Motif ID: Dlx5_Dlx4
Z-value: 1.204


Transcription factors associated with Dlx5_Dlx4:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Dlx4 | ENSMUSG00000020871.7 | Dlx4 |
Dlx5 | ENSMUSG00000029755.9 | Dlx5 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Dlx5 | mm10_v2_chr6_-_6882068_6882092 | -0.56 | 1.4e-04 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.7 | 13.5 | GO:0035726 | common myeloid progenitor cell proliferation(GO:0035726) |
0.9 | 2.8 | GO:0002669 | positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) |
0.7 | 2.9 | GO:0010808 | positive regulation of synaptic vesicle priming(GO:0010808) |
0.6 | 1.7 | GO:0060023 | soft palate development(GO:0060023) |
0.5 | 1.4 | GO:0019085 | early viral transcription(GO:0019085) |
0.5 | 1.8 | GO:0060316 | positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) |
0.4 | 1.3 | GO:0060489 | orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) |
0.4 | 1.2 | GO:0003221 | right ventricular cardiac muscle tissue morphogenesis(GO:0003221) |
0.3 | 1.0 | GO:0061300 | cerebellum vasculature development(GO:0061300) |
0.3 | 1.0 | GO:0032474 | otolith morphogenesis(GO:0032474) |
0.3 | 1.0 | GO:0006592 | ornithine biosynthetic process(GO:0006592) |
0.3 | 2.6 | GO:0016576 | histone dephosphorylation(GO:0016576) |
0.3 | 1.0 | GO:0090310 | negative regulation of methylation-dependent chromatin silencing(GO:0090310) |
0.3 | 1.0 | GO:0060598 | dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598) |
0.3 | 0.9 | GO:0048840 | otolith development(GO:0048840) |
0.3 | 0.9 | GO:0071963 | establishment or maintenance of cell polarity regulating cell shape(GO:0071963) |
0.3 | 1.2 | GO:0071596 | ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596) |
0.3 | 0.9 | GO:0021577 | hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) |
0.3 | 0.9 | GO:0070649 | meiotic chromosome movement towards spindle pole(GO:0016344) formin-nucleated actin cable assembly(GO:0070649) |
0.3 | 1.4 | GO:0048245 | eosinophil chemotaxis(GO:0048245) |
0.3 | 2.0 | GO:0097151 | positive regulation of inhibitory postsynaptic potential(GO:0097151) |
0.3 | 3.9 | GO:0072431 | signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) |
0.3 | 3.3 | GO:2001269 | positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269) |
0.3 | 1.1 | GO:0070212 | protein poly-ADP-ribosylation(GO:0070212) |
0.3 | 1.1 | GO:0036091 | positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091) |
0.3 | 0.8 | GO:0038165 | oncostatin-M-mediated signaling pathway(GO:0038165) |
0.3 | 1.3 | GO:2001168 | regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168) |
0.2 | 0.5 | GO:0010920 | negative regulation of inositol phosphate biosynthetic process(GO:0010920) |
0.2 | 1.0 | GO:0090365 | regulation of mRNA modification(GO:0090365) |
0.2 | 0.9 | GO:0042905 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
0.2 | 0.7 | GO:0019046 | release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382) |
0.2 | 1.1 | GO:1904659 | glucose transmembrane transport(GO:1904659) |
0.2 | 0.9 | GO:0010749 | regulation of nitric oxide mediated signal transduction(GO:0010749) |
0.2 | 0.6 | GO:0032914 | positive regulation of transforming growth factor beta1 production(GO:0032914) |
0.2 | 1.2 | GO:0070562 | regulation of vitamin D receptor signaling pathway(GO:0070562) |
0.2 | 5.9 | GO:0010842 | retina layer formation(GO:0010842) |
0.2 | 0.6 | GO:0014022 | neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) |
0.2 | 0.6 | GO:0060743 | epithelial cell maturation involved in prostate gland development(GO:0060743) |
0.2 | 0.6 | GO:0006933 | negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933) |
0.2 | 1.7 | GO:0098700 | neurotransmitter loading into synaptic vesicle(GO:0098700) |
0.2 | 2.0 | GO:0048934 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
0.2 | 0.5 | GO:1900039 | positive regulation of cellular response to hypoxia(GO:1900039) |
0.2 | 2.6 | GO:2000042 | negative regulation of double-strand break repair via homologous recombination(GO:2000042) |
0.2 | 0.7 | GO:0060729 | intestinal epithelial structure maintenance(GO:0060729) |
0.2 | 0.7 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
0.2 | 0.3 | GO:1903860 | negative regulation of dendrite extension(GO:1903860) |
0.2 | 0.3 | GO:1902174 | positive regulation of keratinocyte apoptotic process(GO:1902174) |
0.2 | 1.3 | GO:1902746 | regulation of lens fiber cell differentiation(GO:1902746) |
0.2 | 0.5 | GO:0018103 | protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406) |
0.2 | 1.3 | GO:2000491 | positive regulation of hepatic stellate cell activation(GO:2000491) |
0.2 | 1.3 | GO:0071802 | negative regulation of podosome assembly(GO:0071802) |
0.2 | 2.7 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
0.2 | 1.4 | GO:0030035 | microspike assembly(GO:0030035) |
0.2 | 1.1 | GO:0016185 | synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) |
0.2 | 0.6 | GO:0046368 | GDP-L-fucose metabolic process(GO:0046368) |
0.1 | 1.5 | GO:0006620 | posttranslational protein targeting to membrane(GO:0006620) |
0.1 | 1.0 | GO:0000414 | regulation of histone H3-K36 methylation(GO:0000414) |
0.1 | 1.4 | GO:0098885 | modification of postsynaptic actin cytoskeleton(GO:0098885) |
0.1 | 0.8 | GO:2001012 | mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012) |
0.1 | 0.7 | GO:0033762 | response to glucagon(GO:0033762) |
0.1 | 0.5 | GO:1900377 | negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377) |
0.1 | 6.0 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
0.1 | 0.4 | GO:0002035 | brain renin-angiotensin system(GO:0002035) |
0.1 | 0.6 | GO:1902951 | negative regulation of dendritic spine maintenance(GO:1902951) |
0.1 | 0.4 | GO:0098501 | polynucleotide dephosphorylation(GO:0098501) |
0.1 | 0.4 | GO:0097278 | transforming growth factor beta activation(GO:0036363) complement-dependent cytotoxicity(GO:0097278) |
0.1 | 0.6 | GO:0015692 | vanadium ion transport(GO:0015676) lead ion transport(GO:0015692) |
0.1 | 0.5 | GO:0035609 | C-terminal protein deglutamylation(GO:0035609) |
0.1 | 1.8 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
0.1 | 0.6 | GO:0036324 | vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) |
0.1 | 0.8 | GO:0006307 | DNA dealkylation involved in DNA repair(GO:0006307) |
0.1 | 4.1 | GO:0042773 | ATP synthesis coupled electron transport(GO:0042773) |
0.1 | 0.6 | GO:0051790 | short-chain fatty acid biosynthetic process(GO:0051790) |
0.1 | 1.9 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
0.1 | 0.2 | GO:0015825 | L-serine transport(GO:0015825) |
0.1 | 0.5 | GO:0018158 | protein oxidation(GO:0018158) |
0.1 | 0.9 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
0.1 | 2.6 | GO:0051560 | mitochondrial calcium ion homeostasis(GO:0051560) |
0.1 | 0.3 | GO:0006404 | RNA import into nucleus(GO:0006404) snRNA transport(GO:0051030) |
0.1 | 0.5 | GO:2000325 | regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327) |
0.1 | 0.8 | GO:0007351 | tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595) |
0.1 | 1.4 | GO:0034390 | smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391) |
0.1 | 0.2 | GO:1900126 | negative regulation of hyaluronan biosynthetic process(GO:1900126) |
0.1 | 0.3 | GO:0016056 | rhodopsin mediated signaling pathway(GO:0016056) |
0.1 | 0.9 | GO:0051574 | positive regulation of histone H3-K9 methylation(GO:0051574) |
0.1 | 0.3 | GO:0019919 | peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919) |
0.1 | 0.3 | GO:0060912 | cardiac cell fate specification(GO:0060912) |
0.1 | 0.3 | GO:2000211 | regulation of glutamate metabolic process(GO:2000211) |
0.1 | 0.3 | GO:0071929 | alpha-tubulin acetylation(GO:0071929) |
0.1 | 3.5 | GO:0042491 | auditory receptor cell differentiation(GO:0042491) |
0.1 | 0.7 | GO:0090527 | actin filament reorganization(GO:0090527) |
0.1 | 0.2 | GO:1901856 | negative regulation of cellular respiration(GO:1901856) |
0.1 | 0.2 | GO:0015772 | disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772) |
0.1 | 0.4 | GO:0036438 | maintenance of lens transparency(GO:0036438) |
0.1 | 0.5 | GO:0090091 | positive regulation of extracellular matrix disassembly(GO:0090091) |
0.1 | 0.7 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
0.1 | 0.3 | GO:0072014 | proximal tubule development(GO:0072014) |
0.1 | 0.3 | GO:0002188 | translation reinitiation(GO:0002188) |
0.1 | 0.2 | GO:0098886 | modification of dendritic spine(GO:0098886) |
0.1 | 1.2 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
0.1 | 0.8 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
0.1 | 0.6 | GO:0090160 | Golgi to lysosome transport(GO:0090160) |
0.1 | 4.5 | GO:0008347 | glial cell migration(GO:0008347) |
0.1 | 0.4 | GO:0045919 | positive regulation of cytolysis(GO:0045919) |
0.1 | 0.6 | GO:0002523 | leukocyte migration involved in inflammatory response(GO:0002523) |
0.1 | 0.6 | GO:0035095 | behavioral response to nicotine(GO:0035095) |
0.1 | 0.6 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
0.1 | 2.1 | GO:0071385 | cellular response to glucocorticoid stimulus(GO:0071385) |
0.1 | 1.8 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.1 | 0.8 | GO:0019886 | antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886) |
0.1 | 0.3 | GO:0015744 | succinate transport(GO:0015744) |
0.1 | 0.1 | GO:0075136 | response to defenses of other organism involved in symbiotic interaction(GO:0052173) response to host defenses(GO:0052200) response to host(GO:0075136) |
0.1 | 0.3 | GO:0070859 | positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253) |
0.1 | 0.2 | GO:0002182 | cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248) |
0.1 | 1.4 | GO:0072337 | modified amino acid transport(GO:0072337) |
0.1 | 0.2 | GO:0000957 | mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960) mitochondrial RNA 3'-end processing(GO:0000965) |
0.1 | 0.5 | GO:0009301 | snRNA transcription(GO:0009301) |
0.1 | 1.6 | GO:0003009 | skeletal muscle contraction(GO:0003009) |
0.1 | 0.4 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
0.1 | 0.6 | GO:0001675 | acrosome assembly(GO:0001675) |
0.1 | 0.5 | GO:1900194 | negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194) |
0.1 | 2.6 | GO:0006493 | protein O-linked glycosylation(GO:0006493) |
0.1 | 0.2 | GO:0051387 | negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387) |
0.1 | 0.4 | GO:0060395 | SMAD protein signal transduction(GO:0060395) |
0.1 | 0.2 | GO:0043654 | recognition of apoptotic cell(GO:0043654) |
0.0 | 0.7 | GO:0051451 | myoblast migration(GO:0051451) |
0.0 | 1.2 | GO:0001829 | trophectodermal cell differentiation(GO:0001829) |
0.0 | 0.3 | GO:0046498 | S-adenosylhomocysteine metabolic process(GO:0046498) |
0.0 | 0.5 | GO:0035414 | negative regulation of catenin import into nucleus(GO:0035414) |
0.0 | 0.5 | GO:1990173 | protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173) |
0.0 | 0.4 | GO:0006265 | DNA topological change(GO:0006265) |
0.0 | 0.2 | GO:0035720 | intraciliary anterograde transport(GO:0035720) |
0.0 | 1.3 | GO:0046827 | positive regulation of protein export from nucleus(GO:0046827) |
0.0 | 1.6 | GO:0050982 | detection of mechanical stimulus(GO:0050982) |
0.0 | 0.5 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
0.0 | 0.3 | GO:0043922 | negative regulation by host of viral transcription(GO:0043922) |
0.0 | 0.5 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
0.0 | 0.9 | GO:0006471 | protein ADP-ribosylation(GO:0006471) |
0.0 | 0.4 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
0.0 | 0.1 | GO:0090309 | positive regulation of methylation-dependent chromatin silencing(GO:0090309) |
0.0 | 0.1 | GO:0002339 | B cell selection(GO:0002339) |
0.0 | 0.9 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
0.0 | 0.9 | GO:0003016 | respiratory system process(GO:0003016) |
0.0 | 1.0 | GO:0006099 | tricarboxylic acid cycle(GO:0006099) |
0.0 | 1.0 | GO:0071300 | cellular response to retinoic acid(GO:0071300) |
0.0 | 0.5 | GO:0033572 | transferrin transport(GO:0033572) |
0.0 | 0.5 | GO:0008090 | retrograde axonal transport(GO:0008090) |
0.0 | 0.0 | GO:1904884 | telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884) |
0.0 | 0.2 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
0.0 | 0.2 | GO:0014886 | transition between slow and fast fiber(GO:0014886) |
0.0 | 0.1 | GO:0006421 | asparaginyl-tRNA aminoacylation(GO:0006421) |
0.0 | 0.4 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
0.0 | 0.1 | GO:0016561 | protein import into peroxisome matrix, translocation(GO:0016561) |
0.0 | 0.6 | GO:0035025 | positive regulation of Rho protein signal transduction(GO:0035025) |
0.0 | 0.4 | GO:0007250 | activation of NF-kappaB-inducing kinase activity(GO:0007250) |
0.0 | 0.3 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
0.0 | 0.1 | GO:0019676 | ammonia assimilation cycle(GO:0019676) |
0.0 | 0.1 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
0.0 | 0.6 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
0.0 | 0.1 | GO:1902268 | negative regulation of polyamine transmembrane transport(GO:1902268) |
0.0 | 0.9 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
0.0 | 0.7 | GO:0051764 | actin crosslink formation(GO:0051764) |
0.0 | 0.3 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
0.0 | 0.2 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
0.0 | 0.2 | GO:0016584 | nucleosome positioning(GO:0016584) |
0.0 | 0.1 | GO:0030647 | polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598) |
0.0 | 0.5 | GO:0045722 | positive regulation of gluconeogenesis(GO:0045722) |
0.0 | 0.3 | GO:1990440 | positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440) |
0.0 | 0.1 | GO:2000346 | negative regulation of hepatocyte proliferation(GO:2000346) |
0.0 | 1.1 | GO:0031648 | protein destabilization(GO:0031648) |
0.0 | 0.8 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
0.0 | 0.2 | GO:0060347 | heart trabecula formation(GO:0060347) |
0.0 | 0.5 | GO:0016556 | mRNA modification(GO:0016556) |
0.0 | 0.3 | GO:0007202 | activation of phospholipase C activity(GO:0007202) |
0.0 | 0.1 | GO:0035521 | monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) |
0.0 | 0.3 | GO:0090435 | protein localization to nuclear envelope(GO:0090435) |
0.0 | 1.0 | GO:0048013 | ephrin receptor signaling pathway(GO:0048013) |
0.0 | 1.9 | GO:0051865 | protein autoubiquitination(GO:0051865) |
0.0 | 0.6 | GO:0010758 | regulation of macrophage chemotaxis(GO:0010758) |
0.0 | 0.1 | GO:0006780 | uroporphyrinogen III biosynthetic process(GO:0006780) |
0.0 | 2.5 | GO:0002028 | regulation of sodium ion transport(GO:0002028) |
0.0 | 1.0 | GO:0051693 | actin filament capping(GO:0051693) |
0.0 | 0.1 | GO:0042989 | sequestering of actin monomers(GO:0042989) |
0.0 | 0.2 | GO:0051152 | positive regulation of smooth muscle cell differentiation(GO:0051152) |
0.0 | 0.3 | GO:0009048 | dosage compensation by inactivation of X chromosome(GO:0009048) |
0.0 | 0.1 | GO:0060398 | regulation of growth hormone receptor signaling pathway(GO:0060398) |
0.0 | 0.6 | GO:0009060 | aerobic respiration(GO:0009060) |
0.0 | 0.1 | GO:0045654 | positive regulation of megakaryocyte differentiation(GO:0045654) |
0.0 | 0.7 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
0.0 | 3.1 | GO:0006338 | chromatin remodeling(GO:0006338) |
0.0 | 0.1 | GO:0036003 | positive regulation of transcription from RNA polymerase II promoter in response to stress(GO:0036003) |
0.0 | 0.3 | GO:0060261 | positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) |
0.0 | 0.3 | GO:0051900 | regulation of mitochondrial depolarization(GO:0051900) |
0.0 | 0.2 | GO:0060712 | spongiotrophoblast layer development(GO:0060712) |
0.0 | 0.1 | GO:0007525 | somatic muscle development(GO:0007525) |
0.0 | 0.1 | GO:1903546 | protein localization to photoreceptor outer segment(GO:1903546) |
0.0 | 0.4 | GO:0045663 | positive regulation of myoblast differentiation(GO:0045663) |
0.0 | 0.7 | GO:0060325 | face morphogenesis(GO:0060325) |
0.0 | 0.1 | GO:0021506 | anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995) |
0.0 | 0.5 | GO:0010800 | positive regulation of peptidyl-threonine phosphorylation(GO:0010800) |
0.0 | 1.2 | GO:0032092 | positive regulation of protein binding(GO:0032092) |
0.0 | 0.6 | GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I(GO:0002474) |
0.0 | 0.1 | GO:0001880 | Mullerian duct regression(GO:0001880) |
0.0 | 0.7 | GO:0008542 | visual learning(GO:0008542) |
0.0 | 0.2 | GO:0001682 | tRNA 5'-leader removal(GO:0001682) |
0.0 | 0.1 | GO:0075522 | IRES-dependent viral translational initiation(GO:0075522) |
0.0 | 0.5 | GO:0045599 | negative regulation of fat cell differentiation(GO:0045599) |
0.0 | 0.6 | GO:0007029 | endoplasmic reticulum organization(GO:0007029) |
0.0 | 0.4 | GO:0006829 | zinc II ion transport(GO:0006829) |
0.0 | 0.2 | GO:0090201 | negative regulation of release of cytochrome c from mitochondria(GO:0090201) |
0.0 | 0.2 | GO:0090036 | regulation of protein kinase C signaling(GO:0090036) |
0.0 | 0.5 | GO:0032456 | endocytic recycling(GO:0032456) |
0.0 | 0.6 | GO:0030500 | regulation of bone mineralization(GO:0030500) |
0.0 | 0.1 | GO:0019321 | pentose metabolic process(GO:0019321) |
0.0 | 0.1 | GO:0003334 | keratinocyte development(GO:0003334) |
0.0 | 0.7 | GO:0043154 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154) |
0.0 | 0.1 | GO:0031125 | rRNA 3'-end processing(GO:0031125) |
0.0 | 0.4 | GO:2000785 | regulation of autophagosome assembly(GO:2000785) |
0.0 | 2.8 | GO:0043010 | camera-type eye development(GO:0043010) |
0.0 | 1.8 | GO:0007266 | Rho protein signal transduction(GO:0007266) |
0.0 | 0.4 | GO:0001541 | ovarian follicle development(GO:0001541) |
0.0 | 0.2 | GO:1903846 | positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846) |
0.0 | 0.1 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) |
0.0 | 0.3 | GO:0000578 | embryonic axis specification(GO:0000578) |
0.0 | 0.3 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
0.0 | 0.4 | GO:0030833 | regulation of actin filament polymerization(GO:0030833) |
0.0 | 0.2 | GO:0051568 | histone H3-K4 methylation(GO:0051568) |
0.0 | 0.6 | GO:0043966 | histone H3 acetylation(GO:0043966) |
0.0 | 0.3 | GO:1901998 | toxin transport(GO:1901998) |
0.0 | 0.6 | GO:1904591 | positive regulation of protein import(GO:1904591) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.1 | 3.3 | GO:0070557 | PCNA-p21 complex(GO:0070557) |
0.8 | 3.1 | GO:0008623 | CHRAC(GO:0008623) |
0.5 | 2.9 | GO:0044305 | calyx of Held(GO:0044305) |
0.4 | 1.1 | GO:0098835 | presynaptic endosome(GO:0098830) presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) |
0.3 | 1.6 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
0.3 | 1.3 | GO:0060187 | cell pole(GO:0060187) |
0.3 | 1.1 | GO:0031983 | vesicle lumen(GO:0031983) |
0.3 | 1.3 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
0.2 | 1.7 | GO:0060053 | neurofilament cytoskeleton(GO:0060053) |
0.2 | 1.3 | GO:0033503 | HULC complex(GO:0033503) |
0.2 | 0.5 | GO:0071914 | prominosome(GO:0071914) |
0.2 | 1.2 | GO:0005726 | perichromatin fibrils(GO:0005726) |
0.2 | 0.8 | GO:0070876 | SOSS complex(GO:0070876) |
0.1 | 0.6 | GO:1990032 | parallel fiber(GO:1990032) |
0.1 | 0.7 | GO:0030891 | VCB complex(GO:0030891) |
0.1 | 1.8 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
0.1 | 0.4 | GO:0002142 | stereocilia ankle link complex(GO:0002142) |
0.1 | 0.5 | GO:0002111 | BRCA2-BRAF35 complex(GO:0002111) |
0.1 | 0.6 | GO:0070826 | paraferritin complex(GO:0070826) |
0.1 | 0.5 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
0.1 | 0.8 | GO:0042613 | MHC class II protein complex(GO:0042613) |
0.1 | 5.3 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
0.1 | 0.7 | GO:0005958 | DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) |
0.1 | 1.4 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
0.1 | 0.7 | GO:0036195 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
0.1 | 0.9 | GO:0030478 | actin cap(GO:0030478) |
0.1 | 0.3 | GO:0070695 | FHF complex(GO:0070695) |
0.1 | 3.2 | GO:0070469 | respiratory chain(GO:0070469) |
0.1 | 1.4 | GO:0031045 | dense core granule(GO:0031045) |
0.1 | 0.5 | GO:0031462 | Cul2-RING ubiquitin ligase complex(GO:0031462) |
0.1 | 0.9 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
0.1 | 0.7 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
0.1 | 0.2 | GO:0034657 | GID complex(GO:0034657) |
0.1 | 0.3 | GO:0002189 | ribose phosphate diphosphokinase complex(GO:0002189) |
0.1 | 1.4 | GO:0005640 | nuclear outer membrane(GO:0005640) |
0.1 | 0.4 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
0.1 | 1.8 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
0.1 | 1.7 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
0.1 | 0.4 | GO:0031258 | lamellipodium membrane(GO:0031258) |
0.1 | 0.4 | GO:1990130 | Iml1 complex(GO:1990130) |
0.1 | 0.3 | GO:0071008 | U2-type post-mRNA release spliceosomal complex(GO:0071008) |
0.1 | 2.6 | GO:0035861 | site of double-strand break(GO:0035861) |
0.1 | 0.6 | GO:0045261 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261) |
0.1 | 0.4 | GO:0097513 | myosin II filament(GO:0097513) |
0.1 | 0.7 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
0.1 | 0.5 | GO:0042382 | paraspeckles(GO:0042382) |
0.1 | 0.5 | GO:0097413 | Lewy body(GO:0097413) |
0.1 | 1.4 | GO:0030175 | filopodium(GO:0030175) |
0.1 | 1.1 | GO:0033276 | transcription factor TFTC complex(GO:0033276) |
0.1 | 1.9 | GO:0060077 | inhibitory synapse(GO:0060077) |
0.1 | 0.4 | GO:0071204 | histone pre-mRNA 3'end processing complex(GO:0071204) |
0.0 | 1.0 | GO:0045120 | pronucleus(GO:0045120) |
0.0 | 0.5 | GO:0001739 | sex chromatin(GO:0001739) |
0.0 | 0.7 | GO:0042788 | polysomal ribosome(GO:0042788) |
0.0 | 3.1 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
0.0 | 0.3 | GO:0090571 | RNA polymerase II transcription repressor complex(GO:0090571) |
0.0 | 0.6 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
0.0 | 1.4 | GO:0000788 | nuclear nucleosome(GO:0000788) |
0.0 | 0.3 | GO:0034750 | Scrib-APC-beta-catenin complex(GO:0034750) |
0.0 | 0.5 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
0.0 | 0.9 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
0.0 | 0.9 | GO:0005682 | U5 snRNP(GO:0005682) |
0.0 | 1.4 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
0.0 | 0.6 | GO:0033655 | host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655) |
0.0 | 0.1 | GO:0019815 | B cell receptor complex(GO:0019815) |
0.0 | 0.4 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
0.0 | 0.4 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
0.0 | 0.3 | GO:0097427 | microtubule bundle(GO:0097427) |
0.0 | 0.5 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
0.0 | 0.4 | GO:0000793 | condensed chromosome(GO:0000793) |
0.0 | 1.3 | GO:0002102 | podosome(GO:0002102) |
0.0 | 0.3 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
0.0 | 0.7 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
0.0 | 0.6 | GO:0005771 | multivesicular body(GO:0005771) |
0.0 | 0.3 | GO:0030057 | desmosome(GO:0030057) |
0.0 | 0.2 | GO:0000243 | commitment complex(GO:0000243) |
0.0 | 1.1 | GO:0031672 | A band(GO:0031672) |
0.0 | 0.4 | GO:0042101 | T cell receptor complex(GO:0042101) |
0.0 | 0.7 | GO:0031519 | PcG protein complex(GO:0031519) |
0.0 | 0.2 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
0.0 | 0.9 | GO:0043034 | costamere(GO:0043034) |
0.0 | 0.1 | GO:1990745 | EARP complex(GO:1990745) |
0.0 | 0.1 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
0.0 | 0.8 | GO:0000786 | nucleosome(GO:0000786) |
0.0 | 0.5 | GO:0032587 | ruffle membrane(GO:0032587) |
0.0 | 0.9 | GO:0030027 | lamellipodium(GO:0030027) |
0.0 | 0.2 | GO:0044666 | MLL3/4 complex(GO:0044666) |
0.0 | 0.4 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
0.0 | 2.0 | GO:0000792 | heterochromatin(GO:0000792) |
0.0 | 0.2 | GO:0042571 | immunoglobulin complex(GO:0019814) immunoglobulin complex, circulating(GO:0042571) |
0.0 | 0.2 | GO:0034719 | SMN-Sm protein complex(GO:0034719) |
0.0 | 0.2 | GO:0097542 | ciliary tip(GO:0097542) |
0.0 | 1.0 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
0.0 | 0.7 | GO:0031941 | filamentous actin(GO:0031941) |
0.0 | 0.1 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
0.0 | 4.4 | GO:0005938 | cell cortex(GO:0005938) |
0.0 | 0.1 | GO:0001520 | outer dense fiber(GO:0001520) |
0.0 | 1.1 | GO:0005581 | collagen trimer(GO:0005581) |
0.0 | 0.4 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
0.0 | 0.2 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
0.0 | 0.5 | GO:0005637 | nuclear inner membrane(GO:0005637) |
0.0 | 0.2 | GO:0031616 | spindle pole centrosome(GO:0031616) |
0.0 | 0.3 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
0.0 | 1.7 | GO:0005813 | centrosome(GO:0005813) |
0.0 | 0.1 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
0.0 | 0.8 | GO:0001669 | acrosomal vesicle(GO:0001669) |
0.0 | 0.6 | GO:0016529 | sarcoplasmic reticulum(GO:0016529) |
0.0 | 0.4 | GO:0055038 | recycling endosome membrane(GO:0055038) |
0.0 | 0.1 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
0.0 | 0.6 | GO:0005844 | polysome(GO:0005844) |
0.0 | 0.8 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.1 | 3.3 | GO:0019912 | cyclin-dependent protein kinase activating kinase activity(GO:0019912) |
1.0 | 2.9 | GO:0001565 | phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566) |
0.4 | 2.6 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
0.3 | 1.0 | GO:0017084 | glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202) |
0.3 | 0.9 | GO:0003953 | NAD+ nucleosidase activity(GO:0003953) |
0.3 | 1.4 | GO:0070330 | aromatase activity(GO:0070330) |
0.3 | 0.8 | GO:0000386 | second spliceosomal transesterification activity(GO:0000386) |
0.3 | 0.8 | GO:0004923 | leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924) |
0.2 | 1.0 | GO:0015220 | choline transmembrane transporter activity(GO:0015220) |
0.2 | 6.7 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.2 | 0.7 | GO:0004677 | DNA-dependent protein kinase activity(GO:0004677) |
0.2 | 3.6 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
0.2 | 1.3 | GO:0048101 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
0.2 | 0.6 | GO:0017099 | very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099) |
0.2 | 3.2 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
0.2 | 1.2 | GO:0034056 | estrogen response element binding(GO:0034056) |
0.2 | 1.0 | GO:0070579 | methylcytosine dioxygenase activity(GO:0070579) |
0.2 | 0.6 | GO:0004315 | 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) |
0.1 | 0.9 | GO:0001758 | retinal dehydrogenase activity(GO:0001758) |
0.1 | 0.9 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
0.1 | 1.7 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
0.1 | 0.7 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
0.1 | 0.4 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
0.1 | 0.4 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
0.1 | 0.7 | GO:0070728 | leucine binding(GO:0070728) |
0.1 | 0.2 | GO:0002161 | aminoacyl-tRNA editing activity(GO:0002161) |
0.1 | 1.0 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
0.1 | 0.6 | GO:0015086 | cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639) |
0.1 | 0.3 | GO:0030519 | snoRNP binding(GO:0030519) |
0.1 | 0.6 | GO:0043532 | angiostatin binding(GO:0043532) |
0.1 | 0.3 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
0.1 | 0.5 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
0.1 | 1.1 | GO:0031802 | type 5 metabotropic glutamate receptor binding(GO:0031802) |
0.1 | 0.6 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
0.1 | 1.4 | GO:0043495 | protein anchor(GO:0043495) |
0.1 | 1.0 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
0.1 | 2.6 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
0.1 | 0.8 | GO:0043140 | ATP-dependent 3'-5' DNA helicase activity(GO:0043140) |
0.1 | 1.1 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
0.1 | 1.5 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
0.1 | 0.3 | GO:0015140 | malate transmembrane transporter activity(GO:0015140) |
0.1 | 0.7 | GO:0001075 | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) |
0.1 | 0.8 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
0.1 | 0.6 | GO:0035662 | Toll-like receptor 4 binding(GO:0035662) |
0.1 | 0.6 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
0.1 | 0.5 | GO:0003910 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
0.1 | 0.2 | GO:0008515 | sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157) |
0.1 | 1.1 | GO:0031005 | filamin binding(GO:0031005) |
0.1 | 0.3 | GO:0004749 | ribose phosphate diphosphokinase activity(GO:0004749) |
0.1 | 0.6 | GO:0008417 | fucosyltransferase activity(GO:0008417) |
0.1 | 0.2 | GO:0071207 | histone pre-mRNA stem-loop binding(GO:0071207) |
0.1 | 1.1 | GO:0019215 | intermediate filament binding(GO:0019215) |
0.1 | 0.5 | GO:1990405 | protein antigen binding(GO:1990405) |
0.1 | 0.7 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
0.1 | 1.1 | GO:0005355 | glucose transmembrane transporter activity(GO:0005355) |
0.1 | 0.4 | GO:0003917 | DNA topoisomerase type I activity(GO:0003917) |
0.1 | 0.4 | GO:0008172 | S-methyltransferase activity(GO:0008172) |
0.1 | 2.3 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
0.1 | 0.4 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
0.1 | 0.3 | GO:0071987 | WD40-repeat domain binding(GO:0071987) |
0.1 | 0.4 | GO:0002135 | CTP binding(GO:0002135) |
0.1 | 0.3 | GO:0047275 | glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275) |
0.1 | 1.4 | GO:0042056 | chemoattractant activity(GO:0042056) |
0.1 | 0.3 | GO:0010385 | double-stranded methylated DNA binding(GO:0010385) |
0.1 | 0.5 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
0.1 | 0.3 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
0.1 | 1.2 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
0.1 | 0.6 | GO:0022848 | acetylcholine-gated cation channel activity(GO:0022848) |
0.1 | 0.4 | GO:0098519 | nucleotide phosphatase activity, acting on free nucleotides(GO:0098519) |
0.1 | 0.3 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
0.1 | 3.3 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
0.1 | 8.0 | GO:0016779 | nucleotidyltransferase activity(GO:0016779) |
0.1 | 0.3 | GO:0004719 | protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719) |
0.1 | 0.9 | GO:0051787 | misfolded protein binding(GO:0051787) |
0.1 | 2.7 | GO:0015485 | cholesterol binding(GO:0015485) |
0.1 | 0.5 | GO:0070097 | delta-catenin binding(GO:0070097) |
0.0 | 0.8 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
0.0 | 0.3 | GO:0061665 | SUMO ligase activity(GO:0061665) |
0.0 | 0.2 | GO:0004165 | dodecenoyl-CoA delta-isomerase activity(GO:0004165) |
0.0 | 0.2 | GO:0005483 | soluble NSF attachment protein activity(GO:0005483) |
0.0 | 0.3 | GO:0070492 | sialic acid binding(GO:0033691) oligosaccharide binding(GO:0070492) |
0.0 | 0.2 | GO:0035529 | NADH pyrophosphatase activity(GO:0035529) |
0.0 | 0.4 | GO:0017162 | aryl hydrocarbon receptor binding(GO:0017162) |
0.0 | 0.8 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
0.0 | 1.4 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
0.0 | 2.3 | GO:0001540 | beta-amyloid binding(GO:0001540) |
0.0 | 1.0 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
0.0 | 0.6 | GO:0005123 | death receptor binding(GO:0005123) |
0.0 | 0.3 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
0.0 | 0.6 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
0.0 | 0.3 | GO:1990446 | U1 snRNP binding(GO:1990446) |
0.0 | 0.7 | GO:0017049 | GTP-Rho binding(GO:0017049) |
0.0 | 0.6 | GO:0005537 | mannose binding(GO:0005537) |
0.0 | 0.6 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
0.0 | 1.6 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
0.0 | 0.7 | GO:0031489 | myosin V binding(GO:0031489) |
0.0 | 0.8 | GO:0035613 | RNA stem-loop binding(GO:0035613) |
0.0 | 0.3 | GO:0004128 | cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128) |
0.0 | 0.5 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
0.0 | 2.5 | GO:0015078 | hydrogen ion transmembrane transporter activity(GO:0015078) |
0.0 | 0.3 | GO:0097027 | ubiquitin-protein transferase activator activity(GO:0097027) |
0.0 | 0.1 | GO:0016880 | acid-ammonia (or amide) ligase activity(GO:0016880) |
0.0 | 0.2 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
0.0 | 0.1 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
0.0 | 3.4 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
0.0 | 0.2 | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) |
0.0 | 0.2 | GO:0031490 | chromatin DNA binding(GO:0031490) |
0.0 | 1.4 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
0.0 | 0.4 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
0.0 | 2.1 | GO:0004721 | phosphoprotein phosphatase activity(GO:0004721) |
0.0 | 1.0 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
0.0 | 0.3 | GO:0015250 | water channel activity(GO:0015250) |
0.0 | 0.8 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
0.0 | 0.7 | GO:0042605 | peptide antigen binding(GO:0042605) |
0.0 | 0.7 | GO:0097602 | cullin family protein binding(GO:0097602) |
0.0 | 1.1 | GO:0017022 | myosin binding(GO:0017022) |
0.0 | 0.3 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
0.0 | 1.1 | GO:0032452 | histone demethylase activity(GO:0032452) |
0.0 | 0.3 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
0.0 | 4.1 | GO:0051015 | actin filament binding(GO:0051015) |
0.0 | 0.1 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
0.0 | 0.2 | GO:0048185 | activin binding(GO:0048185) |
0.0 | 0.2 | GO:0016427 | tRNA (cytosine) methyltransferase activity(GO:0016427) |
0.0 | 0.4 | GO:0000030 | mannosyltransferase activity(GO:0000030) |
0.0 | 0.5 | GO:0032183 | SUMO binding(GO:0032183) |
0.0 | 1.4 | GO:0002039 | p53 binding(GO:0002039) |
0.0 | 0.4 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
0.0 | 0.1 | GO:0016655 | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655) |
0.0 | 5.3 | GO:0061659 | ubiquitin-like protein ligase activity(GO:0061659) |
0.0 | 0.5 | GO:0042805 | actinin binding(GO:0042805) |
0.0 | 0.6 | GO:0017091 | AU-rich element binding(GO:0017091) |
0.0 | 0.5 | GO:0042169 | SH2 domain binding(GO:0042169) |
0.0 | 0.1 | GO:0004852 | uroporphyrinogen-III synthase activity(GO:0004852) |
0.0 | 0.7 | GO:0005179 | hormone activity(GO:0005179) |
0.0 | 1.1 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
0.0 | 0.5 | GO:0046875 | ephrin receptor binding(GO:0046875) |
0.0 | 1.0 | GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980) |
0.0 | 0.3 | GO:0035497 | cAMP response element binding(GO:0035497) |
0.0 | 0.3 | GO:0003785 | actin monomer binding(GO:0003785) |
0.0 | 0.2 | GO:0004526 | ribonuclease P activity(GO:0004526) |
0.0 | 0.2 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
0.0 | 0.2 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
0.0 | 0.6 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
0.0 | 0.7 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
0.0 | 3.3 | GO:0008017 | microtubule binding(GO:0008017) |
0.0 | 0.3 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
0.0 | 13.3 | GO:0043565 | sequence-specific DNA binding(GO:0043565) |
0.0 | 0.1 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.0 | 0.3 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
0.0 | 0.5 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
0.0 | 0.2 | GO:0008188 | neuropeptide receptor activity(GO:0008188) |
0.0 | 0.3 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.0 | 0.3 | GO:0016417 | S-acyltransferase activity(GO:0016417) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 3.6 | SA_G2_AND_M_PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
0.1 | 2.8 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
0.1 | 2.1 | PID_P38_MK2_PATHWAY | p38 signaling mediated by MAPKAP kinases |
0.1 | 2.7 | PID_CD40_PATHWAY | CD40/CD40L signaling |
0.1 | 1.0 | SA_B_CELL_RECEPTOR_COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
0.1 | 1.6 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
0.0 | 1.8 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
0.0 | 3.2 | PID_TRKR_PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
0.0 | 3.1 | PID_RAC1_REG_PATHWAY | Regulation of RAC1 activity |
0.0 | 1.1 | PID_WNT_NONCANONICAL_PATHWAY | Noncanonical Wnt signaling pathway |
0.0 | 1.6 | PID_ILK_PATHWAY | Integrin-linked kinase signaling |
0.0 | 0.6 | PID_HIF1A_PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
0.0 | 1.6 | PID_SYNDECAN_1_PATHWAY | Syndecan-1-mediated signaling events |
0.0 | 0.8 | PID_FRA_PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
0.0 | 0.7 | PID_IL2_PI3K_PATHWAY | IL2 signaling events mediated by PI3K |
0.0 | 0.3 | PID_ALK2_PATHWAY | ALK2 signaling events |
0.0 | 0.5 | PID_EPHA_FWDPATHWAY | EPHA forward signaling |
0.0 | 1.9 | PID_AR_TF_PATHWAY | Regulation of Androgen receptor activity |
0.0 | 0.7 | PID_DNA_PK_PATHWAY | DNA-PK pathway in nonhomologous end joining |
0.0 | 0.6 | PID_ARF_3PATHWAY | Arf1 pathway |
0.0 | 0.3 | PID_BETA_CATENIN_DEG_PATHWAY | Degradation of beta catenin |
0.0 | 1.4 | PID_TELOMERASE_PATHWAY | Regulation of Telomerase |
0.0 | 0.7 | PID_RHOA_REG_PATHWAY | Regulation of RhoA activity |
0.0 | 0.6 | PID_RAS_PATHWAY | Regulation of Ras family activation |
0.0 | 0.4 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
0.0 | 0.3 | PID_SMAD2_3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
0.0 | 0.5 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
0.0 | 0.1 | SA_REG_CASCADE_OF_CYCLIN_EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
0.0 | 0.4 | PID_PI3KCI_PATHWAY | Class I PI3K signaling events |
0.0 | 1.2 | PID_MYC_ACTIV_PATHWAY | Validated targets of C-MYC transcriptional activation |
0.0 | 0.3 | PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY | Signaling mediated by p38-alpha and p38-beta |
0.0 | 0.6 | PID_P75_NTR_PATHWAY | p75(NTR)-mediated signaling |
0.0 | 0.2 | PID_GLYPICAN_1PATHWAY | Glypican 1 network |
0.0 | 0.3 | PID_BARD1_PATHWAY | BARD1 signaling events |
0.0 | 0.6 | PID_AR_PATHWAY | Coregulation of Androgen receptor activity |
0.0 | 0.4 | PID_PDGFRB_PATHWAY | PDGFR-beta signaling pathway |
0.0 | 0.3 | PID_ATF2_PATHWAY | ATF-2 transcription factor network |
0.0 | 0.3 | PID_TCPTP_PATHWAY | Signaling events mediated by TCPTP |
0.0 | 0.2 | PID_EPHRINB_REV_PATHWAY | Ephrin B reverse signaling |
0.0 | 0.3 | PID_ATR_PATHWAY | ATR signaling pathway |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 3.4 | REACTOME_CS_DS_DEGRADATION | Genes involved in CS/DS degradation |
0.2 | 3.4 | REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
0.1 | 1.2 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
0.1 | 3.1 | REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL | Genes involved in AKT phosphorylates targets in the cytosol |
0.1 | 0.9 | REACTOME_PLATELET_CALCIUM_HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
0.1 | 3.2 | REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
0.1 | 0.6 | REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
0.1 | 3.2 | REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS | Genes involved in O-linked glycosylation of mucins |
0.1 | 2.1 | REACTOME_SMOOTH_MUSCLE_CONTRACTION | Genes involved in Smooth Muscle Contraction |
0.1 | 4.4 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | Genes involved in NRAGE signals death through JNK |
0.1 | 0.4 | REACTOME_THE_NLRP3_INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
0.1 | 1.3 | REACTOME_CGMP_EFFECTS | Genes involved in cGMP effects |
0.0 | 0.5 | REACTOME_PURINE_CATABOLISM | Genes involved in Purine catabolism |
0.0 | 0.7 | REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS | Genes involved in Regulation of gene expression in beta cells |
0.0 | 1.4 | REACTOME_ERK_MAPK_TARGETS | Genes involved in ERK/MAPK targets |
0.0 | 0.8 | REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS | Genes involved in Prolonged ERK activation events |
0.0 | 0.7 | REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY | Genes involved in Notch-HLH transcription pathway |
0.0 | 0.4 | REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
0.0 | 0.9 | REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
0.0 | 0.5 | REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
0.0 | 0.7 | REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
0.0 | 0.7 | REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
0.0 | 0.9 | REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
0.0 | 0.6 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI | Genes involved in N-glycan antennae elongation in the medial/trans-Golgi |
0.0 | 0.6 | REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
0.0 | 0.5 | REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D | Genes involved in Metabolism of steroid hormones and vitamins A and D |
0.0 | 0.3 | REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
0.0 | 0.7 | REACTOME_DOUBLE_STRAND_BREAK_REPAIR | Genes involved in Double-Strand Break Repair |
0.0 | 0.5 | REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |
0.0 | 0.8 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
0.0 | 0.5 | REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
0.0 | 0.9 | REACTOME_RNA_POL_I_PROMOTER_OPENING | Genes involved in RNA Polymerase I Promoter Opening |
0.0 | 0.1 | REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
0.0 | 0.5 | REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |
0.0 | 0.3 | REACTOME_ZINC_TRANSPORTERS | Genes involved in Zinc transporters |
0.0 | 0.4 | REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
0.0 | 0.2 | REACTOME_EGFR_DOWNREGULATION | Genes involved in EGFR downregulation |
0.0 | 0.6 | REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
0.0 | 0.4 | REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
0.0 | 0.4 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
0.0 | 0.2 | REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
0.0 | 0.2 | REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
0.0 | 0.5 | REACTOME_MRNA_SPLICING_MINOR_PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
0.0 | 0.3 | REACTOME_SULFUR_AMINO_ACID_METABOLISM | Genes involved in Sulfur amino acid metabolism |
0.0 | 0.9 | REACTOME_MRNA_SPLICING | Genes involved in mRNA Splicing |