Motif ID: Rora

Z-value: 0.921


Transcription factors associated with Rora:

Gene SymbolEntrez IDGene Name
Rora ENSMUSG00000032238.11 Rora

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Roramm10_v2_chr9_+_68653761_686537860.261.0e-01Click!


Activity profile for motif Rora.

activity profile for motif Rora


Sorted Z-values histogram for motif Rora

Sorted Z-values for motif Rora



Network of associatons between targets according to the STRING database.



First level regulatory network of Rora

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_66801577 5.472 ENSMUST00000168589.1
Sla
src-like adaptor
chr16_+_11406618 4.179 ENSMUST00000122168.1
Snx29
sorting nexin 29
chr9_-_75597643 4.054 ENSMUST00000164100.1
Tmod2
tropomodulin 2
chr1_+_159737510 3.668 ENSMUST00000111669.3
Tnr
tenascin R
chr5_-_106696819 3.660 ENSMUST00000127434.1
ENSMUST00000112696.1
ENSMUST00000112698.1
Zfp644


zinc finger protein 644


chr3_-_107517321 3.571 ENSMUST00000166892.1
Slc6a17
solute carrier family 6 (neurotransmitter transporter), member 17
chr2_+_4300462 3.493 ENSMUST00000175669.1
Frmd4a
FERM domain containing 4A
chr7_-_12422751 3.435 ENSMUST00000080348.5
Zfp551
zinc fingr protein 551
chr11_+_42419729 3.397 ENSMUST00000007797.4
Gabrb2
gamma-aminobutyric acid (GABA) A receptor, subunit beta 2
chr5_+_37028329 3.200 ENSMUST00000173836.1
Jakmip1
janus kinase and microtubule interacting protein 1
chr10_-_8518801 3.137 ENSMUST00000061601.7
Ust
uronyl-2-sulfotransferase
chr5_-_113015473 3.120 ENSMUST00000065167.4
Adrbk2
adrenergic receptor kinase, beta 2
chr16_+_10545390 3.106 ENSMUST00000115827.1
ENSMUST00000038145.6
ENSMUST00000150894.1
Clec16a


C-type lectin domain family 16, member A


chr2_-_130839683 3.021 ENSMUST00000119422.1
4930402H24Rik
RIKEN cDNA 4930402H24 gene
chr2_-_5676046 2.980 ENSMUST00000114987.3
Camk1d
calcium/calmodulin-dependent protein kinase ID
chr19_-_37207293 2.943 ENSMUST00000132580.1
ENSMUST00000079754.4
ENSMUST00000136286.1
ENSMUST00000126188.1
ENSMUST00000126781.1
Cpeb3




cytoplasmic polyadenylation element binding protein 3




chr5_+_19227046 2.935 ENSMUST00000088516.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr5_-_106696530 2.906 ENSMUST00000137285.1
ENSMUST00000124263.1
ENSMUST00000112695.1
ENSMUST00000155495.1
ENSMUST00000135108.1
Zfp644




zinc finger protein 644




chr2_+_29965560 2.875 ENSMUST00000113717.1
ENSMUST00000113719.2
ENSMUST00000100225.2
ENSMUST00000113741.1
ENSMUST00000095083.4
ENSMUST00000046257.7
Sptan1





spectrin alpha, non-erythrocytic 1





chr17_-_43667015 2.846 ENSMUST00000024705.4
Slc25a27
solute carrier family 25, member 27
chr9_-_54501496 2.690 ENSMUST00000118600.1
ENSMUST00000118163.1
Dmxl2

Dmx-like 2

chr15_-_72546279 2.687 ENSMUST00000044624.6
Kcnk9
potassium channel, subfamily K, member 9
chr2_-_121806988 2.576 ENSMUST00000110592.1
Frmd5
FERM domain containing 5
chrX_+_86191764 2.516 ENSMUST00000026036.4
Nr0b1
nuclear receptor subfamily 0, group B, member 1
chr12_-_16589743 2.348 ENSMUST00000111067.2
ENSMUST00000067124.5
Lpin1

lipin 1

chr16_-_44139630 2.331 ENSMUST00000137557.1
ENSMUST00000147025.1
Atp6v1a

ATPase, H+ transporting, lysosomal V1 subunit A

chr1_+_127204986 2.264 ENSMUST00000038361.4
Mgat5
mannoside acetylglucosaminyltransferase 5
chr2_-_121807024 2.206 ENSMUST00000138157.1
Frmd5
FERM domain containing 5
chr19_-_37176055 2.192 ENSMUST00000142973.1
ENSMUST00000154376.1
Cpeb3

cytoplasmic polyadenylation element binding protein 3

chr17_-_46831413 2.178 ENSMUST00000040624.5
Gltscr1l
GLTSCR1-like
chr11_+_97450136 2.132 ENSMUST00000107601.1
Arhgap23
Rho GTPase activating protein 23
chr3_-_158562199 2.113 ENSMUST00000106044.1
Lrrc7
leucine rich repeat containing 7
chr7_+_114768736 2.074 ENSMUST00000117543.1
Insc
inscuteable homolog (Drosophila)
chr2_+_178119166 2.054 ENSMUST00000108916.1
Phactr3
phosphatase and actin regulator 3
chr3_+_36863102 2.042 ENSMUST00000057272.8
4932438A13Rik
RIKEN cDNA 4932438A13 gene
chr17_-_46546275 2.011 ENSMUST00000182485.1
ENSMUST00000066026.7
Cul9

cullin 9

chr11_+_93996082 2.005 ENSMUST00000041956.7
Spag9
sperm associated antigen 9
chr2_-_25501717 1.988 ENSMUST00000015227.3
C8g
complement component 8, gamma polypeptide
chr13_+_9276477 1.980 ENSMUST00000174552.1
Dip2c
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr2_+_178118975 1.964 ENSMUST00000108917.1
Phactr3
phosphatase and actin regulator 3
chr1_-_167393826 1.950 ENSMUST00000028005.2
Mgst3
microsomal glutathione S-transferase 3
chr17_-_17624458 1.931 ENSMUST00000041047.2
Lnpep
leucyl/cystinyl aminopeptidase
chr19_-_46327121 1.861 ENSMUST00000041391.4
ENSMUST00000096029.5
Psd

pleckstrin and Sec7 domain containing

chr12_-_86988676 1.853 ENSMUST00000095521.2
Zdhhc22
zinc finger, DHHC-type containing 22
chr19_-_57314896 1.812 ENSMUST00000111524.1
Ablim1
actin-binding LIM protein 1
chr2_+_48949495 1.807 ENSMUST00000112745.1
Mbd5
methyl-CpG binding domain protein 5
chr12_+_33314277 1.675 ENSMUST00000133549.1
Atxn7l1
ataxin 7-like 1
chr11_-_97573929 1.669 ENSMUST00000126287.1
ENSMUST00000107590.1
Srcin1

SRC kinase signaling inhibitor 1

chr15_+_80091320 1.659 ENSMUST00000009728.6
ENSMUST00000009727.5
Syngr1

synaptogyrin 1

chr16_-_20426375 1.647 ENSMUST00000079158.6
Abcc5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr6_-_113531575 1.615 ENSMUST00000032425.5
Emc3
ER membrane protein complex subunit 3
chr14_-_20794009 1.585 ENSMUST00000100837.3
ENSMUST00000080440.6
ENSMUST00000071816.6
Camk2g


calcium/calmodulin-dependent protein kinase II gamma


chr11_+_70023905 1.571 ENSMUST00000124568.2
Dlg4
discs, large homolog 4 (Drosophila)
chr7_-_25005895 1.563 ENSMUST00000102858.3
ENSMUST00000080882.6
Atp1a3

ATPase, Na+/K+ transporting, alpha 3 polypeptide

chr5_+_63649335 1.535 ENSMUST00000159584.1
3110047P20Rik
RIKEN cDNA 3110047P20 gene
chr17_+_33638056 1.504 ENSMUST00000052079.7
Pram1
PML-RAR alpha-regulated adaptor molecule 1
chr10_+_67185730 1.471 ENSMUST00000173689.1
Jmjd1c
jumonji domain containing 1C
chr11_-_116198701 1.459 ENSMUST00000072948.4
Acox1
acyl-Coenzyme A oxidase 1, palmitoyl
chr14_+_64589802 1.351 ENSMUST00000180610.1
A930011O12Rik
RIKEN cDNA A930011O12 gene
chr11_-_69602741 1.343 ENSMUST00000138694.1
Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr2_+_25262589 1.342 ENSMUST00000114336.3
Tprn
taperin
chr1_+_32172711 1.339 ENSMUST00000027226.5
Khdrbs2
KH domain containing, RNA binding, signal transduction associated 2
chr7_-_134232005 1.329 ENSMUST00000134504.1
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr11_+_74830920 1.325 ENSMUST00000000291.2
Mnt
max binding protein
chr11_+_70764209 1.316 ENSMUST00000060444.5
Zfp3
zinc finger protein 3
chr8_+_112011359 1.316 ENSMUST00000052138.9
Terf2ip
telomeric repeat binding factor 2, interacting protein
chr11_+_98741805 1.310 ENSMUST00000064187.5
Thra
thyroid hormone receptor alpha
chr16_-_20426322 1.309 ENSMUST00000115547.2
ENSMUST00000096199.4
Abcc5

ATP-binding cassette, sub-family C (CFTR/MRP), member 5

chr7_-_141429433 1.307 ENSMUST00000124444.1
Cend1
cell cycle exit and neuronal differentiation 1
chr17_-_35909626 1.293 ENSMUST00000141132.1
Atat1
alpha tubulin acetyltransferase 1
chr8_+_70863127 1.287 ENSMUST00000050921.2
A230052G05Rik
RIKEN cDNA A230052G05 gene
chr7_-_141429351 1.263 ENSMUST00000164387.1
ENSMUST00000137488.1
ENSMUST00000084436.3
Cend1


cell cycle exit and neuronal differentiation 1


chr4_+_43632185 1.243 ENSMUST00000107874.2
Npr2
natriuretic peptide receptor 2
chr2_+_32628390 1.235 ENSMUST00000156578.1
Ak1
adenylate kinase 1
chr8_-_64205970 1.230 ENSMUST00000066166.4
Tll1
tolloid-like
chr7_+_45705088 1.196 ENSMUST00000080885.3
Dbp
D site albumin promoter binding protein
chr6_-_29165003 1.171 ENSMUST00000007993.9
Rbm28
RNA binding motif protein 28
chrX_-_107816238 1.161 ENSMUST00000120722.1
2610002M06Rik
RIKEN cDNA 2610002M06 gene
chr11_+_54304180 1.131 ENSMUST00000108904.3
ENSMUST00000108905.3
Acsl6

acyl-CoA synthetase long-chain family member 6

chr4_-_108780503 1.118 ENSMUST00000106658.1
Zfyve9
zinc finger, FYVE domain containing 9
chr15_-_98221056 1.114 ENSMUST00000170618.1
ENSMUST00000141911.1
Olfr287

olfactory receptor 287

chr5_-_122779278 1.108 ENSMUST00000111668.3
Camkk2
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr16_+_10545339 1.108 ENSMUST00000066345.7
ENSMUST00000115824.3
ENSMUST00000155633.1
Clec16a


C-type lectin domain family 16, member A


chr12_-_81333129 1.100 ENSMUST00000085238.6
ENSMUST00000182208.1
Slc8a3

solute carrier family 8 (sodium/calcium exchanger), member 3

chr11_+_75193783 1.097 ENSMUST00000102514.3
Rtn4rl1
reticulon 4 receptor-like 1
chr3_-_133544390 1.094 ENSMUST00000098603.3
Tet2
tet methylcytosine dioxygenase 2
chr5_+_13399309 1.091 ENSMUST00000030714.7
ENSMUST00000141968.1
Sema3a

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A

chr11_+_69088490 1.089 ENSMUST00000021273.6
ENSMUST00000117780.1
Vamp2

vesicle-associated membrane protein 2

chr17_-_35910032 1.087 ENSMUST00000141662.1
ENSMUST00000056034.6
ENSMUST00000077494.6
ENSMUST00000149277.1
ENSMUST00000061052.5
Atat1




alpha tubulin acetyltransferase 1




chr4_-_108780782 1.086 ENSMUST00000106657.1
Zfyve9
zinc finger, FYVE domain containing 9
chr11_+_54304005 1.067 ENSMUST00000000145.5
ENSMUST00000138515.1
Acsl6

acyl-CoA synthetase long-chain family member 6

chr9_+_32116040 1.062 ENSMUST00000174641.1
Arhgap32
Rho GTPase activating protein 32
chr7_-_31126945 1.038 ENSMUST00000098548.4
Scn1b
sodium channel, voltage-gated, type I, beta
chr6_+_29853746 1.027 ENSMUST00000064872.6
ENSMUST00000152581.1
ENSMUST00000176265.1
ENSMUST00000154079.1
Ahcyl2



S-adenosylhomocysteine hydrolase-like 2



chr12_+_109545390 1.013 ENSMUST00000146701.1
Meg3
maternally expressed 3
chr5_-_66514815 1.000 ENSMUST00000161879.1
ENSMUST00000159357.1
Apbb2

amyloid beta (A4) precursor protein-binding, family B, member 2

chr5_-_123141067 0.993 ENSMUST00000162697.1
ENSMUST00000160321.1
ENSMUST00000159637.1
AI480526


expressed sequence AI480526


chr14_-_52213379 0.988 ENSMUST00000140603.1
Chd8
chromodomain helicase DNA binding protein 8
chr14_-_70630149 0.987 ENSMUST00000022694.9
Dmtn
dematin actin binding protein
chr16_-_44139196 0.985 ENSMUST00000063661.6
ENSMUST00000114666.2
Atp6v1a

ATPase, H+ transporting, lysosomal V1 subunit A

chr2_+_170731807 0.972 ENSMUST00000029075.4
Dok5
docking protein 5
chr11_+_113619318 0.969 ENSMUST00000146390.2
ENSMUST00000106630.1
Sstr2

somatostatin receptor 2

chr7_-_81454751 0.968 ENSMUST00000098331.3
ENSMUST00000178892.1
Cpeb1

cytoplasmic polyadenylation element binding protein 1

chr8_-_84937347 0.963 ENSMUST00000109741.2
ENSMUST00000119820.1
Mast1

microtubule associated serine/threonine kinase 1

chr1_-_12991109 0.953 ENSMUST00000115403.2
ENSMUST00000115402.1
Slco5a1

solute carrier organic anion transporter family, member 5A1

chr9_-_43116514 0.952 ENSMUST00000061833.4
Tmem136
transmembrane protein 136
chr8_-_71486037 0.930 ENSMUST00000093450.4
Ano8
anoctamin 8
chr11_+_54303798 0.928 ENSMUST00000093106.5
Acsl6
acyl-CoA synthetase long-chain family member 6
chr19_+_6400523 0.925 ENSMUST00000146831.1
ENSMUST00000035716.8
ENSMUST00000138555.1
ENSMUST00000167240.1
Rasgrp2



RAS, guanyl releasing protein 2



chr17_+_37046555 0.916 ENSMUST00000172789.1
Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr9_+_54586450 0.906 ENSMUST00000167866.1
Idh3a
isocitrate dehydrogenase 3 (NAD+) alpha
chr4_-_19708922 0.898 ENSMUST00000108246.2
Wwp1
WW domain containing E3 ubiquitin protein ligase 1
chr5_+_144100387 0.897 ENSMUST00000041804.7
Lmtk2
lemur tyrosine kinase 2
chr15_-_42676967 0.892 ENSMUST00000022921.5
Angpt1
angiopoietin 1
chr2_+_130406478 0.882 ENSMUST00000055421.4
Tmem239
transmembrane 239
chr10_+_127195240 0.868 ENSMUST00000181578.1
F420014N23Rik
RIKEN cDNA F420014N23 gene
chr8_-_120228221 0.863 ENSMUST00000183235.1
A330074K22Rik
RIKEN cDNA A330074K22 gene
chr11_-_116199040 0.860 ENSMUST00000066587.5
Acox1
acyl-Coenzyme A oxidase 1, palmitoyl
chr4_+_156215920 0.833 ENSMUST00000105572.1
2310042D19Rik
RIKEN cDNA 2310042D19 gene
chr6_+_72414301 0.811 ENSMUST00000065906.7
Ggcx
gamma-glutamyl carboxylase
chr8_+_95320440 0.765 ENSMUST00000162294.1
Tepp
testis, prostate and placenta expressed
chr8_+_26977336 0.761 ENSMUST00000154256.1
ENSMUST00000127097.1
Zfp703

zinc finger protein 703

chr5_-_3473178 0.754 ENSMUST00000168422.1
Gm17590
predicted gene, 17590
chr17_-_33718591 0.743 ENSMUST00000174040.1
ENSMUST00000173015.1
ENSMUST00000066121.6
ENSMUST00000172767.1
ENSMUST00000173329.1
March2




membrane-associated ring finger (C3HC4) 2




chr19_+_53529100 0.742 ENSMUST00000038287.6
Dusp5
dual specificity phosphatase 5
chr19_-_5688149 0.715 ENSMUST00000068169.5
Pcnxl3
pecanex-like 3 (Drosophila)
chr17_+_79614900 0.713 ENSMUST00000040368.2
Rmdn2
regulator of microtubule dynamics 2
chr5_+_137518880 0.703 ENSMUST00000031727.7
Gigyf1
GRB10 interacting GYF protein 1
chr19_-_6921753 0.694 ENSMUST00000173635.1
Esrra
estrogen related receptor, alpha
chr11_-_20831009 0.691 ENSMUST00000047028.8
Lgalsl
lectin, galactoside binding-like
chr19_-_37178011 0.688 ENSMUST00000133988.1
Cpeb3
cytoplasmic polyadenylation element binding protein 3
chr2_+_129065934 0.667 ENSMUST00000035812.7
Ttl
tubulin tyrosine ligase
chr9_+_119444923 0.655 ENSMUST00000035094.6
ENSMUST00000164213.2
Exog

endo/exonuclease (5'-3'), endonuclease G-like

chr7_+_81858993 0.652 ENSMUST00000041890.1
Tm6sf1
transmembrane 6 superfamily member 1
chr7_+_105554360 0.629 ENSMUST00000046983.8
Smpd1
sphingomyelin phosphodiesterase 1, acid lysosomal
chr1_+_191906743 0.624 ENSMUST00000044954.6
Slc30a1
solute carrier family 30 (zinc transporter), member 1
chr1_+_151344472 0.615 ENSMUST00000023918.6
ENSMUST00000097543.1
ENSMUST00000111887.3
Ivns1abp


influenza virus NS1A binding protein


chrX_+_101449078 0.597 ENSMUST00000033674.5
Itgb1bp2
integrin beta 1 binding protein 2
chr9_-_59486323 0.595 ENSMUST00000165322.1
Arih1
ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila)
chr9_-_53610329 0.591 ENSMUST00000034547.5
Acat1
acetyl-Coenzyme A acetyltransferase 1
chr17_-_24141542 0.590 ENSMUST00000115411.1
ENSMUST00000115409.2
ENSMUST00000115407.2
ENSMUST00000102927.3
Pdpk1



3-phosphoinositide dependent protein kinase 1



chr16_+_17276337 0.587 ENSMUST00000159065.1
ENSMUST00000159494.1
ENSMUST00000159811.1
Tmem191c


transmembrane protein 191C


chr7_-_79386943 0.566 ENSMUST00000053718.8
ENSMUST00000179243.1
Rlbp1

retinaldehyde binding protein 1

chr6_+_87887814 0.565 ENSMUST00000113607.3
ENSMUST00000049966.5
Copg1

coatomer protein complex, subunit gamma 1

chr9_+_108392820 0.562 ENSMUST00000035234.4
1700102P08Rik
RIKEN cDNA 1700102P08 gene
chr4_-_126202583 0.562 ENSMUST00000106142.1
ENSMUST00000169403.1
ENSMUST00000130334.1
Thrap3


thyroid hormone receptor associated protein 3


chr2_+_61593125 0.561 ENSMUST00000112494.1
Tank
TRAF family member-associated Nf-kappa B activator
chr10_-_128370032 0.553 ENSMUST00000043211.5
Coq10a
coenzyme Q10 homolog A (yeast)
chr12_-_110695860 0.546 ENSMUST00000149189.1
Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr11_+_60777525 0.536 ENSMUST00000056907.6
ENSMUST00000102667.3
Smcr8

Smith-Magenis syndrome chromosome region, candidate 8 homolog (human)

chr9_+_96258697 0.524 ENSMUST00000179416.1
Tfdp2
transcription factor Dp 2
chr11_+_121702591 0.523 ENSMUST00000125580.1
Metrnl
meteorin, glial cell differentiation regulator-like
chr7_-_92669917 0.515 ENSMUST00000119954.1
Pcf11
cleavage and polyadenylation factor subunit homolog (S. cerevisiae)
chr7_-_141434532 0.508 ENSMUST00000133021.1
ENSMUST00000106007.3
ENSMUST00000150026.1
ENSMUST00000133206.2
Slc25a22



solute carrier family 25 (mitochondrial carrier, glutamate), member 22



chr5_-_134456702 0.482 ENSMUST00000073161.5
ENSMUST00000171794.2
ENSMUST00000111245.2
ENSMUST00000100654.3
ENSMUST00000167084.2
ENSMUST00000100652.3
ENSMUST00000100650.3
ENSMUST00000074114.5
Gtf2ird1







general transcription factor II I repeat domain-containing 1







chr14_+_21500879 0.476 ENSMUST00000182964.1
Kat6b
K(lysine) acetyltransferase 6B
chr11_-_84870712 0.471 ENSMUST00000170741.1
ENSMUST00000172405.1
ENSMUST00000100686.3
ENSMUST00000108081.2
Ggnbp2



gametogenetin binding protein 2



chr6_+_28215555 0.470 ENSMUST00000143099.1
ENSMUST00000143551.1
6530409C15Rik

RIKEN cDNA 6530409C15 gene

chr18_-_67449083 0.462 ENSMUST00000025408.8
Afg3l2
AFG3(ATPase family gene 3)-like 2 (yeast)
chr15_+_99224976 0.453 ENSMUST00000041415.3
Kcnh3
potassium voltage-gated channel, subfamily H (eag-related), member 3
chr16_+_17276291 0.450 ENSMUST00000164950.1
ENSMUST00000159242.1
Tmem191c

transmembrane protein 191C

chr11_-_59228162 0.438 ENSMUST00000163300.1
ENSMUST00000061242.7
Arf1

ADP-ribosylation factor 1

chr7_+_126272589 0.426 ENSMUST00000056028.9
Sbk1
SH3-binding kinase 1
chr9_+_55326913 0.423 ENSMUST00000085754.3
ENSMUST00000034862.4
AI118078

expressed sequence AI118078

chr6_+_48613180 0.422 ENSMUST00000061720.4
Zfp775
zinc finger protein 775
chr6_-_39419757 0.415 ENSMUST00000146785.1
ENSMUST00000114823.1
Mkrn1

makorin, ring finger protein, 1

chr11_-_48992226 0.404 ENSMUST00000059930.2
ENSMUST00000068063.3
Gm12185
Tgtp1
predicted gene 12185
T cell specific GTPase 1
chr4_-_82859571 0.397 ENSMUST00000156055.1
ENSMUST00000030110.8
Zdhhc21

zinc finger, DHHC domain containing 21

chr11_+_77462325 0.392 ENSMUST00000102493.1
Coro6
coronin 6
chr19_+_46396885 0.365 ENSMUST00000039922.6
ENSMUST00000111867.2
ENSMUST00000120778.1
Sufu


suppressor of fused homolog (Drosophila)


chr14_-_79868398 0.357 ENSMUST00000179430.1
Gm10845
predicted gene 10845
chr10_+_57794335 0.351 ENSMUST00000151623.1
ENSMUST00000020022.7
Smpdl3a

sphingomyelin phosphodiesterase, acid-like 3A

chr2_+_61593077 0.333 ENSMUST00000112495.1
ENSMUST00000112501.2
Tank

TRAF family member-associated Nf-kappa B activator

chr9_+_123150941 0.325 ENSMUST00000026890.4
Clec3b
C-type lectin domain family 3, member b
chr2_+_160731684 0.313 ENSMUST00000174885.1
ENSMUST00000109462.1
Plcg1

phospholipase C, gamma 1

chr11_-_74590065 0.311 ENSMUST00000145524.1
ENSMUST00000047488.7
Rap1gap2

RAP1 GTPase activating protein 2

chr7_-_134232125 0.287 ENSMUST00000127524.1
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr15_+_78430086 0.286 ENSMUST00000162808.1
Kctd17
potassium channel tetramerisation domain containing 17
chr7_-_100547620 0.284 ENSMUST00000064334.2
D630004N19Rik
RIKEN cDNA D630004N19 gene
chr1_+_104768510 0.282 ENSMUST00000062528.8
Cdh20
cadherin 20
chr4_-_140665891 0.280 ENSMUST00000069623.5
Arhgef10l
Rho guanine nucleotide exchange factor (GEF) 10-like
chr6_+_70726430 0.273 ENSMUST00000103410.1
Igkc
immunoglobulin kappa constant
chr11_+_94044331 0.265 ENSMUST00000024979.8
Spag9
sperm associated antigen 9
chr11_-_84870812 0.264 ENSMUST00000168434.1
Ggnbp2
gametogenetin binding protein 2
chr17_-_46153517 0.262 ENSMUST00000171172.1
Mad2l1bp
MAD2L1 binding protein
chr4_-_132075250 0.261 ENSMUST00000105970.1
ENSMUST00000105975.1
Epb4.1

erythrocyte protein band 4.1

chr11_-_84870646 0.255 ENSMUST00000018547.2
Ggnbp2
gametogenetin binding protein 2
chr4_+_131873608 0.248 ENSMUST00000053819.3
Srsf4
serine/arginine-rich splicing factor 4
chr19_+_6399857 0.246 ENSMUST00000146601.1
ENSMUST00000150713.1
Rasgrp2

RAS, guanyl releasing protein 2

chr7_+_83631959 0.239 ENSMUST00000075418.7
ENSMUST00000117410.1
Stard5

StAR-related lipid transfer (START) domain containing 5

chr2_+_132690120 0.216 ENSMUST00000148271.1
ENSMUST00000110132.2
1110034G24Rik

RIKEN cDNA 1110034G24 gene

chr10_-_86011833 0.209 ENSMUST00000105304.1
ENSMUST00000061699.5
Bpifc

BPI fold containing family C

chr11_-_84870188 0.206 ENSMUST00000154915.2
Ggnbp2
gametogenetin binding protein 2
chr19_+_6399746 0.201 ENSMUST00000113468.1
Rasgrp2
RAS, guanyl releasing protein 2
chr1_-_191907527 0.192 ENSMUST00000069573.5
1700034H15Rik
RIKEN cDNA 1700034H15 gene
chr2_+_72054598 0.192 ENSMUST00000028525.5
Rapgef4
Rap guanine nucleotide exchange factor (GEF) 4
chr5_+_115506668 0.172 ENSMUST00000067268.8
ENSMUST00000086523.3
Pxn

paxillin

chr1_-_63176653 0.160 ENSMUST00000027111.8
ENSMUST00000168099.2
Ndufs1

NADH dehydrogenase (ubiquinone) Fe-S protein 1

chr1_+_74542881 0.149 ENSMUST00000113749.1
ENSMUST00000067916.6
ENSMUST00000113745.1
ENSMUST00000113747.1
ENSMUST00000113750.1
Plcd4




phospholipase C, delta 4




chr2_+_152105722 0.124 ENSMUST00000099225.2
Srxn1
sulfiredoxin 1 homolog (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.8 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.9 3.7 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.9 2.6 GO:0021933 radial glia guided migration of cerebellar granule cell(GO:0021933)
0.8 4.2 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.8 2.4 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.7 3.6 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.7 2.8 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.7 4.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.6 1.8 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.6 2.3 GO:0006642 triglyceride mobilization(GO:0006642)
0.6 2.3 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.5 3.1 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.4 1.3 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.4 1.3 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.4 3.0 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.4 3.4 GO:0071420 cellular response to histamine(GO:0071420)
0.4 1.1 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.4 2.9 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.4 1.1 GO:0019858 cytosine metabolic process(GO:0019858)
0.4 1.1 GO:0002447 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
0.4 2.5 GO:0035902 response to immobilization stress(GO:0035902)
0.3 1.0 GO:0086047 membrane depolarization during Purkinje myocyte cell action potential(GO:0086047)
0.3 1.3 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.3 2.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.3 1.0 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.3 2.7 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.3 0.9 GO:0048014 Tie signaling pathway(GO:0048014)
0.3 2.3 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.3 0.8 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.3 2.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.3 1.6 GO:0036376 sodium ion export from cell(GO:0036376)
0.2 1.2 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.2 0.9 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.2 1.1 GO:1990034 calcium ion export from cell(GO:1990034)
0.2 1.1 GO:0021856 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.2 1.5 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.2 0.6 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.2 1.6 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.2 0.6 GO:0006550 isoleucine catabolic process(GO:0006550) acetyl-CoA catabolic process(GO:0046356) ketone body catabolic process(GO:0046952)
0.2 1.5 GO:0043313 regulation of neutrophil degranulation(GO:0043313)
0.2 1.2 GO:0046103 inosine biosynthetic process(GO:0046103)
0.2 3.3 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.1 0.4 GO:0097212 cleavage furrow ingression(GO:0036090) lysosomal membrane organization(GO:0097212)
0.1 1.0 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 1.2 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.5 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 1.6 GO:2000821 regulation of grooming behavior(GO:2000821)
0.1 0.9 GO:0032811 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) negative regulation of epinephrine secretion(GO:0032811)
0.1 0.9 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 1.0 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 1.0 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 2.2 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.1 1.0 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.1 1.9 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.5 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 1.0 GO:0030432 peristalsis(GO:0030432)
0.1 1.7 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 5.5 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 0.3 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.1 3.5 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 1.6 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.1 2.2 GO:0018345 protein palmitoylation(GO:0018345)
0.1 0.8 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.1 2.9 GO:0051693 actin filament capping(GO:0051693)
0.1 0.5 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.5 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 1.0 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 1.1 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.1 1.0 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.1 0.5 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.5 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.1 1.9 GO:0043171 peptide catabolic process(GO:0043171)
0.1 0.6 GO:0051683 establishment of Golgi localization(GO:0051683)
0.1 2.1 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.1 0.7 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.4 GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0 2.0 GO:0051647 nucleus localization(GO:0051647)
0.0 0.2 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.0 0.9 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.0 1.0 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.6 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.0 1.3 GO:0061098 positive regulation of protein tyrosine kinase activity(GO:0061098)
0.0 3.1 GO:0030010 establishment of cell polarity(GO:0030010)
0.0 1.1 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.6 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.3 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.0 0.2 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0 1.9 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.7 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 1.9 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 0.3 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 1.3 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.4 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.8 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.3 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 2.0 GO:0007088 regulation of mitotic nuclear division(GO:0007088)
0.0 2.3 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.7 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.9 GO:0006821 chloride transport(GO:0006821)
0.0 1.0 GO:0030048 actin filament-based movement(GO:0030048)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:0072534 perineuronal net(GO:0072534)
0.6 2.9 GO:0032437 cuticular plate(GO:0032437)
0.4 2.9 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.4 3.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.3 2.9 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.3 6.8 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.3 1.1 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.3 2.4 GO:0097427 microtubule bundle(GO:0097427)
0.2 1.0 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.2 3.4 GO:1902711 GABA-A receptor complex(GO:1902711)
0.2 1.3 GO:0030870 Mre11 complex(GO:0030870)
0.2 0.9 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.2 2.5 GO:0042788 polysomal ribosome(GO:0042788)
0.2 1.2 GO:0001520 outer dense fiber(GO:0001520)
0.2 2.0 GO:0046930 pore complex(GO:0046930)
0.1 0.5 GO:0005745 m-AAA complex(GO:0005745)
0.1 1.6 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 1.8 GO:0010369 chromocenter(GO:0010369)
0.1 1.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 0.6 GO:0097413 Lewy body(GO:0097413)
0.1 1.0 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 2.1 GO:0043194 axon initial segment(GO:0043194)
0.1 1.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.3 GO:0001652 granular component(GO:0001652)
0.1 0.6 GO:0042599 lamellar body(GO:0042599)
0.1 0.5 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.6 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 5.4 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.2 GO:0044316 cone cell pedicle(GO:0044316)
0.0 7.4 GO:0008021 synaptic vesicle(GO:0008021)
0.0 2.8 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.1 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 6.8 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 1.3 GO:0032420 stereocilium(GO:0032420)
0.0 1.3 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 4.5 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 1.0 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 1.6 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 1.7 GO:0030175 filopodium(GO:0030175)
0.0 0.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 5.0 GO:0030426 growth cone(GO:0030426)
0.0 0.5 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 2.8 GO:0045177 apical part of cell(GO:0045177)
0.0 1.3 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.6 GO:0030315 T-tubule(GO:0030315)
0.0 2.3 GO:0031461 cullin-RING ubiquitin ligase complex(GO:0031461)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.4 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.8 2.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.5 2.9 GO:0070699 type II activin receptor binding(GO:0070699)
0.5 6.8 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.5 2.3 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.5 4.1 GO:0005523 tropomyosin binding(GO:0005523)
0.4 1.3 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.4 2.6 GO:0019841 retinol binding(GO:0019841)
0.4 2.4 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.4 2.3 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.3 1.0 GO:0004994 somatostatin receptor activity(GO:0004994)
0.3 0.9 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.3 2.9 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.2 1.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.2 2.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.2 0.9 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.2 3.6 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.2 3.7 GO:0046625 sphingolipid binding(GO:0046625)
0.2 1.6 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.2 1.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.2 1.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.2 6.8 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2 0.9 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.2 2.3 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 1.0 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.6 GO:0016453 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.1 1.0 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 2.5 GO:0050811 GABA receptor binding(GO:0050811)
0.1 4.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 2.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 1.0 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 1.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 1.1 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 2.6 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 1.0 GO:0016004 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.1 1.3 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.1 1.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 1.0 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 0.9 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 1.1 GO:0038191 neuropilin binding(GO:0038191)
0.1 1.9 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 2.5 GO:0000217 DNA secondary structure binding(GO:0000217)
0.1 0.2 GO:0032052 bile acid binding(GO:0032052)
0.1 3.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 2.2 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 1.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.5 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 3.9 GO:0030507 spectrin binding(GO:0030507)
0.1 0.9 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 4.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 1.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 3.1 GO:0008146 sulfotransferase activity(GO:0008146)
0.1 5.6 GO:0030674 protein binding, bridging(GO:0030674)
0.1 0.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 1.0 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.3 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 1.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.5 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 3.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.7 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.6 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 1.0 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.6 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 3.0 GO:0008514 organic anion transmembrane transporter activity(GO:0008514)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 2.6 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 3.8 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.4 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.8 GO:0019842 vitamin binding(GO:0019842)
0.0 0.1 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.3 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.1 3.0 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.1 1.6 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 0.6 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.1 1.8 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.1 1.3 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.1 1.6 ST_GA12_PATHWAY G alpha 12 Pathway
0.1 3.1 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.0 0.3 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 2.9 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 1.0 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 2.3 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 2.4 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 1.0 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.9 PID_SHP2_PATHWAY SHP2 signaling
0.0 0.8 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.4 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.8 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.6 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.0 1.1 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 2.0 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.0 1.8 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.0 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.4 2.7 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 3.4 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.2 5.8 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.2 3.0 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.2 2.3 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.2 2.3 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.2 2.0 REACTOME_COMPLEMENT_CASCADE Genes involved in Complement cascade
0.2 3.3 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.1 2.3 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.1 3.1 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 1.1 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 0.8 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 2.9 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.1 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 1.1 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.8 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.9 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.1 0.9 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 2.2 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 0.3 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 3.1 REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.1 4.0 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 0.9 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.9 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 1.3 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.0 1.2 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.6 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 1.3 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.4 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.0 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.6 REACTOME_DOWNSTREAM_TCR_SIGNALING Genes involved in Downstream TCR signaling
0.0 0.4 REACTOME_ENOS_ACTIVATION_AND_REGULATION Genes involved in eNOS activation and regulation
0.0 0.6 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.2 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.0 1.5 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.6 REACTOME_SIGNALING_BY_EGFR_IN_CANCER Genes involved in Signaling by EGFR in Cancer
0.0 0.5 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels