Motif ID: Hoxd1

Z-value: 0.735


Transcription factors associated with Hoxd1:

Gene SymbolEntrez IDGene Name
Hoxd1 ENSMUSG00000042448.4 Hoxd1



Activity profile for motif Hoxd1.

activity profile for motif Hoxd1


Sorted Z-values histogram for motif Hoxd1

Sorted Z-values for motif Hoxd1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxd1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_85722474 4.008 ENSMUST00000119077.1
Fam160a1
family with sequence similarity 160, member A1
chr17_-_45659312 3.997 ENSMUST00000120717.1
Capn11
calpain 11
chr2_-_20943413 3.898 ENSMUST00000140230.1
Arhgap21
Rho GTPase activating protein 21
chr5_-_62766153 3.115 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr10_-_110000219 3.036 ENSMUST00000032719.7
Nav3
neuron navigator 3
chrX_-_143933089 2.999 ENSMUST00000087313.3
Dcx
doublecortin
chr5_+_107497762 2.814 ENSMUST00000152474.1
ENSMUST00000060553.7
A830010M20Rik

RIKEN cDNA A830010M20 gene

chr17_-_36032682 2.554 ENSMUST00000102678.4
H2-T23
histocompatibility 2, T region locus 23
chr5_+_134932351 2.424 ENSMUST00000047196.7
ENSMUST00000111221.2
ENSMUST00000111219.1
ENSMUST00000068617.5
ENSMUST00000111218.1
ENSMUST00000136246.1
Wbscr27





Williams Beuren syndrome chromosome region 27 (human)





chr16_+_11406618 2.317 ENSMUST00000122168.1
Snx29
sorting nexin 29
chr1_-_158356258 2.246 ENSMUST00000004133.8
Brinp2
bone morphogenic protein/retinoic acid inducible neural-specific 2
chr2_+_3424123 2.219 ENSMUST00000061852.5
ENSMUST00000100463.3
ENSMUST00000102988.3
ENSMUST00000115066.1
Dclre1c



DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae)



chr5_+_107497718 2.171 ENSMUST00000112671.2
A830010M20Rik
RIKEN cDNA A830010M20 gene
chr17_+_88440711 2.156 ENSMUST00000112238.2
ENSMUST00000155640.1
Foxn2

forkhead box N2

chr13_-_105054895 2.128 ENSMUST00000063551.5
Rgs7bp
regulator of G-protein signalling 7 binding protein
chr2_+_116067213 1.985 ENSMUST00000152412.1
G630016G05Rik
RIKEN cDNA G630016G05 gene
chr2_+_69897255 1.938 ENSMUST00000131553.1
Ubr3
ubiquitin protein ligase E3 component n-recognin 3
chr2_+_150323702 1.880 ENSMUST00000133235.2
Gm10130
predicted gene 10130
chr12_+_52699297 1.794 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chr8_-_41041828 1.749 ENSMUST00000051379.7
Mtus1
mitochondrial tumor suppressor 1
chr2_+_170731807 1.727 ENSMUST00000029075.4
Dok5
docking protein 5
chr2_-_116067391 1.727 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr18_+_37355271 1.711 ENSMUST00000051163.1
Pcdhb8
protocadherin beta 8
chr9_-_123851855 1.684 ENSMUST00000184082.1
ENSMUST00000167595.2
Fyco1

FYVE and coiled-coil domain containing 1

chr9_-_55919605 1.682 ENSMUST00000037408.8
Scaper
S phase cyclin A-associated protein in the ER
chr9_-_15301555 1.678 ENSMUST00000034414.8
4931406C07Rik
RIKEN cDNA 4931406C07 gene
chr16_-_55934845 1.678 ENSMUST00000121129.1
ENSMUST00000023270.7
Cep97

centrosomal protein 97

chr1_+_65186727 1.676 ENSMUST00000097707.4
ENSMUST00000081154.7
Pikfyve

phosphoinositide kinase, FYVE finger containing

chr12_-_98577940 1.602 ENSMUST00000110113.1
Kcnk10
potassium channel, subfamily K, member 10
chr16_-_55934797 1.583 ENSMUST00000122280.1
ENSMUST00000121703.2
Cep97

centrosomal protein 97

chr3_-_116712644 1.582 ENSMUST00000029569.2
Slc35a3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chrM_+_9870 1.579 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr2_+_121956651 1.577 ENSMUST00000110574.1
Ctdspl2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr5_-_70842617 1.569 ENSMUST00000031119.1
Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr5_-_123012874 1.556 ENSMUST00000172729.1
Kdm2b
lysine (K)-specific demethylase 2B
chr11_+_35121126 1.550 ENSMUST00000069837.3
Slit3
slit homolog 3 (Drosophila)
chr5_-_106926245 1.508 ENSMUST00000117588.1
Hfm1
HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
chr7_+_127511976 1.500 ENSMUST00000098025.4
Srcap
Snf2-related CREBBP activator protein
chr2_-_177267036 1.492 ENSMUST00000108963.1
Gm14409
predicted gene 14409
chr13_+_83732438 1.468 ENSMUST00000182701.1
C130071C03Rik
RIKEN cDNA C130071C03 gene
chr13_+_42866247 1.404 ENSMUST00000131942.1
Phactr1
phosphatase and actin regulator 1
chrX_-_143933204 1.392 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chr8_-_122915987 1.384 ENSMUST00000098333.4
Ankrd11
ankyrin repeat domain 11
chr1_-_24612700 1.383 ENSMUST00000088336.1
Gm10222
predicted gene 10222
chr2_-_156392829 1.363 ENSMUST00000088578.2
2900097C17Rik
RIKEN cDNA 2900097C17 gene
chr8_-_105966038 1.308 ENSMUST00000116429.2
ENSMUST00000034370.9
Slc12a4

solute carrier family 12, member 4

chrM_+_10167 1.283 ENSMUST00000082414.1
mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr9_-_85749308 1.279 ENSMUST00000039213.8
Ibtk
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr10_+_90071095 1.275 ENSMUST00000183109.1
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr7_+_29816061 1.219 ENSMUST00000032796.6
ENSMUST00000178162.1
Zfp790

zinc finger protein 790

chr6_-_57535422 1.185 ENSMUST00000042766.3
Ppm1k
protein phosphatase 1K (PP2C domain containing)
chr15_-_8710409 1.181 ENSMUST00000157065.1
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr13_+_44121167 1.173 ENSMUST00000163056.1
ENSMUST00000159595.1
Gm5083

predicted gene 5083

chr17_-_32822200 1.152 ENSMUST00000179695.1
Zfp799
zinc finger protein 799
chr1_-_33814516 1.126 ENSMUST00000044455.5
ENSMUST00000115167.1
Zfp451

zinc finger protein 451

chr2_+_121956411 1.122 ENSMUST00000110578.1
Ctdspl2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr6_+_34029421 1.115 ENSMUST00000070189.3
ENSMUST00000101564.2
Lrguk

leucine-rich repeats and guanylate kinase domain containing

chr19_+_8802486 1.097 ENSMUST00000172175.1
Zbtb3
zinc finger and BTB domain containing 3
chr2_+_69897220 1.087 ENSMUST00000055758.9
ENSMUST00000112251.2
Ubr3

ubiquitin protein ligase E3 component n-recognin 3

chr8_+_113635787 1.045 ENSMUST00000035777.8
Mon1b
MON1 homolog b (yeast)
chr6_+_72097561 1.042 ENSMUST00000069994.4
ENSMUST00000114112.1
St3gal5

