Motif ID: Pbx2

Z-value: 0.639


Transcription factors associated with Pbx2:

Gene SymbolEntrez IDGene Name
Pbx2 ENSMUSG00000034673.8 Pbx2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pbx2mm10_v2_chr17_+_34593388_34593417-0.552.0e-04Click!


Activity profile for motif Pbx2.

activity profile for motif Pbx2


Sorted Z-values histogram for motif Pbx2

Sorted Z-values for motif Pbx2



Network of associatons between targets according to the STRING database.



First level regulatory network of Pbx2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_66812593 3.858 ENSMUST00000100572.3
Sla
src-like adaptor
chr5_+_106609098 2.455 ENSMUST00000167618.1
Gm17304
predicted gene, 17304
chr3_+_121953213 2.402 ENSMUST00000037958.7
ENSMUST00000128366.1
Arhgap29

Rho GTPase activating protein 29

chr9_-_54661870 2.255 ENSMUST00000034822.5
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr1_-_56972437 2.253 ENSMUST00000042857.7
Satb2
special AT-rich sequence binding protein 2
chr17_+_78508063 2.162 ENSMUST00000024880.9
Vit
vitrin
chr9_-_54661666 1.764 ENSMUST00000128624.1
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr11_-_79504078 1.681 ENSMUST00000164465.2
Omg
oligodendrocyte myelin glycoprotein
chr6_+_8259288 1.597 ENSMUST00000159335.1
Gm16039
predicted gene 16039
chr15_+_21111452 1.590 ENSMUST00000075132.6
Cdh12
cadherin 12
chr8_+_72646679 1.526 ENSMUST00000161386.1
ENSMUST00000093427.4
Nwd1

NACHT and WD repeat domain containing 1

chr8_+_72646728 1.348 ENSMUST00000161254.1
Nwd1
NACHT and WD repeat domain containing 1
chr3_-_152982240 1.343 ENSMUST00000044278.5
St6galnac5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr2_-_104257400 1.310 ENSMUST00000141159.1
D430041D05Rik
RIKEN cDNA D430041D05 gene
chr14_+_65969714 1.220 ENSMUST00000153460.1
Clu
clusterin
chr6_-_8259098 1.185 ENSMUST00000012627.4
Rpa3
replication protein A3
chr11_+_3330401 1.160 ENSMUST00000045153.4
Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr11_+_3330781 1.129 ENSMUST00000136536.1
ENSMUST00000093399.4
Pik3ip1

phosphoinositide-3-kinase interacting protein 1

chrX_+_140367494 1.092 ENSMUST00000141660.1
Frmpd3
FERM and PDZ domain containing 3
chr3_+_68572245 1.035 ENSMUST00000170788.2
Schip1
schwannomin interacting protein 1
chr12_+_108334341 0.983 ENSMUST00000021684.4
Cyp46a1
cytochrome P450, family 46, subfamily a, polypeptide 1
chr19_-_36919606 0.961 ENSMUST00000057337.7
Fgfbp3
fibroblast growth factor binding protein 3
chr6_+_8259327 0.923 ENSMUST00000159378.1
Gm16039
predicted gene 16039
chr13_-_113663670 0.907 ENSMUST00000054650.4
Hspb3
heat shock protein 3
chr6_+_8259379 0.902 ENSMUST00000162034.1
ENSMUST00000160705.1
ENSMUST00000159433.1
Gm16039


predicted gene 16039


chr2_-_58052832 0.902 ENSMUST00000090940.5
Ermn
ermin, ERM-like protein
chr2_+_65620829 0.856 ENSMUST00000028377.7
Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr18_-_31820413 0.735 ENSMUST00000165131.2
Gm6665
predicted gene 6665
chr11_+_97685794 0.713 ENSMUST00000107584.1
ENSMUST00000107585.2
Cisd3

CDGSH iron sulfur domain 3

chr2_+_106695594 0.692 ENSMUST00000016530.7
Mpped2
metallophosphoesterase domain containing 2
chr15_+_92597104 0.674 ENSMUST00000035399.8
Pdzrn4
PDZ domain containing RING finger 4
chr15_+_74563738 0.664 ENSMUST00000170845.1
Bai1
brain-specific angiogenesis inhibitor 1
chr9_-_89705017 0.653 ENSMUST00000058488.6
Tmed3
transmembrane emp24 domain containing 3
chr1_+_169928648 0.645 ENSMUST00000094348.3
1700084C01Rik
RIKEN cDNA 1700084C01 gene
chr7_-_43505926 0.644 ENSMUST00000013497.1
ENSMUST00000163619.1
4931406B18Rik

RIKEN cDNA 4931406B18 gene

chr2_+_128967383 0.640 ENSMUST00000110320.2
ENSMUST00000110319.2
Zc3h6

zinc finger CCCH type containing 6

chr8_+_93810832 0.607 ENSMUST00000034198.8
ENSMUST00000125716.1
Gnao1

guanine nucleotide binding protein, alpha O

chr12_+_76255209 0.598 ENSMUST00000021443.5
Mthfd1
methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase
chr4_+_98546710 0.597 ENSMUST00000102792.3
Inadl
InaD-like (Drosophila)
chr15_+_85510812 0.592 ENSMUST00000079690.2
Gm4825
predicted pseudogene 4825
chr9_-_42399709 0.532 ENSMUST00000160940.1
Tecta
tectorin alpha
chr16_-_91728701 0.518 ENSMUST00000114023.2
ENSMUST00000117644.1
Cryzl1

crystallin, zeta (quinone reductase)-like 1

chr11_-_120643643 0.507 ENSMUST00000141254.1
ENSMUST00000170556.1
ENSMUST00000151876.1
ENSMUST00000026133.8
ENSMUST00000139706.1
Pycr1




pyrroline-5-carboxylate reductase 1




chr9_+_112234257 0.478 ENSMUST00000149308.3
ENSMUST00000144424.2
ENSMUST00000139552.2
2900079G21Rik


RIKEN cDNA 2900079G21 gene


chr4_+_98546919 0.444 ENSMUST00000030290.7
Inadl
InaD-like (Drosophila)
chr4_+_132768325 0.406 ENSMUST00000102561.4
Rpa2
replication protein A2
chrX_+_73064787 0.391 ENSMUST00000060418.6
Pnma3
paraneoplastic antigen MA3
chr2_+_175275125 0.372 ENSMUST00000109051.1
Gm14440
predicted gene 14440
chr11_-_110095937 0.369 ENSMUST00000106664.3
ENSMUST00000046223.7
ENSMUST00000106662.1
Abca8a


ATP-binding cassette, sub-family A (ABC1), member 8a


chrX_-_8175890 0.348 ENSMUST00000143984.1
Tbc1d25
TBC1 domain family, member 25
chr1_-_45503282 0.343 ENSMUST00000086430.4
Col5a2
collagen, type V, alpha 2
chr3_+_79884496 0.342 ENSMUST00000118853.1
Fam198b
family with sequence similarity 198, member B
chrX_+_38600626 0.333 ENSMUST00000000365.2
Mcts1
malignant T cell amplified sequence 1
chr5_-_109691041 0.323 ENSMUST00000092720.3
5430403G16Rik
RIKEN cDNA 5430403G16 gene
chr7_-_104950441 0.309 ENSMUST00000179862.1
Gm5900
predicted pseudogene 5900
chrX_+_134295225 0.308 ENSMUST00000037687.7
Tmem35
transmembrane protein 35
chrX_+_56779699 0.306 ENSMUST00000114772.2
ENSMUST00000114768.3
ENSMUST00000155882.1
Fhl1


four and a half LIM domains 1


chr14_+_11227511 0.303 ENSMUST00000080237.3
Rpl21-ps4
ribosomal protein L21, pseudogene 4
chr2_+_177897096 0.299 ENSMUST00000108935.1
Gm14327
predicted gene 14327
chr4_+_141242850 0.282 ENSMUST00000138096.1
ENSMUST00000006618.2
ENSMUST00000125392.1
Arhgef19


Rho guanine nucleotide exchange factor (GEF) 19


chr6_-_143947092 0.265 ENSMUST00000144289.1
ENSMUST00000111748.1
Sox5

SRY-box containing gene 5

chr19_-_32061438 0.256 ENSMUST00000096119.4
Asah2
N-acylsphingosine amidohydrolase 2
chr14_+_30825580 0.256 ENSMUST00000006701.5
Tmem110
transmembrane protein 110
chrX_-_70365052 0.254 ENSMUST00000101509.2
Ids
iduronate 2-sulfatase
chr7_+_49974864 0.254 ENSMUST00000081872.5
ENSMUST00000151721.1
Nell1

NEL-like 1

chr4_+_147492417 0.254 ENSMUST00000105721.2
Gm13152
predicted gene 13152
chr4_-_150003130 0.248 ENSMUST00000084117.6
H6pd
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr10_+_78425670 0.244 ENSMUST00000005185.6
Cstb
cystatin B
chr18_+_37725706 0.238 ENSMUST00000066149.6
Pcdhga9
protocadherin gamma subfamily A, 9
chr9_+_92309362 0.233 ENSMUST00000098477.1
ENSMUST00000150594.1
1700057G04Rik

RIKEN cDNA 1700057G04 gene

chr16_-_37384915 0.227 ENSMUST00000114787.1
ENSMUST00000114782.1
ENSMUST00000023526.2
ENSMUST00000114775.1
Stxbp5l



syntaxin binding protein 5-like



chr11_+_49247462 0.222 ENSMUST00000109194.1
Mgat1
mannoside acetylglucosaminyltransferase 1
chr4_+_15881255 0.219 ENSMUST00000029876.1
Calb1
calbindin 1
chr17_+_8849974 0.216 ENSMUST00000115720.1
Pde10a
phosphodiesterase 10A
chr7_+_119690026 0.205 ENSMUST00000047045.8
Acsm4
acyl-CoA synthetase medium-chain family member 4
chr2_-_86347764 0.187 ENSMUST00000099894.2
Olfr1055
olfactory receptor 1055
chrX_+_56779437 0.177 ENSMUST00000114773.3
Fhl1
four and a half LIM domains 1
chr3_-_39359128 0.173 ENSMUST00000056409.2
Gm9845
predicted pseudogene 9845
chrX_+_20364481 0.168 ENSMUST00000033372.6
ENSMUST00000115391.1
ENSMUST00000115387.1
Rp2h


retinitis pigmentosa 2 homolog (human)


chr2_-_177925604 0.160 ENSMUST00000108934.2
ENSMUST00000081529.4
C330013J21Rik

RIKEN cDNA C330013J21 gene

chr8_-_54724317 0.155 ENSMUST00000129132.2
ENSMUST00000150488.1
ENSMUST00000127511.2
Wdr17


WD repeat domain 17


chr9_-_108263706 0.153 ENSMUST00000171412.1
Dag1
dystroglycan 1
chr1_+_137928100 0.149 ENSMUST00000054333.2
A130050O07Rik
RIKEN cDNA A130050O07 gene
chr2_-_25224653 0.149 ENSMUST00000043584.4
Tubb4b
tubulin, beta 4B class IVB
chr9_+_113930934 0.147 ENSMUST00000084885.5
ENSMUST00000009885.7
Ubp1

upstream binding protein 1

chr2_-_175175871 0.145 ENSMUST00000109054.2
Gm14443
predicted gene 14443
chr5_+_8660059 0.140 ENSMUST00000047753.4
Abcb1a
ATP-binding cassette, sub-family B (MDR/TAP), member 1A
chr1_+_164275559 0.140 ENSMUST00000027867.6
Ccdc181
coiled-coil domain containing 181
chr18_-_73754457 0.134 ENSMUST00000041138.2
Elac1
elaC homolog 1 (E. coli)
chr6_-_143947061 0.133 ENSMUST00000124233.1
Sox5
SRY-box containing gene 5
chr14_+_55015454 0.130 ENSMUST00000022815.8
Ngdn
neuroguidin, EIF4E binding protein
chr2_-_128967725 0.129 ENSMUST00000099385.2
Gm10762
predicted gene 10762
chr9_+_35423582 0.128 ENSMUST00000154652.1
Cdon
cell adhesion molecule-related/down-regulated by oncogenes
chr1_-_147281942 0.125 ENSMUST00000066758.2
Gm9931
predicted gene 9931
chr2_+_119594288 0.123 ENSMUST00000147425.1
ENSMUST00000153581.1
1700020I14Rik

RIKEN cDNA 1700020I14 gene

chr2_+_55411790 0.116 ENSMUST00000155997.1
ENSMUST00000128307.1
Gm14033

predicted gene 14033

chr17_-_24527830 0.114 ENSMUST00000176353.1
ENSMUST00000176237.1
Traf7

TNF receptor-associated factor 7

chr2_+_177464733 0.114 ENSMUST00000099002.3
ENSMUST00000108952.3
Gm14420

predicted gene 14420

chr8_-_54724474 0.114 ENSMUST00000175915.1
Wdr17
WD repeat domain 17
chr17_-_24527925 0.112 ENSMUST00000176652.1
Traf7
TNF receptor-associated factor 7
chr12_+_71015966 0.108 ENSMUST00000046305.5
Arid4a
AT rich interactive domain 4A (RBP1-like)
chr3_+_19957037 0.101 ENSMUST00000091309.5
ENSMUST00000108329.1
ENSMUST00000003714.6
Cp


ceruloplasmin


chr11_-_79296906 0.094 ENSMUST00000068448.2
Gm9964
predicted gene 9964
chr3_-_37125943 0.092 ENSMUST00000029275.5
Il2
interleukin 2
chr17_+_24720063 0.092 ENSMUST00000170715.1
ENSMUST00000054289.6
ENSMUST00000146867.1
Rps2


ribosomal protein S2


chr9_+_54538984 0.092 ENSMUST00000060242.5
ENSMUST00000118413.1
Sh2d7

SH2 domain containing 7

chr9_+_119341294 0.091 ENSMUST00000039784.5
Acaa1a
acetyl-Coenzyme A acyltransferase 1A
chr7_-_18432033 0.090 ENSMUST00000019291.6
Psg28
pregnancy-specific glycoprotein 28
chr5_+_52783055 0.088 ENSMUST00000113904.2
ENSMUST00000031077.8
Zcchc4

zinc finger, CCHC domain containing 4

chr5_-_114773488 0.078 ENSMUST00000178440.1
ENSMUST00000043283.7
ENSMUST00000112185.2
Git2


G protein-coupled receptor kinase-interactor 2


chrX_-_36874111 0.078 ENSMUST00000047486.5
C330007P06Rik
RIKEN cDNA C330007P06 gene
chr3_-_106790143 0.076 ENSMUST00000038845.8
Cd53
CD53 antigen
chr13_-_98316967 0.067 ENSMUST00000022163.8
ENSMUST00000152704.1
Btf3

basic transcription factor 3

chr10_-_39122277 0.067 ENSMUST00000136546.1
Fam229b
family with sequence similarity 229, member B
chr5_+_24394388 0.065 ENSMUST00000115074.1
Abcb8
ATP-binding cassette, sub-family B (MDR/TAP), member 8
chr3_+_122729158 0.061 ENSMUST00000066728.5
Pde5a
phosphodiesterase 5A, cGMP-specific
chr17_+_24886643 0.056 ENSMUST00000117890.1
ENSMUST00000168265.1
ENSMUST00000120943.1
ENSMUST00000068508.6
ENSMUST00000119829.1
Spsb3




splA/ryanodine receptor domain and SOCS box containing 3




chr2_-_132578244 0.047 ENSMUST00000110142.1
Gpcpd1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr11_+_97685903 0.045 ENSMUST00000107583.2
Cisd3
CDGSH iron sulfur domain 3
chrX_-_134541847 0.044 ENSMUST00000054213.4
Timm8a1
translocase of inner mitochondrial membrane 8A1
chr11_-_115133981 0.040 ENSMUST00000106561.1
ENSMUST00000051264.7
ENSMUST00000106562.2
Cd300lf


CD300 antigen like family member F


chr13_+_3538075 0.036 ENSMUST00000059515.6
Gdi2
guanosine diphosphate (GDP) dissociation inhibitor 2
chr11_-_110251736 0.035 ENSMUST00000044003.7
Abca6
ATP-binding cassette, sub-family A (ABC1), member 6
chr5_-_114773372 0.034 ENSMUST00000112183.1
ENSMUST00000086564.4
Git2

G protein-coupled receptor kinase-interactor 2

chr12_-_8499985 0.023 ENSMUST00000067384.4
Rhob
ras homolog gene family, member B
chr6_-_115853346 0.018 ENSMUST00000032469.6
Mbd4
methyl-CpG binding domain protein 4
chr17_+_37193889 0.014 ENSMUST00000038844.6
Ubd
ubiquitin D
chr14_-_7483762 0.013 ENSMUST00000164366.1
Gm3752
predicted gene 3752
chr14_+_61599493 0.010 ENSMUST00000039562.6
Trim13
tripartite motif-containing 13
chr19_-_3575708 0.008 ENSMUST00000113997.2
ENSMUST00000025846.8
ENSMUST00000172362.1
Ppp6r3


protein phosphatase 6, regulatory subunit 3


chr13_+_60602182 0.008 ENSMUST00000044083.7
Dapk1
death associated protein kinase 1
chr10_+_14523062 0.006 ENSMUST00000096020.5
Gm10335
predicted gene 10335
chr5_-_20951769 0.005 ENSMUST00000036489.5
Rsbn1l
round spermatid basic protein 1-like
chr18_+_77938452 0.004 ENSMUST00000044622.5
Epg5
ectopic P-granules autophagy protein 5 homolog (C. elegans)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.3 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 1.2 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 0.6 GO:0006547 histidine metabolic process(GO:0006547)
0.1 2.3 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 1.0 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 0.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 4.1 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.1 1.0 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 1.3 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 1.7 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.1 0.3 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.5 GO:0006561 proline biosynthetic process(GO:0006561)
0.1 0.4 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 0.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1 1.0 GO:0001553 luteinization(GO:0001553)
0.1 1.4 GO:0006298 mismatch repair(GO:0006298)
0.1 3.8 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.2 GO:0072235 distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235)
0.0 0.2 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.0 0.1 GO:0046618 drug export(GO:0046618)
0.0 0.2 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.3 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.0 0.1 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678)
0.0 0.1 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.3 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013) negative regulation of T-helper 17 type immune response(GO:2000317) regulation of T-helper 17 cell differentiation(GO:2000319) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.0 0.0 GO:0035963 response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.0 0.1 GO:0034773 histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.0 2.1 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.2 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.1 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.6 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 1.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.5 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 0.1 GO:0001731 formation of translation preinitiation complex(GO:0001731)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.1 2.2 GO:0005614 interstitial matrix(GO:0005614)
0.1 2.9 GO:0005682 U5 snRNP(GO:0005682)
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.9 GO:0033269 internode region of axon(GO:0033269)
0.1 1.6 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.7 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 4.4 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.2 GO:0016011 dystroglycan complex(GO:0016011)
0.0 4.1 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 2.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 2.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.4 4.0 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 0.6 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.2 1.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.5 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.6 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 3.2 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 0.2 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.1 0.2 GO:0003996 acyl-CoA ligase activity(GO:0003996) fatty-acyl-CoA synthase activity(GO:0004321)
0.1 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 1.2 GO:0051787 misfolded protein binding(GO:0051787)
0.0 1.0 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.0 1.1 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.2 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.4 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559) phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0 0.8 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.1 GO:0008410 CoA-transferase activity(GO:0008410)
0.0 0.3 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.2 GO:0043237 laminin-1 binding(GO:0043237)
0.0 1.1 GO:0003684 damaged DNA binding(GO:0003684)
0.0 2.4 GO:0005539 glycosaminoglycan binding(GO:0005539)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.0 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 1.6 GO:0030165 PDZ domain binding(GO:0030165)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 0.2 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.0 2.9 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 3.2 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.0 1.3 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 3.3 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 1.0 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.0 1.0 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 1.1 REACTOME_CELL_CELL_JUNCTION_ORGANIZATION Genes involved in Cell-cell junction organization
0.0 1.3 REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.5 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.3 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.0 0.6 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.0 2.5 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.2 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.3 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects