Motif ID: Klf15

Z-value: 1.297


Transcription factors associated with Klf15:

Gene SymbolEntrez IDGene Name
Klf15 ENSMUSG00000030087.5 Klf15

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Klf15mm10_v2_chr6_+_90465287_904653040.343.2e-02Click!


Activity profile for motif Klf15.

activity profile for motif Klf15


Sorted Z-values histogram for motif Klf15

Sorted Z-values for motif Klf15



Network of associatons between targets according to the STRING database.



First level regulatory network of Klf15

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_56971762 10.479 ENSMUST00000114415.3
Satb2
special AT-rich sequence binding protein 2
chr18_-_89769479 9.034 ENSMUST00000097495.3
Dok6
docking protein 6
chr11_+_50602072 6.711 ENSMUST00000040523.8
Adamts2
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2
chr1_-_56972437 5.993 ENSMUST00000042857.7
Satb2
special AT-rich sequence binding protein 2
chr3_+_118433797 5.966 ENSMUST00000180593.1
ENSMUST00000181926.1
ENSMUST00000181060.1
ENSMUST00000181310.1
Gm26871



predicted gene, 26871



chr11_+_69765970 5.207 ENSMUST00000108642.1
ENSMUST00000156932.1
Zbtb4

zinc finger and BTB domain containing 4

chr5_+_137288273 5.128 ENSMUST00000024099.4
ENSMUST00000085934.3
Ache

acetylcholinesterase

chr7_+_46396439 4.921 ENSMUST00000025202.6
Kcnc1
potassium voltage gated channel, Shaw-related subfamily, member 1
chr1_-_161034794 4.683 ENSMUST00000177003.1
ENSMUST00000162226.2
ENSMUST00000159250.2
Zbtb37


zinc finger and BTB domain containing 37


chr17_+_46297917 4.674 ENSMUST00000166617.1
ENSMUST00000170271.1
Dlk2

delta-like 2 homolog (Drosophila)

chr10_-_127666598 4.662 ENSMUST00000099157.3
Nab2
Ngfi-A binding protein 2
chr11_-_54068932 4.564 ENSMUST00000093109.4
ENSMUST00000018755.3
Pdlim4

PDZ and LIM domain 4

chr11_+_69765899 4.455 ENSMUST00000108640.1
ENSMUST00000108639.1
Zbtb4

zinc finger and BTB domain containing 4

chr10_-_127666673 4.072 ENSMUST00000026469.2
Nab2
Ngfi-A binding protein 2
chr19_+_5740885 3.876 ENSMUST00000081496.5
Ltbp3
latent transforming growth factor beta binding protein 3
chrX_-_136868537 3.835 ENSMUST00000058814.6
Rab9b
RAB9B, member RAS oncogene family
chr9_+_21927471 3.815 ENSMUST00000170304.1
ENSMUST00000006403.6
Ccdc159

coiled-coil domain containing 159

chr15_+_57694651 3.686 ENSMUST00000096430.4
Zhx2
zinc fingers and homeoboxes 2
chr18_-_66291770 3.615 ENSMUST00000130300.1
Ccbe1
collagen and calcium binding EGF domains 1
chr6_-_53068562 3.592 ENSMUST00000074541.5
Jazf1
JAZF zinc finger 1
chr18_-_31949571 3.564 ENSMUST00000064016.5
Gpr17
G protein-coupled receptor 17
chr3_+_156561950 3.530 ENSMUST00000041425.5
ENSMUST00000106065.1
Negr1

neuronal growth regulator 1

chr10_+_39732099 3.415 ENSMUST00000019986.6
Rev3l
REV3-like, catalytic subunit of DNA polymerase zeta RAD54 like (S. cerevisiae)
chr9_-_79718631 3.394 ENSMUST00000180083.1
Col12a1
collagen, type XII, alpha 1
chr9_+_45430293 3.390 ENSMUST00000034592.8
Dscaml1
Down syndrome cell adhesion molecule like 1
chr10_-_81430966 3.372 ENSMUST00000117966.1
Nfic
nuclear factor I/C
chr9_-_79718518 3.357 ENSMUST00000071750.6
Col12a1
collagen, type XII, alpha 1
chr4_-_88033328 3.314 ENSMUST00000078090.5
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr10_+_79716588 3.227 ENSMUST00000099513.1
ENSMUST00000020581.2
Hcn2

hyperpolarization-activated, cyclic nucleotide-gated K+ 2

chr7_+_97579868 3.203 ENSMUST00000042399.7
ENSMUST00000107153.1
Rsf1

remodeling and spacing factor 1

chr11_-_97573929 3.187 ENSMUST00000126287.1
ENSMUST00000107590.1
Srcin1

SRC kinase signaling inhibitor 1

chr6_-_39725193 3.184 ENSMUST00000101497.3
Braf
Braf transforming gene
chr2_+_4300462 3.156 ENSMUST00000175669.1
Frmd4a
FERM domain containing 4A
chr2_-_20968881 3.150 ENSMUST00000114594.1
Arhgap21
Rho GTPase activating protein 21
chr11_-_62731865 3.112 ENSMUST00000150336.1
Zfp287
zinc finger protein 287
chr12_+_81631369 3.048 ENSMUST00000036116.5
Ttc9
tetratricopeptide repeat domain 9
chr6_-_148444336 3.025 ENSMUST00000060095.8
ENSMUST00000100772.3
Tmtc1

transmembrane and tetratricopeptide repeat containing 1

chr2_-_130642770 3.010 ENSMUST00000045761.6
Lzts3
leucine zipper, putative tumor suppressor family member 3
chr19_-_4283033 2.981 ENSMUST00000167215.1
ENSMUST00000056888.6
Ankrd13d

ankyrin repeat domain 13 family, member D

chr5_+_64803513 2.749 ENSMUST00000165536.1
Klf3
Kruppel-like factor 3 (basic)
chr16_+_44173239 2.743 ENSMUST00000119746.1
Gm608
predicted gene 608
chr8_-_34965631 2.739 ENSMUST00000033929.4
Tnks
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr13_-_107022027 2.732 ENSMUST00000117539.1
ENSMUST00000122233.1
ENSMUST00000022204.9
ENSMUST00000159772.1
Kif2a



kinesin family member 2A



chr11_-_97574040 2.730 ENSMUST00000107593.1
Srcin1
SRC kinase signaling inhibitor 1
chr2_-_5714490 2.694 ENSMUST00000044009.7
Camk1d
calcium/calmodulin-dependent protein kinase ID
chr3_+_117575268 2.665 ENSMUST00000039564.6
4833424O15Rik
RIKEN cDNA 4833424O15 gene
chr16_-_96082389 2.664 ENSMUST00000099502.2
ENSMUST00000023631.8
ENSMUST00000113829.1
ENSMUST00000153398.1
Brwd1



bromodomain and WD repeat domain containing 1



chr2_-_173276144 2.659 ENSMUST00000139306.1
Pmepa1
prostate transmembrane protein, androgen induced 1
chr17_-_17624458 2.607 ENSMUST00000041047.2
Lnpep
leucyl/cystinyl aminopeptidase
chr18_+_32938955 2.597 ENSMUST00000042868.4
Camk4
calcium/calmodulin-dependent protein kinase IV
chr8_-_41133697 2.580 ENSMUST00000155055.1
ENSMUST00000059115.6
ENSMUST00000145860.1
Mtus1


mitochondrial tumor suppressor 1


chr1_-_22805994 2.575 ENSMUST00000097808.4
Rims1
regulating synaptic membrane exocytosis 1
chr9_+_89909775 2.568 ENSMUST00000034912.4
ENSMUST00000034909.4
Rasgrf1

RAS protein-specific guanine nucleotide-releasing factor 1

chr7_-_27396542 2.526 ENSMUST00000108363.1
Sptbn4
spectrin beta, non-erythrocytic 4
chr18_+_35965088 2.525 ENSMUST00000175734.1
Psd2
pleckstrin and Sec7 domain containing 2
chr12_-_79007276 2.513 ENSMUST00000056660.6
ENSMUST00000174721.1
Tmem229b

transmembrane protein 229B

chr10_-_54075730 2.500 ENSMUST00000105469.1
ENSMUST00000003843.8
Man1a

mannosidase 1, alpha

chr2_-_45113255 2.481 ENSMUST00000068415.4
ENSMUST00000127520.1
Zeb2

zinc finger E-box binding homeobox 2

chr18_+_35965036 2.477 ENSMUST00000176873.1
ENSMUST00000177432.1
Psd2

pleckstrin and Sec7 domain containing 2

chr11_+_24076529 2.455 ENSMUST00000148087.1
Gm12063
predicted gene 12063
chr5_-_65492984 2.435 ENSMUST00000139122.1
Smim14
small integral membrane protein 14
chr9_-_44881274 2.405 ENSMUST00000002095.3
ENSMUST00000114689.1
ENSMUST00000128768.1
Kmt2a


lysine (K)-specific methyltransferase 2A


chr5_+_130448801 2.400 ENSMUST00000111288.2
Caln1
calneuron 1
chr7_+_126776939 2.353 ENSMUST00000038614.5
ENSMUST00000170882.1
ENSMUST00000106359.1
ENSMUST00000106357.1
ENSMUST00000145762.1
ENSMUST00000132643.1
ENSMUST00000106356.1
Ypel3






yippee-like 3 (Drosophila)






chr2_+_140395309 2.336 ENSMUST00000110067.1
ENSMUST00000110064.1
ENSMUST00000110063.1
ENSMUST00000110062.1
ENSMUST00000078027.5
ENSMUST00000043836.7
Macrod2





MACRO domain containing 2





chr11_+_23306910 2.315 ENSMUST00000137823.1
Usp34
ubiquitin specific peptidase 34
chr4_+_139622842 2.296 ENSMUST00000039818.9
Aldh4a1
aldehyde dehydrogenase 4 family, member A1
chr18_+_36281069 2.271 ENSMUST00000051301.3
Pura
purine rich element binding protein A
chr4_+_83525540 2.239 ENSMUST00000053414.6
ENSMUST00000126429.1
Ccdc171

coiled-coil domain containing 171

chr2_+_128967383 2.148 ENSMUST00000110320.2
ENSMUST00000110319.2
Zc3h6

zinc finger CCCH type containing 6

chr17_+_22361453 2.084 ENSMUST00000149699.1
ENSMUST00000088765.2
ENSMUST00000072477.4
ENSMUST00000121315.1
Zfp758



zinc finger protein 758



chr2_-_45113216 2.078 ENSMUST00000124942.1
Zeb2
zinc finger E-box binding homeobox 2
chr5_-_86172747 2.049 ENSMUST00000039373.7
Uba6
ubiquitin-like modifier activating enzyme 6
chr10_-_54075702 2.024 ENSMUST00000105470.1
Man1a
mannosidase 1, alpha
chr9_-_108190352 2.020 ENSMUST00000035208.7
Bsn
bassoon
chr4_-_25800239 1.979 ENSMUST00000108199.1
Fut9
fucosyltransferase 9
chr9_+_46012822 1.970 ENSMUST00000120463.2
ENSMUST00000120247.1
Sik3

SIK family kinase 3

chr7_+_122289297 1.970 ENSMUST00000064989.5
ENSMUST00000064921.4
Prkcb

protein kinase C, beta

chr16_-_34514084 1.944 ENSMUST00000089655.5
Kalrn
kalirin, RhoGEF kinase
chr17_+_46383725 1.914 ENSMUST00000113481.1
ENSMUST00000138127.1
Zfp318

zinc finger protein 318

chr5_-_100159261 1.913 ENSMUST00000139520.1
Tmem150c
transmembrane protein 150C
chr17_-_35074485 1.901 ENSMUST00000007259.3
Ly6g6d
lymphocyte antigen 6 complex, locus G6D
chr12_+_71015966 1.872 ENSMUST00000046305.5
Arid4a
AT rich interactive domain 4A (RBP1-like)
chr10_-_59616667 1.851 ENSMUST00000020312.6
Mcu
mitochondrial calcium uniporter
chr8_+_105348163 1.850 ENSMUST00000073149.5
Slc9a5
solute carrier family 9 (sodium/hydrogen exchanger), member 5
chrX_+_159532674 1.809 ENSMUST00000057180.6
A830080D01Rik
RIKEN cDNA A830080D01 gene
chr5_+_135064206 1.769 ENSMUST00000071263.5
Dnajc30
DnaJ (Hsp40) homolog, subfamily C, member 30
chr1_+_36511867 1.755 ENSMUST00000001166.7
ENSMUST00000097776.3
Cnnm3

cyclin M3

chr11_-_86357570 1.752 ENSMUST00000043624.8
Med13
mediator complex subunit 13
chr17_+_37050631 1.745 ENSMUST00000172792.1
ENSMUST00000174347.1
Gabbr1

gamma-aminobutyric acid (GABA) B receptor, 1

chr6_-_122340200 1.740 ENSMUST00000159384.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr5_-_106696530 1.737 ENSMUST00000137285.1
ENSMUST00000124263.1
ENSMUST00000112695.1
ENSMUST00000155495.1
ENSMUST00000135108.1
Zfp644




zinc finger protein 644




chr2_-_45117349 1.717 ENSMUST00000176438.2
Zeb2
zinc finger E-box binding homeobox 2
chr11_-_69801716 1.662 ENSMUST00000011285.4
ENSMUST00000102585.1
Fgf11

fibroblast growth factor 11

chr9_+_46012810 1.661 ENSMUST00000126865.1
Sik3
SIK family kinase 3
chr13_+_18948344 1.650 ENSMUST00000003345.7
Amph
amphiphysin
chr11_-_100770926 1.610 ENSMUST00000139341.1
ENSMUST00000017891.7
Ghdc

GH3 domain containing

chr11_-_116307168 1.600 ENSMUST00000124281.1
Exoc7
exocyst complex component 7
chr1_-_72536930 1.583 ENSMUST00000047786.5
March4
membrane-associated ring finger (C3HC4) 4
chr10_-_84440591 1.579 ENSMUST00000020220.8
Nuak1
NUAK family, SNF1-like kinase, 1
chr18_+_61045139 1.571 ENSMUST00000025522.4
ENSMUST00000115274.1
Pdgfrb

platelet derived growth factor receptor, beta polypeptide

chr2_+_37452231 1.542 ENSMUST00000148470.1
ENSMUST00000066055.3
ENSMUST00000112920.1
Rabgap1


RAB GTPase activating protein 1


chr10_-_76345254 1.520 ENSMUST00000036033.7
ENSMUST00000160048.1
ENSMUST00000105417.3
Dip2a


DIP2 disco-interacting protein 2 homolog A (Drosophila)


chr12_-_27342696 1.505 ENSMUST00000079063.5
Sox11
SRY-box containing gene 11
chr3_+_117575227 1.491 ENSMUST00000106473.2
4833424O15Rik
RIKEN cDNA 4833424O15 gene
chr9_+_21936986 1.490 ENSMUST00000046371.6
BC018242
cDNA sequence BC018242
chr11_+_23306884 1.488 ENSMUST00000180046.1
Usp34
ubiquitin specific peptidase 34
chr14_+_21750525 1.486 ENSMUST00000022292.3
Samd8
sterile alpha motif domain containing 8
chr17_-_22361400 1.479 ENSMUST00000115535.2
Zfp944
zinc finger protein 944
chr7_-_80403315 1.470 ENSMUST00000147150.1
Furin
furin (paired basic amino acid cleaving enzyme)
chr1_+_158362330 1.470 ENSMUST00000170718.1
Astn1
astrotactin 1
chr1_+_55406163 1.470 ENSMUST00000042986.8
Plcl1
phospholipase C-like 1
chr7_-_80402743 1.427 ENSMUST00000122232.1
Furin
furin (paired basic amino acid cleaving enzyme)
chr5_+_30588078 1.425 ENSMUST00000066295.2
Kcnk3
potassium channel, subfamily K, member 3
chr16_+_84834901 1.416 ENSMUST00000114184.1
Gabpa
GA repeat binding protein, alpha
chr8_+_93810832 1.388 ENSMUST00000034198.8
ENSMUST00000125716.1
Gnao1

guanine nucleotide binding protein, alpha O

chr19_-_29812952 1.387 ENSMUST00000099525.3
Ranbp6
RAN binding protein 6
chr4_+_129985098 1.386 ENSMUST00000106017.1
ENSMUST00000121049.1
Bai2

brain-specific angiogenesis inhibitor 2

chr12_+_71831064 1.383 ENSMUST00000085299.2
Daam1
dishevelled associated activator of morphogenesis 1
chr7_+_127511976 1.360 ENSMUST00000098025.4
Srcap
Snf2-related CREBBP activator protein
chr10_-_118868903 1.354 ENSMUST00000004281.8
Dyrk2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr15_+_25414175 1.349 ENSMUST00000069992.5
Gm5468
predicted gene 5468
chr7_+_28180226 1.347 ENSMUST00000172467.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chrX_-_147554050 1.342 ENSMUST00000112819.2
ENSMUST00000136789.1
Lrch2

leucine-rich repeats and calponin homology (CH) domain containing 2

chr19_-_43674844 1.335 ENSMUST00000046038.7
Slc25a28
solute carrier family 25, member 28
chrX_-_73659724 1.332 ENSMUST00000114473.1
ENSMUST00000002087.7
Pnck

pregnancy upregulated non-ubiquitously expressed CaM kinase

chr2_-_25501717 1.332 ENSMUST00000015227.3
C8g
complement component 8, gamma polypeptide
chr2_+_128818104 1.303 ENSMUST00000110325.1
Tmem87b
transmembrane protein 87B
chr6_+_87042838 1.263 ENSMUST00000113658.1
ENSMUST00000113657.1
ENSMUST00000113655.1
ENSMUST00000032057.7
Gfpt1



glutamine fructose-6-phosphate transaminase 1



chr1_+_42697146 1.257 ENSMUST00000054883.2
Pou3f3
POU domain, class 3, transcription factor 3
chr15_+_89499598 1.247 ENSMUST00000109309.1
Shank3
SH3/ankyrin domain gene 3
chr15_+_80173642 1.239 ENSMUST00000044970.6
Mgat3
mannoside acetylglucosaminyltransferase 3
chr11_-_3863895 1.226 ENSMUST00000070552.7
Osbp2
oxysterol binding protein 2
chr17_-_32947372 1.208 ENSMUST00000139353.1
Cyp4f13
cytochrome P450, family 4, subfamily f, polypeptide 13
chr11_+_103133303 1.193 ENSMUST00000107037.1
Hexim2
hexamethylene bis-acetamide inducible 2
chr7_-_4778141 1.159 ENSMUST00000094892.5
Il11
interleukin 11
chr10_-_80139347 1.152 ENSMUST00000105369.1
Dos
downstream of Stk11
chr1_-_16519284 1.146 ENSMUST00000162751.1
ENSMUST00000027052.6
ENSMUST00000149320.2
Stau2


staufen (RNA binding protein) homolog 2 (Drosophila)


chr17_-_32947389 1.141 ENSMUST00000075253.6
Cyp4f13
cytochrome P450, family 4, subfamily f, polypeptide 13
chr4_+_97777780 1.139 ENSMUST00000107062.2
ENSMUST00000052018.5
ENSMUST00000107057.1
Nfia


nuclear factor I/A


chr1_-_168431896 1.125 ENSMUST00000176540.1
Pbx1
pre B cell leukemia homeobox 1
chr11_+_103133333 1.121 ENSMUST00000124928.1
ENSMUST00000062530.4
Hexim2

hexamethylene bis-acetamide inducible 2

chr4_-_126533472 1.119 ENSMUST00000084289.4
Ago4
argonaute RISC catalytic subunit 4
chr7_+_28180272 1.112 ENSMUST00000173223.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr14_+_76414929 1.094 ENSMUST00000110888.1
Tsc22d1
TSC22 domain family, member 1
chr11_-_102296618 1.084 ENSMUST00000107132.2
ENSMUST00000073234.2
Atxn7l3

ataxin 7-like 3

chr15_+_12117848 1.071 ENSMUST00000128475.1
ENSMUST00000134277.1
Zfr

zinc finger RNA binding protein

chr11_-_71033462 1.062 ENSMUST00000156068.2
6330403K07Rik
RIKEN cDNA 6330403K07 gene
chr2_+_128818295 1.058 ENSMUST00000178354.1
ENSMUST00000152210.1
Tmem87b

transmembrane protein 87B

chr19_+_57361009 1.046 ENSMUST00000036407.4
Fam160b1
family with sequence similarity 160, member B1
chr2_-_90580578 1.040 ENSMUST00000168621.2
Ptprj
protein tyrosine phosphatase, receptor type, J
chr11_-_116306652 1.035 ENSMUST00000126731.1
Exoc7
exocyst complex component 7
chr13_-_103920508 1.023 ENSMUST00000053927.5
ENSMUST00000091269.4
ENSMUST00000022222.5
Erbb2ip


Erbb2 interacting protein


chr6_+_125009261 1.015 ENSMUST00000112427.1
Zfp384
zinc finger protein 384
chr16_+_20733104 1.009 ENSMUST00000115423.1
ENSMUST00000007171.6
Chrd

chordin

chr5_+_145114280 0.999 ENSMUST00000141602.1
Arpc1b
actin related protein 2/3 complex, subunit 1B
chr1_-_177258182 0.999 ENSMUST00000111159.1
Akt3
thymoma viral proto-oncogene 3
chr16_-_34263179 0.987 ENSMUST00000114949.1
ENSMUST00000114954.1
Kalrn

kalirin, RhoGEF kinase

chr19_+_6497772 0.983 ENSMUST00000113458.1
ENSMUST00000113459.1
Nrxn2

neurexin II

chr17_+_8801742 0.982 ENSMUST00000089085.2
Pde10a
phosphodiesterase 10A
chr15_-_99457712 0.974 ENSMUST00000161948.1
Nckap5l
NCK-associated protein 5-like
chr7_-_116443439 0.954 ENSMUST00000170430.1
Pik3c2a
phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide
chr2_-_74579379 0.944 ENSMUST00000130586.1
Lnp
limb and neural patterns
chr1_-_168431502 0.943 ENSMUST00000064438.4
Pbx1
pre B cell leukemia homeobox 1
chr4_+_119539716 0.941 ENSMUST00000137560.1
Foxj3
forkhead box J3
chr15_-_38078842 0.932 ENSMUST00000110336.2
Ubr5
ubiquitin protein ligase E3 component n-recognin 5
chr16_-_4213404 0.931 ENSMUST00000023165.6
Crebbp
CREB binding protein
chr11_-_116306696 0.926 ENSMUST00000133468.1
ENSMUST00000106411.3
ENSMUST00000106413.3
ENSMUST00000021147.7
Exoc7



exocyst complex component 7



chr16_-_34262830 0.922 ENSMUST00000114947.1
Kalrn
kalirin, RhoGEF kinase
chr11_-_59964936 0.913 ENSMUST00000062405.7
Rasd1
RAS, dexamethasone-induced 1
chr10_+_43479140 0.902 ENSMUST00000167488.1
ENSMUST00000040147.7
Bend3

BEN domain containing 3

chr1_+_86303221 0.887 ENSMUST00000113306.2
B3gnt7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
chr2_-_91182848 0.855 ENSMUST00000111370.2
ENSMUST00000111376.1
ENSMUST00000099723.2
Madd


MAP-kinase activating death domain


chr13_-_103920295 0.853 ENSMUST00000169083.1
Erbb2ip
Erbb2 interacting protein
chr1_-_36369173 0.848 ENSMUST00000010597.3
Kansl3
KAT8 regulatory NSL complex subunit 3
chr11_-_84870646 0.846 ENSMUST00000018547.2
Ggnbp2
gametogenetin binding protein 2
chr4_+_129984833 0.843 ENSMUST00000120204.1
Bai2
brain-specific angiogenesis inhibitor 2
chr11_+_70562840 0.832 ENSMUST00000072237.6
ENSMUST00000072873.7
Mink1

misshapen-like kinase 1 (zebrafish)

chr4_+_108619925 0.830 ENSMUST00000030320.6
Cc2d1b
coiled-coil and C2 domain containing 1B
chr2_-_28840274 0.827 ENSMUST00000037117.5
ENSMUST00000171404.1
Gtf3c4

general transcription factor IIIC, polypeptide 4

chr7_+_25282784 0.824 ENSMUST00000165239.1
Cic
capicua homolog (Drosophila)
chr7_-_128461630 0.822 ENSMUST00000106226.2
Tial1
Tia1 cytotoxic granule-associated RNA binding protein-like 1
chr2_+_26628441 0.819 ENSMUST00000074240.3
Fam69b
family with sequence similarity 69, member B
chr8_-_121652895 0.803 ENSMUST00000046386.4
Zcchc14
zinc finger, CCHC domain containing 14
chr14_-_70520254 0.803 ENSMUST00000022693.7
Bmp1
bone morphogenetic protein 1
chr4_-_123904826 0.796 ENSMUST00000181292.1
Gm26606
predicted gene, 26606
chr13_-_38960846 0.795 ENSMUST00000021870.4
Slc35b3
solute carrier family 35, member B3
chr11_+_116918844 0.782 ENSMUST00000103027.3
Mgat5b
mannoside acetylglucosaminyltransferase 5, isoenzyme B
chr9_+_109931774 0.778 ENSMUST00000169851.2
Map4
microtubule-associated protein 4
chr7_-_19458494 0.770 ENSMUST00000085715.5
Mark4
MAP/microtubule affinity-regulating kinase 4
chr2_+_174110340 0.766 ENSMUST00000044415.9
Npepl1
aminopeptidase-like 1
chrX_+_161717498 0.757 ENSMUST00000061514.7
Rai2
retinoic acid induced 2
chr17_-_27623263 0.749 ENSMUST00000062397.6
ENSMUST00000176876.1
Nudt3

nudix (nucleotide diphosphate linked moiety X)-type motif 3

chr2_-_91183017 0.749 ENSMUST00000066420.5
Madd
MAP-kinase activating death domain
chr2_+_140395446 0.749 ENSMUST00000110061.1
Macrod2
MACRO domain containing 2
chr8_+_111536492 0.748 ENSMUST00000168428.1
ENSMUST00000171182.1
Znrf1

zinc and ring finger 1

chr11_+_70562980 0.747 ENSMUST00000079244.5
ENSMUST00000102558.4
Mink1

misshapen-like kinase 1 (zebrafish)

chr4_+_28813152 0.744 ENSMUST00000108194.2
ENSMUST00000108191.1
Epha7

Eph receptor A7

chr17_-_27623441 0.743 ENSMUST00000025050.5
Nudt3
nudix (nucleotide diphosphate linked moiety X)-type motif 3
chr9_+_25481547 0.743 ENSMUST00000040677.5
Eepd1
endonuclease/exonuclease/phosphatase family domain containing 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:1902460 transforming growth factor beta activation(GO:0036363) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
1.2 8.7 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
1.0 6.3 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
1.0 16.5 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.9 2.7 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.9 3.6 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.9 5.1 GO:0019695 choline metabolic process(GO:0019695)
0.8 1.6 GO:0038091 VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
0.8 3.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.7 2.9 GO:0090472 dibasic protein processing(GO:0090472)
0.7 2.2 GO:0071544 diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.7 2.0 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.6 3.2 GO:0070305 response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321)
0.6 2.6 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.6 3.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.6 2.4 GO:0043974 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.6 3.4 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.6 3.4 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.5 4.4 GO:0061368 maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.5 1.6 GO:1902277 negative regulation of pancreatic amylase secretion(GO:1902277)
0.5 2.7 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.5 2.0 GO:0021764 amygdala development(GO:0021764)
0.5 1.5 GO:0061303 noradrenergic neuron differentiation(GO:0003357) soft palate development(GO:0060023) cornea development in camera-type eye(GO:0061303)
0.5 2.4 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.5 3.2 GO:0016584 nucleosome positioning(GO:0016584)
0.4 3.6 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.4 1.3 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.4 3.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.4 2.5 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.4 4.9 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.4 3.2 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.4 6.7 GO:0030574 collagen catabolic process(GO:0030574)
0.4 2.0 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.4 2.7 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.4 1.5 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.3 1.4 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.3 1.0 GO:0071579 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092) regulation of zinc ion transport(GO:0071579)
0.3 1.3 GO:0072236 DCT cell differentiation(GO:0072069) metanephric loop of Henle development(GO:0072236) metanephric DCT cell differentiation(GO:0072240)
0.3 1.2 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.3 1.8 GO:0098964 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.3 0.9 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.3 3.6 GO:0035635 entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.3 2.3 GO:0006560 proline metabolic process(GO:0006560)
0.3 1.3 GO:0006041 glucosamine metabolic process(GO:0006041)
0.2 1.7 GO:0032811 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) negative regulation of epinephrine secretion(GO:0032811)
0.2 2.2 GO:0043383 negative T cell selection(GO:0043383) negative thymic T cell selection(GO:0045060)
0.2 0.7 GO:0035106 operant conditioning(GO:0035106)
0.2 1.5 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.2 2.3 GO:0006691 leukotriene metabolic process(GO:0006691)
0.2 0.9 GO:1905077 negative regulation of interleukin-17 secretion(GO:1905077)
0.2 0.9 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076) negative regulation of interferon-beta biosynthetic process(GO:0045358)
0.2 1.9 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.2 1.8 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.2 2.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.2 1.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 4.6 GO:0006491 N-glycan processing(GO:0006491)
0.2 5.6 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2 3.3 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.2 0.8 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.2 0.6 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.2 1.0 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.2 2.0 GO:2000303 regulation of ceramide biosynthetic process(GO:2000303)
0.2 5.9 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.2 2.6 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.2 0.7 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.2 1.2 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.2 0.7 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.2 1.6 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.2 1.4 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.2 2.8 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.2 0.5 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.2 0.8 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.7 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 1.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 2.6 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.1 0.4 GO:0018094 protein polyglycylation(GO:0018094)
0.1 3.8 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 1.1 GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.1 1.5 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 2.6 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.1 0.5 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.1 1.5 GO:0072189 ureter development(GO:0072189)
0.1 0.3 GO:0019085 early viral transcription(GO:0019085)
0.1 2.9 GO:0030325 adrenal gland development(GO:0030325)
0.1 3.8 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.1 0.3 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.1 1.1 GO:1903351 response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
0.1 0.5 GO:0042045 epithelial fluid transport(GO:0042045)
0.1 1.0 GO:0042297 vocal learning(GO:0042297) imitative learning(GO:0098596) observational learning(GO:0098597)
0.1 2.3 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.1 2.6 GO:0043171 peptide catabolic process(GO:0043171)
0.1 3.3 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 0.9 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 0.4 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 2.6 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 1.2 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.1 0.4 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.1 0.8 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 0.7 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 0.4 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 2.5 GO:0007520 myoblast fusion(GO:0007520)
0.1 0.3 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.1 1.9 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.1 2.3 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 0.2 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.1 1.0 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 3.1 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
0.1 1.0 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.2 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.2 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 1.1 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.2 GO:0098706 ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 2.7 GO:0090307 mitotic spindle assembly(GO:0090307)
0.0 0.4 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 3.8 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.6 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.2 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 1.3 GO:0006826 iron ion transport(GO:0006826)
0.0 0.8 GO:0061036 positive regulation of cartilage development(GO:0061036)
0.0 0.1 GO:0021998 neural plate mediolateral regionalization(GO:0021998) mesoderm structural organization(GO:0048338) paraxial mesoderm structural organization(GO:0048352) positive regulation of cardiac ventricle development(GO:1904414)
0.0 0.7 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 0.5 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.0 0.3 GO:0097186 amelogenesis(GO:0097186)
0.0 0.3 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.1 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 1.3 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 1.7 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.2 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.0 2.6 GO:0007631 feeding behavior(GO:0007631)
0.0 0.7 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.8 GO:0051926 negative regulation of calcium ion transport(GO:0051926)
0.0 1.1 GO:0048286 lung alveolus development(GO:0048286)
0.0 1.5 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.1 GO:2001184 regulation of interleukin-12 secretion(GO:2001182) positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 1.2 GO:0046888 negative regulation of hormone secretion(GO:0046888)
0.0 0.1 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.0 2.6 GO:0006402 mRNA catabolic process(GO:0006402)
0.0 0.2 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.7 GO:0043631 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.0 0.1 GO:0010878 cholesterol storage(GO:0010878)
0.0 0.7 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.4 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 0.4 GO:0009411 response to UV(GO:0009411)
0.0 0.2 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.7 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.4 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.8 GO:0030010 establishment of cell polarity(GO:0030010)
0.0 0.5 GO:0008156 negative regulation of DNA replication(GO:0008156)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 6.8 GO:0030934 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
1.1 3.2 GO:0098855 HCN channel complex(GO:0098855)
0.9 4.6 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.6 3.4 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.4 2.5 GO:0008091 spectrin(GO:0008091)
0.4 1.9 GO:1990246 uniplex complex(GO:1990246)
0.3 1.7 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.3 5.1 GO:0043083 synaptic cleft(GO:0043083)
0.3 3.6 GO:0032584 growth cone membrane(GO:0032584)
0.2 0.7 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.2 2.3 GO:0001739 sex chromatin(GO:0001739)
0.2 3.2 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.2 2.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 4.9 GO:0030673 axolemma(GO:0030673)
0.1 2.7 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 2.7 GO:0097228 sperm principal piece(GO:0097228)
0.1 1.1 GO:0070578 RISC-loading complex(GO:0070578)
0.1 12.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 2.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.8 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 1.3 GO:0046930 pore complex(GO:0046930)
0.1 6.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 1.8 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.7 GO:0042382 paraspeckles(GO:0042382)
0.1 0.2 GO:0031251 PAN complex(GO:0031251)
0.1 0.6 GO:0042599 lamellar body(GO:0042599)
0.1 2.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 3.8 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 2.4 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 0.9 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 3.8 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 2.7 GO:0031901 early endosome membrane(GO:0031901)
0.1 4.5 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 2.5 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 1.5 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.3 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 5.3 GO:0030175 filopodium(GO:0030175)
0.1 5.5 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.0 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.4 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 7.0 GO:0001650 fibrillar center(GO:0001650)
0.0 5.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.7 GO:0016592 mediator complex(GO:0016592)
0.0 0.7 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.4 GO:0097440 apical dendrite(GO:0097440)
0.0 1.2 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.5 GO:0000124 SAGA complex(GO:0000124)
0.0 2.0 GO:0031526 brush border membrane(GO:0031526)
0.0 2.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.2 GO:0060170 ciliary membrane(GO:0060170)
0.0 1.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 1.0 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 1.6 GO:0005795 Golgi stack(GO:0005795)
0.0 0.4 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 5.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 4.2 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 2.4 GO:0005923 bicellular tight junction(GO:0005923)
0.0 1.7 GO:0043195 terminal bouton(GO:0043195)
0.0 1.4 GO:0031514 motile cilium(GO:0031514)
0.0 0.8 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 6.1 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 1.2 GO:0005930 axoneme(GO:0005930)
0.0 2.3 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.7 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 1.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.1 GO:0004104 cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.8 3.2 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.6 2.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.5 4.5 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.5 2.0 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.4 9.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.4 2.0 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.4 2.4 GO:0045322 unmethylated CpG binding(GO:0045322)
0.4 2.2 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.3 2.7 GO:0097322 7SK snRNA binding(GO:0097322)
0.3 2.0 GO:0035184 histone threonine kinase activity(GO:0035184)
0.3 1.6 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.3 1.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.3 1.5 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.3 1.7 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.3 4.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.3 0.8 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.3 2.9 GO:0048406 nerve growth factor binding(GO:0048406)
0.2 2.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.2 1.4 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.2 1.8 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.2 8.9 GO:0070412 R-SMAD binding(GO:0070412)
0.2 1.3 GO:0019841 retinol binding(GO:0019841)
0.2 1.9 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.2 1.0 GO:0045545 syndecan binding(GO:0045545)
0.2 9.0 GO:0005158 insulin receptor binding(GO:0005158)
0.2 1.7 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 2.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 5.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 0.7 GO:0050436 microfibril binding(GO:0050436)
0.2 0.8 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.2 0.9 GO:0043426 MRF binding(GO:0043426)
0.1 1.0 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 4.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 1.5 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1 3.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.4 GO:0070736 protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736)
0.1 1.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 3.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.6 GO:0070330 aromatase activity(GO:0070330)
0.1 1.3 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.1 2.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.5 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 2.3 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 2.2 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 2.5 GO:0030506 ankyrin binding(GO:0030506)
0.1 3.1 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 1.0 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.8 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 1.9 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 2.0 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.6 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 0.2 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.9 GO:0000182 rDNA binding(GO:0000182)
0.1 0.5 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 1.0 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 0.4 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.9 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 1.3 GO:0008483 transaminase activity(GO:0008483)
0.1 0.2 GO:0031752 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.1 0.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 3.8 GO:0019003 GDP binding(GO:0019003)
0.1 3.6 GO:0005518 collagen binding(GO:0005518)
0.1 3.0 GO:0019213 deacetylase activity(GO:0019213)
0.1 2.6 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.1 3.0 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 0.6 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.6 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 4.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.3 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.2 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.5 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 1.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.5 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 1.4 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 1.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.8 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.8 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 3.8 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 1.1 GO:0042805 actinin binding(GO:0042805)
0.0 0.9 GO:0035064 methylated histone binding(GO:0035064)
0.0 2.7 GO:0008083 growth factor activity(GO:0008083)
0.0 1.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 6.0 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.0 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.7 GO:0016866 intramolecular transferase activity(GO:0016866)
0.0 1.0 GO:0017091 AU-rich element binding(GO:0017091)
0.0 1.5 GO:0043621 protein self-association(GO:0043621)
0.0 0.8 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.0 1.3 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 2.5 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 3.4 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 1.7 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.9 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.5 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 1.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 3.6 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.4 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.1 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.7 GO:0030507 spectrin binding(GO:0030507)
0.0 2.4 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.1 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.5 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.9 GO:0004860 protein kinase inhibitor activity(GO:0004860)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.3 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.2 9.7 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.2 4.4 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.2 3.0 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.1 2.6 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.1 5.2 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.1 1.0 PID_AVB3_INTEGRIN_PATHWAY Integrins in angiogenesis
0.1 6.2 PID_CDC42_PATHWAY CDC42 signaling events
0.1 1.0 PID_S1P_S1P3_PATHWAY S1P3 pathway
0.1 2.9 NABA_COLLAGENS Genes encoding collagen proteins
0.1 0.8 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.1 2.0 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 1.3 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 1.7 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 1.2 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.0 3.0 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 2.2 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 2.9 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.6 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.0 0.8 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.9 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 1.7 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.8 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 4.7 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 0.5 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.3 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.3 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 2.0 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.8 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.9 2.6 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.3 2.9 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.3 2.6 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.2 5.1 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.2 1.4 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 2.9 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.2 10.7 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.1 1.7 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.4 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.1 1.3 REACTOME_COMPLEMENT_CASCADE Genes involved in Complement cascade
0.1 7.4 REACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS Genes involved in Post NMDA receptor activation events
0.1 4.1 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 0.3 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.1 2.0 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 2.5 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.0 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.0 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 3.2 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.1 1.0 REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 3.2 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 4.2 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.1 1.3 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1 0.9 REACTOME_KERATAN_SULFATE_BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 1.5 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.0 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.4 REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.5 REACTOME_ACYL_CHAIN_REMODELLING_OF_PC Genes involved in Acyl chain remodelling of PC
0.0 0.7 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.8 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.7 REACTOME_G_ALPHA_S_SIGNALLING_EVENTS Genes involved in G alpha (s) signalling events
0.0 2.1 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.7 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME_ELONGATION_ARREST_AND_RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.6 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.8 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 2.3 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 1.2 REACTOME_DNA_REPAIR Genes involved in DNA Repair