Motif ID: Foxm1

Z-value: 0.749


Transcription factors associated with Foxm1:

Gene SymbolEntrez IDGene Name
Foxm1 ENSMUSG00000001517.8 Foxm1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxm1mm10_v2_chr6_+_128362919_1283630580.095.7e-01Click!


Activity profile for motif Foxm1.

activity profile for motif Foxm1


Sorted Z-values histogram for motif Foxm1

Sorted Z-values for motif Foxm1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxm1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_138842429 5.033 ENSMUST00000112026.2
ENSMUST00000019374.7
Lhx9

LIM homeobox protein 9

chr15_+_98167806 3.524 ENSMUST00000031914.4
AI836003
expressed sequence AI836003
chr8_+_34807287 3.501 ENSMUST00000033930.4
Dusp4
dual specificity phosphatase 4
chrX_-_141725181 3.501 ENSMUST00000067841.7
Irs4
insulin receptor substrate 4
chr1_-_79440039 3.367 ENSMUST00000049972.4
Scg2
secretogranin II
chr2_+_65845833 3.343 ENSMUST00000053910.3
Csrnp3
cysteine-serine-rich nuclear protein 3
chr2_+_65845767 2.908 ENSMUST00000122912.1
Csrnp3
cysteine-serine-rich nuclear protein 3
chr10_-_130280218 2.596 ENSMUST00000061571.3
Neurod4
neurogenic differentiation 4
chr4_-_36136463 2.515 ENSMUST00000098151.2
Lingo2
leucine rich repeat and Ig domain containing 2
chr8_+_58912257 2.114 ENSMUST00000160055.1
BC030500
cDNA sequence BC030500
chr3_+_134828993 2.075 ENSMUST00000029822.4
Tacr3
tachykinin receptor 3
chr19_-_58455161 1.871 ENSMUST00000135730.1
ENSMUST00000152507.1
Gfra1

glial cell line derived neurotrophic factor family receptor alpha 1

chr18_-_62741387 1.751 ENSMUST00000097557.3
Spink13
serine peptidase inhibitor, Kazal type 13
chr19_+_25672408 1.615 ENSMUST00000053068.5
Dmrt2
doublesex and mab-3 related transcription factor 2
chr2_+_136052180 1.594 ENSMUST00000144403.1
Lamp5
lysosomal-associated membrane protein family, member 5
chr19_-_58455903 1.576 ENSMUST00000131877.1
Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr19_-_58455398 1.490 ENSMUST00000026076.7
Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr10_+_127421208 1.392 ENSMUST00000168780.1
R3hdm2
R3H domain containing 2
chr17_+_34305883 1.370 ENSMUST00000074557.8
H2-Eb1
histocompatibility 2, class II antigen E beta
chr10_+_112928501 1.284 ENSMUST00000180464.1
Gm26596
predicted gene, 26596
chr7_+_83755904 1.279 ENSMUST00000051522.8
ENSMUST00000042280.7
Gm7964

predicted gene 7964

chr18_+_36952621 1.219 ENSMUST00000115661.2
Pcdha2
protocadherin alpha 2
chr16_-_32165454 1.216 ENSMUST00000115163.3
ENSMUST00000144345.1
ENSMUST00000143682.1
ENSMUST00000115165.3
ENSMUST00000099991.4
ENSMUST00000130410.1
Nrros





negative regulator of reactive oxygen species





chrX_+_164373363 1.165 ENSMUST00000033751.7
Figf
c-fos induced growth factor
chr15_+_102459028 1.159 ENSMUST00000164938.1
ENSMUST00000023810.5
Prr13

proline rich 13

chr2_+_104095796 1.135 ENSMUST00000040423.5
ENSMUST00000168176.1
Cd59a

CD59a antigen

chr15_+_102460076 1.123 ENSMUST00000164688.1
Prr13
proline rich 13
chr2_+_138278481 1.088 ENSMUST00000075410.4
Btbd3
BTB (POZ) domain containing 3
chrX_-_56598069 1.065 ENSMUST00000059899.2
Mmgt1
membrane magnesium transporter 1
chr4_+_63544747 1.029 ENSMUST00000035301.6
Atp6v1g1
ATPase, H+ transporting, lysosomal V1 subunit G1
chr11_-_3266377 0.941 ENSMUST00000020741.5
Drg1
developmentally regulated GTP binding protein 1
chr7_-_19921139 0.930 ENSMUST00000043517.7
Pvr
poliovirus receptor
chr11_-_42000284 0.929 ENSMUST00000109292.2
ENSMUST00000109290.1
Gabrg2

gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2

chr7_+_31059342 0.922 ENSMUST00000039775.7
Lgi4
leucine-rich repeat LGI family, member 4
chr10_+_94576254 0.921 ENSMUST00000117929.1
Tmcc3
transmembrane and coiled coil domains 3
chr2_-_32424005 0.908 ENSMUST00000113307.2
Slc25a25
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25
chr9_-_100571049 0.897 ENSMUST00000093792.2
Slc35g2
solute carrier family 35, member G2
chr3_+_76075583 0.883 ENSMUST00000160261.1
Fstl5
follistatin-like 5
chr5_-_103211251 0.879 ENSMUST00000060871.5
ENSMUST00000112846.1
ENSMUST00000170792.1
ENSMUST00000112847.2
Mapk10



mitogen-activated protein kinase 10



chr12_-_40037387 0.864 ENSMUST00000146905.1
Arl4a
ADP-ribosylation factor-like 4A
chr6_+_142387215 0.860 ENSMUST00000032372.6
Golt1b
golgi transport 1 homolog B (S. cerevisiae)
chr11_-_42000532 0.841 ENSMUST00000070735.3
Gabrg2
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr1_+_74713551 0.835 ENSMUST00000027356.5
Cyp27a1
cytochrome P450, family 27, subfamily a, polypeptide 1
chr9_-_75597643 0.789 ENSMUST00000164100.1
Tmod2
tropomodulin 2
chr2_+_68117713 0.746 ENSMUST00000112346.2
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr15_+_102459193 0.732 ENSMUST00000164957.1
ENSMUST00000171245.1
Prr13

proline rich 13

chr5_-_24581879 0.714 ENSMUST00000088299.4
Gm10221
predicted gene 10221
chr7_-_133123770 0.714 ENSMUST00000164896.1
ENSMUST00000171968.1
Ctbp2

C-terminal binding protein 2

chrX_-_75578188 0.710 ENSMUST00000033545.5
Rab39b
RAB39B, member RAS oncogene family
chr8_-_22653406 0.706 ENSMUST00000033938.5
Polb
polymerase (DNA directed), beta
chr9_-_121839460 0.705 ENSMUST00000135986.2
Ccdc13
coiled-coil domain containing 13
chr2_-_152831665 0.699 ENSMUST00000156688.1
ENSMUST00000007803.5
Bcl2l1

BCL2-like 1

chr6_-_59024340 0.694 ENSMUST00000173193.1
Fam13a
family with sequence similarity 13, member A
chr10_+_127421124 0.685 ENSMUST00000170336.1
R3hdm2
R3H domain containing 2
chr4_-_44710408 0.677 ENSMUST00000134968.2
ENSMUST00000173821.1
ENSMUST00000174319.1
ENSMUST00000173733.1
ENSMUST00000172866.1
ENSMUST00000165417.2
ENSMUST00000107825.2
ENSMUST00000102932.3
ENSMUST00000107827.2
ENSMUST00000107826.2
Pax5









paired box gene 5









chr4_+_143413002 0.676 ENSMUST00000155157.1
Pramef8
PRAME family member 8
chr5_-_125390176 0.672 ENSMUST00000156249.1
Ubc
ubiquitin C
chr5_+_137553517 0.658 ENSMUST00000136088.1
ENSMUST00000139395.1
ENSMUST00000136565.1
ENSMUST00000149292.1
ENSMUST00000125489.1
Actl6b




actin-like 6B




chr6_-_148944750 0.651 ENSMUST00000111562.1
ENSMUST00000081956.5
Fam60a

family with sequence similarity 60, member A

chrX_+_9885622 0.649 ENSMUST00000067529.2
ENSMUST00000086165.3
Sytl5

synaptotagmin-like 5

chr2_-_165852149 0.641 ENSMUST00000109258.3
Zmynd8
zinc finger, MYND-type containing 8
chr4_+_155522462 0.639 ENSMUST00000177094.1
Gnb1
guanine nucleotide binding protein (G protein), beta 1
chr1_+_89454769 0.637 ENSMUST00000027521.8
ENSMUST00000074945.5
Agap1

ArfGAP with GTPase domain, ankyrin repeat and PH domain 1

chr6_-_142386974 0.627 ENSMUST00000129694.1
Recql
RecQ protein-like
chr10_-_81230773 0.607 ENSMUST00000047408.4
Atcay
ataxia, cerebellar, Cayman type homolog (human)
chr13_+_55209776 0.600 ENSMUST00000099490.2
Nsd1
nuclear receptor-binding SET-domain protein 1
chr5_-_87490869 0.570 ENSMUST00000147854.1
Ugt2a1
UDP glucuronosyltransferase 2 family, polypeptide A1
chr12_-_80760541 0.568 ENSMUST00000073251.6
Ccdc177
coiled-coil domain containing 177
chrM_+_5319 0.558 ENSMUST00000082402.1
mt-Co1
mitochondrially encoded cytochrome c oxidase I
chr8_-_36732897 0.557 ENSMUST00000098826.3
Dlc1
deleted in liver cancer 1
chr7_-_30072801 0.548 ENSMUST00000183115.1
ENSMUST00000182919.1
ENSMUST00000183190.1
ENSMUST00000080834.8
Zfp82



zinc finger protein 82



chr1_-_75142360 0.546 ENSMUST00000041213.5
Cnppd1
cyclin Pas1/PHO80 domain containing 1
chr4_-_141790891 0.531 ENSMUST00000038014.4
ENSMUST00000153880.1
Dnajc16

DnaJ (Hsp40) homolog, subfamily C, member 16

chr6_-_122340499 0.527 ENSMUST00000160843.1
Phc1
polyhomeotic-like 1 (Drosophila)
chrX_+_38600626 0.516 ENSMUST00000000365.2
Mcts1
malignant T cell amplified sequence 1
chr12_-_99393010 0.513 ENSMUST00000177451.1
Foxn3
forkhead box N3
chr7_-_126566364 0.502 ENSMUST00000032992.5
Eif3c
eukaryotic translation initiation factor 3, subunit C
chr10_-_49783259 0.475 ENSMUST00000105484.3
ENSMUST00000105486.1
ENSMUST00000079751.2
ENSMUST00000105485.1
Grik2



glutamate receptor, ionotropic, kainate 2 (beta 2)



chr13_+_43370710 0.463 ENSMUST00000066804.4
Sirt5
sirtuin 5
chr6_+_142413441 0.452 ENSMUST00000088263.4
B230216G23Rik
RIKEN cDNA B230216G23 gene
chr2_+_10372426 0.452 ENSMUST00000114864.2
ENSMUST00000116594.2
ENSMUST00000041105.6
Sfmbt2


Scm-like with four mbt domains 2


chr14_+_73173825 0.437 ENSMUST00000166875.1
Rcbtb2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr4_+_143412920 0.431 ENSMUST00000132915.1
ENSMUST00000037356.7
Pramef8

PRAME family member 8

chr8_-_41417042 0.423 ENSMUST00000033999.6
Frg1
FSHD region gene 1
chr6_-_142387035 0.409 ENSMUST00000032370.6
ENSMUST00000100832.3
ENSMUST00000128082.1
ENSMUST00000111803.2
Recql



RecQ protein-like



chr7_-_28949670 0.403 ENSMUST00000148196.1
Actn4
actinin alpha 4
chr18_-_66022580 0.402 ENSMUST00000143990.1
Lman1
lectin, mannose-binding, 1
chr7_-_133123409 0.395 ENSMUST00000170459.1
ENSMUST00000166400.1
Ctbp2

C-terminal binding protein 2

chr6_+_142414012 0.377 ENSMUST00000141548.1
B230216G23Rik
RIKEN cDNA B230216G23 gene
chr11_+_94044111 0.377 ENSMUST00000132079.1
Spag9
sperm associated antigen 9
chr14_-_24486994 0.357 ENSMUST00000026322.7
Polr3a
polymerase (RNA) III (DNA directed) polypeptide A
chr14_-_5455467 0.351 ENSMUST00000180867.1
Gm3194
predicted gene 3194
chr11_+_74770822 0.337 ENSMUST00000141755.1
ENSMUST00000010698.6
Mettl16

methyltransferase like 16

chr6_+_142413833 0.330 ENSMUST00000126521.2
B230216G23Rik
RIKEN cDNA B230216G23 gene
chr3_-_28765364 0.323 ENSMUST00000094335.3
Gm6505
predicted pseudogene 6505
chr11_-_78183551 0.319 ENSMUST00000102483.4
Rpl23a
ribosomal protein L23A
chr10_+_90829780 0.317 ENSMUST00000179337.2
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr3_+_106113229 0.314 ENSMUST00000079132.5
ENSMUST00000139086.1
Chia

chitinase, acidic

chr5_-_31526693 0.310 ENSMUST00000118874.1
ENSMUST00000117642.1
ENSMUST00000065388.4
Supt7l


suppressor of Ty 7-like


chr18_-_20682963 0.282 ENSMUST00000165229.2
Gm10269
predicted gene 10269
chr8_-_47713920 0.276 ENSMUST00000038738.5
Cdkn2aip
CDKN2A interacting protein
chr5_-_140321524 0.270 ENSMUST00000031534.6
Mad1l1
MAD1 mitotic arrest deficient 1-like 1
chr6_-_122340525 0.269 ENSMUST00000112600.2
Phc1
polyhomeotic-like 1 (Drosophila)
chr3_-_95357156 0.268 ENSMUST00000107171.3
ENSMUST00000015841.5
ENSMUST00000107170.2
Setdb1


SET domain, bifurcated 1


chr10_+_11281583 0.250 ENSMUST00000070300.4
Fbxo30
F-box protein 30
chrX_+_112311334 0.248 ENSMUST00000026599.3
ENSMUST00000113415.1
Apool

apolipoprotein O-like

chr4_-_120951664 0.237 ENSMUST00000106280.1
Zfp69
zinc finger protein 69
chr12_+_3365108 0.227 ENSMUST00000020999.5
Kif3c
kinesin family member 3C
chr3_-_106167564 0.215 ENSMUST00000063062.8
Chi3l3
chitinase 3-like 3
chr2_-_132247623 0.214 ENSMUST00000110164.1
Tmem230
transmembrane protein 230
chr13_-_23934156 0.201 ENSMUST00000052776.2
Hist1h2ba
histone cluster 1, H2ba
chr10_-_63927434 0.199 ENSMUST00000079279.3
Gm10118
predicted gene 10118
chr9_+_109931458 0.199 ENSMUST00000072772.5
ENSMUST00000035055.8
Map4

microtubule-associated protein 4

chr6_-_71823805 0.195 ENSMUST00000065103.2
Mrpl35
mitochondrial ribosomal protein L35
chr9_-_71163224 0.182 ENSMUST00000074465.2
Aqp9
aquaporin 9
chr19_-_7019423 0.176 ENSMUST00000040772.8
Fermt3
fermitin family homolog 3 (Drosophila)
chr16_-_10447340 0.172 ENSMUST00000051118.6
Tvp23a
trans-golgi network vesicle protein 23A
chr1_+_171331414 0.157 ENSMUST00000097467.1
Dedd
death effector domain-containing
chr10_+_90829835 0.153 ENSMUST00000179964.1
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr15_+_36174010 0.153 ENSMUST00000180159.1
ENSMUST00000057177.6
Polr2k

polymerase (RNA) II (DNA directed) polypeptide K

chr7_+_19382005 0.145 ENSMUST00000062831.9
ENSMUST00000108461.1
ENSMUST00000108460.1
Ercc2


excision repair cross-complementing rodent repair deficiency, complementation group 2


chr12_+_98628126 0.144 ENSMUST00000048402.5
ENSMUST00000101144.3
ENSMUST00000101146.3
Spata7


spermatogenesis associated 7


chr1_+_75142775 0.140 ENSMUST00000097694.4
Fam134a
family with sequence similarity 134, member A
chr6_-_13871459 0.131 ENSMUST00000155856.1
2610001J05Rik
RIKEN cDNA 2610001J05 gene
chr10_+_11281304 0.129 ENSMUST00000129456.1
Fbxo30
F-box protein 30
chr8_-_54529951 0.125 ENSMUST00000067476.8
Spcs3
signal peptidase complex subunit 3 homolog (S. cerevisiae)
chr12_-_51971289 0.119 ENSMUST00000040583.5
Heatr5a
HEAT repeat containing 5A
chr12_+_76072016 0.118 ENSMUST00000131480.1
Syne2
spectrin repeat containing, nuclear envelope 2
chr15_+_79690869 0.107 ENSMUST00000046463.8
Gtpbp1
GTP binding protein 1
chr7_-_83550258 0.099 ENSMUST00000177929.1
Gm10610
predicted gene 10610
chr4_-_117891994 0.099 ENSMUST00000030265.3
Dph2
DPH2 homolog (S. cerevisiae)
chr13_-_100650981 0.094 ENSMUST00000022136.6
ENSMUST00000177848.1
Rad17

RAD17 homolog (S. pombe)

chr7_+_82611777 0.091 ENSMUST00000172784.1
Adamtsl3
ADAMTS-like 3
chr11_-_96075581 0.089 ENSMUST00000107686.1
ENSMUST00000107684.1
Atp5g1

ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9)

chr1_+_158362261 0.087 ENSMUST00000046110.9
Astn1
astrotactin 1
chr6_-_13871477 0.081 ENSMUST00000139231.1
2610001J05Rik
RIKEN cDNA 2610001J05 gene
chr11_-_97996171 0.080 ENSMUST00000042971.9
Arl5c
ADP-ribosylation factor-like 5C
chr11_-_34833631 0.075 ENSMUST00000093191.2
Spdl1
spindle apparatus coiled-coil protein 1
chr5_+_145140362 0.073 ENSMUST00000162594.1
ENSMUST00000162308.1
ENSMUST00000159018.1
ENSMUST00000160075.1
Bud31



BUD31 homolog (yeast)



chr10_-_116972609 0.065 ENSMUST00000092165.4
Gm10271
predicted gene 10271
chr2_+_131210363 0.054 ENSMUST00000110210.1
ENSMUST00000089506.5
ENSMUST00000110208.1
Ap5s1


adaptor-related protein 5 complex, sigma 1 subunit


chr11_-_110168073 0.049 ENSMUST00000044850.3
Abca9
ATP-binding cassette, sub-family A (ABC1), member 9
chr9_+_107580117 0.009 ENSMUST00000093785.4
Nat6
N-acetyltransferase 6
chr17_-_87025353 0.007 ENSMUST00000024957.6
Pigf
phosphatidylinositol glycan anchor biosynthesis, class F
chr7_-_103741322 0.004 ENSMUST00000051346.2
Olfr629
olfactory receptor 629

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.0 GO:0035262 gonad morphogenesis(GO:0035262)
0.7 3.4 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.4 1.6 GO:0061055 myotome development(GO:0061055)
0.4 1.8 GO:0060467 negative regulation of fertilization(GO:0060467)
0.3 0.9 GO:0002423 natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.3 2.1 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.2 0.7 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.2 3.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.2 0.6 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
0.2 2.6 GO:0035881 amacrine cell differentiation(GO:0035881)
0.2 1.8 GO:0071420 cellular response to histamine(GO:0071420)
0.2 1.1 GO:0090272 negative regulation of fibroblast growth factor production(GO:0090272)
0.2 0.7 GO:0046898 response to cycloheximide(GO:0046898)
0.2 1.0 GO:0000733 DNA strand renaturation(GO:0000733)
0.1 0.9 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.4 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.1 0.8 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.5 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.6 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 0.6 GO:0007603 phototransduction, visible light(GO:0007603)
0.1 1.4 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.1 0.6 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 1.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 1.1 GO:0006824 cobalt ion transport(GO:0006824)
0.1 0.6 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.1 0.7 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 6.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 0.3 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.1 0.3 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 0.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 1.0 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.1 0.5 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.0 0.5 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.9 GO:0014823 response to activity(GO:0014823)
0.0 0.6 GO:0007202 activation of phospholipase C activity(GO:0007202) positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.2 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.5 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.7 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 0.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.1 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.3 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.2 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0 0.5 GO:0010566 regulation of ketone biosynthetic process(GO:0010566)
0.0 4.9 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation(GO:0050731)
0.0 0.9 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.2 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 2.5 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.2 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 0.2 GO:0032782 bile acid secretion(GO:0032782)
0.0 3.3 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 1.2 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.5 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.9 GO:0042551 neuron maturation(GO:0042551)
0.0 0.1 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.2 GO:0042407 cristae formation(GO:0042407)
0.0 0.7 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.8 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.4 GO:1903146 regulation of mitophagy(GO:1903146)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.2 3.4 GO:0031045 dense core granule(GO:0031045)
0.2 1.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 1.8 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 0.8 GO:0001739 sex chromatin(GO:0001739)
0.1 0.5 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 1.1 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 0.7 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 1.0 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.1 1.1 GO:0097470 ribbon synapse(GO:0097470)
0.1 2.1 GO:0032590 dendrite membrane(GO:0032590)
0.1 0.5 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.3 GO:0001652 granular component(GO:0001652)
0.1 0.7 GO:0043231 intracellular membrane-bounded organelle(GO:0043231)
0.1 0.6 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 6.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.7 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.8 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.4 GO:0031143 pseudopodium(GO:0031143)
0.0 0.4 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.9 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 2.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.7 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.7 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.3 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.3 GO:0030914 STAGA complex(GO:0030914)
0.0 1.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.9 GO:0005844 polysome(GO:0005844)
0.0 0.6 GO:0016235 aggresome(GO:0016235)
0.0 0.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2 0.9 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2 0.7 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.2 1.0 GO:0009378 four-way junction helicase activity(GO:0009378)
0.2 3.4 GO:0042056 chemoattractant activity(GO:0042056)
0.1 1.1 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 1.1 GO:0015087 cobalt ion transmembrane transporter activity(GO:0015087)
0.1 0.3 GO:0008988 rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) U6 snRNA 3'-end binding(GO:0030629)
0.1 0.8 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 2.1 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.1 0.6 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 1.8 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 0.9 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 0.8 GO:0005523 tropomyosin binding(GO:0005523)
0.1 1.0 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.5 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.7 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.9 GO:0001618 virus receptor activity(GO:0001618)
0.1 3.3 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.6 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1 1.1 GO:0001848 complement binding(GO:0001848)
0.0 0.2 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.3 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 1.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.7 GO:0031489 myosin V binding(GO:0031489)
0.0 0.5 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.5 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.6 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.6 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.1 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.0 0.6 GO:0050699 WW domain binding(GO:0050699)
0.0 1.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 6.9 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.4 GO:0042974 retinoic acid receptor binding(GO:0042974)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.1 4.4 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
0.1 4.9 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 0.6 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 3.3 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.0 0.9 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 0.7 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.3 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.0 0.3 PID_MYC_PATHWAY C-MYC pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.5 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.1 0.8 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.1 1.8 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.1 4.9 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.2 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 0.4 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 0.7 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 0.9 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.7 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.0 1.0 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.9 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.4 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.5 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.5 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.2 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.4 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 1.8 REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS Genes involved in G alpha (q) signalling events