Motif ID: Emx1_Emx2

Z-value: 0.587

Transcription factors associated with Emx1_Emx2:

Gene SymbolEntrez IDGene Name
Emx1 ENSMUSG00000033726.8 Emx1
Emx2 ENSMUSG00000043969.4 Emx2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Emx2mm10_v2_chr19_+_59458372_59458450-0.305.3e-02Click!
Emx1mm10_v2_chr6_+_85187438_85187510-0.153.4e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Emx1_Emx2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_118961578 4.017 ENSMUST00000058651.4
Lao1
L-amino acid oxidase 1
chr7_-_103827922 3.187 ENSMUST00000023934.6
ENSMUST00000153218.1
Hbb-bs

hemoglobin, beta adult s chain

chr4_-_82505749 3.008 ENSMUST00000107245.2
ENSMUST00000107246.1
Nfib

nuclear factor I/B

chr4_-_82505274 2.672 ENSMUST00000050872.8
ENSMUST00000064770.2
Nfib

nuclear factor I/B

chr17_-_36032682 2.324 ENSMUST00000102678.4
H2-T23
histocompatibility 2, T region locus 23
chr4_-_82505707 2.107 ENSMUST00000107248.1
ENSMUST00000107247.1
Nfib

nuclear factor I/B

chr10_+_81257277 2.067 ENSMUST00000117488.1
ENSMUST00000105328.3
ENSMUST00000121205.1
Matk


megakaryocyte-associated tyrosine kinase


chr10_+_90071095 1.822 ENSMUST00000183109.1
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr7_-_142661858 1.652 ENSMUST00000145896.2
Igf2
insulin-like growth factor 2
chr16_-_26371828 1.622 ENSMUST00000023154.2
Cldn1
claudin 1
chr8_-_21906412 1.466 ENSMUST00000051965.4
Defb11
defensin beta 11
chr7_+_126781483 1.407 ENSMUST00000172352.1
ENSMUST00000094037.4
Tbx6

T-box 6

chr2_-_160619971 1.339 ENSMUST00000109473.1
Gm14221
predicted gene 14221
chrX_+_8271133 1.271 ENSMUST00000127103.1
ENSMUST00000115591.1
Slc38a5

solute carrier family 38, member 5

chr13_-_97747373 1.242 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr3_+_121953213 1.146 ENSMUST00000037958.7
ENSMUST00000128366.1
Arhgap29

Rho GTPase activating protein 29

chr11_+_109543694 1.055 ENSMUST00000106696.1
Arsg
arylsulfatase G
chr3_+_137341103 1.008 ENSMUST00000119475.1
Emcn
endomucin
chr13_-_97747399 0.968 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr1_-_158356258 0.926 ENSMUST00000004133.8
Brinp2
bone morphogenic protein/retinoic acid inducible neural-specific 2
chr5_-_28210022 0.865 ENSMUST00000118882.1
Cnpy1
canopy 1 homolog (zebrafish)
chr3_-_49757257 0.838 ENSMUST00000035931.7
Pcdh18
protocadherin 18
chr2_+_36230426 0.818 ENSMUST00000062069.5
Ptgs1
prostaglandin-endoperoxide synthase 1
chr6_-_57535422 0.810 ENSMUST00000042766.3
Ppm1k
protein phosphatase 1K (PP2C domain containing)
chr8_+_69300776 0.798 ENSMUST00000078257.6
D130040H23Rik
RIKEN cDNA D130040H23 gene
chr12_+_36314160 0.769 ENSMUST00000041407.5
Sostdc1
sclerostin domain containing 1
chr12_-_90969768 0.768 ENSMUST00000181184.1
4930544I03Rik
RIKEN cDNA 4930544I03 gene
chr18_-_15403680 0.761 ENSMUST00000079081.6
Aqp4
aquaporin 4
chr3_+_90541146 0.713 ENSMUST00000107333.1
ENSMUST00000107331.1
ENSMUST00000098910.2
S100a16


S100 calcium binding protein A16


chr3_+_137341067 0.692 ENSMUST00000122064.1
Emcn
endomucin
chr14_-_57133585 0.661 ENSMUST00000039380.8
Gjb6
gap junction protein, beta 6
chr9_+_72958785 0.656 ENSMUST00000098567.2
ENSMUST00000034734.8
Dyx1c1

dyslexia susceptibility 1 candidate 1 homolog (human)

chr12_-_98577940 0.656 ENSMUST00000110113.1
Kcnk10
potassium channel, subfamily K, member 10
chr2_+_175469985 0.635 ENSMUST00000109042.3
ENSMUST00000109002.2
ENSMUST00000109043.2
ENSMUST00000143490.1
Gm8923



predicted gene 8923



chr4_+_126609818 0.626 ENSMUST00000097886.3
ENSMUST00000164362.1
5730409E04Rik

RIKEN cDNA 5730409E04Rik gene

chr16_-_97170707 0.615 ENSMUST00000056102.7
Dscam
Down syndrome cell adhesion molecule
chr13_+_23763660 0.610 ENSMUST00000055770.1
Hist1h1a
histone cluster 1, H1a
chr2_-_175703646 0.590 ENSMUST00000109027.2
ENSMUST00000179061.1
ENSMUST00000131041.1
Gm4245


predicted gene 4245


chr2_+_175372436 0.589 ENSMUST00000131676.1
ENSMUST00000109048.2
ENSMUST00000109047.2
Gm4723


predicted gene 4723


chr13_+_16014457 0.585 ENSMUST00000164993.1
Inhba
inhibin beta-A
chr17_-_45599603 0.575 ENSMUST00000171847.1
ENSMUST00000166633.1
ENSMUST00000169729.1
Slc29a1


solute carrier family 29 (nucleoside transporters), member 1


chr10_-_53647080 0.566 ENSMUST00000169866.1
Fam184a
family with sequence similarity 184, member A
chr17_-_31636631 0.562 ENSMUST00000135425.1
ENSMUST00000151718.1
ENSMUST00000155814.1
Cbs


cystathionine beta-synthase


chr1_-_144177259 0.558 ENSMUST00000111941.1
ENSMUST00000052375.1
Rgs13

regulator of G-protein signaling 13

chr14_+_55560010 0.508 ENSMUST00000147981.1
ENSMUST00000133256.1
Dcaf11

DDB1 and CUL4 associated factor 11

chr18_-_73754457 0.475 ENSMUST00000041138.2
Elac1
elaC homolog 1 (E. coli)
chr8_+_34054622 0.457 ENSMUST00000149618.1
Gm9951
predicted gene 9951
chr17_+_45734506 0.439 ENSMUST00000180558.1
F630040K05Rik
RIKEN cDNA F630040K05 gene
chr4_-_150914401 0.431 ENSMUST00000105675.1
Park7
Parkinson disease (autosomal recessive, early onset) 7
chr10_-_25297055 0.421 ENSMUST00000177124.1
Akap7
A kinase (PRKA) anchor protein 7
chr9_-_124304718 0.417 ENSMUST00000071300.6
2010315B03Rik
RIKEN cDNA 2010315B03 gene
chr5_+_135009152 0.415 ENSMUST00000111216.1
ENSMUST00000046999.8
Abhd11

abhydrolase domain containing 11

chrM_+_11734 0.414 ENSMUST00000082418.1
mt-Nd5
mitochondrially encoded NADH dehydrogenase 5
chr6_-_129533267 0.413 ENSMUST00000181594.1
1700101I11Rik
RIKEN cDNA 1700101I11 gene
chr7_-_5413145 0.411 ENSMUST00000108569.2
Vmn1r58
vomeronasal 1 receptor 58
chr18_-_34579072 0.411 ENSMUST00000079287.5
Nme5
NME/NM23 family member 5
chr4_+_102589687 0.408 ENSMUST00000097949.4
ENSMUST00000106901.1
Pde4b

phosphodiesterase 4B, cAMP specific

chr9_+_56418624 0.391 ENSMUST00000034879.3
Hmg20a
high mobility group 20A
chr10_-_86011833 0.379 ENSMUST00000105304.1
ENSMUST00000061699.5
Bpifc

BPI fold containing family C

chr9_-_15301555 0.369 ENSMUST00000034414.8
4931406C07Rik
RIKEN cDNA 4931406C07 gene
chr14_-_18893376 0.360 ENSMUST00000151926.1
Ube2e2
ubiquitin-conjugating enzyme E2E 2
chr8_-_8690493 0.359 ENSMUST00000048545.8
Arglu1
arginine and glutamate rich 1
chr16_-_44016387 0.319 ENSMUST00000036174.3
Gramd1c
GRAM domain containing 1C
chr14_+_26259109 0.316 ENSMUST00000174494.1
Duxbl3
double homeobox B-like 3
chr12_-_56345862 0.315 ENSMUST00000021416.7
Mbip
MAP3K12 binding inhibitory protein 1
chr15_+_99295087 0.308 ENSMUST00000128352.1
ENSMUST00000145482.1
Prpf40b

PRP40 pre-mRNA processing factor 40 homolog B (yeast)

chr4_+_110397661 0.306 ENSMUST00000106589.2
ENSMUST00000106587.2
ENSMUST00000106591.1
ENSMUST00000106592.1
Agbl4



ATP/GTP binding protein-like 4



chr14_+_53324632 0.300 ENSMUST00000178100.1
Trav7n-6
T cell receptor alpha variable 7N-6
chr6_+_79818031 0.293 ENSMUST00000179797.1
Gm20594
predicted gene, 20594
chr6_+_17749170 0.292 ENSMUST00000053148.7
ENSMUST00000115417.3
St7

suppression of tumorigenicity 7

chrM_+_2743 0.289 ENSMUST00000082392.1
mt-Nd1
mitochondrially encoded NADH dehydrogenase 1
chr9_-_20728219 0.280 ENSMUST00000034692.7
Olfm2
olfactomedin 2
chr14_+_25979401 0.279 ENSMUST00000173580.1
Duxbl1
double homeobox B-like 1
chr14_+_25980039 0.278 ENSMUST00000173155.1
Duxbl1
double homeobox B-like 1
chr2_-_34826071 0.274 ENSMUST00000113077.1
ENSMUST00000028220.3
Fbxw2

F-box and WD-40 domain protein 2

chr4_+_110397764 0.273 ENSMUST00000097920.2
ENSMUST00000080744.6
Agbl4

ATP/GTP binding protein-like 4

chr1_-_40085823 0.270 ENSMUST00000181756.1
Gm16894
predicted gene, 16894
chr7_-_101845300 0.268 ENSMUST00000094141.5
Folr2
folate receptor 2 (fetal)
chrX_-_102505359 0.267 ENSMUST00000087916.4
Hdac8
histone deacetylase 8
chr10_+_79996479 0.266 ENSMUST00000132517.1
Abca7
ATP-binding cassette, sub-family A (ABC1), member 7
chr2_+_110597298 0.253 ENSMUST00000045972.6
ENSMUST00000111026.2
Slc5a12

solute carrier family 5 (sodium/glucose cotransporter), member 12

chr12_-_87388317 0.248 ENSMUST00000021424.4
Sptlc2
serine palmitoyltransferase, long chain base subunit 2
chr11_-_42000284 0.232 ENSMUST00000109292.2
ENSMUST00000109290.1
Gabrg2

gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2

chr3_-_130730375 0.232 ENSMUST00000079085.6
Rpl34
ribosomal protein L34
chr7_+_132610620 0.232 ENSMUST00000033241.5
Lhpp
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
chr3_-_146495115 0.230 ENSMUST00000093951.2
Spata1
spermatogenesis associated 1
chr13_-_106847267 0.227 ENSMUST00000057427.4
Lrrc70
leucine rich repeat containing 70
chr2_-_34826187 0.221 ENSMUST00000113075.1
ENSMUST00000113080.2
ENSMUST00000091020.3
Fbxw2


F-box and WD-40 domain protein 2


chr7_-_84679346 0.217 ENSMUST00000069537.2
ENSMUST00000178385.1
Zfand6

zinc finger, AN1-type domain 6

chr8_+_85432686 0.214 ENSMUST00000180883.1
1700051O22Rik
RIKEN cDNA 1700051O22 Gene
chr17_+_29274078 0.205 ENSMUST00000149405.2
BC004004
cDNA sequence BC004004
chr12_-_98259416 0.199 ENSMUST00000021390.7
Galc
galactosylceramidase
chrX_-_150814265 0.199 ENSMUST00000026302.6
ENSMUST00000129768.1
ENSMUST00000112699.2
Maged2


melanoma antigen, family D, 2


chr4_-_155645408 0.195 ENSMUST00000115821.2
Gm10563
predicted gene 10563
chr14_+_26119173 0.192 ENSMUST00000174564.1
Duxbl2
doubl homeobox B-like 2
chr14_+_26258786 0.192 ENSMUST00000172517.1
Duxbl3
double homeobox B-like 3
chr4_-_64276595 0.191 ENSMUST00000141162.1
Gm11217
predicted gene 11217
chr2_+_144594054 0.191 ENSMUST00000136628.1
Gm561
predicted gene 561
chr3_-_151749877 0.189 ENSMUST00000029671.7
Ifi44
interferon-induced protein 44
chr19_+_34217588 0.182 ENSMUST00000119603.1
Stambpl1
STAM binding protein like 1
chr1_+_63176818 0.179 ENSMUST00000129339.1
Eef1b2
eukaryotic translation elongation factor 1 beta 2
chr2_-_73580288 0.178 ENSMUST00000028515.3
Chrna1
cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
chr10_+_81183000 0.173 ENSMUST00000178422.1
Dapk3
death-associated protein kinase 3
chr8_+_72219726 0.170 ENSMUST00000003123.8
Fam32a
family with sequence similarity 32, member A
chr14_+_26119811 0.169 ENSMUST00000173617.1
Duxbl2
doubl homeobox B-like 2
chr17_+_14943184 0.165 ENSMUST00000052691.8
ENSMUST00000164837.2
ENSMUST00000174004.1
1600012H06Rik


RIKEN cDNA 1600012H06 gene


chr6_+_42245907 0.165 ENSMUST00000031897.5
Gstk1
glutathione S-transferase kappa 1
chrX_-_160994665 0.161 ENSMUST00000087104.4
Cdkl5
cyclin-dependent kinase-like 5
chrX_-_74393003 0.161 ENSMUST00000015427.6
Fam3a
family with sequence similarity 3, member A
chr3_+_88716838 0.161 ENSMUST00000029692.8
ENSMUST00000171645.1
Rit1

Ras-like without CAAX 1

chr7_-_97738222 0.160 ENSMUST00000084986.6
Aqp11
aquaporin 11
chr10_+_128322443 0.156 ENSMUST00000026446.2
Cnpy2
canopy 2 homolog (zebrafish)
chr6_+_124304646 0.155 ENSMUST00000112541.2
ENSMUST00000032234.2
Cd163

CD163 antigen

chr3_+_32436376 0.155 ENSMUST00000108242.1
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr6_-_101377342 0.150 ENSMUST00000151175.1
Pdzrn3
PDZ domain containing RING finger 3
chr14_+_118137101 0.149 ENSMUST00000022728.2
Gpr180
G protein-coupled receptor 180
chr17_-_32822200 0.138 ENSMUST00000179695.1
Zfp799
zinc finger protein 799
chr1_+_93685574 0.135 ENSMUST00000027499.6
Bok
BCL2-related ovarian killer protein
chr7_-_38019505 0.134 ENSMUST00000085513.4
Uri1
URI1, prefoldin-like chaperone
chr15_+_85510812 0.133 ENSMUST00000079690.2
Gm4825
predicted pseudogene 4825
chr4_+_147492417 0.133 ENSMUST00000105721.2
Gm13152
predicted gene 13152
chr12_-_12940600 0.132 ENSMUST00000130990.1
Mycn
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr3_+_121531603 0.132 ENSMUST00000180804.1
A530020G20Rik
RIKEN cDNA A530020G20 gene
chr2_-_119662756 0.130 ENSMUST00000028768.1
ENSMUST00000110801.1
ENSMUST00000110802.1
Ndufaf1


NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1


chr16_+_21794320 0.127 ENSMUST00000181780.1
ENSMUST00000181960.1
1300002E11Rik

RIKEN cDNA 1300002E11 gene

chr6_+_129533183 0.117 ENSMUST00000032264.6
Gabarapl1
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
chr14_-_15438974 0.116 ENSMUST00000055211.4
Lrrc3b
leucine rich repeat containing 3B
chr7_-_125491397 0.115 ENSMUST00000138616.1
Nsmce1
non-SMC element 1 homolog (S. cerevisiae)
chr2_-_67194695 0.114 ENSMUST00000147939.1
Gm13598
predicted gene 13598
chr3_+_32436151 0.110 ENSMUST00000029201.7
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr1_-_184999549 0.106 ENSMUST00000027929.4
Mark1
MAP/microtubule affinity-regulating kinase 1
chr13_-_4609122 0.105 ENSMUST00000110691.3
ENSMUST00000091848.5
Akr1e1

aldo-keto reductase family 1, member E1

chr1_+_163779575 0.105 ENSMUST00000027877.6
ENSMUST00000077642.5
Kifap3

kinesin-associated protein 3

chr2_-_28583189 0.105 ENSMUST00000113889.2
Gtf3c5
general transcription factor IIIC, polypeptide 5
chr2_-_28583239 0.103 ENSMUST00000028157.8
Gtf3c5
general transcription factor IIIC, polypeptide 5
chr18_-_6241486 0.092 ENSMUST00000025083.7
Kif5b
kinesin family member 5B
chrX_+_106027300 0.088 ENSMUST00000055941.6
Atp7a
ATPase, Cu++ transporting, alpha polypeptide
chr10_+_52022502 0.086 ENSMUST00000163017.1
ENSMUST00000058347.4
Vgll2

vestigial like 2 homolog (Drosophila)

chr10_+_102158858 0.086 ENSMUST00000138522.1
ENSMUST00000163753.1
ENSMUST00000138016.1
Mgat4c


mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)


chr7_+_43672003 0.082 ENSMUST00000038332.8
Ctu1
cytosolic thiouridylase subunit 1 homolog (S. pombe)
chr13_+_94976435 0.081 ENSMUST00000160409.1
ENSMUST00000159647.1
ENSMUST00000167155.1
Wdr41


WD repeat domain 41


chrX_+_106027259 0.081 ENSMUST00000113557.1
Atp7a
ATPase, Cu++ transporting, alpha polypeptide
chr2_-_155930190 0.078 ENSMUST00000109636.4
ENSMUST00000109631.1
Uqcc1

ubiquinol-cytochrome c reductase complex assembly factor 1

chr2_-_155930018 0.078 ENSMUST00000152766.1
ENSMUST00000139232.1
ENSMUST00000109632.1
ENSMUST00000006036.6
ENSMUST00000142655.1
ENSMUST00000159238.1
Uqcc1





ubiquinol-cytochrome c reductase complex assembly factor 1





chr15_+_99006056 0.077 ENSMUST00000079818.3
Gm8973
predicted gene 8973
chr16_-_63864114 0.073 ENSMUST00000064405.6
Epha3
Eph receptor A3
chr3_+_106034661 0.073 ENSMUST00000170669.2
Gm4540
predicted gene 4540
chr3_+_88716884 0.072 ENSMUST00000172252.1
Rit1
Ras-like without CAAX 1
chr15_+_80711292 0.070 ENSMUST00000067689.7
Tnrc6b
trinucleotide repeat containing 6b
chr17_-_45686899 0.068 ENSMUST00000156254.1
Tmem63b
transmembrane protein 63b
chr2_-_12419456 0.068 ENSMUST00000154899.1
ENSMUST00000028105.6
Fam188a

family with sequence similarity 188, member A

chr15_-_36496722 0.059 ENSMUST00000057486.7
Ankrd46
ankyrin repeat domain 46
chr8_+_93810832 0.059 ENSMUST00000034198.8
ENSMUST00000125716.1
Gnao1

guanine nucleotide binding protein, alpha O

chr5_-_118244861 0.054 ENSMUST00000117177.1
ENSMUST00000133372.1
ENSMUST00000154786.1
ENSMUST00000121369.1
Rnft2



ring finger protein, transmembrane 2



chr12_-_87444017 0.052 ENSMUST00000091090.4
2700073G19Rik
RIKEN cDNA 2700073G19 gene
chr8_-_85432841 0.051 ENSMUST00000047749.5
4921524J17Rik
RIKEN cDNA 4921524J17 gene
chr15_-_102510681 0.049 ENSMUST00000171565.1
Map3k12
mitogen-activated protein kinase kinase kinase 12
chr13_-_23934156 0.045 ENSMUST00000052776.2
Hist1h2ba
histone cluster 1, H2ba
chr9_-_53667429 0.040 ENSMUST00000166367.1
ENSMUST00000034529.7
Cul5

cullin 5

chr11_+_72689997 0.037 ENSMUST00000155998.1
Ankfy1
ankyrin repeat and FYVE domain containing 1
chr6_+_37870786 0.037 ENSMUST00000120428.1
ENSMUST00000031859.7
Trim24

tripartite motif-containing 24

chr15_-_33687840 0.037 ENSMUST00000042021.3
Tspyl5
testis-specific protein, Y-encoded-like 5
chr11_+_17257558 0.036 ENSMUST00000000594.2
ENSMUST00000156784.1
C1d

C1D nuclear receptor co-repressor

chr13_+_23555023 0.035 ENSMUST00000045301.6
Hist1h1d
histone cluster 1, H1d
chr2_-_93452679 0.030 ENSMUST00000111257.1
ENSMUST00000145553.1
Cd82

CD82 antigen

chr12_-_84617326 0.030 ENSMUST00000021666.4
Abcd4
ATP-binding cassette, sub-family D (ALD), member 4
chr2_-_12419387 0.029 ENSMUST00000124515.1
Fam188a
family with sequence similarity 188, member A
chr17_+_46772635 0.025 ENSMUST00000071430.5
2310039H08Rik
RIKEN cDNA 2310039H08 gene
chr3_-_37125943 0.025 ENSMUST00000029275.5
Il2
interleukin 2
chr4_-_134245579 0.025 ENSMUST00000030644.7
Zfp593
zinc finger protein 593
chr4_+_41966058 0.024 ENSMUST00000108026.2
Gm20938
predicted gene, 20938
chrX_-_134111852 0.024 ENSMUST00000033610.6
Nox1
NADPH oxidase 1
chr1_-_63176653 0.013 ENSMUST00000027111.8
ENSMUST00000168099.2
Ndufs1

NADH dehydrogenase (ubiquinone) Fe-S protein 1


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.8 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.8 2.3 GO:2000564 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.5 1.6 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.3 0.8 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.2 1.7 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.2 0.6 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.2 0.8 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.2 0.6 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.2 1.4 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.2 0.8 GO:0070295 renal water absorption(GO:0070295)
0.2 1.8 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 0.6 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.1 0.4 GO:0050787 glycolate metabolic process(GO:0009441) enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) glycolate biosynthetic process(GO:0046295) detoxification of mercury ion(GO:0050787) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of cellular amino acid biosynthetic process(GO:2000284)
0.1 0.6 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.1 0.5 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.1 1.3 GO:0015816 glycine transport(GO:0015816)
0.1 0.3 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1 0.3 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.2 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 0.6 GO:0015862 uridine transport(GO:0015862)
0.1 0.4 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 0.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.7 GO:0036159 outer dynein arm assembly(GO:0036158) inner dynein arm assembly(GO:0036159)
0.1 0.2 GO:0031038 myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519)
0.1 0.2 GO:1904959 elastin biosynthetic process(GO:0051542) copper ion export(GO:0060003) regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959)
0.1 0.2 GO:1905034 regulation of antifungal innate immune response(GO:1905034) negative regulation of antifungal innate immune response(GO:1905035)
0.1 0.3 GO:1902995 apolipoprotein A-I-mediated signaling pathway(GO:0038027) regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995) positive regulation of apoptotic cell clearance(GO:2000427)
0.1 0.3 GO:0051189 molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.1 GO:0097360 negative regulation of mitochondrial depolarization(GO:0051902) chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382) negative regulation of membrane depolarization(GO:1904180)
0.0 0.4 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 3.2 GO:0009063 cellular amino acid catabolic process(GO:0009063)
0.0 0.6 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 0.9 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0072014 proximal tubule development(GO:0072014)
0.0 0.4 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.2 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.2 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.2 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.4 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.2 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 2.1 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.4 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.3 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.2 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.3 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.2 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.1 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.0 0.9 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.1 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 0.2 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.1 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.3 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 1.5 GO:0042742 defense response to bacterium(GO:0042742)
0.0 0.2 GO:0006953 acute-phase response(GO:0006953)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.4 7.8 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.2 0.6 GO:0043512 inhibin A complex(GO:0043512)
0.2 2.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.3 GO:0031362 intrinsic component of external side of plasma membrane(GO:0031233) anchored component of external side of plasma membrane(GO:0031362)
0.1 0.3 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.7 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:1990075 kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 1.6 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.3 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.6 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.7 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.4 GO:0070469 respiratory chain(GO:0070469)
0.0 0.8 GO:0030315 T-tubule(GO:0030315)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.8 3.2 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.3 2.3 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.2 7.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 0.6 GO:0098809 nitrite reductase activity(GO:0098809)
0.1 0.4 GO:0036470 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.1 1.3 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 1.6 GO:0001618 virus receptor activity(GO:0001618)
0.1 0.8 GO:0098821 BMP receptor activity(GO:0098821)
0.1 0.8 GO:0015288 porin activity(GO:0015288)
0.1 0.6 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.3 GO:0051870 methotrexate binding(GO:0051870)
0.1 0.3 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 1.1 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 0.2 GO:0000992 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.1 0.4 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 0.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.1 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 0.2 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 0.2 GO:0043682 copper-exporting ATPase activity(GO:0004008) superoxide dismutase copper chaperone activity(GO:0016532) copper-transporting ATPase activity(GO:0043682)
0.1 1.7 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 1.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 2.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.3 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.8 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.3 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 1.0 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.6 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.4 GO:0016208 AMP binding(GO:0016208)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 0.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 1.0 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.5 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0 0.1 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.6 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.3 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 8.4 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 1.9 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 1.7 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 2.3 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.4 PID_ALK1_PATHWAY ALK1 signaling events
0.0 0.8 PID_BMP_PATHWAY BMP receptor signaling
0.0 1.7 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 7.8 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 0.6 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.1 1.1 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 1.7 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.8 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 0.7 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 0.7 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.1 1.6 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.2 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.6 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.0 0.6 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.3 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.2 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.6 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.2 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.6 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.2 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 2.3 REACTOME_SIGNALING_BY_ERBB2 Genes involved in Signaling by ERBB2
0.0 0.4 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.0 0.6 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.3 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.5 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis