Motif ID: Maf_Nrl

Z-value: 0.616

Transcription factors associated with Maf_Nrl:

Gene SymbolEntrez IDGene Name
Maf ENSMUSG00000055435.6 Maf
Nrl ENSMUSG00000040632.9 Nrl

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mafmm10_v2_chr8_-_115707778_115707794-0.408.7e-03Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Maf_Nrl

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_103853199 4.037 ENSMUST00000033229.3
Hbb-y
hemoglobin Y, beta-like embryonic chain
chr1_+_90203980 3.910 ENSMUST00000065587.4
ENSMUST00000159654.1
Ackr3

atypical chemokine receptor 3

chr7_-_75308373 2.338 ENSMUST00000085164.5
Sv2b
synaptic vesicle glycoprotein 2 b
chr14_-_49525840 2.280 ENSMUST00000138884.1
ENSMUST00000074368.4
ENSMUST00000123534.1
Slc35f4


solute carrier family 35, member F4


chr15_-_93519499 2.115 ENSMUST00000109255.2
Prickle1
prickle homolog 1 (Drosophila)
chr11_-_77725281 2.090 ENSMUST00000078623.4
Cryba1
crystallin, beta A1
chr7_+_121707189 1.742 ENSMUST00000065310.2
1700069B07Rik
RIKEN cDNA 1700069B07 gene
chr15_-_67113909 1.724 ENSMUST00000092640.5
St3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr2_-_118373347 1.661 ENSMUST00000039160.2
Gpr176
G protein-coupled receptor 176
chr2_-_156887172 1.485 ENSMUST00000109561.3
Sla2
Src-like-adaptor 2
chr3_-_79145875 1.430 ENSMUST00000118340.1
Rapgef2
Rap guanine nucleotide exchange factor (GEF) 2
chr2_-_156887056 1.426 ENSMUST00000029164.2
Sla2
Src-like-adaptor 2
chr15_+_89453913 1.346 ENSMUST00000023291.5
Mapk8ip2
mitogen-activated protein kinase 8 interacting protein 2
chr11_+_76202007 1.302 ENSMUST00000094014.3
Fam57a
family with sequence similarity 57, member A
chr16_+_78930940 1.255 ENSMUST00000114216.1
ENSMUST00000069148.6
ENSMUST00000023568.7
Chodl


chondrolectin


chr11_+_76202084 1.222 ENSMUST00000169560.1
Fam57a
family with sequence similarity 57, member A
chr2_-_151632471 1.193 ENSMUST00000137936.1
ENSMUST00000146172.1
ENSMUST00000094456.3
ENSMUST00000148755.1
ENSMUST00000109875.1
ENSMUST00000028951.7
ENSMUST00000109877.3
Snph






syntaphilin






chr11_-_79059872 1.092 ENSMUST00000141409.1
Ksr1
kinase suppressor of ras 1
chr12_-_111672290 1.040 ENSMUST00000001304.7
Ckb
creatine kinase, brain
chr6_-_138422898 1.011 ENSMUST00000161450.1
ENSMUST00000163024.1
ENSMUST00000162185.1
Lmo3


LIM domain only 3


chr18_-_43059418 0.977 ENSMUST00000025377.7
Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr18_-_61707583 0.954 ENSMUST00000025472.1
Pcyox1l
prenylcysteine oxidase 1 like
chr1_-_183147461 0.952 ENSMUST00000171366.1
Disp1
dispatched homolog 1 (Drosophila)
chr7_+_29309429 0.926 ENSMUST00000137848.1
Dpf1
D4, zinc and double PHD fingers family 1
chr7_+_82337218 0.923 ENSMUST00000173828.1
Adamtsl3
ADAMTS-like 3
chr1_+_62703285 0.892 ENSMUST00000102822.2
ENSMUST00000075144.5
Nrp2

neuropilin 2

chr9_+_87022014 0.876 ENSMUST00000168529.2
ENSMUST00000174724.1
ENSMUST00000173126.1
Cyb5r4


cytochrome b5 reductase 4


chr5_+_110544326 0.875 ENSMUST00000040001.7
Galnt9
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9
chr1_-_136260873 0.840 ENSMUST00000086395.5
Gpr25
G protein-coupled receptor 25
chr7_+_66839752 0.831 ENSMUST00000107478.1
Adamts17
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 17
chr7_+_66839726 0.826 ENSMUST00000098382.3
Adamts17
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 17
chr4_+_101507947 0.825 ENSMUST00000149047.1
ENSMUST00000106929.3
Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr4_+_101507855 0.796 ENSMUST00000038207.5
Dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr16_-_18621366 0.789 ENSMUST00000051160.2
Gp1bb
glycoprotein Ib, beta polypeptide
chr8_+_94666722 0.786 ENSMUST00000034228.8
Arl2bp
ADP-ribosylation factor-like 2 binding protein
chr3_-_120886691 0.773 ENSMUST00000182099.1
ENSMUST00000183168.1
ENSMUST00000183276.1
ENSMUST00000182124.1
6530403H02Rik



RIKEN cDNA 6530403H02 gene



chr12_-_15816762 0.757 ENSMUST00000020922.7
Trib2
tribbles homolog 2 (Drosophila)
chr9_-_73968901 0.747 ENSMUST00000184666.1
Unc13c
unc-13 homolog C (C. elegans)
chr12_+_108605757 0.740 ENSMUST00000109854.2
Evl
Ena-vasodilator stimulated phosphoprotein
chr10_+_56377300 0.732 ENSMUST00000068581.7
Gja1
gap junction protein, alpha 1
chr7_-_103843154 0.718 ENSMUST00000063957.4
Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr6_-_92481343 0.709 ENSMUST00000113445.1
Prickle2
prickle homolog 2 (Drosophila)
chr5_-_24730635 0.705 ENSMUST00000068693.5
Wdr86
WD repeat domain 86
chr3_-_95228636 0.703 ENSMUST00000065482.5
Mllt11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr14_-_70635946 0.702 ENSMUST00000022695.9
Dmtn
dematin actin binding protein
chr10_+_69213084 0.685 ENSMUST00000163497.1
ENSMUST00000164212.1
ENSMUST00000067908.7
Rhobtb1


Rho-related BTB domain containing 1


chr11_-_65788275 0.671 ENSMUST00000152096.1
ENSMUST00000046963.3
Map2k4

mitogen-activated protein kinase kinase 4

chr7_-_70360593 0.653 ENSMUST00000032768.7
Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr16_+_90386382 0.647 ENSMUST00000065856.6
Hunk
hormonally upregulated Neu-associated kinase
chr7_+_99267428 0.622 ENSMUST00000068973.4
ENSMUST00000122101.1
Map6

microtubule-associated protein 6

chr1_+_110099295 0.619 ENSMUST00000134301.1
Cdh7
cadherin 7, type 2
chr10_-_127060163 0.586 ENSMUST00000040307.5
March9
membrane-associated ring finger (C3HC4) 9
chr2_+_120476911 0.585 ENSMUST00000110716.1
ENSMUST00000028748.6
ENSMUST00000090028.5
ENSMUST00000110719.2
Capn3



calpain 3



chr1_-_118982551 0.578 ENSMUST00000159678.1
Gli2
GLI-Kruppel family member GLI2
chr14_-_73385225 0.578 ENSMUST00000022704.7
Itm2b
integral membrane protein 2B
chr3_+_95228732 0.574 ENSMUST00000053872.5
Cdc42se1
CDC42 small effector 1
chr19_-_21652779 0.572 ENSMUST00000179768.1
ENSMUST00000178523.1
ENSMUST00000038830.3
1110059E24Rik


RIKEN cDNA 1110059E24 gene


chr1_+_129273344 0.565 ENSMUST00000073527.6
ENSMUST00000040311.7
Thsd7b

thrombospondin, type I, domain containing 7B

chr10_+_4710119 0.565 ENSMUST00000105588.1
ENSMUST00000105589.1
Esr1

estrogen receptor 1 (alpha)

chr10_+_69212634 0.552 ENSMUST00000020101.5
Rhobtb1
Rho-related BTB domain containing 1
chr2_-_32312162 0.551 ENSMUST00000155269.1
Dnm1
dynamin 1
chr3_-_33083016 0.550 ENSMUST00000078226.3
ENSMUST00000108224.1
Pex5l

peroxisomal biogenesis factor 5-like

chr2_+_181767040 0.550 ENSMUST00000108756.1
Myt1
myelin transcription factor 1
chr13_+_113342548 0.540 ENSMUST00000078163.7
BC067074
cDNA sequence BC067074
chr9_-_99140065 0.539 ENSMUST00000035037.7
Pik3cb
phosphatidylinositol 3-kinase, catalytic, beta polypeptide
chr3_-_33082004 0.538 ENSMUST00000108225.3
Pex5l
peroxisomal biogenesis factor 5-like
chr19_+_38264761 0.533 ENSMUST00000087252.5
Lgi1
leucine-rich repeat LGI family, member 1
chr2_+_181767283 0.513 ENSMUST00000108757.2
Myt1
myelin transcription factor 1
chr9_+_96895617 0.507 ENSMUST00000071781.6
Gm10123
predicted pseudogene 10123
chr4_+_138454305 0.504 ENSMUST00000050918.3
Camk2n1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr14_-_102982630 0.494 ENSMUST00000184744.1
KCTD12
mmu-mir-5130
chr4_+_14864076 0.476 ENSMUST00000029875.3
Tmem55a
transmembrane protein 55A
chr6_+_55037988 0.465 ENSMUST00000003572.8
Gars
glycyl-tRNA synthetase
chr19_+_20601958 0.459 ENSMUST00000087638.3
Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
chr8_+_94667082 0.456 ENSMUST00000109527.4
Arl2bp
ADP-ribosylation factor-like 2 binding protein
chr2_+_153031852 0.455 ENSMUST00000037235.6
Xkr7
X Kell blood group precursor related family member 7 homolog
chr5_-_115652974 0.455 ENSMUST00000121746.1
ENSMUST00000118576.1
Ccdc64

coiled-coil domain containing 64

chr18_-_35655185 0.453 ENSMUST00000097619.1
Prob1
proline rich basic protein 1
chr10_+_128411616 0.445 ENSMUST00000096386.5
ENSMUST00000171342.1
Rnf41

ring finger protein 41

chr14_+_74640840 0.442 ENSMUST00000036653.3
Htr2a
5-hydroxytryptamine (serotonin) receptor 2A
chr11_+_69991633 0.441 ENSMUST00000108592.1
Gabarap
gamma-aminobutyric acid receptor associated protein
chr2_+_151543877 0.434 ENSMUST00000142271.1
Fkbp1a
FK506 binding protein 1a
chr11_+_76945719 0.418 ENSMUST00000125145.1
Blmh
bleomycin hydrolase
chr4_+_94739276 0.417 ENSMUST00000073939.6
ENSMUST00000102798.1
Tek

endothelial-specific receptor tyrosine kinase

chr11_+_69324069 0.413 ENSMUST00000060956.6
ENSMUST00000108662.1
Trappc1

trafficking protein particle complex 1

chr11_-_115699461 0.406 ENSMUST00000106497.1
Grb2
growth factor receptor bound protein 2
chr9_-_63399216 0.404 ENSMUST00000168665.1
2300009A05Rik
RIKEN cDNA 2300009A05 gene
chr11_-_35798884 0.402 ENSMUST00000160726.2
Fbll1
fibrillarin-like 1
chr17_-_89910449 0.402 ENSMUST00000086423.4
Gm10184
predicted pseudogene 10184
chr4_+_59003121 0.391 ENSMUST00000095070.3
ENSMUST00000174664.1
Dnajc25
Gm20503
DnaJ (Hsp40) homolog, subfamily C, member 25
predicted gene 20503
chr3_-_58525867 0.390 ENSMUST00000029385.7
Serp1
stress-associated endoplasmic reticulum protein 1
chr10_+_116143881 0.390 ENSMUST00000105271.2
Ptprr
protein tyrosine phosphatase, receptor type, R
chr4_+_155522462 0.390 ENSMUST00000177094.1
Gnb1
guanine nucleotide binding protein (G protein), beta 1
chr2_-_27142429 0.386 ENSMUST00000151224.2
Fam163b
family with sequence similarity 163, member B
chr19_+_42255704 0.383 ENSMUST00000087123.5
Golga7b
golgi autoantigen, golgin subfamily a, 7B
chr11_+_69324055 0.378 ENSMUST00000102601.3
Trappc1
trafficking protein particle complex 1
chr11_-_100135928 0.374 ENSMUST00000107411.2
Krt15
keratin 15
chr11_+_120232921 0.374 ENSMUST00000122148.1
ENSMUST00000044985.7
Bahcc1

BAH domain and coiled-coil containing 1

chrX_-_143933204 0.362 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chr10_+_79910856 0.361 ENSMUST00000181321.1
Gm26602
predicted gene, 26602
chr6_+_110645572 0.357 ENSMUST00000071076.6
ENSMUST00000172951.1
Grm7

glutamate receptor, metabotropic 7

chr9_+_103112072 0.356 ENSMUST00000035155.6
Rab6b
RAB6B, member RAS oncogene family
chr1_+_127306706 0.356 ENSMUST00000171405.1
Mgat5
mannoside acetylglucosaminyltransferase 5
chr10_+_87859255 0.355 ENSMUST00000105300.2
Igf1
insulin-like growth factor 1
chr7_+_28267809 0.355 ENSMUST00000059596.6
Eid2
EP300 interacting inhibitor of differentiation 2
chr6_-_56362356 0.343 ENSMUST00000044505.7
ENSMUST00000166102.1
ENSMUST00000164037.1
ENSMUST00000114327.2
Pde1c



phosphodiesterase 1C



chr13_+_42709482 0.343 ENSMUST00000066928.5
ENSMUST00000148891.1
Phactr1

phosphatase and actin regulator 1

chr4_+_43578921 0.339 ENSMUST00000030190.8
Rgp1
RGP1 retrograde golgi transport homolog (S. cerevisiae)
chr19_-_6118491 0.330 ENSMUST00000113533.1
Sac3d1
SAC3 domain containing 1
chr9_-_70141484 0.329 ENSMUST00000034749.8
Fam81a
family with sequence similarity 81, member A
chrX_+_7638674 0.329 ENSMUST00000128890.1
Syp
synaptophysin
chr13_+_83504032 0.324 ENSMUST00000163888.1
ENSMUST00000005722.7
Mef2c

myocyte enhancer factor 2C

chr6_-_99520949 0.324 ENSMUST00000176565.1
Foxp1
forkhead box P1
chr17_-_70851710 0.324 ENSMUST00000166395.2
Tgif1
TGFB-induced factor homeobox 1
chr8_-_124897685 0.323 ENSMUST00000098312.2
Exoc8
exocyst complex component 8
chr11_-_115699307 0.323 ENSMUST00000106499.1
Grb2
growth factor receptor bound protein 2
chr19_-_24861828 0.315 ENSMUST00000047666.4
Pgm5
phosphoglucomutase 5
chr3_+_45378396 0.313 ENSMUST00000166126.1
ENSMUST00000170695.1
ENSMUST00000171554.1
Pcdh10


protocadherin 10


chr17_+_29614786 0.311 ENSMUST00000024817.7
Rnf8
ring finger protein 8
chr14_-_57746044 0.307 ENSMUST00000173990.1
ENSMUST00000022531.7
Lats2

large tumor suppressor 2

chr16_+_8830093 0.306 ENSMUST00000023150.5
1810013L24Rik
RIKEN cDNA 1810013L24 gene
chr2_+_34772089 0.297 ENSMUST00000028222.6
ENSMUST00000100171.2
Hspa5

heat shock protein 5

chr1_+_74284930 0.296 ENSMUST00000113805.1
ENSMUST00000027370.6
ENSMUST00000087226.4
Pnkd


paroxysmal nonkinesiogenic dyskinesia


chr6_-_124464772 0.293 ENSMUST00000008297.4
Clstn3
calsyntenin 3
chr4_+_154011731 0.286 ENSMUST00000169622.1
ENSMUST00000030894.8
Lrrc47

leucine rich repeat containing 47

chr9_+_75051977 0.285 ENSMUST00000170310.1
ENSMUST00000166549.1
Arpp19

cAMP-regulated phosphoprotein 19

chr3_-_146839365 0.284 ENSMUST00000084614.3
Gm10288
predicted gene 10288
chr15_-_56694525 0.283 ENSMUST00000050544.7
Has2
hyaluronan synthase 2
chr1_+_180568913 0.280 ENSMUST00000027777.6
Parp1
poly (ADP-ribose) polymerase family, member 1
chr11_-_95699143 0.275 ENSMUST00000062249.2
Gm9796
predicted gene 9796
chr6_-_99435345 0.272 ENSMUST00000113322.2
ENSMUST00000176850.1
ENSMUST00000176632.1
Foxp1


forkhead box P1


chr8_-_64693027 0.272 ENSMUST00000048967.7
Cpe
carboxypeptidase E
chr11_+_69323963 0.272 ENSMUST00000102602.1
Trappc1
trafficking protein particle complex 1
chr2_+_181763315 0.272 ENSMUST00000081125.4
Myt1
myelin transcription factor 1
chr2_-_118479635 0.266 ENSMUST00000110862.1
ENSMUST00000009693.8
Srp14

signal recognition particle 14

chr2_-_140671462 0.264 ENSMUST00000110057.2
Flrt3
fibronectin leucine rich transmembrane protein 3
chr8_-_69974367 0.261 ENSMUST00000116463.2
Gatad2a
GATA zinc finger domain containing 2A
chr19_+_60755947 0.261 ENSMUST00000088237.4
Nanos1
nanos homolog 1 (Drosophila)
chrX_+_6047453 0.260 ENSMUST00000103007.3
Nudt11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr2_-_30830333 0.258 ENSMUST00000041726.3
Asb6
ankyrin repeat and SOCS box-containing 6
chr3_-_141931523 0.255 ENSMUST00000106232.1
Bmpr1b
bone morphogenetic protein receptor, type 1B
chr2_+_118900377 0.252 ENSMUST00000151162.1
Bahd1
bromo adjacent homology domain containing 1
chr6_-_99521153 0.251 ENSMUST00000177227.1
Foxp1
forkhead box P1
chr10_+_41887428 0.241 ENSMUST00000041438.6
Sesn1
sestrin 1
chr7_-_141902361 0.236 ENSMUST00000055819.6
ENSMUST00000130439.1
ENSMUST00000001950.5
Tollip


toll interacting protein


chr11_+_80428598 0.231 ENSMUST00000173938.1
ENSMUST00000017572.7
Psmd11

proteasome (prosome, macropain) 26S subunit, non-ATPase, 11

chr7_-_45052865 0.227 ENSMUST00000057293.6
Prr12
proline rich 12
chrX_-_8074720 0.223 ENSMUST00000115636.3
ENSMUST00000115638.3
Suv39h1

suppressor of variegation 3-9 homolog 1 (Drosophila)

chr17_-_26508463 0.221 ENSMUST00000025025.6
Dusp1
dual specificity phosphatase 1
chr12_+_80644212 0.219 ENSMUST00000085245.5
Slc39a9
solute carrier family 39 (zinc transporter), member 9
chr7_+_97400003 0.217 ENSMUST00000032882.8
Ndufc2
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2
chrX_-_163761323 0.213 ENSMUST00000059320.2
Rnf138rt1
ring finger protein 138, retrogene 1
chr3_-_144205165 0.212 ENSMUST00000120539.1
Lmo4
LIM domain only 4
chr17_+_29614800 0.208 ENSMUST00000162588.1
Rnf8
ring finger protein 8
chr6_+_117168535 0.205 ENSMUST00000112866.1
ENSMUST00000112871.1
ENSMUST00000073043.4
Cxcl12


chemokine (C-X-C motif) ligand 12


chr2_-_30093642 0.204 ENSMUST00000102865.4
Zdhhc12
zinc finger, DHHC domain containing 12
chr11_+_32226481 0.203 ENSMUST00000020528.7
Mpg
N-methylpurine-DNA glycosylase
chr2_-_30093607 0.202 ENSMUST00000081838.6
Zdhhc12
zinc finger, DHHC domain containing 12
chr9_+_44398176 0.199 ENSMUST00000165839.1
Slc37a4
solute carrier family 37 (glucose-6-phosphate transporter), member 4
chr11_-_75422524 0.191 ENSMUST00000125982.1
ENSMUST00000137103.1
Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr14_+_120478443 0.188 ENSMUST00000062117.6
Rap2a
RAS related protein 2a
chr7_+_127769809 0.185 ENSMUST00000118865.1
ENSMUST00000061587.6
ENSMUST00000121504.1
Orai3


ORAI calcium release-activated calcium modulator 3


chr5_+_34573744 0.185 ENSMUST00000147574.1
ENSMUST00000146295.1
Add1

adducin 1 (alpha)

chr11_-_28584260 0.184 ENSMUST00000093253.3
ENSMUST00000109502.2
ENSMUST00000042534.8
Ccdc85a


coiled-coil domain containing 85A


chr13_+_72632597 0.184 ENSMUST00000172353.1
Irx2
Iroquois related homeobox 2 (Drosophila)
chr14_+_32321987 0.179 ENSMUST00000022480.7
Ogdhl
oxoglutarate dehydrogenase-like
chr5_-_30960326 0.172 ENSMUST00000074840.5
Preb
prolactin regulatory element binding
chr16_-_89508313 0.171 ENSMUST00000056118.2
Krtap7-1
keratin associated protein 7-1
chr11_-_86683761 0.170 ENSMUST00000018315.3
Vmp1
vacuole membrane protein 1
chr17_+_24896488 0.170 ENSMUST00000024978.6
Nme3
NME/NM23 nucleoside diphosphate kinase 3
chr3_+_96832142 0.166 ENSMUST00000107070.1
ENSMUST00000107069.1
Pdzk1

PDZ domain containing 1

chr12_-_4907229 0.166 ENSMUST00000142867.1
Ubxn2a
UBX domain protein 2A
chr6_-_8778106 0.165 ENSMUST00000151758.1
ENSMUST00000115519.1
ENSMUST00000153390.1
Ica1


islet cell autoantigen 1


chr17_-_48409729 0.155 ENSMUST00000160319.1
ENSMUST00000159535.1
ENSMUST00000078800.6
ENSMUST00000046719.7
ENSMUST00000162460.1
Nfya




nuclear transcription factor-Y alpha




chr12_+_38781093 0.152 ENSMUST00000161513.1
Etv1
ets variant gene 1
chr2_+_85136355 0.149 ENSMUST00000057019.7
Aplnr
apelin receptor
chr17_+_37050631 0.148 ENSMUST00000172792.1
ENSMUST00000174347.1
Gabbr1

gamma-aminobutyric acid (GABA) B receptor, 1

chr19_-_20727533 0.145 ENSMUST00000025656.3
Aldh1a7
aldehyde dehydrogenase family 1, subfamily A7
chr14_+_56887795 0.144 ENSMUST00000022511.8
Zmym2
zinc finger, MYM-type 2
chr12_-_85824506 0.144 ENSMUST00000021676.5
ENSMUST00000142331.1
0610007P14Rik

RIKEN cDNA 0610007P14 gene

chr4_-_43578824 0.142 ENSMUST00000030189.7
Gba2
glucosidase beta 2
chr17_-_34122311 0.141 ENSMUST00000025193.6
Brd2
bromodomain containing 2
chr7_+_51878967 0.139 ENSMUST00000051912.6
Gas2
growth arrest specific 2
chr10_+_43221466 0.139 ENSMUST00000095725.4
Pdss2
prenyl (solanesyl) diphosphate synthase, subunit 2
chr9_+_110052016 0.133 ENSMUST00000164930.1
ENSMUST00000163979.1
Map4

microtubule-associated protein 4

chr16_+_94570010 0.132 ENSMUST00000119878.1
Dyrk1a
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a
chr10_-_116473418 0.131 ENSMUST00000087965.4
ENSMUST00000164271.1
Kcnmb4

potassium large conductance calcium-activated channel, subfamily M, beta member 4

chr16_-_46155077 0.123 ENSMUST00000059524.5
Gm4737
predicted gene 4737
chr11_+_54304180 0.122 ENSMUST00000108904.3
ENSMUST00000108905.3
Acsl6

acyl-CoA synthetase long-chain family member 6

chr7_+_51879041 0.122 ENSMUST00000107591.2
Gas2
growth arrest specific 2
chr11_+_82035569 0.121 ENSMUST00000000193.5
Ccl2
chemokine (C-C motif) ligand 2
chr5_-_30960236 0.118 ENSMUST00000088063.2
Preb
prolactin regulatory element binding
chr16_+_20672716 0.118 ENSMUST00000044783.7
ENSMUST00000115463.1
ENSMUST00000142344.1
ENSMUST00000073840.5
ENSMUST00000140576.1
ENSMUST00000115457.1
Eif4g1





eukaryotic translation initiation factor 4, gamma 1





chr7_-_110862944 0.116 ENSMUST00000033050.3
Lyve1
lymphatic vessel endothelial hyaluronan receptor 1
chr10_+_87859062 0.116 ENSMUST00000095360.4
Igf1
insulin-like growth factor 1
chr7_-_105633479 0.113 ENSMUST00000147044.1
ENSMUST00000106791.1
Trim3

tripartite motif-containing 3

chr12_-_113361232 0.109 ENSMUST00000103423.1
Ighg3
Immunoglobulin heavy constant gamma 3
chr7_+_19228334 0.107 ENSMUST00000063976.8
Opa3
optic atrophy 3
chrX_+_150594420 0.106 ENSMUST00000112713.2
Pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr9_+_49102720 0.102 ENSMUST00000070390.5
ENSMUST00000167095.1
Tmprss5

transmembrane protease, serine 5 (spinesin)


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.8 GO:0015671 oxygen transport(GO:0015671)
0.7 2.1 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.5 1.4 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.3 2.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.3 1.0 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.3 0.9 GO:0021649 vestibulocochlear nerve structural organization(GO:0021649) ganglion morphogenesis(GO:0061552) dorsal root ganglion morphogenesis(GO:1904835)
0.3 1.6 GO:0072318 clathrin coat disassembly(GO:0072318)
0.2 0.7 GO:0003104 positive regulation of glomerular filtration(GO:0003104) cell communication by chemical coupling(GO:0010643)
0.2 0.7 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.2 0.5 GO:1900141 regulation of oligodendrocyte apoptotic process(GO:1900141) negative regulation of oligodendrocyte apoptotic process(GO:1900142)
0.2 0.7 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.2 2.9 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.2 2.3 GO:0060539 diaphragm development(GO:0060539)
0.2 0.6 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.2 1.0 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.2 0.3 GO:2000111 positive regulation of macrophage apoptotic process(GO:2000111)
0.2 1.1 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1 0.4 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.1 0.6 GO:0060032 notochord regression(GO:0060032)
0.1 0.6 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.1 0.7 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.1 0.7 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 1.3 GO:0046958 nonassociative learning(GO:0046958)
0.1 0.4 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.1 0.5 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.7 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 4.1 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 0.3 GO:0038003 opioid receptor signaling pathway(GO:0038003) regulation of opioid receptor signaling pathway(GO:2000474)
0.1 0.4 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.1 0.5 GO:0070535 histone H2A K63-linked ubiquitination(GO:0070535)
0.1 0.3 GO:0001827 inner cell mass cell fate commitment(GO:0001827)
0.1 0.3 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.1 1.0 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.1 0.4 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 0.3 GO:0048209 regulation of vesicle targeting, to, from or within Golgi(GO:0048209)
0.1 0.6 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1 0.3 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.5 GO:0015960 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.1 0.3 GO:0030070 insulin processing(GO:0030070)
0.1 0.5 GO:0033034 positive regulation of neutrophil apoptotic process(GO:0033031) positive regulation of myeloid cell apoptotic process(GO:0033034)
0.1 0.3 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.1 0.8 GO:0061470 interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619)
0.1 1.0 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1 0.4 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.1 0.6 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.1 0.4 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.1 0.4 GO:0007603 phototransduction, visible light(GO:0007603)
0.1 0.8 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.1 0.2 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 0.4 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 0.6 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.3 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.1 0.3 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 1.8 GO:0030818 negative regulation of cAMP biosynthetic process(GO:0030818)
0.1 0.3 GO:0001927 exocyst assembly(GO:0001927)
0.1 1.2 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.1 GO:0002030 inhibitory G-protein coupled receptor phosphorylation(GO:0002030)
0.0 0.7 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.2 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.0 0.1 GO:0060853 arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) blood vessel endothelial cell fate specification(GO:0097101)
0.0 0.3 GO:1901911 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.6 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.1 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.4 GO:0031000 response to caffeine(GO:0031000)
0.0 1.7 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.4 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.4 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.2 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.3 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.3 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.0 0.1 GO:0051795 positive regulation of catagen(GO:0051795)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.3 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.0 0.4 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.1 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.0 0.4 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.2 GO:0015879 carnitine transport(GO:0015879)
0.0 0.9 GO:0046677 response to antibiotic(GO:0046677)
0.0 1.1 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.2 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.0 0.2 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:0042573 retinoic acid metabolic process(GO:0042573)
0.0 0.5 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.3 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 1.2 GO:0045806 negative regulation of endocytosis(GO:0045806)
0.0 0.1 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 0.1 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.0 0.2 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0 0.2 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 0.2 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.5 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 0.2 GO:0042659 regulation of cell fate specification(GO:0042659)
0.0 0.2 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.1 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.6 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.4 GO:0006829 zinc II ion transport(GO:0006829)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.8 GO:0005833 hemoglobin complex(GO:0005833)
0.3 1.1 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.2 0.7 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.2 0.7 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 0.7 GO:0044305 calyx of Held(GO:0044305)
0.1 0.5 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 0.6 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 0.8 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 0.5 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 1.1 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.6 GO:0097542 ciliary tip(GO:0097542)
0.0 1.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 4.0 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.1 GO:0044299 C-fiber(GO:0044299)
0.0 0.9 GO:0071565 nBAF complex(GO:0071565)
0.0 0.4 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0 0.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.6 GO:0043196 varicosity(GO:0043196)
0.0 0.3 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.4 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.4 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.1 GO:0044753 amphisome(GO:0044753)
0.0 0.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.7 GO:0005771 multivesicular body(GO:0005771)
0.0 0.6 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 2.7 GO:0043195 terminal bouton(GO:0043195)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 4.3 GO:0005770 late endosome(GO:0005770)
0.0 0.7 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.3 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.4 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.6 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 0.2 GO:0043203 axon hillock(GO:0043203)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.5 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.2 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.4 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.8 GO:0045202 synapse(GO:0045202)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0016494 C-X-C chemokine receptor activity(GO:0016494) C-X-C chemokine binding(GO:0019958)
1.2 4.8 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.4 1.7 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.3 1.0 GO:0004111 creatine kinase activity(GO:0004111)
0.2 0.7 GO:0001565 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
0.2 2.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 1.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.2 0.6 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.2 0.7 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075) gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.2 1.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.2 0.5 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1 0.4 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.1 0.4 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.1 0.7 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 0.9 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 1.0 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.1 0.4 GO:0070905 serine binding(GO:0070905)
0.1 0.5 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 0.9 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 3.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 0.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.5 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.6 GO:0031432 titin binding(GO:0031432)
0.1 0.4 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 1.0 GO:0015197 peptide transporter activity(GO:0015197)
0.1 0.5 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 1.0 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 1.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.3 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 0.2 GO:0005124 scavenger receptor binding(GO:0005124)
0.1 0.6 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.1 0.3 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 0.7 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.3 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.3 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.3 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.4 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.4 GO:0048185 activin binding(GO:0048185)
0.0 0.5 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 1.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0050347 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.0 0.3 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.5 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 1.8 GO:0030295 protein kinase activator activity(GO:0030295)
0.0 0.1 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.0 0.4 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 1.8 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.3 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.3 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.2 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.0 0.3 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.2 GO:0019104 DNA N-glycosylase activity(GO:0019104)
0.0 2.2 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.3 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.3 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 1.7 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.8 GO:0043621 protein self-association(GO:0043621)
0.0 0.3 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.8 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 2.1 GO:0004930 G-protein coupled receptor activity(GO:0004930)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.1 2.2 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 3.6 PID_TCR_PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.4 PID_ALK2_PATHWAY ALK2 signaling events
0.0 0.9 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.0 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.6 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.9 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.0 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.0 0.4 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 1.0 PID_ATR_PATHWAY ATR signaling pathway
0.0 0.9 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.0 0.5 PID_ATM_PATHWAY ATM pathway
0.0 2.2 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID_SHP2_PATHWAY SHP2 signaling
0.0 0.3 PID_IL1_PATHWAY IL1-mediated signaling events
0.0 0.2 SIG_CD40PATHWAYMAP Genes related to CD40 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 0.4 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
0.1 0.5 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.1 0.8 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.1 0.4 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 0.9 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 1.3 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.1 1.5 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.1 1.6 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 0.5 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.5 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.7 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.7 REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.9 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.4 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.6 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.4 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.5 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.8 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.4 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.4 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.2 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.6 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.1 REACTOME_NRIF_SIGNALS_CELL_DEATH_FROM_THE_NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.7 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.2 REACTOME_IL1_SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.3 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 0.6 REACTOME_AMYLOIDS Genes involved in Amyloids
0.0 0.3 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets