Motif ID: Foxp2_Foxp3

Z-value: 0.745

Transcription factors associated with Foxp2_Foxp3:

Gene SymbolEntrez IDGene Name
Foxp2 ENSMUSG00000029563.10 Foxp2
Foxp3 ENSMUSG00000039521.6 Foxp3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxp2mm10_v2_chr6_+_15196949_151971020.462.3e-03Click!
Foxp3mm10_v2_chrX_+_7579666_7579693-0.251.1e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Foxp2_Foxp3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_+_66386292 10.314 ENSMUST00000039540.5
ENSMUST00000110253.2
March1

membrane-associated ring finger (C3HC4) 1

chr4_+_144892813 7.207 ENSMUST00000105744.1
ENSMUST00000171001.1
Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr4_+_144893077 6.057 ENSMUST00000154208.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr11_+_3332426 5.819 ENSMUST00000136474.1
Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr4_+_144893127 5.237 ENSMUST00000142808.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr4_-_87806296 4.670 ENSMUST00000126353.1
ENSMUST00000149357.1
Mllt3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr1_+_66386968 4.608 ENSMUST00000145419.1
Map2
microtubule-associated protein 2
chr3_+_5218516 4.498 ENSMUST00000175866.1
Zfhx4
zinc finger homeodomain 4
chr6_+_141524379 3.868 ENSMUST00000032362.9
Slco1c1
solute carrier organic anion transporter family, member 1c1
chr2_+_28641227 3.862 ENSMUST00000028155.5
ENSMUST00000113869.1
ENSMUST00000113867.2
Tsc1


tuberous sclerosis 1


chr15_-_58214882 3.846 ENSMUST00000022986.6
Fbxo32
F-box protein 32
chr19_+_4855129 3.743 ENSMUST00000119694.1
Ctsf
cathepsin F
chr10_+_60106452 3.652 ENSMUST00000165024.2
Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr8_+_34807287 3.651 ENSMUST00000033930.4
Dusp4
dual specificity phosphatase 4
chr3_+_5218589 3.570 ENSMUST00000177488.1
Zfhx4
zinc finger homeodomain 4
chr1_+_34005872 3.466 ENSMUST00000182296.1
Dst
dystonin
chr18_+_5593566 3.444 ENSMUST00000160910.1
Zeb1
zinc finger E-box binding homeobox 1
chr11_-_86993682 3.354 ENSMUST00000018571.4
Ypel2
yippee-like 2 (Drosophila)
chr5_+_3928033 3.230 ENSMUST00000143365.1
Akap9
A kinase (PRKA) anchor protein (yotiao) 9
chr11_+_69095217 3.100 ENSMUST00000101004.2
Per1
period circadian clock 1
chr3_+_5218546 3.090 ENSMUST00000026284.6
Zfhx4
zinc finger homeodomain 4
chr1_-_64956807 2.999 ENSMUST00000097713.1
Plekhm3
pleckstrin homology domain containing, family M, member 3
chr2_-_65529275 2.994 ENSMUST00000126837.1
Scn3a
sodium channel, voltage-gated, type III, alpha
chr10_+_29211637 2.971 ENSMUST00000092627.4
9330159F19Rik
RIKEN cDNA 9330159F19 gene
chr1_-_64956731 2.922 ENSMUST00000123225.1
Plekhm3
pleckstrin homology domain containing, family M, member 3
chr1_+_179546303 2.858 ENSMUST00000040706.8
Cnst
consortin, connexin sorting protein
chr2_+_136713444 2.813 ENSMUST00000028727.4
ENSMUST00000110098.3
Snap25

synaptosomal-associated protein 25

chr2_+_112265809 2.813 ENSMUST00000110991.2
Slc12a6
solute carrier family 12, member 6
chr13_-_93499803 2.780 ENSMUST00000065537.7
Jmy
junction-mediating and regulatory protein
chr7_+_82175156 2.672 ENSMUST00000180243.1
Sh3gl3
SH3-domain GRB2-like 3
chr4_-_53159885 2.515 ENSMUST00000030010.3
Abca1
ATP-binding cassette, sub-family A (ABC1), member 1
chrX_+_35888808 2.498 ENSMUST00000033419.6
Dock11
dedicator of cytokinesis 11
chr18_+_69344503 2.470 ENSMUST00000114985.3
Tcf4
transcription factor 4
chr14_-_88471396 2.447 ENSMUST00000061628.5
Pcdh20
protocadherin 20
chr12_-_100725028 2.434 ENSMUST00000043599.6
Rps6ka5
ribosomal protein S6 kinase, polypeptide 5
chr19_-_28010995 2.408 ENSMUST00000172907.1
ENSMUST00000046898.9
Rfx3

regulatory factor X, 3 (influences HLA class II expression)

chr6_-_39725193 2.394 ENSMUST00000101497.3
Braf
Braf transforming gene
chr1_-_170110491 2.267 ENSMUST00000027985.2
Ddr2
discoidin domain receptor family, member 2
chr2_-_60125651 2.226 ENSMUST00000112550.1
Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr3_-_146770218 2.207 ENSMUST00000106137.1
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr2_-_7395879 2.104 ENSMUST00000182404.1
Celf2
CUGBP, Elav-like family member 2
chr3_-_52104891 2.096 ENSMUST00000121440.1
Maml3
mastermind like 3 (Drosophila)
chr7_+_141476374 2.076 ENSMUST00000117634.1
Tspan4
tetraspanin 4
chr4_-_151108244 2.071 ENSMUST00000131948.1
Camta1
calmodulin binding transcription activator 1
chr9_-_40455670 2.067 ENSMUST00000165104.1
ENSMUST00000045682.5
Gramd1b

GRAM domain containing 1B

chr2_-_73892530 2.066 ENSMUST00000136958.1
ENSMUST00000112010.2
ENSMUST00000128531.1
ENSMUST00000112017.1
Atf2



activating transcription factor 2



chr5_+_107437908 2.061 ENSMUST00000094541.2
Btbd8
BTB (POZ) domain containing 8
chr18_+_37496997 2.044 ENSMUST00000059571.5
Pcdhb19
protocadherin beta 19
chr10_+_69925954 2.002 ENSMUST00000181974.1
ENSMUST00000182795.1
ENSMUST00000182437.1
Ank3


ankyrin 3, epithelial


chr1_-_128592284 1.990 ENSMUST00000052172.6
ENSMUST00000142893.1
Cxcr4

chemokine (C-X-C motif) receptor 4

chr15_+_25940846 1.989 ENSMUST00000110438.1
Fam134b
family with sequence similarity 134, member B
chr18_+_37489465 1.987 ENSMUST00000055949.2
Pcdhb18
protocadherin beta 18
chr19_-_28011138 1.980 ENSMUST00000174850.1
Rfx3
regulatory factor X, 3 (influences HLA class II expression)
chr12_+_52699297 1.947 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chr19_-_28963863 1.933 ENSMUST00000161813.1
4430402I18Rik
RIKEN cDNA 4430402I18 gene
chr1_-_64121389 1.928 ENSMUST00000055001.3
Klf7
Kruppel-like factor 7 (ubiquitous)
chr3_+_51693771 1.913 ENSMUST00000099104.2
Gm10729
predicted gene 10729
chr18_-_43393346 1.909 ENSMUST00000025379.7
Dpysl3
dihydropyrimidinase-like 3
chr12_+_35047180 1.891 ENSMUST00000048519.9
ENSMUST00000163677.1
Snx13

sorting nexin 13

chr16_+_43510267 1.882 ENSMUST00000114695.2
Zbtb20
zinc finger and BTB domain containing 20
chr16_+_20097554 1.848 ENSMUST00000023509.3
Klhl24
kelch-like 24
chr15_+_4375462 1.840 ENSMUST00000061925.4
Plcxd3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr16_-_34263179 1.826 ENSMUST00000114949.1
ENSMUST00000114954.1
Kalrn

kalirin, RhoGEF kinase

chr9_-_45955170 1.821 ENSMUST00000162072.1
Sidt2
SID1 transmembrane family, member 2
chr11_-_101226414 1.806 ENSMUST00000100417.2
ENSMUST00000107285.1
ENSMUST00000107284.1
Ezh1


enhancer of zeste homolog 1 (Drosophila)


chr8_+_23669653 1.804 ENSMUST00000042352.4
Zmat4
zinc finger, matrin type 4
chr11_+_54438188 1.790 ENSMUST00000046835.7
Fnip1
folliculin interacting protein 1
chr19_-_37207293 1.787 ENSMUST00000132580.1
ENSMUST00000079754.4
ENSMUST00000136286.1
ENSMUST00000126188.1
ENSMUST00000126781.1
Cpeb3




cytoplasmic polyadenylation element binding protein 3




chr17_+_70522083 1.767 ENSMUST00000148486.1
ENSMUST00000133717.1
Dlgap1

discs, large (Drosophila) homolog-associated protein 1

chr4_-_87806276 1.758 ENSMUST00000148059.1
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chrX_+_163911401 1.742 ENSMUST00000140845.1
Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr11_-_100397740 1.700 ENSMUST00000001592.8
ENSMUST00000107403.1
Jup

junction plakoglobin

chr13_+_80886095 1.698 ENSMUST00000161441.1
Arrdc3
arrestin domain containing 3
chr18_-_34624562 1.681 ENSMUST00000003876.3
ENSMUST00000115766.1
ENSMUST00000097626.3
ENSMUST00000115765.1
Brd8



bromodomain containing 8



chr3_-_146781351 1.663 ENSMUST00000005164.7
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr15_+_3270767 1.661 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
Sepp1



selenoprotein P, plasma, 1



chr5_+_3928267 1.658 ENSMUST00000044492.8
Akap9
A kinase (PRKA) anchor protein (yotiao) 9
chr13_+_55209776 1.643 ENSMUST00000099490.2
Nsd1
nuclear receptor-binding SET-domain protein 1
chr6_+_134830145 1.623 ENSMUST00000046303.5
Crebl2
cAMP responsive element binding protein-like 2
chr16_+_43235856 1.609 ENSMUST00000146708.1
Zbtb20
zinc finger and BTB domain containing 20
chr10_+_84576626 1.596 ENSMUST00000020223.7
Tcp11l2
t-complex 11 (mouse) like 2
chr2_-_73892588 1.591 ENSMUST00000154456.1
ENSMUST00000090802.4
ENSMUST00000055833.5
Atf2


activating transcription factor 2


chr10_+_69534208 1.582 ENSMUST00000182439.1
ENSMUST00000092434.5
ENSMUST00000092432.5
ENSMUST00000092431.5
ENSMUST00000054167.8
ENSMUST00000047061.6
Ank3





ankyrin 3, epithelial





chr5_-_99252839 1.581 ENSMUST00000168092.1
ENSMUST00000031276.8
Rasgef1b

RasGEF domain family, member 1B

chr2_+_3770673 1.576 ENSMUST00000177037.1
Fam107b
family with sequence similarity 107, member B
chr17_+_35076902 1.554 ENSMUST00000172494.1
ENSMUST00000172678.1
ENSMUST00000013910.4
Ly6g6e


lymphocyte antigen 6 complex, locus G6E


chr19_+_26750939 1.553 ENSMUST00000175953.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr2_-_181578906 1.551 ENSMUST00000136875.1
Uckl1
uridine-cytidine kinase 1-like 1
chr17_+_70561739 1.540 ENSMUST00000097288.2
Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr3_+_52268337 1.539 ENSMUST00000053764.5
Foxo1
forkhead box O1
chr14_+_55560480 1.513 ENSMUST00000121622.1
ENSMUST00000143431.1
ENSMUST00000150481.1
Dcaf11


DDB1 and CUL4 associated factor 11


chr6_+_30541582 1.499 ENSMUST00000096066.4
Cpa2
carboxypeptidase A2, pancreatic
chr7_-_12422488 1.498 ENSMUST00000120220.1
Zfp551
zinc fingr protein 551
chr2_-_20943413 1.496 ENSMUST00000140230.1
Arhgap21
Rho GTPase activating protein 21
chr14_+_61607455 1.495 ENSMUST00000051184.8
Kcnrg
potassium channel regulator
chr12_+_71136848 1.487 ENSMUST00000149564.1
ENSMUST00000045907.8
2700049A03Rik

RIKEN cDNA 2700049A03 gene

chr1_-_190170178 1.485 ENSMUST00000177288.1
Prox1
prospero-related homeobox 1
chr9_+_53850243 1.474 ENSMUST00000048485.5
Sln
sarcolipin
chr1_+_51289106 1.474 ENSMUST00000051572.6
Sdpr
serum deprivation response
chr9_+_78113275 1.472 ENSMUST00000009972.5
ENSMUST00000117330.1
ENSMUST00000044551.7
Ick


intestinal cell kinase


chr10_-_18234930 1.469 ENSMUST00000052648.8
ENSMUST00000080860.6
ENSMUST00000173243.1
Ccdc28a


coiled-coil domain containing 28A


chr1_-_54926311 1.460 ENSMUST00000179030.1
ENSMUST00000044359.9
Ankrd44

ankyrin repeat domain 44

chr8_+_19682268 1.459 ENSMUST00000153710.1
ENSMUST00000127799.1
Gm6483

predicted gene 6483

chr2_-_104712122 1.450 ENSMUST00000111118.1
ENSMUST00000028597.3
Tcp11l1

t-complex 11 like 1

chr19_+_23141183 1.450 ENSMUST00000036884.1
Klf9
Kruppel-like factor 9
chr5_-_96164147 1.438 ENSMUST00000137207.1
Cnot6l
CCR4-NOT transcription complex, subunit 6-like
chr2_-_73892619 1.437 ENSMUST00000112007.1
ENSMUST00000112016.2
Atf2

activating transcription factor 2

chr18_-_43373248 1.436 ENSMUST00000118043.1
Dpysl3
dihydropyrimidinase-like 3
chr4_-_118409219 1.428 ENSMUST00000075406.5
Szt2
seizure threshold 2
chr8_-_84773381 1.403 ENSMUST00000109764.1
Nfix
nuclear factor I/X
chr12_-_99393010 1.400 ENSMUST00000177451.1
Foxn3
forkhead box N3
chr12_-_31950210 1.398 ENSMUST00000176084.1
ENSMUST00000176103.1
ENSMUST00000167458.2
Hbp1


high mobility group box transcription factor 1


chr5_+_64812336 1.395 ENSMUST00000166409.1
Klf3
Kruppel-like factor 3 (basic)
chrX_+_159840463 1.395 ENSMUST00000112451.1
ENSMUST00000112453.2
Sh3kbp1

SH3-domain kinase binding protein 1

chr11_-_102556122 1.388 ENSMUST00000143842.1
Gpatch8
G patch domain containing 8
chr4_-_59549243 1.379 ENSMUST00000173699.1
ENSMUST00000173884.1
ENSMUST00000102883.4
ENSMUST00000174586.1
Ptbp3



polypyrimidine tract binding protein 3



chr8_+_20136455 1.379 ENSMUST00000179299.1
ENSMUST00000096485.4
Gm21811

predicted gene, 21811

chr3_+_138860489 1.368 ENSMUST00000121826.1
Tspan5
tetraspanin 5
chr1_-_64121456 1.358 ENSMUST00000142009.1
ENSMUST00000114086.1
Klf7

Kruppel-like factor 7 (ubiquitous)

chr2_-_66440753 1.348 ENSMUST00000112371.2
ENSMUST00000138910.1
Scn1a

sodium channel, voltage-gated, type I, alpha

chr17_-_51810866 1.343 ENSMUST00000176669.1
Satb1
special AT-rich sequence binding protein 1
chr13_+_76579670 1.341 ENSMUST00000126960.1
ENSMUST00000109583.2
Mctp1

multiple C2 domains, transmembrane 1

chr11_+_3330781 1.340 ENSMUST00000136536.1
ENSMUST00000093399.4
Pik3ip1

phosphoinositide-3-kinase interacting protein 1

chr4_+_97772734 1.339 ENSMUST00000152023.1
Nfia
nuclear factor I/A
chr17_+_35077080 1.338 ENSMUST00000172959.1
Ly6g6e
lymphocyte antigen 6 complex, locus G6E
chr6_-_137169710 1.334 ENSMUST00000117919.1
Rerg
RAS-like, estrogen-regulated, growth-inhibitor
chr17_+_70522149 1.320 ENSMUST00000140728.1
Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr19_-_42086338 1.318 ENSMUST00000051772.8
Morn4
MORN repeat containing 4
chr18_+_77938452 1.299 ENSMUST00000044622.5
Epg5
ectopic P-granules autophagy protein 5 homolog (C. elegans)
chr10_+_69534039 1.296 ENSMUST00000182557.1
Ank3
ankyrin 3, epithelial
chr10_+_79716588 1.290 ENSMUST00000099513.1
ENSMUST00000020581.2
Hcn2

hyperpolarization-activated, cyclic nucleotide-gated K+ 2

chr9_-_42461414 1.277 ENSMUST00000066179.7
Tbcel
tubulin folding cofactor E-like
chr8_-_64205970 1.275 ENSMUST00000066166.4
Tll1
tolloid-like
chr14_-_55106547 1.274 ENSMUST00000036041.8
Ap1g2
adaptor protein complex AP-1, gamma 2 subunit
chr1_-_133753681 1.271 ENSMUST00000125659.1
ENSMUST00000165602.2
ENSMUST00000048953.7
Atp2b4


ATPase, Ca++ transporting, plasma membrane 4


chr17_+_55445375 1.257 ENSMUST00000133899.1
ENSMUST00000086878.3
St6gal2

beta galactoside alpha 2,6 sialyltransferase 2

chr2_+_176236860 1.253 ENSMUST00000166464.1
2210418O10Rik
RIKEN cDNA 2210418O10 gene
chr3_+_65109343 1.252 ENSMUST00000159525.1
ENSMUST00000049230.8
Kcnab1

potassium voltage-gated channel, shaker-related subfamily, beta member 1

chr1_-_179546261 1.251 ENSMUST00000027769.5
Tfb2m
transcription factor B2, mitochondrial
chr16_-_34262945 1.246 ENSMUST00000114953.1
Kalrn
kalirin, RhoGEF kinase
chr1_-_180195981 1.245 ENSMUST00000027766.6
ENSMUST00000161814.1
Adck3

aarF domain containing kinase 3

chr13_+_60602182 1.232 ENSMUST00000044083.7
Dapk1
death associated protein kinase 1
chr7_+_113207465 1.211 ENSMUST00000047321.7
Arntl
aryl hydrocarbon receptor nuclear translocator-like
chr7_-_12422751 1.209 ENSMUST00000080348.5
Zfp551
zinc fingr protein 551
chr8_-_3279606 1.205 ENSMUST00000091291.4
Insr
insulin receptor
chr11_+_75531690 1.205 ENSMUST00000149727.1
ENSMUST00000042561.7
ENSMUST00000108433.1
ENSMUST00000143035.1
Slc43a2



solute carrier family 43, member 2



chr16_-_97170707 1.186 ENSMUST00000056102.7
Dscam
Down syndrome cell adhesion molecule
chr2_+_128126030 1.185 ENSMUST00000089634.5
ENSMUST00000019281.7
ENSMUST00000110341.2
ENSMUST00000103211.1
ENSMUST00000103210.1
Bcl2l11




BCL2-like 11 (apoptosis facilitator)




chr11_+_78499087 1.183 ENSMUST00000017488.4
Vtn
vitronectin
chr11_-_121388186 1.183 ENSMUST00000106107.2
Rab40b
Rab40b, member RAS oncogene family
chr3_-_144202300 1.174 ENSMUST00000121796.1
ENSMUST00000121112.1
Lmo4

LIM domain only 4

chr4_-_45012093 1.172 ENSMUST00000131991.1
Zbtb5
zinc finger and BTB domain containing 5
chr5_+_122643878 1.171 ENSMUST00000100737.3
ENSMUST00000121489.1
ENSMUST00000031425.8
ENSMUST00000086247.5
P2rx7



purinergic receptor P2X, ligand-gated ion channel, 7



chr12_-_85270564 1.163 ENSMUST00000019378.6
ENSMUST00000166821.1
Mlh3

mutL homolog 3 (E coli)

chr7_+_19359740 1.152 ENSMUST00000140836.1
Ppp1r13l
protein phosphatase 1, regulatory (inhibitor) subunit 13 like
chr6_+_29853746 1.149 ENSMUST00000064872.6
ENSMUST00000152581.1
ENSMUST00000176265.1
ENSMUST00000154079.1
Ahcyl2



S-adenosylhomocysteine hydrolase-like 2



chr12_-_31950170 1.149 ENSMUST00000176520.1
Hbp1
high mobility group box transcription factor 1
chr5_-_103211251 1.145 ENSMUST00000060871.5
ENSMUST00000112846.1
ENSMUST00000170792.1
ENSMUST00000112847.2
Mapk10



mitogen-activated protein kinase 10



chr18_-_12121460 1.141 ENSMUST00000055447.6
ENSMUST00000050228.7
ENSMUST00000092075.4
Tmem241


transmembrane protein 241


chr16_+_43364145 1.141 ENSMUST00000148775.1
Zbtb20
zinc finger and BTB domain containing 20
chr14_+_55560904 1.140 ENSMUST00000072530.4
ENSMUST00000128490.1
Dcaf11

DDB1 and CUL4 associated factor 11

chr6_+_34709610 1.129 ENSMUST00000031775.6
Cald1
caldesmon 1
chr11_+_70214105 1.129 ENSMUST00000094055.3
ENSMUST00000136328.1
ENSMUST00000126296.1
ENSMUST00000153993.2
Slc16a11



solute carrier family 16 (monocarboxylic acid transporters), member 11



chr6_+_92940572 1.120 ENSMUST00000181145.1
ENSMUST00000181840.1
9530026P05Rik

RIKEN cDNA 9530026P05 gene

chr13_+_29016267 1.111 ENSMUST00000140415.1
A330102I10Rik
RIKEN cDNA A330102I10 gene
chr18_+_69593361 1.110 ENSMUST00000114978.2
ENSMUST00000114977.1
Tcf4

transcription factor 4

chrX_-_7740206 1.109 ENSMUST00000128289.1
Ccdc120
coiled-coil domain containing 120
chr10_-_105574435 1.109 ENSMUST00000061506.8
Tmtc2
transmembrane and tetratricopeptide repeat containing 2
chr16_+_94425083 1.102 ENSMUST00000141176.1
Ttc3
tetratricopeptide repeat domain 3
chr14_-_93888732 1.096 ENSMUST00000068992.2
Pcdh9
protocadherin 9
chr10_-_82690608 1.096 ENSMUST00000065815.6
ENSMUST00000020485.3
Glt8d2

glycosyltransferase 8 domain containing 2

chr9_+_96196246 1.096 ENSMUST00000165120.2
ENSMUST00000034982.9
Tfdp2

transcription factor Dp 2

chr5_+_14025305 1.087 ENSMUST00000073957.6
Sema3e
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr11_+_77765588 1.085 ENSMUST00000164315.1
Myo18a
myosin XVIIIA
chr16_-_74411292 1.082 ENSMUST00000117200.1
Robo2
roundabout homolog 2 (Drosophila)
chr11_+_107547925 1.078 ENSMUST00000100305.1
ENSMUST00000075012.1
ENSMUST00000106746.1
Helz


helicase with zinc finger domain


chr7_-_4844665 1.078 ENSMUST00000066041.5
ENSMUST00000172377.1
Shisa7

shisa homolog 7 (Xenopus laevis)

chr7_-_44849075 1.074 ENSMUST00000047085.8
Tbc1d17
TBC1 domain family, member 17
chr3_+_109573907 1.073 ENSMUST00000106576.2
Vav3
vav 3 oncogene
chr4_+_101507855 1.051 ENSMUST00000038207.5
Dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr3_+_76075583 1.043 ENSMUST00000160261.1
Fstl5
follistatin-like 5
chr2_+_112284561 1.029 ENSMUST00000053666.7
Slc12a6
solute carrier family 12, member 6
chr2_-_7396192 1.028 ENSMUST00000137733.2
Celf2
CUGBP, Elav-like family member 2
chr12_-_31950535 1.027 ENSMUST00000172314.2
Hbp1
high mobility group box transcription factor 1
chr16_-_63864114 1.021 ENSMUST00000064405.6
Epha3
Eph receptor A3
chr9_-_103230415 1.016 ENSMUST00000035158.9
Trf
transferrin
chr2_-_52558539 1.002 ENSMUST00000102760.3
ENSMUST00000102761.2
Cacnb4

calcium channel, voltage-dependent, beta 4 subunit

chr2_+_32095518 0.999 ENSMUST00000057423.5
Ppapdc3
phosphatidic acid phosphatase type 2 domain containing 3
chr7_+_130692532 0.993 ENSMUST00000033141.6
Tacc2
transforming, acidic coiled-coil containing protein 2
chr13_-_98815408 0.982 ENSMUST00000040340.8
ENSMUST00000099277.4
ENSMUST00000179563.1
ENSMUST00000109403.1
Fcho2



FCH domain only 2



chr11_+_3330401 0.972 ENSMUST00000045153.4
Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr16_-_4880284 0.972 ENSMUST00000037843.6
Ubald1
UBA-like domain containing 1
chr2_+_68117713 0.967 ENSMUST00000112346.2
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chrX_+_94234921 0.967 ENSMUST00000113908.1
ENSMUST00000113916.3
Klhl15

kelch-like 15

chr7_+_24907618 0.954 ENSMUST00000151121.1
Arhgef1
Rho guanine nucleotide exchange factor (GEF) 1
chr2_-_77519565 0.931 ENSMUST00000111830.2
Zfp385b
zinc finger protein 385B
chr10_+_39732099 0.924 ENSMUST00000019986.6
Rev3l
REV3-like, catalytic subunit of DNA polymerase zeta RAD54 like (S. cerevisiae)
chr1_+_180101144 0.924 ENSMUST00000133890.1
Cdc42bpa
CDC42 binding protein kinase alpha
chr14_-_55116935 0.923 ENSMUST00000022819.5
Jph4
junctophilin 4
chr19_+_26623419 0.913 ENSMUST00000176584.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.1 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
1.7 18.5 GO:0042572 retinol metabolic process(GO:0042572)
1.3 3.9 GO:0043379 rRNA export from nucleus(GO:0006407) memory T cell differentiation(GO:0043379) response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
1.3 3.8 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
1.2 8.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
1.1 4.4 GO:0002069 columnar/cuboidal epithelial cell maturation(GO:0002069)
1.0 2.9 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.9 3.5 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.8 2.4 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.6 3.2 GO:2000481 positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
0.6 1.9 GO:0099547 regulation of translation at synapse, modulating synaptic transmission(GO:0099547) regulation of translation at postsynapse, modulating synaptic transmission(GO:0099578) positive regulation of intracellular transport of viral material(GO:1901254)
0.6 2.5 GO:0055099 response to high density lipoprotein particle(GO:0055099) platelet dense granule organization(GO:0060155)
0.6 3.1 GO:0097167 circadian regulation of translation(GO:0097167)
0.6 1.8 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.6 3.0 GO:0046684 response to pyrethroid(GO:0046684)
0.6 1.8 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.6 2.9 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.6 1.7 GO:0002159 desmosome assembly(GO:0002159)
0.6 1.7 GO:0090327 negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.5 3.8 GO:0035826 rubidium ion transport(GO:0035826) cellular hypotonic response(GO:0071476)
0.5 10.3 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.5 4.3 GO:0060137 maternal process involved in parturition(GO:0060137)
0.5 7.6 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.5 2.0 GO:0035470 positive regulation of vascular wound healing(GO:0035470)
0.5 1.5 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.5 1.5 GO:1901894 regulation of calcium-transporting ATPase activity(GO:1901894)
0.5 2.8 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.4 3.6 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.4 3.8 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.4 3.7 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.4 1.2 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.4 2.7 GO:0033227 dsRNA transport(GO:0033227)
0.4 6.3 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.4 1.2 GO:0032650 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) interleukin-1 alpha secretion(GO:0050703) regulation of bleb assembly(GO:1904170)
0.4 5.0 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.4 1.1 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.4 0.7 GO:0034239 regulation of macrophage fusion(GO:0034239)
0.4 4.6 GO:0070842 aggresome assembly(GO:0070842)
0.4 3.9 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.3 3.8 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.3 2.1 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.3 1.0 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.3 3.6 GO:0042118 endothelial cell activation(GO:0042118)
0.3 1.3 GO:0070305 response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321)
0.3 1.6 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.3 1.5 GO:0051684 maintenance of Golgi location(GO:0051684)
0.3 1.2 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139) apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.3 1.4 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.3 1.4 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.3 0.8 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.3 1.4 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.3 0.8 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.3 2.5 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.3 3.0 GO:0097421 liver regeneration(GO:0097421)
0.3 4.9 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.3 1.1 GO:1903028 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.3 2.4 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.3 1.0 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.2 1.0 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.2 3.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.2 0.7 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.2 0.7 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.2 1.6 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.2 2.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.2 1.1 GO:0072530 purine-containing compound transmembrane transport(GO:0072530)
0.2 2.5 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.2 0.7 GO:0045575 basophil activation involved in immune response(GO:0002276) basophil activation(GO:0045575)
0.2 0.7 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.2 1.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.2 0.6 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.2 1.2 GO:0007144 female meiosis I(GO:0007144)
0.2 1.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.2 1.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.2 1.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.2 0.9 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.2 4.1 GO:0008090 retrograde axonal transport(GO:0008090)
0.2 0.9 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.2 0.9 GO:0002317 plasma cell differentiation(GO:0002317)
0.2 0.5 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.2 1.2 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.2 1.3 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.2 0.8 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.2 1.3 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.2 0.9 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.2 2.3 GO:0035988 chondrocyte proliferation(GO:0035988)
0.1 1.8 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1 1.5 GO:0071455 cellular response to hyperoxia(GO:0071455) cellular response to nitric oxide(GO:0071732)
0.1 5.7 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.1 0.4 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 1.9 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 0.8 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.1 0.8 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.1 1.0 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 1.0 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 0.4 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.3 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.1 0.1 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.1 1.8 GO:0030953 astral microtubule organization(GO:0030953)
0.1 0.3 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.1 1.0 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.5 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) regulation of follicle-stimulating hormone secretion(GO:0046880) follicle-stimulating hormone secretion(GO:0046884) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.1 0.6 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.1 0.1 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.1 0.7 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.1 0.7 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.1 0.7 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.1 0.9 GO:0090166 Golgi disassembly(GO:0090166)
0.1 3.3 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.1 2.9 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.1 0.4 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.1 0.4 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.1 1.4 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 1.4 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.1 0.5 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 0.3 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.1 0.5 GO:2001015 skeletal muscle satellite cell activation(GO:0014719) optic nerve morphogenesis(GO:0021631) negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.1 0.9 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.5 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 0.3 GO:0030473 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473) nuclear migration along microfilament(GO:0031022)
0.1 0.2 GO:0010920 negative regulation of inositol phosphate biosynthetic process(GO:0010920)
0.1 3.3 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 0.6 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 1.7 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 1.3 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 1.2 GO:0072189 ureter development(GO:0072189)
0.1 0.6 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.1 1.2 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.1 0.4 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.1 0.4 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.8 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 1.2 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.1 1.5 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.9 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.5 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 0.2 GO:0021972 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) corticospinal neuron axon guidance(GO:0021966) corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.1 0.8 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 0.2 GO:0070343 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
0.1 0.5 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.1 0.3 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 0.4 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.4 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 0.2 GO:0090298 negative regulation of mitochondrial DNA replication(GO:0090298)
0.1 0.6 GO:0034776 response to histamine(GO:0034776) cellular response to histamine(GO:0071420)
0.1 1.3 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.1 0.3 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.3 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 1.6 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.9 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 1.1 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.1 0.1 GO:1900623 positive regulation of keratinocyte proliferation(GO:0010838) regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 1.2 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.1 0.7 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.2 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 0.7 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 2.1 GO:0050919 negative chemotaxis(GO:0050919)
0.1 0.9 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1 2.7 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.1 4.7 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.1 0.6 GO:0007220 Notch receptor processing(GO:0007220) skin morphogenesis(GO:0043589)
0.1 0.5 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 0.6 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.1 0.9 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 0.2 GO:0032306 regulation of prostaglandin secretion(GO:0032306) positive regulation of prostaglandin secretion(GO:0032308)
0.1 0.5 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.1 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.7 GO:0015809 arginine transport(GO:0015809)
0.0 0.7 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 3.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.6 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 0.5 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.1 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.4 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.5 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.2 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.0 0.2 GO:0034773 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.0 0.2 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.2 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.4 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.0 1.0 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 1.3 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.2 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0 0.4 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 1.0 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.7 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.7 GO:0061157 mRNA destabilization(GO:0061157)
0.0 0.1 GO:0090472 dibasic protein processing(GO:0090472)
0.0 0.4 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.4 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.3 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.3 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.1 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.0 1.7 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.1 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.0 0.2 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.8 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.1 GO:2000642 negative regulation of vacuolar transport(GO:1903336) negative regulation of early endosome to late endosome transport(GO:2000642)
0.0 1.0 GO:0008542 visual learning(GO:0008542)
0.0 0.4 GO:0051084 'de novo' posttranslational protein folding(GO:0051084)
0.0 0.2 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.1 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 2.5 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.2 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 1.9 GO:0007416 synapse assembly(GO:0007416)
0.0 0.1 GO:0015879 carnitine transport(GO:0015879)
0.0 0.5 GO:0050806 positive regulation of synaptic transmission(GO:0050806)
0.0 0.1 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.1 GO:0006048 glucosamine metabolic process(GO:0006041) UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.3 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.1 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.8 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.1 GO:0006953 acute-phase response(GO:0006953)
0.0 0.1 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.1 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.5 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.4 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.3 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 0.2 GO:0019233 sensory perception of pain(GO:0019233)
0.0 0.3 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0033596 TSC1-TSC2 complex(GO:0033596)
1.2 4.9 GO:0044307 dendritic branch(GO:0044307)
1.0 4.1 GO:0031673 H zone(GO:0031673)
0.7 2.8 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.6 5.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.5 1.9 GO:1902737 viral replication complex(GO:0019034) dendritic filopodium(GO:1902737)
0.4 1.3 GO:0098855 HCN channel complex(GO:0098855)
0.4 1.2 GO:0005899 insulin receptor complex(GO:0005899)
0.3 11.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.3 1.0 GO:0098835 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.3 3.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.3 2.7 GO:0030478 actin cap(GO:0030478)
0.3 4.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.3 1.4 GO:1990130 Iml1 complex(GO:1990130)
0.3 3.5 GO:0030057 desmosome(GO:0030057)
0.3 1.3 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.2 4.9 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.2 0.7 GO:0016939 kinesin II complex(GO:0016939)
0.2 0.6 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.2 0.9 GO:0030314 junctional membrane complex(GO:0030314)
0.2 6.8 GO:0035861 site of double-strand break(GO:0035861)
0.2 1.8 GO:0071141 SMAD protein complex(GO:0071141)
0.2 3.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 0.5 GO:0043512 inhibin A complex(GO:0043512)
0.2 0.5 GO:0044753 amphisome(GO:0044753)
0.2 1.3 GO:0097433 dense body(GO:0097433)
0.2 0.9 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.2 1.7 GO:0000812 Swr1 complex(GO:0000812)
0.2 1.2 GO:0033391 chromatoid body(GO:0033391)
0.1 1.9 GO:1990635 proximal dendrite(GO:1990635)
0.1 3.1 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 2.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 0.8 GO:0035976 AP1 complex(GO:0035976)
0.1 2.5 GO:0071564 npBAF complex(GO:0071564)
0.1 1.2 GO:0032300 mismatch repair complex(GO:0032300)
0.1 1.9 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 1.3 GO:0032426 stereocilium tip(GO:0032426)
0.1 6.1 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 1.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 3.8 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 1.2 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 1.1 GO:0097542 ciliary tip(GO:0097542)
0.1 0.5 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.6 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.2 GO:0034657 GID complex(GO:0034657)
0.1 0.4 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 3.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 0.6 GO:0097227 sperm annulus(GO:0097227)
0.1 0.7 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 1.3 GO:0097228 sperm principal piece(GO:0097228)
0.1 1.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.9 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 0.4 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.1 3.3 GO:0031941 filamentous actin(GO:0031941)
0.1 3.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 0.4 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 0.5 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.1 1.7 GO:0030673 axolemma(GO:0030673)
0.0 0.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.7 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.3 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.6 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.7 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.5 GO:0045180 basal cortex(GO:0045180)
0.0 1.9 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.9 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.3 GO:0044327 dendritic spine head(GO:0044327)
0.0 11.0 GO:0014069 postsynaptic density(GO:0014069)
0.0 1.9 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 0.5 GO:0032433 filopodium tip(GO:0032433)
0.0 1.3 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 2.0 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.4 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 1.3 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 1.4 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.4 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.8 GO:0031201 SNARE complex(GO:0031201)
0.0 0.1 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 1.3 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 1.3 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.5 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 7.9 GO:0016607 nuclear speck(GO:0016607)
0.0 1.2 GO:0030667 secretory granule membrane(GO:0030667)
0.0 9.5 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 0.1 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 3.7 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.6 GO:0030139 endocytic vesicle(GO:0030139)
0.0 14.9 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 1.7 GO:0005814 centriole(GO:0005814)
0.0 0.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.7 GO:0005811 lipid particle(GO:0005811)
0.0 0.0 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
2.6 18.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
1.1 3.4 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
1.0 3.9 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
1.0 2.9 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.9 3.6 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.8 2.5 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.7 2.7 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.7 2.0 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.6 5.2 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.6 4.3 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.6 1.8 GO:0035500 MH2 domain binding(GO:0035500)
0.4 4.8 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.4 9.6 GO:0042287 MHC protein binding(GO:0042287)
0.4 3.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.4 3.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.4 1.8 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.3 6.8 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.3 1.3 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.3 1.3 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.3 1.6 GO:0004849 uridine kinase activity(GO:0004849)
0.3 0.9 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.3 1.2 GO:0019237 centromeric DNA binding(GO:0019237)
0.3 1.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.3 0.8 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.3 1.6 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.3 1.9 GO:0033592 RNA strand annealing activity(GO:0033592)
0.3 2.3 GO:0071253 connexin binding(GO:0071253)
0.3 2.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.3 1.3 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.2 1.0 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.2 1.2 GO:0051425 PTB domain binding(GO:0051425)
0.2 0.7 GO:0008502 melatonin receptor activity(GO:0008502)
0.2 2.8 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 0.7 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.2 0.7 GO:0005118 sevenless binding(GO:0005118)
0.2 4.3 GO:0031402 sodium ion binding(GO:0031402)
0.2 1.5 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.2 1.4 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2 1.2 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.2 0.8 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.2 1.3 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.2 0.7 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.2 0.9 GO:0042610 CD8 receptor binding(GO:0042610)
0.2 3.9 GO:0032794 GTPase activating protein binding(GO:0032794)
0.2 1.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 1.0 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.2 1.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.2 1.6 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.2 0.9 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.1 4.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.7 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 0.9 GO:0097001 ceramide binding(GO:0097001)
0.1 1.7 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.8 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 1.3 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.1 0.5 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 4.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 1.8 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 1.3 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 1.1 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.1 3.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 1.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.3 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 1.1 GO:0045499 chemorepellent activity(GO:0045499)
0.1 1.3 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.1 1.6 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.4 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.1 0.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 1.0 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.1 1.1 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.7 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 0.5 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 2.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 0.4 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.1 4.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 1.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.4 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.1 0.7 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.7 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 0.6 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 0.6 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.4 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 3.9 GO:0030507 spectrin binding(GO:0030507)
0.1 0.4 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 3.1 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 1.9 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 0.7 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 0.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 1.0 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 1.6 GO:0031690 adrenergic receptor binding(GO:0031690)
0.1 3.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.3 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.4 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 1.5 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.5 GO:0001846 opsonin binding(GO:0001846)
0.0 0.4 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.0 0.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 1.2 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0005124 scavenger receptor binding(GO:0005124)
0.0 0.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.2 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.9 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.5 GO:0035497 cAMP response element binding(GO:0035497)
0.0 2.1 GO:0003823 antigen binding(GO:0003823)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.4 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.9 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.3 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 1.1 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 2.1 GO:0002039 p53 binding(GO:0002039)
0.0 0.5 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.7 GO:0070064 proline-rich region binding(GO:0070064)
0.0 1.3 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 2.5 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)
0.0 0.8 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.1 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 1.9 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 0.1 GO:0098809 nitrite reductase activity(GO:0098809)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.4 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.6 GO:0043531 ADP binding(GO:0043531)
0.0 0.2 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 8.7 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.1 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 1.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0015093 iron ion transmembrane transporter activity(GO:0005381) ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.9 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.5 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.7 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.7 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.0 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.5 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.2 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.2 GO:0042165 neurotransmitter binding(GO:0042165)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 23.3 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 3.0 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.1 7.5 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 4.5 PID_IL3_PATHWAY IL3-mediated signaling events
0.1 7.7 PID_FOXO_PATHWAY FoxO family signaling
0.1 0.7 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.1 6.6 PID_LKB1_PATHWAY LKB1 signaling events
0.1 0.5 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 2.7 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.1 3.3 ST_ADRENERGIC Adrenergic Pathway
0.1 2.4 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.1 2.7 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.1 1.1 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.1 1.2 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.1 3.2 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 3.3 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.1 1.6 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.1 0.6 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.1 1.0 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.1 1.1 PID_E2F_PATHWAY E2F transcription factor network
0.0 1.2 PID_IFNG_PATHWAY IFN-gamma pathway
0.0 0.5 PID_INSULIN_PATHWAY Insulin Pathway
0.0 1.3 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 1.5 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.5 PID_TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.3 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.8 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.7 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.0 1.0 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.0 1.6 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 1.3 PID_CDC42_PATHWAY CDC42 signaling events
0.0 1.0 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 0.5 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.9 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
0.0 3.2 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.8 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 2.3 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 0.5 PID_IL1_PATHWAY IL1-mediated signaling events
0.0 4.2 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 0.1 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.4 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 0.2 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 0.3 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.4 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.9 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.3 4.0 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.3 5.5 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.3 3.1 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.3 2.8 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.2 1.0 REACTOME_G_ALPHA1213_SIGNALLING_EVENTS Genes involved in G alpha (12/13) signalling events
0.2 2.9 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.2 1.5 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.2 4.2 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.2 4.9 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.2 2.4 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.2 4.1 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 4.3 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 4.9 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 0.5 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.1 1.2 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.1 1.0 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 1.7 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.7 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 2.1 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.2 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 0.6 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 2.3 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 1.7 REACTOME_EARLY_PHASE_OF_HIV_LIFE_CYCLE Genes involved in Early Phase of HIV Life Cycle
0.1 1.1 REACTOME_NRIF_SIGNALS_CELL_DEATH_FROM_THE_NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.1 2.4 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 1.2 REACTOME_MEIOSIS Genes involved in Meiosis
0.1 1.2 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.1 0.5 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 1.6 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.6 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.4 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.1 1.4 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.7 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 1.5 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.5 REACTOME_ACTIVATION_OF_CHAPERONES_BY_ATF6_ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 1.2 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 3.8 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.2 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.6 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.0 1.1 REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.3 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.8 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.3 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.0 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.4 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.8 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.6 REACTOME_REGULATORY_RNA_PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.4 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.0 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.8 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.0 1.1 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.7 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.2 REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.1 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.1 REACTOME_TRAF6_MEDIATED_INDUCTION_OF_TAK1_COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 0.1 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.9 REACTOME_DNA_REPAIR Genes involved in DNA Repair
0.0 0.1 REACTOME_SIGNALING_BY_FGFR1_MUTANTS Genes involved in Signaling by FGFR1 mutants
0.0 0.4 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.2 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters