Motif ID: Meox1

Z-value: 0.663


Transcription factors associated with Meox1:

Gene SymbolEntrez IDGene Name
Meox1 ENSMUSG00000001493.9 Meox1



Activity profile for motif Meox1.

activity profile for motif Meox1


Sorted Z-values histogram for motif Meox1

Sorted Z-values for motif Meox1



Network of associatons between targets according to the STRING database.



First level regulatory network of Meox1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_8710734 6.636 ENSMUST00000005493.7
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr15_-_8710409 5.119 ENSMUST00000157065.1
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr5_-_134747241 4.264 ENSMUST00000015138.9
Eln
elastin
chr14_-_103843685 3.472 ENSMUST00000172237.1
Ednrb
endothelin receptor type B
chr6_-_36811361 3.398 ENSMUST00000101534.1
Ptn
pleiotrophin
chr11_-_98053415 3.381 ENSMUST00000017544.2
Stac2
SH3 and cysteine rich domain 2
chr2_+_116067213 2.456 ENSMUST00000152412.1
G630016G05Rik
RIKEN cDNA G630016G05 gene
chr4_-_14621805 2.439 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr5_-_62766153 2.291 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr15_-_37459327 2.202 ENSMUST00000119730.1
ENSMUST00000120746.1
Ncald

neurocalcin delta

chr15_-_37458523 2.150 ENSMUST00000116445.2
Ncald
neurocalcin delta
chr5_+_107403496 2.126 ENSMUST00000049146.5
Ephx4
epoxide hydrolase 4
chr9_+_123366921 1.828 ENSMUST00000038863.7
Lars2
leucyl-tRNA synthetase, mitochondrial
chr3_-_113577743 1.560 ENSMUST00000067980.5
Amy1
amylase 1, salivary
chr2_-_116067391 1.513 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr17_-_47833169 1.508 ENSMUST00000131971.1
ENSMUST00000129360.1
ENSMUST00000113280.1
ENSMUST00000132125.1
Mdfi



MyoD family inhibitor



chr15_+_18818895 1.477 ENSMUST00000166873.2
Cdh10
cadherin 10
chr17_-_47833256 1.424 ENSMUST00000152455.1
ENSMUST00000035375.7
Mdfi

MyoD family inhibitor

chr2_-_84425258 1.402 ENSMUST00000074262.2
Calcrl
calcitonin receptor-like
chr8_+_66386292 1.308 ENSMUST00000039540.5
ENSMUST00000110253.2
March1

membrane-associated ring finger (C3HC4) 1

chr15_+_25773985 1.294 ENSMUST00000125667.1
Myo10
myosin X
chr3_-_121263314 1.266 ENSMUST00000029777.7
Tmem56
transmembrane protein 56
chr8_+_23411490 1.217 ENSMUST00000033952.7
Sfrp1
secreted frizzled-related protein 1
chr1_-_163725123 1.204 ENSMUST00000159679.1
Mettl11b
methyltransferase like 11B
chr7_+_103550368 1.161 ENSMUST00000106888.1
Olfr613
olfactory receptor 613
chr15_+_92597104 1.095 ENSMUST00000035399.8
Pdzrn4
PDZ domain containing RING finger 4
chr7_-_140154712 1.061 ENSMUST00000059241.7
Sprn
shadow of prion protein
chr15_+_98571004 0.984 ENSMUST00000023728.6
4930415O20Rik
RIKEN cDNA 4930415O20 gene
chrX_+_73757069 0.951 ENSMUST00000002079.6
Plxnb3
plexin B3
chr18_-_3281036 0.918 ENSMUST00000049942.6
ENSMUST00000139537.1
ENSMUST00000124747.1
Crem


cAMP responsive element modulator


chr14_+_27238018 0.899 ENSMUST00000049206.5
Arhgef3
Rho guanine nucleotide exchange factor (GEF) 3
chrX_+_150547375 0.868 ENSMUST00000066337.6
ENSMUST00000112715.1
Alas2

aminolevulinic acid synthase 2, erythroid

chr2_-_113829069 0.844 ENSMUST00000024005.7
Scg5
secretogranin V
chr7_+_101378183 0.829 ENSMUST00000084895.5
Arap1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chrX_+_136822671 0.765 ENSMUST00000033800.6
Plp1
proteolipid protein (myelin) 1
chr3_+_13946368 0.765 ENSMUST00000171075.1
ENSMUST00000108372.2
Ralyl

RALY RNA binding protein-like

chr5_+_19907502 0.758 ENSMUST00000101558.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr10_-_86011833 0.752 ENSMUST00000105304.1
ENSMUST00000061699.5
Bpifc

BPI fold containing family C

chr5_+_136987019 0.711 ENSMUST00000004968.4
Plod3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr17_+_88440711 0.693 ENSMUST00000112238.2
ENSMUST00000155640.1
Foxn2

forkhead box N2

chrX_+_136822781 0.682 ENSMUST00000113085.1
Plp1
proteolipid protein (myelin) 1
chr7_+_79273201 0.669 ENSMUST00000037315.6
Abhd2
abhydrolase domain containing 2
chr10_+_90071095 0.668 ENSMUST00000183109.1
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr4_-_14621669 0.657 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr7_+_19368498 0.644 ENSMUST00000132655.1
Ppp1r13l
protein phosphatase 1, regulatory (inhibitor) subunit 13 like
chr7_+_126776939 0.640 ENSMUST00000038614.5
ENSMUST00000170882.1
ENSMUST00000106359.1
ENSMUST00000106357.1
ENSMUST00000145762.1
ENSMUST00000132643.1
ENSMUST00000106356.1
Ypel3






yippee-like 3 (Drosophila)






chr4_-_14621494 0.612 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chr5_+_19907774 0.599 ENSMUST00000115267.2
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr9_-_90255927 0.575 ENSMUST00000144646.1
Tbc1d2b
TBC1 domain family, member 2B
chr9_-_95750335 0.563 ENSMUST00000053785.3
Trpc1
transient receptor potential cation channel, subfamily C, member 1
chr8_+_105701142 0.550 ENSMUST00000098444.2
Pard6a
par-6 (partitioning defective 6,) homolog alpha (C. elegans)
chr18_+_12741324 0.500 ENSMUST00000115857.2
ENSMUST00000121018.1
ENSMUST00000119108.1
Cabyr


calcium-binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2)


chr12_-_79296266 0.494 ENSMUST00000021547.6
Zfyve26
zinc finger, FYVE domain containing 26
chr4_-_41464816 0.487 ENSMUST00000108055.2
ENSMUST00000154535.1
ENSMUST00000030148.5
Kif24


kinesin family member 24


chr2_-_29787622 0.483 ENSMUST00000177467.1
ENSMUST00000113807.3
Trub2

TruB pseudouridine (psi) synthase homolog 2 (E. coli)

chr6_+_8520008 0.476 ENSMUST00000162567.1
ENSMUST00000161217.1
Glcci1

glucocorticoid induced transcript 1

chr7_+_30231884 0.458 ENSMUST00000019882.9
Polr2i
polymerase (RNA) II (DNA directed) polypeptide I
chr5_-_62765618 0.451 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr19_-_56548122 0.448 ENSMUST00000026063.5
ENSMUST00000182276.1
Dclre1a

DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae)

chr2_-_91649785 0.439 ENSMUST00000111333.1
Zfp408
zinc finger protein 408
chr2_-_91649751 0.436 ENSMUST00000099714.3
Zfp408
zinc finger protein 408
chrX_+_107255878 0.412 ENSMUST00000101294.2
ENSMUST00000118820.1
ENSMUST00000120971.1
Gpr174


G protein-coupled receptor 174


chr18_+_37300799 0.412 ENSMUST00000051754.1
Pcdhb3
protocadherin beta 3
chr5_-_84417359 0.412 ENSMUST00000113401.1
Epha5
Eph receptor A5
chr1_-_134955908 0.412 ENSMUST00000045665.6
ENSMUST00000086444.4
ENSMUST00000112163.1
Ppp1r12b


protein phosphatase 1, regulatory (inhibitor) subunit 12B


chr2_-_45117349 0.411 ENSMUST00000176438.2
Zeb2
zinc finger E-box binding homeobox 2
chr2_-_45112890 0.395 ENSMUST00000076836.6
Zeb2
zinc finger E-box binding homeobox 2
chr18_+_56432116 0.391 ENSMUST00000070166.5
Gramd3
GRAM domain containing 3
chr1_+_66468364 0.386 ENSMUST00000061620.9
Unc80
unc-80 homolog (C. elegans)
chr11_+_116843278 0.385 ENSMUST00000106370.3
Mettl23
methyltransferase like 23
chr8_+_123477859 0.373 ENSMUST00000001520.7
Afg3l1
AFG3(ATPase family gene 3)-like 1 (yeast)
chr1_-_134955847 0.365 ENSMUST00000168381.1
Ppp1r12b
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr6_+_72097561 0.359 ENSMUST00000069994.4
ENSMUST00000114112.1
St3gal5

ST3 beta-galactoside alpha-2,3-sialyltransferase 5

chrX_+_153139941 0.359 ENSMUST00000039720.4
ENSMUST00000144175.2
Rragb

Ras-related GTP binding B

chr7_+_30232032 0.352 ENSMUST00000149654.1
Polr2i
polymerase (RNA) II (DNA directed) polypeptide I
chr19_-_56822161 0.348 ENSMUST00000118592.1
A630007B06Rik
RIKEN cDNA A630007B06 gene
chr18_-_36744518 0.330 ENSMUST00000014438.4
Ndufa2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2
chr11_+_84129649 0.322 ENSMUST00000133811.1
Acaca
acetyl-Coenzyme A carboxylase alpha
chr3_-_59220150 0.312 ENSMUST00000170388.1
P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr19_-_56548013 0.308 ENSMUST00000182059.1
Dclre1a
DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae)
chr14_-_121915774 0.296 ENSMUST00000055475.7
Gpr18
G protein-coupled receptor 18
chr7_-_4778141 0.295 ENSMUST00000094892.5
Il11
interleukin 11
chr11_-_82890541 0.288 ENSMUST00000092844.6
ENSMUST00000021033.9
ENSMUST00000018985.8
Rad51d


RAD51 homolog D


chr8_-_70139197 0.283 ENSMUST00000075724.7
Rfxank
regulatory factor X-associated ankyrin-containing protein
chr18_-_67245818 0.278 ENSMUST00000073054.3
Mppe1
metallophosphoesterase 1
chr9_-_55919605 0.263 ENSMUST00000037408.8
Scaper
S phase cyclin A-associated protein in the ER
chr1_-_20820213 0.257 ENSMUST00000053266.9
Mcm3
minichromosome maintenance deficient 3 (S. cerevisiae)
chr4_-_117682233 0.239 ENSMUST00000102687.3
Dmap1
DNA methyltransferase 1-associated protein 1
chr2_+_76650264 0.224 ENSMUST00000099986.2
Dfnb59
deafness, autosomal recessive 59 (human)
chr18_+_37355271 0.222 ENSMUST00000051163.1
Pcdhb8
protocadherin beta 8
chr6_-_34317442 0.220 ENSMUST00000154655.1
ENSMUST00000102980.4
Akr1b3

aldo-keto reductase family 1, member B3 (aldose reductase)

chr5_-_96164147 0.214 ENSMUST00000137207.1
Cnot6l
CCR4-NOT transcription complex, subunit 6-like
chr8_-_105701077 0.204 ENSMUST00000042608.6
Acd
adrenocortical dysplasia
chr10_+_81718919 0.197 ENSMUST00000085664.5
Zfp433
RIKEN cDNA 1700123A16 gene
chr10_-_62527438 0.196 ENSMUST00000160987.1
Srgn
serglycin
chr2_+_91650169 0.176 ENSMUST00000090614.4
Arhgap1
Rho GTPase activating protein 1
chr19_+_53140430 0.165 ENSMUST00000111741.2
Add3
adducin 3 (gamma)
chr1_-_93342734 0.163 ENSMUST00000027493.3
Pask
PAS domain containing serine/threonine kinase
chr14_+_118854695 0.159 ENSMUST00000100314.3
Cldn10
claudin 10
chr17_-_45659312 0.140 ENSMUST00000120717.1
Capn11
calpain 11
chr4_-_148159838 0.138 ENSMUST00000151127.1
ENSMUST00000105705.2
Fbxo44

F-box protein 44

chr8_-_54724474 0.133 ENSMUST00000175915.1
Wdr17
WD repeat domain 17
chr5_-_138272786 0.130 ENSMUST00000161279.1
ENSMUST00000161647.1
Gal3st4

galactose-3-O-sulfotransferase 4

chr8_+_85432686 0.125 ENSMUST00000180883.1
1700051O22Rik
RIKEN cDNA 1700051O22 Gene
chr7_+_30232310 0.123 ENSMUST00000108193.1
ENSMUST00000108192.1
Polr2i

polymerase (RNA) II (DNA directed) polypeptide I

chr2_+_91650116 0.123 ENSMUST00000111331.2
Arhgap1
Rho GTPase activating protein 1
chr5_+_144100387 0.108 ENSMUST00000041804.7
Lmtk2
lemur tyrosine kinase 2
chr5_-_122989260 0.107 ENSMUST00000118027.1
Kdm2b
lysine (K)-specific demethylase 2B
chr3_-_130730375 0.107 ENSMUST00000079085.6
Rpl34
ribosomal protein L34
chr4_+_59035088 0.105 ENSMUST00000041160.6
Gng10
guanine nucleotide binding protein (G protein), gamma 10
chr17_-_15566421 0.082 ENSMUST00000178455.1
Gm6686
predicted pseudogene 6686
chrX_-_101086020 0.081 ENSMUST00000113710.1
Slc7a3
solute carrier family 7 (cationic amino acid transporter, y+ system), member 3
chr7_+_28179469 0.070 ENSMUST00000085901.6
ENSMUST00000172761.1
Dyrk1b

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b

chr8_+_64947177 0.054 ENSMUST00000079896.7
ENSMUST00000026595.5
Tmem192

transmembrane protein 192

chr19_-_3575708 0.047 ENSMUST00000113997.2
ENSMUST00000025846.8
ENSMUST00000172362.1
Ppp6r3


protein phosphatase 6, regulatory subunit 3


chr6_-_124779686 0.040 ENSMUST00000147669.1
ENSMUST00000128697.1
ENSMUST00000032218.3
ENSMUST00000112475.2
Lrrc23



leucine rich repeat containing 23



chr13_-_67332525 0.039 ENSMUST00000168892.1
ENSMUST00000109735.2
Zfp595

zinc finger protein 595

chr8_+_83566671 0.029 ENSMUST00000036996.5
Ndufb7
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7
chr8_-_106573461 0.019 ENSMUST00000073722.5
Gm10073
predicted pseudogene 10073
chr9_+_94669876 0.017 ENSMUST00000033463.9
Slc9a9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr10_-_117148474 0.015 ENSMUST00000020381.3
Frs2
fibroblast growth factor receptor substrate 2
chr8_-_86580664 0.015 ENSMUST00000131423.1
ENSMUST00000152438.1
Abcc12

ATP-binding cassette, sub-family C (CFTR/MRP), member 12

chr11_-_59809774 0.011 ENSMUST00000047706.2
ENSMUST00000102697.3
Flcn

folliculin

chr7_+_126950837 0.011 ENSMUST00000106332.1
Sez6l2
seizure related 6 homolog like 2
chr10_-_76110956 0.009 ENSMUST00000120757.1
Slc5a4b
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr2_+_125136692 0.003 ENSMUST00000099452.2
Ctxn2
cortexin 2
chr2_+_69897255 0.000 ENSMUST00000131553.1
Ubr3
ubiquitin protein ligase E3 component n-recognin 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 11.8 GO:0043490 malate-aspartate shuttle(GO:0043490)
1.2 3.5 GO:0014826 vein smooth muscle contraction(GO:0014826)
1.1 3.4 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.5 3.7 GO:0019532 oxalate transport(GO:0019532)
0.4 1.2 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.4 1.4 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.3 0.9 GO:0001193 maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193)
0.2 1.0 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.2 0.7 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.2 1.4 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.2 2.9 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.1 0.8 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.1 0.6 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.1 1.0 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 0.3 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.1 1.3 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 0.3 GO:0044268 multicellular organismal protein metabolic process(GO:0044268)
0.1 0.2 GO:0006059 hexitol metabolic process(GO:0006059) alditol biosynthetic process(GO:0019401)
0.1 1.3 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 0.6 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.1 1.2 GO:0048240 sperm capacitation(GO:0048240)
0.1 0.2 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 0.3 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 0.6 GO:0046541 saliva secretion(GO:0046541)
0.1 0.7 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 0.8 GO:0016486 peptide hormone processing(GO:0016486)
0.1 4.4 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.9 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.3 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.4 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.4 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 1.8 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 4.4 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 1.2 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.0 0.9 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.3 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.4 GO:0034982 mitochondrial protein processing(GO:0034982)
0.0 0.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 1.3 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.5 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.2 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.9 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.1 GO:0015819 lysine transport(GO:0015819) ornithine transport(GO:0015822)
0.0 0.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 1.6 GO:0016052 carbohydrate catabolic process(GO:0016052)
0.0 0.1 GO:0033572 transferrin transport(GO:0033572)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.3 GO:0071953 elastic fiber(GO:0071953)
0.2 1.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.7 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 0.4 GO:0005745 m-AAA complex(GO:0005745)
0.1 0.2 GO:0097454 Schwann cell microvillus(GO:0097454)
0.1 0.4 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.3 GO:0097443 sorting endosome(GO:0097443)
0.1 0.3 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 16.3 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.9 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 1.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 3.4 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.5 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.2 GO:0070187 telosome(GO:0070187)
0.0 0.2 GO:0042629 mast cell granule(GO:0042629)
0.0 1.3 GO:0016459 myosin complex(GO:0016459)
0.0 0.8 GO:0031672 A band(GO:0031672)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.9 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.7 GO:0005802 trans-Golgi network(GO:0005802)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 11.8 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
1.2 3.5 GO:0004962 endothelin receptor activity(GO:0004962)
1.1 3.4 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.5 1.6 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.3 3.7 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.3 0.9 GO:0016748 succinyltransferase activity(GO:0016748)
0.2 1.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 1.2 GO:0004984 olfactory receptor activity(GO:0004984)
0.2 1.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 0.7 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.2 1.4 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.1 1.8 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.1 4.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.3 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 1.0 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1 3.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.8 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 3.6 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 1.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.2 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.3 GO:0000150 recombinase activity(GO:0000150)
0.0 0.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.4 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.0 1.3 GO:0030507 spectrin binding(GO:0030507)
0.0 0.9 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.1 GO:0050694 galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.8 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.6 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 1.2 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 0.4 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.4 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.1 2.7 PID_ARF6_PATHWAY Arf6 signaling events
0.1 3.5 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 4.3 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.3 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 1.2 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 1.7 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.8 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.6 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.3 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.4 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 11.6 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 1.8 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 3.7 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 0.9 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 3.5 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.9 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.1 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 1.0 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 4.8 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.3 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.6 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.5 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.3 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA