Motif ID: Nfe2l1_Mafg

Z-value: 1.127

Transcription factors associated with Nfe2l1_Mafg:

Gene SymbolEntrez IDGene Name
Mafg ENSMUSG00000051510.7 Mafg
Mafg ENSMUSG00000053906.4 Mafg
Nfe2l1 ENSMUSG00000038615.11 Nfe2l1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mafgmm10_v2_chr11_-_120633594_120633605-0.653.9e-06Click!
Nfe2l1mm10_v2_chr11_-_96829904_96829955-0.163.2e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Nfe2l1_Mafg

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_23248264 31.953 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr7_-_137314394 9.918 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
Ebf3



early B cell factor 3



chr17_+_93199348 7.830 ENSMUST00000064775.6
Adcyap1
adenylate cyclase activating polypeptide 1
chr17_+_43952999 5.721 ENSMUST00000177857.1
Rcan2
regulator of calcineurin 2
chr3_+_85915722 4.740 ENSMUST00000054148.7
Gm9790
predicted gene 9790
chr8_+_31091593 4.460 ENSMUST00000161713.1
Dusp26
dual specificity phosphatase 26 (putative)
chr9_-_79977782 4.435 ENSMUST00000093811.4
Filip1
filamin A interacting protein 1
chr14_+_74640840 4.086 ENSMUST00000036653.3
Htr2a
5-hydroxytryptamine (serotonin) receptor 2A
chr2_-_112480817 3.996 ENSMUST00000099589.2
Chrm5
cholinergic receptor, muscarinic 5
chr4_+_101507855 3.719 ENSMUST00000038207.5
Dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr18_-_62741387 3.580 ENSMUST00000097557.3
Spink13
serine peptidase inhibitor, Kazal type 13
chr12_-_10900296 3.429 ENSMUST00000085735.2
Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chr17_-_48432723 3.095 ENSMUST00000046549.3
Apobec2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr17_+_78491549 3.046 ENSMUST00000079363.4
Gm10093
predicted pseudogene 10093
chr11_+_44617310 2.933 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
Ebf1


early B cell factor 1


chr18_-_47333311 2.891 ENSMUST00000126684.1
ENSMUST00000156422.1
Sema6a

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A

chr4_-_63403330 2.851 ENSMUST00000035724.4
Akna
AT-hook transcription factor
chr7_-_74554474 2.755 ENSMUST00000134539.1
ENSMUST00000026897.7
ENSMUST00000098371.2
Slco3a1


solute carrier organic anion transporter family, member 3a1


chr15_+_16778101 2.594 ENSMUST00000026432.6
Cdh9
cadherin 9
chrX_-_141874870 2.538 ENSMUST00000182079.1
Gm15294
predicted gene 15294
chr10_+_31248140 2.432 ENSMUST00000050717.8
Gm5422
predicted pseudogene 5422
chr10_+_19356558 2.407 ENSMUST00000053225.5
Olig3
oligodendrocyte transcription factor 3
chr15_+_101224207 2.378 ENSMUST00000000543.4
Grasp
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
chr12_+_38783503 2.374 ENSMUST00000159334.1
Etv1
ets variant gene 1
chr3_-_33082004 2.300 ENSMUST00000108225.3
Pex5l
peroxisomal biogenesis factor 5-like
chr7_+_51621830 2.223 ENSMUST00000032710.5
Slc17a6
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
chr14_+_12189943 2.157 ENSMUST00000119888.1
Ptprg
protein tyrosine phosphatase, receptor type, G
chr1_-_183147461 2.130 ENSMUST00000171366.1
Disp1
dispatched homolog 1 (Drosophila)
chr2_-_121271403 2.068 ENSMUST00000110648.1
Trp53bp1
transformation related protein 53 binding protein 1
chr12_-_54986363 2.044 ENSMUST00000173433.1
ENSMUST00000173803.1
Baz1a
Gm20403
bromodomain adjacent to zinc finger domain 1A
predicted gene 20403
chr5_+_128601106 2.025 ENSMUST00000117102.2
Fzd10
frizzled homolog 10 (Drosophila)
chrX_-_49788204 1.988 ENSMUST00000114893.1
Igsf1
immunoglobulin superfamily, member 1
chr12_+_38783455 1.971 ENSMUST00000161980.1
ENSMUST00000160701.1
Etv1

ets variant gene 1

chr2_-_121271341 1.971 ENSMUST00000110647.1
Trp53bp1
transformation related protein 53 binding protein 1
chr12_+_55598917 1.826 ENSMUST00000051857.3
Insm2
insulinoma-associated 2
chr3_-_92083132 1.790 ENSMUST00000058150.6
Lor
loricrin
chr11_-_66525795 1.773 ENSMUST00000123454.1
Shisa6
shisa homolog 6 (Xenopus laevis)
chr2_+_130277157 1.740 ENSMUST00000028890.8
ENSMUST00000159373.1
Nop56

NOP56 ribonucleoprotein

chr11_-_75796048 1.674 ENSMUST00000021209.7
Doc2b
double C2, beta
chr7_-_16917184 1.651 ENSMUST00000173139.1
Calm3
calmodulin 3
chr1_-_45890078 1.637 ENSMUST00000183590.1
Gm5269
predicted gene 5269
chr7_-_74554726 1.566 ENSMUST00000107453.1
Slco3a1
solute carrier organic anion transporter family, member 3a1
chr9_-_66795469 1.558 ENSMUST00000034934.8
Aph1b
anterior pharynx defective 1b homolog (C. elegans)
chr18_+_35771574 1.534 ENSMUST00000167406.1
Ube2d2a
ubiquitin-conjugating enzyme E2D 2A
chr2_-_121271315 1.528 ENSMUST00000131245.1
Trp53bp1
transformation related protein 53 binding protein 1
chr13_-_55528511 1.520 ENSMUST00000047877.4
Dok3
docking protein 3
chr11_+_72607221 1.470 ENSMUST00000021148.6
ENSMUST00000138247.1
Ube2g1

ubiquitin-conjugating enzyme E2G 1

chr19_+_56722372 1.416 ENSMUST00000038949.4
Adrb1
adrenergic receptor, beta 1
chr6_+_88724828 1.407 ENSMUST00000089449.2
Mgll
monoglyceride lipase
chr10_-_13868779 1.386 ENSMUST00000105534.3
Aig1
androgen-induced 1
chr3_+_135438722 1.354 ENSMUST00000166033.1
Ube2d3
ubiquitin-conjugating enzyme E2D 3
chr14_-_76237353 1.348 ENSMUST00000095471.4
Rps2-ps6
ribosomal protein S2, pseudogene 6
chr6_+_88724667 1.347 ENSMUST00000163271.1
Mgll
monoglyceride lipase
chr9_-_66795331 1.338 ENSMUST00000113730.2
Aph1b
anterior pharynx defective 1b homolog (C. elegans)
chr6_+_15196949 1.302 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
Foxp2



forkhead box P2



chr10_-_64090265 1.276 ENSMUST00000105439.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr15_+_31276491 1.269 ENSMUST00000068987.5
Fam136b-ps
family with sequence similarity 136, member B, pseudogene
chr3_+_103058302 1.238 ENSMUST00000029445.6
Nras
neuroblastoma ras oncogene
chr8_+_123332676 1.230 ENSMUST00000010298.6
Spire2
spire homolog 2 (Drosophila)
chrX_+_134404780 1.227 ENSMUST00000113224.2
ENSMUST00000113226.1
Drp2

dystrophin related protein 2

chr1_-_65051119 1.207 ENSMUST00000161960.1
ENSMUST00000087359.5
Cryge

crystallin, gamma E

chr4_-_117125618 1.184 ENSMUST00000183310.1
Btbd19
BTB (POZ) domain containing 19
chr7_-_116038734 1.176 ENSMUST00000166877.1
Sox6
SRY-box containing gene 6
chr15_+_12321472 1.154 ENSMUST00000059680.5
Golph3
golgi phosphoprotein 3
chr3_+_135438280 1.130 ENSMUST00000106291.3
Ube2d3
ubiquitin-conjugating enzyme E2D 3
chr6_-_99044414 1.111 ENSMUST00000177507.1
ENSMUST00000123992.1
Foxp1

forkhead box P1

chr11_-_120348091 1.100 ENSMUST00000106215.4
Actg1
actin, gamma, cytoplasmic 1
chr6_-_72361396 1.079 ENSMUST00000130064.1
Rnf181
ring finger protein 181
chr19_-_60874526 1.069 ENSMUST00000025961.6
Prdx3
peroxiredoxin 3
chr18_+_6332587 1.055 ENSMUST00000097682.2
Rpl27-ps3
ribosomal protein L27, pseudogene 3
chr17_+_35821675 1.040 ENSMUST00000003635.6
Ier3
immediate early response 3
chr5_-_138187177 1.037 ENSMUST00000110937.1
ENSMUST00000139276.1
ENSMUST00000048698.7
ENSMUST00000123415.1
Taf6



TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor



chr17_+_70929006 1.031 ENSMUST00000092011.6
Gm16519
predicted gene, 16519
chr5_+_30913398 1.020 ENSMUST00000031055.5
Emilin1
elastin microfibril interfacer 1
chr10_-_95673451 1.010 ENSMUST00000099328.1
Anapc15-ps
anaphase prompoting complex C subunit 15, pseudogene
chr12_+_55398775 1.006 ENSMUST00000021412.8
Psma6
proteasome (prosome, macropain) subunit, alpha type 6
chr13_-_102958084 1.002 ENSMUST00000099202.3
ENSMUST00000172264.1
Mast4

microtubule associated serine/threonine kinase family member 4

chr2_-_25272380 0.999 ENSMUST00000028342.6
Ssna1
Sjogren's syndrome nuclear autoantigen 1
chr8_-_125492710 0.996 ENSMUST00000108775.1
Sipa1l2
signal-induced proliferation-associated 1 like 2
chr4_-_63662910 0.973 ENSMUST00000184252.1
Gm11214
predicted gene 11214
chr7_+_29307924 0.952 ENSMUST00000108230.1
ENSMUST00000065181.5
Dpf1

D4, zinc and double PHD fingers family 1

chr11_+_23020464 0.939 ENSMUST00000094363.3
ENSMUST00000151877.1
Fam161a

family with sequence similarity 161, member A

chr8_+_54077532 0.935 ENSMUST00000033919.4
Vegfc
vascular endothelial growth factor C
chr7_-_84679346 0.927 ENSMUST00000069537.2
ENSMUST00000178385.1
Zfand6

zinc finger, AN1-type domain 6

chr4_-_33248500 0.925 ENSMUST00000049357.9
Pnrc1
proline-rich nuclear receptor coactivator 1
chrX_+_36795642 0.923 ENSMUST00000016463.3
Slc25a5
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5
chrM_+_7005 0.880 ENSMUST00000082405.1
mt-Co2
mitochondrially encoded cytochrome c oxidase II
chr4_-_43454582 0.867 ENSMUST00000107925.1
Cd72
CD72 antigen
chr10_+_52022502 0.847 ENSMUST00000163017.1
ENSMUST00000058347.4
Vgll2

vestigial like 2 homolog (Drosophila)

chr9_-_50344981 0.815 ENSMUST00000076364.4
Rpl10-ps3
ribosomal protein L10, pseudogene 3
chr2_-_65022740 0.796 ENSMUST00000028252.7
Grb14
growth factor receptor bound protein 14
chr8_+_94984399 0.796 ENSMUST00000093271.6
Gpr56
G protein-coupled receptor 56
chr2_-_120609319 0.787 ENSMUST00000102497.3
Lrrc57
leucine rich repeat containing 57
chr9_-_106887000 0.784 ENSMUST00000055843.7
Rbm15b
RNA binding motif protein 15B
chr4_-_43454563 0.781 ENSMUST00000107926.1
Cd72
CD72 antigen
chr17_-_70998010 0.781 ENSMUST00000024846.6
Myl12a
myosin, light chain 12A, regulatory, non-sarcomeric
chr17_-_63863791 0.763 ENSMUST00000050753.3
A930002H24Rik
RIKEN cDNA A930002H24 gene
chr2_-_120609283 0.752 ENSMUST00000102496.1
Lrrc57
leucine rich repeat containing 57
chr10_+_80930071 0.749 ENSMUST00000015456.8
Gadd45b
growth arrest and DNA-damage-inducible 45 beta
chr14_-_57826128 0.746 ENSMUST00000022536.2
Ska3
spindle and kinetochore associated complex subunit 3
chr7_+_101896817 0.745 ENSMUST00000143835.1
Anapc15
anaphase prompoting complex C subunit 15
chr4_-_116708312 0.743 ENSMUST00000030453.4
Mmachc
methylmalonic aciduria cblC type, with homocystinuria
chr12_+_17348422 0.742 ENSMUST00000046011.10
Nol10
nucleolar protein 10
chr17_-_34603675 0.731 ENSMUST00000015622.7
Rnf5
ring finger protein 5
chr13_-_58215615 0.731 ENSMUST00000058735.5
ENSMUST00000076454.6
Ubqln1

ubiquilin 1

chr15_+_44196135 0.711 ENSMUST00000038856.6
ENSMUST00000110289.3
Trhr

thyrotropin releasing hormone receptor

chr9_+_108508005 0.710 ENSMUST00000006838.8
ENSMUST00000134939.1
Qars

glutaminyl-tRNA synthetase

chr19_+_12846773 0.700 ENSMUST00000164001.1
Gm5244
predicted pseudogene 5244
chr5_-_65391408 0.689 ENSMUST00000057885.6
Rpl9
ribosomal protein L9
chr12_-_69372443 0.676 ENSMUST00000053451.1
Gm9887
predicted gene 9887
chr2_+_180171485 0.672 ENSMUST00000061437.4
Adrm1
adhesion regulating molecule 1
chr5_-_65391380 0.660 ENSMUST00000120094.1
ENSMUST00000118543.1
ENSMUST00000127874.1
Rpl9


ribosomal protein L9


chr11_-_116853083 0.659 ENSMUST00000092404.6
Srsf2
serine/arginine-rich splicing factor 2
chr11_+_101087277 0.657 ENSMUST00000107302.1
ENSMUST00000107303.3
ENSMUST00000017945.8
ENSMUST00000149597.1
Mlx



MAX-like protein X



chr1_+_127774164 0.656 ENSMUST00000027587.8
ENSMUST00000112570.1
Ccnt2

cyclin T2

chr11_-_52000432 0.650 ENSMUST00000020657.6
Ube2b
ubiquitin-conjugating enzyme E2B
chr7_-_28050028 0.646 ENSMUST00000032824.9
Psmc4
proteasome (prosome, macropain) 26S subunit, ATPase, 4
chr15_-_81104999 0.640 ENSMUST00000109579.2
Mkl1
MKL (megakaryoblastic leukemia)/myocardin-like 1
chr5_+_123907175 0.630 ENSMUST00000023869.8
Denr
density-regulated protein
chr13_-_68999518 0.606 ENSMUST00000022013.7
Adcy2
adenylate cyclase 2
chr10_-_84533884 0.604 ENSMUST00000053871.3
Ckap4
cytoskeleton-associated protein 4
chr10_+_13008442 0.603 ENSMUST00000105139.3
Sf3b5
splicing factor 3b, subunit 5
chr19_-_7217549 0.578 ENSMUST00000039758.4
Cox8a
cytochrome c oxidase subunit VIIIa
chr2_-_165283599 0.571 ENSMUST00000155289.1
Slc35c2
solute carrier family 35, member C2
chrX_-_75130996 0.567 ENSMUST00000033775.2
Mpp1
membrane protein, palmitoylated
chr11_-_52000748 0.566 ENSMUST00000109086.1
Ube2b
ubiquitin-conjugating enzyme E2B
chr4_-_43454600 0.559 ENSMUST00000098105.3
ENSMUST00000098104.3
ENSMUST00000030179.4
Cd72


CD72 antigen


chr2_-_120609500 0.550 ENSMUST00000133612.1
ENSMUST00000102498.1
ENSMUST00000102499.1
Lrrc57


leucine rich repeat containing 57


chr4_+_131921771 0.549 ENSMUST00000094666.3
Tmem200b
transmembrane protein 200B
chrX_-_139714481 0.537 ENSMUST00000183728.1
Gm15013
predicted gene 15013
chrX_+_71556874 0.534 ENSMUST00000123100.1
Hmgb3
high mobility group box 3
chr11_+_48800357 0.531 ENSMUST00000020640.7
Gnb2l1
guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1
chr13_-_32338565 0.505 ENSMUST00000041859.7
Gmds
GDP-mannose 4, 6-dehydratase
chr9_+_53771499 0.501 ENSMUST00000048670.8
Slc35f2
solute carrier family 35, member F2
chr6_-_128438673 0.501 ENSMUST00000032508.4
Fkbp4
FK506 binding protein 4
chr9_+_48450327 0.497 ENSMUST00000165252.1
Gm5616
predicted gene 5616
chr11_-_50325599 0.495 ENSMUST00000179865.1
ENSMUST00000020637.8
Canx

calnexin

chr2_-_18998126 0.493 ENSMUST00000006912.5
Pip4k2a
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr17_+_8182247 0.490 ENSMUST00000161898.1
Fgfr1op
Fgfr1 oncogene partner
chr18_-_80151467 0.485 ENSMUST00000066743.9
Adnp2
ADNP homeobox 2
chr2_-_106002008 0.481 ENSMUST00000155811.1
Dnajc24
DnaJ (Hsp40) homolog, subfamily C, member 24
chr9_-_22130598 0.477 ENSMUST00000115315.2
Acp5
acid phosphatase 5, tartrate resistant
chr17_-_55915870 0.469 ENSMUST00000074828.4
Rpl21-ps6
ribosomal protein L21, pseudogene 6
chr14_+_57826210 0.464 ENSMUST00000022538.3
Mrp63
mitochondrial ribosomal protein 63
chr16_-_89508313 0.463 ENSMUST00000056118.2
Krtap7-1
keratin associated protein 7-1
chr12_+_69372112 0.462 ENSMUST00000050063.7
Arf6
ADP-ribosylation factor 6
chr5_-_51553896 0.461 ENSMUST00000132734.1
Ppargc1a
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
chr17_-_46282991 0.453 ENSMUST00000180283.1
ENSMUST00000012440.6
ENSMUST00000164342.2
Tjap1


tight junction associated protein 1


chrX_-_155216338 0.452 ENSMUST00000112551.3
Sat1
spermidine/spermine N1-acetyl transferase 1
chr11_-_69921057 0.435 ENSMUST00000108609.1
ENSMUST00000108608.1
ENSMUST00000164359.1
Eif5a


eukaryotic translation initiation factor 5A


chr12_-_56535047 0.428 ENSMUST00000178477.2
Nkx2-1
NK2 homeobox 1
chr18_-_10030017 0.428 ENSMUST00000116669.1
ENSMUST00000092096.6
Usp14

ubiquitin specific peptidase 14

chr15_+_8109313 0.421 ENSMUST00000163765.1
Nup155
nucleoporin 155
chrX_-_70477170 0.413 ENSMUST00000101506.3
ENSMUST00000114630.2
BC023829

cDNA sequence BC023829

chr14_+_29978337 0.413 ENSMUST00000016115.4
Actr8
ARP8 actin-related protein 8
chr6_-_86669136 0.410 ENSMUST00000001184.7
Mxd1
MAX dimerization protein 1
chr4_-_129640691 0.394 ENSMUST00000084264.5
Txlna
taxilin alpha
chr17_-_27907706 0.392 ENSMUST00000025057.4
Taf11
TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chrX_-_155216444 0.384 ENSMUST00000026318.8
Sat1
spermidine/spermine N1-acetyl transferase 1
chr13_-_107890059 0.380 ENSMUST00000105097.2
Zswim6
zinc finger SWIM-type containing 6
chr16_-_15863347 0.377 ENSMUST00000023351.4
ENSMUST00000117136.1
Mzt2

mitotic spindle organizing protein 2

chr11_+_51619731 0.375 ENSMUST00000127405.1
Nhp2
NHP2 ribonucleoprotein
chr14_+_52279132 0.371 ENSMUST00000022766.6
Tox4
TOX high mobility group box family member 4
chr5_-_24842579 0.368 ENSMUST00000030787.8
Rheb
Ras homolog enriched in brain
chr8_-_40511663 0.366 ENSMUST00000135269.1
ENSMUST00000034012.3
Cnot7

CCR4-NOT transcription complex, subunit 7

chr11_-_83649349 0.360 ENSMUST00000001008.5
Ccl3
chemokine (C-C motif) ligand 3
chr2_+_119742306 0.350 ENSMUST00000028758.7
Itpka
inositol 1,4,5-trisphosphate 3-kinase A
chr9_+_59589288 0.344 ENSMUST00000121266.1
ENSMUST00000118164.1
Celf6

CUGBP, Elav-like family member 6

chr3_+_130068390 0.335 ENSMUST00000076703.6
Gm9396
predicted gene 9396
chr11_-_116274102 0.333 ENSMUST00000106425.3
Srp68
signal recognition particle 68
chr14_+_11227511 0.330 ENSMUST00000080237.3
Rpl21-ps4
ribosomal protein L21, pseudogene 4
chr4_-_129641060 0.319 ENSMUST00000046425.9
ENSMUST00000133803.1
Txlna

taxilin alpha

chr11_-_116274197 0.314 ENSMUST00000021133.9
Srp68
signal recognition particle 68
chr8_-_124021008 0.313 ENSMUST00000093039.5
Taf5l
TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
chr3_+_88616133 0.309 ENSMUST00000176500.1
ENSMUST00000177498.1
Arhgef2

rho/rac guanine nucleotide exchange factor (GEF) 2

chr7_-_80340214 0.307 ENSMUST00000127997.1
ENSMUST00000032748.8
Unc45a

unc-45 homolog A (C. elegans)

chr18_-_15063560 0.303 ENSMUST00000168989.1
Kctd1
potassium channel tetramerisation domain containing 1
chr6_-_24528013 0.303 ENSMUST00000023851.5
Ndufa5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr2_-_165884636 0.296 ENSMUST00000177633.1
ENSMUST00000018050.7
ENSMUST00000088113.4
Zmynd8


zinc finger, MYND-type containing 8


chr12_-_56345862 0.295 ENSMUST00000021416.7
Mbip
MAP3K12 binding inhibitory protein 1
chr3_-_59262825 0.294 ENSMUST00000050360.7
P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr14_-_79481268 0.291 ENSMUST00000022601.5
Wbp4
WW domain binding protein 4
chr10_-_84533968 0.289 ENSMUST00000167671.1
Ckap4
cytoskeleton-associated protein 4
chr5_-_136198908 0.282 ENSMUST00000149151.1
ENSMUST00000151786.1
Prkrip1

Prkr interacting protein 1 (IL11 inducible)

chr11_-_103208542 0.279 ENSMUST00000021323.4
ENSMUST00000107026.2
1700023F06Rik

RIKEN cDNA 1700023F06 gene

chr1_-_55088024 0.278 ENSMUST00000027123.8
Hspd1
heat shock protein 1 (chaperonin)
chr16_+_58727910 0.276 ENSMUST00000023426.5
ENSMUST00000162057.1
ENSMUST00000162191.1
Cldn25


claudin 25


chr7_-_103741322 0.274 ENSMUST00000051346.2
Olfr629
olfactory receptor 629
chr2_+_151494274 0.263 ENSMUST00000028949.9
ENSMUST00000103160.4
Nsfl1c

NSFL1 (p97) cofactor (p47)

chr10_-_127070254 0.257 ENSMUST00000060991.4
Tspan31
tetraspanin 31
chr4_+_127021311 0.254 ENSMUST00000030623.7
Sfpq
splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)
chr1_-_191183244 0.254 ENSMUST00000027941.8
Atf3
activating transcription factor 3
chr13_+_53525703 0.251 ENSMUST00000081132.4
Gm5449
predicted pseudogene 5449
chr1_-_132367879 0.249 ENSMUST00000142609.1
Tmcc2
transmembrane and coiled-coil domains 2
chr2_+_151494182 0.244 ENSMUST00000089140.6
Nsfl1c
NSFL1 (p97) cofactor (p47)
chr12_+_84970897 0.244 ENSMUST00000021669.8
ENSMUST00000171040.1
Fcf1

FCF1 small subunit (SSU) processome component homolog (S. cerevisiae)

chr18_-_43477764 0.239 ENSMUST00000057110.9
Eif3j2
eukaryotic translation initiation factor 3, subunit J2
chr7_+_127573529 0.218 ENSMUST00000121004.1
Phkg2
phosphorylase kinase, gamma 2 (testis)
chr6_-_83121385 0.213 ENSMUST00000146328.1
ENSMUST00000113936.3
ENSMUST00000032111.4
Wbp1


WW domain binding protein 1


chr8_+_94532990 0.211 ENSMUST00000048653.2
ENSMUST00000109537.1
Cpne2

copine II


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.3 32.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
2.6 7.8 GO:0071649 negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865) regulation of chemokine (C-C motif) ligand 5 production(GO:0071649) positive regulation of somatostatin secretion(GO:0090274)
1.5 4.5 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
1.0 3.1 GO:0016554 cytidine to uridine editing(GO:0016554)
1.0 4.1 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.8 4.0 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.7 3.6 GO:0060467 negative regulation of fertilization(GO:0060467)
0.6 3.7 GO:0072318 clathrin coat disassembly(GO:0072318)
0.5 2.4 GO:0097476 spinal cord motor neuron migration(GO:0097476)
0.5 1.4 GO:1900133 renin secretion into blood stream(GO:0002001) regulation of renin secretion into blood stream(GO:1900133)
0.4 1.2 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.4 1.2 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.4 4.3 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.4 2.8 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.3 4.3 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.3 2.3 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.3 4.6 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.3 5.7 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.3 2.0 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.3 0.8 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.3 0.8 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.3 2.0 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.2 1.0 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.2 2.2 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.2 0.7 GO:0034140 negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) aggrephagy(GO:0035973)
0.2 0.9 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.2 1.2 GO:0090164 asymmetric Golgi ribbon formation(GO:0090164)
0.2 0.7 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.2 0.7 GO:0019085 early viral transcription(GO:0019085)
0.2 1.1 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.2 3.0 GO:0007220 Notch receptor processing(GO:0007220)
0.2 1.8 GO:0031424 keratinization(GO:0031424)
0.2 2.1 GO:0060539 diaphragm development(GO:0060539)
0.2 1.2 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.2 0.6 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.7 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
0.1 0.6 GO:0015786 UDP-glucose transport(GO:0015786)
0.1 0.4 GO:0021759 globus pallidus development(GO:0021759)
0.1 0.4 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1 0.4 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.1 0.6 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 2.9 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 0.5 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.1 1.1 GO:0061470 interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619)
0.1 0.5 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.1 1.2 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.1 0.3 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.1 1.7 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.1 1.3 GO:0060013 righting reflex(GO:0060013)
0.1 6.2 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 0.3 GO:0002842 positive regulation of T cell mediated immune response to tumor cell(GO:0002842) protein import into mitochondrial intermembrane space(GO:0045041)
0.1 0.7 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 1.8 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 1.3 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.1 0.5 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 0.4 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.2 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 0.3 GO:1903984 regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1 0.4 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 0.3 GO:1903756 regulation of postsynaptic density protein 95 clustering(GO:1902897) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 1.7 GO:0000154 rRNA modification(GO:0000154)
0.1 0.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.5 GO:0034143 regulation of toll-like receptor 4 signaling pathway(GO:0034143)
0.1 0.5 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.1 0.5 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.1 0.2 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.7 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.6 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.3 GO:0051189 molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.2 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.9 GO:0006625 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.1 GO:0030210 heparin biosynthetic process(GO:0030210) Tie signaling pathway(GO:0048014)
0.0 0.6 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.4 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.3 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0 2.2 GO:1901998 toxin transport(GO:1901998)
0.0 0.5 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.2 GO:1904659 glucose transmembrane transport(GO:1904659)
0.0 0.5 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.4 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 1.0 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.2 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.3 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.0 1.0 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.3 GO:0006020 inositol metabolic process(GO:0006020)
0.0 2.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.4 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.2 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 1.4 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.4 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 1.0 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.5 GO:0007030 Golgi organization(GO:0007030)
0.0 0.2 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.7 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.0 0.5 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 1.3 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.9 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.5 GO:0034453 microtubule anchoring(GO:0034453)
0.0 1.1 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.7 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.1 GO:1904245 regulation of polynucleotide adenylyltransferase activity(GO:1904245)
0.0 0.3 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.4 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.3 GO:0022904 respiratory electron transport chain(GO:0022904)
0.0 2.0 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 1.7 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.0 0.3 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.7 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.7 GO:0043066 negative regulation of apoptotic process(GO:0043066)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.5 2.0 GO:0008623 CHRAC(GO:0008623)
0.4 3.0 GO:0070765 gamma-secretase complex(GO:0070765)
0.4 1.8 GO:0001533 cornified envelope(GO:0001533)
0.3 4.1 GO:0070852 cell body fiber(GO:0070852)
0.2 1.7 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.2 0.7 GO:0035061 interchromatin granule(GO:0035061)
0.2 2.8 GO:0043196 varicosity(GO:0043196)
0.2 1.2 GO:0033503 HULC complex(GO:0033503)
0.2 0.5 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.2 5.6 GO:0035861 site of double-strand break(GO:0035861)
0.2 1.9 GO:0005641 nuclear envelope lumen(GO:0005641)
0.2 0.9 GO:0071817 MMXD complex(GO:0071817)
0.1 1.4 GO:0012505 endomembrane system(GO:0012505)
0.1 1.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 1.0 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 2.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.4 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.1 0.3 GO:0042025 host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.1 0.3 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.1 0.4 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 1.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 0.6 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.1 0.7 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 1.4 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.1 0.7 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1 0.6 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 0.7 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 7.0 GO:0043195 terminal bouton(GO:0043195)
0.1 0.4 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.7 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.5 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.8 GO:0016460 myosin II complex(GO:0016460)
0.0 0.4 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.5 GO:0090543 Flemming body(GO:0090543)
0.0 3.0 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.7 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 1.0 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.8 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 1.0 GO:0071565 nBAF complex(GO:0071565)
0.0 3.1 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.1 GO:0043034 costamere(GO:0043034)
0.0 0.3 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.6 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.4 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.8 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.3 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.9 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 2.8 GO:0001650 fibrillar center(GO:0001650)
0.0 0.7 GO:0016235 aggresome(GO:0016235)
0.0 1.2 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.4 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.6 GO:0005801 cis-Golgi network(GO:0005801)
0.0 2.1 GO:0070062 extracellular exosome(GO:0070062)
0.0 0.9 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.5 GO:0097440 apical dendrite(GO:0097440)
0.0 0.2 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.7 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 5.1 GO:0005730 nucleolus(GO:0005730)
0.0 0.4 GO:0032420 stereocilium(GO:0032420)
0.0 0.5 GO:0044295 axonal growth cone(GO:0044295)
0.0 1.7 GO:0030426 growth cone(GO:0030426)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.5 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
1.4 4.1 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
1.3 4.0 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
1.0 5.7 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.9 5.6 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.8 3.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.6 4.3 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.5 7.8 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.5 1.4 GO:0051379 epinephrine binding(GO:0051379)
0.5 2.3 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.4 1.7 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.3 2.1 GO:0015197 peptide transporter activity(GO:0015197)
0.3 0.8 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.2 2.0 GO:0034711 inhibin binding(GO:0034711)
0.2 2.4 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.2 2.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 2.9 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.2 1.0 GO:0098634 protein binding involved in cell-matrix adhesion(GO:0098634)
0.2 34.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2 0.5 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 2.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 6.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 1.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.6 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 0.5 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 2.2 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.1 1.7 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.6 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 1.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 0.7 GO:0031419 cobalamin binding(GO:0031419)
0.1 1.0 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 0.5 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 0.9 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 2.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.7 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.7 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 3.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 2.4 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 1.1 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 1.5 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.4 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.6 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 0.5 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 0.7 GO:0019215 intermediate filament binding(GO:0019215)
0.1 0.2 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.1 0.6 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.3 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.4 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 5.6 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.3 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.7 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.5 GO:0031996 thioesterase binding(GO:0031996)
0.0 14.4 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 1.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.0 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.5 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.4 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.4 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.4 GO:0070628 proteasome binding(GO:0070628)
0.0 0.3 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.8 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.3 GO:0019843 rRNA binding(GO:0019843)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 1.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.5 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.7 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.3 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.9 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.7 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.8 GO:0035254 glutamate receptor binding(GO:0035254)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.9 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.1 5.1 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 4.3 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 1.2 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 2.5 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.1 0.9 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.1 2.0 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.3 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.0 1.4 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 2.2 PID_BCR_5PATHWAY BCR signaling pathway
0.0 0.6 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 0.8 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.7 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 0.5 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.0 1.1 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.7 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.5 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 0.7 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.0 1.8 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.7 PID_CXCR4_PATHWAY CXCR4-mediated signaling events
0.0 0.4 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.1 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
0.5 4.3 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.5 4.9 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.2 2.9 REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR Genes involved in Regulated proteolysis of p75NTR
0.2 7.8 REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS Genes involved in Glucagon-type ligand receptors
0.1 2.8 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 2.5 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 3.7 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 2.2 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.1 1.9 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 0.9 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 2.6 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.8 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.1 0.3 REACTOME_ADP_SIGNALLING_THROUGH_P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.1 0.8 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.1 2.0 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 0.6 REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.5 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.3 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 2.2 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 3.1 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 2.1 REACTOME_RNA_POL_II_PRE_TRANSCRIPTION_EVENTS Genes involved in RNA Polymerase II Pre-transcription Events
0.0 1.7 REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.7 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.4 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 1.1 REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.2 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.0 0.5 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.5 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.4 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.6 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 2.8 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.6 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.2 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.7 REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.9 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 0.9 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.4 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.0 0.3 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.3 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA