Motif ID: Foxa2_Foxa1

Z-value: 1.249

Transcription factors associated with Foxa2_Foxa1:

Gene SymbolEntrez IDGene Name
Foxa1 ENSMUSG00000035451.6 Foxa1
Foxa2 ENSMUSG00000037025.5 Foxa2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxa2mm10_v2_chr2_-_148045891_1480459480.287.2e-02Click!
Foxa1mm10_v2_chr12_-_57546121_575461410.261.0e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Foxa2_Foxa1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_-_60177357 16.021 ENSMUST00000065086.4
Gas1
growth arrest specific 1
chr4_-_58499398 13.766 ENSMUST00000107570.1
Lpar1
lysophosphatidic acid receptor 1
chr17_-_70851710 10.613 ENSMUST00000166395.2
Tgif1
TGFB-induced factor homeobox 1
chr6_+_5390387 9.791 ENSMUST00000183358.1
Asb4
ankyrin repeat and SOCS box-containing 4
chr12_-_56535047 8.539 ENSMUST00000178477.2
Nkx2-1
NK2 homeobox 1
chr16_-_22439719 8.157 ENSMUST00000079601.6
Etv5
ets variant gene 5
chr2_+_25180737 8.065 ENSMUST00000104999.2
Nrarp
Notch-regulated ankyrin repeat protein
chr14_-_48662740 7.878 ENSMUST00000122009.1
Otx2
orthodenticle homolog 2 (Drosophila)
chr10_-_93310963 6.053 ENSMUST00000151153.1
Elk3
ELK3, member of ETS oncogene family
chr14_+_73237891 5.892 ENSMUST00000044405.6
Lpar6
lysophosphatidic acid receptor 6
chr12_-_99883429 5.732 ENSMUST00000046485.3
Efcab11
EF-hand calcium binding domain 11
chr9_+_78615501 5.704 ENSMUST00000093812.4
Cd109
CD109 antigen
chr6_+_15185203 5.558 ENSMUST00000154448.1
Foxp2
forkhead box P2
chr5_+_75152274 5.539 ENSMUST00000000476.8
Pdgfra
platelet derived growth factor receptor, alpha polypeptide
chr10_-_93311073 5.477 ENSMUST00000008542.5
Elk3
ELK3, member of ETS oncogene family
chr3_-_145649970 5.192 ENSMUST00000029846.3
Cyr61
cysteine rich protein 61
chr4_+_11191726 5.190 ENSMUST00000029866.9
ENSMUST00000108324.3
Ccne2

cyclin E2

chr18_-_60501983 5.156 ENSMUST00000042710.6
Smim3
small integral membrane protein 3
chr2_-_172940299 4.975 ENSMUST00000009143.7
Bmp7
bone morphogenetic protein 7
chr2_+_73271925 4.516 ENSMUST00000090813.5
Sp9
trans-acting transcription factor 9
chr7_+_67655414 4.515 ENSMUST00000107470.1
Ttc23
tetratricopeptide repeat domain 23
chr17_+_85613432 4.397 ENSMUST00000176081.1
Six3
sine oculis-related homeobox 3
chr2_+_14873656 4.266 ENSMUST00000114718.1
ENSMUST00000114719.1
Cacnb2

calcium channel, voltage-dependent, beta 2 subunit

chr6_+_8948608 4.136 ENSMUST00000160300.1
Nxph1
neurexophilin 1
chr1_-_138619687 3.934 ENSMUST00000027642.2
Nek7
NIMA (never in mitosis gene a)-related expressed kinase 7
chr4_-_82885148 3.841 ENSMUST00000048430.3
Cer1
cerberus 1 homolog (Xenopus laevis)
chr11_-_68386821 3.826 ENSMUST00000021284.3
Ntn1
netrin 1
chr16_+_91269759 3.710 ENSMUST00000056882.5
Olig1
oligodendrocyte transcription factor 1
chr2_-_104742802 3.583 ENSMUST00000028595.7
Depdc7
DEP domain containing 7
chr1_+_156838915 3.560 ENSMUST00000111720.1
Angptl1
angiopoietin-like 1
chr17_+_29090969 3.538 ENSMUST00000119901.1
Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
chr2_-_51972990 3.472 ENSMUST00000145481.1
ENSMUST00000112705.2
Nmi

N-myc (and STAT) interactor

chr4_-_55532453 3.402 ENSMUST00000132746.1
ENSMUST00000107619.2
Klf4

Kruppel-like factor 4 (gut)

chr4_+_11191354 3.339 ENSMUST00000170901.1
Ccne2
cyclin E2
chr13_-_83729544 3.247 ENSMUST00000181705.1
Gm26803
predicted gene, 26803
chr14_+_48120841 3.231 ENSMUST00000073150.4
Peli2
pellino 2
chr9_-_107668967 3.135 ENSMUST00000177567.1
Slc38a3
solute carrier family 38, member 3
chr13_-_74807913 3.129 ENSMUST00000065629.4
Cast
calpastatin
chr10_+_88091070 2.914 ENSMUST00000048621.7
Pmch
pro-melanin-concentrating hormone
chr1_+_12718496 2.883 ENSMUST00000088585.3
Sulf1
sulfatase 1
chr19_+_55741810 2.702 ENSMUST00000111657.3
ENSMUST00000061496.9
ENSMUST00000041717.7
ENSMUST00000111662.4
Tcf7l2



transcription factor 7 like 2, T cell specific, HMG box



chr1_-_156034826 2.701 ENSMUST00000141878.1
ENSMUST00000123705.1
Tor1aip1

torsin A interacting protein 1

chr18_-_84086379 2.688 ENSMUST00000060303.8
Tshz1
teashirt zinc finger family member 1
chr2_-_70825726 2.660 ENSMUST00000038584.8
Tlk1
tousled-like kinase 1
chr10_+_111506286 2.648 ENSMUST00000164773.1
Phlda1
pleckstrin homology-like domain, family A, member 1
chr2_-_51973219 2.639 ENSMUST00000028314.2
Nmi
N-myc (and STAT) interactor
chr12_-_56536895 2.555 ENSMUST00000001536.8
Nkx2-1
NK2 homeobox 1
chr15_-_55548164 2.549 ENSMUST00000165356.1
Mrpl13
mitochondrial ribosomal protein L13
chr7_+_113765998 2.544 ENSMUST00000046687.9
Spon1
spondin 1, (f-spondin) extracellular matrix protein
chr4_+_105790534 2.502 ENSMUST00000185012.1
Gm12728
predicted gene 12728
chr6_-_3494587 2.492 ENSMUST00000049985.8
Hepacam2
HEPACAM family member 2
chr3_-_46447939 2.418 ENSMUST00000166505.1
Pabpc4l
poly(A) binding protein, cytoplasmic 4-like
chr3_-_101836223 2.379 ENSMUST00000061831.4
Mab21l3
mab-21-like 3 (C. elegans)
chr10_-_128180265 2.374 ENSMUST00000099139.1
Rbms2
RNA binding motif, single stranded interacting protein 2
chr5_-_51567717 2.367 ENSMUST00000127135.1
ENSMUST00000151104.1
Ppargc1a

peroxisome proliferative activated receptor, gamma, coactivator 1 alpha

chr9_+_74848437 2.332 ENSMUST00000161862.1
ENSMUST00000162089.1
ENSMUST00000160017.1
ENSMUST00000160950.1
Gm16551


Gm20649
predicted gene 16551


predicted gene 20649
chr5_-_138170992 2.276 ENSMUST00000139983.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr5_-_138171248 2.236 ENSMUST00000153867.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr19_+_37376359 2.212 ENSMUST00000012587.3
Kif11
kinesin family member 11
chr6_+_147032528 2.196 ENSMUST00000036194.4
Rep15
RAB15 effector protein
chrX_+_106920618 2.187 ENSMUST00000060576.7
Lpar4
lysophosphatidic acid receptor 4
chr10_-_13388753 2.180 ENSMUST00000105546.1
Phactr2
phosphatase and actin regulator 2
chr12_+_71016658 2.167 ENSMUST00000125125.1
Arid4a
AT rich interactive domain 4A (RBP1-like)
chr4_+_98546710 2.036 ENSMUST00000102792.3
Inadl
InaD-like (Drosophila)
chr10_-_13388830 2.035 ENSMUST00000079698.5
Phactr2
phosphatase and actin regulator 2
chrX_+_56786527 2.009 ENSMUST00000144600.1
Fhl1
four and a half LIM domains 1
chr7_-_73375722 1.978 ENSMUST00000181299.1
A730056A06Rik
RIKEN cDNA A730056A06 gene
chrX_+_96455359 1.977 ENSMUST00000033553.7
Heph
hephaestin
chr11_-_68386974 1.974 ENSMUST00000135141.1
Ntn1
netrin 1
chr2_+_110597298 1.931 ENSMUST00000045972.6
ENSMUST00000111026.2
Slc5a12

solute carrier family 5 (sodium/glucose cotransporter), member 12

chr4_+_98546919 1.931 ENSMUST00000030290.7
Inadl
InaD-like (Drosophila)
chr6_+_14901344 1.894 ENSMUST00000115477.1
Foxp2
forkhead box P2
chr5_+_92809372 1.882 ENSMUST00000113054.2
Shroom3
shroom family member 3
chr13_+_49582745 1.878 ENSMUST00000065494.7
Omd
osteomodulin
chr8_+_127064022 1.841 ENSMUST00000160272.1
ENSMUST00000079777.5
ENSMUST00000162907.1
Pard3


par-3 (partitioning defective 3) homolog (C. elegans)


chr12_+_38781093 1.825 ENSMUST00000161513.1
Etv1
ets variant gene 1
chr4_+_11579647 1.821 ENSMUST00000180239.1
Fsbp
fibrinogen silencer binding protein
chr10_-_21160925 1.677 ENSMUST00000020158.6
Myb
myeloblastosis oncogene
chr13_+_23531044 1.675 ENSMUST00000102972.3
Hist1h4h
histone cluster 1, H4h
chr7_+_113766119 1.674 ENSMUST00000084696.4
Spon1
spondin 1, (f-spondin) extracellular matrix protein
chr5_+_16553488 1.670 ENSMUST00000030683.3
Hgf
hepatocyte growth factor
chr12_+_38780817 1.613 ENSMUST00000160856.1
Etv1
ets variant gene 1
chr14_+_46832127 1.594 ENSMUST00000068532.8
Cgrrf1
cell growth regulator with ring finger domain 1
chr3_+_134236483 1.590 ENSMUST00000181904.1
ENSMUST00000053048.9
Cxxc4

CXXC finger 4

chrX_+_169685191 1.531 ENSMUST00000112104.1
ENSMUST00000112107.1
Mid1

midline 1

chr13_+_8202885 1.498 ENSMUST00000139438.1
ENSMUST00000135574.1
Adarb2

adenosine deaminase, RNA-specific, B2

chr9_-_83146601 1.447 ENSMUST00000162246.2
ENSMUST00000161796.2
Hmgn3

high mobility group nucleosomal binding domain 3

chr6_-_23248264 1.404 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr11_-_76027726 1.403 ENSMUST00000021207.6
Fam101b
family with sequence similarity 101, member B
chr7_-_65371210 1.358 ENSMUST00000102592.3
Tjp1
tight junction protein 1
chr19_+_55741884 1.317 ENSMUST00000111658.3
ENSMUST00000111654.1
Tcf7l2

transcription factor 7 like 2, T cell specific, HMG box

chr5_-_149051604 1.315 ENSMUST00000093196.4
Hmgb1
high mobility group box 1
chr13_+_65512678 1.311 ENSMUST00000081471.2
Gm10139
predicted gene 10139
chr6_-_86765807 1.310 ENSMUST00000123732.1
Anxa4
annexin A4
chr18_+_4920509 1.271 ENSMUST00000126977.1
Svil
supervillin
chr15_-_50890396 1.265 ENSMUST00000185183.1
Trps1
trichorhinophalangeal syndrome I (human)
chr16_-_22161450 1.262 ENSMUST00000115379.1
Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr1_+_59482133 1.242 ENSMUST00000114246.2
ENSMUST00000037105.6
Fzd7

frizzled homolog 7 (Drosophila)

chr18_-_88927447 1.242 ENSMUST00000147313.1
Socs6
suppressor of cytokine signaling 6
chr12_-_73113407 1.234 ENSMUST00000175693.1
Six4
sine oculis-related homeobox 4
chr7_-_100656953 1.233 ENSMUST00000107046.1
ENSMUST00000107045.1
ENSMUST00000139708.1
Plekhb1


pleckstrin homology domain containing, family B (evectins) member 1


chr2_+_181767040 1.220 ENSMUST00000108756.1
Myt1
myelin transcription factor 1
chr18_+_52465676 1.216 ENSMUST00000025406.7
Srfbp1
serum response factor binding protein 1
chr19_+_55742056 1.212 ENSMUST00000111659.2
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr2_-_113848655 1.202 ENSMUST00000102545.1
ENSMUST00000110948.1
Arhgap11a

Rho GTPase activating protein 11A

chr19_-_58455398 1.176 ENSMUST00000026076.7
Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr2_+_181767283 1.161 ENSMUST00000108757.2
Myt1
myelin transcription factor 1
chr2_+_4718145 1.154 ENSMUST00000056914.6
Bend7
BEN domain containing 7
chr1_-_183147461 1.144 ENSMUST00000171366.1
Disp1
dispatched homolog 1 (Drosophila)
chrX_+_150594420 1.142 ENSMUST00000112713.2
Pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr10_+_128909866 1.133 ENSMUST00000026407.7
Cd63
CD63 antigen
chr2_+_9882622 1.116 ENSMUST00000114919.1
4930412O13Rik
RIKEN cDNA 4930412O13 gene
chr11_+_70432627 1.086 ENSMUST00000084954.6
ENSMUST00000108568.3
ENSMUST00000079056.2
ENSMUST00000102564.4
ENSMUST00000124943.1
ENSMUST00000150076.1
ENSMUST00000102563.1
Arrb2






arrestin, beta 2






chr19_+_5041337 1.054 ENSMUST00000116567.2
Brms1
breast cancer metastasis-suppressor 1
chr12_+_76370266 1.042 ENSMUST00000042779.3
Zbtb1
zinc finger and BTB domain containing 1
chr4_-_103215147 1.015 ENSMUST00000150285.1
Slc35d1
solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1
chr4_+_140701466 1.008 ENSMUST00000038893.5
ENSMUST00000138808.1
Rcc2

regulator of chromosome condensation 2

chr18_-_62756275 1.001 ENSMUST00000067450.1
ENSMUST00000048109.5
2700046A07Rik

RIKEN cDNA 2700046A07 gene

chr15_-_50882806 0.995 ENSMUST00000184885.1
Trps1
trichorhinophalangeal syndrome I (human)
chr11_-_49712674 0.991 ENSMUST00000020624.6
ENSMUST00000145353.1
Cnot6

CCR4-NOT transcription complex, subunit 6

chr2_-_154569720 0.986 ENSMUST00000000894.5
E2f1
E2F transcription factor 1
chr2_+_52072823 0.985 ENSMUST00000112693.2
ENSMUST00000069794.5
Rif1

Rap1 interacting factor 1 homolog (yeast)

chr16_-_36071515 0.978 ENSMUST00000004057.7
Fam162a
family with sequence similarity 162, member A
chr7_-_109960385 0.969 ENSMUST00000106722.1
Dennd5a
DENN/MADD domain containing 5A
chr14_-_101609033 0.923 ENSMUST00000161991.1
ENSMUST00000100340.3
Tbc1d4

TBC1 domain family, member 4

chr13_+_113342548 0.898 ENSMUST00000078163.7
BC067074
cDNA sequence BC067074
chr10_+_96616998 0.890 ENSMUST00000038377.7
Btg1
B cell translocation gene 1, anti-proliferative
chr2_-_154569845 0.889 ENSMUST00000103145.4
E2f1
E2F transcription factor 1
chr7_+_140763739 0.885 ENSMUST00000026552.7
Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
chr5_-_138171216 0.876 ENSMUST00000147920.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr9_+_14784638 0.851 ENSMUST00000034405.4
Mre11a
meiotic recombination 11 homolog A (S. cerevisiae)
chr12_+_38780284 0.841 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
Etv1


ets variant gene 1


chr10_+_128908907 0.837 ENSMUST00000105229.1
Cd63
CD63 antigen
chr11_+_87699897 0.837 ENSMUST00000040089.4
Rnf43
ring finger protein 43
chr8_-_78821136 0.824 ENSMUST00000130325.1
ENSMUST00000051867.6
Lsm6

LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)

chr2_+_27676440 0.818 ENSMUST00000129514.1
Rxra
retinoid X receptor alpha
chr5_-_87482258 0.813 ENSMUST00000079811.6
ENSMUST00000144144.1
Ugt2a1

UDP glucuronosyltransferase 2 family, polypeptide A1

chr9_-_48835932 0.810 ENSMUST00000093852.3
Zbtb16
zinc finger and BTB domain containing 16
chr1_-_156034800 0.808 ENSMUST00000169241.1
Tor1aip1
torsin A interacting protein 1
chr11_+_115824029 0.800 ENSMUST00000103032.4
ENSMUST00000133250.1
ENSMUST00000177736.1
Llgl2


lethal giant larvae homolog 2 (Drosophila)


chr2_-_147186389 0.798 ENSMUST00000109970.3
ENSMUST00000067075.5
Nkx2-2

NK2 homeobox 2

chr5_-_149051300 0.797 ENSMUST00000110505.1
Hmgb1
high mobility group box 1
chr19_-_58455161 0.795 ENSMUST00000135730.1
ENSMUST00000152507.1
Gfra1

glial cell line derived neurotrophic factor family receptor alpha 1

chr18_+_86394952 0.794 ENSMUST00000058829.2
Neto1
neuropilin (NRP) and tolloid (TLL)-like 1
chr14_+_64589802 0.791 ENSMUST00000180610.1
A930011O12Rik
RIKEN cDNA A930011O12 gene
chr17_-_79896028 0.788 ENSMUST00000068282.5
ENSMUST00000112437.1
Atl2

atlastin GTPase 2

chr7_-_109960461 0.787 ENSMUST00000080437.6
Dennd5a
DENN/MADD domain containing 5A
chr12_-_56613270 0.785 ENSMUST00000072631.5
Nkx2-9
NK2 homeobox 9
chr10_-_49783259 0.784 ENSMUST00000105484.3
ENSMUST00000105486.1
ENSMUST00000079751.2
ENSMUST00000105485.1
Grik2



glutamate receptor, ionotropic, kainate 2 (beta 2)



chrX_-_104671048 0.743 ENSMUST00000042070.5
Zdhhc15
zinc finger, DHHC domain containing 15
chr14_-_121915774 0.739 ENSMUST00000055475.7
Gpr18
G protein-coupled receptor 18
chr4_+_118409331 0.719 ENSMUST00000084319.4
ENSMUST00000106384.3
ENSMUST00000126089.1
ENSMUST00000073881.1
ENSMUST00000019229.8
ENSMUST00000144577.1
Med8





mediator of RNA polymerase II transcription, subunit 8 homolog (yeast)





chr13_+_83738874 0.702 ENSMUST00000052354.4
C130071C03Rik
RIKEN cDNA C130071C03 gene
chr15_+_59648644 0.699 ENSMUST00000118228.1
Trib1
tribbles homolog 1 (Drosophila)
chr7_+_81862674 0.693 ENSMUST00000119543.1
Tm6sf1
transmembrane 6 superfamily member 1
chr3_+_131112785 0.658 ENSMUST00000098611.3
Lef1
lymphoid enhancer binding factor 1
chr16_-_59632520 0.655 ENSMUST00000118438.1
Arl6
ADP-ribosylation factor-like 6
chr18_-_47333311 0.640 ENSMUST00000126684.1
ENSMUST00000156422.1
Sema6a

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A

chr4_-_24430838 0.634 ENSMUST00000183964.1
RP23-35K5.2
RP23-35K5.2
chr19_-_58455903 0.631 ENSMUST00000131877.1
Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr9_+_14784660 0.627 ENSMUST00000115632.3
ENSMUST00000147305.1
Mre11a

meiotic recombination 11 homolog A (S. cerevisiae)

chr9_+_44072196 0.619 ENSMUST00000176671.1
Usp2
ubiquitin specific peptidase 2
chr11_-_48826500 0.609 ENSMUST00000161192.2
Gm12184
predicted gene 12184
chr14_+_55854115 0.608 ENSMUST00000168479.1
Nynrin
NYN domain and retroviral integrase containing
chr13_+_8202860 0.603 ENSMUST00000064473.6
Adarb2
adenosine deaminase, RNA-specific, B2
chr1_+_9848375 0.603 ENSMUST00000097826.4
Sgk3
serum/glucocorticoid regulated kinase 3
chr5_-_5265224 0.586 ENSMUST00000115450.1
Cdk14
cyclin-dependent kinase 14
chr7_+_30565410 0.584 ENSMUST00000043850.7
Igflr1
IGF-like family receptor 1
chr6_+_38918969 0.577 ENSMUST00000003017.6
Tbxas1
thromboxane A synthase 1, platelet
chr11_-_100146120 0.568 ENSMUST00000007317.7
Krt19
keratin 19
chr4_+_108847827 0.564 ENSMUST00000102738.2
Kti12
KTI12 homolog, chromatin associated (S. cerevisiae)
chr14_+_32599922 0.562 ENSMUST00000068938.5
Prrxl1
paired related homeobox protein-like 1
chr7_-_37773555 0.561 ENSMUST00000176534.1
Zfp536
zinc finger protein 536
chr2_+_122028544 0.558 ENSMUST00000028668.7
Eif3j1
eukaryotic translation initiation factor 3, subunit J1
chr6_+_92940572 0.553 ENSMUST00000181145.1
ENSMUST00000181840.1
9530026P05Rik

RIKEN cDNA 9530026P05 gene

chr14_+_55853997 0.549 ENSMUST00000100529.3
Nynrin
NYN domain and retroviral integrase containing
chr6_-_87851074 0.544 ENSMUST00000032138.8
ENSMUST00000113619.1
Cnbp

cellular nucleic acid binding protein

chr3_+_96219858 0.543 ENSMUST00000073115.4
Hist2h2ab
histone cluster 2, H2ab
chr13_-_66227573 0.531 ENSMUST00000167981.2
Gm10772
predicted gene 10772
chr9_-_69760924 0.529 ENSMUST00000071281.4
Foxb1
forkhead box B1
chr17_+_28858411 0.527 ENSMUST00000114737.1
ENSMUST00000056866.5
Pnpla1

patatin-like phospholipase domain containing 1

chr4_-_127970951 0.505 ENSMUST00000030614.2
CK137956
cDNA sequence CK137956
chr9_+_43744399 0.503 ENSMUST00000034510.7
Pvrl1
poliovirus receptor-related 1
chr3_-_52104891 0.502 ENSMUST00000121440.1
Maml3
mastermind like 3 (Drosophila)
chr4_+_114680769 0.492 ENSMUST00000146346.1
Gm12829
predicted gene 12829
chr15_+_59648350 0.487 ENSMUST00000067543.6
Trib1
tribbles homolog 1 (Drosophila)
chr11_+_43151599 0.479 ENSMUST00000077659.5
Atp10b
ATPase, class V, type 10B
chr17_+_7925990 0.478 ENSMUST00000036370.7
Tagap
T cell activation Rho GTPase activating protein
chr2_-_176917518 0.445 ENSMUST00000108931.2
Gm14296
predicted gene 14296
chr3_+_5218546 0.429 ENSMUST00000026284.6
Zfhx4
zinc finger homeodomain 4
chr11_+_46235460 0.429 ENSMUST00000060185.2
Fndc9
fibronectin type III domain containing 9
chr1_-_52091066 0.428 ENSMUST00000105087.1
Gm3940
predicted gene 3940
chr5_+_31613939 0.410 ENSMUST00000031024.7
Mrpl33
mitochondrial ribosomal protein L33
chr8_-_47713920 0.408 ENSMUST00000038738.5
Cdkn2aip
CDKN2A interacting protein
chr9_-_71163224 0.407 ENSMUST00000074465.2
Aqp9
aquaporin 9
chr2_+_164403194 0.403 ENSMUST00000017151.1
Rbpjl
recombination signal binding protein for immunoglobulin kappa J region-like
chr14_-_55643251 0.382 ENSMUST00000120041.1
ENSMUST00000121937.1
ENSMUST00000133707.1
ENSMUST00000002391.8
ENSMUST00000121791.1
Tm9sf1




transmembrane 9 superfamily member 1




chr10_+_14523062 0.381 ENSMUST00000096020.5
Gm10335
predicted gene 10335
chr2_+_69723071 0.376 ENSMUST00000040915.8
Ppig
peptidyl-prolyl isomerase G (cyclophilin G)
chr11_-_17008647 0.375 ENSMUST00000102881.3
Plek
pleckstrin

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 11.1 GO:0021759 globus pallidus development(GO:0021759)
3.4 13.8 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
2.0 6.1 GO:1902524 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of protein K48-linked ubiquitination(GO:1902524)
2.0 7.9 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
1.8 5.5 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
1.8 9.0 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
1.7 5.0 GO:0072076 hyaluranon cable assembly(GO:0036118) nephrogenic mesenchyme development(GO:0072076) negative regulation of glomerular mesangial cell proliferation(GO:0072125) negative regulation of glomerulus development(GO:0090194) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
1.5 4.4 GO:0097402 neuroblast migration(GO:0097402)
1.5 16.0 GO:0042473 outer ear morphogenesis(GO:0042473)
1.4 4.3 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
1.3 5.2 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
1.3 3.8 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
1.1 5.7 GO:0072675 osteoclast fusion(GO:0072675)
1.1 3.4 GO:0014738 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
1.0 2.9 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.9 2.7 GO:0060023 soft palate development(GO:0060023)
0.9 9.8 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.8 8.4 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.7 8.1 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.7 5.8 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.7 2.9 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.7 2.1 GO:0045819 plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819)
0.7 11.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.7 7.6 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.6 3.1 GO:0015817 glutamine transport(GO:0006868) histidine transport(GO:0015817) cellular response to potassium ion starvation(GO:0051365)
0.6 1.2 GO:0001705 ectoderm formation(GO:0001705)
0.6 1.2 GO:0098528 regulation of branch elongation involved in ureteric bud branching(GO:0072095) skeletal muscle fiber differentiation(GO:0098528)
0.6 2.4 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.5 5.4 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.5 8.8 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.5 1.9 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.5 1.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.4 3.5 GO:0071493 cellular response to UV-B(GO:0071493)
0.4 1.2 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.4 4.3 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.4 2.2 GO:0034773 histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.4 3.5 GO:0071763 nuclear membrane organization(GO:0071763)
0.3 3.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.3 3.5 GO:0060539 diaphragm development(GO:0060539)
0.3 1.8 GO:0003383 apical constriction(GO:0003383)
0.3 1.5 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.3 1.5 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.3 1.7 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.3 8.5 GO:0006270 DNA replication initiation(GO:0006270)
0.3 0.8 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.3 0.8 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.3 0.8 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.3 1.0 GO:0002572 pro-T cell differentiation(GO:0002572)
0.2 1.4 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.2 2.2 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.2 2.9 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.2 0.7 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.2 2.7 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.2 3.9 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.2 1.1 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.2 1.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.2 1.5 GO:0035372 protein localization to microtubule(GO:0035372)
0.2 1.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.2 1.0 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.2 0.8 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.2 0.7 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.2 0.8 GO:0006447 regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994)
0.2 0.8 GO:0052695 cellular glucuronidation(GO:0052695)
0.2 2.2 GO:0033572 transferrin transport(GO:0033572)
0.2 0.2 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.1 0.9 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 1.2 GO:0015074 DNA integration(GO:0015074)
0.1 1.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 2.0 GO:0035646 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.1 0.5 GO:0007412 axon target recognition(GO:0007412)
0.1 0.4 GO:2000334 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 0.9 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.1 1.0 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.6 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.4 GO:0010920 negative regulation of inositol phosphate biosynthetic process(GO:0010920)
0.1 2.3 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.1 1.7 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.1 0.2 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.8 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 1.8 GO:0006825 copper ion transport(GO:0006825)
0.1 0.2 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743) alveolar secondary septum development(GO:0061144)
0.1 0.6 GO:0021559 trigeminal nerve development(GO:0021559)
0.1 0.9 GO:0019369 drug metabolic process(GO:0017144) arachidonic acid metabolic process(GO:0019369)
0.1 0.4 GO:0015791 polyol transport(GO:0015791)
0.0 0.5 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.3 GO:0021830 interneuron migration from the subpallium to the cortex(GO:0021830)
0.0 0.6 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.0 2.8 GO:0048663 neuron fate commitment(GO:0048663)
0.0 1.8 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 0.2 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.8 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.3 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 2.0 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 4.5 GO:0030326 embryonic limb morphogenesis(GO:0030326) embryonic appendage morphogenesis(GO:0035113)
0.0 0.5 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.6 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 2.0 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 1.0 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.2 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 1.6 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 10.5 GO:0042060 wound healing(GO:0042060)
0.0 0.2 GO:1901072 glucosamine-containing compound catabolic process(GO:1901072)
0.0 1.3 GO:0060538 skeletal muscle organ development(GO:0060538)
0.0 0.3 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.7 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 2.5 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.9 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.0 0.3 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.2 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 1.2 GO:0050868 negative regulation of T cell activation(GO:0050868)
0.0 0.1 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.2 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.6 GO:0060706 cell differentiation involved in embryonic placenta development(GO:0060706)
0.0 0.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.3 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.8 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.3 GO:0030282 bone mineralization(GO:0030282)
0.0 0.3 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.6 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 8.5 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
2.0 9.8 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
1.2 3.5 GO:0070557 PCNA-p21 complex(GO:0070557)
0.6 5.2 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.5 2.0 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.5 15.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.4 4.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.4 1.1 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.4 1.9 GO:0035189 Rb-E2F complex(GO:0035189)
0.4 5.4 GO:0042555 MCM complex(GO:0042555)
0.3 0.7 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.2 1.5 GO:0030870 Mre11 complex(GO:0030870)
0.2 1.8 GO:0033269 internode region of axon(GO:0033269)
0.1 1.0 GO:0001940 male pronucleus(GO:0001940)
0.1 5.8 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 0.8 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 13.8 GO:0043198 dendritic shaft(GO:0043198)
0.1 1.0 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.6 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 0.6 GO:1990357 terminal web(GO:1990357)
0.1 0.4 GO:0001652 granular component(GO:0001652)
0.1 1.0 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 0.8 GO:0005688 U6 snRNP(GO:0005688)
0.1 6.7 GO:0031225 anchored component of membrane(GO:0031225)
0.1 5.5 GO:0005902 microvillus(GO:0005902)
0.1 0.3 GO:0044292 dendrite terminus(GO:0044292)
0.1 3.0 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 1.7 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 1.8 GO:0030904 retromer complex(GO:0030904)
0.0 1.1 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 1.9 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.8 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 0.2 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 3.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.0 GO:0016592 mediator complex(GO:0016592)
0.0 3.4 GO:0005604 basement membrane(GO:0005604)
0.0 0.6 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 1.2 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 13.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.2 GO:0030686 90S preribosome(GO:0030686)
0.0 1.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 9.7 GO:0031012 extracellular matrix(GO:0031012)
0.0 1.8 GO:0030496 midbody(GO:0030496)
0.0 0.4 GO:0032587 ruffle membrane(GO:0032587)
0.0 5.1 GO:0030426 growth cone(GO:0030426)
0.0 1.2 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 5.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 2.8 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.6 GO:0031526 brush border membrane(GO:0031526)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)
0.0 0.5 GO:0000786 nucleosome(GO:0000786)
0.0 0.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 2.8 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.5 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.5 GO:0005811 lipid particle(GO:0005811)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 21.8 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
2.9 11.5 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
1.3 3.8 GO:0016015 morphogen activity(GO:0016015)
1.2 3.5 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
1.1 5.5 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
1.0 3.1 GO:0015182 L-asparagine transmembrane transporter activity(GO:0015182)
0.9 10.8 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.9 4.3 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.7 2.1 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.7 3.4 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.6 2.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.5 5.0 GO:0070700 BMP receptor binding(GO:0070700)
0.5 10.6 GO:0070410 co-SMAD binding(GO:0070410)
0.4 1.7 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.4 1.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.4 1.8 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.3 0.9 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.3 1.9 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.3 8.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.2 6.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.2 5.0 GO:0045295 gamma-catenin binding(GO:0045295)
0.2 4.9 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.2 4.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.2 2.1 GO:0004000 adenosine deaminase activity(GO:0004000)
0.2 6.9 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.2 1.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.2 3.5 GO:0005521 lamin binding(GO:0005521)
0.1 0.8 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 0.8 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 1.0 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 2.4 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 0.4 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 1.7 GO:0042056 chemoattractant activity(GO:0042056)
0.1 1.1 GO:0015197 peptide transporter activity(GO:0015197)
0.1 0.8 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 2.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 1.2 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 2.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 1.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 2.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 1.0 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 2.1 GO:0005109 frizzled binding(GO:0005109)
0.1 2.8 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 0.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 1.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 4.6 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 1.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 1.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 5.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.2 GO:0030332 cyclin binding(GO:0030332)
0.0 0.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.3 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 2.3 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.8 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.9 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.1 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.8 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 3.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 2.9 GO:0051015 actin filament binding(GO:0051015)
0.0 0.5 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.2 GO:0044548 S100 protein binding(GO:0044548)
0.0 8.1 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 0.6 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 1.7 GO:0042393 histone binding(GO:0042393)
0.0 1.6 GO:0000975 regulatory region DNA binding(GO:0000975) transcription regulatory region DNA binding(GO:0044212)
0.0 0.6 GO:0016860 intramolecular oxidoreductase activity(GO:0016860)
0.0 0.1 GO:0001846 opsonin binding(GO:0001846)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 10.4 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.6 24.2 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.5 3.5 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.5 5.0 PID_ALK2_PATHWAY ALK2 signaling events
0.4 5.2 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.3 11.3 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 5.2 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.2 15.0 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.2 5.8 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.1 4.3 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 5.4 PID_ATR_PATHWAY ATR signaling pathway
0.1 11.2 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.1 4.5 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.1 2.4 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.1 1.1 PID_NFKAPPAB_ATYPICAL_PATHWAY Atypical NF-kappaB pathway
0.1 2.1 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.1 6.9 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 2.5 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 0.9 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.1 1.7 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.1 0.3 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.1 1.8 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.1 1.7 PID_ARF6_PATHWAY Arf6 signaling events
0.1 0.5 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 7.1 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.1 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.0 1.4 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.8 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 8.1 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.5 5.8 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.4 10.4 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.3 5.4 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.3 10.6 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2 3.4 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.2 1.8 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.2 1.4 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2 1.9 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.2 5.8 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.1 2.1 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 6.9 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.7 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.1 16.2 REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.1 1.7 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 1.5 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 2.9 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 3.5 REACTOME_G1_PHASE Genes involved in G1 Phase
0.1 4.5 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 3.3 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.8 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 1.5 REACTOME_KINESINS Genes involved in Kinesins
0.1 1.2 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.1 0.4 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.3 REACTOME_DIABETES_PATHWAYS Genes involved in Diabetes pathways
0.0 0.8 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 1.7 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.8 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 10.5 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.0 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 1.1 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.0 0.5 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.1 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 2.3 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.6 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 1.7 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.1 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.3 REACTOME_GRB2_EVENTS_IN_ERBB2_SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 0.5 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME_SIGNALING_BY_ACTIVATED_POINT_MUTANTS_OF_FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.2 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 0.5 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.0 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase