Motif ID: Atf7_E4f1

Z-value: 1.432

Transcription factors associated with Atf7_E4f1:

Gene SymbolEntrez IDGene Name
Atf7 ENSMUSG00000052414.9 Atf7
Atf7 ENSMUSG00000071584.1 Atf7
E4f1 ENSMUSG00000024137.8 E4f1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Atf7mm10_v2_chr15_-_102529025_102529025-0.462.2e-03Click!
E4f1mm10_v2_chr17_-_24455265_24455345-0.296.4e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Atf7_E4f1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_59260878 13.511 ENSMUST00000026084.3
Slc18a2
solute carrier family 18 (vesicular monoamine), member 2
chr3_-_36571952 10.035 ENSMUST00000029270.3
Ccna2
cyclin A2
chr3_+_67374116 9.424 ENSMUST00000061322.8
Mlf1
myeloid leukemia factor 1
chr8_+_116921735 9.372 ENSMUST00000034205.4
Cenpn
centromere protein N
chr4_+_111720187 8.990 ENSMUST00000084354.3
Spata6
spermatogenesis associated 6
chr3_+_67374091 8.689 ENSMUST00000077916.5
Mlf1
myeloid leukemia factor 1
chr9_-_20976762 8.548 ENSMUST00000054197.5
S1pr2
sphingosine-1-phosphate receptor 2
chr6_-_23248264 8.509 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chrX_-_60893430 8.375 ENSMUST00000135107.2
Sox3
SRY-box containing gene 3
chr3_+_135212557 8.256 ENSMUST00000062893.7
Cenpe
centromere protein E
chr3_+_40800054 8.127 ENSMUST00000168287.1
Plk4
polo-like kinase 4
chr17_-_71526819 7.973 ENSMUST00000024851.9
Ndc80
NDC80 homolog, kinetochore complex component (S. cerevisiae)
chr1_-_71653162 7.676 ENSMUST00000055226.6
Fn1
fibronectin 1
chr13_+_8885501 7.542 ENSMUST00000169314.2
Idi1
isopentenyl-diphosphate delta isomerase
chr13_-_23761223 7.226 ENSMUST00000102964.2
Hist1h4a
histone cluster 1, H4a
chr13_+_23531044 6.976 ENSMUST00000102972.3
Hist1h4h
histone cluster 1, H4h
chr16_-_23890805 6.968 ENSMUST00000004480.3
Sst
somatostatin
chr3_-_145649970 6.581 ENSMUST00000029846.3
Cyr61
cysteine rich protein 61
chr15_+_99074968 6.580 ENSMUST00000039665.6
Troap
trophinin associated protein
chrX_+_170009659 6.389 ENSMUST00000179760.1
Gm21887
predicted gene, 21887
chr13_+_8885937 6.313 ENSMUST00000177397.1
ENSMUST00000177400.1
ENSMUST00000177447.1
Idi1


isopentenyl-diphosphate delta isomerase


chr12_+_112644828 6.068 ENSMUST00000021728.4
ENSMUST00000109755.3
Siva1

SIVA1, apoptosis-inducing factor

chr7_-_144939823 5.901 ENSMUST00000093962.4
Ccnd1
cyclin D1
chr1_+_95313607 5.889 ENSMUST00000059975.6
Fam174a
family with sequence similarity 174, member A
chr4_+_141301228 5.544 ENSMUST00000006614.2
Epha2
Eph receptor A2
chr12_-_69159109 5.459 ENSMUST00000037023.8
Rps29
ribosomal protein S29
chr17_+_34982154 5.456 ENSMUST00000173004.1
Lsm2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr2_+_105668888 5.446 ENSMUST00000111086.4
ENSMUST00000111087.3
Pax6

paired box gene 6

chr17_+_36958623 5.380 ENSMUST00000173814.1
Znrd1as
Znrd1 antisense
chr2_+_109280738 5.353 ENSMUST00000028527.7
Kif18a
kinesin family member 18A
chr17_+_34982099 5.290 ENSMUST00000007266.7
Lsm2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr3_+_89459118 5.235 ENSMUST00000029564.5
Pmvk
phosphomevalonate kinase
chr17_-_36958437 5.118 ENSMUST00000113669.2
Znrd1
zinc ribbon domain containing, 1
chr5_-_106458440 5.114 ENSMUST00000086795.6
Barhl2
BarH-like 2 (Drosophila)
chr10_-_30200492 5.086 ENSMUST00000099985.4
Cenpw
centromere protein W
chr4_-_97584605 4.876 ENSMUST00000107067.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr5_+_125389284 4.820 ENSMUST00000100700.2
Gm10382
predicted gene 10382
chr9_-_96478660 4.803 ENSMUST00000057500.4
Rnf7
ring finger protein 7
chr17_-_36958206 4.789 ENSMUST00000172823.1
Znrd1
zinc ribbon domain containing, 1
chr7_+_45718121 4.760 ENSMUST00000135500.2
Rpl18
ribosomal protein L18
chr17_-_36958533 4.743 ENSMUST00000172518.1
Znrd1
zinc ribbon domain containing, 1
chr4_-_97584612 4.695 ENSMUST00000107068.2
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr15_-_50889691 4.641 ENSMUST00000165201.2
ENSMUST00000184458.1
Trps1

trichorhinophalangeal syndrome I (human)

chr15_+_79516396 4.574 ENSMUST00000010974.7
Kdelr3
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr11_-_88718223 4.554 ENSMUST00000107909.1
Msi2
musashi RNA-binding protein 2
chr15_+_34238026 4.499 ENSMUST00000022867.3
Laptm4b
lysosomal-associated protein transmembrane 4B
chr17_+_36958571 4.461 ENSMUST00000040177.6
Znrd1as
Znrd1 antisense
chr1_+_74791516 4.322 ENSMUST00000006718.8
Wnt10a
wingless related MMTV integration site 10a
chr9_-_96478596 4.312 ENSMUST00000071301.4
Rnf7
ring finger protein 7
chr7_+_45718058 4.235 ENSMUST00000072503.6
Rpl18
ribosomal protein L18
chr7_-_25250720 4.162 ENSMUST00000116343.2
ENSMUST00000045847.8
Erf

Ets2 repressor factor

chr17_+_34981847 4.158 ENSMUST00000114011.4
Lsm2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr11_+_69324069 4.070 ENSMUST00000060956.6
ENSMUST00000108662.1
Trappc1

trafficking protein particle complex 1

chr3_-_127553233 3.978 ENSMUST00000029588.5
Larp7
La ribonucleoprotein domain family, member 7
chr2_-_127133909 3.946 ENSMUST00000110387.3
Ncaph
non-SMC condensin I complex, subunit H
chr11_+_69324055 3.906 ENSMUST00000102601.3
Trappc1
trafficking protein particle complex 1
chr1_+_175880775 3.882 ENSMUST00000039725.6
Exo1
exonuclease 1
chr17_-_31277327 3.856 ENSMUST00000024832.7
Rsph1
radial spoke head 1 homolog (Chlamydomonas)
chr2_-_132253227 3.763 ENSMUST00000028817.6
Pcna
proliferating cell nuclear antigen
chrX_+_106187100 3.750 ENSMUST00000081593.6
Pgk1
phosphoglycerate kinase 1
chr10_+_79682169 3.736 ENSMUST00000020550.5
Cdc34
cell division cycle 34
chr7_-_118533298 3.648 ENSMUST00000098090.3
ENSMUST00000032887.3
Coq7

demethyl-Q 7

chr4_-_134245579 3.646 ENSMUST00000030644.7
Zfp593
zinc finger protein 593
chr3_+_89459325 3.642 ENSMUST00000107410.1
Pmvk
phosphomevalonate kinase
chr11_+_69323963 3.613 ENSMUST00000102602.1
Trappc1
trafficking protein particle complex 1
chr6_-_23132981 3.587 ENSMUST00000031707.7
Aass
aminoadipate-semialdehyde synthase
chr7_+_3703979 3.563 ENSMUST00000006496.8
Rps9
ribosomal protein S9
chr10_+_121033960 3.555 ENSMUST00000020439.4
ENSMUST00000175867.1
Wif1

Wnt inhibitory factor 1

chr10_+_96616998 3.488 ENSMUST00000038377.7
Btg1
B cell translocation gene 1, anti-proliferative
chr6_+_113531675 3.478 ENSMUST00000036340.5
ENSMUST00000101051.2
Fancd2

Fanconi anemia, complementation group D2

chr11_-_69980468 3.446 ENSMUST00000143175.1
Elp5
elongator acetyltransferase complex subunit 5
chr8_+_92674289 3.443 ENSMUST00000034185.6
Irx6
Iroquois related homeobox 6 (Drosophila)
chr8_+_45885479 3.439 ENSMUST00000034053.5
Pdlim3
PDZ and LIM domain 3
chr4_-_117182623 3.434 ENSMUST00000065896.2
Kif2c
kinesin family member 2C
chr5_+_114444266 3.414 ENSMUST00000043760.8
ENSMUST00000112239.2
ENSMUST00000125650.1
Mvk


mevalonate kinase


chr11_+_59208321 3.349 ENSMUST00000020719.6
2310033P09Rik
RIKEN cDNA 2310033P09 gene
chr2_-_150668198 3.308 ENSMUST00000028944.3
Acss1
acyl-CoA synthetase short-chain family member 1
chr2_-_57114970 3.282 ENSMUST00000028166.2
Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr11_-_6444352 3.241 ENSMUST00000093346.5
ENSMUST00000109737.2
H2afv

H2A histone family, member V

chr3_+_40800013 3.233 ENSMUST00000026858.5
ENSMUST00000170825.1
Plk4

polo-like kinase 4

chr4_+_130360132 3.226 ENSMUST00000105994.3
Snrnp40
small nuclear ribonucleoprotein 40 (U5)
chr11_-_69920892 3.210 ENSMUST00000152589.1
ENSMUST00000108612.1
ENSMUST00000108611.1
Eif5a


eukaryotic translation initiation factor 5A


chr7_-_118584669 3.191 ENSMUST00000044195.4
Tmc7
transmembrane channel-like gene family 7
chr12_+_108792946 3.165 ENSMUST00000021692.7
Yy1
YY1 transcription factor
chr1_-_134079114 3.151 ENSMUST00000020692.6
Btg2
B cell translocation gene 2, anti-proliferative
chr4_-_131838231 3.136 ENSMUST00000030741.2
ENSMUST00000105987.2
Ptpru

protein tyrosine phosphatase, receptor type, U

chr18_+_82914632 3.099 ENSMUST00000071233.6
Zfp516
zinc finger protein 516
chr6_+_83034173 3.035 ENSMUST00000000707.2
ENSMUST00000101257.3
Loxl3

lysyl oxidase-like 3

chr1_-_191575534 2.920 ENSMUST00000027933.5
Dtl
denticleless homolog (Drosophila)
chr7_+_3704307 2.875 ENSMUST00000108624.1
ENSMUST00000126562.1
Rps9

ribosomal protein S9

chr11_-_76243610 2.869 ENSMUST00000164022.1
ENSMUST00000168055.1
ENSMUST00000169701.1
Glod4


glyoxalase domain containing 4


chr11_-_78165521 2.862 ENSMUST00000017530.3
Traf4
TNF receptor associated factor 4
chr10_-_128176568 2.856 ENSMUST00000092033.2
Rbms2
RNA binding motif, single stranded interacting protein 2
chr2_+_105668935 2.818 ENSMUST00000142772.1
Pax6
paired box gene 6
chr11_+_76243715 2.816 ENSMUST00000040577.4
Rnmtl1
RNA methyltransferase like 1
chr7_+_3704025 2.806 ENSMUST00000108623.1
ENSMUST00000139818.1
ENSMUST00000108625.1
Rps9


ribosomal protein S9


chr11_-_69921057 2.775 ENSMUST00000108609.1
ENSMUST00000108608.1
ENSMUST00000164359.1
Eif5a


eukaryotic translation initiation factor 5A


chr6_-_50566535 2.757 ENSMUST00000161401.1
Cycs
cytochrome c, somatic
chr4_+_42735545 2.717 ENSMUST00000068158.3
4930578G10Rik
RIKEN cDNA 4930578G10 gene
chr17_+_23679363 2.673 ENSMUST00000024699.2
Cldn6
claudin 6
chr16_-_33967032 2.628 ENSMUST00000023510.6
Umps
uridine monophosphate synthetase
chr8_-_92355764 2.602 ENSMUST00000180102.1
ENSMUST00000179421.1
ENSMUST00000179222.1
ENSMUST00000179029.1
4933436C20Rik



RIKEN cDNA 4933436C20 gene



chr18_+_11657349 2.585 ENSMUST00000047322.6
Rbbp8
retinoblastoma binding protein 8
chr8_-_84662841 2.581 ENSMUST00000060427.4
Ier2
immediate early response 2
chr5_+_9100681 2.563 ENSMUST00000115365.1
Tmem243
transmembrane protein 243, mitochondrial
chr17_-_31658729 2.563 ENSMUST00000166526.1
ENSMUST00000014684.4
U2af1

U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1

chrX_-_8145713 2.548 ENSMUST00000115615.2
ENSMUST00000115616.1
ENSMUST00000115621.2
Rbm3


RNA binding motif protein 3


chr13_+_22043189 2.544 ENSMUST00000110452.1
Hist1h2bj
histone cluster 1, H2bj
chr8_+_92674826 2.539 ENSMUST00000167261.2
Irx6
Iroquois related homeobox 6 (Drosophila)
chr7_+_139389072 2.532 ENSMUST00000106098.1
ENSMUST00000026550.7
Inpp5a

inositol polyphosphate-5-phosphatase A

chr19_+_37376359 2.518 ENSMUST00000012587.3
Kif11
kinesin family member 11
chr1_+_92831614 2.514 ENSMUST00000045970.6
Gpc1
glypican 1
chr12_+_52097737 2.511 ENSMUST00000040090.9
Nubpl
nucleotide binding protein-like
chr14_-_87141206 2.507 ENSMUST00000022599.7
Diap3
diaphanous homolog 3 (Drosophila)
chr4_+_3938888 2.493 ENSMUST00000121110.1
ENSMUST00000108386.1
ENSMUST00000149544.1
Chchd7


coiled-coil-helix-coiled-coil-helix domain containing 7


chr1_+_71652837 2.484 ENSMUST00000097699.2
Apol7d
apolipoprotein L 7d
chr10_+_80141457 2.483 ENSMUST00000105367.1
Atp5d
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr11_+_84525669 2.482 ENSMUST00000126072.1
ENSMUST00000128121.1
1500016L03Rik

RIKEN cDNA 1500016L03 gene

chr7_+_117380937 2.471 ENSMUST00000032892.5
Xylt1
xylosyltransferase 1
chr11_+_84525647 2.460 ENSMUST00000134800.1
1500016L03Rik
RIKEN cDNA 1500016L03 gene
chr11_-_69323768 2.428 ENSMUST00000092973.5
Cntrob
centrobin, centrosomal BRCA2 interacting protein
chr3_-_45378206 2.422 ENSMUST00000181047.1
2610316D01Rik
RIKEN cDNA 2610316D01 gene
chr13_-_22042949 2.375 ENSMUST00000091741.4
Hist1h2ag
histone cluster 1, H2ag
chr3_-_108840477 2.336 ENSMUST00000106596.3
ENSMUST00000102621.4
Stxbp3a

syntaxin binding protein 3A

chrX_+_112311334 2.314 ENSMUST00000026599.3
ENSMUST00000113415.1
Apool

apolipoprotein O-like

chr5_+_142960343 2.289 ENSMUST00000031565.8
Fscn1
fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)
chr19_-_4625612 2.285 ENSMUST00000025823.3
Rce1
RCE1 homolog, prenyl protein peptidase (S. cerevisiae)
chr2_-_157007039 2.274 ENSMUST00000103129.2
ENSMUST00000103130.1
Dsn1

DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)

chr11_+_40733936 2.198 ENSMUST00000127382.1
Nudcd2
NudC domain containing 2
chr11_-_76243687 2.198 ENSMUST00000017430.5
Glod4
glyoxalase domain containing 4
chr10_+_44268328 2.193 ENSMUST00000039286.4
Atg5
autophagy related 5
chr14_-_69284982 2.190 ENSMUST00000183882.1
ENSMUST00000037064.4
Slc25a37

solute carrier family 25, member 37

chr11_+_40733639 2.180 ENSMUST00000020578.4
Nudcd2
NudC domain containing 2
chr14_-_87141114 2.162 ENSMUST00000168889.1
Diap3
diaphanous homolog 3 (Drosophila)
chr2_+_156065180 2.139 ENSMUST00000038860.5
Spag4
sperm associated antigen 4
chr7_-_30664986 2.089 ENSMUST00000019697.8
Haus5
HAUS augmin-like complex, subunit 5
chr17_+_84511832 2.069 ENSMUST00000047206.5
Plekhh2
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr6_-_49264014 2.050 ENSMUST00000031841.7
Tra2a
transformer 2 alpha homolog (Drosophila)
chr11_-_97782409 2.046 ENSMUST00000103146.4
Rpl23
ribosomal protein L23
chr1_-_92473801 2.031 ENSMUST00000027478.6
Ndufa10
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10
chr7_+_102441685 2.026 ENSMUST00000033283.9
Rrm1
ribonucleotide reductase M1
chr7_-_13034722 2.018 ENSMUST00000005711.4
Chmp2a
charged multivesicular body protein 2A
chr15_-_81399594 2.017 ENSMUST00000023039.8
St13
suppression of tumorigenicity 13
chr5_-_110653348 2.016 ENSMUST00000042147.5
Noc4l
nucleolar complex associated 4 homolog (S. cerevisiae)
chr8_+_75109528 2.006 ENSMUST00000164309.1
Mcm5
minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)
chr11_+_22990519 1.990 ENSMUST00000173867.1
ENSMUST00000020562.4
Cct4

chaperonin containing Tcp1, subunit 4 (delta)

chr8_-_70873477 1.989 ENSMUST00000007865.5
Ccdc124
coiled-coil domain containing 124
chr11_-_69921190 1.986 ENSMUST00000108607.1
Eif5a
eukaryotic translation initiation factor 5A
chr2_+_164746028 1.977 ENSMUST00000109327.3
Dnttip1
deoxynucleotidyltransferase, terminal, interacting protein 1
chr9_+_48495345 1.923 ENSMUST00000048824.7
Gm5617
predicted gene 5617
chr5_-_108434373 1.867 ENSMUST00000049628.9
ENSMUST00000118632.1
Atp5k

ATP synthase, H+ transporting, mitochondrial F1F0 complex, subunit e

chr9_-_103364970 1.864 ENSMUST00000116517.2
Cdv3
carnitine deficiency-associated gene expressed in ventricle 3
chr10_-_128493834 1.857 ENSMUST00000164181.1
Myl6
myosin, light polypeptide 6, alkali, smooth muscle and non-muscle
chr15_-_81400043 1.853 ENSMUST00000172107.1
ENSMUST00000169204.1
ENSMUST00000163382.1
St13


suppression of tumorigenicity 13


chr2_+_164745979 1.841 ENSMUST00000017443.7
ENSMUST00000109326.3
Dnttip1

deoxynucleotidyltransferase, terminal, interacting protein 1

chr8_-_115707778 1.823 ENSMUST00000109104.1
Maf
avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog
chr14_+_47472547 1.820 ENSMUST00000168833.1
ENSMUST00000163324.1
ENSMUST00000043112.7
Fbxo34


F-box protein 34


chr16_-_4077778 1.806 ENSMUST00000006137.8
Trap1
TNF receptor-associated protein 1
chr8_+_70302761 1.766 ENSMUST00000150968.1
Cope
coatomer protein complex, subunit epsilon
chr7_-_137314394 1.764 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
Ebf3



early B cell factor 3



chr6_+_135065651 1.763 ENSMUST00000050104.7
Gprc5a
G protein-coupled receptor, family C, group 5, member A
chr14_+_47472628 1.758 ENSMUST00000095941.2
Fbxo34
F-box protein 34
chr11_-_69921329 1.757 ENSMUST00000108613.3
ENSMUST00000043419.3
ENSMUST00000070996.4
Eif5a


eukaryotic translation initiation factor 5A


chr3_-_146108047 1.738 ENSMUST00000160285.1
Wdr63
WD repeat domain 63
chr4_+_3938904 1.731 ENSMUST00000120732.1
ENSMUST00000041122.4
ENSMUST00000121651.1
ENSMUST00000121210.1
ENSMUST00000119307.1
ENSMUST00000123769.1
Chchd7





coiled-coil-helix-coiled-coil-helix domain containing 7





chr11_-_97782377 1.731 ENSMUST00000128801.1
Rpl23
ribosomal protein L23
chr5_-_5559521 1.731 ENSMUST00000088842.4
ENSMUST00000115441.2
Gtpbp10

GTP-binding protein 10 (putative)

chr11_-_87108656 1.727 ENSMUST00000051395.8
Prr11
proline rich 11
chr8_+_72135247 1.703 ENSMUST00000003575.9
Tpm4
tropomyosin 4
chr4_+_155704789 1.702 ENSMUST00000030905.2
Ssu72
Ssu72 RNA polymerase II CTD phosphatase homolog (yeast)
chr3_-_138143352 1.699 ENSMUST00000098580.2
Mttp
microsomal triglyceride transfer protein
chr11_-_40733373 1.690 ENSMUST00000020579.8
Hmmr
hyaluronan mediated motility receptor (RHAMM)
chr15_+_79347534 1.690 ENSMUST00000096350.3
Maff
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
chr6_+_124931378 1.674 ENSMUST00000032214.7
ENSMUST00000180095.1
Mlf2

myeloid leukemia factor 2

chr3_+_138143429 1.667 ENSMUST00000040321.6
Trmt10a
tRNA methyltransferase 10A
chr7_+_141447645 1.656 ENSMUST00000106004.1
ENSMUST00000106003.1
Rplp2

ribosomal protein, large P2

chr16_-_4790220 1.654 ENSMUST00000118703.1
Cdip1
cell death inducing Trp53 target 1
chr2_-_26140468 1.643 ENSMUST00000133808.1
C330006A16Rik
RIKEN cDNA C330006A16 gene
chr10_+_72654873 1.634 ENSMUST00000105431.1
ENSMUST00000160337.1
Zwint

ZW10 interactor

chr2_-_23155864 1.627 ENSMUST00000028119.6
Mastl
microtubule associated serine/threonine kinase-like
chr9_+_22411515 1.618 ENSMUST00000058868.7
9530077C05Rik
RIKEN cDNA 9530077C05 gene
chr11_+_59948206 1.615 ENSMUST00000081980.6
Med9
mediator of RNA polymerase II transcription, subunit 9 homolog (yeast)
chr10_+_13008442 1.613 ENSMUST00000105139.3
Sf3b5
splicing factor 3b, subunit 5
chr17_-_33824346 1.601 ENSMUST00000173879.1
ENSMUST00000166693.2
ENSMUST00000173019.1
ENSMUST00000087342.6
ENSMUST00000173844.1
Rps28




ribosomal protein S28




chr8_-_92356103 1.595 ENSMUST00000034183.3
4933436C20Rik
RIKEN cDNA 4933436C20 gene
chr2_-_127788854 1.583 ENSMUST00000028857.7
ENSMUST00000110357.1
Nphp1

nephronophthisis 1 (juvenile) homolog (human)

chr17_-_27907706 1.581 ENSMUST00000025057.4
Taf11
TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr6_-_83033422 1.580 ENSMUST00000089651.5
Dok1
docking protein 1
chr11_+_69965396 1.579 ENSMUST00000018713.6
Cldn7
claudin 7
chr1_+_59482133 1.572 ENSMUST00000114246.2
ENSMUST00000037105.6
Fzd7

frizzled homolog 7 (Drosophila)

chr11_+_110968056 1.569 ENSMUST00000125692.1
Kcnj16
potassium inwardly-rectifying channel, subfamily J, member 16
chr17_-_10840285 1.554 ENSMUST00000041463.6
Pacrg
PARK2 co-regulated
chr14_-_55681776 1.547 ENSMUST00000007733.6
Tinf2
Terf1 (TRF1)-interacting nuclear factor 2
chr11_-_84525514 1.541 ENSMUST00000018842.7
Lhx1
LIM homeobox protein 1
chr17_+_35979851 1.537 ENSMUST00000087200.3
Gnl1
guanine nucleotide binding protein-like 1
chr16_+_38562806 1.534 ENSMUST00000171687.1
ENSMUST00000002924.8
Tmem39a

transmembrane protein 39a

chr17_+_53479212 1.524 ENSMUST00000017975.5
Rab5a
RAB5A, member RAS oncogene family
chr13_-_64274879 1.518 ENSMUST00000109770.1
Cdc14b
CDC14 cell division cycle 14B
chr11_+_100320596 1.515 ENSMUST00000152521.1
Eif1
eukaryotic translation initiation factor 1
chr19_+_6057925 1.515 ENSMUST00000179142.1
Fau
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.4 26.1 GO:0046490 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
2.6 7.7 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931) calcium-independent cell-matrix adhesion(GO:0007161) transforming growth factor-beta secretion(GO:0038044)
2.4 14.6 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
2.3 9.2 GO:0045903 positive regulation of translational fidelity(GO:0045903)
2.3 13.5 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
2.0 2.0 GO:1903722 regulation of centriole elongation(GO:1903722)
1.8 5.5 GO:0014028 notochord formation(GO:0014028)
1.8 10.6 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
1.7 8.5 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
1.7 8.3 GO:0021905 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
1.6 4.9 GO:0051316 attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation(GO:0051316)
1.6 19.7 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
1.6 11.4 GO:0098535 positive regulation of centriole replication(GO:0046601) de novo centriole assembly(GO:0098535)
1.4 8.5 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
1.4 4.1 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
1.3 6.6 GO:0060591 chondroblast differentiation(GO:0060591)
1.3 3.9 GO:2000373 regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
1.2 14.9 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
1.2 3.6 GO:0006553 lysine metabolic process(GO:0006553)
1.1 5.7 GO:0010668 ectodermal cell differentiation(GO:0010668)
1.1 3.3 GO:0006083 acetate metabolic process(GO:0006083)
1.0 6.0 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.9 3.8 GO:1902990 leading strand elongation(GO:0006272) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.9 3.6 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.9 2.6 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.8 5.9 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.8 2.5 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.8 3.3 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986) general adaptation syndrome(GO:0051866)
0.8 1.5 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.8 6.9 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.8 3.1 GO:0060578 extraocular skeletal muscle development(GO:0002074) subthalamic nucleus development(GO:0021763) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.8 14.5 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.8 3.0 GO:2000319 negative regulation of T-helper 17 type immune response(GO:2000317) regulation of T-helper 17 cell differentiation(GO:2000319) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.8 3.8 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.7 2.2 GO:0035973 aggrephagy(GO:0035973)
0.7 4.8 GO:0006621 protein retention in ER lumen(GO:0006621)
0.7 7.4 GO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901030)
0.7 7.9 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.6 1.2 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.6 1.8 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.6 5.9 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.6 3.5 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.6 4.6 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.5 1.1 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.5 5.9 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.5 1.6 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.5 3.6 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.5 2.6 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.5 14.5 GO:0034508 centromere complex assembly(GO:0034508)
0.5 3.5 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.5 2.0 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.5 2.4 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.5 3.9 GO:0061084 negative regulation of protein refolding(GO:0061084)
0.5 10.3 GO:0044458 motile cilium assembly(GO:0044458)
0.5 1.8 GO:0051309 female meiosis chromosome separation(GO:0051309)
0.4 3.9 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.4 8.8 GO:0007530 sex determination(GO:0007530)
0.4 2.0 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.4 2.8 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.4 4.3 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.4 1.5 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.4 2.7 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.4 1.1 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.4 1.4 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.3 1.0 GO:1902162 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162)
0.3 1.0 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.3 1.7 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.3 1.0 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.3 2.3 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.3 1.0 GO:0051030 snRNA transport(GO:0051030)
0.3 5.4 GO:0072520 seminiferous tubule development(GO:0072520)
0.3 1.5 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.3 3.8 GO:0031639 plasminogen activation(GO:0031639)
0.3 0.9 GO:0009106 lipoate metabolic process(GO:0009106)
0.3 0.8 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.3 1.1 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.3 0.8 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.3 0.8 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.3 2.9 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.3 1.0 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.3 9.4 GO:0016572 histone phosphorylation(GO:0016572)
0.3 0.8 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
0.3 2.5 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.3 3.0 GO:0002227 innate immune response in mucosa(GO:0002227)
0.2 1.2 GO:0048539 bone marrow development(GO:0048539)
0.2 0.2 GO:0021593 rhombomere morphogenesis(GO:0021593)
0.2 2.9 GO:0019985 translesion synthesis(GO:0019985)
0.2 2.9 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2 1.3 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.2 1.3 GO:0072697 protein localization to cell cortex(GO:0072697)
0.2 1.5 GO:0051036 regulation of endosome size(GO:0051036)
0.2 2.1 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.2 1.1 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.2 3.1 GO:0042407 cristae formation(GO:0042407)
0.2 1.2 GO:0070365 hepatocyte differentiation(GO:0070365)
0.2 0.8 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.2 3.2 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.2 1.0 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.2 1.2 GO:0044375 regulation of peroxisome size(GO:0044375)
0.2 1.9 GO:0030049 muscle filament sliding(GO:0030049)
0.2 0.9 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.2 6.7 GO:0009409 response to cold(GO:0009409)
0.2 1.4 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.2 2.5 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.2 0.7 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.2 6.5 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.2 1.1 GO:0016584 nucleosome positioning(GO:0016584)
0.2 3.0 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 4.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 0.9 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.1 5.1 GO:0001709 cell fate determination(GO:0001709)
0.1 1.0 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 2.5 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.7 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 0.8 GO:0048254 snoRNA localization(GO:0048254)
0.1 0.9 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 2.8 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.1 2.1 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.1 0.4 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
0.1 2.8 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.1 3.1 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 0.7 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 0.5 GO:0090467 L-arginine import(GO:0043091) arginine import(GO:0090467)
0.1 1.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.3 GO:0030070 insulin processing(GO:0030070)
0.1 2.0 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 1.2 GO:1990403 embryonic brain development(GO:1990403)
0.1 0.2 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.1 0.5 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.6 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.1 0.6 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.1 0.4 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.3 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.1 1.4 GO:0043278 response to morphine(GO:0043278)
0.1 1.5 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.1 0.6 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 3.9 GO:0035082 axoneme assembly(GO:0035082)
0.1 0.5 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.1 1.6 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.1 3.2 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 0.7 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.3 GO:0009597 detection of virus(GO:0009597)
0.1 2.5 GO:0006270 DNA replication initiation(GO:0006270)
0.1 7.3 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.1 2.2 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.1 0.2 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.1 3.6 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 0.9 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 1.8 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.1 1.3 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 1.1 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.1 1.0 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.4 GO:0060699 regulation of endoribonuclease activity(GO:0060699) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702)
0.1 1.7 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.1 0.7 GO:0009048 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.1 0.3 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 0.9 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.1 6.8 GO:0006342 chromatin silencing(GO:0006342)
0.1 1.3 GO:0031670 cellular response to nutrient(GO:0031670)
0.1 0.2 GO:1903232 melanosome assembly(GO:1903232)
0.1 2.5 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.1 0.7 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 3.2 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.1 1.8 GO:0031648 protein destabilization(GO:0031648)
0.1 1.3 GO:0006379 mRNA cleavage(GO:0006379)
0.1 0.4 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.1 0.4 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 2.1 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.0 0.7 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.5 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.5 GO:0071028 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 0.2 GO:1904672 regulation of somatic stem cell population maintenance(GO:1904672)
0.0 0.3 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 3.1 GO:0051225 spindle assembly(GO:0051225)
0.0 0.3 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 2.6 GO:0071774 response to fibroblast growth factor(GO:0071774)
0.0 1.2 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.5 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.2 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 0.6 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988)
0.0 0.3 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 5.0 GO:0042254 ribosome biogenesis(GO:0042254)
0.0 1.7 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.4 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 0.3 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 10.2 GO:0008380 RNA splicing(GO:0008380)
0.0 3.6 GO:0048864 stem cell development(GO:0048864)
0.0 0.5 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.2 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 1.0 GO:0006352 DNA-templated transcription, initiation(GO:0006352)
0.0 8.7 GO:0006412 translation(GO:0006412)
0.0 0.6 GO:0048745 smooth muscle tissue development(GO:0048745)
0.0 3.1 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 4.5 GO:0007015 actin filament organization(GO:0007015)
0.0 0.2 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.3 GO:0042775 mitochondrial ATP synthesis coupled electron transport(GO:0042775)
0.0 0.3 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 0.4 GO:0017145 stem cell division(GO:0017145)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 9.1 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
2.6 7.7 GO:0005577 fibrinogen complex(GO:0005577)
2.1 14.9 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
2.0 8.0 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
1.9 11.4 GO:0098536 deuterosome(GO:0098536)
1.4 10.0 GO:0001940 male pronucleus(GO:0001940)
1.3 3.9 GO:0000799 nuclear condensin complex(GO:0000799)
1.3 3.8 GO:0070557 PCNA-p21 complex(GO:0070557)
1.2 12.0 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
1.0 10.6 GO:0005642 annulate lamellae(GO:0005642)
0.9 14.6 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.8 5.4 GO:0005828 kinetochore microtubule(GO:0005828)
0.7 2.2 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.7 11.6 GO:0030008 TRAPP complex(GO:0030008)
0.7 5.0 GO:0010009 cytoplasmic side of endosome membrane(GO:0010009)
0.7 11.8 GO:0031045 dense core granule(GO:0031045)
0.5 7.2 GO:0016589 NURF complex(GO:0016589)
0.5 20.4 GO:0097546 ciliary base(GO:0097546)
0.5 3.9 GO:0001520 outer dense fiber(GO:0001520)
0.4 14.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.4 3.0 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.4 1.7 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.4 22.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.4 2.9 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.4 2.0 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.4 2.0 GO:0030689 Noc complex(GO:0030689)
0.4 2.0 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.3 2.7 GO:0070652 HAUS complex(GO:0070652)
0.3 2.5 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.3 3.0 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.3 1.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.3 2.6 GO:0089701 U2AF(GO:0089701)
0.3 1.8 GO:0000796 condensin complex(GO:0000796)
0.3 2.3 GO:0061617 MICOS complex(GO:0061617)
0.2 1.5 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.2 3.0 GO:0030126 COPI vesicle coat(GO:0030126)
0.2 6.3 GO:0071011 precatalytic spliceosome(GO:0071011)
0.2 15.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 3.2 GO:0031011 Ino80 complex(GO:0031011)
0.2 1.2 GO:0000125 PCAF complex(GO:0000125)
0.2 2.0 GO:0000815 ESCRT III complex(GO:0000815)
0.2 0.8 GO:0005745 m-AAA complex(GO:0005745)
0.2 1.0 GO:1990246 uniplex complex(GO:1990246)
0.2 4.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.2 5.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.2 2.3 GO:0071437 invadopodium(GO:0071437)
0.2 2.7 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.2 2.0 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.2 1.9 GO:0016461 unconventional myosin complex(GO:0016461)
0.2 21.9 GO:0000776 kinetochore(GO:0000776)
0.1 0.8 GO:0070531 BRCA1-A complex(GO:0070531)
0.1 1.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 26.0 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 2.0 GO:0042555 MCM complex(GO:0042555)
0.1 7.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 1.9 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 1.7 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.9 GO:0033503 HULC complex(GO:0033503)
0.1 0.8 GO:0005638 lamin filament(GO:0005638)
0.1 1.9 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 1.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 2.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 6.9 GO:0015934 large ribosomal subunit(GO:0015934)
0.1 2.8 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.1 1.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 1.7 GO:0031528 microvillus membrane(GO:0031528)
0.1 4.3 GO:0044815 DNA packaging complex(GO:0044815)
0.1 4.3 GO:0005876 spindle microtubule(GO:0005876)
0.1 9.1 GO:0036126 sperm flagellum(GO:0036126)
0.1 6.6 GO:0005844 polysome(GO:0005844)
0.1 1.3 GO:0044292 dendrite terminus(GO:0044292)
0.1 1.5 GO:0010369 chromocenter(GO:0010369)
0.1 1.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 0.5 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.9 GO:0001739 sex chromatin(GO:0001739)
0.1 4.1 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 2.5 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 4.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 1.2 GO:0000800 lateral element(GO:0000800)
0.1 0.4 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) Holliday junction resolvase complex(GO:0048476)
0.1 1.4 GO:0032587 ruffle membrane(GO:0032587)
0.1 0.2 GO:0042827 platelet dense granule(GO:0042827)
0.1 2.8 GO:0031514 motile cilium(GO:0031514)
0.1 0.3 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 0.3 GO:0034709 methylosome(GO:0034709)
0.1 0.8 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 2.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.7 GO:0030686 90S preribosome(GO:0030686)
0.0 14.0 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 2.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.6 GO:0016592 mediator complex(GO:0016592)
0.0 1.2 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 1.3 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 9.8 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.3 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 2.6 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.4 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.8 GO:0005840 ribosome(GO:0005840)
0.0 0.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.9 GO:0014704 intercalated disc(GO:0014704)
0.0 0.6 GO:0051233 spindle midzone(GO:0051233)
0.0 0.7 GO:0030286 dynein complex(GO:0030286)
0.0 0.4 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.4 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 3.5 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.5 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 4.6 GO:0016607 nuclear speck(GO:0016607)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 4.7 GO:0016604 nuclear body(GO:0016604)
0.0 0.5 GO:0032420 stereocilium(GO:0032420)
0.0 0.6 GO:0031902 late endosome membrane(GO:0031902)
0.0 1.8 GO:0005923 bicellular tight junction(GO:0005923)
0.0 1.5 GO:0001650 fibrillar center(GO:0001650)
0.0 1.5 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.0 GO:0036064 ciliary basal body(GO:0036064)
0.0 1.1 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.4 GO:0031519 PcG protein complex(GO:0031519)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.5 13.5 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
1.8 9.0 GO:0032027 myosin light chain binding(GO:0032027)
1.7 8.3 GO:0043515 kinetochore binding(GO:0043515)
1.5 9.2 GO:1990932 5.8S rRNA binding(GO:1990932)
1.3 5.2 GO:0046923 ER retention sequence binding(GO:0046923)
1.3 7.7 GO:0045340 mercury ion binding(GO:0045340)
1.3 3.8 GO:0032139 DNA polymerase processivity factor activity(GO:0030337) dinucleotide insertion or deletion binding(GO:0032139)
1.1 9.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
1.1 3.3 GO:0003987 acetate-CoA ligase activity(GO:0003987)
1.1 13.9 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
1.0 14.6 GO:0001054 RNA polymerase I activity(GO:0001054)
1.0 3.9 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.9 3.8 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.9 6.8 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.8 2.5 GO:0070052 collagen V binding(GO:0070052)
0.8 2.5 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.8 7.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.8 3.0 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.7 2.2 GO:0019776 Atg8 ligase activity(GO:0019776)
0.7 8.7 GO:0001618 virus receptor activity(GO:0001618)
0.7 10.6 GO:0017070 U6 snRNA binding(GO:0017070)
0.7 2.0 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.6 14.9 GO:0017160 Ral GTPase binding(GO:0017160)
0.6 3.8 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.6 3.8 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.5 8.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.5 8.3 GO:0003680 AT DNA binding(GO:0003680)
0.4 3.9 GO:0032564 dATP binding(GO:0032564)
0.4 2.0 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.4 3.1 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.4 3.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.4 2.6 GO:0050733 RS domain binding(GO:0050733)
0.3 1.0 GO:0071633 dihydroceramidase activity(GO:0071633)
0.3 2.7 GO:0008420 CTD phosphatase activity(GO:0008420)
0.3 6.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.3 1.2 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.3 1.2 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.3 14.1 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.3 6.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.3 0.8 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.3 2.9 GO:0031996 thioesterase binding(GO:0031996)
0.3 1.5 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)
0.3 2.5 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.3 2.8 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.2 0.5 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.2 0.7 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.2 1.4 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.2 0.9 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.2 1.2 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.2 7.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 7.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.2 0.8 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.2 9.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2 1.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.2 0.6 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.2 0.6 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.2 0.7 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.2 2.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 1.1 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.2 29.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 0.9 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.2 0.7 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.2 0.7 GO:0097108 hedgehog family protein binding(GO:0097108)
0.2 8.9 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.2 3.6 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.2 3.5 GO:0000400 four-way junction DNA binding(GO:0000400)
0.2 5.1 GO:0017147 Wnt-protein binding(GO:0017147)
0.2 3.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.2 2.6 GO:0045504 dynein heavy chain binding(GO:0045504)
0.2 2.1 GO:0043495 protein anchor(GO:0043495)
0.1 2.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 1.9 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 1.2 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 1.0 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 1.9 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 3.9 GO:0005109 frizzled binding(GO:0005109)
0.1 1.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 7.0 GO:0005179 hormone activity(GO:0005179)
0.1 0.3 GO:0030519 snoRNP binding(GO:0030519)
0.1 1.0 GO:0015643 toxic substance binding(GO:0015643)
0.1 1.6 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 0.3 GO:0043426 MRF binding(GO:0043426)
0.1 0.8 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.1 2.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.4 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.5 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.5 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.6 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 3.7 GO:0020037 heme binding(GO:0020037)
0.1 1.4 GO:0043422 protein kinase B binding(GO:0043422)
0.1 0.5 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 2.5 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.1 1.3 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 3.4 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 1.7 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 1.5 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 0.8 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 3.5 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 5.8 GO:0051082 unfolded protein binding(GO:0051082)
0.1 2.4 GO:0019843 rRNA binding(GO:0019843)
0.1 2.8 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.1 1.6 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.1 0.4 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 3.6 GO:0004497 monooxygenase activity(GO:0004497)
0.1 1.4 GO:0048156 tau protein binding(GO:0048156)
0.1 4.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 12.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 4.7 GO:0031491 nucleosome binding(GO:0031491)
0.1 0.7 GO:0005522 profilin binding(GO:0005522)
0.1 1.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 1.2 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 1.8 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 1.5 GO:0030515 snoRNA binding(GO:0030515)
0.1 3.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 1.0 GO:0070717 poly-purine tract binding(GO:0070717)
0.1 0.6 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.1 0.4 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.2 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.3 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.8 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.9 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 1.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 4.3 GO:0008013 beta-catenin binding(GO:0008013)
0.0 7.7 GO:0042393 histone binding(GO:0042393)
0.0 3.3 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 1.3 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.8 GO:0030332 cyclin binding(GO:0030332)
0.0 4.1 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 1.9 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 1.2 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.3 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 1.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.8 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 1.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.3 GO:0004707 MAP kinase activity(GO:0004707)
0.0 1.1 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.2 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.7 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 1.4 GO:0002020 protease binding(GO:0002020)
0.0 0.6 GO:0019003 GDP binding(GO:0019003)
0.0 0.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.4 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.6 GO:0032934 cholesterol binding(GO:0015485) sterol binding(GO:0032934)
0.0 0.7 GO:0051087 chaperone binding(GO:0051087)
0.0 0.4 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.4 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 15.9 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.8 14.3 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.3 3.1 ST_TYPE_I_INTERFERON_PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.3 15.4 PID_AURORA_B_PATHWAY Aurora B signaling
0.3 8.5 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.3 10.7 PID_BARD1_PATHWAY BARD1 signaling events
0.2 5.5 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.2 5.1 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.1 5.8 PID_PLK1_PATHWAY PLK1 signaling events
0.1 2.5 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.1 7.8 PID_P53_REGULATION_PATHWAY p53 pathway
0.1 3.1 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 3.6 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 1.2 PID_MYC_PATHWAY C-MYC pathway
0.1 0.9 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.1 2.8 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.1 2.8 PID_HIV_NEF_PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1 3.1 PID_E2F_PATHWAY E2F transcription factor network
0.1 1.3 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.1 1.5 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.1 4.5 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.1 2.1 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 0.6 PID_FOXO_PATHWAY FoxO family signaling
0.0 3.4 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.3 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.7 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.9 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.6 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 3.0 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.6 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.8 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 1.3 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.2 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.5 PID_TELOMERASE_PATHWAY Regulation of Telomerase

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 13.5 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
1.1 26.4 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.9 14.9 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.8 3.3 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.6 8.3 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.6 10.0 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.5 7.7 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.5 18.3 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.4 10.8 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.4 22.7 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.4 10.6 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.4 10.8 REACTOME_KINESINS Genes involved in Kinesins
0.4 3.5 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.4 3.8 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.3 3.0 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.2 15.7 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.2 6.9 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.2 14.1 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.2 1.7 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.2 2.0 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.2 2.5 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.2 11.1 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 3.8 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 2.5 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 1.5 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 4.2 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.1 6.1 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 2.0 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.1 1.7 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 2.6 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.1 7.8 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.1 2.9 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.1 8.3 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 3.6 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.6 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.1 3.8 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.1 2.7 REACTOME_G1_PHASE Genes involved in G1 Phase
0.1 4.6 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 10.1 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.1 1.4 REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR Genes involved in Signaling by constitutively active EGFR
0.1 1.1 REACTOME_3_UTR_MEDIATED_TRANSLATIONAL_REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.1 0.9 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 0.5 REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 2.0 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.1 REACTOME_PHOSPHORYLATION_OF_THE_APC_C Genes involved in Phosphorylation of the APC/C
0.1 2.2 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 1.3 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.1 1.4 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 0.7 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.8 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 2.0 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.8 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.4 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 3.2 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.6 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.8 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.3 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.7 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.8 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.5 REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.8 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.9 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 3.5 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.5 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.6 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.2 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.4 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation