Motif ID: Hmga1

Z-value: 1.275


Transcription factors associated with Hmga1:

Gene SymbolEntrez IDGene Name
Hmga1 ENSMUSG00000046711.9 Hmga1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hmga1mm10_v2_chr17_+_27556668_275566900.067.0e-01Click!


Activity profile for motif Hmga1.

activity profile for motif Hmga1


Sorted Z-values histogram for motif Hmga1

Sorted Z-values for motif Hmga1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hmga1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_23248264 27.080 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr3_+_102010138 6.032 ENSMUST00000066187.4
Nhlh2
nescient helix loop helix 2
chr15_-_56694525 5.976 ENSMUST00000050544.7
Has2
hyaluronan synthase 2
chr17_+_43953191 5.857 ENSMUST00000044792.4
Rcan2
regulator of calcineurin 2
chr16_-_26989974 5.511 ENSMUST00000089832.4
Gmnc
geminin coiled-coil domain containing
chr10_-_33624587 4.965 ENSMUST00000160299.1
ENSMUST00000019920.6
Clvs2

clavesin 2

chr10_-_92165159 4.550 ENSMUST00000182567.1
ENSMUST00000181604.2
ENSMUST00000181213.1
Rmst


rhabdomyosarcoma 2 associated transcript (non-coding RNA)


chr1_-_158814469 4.443 ENSMUST00000161589.2
Pappa2
pappalysin 2
chr17_+_43952999 4.320 ENSMUST00000177857.1
Rcan2
regulator of calcineurin 2
chr1_+_107511416 4.133 ENSMUST00000009356.4
Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr12_+_52699297 4.016 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chr4_-_36056726 3.950 ENSMUST00000108124.3
Lingo2
leucine rich repeat and Ig domain containing 2
chr10_+_96136603 3.791 ENSMUST00000074615.6
Gm5426
predicted pseudogene 5426
chr12_+_72441933 3.742 ENSMUST00000161284.1
Lrrc9
leucine rich repeat containing 9
chrX_-_103483205 3.506 ENSMUST00000127786.2
Xist
inactive X specific transcripts
chr12_-_108003594 3.423 ENSMUST00000066060.4
Bcl11b
B cell leukemia/lymphoma 11B
chr8_+_45658666 3.262 ENSMUST00000134675.1
ENSMUST00000139869.1
ENSMUST00000126067.1
Sorbs2


sorbin and SH3 domain containing 2


chr8_+_45658731 3.236 ENSMUST00000143820.1
ENSMUST00000132139.1
Sorbs2

sorbin and SH3 domain containing 2

chr8_-_87959560 3.195 ENSMUST00000109655.2
Zfp423
zinc finger protein 423
chr2_+_125866107 3.018 ENSMUST00000134337.1
ENSMUST00000094604.2
ENSMUST00000134798.1
Galk2


galactokinase 2


chr8_+_45658273 2.854 ENSMUST00000153798.1
Sorbs2
sorbin and SH3 domain containing 2
chr18_-_62741387 2.799 ENSMUST00000097557.3
Spink13
serine peptidase inhibitor, Kazal type 13
chr4_+_101507947 2.754 ENSMUST00000149047.1
ENSMUST00000106929.3
Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr6_-_136875794 2.727 ENSMUST00000032342.1
Mgp
matrix Gla protein
chr12_+_72441852 2.680 ENSMUST00000162159.1
Lrrc9
leucine rich repeat containing 9
chr19_-_24861828 2.543 ENSMUST00000047666.4
Pgm5
phosphoglucomutase 5
chr13_-_56895737 2.466 ENSMUST00000022023.6
ENSMUST00000109871.1
Trpc7

transient receptor potential cation channel, subfamily C, member 7

chr6_-_25690729 2.438 ENSMUST00000054867.6
Gpr37
G protein-coupled receptor 37
chr5_-_66514815 2.436 ENSMUST00000161879.1
ENSMUST00000159357.1
Apbb2

amyloid beta (A4) precursor protein-binding, family B, member 2

chr18_+_35770318 2.397 ENSMUST00000165299.1
Gm16490
predicted gene 16490
chr14_+_74640840 2.361 ENSMUST00000036653.3
Htr2a
5-hydroxytryptamine (serotonin) receptor 2A
chr1_-_52499980 2.332 ENSMUST00000164747.1
Nab1
Ngfi-A binding protein 1
chr7_-_28302238 2.318 ENSMUST00000108315.3
Dll3
delta-like 3 (Drosophila)
chr18_+_20665250 2.269 ENSMUST00000075312.3
Ttr
transthyretin
chr3_-_121171678 2.214 ENSMUST00000170781.1
ENSMUST00000039761.5
ENSMUST00000106467.1
ENSMUST00000106466.3
ENSMUST00000164925.2
Rwdd3




RWD domain containing 3




chrX_+_155262443 2.119 ENSMUST00000026324.9
Acot9
acyl-CoA thioesterase 9
chr13_+_5861489 2.105 ENSMUST00000000080.6
Klf6
Kruppel-like factor 6
chr1_+_45311538 2.033 ENSMUST00000087883.6
Col3a1
collagen, type III, alpha 1
chr11_-_42000284 1.976 ENSMUST00000109292.2
ENSMUST00000109290.1
Gabrg2

gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2

chr5_-_103100054 1.975 ENSMUST00000112848.1
Mapk10
mitogen-activated protein kinase 10
chr6_+_13871517 1.926 ENSMUST00000181090.1
ENSMUST00000181225.1
1110019D14Rik

RIKEN cDNA 1110019D14 gene

chr7_-_84679346 1.923 ENSMUST00000069537.2
ENSMUST00000178385.1
Zfand6

zinc finger, AN1-type domain 6

chr4_-_97584605 1.893 ENSMUST00000107067.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr6_-_102464667 1.836 ENSMUST00000032159.6
Cntn3
contactin 3
chr1_-_89933290 1.823 ENSMUST00000036954.7
Gbx2
gastrulation brain homeobox 2
chr11_-_42000532 1.782 ENSMUST00000070735.3
Gabrg2
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr1_-_52490736 1.780 ENSMUST00000170269.1
Nab1
Ngfi-A binding protein 1
chr2_-_62483637 1.774 ENSMUST00000136686.1
ENSMUST00000102733.3
Gcg

glucagon

chr3_-_120886691 1.767 ENSMUST00000182099.1
ENSMUST00000183168.1
ENSMUST00000183276.1
ENSMUST00000182124.1
6530403H02Rik



RIKEN cDNA 6530403H02 gene



chr3_+_124321031 1.735 ENSMUST00000058994.4
Tram1l1
translocation associated membrane protein 1-like 1
chr1_+_66364623 1.730 ENSMUST00000077355.5
ENSMUST00000114012.1
Map2

microtubule-associated protein 2

chr7_-_143460989 1.729 ENSMUST00000167912.1
ENSMUST00000037287.6
Cdkn1c

cyclin-dependent kinase inhibitor 1C (P57)

chr1_+_109993982 1.727 ENSMUST00000027542.6
Cdh7
cadherin 7, type 2
chr10_+_102158858 1.724 ENSMUST00000138522.1
ENSMUST00000163753.1
ENSMUST00000138016.1
Mgat4c


mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)


chr3_+_134236483 1.703 ENSMUST00000181904.1
ENSMUST00000053048.9
Cxxc4

CXXC finger 4

chr6_+_88724828 1.668 ENSMUST00000089449.2
Mgll
monoglyceride lipase
chr12_-_41485751 1.640 ENSMUST00000043884.4
Lrrn3
leucine rich repeat protein 3, neuronal
chr2_-_79908389 1.580 ENSMUST00000090756.4
Pde1a
phosphodiesterase 1A, calmodulin-dependent
chrX_+_163911401 1.578 ENSMUST00000140845.1
Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr6_+_142414012 1.539 ENSMUST00000141548.1
B230216G23Rik
RIKEN cDNA B230216G23 gene
chr11_-_120348513 1.531 ENSMUST00000071555.6
Actg1
actin, gamma, cytoplasmic 1
chr19_+_24875679 1.514 ENSMUST00000073080.5
Gm10053
predicted gene 10053
chr6_-_99632376 1.509 ENSMUST00000176255.1
Gm20696
predicted gene 20696
chr1_+_17145357 1.486 ENSMUST00000026879.7
Gdap1
ganglioside-induced differentiation-associated-protein 1
chr14_-_48667508 1.473 ENSMUST00000144465.1
ENSMUST00000133479.1
ENSMUST00000119070.1
ENSMUST00000152018.1
Otx2



orthodenticle homolog 2 (Drosophila)



chr15_+_61987034 1.471 ENSMUST00000159338.1
Myc
myelocytomatosis oncogene
chr2_+_71981184 1.442 ENSMUST00000090826.5
ENSMUST00000102698.3
Rapgef4

Rap guanine nucleotide exchange factor (GEF) 4

chr1_-_155417283 1.426 ENSMUST00000027741.5
Xpr1
xenotropic and polytropic retrovirus receptor 1
chr4_-_97584612 1.389 ENSMUST00000107068.2
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr1_+_180109192 1.385 ENSMUST00000143176.1
ENSMUST00000135056.1
Cdc42bpa

CDC42 binding protein kinase alpha

chr4_+_21727726 1.361 ENSMUST00000102997.1
ENSMUST00000120679.1
ENSMUST00000108240.2
Ccnc


cyclin C


chr1_+_180101144 1.356 ENSMUST00000133890.1
Cdc42bpa
CDC42 binding protein kinase alpha
chr2_-_73660401 1.347 ENSMUST00000102677.4
Chn1
chimerin (chimaerin) 1
chr9_-_101251810 1.330 ENSMUST00000075941.5
Ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr10_+_97565436 1.318 ENSMUST00000038160.4
Lum
lumican
chr9_+_113812547 1.298 ENSMUST00000166734.2
ENSMUST00000111838.2
ENSMUST00000163895.2
Clasp2


CLIP associating protein 2


chr3_+_76593550 1.291 ENSMUST00000162471.1
Fstl5
follistatin-like 5
chr1_-_155417394 1.266 ENSMUST00000111775.1
ENSMUST00000111774.1
Xpr1

xenotropic and polytropic retrovirus receptor 1

chr1_-_140183283 1.261 ENSMUST00000111977.1
Cfh
complement component factor h
chr11_-_120348475 1.161 ENSMUST00000062147.7
ENSMUST00000128055.1
Actg1

actin, gamma, cytoplasmic 1

chr2_-_140671462 1.143 ENSMUST00000110057.2
Flrt3
fibronectin leucine rich transmembrane protein 3
chr1_-_126830632 1.125 ENSMUST00000112583.1
ENSMUST00000094609.3
Nckap5

NCK-associated protein 5

chrX_-_17571563 1.117 ENSMUST00000177213.1
Fundc1
FUN14 domain containing 1
chr1_+_15712303 1.084 ENSMUST00000170146.1
Kcnb2
potassium voltage gated channel, Shab-related subfamily, member 2
chr1_+_4808237 1.081 ENSMUST00000131119.1
Lypla1
lysophospholipase 1
chr15_-_101054399 1.071 ENSMUST00000178140.1
Fignl2
fidgetin-like 2
chr6_-_30693676 1.063 ENSMUST00000169422.1
ENSMUST00000115131.1
ENSMUST00000115130.2
ENSMUST00000031810.8
Cep41



centrosomal protein 41



chr7_-_60005101 1.053 ENSMUST00000059305.10
Snrpn
small nuclear ribonucleoprotein N
chr3_-_104864420 1.046 ENSMUST00000094028.5
Capza1
capping protein (actin filament) muscle Z-line, alpha 1
chr17_+_45555693 1.031 ENSMUST00000024742.7
Nfkbie
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon
chr18_+_37400845 1.030 ENSMUST00000057228.1
Pcdhb9
protocadherin beta 9
chr6_-_13839916 1.014 ENSMUST00000060442.7
Gpr85
G protein-coupled receptor 85
chr8_-_54718664 1.009 ENSMUST00000144711.2
ENSMUST00000093510.2
Wdr17

WD repeat domain 17

chr1_-_162898665 1.006 ENSMUST00000111510.1
ENSMUST00000045902.6
Fmo2

flavin containing monooxygenase 2

chr5_+_14514918 1.003 ENSMUST00000030691.10
ENSMUST00000182407.1
Pclo

piccolo (presynaptic cytomatrix protein)

chr1_+_152954966 1.003 ENSMUST00000043313.8
Nmnat2
nicotinamide nucleotide adenylyltransferase 2
chrX_+_112604274 0.993 ENSMUST00000071814.6
Zfp711
zinc finger protein 711
chr3_-_20242173 0.974 ENSMUST00000001921.1
Cpa3
carboxypeptidase A3, mast cell
chr1_-_140183404 0.969 ENSMUST00000066859.6
ENSMUST00000111976.2
Cfh

complement component factor h

chr9_+_57521232 0.958 ENSMUST00000000090.6
Cox5a
cytochrome c oxidase subunit Va
chr8_+_40307458 0.955 ENSMUST00000068999.7
Micu3
mitochondrial calcium uptake family, member 3
chrM_+_10167 0.951 ENSMUST00000082414.1
mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chrX_-_136741155 0.944 ENSMUST00000166930.1
ENSMUST00000113095.1
ENSMUST00000155207.1
ENSMUST00000080411.6
ENSMUST00000169418.1
Morf4l2




mortality factor 4 like 2




chr5_+_33018816 0.940 ENSMUST00000019109.7
Ywhah
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr2_-_140671440 0.940 ENSMUST00000099301.1
Flrt3
fibronectin leucine rich transmembrane protein 3
chr9_-_101198999 0.931 ENSMUST00000066773.7
Ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr4_+_109676568 0.924 ENSMUST00000102724.4
Faf1
Fas-associated factor 1
chr14_+_26514554 0.924 ENSMUST00000104927.1
Gm2178
predicted gene 2178
chr6_+_86849488 0.887 ENSMUST00000089519.6
ENSMUST00000113668.1
Aak1

AP2 associated kinase 1

chr2_-_140671400 0.885 ENSMUST00000056760.3
Flrt3
fibronectin leucine rich transmembrane protein 3
chr10_+_34297421 0.882 ENSMUST00000047935.6
Tspyl4
TSPY-like 4
chr3_-_108536466 0.860 ENSMUST00000048012.6
ENSMUST00000106626.2
ENSMUST00000106625.3
5330417C22Rik


RIKEN cDNA 5330417C22 gene


chr12_+_55089202 0.859 ENSMUST00000021407.10
Srp54a
signal recognition particle 54A
chr11_+_108682602 0.855 ENSMUST00000106718.3
ENSMUST00000106715.1
ENSMUST00000106724.3
Cep112


centrosomal protein 112


chrX_-_70365052 0.836 ENSMUST00000101509.2
Ids
iduronate 2-sulfatase
chr11_+_101582236 0.833 ENSMUST00000039581.7
ENSMUST00000100403.2
ENSMUST00000107194.1
ENSMUST00000128614.1
Tmem106a



transmembrane protein 106A



chr6_+_91684061 0.824 ENSMUST00000032185.7
Slc6a6
solute carrier family 6 (neurotransmitter transporter, taurine), member 6
chr5_+_121777929 0.823 ENSMUST00000160821.1
Atxn2
ataxin 2
chr3_+_95588928 0.812 ENSMUST00000177390.1
ENSMUST00000098861.4
ENSMUST00000060323.5
Golph3l


golgi phosphoprotein 3-like


chr6_+_17743582 0.807 ENSMUST00000000674.6
ENSMUST00000077080.2
St7

suppression of tumorigenicity 7

chr4_-_123750236 0.801 ENSMUST00000102636.3
Akirin1
akirin 1
chr7_-_126704816 0.798 ENSMUST00000032949.7
Coro1a
coronin, actin binding protein 1A
chrX_-_43274786 0.791 ENSMUST00000016294.7
Tenm1
teneurin transmembrane protein 1
chr6_-_59024470 0.787 ENSMUST00000089860.5
Fam13a
family with sequence similarity 13, member A
chr12_+_59131473 0.786 ENSMUST00000177162.1
Ctage5
CTAGE family, member 5
chr15_+_77084367 0.783 ENSMUST00000181870.1
1700109K24Rik
RIKEN cDNA 1700109K24 gene
chr10_+_127420867 0.772 ENSMUST00000064793.6
R3hdm2
R3H domain containing 2
chr11_-_107189325 0.763 ENSMUST00000018577.7
ENSMUST00000106757.1
Nol11

nucleolar protein 11

chr7_-_126704736 0.761 ENSMUST00000131415.1
Coro1a
coronin, actin binding protein 1A
chr2_-_36136773 0.754 ENSMUST00000028251.3
Rbm18
RNA binding motif protein 18
chr4_+_49059256 0.752 ENSMUST00000076670.2
E130309F12Rik
RIKEN cDNA E130309F12 gene
chrX_-_163761323 0.748 ENSMUST00000059320.2
Rnf138rt1
ring finger protein 138, retrogene 1
chr1_+_180111339 0.747 ENSMUST00000145181.1
Cdc42bpa
CDC42 binding protein kinase alpha
chr7_+_34251038 0.744 ENSMUST00000105172.1
Gm6096
predicted gene 6096
chr15_+_41830921 0.728 ENSMUST00000166917.1
Oxr1
oxidation resistance 1
chr1_-_150465563 0.723 ENSMUST00000164600.1
ENSMUST00000111902.2
ENSMUST00000111901.2
ENSMUST00000006171.9
Prg4



proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)



chr2_-_73660351 0.708 ENSMUST00000154258.1
Chn1
chimerin (chimaerin) 1
chr16_-_59632520 0.704 ENSMUST00000118438.1
Arl6
ADP-ribosylation factor-like 6
chr18_-_34579072 0.704 ENSMUST00000079287.5
Nme5
NME/NM23 family member 5
chr18_+_37513652 0.703 ENSMUST00000061405.4
Pcdhb21
protocadherin beta 21
chr6_-_59024340 0.696 ENSMUST00000173193.1
Fam13a
family with sequence similarity 13, member A
chr14_-_46788267 0.694 ENSMUST00000015903.4
Cnih1
cornichon homolog 1 (Drosophila)
chr7_+_7171330 0.684 ENSMUST00000051435.7
Zfp418
zinc finger protein 418
chr15_-_100424092 0.664 ENSMUST00000154676.1
Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr9_+_75071579 0.662 ENSMUST00000136731.1
Myo5a
myosin VA
chrX_-_17572241 0.655 ENSMUST00000176638.1
ENSMUST00000026016.6
Fundc1

FUN14 domain containing 1

chr18_-_12121460 0.649 ENSMUST00000055447.6
ENSMUST00000050228.7
ENSMUST00000092075.4
Tmem241


transmembrane protein 241


chr3_+_97901190 0.649 ENSMUST00000029476.2
ENSMUST00000122288.1
Sec22b

SEC22 vesicle trafficking protein homolog B (S. cerevisiae)

chrX_-_23285532 0.644 ENSMUST00000115319.2
Klhl13
kelch-like 13
chrX_+_18162575 0.626 ENSMUST00000044484.6
ENSMUST00000052368.8
Kdm6a

lysine (K)-specific demethylase 6A

chr9_-_100506844 0.626 ENSMUST00000112874.3
Nck1
non-catalytic region of tyrosine kinase adaptor protein 1
chr13_+_18717289 0.626 ENSMUST00000072961.4
Vps41
vacuolar protein sorting 41 (yeast)
chr18_+_36952621 0.619 ENSMUST00000115661.2
Pcdha2
protocadherin alpha 2
chr15_+_41447438 0.617 ENSMUST00000110297.2
ENSMUST00000090096.4
Oxr1

oxidation resistance 1

chr9_+_80066939 0.615 ENSMUST00000164859.1
Senp6
SUMO/sentrin specific peptidase 6
chr8_+_65967157 0.598 ENSMUST00000072482.6
March1
membrane-associated ring finger (C3HC4) 1
chrM_+_9870 0.596 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr19_-_37178011 0.594 ENSMUST00000133988.1
Cpeb3
cytoplasmic polyadenylation element binding protein 3
chr6_+_17636983 0.590 ENSMUST00000015877.7
Capza2
capping protein (actin filament) muscle Z-line, alpha 2
chr12_+_64917901 0.583 ENSMUST00000058135.4
Gm527
predicted gene 527
chr9_+_80066895 0.580 ENSMUST00000037484.8
ENSMUST00000176640.1
Senp6

SUMO/sentrin specific peptidase 6

chrX_+_159303266 0.573 ENSMUST00000112491.1
Rps6ka3
ribosomal protein S6 kinase polypeptide 3
chr6_+_17693905 0.568 ENSMUST00000115420.1
St7
suppression of tumorigenicity 7
chr3_-_88772578 0.568 ENSMUST00000090945.4
Syt11
synaptotagmin XI
chr5_-_5266038 0.563 ENSMUST00000115451.1
ENSMUST00000115452.1
ENSMUST00000131392.1
Cdk14


cyclin-dependent kinase 14


chr9_+_32116040 0.562 ENSMUST00000174641.1
Arhgap32
Rho GTPase activating protein 32
chr8_-_111854278 0.560 ENSMUST00000034432.5
Cfdp1
craniofacial development protein 1
chr12_+_59131286 0.556 ENSMUST00000176464.1
ENSMUST00000170992.2
ENSMUST00000176322.1
Ctage5


CTAGE family, member 5


chr17_+_28692568 0.552 ENSMUST00000114752.1
Mapk14
mitogen-activated protein kinase 14
chr5_+_8046077 0.550 ENSMUST00000088786.4
Sri
sorcin
chr14_-_26971232 0.547 ENSMUST00000036570.4
Appl1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr8_+_109778554 0.546 ENSMUST00000093157.6
Ap1g1
adaptor protein complex AP-1, gamma 1 subunit
chr2_-_91182848 0.536 ENSMUST00000111370.2
ENSMUST00000111376.1
ENSMUST00000099723.2
Madd


MAP-kinase activating death domain


chr5_+_130187158 0.534 ENSMUST00000119027.1
ENSMUST00000026390.7
Rabgef1

RAB guanine nucleotide exchange factor (GEF) 1

chr4_-_40279389 0.531 ENSMUST00000108108.2
ENSMUST00000095128.3
Ndufb6

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6

chr14_+_113314602 0.530 ENSMUST00000072359.6
Tpm3-rs7
tropomyosin 3, related sequence 7
chr13_-_114388057 0.517 ENSMUST00000022286.6
Ndufs4
NADH dehydrogenase (ubiquinone) Fe-S protein 4
chr14_-_52104015 0.515 ENSMUST00000111610.4
ENSMUST00000164655.1
Hnrnpc

heterogeneous nuclear ribonucleoprotein C

chr7_-_113347273 0.514 ENSMUST00000117577.1
Btbd10
BTB (POZ) domain containing 10
chr18_+_37736897 0.512 ENSMUST00000091935.4
Pcdhga9
protocadherin gamma subfamily A, 9
chr13_+_21495218 0.504 ENSMUST00000104942.1
AK157302
cDNA sequence AK157302
chr3_-_129755305 0.504 ENSMUST00000029653.2
Egf
epidermal growth factor
chr12_+_98771018 0.498 ENSMUST00000021399.7
Zc3h14
zinc finger CCCH type containing 14
chr6_-_125191535 0.490 ENSMUST00000043848.4
Ncapd2
non-SMC condensin I complex, subunit D2
chr1_-_171150588 0.486 ENSMUST00000155798.1
ENSMUST00000081560.4
ENSMUST00000111336.3
Sdhc


succinate dehydrogenase complex, subunit C, integral membrane protein


chr15_+_31276491 0.474 ENSMUST00000068987.5
Fam136b-ps
family with sequence similarity 136, member B, pseudogene
chrM_+_3906 0.472 ENSMUST00000082396.1
mt-Nd2
mitochondrially encoded NADH dehydrogenase 2
chr2_-_9878580 0.460 ENSMUST00000102976.3
Gata3
GATA binding protein 3
chr15_+_82345954 0.459 ENSMUST00000023086.8
Smdt1
single-pass membrane protein with aspartate rich tail 1
chr10_+_127266256 0.452 ENSMUST00000026479.9
Dctn2
dynactin 2
chr3_+_28263205 0.442 ENSMUST00000159236.2
Tnik
TRAF2 and NCK interacting kinase
chr8_+_120488416 0.435 ENSMUST00000034279.9
Gse1
genetic suppressor element 1
chr5_-_124578992 0.433 ENSMUST00000128920.1
Eif2b1
eukaryotic translation initiation factor 2B, subunit 1 (alpha)
chr5_-_124579045 0.431 ENSMUST00000135361.1
ENSMUST00000031334.8
Eif2b1

eukaryotic translation initiation factor 2B, subunit 1 (alpha)

chr9_+_58582397 0.429 ENSMUST00000176557.1
ENSMUST00000114121.4
ENSMUST00000177064.1
Nptn


neuroplastin


chr11_+_52232009 0.418 ENSMUST00000037324.5
ENSMUST00000166537.1
Skp1a

S-phase kinase-associated protein 1A

chr7_-_83550258 0.415 ENSMUST00000177929.1
Gm10610
predicted gene 10610
chr6_-_29165003 0.415 ENSMUST00000007993.9
Rbm28
RNA binding motif protein 28
chr18_+_32067729 0.414 ENSMUST00000025243.3
Iws1
IWS1 homolog (S. cerevisiae)
chr14_-_52237791 0.406 ENSMUST00000149975.1
Chd8
chromodomain helicase DNA binding protein 8

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 20.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
1.5 6.0 GO:1900623 positive regulation of keratinocyte proliferation(GO:0010838) regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
1.2 3.5 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
1.0 4.0 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
1.0 3.0 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.8 2.3 GO:0007525 somatic muscle development(GO:0007525)
0.7 2.2 GO:1902071 positive regulation of cellular response to hypoxia(GO:1900039) regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.7 13.3 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.6 2.4 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.6 3.4 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.6 2.8 GO:0060467 negative regulation of fertilization(GO:0060467)
0.5 2.3 GO:0007386 compartment pattern specification(GO:0007386)
0.5 2.8 GO:0072318 clathrin coat disassembly(GO:0072318)
0.5 2.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.4 2.7 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) phosphate ion transmembrane transport(GO:0035435) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.4 3.8 GO:0071420 cellular response to histamine(GO:0071420)
0.4 2.0 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.4 2.2 GO:0045919 complement activation, alternative pathway(GO:0006957) positive regulation of cytolysis(GO:0045919)
0.4 1.5 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.4 1.5 GO:0044330 canonical Wnt signaling pathway involved in positive regulation of wound healing(GO:0044330) lactic acid secretion(GO:0046722) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.4 1.4 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.3 1.0 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.3 1.3 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.3 2.0 GO:0007258 JUN phosphorylation(GO:0007258)
0.3 1.8 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.3 1.6 GO:0032796 uropod organization(GO:0032796)
0.3 1.8 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.3 1.0 GO:0072592 oxygen metabolic process(GO:0072592)
0.3 3.0 GO:0006012 galactose metabolic process(GO:0006012)
0.3 1.0 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.2 1.7 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.2 1.3 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.2 1.7 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.2 0.6 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.2 1.0 GO:0032329 serine transport(GO:0032329)
0.2 6.0 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.2 0.6 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.2 0.6 GO:1990927 negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927)
0.2 8.5 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.2 0.5 GO:0043323 positive regulation of natural killer cell degranulation(GO:0043323)
0.2 0.7 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.2 1.1 GO:0098734 protein depalmitoylation(GO:0002084) negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005) macromolecule depalmitoylation(GO:0098734)
0.2 0.4 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.2 0.5 GO:1902277 negative regulation of pancreatic amylase secretion(GO:1902277)
0.2 0.7 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.2 1.2 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.2 0.9 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.2 0.5 GO:1900127 positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.2 2.5 GO:0006828 manganese ion transport(GO:0006828)
0.2 1.0 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.2 0.6 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.2 0.9 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.2 0.5 GO:0035799 ureter maturation(GO:0035799) cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536)
0.2 0.3 GO:0072501 cellular divalent inorganic anion homeostasis(GO:0072501)
0.1 0.9 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 0.6 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.1 0.6 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.1 1.4 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 0.5 GO:0036216 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.1 3.6 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1 0.6 GO:0072530 purine-containing compound transmembrane transport(GO:0072530)
0.1 0.5 GO:0090365 regulation of mRNA modification(GO:0090365)
0.1 0.5 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.4 GO:0021972 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.1 1.6 GO:0034390 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.1 1.0 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.1 0.3 GO:0051030 snRNA transport(GO:0051030)
0.1 1.0 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 3.2 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 0.4 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.3 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.9 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.1 0.4 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 3.5 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 1.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 5.0 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1 1.2 GO:0048194 Golgi vesicle budding(GO:0048194)
0.1 1.9 GO:0006625 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.1 1.3 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.1 0.6 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 0.8 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.1 3.0 GO:0006270 DNA replication initiation(GO:0006270)
0.1 0.4 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.5 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 1.6 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.1 0.9 GO:0006706 steroid catabolic process(GO:0006706)
0.1 0.3 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 0.7 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 0.2 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 0.5 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.4 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.1 0.6 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.1 4.3 GO:0060349 bone morphogenesis(GO:0060349)
0.1 5.6 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 0.5 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.9 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 0.3 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.5 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.1 0.3 GO:0019695 choline metabolic process(GO:0019695)
0.1 0.4 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1 0.1 GO:0071726 response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
0.0 0.9 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.8 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 1.1 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.1 GO:0071873 response to norepinephrine(GO:0071873)
0.0 0.2 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 1.3 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.5 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.9 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.8 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 1.6 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.0 0.6 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.0 0.4 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.0 0.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.2 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 1.2 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.8 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.4 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 2.1 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.5 GO:0032402 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 1.4 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 0.2 GO:0030035 microspike assembly(GO:0030035)
0.0 1.5 GO:0007416 synapse assembly(GO:0007416)
0.0 0.8 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.7 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.8 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.5 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.1 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 2.3 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.5 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.1 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 1.5 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 1.8 GO:0001666 response to hypoxia(GO:0001666)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.4 GO:0044316 cone cell pedicle(GO:0044316)
0.4 3.5 GO:0000805 X chromosome(GO:0000805)
0.3 1.3 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.3 3.4 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.3 3.8 GO:1902711 GABA-A receptor complex(GO:1902711)
0.2 4.0 GO:0005640 nuclear outer membrane(GO:0005640)
0.2 0.7 GO:0042642 actomyosin, myosin complex part(GO:0042642)
0.2 1.7 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.2 0.6 GO:0042584 chromaffin granule membrane(GO:0042584)
0.2 2.4 GO:0070852 cell body fiber(GO:0070852)
0.2 0.9 GO:0070826 paraferritin complex(GO:0070826)
0.2 1.6 GO:0008290 F-actin capping protein complex(GO:0008290)
0.2 0.5 GO:0000799 nuclear condensin complex(GO:0000799)
0.2 1.5 GO:0071439 clathrin complex(GO:0071439)
0.1 1.6 GO:0032426 stereocilium tip(GO:0032426)
0.1 0.5 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 0.6 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 1.7 GO:0043196 varicosity(GO:0043196)
0.1 3.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 0.9 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 0.9 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.1 0.5 GO:1990246 uniplex complex(GO:1990246)
0.1 1.1 GO:0005687 U4 snRNP(GO:0005687)
0.1 0.9 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 1.0 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.4 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.4 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.1 2.6 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 2.7 GO:0043034 costamere(GO:0043034)
0.1 1.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.6 GO:0032009 early phagosome(GO:0032009)
0.1 0.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 2.5 GO:0005801 cis-Golgi network(GO:0005801)
0.0 3.1 GO:0070469 respiratory chain(GO:0070469)
0.0 3.7 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 2.2 GO:0044295 axonal growth cone(GO:0044295)
0.0 4.1 GO:0042641 actomyosin(GO:0042641)
0.0 0.3 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.9 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 2.8 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.5 GO:0005869 dynactin complex(GO:0005869)
0.0 1.6 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 11.2 GO:0014069 postsynaptic density(GO:0014069)
0.0 1.4 GO:0016592 mediator complex(GO:0016592)
0.0 0.6 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.3 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.2 GO:0098644 complex of collagen trimers(GO:0098644)
0.0 1.1 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.4 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 2.1 GO:0072562 blood microparticle(GO:0072562)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.5 GO:0045120 pronucleus(GO:0045120)
0.0 0.1 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.0 0.3 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 4.5 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.5 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.9 GO:0005814 centriole(GO:0005814)
0.0 2.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 6.5 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.7 GO:0097223 sperm part(GO:0097223)
0.0 2.3 GO:0001650 fibrillar center(GO:0001650)
0.0 0.4 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.7 GO:0044452 nucleolar part(GO:0044452)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 6.0 GO:0050501 hyaluronan synthase activity(GO:0050501)
1.7 10.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
1.0 3.0 GO:0004335 galactokinase activity(GO:0004335)
0.9 2.7 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.8 2.4 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.7 2.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.6 2.2 GO:0001851 complement component C3b binding(GO:0001851)
0.5 2.0 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.4 2.5 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.3 1.7 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.3 4.0 GO:0043495 protein anchor(GO:0043495)
0.3 2.3 GO:0070324 thyroid hormone binding(GO:0070324)
0.3 1.0 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.2 1.6 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 1.7 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.2 3.8 GO:0004890 GABA-A receptor activity(GO:0004890)
0.2 2.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.2 1.0 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 5.0 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.2 2.8 GO:0045499 chemorepellent activity(GO:0045499)
0.2 0.9 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.2 0.9 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 1.6 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.6 GO:0051525 NFAT protein binding(GO:0051525)
0.1 4.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 1.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 5.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.7 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.5 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.1 0.3 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.1 22.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 1.1 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.6 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 1.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 1.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 0.6 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 3.2 GO:0005112 Notch binding(GO:0005112)
0.1 5.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 2.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 1.0 GO:0005522 profilin binding(GO:0005522)
0.1 0.6 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.1 2.4 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 1.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.8 GO:0050692 DBD domain binding(GO:0050692)
0.1 1.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.4 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.8 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 1.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.5 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.8 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 1.2 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 2.3 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 1.0 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.3 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 3.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 2.1 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.9 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.9 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.3 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 1.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.7 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 1.4 GO:0030552 cAMP binding(GO:0030552)
0.0 0.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.7 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.4 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 2.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 2.1 GO:0005518 collagen binding(GO:0005518)
0.0 0.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.6 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.3 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.5 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.7 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.6 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.9 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 3.5 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.8 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.5 GO:0043274 phospholipase binding(GO:0043274)
0.0 2.6 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)
0.0 0.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
0.0 0.1 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.0 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.6 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.2 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.5 GO:0030507 spectrin binding(GO:0030507)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 10.5 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 2.9 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 4.0 PID_CD40_PATHWAY CD40/CD40L signaling
0.1 2.7 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.1 2.0 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.8 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.1 2.7 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.1 2.3 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 2.0 NABA_COLLAGENS Genes encoding collagen proteins
0.0 6.4 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.7 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 1.0 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.5 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 0.9 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.0 2.8 PID_CDC42_PATHWAY CDC42 signaling events
0.0 0.6 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.9 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.5 PID_IL27_PATHWAY IL27-mediated signaling events
0.0 0.8 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.9 ST_FAS_SIGNALING_PATHWAY Fas Signaling Pathway
0.0 0.5 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.0 0.5 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.4 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 0.8 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 0.6 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
0.4 2.2 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.4 2.5 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.4 6.0 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.3 4.4 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 3.8 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.2 1.3 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.2 2.1 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 1.6 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 2.5 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 2.1 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 2.8 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 1.0 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.1 1.7 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.1 0.8 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.7 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 2.8 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 1.0 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 1.6 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.1 1.4 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.0 2.0 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 2.4 REACTOME_AMYLOIDS Genes involved in Amyloids
0.0 0.5 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.0 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.5 REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 2.5 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 0.7 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.9 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.3 REACTOME_ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.2 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 1.0 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.6 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.0 2.5 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.1 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.1 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1