ST3 beta-galactoside alpha-2,3-sialyltransferase 5

chr8_+_113635550 1.033 ENSMUST00000179926.1
Mon1b
MON1 homolog b (yeast)
chr12_+_80644212 0.975 ENSMUST00000085245.5
Slc39a9
solute carrier family 39 (zinc transporter), member 9
chr9_-_107872403 0.957 ENSMUST00000183035.1
Rbm6
RNA binding motif protein 6
chr2_+_65620829 0.947 ENSMUST00000028377.7
Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr15_+_82256023 0.936 ENSMUST00000143238.1
1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr8_-_54724474 0.932 ENSMUST00000175915.1
Wdr17
WD repeat domain 17
chr9_+_72958785 0.923 ENSMUST00000098567.2
ENSMUST00000034734.8
Dyx1c1

dyslexia susceptibility 1 candidate 1 homolog (human)

chr7_+_79273201 0.902 ENSMUST00000037315.6
Abhd2
abhydrolase domain containing 2
chr4_+_103143052 0.900 ENSMUST00000106855.1
Mier1
mesoderm induction early response 1 homolog (Xenopus laevis
chr17_+_34931253 0.881 ENSMUST00000007253.5
Neu1
neuraminidase 1
chr15_+_98092569 0.878 ENSMUST00000163507.1
Pfkm
phosphofructokinase, muscle
chr5_+_29195983 0.876 ENSMUST00000160888.1
ENSMUST00000159272.1
ENSMUST00000001247.5
ENSMUST00000161398.1
ENSMUST00000160246.1
Rnf32




ring finger protein 32




chr11_+_32283511 0.860 ENSMUST00000093209.3
Hba-a1
hemoglobin alpha, adult chain 1
chr18_+_59062462 0.855 ENSMUST00000058633.2
ENSMUST00000175897.1
ENSMUST00000118510.1
ENSMUST00000175830.1
A730017C20Rik



RIKEN cDNA A730017C20 gene



chr16_-_16600533 0.842 ENSMUST00000159542.1
Fgd4
FYVE, RhoGEF and PH domain containing 4
chr3_+_94837702 0.818 ENSMUST00000107266.1
ENSMUST00000042402.5
ENSMUST00000107269.1
Pogz


pogo transposable element with ZNF domain


chr13_-_67332525 0.812 ENSMUST00000168892.1
ENSMUST00000109735.2
Zfp595

zinc finger protein 595

chr14_+_69347587 0.807 ENSMUST00000064831.5
Entpd4
ectonucleoside triphosphate diphosphohydrolase 4
chr11_-_107337556 0.802 ENSMUST00000040380.6
Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chr19_-_32196393 0.796 ENSMUST00000151822.1
Sgms1
sphingomyelin synthase 1
chr2_+_109917639 0.788 ENSMUST00000046548.7
ENSMUST00000111037.2
Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chr4_+_146610961 0.785 ENSMUST00000130825.1
Gm13248
predicted gene 13248
chr15_+_25773985 0.783 ENSMUST00000125667.1
Myo10
myosin X
chr14_-_104522615 0.765 ENSMUST00000022716.2
Rnf219
ring finger protein 219
chr7_+_130774069 0.762 ENSMUST00000048453.5
Btbd16
BTB (POZ) domain containing 16
chr7_-_6730412 0.752 ENSMUST00000051209.4
Peg3
paternally expressed 3
chr18_+_31609512 0.737 ENSMUST00000164667.1
B930094E09Rik
RIKEN cDNA B930094E09 gene
chr5_-_118244861 0.730 ENSMUST00000117177.1
ENSMUST00000133372.1
ENSMUST00000154786.1
ENSMUST00000121369.1
Rnft2



ring finger protein, transmembrane 2



chr7_-_44929410 0.730 ENSMUST00000107857.3
ENSMUST00000085399.6
ENSMUST00000167930.1
ENSMUST00000166972.1
Ap2a1



adaptor-related protein complex 2, alpha 1 subunit



chr14_+_48446128 0.729 ENSMUST00000124720.1
Tmem260
transmembrane protein 260
chrX_+_16619698 0.727 ENSMUST00000026013.5
Maoa
monoamine oxidase A
chr2_-_45117349 0.717 ENSMUST00000176438.2
Zeb2
zinc finger E-box binding homeobox 2
chr2_+_37516618 0.705 ENSMUST00000065441.6
Gpr21
G protein-coupled receptor 21
chr10_-_117148474 0.698 ENSMUST00000020381.3
Frs2
fibroblast growth factor receptor substrate 2
chr6_+_149582012 0.641 ENSMUST00000144085.2
Gm21814
predicted gene, 21814
chr14_-_75754475 0.623 ENSMUST00000049168.7
Cog3
component of oligomeric golgi complex 3
chr12_+_16653470 0.578 ENSMUST00000111064.1
Ntsr2
neurotensin receptor 2
chr18_+_12741324 0.577 ENSMUST00000115857.2
ENSMUST00000121018.1
ENSMUST00000119108.1
Cabyr


calcium-binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2)


chr7_-_140154712 0.565 ENSMUST00000059241.7
Sprn
shadow of prion protein
chr18_-_60273267 0.550 ENSMUST00000090260.4
Gm4841
predicted gene 4841
chr4_+_147132038 0.549 ENSMUST00000084149.3
Gm13139
predicted gene 13139
chr17_-_57031468 0.544 ENSMUST00000007814.8
Khsrp
KH-type splicing regulatory protein
chr11_-_121388186 0.543 ENSMUST00000106107.2
Rab40b
Rab40b, member RAS oncogene family
chr9_-_86880647 0.533 ENSMUST00000167014.1
Snap91
synaptosomal-associated protein 91
chr12_+_72441852 0.531 ENSMUST00000162159.1
Lrrc9
leucine rich repeat containing 9
chr3_+_94837533 0.518 ENSMUST00000107270.2
Pogz
pogo transposable element with ZNF domain
chr18_+_59062282 0.504 ENSMUST00000165666.2
A730017C20Rik
RIKEN cDNA A730017C20 gene
chrX_-_75578188 0.494 ENSMUST00000033545.5
Rab39b
RAB39B, member RAS oncogene family
chr12_-_24493656 0.491 ENSMUST00000073088.2
Gm16372
predicted pseudogene 16372
chr17_-_32886083 0.479 ENSMUST00000178401.1
Zfp870
zinc finger protein 870
chr4_-_132075250 0.447 ENSMUST00000105970.1
ENSMUST00000105975.1
Epb4.1

erythrocyte protein band 4.1

chr2_+_131491764 0.438 ENSMUST00000028806.5
ENSMUST00000110179.2
ENSMUST00000110189.2
ENSMUST00000110182.2
ENSMUST00000110183.2
ENSMUST00000110186.2
ENSMUST00000110188.1
Smox






spermine oxidase






chr9_-_119341390 0.437 ENSMUST00000139870.1
Myd88
myeloid differentiation primary response gene 88
chr10_-_120112946 0.436 ENSMUST00000020449.5
Helb
helicase (DNA) B
chr12_+_72441933 0.402 ENSMUST00000161284.1
Lrrc9
leucine rich repeat containing 9
chr5_-_63968867 0.401 ENSMUST00000154169.1
Rell1
RELT-like 1
chrX_+_9885622 0.389 ENSMUST00000067529.2
ENSMUST00000086165.3
Sytl5

synaptotagmin-like 5

chr12_-_87388317 0.387 ENSMUST00000021424.4
Sptlc2
serine palmitoyltransferase, long chain base subunit 2
chr16_-_45724600 0.381 ENSMUST00000096057.4
Tagln3
transgelin 3
chr14_+_25980039 0.374 ENSMUST00000173155.1
Duxbl1
double homeobox B-like 1
chr10_+_75037066 0.367 ENSMUST00000147802.1
ENSMUST00000020391.5
Rab36

RAB36, member RAS oncogene family

chr15_+_98571004 0.362 ENSMUST00000023728.6
4930415O20Rik
RIKEN cDNA 4930415O20 gene
chr2_-_84715160 0.352 ENSMUST00000035840.5
Zdhhc5
zinc finger, DHHC domain containing 5
chr2_-_160619971 0.341 ENSMUST00000109473.1
Gm14221
predicted gene 14221
chr18_-_24603464 0.333 ENSMUST00000154205.1
Slc39a6
solute carrier family 39 (metal ion transporter), member 6
chr14_+_26259109 0.325 ENSMUST00000174494.1
Duxbl3
double homeobox B-like 3
chr5_+_145204523 0.323 ENSMUST00000085671.3
ENSMUST00000031601.7
Zkscan5

zinc finger with KRAB and SCAN domains 5

chr16_+_52031549 0.319 ENSMUST00000114471.1
Cblb
Casitas B-lineage lymphoma b
chr2_-_73580288 0.312 ENSMUST00000028515.3
Chrna1
cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
chr10_+_103367748 0.289 ENSMUST00000074204.4
ENSMUST00000179636.1
Slc6a15

solute carrier family 6 (neurotransmitter transporter), member 15

chr14_+_26119811 0.277 ENSMUST00000173617.1
Duxbl2
doubl homeobox B-like 2
chr4_+_147492417 0.263 ENSMUST00000105721.2
Gm13152
predicted gene 13152
chr15_-_8710734 0.258 ENSMUST00000005493.7
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr13_-_56895737 0.253 ENSMUST00000022023.6
ENSMUST00000109871.1
Trpc7

transient receptor potential cation channel, subfamily C, member 7

chr14_+_55559993 0.245 ENSMUST00000117236.1
Dcaf11
DDB1 and CUL4 associated factor 11
chr4_+_102570065 0.232 ENSMUST00000097950.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr18_+_24603952 0.219 ENSMUST00000025120.6
Elp2
elongator acetyltransferase complex subunit 2
chr19_+_3323301 0.215 ENSMUST00000025835.4
Cpt1a
carnitine palmitoyltransferase 1a, liver
chr19_-_37330613 0.212 ENSMUST00000131070.1
Ide
insulin degrading enzyme
chr2_-_69712461 0.204 ENSMUST00000102706.3
ENSMUST00000073152.6
Fastkd1

FAST kinase domains 1

chr3_+_103739366 0.179 ENSMUST00000106852.1
Gm10964
predicted gene 10964
chr10_-_86011833 0.166 ENSMUST00000105304.1
ENSMUST00000061699.5
Bpifc

BPI fold containing family C

chr8_+_72219726 0.165 ENSMUST00000003123.8
Fam32a
family with sequence similarity 32, member A
chr17_+_36837123 0.164 ENSMUST00000179968.1
ENSMUST00000130367.1
ENSMUST00000130801.1
ENSMUST00000144182.1
ENSMUST00000123715.1
ENSMUST00000053434.8
Trim26





tripartite motif-containing 26





chr16_+_65520503 0.162 ENSMUST00000176330.1
ENSMUST00000004964.8
ENSMUST00000176038.1
Pou1f1


POU domain, class 1, transcription factor 1


chr16_+_18836573 0.156 ENSMUST00000055413.6
2510002D24Rik
RIKEN cDNA 2510002D24 gene
chr3_-_41742471 0.140 ENSMUST00000026866.8
Sclt1
sodium channel and clathrin linker 1
chr4_-_147809788 0.137 ENSMUST00000105734.3
ENSMUST00000176201.1
Gm13157
Gm20707
predicted gene 13157
predicted gene 20707
chr11_-_45955183 0.109 ENSMUST00000109254.1
Thg1l
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr9_+_119341487 0.080 ENSMUST00000175743.1
ENSMUST00000176397.1
Acaa1a

acetyl-Coenzyme A acyltransferase 1A

chr16_+_34690548 0.054 ENSMUST00000023532.6
Ccdc14
coiled-coil domain containing 14
chr2_-_150255591 0.053 ENSMUST00000063463.5
Gm21994
predicted gene 21994
chr2_+_119047129 0.049 ENSMUST00000153300.1
ENSMUST00000028799.5
Casc5

cancer susceptibility candidate 5

chr10_-_76110956 0.042 ENSMUST00000120757.1
Slc5a4b
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr1_-_185329331 0.032 ENSMUST00000027921.4
ENSMUST00000110975.1
ENSMUST00000110974.3
Iars2


isoleucine-tRNA synthetase 2, mitochondrial


chr10_+_116143881 0.031 ENSMUST00000105271.2
Ptprr
protein tyrosine phosphatase, receptor type, R
chr1_-_33814591 0.023 ENSMUST00000019861.6
Zfp451
zinc finger protein 451
chr19_-_6067785 0.023 ENSMUST00000162575.1
ENSMUST00000159084.1
ENSMUST00000161718.1
ENSMUST00000162810.1
ENSMUST00000025713.5
ENSMUST00000113543.2
ENSMUST00000161528.1
Tm7sf2






transmembrane 7 superfamily member 2






chr2_+_172370658 0.021 ENSMUST00000151511.1
ENSMUST00000116375.1
Cstf1

cleavage stimulation factor, 3' pre-RNA, subunit 1

chr10_+_116018213 0.018 ENSMUST00000063470.4
Ptprr
protein tyrosine phosphatase, receptor type, R

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:2000564 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.8 3.9 GO:0051684 maintenance of Golgi location(GO:0051684)
0.8 3.0 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.7 2.1 GO:0019085 early viral transcription(GO:0019085)
0.4 1.8 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.4 1.1 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
0.4 1.4 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.3 1.7 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.3 1.6 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.3 1.6 GO:0021993 initiation of neural tube closure(GO:0021993)
0.3 4.4 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.3 2.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.3 0.8 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.3 1.5 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.3 3.3 GO:1902018 regulation of mitotic spindle assembly(GO:1901673) negative regulation of cilium assembly(GO:1902018)
0.2 0.7 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.2 0.7 GO:0042420 dopamine catabolic process(GO:0042420)
0.2 0.9 GO:0006689 ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.2 0.7 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.2 1.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.9 GO:0061622 glycolytic process through glucose-1-phosphate(GO:0061622)
0.1 0.4 GO:2000338 positive regulation of interleukin-23 production(GO:0032747) chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.1 1.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.7 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.1 0.4 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 1.7 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.1 0.9 GO:0080184 response to stilbenoid(GO:0035634) response to phenylpropanoid(GO:0080184)
0.1 1.3 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 0.3 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.1 0.8 GO:0030035 microspike assembly(GO:0030035)
0.1 0.4 GO:0046208 spermine catabolic process(GO:0046208)
0.1 0.9 GO:0036159 outer dynein arm assembly(GO:0036158) inner dynein arm assembly(GO:0036159)
0.1 1.3 GO:0051382 kinetochore assembly(GO:0051382)
0.1 1.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 1.5 GO:0048240 sperm capacitation(GO:0048240)
0.1 0.5 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.1 2.4 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.1 1.7 GO:0032288 myelin assembly(GO:0032288)
0.1 1.7 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.1 0.3 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 1.6 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.5 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.1 0.2 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.1 0.6 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.1 0.3 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 2.2 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.6 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 1.3 GO:0006829 zinc II ion transport(GO:0006829)
0.0 1.6 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 1.1 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.8 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.2 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 1.4 GO:0060325 face morphogenesis(GO:0060325)
0.0 2.2 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.5 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 0.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.2 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.7 GO:0040018 positive regulation of multicellular organism growth(GO:0040018)
0.0 0.6 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 1.3 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209) negative regulation of sequestering of calcium ion(GO:0051283)
0.0 0.3 GO:0006828 manganese ion transport(GO:0006828)
0.0 1.4 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.8 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.0 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 1.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.0 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.6 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0097637 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.2 0.9 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.2 0.9 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.2 2.6 GO:0042612 MHC class I protein complex(GO:0042612)
0.2 2.2 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.2 0.5 GO:0098835 presynaptic endosome(GO:0098830) presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.1 0.9 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 1.1 GO:0002177 manchette(GO:0002177)
0.1 1.8 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 1.7 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.4 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.8 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 0.4 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.7 GO:0032433 filopodium tip(GO:0032433)
0.0 4.0 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.6 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.6 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 1.6 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.6 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.3 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 2.4 GO:0005776 autophagosome(GO:0005776)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 1.6 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.9 GO:0016235 aggresome(GO:0016235)
0.0 4.4 GO:0030426 growth cone(GO:0030426)
0.0 1.6 GO:0030175 filopodium(GO:0030175)
0.0 0.2 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.1 GO:0071439 clathrin complex(GO:0071439)
0.0 0.5 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.6 GO:0043198 dendritic shaft(GO:0043198)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.3 2.6 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.2 2.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.2 1.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.2 0.9 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.2 0.9 GO:0031720 haptoglobin binding(GO:0031720)
0.2 4.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 1.7 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.2 1.5 GO:0048495 Roundabout binding(GO:0048495)
0.2 1.3 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.2 0.7 GO:0051378 primary amine oxidase activity(GO:0008131) serotonin binding(GO:0051378)
0.2 0.7 GO:0004952 dopamine neurotransmitter receptor activity(GO:0004952)
0.2 1.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.2 0.8 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.4 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.1 1.6 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 1.8 GO:0043495 protein anchor(GO:0043495)
0.1 0.4 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.8 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.1 0.4 GO:0070976 TIR domain binding(GO:0070976)
0.1 2.9 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.4 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.1 1.6 GO:0050811 GABA-A receptor activity(GO:0004890) GABA receptor binding(GO:0050811)
0.1 1.6 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.8 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.7 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.9 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 1.6 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.1 0.8 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 3.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 1.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 1.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.5 GO:0035615 clathrin heavy chain binding(GO:0032050) clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.0 GO:0005402 cation:sugar symporter activity(GO:0005402)
0.0 0.2 GO:0043559 insulin binding(GO:0043559)
0.0 1.7 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.3 GO:0005283 sodium:amino acid symporter activity(GO:0005283) L-proline transmembrane transporter activity(GO:0015193)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.6 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 1.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.7 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.5 GO:0031489 myosin V binding(GO:0031489)
0.0 3.9 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.9 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.7 GO:0070412 R-SMAD binding(GO:0070412)
0.0 1.1 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.8 GO:0030507 spectrin binding(GO:0030507)
0.0 3.9 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.6 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 3.5 GO:0008017 microtubule binding(GO:0008017)
0.0 2.3 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.9 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 0.0 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.4 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 2.2 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 3.1 PID_ARF6_PATHWAY Arf6 signaling events
0.0 2.4 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.7 PID_ARF_3PATHWAY Arf1 pathway
0.0 0.8 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.2 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.0 1.3 PID_BCR_5PATHWAY BCR signaling pathway
0.0 0.4 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.8 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.0 0.3 PID_CD40_PATHWAY CD40/CD40L signaling
0.0 0.3 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.0 2.2 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 1.5 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 1.7 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 0.7 REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 0.4 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.7 REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS Genes involved in Prolonged ERK activation events
0.0 2.6 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.3 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 5.1 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions
0.0 1.6 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.3 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.2 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.4 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.5 REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 3.8 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.9 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.0 0.7 REACTOME_SPHINGOLIPID_METABOLISM Genes involved in Sphingolipid metabolism
0.0 0.3 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers