Motif ID: Pitx3

Z-value: 0.937


Transcription factors associated with Pitx3:

Gene SymbolEntrez IDGene Name
Pitx3 ENSMUSG00000025229.9 Pitx3



Activity profile for motif Pitx3.

activity profile for motif Pitx3


Sorted Z-values histogram for motif Pitx3

Sorted Z-values for motif Pitx3



Network of associatons between targets according to the STRING database.



First level regulatory network of Pitx3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_62899118 6.337 ENSMUST00000174189.1
Tet1
tet methylcytosine dioxygenase 1
chr3_+_86070915 3.601 ENSMUST00000182666.1
Sh3d19
SH3 domain protein D19
chr8_+_65967157 3.301 ENSMUST00000072482.6
March1
membrane-associated ring finger (C3HC4) 1
chr18_+_64254359 3.007 ENSMUST00000025477.7
St8sia3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr16_+_17276291 2.989 ENSMUST00000164950.1
ENSMUST00000159242.1
Tmem191c

transmembrane protein 191C

chr13_-_12464925 2.984 ENSMUST00000124888.1
Lgals8
lectin, galactose binding, soluble 8
chrX_+_142226765 2.878 ENSMUST00000112916.2
Nxt2
nuclear transport factor 2-like export factor 2
chr17_-_32800938 2.871 ENSMUST00000080905.6
Zfp811
zinc finger protein 811
chr10_+_81718919 2.754 ENSMUST00000085664.5
Zfp433
RIKEN cDNA 1700123A16 gene
chr11_-_100770926 2.714 ENSMUST00000139341.1
ENSMUST00000017891.7
Ghdc

GH3 domain containing

chr2_-_132578128 2.711 ENSMUST00000028822.7
Gpcpd1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr8_+_69300776 2.633 ENSMUST00000078257.6
D130040H23Rik
RIKEN cDNA D130040H23 gene
chr2_-_132578244 2.613 ENSMUST00000110142.1
Gpcpd1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr10_-_53379816 2.598 ENSMUST00000095691.5
Cep85l
centrosomal protein 85-like
chr9_+_118506226 2.569 ENSMUST00000084820.4
Golga4
golgi autoantigen, golgin subfamily a, 4
chr11_-_79296906 2.555 ENSMUST00000068448.2
Gm9964
predicted gene 9964
chr2_-_132578155 2.514 ENSMUST00000110136.1
ENSMUST00000124107.1
ENSMUST00000060955.5
Gpcpd1


glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)


chr5_+_3571664 2.509 ENSMUST00000008451.5
1700109H08Rik
RIKEN cDNA 1700109H08 gene
chrX_+_7909542 2.480 ENSMUST00000086274.2
Gm10490
predicted gene 10490
chr5_+_90759299 2.377 ENSMUST00000031318.4
Cxcl5
chemokine (C-X-C motif) ligand 5
chr1_-_186705980 2.348 ENSMUST00000045288.8
Tgfb2
transforming growth factor, beta 2
chr13_-_67609617 2.267 ENSMUST00000138725.1
AA987161
expressed sequence AA987161
chr7_+_18987518 2.260 ENSMUST00000063563.7
Nanos2
nanos homolog 2 (Drosophila)
chr2_+_127008711 2.248 ENSMUST00000110394.1
ENSMUST00000002063.8
Ap4e1

adaptor-related protein complex AP-4, epsilon 1

chr9_-_15357692 2.231 ENSMUST00000098979.3
ENSMUST00000161132.1
5830418K08Rik

RIKEN cDNA 5830418K08 gene

chr10_-_68278713 2.209 ENSMUST00000020106.7
Arid5b
AT rich interactive domain 5B (MRF1-like)
chr13_-_77131276 2.180 ENSMUST00000159300.1
Ankrd32
ankyrin repeat domain 32
chr11_-_62457772 2.160 ENSMUST00000127471.2
Ncor1
nuclear receptor co-repressor 1
chrX_-_103623648 2.144 ENSMUST00000156211.1
Ftx
Ftx transcript, Xist regulator (non-protein coding)
chr13_-_67061131 2.056 ENSMUST00000167565.1
Zfp712
zinc finger protein 712
chr19_+_7494033 2.042 ENSMUST00000170373.1
Atl3
atlastin GTPase 3
chr13_-_97747399 1.965 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr4_-_32923455 1.961 ENSMUST00000035719.4
ENSMUST00000084749.1
Ankrd6

ankyrin repeat domain 6

chr13_-_67609667 1.897 ENSMUST00000012873.8
AA987161
expressed sequence AA987161
chr9_-_22307638 1.887 ENSMUST00000086278.6
Zfp810
zinc finger protein 810
chr16_-_38341812 1.877 ENSMUST00000114740.2
ENSMUST00000023501.8
Maats1

MYCBP-associated, testis expressed 1

chr7_-_80324418 1.866 ENSMUST00000047362.4
ENSMUST00000121882.1
Rccd1

RCC1 domain containing 1

chr7_+_131410601 1.866 ENSMUST00000015829.7
ENSMUST00000117518.1
Acadsb

acyl-Coenzyme A dehydrogenase, short/branched chain

chr11_-_100472725 1.861 ENSMUST00000056665.3
Klhl11
kelch-like 11
chr3_-_88456397 1.858 ENSMUST00000141471.1
ENSMUST00000123753.1
Sema4a

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A

chr4_+_138775735 1.854 ENSMUST00000030528.2
Pla2g2d
phospholipase A2, group IID
chr5_+_122643878 1.843 ENSMUST00000100737.3
ENSMUST00000121489.1
ENSMUST00000031425.8
ENSMUST00000086247.5
P2rx7



purinergic receptor P2X, ligand-gated ion channel, 7



chr17_-_6079693 1.782 ENSMUST00000024570.5
ENSMUST00000097432.3
Serac1

serine active site containing 1

chr12_+_51348019 1.753 ENSMUST00000054308.6
G2e3
G2/M-phase specific E3 ubiquitin ligase
chr5_-_62766153 1.738 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr2_-_156007919 1.729 ENSMUST00000086145.3
ENSMUST00000144686.1
ENSMUST00000140657.1
6430550D23Rik


RIKEN cDNA 6430550D23 gene


chr10_+_111164794 1.723 ENSMUST00000105275.1
ENSMUST00000095310.1
Osbpl8

oxysterol binding protein-like 8

chr10_+_81661998 1.721 ENSMUST00000105315.2
Gm10778
predicted gene 10778
chr2_-_73312701 1.719 ENSMUST00000058615.9
Cir1
corepressor interacting with RBPJ, 1
chr9_-_62070606 1.699 ENSMUST00000034785.7
Glce
glucuronyl C5-epimerase
chrX_+_159532655 1.698 ENSMUST00000112464.1
A830080D01Rik
RIKEN cDNA A830080D01 gene
chr2_+_28506095 1.697 ENSMUST00000074761.4
Gm10134
predicted gene 10134
chr5_-_143895025 1.663 ENSMUST00000079624.5
ENSMUST00000110717.2
Ankrd61

ankyrin repeat domain 61

chrX_-_37104523 1.647 ENSMUST00000130324.1
Upf3b
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr1_-_153408429 1.645 ENSMUST00000097535.4
E330020D12Rik
Riken cDNA E330020D12 gene
chr10_+_79996479 1.640 ENSMUST00000132517.1
Abca7
ATP-binding cassette, sub-family A (ABC1), member 7
chr7_-_81855794 1.632 ENSMUST00000085094.3
Gm10160
predicted gene 10160
chr13_-_74482943 1.620 ENSMUST00000074369.6
Zfp825
zinc finger protein 825
chr5_+_138280538 1.616 ENSMUST00000162245.1
ENSMUST00000161691.1
Stag3

stromal antigen 3

chr15_+_80287234 1.612 ENSMUST00000160424.1
Cacna1i
calcium channel, voltage-dependent, alpha 1I subunit
chr10_+_128499364 1.610 ENSMUST00000180477.1
A430046D13Rik
Riken cDNA A430046D13 gene
chr18_-_22850738 1.608 ENSMUST00000092015.4
ENSMUST00000069215.6
Nol4

nucleolar protein 4

chr16_+_17276337 1.570 ENSMUST00000159065.1
ENSMUST00000159494.1
ENSMUST00000159811.1
Tmem191c


transmembrane protein 191C


chr19_-_61176309 1.569 ENSMUST00000180168.1
Gm7102
predicted gene 7102
chr12_-_87775755 1.560 ENSMUST00000164517.2
Gm21319
predicted gene, 21319
chrX_+_101640056 1.558 ENSMUST00000119299.1
ENSMUST00000044475.4
Ogt

O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)

chr3_-_152340350 1.558 ENSMUST00000073089.6
ENSMUST00000068243.6
Fam73a

family with sequence similarity 73, member A

chr6_+_71493850 1.534 ENSMUST00000064637.4
ENSMUST00000114178.1
Rnf103

ring finger protein 103

chr1_-_157256682 1.534 ENSMUST00000134543.1
Rasal2
RAS protein activator like 2
chr5_-_134456702 1.534 ENSMUST00000073161.5
ENSMUST00000171794.2
ENSMUST00000111245.2
ENSMUST00000100654.3
ENSMUST00000167084.2
ENSMUST00000100652.3
ENSMUST00000100650.3
ENSMUST00000074114.5
Gtf2ird1







general transcription factor II I repeat domain-containing 1







chr13_-_100104064 1.524 ENSMUST00000038104.5
Bdp1
B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
chr10_+_39612934 1.523 ENSMUST00000019987.6
Traf3ip2
TRAF3 interacting protein 2
chr7_-_46667375 1.518 ENSMUST00000107669.2
Tph1
tryptophan hydroxylase 1
chr1_-_58586191 1.511 ENSMUST00000038372.7
ENSMUST00000097724.3
ENSMUST00000161000.1
ENSMUST00000161600.1
Fam126b



family with sequence similarity 126, member B



chr9_-_73039697 1.505 ENSMUST00000184035.1
ENSMUST00000098566.4
Pigb

phosphatidylinositol glycan anchor biosynthesis, class B

chr13_-_23430826 1.485 ENSMUST00000153753.1
ENSMUST00000141543.1
C230035I16Rik

RIKEN cDNA C230035I16 gene

chr7_+_24257644 1.484 ENSMUST00000072713.6
Zfp108
zinc finger protein 108
chrX_-_36645359 1.474 ENSMUST00000051906.6
Akap17b
A kinase (PRKA) anchor protein 17B
chr12_+_51348370 1.456 ENSMUST00000121521.1
G2e3
G2/M-phase specific E3 ubiquitin ligase
chr5_-_86172747 1.446 ENSMUST00000039373.7
Uba6
ubiquitin-like modifier activating enzyme 6
chr9_-_7836980 1.439 ENSMUST00000054878.5
C330006D17Rik
RIKEN cDNA C330006D17 gene
chr8_-_129221950 1.438 ENSMUST00000079272.6
2610044O15Rik8
RIKEN cDNA 2610044O15 gene
chr17_+_49428359 1.435 ENSMUST00000165390.2
ENSMUST00000024797.9
ENSMUST00000173033.1
Mocs1


molybdenum cofactor synthesis 1


chr17_-_46831413 1.426 ENSMUST00000040624.5
Gltscr1l
GLTSCR1-like
chr12_+_51348265 1.411 ENSMUST00000119211.1
G2e3
G2/M-phase specific E3 ubiquitin ligase
chr4_+_47386216 1.408 ENSMUST00000107725.2
Tgfbr1
transforming growth factor, beta receptor I
chr4_-_59138983 1.402 ENSMUST00000107547.1
AI481877
expressed sequence AI481877
chr4_+_12140263 1.387 ENSMUST00000050069.2
ENSMUST00000069128.7
Rbm12b1

RNA binding motif protein 12 B1

chr17_+_94873986 1.365 ENSMUST00000108007.4
Gm20939
predicted gene, 20939
chr7_-_45370559 1.359 ENSMUST00000003971.7
Lin7b
lin-7 homolog B (C. elegans)
chr9_-_73039644 1.357 ENSMUST00000184389.1
Pigb
phosphatidylinositol glycan anchor biosynthesis, class B
chr4_-_155645408 1.338 ENSMUST00000115821.2
Gm10563
predicted gene 10563
chr5_-_138155694 1.329 ENSMUST00000132318.1
ENSMUST00000049393.8
Zfp113

zinc finger protein 113

chrY_+_818646 1.319 ENSMUST00000115894.1
Uba1y
ubiquitin-activating enzyme, Chr Y
chr11_+_105146893 1.315 ENSMUST00000100338.1
Gm10842
predicted gene 10842
chrX_-_162888426 1.313 ENSMUST00000033723.3
Syap1
synapse associated protein 1
chr7_-_7299492 1.310 ENSMUST00000000619.6
Clcn4-2
chloride channel 4-2
chr4_-_101844023 1.306 ENSMUST00000106919.1
B020004J07Rik
RIKEN cDNA B020004J07 gene
chr17_-_71460395 1.303 ENSMUST00000180522.1
Gm4707
predicted gene 4707
chr14_-_79868398 1.292 ENSMUST00000179430.1
Gm10845
predicted gene 10845
chr18_-_10610346 1.289 ENSMUST00000025142.5
Esco1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chrX_-_103623704 1.284 ENSMUST00000130063.1
ENSMUST00000125419.1
Ftx

Ftx transcript, Xist regulator (non-protein coding)

chr4_+_155812489 1.279 ENSMUST00000030944.4
Ccnl2
cyclin L2
chr1_+_85575676 1.272 ENSMUST00000178024.1
G530012D18Rik
RIKEN cDNA G530012D1 gene
chr16_+_93832121 1.269 ENSMUST00000044068.6
Morc3
microrchidia 3
chr7_-_64374071 1.260 ENSMUST00000163289.1
Fan1
FANCD2/FANCI-associated nuclease 1
chr12_-_85097080 1.254 ENSMUST00000177289.2
Prox2
prospero homeobox 2
chr9_-_89092835 1.254 ENSMUST00000167113.1
Trim43b
tripartite motif-containing 43B
chr7_+_30169861 1.243 ENSMUST00000085668.4
Gm5113
predicted gene 5113
chr5_+_138280516 1.226 ENSMUST00000048028.8
Stag3
stromal antigen 3
chr11_+_67025144 1.220 ENSMUST00000079077.5
ENSMUST00000061786.5
Tmem220

transmembrane protein 220

chr2_-_127584668 1.210 ENSMUST00000110368.2
ENSMUST00000077422.5
Zfp661

zinc finger protein 661

chr4_+_74242468 1.204 ENSMUST00000077851.3
Kdm4c
lysine (K)-specific demethylase 4C
chr2_+_140152043 1.201 ENSMUST00000104994.2
Gm17374
predicted gene, 17374
chrX_-_7907835 1.187 ENSMUST00000085330.4
Gm10491
predicted gene 10491
chr10_+_18407658 1.186 ENSMUST00000037341.7
Nhsl1
NHS-like 1
chr14_-_52279238 1.177 ENSMUST00000167116.1
ENSMUST00000100631.4
Rab2b

RAB2B, member RAS oncogene family

chr3_-_113630068 1.156 ENSMUST00000092154.3
ENSMUST00000106536.1
ENSMUST00000106535.1
Rnpc3


RNA-binding region (RNP1, RRM) containing 3


chr6_+_142345648 1.152 ENSMUST00000041852.7
Pyroxd1
pyridine nucleotide-disulphide oxidoreductase domain 1
chr5_+_47984793 1.145 ENSMUST00000170109.2
ENSMUST00000174421.1
ENSMUST00000173702.1
ENSMUST00000173107.1
Slit2



slit homolog 2 (Drosophila)



chr6_+_58833689 1.137 ENSMUST00000041401.8
Herc3
hect domain and RLD 3
chr11_-_4160286 1.133 ENSMUST00000093381.4
ENSMUST00000101626.2
Ccdc157

coiled-coil domain containing 157

chr11_-_116131073 1.131 ENSMUST00000106440.2
ENSMUST00000067632.3
Trim65

tripartite motif-containing 65

chr17_-_51831884 1.110 ENSMUST00000124222.1
Satb1
special AT-rich sequence binding protein 1
chr13_-_101692624 1.110 ENSMUST00000035532.6
Pik3r1
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)
chr10_-_127620960 1.104 ENSMUST00000121829.1
Lrp1
low density lipoprotein receptor-related protein 1
chr9_-_49798905 1.099 ENSMUST00000114476.2
Ncam1
neural cell adhesion molecule 1
chr2_+_104886318 1.091 ENSMUST00000111114.1
Ccdc73
coiled-coil domain containing 73
chr4_+_143412920 1.080 ENSMUST00000132915.1
ENSMUST00000037356.7
Pramef8

PRAME family member 8

chr16_-_91618986 1.080 ENSMUST00000143058.1
ENSMUST00000049244.8
ENSMUST00000169982.1
ENSMUST00000133731.1
Dnajc28



DnaJ (Hsp40) homolog, subfamily C, member 28



chr5_+_117133567 1.080 ENSMUST00000179276.1
ENSMUST00000092889.5
ENSMUST00000145640.1
Taok3


TAO kinase 3


chr2_-_76215363 1.049 ENSMUST00000144892.1
Pde11a
phosphodiesterase 11A
chr6_-_143100028 1.040 ENSMUST00000111758.2
ENSMUST00000171349.1
ENSMUST00000087485.4
C2cd5


C2 calcium-dependent domain containing 5


chr4_-_12087912 1.019 ENSMUST00000050686.3
Tmem67
transmembrane protein 67
chr16_+_32271468 1.017 ENSMUST00000093183.3
Smco1
single-pass membrane protein with coiled-coil domains 1
chr4_+_143413002 1.016 ENSMUST00000155157.1
Pramef8
PRAME family member 8
chr8_-_126971062 1.012 ENSMUST00000045994.6
Rbm34
RNA binding motif protein 34
chr5_-_3893907 1.009 ENSMUST00000117463.1
ENSMUST00000044746.4
Mterf

mitochondrial transcription termination factor

chr10_+_53474964 1.004 ENSMUST00000168554.1
Gm5423
predicted gene 5423
chr10_-_127620922 1.001 ENSMUST00000118455.1
Lrp1
low density lipoprotein receptor-related protein 1
chr9_+_109931458 0.994 ENSMUST00000072772.5
ENSMUST00000035055.8
Map4

microtubule-associated protein 4

chr5_+_134183998 0.989 ENSMUST00000016086.3
Gtf2ird2
GTF2I repeat domain containing 2
chr8_+_88651341 0.988 ENSMUST00000109634.2
Nod2
nucleotide-binding oligomerization domain containing 2
chr4_+_141213948 0.976 ENSMUST00000097813.2
Rsg1
REM2 and RAB-like small GTPase 1
chr13_+_112467504 0.974 ENSMUST00000183868.1
Il6st
interleukin 6 signal transducer
chr2_-_119541513 0.972 ENSMUST00000171024.1
Exd1
exonuclease 3'-5' domain containing 1
chr7_-_79386943 0.969 ENSMUST00000053718.8
ENSMUST00000179243.1
Rlbp1

retinaldehyde binding protein 1

chr10_-_62342674 0.957 ENSMUST00000143179.1
ENSMUST00000130422.1
Hk1

hexokinase 1

chr14_-_79390666 0.956 ENSMUST00000022597.7
Naa16
N(alpha)-acetyltransferase 16, NatA auxiliary subunit
chr15_+_76380492 0.953 ENSMUST00000096385.4
ENSMUST00000160728.1
ENSMUST00000162319.1
Mroh1


maestro heat-like repeat family member 1


chr6_+_65042575 0.952 ENSMUST00000031984.6
Smarcad1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr10_-_62792243 0.949 ENSMUST00000020268.5
Ccar1
cell division cycle and apoptosis regulator 1
chr7_-_44751050 0.943 ENSMUST00000126366.2
Zfp473
zinc finger protein 473
chr15_+_99295087 0.927 ENSMUST00000128352.1
ENSMUST00000145482.1
Prpf40b

PRP40 pre-mRNA processing factor 40 homolog B (yeast)

chr9_+_69397933 0.924 ENSMUST00000117610.1
ENSMUST00000145538.1
ENSMUST00000117246.1
Narg2


NMDA receptor-regulated gene 2


chr7_+_118597295 0.924 ENSMUST00000121715.1
ENSMUST00000098088.4
Tmc5

transmembrane channel-like gene family 5

chr4_-_101981049 0.923 ENSMUST00000106916.1
Gm12790
predicted gene 12790
chr17_+_24549950 0.921 ENSMUST00000035565.3
Pkd1
polycystic kidney disease 1 homolog
chr15_-_76660108 0.916 ENSMUST00000066677.8
ENSMUST00000177359.1
Cyhr1

cysteine and histidine rich 1

chr1_-_55027473 0.914 ENSMUST00000027127.7
Sf3b1
splicing factor 3b, subunit 1
chr1_-_59237093 0.914 ENSMUST00000163058.1
ENSMUST00000027178.6
Als2

amyotrophic lateral sclerosis 2 (juvenile)

chr11_+_116966731 0.913 ENSMUST00000136584.1
Mgat5b
mannoside acetylglucosaminyltransferase 5, isoenzyme B
chr14_-_59395381 0.910 ENSMUST00000166912.2
Phf11c
PHD finger protein 11C
chr16_+_20517000 0.908 ENSMUST00000171572.1
Dvl3
dishevelled 3, dsh homolog (Drosophila)
chr2_+_69722797 0.906 ENSMUST00000090858.3
Ppig
peptidyl-prolyl isomerase G (cyclophilin G)
chr7_+_45526330 0.906 ENSMUST00000120985.1
ENSMUST00000051810.8
Plekha4

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4

chr10_+_58394361 0.906 ENSMUST00000020077.4
Lims1
LIM and senescent cell antigen-like domains 1
chr14_-_20702991 0.904 ENSMUST00000180987.1
6230400D17Rik
RIKEN cDNA 6230400D17 gene
chr1_+_120006980 0.904 ENSMUST00000072886.4
Sctr
secretin receptor
chr11_-_115133981 0.903 ENSMUST00000106561.1
ENSMUST00000051264.7
ENSMUST00000106562.2
Cd300lf


CD300 antigen like family member F


chr2_-_5895319 0.897 ENSMUST00000026926.4
ENSMUST00000102981.3
Sec61a2

Sec61, alpha subunit 2 (S. cerevisiae)

chr5_+_4192367 0.896 ENSMUST00000177258.1
Gm9897
predicted gene 9897
chr9_-_15306116 0.896 ENSMUST00000178977.1
4931406C07Rik
RIKEN cDNA 4931406C07 gene
chr11_+_58867230 0.894 ENSMUST00000132570.1
2810021J22Rik
RIKEN cDNA 2810021J22 gene
chr15_+_81987835 0.893 ENSMUST00000165777.1
Xrcc6
X-ray repair complementing defective repair in Chinese hamster cells 6
chr13_-_97747373 0.890 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr5_+_110230975 0.885 ENSMUST00000031474.7
ENSMUST00000086674.5
Ankle2

ankyrin repeat and LEM domain containing 2

chr2_+_69670100 0.882 ENSMUST00000100050.3
Klhl41
kelch-like 41
chr18_-_46280820 0.879 ENSMUST00000025354.3
Pggt1b
protein geranylgeranyltransferase type I, beta subunit
chr15_+_36179530 0.871 ENSMUST00000171205.1
Spag1
sperm associated antigen 1
chr9_-_49798729 0.869 ENSMUST00000166811.2
Ncam1
neural cell adhesion molecule 1
chr5_+_34525797 0.864 ENSMUST00000125817.1
ENSMUST00000067638.7
Sh3bp2

SH3-domain binding protein 2

chr2_-_26640230 0.864 ENSMUST00000181621.1
ENSMUST00000180659.1
Snhg7

small nucleolar RNA host gene (non-protein coding) 7

chr10_-_86011833 0.864 ENSMUST00000105304.1
ENSMUST00000061699.5
Bpifc

BPI fold containing family C

chr11_+_61956779 0.859 ENSMUST00000049836.7
Specc1
sperm antigen with calponin homology and coiled-coil domains 1
chr15_+_76879232 0.858 ENSMUST00000023179.5
Zfp7
zinc finger protein 7
chr14_+_32166104 0.857 ENSMUST00000164341.1
Ncoa4
nuclear receptor coactivator 4
chr6_-_72617000 0.856 ENSMUST00000070524.4
Tgoln1
trans-golgi network protein
chr16_+_11406618 0.855 ENSMUST00000122168.1
Snx29
sorting nexin 29
chr9_-_64341145 0.854 ENSMUST00000120760.1
ENSMUST00000168844.2
Dis3l

DIS3 mitotic control homolog (S. cerevisiae)-like

chr10_+_80702649 0.851 ENSMUST00000095426.3
Izumo4
IZUMO family member 4
chr2_-_121473993 0.839 ENSMUST00000056732.3
Mfap1b
microfibrillar-associated protein 1B
chr17_+_34931253 0.837 ENSMUST00000007253.5
Neu1
neuraminidase 1
chr9_+_88581036 0.834 ENSMUST00000164661.2
Trim43a
tripartite motif-containing 43A
chr11_-_96916448 0.828 ENSMUST00000103152.4
Cdk5rap3
CDK5 regulatory subunit associated protein 3
chr11_+_51261719 0.827 ENSMUST00000130641.1
Clk4
CDC like kinase 4
chr1_-_16093286 0.818 ENSMUST00000145070.1
ENSMUST00000151004.1
4930444P10Rik

RIKEN cDNA 4930444P10 gene

chr17_-_12909912 0.812 ENSMUST00000163394.1
Pnldc1
poly(A)-specific ribonuclease (PARN)-like domain containing 1
chr4_+_11123950 0.810 ENSMUST00000142297.1
Gm11827
predicted gene 11827
chr5_-_124425907 0.809 ENSMUST00000065263.5
Sbno1
sno, strawberry notch homolog 1 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 7.8 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
1.3 6.3 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
1.0 1.0 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.9 0.9 GO:0060854 patterning of lymph vessels(GO:0060854)
0.9 3.5 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
0.8 2.4 GO:0070944 neutrophil mediated killing of bacterium(GO:0070944)
0.8 2.3 GO:1902256 endocardial cushion fusion(GO:0003274) apoptotic process involved in outflow tract morphogenesis(GO:0003275) atrial septum primum morphogenesis(GO:0003289) positive regulation of catagen(GO:0051795) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.8 3.0 GO:1990743 protein sialylation(GO:1990743)
0.7 3.4 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.7 2.0 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.6 1.8 GO:0032650 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) interleukin-1 alpha secretion(GO:0050703) regulation of bleb assembly(GO:1904170)
0.6 1.7 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.6 1.7 GO:0030210 heparin biosynthetic process(GO:0030210)
0.5 2.2 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.5 3.7 GO:1900223 positive regulation of beta-amyloid clearance(GO:1900223)
0.5 1.6 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.5 3.0 GO:0002317 plasma cell differentiation(GO:0002317)
0.5 1.4 GO:1905223 epicardium morphogenesis(GO:1905223)
0.5 1.9 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.4 1.1 GO:0021972 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.4 1.1 GO:0042275 error-free postreplication DNA repair(GO:0042275)
0.3 1.6 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.3 1.0 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165) regulation of interleukin-6-mediated signaling pathway(GO:0070103) negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
0.3 2.3 GO:0044838 germ-line stem cell population maintenance(GO:0030718) cell quiescence(GO:0044838)
0.3 1.5 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.3 0.9 GO:2000427 interleukin-4-mediated signaling pathway(GO:0035771) response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963) positive regulation of apoptotic cell clearance(GO:2000427)
0.3 0.9 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.3 0.9 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.3 1.4 GO:0021764 amygdala development(GO:0021764)
0.3 1.4 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.3 1.4 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.3 1.3 GO:0034421 post-translational protein acetylation(GO:0034421)
0.2 2.2 GO:0060613 fat pad development(GO:0060613)
0.2 0.7 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.2 0.7 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.2 0.7 GO:0016095 polyprenol catabolic process(GO:0016095) terpenoid catabolic process(GO:0016115) primary alcohol catabolic process(GO:0034310)
0.2 0.9 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.2 1.3 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.2 0.6 GO:0006667 sphinganine metabolic process(GO:0006667) regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.2 1.0 GO:0051012 microtubule sliding(GO:0051012)
0.2 0.6 GO:0090646 RNA 5'-end processing(GO:0000966) mitochondrial tRNA processing(GO:0090646)
0.2 1.0 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.2 2.9 GO:0097502 mannosylation(GO:0097502)
0.2 1.5 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.2 0.7 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.2 0.7 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.2 0.5 GO:0018094 protein polyglycylation(GO:0018094)
0.2 0.8 GO:0006689 ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.2 0.8 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.2 1.0 GO:0034587 piRNA metabolic process(GO:0034587)
0.2 0.8 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.2 0.5 GO:0016237 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) suppression by virus of host autophagy(GO:0039521) negative regulation of sphingolipid biosynthesis involved in cellular sphingolipid homeostasis(GO:0090157)
0.2 0.9 GO:1904953 Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904953)
0.2 3.6 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.6 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 0.7 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.1 0.6 GO:0002677 negative regulation of chronic inflammatory response(GO:0002677)
0.1 0.4 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.6 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 0.4 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.1 1.0 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 1.0 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.4 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.1 1.0 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 1.3 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 1.0 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 0.3 GO:0035547 interferon-beta secretion(GO:0035546) regulation of interferon-beta secretion(GO:0035547) positive regulation of interferon-beta secretion(GO:0035549)
0.1 0.4 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.1 2.1 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.1 1.2 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.9 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 1.2 GO:0010459 negative regulation of heart rate(GO:0010459)
0.1 0.6 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 2.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 0.3 GO:0046874 quinolinate metabolic process(GO:0046874)
0.1 1.1 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.1 1.0 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.1 0.3 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 1.2 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 2.2 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.1 1.1 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.1 0.3 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 0.3 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.1 0.8 GO:0071569 protein ufmylation(GO:0071569)
0.1 0.5 GO:0048539 bone marrow development(GO:0048539)
0.1 0.3 GO:1900365 cytoplasmic translational elongation(GO:0002182) thermoception(GO:0050955) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248) positive regulation of mRNA polyadenylation(GO:1900365)
0.1 0.2 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 1.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 1.4 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.4 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 1.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.1 0.5 GO:0003383 apical constriction(GO:0003383)
0.1 1.0 GO:0070933 histone H4 deacetylation(GO:0070933)
0.1 0.5 GO:0033227 dsRNA transport(GO:0033227)
0.1 1.1 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 1.2 GO:0070544 histone H3-K9 demethylation(GO:0033169) histone H3-K36 demethylation(GO:0070544)
0.1 0.9 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.1 1.3 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.1 0.5 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.1 1.2 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 0.5 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.3 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.5 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.1 1.0 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 1.6 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.1 0.7 GO:0010447 response to acidic pH(GO:0010447)
0.1 2.6 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.1 2.3 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.1 4.8 GO:0001824 blastocyst development(GO:0001824)
0.1 0.3 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.7 GO:0045056 transcytosis(GO:0045056)
0.0 0.2 GO:0010813 neuropeptide catabolic process(GO:0010813) dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.0 0.3 GO:0036337 Fas signaling pathway(GO:0036337)
0.0 0.1 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 1.1 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.8 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.7 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.5 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 2.0 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 1.8 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 0.1 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.4 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 1.3 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.5 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.0 0.1 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.1 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 2.0 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.2 GO:0021940 positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.0 0.5 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.3 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.0 0.6 GO:0051642 centrosome localization(GO:0051642)
0.0 0.1 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.4 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0 0.2 GO:0009644 response to high light intensity(GO:0009644)
0.0 0.1 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.5 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 0.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.7 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.4 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.5 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.0 0.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.1 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 1.0 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.9 GO:0030819 positive regulation of cAMP biosynthetic process(GO:0030819)
0.0 0.6 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.6 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.5 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.3 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.3 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.8 GO:0007338 single fertilization(GO:0007338)
0.0 0.2 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:0006415 translational termination(GO:0006415)
0.0 0.2 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 1.1 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.1 GO:0035878 nail development(GO:0035878)
0.0 0.1 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.0 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.0 1.9 GO:0046578 regulation of Ras protein signal transduction(GO:0046578)
0.0 0.6 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.0 0.1 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 0.1 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:0000802 transverse filament(GO:0000802)
0.4 1.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.3 1.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.2 0.9 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.2 1.4 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.2 0.7 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.2 0.9 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.2 1.7 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.2 0.5 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.2 0.6 GO:0035339 SPOTS complex(GO:0035339)
0.2 1.5 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.1 2.0 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 1.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.3 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 0.4 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 3.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 2.2 GO:0016580 Sin3 complex(GO:0016580)
0.1 0.8 GO:0070652 HAUS complex(GO:0070652)
0.1 2.4 GO:0071010 prespliceosome(GO:0071010)
0.1 1.2 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 0.7 GO:0031415 NatA complex(GO:0031415)
0.1 0.9 GO:1990909 Wnt signalosome(GO:1990909)
0.1 1.6 GO:0042588 zymogen granule(GO:0042588)
0.1 1.2 GO:0044754 autolysosome(GO:0044754)
0.1 0.8 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.9 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.5 GO:0070847 core mediator complex(GO:0070847)
0.1 1.1 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 0.6 GO:0002177 manchette(GO:0002177)
0.1 1.0 GO:0017119 Golgi transport complex(GO:0017119)
0.1 1.6 GO:0001891 phagocytic cup(GO:0001891)
0.1 1.0 GO:0036038 MKS complex(GO:0036038)
0.1 0.4 GO:0089701 U2AF(GO:0089701)
0.1 0.5 GO:0033269 internode region of axon(GO:0033269)
0.1 1.0 GO:0005682 U5 snRNP(GO:0005682)
0.1 0.2 GO:0097447 dendritic tree(GO:0097447)
0.1 0.8 GO:0033202 DNA helicase complex(GO:0033202)
0.1 1.1 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 3.0 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 1.0 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.5 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.7 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.3 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.6 GO:0001741 XY body(GO:0001741)
0.0 1.2 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.5 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.4 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.3 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 0.9 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.6 GO:0002102 podosome(GO:0002102)
0.0 0.9 GO:0031430 M band(GO:0031430)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.3 GO:0090543 Flemming body(GO:0090543)
0.0 1.0 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.2 GO:0097208 alveolar lamellar body(GO:0097208)
0.0 2.3 GO:0016605 PML body(GO:0016605)
0.0 1.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 1.0 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.3 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 1.9 GO:0005604 basement membrane(GO:0005604)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.6 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.6 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.5 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.1 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 3.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.0 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 7.8 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
1.1 6.3 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.7 2.1 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.6 2.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.6 2.8 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.5 1.6 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.5 1.6 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.5 1.5 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.5 1.5 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.5 3.0 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.4 1.6 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.3 1.0 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924)
0.3 1.3 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.3 1.1 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.3 2.2 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.2 1.0 GO:0042834 peptidoglycan binding(GO:0042834)
0.2 0.7 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.2 1.4 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.2 1.4 GO:0097016 L27 domain binding(GO:0097016)
0.2 2.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 0.6 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.2 1.0 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 1.1 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.2 0.9 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.2 0.5 GO:0070736 protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736)
0.2 1.0 GO:0019841 retinol binding(GO:0019841)
0.2 0.5 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.2 0.8 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.2 0.5 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.2 0.5 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.2 0.9 GO:0097001 ceramide binding(GO:0097001)
0.1 1.0 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 0.7 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.1 1.1 GO:0048495 GTPase inhibitor activity(GO:0005095) Roundabout binding(GO:0048495)
0.1 0.6 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 3.3 GO:0042287 MHC protein binding(GO:0042287)
0.1 0.5 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 0.7 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1 3.6 GO:0070064 proline-rich region binding(GO:0070064)
0.1 2.9 GO:0000030 mannosyltransferase activity(GO:0000030)
0.1 2.1 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 0.5 GO:0050436 microfibril binding(GO:0050436)
0.1 0.6 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.1 1.2 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.1 2.0 GO:0030275 LRR domain binding(GO:0030275)
0.1 0.3 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.1 0.8 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 0.7 GO:0005131 growth hormone receptor binding(GO:0005131)
0.1 0.6 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.9 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 1.9 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 1.6 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 1.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.7 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 1.7 GO:0008373 sialyltransferase activity(GO:0008373)
0.1 0.2 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.7 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 0.6 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 0.7 GO:0043394 proteoglycan binding(GO:0043394)
0.1 1.9 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 1.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454) histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.2 GO:0030984 kininogen binding(GO:0030984)
0.1 0.2 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 0.8 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 1.0 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.7 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 2.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 1.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.0 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0036004 GAF domain binding(GO:0036004)
0.0 0.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.3 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 1.1 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.5 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.7 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.4 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 1.0 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 0.4 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 1.7 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.4 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.5 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.6 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 2.5 GO:0005178 integrin binding(GO:0005178)
0.0 0.1 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 1.3 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.0 1.5 GO:0002039 p53 binding(GO:0002039)
0.0 0.7 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.8 GO:0005507 copper ion binding(GO:0005507)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 4.3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.8 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 1.1 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.7 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.7 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 1.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.5 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.4 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.4 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 10.1 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 1.4 GO:0017124 SH3 domain binding(GO:0017124)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.3 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 0.7 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.1 4.2 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.1 2.6 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.1 1.1 PID_IL5_PATHWAY IL5-mediated signaling events
0.1 0.9 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.1 1.0 PID_IL27_PATHWAY IL27-mediated signaling events
0.0 5.9 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.5 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 2.2 PID_ERBB4_PATHWAY ErbB4 signaling events
0.0 1.7 PID_ARF6_PATHWAY Arf6 signaling events
0.0 1.1 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 1.0 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.0 0.7 ST_GA12_PATHWAY G alpha 12 Pathway
0.0 0.8 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.3 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.8 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.5 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 1.6 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.3 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.0 0.9 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.5 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 0.9 PID_TCR_PATHWAY TCR signaling in naïve CD4+ T cells
0.0 1.0 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.6 PID_FOXO_PATHWAY FoxO family signaling
0.0 1.8 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.8 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.2 0.7 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.2 3.0 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.2 1.8 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.5 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.1 1.1 REACTOME_ACYL_CHAIN_REMODELLING_OF_PI Genes involved in Acyl chain remodelling of PI
0.1 3.0 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 2.9 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 2.2 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.0 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.1 1.9 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 5.8 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 8.2 REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.1 1.6 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 0.6 REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 1.1 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 3.6 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.1 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 1.8 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 0.9 REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS Genes involved in Glucagon-type ligand receptors
0.1 4.4 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.1 0.9 REACTOME_INTEGRATION_OF_PROVIRUS Genes involved in Integration of provirus
0.0 0.6 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.0 REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 1.6 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.0 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 1.0 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.8 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 2.5 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.8 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.0 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.0 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.8 REACTOME_G_ALPHA1213_SIGNALLING_EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.1 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.6 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.0 2.3 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.4 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.5 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.1 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.1 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis