Motif ID: Cebpd

Z-value: 0.407


Transcription factors associated with Cebpd:

Gene SymbolEntrez IDGene Name
Cebpd ENSMUSG00000071637.4 Cebpd



Activity profile for motif Cebpd.

activity profile for motif Cebpd


Sorted Z-values histogram for motif Cebpd

Sorted Z-values for motif Cebpd



Network of associatons between targets according to the STRING database.



First level regulatory network of Cebpd

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_-_52529847 1.052 ENSMUST00000171470.1
Lox
lysyl oxidase
chr9_-_103230415 1.037 ENSMUST00000035158.9
Trf
transferrin
chr11_-_75422586 0.988 ENSMUST00000138661.1
ENSMUST00000000769.7
Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr18_-_52529692 0.948 ENSMUST00000025409.7
Lox
lysyl oxidase
chr1_-_140183404 0.904 ENSMUST00000066859.6
ENSMUST00000111976.2
Cfh

complement component factor h

chr2_+_25180737 0.887 ENSMUST00000104999.2
Nrarp
Notch-regulated ankyrin repeat protein
chr6_+_17463749 0.853 ENSMUST00000115443.1
Met
met proto-oncogene
chr11_-_77894096 0.737 ENSMUST00000017597.4
Pipox
pipecolic acid oxidase
chr11_-_48826500 0.704 ENSMUST00000161192.2
Gm12184
predicted gene 12184
chr11_-_48826655 0.701 ENSMUST00000104959.1
Gm12184
predicted gene 12184
chr8_-_33929798 0.671 ENSMUST00000033995.7
ENSMUST00000033994.8
ENSMUST00000053251.5
Rbpms


RNA binding protein gene with multiple splicing


chr5_+_63812447 0.667 ENSMUST00000081747.3
0610040J01Rik
RIKEN cDNA 0610040J01 gene
chr11_-_75422524 0.640 ENSMUST00000125982.1
ENSMUST00000137103.1
Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr1_-_140183283 0.634 ENSMUST00000111977.1
Cfh
complement component factor h
chr9_-_103230262 0.587 ENSMUST00000165296.1
ENSMUST00000112645.1
ENSMUST00000166836.1
Trf

Gm20425
transferrin

predicted gene 20425
chr17_+_86963077 0.562 ENSMUST00000024956.8
Rhoq
ras homolog gene family, member Q
chr2_+_155751117 0.510 ENSMUST00000029140.5
ENSMUST00000132608.1
Procr

protein C receptor, endothelial

chr4_-_108833608 0.459 ENSMUST00000102742.4
Btf3l4
basic transcription factor 3-like 4
chr13_+_63015167 0.419 ENSMUST00000021911.8
2010111I01Rik
RIKEN cDNA 2010111I01 gene
chr3_+_66219909 0.395 ENSMUST00000029421.5
Ptx3
pentraxin related gene
chrX_-_134600976 0.375 ENSMUST00000033621.6
Gla
galactosidase, alpha
chr14_-_18893376 0.365 ENSMUST00000151926.1
Ube2e2
ubiquitin-conjugating enzyme E2E 2
chr3_+_19957037 0.364 ENSMUST00000091309.5
ENSMUST00000108329.1
ENSMUST00000003714.6
Cp


ceruloplasmin


chr17_+_48346401 0.339 ENSMUST00000024791.8
Trem2
triggering receptor expressed on myeloid cells 2
chr11_-_87086752 0.322 ENSMUST00000020801.7
Smg8
smg-8 homolog, nonsense mediated mRNA decay factor (C. elegans)
chr4_-_130359915 0.301 ENSMUST00000134159.2
Zcchc17
zinc finger, CCHC domain containing 17
chr4_-_108833544 0.293 ENSMUST00000102740.1
ENSMUST00000102741.1
Btf3l4

basic transcription factor 3-like 4

chr13_+_63014934 0.287 ENSMUST00000091560.4
2010111I01Rik
RIKEN cDNA 2010111I01 gene
chr17_+_48346465 0.276 ENSMUST00000113237.3
Trem2
triggering receptor expressed on myeloid cells 2
chr17_-_56121946 0.251 ENSMUST00000041357.7
Lrg1
leucine-rich alpha-2-glycoprotein 1
chrX_+_7763943 0.238 ENSMUST00000144900.1
ENSMUST00000115677.1
ENSMUST00000101695.2
ENSMUST00000115678.2
Tfe3



transcription factor E3



chr17_+_86963279 0.227 ENSMUST00000139344.1
Rhoq
ras homolog gene family, member Q
chr1_-_71653162 0.220 ENSMUST00000055226.6
Fn1
fibronectin 1
chr7_-_127273919 0.215 ENSMUST00000082428.3
Sephs2
selenophosphate synthetase 2
chr7_+_30751471 0.208 ENSMUST00000182229.1
ENSMUST00000182227.1
ENSMUST00000080518.6
ENSMUST00000182721.1
Sbsn



suprabasin



chr11_-_78080360 0.197 ENSMUST00000021183.3
Eral1
Era (G-protein)-like 1 (E. coli)
chr11_+_62077018 0.187 ENSMUST00000092415.5
Specc1
sperm antigen with calponin homology and coiled-coil domains 1
chr7_-_45830776 0.183 ENSMUST00000107723.2
ENSMUST00000131384.1
Grwd1

glutamate-rich WD repeat containing 1

chr12_+_86421628 0.182 ENSMUST00000110203.1
ENSMUST00000110204.2
Esrrb

estrogen related receptor, beta

chr5_+_115279666 0.167 ENSMUST00000040421.4
Coq5
coenzyme Q5 homolog, methyltransferase (yeast)
chr14_-_18893623 0.165 ENSMUST00000177259.1
Ube2e2
ubiquitin-conjugating enzyme E2E 2
chr11_+_6415443 0.154 ENSMUST00000132846.1
Ppia
peptidylprolyl isomerase A
chr5_-_147894804 0.130 ENSMUST00000118527.1
ENSMUST00000031655.3
ENSMUST00000138244.1
Slc46a3


solute carrier family 46, member 3


chr5_+_145140362 0.130 ENSMUST00000162594.1
ENSMUST00000162308.1
ENSMUST00000159018.1
ENSMUST00000160075.1
Bud31



BUD31 homolog (yeast)



chr4_+_152039315 0.129 ENSMUST00000084116.6
ENSMUST00000105663.1
ENSMUST00000103197.3
Nol9


nucleolar protein 9


chr5_-_145140238 0.109 ENSMUST00000031627.8
Pdap1
PDGFA associated protein 1
chr18_+_20944607 0.107 ENSMUST00000050004.1
Rnf125
ring finger protein 125
chr2_-_129371131 0.106 ENSMUST00000028881.7
Il1b
interleukin 1 beta
chr12_+_24572276 0.075 ENSMUST00000085553.5
Grhl1
grainyhead-like 1 (Drosophila)
chr14_-_45477856 0.074 ENSMUST00000141424.1
Fermt2
fermitin family homolog 2 (Drosophila)
chr1_-_162898665 0.072 ENSMUST00000111510.1
ENSMUST00000045902.6
Fmo2

flavin containing monooxygenase 2

chr1_+_136131382 0.072 ENSMUST00000075164.4
Kif21b
kinesin family member 21B
chrX_+_134601179 0.051 ENSMUST00000074950.4
ENSMUST00000113203.1
ENSMUST00000113202.1
Hnrnph2


heterogeneous nuclear ribonucleoprotein H2


chrX_+_134601271 0.037 ENSMUST00000050331.6
ENSMUST00000059297.5
Hnrnph2

heterogeneous nuclear ribonucleoprotein H2

chr19_-_8819314 0.029 ENSMUST00000096751.4
Ttc9c
tetratricopeptide repeat domain 9C
chr12_-_84194007 0.019 ENSMUST00000110294.1
Elmsan1
ELM2 and Myb/SANT-like domain containing 1
chr12_+_37241633 0.007 ENSMUST00000049874.7
Agmo
alkylglycerol monooxygenase
chr1_+_178405881 0.006 ENSMUST00000027775.7
Efcab2
EF-hand calcium binding domain 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 GO:0045919 complement activation, alternative pathway(GO:0006957) positive regulation of cytolysis(GO:0045919)
0.2 0.7 GO:0006553 lysine metabolic process(GO:0006553)
0.2 2.0 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 0.6 GO:0002586 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588) detection of peptidoglycan(GO:0032499)
0.2 1.6 GO:0098707 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.2 1.6 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1 0.9 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.1 0.9 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 0.4 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.1 0.2 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931) calcium-independent cell-matrix adhesion(GO:0007161) transforming growth factor-beta secretion(GO:0038044)
0.1 0.5 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.2 GO:0001887 selenium compound metabolic process(GO:0001887) selenocysteine metabolic process(GO:0016259)
0.0 0.4 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.2 GO:0090282 positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931) positive regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0090282)
0.0 0.1 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.0 0.1 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092) positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.0 0.7 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.8 GO:1903077 negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.7 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.4 GO:0046688 response to copper ion(GO:0046688)
0.0 0.1 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 0.5 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 0.1 GO:0002934 desmosome organization(GO:0002934)
0.0 0.2 GO:0006337 nucleosome disassembly(GO:0006337)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 GO:0097433 dense body(GO:0097433)
0.1 1.6 GO:0043203 axon hillock(GO:0043203)
0.1 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 2.0 GO:0005581 collagen trimer(GO:0005581)
0.0 0.7 GO:0005685 U1 snRNP(GO:0005685)
0.0 1.8 GO:0072562 blood microparticle(GO:0072562)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.7 GO:0009925 basal plasma membrane(GO:0009925)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.4 1.5 GO:0001851 complement component C3b binding(GO:0001851)
0.2 1.6 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.2 0.9 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.2 0.7 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.2 0.6 GO:0070891 peptidoglycan binding(GO:0042834) lipoteichoic acid binding(GO:0070891)
0.1 0.7 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.5 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 0.4 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.4 GO:0016936 galactoside binding(GO:0016936)
0.1 0.8 GO:0005522 profilin binding(GO:0005522)
0.1 0.4 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.2 GO:0045340 mercury ion binding(GO:0045340)
0.0 1.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.6 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.8 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 0.9 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.2 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.4 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.1 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.0 0.6 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.9 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.2 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.4 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.4 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism