Motif ID: Osr2_Osr1

Z-value: 0.772

Transcription factors associated with Osr2_Osr1:

Gene SymbolEntrez IDGene Name
Osr1 ENSMUSG00000048387.7 Osr1
Osr2 ENSMUSG00000022330.4 Osr2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Osr1mm10_v2_chr12_+_9574437_9574448-0.009.9e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Osr2_Osr1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_90203980 4.237 ENSMUST00000065587.4
ENSMUST00000159654.1
Ackr3

atypical chemokine receptor 3

chr2_-_80128834 3.555 ENSMUST00000102654.4
ENSMUST00000102655.3
Pde1a

phosphodiesterase 1A, calmodulin-dependent

chr4_+_13743424 3.039 ENSMUST00000006761.3
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr4_-_134254076 2.226 ENSMUST00000060050.5
Grrp1
glycine/arginine rich protein 1
chr2_+_136892168 1.826 ENSMUST00000099311.2
Slx4ip
SLX4 interacting protein
chr4_+_135963742 1.803 ENSMUST00000149636.1
ENSMUST00000143304.1
Gale

galactose-4-epimerase, UDP

chr19_+_48206025 1.603 ENSMUST00000078880.5
Sorcs3
sortilin-related VPS10 domain containing receptor 3
chr19_+_20601958 1.548 ENSMUST00000087638.3
Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
chr15_+_84232030 1.465 ENSMUST00000023072.6
Parvb
parvin, beta
chr3_-_89322883 1.427 ENSMUST00000029673.5
Efna3
ephrin A3
chr5_+_107497762 1.411 ENSMUST00000152474.1
ENSMUST00000060553.7
A830010M20Rik

RIKEN cDNA A830010M20 gene

chr5_+_107497718 1.309 ENSMUST00000112671.2
A830010M20Rik
RIKEN cDNA A830010M20 gene
chr6_-_59024470 1.294 ENSMUST00000089860.5
Fam13a
family with sequence similarity 13, member A
chr19_-_16873830 1.284 ENSMUST00000072915.2
Foxb2
forkhead box B2
chr9_-_16378231 1.283 ENSMUST00000082170.5
Fat3
FAT tumor suppressor homolog 3 (Drosophila)
chr15_-_20666750 1.280 ENSMUST00000052910.4
Acot10
acyl-CoA thioesterase 10
chr19_+_54045182 1.268 ENSMUST00000036700.5
Adra2a
adrenergic receptor, alpha 2a
chr7_-_57509995 1.251 ENSMUST00000068456.6
Gabra5
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5
chr10_-_109823585 1.246 ENSMUST00000161582.1
Nav3
neuron navigator 3
chr3_-_127225847 1.075 ENSMUST00000182726.1
ENSMUST00000182779.1
Ank2

ankyrin 2, brain

chr6_-_144209448 1.062 ENSMUST00000077160.5
Sox5
SRY-box containing gene 5
chr18_-_31317043 1.057 ENSMUST00000139924.1
ENSMUST00000153060.1
Rit2

Ras-like without CAAX 2

chr7_+_126950687 1.051 ENSMUST00000106333.1
Sez6l2
seizure related 6 homolog like 2
chr6_-_59024340 1.017 ENSMUST00000173193.1
Fam13a
family with sequence similarity 13, member A
chr7_+_97842917 0.999 ENSMUST00000033040.5
Pak1
p21 protein (Cdc42/Rac)-activated kinase 1
chr4_+_135963720 0.993 ENSMUST00000102541.3
Gale
galactose-4-epimerase, UDP
chr13_-_40733768 0.991 ENSMUST00000110193.2
Tfap2a
transcription factor AP-2, alpha
chr6_-_144209471 0.979 ENSMUST00000038815.7
Sox5
SRY-box containing gene 5
chr4_+_43383449 0.978 ENSMUST00000135216.1
ENSMUST00000152322.1
Rusc2

RUN and SH3 domain containing 2

chr11_-_100759942 0.965 ENSMUST00000107363.2
Kcnh4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr11_-_100759740 0.933 ENSMUST00000107361.2
Kcnh4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr8_+_12984246 0.927 ENSMUST00000110873.3
ENSMUST00000173006.1
ENSMUST00000145067.1
Mcf2l


mcf.2 transforming sequence-like


chr7_-_123500449 0.920 ENSMUST00000042470.7
ENSMUST00000128217.1
Zkscan2

zinc finger with KRAB and SCAN domains 2

chr6_-_144209558 0.896 ENSMUST00000111749.1
ENSMUST00000170367.2
Sox5

SRY-box containing gene 5

chr13_+_4191163 0.885 ENSMUST00000021634.2
Akr1c13
aldo-keto reductase family 1, member C13
chr10_+_77829467 0.857 ENSMUST00000092368.2
Tspear
thrombospondin type laminin G domain and EAR repeats
chr3_-_127225917 0.829 ENSMUST00000182064.1
ENSMUST00000182662.1
Ank2

ankyrin 2, brain

chr9_-_50739365 0.770 ENSMUST00000117093.1
ENSMUST00000121634.1
Dixdc1

DIX domain containing 1

chr12_-_108702265 0.763 ENSMUST00000167978.1
ENSMUST00000021691.4
Degs2

degenerative spermatocyte homolog 2 (Drosophila), lipid desaturase

chr7_+_97720839 0.700 ENSMUST00000070021.1
Gm9990
predicted gene 9990
chr10_+_74967164 0.700 ENSMUST00000037813.4
Gnaz
guanine nucleotide binding protein, alpha z subunit
chr4_+_102087543 0.698 ENSMUST00000106911.1
Pde4b
phosphodiesterase 4B, cAMP specific
chr4_-_119383732 0.681 ENSMUST00000044781.2
ENSMUST00000084307.3
Ccdc30

coiled-coil domain containing 30

chr10_+_77864623 0.638 ENSMUST00000092366.2
Tspear
thrombospondin type laminin G domain and EAR repeats
chr2_+_83644435 0.631 ENSMUST00000081591.6
Zc3h15
zinc finger CCCH-type containing 15
chr6_+_37900477 0.623 ENSMUST00000120238.1
Trim24
tripartite motif-containing 24
chr14_-_123627059 0.605 ENSMUST00000000201.5
Nalcn
sodium leak channel, non-selective
chr2_+_153741274 0.600 ENSMUST00000028981.8
Mapre1
microtubule-associated protein, RP/EB family, member 1
chr16_+_91729281 0.597 ENSMUST00000114001.1
ENSMUST00000113999.1
ENSMUST00000064797.5
ENSMUST00000114002.2
ENSMUST00000095909.3
ENSMUST00000056482.7
ENSMUST00000113996.1
Itsn1






intersectin 1 (SH3 domain protein 1A)






chr9_+_87022014 0.594 ENSMUST00000168529.2
ENSMUST00000174724.1
ENSMUST00000173126.1
Cyb5r4


cytochrome b5 reductase 4


chr15_-_43869993 0.591 ENSMUST00000067469.4
Tmem74
transmembrane protein 74
chr8_-_22653406 0.565 ENSMUST00000033938.5
Polb
polymerase (DNA directed), beta
chr16_+_91729436 0.556 ENSMUST00000113993.1
Itsn1
intersectin 1 (SH3 domain protein 1A)
chr18_+_38296805 0.556 ENSMUST00000171461.1
Rnf14
ring finger protein 14
chr12_+_70974621 0.553 ENSMUST00000160027.1
ENSMUST00000160864.1
Psma3

proteasome (prosome, macropain) subunit, alpha type 3

chr7_-_119720742 0.544 ENSMUST00000033236.7
Thumpd1
THUMP domain containing 1
chr6_+_11925869 0.542 ENSMUST00000115510.1
ENSMUST00000115511.2
ENSMUST00000090632.4
Phf14


PHD finger protein 14


chr10_-_57532489 0.536 ENSMUST00000020027.4
Serinc1
serine incorporator 1
chr5_-_112589990 0.535 ENSMUST00000183186.1
ENSMUST00000182949.1
1700034G24Rik

RIKEN cDNA 1700034G24 gene

chr10_-_57532416 0.525 ENSMUST00000169122.1
Serinc1
serine incorporator 1
chr6_+_57702601 0.516 ENSMUST00000072954.1
ENSMUST00000050077.8
Lancl2

LanC (bacterial lantibiotic synthetase component C)-like 2

chr13_+_74406387 0.510 ENSMUST00000090860.6
Gm10116
predicted pseudogene 10116
chr2_+_35622160 0.492 ENSMUST00000112992.2
Dab2ip
disabled 2 interacting protein
chr19_-_14598031 0.476 ENSMUST00000167776.2
Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr15_-_27681498 0.468 ENSMUST00000100739.3
Fam105a
family with sequence similarity 105, member A
chr19_-_14597983 0.458 ENSMUST00000052011.7
Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr6_-_89595647 0.455 ENSMUST00000032172.8
ENSMUST00000113550.3
Chchd6

coiled-coil-helix-coiled-coil-helix domain containing 6

chr9_-_86546795 0.448 ENSMUST00000167814.1
Gm17530
predicted gene, 17530
chr14_+_120275669 0.440 ENSMUST00000088419.6
ENSMUST00000167459.1
Mbnl2

muscleblind-like 2

chr7_+_96951505 0.436 ENSMUST00000044466.5
Nars2
asparaginyl-tRNA synthetase 2 (mitochondrial)(putative)
chr7_-_30743681 0.432 ENSMUST00000182634.1
Gapdhs
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr7_-_127890918 0.427 ENSMUST00000121394.1
Prss53
protease, serine, 53
chr11_+_69991633 0.422 ENSMUST00000108592.1
Gabarap
gamma-aminobutyric acid receptor associated protein
chr2_+_176831140 0.416 ENSMUST00000122218.2
ENSMUST00000126726.1
Gm14408

predicted gene 14408

chr15_-_78718113 0.410 ENSMUST00000088592.4
Elfn2
leucine rich repeat and fibronectin type III, extracellular 2
chr11_+_72301613 0.404 ENSMUST00000151440.1
ENSMUST00000146233.1
ENSMUST00000140842.2
Xaf1


XIAP associated factor 1


chr9_-_53610329 0.403 ENSMUST00000034547.5
Acat1
acetyl-Coenzyme A acetyltransferase 1
chr19_-_6067785 0.400 ENSMUST00000162575.1
ENSMUST00000159084.1
ENSMUST00000161718.1
ENSMUST00000162810.1
ENSMUST00000025713.5
ENSMUST00000113543.2
ENSMUST00000161528.1
Tm7sf2






transmembrane 7 superfamily member 2






chrX_-_111463043 0.395 ENSMUST00000065976.5
Rps6ka6
ribosomal protein S6 kinase polypeptide 6
chr1_+_171270321 0.388 ENSMUST00000064272.3
ENSMUST00000141999.1
ENSMUST00000111313.3
B4galt3


UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 3


chr1_+_44119952 0.383 ENSMUST00000114709.2
Bivm
basic, immunoglobulin-like variable motif containing
chr11_+_75588064 0.379 ENSMUST00000143219.1
ENSMUST00000179521.1
ENSMUST00000179445.1
Pitpna


phosphatidylinositol transfer protein, alpha


chr8_+_3621529 0.376 ENSMUST00000156380.2
Pet100
PET100 homolog (S. cerevisiae)
chr4_-_138913915 0.376 ENSMUST00000097830.3
Otud3
OTU domain containing 3
chr1_+_179546303 0.373 ENSMUST00000040706.8
Cnst
consortin, connexin sorting protein
chr6_-_86733268 0.371 ENSMUST00000001185.7
Gmcl1
germ cell-less homolog 1 (Drosophila)
chr2_+_35622010 0.365 ENSMUST00000091010.5
Dab2ip
disabled 2 interacting protein
chr4_+_139622842 0.344 ENSMUST00000039818.9
Aldh4a1
aldehyde dehydrogenase 4 family, member A1
chr14_+_55604550 0.339 ENSMUST00000138037.1
Irf9
interferon regulatory factor 9
chr6_-_86733218 0.339 ENSMUST00000113679.1
Gmcl1
germ cell-less homolog 1 (Drosophila)
chr10_+_127501672 0.337 ENSMUST00000160019.1
ENSMUST00000160610.1
Stac3

SH3 and cysteine rich domain 3

chr10_+_127501707 0.326 ENSMUST00000035839.2
Stac3
SH3 and cysteine rich domain 3
chr11_-_70239794 0.324 ENSMUST00000040428.3
Rnasek
ribonuclease, RNase K
chr16_-_32868325 0.321 ENSMUST00000089684.3
ENSMUST00000040986.8
ENSMUST00000115105.2
1700021K19Rik


RIKEN cDNA 1700021K19 gene


chr7_+_96951552 0.318 ENSMUST00000107159.1
Nars2
asparaginyl-tRNA synthetase 2 (mitochondrial)(putative)
chr6_+_57703051 0.317 ENSMUST00000151042.1
Lancl2
LanC (bacterial lantibiotic synthetase component C)-like 2
chr8_+_25720054 0.309 ENSMUST00000068916.8
ENSMUST00000139836.1
Ppapdc1b

phosphatidic acid phosphatase type 2 domain containing 1B

chr2_-_156180135 0.307 ENSMUST00000126992.1
ENSMUST00000146288.1
ENSMUST00000029149.6
ENSMUST00000109587.2
ENSMUST00000109584.1
Rbm39




RNA binding motif protein 39




chr7_+_44849216 0.301 ENSMUST00000054343.8
Akt1s1
AKT1 substrate 1 (proline-rich)
chrX_-_7319291 0.300 ENSMUST00000128319.1
Clcn5
chloride channel 5
chr14_-_70599832 0.299 ENSMUST00000022690.9
Fam160b2
family with sequence similarity 160, member B2
chr9_-_35267746 0.299 ENSMUST00000125087.1
ENSMUST00000121564.1
ENSMUST00000063782.5
ENSMUST00000059057.7
Fam118b



family with sequence similarity 118, member B



chr12_-_110682606 0.298 ENSMUST00000070659.5
1700001K19Rik
RIKEN cDNA 1700001K19 gene
chr14_-_20480106 0.293 ENSMUST00000065504.9
ENSMUST00000100844.4
Anxa7

annexin A7

chr2_+_122028544 0.290 ENSMUST00000028668.7
Eif3j1
eukaryotic translation initiation factor 3, subunit J1
chr9_+_7184514 0.286 ENSMUST00000034499.8
Dcun1d5
DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae)
chr12_+_84114321 0.285 ENSMUST00000123491.1
ENSMUST00000046340.2
ENSMUST00000136159.1
Dnal1


dynein, axonemal, light chain 1


chr2_-_126618655 0.284 ENSMUST00000028838.4
Hdc
histidine decarboxylase
chr6_+_51523901 0.274 ENSMUST00000049152.8
Snx10
sorting nexin 10
chr3_-_116614587 0.271 ENSMUST00000041524.4
Trmt13
tRNA methyltransferase 13
chr7_+_141949688 0.258 ENSMUST00000018971.8
ENSMUST00000078200.5
Brsk2

BR serine/threonine kinase 2

chr10_+_43901782 0.255 ENSMUST00000054418.5
Rtn4ip1
reticulon 4 interacting protein 1
chr9_-_48495321 0.255 ENSMUST00000170000.2
Rbm7
RNA binding motif protein 7
chr19_+_17394037 0.249 ENSMUST00000025617.3
Rfk
riboflavin kinase
chr19_-_6942406 0.247 ENSMUST00000099782.3
Gpr137
G protein-coupled receptor 137
chr4_+_134496996 0.245 ENSMUST00000095074.3
Paqr7
progestin and adipoQ receptor family member VII
chr5_+_76529303 0.243 ENSMUST00000087133.4
ENSMUST00000113493.1
ENSMUST00000049469.6
Exoc1


exocyst complex component 1


chr16_+_17070281 0.238 ENSMUST00000090199.3
Ypel1
yippee-like 1 (Drosophila)
chr9_-_45906837 0.234 ENSMUST00000161203.1
ENSMUST00000058720.5
ENSMUST00000160699.1
Rnf214


ring finger protein 214


chr19_-_41206774 0.226 ENSMUST00000025986.7
ENSMUST00000169941.1
Tll2

tolloid-like 2

chr4_+_134496966 0.222 ENSMUST00000134506.1
ENSMUST00000136171.1
ENSMUST00000125330.1
Paqr7


progestin and adipoQ receptor family member VII


chr8_+_45975514 0.221 ENSMUST00000034051.6
Ufsp2
UFM1-specific peptidase 2
chr9_-_50344981 0.219 ENSMUST00000076364.4
Rpl10-ps3
ribosomal protein L10, pseudogene 3
chr15_+_35371498 0.204 ENSMUST00000048646.7
Vps13b
vacuolar protein sorting 13B (yeast)
chr13_-_78196373 0.193 ENSMUST00000125176.2
Nr2f1
nuclear receptor subfamily 2, group F, member 1
chr9_-_63377835 0.192 ENSMUST00000034920.9
Map2k5
mitogen-activated protein kinase kinase 5
chr7_+_141949846 0.192 ENSMUST00000172652.1
Brsk2
BR serine/threonine kinase 2
chr1_-_10038106 0.192 ENSMUST00000027050.3
Cops5
COP9 (constitutive photomorphogenic) homolog, subunit 5 (Arabidopsis thaliana)
chr9_-_55283582 0.182 ENSMUST00000114306.1
ENSMUST00000164721.1
Nrg4

neuregulin 4

chr10_+_82058417 0.179 ENSMUST00000105313.1
Zfp873
zinc finger protein 873
chr6_+_90369486 0.179 ENSMUST00000113539.1
ENSMUST00000075117.3
ENSMUST00000045740.6
Zxdc


ZXD family zinc finger C


chr19_+_18631927 0.176 ENSMUST00000159572.1
ENSMUST00000042392.7
Nmrk1

nicotinamide riboside kinase 1

chr19_-_18631754 0.176 ENSMUST00000025631.6
Ostf1
osteoclast stimulating factor 1
chr2_+_131950855 0.168 ENSMUST00000110170.1
ENSMUST00000110172.2
ENSMUST00000110171.2
Prnd


prion protein dublet


chr5_+_19227046 0.165 ENSMUST00000088516.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr9_-_104262900 0.152 ENSMUST00000035170.6
Dnajc13
DnaJ (Hsp40) homolog, subfamily C, member 13
chr1_+_74601548 0.148 ENSMUST00000087186.4
Stk36
serine/threonine kinase 36
chr16_-_91728599 0.146 ENSMUST00000122254.1
Cryzl1
crystallin, zeta (quinone reductase)-like 1
chr19_+_27217011 0.140 ENSMUST00000164746.1
ENSMUST00000172302.1
Vldlr

very low density lipoprotein receptor

chr5_+_105876532 0.138 ENSMUST00000150440.1
ENSMUST00000031227.4
Zfp326

zinc finger protein 326

chr16_-_91728701 0.134 ENSMUST00000114023.2
ENSMUST00000117644.1
Cryzl1

crystallin, zeta (quinone reductase)-like 1

chr2_-_28840274 0.127 ENSMUST00000037117.5
ENSMUST00000171404.1
Gtf3c4

general transcription factor IIIC, polypeptide 4

chr10_-_63927434 0.126 ENSMUST00000079279.3
Gm10118
predicted gene 10118
chr11_-_102556122 0.126 ENSMUST00000143842.1
Gpatch8
G patch domain containing 8
chr5_-_113650390 0.124 ENSMUST00000047936.6
Cmklr1
chemokine-like receptor 1
chr11_+_80209019 0.121 ENSMUST00000077451.7
ENSMUST00000055056.9
Rhot1

ras homolog gene family, member T1

chr1_-_181183739 0.118 ENSMUST00000159290.1
Wdr26
WD repeat domain 26
chr4_-_116555896 0.111 ENSMUST00000069674.5
ENSMUST00000106478.2
Tmem69

transmembrane protein 69

chr6_+_87887814 0.110 ENSMUST00000113607.3
ENSMUST00000049966.5
Copg1

coatomer protein complex, subunit gamma 1

chr16_-_18413452 0.106 ENSMUST00000165430.1
ENSMUST00000147720.1
Comt

catechol-O-methyltransferase

chr9_-_96719404 0.106 ENSMUST00000140121.1
Zbtb38
zinc finger and BTB domain containing 38
chr9_+_48495345 0.103 ENSMUST00000048824.7
Gm5617
predicted gene 5617
chr18_-_24020307 0.099 ENSMUST00000153337.1
ENSMUST00000148525.1
Zfp191

zinc finger protein 191

chr9_+_45906513 0.095 ENSMUST00000039059.6
Pcsk7
proprotein convertase subtilisin/kexin type 7
chrY_+_90784738 0.094 ENSMUST00000179483.1
Erdr1
erythroid differentiation regulator 1
chr17_-_32822200 0.089 ENSMUST00000179695.1
Zfp799
zinc finger protein 799
chr7_+_141949982 0.085 ENSMUST00000105989.2
ENSMUST00000075528.5
ENSMUST00000174499.1
Brsk2


BR serine/threonine kinase 2


chr8_+_31150307 0.073 ENSMUST00000098842.2
Tti2
TELO2 interacting protein 2
chr7_-_127875633 0.065 ENSMUST00000106261.1
ENSMUST00000144721.1
Zfp668

zinc finger protein 668

chr18_-_70141568 0.059 ENSMUST00000121693.1
Rab27b
RAB27b, member RAS oncogene family
chrX_-_7947553 0.053 ENSMUST00000133349.1
Hdac6
histone deacetylase 6
chr1_-_179546261 0.052 ENSMUST00000027769.5
Tfb2m
transcription factor B2, mitochondrial
chr16_-_91728975 0.051 ENSMUST00000073466.6
Cryzl1
crystallin, zeta (quinone reductase)-like 1
chr4_+_130913120 0.043 ENSMUST00000151698.1
Laptm5
lysosomal-associated protein transmembrane 5
chr2_-_67194695 0.037 ENSMUST00000147939.1
Gm13598
predicted gene 13598
chr9_-_96719549 0.027 ENSMUST00000128269.1
Zbtb38
zinc finger and BTB domain containing 38
chr12_+_85110833 0.025 ENSMUST00000053811.8
Dlst
dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
chr9_-_108578657 0.024 ENSMUST00000068700.5
Wdr6
WD repeat domain 6
chr11_-_98149551 0.021 ENSMUST00000103143.3
Fbxl20
F-box and leucine-rich repeat protein 20
chr2_+_144368961 0.021 ENSMUST00000028911.8
ENSMUST00000147747.1
ENSMUST00000183618.1
Csrp2bp

Pet117
cysteine and glycine-rich protein 2 binding protein

PET117 homolog (S. cerevisiae)
chr16_+_4886100 0.013 ENSMUST00000070658.8
ENSMUST00000023159.8
Mgrn1

mahogunin, ring finger 1

chr15_-_89429851 0.010 ENSMUST00000023289.6
Chkb
choline kinase beta
chr9_+_3532295 0.007 ENSMUST00000115733.1
Gucy1a2
guanylate cyclase 1, soluble, alpha 2
chr2_+_180071793 0.007 ENSMUST00000108901.1
Mtg2
mitochondrial ribosome associated GTPase 2
chr3_+_145576196 0.004 ENSMUST00000098534.4
Znhit6
zinc finger, HIT type 6
chr19_+_4962306 0.002 ENSMUST00000025836.4
Mrpl11
mitochondrial ribosomal protein L11
chrY_-_6681243 0.000 ENSMUST00000115940.1
Gm21719
predicted gene, 21719

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.8 GO:0061623 glycolytic process from galactose(GO:0061623)
0.5 1.0 GO:0021557 oculomotor nerve development(GO:0021557)
0.5 1.5 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.4 1.5 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.4 2.9 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.3 1.0 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.3 1.3 GO:0035624 receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) thermoception(GO:0050955)
0.3 1.4 GO:1905247 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.3 0.8 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.3 0.8 GO:0006667 sphinganine metabolic process(GO:0006667)
0.2 1.9 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.2 1.1 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.2 3.6 GO:0046069 cGMP catabolic process(GO:0046069)
0.2 0.8 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.2 0.6 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.2 0.5 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.2 0.9 GO:0036324 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144) vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.2 1.1 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.2 0.6 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 0.4 GO:0006550 isoleucine catabolic process(GO:0006550) acetyl-CoA catabolic process(GO:0046356) ketone body catabolic process(GO:0046952)
0.1 0.4 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.1 0.6 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 0.4 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.1 4.2 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 0.6 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.1 0.2 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.1 0.3 GO:0030576 Cajal body organization(GO:0030576)
0.1 0.3 GO:0001692 histamine metabolic process(GO:0001692) histidine metabolic process(GO:0006547) imidazole-containing compound catabolic process(GO:0052805)
0.1 0.2 GO:0070375 ERK5 cascade(GO:0070375)
0.1 0.8 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 1.6 GO:1900452 regulation of long term synaptic depression(GO:1900452)
0.1 0.7 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.1 GO:0031335 regulation of sulfur amino acid metabolic process(GO:0031335)
0.0 0.1 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.0 0.2 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 1.3 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.4 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 1.1 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 1.3 GO:0010842 retina layer formation(GO:0010842)
0.0 0.3 GO:0006560 proline metabolic process(GO:0006560)
0.0 0.1 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.0 0.4 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.7 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 2.0 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.4 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.5 GO:0042407 cristae formation(GO:0042407)
0.0 0.3 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.0 0.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.7 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.4 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.2 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.0 0.2 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.0 0.9 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.4 GO:0030813 positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.0 0.1 GO:0070844 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0 0.2 GO:1903894 regulation of IRE1-mediated unfolded protein response(GO:1903894)
0.0 0.6 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.3 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 1.2 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.6 GO:0042168 heme metabolic process(GO:0042168)
0.0 1.1 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.3 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:1902513 regulation of organelle transport along microtubule(GO:1902513)
0.0 0.2 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.2 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.1 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.8 GO:0006400 tRNA modification(GO:0006400)
0.0 0.2 GO:0019363 pyridine nucleotide biosynthetic process(GO:0019363)
0.0 0.1 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0097447 dendritic tree(GO:0097447)
0.2 0.9 GO:1990032 parallel fiber(GO:1990032)
0.2 0.6 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 0.3 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 0.6 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 1.3 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 1.0 GO:0071437 invadopodium(GO:0071437)
0.1 0.2 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 1.9 GO:0031430 M band(GO:0031430)
0.1 5.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 0.6 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 0.5 GO:0061617 MICOS complex(GO:0061617)
0.0 0.3 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 3.9 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.5 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.3 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.4 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.6 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.4 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.8 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 2.4 GO:0030027 lamellipodium(GO:0030027)
0.0 1.9 GO:0044798 nuclear transcription factor complex(GO:0044798)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494) C-X-C chemokine binding(GO:0019958)
0.5 3.6 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.4 1.3 GO:0004936 alpha-adrenergic receptor activity(GO:0004936) epinephrine binding(GO:0051379)
0.3 1.5 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.3 0.8 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.3 0.8 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
0.2 2.8 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 0.9 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.7 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 1.7 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.4 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.4 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.1 1.1 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 1.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.4 GO:0016453 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.1 0.6 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 0.8 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 1.3 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.1 0.9 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.1 1.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0034437 very-low-density lipoprotein particle binding(GO:0034189) glycoprotein transporter activity(GO:0034437)
0.0 0.6 GO:0022842 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.0 0.4 GO:0071253 connexin binding(GO:0071253)
0.0 0.1 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 1.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.4 GO:0008525 phosphatidylcholine transporter activity(GO:0008525) phosphatidylinositol transporter activity(GO:0008526)
0.0 0.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 1.9 GO:0030507 spectrin binding(GO:0030507)
0.0 0.7 GO:0070064 proline-rich region binding(GO:0070064)
0.0 1.0 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 1.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.6 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.3 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 3.6 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.4 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.6 GO:0050681 androgen receptor binding(GO:0050681)
0.0 1.1 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 1.0 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.1 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.2 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.0 1.4 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 2.1 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 0.3 ST_TYPE_I_INTERFERON_PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.2 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.5 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 0.9 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.9 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.6 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 0.2 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 1.0 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 0.6 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.4 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 1.5 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.2 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.1 3.6 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.1 1.3 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 1.3 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.1 1.0 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 1.5 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.4 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 1.1 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.1 0.6 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 1.8 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 2.4 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.6 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 2.8 REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.4 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.7 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.0 0.7 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.4 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.8 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.7 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.6 REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.4 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 0.2 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing