Motif ID: Nkx6-1_Evx1_Hesx1

Z-value: 0.759

Transcription factors associated with Nkx6-1_Evx1_Hesx1:

Gene SymbolEntrez IDGene Name
Evx1 ENSMUSG00000005503.8 Evx1
Hesx1 ENSMUSG00000040726.8 Hesx1
Nkx6-1 ENSMUSG00000035187.8 Nkx6-1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nkx6-1mm10_v2_chr5_-_101665195_1016652260.296.8e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Nkx6-1_Evx1_Hesx1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_98053415 12.009 ENSMUST00000017544.2
Stac2
SH3 and cysteine rich domain 2
chr5_-_62766153 10.832 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr15_+_18818895 8.785 ENSMUST00000166873.2
Cdh10
cadherin 10
chr1_-_155417394 6.825 ENSMUST00000111775.1
ENSMUST00000111774.1
Xpr1

xenotropic and polytropic retrovirus receptor 1

chr3_-_49757257 6.568 ENSMUST00000035931.7
Pcdh18
protocadherin 18
chrX_-_143933089 5.073 ENSMUST00000087313.3
Dcx
doublecortin
chr18_+_23415400 4.962 ENSMUST00000115832.2
ENSMUST00000047954.7
Dtna

dystrobrevin alpha

chr6_-_101377897 4.821 ENSMUST00000075994.6
Pdzrn3
PDZ domain containing RING finger 3
chr13_+_94083490 4.629 ENSMUST00000156071.1
Lhfpl2
lipoma HMGIC fusion partner-like 2
chr16_-_97170707 4.103 ENSMUST00000056102.7
Dscam
Down syndrome cell adhesion molecule
chr8_-_34965631 3.948 ENSMUST00000033929.4
Tnks
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr9_+_113812547 3.625 ENSMUST00000166734.2
ENSMUST00000111838.2
ENSMUST00000163895.2
Clasp2


CLIP associating protein 2


chr4_+_108719649 3.548 ENSMUST00000178992.1
3110021N24Rik
RIKEN cDNA 3110021N24 gene
chr5_-_84417359 3.531 ENSMUST00000113401.1
Epha5
Eph receptor A5
chr1_-_24612700 3.374 ENSMUST00000088336.1
Gm10222
predicted gene 10222
chrM_+_9870 3.345 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr16_+_42907563 3.286 ENSMUST00000151244.1
ENSMUST00000114694.2
Zbtb20

zinc finger and BTB domain containing 20

chr9_-_55919605 3.273 ENSMUST00000037408.8
Scaper
S phase cyclin A-associated protein in the ER
chr4_-_155056784 3.271 ENSMUST00000131173.2
Plch2
phospholipase C, eta 2
chr9_-_96719404 3.174 ENSMUST00000140121.1
Zbtb38
zinc finger and BTB domain containing 38
chr3_+_62419668 3.147 ENSMUST00000161057.1
Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr17_+_3532554 3.021 ENSMUST00000168560.1
Cldn20
claudin 20
chr7_+_126950518 2.872 ENSMUST00000106335.1
ENSMUST00000146017.1
Sez6l2

seizure related 6 homolog like 2

chr5_-_62765618 2.861 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr13_+_42680565 2.840 ENSMUST00000128646.1
Phactr1
phosphatase and actin regulator 1
chr1_-_134955847 2.839 ENSMUST00000168381.1
Ppp1r12b
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr1_-_155417283 2.788 ENSMUST00000027741.5
Xpr1
xenotropic and polytropic retrovirus receptor 1
chr10_+_18469958 2.769 ENSMUST00000162891.1
ENSMUST00000100054.3
Nhsl1

NHS-like 1

chr13_+_44121167 2.696 ENSMUST00000163056.1
ENSMUST00000159595.1
Gm5083

predicted gene 5083

chr14_-_100149764 2.664 ENSMUST00000097079.4
Klf12
Kruppel-like factor 12
chrX_-_143933204 2.654 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chr1_+_72284367 2.618 ENSMUST00000027380.5
ENSMUST00000141783.1
Tmem169

transmembrane protein 169

chr2_+_69897255 2.583 ENSMUST00000131553.1
Ubr3
ubiquitin protein ligase E3 component n-recognin 3
chr2_-_79456750 2.539 ENSMUST00000041099.4
Neurod1
neurogenic differentiation 1
chr18_+_57468478 2.519 ENSMUST00000091892.2
Ctxn3
cortexin 3
chr9_-_96719549 2.491 ENSMUST00000128269.1
Zbtb38
zinc finger and BTB domain containing 38
chr7_+_126950687 2.474 ENSMUST00000106333.1
Sez6l2
seizure related 6 homolog like 2
chr11_+_75532099 2.442 ENSMUST00000169547.2
Slc43a2
solute carrier family 43, member 2
chr2_+_116067213 2.423 ENSMUST00000152412.1
G630016G05Rik
RIKEN cDNA G630016G05 gene
chr11_-_87359011 2.409 ENSMUST00000055438.4
Ppm1e
protein phosphatase 1E (PP2C domain containing)
chr7_+_126776939 2.375 ENSMUST00000038614.5
ENSMUST00000170882.1
ENSMUST00000106359.1
ENSMUST00000106357.1
ENSMUST00000145762.1
ENSMUST00000132643.1
ENSMUST00000106356.1
Ypel3






yippee-like 3 (Drosophila)






chr18_+_37518341 2.355 ENSMUST00000097609.1
Pcdhb22
protocadherin beta 22
chr5_+_19907774 2.308 ENSMUST00000115267.2
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chrM_+_10167 2.300 ENSMUST00000082414.1
mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr9_-_53975246 2.285 ENSMUST00000048409.7
Elmod1
ELMO/CED-12 domain containing 1
chr5_+_13398688 2.280 ENSMUST00000125629.1
Sema3a
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chrX_+_159708593 2.244 ENSMUST00000080394.6
Sh3kbp1
SH3-domain kinase binding protein 1
chr2_+_84734050 2.178 ENSMUST00000090729.2
Ypel4
yippee-like 4 (Drosophila)
chr17_+_3397189 2.173 ENSMUST00000072156.6
Tiam2
T cell lymphoma invasion and metastasis 2
chr7_+_29071597 2.166 ENSMUST00000180926.1
Gm26604
predicted gene, 26604
chr1_-_134955908 2.165 ENSMUST00000045665.6
ENSMUST00000086444.4
ENSMUST00000112163.1
Ppp1r12b


protein phosphatase 1, regulatory (inhibitor) subunit 12B


chr12_-_83487708 2.144 ENSMUST00000177959.1
ENSMUST00000178756.1
Dpf3

D4, zinc and double PHD fingers, family 3

chr10_+_127421208 2.129 ENSMUST00000168780.1
R3hdm2
R3H domain containing 2
chr6_-_136171722 2.116 ENSMUST00000053880.6
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr19_+_26749726 2.105 ENSMUST00000175842.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr9_+_32116040 2.080 ENSMUST00000174641.1
Arhgap32
Rho GTPase activating protein 32
chrX_+_159697308 2.060 ENSMUST00000123433.1
Sh3kbp1
SH3-domain kinase binding protein 1
chr3_-_80802789 2.054 ENSMUST00000107745.1
ENSMUST00000075316.4
Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr2_-_116067391 2.028 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr6_-_97459279 1.948 ENSMUST00000113359.1
Frmd4b
FERM domain containing 4B
chr11_+_23306910 1.936 ENSMUST00000137823.1
Usp34
ubiquitin specific peptidase 34
chr15_-_66812593 1.920 ENSMUST00000100572.3
Sla
src-like adaptor
chr10_+_39612934 1.912 ENSMUST00000019987.6
Traf3ip2
TRAF3 interacting protein 2
chr16_+_43247278 1.893 ENSMUST00000114691.1
ENSMUST00000079441.6
Zbtb20

zinc finger and BTB domain containing 20

chr1_-_132707304 1.863 ENSMUST00000043189.7
Nfasc
neurofascin
chr2_-_7395879 1.854 ENSMUST00000182404.1
Celf2
CUGBP, Elav-like family member 2
chrX_+_56454871 1.850 ENSMUST00000039374.2
ENSMUST00000101553.2
Ddx26b

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

chr8_+_4238815 1.820 ENSMUST00000003027.7
ENSMUST00000110999.1
Map2k7

mitogen-activated protein kinase kinase 7

chr6_+_29853746 1.804 ENSMUST00000064872.6
ENSMUST00000152581.1
ENSMUST00000176265.1
ENSMUST00000154079.1
Ahcyl2



S-adenosylhomocysteine hydrolase-like 2



chr2_-_5676046 1.787 ENSMUST00000114987.3
Camk1d
calcium/calmodulin-dependent protein kinase ID
chr16_-_37384915 1.742 ENSMUST00000114787.1
ENSMUST00000114782.1
ENSMUST00000023526.2
ENSMUST00000114775.1
Stxbp5l



syntaxin binding protein 5-like



chr15_+_55307743 1.730 ENSMUST00000023053.5
ENSMUST00000110221.2
ENSMUST00000110217.3
Col14a1


collagen, type XIV, alpha 1


chr19_-_4698668 1.721 ENSMUST00000177696.1
Gm960
predicted gene 960
chr16_-_45724600 1.694 ENSMUST00000096057.4
Tagln3
transgelin 3
chr13_+_44729535 1.685 ENSMUST00000174068.1
Jarid2
jumonji, AT rich interactive domain 2
chr7_+_79273201 1.684 ENSMUST00000037315.6
Abhd2
abhydrolase domain containing 2
chr6_-_126645784 1.666 ENSMUST00000055168.3
Kcna1
potassium voltage-gated channel, shaker-related subfamily, member 1
chr14_-_88471396 1.665 ENSMUST00000061628.5
Pcdh20
protocadherin 20
chr6_-_57535422 1.649 ENSMUST00000042766.3
Ppm1k
protein phosphatase 1K (PP2C domain containing)
chr11_+_75532127 1.590 ENSMUST00000127226.1
Slc43a2
solute carrier family 43, member 2
chr15_+_21111452 1.583 ENSMUST00000075132.6
Cdh12
cadherin 12
chr5_+_19907502 1.572 ENSMUST00000101558.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr1_-_158356258 1.572 ENSMUST00000004133.8
Brinp2
bone morphogenic protein/retinoic acid inducible neural-specific 2
chr7_+_103550368 1.539 ENSMUST00000106888.1
Olfr613
olfactory receptor 613
chr17_+_25188380 1.531 ENSMUST00000039734.5
Unkl
unkempt-like (Drosophila)
chr15_-_11037968 1.501 ENSMUST00000058007.5
Rxfp3
relaxin family peptide receptor 3
chr16_+_33684538 1.488 ENSMUST00000126532.1
Heg1
HEG homolog 1 (zebrafish)
chr9_+_54980880 1.425 ENSMUST00000093844.3
Chrna5
cholinergic receptor, nicotinic, alpha polypeptide 5
chrX_+_163911401 1.402 ENSMUST00000140845.1
Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr5_+_66968559 1.401 ENSMUST00000127184.1
Limch1
LIM and calponin homology domains 1
chr2_+_69897220 1.399 ENSMUST00000055758.9
ENSMUST00000112251.2
Ubr3

ubiquitin protein ligase E3 component n-recognin 3

chrX_-_104857228 1.397 ENSMUST00000033575.5
Magee2
melanoma antigen, family E, 2
chr5_-_99252839 1.397 ENSMUST00000168092.1
ENSMUST00000031276.8
Rasgef1b

RasGEF domain family, member 1B

chr2_+_68104671 1.395 ENSMUST00000042456.3
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr3_+_86070915 1.390 ENSMUST00000182666.1
Sh3d19
SH3 domain protein D19
chr6_+_125552948 1.380 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Vwf


Von Willebrand factor homolog


chr3_+_32436376 1.375 ENSMUST00000108242.1
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr6_-_137169710 1.367 ENSMUST00000117919.1
Rerg
RAS-like, estrogen-regulated, growth-inhibitor
chr2_-_144527341 1.356 ENSMUST00000163701.1
ENSMUST00000081982.5
Dzank1

double zinc ribbon and ankyrin repeat domains 1

chr9_-_123678782 1.344 ENSMUST00000170591.1
ENSMUST00000171647.1
Slc6a20a

solute carrier family 6 (neurotransmitter transporter), member 20A

chr7_+_123123870 1.343 ENSMUST00000094053.5
Tnrc6a
trinucleotide repeat containing 6a
chr7_-_73537621 1.342 ENSMUST00000172704.1
Chd2
chromodomain helicase DNA binding protein 2
chr7_-_45103747 1.342 ENSMUST00000003512.7
Fcgrt
Fc receptor, IgG, alpha chain transporter
chrX_+_101640056 1.342 ENSMUST00000119299.1
ENSMUST00000044475.4
Ogt

O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)

chr3_-_146770603 1.342 ENSMUST00000106138.1
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr13_+_42866247 1.339 ENSMUST00000131942.1
Phactr1
phosphatase and actin regulator 1
chr1_+_180109192 1.336 ENSMUST00000143176.1
ENSMUST00000135056.1
Cdc42bpa

CDC42 binding protein kinase alpha

chr8_+_66386292 1.333 ENSMUST00000039540.5
ENSMUST00000110253.2
March1

membrane-associated ring finger (C3HC4) 1

chr16_-_74411292 1.323 ENSMUST00000117200.1
Robo2
roundabout homolog 2 (Drosophila)
chr10_-_25200110 1.304 ENSMUST00000100012.2
Akap7
A kinase (PRKA) anchor protein 7
chr8_-_120228221 1.301 ENSMUST00000183235.1
A330074K22Rik
RIKEN cDNA A330074K22 gene
chr18_-_35215008 1.293 ENSMUST00000091636.3
Lrrtm2
leucine rich repeat transmembrane neuronal 2
chr7_+_64185459 1.292 ENSMUST00000177102.2
ENSMUST00000107519.1
ENSMUST00000137650.1
ENSMUST00000032737.5
ENSMUST00000107515.1
ENSMUST00000144996.1
Trpm1





transient receptor potential cation channel, subfamily M, member 1





chr11_+_23306884 1.284 ENSMUST00000180046.1
Usp34
ubiquitin specific peptidase 34
chr2_-_45112890 1.275 ENSMUST00000076836.6
Zeb2
zinc finger E-box binding homeobox 2
chr5_-_131616599 1.260 ENSMUST00000161804.1
Auts2
autism susceptibility candidate 2
chr5_+_66968416 1.246 ENSMUST00000038188.7
Limch1
LIM and calponin homology domains 1
chrM_+_11734 1.243 ENSMUST00000082418.1
mt-Nd5
mitochondrially encoded NADH dehydrogenase 5
chr2_-_45117349 1.242 ENSMUST00000176438.2
Zeb2
zinc finger E-box binding homeobox 2
chr2_+_4559742 1.240 ENSMUST00000176828.1
Frmd4a
FERM domain containing 4A
chr11_+_101246960 1.222 ENSMUST00000107282.3
Ramp2
receptor (calcitonin) activity modifying protein 2
chr9_-_50739365 1.220 ENSMUST00000117093.1
ENSMUST00000121634.1
Dixdc1

DIX domain containing 1

chr12_-_91849081 1.203 ENSMUST00000167466.1
ENSMUST00000021347.5
ENSMUST00000178462.1
Sel1l


sel-1 suppressor of lin-12-like (C. elegans)


chr9_-_103222063 1.202 ENSMUST00000170904.1
Trf
transferrin
chr10_-_117148474 1.201 ENSMUST00000020381.3
Frs2
fibroblast growth factor receptor substrate 2
chr11_+_75531690 1.199 ENSMUST00000149727.1
ENSMUST00000042561.7
ENSMUST00000108433.1
ENSMUST00000143035.1
Slc43a2



solute carrier family 43, member 2



chr13_+_83732438 1.195 ENSMUST00000182701.1
C130071C03Rik
RIKEN cDNA C130071C03 gene
chr14_-_36935560 1.195 ENSMUST00000183038.1
Ccser2
coiled-coil serine rich 2
chr12_+_117516479 1.193 ENSMUST00000109691.2
Rapgef5
Rap guanine nucleotide exchange factor (GEF) 5
chr6_+_37870786 1.189 ENSMUST00000120428.1
ENSMUST00000031859.7
Trim24

tripartite motif-containing 24

chr2_+_4017727 1.189 ENSMUST00000177457.1
Frmd4a
FERM domain containing 4A
chr5_+_64812336 1.183 ENSMUST00000166409.1
Klf3
Kruppel-like factor 3 (basic)
chr10_+_127420334 1.175 ENSMUST00000171434.1
R3hdm2
R3H domain containing 2
chr4_+_154964117 1.161 ENSMUST00000030931.4
ENSMUST00000070953.4
Pank4

pantothenate kinase 4

chr9_-_15357692 1.158 ENSMUST00000098979.3
ENSMUST00000161132.1
5830418K08Rik

RIKEN cDNA 5830418K08 gene

chr10_+_127420867 1.156 ENSMUST00000064793.6
R3hdm2
R3H domain containing 2
chr10_+_127421124 1.154 ENSMUST00000170336.1
R3hdm2
R3H domain containing 2
chr12_+_55598917 1.142 ENSMUST00000051857.3
Insm2
insulinoma-associated 2
chr6_-_118479237 1.138 ENSMUST00000161170.1
Zfp9
zinc finger protein 9
chr16_-_37384940 1.133 ENSMUST00000114781.1
ENSMUST00000114780.1
Stxbp5l

syntaxin binding protein 5-like

chr6_-_56923927 1.130 ENSMUST00000031793.5
Nt5c3
5'-nucleotidase, cytosolic III
chr6_-_122340499 1.128 ENSMUST00000160843.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr3_+_32436151 1.114 ENSMUST00000029201.7
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr6_+_145934113 1.114 ENSMUST00000032383.7
Sspn
sarcospan
chr1_-_190170671 1.099 ENSMUST00000175916.1
Prox1
prospero-related homeobox 1
chr7_-_80405425 1.097 ENSMUST00000107362.3
ENSMUST00000135306.1
Furin

furin (paired basic amino acid cleaving enzyme)

chr17_-_29007925 1.094 ENSMUST00000009138.5
ENSMUST00000119274.1
Stk38

serine/threonine kinase 38

chr8_-_54724317 1.092 ENSMUST00000129132.2
ENSMUST00000150488.1
ENSMUST00000127511.2
Wdr17


WD repeat domain 17


chr5_-_66514815 1.087 ENSMUST00000161879.1
ENSMUST00000159357.1
Apbb2

amyloid beta (A4) precursor protein-binding, family B, member 2

chr18_+_69593361 1.080 ENSMUST00000114978.2
ENSMUST00000114977.1
Tcf4

transcription factor 4

chr6_+_92092369 1.076 ENSMUST00000113463.1
Nr2c2
nuclear receptor subfamily 2, group C, member 2
chr15_+_92597104 1.071 ENSMUST00000035399.8
Pdzrn4
PDZ domain containing RING finger 4
chr8_-_36249292 1.068 ENSMUST00000065297.5
Lonrf1
LON peptidase N-terminal domain and ring finger 1
chr16_-_63864114 1.066 ENSMUST00000064405.6
Epha3
Eph receptor A3
chr11_+_16752203 1.065 ENSMUST00000102884.3
ENSMUST00000020329.6
Egfr

epidermal growth factor receptor

chr13_-_41273977 1.056 ENSMUST00000163881.1
Gm17364
predicted gene, 17364
chr8_-_26119125 1.054 ENSMUST00000037182.7
Hook3
hook homolog 3 (Drosophila)
chr7_+_126950837 1.050 ENSMUST00000106332.1
Sez6l2
seizure related 6 homolog like 2
chr8_-_54724474 1.040 ENSMUST00000175915.1
Wdr17
WD repeat domain 17
chr1_-_64122256 1.032 ENSMUST00000135075.1
Klf7
Kruppel-like factor 7 (ubiquitous)
chr16_+_38089001 1.028 ENSMUST00000023507.6
Gsk3b
glycogen synthase kinase 3 beta
chr1_-_163725123 1.027 ENSMUST00000159679.1
Mettl11b
methyltransferase like 11B
chr5_-_137684665 1.023 ENSMUST00000100544.4
ENSMUST00000031736.9
ENSMUST00000151839.1
Agfg2


ArfGAP with FG repeats 2


chr10_+_69787431 1.019 ENSMUST00000183240.1
Ank3
ankyrin 3, epithelial
chr8_+_83666827 1.016 ENSMUST00000019608.5
Ptger1
prostaglandin E receptor 1 (subtype EP1)
chr1_+_170308802 1.003 ENSMUST00000056991.5
1700015E13Rik
RIKEN cDNA 1700015E13 gene
chr10_-_62814539 0.997 ENSMUST00000173087.1
ENSMUST00000174121.1
Tet1

tet methylcytosine dioxygenase 1

chr2_-_173276144 0.996 ENSMUST00000139306.1
Pmepa1
prostate transmembrane protein, androgen induced 1
chr4_-_87806296 0.976 ENSMUST00000126353.1
ENSMUST00000149357.1
Mllt3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr3_+_55461758 0.975 ENSMUST00000070418.4
Dclk1
doublecortin-like kinase 1
chr18_-_37969742 0.972 ENSMUST00000166148.1
ENSMUST00000163131.1
ENSMUST00000043437.7
Fchsd1


FCH and double SH3 domains 1


chr2_-_52558539 0.962 ENSMUST00000102760.3
ENSMUST00000102761.2
Cacnb4

calcium channel, voltage-dependent, beta 4 subunit

chr17_+_7170101 0.956 ENSMUST00000024575.6
Rps6ka2
ribosomal protein S6 kinase, polypeptide 2
chr7_+_128688480 0.952 ENSMUST00000118605.1
Inpp5f
inositol polyphosphate-5-phosphatase F
chr11_+_103133303 0.952 ENSMUST00000107037.1
Hexim2
hexamethylene bis-acetamide inducible 2
chr6_+_8520008 0.949 ENSMUST00000162567.1
ENSMUST00000161217.1
Glcci1

glucocorticoid induced transcript 1

chr7_+_35802593 0.945 ENSMUST00000052454.2
E130304I02Rik
RIKEN cDNA E130304I02 gene
chr9_+_96258697 0.944 ENSMUST00000179416.1
Tfdp2
transcription factor Dp 2
chr2_+_23069210 0.940 ENSMUST00000155602.1
Acbd5
acyl-Coenzyme A binding domain containing 5
chr12_+_16653470 0.940 ENSMUST00000111064.1
Ntsr2
neurotensin receptor 2
chr8_+_4238733 0.933 ENSMUST00000110998.2
ENSMUST00000062686.4
Map2k7

mitogen-activated protein kinase kinase 7

chr12_+_81631369 0.932 ENSMUST00000036116.5
Ttc9
tetratricopeptide repeat domain 9
chr5_+_34999111 0.923 ENSMUST00000114283.1
Rgs12
regulator of G-protein signaling 12
chr8_+_107031218 0.917 ENSMUST00000034388.9
Vps4a
vacuolar protein sorting 4a (yeast)
chr12_+_55836365 0.916 ENSMUST00000059250.6
Brms1l
breast cancer metastasis-suppressor 1-like
chr2_+_96318014 0.912 ENSMUST00000135431.1
ENSMUST00000162807.2
Lrrc4c

leucine rich repeat containing 4C

chr17_+_88440711 0.908 ENSMUST00000112238.2
ENSMUST00000155640.1
Foxn2

forkhead box N2

chr8_+_121116163 0.905 ENSMUST00000054691.6
Foxc2
forkhead box C2
chr12_-_24493656 0.905 ENSMUST00000073088.2
Gm16372
predicted pseudogene 16372
chr11_+_103133333 0.904 ENSMUST00000124928.1
ENSMUST00000062530.4
Hexim2

hexamethylene bis-acetamide inducible 2

chr9_+_118478182 0.888 ENSMUST00000111763.1
Eomes
eomesodermin homolog (Xenopus laevis)
chr15_-_33687840 0.888 ENSMUST00000042021.3
Tspyl5
testis-specific protein, Y-encoded-like 5
chr5_+_29195983 0.888 ENSMUST00000160888.1
ENSMUST00000159272.1
ENSMUST00000001247.5
ENSMUST00000161398.1
ENSMUST00000160246.1
Rnf32




ring finger protein 32




chr1_+_180111339 0.888 ENSMUST00000145181.1
Cdc42bpa
CDC42 binding protein kinase alpha
chr18_-_75697639 0.884 ENSMUST00000165559.1
Ctif
CBP80/20-dependent translation initiation factor
chr9_-_123678873 0.883 ENSMUST00000040960.6
Slc6a20a
solute carrier family 6 (neurotransmitter transporter), member 20A
chr2_-_153225396 0.877 ENSMUST00000099194.2
Tspyl3
TSPY-like 3
chr9_+_45370185 0.875 ENSMUST00000085939.6
Fxyd6
FXYD domain-containing ion transport regulator 6
chr2_-_77703252 0.874 ENSMUST00000171063.1
Zfp385b
zinc finger protein 385B
chr7_-_126676357 0.869 ENSMUST00000106371.1
ENSMUST00000106372.3
ENSMUST00000155419.1
Sult1a1


sulfotransferase family 1A, phenol-preferring, member 1



Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 9.6 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) phosphate ion transmembrane transport(GO:0035435) cellular trivalent inorganic anion homeostasis(GO:0072502)
1.4 4.1 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
1.3 3.9 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
1.0 4.0 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.8 2.5 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.7 2.0 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.6 2.6 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.6 2.5 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.6 2.3 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.6 0.6 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.6 1.7 GO:0050975 sensory perception of touch(GO:0050975)
0.6 4.4 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.6 3.3 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.5 2.1 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.5 3.6 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.5 7.7 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.5 1.0 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.5 4.6 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.5 2.4 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.5 1.9 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.5 0.9 GO:0009838 abscission(GO:0009838)
0.5 2.3 GO:0021856 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.4 1.3 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.4 2.2 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.4 1.3 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.4 0.8 GO:2001187 positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.4 1.3 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.4 6.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.4 4.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.4 1.1 GO:0019085 early viral transcription(GO:0019085)
0.3 1.0 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.3 1.9 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.3 2.8 GO:0097475 motor neuron migration(GO:0097475)
0.3 0.9 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) glomerular mesangial cell differentiation(GO:0072008) glomerular mesangial cell development(GO:0072144) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.3 1.1 GO:0090472 dibasic protein processing(GO:0090472)
0.3 6.2 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.3 0.8 GO:1904207 chemokine (C-C motif) ligand 2 secretion(GO:0035926) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.3 0.8 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.3 1.1 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.3 1.8 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.3 2.8 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.2 2.2 GO:0015838 amino-acid betaine transport(GO:0015838)
0.2 0.7 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.2 1.0 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.2 1.2 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.2 1.4 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.2 0.7 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.2 0.7 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.2 0.7 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.2 0.7 GO:1903002 negative regulation of presynaptic membrane organization(GO:1901630) regulation of lipid transport across blood brain barrier(GO:1903000) positive regulation of lipid transport across blood brain barrier(GO:1903002)
0.2 0.8 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.2 1.7 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.2 1.2 GO:0097646 dimeric G-protein coupled receptor signaling pathway(GO:0038042) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.2 0.6 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.2 1.8 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.2 1.0 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.2 1.0 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.2 0.4 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.2 0.4 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.2 0.8 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.2 2.7 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.2 1.2 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.2 3.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.2 0.5 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.2 0.8 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.2 0.5 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.2 1.6 GO:0042118 endothelial cell activation(GO:0042118)
0.2 1.4 GO:0035095 behavioral response to nicotine(GO:0035095)
0.2 0.5 GO:0031038 myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519)
0.2 0.9 GO:0030242 pexophagy(GO:0030242)
0.2 11.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2 1.4 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2 1.7 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.2 0.6 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362) regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter(GO:0072368)
0.1 0.4 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.1 1.8 GO:0032570 response to progesterone(GO:0032570)
0.1 0.7 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.1 1.4 GO:0051923 sulfation(GO:0051923)
0.1 0.8 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.4 GO:0006667 sphinganine metabolic process(GO:0006667) regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.1 0.4 GO:1902605 heterotrimeric G-protein complex assembly(GO:1902605)
0.1 0.6 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 1.9 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.1 1.1 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.1 0.4 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.1 0.8 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.1 0.8 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.1 0.3 GO:1901419 regulation of response to alcohol(GO:1901419) positive regulation of response to alcohol(GO:1901421)
0.1 2.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.6 GO:0035063 nuclear speck organization(GO:0035063)
0.1 1.3 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.1 5.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 3.2 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 0.3 GO:0006953 acute-phase response(GO:0006953)
0.1 1.1 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.2 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 0.7 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 0.2 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.1 0.3 GO:0071336 positive regulation of keratinocyte proliferation(GO:0010838) white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.1 2.1 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 1.8 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.1 1.3 GO:0046548 retinal rod cell development(GO:0046548)
0.1 0.5 GO:0046208 spermine catabolic process(GO:0046208)
0.1 0.5 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 1.4 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 0.6 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.1 0.5 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 0.6 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.5 GO:0072318 clathrin coat disassembly(GO:0072318)
0.1 0.4 GO:2000158 regulation of ubiquitin-specific protease activity(GO:2000152) positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 2.2 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1 4.8 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 0.5 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.1 0.2 GO:0061055 myotome development(GO:0061055)
0.1 0.7 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.1 0.2 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.1 1.0 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 1.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.4 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.1 0.3 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.1 0.6 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 1.9 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.3 GO:0042420 dopamine catabolic process(GO:0042420)
0.1 0.1 GO:2000617 positive regulation of histone H3-K9 acetylation(GO:2000617)
0.1 0.5 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.3 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.1 1.1 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.1 0.8 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 1.0 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 0.9 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.1 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.1 3.1 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 0.7 GO:0032496 response to lipopolysaccharide(GO:0032496)
0.1 0.3 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.1 0.6 GO:0090527 actin filament reorganization(GO:0090527)
0.1 2.9 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.1 0.5 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 1.0 GO:0051382 kinetochore assembly(GO:0051382)
0.1 1.6 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.1 0.4 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 2.0 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 0.2 GO:2001180 negative regulation of interleukin-18 production(GO:0032701) negative regulation of interleukin-10 secretion(GO:2001180)
0.1 0.2 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.1 1.3 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.1 0.8 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 0.5 GO:0072189 ureter development(GO:0072189)
0.1 0.3 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.5 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.1 0.3 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 0.2 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.1 0.3 GO:0033762 response to glucagon(GO:0033762)
0.0 0.7 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.7 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.7 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.8 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 3.0 GO:0015807 L-amino acid transport(GO:0015807)
0.0 0.2 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.6 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.8 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.2 GO:0021592 fourth ventricle development(GO:0021592) initiation of neural tube closure(GO:0021993)
0.0 1.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.3 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.4 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.0 0.7 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.0 1.6 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 1.2 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 1.1 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.0 1.4 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.3 GO:0030035 microspike assembly(GO:0030035)
0.0 1.9 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.4 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.7 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.7 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.9 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.5 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.2 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.1 GO:0060916 mesenchymal cell proliferation involved in lung development(GO:0060916) regulation of mesenchymal cell proliferation involved in lung development(GO:2000790) negative regulation of mesenchymal cell proliferation involved in lung development(GO:2000791)
0.0 1.0 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.0 1.0 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.3 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.2 GO:0036324 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144) vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.0 4.0 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 0.3 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.5 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.7 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 2.5 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 1.4 GO:0008542 visual learning(GO:0008542)
0.0 0.2 GO:0014010 Schwann cell proliferation(GO:0014010)
0.0 0.3 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 3.4 GO:0007416 synapse assembly(GO:0007416)
0.0 1.3 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.1 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.0 0.8 GO:0021799 cerebral cortex radially oriented cell migration(GO:0021799)
0.0 0.9 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.3 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 1.3 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.2 GO:0009301 snRNA transcription(GO:0009301)
0.0 0.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 1.3 GO:0030168 platelet activation(GO:0030168)
0.0 0.1 GO:2000124 endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.2 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.2 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.4 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 0.3 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0045187 regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.9 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.3 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.7 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 0.1 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.2 GO:0001553 luteinization(GO:0001553)
0.0 0.6 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.4 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.0 0.2 GO:0007602 phototransduction(GO:0007602)
0.0 2.0 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.3 GO:0048041 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041)
0.0 1.2 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.5 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.2 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.5 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.0 0.4 GO:1900046 regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)
0.0 0.9 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.2 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.2 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.9 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.4 GO:0034605 cellular response to heat(GO:0034605)
0.0 1.1 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.1 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.0 0.2 GO:0014823 response to activity(GO:0014823)
0.0 1.5 GO:0006275 regulation of DNA replication(GO:0006275)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.6 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.8 2.5 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.5 4.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.5 1.9 GO:0097454 Schwann cell microvillus(GO:0097454)
0.4 6.1 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.3 1.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.3 1.1 GO:0097487 vesicle lumen(GO:0031983) multivesicular body, internal vesicle(GO:0097487)
0.2 1.2 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.2 1.7 GO:0097524 sperm plasma membrane(GO:0097524)
0.2 1.2 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.2 1.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.2 1.2 GO:0070826 paraferritin complex(GO:0070826)
0.2 0.7 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.2 0.6 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.2 2.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.2 4.2 GO:0071565 nBAF complex(GO:0071565)
0.2 1.8 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.2 0.8 GO:0031258 lamellipodium membrane(GO:0031258)
0.2 4.2 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.2 2.4 GO:0051286 cell tip(GO:0051286)
0.2 1.1 GO:0070695 FHF complex(GO:0070695)
0.1 1.3 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.1 1.4 GO:0001739 sex chromatin(GO:0001739)
0.1 5.8 GO:0031672 A band(GO:0031672)
0.1 0.8 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.6 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 1.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 1.0 GO:1990909 Wnt signalosome(GO:1990909)
0.1 0.4 GO:0060187 cell pole(GO:0060187)
0.1 1.3 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.1 0.8 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 8.1 GO:0031594 neuromuscular junction(GO:0031594)
0.1 0.6 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.9 GO:0090543 ESCRT III complex(GO:0000815) Flemming body(GO:0090543)
0.1 1.4 GO:0005614 interstitial matrix(GO:0005614)
0.1 2.8 GO:0097440 apical dendrite(GO:0097440)
0.1 1.5 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 1.2 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 0.6 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 0.4 GO:0031523 Myb complex(GO:0031523)
0.1 0.4 GO:0001533 cornified envelope(GO:0001533)
0.1 6.4 GO:0072562 blood microparticle(GO:0072562)
0.1 1.3 GO:0042588 zymogen granule(GO:0042588)
0.1 1.1 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 0.8 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.4 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 1.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.5 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 1.5 GO:0070822 Sin3-type complex(GO:0070822)
0.1 0.8 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 1.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 1.3 GO:0030673 axolemma(GO:0030673)
0.0 2.3 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.6 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.7 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.9 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.3 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.4 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.3 GO:0097443 sorting endosome(GO:0097443)
0.0 0.7 GO:0031045 dense core granule(GO:0031045)
0.0 1.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.0 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.7 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.6 GO:0097470 ribbon synapse(GO:0097470)
0.0 1.5 GO:0016235 aggresome(GO:0016235)
0.0 1.5 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 3.8 GO:0042641 actomyosin(GO:0042641)
0.0 1.3 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 2.1 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.9 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.8 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.2 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 1.5 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.4 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 4.5 GO:0001726 ruffle(GO:0001726)
0.0 5.2 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 3.0 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.3 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 6.0 GO:0030427 site of polarized growth(GO:0030427)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 1.0 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 1.0 GO:0005819 spindle(GO:0005819)
0.0 0.6 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.5 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.3 GO:0045275 respiratory chain complex III(GO:0045275)
0.0 0.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.2 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 3.9 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.1 GO:0030478 actin cap(GO:0030478)
0.0 2.7 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.8 GO:0043235 receptor complex(GO:0043235)
0.0 1.5 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.1 GO:0043196 varicosity(GO:0043196)
0.0 1.2 GO:0070469 respiratory chain(GO:0070469)
0.0 0.6 GO:0030133 transport vesicle(GO:0030133)
0.0 1.3 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.3 GO:0030175 filopodium(GO:0030175)
0.0 9.8 GO:0031226 intrinsic component of plasma membrane(GO:0031226)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.5 GO:0016592 mediator complex(GO:0016592)
0.0 2.3 GO:0045202 synapse(GO:0045202)
0.0 0.1 GO:0005922 connexon complex(GO:0005922)
0.0 1.0 GO:0005814 centriole(GO:0005814)
0.0 1.0 GO:0030424 axon(GO:0030424)
0.0 1.0 GO:0043005 neuron projection(GO:0043005)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 9.6 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.6 2.6 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.6 3.8 GO:0070699 type II activin receptor binding(GO:0070699)
0.6 4.6 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.6 2.8 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.5 1.4 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.4 1.3 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.4 1.6 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.4 1.5 GO:0004966 galanin receptor activity(GO:0004966)
0.4 1.9 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.4 1.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.3 1.4 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.3 2.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.3 1.0 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.3 2.5 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.3 13.7 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.3 2.2 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.3 2.7 GO:0019865 immunoglobulin binding(GO:0019865)
0.3 2.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.3 3.6 GO:0002162 dystroglycan binding(GO:0002162)
0.2 0.7 GO:0016748 succinyltransferase activity(GO:0016748)
0.2 1.2 GO:0097643 amylin receptor activity(GO:0097643)
0.2 1.7 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2 1.2 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.2 1.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.2 1.9 GO:0097322 7SK snRNA binding(GO:0097322)
0.2 0.7 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.2 1.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 0.7 GO:0046911 hydroxyapatite binding(GO:0046848) metal chelating activity(GO:0046911) phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.2 0.8 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.2 0.8 GO:0001851 complement component C3b binding(GO:0001851)
0.2 2.7 GO:0038191 neuropilin binding(GO:0038191)
0.2 1.0 GO:0004954 icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)
0.2 4.9 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 1.0 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.2 3.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2 0.6 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.2 1.0 GO:0004984 olfactory receptor activity(GO:0004984)
0.2 3.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.2 1.2 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.2 1.2 GO:0034056 estrogen response element binding(GO:0034056)
0.2 0.5 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.2 1.0 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.2 0.5 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.2 0.6 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.2 0.8 GO:0035004 1-phosphatidylinositol-3-kinase activity(GO:0016303) phosphatidylinositol 3-kinase activity(GO:0035004)
0.2 4.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 0.5 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.2 0.6 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 1.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 1.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 1.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.4 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.6 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 1.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 4.8 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 1.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) neurotrophin TRKA receptor binding(GO:0005168)
0.1 0.4 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 3.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 2.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 4.3 GO:0070412 R-SMAD binding(GO:0070412)
0.1 1.3 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.8 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 0.5 GO:0015440 peptide-transporting ATPase activity(GO:0015440)
0.1 1.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.5 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.3 GO:0005118 sevenless binding(GO:0005118)
0.1 0.3 GO:0004534 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160) 5'-3' exoribonuclease activity(GO:0004534)
0.1 1.9 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.4 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.4 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.6 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.8 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 0.4 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 1.0 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 0.3 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.6 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.1 1.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.2 GO:0098809 nitrite reductase activity(GO:0098809)
0.1 0.7 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.3 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 1.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.4 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 1.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 3.6 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 0.7 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.9 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.1 0.3 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 0.2 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 2.4 GO:0032452 histone demethylase activity(GO:0032452)
0.1 1.4 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.9 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.7 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.5 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.4 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.7 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.9 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 1.8 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.7 GO:0051400 BH domain binding(GO:0051400)
0.0 1.4 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 1.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.8 GO:0043422 protein kinase B binding(GO:0043422)
0.0 12.1 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.8 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 1.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.3 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 1.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.9 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 2.0 GO:0030507 spectrin binding(GO:0030507)
0.0 9.5 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 1.5 GO:0004407 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.0 0.3 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 8.1 GO:0008017 microtubule binding(GO:0008017)
0.0 4.1 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.6 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 12.2 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.1 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 0.8 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.4 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 1.3 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.5 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.9 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.6 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 1.1 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.2 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 1.0 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.6 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 1.3 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.7 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 1.0 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 0.3 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.0 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.1 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.0 0.3 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.5 GO:0002039 p53 binding(GO:0002039)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 15.4 PID_ARF6_PATHWAY Arf6 signaling events
0.2 8.4 PID_REELIN_PATHWAY Reelin signaling pathway
0.2 7.7 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.2 4.6 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.1 4.4 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 0.8 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.1 4.3 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.1 1.3 PID_IL3_PATHWAY IL3-mediated signaling events
0.1 0.6 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.1 2.0 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.1 2.9 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 3.7 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 3.5 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 0.5 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 1.1 PID_ERBB4_PATHWAY ErbB4 signaling events
0.0 0.5 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.0 4.2 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.9 PID_ARF_3PATHWAY Arf1 pathway
0.0 1.2 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.8 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.4 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.8 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 1.4 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 1.0 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 1.1 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 0.6 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.9 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.2 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 0.9 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 0.5 PID_CXCR4_PATHWAY CXCR4-mediated signaling events
0.0 0.3 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.0 2.2 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.4 PID_TCR_PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.2 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.2 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.8 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.3 4.1 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.2 6.8 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.2 3.0 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 7.6 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.2 1.4 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.2 1.4 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.2 0.8 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.2 4.2 REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.2 3.3 REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1 5.9 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.1 1.4 REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTERGRINS_ Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 1.1 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 4.8 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.5 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.1 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.1 1.4 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 3.0 REACTOME_CELL_CELL_JUNCTION_ORGANIZATION Genes involved in Cell-cell junction organization
0.1 16.3 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.1 2.4 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.1 0.5 REACTOME_GRB2_EVENTS_IN_ERBB2_SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.1 1.2 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 9.2 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions
0.1 1.3 REACTOME_ACTIVATION_OF_NMDA_RECEPTOR_UPON_GLUTAMATE_BINDING_AND_POSTSYNAPTIC_EVENTS Genes involved in Activation of NMDA receptor upon glutamate binding and postsynaptic events
0.1 0.8 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.2 REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS Genes involved in Prolonged ERK activation events
0.1 0.5 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 1.0 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 2.4 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 0.5 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.1 0.7 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 0.3 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 1.2 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.8 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 1.1 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.9 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.9 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.1 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 1.0 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 1.8 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.6 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.2 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 1.0 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.7 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.3 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.8 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.1 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.6 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.4 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.7 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.6 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 1.1 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.3 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.0 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.6 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.4 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.7 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.7 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.3 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME_ENOS_ACTIVATION_AND_REGULATION Genes involved in eNOS activation and regulation
0.0 0.1 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.1 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.2 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.2 REACTOME_FORMATION_OF_TRANSCRIPTION_COUPLED_NER_TC_NER_REPAIR_COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.1 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 0.5 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors