Motif ID: Ikzf2

Z-value: 0.654


Transcription factors associated with Ikzf2:

Gene SymbolEntrez IDGene Name
Ikzf2 ENSMUSG00000025997.7 Ikzf2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ikzf2mm10_v2_chr1_-_69685937_696859660.019.4e-01Click!


Activity profile for motif Ikzf2.

activity profile for motif Ikzf2


Sorted Z-values histogram for motif Ikzf2

Sorted Z-values for motif Ikzf2



Network of associatons between targets according to the STRING database.



First level regulatory network of Ikzf2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_+_103422010 5.019 ENSMUST00000182089.1
Gm26992
predicted gene, 26992
chr15_+_3270767 2.651 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
Sepp1



selenoprotein P, plasma, 1



chr2_-_71546745 1.979 ENSMUST00000024159.6
Dlx2
distal-less homeobox 2
chr3_-_116129615 1.832 ENSMUST00000029574.8
Vcam1
vascular cell adhesion molecule 1
chr6_-_23248264 1.641 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr11_-_55419898 1.542 ENSMUST00000108858.1
ENSMUST00000141530.1
Sparc

secreted acidic cysteine rich glycoprotein

chr5_-_123141067 1.507 ENSMUST00000162697.1
ENSMUST00000160321.1
ENSMUST00000159637.1
AI480526


expressed sequence AI480526


chr1_-_45503282 1.344 ENSMUST00000086430.4
Col5a2
collagen, type V, alpha 2
chr6_+_15185203 1.280 ENSMUST00000154448.1
Foxp2
forkhead box P2
chr6_+_4003926 1.274 ENSMUST00000031670.8
Gng11
guanine nucleotide binding protein (G protein), gamma 11
chr12_+_75308308 1.206 ENSMUST00000118602.1
ENSMUST00000118966.1
ENSMUST00000055390.5
Rhoj


ras homolog gene family, member J


chrX_+_106920618 1.075 ENSMUST00000060576.7
Lpar4
lysophosphatidic acid receptor 4
chr1_+_45311538 0.986 ENSMUST00000087883.6
Col3a1
collagen, type III, alpha 1
chr5_+_30913398 0.940 ENSMUST00000031055.5
Emilin1
elastin microfibril interfacer 1
chr3_+_159839729 0.936 ENSMUST00000068952.5
Wls
wntless homolog (Drosophila)
chr13_-_103764502 0.919 ENSMUST00000074616.5
Srek1
splicing regulatory glutamine/lysine-rich protein 1
chr3_+_88214474 0.877 ENSMUST00000181356.1
ENSMUST00000181396.1
Gm3764

predicted gene 3764

chr16_+_30065333 0.868 ENSMUST00000023171.7
Hes1
hairy and enhancer of split 1 (Drosophila)
chr4_+_105157339 0.865 ENSMUST00000064139.7
Ppap2b
phosphatidic acid phosphatase type 2B
chr19_+_55894508 0.815 ENSMUST00000142291.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr5_+_92897981 0.747 ENSMUST00000113051.2
Shroom3
shroom family member 3
chr14_+_54936456 0.656 ENSMUST00000037814.6
Cmtm5
CKLF-like MARVEL transmembrane domain containing 5
chr3_-_154330543 0.653 ENSMUST00000184966.1
ENSMUST00000177846.2
Lhx8

LIM homeobox protein 8

chr5_-_134747241 0.651 ENSMUST00000015138.9
Eln
elastin
chr9_-_42944479 0.648 ENSMUST00000114865.1
Grik4
glutamate receptor, ionotropic, kainate 4
chr2_+_103970221 0.630 ENSMUST00000111140.2
ENSMUST00000111139.2
Lmo2

LIM domain only 2

chr1_-_162866502 0.629 ENSMUST00000046049.7
Fmo1
flavin containing monooxygenase 1
chr14_+_64589802 0.622 ENSMUST00000180610.1
A930011O12Rik
RIKEN cDNA A930011O12 gene
chr3_-_106001474 0.589 ENSMUST00000066319.6
Pifo
primary cilia formation
chr9_-_13446753 0.562 ENSMUST00000167906.2
Gm17571
predicted gene, 17571
chr2_+_103970115 0.558 ENSMUST00000111143.1
ENSMUST00000138815.1
Lmo2

LIM domain only 2

chr2_-_77170592 0.545 ENSMUST00000164114.2
ENSMUST00000049544.7
Ccdc141

coiled-coil domain containing 141

chr4_-_92191749 0.543 ENSMUST00000123179.1
Gm12666
predicted gene 12666
chr17_-_56571438 0.533 ENSMUST00000131056.1
Safb2
scaffold attachment factor B2
chr19_+_5689131 0.520 ENSMUST00000004156.8
Map3k11
mitogen-activated protein kinase kinase kinase 11
chr7_-_139582790 0.498 ENSMUST00000106095.2
Nkx6-2
NK6 homeobox 2
chr5_-_123140135 0.489 ENSMUST00000160099.1
AI480526
expressed sequence AI480526
chr16_+_90727490 0.477 ENSMUST00000181232.1
Gm17518
predicted gene, 17518
chr11_+_94211431 0.475 ENSMUST00000041589.5
Tob1
transducer of ErbB-2.1
chr11_+_23020464 0.460 ENSMUST00000094363.3
ENSMUST00000151877.1
Fam161a

family with sequence similarity 161, member A

chr8_-_89147247 0.451 ENSMUST00000177870.1
Gm6625
predicted gene 6625
chr5_+_110330697 0.448 ENSMUST00000112481.1
Pole
polymerase (DNA directed), epsilon
chr3_+_84925476 0.448 ENSMUST00000107675.1
Fbxw7
F-box and WD-40 domain protein 7
chr9_+_70207342 0.441 ENSMUST00000034745.7
Myo1e
myosin IE
chrX_+_71556874 0.428 ENSMUST00000123100.1
Hmgb3
high mobility group box 3
chr14_+_47663756 0.420 ENSMUST00000022391.7
Ktn1
kinectin 1
chrX_-_134600976 0.415 ENSMUST00000033621.6
Gla
galactosidase, alpha
chr16_-_95459245 0.404 ENSMUST00000176345.1
ENSMUST00000121809.2
ENSMUST00000118113.1
ENSMUST00000122199.1
Erg



avian erythroblastosis virus E-26 (v-ets) oncogene related



chr1_-_87394721 0.383 ENSMUST00000113212.3
Kcnj13
potassium inwardly-rectifying channel, subfamily J, member 13
chr8_-_80739497 0.370 ENSMUST00000043359.8
Smarca5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr2_-_72980402 0.368 ENSMUST00000066003.6
ENSMUST00000102689.3
Sp3

trans-acting transcription factor 3

chr5_+_42067960 0.366 ENSMUST00000087332.4
Gm16223
predicted gene 16223
chr4_+_57637816 0.324 ENSMUST00000150412.1
Gm20459
predicted gene 20459
chrX_+_109095359 0.314 ENSMUST00000033598.8
Sh3bgrl
SH3-binding domain glutamic acid-rich protein like
chr11_-_84525514 0.310 ENSMUST00000018842.7
Lhx1
LIM homeobox protein 1
chr19_+_41593363 0.290 ENSMUST00000099454.3
AI606181
expressed sequence AI606181
chr3_-_33844255 0.289 ENSMUST00000029222.5
Ccdc39
coiled-coil domain containing 39
chr13_+_44731265 0.288 ENSMUST00000173246.1
Jarid2
jumonji, AT rich interactive domain 2
chr19_-_29812952 0.280 ENSMUST00000099525.3
Ranbp6
RAN binding protein 6
chr11_+_49609263 0.272 ENSMUST00000020617.2
Flt4
FMS-like tyrosine kinase 4
chr9_-_52168111 0.268 ENSMUST00000165519.1
Zc3h12c
zinc finger CCCH type containing 12C
chr10_+_58394381 0.256 ENSMUST00000105468.1
Lims1
LIM and senescent cell antigen-like domains 1
chr3_-_95995662 0.249 ENSMUST00000123006.1
Plekho1
pleckstrin homology domain containing, family O member 1
chr3_-_95995999 0.223 ENSMUST00000015889.3
Plekho1
pleckstrin homology domain containing, family O member 1
chr2_-_26409161 0.220 ENSMUST00000145701.1
Inpp5e
inositol polyphosphate-5-phosphatase E
chr9_+_64385675 0.220 ENSMUST00000068967.4
Megf11
multiple EGF-like-domains 11
chr8_-_67818284 0.216 ENSMUST00000120071.1
Psd3
pleckstrin and Sec7 domain containing 3
chr12_+_64965742 0.212 ENSMUST00000066296.7
Fam179b
family with sequence similarity 179, member B
chr13_-_54590047 0.209 ENSMUST00000148222.1
ENSMUST00000026987.5
Nop16

NOP16 nucleolar protein

chr19_-_42202150 0.200 ENSMUST00000018966.7
Sfrp5
secreted frizzled-related sequence protein 5
chr12_+_98771018 0.198 ENSMUST00000021399.7
Zc3h14
zinc finger CCCH type containing 14
chr16_-_90727329 0.195 ENSMUST00000099554.4
Mis18a
MIS18 kinetochore protein homolog A (S. pombe)
chr8_+_128685654 0.192 ENSMUST00000090006.5
Itgb1
integrin beta 1 (fibronectin receptor beta)
chr5_-_88527841 0.188 ENSMUST00000087033.3
Igj
immunoglobulin joining chain
chr2_+_97467657 0.182 ENSMUST00000059049.7
Lrrc4c
leucine rich repeat containing 4C
chr2_-_140671462 0.178 ENSMUST00000110057.2
Flrt3
fibronectin leucine rich transmembrane protein 3
chr3_-_95995698 0.168 ENSMUST00000130043.1
Plekho1
pleckstrin homology domain containing, family O member 1
chr11_-_115491796 0.166 ENSMUST00000106530.1
ENSMUST00000021082.6
Nt5c

5',3'-nucleotidase, cytosolic

chr8_-_61591130 0.160 ENSMUST00000135439.1
ENSMUST00000121200.1
Palld

palladin, cytoskeletal associated protein

chr7_-_84679346 0.159 ENSMUST00000069537.2
ENSMUST00000178385.1
Zfand6

zinc finger, AN1-type domain 6

chr4_+_141239499 0.156 ENSMUST00000141834.2
Arhgef19
Rho guanine nucleotide exchange factor (GEF) 19
chrX_-_153037549 0.151 ENSMUST00000051484.3
Mageh1
melanoma antigen, family H, 1
chr9_+_53537021 0.148 ENSMUST00000035850.7
Npat
nuclear protein in the AT region
chr2_-_140671400 0.139 ENSMUST00000056760.3
Flrt3
fibronectin leucine rich transmembrane protein 3
chr1_+_63445842 0.139 ENSMUST00000087374.3
ENSMUST00000114107.1
ENSMUST00000182642.1
Adam23


a disintegrin and metallopeptidase domain 23


chrX_+_134601179 0.133 ENSMUST00000074950.4
ENSMUST00000113203.1
ENSMUST00000113202.1
Hnrnph2


heterogeneous nuclear ribonucleoprotein H2


chr7_-_4778141 0.131 ENSMUST00000094892.5
Il11
interleukin 11
chr3_-_95995835 0.123 ENSMUST00000143485.1
Plekho1
pleckstrin homology domain containing, family O member 1
chr14_-_54409469 0.116 ENSMUST00000000984.4
Slc7a7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr13_+_89540636 0.103 ENSMUST00000022108.7
Hapln1
hyaluronan and proteoglycan link protein 1
chr7_-_134232125 0.100 ENSMUST00000127524.1
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr1_-_69685937 0.096 ENSMUST00000027146.2
Ikzf2
IKAROS family zinc finger 2
chr4_+_130107556 0.096 ENSMUST00000030563.5
Pef1
penta-EF hand domain containing 1
chr3_-_65529355 0.095 ENSMUST00000099076.3
4931440P22Rik
RIKEN cDNA 4931440P22 gene
chr2_-_26409100 0.093 ENSMUST00000114090.1
Inpp5e
inositol polyphosphate-5-phosphatase E
chr2_+_174330006 0.089 ENSMUST00000109085.1
ENSMUST00000109087.1
ENSMUST00000109084.1
Gnas


GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus


chr11_+_29463735 0.082 ENSMUST00000155854.1
Ccdc88a
coiled coil domain containing 88A
chr10_+_58394361 0.077 ENSMUST00000020077.4
Lims1
LIM and senescent cell antigen-like domains 1
chr4_-_14621494 0.076 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chr12_+_76324860 0.076 ENSMUST00000095610.2
ENSMUST00000154078.2
Akap5

A kinase (PRKA) anchor protein 5

chr18_-_15151427 0.069 ENSMUST00000025992.6
Kctd1
potassium channel tetramerisation domain containing 1
chr8_-_67818218 0.068 ENSMUST00000059374.4
Psd3
pleckstrin and Sec7 domain containing 3
chr12_+_76324905 0.066 ENSMUST00000172992.1
Akap5
A kinase (PRKA) anchor protein 5
chr13_+_44731281 0.050 ENSMUST00000174086.1
Jarid2
jumonji, AT rich interactive domain 2
chr17_-_46440099 0.047 ENSMUST00000166852.1
Gm5093
predicted gene 5093
chrX_+_134601271 0.039 ENSMUST00000050331.6
ENSMUST00000059297.5
Hnrnph2

heterogeneous nuclear ribonucleoprotein H2

chr13_+_54590204 0.034 ENSMUST00000026986.6
Higd2a
HIG1 domain family, member 2A
chr6_+_59208870 0.025 ENSMUST00000062626.3
Tigd2
tigger transposable element derived 2
chr3_-_108017877 0.024 ENSMUST00000004140.4
Gstm1
glutathione S-transferase, mu 1
chr5_-_51567717 0.020 ENSMUST00000127135.1
ENSMUST00000151104.1
Ppargc1a

peroxisome proliferative activated receptor, gamma, coactivator 1 alpha

chr11_+_115765420 0.016 ENSMUST00000093912.4
ENSMUST00000136720.1
ENSMUST00000103034.3
ENSMUST00000141871.1
2310067B10Rik



RIKEN cDNA 2310067B10 gene



chr14_-_54605908 0.016 ENSMUST00000022786.4
4931414P19Rik
RIKEN cDNA 4931414P19 gene
chr10_+_21993890 0.014 ENSMUST00000092673.4
Sgk1
serum/glucocorticoid regulated kinase 1
chr10_+_25359798 0.011 ENSMUST00000053748.8
Epb4.1l2
erythrocyte protein band 4.1-like 2
chr5_+_53590453 0.010 ENSMUST00000113865.1
Rbpj
recombination signal binding protein for immunoglobulin kappa J region
chr4_-_129578535 0.006 ENSMUST00000052835.8
Fam167b
family with sequence similarity 167, member B
chr7_-_134232005 0.006 ENSMUST00000134504.1
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr5_-_104021919 0.005 ENSMUST00000031251.9
Hsd17b11
hydroxysteroid (17-beta) dehydrogenase 11
chr5_+_107437908 0.001 ENSMUST00000094541.2
Btbd8
BTB (POZ) domain containing 8
chr3_+_76075583 0.001 ENSMUST00000160261.1
Fstl5
follistatin-like 5

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0061075 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.4 1.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.3 0.9 GO:0061357 Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356) positive regulation of Wnt protein secretion(GO:0061357)
0.3 0.9 GO:0021557 oculomotor nerve development(GO:0021557)
0.3 1.6 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2 0.2 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.2 1.0 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 1.8 GO:0061032 visceral serous pericardium development(GO:0061032)
0.1 0.4 GO:0045004 DNA replication proofreading(GO:0045004)
0.1 1.3 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 0.5 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.3 GO:0072284 cervix development(GO:0060067) metanephric S-shaped body morphogenesis(GO:0072284) anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.1 0.8 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 1.2 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.1 1.2 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 0.4 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 0.4 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.1 0.4 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) positive regulation of blood vessel remodeling(GO:2000504)
0.1 0.2 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.1 0.4 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.1 0.5 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 0.3 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 0.2 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.1 0.4 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 0.7 GO:0031441 negative regulation of mRNA 3'-end processing(GO:0031441)
0.1 0.6 GO:0009404 toxin metabolic process(GO:0009404)
0.1 0.4 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 1.1 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.3 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.8 GO:0051451 myoblast migration(GO:0051451)
0.0 0.2 GO:0006244 pyrimidine nucleotide catabolic process(GO:0006244) pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.0 0.3 GO:0090037 regulation of blood vessel remodeling(GO:0060312) positive regulation of protein kinase C signaling(GO:0090037)
0.0 0.1 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.0 1.5 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.0 0.2 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.9 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.1 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.3 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.7 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739) amylase secretion(GO:0036394) positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.3 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.1 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.5 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.1 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.4 GO:0010107 potassium ion import(GO:0010107)
0.0 0.5 GO:0051642 centrosome localization(GO:0051642)
0.0 0.7 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.0 0.7 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.3 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0019532 oxalate transport(GO:0019532)
0.0 0.2 GO:0003334 keratinocyte development(GO:0003334)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0005588 collagen type V trimer(GO:0005588)
0.4 1.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.2 0.7 GO:0071953 elastic fiber(GO:0071953)
0.1 0.4 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 1.0 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.8 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 0.7 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 0.6 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 0.8 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 0.4 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 0.4 GO:0032437 cuticular plate(GO:0032437)
0.1 0.2 GO:0034679 integrin alpha2-beta1 complex(GO:0034666) integrin alpha3-beta1 complex(GO:0034667) integrin alpha9-beta1 complex(GO:0034679)
0.1 0.9 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 2.0 GO:0002102 podosome(GO:0002102)
0.0 1.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.4 GO:0016589 NURF complex(GO:0016589)
0.0 1.1 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.1 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.5 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.5 GO:0032391 photoreceptor connecting cilium(GO:0032391)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.8 GO:0008131 primary amine oxidase activity(GO:0008131)
0.2 1.1 GO:0098634 protein binding involved in cell-matrix adhesion(GO:0098634)
0.2 1.1 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.4 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 0.5 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.3 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 1.0 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.1 0.4 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 3.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.4 GO:0016936 galactoside binding(GO:0016936)
0.0 2.1 GO:0070888 E-box binding(GO:0070888)
0.0 0.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.8 GO:0070016 gamma-catenin binding(GO:0045295) armadillo repeat domain binding(GO:0070016)
0.0 1.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.6 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 2.2 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.4 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.2 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 2.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253) pyrimidine nucleotide binding(GO:0019103)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.1 1.1 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.1 2.3 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.3 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 1.3 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 3.1 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.7 PID_REELIN_PATHWAY Reelin signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.1 2.0 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 2.3 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.3 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.3 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.6 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.6 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.9 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.3 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.6 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.1 REACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.3 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.2 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.4 REACTOME_SPHINGOLIPID_METABOLISM Genes involved in Sphingolipid metabolism
0.0 0.4 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.6 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere