Motif ID: Zic2

Z-value: 0.592


Transcription factors associated with Zic2:

Gene SymbolEntrez IDGene Name
Zic2 ENSMUSG00000061524.8 Zic2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zic2mm10_v2_chr14_+_122475397_1224754350.202.2e-01Click!


Activity profile for motif Zic2.

activity profile for motif Zic2


Sorted Z-values histogram for motif Zic2

Sorted Z-values for motif Zic2



Network of associatons between targets according to the STRING database.



First level regulatory network of Zic2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_12026732 1.367 ENSMUST00000143915.1
Grb10
growth factor receptor bound protein 10
chr11_-_12026237 1.365 ENSMUST00000150972.1
Grb10
growth factor receptor bound protein 10
chr5_+_140607334 1.206 ENSMUST00000031555.1
Lfng
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr4_-_143299498 1.194 ENSMUST00000030317.7
Pdpn
podoplanin
chr3_-_153725062 1.059 ENSMUST00000064460.5
St6galnac3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr15_-_8710409 1.056 ENSMUST00000157065.1
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr7_+_117380937 1.045 ENSMUST00000032892.5
Xylt1
xylosyltransferase 1
chr4_-_143299463 1.001 ENSMUST00000119654.1
Pdpn
podoplanin
chr11_+_105292637 0.966 ENSMUST00000100335.3
ENSMUST00000021038.4
Mrc2

mannose receptor, C type 2

chr9_+_104002546 0.935 ENSMUST00000035167.8
ENSMUST00000117054.1
Nphp3

nephronophthisis 3 (adolescent)

chr11_+_63128973 0.927 ENSMUST00000108702.1
Pmp22
peripheral myelin protein 22
chr15_+_25773985 0.921 ENSMUST00000125667.1
Myo10
myosin X
chr8_+_94179089 0.860 ENSMUST00000034215.6
Mt1
metallothionein 1
chr11_-_102946688 0.859 ENSMUST00000057849.5
C1ql1
complement component 1, q subcomponent-like 1
chr8_-_105471481 0.859 ENSMUST00000014990.6
Tppp3
tubulin polymerization-promoting protein family member 3
chr1_+_74661794 0.801 ENSMUST00000129890.1
Ttll4
tubulin tyrosine ligase-like family, member 4
chr8_+_12395287 0.789 ENSMUST00000180353.1
Sox1
SRY-box containing gene 1
chr7_-_19699008 0.782 ENSMUST00000174355.1
ENSMUST00000172983.1
ENSMUST00000174710.1
ENSMUST00000167646.2
ENSMUST00000003066.9
ENSMUST00000174064.1
Apoe





apolipoprotein E





chr4_-_41503046 0.771 ENSMUST00000054920.4
AI464131
expressed sequence AI464131
chr10_-_42583628 0.747 ENSMUST00000019938.4
Nr2e1
nuclear receptor subfamily 2, group E, member 1
chr11_-_68386974 0.742 ENSMUST00000135141.1
Ntn1
netrin 1
chr2_-_93452679 0.718 ENSMUST00000111257.1
ENSMUST00000145553.1
Cd82

CD82 antigen

chr11_-_79146407 0.717 ENSMUST00000018478.4
ENSMUST00000108264.1
Ksr1

kinase suppressor of ras 1

chr14_+_27039001 0.715 ENSMUST00000035336.3
Il17rd
interleukin 17 receptor D
chr5_-_148392810 0.709 ENSMUST00000138257.1
Slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr7_-_142899985 0.705 ENSMUST00000000219.3
Th
tyrosine hydroxylase
chr9_-_60522017 0.679 ENSMUST00000140824.1
Thsd4
thrombospondin, type I, domain containing 4
chr13_+_58806564 0.676 ENSMUST00000109838.2
Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chr5_+_105519388 0.661 ENSMUST00000067924.6
ENSMUST00000150981.1
Lrrc8c

leucine rich repeat containing 8 family, member C

chr14_-_122465677 0.659 ENSMUST00000039118.6
Zic5
zinc finger protein of the cerebellum 5
chr14_+_55853997 0.653 ENSMUST00000100529.3
Nynrin
NYN domain and retroviral integrase containing
chr4_+_136172367 0.649 ENSMUST00000061721.5
E2f2
E2F transcription factor 2
chr10_-_18743691 0.638 ENSMUST00000019999.5
D10Bwg1379e
DNA segment, Chr 10, Brigham & Women's Genetics 1379 expressed
chr5_-_142895233 0.625 ENSMUST00000035985.7
Fbxl18
F-box and leucine-rich repeat protein 18
chr7_-_44997535 0.613 ENSMUST00000124232.1
ENSMUST00000003290.4
Bcl2l12

BCL2-like 12 (proline rich)

chr14_-_78725089 0.607 ENSMUST00000074729.5
Dgkh
diacylglycerol kinase, eta
chr4_+_137913471 0.597 ENSMUST00000151110.1
Ece1
endothelin converting enzyme 1
chr17_+_86963279 0.594 ENSMUST00000139344.1
Rhoq
ras homolog gene family, member Q
chr18_-_24709348 0.584 ENSMUST00000067987.1
Gm9955
predicted gene 9955
chr2_+_31572775 0.567 ENSMUST00000137889.1
Fubp3
far upstream element (FUSE) binding protein 3
chr12_-_80260091 0.564 ENSMUST00000167327.1
Actn1
actinin, alpha 1
chr9_-_60838200 0.554 ENSMUST00000063858.7
Gm9869
predicted gene 9869
chrX_-_36991724 0.553 ENSMUST00000152291.1
Sept6
septin 6
chr7_-_16476765 0.553 ENSMUST00000002053.8
Npas1
neuronal PAS domain protein 1
chr12_+_81026800 0.550 ENSMUST00000110347.2
ENSMUST00000021564.4
ENSMUST00000129362.1
Smoc1


SPARC related modular calcium binding 1


chr14_-_26170283 0.547 ENSMUST00000100809.4
Plac9b
placenta specific 9b
chr19_-_4439388 0.541 ENSMUST00000117462.1
ENSMUST00000048197.3
Rhod

ras homolog gene family, member D

chr14_-_57664954 0.532 ENSMUST00000089482.5
Xpo4
exportin 4
chr2_-_75704535 0.528 ENSMUST00000102672.4
Nfe2l2
nuclear factor, erythroid derived 2, like 2
chr4_+_42240639 0.524 ENSMUST00000117202.2
Gm10600
predicted gene 10600
chr10_+_67979569 0.516 ENSMUST00000118160.1
Rtkn2
rhotekin 2
chr1_+_153665587 0.516 ENSMUST00000147700.1
Rgs8
regulator of G-protein signaling 8
chr7_-_19698206 0.508 ENSMUST00000172808.1
ENSMUST00000174191.1
Apoe

apolipoprotein E

chr5_+_108694222 0.505 ENSMUST00000013633.8
ENSMUST00000112560.3
Fgfrl1

fibroblast growth factor receptor-like 1

chr10_-_77113676 0.501 ENSMUST00000072755.4
ENSMUST00000105409.1
Col18a1

collagen, type XVIII, alpha 1

chr18_+_82910863 0.496 ENSMUST00000171238.1
Zfp516
zinc finger protein 516
chr6_-_31563978 0.495 ENSMUST00000026698.7
Podxl
podocalyxin-like
chr10_+_62071014 0.492 ENSMUST00000053865.5
Gm5424
predicted gene 5424
chr10_+_67979592 0.492 ENSMUST00000105437.1
Rtkn2
rhotekin 2
chr2_+_92915080 0.484 ENSMUST00000028648.2
Syt13
synaptotagmin XIII
chr1_-_170589791 0.483 ENSMUST00000161966.1
ENSMUST00000160456.1
Nos1ap

nitric oxide synthase 1 (neuronal) adaptor protein

chr14_-_31206666 0.478 ENSMUST00000165981.1
ENSMUST00000171735.1
Nisch

nischarin

chr12_-_56536895 0.474 ENSMUST00000001536.8
Nkx2-1
NK2 homeobox 1
chr2_-_180225812 0.473 ENSMUST00000015791.5
Lama5
laminin, alpha 5
chr7_-_17056669 0.467 ENSMUST00000037762.4
Hif3a
hypoxia inducible factor 3, alpha subunit
chr10_+_67979709 0.463 ENSMUST00000117086.1
Rtkn2
rhotekin 2
chr10_-_61452658 0.463 ENSMUST00000167087.1
ENSMUST00000020288.7
Eif4ebp2

eukaryotic translation initiation factor 4E binding protein 2

chr9_+_49518336 0.462 ENSMUST00000068730.3
Gm11149
predicted gene 11149
chr14_-_34374617 0.453 ENSMUST00000023826.4
Sncg
synuclein, gamma
chr4_+_42091207 0.452 ENSMUST00000178882.1
Gm3893
predicted gene 3893
chr9_+_107576915 0.449 ENSMUST00000112387.2
ENSMUST00000123005.1
ENSMUST00000010195.7
ENSMUST00000144392.1
Hyal1



hyaluronoglucosaminidase 1



chr2_+_31950257 0.447 ENSMUST00000001920.7
Aif1l
allograft inflammatory factor 1-like
chr11_-_106487833 0.432 ENSMUST00000106801.1
Ern1
endoplasmic reticulum (ER) to nucleus signalling 1
chr5_-_21701332 0.427 ENSMUST00000115217.1
ENSMUST00000060899.8
Napepld

N-acyl phosphatidylethanolamine phospholipase D

chr11_-_119355484 0.427 ENSMUST00000100172.2
ENSMUST00000005173.4
Sgsh

N-sulfoglucosamine sulfohydrolase (sulfamidase)

chr12_-_104865076 0.427 ENSMUST00000109937.1
ENSMUST00000109936.1
Clmn

calmin

chr8_+_45628176 0.426 ENSMUST00000130850.1
Sorbs2
sorbin and SH3 domain containing 2
chr4_+_126556994 0.415 ENSMUST00000147675.1
Clspn
claspin
chr2_+_106695594 0.407 ENSMUST00000016530.7
Mpped2
metallophosphoesterase domain containing 2
chr5_+_92603039 0.405 ENSMUST00000050952.3
Stbd1
starch binding domain 1
chr2_+_150786735 0.405 ENSMUST00000045441.7
Pygb
brain glycogen phosphorylase
chr8_-_31918203 0.405 ENSMUST00000073884.4
Nrg1
neuregulin 1
chr14_+_55854115 0.392 ENSMUST00000168479.1
Nynrin
NYN domain and retroviral integrase containing
chr7_+_79660196 0.389 ENSMUST00000035977.7
Ticrr
TOPBP1-interacting checkpoint and replication regulator
chr6_+_65671590 0.388 ENSMUST00000054351.4
Ndnf
neuron-derived neurotrophic factor
chr4_-_58987095 0.386 ENSMUST00000030069.6
Ptgr1
prostaglandin reductase 1
chr5_-_122002340 0.386 ENSMUST00000134326.1
Cux2
cut-like homeobox 2
chr1_+_74661714 0.384 ENSMUST00000042125.8
ENSMUST00000141119.1
Ttll4

tubulin tyrosine ligase-like family, member 4

chr3_+_154597352 0.383 ENSMUST00000140644.1
ENSMUST00000144764.1
ENSMUST00000155232.1
Cryz


crystallin, zeta


chr7_-_44997221 0.382 ENSMUST00000152341.1
Bcl2l12
BCL2-like 12 (proline rich)
chr7_+_25221417 0.382 ENSMUST00000055604.4
Zfp526
zinc finger protein 526
chr8_+_40423786 0.376 ENSMUST00000049389.4
ENSMUST00000128166.1
ENSMUST00000167766.1
Zdhhc2


zinc finger, DHHC domain containing 2


chrX_+_151521146 0.374 ENSMUST00000112670.1
ENSMUST00000046962.4
ENSMUST00000112668.2
ENSMUST00000046950.6
Phf8



PHD finger protein 8



chr5_+_92683625 0.370 ENSMUST00000168878.1
Shroom3
shroom family member 3
chr8_-_104395765 0.368 ENSMUST00000179802.1
Cmtm4
CKLF-like MARVEL transmembrane domain containing 4
chr5_+_92897981 0.364 ENSMUST00000113051.2
Shroom3
shroom family member 3
chr1_-_153332724 0.363 ENSMUST00000027752.8
Lamc1
laminin, gamma 1
chr5_-_92278155 0.362 ENSMUST00000159345.1
ENSMUST00000113102.3
Naaa

N-acylethanolamine acid amidase

chr1_-_36547194 0.361 ENSMUST00000001172.5
Ankrd39
ankyrin repeat domain 39
chrX_+_170009659 0.361 ENSMUST00000179760.1
Gm21887
predicted gene, 21887
chr7_+_34251038 0.358 ENSMUST00000105172.1
Gm6096
predicted gene 6096
chr15_-_76069681 0.355 ENSMUST00000002603.5
ENSMUST00000063747.5
Scrib

scribbled homolog (Drosophila)

chr10_-_13474361 0.353 ENSMUST00000105547.1
Phactr2
phosphatase and actin regulator 2
chr13_+_44731281 0.352 ENSMUST00000174086.1
Jarid2
jumonji, AT rich interactive domain 2
chr8_+_71406003 0.347 ENSMUST00000119976.1
ENSMUST00000120725.1
Ankle1

ankyrin repeat and LEM domain containing 1

chr15_-_50889043 0.346 ENSMUST00000183997.1
ENSMUST00000183757.1
Trps1

trichorhinophalangeal syndrome I (human)

chr16_-_10313940 0.344 ENSMUST00000078357.4
Emp2
epithelial membrane protein 2
chr4_-_96591555 0.343 ENSMUST00000055693.8
Cyp2j9
cytochrome P450, family 2, subfamily j, polypeptide 9
chrX_-_143933089 0.342 ENSMUST00000087313.3
Dcx
doublecortin
chrX_+_151520655 0.341 ENSMUST00000112666.1
ENSMUST00000168501.1
ENSMUST00000112662.2
Phf8


PHD finger protein 8


chr17_+_24352037 0.338 ENSMUST00000079594.5
Abca3
ATP-binding cassette, sub-family A (ABC1), member 3
chr1_+_153665627 0.337 ENSMUST00000147482.1
Rgs8
regulator of G-protein signaling 8
chr2_-_33468493 0.334 ENSMUST00000113156.1
ENSMUST00000028125.5
ENSMUST00000126442.1
Zbtb43


zinc finger and BTB domain containing 43


chr5_-_137116177 0.334 ENSMUST00000054384.5
ENSMUST00000152207.1
Trim56

tripartite motif-containing 56

chr4_+_98546919 0.329 ENSMUST00000030290.7
Inadl
InaD-like (Drosophila)
chr14_+_19751257 0.325 ENSMUST00000022340.3
Nid2
nidogen 2
chr11_-_90638062 0.319 ENSMUST00000020858.7
ENSMUST00000107875.1
ENSMUST00000107872.1
ENSMUST00000143203.1
Stxbp4



syntaxin binding protein 4



chr18_+_31609512 0.316 ENSMUST00000164667.1
B930094E09Rik
RIKEN cDNA B930094E09 gene
chr9_+_107400043 0.314 ENSMUST00000166799.1
ENSMUST00000170737.1
Cacna2d2

calcium channel, voltage-dependent, alpha 2/delta subunit 2

chr16_+_4639941 0.314 ENSMUST00000038770.3
Vasn
vasorin
chr19_-_55099417 0.314 ENSMUST00000061856.5
Gpam
glycerol-3-phosphate acyltransferase, mitochondrial
chr5_+_139423151 0.313 ENSMUST00000066211.4
Gper1
G protein-coupled estrogen receptor 1
chr5_+_135670027 0.312 ENSMUST00000153500.1
Por
P450 (cytochrome) oxidoreductase
chr5_+_105732063 0.310 ENSMUST00000154807.1
Lrrc8d
leucine rich repeat containing 8D
chr1_-_36244245 0.306 ENSMUST00000046875.7
Uggt1
UDP-glucose glycoprotein glucosyltransferase 1
chr8_+_45627946 0.305 ENSMUST00000145458.1
Sorbs2
sorbin and SH3 domain containing 2
chrX_+_56317608 0.303 ENSMUST00000151426.1
ENSMUST00000138262.1
1600025M17Rik

RIKEN cDNA 1600025M17 gene

chr16_+_35983424 0.303 ENSMUST00000173555.1
Kpna1
karyopherin (importin) alpha 1
chr9_+_110344185 0.301 ENSMUST00000142100.1
Scap
SREBF chaperone
chr17_-_45572495 0.298 ENSMUST00000130406.1
Hsp90ab1
heat shock protein 90 alpha (cytosolic), class B member 1
chr5_+_105731755 0.291 ENSMUST00000127686.1
Lrrc8d
leucine rich repeat containing 8D
chr5_+_10236829 0.290 ENSMUST00000101606.3
Gm10482
predicted gene 10482
chr15_-_82244716 0.286 ENSMUST00000089155.4
ENSMUST00000089157.3
Cenpm

centromere protein M

chr2_-_93996354 0.285 ENSMUST00000183110.1
Gm27027
predicted gene, 27027
chr2_-_38287174 0.275 ENSMUST00000130472.1
Dennd1a
DENN/MADD domain containing 1A
chr1_-_71103146 0.274 ENSMUST00000027393.7
Bard1
BRCA1 associated RING domain 1
chr8_+_46151749 0.272 ENSMUST00000154040.1
4933411K20Rik
RIKEN cDNA 4933411K20 gene
chr9_+_105642957 0.268 ENSMUST00000065778.6
Pik3r4
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 4, p150
chr2_+_170731807 0.268 ENSMUST00000029075.4
Dok5
docking protein 5
chr1_+_153665666 0.266 ENSMUST00000111814.1
ENSMUST00000111810.1
Rgs8

regulator of G-protein signaling 8

chr7_+_27692502 0.263 ENSMUST00000076421.6
C030039L03Rik
RIKEN cDNA C030039L03 gene
chr11_+_53770014 0.263 ENSMUST00000108920.2
ENSMUST00000140866.1
ENSMUST00000108922.1
Irf1


interferon regulatory factor 1


chr11_-_101171302 0.262 ENSMUST00000164474.1
ENSMUST00000043397.7
Plekhh3

pleckstrin homology domain containing, family H (with MyTH4 domain) member 3

chr1_-_128359610 0.262 ENSMUST00000027601.4
Mcm6
minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)
chr4_-_116144609 0.262 ENSMUST00000030469.4
Lurap1
leucine rich adaptor protein 1
chr17_-_27022786 0.262 ENSMUST00000143158.1
Bak1
BCL2-antagonist/killer 1
chr8_-_121652895 0.258 ENSMUST00000046386.4
Zcchc14
zinc finger, CCHC domain containing 14
chr11_+_43528759 0.257 ENSMUST00000050574.6
Ccnjl
cyclin J-like
chr5_+_110839973 0.256 ENSMUST00000066160.1
Chek2
checkpoint kinase 2
chr11_+_94327984 0.256 ENSMUST00000107818.2
ENSMUST00000051221.6
Ankrd40

ankyrin repeat domain 40

chr8_+_92827273 0.255 ENSMUST00000034187.7
Mmp2
matrix metallopeptidase 2
chr8_+_31187317 0.254 ENSMUST00000066173.5
ENSMUST00000161788.1
ENSMUST00000110527.2
ENSMUST00000161502.1
Fut10



fucosyltransferase 10



chr15_+_98708187 0.253 ENSMUST00000003444.4
Ccdc65
coiled-coil domain containing 65
chr14_-_67933512 0.252 ENSMUST00000039135.4
Dock5
dedicator of cytokinesis 5
chr8_+_110079758 0.249 ENSMUST00000058804.8
Zfp612
zinc finger protein 612
chr18_+_65698253 0.245 ENSMUST00000115097.1
ENSMUST00000117694.1
Oacyl

O-acyltransferase like

chr15_+_85205949 0.244 ENSMUST00000057410.7
ENSMUST00000109432.3
Fbln1

fibulin 1

chr5_+_43662373 0.244 ENSMUST00000048150.8
Cc2d2a
coiled-coil and C2 domain containing 2A
chr7_+_35119285 0.243 ENSMUST00000042985.9
Cebpa
CCAAT/enhancer binding protein (C/EBP), alpha
chr11_-_71004387 0.243 ENSMUST00000124464.1
ENSMUST00000108527.1
Dhx33

DEAH (Asp-Glu-Ala-His) box polypeptide 33

chr3_+_135485605 0.240 ENSMUST00000029814.9
Manba
mannosidase, beta A, lysosomal
chr4_+_148041172 0.239 ENSMUST00000069604.8
Mthfr
5,10-methylenetetrahydrofolate reductase
chr17_-_25727364 0.239 ENSMUST00000170070.1
ENSMUST00000048054.7
Chtf18

CTF18, chromosome transmission fidelity factor 18

chr17_+_4994904 0.239 ENSMUST00000092723.4
ENSMUST00000115797.2
Arid1b

AT rich interactive domain 1B (SWI-like)

chr10_-_107123585 0.238 ENSMUST00000165067.1
ENSMUST00000044668.4
Acss3

acyl-CoA synthetase short-chain family member 3

chr1_+_9547948 0.234 ENSMUST00000144177.1
Adhfe1
alcohol dehydrogenase, iron containing, 1
chr17_+_47737030 0.233 ENSMUST00000086932.3
Tfeb
transcription factor EB
chr5_-_67847360 0.233 ENSMUST00000072971.6
Atp8a1
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
chr8_+_95320440 0.231 ENSMUST00000162294.1
Tepp
testis, prostate and placenta expressed
chr9_+_88839164 0.231 ENSMUST00000163255.2
Trim43c
tripartite motif-containing 43C
chr17_+_24352017 0.229 ENSMUST00000039013.8
Abca3
ATP-binding cassette, sub-family A (ABC1), member 3
chr14_-_64455903 0.228 ENSMUST00000067927.7
Msra
methionine sulfoxide reductase A
chr10_+_18845071 0.228 ENSMUST00000019998.7
Perp
PERP, TP53 apoptosis effector
chr16_+_32431225 0.227 ENSMUST00000115140.1
Pcyt1a
phosphate cytidylyltransferase 1, choline, alpha isoform
chr17_+_32685610 0.227 ENSMUST00000168171.1
Cyp4f15
cytochrome P450, family 4, subfamily f, polypeptide 15
chr6_-_72617000 0.226 ENSMUST00000070524.4
Tgoln1
trans-golgi network protein
chr11_+_99041237 0.225 ENSMUST00000017637.6
Igfbp4
insulin-like growth factor binding protein 4
chrX_-_74085656 0.222 ENSMUST00000033770.6
Mecp2
methyl CpG binding protein 2
chr19_-_10101501 0.221 ENSMUST00000025567.7
Fads2
fatty acid desaturase 2
chr7_+_45434876 0.219 ENSMUST00000107766.1
Gys1
glycogen synthase 1, muscle
chr13_+_34037619 0.218 ENSMUST00000040656.6
Bphl
biphenyl hydrolase-like (serine hydrolase, breast epithelial mucin-associated antigen)
chr5_+_93093428 0.217 ENSMUST00000074733.7
Sept11
septin 11
chr1_+_153665274 0.217 ENSMUST00000152114.1
ENSMUST00000111812.1
Rgs8

regulator of G-protein signaling 8

chr6_+_48554776 0.216 ENSMUST00000114545.1
ENSMUST00000153222.1
ENSMUST00000101436.2
Lrrc61


leucine rich repeat containing 61


chr7_-_44816586 0.215 ENSMUST00000047356.8
Atf5
activating transcription factor 5
chr5_-_24351604 0.214 ENSMUST00000036092.7
Kcnh2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr2_-_25469742 0.213 ENSMUST00000114259.2
ENSMUST00000015234.6
Ptgds

prostaglandin D2 synthase (brain)

chr9_+_91378636 0.211 ENSMUST00000066384.5
Zic4
zinc finger protein of the cerebellum 4
chr10_+_70175011 0.210 ENSMUST00000156001.1
ENSMUST00000135607.1
Ccdc6

coiled-coil domain containing 6

chr8_-_8639363 0.210 ENSMUST00000152698.1
Efnb2
ephrin B2
chr10_+_84622365 0.210 ENSMUST00000077175.5
Polr3b
polymerase (RNA) III (DNA directed) polypeptide B
chr8_+_13287887 0.209 ENSMUST00000045229.5
Tmco3
transmembrane and coiled-coil domains 3
chr8_+_124023394 0.209 ENSMUST00000034457.8
Urb2
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr6_+_91684061 0.209 ENSMUST00000032185.7
Slc6a6
solute carrier family 6 (neurotransmitter transporter, taurine), member 6
chr4_-_149909719 0.205 ENSMUST00000105685.1
Spsb1
splA/ryanodine receptor domain and SOCS box containing 1
chr14_+_51091077 0.202 ENSMUST00000022428.5
ENSMUST00000171688.1
Rnase4
Ang
ribonuclease, RNase A family 4
angiogenin, ribonuclease, RNase A family, 5
chr19_+_40831296 0.201 ENSMUST00000119316.1
Ccnj
cyclin J
chrX_+_71364901 0.200 ENSMUST00000132837.1
Mtmr1
myotubularin related protein 1
chr5_+_124194894 0.199 ENSMUST00000159053.1
ENSMUST00000162577.1
Gm16338

predicted gene 16338

chr11_-_6475992 0.199 ENSMUST00000179343.1
Purb
purine rich element binding protein B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:1903002 regulation of lipid transport across blood brain barrier(GO:1903000) positive regulation of lipid transport across blood brain barrier(GO:1903002)
0.4 2.2 GO:1901731 positive regulation of platelet aggregation(GO:1901731)
0.3 0.9 GO:0048496 maintenance of organ identity(GO:0048496)
0.3 2.7 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.3 1.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.2 1.2 GO:0007386 compartment pattern specification(GO:0007386)
0.2 0.7 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.2 0.9 GO:0061743 motor learning(GO:0061743)
0.2 0.6 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.2 0.7 GO:0042414 epinephrine metabolic process(GO:0042414)
0.2 0.9 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.2 0.5 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.2 0.5 GO:0021759 globus pallidus development(GO:0021759)
0.1 0.4 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.1 0.7 GO:0021764 amygdala development(GO:0021764)
0.1 0.4 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.1 0.4 GO:1904809 dense core granule localization(GO:0032253) cellular response to isoquinoline alkaloid(GO:0071317) dense core granule transport(GO:1901950) regulation of dense core granule transport(GO:1904809) positive regulation of dense core granule transport(GO:1904811)
0.1 0.5 GO:1902037 proteasomal ubiquitin-independent protein catabolic process(GO:0010499) positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091) negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.1 0.3 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.1 1.0 GO:0015074 DNA integration(GO:0015074)
0.1 0.2 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.1 0.4 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.1 1.1 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.3 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.1 0.7 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.1 1.0 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1 1.0 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.3 GO:0097278 transforming growth factor beta activation(GO:0036363) complement-dependent cytotoxicity(GO:0097278)
0.1 1.5 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 0.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.9 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.1 0.6 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.1 0.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.3 GO:0010248 B cell negative selection(GO:0002352) establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.1 0.3 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.1 0.4 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.1 0.4 GO:1903998 regulation of eating behavior(GO:1903998)
0.1 0.7 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.1 0.2 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931) transforming growth factor-beta secretion(GO:0038044) blood coagulation, fibrin clot formation(GO:0072378)
0.1 1.4 GO:0030574 collagen catabolic process(GO:0030574)
0.1 0.2 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.1 0.3 GO:1904706 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579) negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.1 0.4 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 0.3 GO:0046210 nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.1 0.2 GO:0009814 defense response, incompatible interaction(GO:0009814)
0.1 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.3 GO:0030576 Cajal body organization(GO:0030576)
0.1 0.5 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 0.2 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 1.4 GO:0032060 bleb assembly(GO:0032060)
0.1 0.8 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.1 1.0 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.1 0.3 GO:1903463 regulation of mitotic cell cycle DNA replication(GO:1903463)
0.1 0.3 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 0.3 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.1 0.3 GO:0055091 phospholipid homeostasis(GO:0055091)
0.1 0.2 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.1 0.2 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 0.2 GO:0006601 creatine biosynthetic process(GO:0006601)
0.1 0.2 GO:0070829 heterochromatin maintenance(GO:0070829)
0.1 0.4 GO:0021830 interneuron migration from the subpallium to the cortex(GO:0021830)
0.1 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.2 GO:0002934 desmosome organization(GO:0002934)
0.1 0.3 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 0.8 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.5 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.7 GO:0015809 arginine transport(GO:0015809)
0.0 0.1 GO:0002554 serotonin secretion by platelet(GO:0002554) interleukin-3 production(GO:0032632) beta selection(GO:0043366)
0.0 0.3 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.0 0.5 GO:0060539 diaphragm development(GO:0060539)
0.0 0.3 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.3 GO:0051775 response to redox state(GO:0051775)
0.0 0.9 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 1.1 GO:0006677 glycosylceramide metabolic process(GO:0006677)
0.0 0.8 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.2 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.2 GO:0000050 urea cycle(GO:0000050) urea metabolic process(GO:0019627)
0.0 0.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:2000224 regulation of testosterone biosynthetic process(GO:2000224)
0.0 0.2 GO:0006868 glutamine transport(GO:0006868)
0.0 0.1 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
0.0 0.2 GO:1902302 regulation of potassium ion export(GO:1902302)
0.0 0.1 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.2 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.0 0.1 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.2 GO:0040031 snRNA modification(GO:0040031)
0.0 0.5 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.6 GO:0042711 maternal behavior(GO:0042711)
0.0 0.5 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.1 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.0 0.2 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.2 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.0 GO:0015822 ornithine transport(GO:0015822)
0.0 0.1 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 0.1 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 1.3 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.2 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.1 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.7 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.3 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.1 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.0 0.2 GO:0003062 regulation of heart rate by chemical signal(GO:0003062)
0.0 0.2 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.0 0.6 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 0.8 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.3 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.0 0.0 GO:0002901 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.0 0.2 GO:0035459 cargo loading into vesicle(GO:0035459) cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0048563 post-embryonic organ morphogenesis(GO:0048563)
0.0 0.1 GO:2000409 positive regulation of T cell extravasation(GO:2000409)
0.0 0.1 GO:0046959 habituation(GO:0046959)
0.0 0.3 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.5 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.6 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.5 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.5 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 0.2 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.2 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.5 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.9 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.2 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.3 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 0.3 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.5 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.1 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.3 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.0 0.1 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.2 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.1 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.1 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 0.4 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.2 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.2 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.1 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.1 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0 0.1 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.0 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.0 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.2 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.1 GO:0006265 DNA topological change(GO:0006265)
0.0 0.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.1 GO:0035336 long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.0 0.1 GO:0035188 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.2 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.0 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.0 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.0 0.8 GO:0046785 microtubule polymerization(GO:0046785)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012) negative regulation of nonmotile primary cilium assembly(GO:1902856)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.3 0.9 GO:0097543 ciliary inversin compartment(GO:0097543)
0.2 2.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 0.7 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.2 0.6 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.2 0.8 GO:0032127 dense core granule membrane(GO:0032127)
0.2 0.6 GO:0005940 septin ring(GO:0005940)
0.2 0.7 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.2 0.9 GO:0044301 climbing fiber(GO:0044301)
0.1 0.4 GO:1990597 AIP1-IRE1 complex(GO:1990597)
0.1 0.6 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 1.0 GO:0097427 microtubule bundle(GO:0097427)
0.1 0.3 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 0.2 GO:0071953 fibrinogen complex(GO:0005577) elastic fiber(GO:0071953)
0.1 0.2 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.1 0.2 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.2 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 0.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.7 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.2 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.3 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.4 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.1 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.9 GO:0043218 compact myelin(GO:0043218)
0.0 1.3 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.5 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.5 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 1.3 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.2 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.3 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.2 GO:0036038 MKS complex(GO:0036038)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.2 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.3 GO:0030673 axolemma(GO:0030673)
0.0 0.7 GO:0016459 myosin complex(GO:0016459)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0032421 stereocilium(GO:0032420) stereocilium bundle(GO:0032421)
0.0 2.9 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.3 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0046911 hydroxyapatite binding(GO:0046848) metal chelating activity(GO:0046911) phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.4 1.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.3 1.0 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.2 0.7 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.2 0.7 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.2 2.2 GO:0015250 water channel activity(GO:0015250)
0.2 1.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.2 1.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.4 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.7 GO:0035240 dopamine binding(GO:0035240)
0.1 0.7 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 1.1 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.1 0.4 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.1 0.4 GO:2001069 glycogen binding(GO:2001069)
0.1 0.6 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 0.4 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.1 0.4 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.1 1.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.3 GO:0070140 isopeptidase activity(GO:0070122) ubiquitin-like protein-specific isopeptidase activity(GO:0070138) SUMO-specific isopeptidase activity(GO:0070140)
0.1 0.4 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 0.7 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 0.2 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 0.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 0.4 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.1 0.2 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 0.3 GO:0016708 nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726)
0.1 2.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 0.6 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 0.3 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 0.1 GO:0001729 ceramide kinase activity(GO:0001729)
0.1 0.1 GO:0004645 phosphorylase activity(GO:0004645)
0.1 0.7 GO:0005522 profilin binding(GO:0005522)
0.1 0.5 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.3 GO:0030284 estrogen receptor activity(GO:0030284)
0.1 0.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.4 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.5 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.3 GO:0002135 CTP binding(GO:0002135)
0.0 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.2 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.2 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768)
0.0 0.2 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0 0.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.7 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.5 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 0.2 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.1 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.1 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 1.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.6 GO:0017166 vinculin binding(GO:0017166)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.3 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.2 GO:0004043 L-aminoadipate-semialdehyde dehydrogenase activity(GO:0004043)
0.0 0.1 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.4 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.1 GO:0004686 elongation factor-2 kinase activity(GO:0004686)
0.0 0.1 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.5 GO:0070402 NADPH binding(GO:0070402)
0.0 0.4 GO:0015923 mannosidase activity(GO:0015923)
0.0 0.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.0 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.4 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.2 GO:0000182 rDNA binding(GO:0000182)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.1 GO:0009881 photoreceptor activity(GO:0009881)
0.0 0.3 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.2 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 0.5 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.2 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0016004 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.9 GO:0030507 spectrin binding(GO:0030507)
0.0 0.2 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013)
0.0 0.7 GO:0005507 copper ion binding(GO:0005507)
0.0 0.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.5 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 1.0 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0035877 death effector domain binding(GO:0035877)
0.0 0.1 GO:2001070 starch binding(GO:2001070)
0.0 0.2 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 1.1 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.0 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0005212 structural constituent of eye lens(GO:0005212)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.6 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.5 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 1.1 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 0.7 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.4 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 0.8 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.0 0.8 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.5 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.3 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.0 0.5 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.7 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.8 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.0 0.8 PID_FGF_PATHWAY FGF signaling pathway
0.0 0.3 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.1 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.7 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 2.3 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.6 PID_ATR_PATHWAY ATR signaling pathway
0.0 0.2 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.0 0.3 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 0.1 PID_AVB3_OPN_PATHWAY Osteopontin-mediated events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.1 1.5 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.0 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 0.7 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.1 1.1 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 0.6 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 0.6 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.4 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.3 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 2.2 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.5 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.6 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.8 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.3 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.2 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.4 REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.4 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.0 0.4 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.9 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.6 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.3 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.0 0.4 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.2 REACTOME_ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.2 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.3 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.6 REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.0 0.2 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 0.2 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.3 REACTOME_INTEGRIN_ALPHAIIB_BETA3_SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.2 REACTOME_ABORTIVE_ELONGATION_OF_HIV1_TRANSCRIPT_IN_THE_ABSENCE_OF_TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 0.4 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases