO:2000040 regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.5 1.9 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.5 1.0 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.5 2.9 GO:0002317 plasma cell differentiation(GO:0002317)
0.5 2.9 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.5 7.2 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.4 9.2 GO:0007530 sex determination(GO:0007530)
0.4 1.3 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.4 0.4 GO:0072106 regulation of ureteric bud formation(GO:0072106) positive regulation of ureteric bud formation(GO:0072107)
0.4 2.5 GO:0045218 zonula adherens maintenance(GO:0045218)
0.4 1.9 GO:0052695 cellular glucuronidation(GO:0052695)
0.3 1.0 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.3 1.0 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.3 1.9 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.3 1.2 GO:0002326 B cell lineage commitment(GO:0002326)
0.3 0.9 GO:0045113 regulation of integrin biosynthetic process(GO:0045113)
0.3 2.5 GO:0010587 miRNA catabolic process(GO:0010587)
0.3 2.7 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.3 1.3 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation by host of viral process(GO:0044793) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.2 0.7 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.2 6.1 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.2 0.7 GO:0003162 atrioventricular node development(GO:0003162)
0.2 1.1 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.2 1.0 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.2 3.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2 0.6 GO:0072092 ureteric bud invasion(GO:0072092)
0.2 3.4 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.2 3.9 GO:0030903 notochord development(GO:0030903)
0.2 1.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 0.9 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.2 1.2 GO:0015791 polyol transport(GO:0015791) bile acid secretion(GO:0032782)
0.2 0.9 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.2 2.6 GO:0003334 keratinocyte development(GO:0003334)
0.1 1.4 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.1 0.7 GO:0051798 positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798)
0.1 0.4 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 1.7 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.1 0.8 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.1 1.7 GO:0030497 fatty acid elongation(GO:0030497)
0.1 0.5 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.1 0.8 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.5 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.8 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.8 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.1 1.0 GO:0061470 interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619)
0.1 0.7 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 0.3 GO:0002014 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014)
0.1 1.6 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.2 GO:0000966 RNA 5'-end processing(GO:0000966)
0.1 0.9 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 1.3 GO:0001553 luteinization(GO:0001553)
0.1 0.9 GO:0060539 diaphragm development(GO:0060539)
0.1 0.4 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
0.1 5.3 GO:0048706 embryonic skeletal system development(GO:0048706)
0.1 1.7 GO:0003351 epithelial cilium movement(GO:0003351)
0.1 2.7 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 0.5 GO:0021546 rhombomere development(GO:0021546)
0.1 1.2 GO:0045332 phospholipid translocation(GO:0045332)
0.1 2.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.5 GO:0050957 equilibrioception(GO:0050957)
0.1 0.9 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 0.8 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.1 3.0 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.1 8.4 GO:0030326 embryonic limb morphogenesis(GO:0030326) embryonic appendage morphogenesis(GO:0035113)
0.1 2.6 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.1 0.2 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 1.7 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.1 0.2 GO:0035937 androgen catabolic process(GO:0006710) estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.1 3.6 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.1 0.6 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.6 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.6 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.1 0.6 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.3 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.1 GO:0002677 negative regulation of chronic inflammatory response(GO:0002677)
0.0 1.8 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 5.5 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 1.1 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 2.1 GO:0071774 response to fibroblast growth factor(GO:0071774)
0.0 0.4 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.5 GO:0006907 pinocytosis(GO:0006907)
0.0 2.5 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 0.4 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.4 GO:0014741 negative regulation of cardiac muscle hypertrophy(GO:0010614) negative regulation of muscle hypertrophy(GO:0014741)
0.0 0.7 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 2.1 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.3 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.6 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.3 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.3 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.0 3.2 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.0 0.3 GO:0035067 negative regulation of histone acetylation(GO:0035067)
0.0 4.4 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.5 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.3 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.8 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.6 GO:0061028 establishment of endothelial barrier(GO:0061028)
0.0 0.1 GO:0086023 adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.0 0.1 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0 1.4 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.0 5.4 GO:0007059 chromosome segregation(GO:0007059)
0.0 0.6 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.7 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 1.6 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 0.1 GO:0002227 innate immune response in mucosa(GO:0002227)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 7.3 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.8 2.3 GO:0034684 integrin alphav-beta5 complex(GO:0034684)
0.7 4.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.4 1.2 GO:0071953 elastic fiber(GO:0071953)
0.4 1.9 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.3 6.8 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.2 3.9 GO:0005614 interstitial matrix(GO:0005614)
0.2 0.9 GO:0071438 invadopodium membrane(GO:0071438)
0.2 1.0 GO:0031523 Myb complex(GO:0031523)
0.2 1.6 GO:0071439 clathrin complex(GO:0071439)
0.2 1.7 GO:0005915 zonula adherens(GO:0005915)
0.1 5.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 0.9 GO:0005859 muscle myosin complex(GO:0005859)
0.1 0.7 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 1.9 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.7 GO:0072487 MSL complex(GO:0072487)
0.1 0.8 GO:0005796 Golgi lumen(GO:0005796)
0.1 1.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 3.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.6 GO:0061689 paranodal junction(GO:0033010) tricellular tight junction(GO:0061689)
0.1 0.6 GO:0032807 DNA ligase IV complex(GO:0032807)
0.1 4.9 GO:0016459 myosin complex(GO:0016459)
0.1 0.7 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 22.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 2.3 GO:0043034 costamere(GO:0043034)
0.1 2.7 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.1 2.6 GO:0002102 podosome(GO:0002102)
0.1 0.8 GO:0032797 SMN complex(GO:0032797)
0.1 0.9 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 2.7 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.7 GO:0000786 nucleosome(GO:0000786)
0.0 2.6 GO:0005871 kinesin complex(GO:0005871)
0.0 0.3 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 1.8 GO:0043195 terminal bouton(GO:0043195)
0.0 0.7 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.9 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 1.7 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 3.0 GO:0000792 heterochromatin(GO:0000792)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.8 GO:0001772 immunological synapse(GO:0001772)
0.0 1.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.8 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 1.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.0 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.5 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 4.9 GO:0016607 nuclear speck(GO:0016607)
0.0 1.4 GO:0043204 perikaryon(GO:0043204)
0.0 0.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 75.3 GO:0005634 nucleus(GO:0005634)
0.0 2.6 GO:0005578 proteinaceous extracellular matrix(GO:0005578)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 13.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.9 10.3 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.9 7.5 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.9 3.6 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.9 4.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.8 2.5 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.7 6.5 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.7 4.6 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.6 7.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.6 1.7 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.6 7.2 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.5 2.5 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.4 2.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.3 1.4 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.3 1.2 GO:0015254 glycerol channel activity(GO:0015254)
0.3 0.9 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.3 5.1 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.3 1.9 GO:0000150 recombinase activity(GO:0000150)
0.3 1.0 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.3 1.8 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.2 5.5 GO:0001968 fibronectin binding(GO:0001968)
0.2 8.1 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 1.7 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.2 1.9 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.2 2.5 GO:0070097 delta-catenin binding(GO:0070097)
0.2 1.2 GO:0070644 vitamin D response element binding(GO:0070644)
0.2 1.3 GO:0001849 complement component C1q binding(GO:0001849)
0.2 1.3 GO:0050693 LBD domain binding(GO:0050693)
0.2 1.4 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.2 0.9 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.2 3.1 GO:0070410 co-SMAD binding(GO:0070410)
0.2 2.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 1.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 3.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 3.2 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.5 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.1 1.7 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 1.1 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 3.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 1.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.8 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 10.2 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 3.4 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 12.6 GO:0003774 motor activity(GO:0003774)
0.1 1.0 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 0.3 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.1 0.3 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.1 0.9 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 2.0 GO:0070888 E-box binding(GO:0070888)
0.1 1.3 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987)
0.1 0.7 GO:0048185 activin binding(GO:0048185)
0.1 0.4 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 2.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.4 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 0.9 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 33.3 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1 0.6 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 0.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 1.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.9 GO:0015197 peptide transporter activity(GO:0015197)
0.1 0.7 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.9 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 0.4 GO:0031419 cobalamin binding(GO:0031419)
0.1 1.9 GO:0005504 fatty acid binding(GO:0005504)
0.1 35.7 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 0.4 GO:0039706 co-receptor binding(GO:0039706) BMP receptor binding(GO:0070700)
0.0 0.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 1.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.3 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 1.0 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 1.7 GO:0015144 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.0 0.6 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.8 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.7 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.3 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 1.3 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.2 GO:1990405 protein antigen binding(GO:1990405)
0.0 0.4 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.0 0.6 GO:0043566 structure-specific DNA binding(GO:0043566)
0.0 1.1 GO:0005179 hormone activity(GO:0005179)
0.0 0.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.9 GO:0032934 cholesterol binding(GO:0015485) sterol binding(GO:0032934)
0.0 1.8 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.0 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 2.0 GO:0000287 magnesium ion binding(GO:0000287)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 16.8 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.2 18.7 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 2.3 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 5.6 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.1 5.5 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.1 1.1 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 1.1 PID_AR_NONGENOMIC_PATHWAY Nongenotropic Androgen signaling
0.1 3.6 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.1 6.2 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 3.3 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 3.1 PID_BMP_PATHWAY BMP receptor signaling
0.1 1.8 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.1 1.4 PID_S1P_S1P3_PATHWAY S1P3 pathway
0.1 6.1 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.1 1.4 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 0.8 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.1 1.1 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.6 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 7.7 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 2.0 PID_INTEGRIN1_PATHWAY Beta1 integrin cell surface interactions
0.0 1.7 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 2.4 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 4.4 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.2 PID_MYC_PATHWAY C-MYC pathway
0.0 0.6 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.5 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.4 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 1.0 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.3 PID_PLK1_PATHWAY PLK1 signaling events
0.0 1.0 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 0.8 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 2.0 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.7 PID_NOTCH_PATHWAY Notch signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 8.6 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.4 1.1 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
0.2 12.0 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.2 1.9 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.2 4.6 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.2 9.7 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.2 1.2 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 2.3 REACTOME_PECAM1_INTERACTIONS Genes involved in PECAM1 interactions
0.1 2.1 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 1.0 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.1 4.9 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.1 3.1 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 9.1 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 1.9 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.1 1.1 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 1.7 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 3.5 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 1.4 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 0.8 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.1 0.5 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.1 0.9 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 0.9 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 1.7 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 1.8 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.7 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.2 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.2 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.9 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.5 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.9 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.0 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.5 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 1.5 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.3 REACTOME_KINESINS Genes involved in Kinesins
0.0 0.4 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.1 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG