Motif ID: Sox3_Sox10
Z-value: 1.517


Transcription factors associated with Sox3_Sox10:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Sox10 | ENSMUSG00000033006.9 | Sox10 |
Sox3 | ENSMUSG00000045179.8 | Sox3 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Sox3 | mm10_v2_chrX_-_60893430_60893440 | -0.51 | 7.5e-04 | Click! |
Sox10 | mm10_v2_chr15_-_79164477_79164496 | -0.25 | 1.1e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.7 | 8.0 | GO:0042560 | 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560) |
2.3 | 6.8 | GO:0003349 | epicardium-derived cardiac endothelial cell differentiation(GO:0003349) |
1.7 | 15.2 | GO:1900034 | regulation of cellular response to heat(GO:1900034) |
1.6 | 7.9 | GO:0046684 | response to pyrethroid(GO:0046684) |
1.5 | 4.6 | GO:0032241 | positive regulation of nucleobase-containing compound transport(GO:0032241) |
1.5 | 6.0 | GO:2000795 | negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
1.5 | 4.4 | GO:2000620 | positive regulation of histone H4-K16 acetylation(GO:2000620) |
1.4 | 4.1 | GO:0014877 | response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
1.4 | 4.1 | GO:2000312 | regulation of kainate selective glutamate receptor activity(GO:2000312) |
1.3 | 18.6 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
1.3 | 4.0 | GO:2000344 | positive regulation of acrosome reaction(GO:2000344) |
1.3 | 5.3 | GO:1904529 | regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616) |
1.3 | 3.8 | GO:2000297 | negative regulation of synapse maturation(GO:2000297) |
1.3 | 5.1 | GO:0032289 | central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912) |
1.3 | 3.8 | GO:1903538 | meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538) |
1.2 | 3.7 | GO:1903976 | negative regulation of glial cell migration(GO:1903976) |
1.2 | 4.9 | GO:0099566 | regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566) |
1.2 | 9.3 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
1.0 | 5.2 | GO:0043314 | negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313) |
1.0 | 3.1 | GO:1904347 | intestine smooth muscle contraction(GO:0014827) regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) regulation of small intestine smooth muscle contraction(GO:1904347) small intestine smooth muscle contraction(GO:1990770) |
1.0 | 5.1 | GO:2001025 | positive regulation of response to drug(GO:2001025) |
1.0 | 9.0 | GO:0036371 | protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) |
1.0 | 2.9 | GO:0021649 | vestibulocochlear nerve structural organization(GO:0021649) ganglion morphogenesis(GO:0061552) dorsal root ganglion morphogenesis(GO:1904835) |
1.0 | 4.8 | GO:1902309 | negative regulation of peptidyl-serine dephosphorylation(GO:1902309) |
0.9 | 3.7 | GO:0021812 | neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812) |
0.9 | 3.6 | GO:0046898 | response to cycloheximide(GO:0046898) |
0.9 | 2.6 | GO:1990743 | protein sialylation(GO:1990743) |
0.9 | 3.4 | GO:0060316 | positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) |
0.9 | 2.6 | GO:0031161 | phosphatidylinositol catabolic process(GO:0031161) |
0.9 | 6.9 | GO:0086018 | SA node cell action potential(GO:0086015) SA node cell to atrial cardiac muscle cell signalling(GO:0086018) SA node cell to atrial cardiac muscle cell communication(GO:0086070) |
0.8 | 2.5 | GO:0038095 | positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095) |
0.8 | 4.7 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
0.8 | 3.8 | GO:2001016 | positive regulation of skeletal muscle cell differentiation(GO:2001016) |
0.8 | 2.3 | GO:0016598 | protein arginylation(GO:0016598) |
0.7 | 5.2 | GO:0005513 | detection of calcium ion(GO:0005513) |
0.7 | 2.2 | GO:0033634 | positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) |
0.7 | 6.5 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
0.7 | 4.3 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
0.7 | 3.6 | GO:0001661 | conditioned taste aversion(GO:0001661) amygdala development(GO:0021764) |
0.7 | 4.3 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
0.7 | 1.4 | GO:0021586 | pons maturation(GO:0021586) |
0.7 | 3.4 | GO:1900042 | positive regulation of interleukin-2 secretion(GO:1900042) |
0.7 | 2.0 | GO:0030827 | negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283) |
0.7 | 2.0 | GO:2000616 | negative regulation of histone H3-K9 acetylation(GO:2000616) |
0.7 | 1.3 | GO:1904339 | negative regulation of dopaminergic neuron differentiation(GO:1904339) |
0.6 | 1.9 | GO:0032650 | regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) interleukin-1 alpha secretion(GO:0050703) |
0.6 | 8.3 | GO:1901898 | negative regulation of relaxation of cardiac muscle(GO:1901898) |
0.6 | 1.9 | GO:0070428 | regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070432) |
0.6 | 3.7 | GO:0021626 | hindbrain maturation(GO:0021578) central nervous system maturation(GO:0021626) |
0.6 | 1.2 | GO:0097477 | lateral motor column neuron migration(GO:0097477) |
0.6 | 4.9 | GO:0045075 | interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075) |
0.6 | 4.2 | GO:0046103 | inosine biosynthetic process(GO:0046103) |
0.6 | 25.6 | GO:0007026 | negative regulation of microtubule depolymerization(GO:0007026) |
0.6 | 1.7 | GO:2001180 | negative regulation of interleukin-10 secretion(GO:2001180) |
0.6 | 1.7 | GO:0060708 | spongiotrophoblast differentiation(GO:0060708) |
0.5 | 2.1 | GO:1904425 | negative regulation of GTP binding(GO:1904425) |
0.5 | 1.6 | GO:0061588 | calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591) |
0.5 | 4.2 | GO:0035887 | aortic smooth muscle cell differentiation(GO:0035887) |
0.5 | 2.1 | GO:0003105 | negative regulation of glomerular filtration(GO:0003105) |
0.5 | 2.1 | GO:0010808 | positive regulation of synaptic vesicle priming(GO:0010808) |
0.5 | 5.6 | GO:0046543 | development of secondary female sexual characteristics(GO:0046543) |
0.5 | 1.5 | GO:0061341 | non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346) |
0.5 | 2.0 | GO:1904694 | negative regulation of vascular smooth muscle contraction(GO:1904694) |
0.5 | 4.4 | GO:0051152 | positive regulation of smooth muscle cell differentiation(GO:0051152) |
0.5 | 1.4 | GO:0061030 | epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) |
0.5 | 2.3 | GO:0035262 | gonad morphogenesis(GO:0035262) |
0.5 | 1.9 | GO:0035426 | extracellular matrix-cell signaling(GO:0035426) |
0.5 | 2.8 | GO:0007258 | JUN phosphorylation(GO:0007258) |
0.5 | 5.1 | GO:0014051 | gamma-aminobutyric acid secretion(GO:0014051) |
0.5 | 7.8 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclase activity(GO:0031280) |
0.5 | 0.5 | GO:2000331 | regulation of terminal button organization(GO:2000331) |
0.5 | 1.4 | GO:0097106 | postsynaptic density organization(GO:0097106) |
0.5 | 1.4 | GO:0090649 | response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) |
0.5 | 2.3 | GO:0000117 | regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117) |
0.5 | 1.4 | GO:0035574 | histone H4-K20 demethylation(GO:0035574) |
0.4 | 1.3 | GO:0002035 | brain renin-angiotensin system(GO:0002035) |
0.4 | 3.0 | GO:0030718 | germ-line stem cell population maintenance(GO:0030718) |
0.4 | 1.3 | GO:0070649 | formin-nucleated actin cable assembly(GO:0070649) |
0.4 | 1.3 | GO:0008594 | photoreceptor cell morphogenesis(GO:0008594) |
0.4 | 1.3 | GO:1904049 | negative regulation of spontaneous neurotransmitter secretion(GO:1904049) |
0.4 | 6.7 | GO:1901629 | regulation of presynaptic membrane organization(GO:1901629) |
0.4 | 1.7 | GO:0033326 | cerebrospinal fluid secretion(GO:0033326) |
0.4 | 2.9 | GO:0070494 | regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) |
0.4 | 1.2 | GO:1900039 | positive regulation of cellular response to hypoxia(GO:1900039) |
0.4 | 2.0 | GO:1904672 | regulation of somatic stem cell population maintenance(GO:1904672) |
0.4 | 1.5 | GO:0001922 | B-1 B cell homeostasis(GO:0001922) |
0.4 | 5.0 | GO:0035881 | amacrine cell differentiation(GO:0035881) |
0.4 | 1.1 | GO:0001543 | ovarian follicle rupture(GO:0001543) |
0.4 | 4.0 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
0.4 | 2.5 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
0.4 | 2.1 | GO:0042276 | error-prone translesion synthesis(GO:0042276) |
0.4 | 3.2 | GO:0034776 | response to histamine(GO:0034776) cellular response to histamine(GO:0071420) |
0.4 | 1.1 | GO:0035984 | response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984) |
0.3 | 1.4 | GO:0003357 | noradrenergic neuron differentiation(GO:0003357) |
0.3 | 1.7 | GO:0034162 | toll-like receptor 9 signaling pathway(GO:0034162) |
0.3 | 0.7 | GO:0002034 | angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998) regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) |
0.3 | 2.4 | GO:0060137 | maternal process involved in parturition(GO:0060137) |
0.3 | 1.7 | GO:0031022 | nuclear migration along microfilament(GO:0031022) |
0.3 | 1.0 | GO:0098974 | postsynaptic actin cytoskeleton organization(GO:0098974) |
0.3 | 1.0 | GO:0090285 | negative regulation of protein glycosylation in Golgi(GO:0090285) |
0.3 | 1.0 | GO:0060017 | parathyroid gland development(GO:0060017) |
0.3 | 4.2 | GO:0016191 | synaptic vesicle uncoating(GO:0016191) |
0.3 | 4.8 | GO:0006054 | N-acetylneuraminate metabolic process(GO:0006054) |
0.3 | 5.9 | GO:0022027 | interkinetic nuclear migration(GO:0022027) |
0.3 | 0.6 | GO:0021886 | hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888) |
0.3 | 1.2 | GO:0021698 | cerebellar cortex structural organization(GO:0021698) |
0.3 | 0.9 | GO:0070086 | ubiquitin-dependent endocytosis(GO:0070086) |
0.3 | 2.7 | GO:1990845 | adaptive thermogenesis(GO:1990845) |
0.3 | 1.5 | GO:1901843 | positive regulation of high voltage-gated calcium channel activity(GO:1901843) |
0.3 | 1.8 | GO:1990573 | potassium ion import across plasma membrane(GO:1990573) |
0.3 | 1.5 | GO:1900122 | positive regulation of receptor binding(GO:1900122) |
0.3 | 2.6 | GO:0016198 | axon choice point recognition(GO:0016198) |
0.3 | 1.2 | GO:0036072 | intramembranous ossification(GO:0001957) direct ossification(GO:0036072) |
0.3 | 3.7 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
0.3 | 4.5 | GO:0035414 | negative regulation of catenin import into nucleus(GO:0035414) |
0.3 | 0.6 | GO:0010643 | cell communication by chemical coupling(GO:0010643) |
0.3 | 4.2 | GO:0048875 | G-protein coupled glutamate receptor signaling pathway(GO:0007216) chemical homeostasis within a tissue(GO:0048875) |
0.3 | 2.5 | GO:0006020 | inositol metabolic process(GO:0006020) |
0.3 | 3.1 | GO:0070932 | histone H3 deacetylation(GO:0070932) |
0.3 | 1.4 | GO:0061073 | ciliary body morphogenesis(GO:0061073) |
0.3 | 3.0 | GO:2001135 | regulation of endocytic recycling(GO:2001135) |
0.3 | 0.8 | GO:1900149 | positive regulation of Schwann cell migration(GO:1900149) |
0.3 | 1.6 | GO:1903071 | positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071) |
0.3 | 4.8 | GO:0046069 | cGMP catabolic process(GO:0046069) |
0.3 | 0.8 | GO:0071929 | alpha-tubulin acetylation(GO:0071929) |
0.3 | 2.7 | GO:1900113 | negative regulation of histone H3-K9 trimethylation(GO:1900113) |
0.3 | 1.6 | GO:1902669 | positive regulation of axon guidance(GO:1902669) |
0.3 | 1.1 | GO:0001542 | ovulation from ovarian follicle(GO:0001542) positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) |
0.3 | 1.9 | GO:1904217 | regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222) |
0.3 | 0.8 | GO:0060158 | phospholipase C-activating dopamine receptor signaling pathway(GO:0060158) |
0.3 | 1.0 | GO:0009405 | pathogenesis(GO:0009405) |
0.3 | 3.9 | GO:1902260 | negative regulation of delayed rectifier potassium channel activity(GO:1902260) |
0.3 | 2.8 | GO:0043653 | mitochondrial fragmentation involved in apoptotic process(GO:0043653) |
0.3 | 1.0 | GO:0045627 | positive regulation of T-helper 1 cell differentiation(GO:0045627) |
0.3 | 1.0 | GO:0007352 | zygotic specification of dorsal/ventral axis(GO:0007352) positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224) positive regulation of mesoderm development(GO:2000382) |
0.2 | 0.5 | GO:0014848 | urinary bladder smooth muscle contraction(GO:0014832) urinary tract smooth muscle contraction(GO:0014848) |
0.2 | 3.0 | GO:0046855 | inositol phosphate dephosphorylation(GO:0046855) |
0.2 | 4.9 | GO:0030517 | negative regulation of axon extension(GO:0030517) |
0.2 | 2.2 | GO:0038180 | nerve growth factor signaling pathway(GO:0038180) |
0.2 | 1.0 | GO:1900740 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) |
0.2 | 1.2 | GO:0060178 | regulation of exocyst localization(GO:0060178) |
0.2 | 1.7 | GO:0032511 | late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511) |
0.2 | 0.7 | GO:0007525 | somatic muscle development(GO:0007525) |
0.2 | 0.7 | GO:0003245 | cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245) |
0.2 | 1.4 | GO:0018377 | N-terminal protein lipidation(GO:0006498) N-terminal protein myristoylation(GO:0006499) protein myristoylation(GO:0018377) |
0.2 | 8.3 | GO:0050919 | negative chemotaxis(GO:0050919) |
0.2 | 3.9 | GO:2001224 | positive regulation of neuron migration(GO:2001224) |
0.2 | 1.1 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
0.2 | 1.4 | GO:0060124 | positive regulation of growth hormone secretion(GO:0060124) |
0.2 | 2.5 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
0.2 | 7.7 | GO:0043551 | regulation of phosphatidylinositol 3-kinase activity(GO:0043551) |
0.2 | 0.7 | GO:0019676 | ammonia assimilation cycle(GO:0019676) |
0.2 | 0.7 | GO:0072382 | minus-end-directed vesicle transport along microtubule(GO:0072382) |
0.2 | 1.3 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
0.2 | 1.3 | GO:0070294 | renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294) |
0.2 | 2.4 | GO:2001269 | positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269) |
0.2 | 0.6 | GO:0003056 | regulation of vascular smooth muscle contraction(GO:0003056) |
0.2 | 1.1 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
0.2 | 1.1 | GO:0043696 | dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697) |
0.2 | 2.1 | GO:0061577 | calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) |
0.2 | 7.2 | GO:0051491 | positive regulation of filopodium assembly(GO:0051491) |
0.2 | 2.1 | GO:0014010 | Schwann cell proliferation(GO:0014010) |
0.2 | 1.0 | GO:0031547 | brain-derived neurotrophic factor receptor signaling pathway(GO:0031547) |
0.2 | 2.2 | GO:0033623 | regulation of integrin activation(GO:0033623) |
0.2 | 0.8 | GO:0055071 | cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071) |
0.2 | 2.6 | GO:0047497 | establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) |
0.2 | 2.2 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
0.2 | 0.4 | GO:0072385 | minus-end-directed organelle transport along microtubule(GO:0072385) |
0.2 | 0.4 | GO:1903406 | regulation of sodium:potassium-exchanging ATPase activity(GO:1903406) |
0.2 | 1.4 | GO:0015808 | L-alanine transport(GO:0015808) |
0.2 | 0.6 | GO:0036092 | phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092) |
0.2 | 0.4 | GO:0097026 | dendritic cell dendrite assembly(GO:0097026) |
0.2 | 7.7 | GO:0006376 | mRNA splice site selection(GO:0006376) |
0.2 | 0.7 | GO:0032328 | alanine transport(GO:0032328) |
0.2 | 1.5 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
0.2 | 0.5 | GO:0071550 | death-inducing signaling complex assembly(GO:0071550) |
0.2 | 0.7 | GO:0032570 | response to progesterone(GO:0032570) |
0.2 | 0.5 | GO:0061386 | closure of optic fissure(GO:0061386) |
0.2 | 0.5 | GO:0007217 | tachykinin receptor signaling pathway(GO:0007217) |
0.2 | 4.3 | GO:0010758 | regulation of macrophage chemotaxis(GO:0010758) |
0.2 | 0.4 | GO:0061144 | alveolar secondary septum development(GO:0061144) |
0.2 | 0.5 | GO:0009256 | 10-formyltetrahydrofolate metabolic process(GO:0009256) |
0.2 | 1.2 | GO:0007296 | vitellogenesis(GO:0007296) |
0.2 | 1.9 | GO:0060539 | diaphragm development(GO:0060539) |
0.2 | 1.0 | GO:0090315 | negative regulation of protein targeting to membrane(GO:0090315) |
0.2 | 0.7 | GO:0001920 | negative regulation of receptor recycling(GO:0001920) |
0.2 | 3.4 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
0.2 | 2.5 | GO:0030866 | cortical actin cytoskeleton organization(GO:0030866) |
0.2 | 0.7 | GO:1902268 | negative regulation of polyamine transmembrane transport(GO:1902268) |
0.2 | 4.6 | GO:0016578 | histone deubiquitination(GO:0016578) |
0.2 | 1.2 | GO:0090074 | negative regulation of protein homodimerization activity(GO:0090074) |
0.2 | 0.5 | GO:1900365 | cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248) positive regulation of mRNA polyadenylation(GO:1900365) |
0.2 | 0.8 | GO:0030643 | cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502) |
0.2 | 1.0 | GO:0045324 | late endosome to vacuole transport(GO:0045324) |
0.2 | 0.3 | GO:2000286 | receptor internalization involved in canonical Wnt signaling pathway(GO:2000286) |
0.2 | 1.0 | GO:0033564 | anterior/posterior axon guidance(GO:0033564) |
0.2 | 0.6 | GO:0016128 | phytosteroid metabolic process(GO:0016128) phytosteroid biosynthetic process(GO:0016129) |
0.2 | 0.5 | GO:0090063 | positive regulation of microtubule nucleation(GO:0090063) |
0.2 | 1.9 | GO:0021957 | corticospinal tract morphogenesis(GO:0021957) |
0.2 | 1.3 | GO:0061343 | cell adhesion involved in heart morphogenesis(GO:0061343) |
0.2 | 10.3 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
0.2 | 0.8 | GO:0061511 | centriole elongation(GO:0061511) |
0.1 | 1.3 | GO:0035507 | regulation of myosin-light-chain-phosphatase activity(GO:0035507) |
0.1 | 1.6 | GO:0007141 | male meiosis I(GO:0007141) |
0.1 | 0.4 | GO:0009597 | detection of virus(GO:0009597) |
0.1 | 0.4 | GO:0060478 | acrosomal vesicle exocytosis(GO:0060478) |
0.1 | 0.3 | GO:0060025 | regulation of synaptic activity(GO:0060025) |
0.1 | 2.1 | GO:0008090 | retrograde axonal transport(GO:0008090) |
0.1 | 1.8 | GO:0006044 | N-acetylglucosamine metabolic process(GO:0006044) |
0.1 | 2.3 | GO:0048240 | sperm capacitation(GO:0048240) |
0.1 | 0.8 | GO:0036438 | maintenance of lens transparency(GO:0036438) |
0.1 | 0.7 | GO:0045163 | clustering of voltage-gated potassium channels(GO:0045163) |
0.1 | 0.8 | GO:0031584 | activation of phospholipase D activity(GO:0031584) |
0.1 | 3.2 | GO:0008340 | determination of adult lifespan(GO:0008340) |
0.1 | 0.6 | GO:1902775 | mitochondrial large ribosomal subunit assembly(GO:1902775) |
0.1 | 1.0 | GO:0070544 | histone H3-K36 demethylation(GO:0070544) |
0.1 | 1.5 | GO:0016242 | negative regulation of macroautophagy(GO:0016242) |
0.1 | 0.6 | GO:0050912 | detection of chemical stimulus involved in sensory perception(GO:0050907) detection of chemical stimulus involved in sensory perception of taste(GO:0050912) |
0.1 | 0.5 | GO:0035435 | phosphate ion transmembrane transport(GO:0035435) |
0.1 | 0.7 | GO:0045654 | positive regulation of megakaryocyte differentiation(GO:0045654) |
0.1 | 18.8 | GO:0030041 | actin filament polymerization(GO:0030041) |
0.1 | 0.6 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
0.1 | 0.5 | GO:0021747 | cochlear nucleus development(GO:0021747) |
0.1 | 0.4 | GO:0019858 | cytosine metabolic process(GO:0019858) |
0.1 | 0.3 | GO:0007023 | post-chaperonin tubulin folding pathway(GO:0007023) |
0.1 | 1.1 | GO:0098887 | neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639) |
0.1 | 1.7 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
0.1 | 1.7 | GO:0071447 | cellular response to hydroperoxide(GO:0071447) |
0.1 | 1.1 | GO:1903608 | protein localization to cytoplasmic stress granule(GO:1903608) |
0.1 | 0.7 | GO:0007440 | foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617) |
0.1 | 0.3 | GO:1902951 | negative regulation of dendritic spine maintenance(GO:1902951) |
0.1 | 1.3 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
0.1 | 2.1 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
0.1 | 1.7 | GO:0006828 | manganese ion transport(GO:0006828) |
0.1 | 0.6 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
0.1 | 0.4 | GO:0044861 | protein transport into plasma membrane raft(GO:0044861) |
0.1 | 0.4 | GO:0060576 | intestinal epithelial cell development(GO:0060576) |
0.1 | 0.3 | GO:0001821 | histamine secretion(GO:0001821) histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553) |
0.1 | 13.1 | GO:0007416 | synapse assembly(GO:0007416) |
0.1 | 0.9 | GO:0045760 | positive regulation of action potential(GO:0045760) |
0.1 | 0.8 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
0.1 | 3.1 | GO:0010921 | regulation of phosphatase activity(GO:0010921) |
0.1 | 0.6 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
0.1 | 0.8 | GO:0032274 | gonadotropin secretion(GO:0032274) |
0.1 | 1.2 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
0.1 | 0.3 | GO:0034729 | histone H3-K79 methylation(GO:0034729) |
0.1 | 1.3 | GO:0030042 | actin filament depolymerization(GO:0030042) |
0.1 | 0.2 | GO:0030953 | astral microtubule organization(GO:0030953) |
0.1 | 0.3 | GO:0021998 | neural plate mediolateral regionalization(GO:0021998) mesoderm structural organization(GO:0048338) paraxial mesoderm structural organization(GO:0048352) regulation of cardiac ventricle development(GO:1904412) positive regulation of cardiac ventricle development(GO:1904414) |
0.1 | 0.6 | GO:0021937 | cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937) |
0.1 | 0.1 | GO:2001271 | negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271) |
0.1 | 0.4 | GO:0051012 | microtubule sliding(GO:0051012) negative regulation of nonmotile primary cilium assembly(GO:1902856) |
0.1 | 0.8 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
0.1 | 0.2 | GO:0045213 | neurotransmitter receptor metabolic process(GO:0045213) |
0.1 | 0.6 | GO:0015879 | carnitine transport(GO:0015879) |
0.1 | 0.3 | GO:0006868 | glutamine transport(GO:0006868) |
0.1 | 1.2 | GO:0008053 | mitochondrial fusion(GO:0008053) |
0.1 | 2.0 | GO:0019228 | neuronal action potential(GO:0019228) |
0.1 | 0.3 | GO:0043651 | lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) |
0.1 | 0.5 | GO:0045650 | negative regulation of macrophage differentiation(GO:0045650) |
0.1 | 1.3 | GO:1901385 | regulation of voltage-gated calcium channel activity(GO:1901385) |
0.1 | 7.2 | GO:0000045 | autophagosome assembly(GO:0000045) |
0.1 | 0.8 | GO:0046856 | phospholipid dephosphorylation(GO:0046839) phosphatidylinositol dephosphorylation(GO:0046856) |
0.1 | 0.6 | GO:0033169 | histone H3-K9 demethylation(GO:0033169) |
0.1 | 1.2 | GO:0002230 | positive regulation of defense response to virus by host(GO:0002230) |
0.1 | 0.2 | GO:1903334 | positive regulation of protein folding(GO:1903334) |
0.1 | 1.0 | GO:0033198 | response to ATP(GO:0033198) |
0.1 | 0.6 | GO:0061001 | regulation of dendritic spine morphogenesis(GO:0061001) |
0.1 | 5.0 | GO:0070936 | protein K48-linked ubiquitination(GO:0070936) |
0.1 | 0.4 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
0.1 | 0.4 | GO:1902414 | protein localization to cell junction(GO:1902414) |
0.1 | 1.7 | GO:0095500 | acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145) |
0.1 | 2.3 | GO:0032292 | myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292) |
0.1 | 1.1 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
0.1 | 0.4 | GO:0070164 | negative regulation of adiponectin secretion(GO:0070164) |
0.1 | 0.7 | GO:1990126 | retrograde transport, endosome to plasma membrane(GO:1990126) |
0.1 | 0.3 | GO:0030576 | Cajal body organization(GO:0030576) |
0.1 | 2.3 | GO:0007520 | myoblast fusion(GO:0007520) |
0.1 | 0.7 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
0.1 | 1.0 | GO:0032410 | negative regulation of transporter activity(GO:0032410) |
0.1 | 0.8 | GO:0014067 | negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067) |
0.1 | 0.6 | GO:0001675 | acrosome assembly(GO:0001675) |
0.1 | 0.6 | GO:0051231 | mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256) |
0.1 | 1.4 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
0.1 | 0.9 | GO:0045947 | negative regulation of translational initiation(GO:0045947) |
0.1 | 0.3 | GO:0035826 | rubidium ion transport(GO:0035826) |
0.1 | 0.7 | GO:0033005 | positive regulation of mast cell activation(GO:0033005) positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306) |
0.1 | 3.4 | GO:0002028 | regulation of sodium ion transport(GO:0002028) |
0.1 | 0.5 | GO:0036265 | RNA (guanine-N7)-methylation(GO:0036265) |
0.1 | 0.5 | GO:0033148 | positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148) |
0.1 | 8.9 | GO:0042787 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) |
0.1 | 0.5 | GO:0035280 | miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280) |
0.1 | 2.7 | GO:0050772 | positive regulation of axonogenesis(GO:0050772) |
0.1 | 1.1 | GO:0042744 | hydrogen peroxide catabolic process(GO:0042744) |
0.1 | 0.4 | GO:0099563 | modification of synaptic structure(GO:0099563) |
0.1 | 0.2 | GO:0030327 | prenylated protein catabolic process(GO:0030327) |
0.1 | 1.0 | GO:0032331 | negative regulation of chondrocyte differentiation(GO:0032331) |
0.1 | 5.3 | GO:0048813 | dendrite morphogenesis(GO:0048813) |
0.1 | 0.8 | GO:0031507 | heterochromatin assembly(GO:0031507) |
0.1 | 0.2 | GO:0042726 | flavin-containing compound metabolic process(GO:0042726) |
0.1 | 0.2 | GO:1904690 | regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690) |
0.1 | 0.9 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) |
0.1 | 0.9 | GO:0050832 | defense response to fungus(GO:0050832) |
0.1 | 0.4 | GO:0042769 | DNA damage response, detection of DNA damage(GO:0042769) |
0.1 | 0.4 | GO:0060480 | lung goblet cell differentiation(GO:0060480) regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250) |
0.1 | 1.0 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
0.1 | 0.8 | GO:0002495 | antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504) |
0.1 | 1.4 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
0.1 | 0.3 | GO:0030828 | positive regulation of cGMP biosynthetic process(GO:0030828) |
0.1 | 2.2 | GO:0043044 | ATP-dependent chromatin remodeling(GO:0043044) |
0.1 | 0.6 | GO:0046485 | ether lipid metabolic process(GO:0046485) |
0.1 | 0.8 | GO:0035721 | intraciliary retrograde transport(GO:0035721) |
0.0 | 0.5 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
0.0 | 0.2 | GO:0038032 | termination of G-protein coupled receptor signaling pathway(GO:0038032) |
0.0 | 0.5 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
0.0 | 1.2 | GO:0015813 | L-glutamate transport(GO:0015813) |
0.0 | 0.0 | GO:0098528 | skeletal muscle fiber differentiation(GO:0098528) |
0.0 | 0.8 | GO:0002437 | inflammatory response to antigenic stimulus(GO:0002437) |
0.0 | 3.0 | GO:0019882 | antigen processing and presentation(GO:0019882) |
0.0 | 0.0 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548) |
0.0 | 0.7 | GO:0015693 | magnesium ion transport(GO:0015693) |
0.0 | 0.3 | GO:0070995 | NADPH oxidation(GO:0070995) |
0.0 | 0.4 | GO:0010818 | T cell chemotaxis(GO:0010818) |
0.0 | 0.1 | GO:1904684 | negative regulation of metalloendopeptidase activity(GO:1904684) |
0.0 | 0.3 | GO:0045932 | negative regulation of muscle contraction(GO:0045932) |
0.0 | 0.4 | GO:0010878 | cholesterol storage(GO:0010878) steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435) |
0.0 | 2.4 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
0.0 | 0.7 | GO:0008209 | androgen metabolic process(GO:0008209) |
0.0 | 1.8 | GO:0016574 | histone ubiquitination(GO:0016574) |
0.0 | 0.6 | GO:1902187 | negative regulation of viral release from host cell(GO:1902187) |
0.0 | 0.1 | GO:0051580 | regulation of neurotransmitter uptake(GO:0051580) neurotransmitter reuptake(GO:0098810) |
0.0 | 0.1 | GO:0048570 | notochord morphogenesis(GO:0048570) |
0.0 | 0.2 | GO:0030035 | microspike assembly(GO:0030035) |
0.0 | 1.0 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
0.0 | 0.7 | GO:2001222 | regulation of neuron migration(GO:2001222) |
0.0 | 0.8 | GO:0046627 | negative regulation of insulin receptor signaling pathway(GO:0046627) |
0.0 | 1.8 | GO:0007286 | spermatid development(GO:0007286) |
0.0 | 0.1 | GO:0071544 | diphosphoinositol polyphosphate catabolic process(GO:0071544) |
0.0 | 0.3 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
0.0 | 2.7 | GO:0000209 | protein polyubiquitination(GO:0000209) |
0.0 | 0.2 | GO:2000672 | negative regulation of motor neuron apoptotic process(GO:2000672) |
0.0 | 0.4 | GO:1901223 | negative regulation of NIK/NF-kappaB signaling(GO:1901223) |
0.0 | 0.4 | GO:0045723 | positive regulation of fatty acid biosynthetic process(GO:0045723) |
0.0 | 0.9 | GO:0008542 | visual learning(GO:0008542) |
0.0 | 0.7 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
0.0 | 0.9 | GO:0072384 | organelle transport along microtubule(GO:0072384) |
0.0 | 0.6 | GO:0006368 | transcription elongation from RNA polymerase II promoter(GO:0006368) |
0.0 | 5.8 | GO:0006914 | autophagy(GO:0006914) |
0.0 | 1.0 | GO:0080171 | lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171) |
0.0 | 1.6 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
0.0 | 0.7 | GO:0015844 | monoamine transport(GO:0015844) |
0.0 | 0.7 | GO:1903169 | regulation of calcium ion transmembrane transport(GO:1903169) |
0.0 | 0.1 | GO:0060903 | positive regulation of meiosis I(GO:0060903) |
0.0 | 0.5 | GO:0030318 | melanocyte differentiation(GO:0030318) |
0.0 | 0.4 | GO:0016601 | Rac protein signal transduction(GO:0016601) |
0.0 | 0.2 | GO:0016082 | synaptic vesicle priming(GO:0016082) |
0.0 | 0.9 | GO:0048477 | oogenesis(GO:0048477) |
0.0 | 0.9 | GO:0042073 | intraciliary transport(GO:0042073) |
0.0 | 1.6 | GO:0006906 | vesicle fusion(GO:0006906) |
0.0 | 0.7 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
0.0 | 0.7 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
0.0 | 0.8 | GO:0001541 | ovarian follicle development(GO:0001541) |
0.0 | 0.3 | GO:0070584 | mitochondrion morphogenesis(GO:0070584) |
0.0 | 0.2 | GO:0070314 | G1 to G0 transition(GO:0070314) |
0.0 | 0.3 | GO:0042759 | long-chain fatty acid biosynthetic process(GO:0042759) |
0.0 | 0.1 | GO:1900246 | positive regulation of RIG-I signaling pathway(GO:1900246) |
0.0 | 0.6 | GO:0046513 | ceramide biosynthetic process(GO:0046513) |
0.0 | 0.8 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
0.0 | 0.1 | GO:0006285 | base-excision repair, AP site formation(GO:0006285) |
0.0 | 1.1 | GO:0050777 | negative regulation of immune response(GO:0050777) |
0.0 | 0.6 | GO:0034394 | protein localization to cell surface(GO:0034394) |
0.0 | 0.5 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
0.0 | 0.2 | GO:0050995 | negative regulation of lipid catabolic process(GO:0050995) |
0.0 | 0.4 | GO:0043153 | entrainment of circadian clock by photoperiod(GO:0043153) |
0.0 | 1.0 | GO:0006749 | glutathione metabolic process(GO:0006749) |
0.0 | 0.6 | GO:0034605 | cellular response to heat(GO:0034605) |
0.0 | 0.8 | GO:0042439 | ethanolamine-containing compound metabolic process(GO:0042439) |
0.0 | 0.3 | GO:0006308 | DNA catabolic process(GO:0006308) |
0.0 | 0.4 | GO:0031333 | negative regulation of protein complex assembly(GO:0031333) |
0.0 | 0.8 | GO:0048167 | regulation of synaptic plasticity(GO:0048167) |
0.0 | 0.3 | GO:0048013 | ephrin receptor signaling pathway(GO:0048013) |
0.0 | 0.3 | GO:0030148 | sphingolipid biosynthetic process(GO:0030148) |
0.0 | 0.0 | GO:0001865 | NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138) |
0.0 | 0.4 | GO:0044342 | type B pancreatic cell proliferation(GO:0044342) |
0.0 | 0.3 | GO:0006940 | regulation of smooth muscle contraction(GO:0006940) |
0.0 | 0.5 | GO:0006892 | post-Golgi vesicle-mediated transport(GO:0006892) |
0.0 | 0.2 | GO:2000401 | regulation of lymphocyte migration(GO:2000401) |
0.0 | 1.2 | GO:0043547 | positive regulation of GTPase activity(GO:0043547) |
0.0 | 0.2 | GO:0008214 | protein demethylation(GO:0006482) protein dealkylation(GO:0008214) |
0.0 | 3.0 | GO:0016567 | protein ubiquitination(GO:0016567) |
0.0 | 0.6 | GO:1902600 | hydrogen ion transmembrane transport(GO:1902600) |
0.0 | 0.2 | GO:0009988 | binding of sperm to zona pellucida(GO:0007339) cell-cell recognition(GO:0009988) sperm-egg recognition(GO:0035036) |
0.0 | 0.2 | GO:0030325 | adrenal gland development(GO:0030325) |
0.0 | 0.1 | GO:0048934 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
0.0 | 0.3 | GO:1904893 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
0.0 | 1.0 | GO:0007018 | microtubule-based movement(GO:0007018) |
0.0 | 0.2 | GO:0009299 | mRNA transcription(GO:0009299) |
0.0 | 0.0 | GO:0060279 | regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279) |
0.0 | 0.2 | GO:0070059 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.3 | 6.9 | GO:0002142 | stereocilia ankle link complex(GO:0002142) |
2.2 | 20.1 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
1.6 | 6.5 | GO:0044307 | dendritic branch(GO:0044307) |
1.5 | 15.4 | GO:0045298 | tubulin complex(GO:0045298) |
1.1 | 4.3 | GO:0099569 | presynaptic cytoskeleton(GO:0099569) |
0.9 | 3.7 | GO:0043259 | laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) |
0.9 | 3.6 | GO:0090537 | CERF complex(GO:0090537) |
0.8 | 12.4 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
0.8 | 2.3 | GO:0098855 | HCN channel complex(GO:0098855) |
0.7 | 2.1 | GO:0098831 | presynaptic active zone cytoplasmic component(GO:0098831) |
0.6 | 15.8 | GO:0071565 | nBAF complex(GO:0071565) |
0.6 | 6.8 | GO:0090544 | BAF-type complex(GO:0090544) |
0.6 | 3.0 | GO:0032437 | cuticular plate(GO:0032437) |
0.6 | 0.6 | GO:1902737 | dendritic filopodium(GO:1902737) |
0.5 | 2.1 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
0.5 | 2.1 | GO:0031673 | H zone(GO:0031673) |
0.5 | 4.2 | GO:0001520 | outer dense fiber(GO:0001520) |
0.5 | 20.7 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
0.5 | 1.4 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
0.5 | 2.3 | GO:0036449 | microtubule minus-end(GO:0036449) |
0.4 | 6.7 | GO:1990635 | proximal dendrite(GO:1990635) |
0.4 | 4.9 | GO:0043083 | synaptic cleft(GO:0043083) |
0.4 | 5.6 | GO:0016342 | catenin complex(GO:0016342) |
0.3 | 9.0 | GO:0031430 | M band(GO:0031430) |
0.3 | 7.9 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
0.3 | 5.7 | GO:0034704 | calcium channel complex(GO:0034704) |
0.3 | 1.0 | GO:0044308 | axonal spine(GO:0044308) |
0.3 | 3.6 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
0.3 | 3.8 | GO:0030057 | desmosome(GO:0030057) |
0.3 | 1.5 | GO:0038039 | G-protein coupled receptor heterodimeric complex(GO:0038039) |
0.3 | 2.6 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
0.3 | 4.8 | GO:0032279 | asymmetric synapse(GO:0032279) |
0.3 | 6.0 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
0.3 | 1.1 | GO:0070436 | Grb2-EGFR complex(GO:0070436) |
0.3 | 1.1 | GO:0060187 | cell pole(GO:0060187) |
0.3 | 4.6 | GO:0005865 | striated muscle thin filament(GO:0005865) |
0.3 | 3.9 | GO:1902710 | GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711) |
0.3 | 14.8 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
0.3 | 1.0 | GO:0032444 | activin responsive factor complex(GO:0032444) |
0.3 | 1.3 | GO:1990761 | growth cone lamellipodium(GO:1990761) |
0.2 | 2.4 | GO:0001739 | sex chromatin(GO:0001739) |
0.2 | 0.7 | GO:0097524 | sperm plasma membrane(GO:0097524) |
0.2 | 1.2 | GO:0044305 | calyx of Held(GO:0044305) |
0.2 | 5.3 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
0.2 | 1.9 | GO:0031315 | extrinsic component of mitochondrial outer membrane(GO:0031315) |
0.2 | 1.4 | GO:0000322 | storage vacuole(GO:0000322) |
0.2 | 2.0 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
0.2 | 2.0 | GO:0044327 | dendritic spine head(GO:0044327) |
0.2 | 11.5 | GO:0031941 | filamentous actin(GO:0031941) |
0.2 | 3.7 | GO:0000124 | SAGA complex(GO:0000124) |
0.2 | 1.7 | GO:1990909 | Wnt signalosome(GO:1990909) |
0.2 | 1.7 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
0.2 | 2.8 | GO:0031528 | microvillus membrane(GO:0031528) |
0.2 | 4.2 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
0.2 | 0.6 | GO:0002944 | cyclin K-CDK12 complex(GO:0002944) |
0.2 | 5.5 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
0.2 | 1.9 | GO:0032426 | stereocilium tip(GO:0032426) |
0.2 | 1.2 | GO:0005638 | lamin filament(GO:0005638) |
0.2 | 10.4 | GO:0005871 | kinesin complex(GO:0005871) |
0.2 | 2.0 | GO:0042581 | specific granule(GO:0042581) |
0.2 | 1.8 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
0.2 | 0.5 | GO:0031533 | mRNA cap methyltransferase complex(GO:0031533) |
0.1 | 1.0 | GO:0005884 | actin filament(GO:0005884) |
0.1 | 11.4 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
0.1 | 1.1 | GO:0097165 | nuclear stress granule(GO:0097165) |
0.1 | 0.4 | GO:0032156 | septin cytoskeleton(GO:0032156) |
0.1 | 4.5 | GO:0097440 | apical dendrite(GO:0097440) |
0.1 | 1.8 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
0.1 | 2.0 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
0.1 | 1.2 | GO:0002177 | manchette(GO:0002177) |
0.1 | 6.5 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
0.1 | 1.5 | GO:0098845 | postsynaptic endosome(GO:0098845) |
0.1 | 6.3 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
0.1 | 0.8 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
0.1 | 3.0 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
0.1 | 1.0 | GO:0042382 | paraspeckles(GO:0042382) |
0.1 | 0.7 | GO:0097227 | sperm annulus(GO:0097227) |
0.1 | 0.2 | GO:0097629 | extrinsic component of omegasome membrane(GO:0097629) |
0.1 | 0.5 | GO:0030906 | retromer, cargo-selective complex(GO:0030906) |
0.1 | 10.8 | GO:0043204 | perikaryon(GO:0043204) |
0.1 | 18.6 | GO:0001726 | ruffle(GO:0001726) |
0.1 | 3.8 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
0.1 | 0.8 | GO:0097427 | microtubule bundle(GO:0097427) |
0.1 | 0.7 | GO:0031933 | telomeric heterochromatin(GO:0031933) |
0.1 | 1.0 | GO:0000815 | ESCRT III complex(GO:0000815) |
0.1 | 3.2 | GO:0009986 | cell surface(GO:0009986) |
0.1 | 7.0 | GO:0030018 | Z disc(GO:0030018) |
0.1 | 1.0 | GO:0034464 | BBSome(GO:0034464) |
0.1 | 0.5 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
0.1 | 0.8 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
0.1 | 2.5 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
0.1 | 2.1 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
0.1 | 12.6 | GO:0030427 | site of polarized growth(GO:0030427) |
0.1 | 15.2 | GO:0045211 | postsynaptic membrane(GO:0045211) |
0.1 | 0.5 | GO:0031143 | pseudopodium(GO:0031143) |
0.1 | 1.1 | GO:0030027 | lamellipodium(GO:0030027) |
0.1 | 0.8 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
0.1 | 0.4 | GO:0070826 | paraferritin complex(GO:0070826) |
0.1 | 5.3 | GO:0005776 | autophagosome(GO:0005776) |
0.1 | 2.5 | GO:0035861 | site of double-strand break(GO:0035861) |
0.1 | 0.3 | GO:0071008 | U2-type post-mRNA release spliceosomal complex(GO:0071008) |
0.1 | 0.5 | GO:0070578 | micro-ribonucleoprotein complex(GO:0035068) RISC-loading complex(GO:0070578) |
0.1 | 0.8 | GO:0034451 | centriolar satellite(GO:0034451) |
0.1 | 4.2 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
0.1 | 1.5 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
0.1 | 0.7 | GO:0000812 | Swr1 complex(GO:0000812) |
0.1 | 4.1 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
0.1 | 1.4 | GO:0030017 | sarcomere(GO:0030017) |
0.1 | 1.0 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
0.1 | 0.7 | GO:0044666 | MLL3/4 complex(GO:0044666) |
0.1 | 0.9 | GO:0036038 | MKS complex(GO:0036038) |
0.1 | 0.3 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
0.1 | 0.2 | GO:0097058 | CRLF-CLCF1 complex(GO:0097058) |
0.1 | 7.3 | GO:0014069 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
0.1 | 1.1 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
0.1 | 0.5 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
0.0 | 0.3 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
0.0 | 0.9 | GO:0051233 | spindle midzone(GO:0051233) |
0.0 | 8.8 | GO:0097708 | cytoplasmic vesicle(GO:0031410) intracellular vesicle(GO:0097708) |
0.0 | 1.8 | GO:1990391 | DNA repair complex(GO:1990391) |
0.0 | 0.2 | GO:0048787 | presynaptic active zone membrane(GO:0048787) |
0.0 | 0.6 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
0.0 | 1.2 | GO:0008180 | COP9 signalosome(GO:0008180) |
0.0 | 0.5 | GO:0005869 | dynactin complex(GO:0005869) |
0.0 | 3.4 | GO:0055037 | recycling endosome(GO:0055037) |
0.0 | 1.0 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
0.0 | 0.9 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
0.0 | 1.4 | GO:0005801 | cis-Golgi network(GO:0005801) |
0.0 | 1.9 | GO:0001669 | acrosomal vesicle(GO:0001669) |
0.0 | 0.8 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
0.0 | 1.2 | GO:0005905 | clathrin-coated pit(GO:0005905) |
0.0 | 1.0 | GO:0043195 | terminal bouton(GO:0043195) |
0.0 | 0.2 | GO:0045180 | basal cortex(GO:0045180) |
0.0 | 0.4 | GO:0098797 | plasma membrane protein complex(GO:0098797) |
0.0 | 1.0 | GO:0035097 | histone methyltransferase complex(GO:0035097) |
0.0 | 0.2 | GO:0030175 | filopodium(GO:0030175) |
0.0 | 0.7 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
0.0 | 1.6 | GO:0031965 | nuclear membrane(GO:0031965) |
0.0 | 2.8 | GO:0001650 | fibrillar center(GO:0001650) |
0.0 | 0.2 | GO:0005642 | annulate lamellae(GO:0005642) |
0.0 | 0.1 | GO:0051286 | cell tip(GO:0051286) |
0.0 | 0.3 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
0.0 | 0.1 | GO:0001652 | granular component(GO:0001652) |
0.0 | 0.6 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
0.0 | 1.2 | GO:0005923 | bicellular tight junction(GO:0005923) |
0.0 | 0.6 | GO:0016592 | mediator complex(GO:0016592) |
0.0 | 2.8 | GO:0000139 | Golgi membrane(GO:0000139) |
0.0 | 0.6 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
0.0 | 4.4 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
0.0 | 0.2 | GO:0043596 | nuclear replication fork(GO:0043596) |
0.0 | 2.3 | GO:0005856 | cytoskeleton(GO:0005856) |
0.0 | 3.2 | GO:0005773 | vacuole(GO:0005773) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.7 | 8.0 | GO:0016155 | formyltetrahydrofolate dehydrogenase activity(GO:0016155) |
2.7 | 21.4 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
2.2 | 15.2 | GO:0099609 | microtubule lateral binding(GO:0099609) |
1.3 | 6.5 | GO:0003835 | beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835) |
1.2 | 3.6 | GO:0070615 | nucleosome-dependent ATPase activity(GO:0070615) |
1.1 | 4.3 | GO:0042328 | heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328) |
1.1 | 7.4 | GO:0046935 | 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
1.0 | 9.1 | GO:0003873 | 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) |
1.0 | 4.0 | GO:0008332 | low voltage-gated calcium channel activity(GO:0008332) |
1.0 | 4.0 | GO:0047275 | glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275) |
1.0 | 8.7 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
0.8 | 4.0 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
0.8 | 4.8 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
0.8 | 4.7 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
0.7 | 2.1 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
0.7 | 15.6 | GO:0005248 | voltage-gated sodium channel activity(GO:0005248) |
0.7 | 2.8 | GO:0016909 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
0.7 | 7.6 | GO:0031005 | filamin binding(GO:0031005) |
0.7 | 2.7 | GO:0017077 | oxidative phosphorylation uncoupler activity(GO:0017077) |
0.6 | 2.5 | GO:0000832 | inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724) |
0.6 | 4.9 | GO:0099583 | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) |
0.6 | 2.4 | GO:0005008 | hepatocyte growth factor-activated receptor activity(GO:0005008) |
0.6 | 4.2 | GO:0032795 | heterotrimeric G-protein binding(GO:0032795) |
0.6 | 1.7 | GO:0050656 | 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656) |
0.5 | 3.8 | GO:0048101 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
0.5 | 2.1 | GO:0005237 | inhibitory extracellular ligand-gated ion channel activity(GO:0005237) |
0.5 | 2.6 | GO:0052833 | inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834) |
0.5 | 7.1 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
0.5 | 4.6 | GO:0005523 | tropomyosin binding(GO:0005523) |
0.5 | 4.7 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
0.5 | 1.9 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
0.5 | 3.7 | GO:0043208 | glycosphingolipid binding(GO:0043208) |
0.5 | 1.4 | GO:0030350 | iron-responsive element binding(GO:0030350) |
0.5 | 1.4 | GO:0035575 | histone demethylase activity (H4-K20 specific)(GO:0035575) |
0.5 | 9.9 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
0.4 | 1.3 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
0.4 | 1.3 | GO:0005119 | smoothened binding(GO:0005119) |
0.4 | 2.9 | GO:0005021 | vascular endothelial growth factor-activated receptor activity(GO:0005021) |
0.4 | 4.6 | GO:0031802 | type 5 metabotropic glutamate receptor binding(GO:0031802) |
0.4 | 3.6 | GO:0051434 | BH3 domain binding(GO:0051434) |
0.4 | 1.2 | GO:0015173 | hydrogen:amino acid symporter activity(GO:0005280) aromatic amino acid transmembrane transporter activity(GO:0015173) |
0.4 | 0.4 | GO:0031697 | beta-1 adrenergic receptor binding(GO:0031697) |
0.4 | 3.1 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
0.4 | 6.1 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
0.4 | 1.8 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
0.4 | 3.6 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
0.3 | 1.4 | GO:0031800 | type 3 metabotropic glutamate receptor binding(GO:0031800) |
0.3 | 3.7 | GO:0015347 | sodium-independent organic anion transmembrane transporter activity(GO:0015347) |
0.3 | 2.0 | GO:0070699 | type II activin receptor binding(GO:0070699) |
0.3 | 1.0 | GO:0098973 | structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973) |
0.3 | 1.6 | GO:0001517 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) |
0.3 | 1.0 | GO:0071633 | dihydroceramidase activity(GO:0071633) |
0.3 | 8.3 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
0.3 | 3.5 | GO:0004017 | adenylate kinase activity(GO:0004017) |
0.3 | 4.1 | GO:0050897 | cobalt ion binding(GO:0050897) |
0.3 | 2.4 | GO:0016312 | inositol bisphosphate phosphatase activity(GO:0016312) |
0.3 | 1.1 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
0.3 | 0.9 | GO:0045127 | N-acetylglucosamine kinase activity(GO:0045127) |
0.3 | 3.6 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
0.3 | 0.8 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
0.3 | 1.3 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
0.3 | 1.1 | GO:0022851 | GABA-gated chloride ion channel activity(GO:0022851) |
0.3 | 17.6 | GO:0015459 | potassium channel regulator activity(GO:0015459) |
0.3 | 1.0 | GO:0005093 | Rab GDP-dissociation inhibitor activity(GO:0005093) |
0.3 | 2.3 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
0.3 | 3.8 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
0.3 | 1.8 | GO:0061665 | SUMO ligase activity(GO:0061665) |
0.3 | 7.3 | GO:0003785 | actin monomer binding(GO:0003785) |
0.3 | 6.0 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
0.2 | 1.5 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
0.2 | 4.4 | GO:0031489 | myosin V binding(GO:0031489) |
0.2 | 3.6 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
0.2 | 0.7 | GO:0008504 | monoamine transmembrane transporter activity(GO:0008504) |
0.2 | 3.7 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
0.2 | 56.5 | GO:0008017 | microtubule binding(GO:0008017) |
0.2 | 4.3 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.2 | 0.7 | GO:0035650 | AP-1 adaptor complex binding(GO:0035650) |
0.2 | 0.7 | GO:0016880 | acid-ammonia (or amide) ligase activity(GO:0016880) |
0.2 | 2.3 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
0.2 | 0.6 | GO:0008527 | taste receptor activity(GO:0008527) |
0.2 | 0.8 | GO:0047389 | glycerophosphocholine phosphodiesterase activity(GO:0047389) |
0.2 | 0.6 | GO:0005124 | scavenger receptor binding(GO:0005124) |
0.2 | 1.2 | GO:0070326 | very-low-density lipoprotein particle receptor binding(GO:0070326) |
0.2 | 1.0 | GO:0030618 | transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) |
0.2 | 4.2 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
0.2 | 0.8 | GO:0015410 | manganese-transporting ATPase activity(GO:0015410) |
0.2 | 1.7 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
0.2 | 0.8 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
0.2 | 2.5 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
0.2 | 0.5 | GO:0004487 | methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) |
0.2 | 2.3 | GO:0016755 | transferase activity, transferring amino-acyl groups(GO:0016755) |
0.2 | 8.2 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
0.2 | 1.9 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
0.2 | 1.0 | GO:0045322 | unmethylated CpG binding(GO:0045322) |
0.2 | 9.5 | GO:0036002 | pre-mRNA binding(GO:0036002) |
0.2 | 0.7 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
0.2 | 4.5 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
0.2 | 0.7 | GO:0004345 | glucose-6-phosphate dehydrogenase activity(GO:0004345) |
0.2 | 1.5 | GO:0050811 | GABA receptor binding(GO:0050811) |
0.2 | 3.5 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
0.2 | 3.5 | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
0.2 | 1.1 | GO:0004439 | phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) |
0.2 | 12.9 | GO:0019888 | protein phosphatase regulator activity(GO:0019888) |
0.2 | 1.1 | GO:0032051 | clathrin light chain binding(GO:0032051) |
0.2 | 5.7 | GO:0017022 | myosin binding(GO:0017022) |
0.2 | 1.0 | GO:0005042 | netrin receptor activity(GO:0005042) |
0.2 | 1.3 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
0.2 | 1.9 | GO:0022842 | leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842) |
0.2 | 0.6 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
0.2 | 0.9 | GO:0048039 | ubiquinone binding(GO:0048039) |
0.2 | 0.5 | GO:0004482 | mRNA (guanine-N7-)-methyltransferase activity(GO:0004482) |
0.1 | 4.8 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
0.1 | 0.7 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
0.1 | 3.0 | GO:0030506 | ankyrin binding(GO:0030506) |
0.1 | 3.4 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
0.1 | 0.7 | GO:0003956 | NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956) |
0.1 | 2.6 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
0.1 | 5.4 | GO:0046875 | ephrin receptor binding(GO:0046875) |
0.1 | 1.0 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
0.1 | 0.5 | GO:0004703 | G-protein coupled receptor kinase activity(GO:0004703) |
0.1 | 0.7 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
0.1 | 0.4 | GO:0071936 | coreceptor activity involved in Wnt signaling pathway(GO:0071936) |
0.1 | 2.2 | GO:0005521 | lamin binding(GO:0005521) |
0.1 | 0.8 | GO:0047391 | alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391) |
0.1 | 2.5 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
0.1 | 3.4 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
0.1 | 1.0 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
0.1 | 1.1 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
0.1 | 0.5 | GO:0005315 | inorganic phosphate transmembrane transporter activity(GO:0005315) |
0.1 | 0.4 | GO:0004534 | transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160) 5'-3' exoribonuclease activity(GO:0004534) |
0.1 | 1.9 | GO:0042043 | neurexin family protein binding(GO:0042043) |
0.1 | 1.3 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
0.1 | 0.6 | GO:0004305 | ethanolamine kinase activity(GO:0004305) |
0.1 | 0.8 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
0.1 | 1.3 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
0.1 | 3.2 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
0.1 | 0.3 | GO:0047256 | beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256) |
0.1 | 1.4 | GO:0005522 | profilin binding(GO:0005522) |
0.1 | 0.6 | GO:0004311 | farnesyltranstransferase activity(GO:0004311) |
0.1 | 10.7 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
0.1 | 1.2 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
0.1 | 0.4 | GO:0038025 | reelin receptor activity(GO:0038025) |
0.1 | 1.3 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
0.1 | 0.5 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
0.1 | 1.3 | GO:0005158 | insulin receptor binding(GO:0005158) |
0.1 | 0.3 | GO:0035851 | Krueppel-associated box domain binding(GO:0035851) |
0.1 | 0.6 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
0.1 | 1.3 | GO:0042288 | MHC class I protein binding(GO:0042288) |
0.1 | 26.6 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
0.1 | 1.0 | GO:1902936 | phosphatidylinositol bisphosphate binding(GO:1902936) |
0.1 | 1.2 | GO:0005314 | high-affinity glutamate transmembrane transporter activity(GO:0005314) |
0.1 | 0.8 | GO:0031996 | thioesterase binding(GO:0031996) |
0.1 | 1.0 | GO:0047555 | 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555) |
0.1 | 0.6 | GO:0016714 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714) |
0.1 | 20.4 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
0.1 | 0.5 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
0.1 | 0.3 | GO:0030249 | guanylate cyclase regulator activity(GO:0030249) |
0.1 | 1.9 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
0.1 | 0.2 | GO:0019107 | glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107) |
0.1 | 0.7 | GO:0016917 | GABA receptor activity(GO:0016917) |
0.1 | 1.5 | GO:0035497 | cAMP response element binding(GO:0035497) |
0.1 | 0.2 | GO:0033680 | ATP-dependent DNA/RNA helicase activity(GO:0033680) |
0.1 | 0.9 | GO:0004629 | phospholipase C activity(GO:0004629) |
0.1 | 1.2 | GO:0070300 | phosphatidic acid binding(GO:0070300) |
0.1 | 2.8 | GO:0004364 | glutathione transferase activity(GO:0004364) |
0.1 | 4.4 | GO:0051219 | phosphoprotein binding(GO:0051219) |
0.1 | 0.9 | GO:0003680 | AT DNA binding(GO:0003680) |
0.1 | 1.0 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
0.1 | 0.5 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
0.1 | 0.4 | GO:0048248 | CXCR3 chemokine receptor binding(GO:0048248) |
0.1 | 1.4 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
0.1 | 0.8 | GO:0004622 | lysophospholipase activity(GO:0004622) |
0.1 | 0.1 | GO:1904288 | BAT3 complex binding(GO:1904288) |
0.1 | 4.2 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.1 | 1.2 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
0.1 | 0.9 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
0.1 | 1.3 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
0.1 | 0.7 | GO:0048185 | activin binding(GO:0048185) |
0.1 | 1.9 | GO:0005112 | Notch binding(GO:0005112) |
0.1 | 0.7 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
0.1 | 0.3 | GO:0015186 | L-glutamine transmembrane transporter activity(GO:0015186) |
0.1 | 8.4 | GO:0017137 | Rab GTPase binding(GO:0017137) |
0.1 | 3.5 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
0.1 | 1.4 | GO:0051721 | protein phosphatase 2A binding(GO:0051721) |
0.1 | 0.5 | GO:0043560 | insulin receptor substrate binding(GO:0043560) |
0.1 | 0.7 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
0.1 | 11.7 | GO:0005096 | GTPase activator activity(GO:0005096) |
0.1 | 2.8 | GO:0015485 | cholesterol binding(GO:0015485) |
0.1 | 0.4 | GO:0070579 | methylcytosine dioxygenase activity(GO:0070579) |
0.1 | 1.3 | GO:0003924 | GTPase activity(GO:0003924) |
0.1 | 0.3 | GO:0098821 | BMP receptor activity(GO:0098821) |
0.1 | 1.9 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.1 | 0.7 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
0.1 | 1.4 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
0.0 | 2.0 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
0.0 | 1.5 | GO:0005516 | calmodulin binding(GO:0005516) |
0.0 | 1.0 | GO:0042169 | SH2 domain binding(GO:0042169) |
0.0 | 2.7 | GO:0030674 | protein binding, bridging(GO:0030674) |
0.0 | 0.6 | GO:0031683 | G-protein beta/gamma-subunit complex binding(GO:0031683) |
0.0 | 0.2 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
0.0 | 0.3 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
0.0 | 0.0 | GO:0070012 | oligopeptidase activity(GO:0070012) |
0.0 | 0.9 | GO:0008327 | methyl-CpG binding(GO:0008327) |
0.0 | 2.4 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
0.0 | 0.6 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
0.0 | 0.3 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
0.0 | 0.8 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
0.0 | 2.1 | GO:0050840 | extracellular matrix binding(GO:0050840) |
0.0 | 0.8 | GO:0000900 | translation repressor activity, nucleic acid binding(GO:0000900) |
0.0 | 0.3 | GO:0016215 | acyl-CoA desaturase activity(GO:0016215) |
0.0 | 0.3 | GO:0051021 | GDP-dissociation inhibitor binding(GO:0051021) |
0.0 | 0.5 | GO:0004385 | guanylate kinase activity(GO:0004385) |
0.0 | 0.3 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
0.0 | 0.7 | GO:0017160 | Ral GTPase binding(GO:0017160) |
0.0 | 3.5 | GO:0008565 | protein transporter activity(GO:0008565) |
0.0 | 0.7 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
0.0 | 2.7 | GO:0005057 | receptor signaling protein activity(GO:0005057) |
0.0 | 0.6 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
0.0 | 1.1 | GO:0004601 | peroxidase activity(GO:0004601) |
0.0 | 2.1 | GO:0051117 | ATPase binding(GO:0051117) |
0.0 | 0.8 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
0.0 | 0.2 | GO:0015037 | peptide disulfide oxidoreductase activity(GO:0015037) |
0.0 | 0.5 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
0.0 | 0.9 | GO:0008376 | acetylgalactosaminyltransferase activity(GO:0008376) |
0.0 | 0.2 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
0.0 | 0.4 | GO:0005496 | steroid binding(GO:0005496) |
0.0 | 1.5 | GO:0019003 | GDP binding(GO:0019003) |
0.0 | 0.2 | GO:0008172 | S-methyltransferase activity(GO:0008172) |
0.0 | 0.2 | GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162) |
0.0 | 0.9 | GO:0018024 | histone-lysine N-methyltransferase activity(GO:0018024) |
0.0 | 0.5 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
0.0 | 0.3 | GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
0.0 | 0.7 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
0.0 | 0.9 | GO:0051183 | vitamin transporter activity(GO:0051183) |
0.0 | 0.2 | GO:0016670 | oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670) |
0.0 | 2.2 | GO:0015399 | primary active transmembrane transporter activity(GO:0015399) P-P-bond-hydrolysis-driven transmembrane transporter activity(GO:0015405) ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492) |
0.0 | 0.5 | GO:0048365 | Rac GTPase binding(GO:0048365) |
0.0 | 8.8 | GO:0050839 | cell adhesion molecule binding(GO:0050839) |
0.0 | 0.2 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
0.0 | 1.6 | GO:0017124 | SH3 domain binding(GO:0017124) |
0.0 | 1.4 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
0.0 | 0.2 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
0.0 | 0.1 | GO:0004844 | mismatch base pair DNA N-glycosylase activity(GO:0000700) uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506) |
0.0 | 0.9 | GO:0044325 | ion channel binding(GO:0044325) |
0.0 | 0.1 | GO:0000298 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) |
0.0 | 0.0 | GO:0043546 | molybdenum ion binding(GO:0030151) molybdopterin cofactor binding(GO:0043546) |
0.0 | 2.4 | GO:0004386 | helicase activity(GO:0004386) |
0.0 | 1.0 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
0.0 | 0.1 | GO:0050998 | nitric-oxide synthase binding(GO:0050998) |
0.0 | 0.6 | GO:0016627 | oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627) |
0.0 | 0.2 | GO:0016209 | antioxidant activity(GO:0016209) |
0.0 | 0.2 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
0.0 | 0.1 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 15.7 | PID_P38_GAMMA_DELTA_PATHWAY | Signaling mediated by p38-gamma and p38-delta |
0.5 | 22.8 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
0.5 | 3.7 | PID_INTEGRIN4_PATHWAY | Alpha6 beta4 integrin-ligand interactions |
0.4 | 4.3 | PID_THROMBIN_PAR4_PATHWAY | PAR4-mediated thrombin signaling events |
0.3 | 9.5 | PID_IL3_PATHWAY | IL3-mediated signaling events |
0.3 | 11.1 | PID_REELIN_PATHWAY | Reelin signaling pathway |
0.3 | 17.4 | PID_LKB1_PATHWAY | LKB1 signaling events |
0.2 | 2.9 | PID_VEGF_VEGFR_PATHWAY | VEGF and VEGFR signaling network |
0.2 | 10.3 | PID_TCPTP_PATHWAY | Signaling events mediated by TCPTP |
0.2 | 9.5 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
0.2 | 9.3 | PID_KIT_PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
0.2 | 8.1 | PID_RAC1_REG_PATHWAY | Regulation of RAC1 activity |
0.2 | 1.7 | PID_AJDISS_2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
0.1 | 4.5 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
0.1 | 3.5 | ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY | PI3K Pathway |
0.1 | 2.2 | PID_EPHA_FWDPATHWAY | EPHA forward signaling |
0.1 | 3.6 | ST_JNK_MAPK_PATHWAY | JNK MAPK Pathway |
0.1 | 2.0 | PID_ERBB2_ERBB3_PATHWAY | ErbB2/ErbB3 signaling events |
0.1 | 7.2 | PID_HIF1_TFPATHWAY | HIF-1-alpha transcription factor network |
0.1 | 0.5 | PID_ERBB_NETWORK_PATHWAY | ErbB receptor signaling network |
0.1 | 4.6 | PID_FOXO_PATHWAY | FoxO family signaling |
0.1 | 3.0 | PID_INSULIN_PATHWAY | Insulin Pathway |
0.1 | 1.3 | PID_RET_PATHWAY | Signaling events regulated by Ret tyrosine kinase |
0.1 | 3.9 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
0.1 | 1.7 | PID_ER_NONGENOMIC_PATHWAY | Plasma membrane estrogen receptor signaling |
0.1 | 4.6 | PID_PDGFRB_PATHWAY | PDGFR-beta signaling pathway |
0.1 | 0.9 | PID_SYNDECAN_3_PATHWAY | Syndecan-3-mediated signaling events |
0.1 | 1.4 | PID_MAPK_TRK_PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
0.1 | 1.9 | SIG_CD40PATHWAYMAP | Genes related to CD40 signaling |
0.1 | 2.9 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
0.1 | 1.3 | PID_IFNG_PATHWAY | IFN-gamma pathway |
0.1 | 1.0 | PID_NFAT_TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
0.1 | 1.3 | PID_EPHB_FWD_PATHWAY | EPHB forward signaling |
0.1 | 0.4 | ST_JAK_STAT_PATHWAY | Jak-STAT Pathway |
0.1 | 0.4 | PID_CD40_PATHWAY | CD40/CD40L signaling |
0.1 | 1.3 | PID_ERBB1_INTERNALIZATION_PATHWAY | Internalization of ErbB1 |
0.0 | 1.1 | ST_G_ALPHA_I_PATHWAY | G alpha i Pathway |
0.0 | 1.6 | SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES | Genes related to regulation of the actin cytoskeleton |
0.0 | 1.3 | PID_TCR_PATHWAY | TCR signaling in naïve CD4+ T cells |
0.0 | 1.0 | PID_IL4_2PATHWAY | IL4-mediated signaling events |
0.0 | 4.9 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.0 | 0.5 | PID_NCADHERIN_PATHWAY | N-cadherin signaling events |
0.0 | 0.4 | PID_IL6_7_PATHWAY | IL6-mediated signaling events |
0.0 | 0.6 | PID_ALPHA_SYNUCLEIN_PATHWAY | Alpha-synuclein signaling |
0.0 | 0.8 | PID_ERBB1_DOWNSTREAM_PATHWAY | ErbB1 downstream signaling |
0.0 | 0.3 | PID_ERB_GENOMIC_PATHWAY | Validated nuclear estrogen receptor beta network |
0.0 | 0.5 | PID_GLYPICAN_1PATHWAY | Glypican 1 network |
0.0 | 0.4 | PID_ARF6_DOWNSTREAM_PATHWAY | Arf6 downstream pathway |
0.0 | 0.6 | PID_TRKR_PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
0.0 | 0.4 | ST_TUMOR_NECROSIS_FACTOR_PATHWAY | Tumor Necrosis Factor Pathway. |
0.0 | 0.6 | PID_INTEGRIN_A4B1_PATHWAY | Alpha4 beta1 integrin signaling events |
0.0 | 2.1 | PID_P53_DOWNSTREAM_PATHWAY | Direct p53 effectors |
0.0 | 0.4 | PID_WNT_CANONICAL_PATHWAY | Canonical Wnt signaling pathway |
0.0 | 0.2 | PID_SYNDECAN_2_PATHWAY | Syndecan-2-mediated signaling events |
0.0 | 0.4 | PID_ECADHERIN_STABILIZATION_PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
0.0 | 0.3 | PID_TXA2PATHWAY | Thromboxane A2 receptor signaling |
0.0 | 0.2 | PID_ALK1_PATHWAY | ALK1 signaling events |
0.0 | 0.4 | PID_TGFBR_PATHWAY | TGF-beta receptor signaling |
0.0 | 0.9 | PID_HDAC_CLASSI_PATHWAY | Signaling events mediated by HDAC Class I |
0.0 | 0.2 | PID_ARF6_PATHWAY | Arf6 signaling events |
0.0 | 0.1 | PID_PTP1B_PATHWAY | Signaling events mediated by PTP1B |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 13.2 | REACTOME_CRMPS_IN_SEMA3A_SIGNALING | Genes involved in CRMPs in Sema3A signaling |
0.6 | 6.8 | REACTOME_IL_7_SIGNALING | Genes involved in Interleukin-7 signaling |
0.5 | 12.8 | REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII | Genes involved in CREB phosphorylation through the activation of CaMKII |
0.5 | 11.5 | REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
0.4 | 7.8 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION | Genes involved in N-Glycan antennae elongation |
0.4 | 6.4 | REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
0.4 | 4.0 | REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
0.4 | 5.6 | REACTOME_INFLAMMASOMES | Genes involved in Inflammasomes |
0.4 | 2.1 | REACTOME_ERKS_ARE_INACTIVATED | Genes involved in ERKs are inactivated |
0.3 | 8.2 | REACTOME_OTHER_SEMAPHORIN_INTERACTIONS | Genes involved in Other semaphorin interactions |
0.3 | 5.4 | REACTOME_GABA_A_RECEPTOR_ACTIVATION | Genes involved in GABA A receptor activation |
0.3 | 6.3 | REACTOME_REGULATION_OF_KIT_SIGNALING | Genes involved in Regulation of KIT signaling |
0.3 | 38.6 | REACTOME_L1CAM_INTERACTIONS | Genes involved in L1CAM interactions |
0.3 | 7.7 | REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
0.3 | 10.0 | REACTOME_DARPP_32_EVENTS | Genes involved in DARPP-32 events |
0.3 | 0.5 | REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION | Genes involved in FGFR4 ligand binding and activation |
0.2 | 4.0 | REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH | Genes involved in NCAM signaling for neurite out-growth |
0.2 | 6.3 | REACTOME_CGMP_EFFECTS | Genes involved in cGMP effects |
0.2 | 1.6 | REACTOME_DSCAM_INTERACTIONS | Genes involved in DSCAM interactions |
0.2 | 8.6 | REACTOME_GLYCOLYSIS | Genes involved in Glycolysis |
0.2 | 1.3 | REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS | Genes involved in Elevation of cytosolic Ca2+ levels |
0.2 | 1.0 | REACTOME_OLFACTORY_SIGNALING_PATHWAY | Genes involved in Olfactory Signaling Pathway |
0.2 | 1.7 | REACTOME_ERK_MAPK_TARGETS | Genes involved in ERK/MAPK targets |
0.2 | 0.2 | REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN | Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein |
0.2 | 7.8 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
0.2 | 0.6 | REACTOME_SYNTHESIS_OF_PE | Genes involved in Synthesis of PE |
0.2 | 7.4 | REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
0.2 | 0.4 | REACTOME_PLATELET_SENSITIZATION_BY_LDL | Genes involved in Platelet sensitization by LDL |
0.2 | 2.3 | REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
0.2 | 3.5 | REACTOME_POTASSIUM_CHANNELS | Genes involved in Potassium Channels |
0.2 | 2.6 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
0.2 | 2.6 | REACTOME_TIE2_SIGNALING | Genes involved in Tie2 Signaling |
0.2 | 3.8 | REACTOME_SYNTHESIS_OF_PC | Genes involved in Synthesis of PC |
0.2 | 2.2 | REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
0.1 | 0.6 | REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT | Genes involved in Regulation of beta-cell development |
0.1 | 1.0 | REACTOME_REGULATION_OF_SIGNALING_BY_CBL | Genes involved in Regulation of signaling by CBL |
0.1 | 10.1 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | Genes involved in NRAGE signals death through JNK |
0.1 | 2.6 | REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
0.1 | 1.6 | REACTOME_ARMS_MEDIATED_ACTIVATION | Genes involved in ARMS-mediated activation |
0.1 | 2.7 | REACTOME_SIGNALING_BY_NODAL | Genes involved in Signaling by NODAL |
0.1 | 1.3 | REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
0.1 | 2.0 | REACTOME_NEPHRIN_INTERACTIONS | Genes involved in Nephrin interactions |
0.1 | 1.0 | REACTOME_IL_3_5_AND_GM_CSF_SIGNALING | Genes involved in Interleukin-3, 5 and GM-CSF signaling |
0.1 | 1.5 | REACTOME_IRAK1_RECRUITS_IKK_COMPLEX | Genes involved in IRAK1 recruits IKK complex |
0.1 | 2.4 | REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
0.1 | 1.0 | REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
0.1 | 1.4 | REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
0.1 | 0.8 | REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR | Genes involved in Thromboxane signalling through TP receptor |
0.1 | 0.7 | REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
0.1 | 0.5 | REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
0.1 | 1.6 | REACTOME_KERATAN_SULFATE_BIOSYNTHESIS | Genes involved in Keratan sulfate biosynthesis |
0.1 | 1.1 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
0.1 | 0.6 | REACTOME_SIGNALING_BY_ACTIVATED_POINT_MUTANTS_OF_FGFR1 | Genes involved in Signaling by activated point mutants of FGFR1 |
0.1 | 3.9 | REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
0.1 | 1.9 | REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING | Genes involved in Growth hormone receptor signaling |
0.1 | 0.9 | REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE | Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline |
0.1 | 2.3 | REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT | Genes involved in ABC-family proteins mediated transport |
0.1 | 1.1 | REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
0.1 | 0.6 | REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
0.1 | 1.2 | REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 | Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
0.1 | 1.5 | REACTOME_RAP1_SIGNALLING | Genes involved in Rap1 signalling |
0.1 | 8.3 | REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
0.1 | 1.0 | REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
0.1 | 0.8 | REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES | Genes involved in Generation of second messenger molecules |
0.1 | 0.7 | REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
0.1 | 6.4 | REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES | Genes involved in Transmission across Chemical Synapses |
0.1 | 0.3 | REACTOME_G_ALPHA1213_SIGNALLING_EVENTS | Genes involved in G alpha (12/13) signalling events |
0.1 | 0.4 | REACTOME_NOD1_2_SIGNALING_PATHWAY | Genes involved in NOD1/2 Signaling Pathway |
0.1 | 0.6 | REACTOME_AMINE_LIGAND_BINDING_RECEPTORS | Genes involved in Amine ligand-binding receptors |
0.1 | 1.8 | REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING | Genes involved in Sema4D in semaphorin signaling |
0.0 | 0.7 | REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS | Genes involved in Activation of BH3-only proteins |
0.0 | 1.0 | REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |
0.0 | 1.4 | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
0.0 | 0.4 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PG | Genes involved in Acyl chain remodelling of PG |
0.0 | 1.0 | REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
0.0 | 0.2 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI | Genes involved in N-glycan antennae elongation in the medial/trans-Golgi |
0.0 | 3.1 | REACTOME_SIGNALING_BY_RHO_GTPASES | Genes involved in Signaling by Rho GTPases |
0.0 | 1.6 | REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION | Genes involved in MHC class II antigen presentation |
0.0 | 0.6 | REACTOME_G0_AND_EARLY_G1 | Genes involved in G0 and Early G1 |
0.0 | 1.0 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | Genes involved in Ion transport by P-type ATPases |
0.0 | 2.0 | REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
0.0 | 0.4 | REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP | Genes involved in Destabilization of mRNA by Tristetraprolin (TTP) |
0.0 | 0.2 | REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS | Genes involved in Intrinsic Pathway for Apoptosis |
0.0 | 0.2 | REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
0.0 | 1.3 | REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ | Genes involved in Response to elevated platelet cytosolic Ca2+ |
0.0 | 1.8 | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_ | Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
0.0 | 0.5 | REACTOME_SIGNALING_BY_HIPPO | Genes involved in Signaling by Hippo |
0.0 | 0.3 | REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
0.0 | 0.2 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
0.0 | 2.9 | REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
0.0 | 0.8 | REACTOME_MEIOTIC_SYNAPSIS | Genes involved in Meiotic Synapsis |