Motif ID: Ezh2_Atf2_Ikzf1

Z-value: 1.751

Transcription factors associated with Ezh2_Atf2_Ikzf1:

Gene SymbolEntrez IDGene Name
Atf2 ENSMUSG00000027104.12 Atf2
Ezh2 ENSMUSG00000029687.10 Ezh2
Ikzf1 ENSMUSG00000018654.11 Ikzf1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Atf2mm10_v2_chr2_-_73892530_738925550.923.6e-17Click!
Ezh2mm10_v2_chr6_-_47594967_47595047-0.278.4e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Ezh2_Atf2_Ikzf1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_4300462 16.482 ENSMUST00000175669.1
Frmd4a
FERM domain containing 4A
chr6_+_141524379 13.992 ENSMUST00000032362.9
Slco1c1
solute carrier organic anion transporter family, member 1c1
chr9_+_27790947 13.076 ENSMUST00000115243.2
Opcml
opioid binding protein/cell adhesion molecule-like
chr1_-_154725920 12.497 ENSMUST00000004214.8
Cacna1e
calcium channel, voltage-dependent, R type, alpha 1E subunit
chr14_-_79771305 11.616 ENSMUST00000039568.5
Pcdh8
protocadherin 8
chr2_+_67748212 10.322 ENSMUST00000180887.1
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr9_-_117252450 9.558 ENSMUST00000111773.3
ENSMUST00000068962.7
ENSMUST00000044901.7
Rbms3


RNA binding motif, single stranded interacting protein


chr2_-_66410064 9.313 ENSMUST00000112366.1
Scn1a
sodium channel, voltage-gated, type I, alpha
chr10_-_102490418 8.912 ENSMUST00000020040.3
Nts
neurotensin
chr4_-_82505707 8.462 ENSMUST00000107248.1
ENSMUST00000107247.1
Nfib

nuclear factor I/B

chr17_-_90455872 8.422 ENSMUST00000174337.1
ENSMUST00000172466.1
Nrxn1

neurexin I

chr19_-_28911879 8.374 ENSMUST00000179171.1
AC163993.1
AC163993.1
chr14_-_88471396 8.287 ENSMUST00000061628.5
Pcdh20
protocadherin 20
chr1_+_66175272 7.895 ENSMUST00000156636.2
Map2
microtubule-associated protein 2
chr1_-_169747634 7.826 ENSMUST00000027991.5
ENSMUST00000111357.1
Rgs4

regulator of G-protein signaling 4

chr13_+_42709482 7.742 ENSMUST00000066928.5
ENSMUST00000148891.1
Phactr1

phosphatase and actin regulator 1

chr19_+_26623419 7.497 ENSMUST00000176584.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr6_+_34745952 7.483 ENSMUST00000123823.1
ENSMUST00000136907.1
ENSMUST00000126181.1
Cald1


caldesmon 1


chr1_-_190170671 6.933 ENSMUST00000175916.1
Prox1
prospero-related homeobox 1
chr12_-_78980758 6.927 ENSMUST00000174072.1
Tmem229b
transmembrane protein 229B
chr1_-_190170178 6.817 ENSMUST00000177288.1
Prox1
prospero-related homeobox 1
chr16_+_43503607 6.714 ENSMUST00000126100.1
ENSMUST00000123047.1
ENSMUST00000156981.1
Zbtb20


zinc finger and BTB domain containing 20


chr16_+_43363855 6.569 ENSMUST00000156367.1
Zbtb20
zinc finger and BTB domain containing 20
chr2_+_65845833 6.508 ENSMUST00000053910.3
Csrnp3
cysteine-serine-rich nuclear protein 3
chr16_+_43247278 6.397 ENSMUST00000114691.1
ENSMUST00000079441.6
Zbtb20

zinc finger and BTB domain containing 20

chr3_+_156562141 6.313 ENSMUST00000175773.1
Negr1
neuronal growth regulator 1
chr4_+_101550411 6.297 ENSMUST00000094953.4
ENSMUST00000106933.1
Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr2_+_152081529 6.277 ENSMUST00000064061.3
Scrt2
scratch homolog 2, zinc finger protein (Drosophila)
chr18_+_37489465 6.252 ENSMUST00000055949.2
Pcdhb18
protocadherin beta 18
chr13_+_54371340 6.204 ENSMUST00000026985.8
Cplx2
complexin 2
chrX_-_88115632 6.094 ENSMUST00000113966.1
ENSMUST00000113964.1
Il1rapl1

interleukin 1 receptor accessory protein-like 1

chr3_-_80802789 5.918 ENSMUST00000107745.1
ENSMUST00000075316.4
Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chrX_-_70365052 5.901 ENSMUST00000101509.2
Ids
iduronate 2-sulfatase
chr4_-_53159885 5.870 ENSMUST00000030010.3
Abca1
ATP-binding cassette, sub-family A (ABC1), member 1
chr4_-_123527648 5.811 ENSMUST00000147228.1
Macf1
microtubule-actin crosslinking factor 1
chr3_+_156561950 5.803 ENSMUST00000041425.5
ENSMUST00000106065.1
Negr1

neuronal growth regulator 1

chr1_+_158362330 5.776 ENSMUST00000170718.1
Astn1
astrotactin 1
chr16_+_42907563 5.581 ENSMUST00000151244.1
ENSMUST00000114694.2
Zbtb20

zinc finger and BTB domain containing 20

chr4_-_82505749 5.506 ENSMUST00000107245.2
ENSMUST00000107246.1
Nfib

nuclear factor I/B

chr17_-_81649607 5.476 ENSMUST00000163680.2
ENSMUST00000086538.3
ENSMUST00000163123.1
Slc8a1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr2_+_32721055 5.418 ENSMUST00000074248.4
Sh2d3c
SH2 domain containing 3C
chr10_+_60106452 5.380 ENSMUST00000165024.2
Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr9_-_40346290 5.335 ENSMUST00000121357.1
Gramd1b
GRAM domain containing 1B
chr1_+_66386968 5.259 ENSMUST00000145419.1
Map2
microtubule-associated protein 2
chr17_-_37023349 5.167 ENSMUST00000102665.4
Mog
myelin oligodendrocyte glycoprotein
chr1_+_66175286 5.050 ENSMUST00000114017.1
ENSMUST00000114015.1
Map2

microtubule-associated protein 2

chr5_-_103211251 5.030 ENSMUST00000060871.5
ENSMUST00000112846.1
ENSMUST00000170792.1
ENSMUST00000112847.2
Mapk10



mitogen-activated protein kinase 10



chrX_+_41401304 4.953 ENSMUST00000076349.5
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr13_+_109685994 4.937 ENSMUST00000074103.5
Pde4d
phosphodiesterase 4D, cAMP specific
chr7_+_126950687 4.886 ENSMUST00000106333.1
Sez6l2
seizure related 6 homolog like 2
chrX_+_151198078 4.873 ENSMUST00000184730.1
ENSMUST00000184392.1
ENSMUST00000096285.4
Wnk3


WNK lysine deficient protein kinase 3


chr10_-_110000219 4.851 ENSMUST00000032719.7
Nav3
neuron navigator 3
chr7_+_126950518 4.847 ENSMUST00000106335.1
ENSMUST00000146017.1
Sez6l2

seizure related 6 homolog like 2

chr6_+_34746368 4.832 ENSMUST00000142716.1
Cald1
caldesmon 1
chrX_-_162565514 4.795 ENSMUST00000154424.1
Reps2
RALBP1 associated Eps domain containing protein 2
chr5_-_122049822 4.783 ENSMUST00000111752.3
Cux2
cut-like homeobox 2
chrX_+_136741821 4.778 ENSMUST00000089350.4
BC065397
cDNA sequence BC065397
chr14_-_124677089 4.723 ENSMUST00000095529.3
Fgf14
fibroblast growth factor 14
chr6_+_17749170 4.655 ENSMUST00000053148.7
ENSMUST00000115417.3
St7

suppression of tumorigenicity 7

chr2_+_121357714 4.594 ENSMUST00000125812.1
ENSMUST00000078222.2
ENSMUST00000125221.1
ENSMUST00000150271.1
Ckmt1



creatine kinase, mitochondrial 1, ubiquitous



chr1_-_56969827 4.569 ENSMUST00000176759.1
Satb2
special AT-rich sequence binding protein 2
chr8_+_57455898 4.534 ENSMUST00000034023.3
Scrg1
scrapie responsive gene 1
chr2_+_65845767 4.534 ENSMUST00000122912.1
Csrnp3
cysteine-serine-rich nuclear protein 3
chr9_-_55919605 4.513 ENSMUST00000037408.8
Scaper
S phase cyclin A-associated protein in the ER
chr10_+_60106198 4.493 ENSMUST00000121820.2
Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr3_+_51559973 4.455 ENSMUST00000180404.1
5031434O11Rik
RIKEN cDNA 5031434O11 gene
chr12_+_52699297 4.428 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chrX_-_73869804 4.338 ENSMUST00000066576.5
ENSMUST00000114430.1
L1cam

L1 cell adhesion molecule

chr13_+_105443693 4.296 ENSMUST00000022235.4
Htr1a
5-hydroxytryptamine (serotonin) receptor 1A
chr18_-_31317043 4.242 ENSMUST00000139924.1
ENSMUST00000153060.1
Rit2

Ras-like without CAAX 2

chr6_+_80018877 4.145 ENSMUST00000147663.1
ENSMUST00000128718.1
ENSMUST00000126005.1
ENSMUST00000133918.1
Lrrtm4



leucine rich repeat transmembrane neuronal 4



chr5_+_98180866 4.105 ENSMUST00000112959.1
Prdm8
PR domain containing 8
chr2_-_6722187 4.072 ENSMUST00000182657.1
Celf2
CUGBP, Elav-like family member 2
chr14_+_28504736 4.059 ENSMUST00000063465.4
Wnt5a
wingless-related MMTV integration site 5A
chr7_+_45699843 4.004 ENSMUST00000003360.7
Car11
carbonic anhydrase 11
chr6_-_118780324 3.990 ENSMUST00000112793.3
ENSMUST00000075591.6
ENSMUST00000078320.7
ENSMUST00000112790.2
Cacna1c



calcium channel, voltage-dependent, L type, alpha 1C subunit



chr16_+_43364145 3.939 ENSMUST00000148775.1
Zbtb20
zinc finger and BTB domain containing 20
chr9_+_64385675 3.887 ENSMUST00000068967.4
Megf11
multiple EGF-like-domains 11
chr7_+_67952817 3.879 ENSMUST00000005671.8
Igf1r
insulin-like growth factor I receptor
chr18_-_72351029 3.842 ENSMUST00000114943.3
Dcc
deleted in colorectal carcinoma
chr18_-_72351009 3.822 ENSMUST00000073379.5
Dcc
deleted in colorectal carcinoma
chr3_-_86548268 3.807 ENSMUST00000077524.3
Mab21l2
mab-21-like 2 (C. elegans)
chr16_+_41532999 3.795 ENSMUST00000099761.3
Lsamp
limbic system-associated membrane protein
chrX_+_56609751 3.770 ENSMUST00000144068.1
Slc9a6
solute carrier family 9 (sodium/hydrogen exchanger), member 6
chr14_+_27622433 3.758 ENSMUST00000090302.5
Erc2
ELKS/RAB6-interacting/CAST family member 2
chr2_-_29253001 3.753 ENSMUST00000071201.4
Ntng2
netrin G2
chr15_+_77084367 3.697 ENSMUST00000181870.1
1700109K24Rik
RIKEN cDNA 1700109K24 gene
chr1_-_56978534 3.647 ENSMUST00000177282.1
Satb2
special AT-rich sequence binding protein 2
chr12_-_90738438 3.590 ENSMUST00000082432.3
Dio2
deiodinase, iodothyronine, type II
chr6_-_137169710 3.563 ENSMUST00000117919.1
Rerg
RAS-like, estrogen-regulated, growth-inhibitor
chr12_-_64965496 3.549 ENSMUST00000021331.7
Klhl28
kelch-like 28
chr9_-_29963112 3.548 ENSMUST00000075069.4
Ntm
neurotrimin
chr14_+_66344369 3.545 ENSMUST00000118426.1
ENSMUST00000121955.1
ENSMUST00000120229.1
ENSMUST00000134440.1
Stmn4



stathmin-like 4



chr1_+_158362261 3.539 ENSMUST00000046110.9
Astn1
astrotactin 1
chr7_+_126950837 3.514 ENSMUST00000106332.1
Sez6l2
seizure related 6 homolog like 2
chr5_+_13398688 3.484 ENSMUST00000125629.1
Sema3a
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr8_-_67910911 3.458 ENSMUST00000093468.5
Psd3
pleckstrin and Sec7 domain containing 3
chr2_-_7396192 3.452 ENSMUST00000137733.2
Celf2
CUGBP, Elav-like family member 2
chrX_+_41401128 3.450 ENSMUST00000115103.2
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr11_+_87760533 3.425 ENSMUST00000039627.5
ENSMUST00000100644.3
Bzrap1

benzodiazepine receptor associated protein 1

chr6_-_137169678 3.376 ENSMUST00000119610.1
Rerg
RAS-like, estrogen-regulated, growth-inhibitor
chr2_+_4017727 3.363 ENSMUST00000177457.1
Frmd4a
FERM domain containing 4A
chr11_+_29463735 3.360 ENSMUST00000155854.1
Ccdc88a
coiled coil domain containing 88A
chr9_-_50693799 3.248 ENSMUST00000120622.1
Dixdc1
DIX domain containing 1
chr1_-_38664947 3.240 ENSMUST00000039827.7
ENSMUST00000027250.7
Aff3

AF4/FMR2 family, member 3

chr3_-_144202300 3.200 ENSMUST00000121796.1
ENSMUST00000121112.1
Lmo4

LIM domain only 4

chr5_+_57718021 3.172 ENSMUST00000094783.3
ENSMUST00000068110.7
Pcdh7

protocadherin 7

chr18_+_37341702 3.167 ENSMUST00000053037.3
Pcdhb7
protocadherin beta 7
chr4_+_144892813 3.125 ENSMUST00000105744.1
ENSMUST00000171001.1
Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr5_+_137553517 3.111 ENSMUST00000136088.1
ENSMUST00000139395.1
ENSMUST00000136565.1
ENSMUST00000149292.1
ENSMUST00000125489.1
Actl6b




actin-like 6B




chr1_-_133753681 3.043 ENSMUST00000125659.1
ENSMUST00000165602.2
ENSMUST00000048953.7
Atp2b4


ATPase, Ca++ transporting, plasma membrane 4


chr4_-_110290884 3.021 ENSMUST00000142722.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr17_+_21566988 3.001 ENSMUST00000088787.5
Zfp948
zinc finger protein 948
chr4_+_43401232 2.984 ENSMUST00000125399.1
Rusc2
RUN and SH3 domain containing 2
chr12_+_102948843 2.979 ENSMUST00000101099.5
Unc79
unc-79 homolog (C. elegans)
chr8_+_40354303 2.976 ENSMUST00000136835.1
Micu3
mitochondrial calcium uptake family, member 3
chr4_+_102760294 2.972 ENSMUST00000072481.5
ENSMUST00000156596.1
ENSMUST00000080728.6
ENSMUST00000106882.2
Sgip1



SH3-domain GRB2-like (endophilin) interacting protein 1



chr10_-_109010955 2.932 ENSMUST00000105276.1
ENSMUST00000064054.7
Syt1

synaptotagmin I

chr18_+_36952621 2.926 ENSMUST00000115661.2
Pcdha2
protocadherin alpha 2
chr14_+_56887795 2.860 ENSMUST00000022511.8
Zmym2
zinc finger, MYM-type 2
chr1_-_130729249 2.856 ENSMUST00000171479.1
Pfkfb2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr4_-_135494499 2.849 ENSMUST00000105856.2
Nipal3
NIPA-like domain containing 3
chr1_+_34160253 2.835 ENSMUST00000183302.1
Dst
dystonin
chr15_-_77153772 2.830 ENSMUST00000166610.1
ENSMUST00000111581.2
Rbfox2

RNA binding protein, fox-1 homolog (C. elegans) 2

chr17_-_68004075 2.809 ENSMUST00000024840.5
Arhgap28
Rho GTPase activating protein 28
chr18_+_37484955 2.809 ENSMUST00000053856.4
Pcdhb17
protocadherin beta 17
chr3_-_73056943 2.794 ENSMUST00000059407.7
Slitrk3
SLIT and NTRK-like family, member 3
chr6_+_92092369 2.787 ENSMUST00000113463.1
Nr2c2
nuclear receptor subfamily 2, group C, member 2
chr6_+_149408973 2.786 ENSMUST00000086829.4
ENSMUST00000111513.2
Bicd1

bicaudal D homolog 1 (Drosophila)

chrX_+_13071470 2.781 ENSMUST00000169594.2
Usp9x
ubiquitin specific peptidase 9, X chromosome
chr3_+_8509477 2.766 ENSMUST00000029002.7
Stmn2
stathmin-like 2
chr9_+_64385626 2.728 ENSMUST00000093829.2
ENSMUST00000118485.1
ENSMUST00000164113.1
Megf11


multiple EGF-like-domains 11


chr16_+_44173271 2.727 ENSMUST00000088356.4
ENSMUST00000169582.1
Gm608

predicted gene 608

chrX_+_93675088 2.700 ENSMUST00000045898.3
Pcyt1b
phosphate cytidylyltransferase 1, choline, beta isoform
chr4_+_133369702 2.689 ENSMUST00000030669.7
Slc9a1
solute carrier family 9 (sodium/hydrogen exchanger), member 1
chr2_+_3713449 2.672 ENSMUST00000027965.4
Fam107b
family with sequence similarity 107, member B
chr17_-_91088726 2.663 ENSMUST00000072671.7
ENSMUST00000174331.1
ENSMUST00000161402.3
ENSMUST00000054059.8
Nrxn1



neurexin I



chr2_-_114013619 2.639 ENSMUST00000090275.4
Gjd2
gap junction protein, delta 2
chr12_-_83439910 2.626 ENSMUST00000177801.1
Dpf3
D4, zinc and double PHD fingers, family 3
chr11_+_19924403 2.618 ENSMUST00000093298.5
Spred2
sprouty-related, EVH1 domain containing 2
chr4_+_116221590 2.595 ENSMUST00000147292.1
Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr13_+_42866247 2.592 ENSMUST00000131942.1
Phactr1
phosphatase and actin regulator 1
chr11_-_69605829 2.565 ENSMUST00000047889.6
Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr8_+_128359065 2.564 ENSMUST00000026917.8
Nrp1
neuropilin 1
chr4_+_144893077 2.522 ENSMUST00000154208.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr2_-_6721890 2.516 ENSMUST00000114927.2
Celf2
CUGBP, Elav-like family member 2
chr5_-_70842617 2.512 ENSMUST00000031119.1
Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr1_+_66321708 2.508 ENSMUST00000114013.1
Map2
microtubule-associated protein 2
chr7_+_49246812 2.507 ENSMUST00000184945.1
Nav2
neuron navigator 2
chr4_+_144893127 2.507 ENSMUST00000142808.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr2_+_68861564 2.504 ENSMUST00000176018.1
Cers6
ceramide synthase 6
chr7_-_37770757 2.485 ENSMUST00000176680.1
Zfp536
zinc finger protein 536
chr10_+_39612934 2.474 ENSMUST00000019987.6
Traf3ip2
TRAF3 interacting protein 2
chr9_-_112234956 2.448 ENSMUST00000162097.1
ENSMUST00000159055.1
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr17_+_21657582 2.448 ENSMUST00000039726.7
3110052M02Rik
RIKEN cDNA 3110052M02 gene
chr9_-_75599124 2.435 ENSMUST00000098552.2
Tmod2
tropomodulin 2
chr10_-_95415283 2.432 ENSMUST00000119917.1
Socs2
suppressor of cytokine signaling 2
chrX_+_150547375 2.416 ENSMUST00000066337.6
ENSMUST00000112715.1
Alas2

aminolevulinic acid synthase 2, erythroid

chr2_-_33942111 2.416 ENSMUST00000130988.1
ENSMUST00000127936.1
ENSMUST00000134271.1
Gm13403


predicted gene 13403


chr1_-_56971762 2.414 ENSMUST00000114415.3
Satb2
special AT-rich sequence binding protein 2
chrX_+_56609843 2.410 ENSMUST00000077741.5
ENSMUST00000114784.2
Slc9a6

solute carrier family 9 (sodium/hydrogen exchanger), member 6

chr7_-_31042078 2.408 ENSMUST00000162116.1
ENSMUST00000159924.1
ENSMUST00000159753.1
ENSMUST00000160689.1
ENSMUST00000162733.1
ENSMUST00000162087.1
ENSMUST00000009831.7
Fxyd5






FXYD domain-containing ion transport regulator 5






chr11_+_101246405 2.404 ENSMUST00000122006.1
ENSMUST00000151830.1
Ramp2

receptor (calcitonin) activity modifying protein 2

chr7_+_3390629 2.401 ENSMUST00000182222.1
Cacng8
calcium channel, voltage-dependent, gamma subunit 8
chr15_+_82274935 2.398 ENSMUST00000023095.6
Sept3
septin 3
chrX_-_95166307 2.397 ENSMUST00000113873.2
ENSMUST00000113876.2
ENSMUST00000113885.1
ENSMUST00000113883.1
ENSMUST00000182001.1
ENSMUST00000113882.1
ENSMUST00000113878.1
ENSMUST00000182562.1
Arhgef9







CDC42 guanine nucleotide exchange factor (GEF) 9







chr18_+_37477768 2.387 ENSMUST00000051442.5
Pcdhb16
protocadherin beta 16
chr18_-_43393346 2.381 ENSMUST00000025379.7
Dpysl3
dihydropyrimidinase-like 3
chr11_+_57011798 2.376 ENSMUST00000036315.9
Gria1
glutamate receptor, ionotropic, AMPA1 (alpha 1)
chr10_-_62880014 2.358 ENSMUST00000050826.7
Tet1
tet methylcytosine dioxygenase 1
chr7_+_46397648 2.338 ENSMUST00000160433.1
Kcnc1
potassium voltage gated channel, Shaw-related subfamily, member 1
chr17_-_50094277 2.292 ENSMUST00000113195.1
Rftn1
raftlin lipid raft linker 1
chr15_-_43869993 2.280 ENSMUST00000067469.4
Tmem74
transmembrane protein 74
chr1_+_177445660 2.276 ENSMUST00000077225.6
Zbtb18
zinc finger and BTB domain containing 18
chr15_-_99820072 2.265 ENSMUST00000109024.2
Lima1
LIM domain and actin binding 1
chr18_+_37294840 2.243 ENSMUST00000056522.3
Pcdhb2
protocadherin beta 2
chr10_-_29144194 2.239 ENSMUST00000070359.2
Gm9996
predicted gene 9996
chr14_+_66344296 2.238 ENSMUST00000152093.1
ENSMUST00000074523.6
Stmn4

stathmin-like 4

chr11_+_69364010 2.227 ENSMUST00000166700.1
Gm17305
predicted gene, 17305
chr11_+_60777525 2.224 ENSMUST00000056907.6
ENSMUST00000102667.3
Smcr8

Smith-Magenis syndrome chromosome region, candidate 8 homolog (human)

chr13_+_40917626 2.222 ENSMUST00000067778.6
Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr11_-_94297067 2.222 ENSMUST00000132623.2
Luc7l3
LUC7-like 3 (S. cerevisiae)
chr18_+_23415400 2.221 ENSMUST00000115832.2
ENSMUST00000047954.7
Dtna

dystrobrevin alpha

chr17_+_21491256 2.205 ENSMUST00000076664.6
Zfp53
zinc finger protein 53
chr3_-_122619442 2.192 ENSMUST00000162947.1
Fnbp1l
formin binding protein 1-like
chr12_+_109545390 2.189 ENSMUST00000146701.1
Meg3
maternally expressed 3
chrX_+_134404543 2.187 ENSMUST00000113228.1
ENSMUST00000153424.1
Drp2

dystrophin related protein 2

chrX_+_166344692 2.184 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
Gpm6b





glycoprotein m6b





chr7_-_35802968 2.164 ENSMUST00000061586.4
Zfp507
zinc finger protein 507
chr2_+_158666690 2.153 ENSMUST00000103116.3
Ppp1r16b
protein phosphatase 1, regulatory (inhibitor) subunit 16B
chr17_+_91088493 2.148 ENSMUST00000095183.1
Gm10308
predicted gene 10308
chr10_-_109009055 2.137 ENSMUST00000156979.1
Syt1
synaptotagmin I
chr1_-_22315792 2.136 ENSMUST00000164877.1
Rims1
regulating synaptic membrane exocytosis 1
chr5_-_99729039 2.121 ENSMUST00000146396.1
ENSMUST00000161148.1
ENSMUST00000161516.1
A930011G23Rik


RIKEN cDNA A930011G23 gene


chr1_+_118389058 2.108 ENSMUST00000049404.6
ENSMUST00000070989.7
ENSMUST00000165223.1
ENSMUST00000178710.1
Clasp1



CLIP associating protein 1



chr12_+_73286779 2.097 ENSMUST00000140523.1
Slc38a6
solute carrier family 38, member 6
chr11_+_97798995 2.089 ENSMUST00000143571.1
Lasp1
LIM and SH3 protein 1
chr12_-_67221221 2.089 ENSMUST00000178814.1
ENSMUST00000179345.2
Mdga2
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
MAM domain-containing glycosylphosphatidylinositol anchor protein 2
chr13_+_43615950 2.079 ENSMUST00000161817.1
Rnf182
ring finger protein 182
chr1_+_15287259 2.075 ENSMUST00000175681.1
Kcnb2
potassium voltage gated channel, Shab-related subfamily, member 2

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 15.0 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
3.8 15.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
3.2 12.8 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
2.6 7.7 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
2.0 10.1 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
1.9 9.3 GO:2000481 positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
1.6 8.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
1.6 4.9 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
1.6 4.7 GO:0060067 cervix development(GO:0060067)
1.5 6.1 GO:0097105 presynaptic membrane assembly(GO:0097105)
1.5 7.6 GO:0090273 regulation of somatostatin secretion(GO:0090273)
1.4 12.4 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
1.3 5.0 GO:0097393 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
1.2 5.0 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
1.2 13.4 GO:0015721 bile acid and bile salt transport(GO:0015721)
1.2 6.0 GO:0021856 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
1.2 4.8 GO:1900736 regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
1.2 9.3 GO:0007158 neuron cell-cell adhesion(GO:0007158)
1.1 10.2 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
1.1 6.7 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
1.1 10.7 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
1.1 2.1 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
1.0 6.3 GO:0072318 clathrin coat disassembly(GO:0072318)
1.0 1.0 GO:0009247 glycolipid biosynthetic process(GO:0009247)
1.0 4.0 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
1.0 3.9 GO:0044849 estrous cycle(GO:0044849) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
1.0 2.9 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.9 2.7 GO:0002331 pre-B cell allelic exclusion(GO:0002331) signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434) regulation of microglial cell activation(GO:1903978) telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.9 1.7 GO:0070305 response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321)
0.8 5.0 GO:0007258 JUN phosphorylation(GO:0007258)
0.8 7.4 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.8 31.5 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.7 8.2 GO:0042572 retinol metabolic process(GO:0042572)
0.7 2.2 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.7 4.4 GO:0097646 dimeric G-protein coupled receptor signaling pathway(GO:0038042) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.7 5.1 GO:0005513 detection of calcium ion(GO:0005513)
0.7 2.8 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.7 2.8 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.7 2.8 GO:0036438 maintenance of lens transparency(GO:0036438)
0.7 2.8 GO:0046684 response to pyrethroid(GO:0046684)
0.7 2.7 GO:0097104 postsynaptic membrane assembly(GO:0097104) neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.7 1.3 GO:2000111 positive regulation of macrophage apoptotic process(GO:2000111)
0.7 6.5 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.6 2.6 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.6 3.1 GO:0033227 dsRNA transport(GO:0033227)
0.6 2.5 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.6 3.7 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.6 4.9 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.6 3.6 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.6 1.8 GO:0003195 tricuspid valve formation(GO:0003195)
0.6 4.1 GO:1901629 regulation of presynaptic membrane organization(GO:1901629)
0.6 5.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.6 13.2 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.6 23.9 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
0.6 2.8 GO:0060690 epithelial cell differentiation involved in salivary gland development(GO:0060690)
0.6 7.3 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.6 1.1 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.5 2.7 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.5 2.2 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.5 2.1 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.5 2.1 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.5 1.0 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.5 1.6 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.5 3.6 GO:0019336 phenol-containing compound catabolic process(GO:0019336)
0.5 2.5 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.5 1.5 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.5 4.4 GO:0071420 cellular response to histamine(GO:0071420)
0.5 4.3 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.5 1.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.5 9.5 GO:0007019 microtubule depolymerization(GO:0007019)
0.5 2.4 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.5 0.9 GO:0090218 positive regulation of lipid kinase activity(GO:0090218)
0.5 2.3 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.5 19.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.5 1.9 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.4 9.8 GO:0002076 osteoblast development(GO:0002076)
0.4 6.6 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.4 3.1 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.4 1.8 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.4 0.9 GO:0002730 regulation of dendritic cell cytokine production(GO:0002730)
0.4 2.1 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.4 1.2 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.4 1.2 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.4 0.8 GO:0097476 spinal cord motor neuron migration(GO:0097476)
0.4 2.0 GO:0035063 nuclear speck organization(GO:0035063)
0.4 0.8 GO:2000821 regulation of grooming behavior(GO:2000821)
0.4 0.8 GO:1903275 positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278)
0.4 0.4 GO:2000426 negative regulation of apoptotic cell clearance(GO:2000426)
0.4 0.8 GO:0008594 photoreceptor cell morphogenesis(GO:0008594)
0.4 2.8 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.4 1.2 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.4 29.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.4 1.5 GO:0042636 negative regulation of hair cycle(GO:0042636) negative regulation of hair follicle development(GO:0051799)
0.4 1.5 GO:0070327 thyroid hormone transport(GO:0070327)
0.4 1.4 GO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300)
0.4 1.1 GO:0048686 regulation of sprouting of injured axon(GO:0048686) positive regulation of sprouting of injured axon(GO:0048687) regulation of axon extension involved in regeneration(GO:0048690) positive regulation of axon extension involved in regeneration(GO:0048691)
0.4 1.1 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.3 3.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.3 1.7 GO:0086023 adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.3 13.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.3 3.0 GO:0048149 behavioral response to ethanol(GO:0048149)
0.3 1.0 GO:1904170 interleukin-1 alpha secretion(GO:0050703) regulation of bleb assembly(GO:1904170)
0.3 1.0 GO:0019085 early viral transcription(GO:0019085)
0.3 6.1 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.3 2.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.3 1.9 GO:0060012 synaptic transmission, glycinergic(GO:0060012) cellular response to ethanol(GO:0071361)
0.3 0.9 GO:0032055 negative regulation of translation in response to stress(GO:0032055)
0.3 1.2 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.3 0.9 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.3 1.8 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.3 4.2 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.3 6.9 GO:0035641 locomotory exploration behavior(GO:0035641)
0.3 0.6 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.3 3.8 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.3 1.5 GO:0051012 microtubule sliding(GO:0051012)
0.3 5.5 GO:0035640 exploration behavior(GO:0035640)
0.3 1.2 GO:0070459 prolactin secretion(GO:0070459)
0.3 0.6 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.3 1.4 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.3 2.0 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.3 0.8 GO:0001543 ovarian follicle rupture(GO:0001543)
0.3 12.8 GO:0001919 regulation of receptor recycling(GO:0001919)
0.3 1.7 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.3 0.8 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.3 0.8 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.3 0.5 GO:0035937 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.3 0.8 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.3 2.9 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.3 0.8 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.3 1.6 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.3 1.3 GO:0097167 circadian regulation of translation(GO:0097167)
0.3 0.8 GO:1904245 regulation of polynucleotide adenylyltransferase activity(GO:1904245)
0.3 0.3 GO:0010819 regulation of T cell chemotaxis(GO:0010819)
0.3 1.8 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.3 0.8 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.3 2.9 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.3 1.5 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.3 3.3 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.3 1.3 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.3 1.0 GO:0050904 diapedesis(GO:0050904) regulation of leukocyte tethering or rolling(GO:1903236)
0.2 5.0 GO:0007614 short-term memory(GO:0007614)
0.2 0.7 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.2 0.5 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.2 0.7 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.2 0.5 GO:0035826 rubidium ion transport(GO:0035826)
0.2 1.5 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.2 0.7 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.2 1.0 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.2 4.3 GO:0015693 magnesium ion transport(GO:0015693)
0.2 0.9 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.2 1.6 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 1.6 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.2 1.1 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.2 0.7 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.2 0.9 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.2 1.5 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.2 4.2 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.2 1.3 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.2 2.4 GO:0046958 nonassociative learning(GO:0046958)
0.2 1.5 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.2 1.1 GO:0051013 microtubule severing(GO:0051013)
0.2 0.4 GO:2000790 regulation of mesenchymal cell proliferation involved in lung development(GO:2000790) negative regulation of mesenchymal cell proliferation involved in lung development(GO:2000791)
0.2 1.7 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.2 0.6 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.2 2.3 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.2 1.7 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.2 1.3 GO:0014842 regulation of skeletal muscle satellite cell proliferation(GO:0014842) regulation of skeletal muscle cell proliferation(GO:0014857)
0.2 1.2 GO:0098964 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.2 3.3 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.2 10.2 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.2 3.6 GO:0048268 clathrin coat assembly(GO:0048268)
0.2 0.8 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.2 1.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.2 0.8 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.2 0.4 GO:0015793 glycerol transport(GO:0015793)
0.2 2.9 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.2 0.6 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.2 3.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.2 1.0 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.2 1.0 GO:0003105 negative regulation of glomerular filtration(GO:0003105)
0.2 0.6 GO:0014874 response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.2 1.1 GO:0016198 axon choice point recognition(GO:0016198)
0.2 3.2 GO:0042659 regulation of cell fate specification(GO:0042659)
0.2 1.1 GO:0042045 epithelial fluid transport(GO:0042045)
0.2 2.0 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) cellular response to magnesium ion(GO:0071286) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 1.1 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.2 12.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.2 0.7 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.2 0.7 GO:0071442 regulation of histone H3-K14 acetylation(GO:0071440) positive regulation of histone H3-K14 acetylation(GO:0071442)
0.2 0.7 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.2 0.5 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.2 2.2 GO:1900746 regulation of vascular endothelial growth factor signaling pathway(GO:1900746)
0.2 1.0 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.2 1.0 GO:0002674 negative regulation of acute inflammatory response(GO:0002674)
0.2 0.5 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.2 0.5 GO:2000314 negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.2 0.5 GO:0002578 negative regulation of antigen processing and presentation(GO:0002578)
0.2 2.2 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.2 4.0 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.2 0.6 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.1 0.6 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 1.6 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.4 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.1 13.7 GO:0007416 synapse assembly(GO:0007416)
0.1 0.4 GO:0019858 cytosine metabolic process(GO:0019858)
0.1 0.8 GO:0032196 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) transposition(GO:0032196)
0.1 0.4 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.1 0.8 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 2.3 GO:0002115 store-operated calcium entry(GO:0002115)
0.1 1.0 GO:0043084 penile erection(GO:0043084)
0.1 0.7 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 1.1 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.1 4.1 GO:2001222 regulation of neuron migration(GO:2001222)
0.1 3.2 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.1 1.6 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 1.3 GO:0048520 positive regulation of behavior(GO:0048520)
0.1 0.8 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.1 4.8 GO:0035150 regulation of tube size(GO:0035150) regulation of blood vessel size(GO:0050880)
0.1 3.9 GO:0043242 negative regulation of protein complex disassembly(GO:0043242)
0.1 1.6 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.1 0.4 GO:0072382 minus-end-directed vesicle transport along microtubule(GO:0072382) regulation of metaphase plate congression(GO:0090235)
0.1 0.1 GO:0007521 muscle cell fate determination(GO:0007521)
0.1 0.1 GO:0070572 positive regulation of neuron projection regeneration(GO:0070572)
0.1 0.4 GO:0030473 cell motility involved in cerebral cortex radial glia guided migration(GO:0021814) modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration(GO:0021815) nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473) nuclear migration along microfilament(GO:0031022)
0.1 3.7 GO:0043113 receptor clustering(GO:0043113)
0.1 0.2 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 0.5 GO:0071105 response to interleukin-11(GO:0071105) osteoclast fusion(GO:0072675)
0.1 1.1 GO:0006020 inositol metabolic process(GO:0006020)
0.1 9.1 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.1 0.8 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 1.1 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.1 0.7 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.1 1.1 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 3.0 GO:0010842 retina layer formation(GO:0010842)
0.1 0.7 GO:0090383 phagosome acidification(GO:0090383)
0.1 0.3 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 1.8 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.1 0.7 GO:2000169 regulation of peptidyl-cysteine S-nitrosylation(GO:2000169)
0.1 0.7 GO:0002524 hypersensitivity(GO:0002524)
0.1 1.0 GO:0008585 female gonad development(GO:0008585)
0.1 0.5 GO:0044805 late nucleophagy(GO:0044805)
0.1 0.8 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 0.4 GO:0046549 retinal cone cell development(GO:0046549)
0.1 0.3 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.1 2.2 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.1 1.5 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.1 0.4 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.9 GO:0001881 receptor recycling(GO:0001881)
0.1 0.8 GO:0030953 astral microtubule organization(GO:0030953)
0.1 0.5 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.1 0.5 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 1.8 GO:0016486 peptide hormone processing(GO:0016486)
0.1 0.5 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 3.0 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.1 0.9 GO:0048194 Golgi vesicle budding(GO:0048194)
0.1 1.4 GO:0001553 luteinization(GO:0001553)
0.1 0.4 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.1 0.9 GO:0035428 hexose transmembrane transport(GO:0035428)
0.1 0.7 GO:0060179 male mating behavior(GO:0060179)
0.1 1.9 GO:0016052 carbohydrate catabolic process(GO:0016052)
0.1 0.4 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.1 1.2 GO:0060117 auditory receptor cell development(GO:0060117)
0.1 1.0 GO:0070842 aggresome assembly(GO:0070842)
0.1 3.2 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.1 0.4 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 1.9 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 0.6 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 1.5 GO:0002052 positive regulation of neuroblast proliferation(GO:0002052)
0.1 1.5 GO:0009072 aromatic amino acid family metabolic process(GO:0009072)
0.1 0.3 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.1 1.1 GO:0006828 manganese ion transport(GO:0006828)
0.1 1.3 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.4 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 1.4 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.1 0.6 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 0.3 GO:0048162 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.1 0.9 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 0.3 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.1 1.9 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 0.5 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.1 0.2 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.1 0.6 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 3.4 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.1 0.7 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.6 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 0.2 GO:0035095 behavioral response to nicotine(GO:0035095)
0.1 0.2 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.1 0.3 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 0.6 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.1 2.2 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.1 1.5 GO:0002335 mature B cell differentiation(GO:0002335)
0.1 0.4 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.4 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.1 0.2 GO:0010958 regulation of amino acid import(GO:0010958)
0.1 0.2 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.1 0.9 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.1 0.2 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.1 0.4 GO:0030033 microvillus assembly(GO:0030033)
0.1 0.5 GO:0099612 protein localization to axon(GO:0099612)
0.1 0.7 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.1 0.2 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.1 0.2 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.1 1.7 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 0.8 GO:0006903 vesicle targeting(GO:0006903)
0.1 0.6 GO:0071625 vocalization behavior(GO:0071625)
0.1 0.5 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1 0.3 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.1 0.4 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.1 0.5 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.1 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 0.2 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.5 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.4 GO:0048102 autophagic cell death(GO:0048102)
0.1 0.4 GO:0060903 regulation of meiosis I(GO:0060631) positive regulation of meiosis I(GO:0060903)
0.1 0.5 GO:0035608 protein deglutamylation(GO:0035608)
0.1 1.0 GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway(GO:0031664)
0.1 0.4 GO:0071941 nitrogen cycle metabolic process(GO:0071941)
0.1 0.2 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.1 0.9 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.1 0.2 GO:1901678 iron coordination entity transport(GO:1901678)
0.1 1.2 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.1 0.4 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.1 2.5 GO:0034605 cellular response to heat(GO:0034605)
0.1 1.3 GO:0019835 cytolysis(GO:0019835)
0.1 2.0 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 1.9 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.1 1.1 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.1 0.4 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.1 0.3 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 0.2 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.1 0.9 GO:0001541 ovarian follicle development(GO:0001541)
0.1 0.3 GO:1902414 protein localization to cell junction(GO:1902414)
0.1 0.1 GO:0098705 plasma membrane copper ion transport(GO:0015679) copper ion import across plasma membrane(GO:0098705) copper ion import into cell(GO:1902861)
0.1 0.4 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.3 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.1 0.8 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.3 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 0.2 GO:0061386 closure of optic fissure(GO:0061386)
0.1 0.5 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1 0.9 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 0.3 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.1 0.5 GO:0036120 response to platelet-derived growth factor(GO:0036119) cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.1 1.1 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 4.7 GO:0071805 potassium ion transmembrane transport(GO:0071805)
0.0 1.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.6 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.3 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.1 GO:0036233 glycine import(GO:0036233)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.4 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:0006532 aspartate biosynthetic process(GO:0006532)
0.0 0.7 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.5 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.2 GO:0051900 regulation of mitochondrial depolarization(GO:0051900)
0.0 0.7 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.3 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.0 GO:0033578 protein glycosylation in Golgi(GO:0033578)
0.0 0.2 GO:1901978 positive regulation of cell cycle checkpoint(GO:1901978)
0.0 0.6 GO:0032094 response to food(GO:0032094)
0.0 0.3 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.2 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.1 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 3.0 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.5 GO:0015813 L-glutamate transport(GO:0015813)
0.0 0.7 GO:0014911 positive regulation of smooth muscle cell migration(GO:0014911)
0.0 2.3 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.8 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.6 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.1 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.5 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.2 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.6 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.5 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 1.3 GO:0055013 cardiac muscle cell development(GO:0055013)
0.0 0.5 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.3 GO:0036506 maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 1.2 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.4 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.0 0.2 GO:0010155 regulation of proton transport(GO:0010155)
0.0 0.4 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.9 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.1 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.0 1.5 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.4 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.1 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.4 GO:0044804 nucleophagy(GO:0044804)
0.0 0.4 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.3 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.9 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 0.9 GO:0007091 metaphase/anaphase transition of mitotic cell cycle(GO:0007091) metaphase/anaphase transition of cell cycle(GO:0044784)
0.0 0.5 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.6 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.1 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.3 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.4 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.3 GO:0010225 response to UV-C(GO:0010225)
0.0 0.4 GO:0001782 B cell homeostasis(GO:0001782)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.3 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.2 GO:0015838 amino-acid betaine transport(GO:0015838)
0.0 0.2 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.1 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.2 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 0.1 GO:0035094 response to nicotine(GO:0035094)
0.0 0.3 GO:0014887 cardiac muscle adaptation(GO:0014887)
0.0 0.2 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 0.1 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.2 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.0 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.2 GO:0030813 positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.0 0.6 GO:0007088 regulation of mitotic nuclear division(GO:0007088)
0.0 1.0 GO:0098656 anion transmembrane transport(GO:0098656)
0.0 0.4 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 0.1 GO:0031111 negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.0 0.1 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 1.0 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.3 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.2 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.3 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 1.3 GO:0000725 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0 0.3 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 0.1 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
0.0 0.5 GO:0045931 positive regulation of mitotic cell cycle(GO:0045931)
0.0 0.1 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.0 1.0 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.3 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.2 GO:0033233 regulation of protein sumoylation(GO:0033233) positive regulation of protein sumoylation(GO:0033235)
0.0 0.0 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 23.6 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
1.7 15.0 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
1.6 6.2 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
1.5 13.5 GO:0030478 actin cap(GO:0030478)
1.4 8.6 GO:0044308 axonal spine(GO:0044308)
1.3 5.0 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
1.1 4.2 GO:0097447 dendritic tree(GO:0097447)
0.9 4.4 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.8 15.1 GO:0032279 asymmetric synapse(GO:0032279)
0.8 17.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.8 12.1 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.8 1.5 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
0.7 2.1 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.7 3.6 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.7 2.8 GO:0031673 H zone(GO:0031673)
0.7 2.1 GO:0043512 inhibin A complex(GO:0043512)
0.7 3.5 GO:0030314 junctional membrane complex(GO:0030314)
0.7 7.3 GO:0032584 growth cone membrane(GO:0032584)
0.7 13.0 GO:0016514 SWI/SNF complex(GO:0016514)
0.6 1.9 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.6 2.4 GO:0099569 presynaptic cytoskeleton(GO:0099569)
0.6 5.3 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.6 24.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.6 4.0 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.6 1.7 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.5 2.1 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.5 1.5 GO:1903095 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.5 2.0 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.5 1.9 GO:0008091 spectrin(GO:0008091)
0.5 4.2 GO:0044294 dendritic growth cone(GO:0044294)
0.5 2.8 GO:0097443 sorting endosome(GO:0097443)
0.5 6.5 GO:0043203 axon hillock(GO:0043203)
0.4 3.2 GO:0033648 host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.4 2.6 GO:0071565 nBAF complex(GO:0071565)
0.4 1.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.4 2.5 GO:0033503 HULC complex(GO:0033503)
0.3 4.3 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.3 6.7 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.3 5.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.3 0.8 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.3 1.4 GO:0070876 SOSS complex(GO:0070876)
0.3 0.8 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.3 0.8 GO:0016939 kinesin II complex(GO:0016939)
0.3 1.6 GO:0044292 dendrite terminus(GO:0044292)
0.3 1.3 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.3 4.7 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.3 0.5 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.3 1.6 GO:0061689 tricellular tight junction(GO:0061689)
0.3 1.0 GO:0031983 vesicle lumen(GO:0031983)
0.3 3.6 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.2 2.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.2 0.2 GO:1904949 ATPase complex(GO:1904949)
0.2 2.6 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.2 0.9 GO:0044307 dendritic branch(GO:0044307)
0.2 0.7 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.2 6.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.2 5.0 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.2 1.5 GO:0005883 neurofilament(GO:0005883)
0.2 0.8 GO:1990111 spermatoproteasome complex(GO:1990111)
0.2 5.6 GO:0034707 chloride channel complex(GO:0034707)
0.2 2.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 1.7 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 47.9 GO:0045211 postsynaptic membrane(GO:0045211)
0.2 1.8 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2 5.2 GO:0030673 axolemma(GO:0030673)
0.2 4.3 GO:0042734 presynaptic membrane(GO:0042734)
0.2 1.1 GO:0097165 nuclear stress granule(GO:0097165)
0.2 1.7 GO:0070545 PeBoW complex(GO:0070545)
0.2 5.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.2 22.1 GO:0005923 bicellular tight junction(GO:0005923)
0.2 1.1 GO:0031527 filopodium membrane(GO:0031527)
0.2 2.2 GO:0042788 polysomal ribosome(GO:0042788)
0.2 0.9 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2 5.2 GO:0001917 photoreceptor inner segment(GO:0001917)
0.2 2.0 GO:1904115 axon cytoplasm(GO:1904115)
0.1 1.5 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.6 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.1 1.9 GO:0042581 specific granule(GO:0042581)
0.1 0.7 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 2.7 GO:0097228 sperm principal piece(GO:0097228)
0.1 0.5 GO:1990769 proximal neuron projection(GO:1990769)
0.1 0.8 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.1 1.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 8.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 0.6 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 22.9 GO:0060076 excitatory synapse(GO:0060076)
0.1 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 0.6 GO:0030891 VCB complex(GO:0030891)
0.1 1.4 GO:0000242 pericentriolar material(GO:0000242)
0.1 12.4 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 2.2 GO:0071004 U2-type prespliceosome(GO:0071004)
0.1 0.5 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553) lumenal side of membrane(GO:0098576)
0.1 0.7 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.1 0.6 GO:0070852 cell body fiber(GO:0070852)
0.1 2.1 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 0.8 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.6 GO:0070695 FHF complex(GO:0070695)
0.1 0.7 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 2.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.4 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 0.8 GO:0070578 RISC-loading complex(GO:0070578)
0.1 0.8 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 0.8 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1 2.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 3.9 GO:1990391 DNA repair complex(GO:1990391)
0.1 3.8 GO:0045171 intercellular bridge(GO:0045171)
0.1 3.4 GO:0005801 cis-Golgi network(GO:0005801)
0.1 0.6 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 1.2 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.5 GO:0005638 lamin filament(GO:0005638)
0.1 4.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.5 GO:0042629 mast cell granule(GO:0042629)
0.1 0.6 GO:0097227 sperm annulus(GO:0097227)
0.1 1.8 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 4.9 GO:0035097 histone methyltransferase complex(GO:0035097)
0.1 1.7 GO:0099738 cell cortex region(GO:0099738)
0.1 0.6 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 4.9 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.6 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 0.5 GO:0097225 sperm midpiece(GO:0097225)
0.1 2.6 GO:0005802 trans-Golgi network(GO:0005802)
0.1 2.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 0.4 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 7.0 GO:0030427 site of polarized growth(GO:0030427)
0.0 0.7 GO:0031985 Golgi cisterna(GO:0031985)
0.0 2.5 GO:0043204 perikaryon(GO:0043204)
0.0 1.1 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 4.1 GO:0016605 PML body(GO:0016605)
0.0 1.5 GO:0044309 neuron spine(GO:0044309)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 2.1 GO:0005776 autophagosome(GO:0005776)
0.0 0.3 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 28.4 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 1.2 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 9.3 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.5 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.2 GO:0097208 alveolar lamellar body(GO:0097208)
0.0 0.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.8 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 2.9 GO:0044306 neuron projection terminus(GO:0044306)
0.0 0.3 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 2.7 GO:0030027 lamellipodium(GO:0030027)
0.0 0.5 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 1.1 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.4 GO:1990635 proximal dendrite(GO:1990635)
0.0 1.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.3 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.4 GO:0097060 synaptic membrane(GO:0097060)
0.0 0.8 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.2 GO:0097470 ribbon synapse(GO:0097470)
0.0 1.0 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.7 GO:0005811 lipid particle(GO:0005811)
0.0 0.7 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 2.3 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.5 GO:0031201 SNARE complex(GO:0031201)
0.0 1.4 GO:0042641 actomyosin(GO:0042641)
0.0 0.5 GO:0005902 microvillus(GO:0005902)
0.0 56.6 GO:0016021 integral component of membrane(GO:0016021)
0.0 0.4 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.2 GO:0002102 podosome(GO:0002102)
0.0 0.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.3 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.8 GO:0005643 nuclear pore(GO:0005643)
0.0 0.3 GO:0005882 intermediate filament(GO:0005882)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 14.0 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
2.8 22.4 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
2.6 10.3 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
2.4 16.7 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
2.0 5.9 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
1.8 5.3 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
1.5 5.9 GO:0004111 creatine kinase activity(GO:0004111)
1.4 5.5 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
1.4 4.1 GO:0005110 frizzled-2 binding(GO:0005110)
1.3 9.0 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
1.3 7.7 GO:0005042 netrin receptor activity(GO:0005042)
1.3 5.1 GO:0030348 syntaxin-3 binding(GO:0030348)
1.3 10.1 GO:0015386 potassium:proton antiporter activity(GO:0015386)
1.3 5.0 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
1.3 15.0 GO:0050693 LBD domain binding(GO:0050693)
1.3 15.0 GO:0097109 neuroligin family protein binding(GO:0097109)
1.2 16.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.9 2.8 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.9 2.7 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.9 4.4 GO:0097643 amylin receptor activity(GO:0097643)
0.8 3.3 GO:0001639 PLC activating G-protein coupled glutamate receptor activity(GO:0001639) G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.8 4.2 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.8 1.6 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.8 1.6 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.8 2.4 GO:0016748 succinyltransferase activity(GO:0016748)
0.8 2.4 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.8 2.4 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.8 2.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.8 6.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.7 5.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.7 5.0 GO:0015616 DNA translocase activity(GO:0015616)
0.7 4.2 GO:0033691 sialic acid binding(GO:0033691)
0.7 4.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.6 2.5 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.6 3.0 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.6 3.6 GO:0043559 insulin binding(GO:0043559)
0.6 11.9 GO:0031402 sodium ion binding(GO:0031402)
0.6 0.6 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.6 4.5 GO:0032051 clathrin light chain binding(GO:0032051)
0.6 11.1 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.6 5.0 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.5 1.6 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.5 2.7 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.5 4.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.5 1.5 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.5 2.9 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.5 2.8 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.5 8.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.4 8.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.4 2.1 GO:0043515 kinetochore binding(GO:0043515)
0.4 1.3 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.4 3.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.4 1.2 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.4 3.7 GO:0005523 tropomyosin binding(GO:0005523)
0.4 2.1 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.4 1.6 GO:1903135 cupric ion binding(GO:1903135)
0.4 7.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.4 14.3 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.4 1.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.4 6.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.4 1.9 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.4 1.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.4 2.9 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.4 2.5 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.3 2.9 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.3 5.4 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.3 3.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.3 4.4 GO:0043495 protein anchor(GO:0043495)
0.3 9.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.3 1.9 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.3 1.5 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.3 0.9 GO:0030350 iron-responsive element binding(GO:0030350)
0.3 0.9 GO:0048019 receptor antagonist activity(GO:0048019)
0.3 8.1 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.3 2.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.3 2.0 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.3 2.6 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.3 4.0 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.3 1.1 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.3 1.3 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.3 1.1 GO:0070012 oligopeptidase activity(GO:0070012)
0.3 1.6 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.3 8.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.3 0.8 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.3 14.6 GO:0036002 pre-mRNA binding(GO:0036002)
0.3 1.0 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.3 1.0 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.2 0.7 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.2 2.0 GO:0048495 Roundabout binding(GO:0048495)
0.2 0.7 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.2 5.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 1.7 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.2 0.7 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.2 1.0 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.2 1.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 0.9 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.2 0.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.2 0.9 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.2 4.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.2 2.7 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.2 0.9 GO:0042834 peptidoglycan binding(GO:0042834)
0.2 0.6 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.2 0.8 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.2 6.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 0.8 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.2 3.6 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.2 1.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.2 0.6 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.2 1.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.2 0.5 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.2 1.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.2 1.0 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.2 0.8 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.2 1.8 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.2 0.8 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.2 1.5 GO:0070324 thyroid hormone binding(GO:0070324)
0.2 1.9 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.2 6.7 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.2 1.5 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.1 0.4 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 1.2 GO:0019956 chemokine binding(GO:0019956)
0.1 0.4 GO:0004966 galanin receptor activity(GO:0004966)
0.1 2.2 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 0.6 GO:0070573 tripeptidyl-peptidase activity(GO:0008240) metallodipeptidase activity(GO:0070573)
0.1 1.6 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.1 0.4 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 1.0 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 1.7 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 0.4 GO:0098809 nitrite reductase activity(GO:0098809)
0.1 1.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.7 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 19.5 GO:0030674 protein binding, bridging(GO:0030674)
0.1 1.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.8 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 0.4 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.1 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 4.0 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.6 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 1.3 GO:0035198 miRNA binding(GO:0035198)
0.1 0.9 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.1 3.5 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 0.4 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.1 0.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 1.0 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.2 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.1 0.5 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.1 0.5 GO:0001847 opsonin receptor activity(GO:0001847)
0.1 3.6 GO:0030507 spectrin binding(GO:0030507)
0.1 1.0 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 4.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 0.3 GO:0003692 left-handed Z-DNA binding(GO:0003692)
0.1 1.8 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 2.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.6 GO:0043532 angiostatin binding(GO:0043532)
0.1 0.5 GO:0070330 aromatase activity(GO:0070330)
0.1 2.2 GO:0043236 laminin binding(GO:0043236)
0.1 2.2 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 0.2 GO:0031687 A2A adenosine receptor binding(GO:0031687)
0.1 2.1 GO:0043422 protein kinase B binding(GO:0043422)
0.1 0.7 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.1 0.6 GO:0016917 GABA receptor activity(GO:0016917)
0.1 0.4 GO:0050733 RS domain binding(GO:0050733)
0.1 0.7 GO:0005261 cation channel activity(GO:0005261)
0.1 1.2 GO:0005521 lamin binding(GO:0005521)
0.1 0.3 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 1.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.9 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 1.0 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 1.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 1.9 GO:0043274 phospholipase binding(GO:0043274)
0.1 3.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 2.0 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 43.8 GO:0005509 calcium ion binding(GO:0005509)
0.1 0.3 GO:0004448 isocitrate dehydrogenase activity(GO:0004448) isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.1 0.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 1.1 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 1.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 0.6 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 0.5 GO:0031419 cobalamin binding(GO:0031419)
0.1 12.9 GO:0017124 SH3 domain binding(GO:0017124)
0.1 0.7 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.1 0.8 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 1.7 GO:0030276 clathrin binding(GO:0030276)
0.1 0.1 GO:0070052 collagen V binding(GO:0070052)
0.1 0.6 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 0.1 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.1 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.4 GO:0043426 MRF binding(GO:0043426)
0.1 7.1 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1 0.6 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.3 GO:0042979 ornithine decarboxylase regulator activity(GO:0042979)
0.1 0.4 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.1 0.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.1 0.4 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.1 1.2 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.9 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.6 GO:0003691 double-stranded telomeric DNA binding(GO:0003691) telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1 0.7 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229) phospholipid scramblase activity(GO:0017128)
0.1 0.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 0.9 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.1 0.3 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.5 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.1 0.6 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 4.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 0.4 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.1 0.3 GO:0032407 MutSalpha complex binding(GO:0032407)
0.1 0.3 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 1.3 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 2.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.6 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 0.3 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 1.2 GO:0031489 myosin V binding(GO:0031489)
0.1 0.8 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 0.2 GO:2001069 glycogen binding(GO:2001069)
0.1 0.8 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 11.9 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 2.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 3.1 GO:0002039 p53 binding(GO:0002039)
0.0 0.5 GO:0042165 neurotransmitter binding(GO:0042165)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.3 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.4 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 0.2 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 2.3 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.8 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.7 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.3 GO:0036122 BMP binding(GO:0036122)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 3.3 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 1.1 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 1.0 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.2 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872) fructose-6-phosphate binding(GO:0070095)
0.0 0.6 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 1.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.7 GO:0051117 ATPase binding(GO:0051117)
0.0 0.2 GO:0035254 glutamate receptor binding(GO:0035254)
0.0 0.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.7 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.4 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.0 13.9 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.4 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.6 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 1.7 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 1.6 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.3 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0032450 alpha-1,4-glucosidase activity(GO:0004558) maltose alpha-glucosidase activity(GO:0032450)
0.0 0.4 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 5.9 GO:0003924 GTPase activity(GO:0003924)
0.0 0.5 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.3 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.1 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.0 0.7 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.2 GO:0048018 receptor agonist activity(GO:0048018)
0.0 3.1 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.6 GO:0032947 protein complex scaffold(GO:0032947)
0.0 1.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.4 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.1 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.9 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 4.0 GO:0015631 tubulin binding(GO:0015631)
0.0 0.1 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.4 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.0 2.3 GO:0004386 helicase activity(GO:0004386)
0.0 0.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.2 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.7 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.5 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.1 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.3 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.8 PID_CONE_PATHWAY Visual signal transduction: Cones
0.3 21.7 PID_LKB1_PATHWAY LKB1 signaling events
0.2 1.6 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.2 11.5 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.2 2.4 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.2 9.0 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.2 3.0 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.2 3.3 PID_IGF1_PATHWAY IGF1 pathway
0.2 9.2 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 6.6 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.1 9.1 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.1 3.7 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.1 6.3 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 3.2 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.1 3.6 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 6.3 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.1 4.6 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 3.9 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 2.7 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.1 0.7 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.1 1.2 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 1.0 PID_PI3KCI_PATHWAY Class I PI3K signaling events
0.1 4.0 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 2.7 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.1 3.7 PID_INSULIN_PATHWAY Insulin Pathway
0.1 0.5 PID_VEGFR1_PATHWAY VEGFR1 specific signals
0.1 1.9 PID_HIV_NEF_PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1 3.1 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 1.9 PID_ERBB4_PATHWAY ErbB4 signaling events
0.1 3.9 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.1 1.7 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.1 0.8 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.1 2.1 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.1 1.0 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.1 0.8 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.1 2.4 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.1 0.9 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.1 1.6 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 2.7 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.1 1.5 PID_IL8_CXCR2_PATHWAY IL8- and CXCR2-mediated signaling events
0.1 1.5 SIG_CHEMOTAXIS Genes related to chemotaxis
0.1 0.6 SIG_BCR_SIGNALING_PATHWAY Members of the BCR signaling pathway
0.0 0.6 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.0 1.6 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 1.2 PID_IL2_1PATHWAY IL2-mediated signaling events
0.0 1.3 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.3 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.2 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.1 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.5 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.3 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 0.4 PID_REELIN_PATHWAY Reelin signaling pathway
0.0 0.2 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.1 PID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.5 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.2 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.0 0.3 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.8 PID_ERBB1_DOWNSTREAM_PATHWAY ErbB1 downstream signaling
0.0 0.1 ST_GA13_PATHWAY G alpha 13 Pathway
0.0 0.4 PID_TCR_PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.4 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 0.4 PID_ATR_PATHWAY ATR signaling pathway
0.0 0.2 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.1 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.3 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
1.7 14.0 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.7 17.8 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.7 7.2 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.6 7.7 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.6 7.4 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.5 3.3 REACTOME_PEPTIDE_HORMONE_BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.5 9.0 REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT Genes involved in Ligand-gated ion channel transport
0.5 12.3 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.4 5.2 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.4 4.3 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.4 6.1 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.3 4.0 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.3 2.7 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.3 6.2 REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.3 9.6 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.3 5.1 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.3 10.6 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.3 8.3 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 2.2 REACTOME_PD1_SIGNALING Genes involved in PD-1 signaling
0.2 3.1 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.2 2.2 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.2 2.3 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.2 7.3 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.2 2.4 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS Genes involved in Trafficking of AMPA receptors
0.2 1.3 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2 5.0 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.2 1.2 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.2 4.9 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.2 1.5 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.2 1.8 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.1 2.8 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.1 9.1 REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS Genes involved in G alpha (z) signalling events
0.1 1.0 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 2.0 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 2.0 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 1.1 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 4.1 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.1 2.7 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.1 0.8 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.1 0.6 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 0.4 REACTOME_NOD1_2_SIGNALING_PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 2.5 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.1 0.9 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 2.1 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.8 REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 1.5 REACTOME_PHOSPHORYLATION_OF_THE_APC_C Genes involved in Phosphorylation of the APC/C
0.1 8.5 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 1.8 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.1 0.9 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 5.9 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.1 0.4 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 1.7 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 1.5 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 0.8 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 0.4 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 0.7 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.1 1.9 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.1 1.3 REACTOME_MICRORNA_MIRNA_BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 1.7 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.1 1.0 REACTOME_ELONGATION_ARREST_AND_RECOVERY Genes involved in Elongation arrest and recovery
0.1 1.2 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.1 0.7 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 0.7 REACTOME_ER_PHAGOSOME_PATHWAY Genes involved in ER-Phagosome pathway
0.1 1.6 REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE Genes involved in GPVI-mediated activation cascade
0.1 2.2 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.1 0.7 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 0.5 REACTOME_AMYLOIDS Genes involved in Amyloids
0.0 0.3 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.2 REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.5 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.8 REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.7 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 4.4 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.4 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.8 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.2 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.3 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 1.2 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.0 0.7 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.0 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.1 REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.7 REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.2 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.3 REACTOME_REGULATION_OF_WATER_BALANCE_BY_RENAL_AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.5 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.3 REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH Genes involved in NCAM signaling for neurite out-growth
0.0 0.3 REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.7 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.7 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.3 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 2.4 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.7 REACTOME_G_ALPHA_S_SIGNALLING_EVENTS Genes involved in G alpha (s) signalling events
0.0 0.3 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.2 REACTOME_PERK_REGULATED_GENE_EXPRESSION Genes involved in PERK regulated gene expression
0.0 0.1 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.6 REACTOME_NEURONAL_SYSTEM Genes involved in Neuronal System
0.0 0.7 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.0 1.1 REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS Genes involved in G alpha (q) signalling events
0.0 0.3 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism