Motif ID: Etv6

Z-value: 0.772


Transcription factors associated with Etv6:

Gene SymbolEntrez IDGene Name
Etv6 ENSMUSG00000030199.10 Etv6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Etv6mm10_v2_chr6_+_134035953_1340359730.144.0e-01Click!


Activity profile for motif Etv6.

activity profile for motif Etv6


Sorted Z-values histogram for motif Etv6

Sorted Z-values for motif Etv6



Network of associatons between targets according to the STRING database.



First level regulatory network of Etv6

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_74601441 0.961 ENSMUST00000087183.4
ENSMUST00000148456.1
ENSMUST00000113694.1
Stk36


serine/threonine kinase 36


chr10_-_67285180 0.957 ENSMUST00000159002.1
ENSMUST00000077839.6
Nrbf2

nuclear receptor binding factor 2

chr4_+_155943824 0.899 ENSMUST00000103175.1
ENSMUST00000166489.1
ENSMUST00000024056.3
ENSMUST00000136492.1
ENSMUST00000105583.2
ENSMUST00000152536.1
Ube2j2





ubiquitin-conjugating enzyme E2J 2





chr12_+_102757965 0.858 ENSMUST00000046404.6
Ubr7
ubiquitin protein ligase E3 component n-recognin 7 (putative)
chr1_+_74601548 0.846 ENSMUST00000087186.4
Stk36
serine/threonine kinase 36
chr2_+_168230597 0.841 ENSMUST00000099071.3
Mocs3
molybdenum cofactor synthesis 3
chr9_+_48450327 0.833 ENSMUST00000165252.1
Gm5616
predicted gene 5616
chr1_-_183221529 0.828 ENSMUST00000003035.5
Disp1
dispatched homolog 1 (Drosophila)
chr4_+_118409331 0.824 ENSMUST00000084319.4
ENSMUST00000106384.3
ENSMUST00000126089.1
ENSMUST00000073881.1
ENSMUST00000019229.8
ENSMUST00000144577.1
Med8





mediator of RNA polymerase II transcription, subunit 8 homolog (yeast)





chr3_-_89764581 0.809 ENSMUST00000029562.3
Chrnb2
cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)
chr8_-_72571033 0.809 ENSMUST00000058733.8
ENSMUST00000167290.1
Smim7

small integral membrane protein 7

chr7_-_105744312 0.796 ENSMUST00000141116.1
Taf10
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr4_-_98383232 0.764 ENSMUST00000143116.1
ENSMUST00000030292.5
ENSMUST00000102793.4
Tm2d1


TM2 domain containing 1


chr4_-_136886187 0.747 ENSMUST00000046384.8
C1qb
complement component 1, q subcomponent, beta polypeptide
chr10_-_31609184 0.733 ENSMUST00000081989.6
Rnf217
ring finger protein 217
chr13_+_4191163 0.725 ENSMUST00000021634.2
Akr1c13
aldo-keto reductase family 1, member C13
chr11_-_35834492 0.724 ENSMUST00000018992.3
Rars
arginyl-tRNA synthetase
chr5_-_149636164 0.719 ENSMUST00000076410.4
Hsph1
heat shock 105kDa/110kDa protein 1
chr6_-_120822680 0.693 ENSMUST00000019354.8
Atp6v1e1
ATPase, H+ transporting, lysosomal V1 subunit E1
chr3_+_95217417 0.683 ENSMUST00000181819.1
Gm16740
predicted gene, 16740
chr9_+_107563246 0.671 ENSMUST00000010198.3
Tusc2
tumor suppressor candidate 2
chr8_-_107056650 0.663 ENSMUST00000034391.3
ENSMUST00000095517.5
Cog8

component of oligomeric golgi complex 8

chr5_-_31220491 0.658 ENSMUST00000031032.7
Ppm1g
protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform
chr7_-_46919915 0.655 ENSMUST00000143413.1
ENSMUST00000014546.8
Tsg101

tumor susceptibility gene 101

chr5_-_116024452 0.648 ENSMUST00000031486.7
Prkab1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr4_+_155943992 0.635 ENSMUST00000118192.1
ENSMUST00000105582.1
ENSMUST00000105581.3
Ube2j2


ubiquitin-conjugating enzyme E2J 2


chr9_-_78489141 0.635 ENSMUST00000154207.1
Eef1a1
eukaryotic translation elongation factor 1 alpha 1
chr11_+_88204380 0.632 ENSMUST00000024486.7
Mrps23
mitochondrial ribosomal protein S23
chr4_+_125066672 0.630 ENSMUST00000052183.6
Snip1
Smad nuclear interacting protein 1
chr3_+_89430261 0.627 ENSMUST00000060061.4
Pygo2
pygopus 2
chr5_+_124629050 0.622 ENSMUST00000037865.8
Atp6v0a2
ATPase, H+ transporting, lysosomal V0 subunit A2
chr14_+_47298260 0.621 ENSMUST00000166743.1
Mapk1ip1l
mitogen-activated protein kinase 1 interacting protein 1-like
chrX_-_94212638 0.620 ENSMUST00000113922.1
Eif2s3x
eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked
chr11_-_16508069 0.620 ENSMUST00000109641.1
Sec61g
SEC61, gamma subunit
chr18_+_62548911 0.619 ENSMUST00000055725.4
ENSMUST00000162365.1
Spink10

serine peptidase inhibitor, Kazal type 10

chr15_+_12824815 0.612 ENSMUST00000169061.1
Drosha
drosha, ribonuclease type III
chr5_-_110269816 0.612 ENSMUST00000059229.9
ENSMUST00000112505.2
Pgam5

phosphoglycerate mutase family member 5

chr2_+_127208358 0.604 ENSMUST00000103220.3
Snrnp200
small nuclear ribonucleoprotein 200 (U5)
chr1_+_4808237 0.600 ENSMUST00000131119.1
Lypla1
lysophospholipase 1
chr1_+_179546303 0.597 ENSMUST00000040706.8
Cnst
consortin, connexin sorting protein
chr4_-_124851152 0.592 ENSMUST00000185036.1
1110065P20Rik
RIKEN cDNA 1110065P20 gene
chrX_-_94212685 0.592 ENSMUST00000050328.8
Eif2s3x
eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked
chr15_-_98145698 0.590 ENSMUST00000123626.1
Asb8
ankyrin repeat and SOCS box-containing 8
chr19_+_5366764 0.587 ENSMUST00000025759.7
Eif1ad
eukaryotic translation initiation factor 1A domain containing
chr1_-_36244245 0.583 ENSMUST00000046875.7
Uggt1
UDP-glucose glycoprotein glucosyltransferase 1
chr16_+_3872368 0.579 ENSMUST00000151988.1
Naa60
N(alpha)-acetyltransferase 60, NatF catalytic subunit
chr12_+_109459843 0.571 ENSMUST00000173812.1
Dlk1
delta-like 1 homolog (Drosophila)
chr12_-_84970814 0.562 ENSMUST00000165886.1
ENSMUST00000167448.1
ENSMUST00000043169.7
Arel1


apoptosis resistant E3 ubiquitin protein ligase 1


chr6_-_113740675 0.562 ENSMUST00000032440.4
Sec13
SEC13 homolog (S. cerevisiae)
chr1_+_33669816 0.559 ENSMUST00000051203.5
1700001G17Rik
RIKEN cDNA 1700001G17 gene
chr14_-_31001588 0.553 ENSMUST00000162092.1
ENSMUST00000160342.1
Spcs1

signal peptidase complex subunit 1 homolog (S. cerevisiae)

chr15_-_98145625 0.550 ENSMUST00000059112.5
Asb8
ankyrin repeat and SOCS box-containing 8
chr3_-_94886945 0.549 ENSMUST00000005923.6
Psmb4
proteasome (prosome, macropain) subunit, beta type 4
chr13_-_74208661 0.547 ENSMUST00000035934.5
Exoc3
exocyst complex component 3
chr15_-_51865448 0.540 ENSMUST00000022925.8
Eif3h
eukaryotic translation initiation factor 3, subunit H
chr17_+_27839974 0.525 ENSMUST00000071006.7
Snrpc
U1 small nuclear ribonucleoprotein C
chr7_-_67645195 0.519 ENSMUST00000032775.5
ENSMUST00000053950.2
Lrrc28

leucine rich repeat containing 28

chr5_+_147860615 0.514 ENSMUST00000031654.6
Pomp
proteasome maturation protein
chrX_-_141725181 0.509 ENSMUST00000067841.7
Irs4
insulin receptor substrate 4
chr13_+_20090500 0.507 ENSMUST00000165249.2
Elmo1
engulfment and cell motility 1
chr6_-_88518760 0.505 ENSMUST00000032168.5
Sec61a1
Sec61 alpha 1 subunit (S. cerevisiae)
chr4_+_107178399 0.502 ENSMUST00000030361.4
ENSMUST00000128123.1
ENSMUST00000106753.1
Tmem59


transmembrane protein 59


chr15_+_12824841 0.502 ENSMUST00000090292.5
Drosha
drosha, ribonuclease type III
chr5_-_149636331 0.492 ENSMUST00000074846.7
ENSMUST00000110498.1
ENSMUST00000127977.1
ENSMUST00000132412.1
Hsph1



heat shock 105kDa/110kDa protein 1



chrX_+_7884244 0.491 ENSMUST00000115663.3
Slc35a2
solute carrier family 35 (UDP-galactose transporter), member A2
chr5_-_116024475 0.489 ENSMUST00000111999.1
Prkab1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr7_+_127233227 0.488 ENSMUST00000056232.6
Zfp553
zinc finger protein 553
chr19_+_44562841 0.483 ENSMUST00000040455.4
Hif1an
hypoxia-inducible factor 1, alpha subunit inhibitor
chr13_+_20090538 0.480 ENSMUST00000072519.5
Elmo1
engulfment and cell motility 1
chr7_-_144470714 0.478 ENSMUST00000033407.6
Cttn
cortactin
chr15_-_85811644 0.472 ENSMUST00000144067.1
ENSMUST00000134631.1
ENSMUST00000154814.1
ENSMUST00000071876.6
ENSMUST00000150995.1
Cdpf1




cysteine rich, DPF motif domain containing 1




chr11_-_115699461 0.470 ENSMUST00000106497.1
Grb2
growth factor receptor bound protein 2
chr17_-_15498263 0.470 ENSMUST00000014913.9
Psmb1
proteasome (prosome, macropain) subunit, beta type 1
chr3_+_96172327 0.469 ENSMUST00000076372.4
Sf3b4
splicing factor 3b, subunit 4
chr9_+_108508005 0.467 ENSMUST00000006838.8
ENSMUST00000134939.1
Qars

glutaminyl-tRNA synthetase

chr4_-_59783800 0.465 ENSMUST00000107526.1
ENSMUST00000095063.4
Inip

INTS3 and NABP interacting protein

chr10_+_128805652 0.463 ENSMUST00000026410.1
Dnajc14
DnaJ (Hsp40) homolog, subfamily C, member 14
chr17_+_46711459 0.461 ENSMUST00000002840.8
Pex6
peroxisomal biogenesis factor 6
chr11_-_16508149 0.461 ENSMUST00000109642.1
Sec61g
SEC61, gamma subunit
chr15_-_82047579 0.461 ENSMUST00000166578.1
ENSMUST00000080622.7
Nhp2l1

NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)

chrX_+_20703906 0.460 ENSMUST00000033383.2
Usp11
ubiquitin specific peptidase 11
chr17_+_35135695 0.450 ENSMUST00000174478.1
ENSMUST00000174281.2
ENSMUST00000173550.1
Bag6


BCL2-associated athanogene 6


chr3_-_90213577 0.445 ENSMUST00000170122.2
Rps27
ribosomal protein S27
chr2_+_90904740 0.445 ENSMUST00000111464.1
ENSMUST00000090682.3
Kbtbd4

kelch repeat and BTB (POZ) domain containing 4

chr11_-_115699307 0.445 ENSMUST00000106499.1
Grb2
growth factor receptor bound protein 2
chr10_+_77864623 0.444 ENSMUST00000092366.2
Tspear
thrombospondin type laminin G domain and EAR repeats
chr8_+_124863032 0.444 ENSMUST00000034466.3
ENSMUST00000161986.1
Gnpat

glyceronephosphate O-acyltransferase

chr19_+_8941865 0.443 ENSMUST00000096240.2
Mta2
metastasis-associated gene family, member 2
chr14_-_31001311 0.442 ENSMUST00000161219.1
ENSMUST00000182501.1
Spcs1

signal peptidase complex subunit 1 homolog (S. cerevisiae)

chr2_+_29935413 0.442 ENSMUST00000019859.8
Gle1
GLE1 RNA export mediator (yeast)
chr10_+_42678890 0.437 ENSMUST00000040718.5
Ostm1
osteopetrosis associated transmembrane protein 1
chr3_+_95658771 0.427 ENSMUST00000178686.1
Mcl1
myeloid cell leukemia sequence 1
chr12_-_78861636 0.418 ENSMUST00000021536.7
Atp6v1d
ATPase, H+ transporting, lysosomal V1 subunit D
chr4_+_44012638 0.416 ENSMUST00000107847.3
ENSMUST00000170241.1
Clta

clathrin, light polypeptide (Lca)

chr11_+_88204396 0.416 ENSMUST00000118784.1
ENSMUST00000139170.1
ENSMUST00000107915.3
ENSMUST00000144070.1
Mrps23



mitochondrial ribosomal protein S23



chr11_-_97041395 0.415 ENSMUST00000021251.6
Lrrc46
leucine rich repeat containing 46
chr4_+_44012661 0.408 ENSMUST00000107849.3
ENSMUST00000107851.3
ENSMUST00000107845.3
Clta


clathrin, light polypeptide (Lca)


chr15_+_5185700 0.408 ENSMUST00000081640.5
Ttc33
tetratricopeptide repeat domain 33
chr15_+_5185519 0.407 ENSMUST00000118193.1
ENSMUST00000022751.8
Ttc33

tetratricopeptide repeat domain 33

chrX_+_7884022 0.402 ENSMUST00000115660.4
Slc35a2
solute carrier family 35 (UDP-galactose transporter), member A2
chr2_-_10080322 0.399 ENSMUST00000145530.1
ENSMUST00000026887.7
ENSMUST00000114896.1
ENSMUST00000114897.2
Atp5c1



ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1



chr11_+_106256140 0.395 ENSMUST00000021049.2
Psmc5
protease (prosome, macropain) 26S subunit, ATPase 5
chr3_-_88425094 0.392 ENSMUST00000168755.1
ENSMUST00000057935.6
Slc25a44

solute carrier family 25, member 44

chr1_+_134494628 0.392 ENSMUST00000047978.7
Rabif
RAB interacting factor
chr2_+_32535724 0.391 ENSMUST00000133366.1
Fam102a
family with sequence similarity 102, member A
chr11_+_5955693 0.387 ENSMUST00000002818.8
Ykt6
YKT6 homolog (S. Cerevisiae)
chr1_-_125435694 0.385 ENSMUST00000178474.1
ENSMUST00000027579.10
Actr3

ARP3 actin-related protein 3

chr15_+_58933774 0.382 ENSMUST00000022980.3
Ndufb9
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9
chr4_-_48279544 0.377 ENSMUST00000030028.4
Erp44
endoplasmic reticulum protein 44
chr14_-_101640434 0.376 ENSMUST00000168587.1
Commd6
COMM domain containing 6
chr3_-_95871367 0.376 ENSMUST00000142437.1
ENSMUST00000067298.4
Mrps21

mitochondrial ribosomal protein S21

chr14_+_55591708 0.375 ENSMUST00000019443.8
Rnf31
ring finger protein 31
chr13_-_58128542 0.373 ENSMUST00000007980.6
Hnrnpa0
heterogeneous nuclear ribonucleoprotein A0
chr1_+_4807823 0.366 ENSMUST00000027036.4
ENSMUST00000119612.2
ENSMUST00000137887.1
ENSMUST00000115529.1
ENSMUST00000150971.1
Lypla1




lysophospholipase 1




chr5_-_135744206 0.363 ENSMUST00000153399.1
ENSMUST00000043378.2
Tmem120a

transmembrane protein 120A

chr10_-_14705459 0.363 ENSMUST00000149485.1
ENSMUST00000154132.1
Vta1

Vps20-associated 1 homolog (S. cerevisiae)

chr17_-_35121173 0.361 ENSMUST00000174024.1
Csnk2b
casein kinase 2, beta polypeptide
chr2_+_152226839 0.358 ENSMUST00000099224.3
ENSMUST00000124791.1
ENSMUST00000133119.1
Csnk2a1


casein kinase 2, alpha 1 polypeptide


chr11_-_96916366 0.358 ENSMUST00000144731.1
ENSMUST00000127048.1
Cdk5rap3

CDK5 regulatory subunit associated protein 3

chr2_-_30286312 0.357 ENSMUST00000100219.3
Dolk
dolichol kinase
chr19_+_46599081 0.356 ENSMUST00000138302.2
ENSMUST00000099376.4
Wbp1l

WW domain binding protein 1 like

chr17_-_35121030 0.356 ENSMUST00000174306.1
Csnk2b
casein kinase 2, beta polypeptide
chr6_+_125009665 0.355 ENSMUST00000046064.10
ENSMUST00000152752.1
ENSMUST00000088308.3
ENSMUST00000112425.1
ENSMUST00000084275.5
Zfp384




zinc finger protein 384




chr11_-_120467414 0.351 ENSMUST00000076921.6
Arl16
ADP-ribosylation factor-like 16
chr4_-_40948196 0.348 ENSMUST00000030125.4
ENSMUST00000108089.1
Bag1

BCL2-associated athanogene 1

chr17_+_35135463 0.345 ENSMUST00000173535.1
ENSMUST00000173952.1
Bag6

BCL2-associated athanogene 6

chr8_+_83652670 0.344 ENSMUST00000019577.8
Gipc1
GIPC PDZ domain containing family, member 1
chr2_+_164074122 0.341 ENSMUST00000018353.7
Stk4
serine/threonine kinase 4
chr12_-_102757765 0.340 ENSMUST00000173969.1
ENSMUST00000179263.1
ENSMUST00000046456.6
ENSMUST00000179306.1
AK010878


RP24-234J3.4
cDNA sequence AK010878


Protein AK010878
chr11_-_120457936 0.338 ENSMUST00000137632.1
ENSMUST00000044007.2
Oxld1

oxidoreductase like domain containing 1

chr2_+_132686931 0.338 ENSMUST00000061891.4
1110034G24Rik
RIKEN cDNA 1110034G24 gene
chr6_-_113377712 0.335 ENSMUST00000113107.1
ENSMUST00000113106.1
Tada3

transcriptional adaptor 3

chr15_-_57892358 0.331 ENSMUST00000022993.5
Derl1
Der1-like domain family, member 1
chrX_-_100625901 0.330 ENSMUST00000059099.6
Pdzd11
PDZ domain containing 11
chr7_+_81762947 0.329 ENSMUST00000133034.1
Fam103a1
family with sequence similarity 103, member A1
chr16_-_32868325 0.327 ENSMUST00000089684.3
ENSMUST00000040986.8
ENSMUST00000115105.2
1700021K19Rik


RIKEN cDNA 1700021K19 gene


chr11_-_98400393 0.327 ENSMUST00000128897.1
Pgap3
post-GPI attachment to proteins 3
chr14_-_18331855 0.326 ENSMUST00000022296.6
Ube2e1
ubiquitin-conjugating enzyme E2E 1
chr17_-_35121423 0.326 ENSMUST00000173114.1
Csnk2b
casein kinase 2, beta polypeptide
chrX_+_7884321 0.326 ENSMUST00000096514.3
ENSMUST00000123277.1
Slc35a2

solute carrier family 35 (UDP-galactose transporter), member A2

chr19_-_6084873 0.325 ENSMUST00000160977.1
ENSMUST00000159859.1
Zfpl1

zinc finger like protein 1

chr1_+_91250311 0.324 ENSMUST00000059743.5
ENSMUST00000178627.1
ENSMUST00000171165.1
Ube2f


ubiquitin-conjugating enzyme E2F (putative)


chr5_-_31202215 0.324 ENSMUST00000176245.1
ENSMUST00000177310.1
ENSMUST00000114590.1
Zfp513


zinc finger protein 513


chr5_-_38561658 0.321 ENSMUST00000005234.9
Wdr1
WD repeat domain 1
chr17_+_15396240 0.321 ENSMUST00000055352.6
Fam120b
family with sequence similarity 120, member B
chr9_+_45055166 0.318 ENSMUST00000114664.1
ENSMUST00000093856.3
Mpzl3

myelin protein zero-like 3

chr14_-_101640670 0.318 ENSMUST00000100339.2
Commd6
COMM domain containing 6
chr9_-_21149894 0.318 ENSMUST00000019615.9
Cdc37
cell division cycle 37
chr8_+_113635550 0.318 ENSMUST00000179926.1
Mon1b
MON1 homolog b (yeast)
chr6_+_113378113 0.316 ENSMUST00000171058.1
ENSMUST00000156898.1
Arpc4

actin related protein 2/3 complex, subunit 4

chr1_+_91250482 0.312 ENSMUST00000171112.1
Ube2f
ubiquitin-conjugating enzyme E2F (putative)
chr11_-_79962374 0.311 ENSMUST00000108241.1
ENSMUST00000043152.5
Utp6

UTP6, small subunit (SSU) processome component, homolog (yeast)

chr5_+_143758293 0.311 ENSMUST00000180951.1
D130017N08Rik
RIKEN cDNA D130017N08 gene
chr4_-_119173849 0.308 ENSMUST00000052715.4
ENSMUST00000179290.1
ENSMUST00000154226.1
Zfp691


zinc finger protein 691


chr7_-_125707735 0.308 ENSMUST00000055506.7
Gtf3c1
general transcription factor III C 1
chr4_-_41314877 0.304 ENSMUST00000030145.8
Dcaf12
DDB1 and CUL4 associated factor 12
chr8_-_94601720 0.299 ENSMUST00000034226.6
Fam192a
family with sequence similarity 192, member A
chr1_-_133610253 0.297 ENSMUST00000166915.1
Snrpe
small nuclear ribonucleoprotein E
chr2_-_84715160 0.297 ENSMUST00000035840.5
Zdhhc5
zinc finger, DHHC domain containing 5
chr15_-_34443209 0.296 ENSMUST00000009039.5
Rpl30
ribosomal protein L30
chr5_-_145140238 0.295 ENSMUST00000031627.8
Pdap1
PDGFA associated protein 1
chr7_+_127233044 0.295 ENSMUST00000106312.3
Zfp553
zinc finger protein 553
chr2_-_30967859 0.295 ENSMUST00000028200.8
Tor1a
torsin family 1, member A (torsin A)
chr5_-_139826837 0.295 ENSMUST00000182602.1
ENSMUST00000031531.7
Psmg3

proteasome (prosome, macropain) assembly chaperone 3

chr11_-_96916407 0.293 ENSMUST00000130774.1
Cdk5rap3
CDK5 regulatory subunit associated protein 3
chr8_+_113635787 0.292 ENSMUST00000035777.8
Mon1b
MON1 homolog b (yeast)
chr4_-_133277730 0.291 ENSMUST00000105907.2
Tmem222
transmembrane protein 222
chr17_+_35135174 0.290 ENSMUST00000166426.2
ENSMUST00000025250.7
Bag6

BCL2-associated athanogene 6

chr5_-_138263942 0.284 ENSMUST00000048421.7
ENSMUST00000164203.1
BC037034
BC037034
cDNA sequence BC037034
cDNA sequence BC037034
chr4_+_40948401 0.283 ENSMUST00000030128.5
Chmp5
charged multivesicular body protein 5
chr11_-_98400453 0.282 ENSMUST00000090827.5
Pgap3
post-GPI attachment to proteins 3
chr3_+_95658714 0.278 ENSMUST00000037947.8
Mcl1
myeloid cell leukemia sequence 1
chr17_+_35135196 0.276 ENSMUST00000172571.1
ENSMUST00000173491.1
Bag6

BCL2-associated athanogene 6

chr19_-_45006385 0.276 ENSMUST00000097715.2
Mrpl43
mitochondrial ribosomal protein L43
chr14_-_24486994 0.275 ENSMUST00000026322.7
Polr3a
polymerase (RNA) III (DNA directed) polypeptide A
chr8_-_107588392 0.272 ENSMUST00000044106.4
Psmd7
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
chr3_-_65392579 0.270 ENSMUST00000029414.5
Ssr3
signal sequence receptor, gamma
chr9_+_20644851 0.270 ENSMUST00000161882.1
Ubl5
ubiquitin-like 5
chr11_+_87592145 0.269 ENSMUST00000103179.3
ENSMUST00000092802.5
ENSMUST00000146871.1
Mtmr4


myotubularin related protein 4


chr11_+_120467635 0.268 ENSMUST00000140862.1
ENSMUST00000106205.1
ENSMUST00000106203.1
ENSMUST00000026900.7
Hgs



HGF-regulated tyrosine kinase substrate



chr18_+_12128850 0.267 ENSMUST00000025270.6
Riok3
RIO kinase 3
chr11_+_114668524 0.261 ENSMUST00000106602.3
ENSMUST00000077915.3
ENSMUST00000106599.1
ENSMUST00000082092.4
Rpl38



ribosomal protein L38



chr10_+_83360206 0.261 ENSMUST00000020488.7
D10Wsu102e
DNA segment, Chr 10, Wayne State University 102, expressed
chr17_+_20945311 0.260 ENSMUST00000007708.7
Ppp2r1a
protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform
chr15_+_76331231 0.254 ENSMUST00000023221.6
Gpaa1
GPI anchor attachment protein 1
chr19_-_6084679 0.245 ENSMUST00000161548.1
Zfpl1
zinc finger like protein 1
chr7_-_80947765 0.244 ENSMUST00000026818.5
ENSMUST00000117383.1
ENSMUST00000119980.1
Sec11a


SEC11 homolog A (S. cerevisiae)


chr7_-_80947499 0.241 ENSMUST00000120285.1
Sec11a
SEC11 homolog A (S. cerevisiae)
chr7_+_81762925 0.240 ENSMUST00000042166.4
Fam103a1
family with sequence similarity 103, member A1
chr11_+_58330712 0.240 ENSMUST00000116376.2
Sh3bp5l
SH3 binding domain protein 5 like
chr9_-_79759849 0.239 ENSMUST00000034881.6
Cox7a2
cytochrome c oxidase subunit VIIa 2
chrX_-_134541847 0.238 ENSMUST00000054213.4
Timm8a1
translocase of inner mitochondrial membrane 8A1
chr9_-_22117123 0.238 ENSMUST00000013966.6
Elof1
elongation factor 1 homolog (ELF1, S. cerevisiae)
chr18_-_60848911 0.235 ENSMUST00000177172.1
ENSMUST00000175934.1
ENSMUST00000176630.1
Tcof1


Treacher Collins Franceschetti syndrome 1, homolog


chr4_-_116807574 0.233 ENSMUST00000030451.3
Toe1
target of EGR1, member 1 (nuclear)
chr11_-_75178792 0.232 ENSMUST00000071562.2
Ovca2
candidate tumor suppressor in ovarian cancer 2
chr6_-_113377866 0.231 ENSMUST00000032410.7
Tada3
transcriptional adaptor 3
chr1_-_54926311 0.227 ENSMUST00000179030.1
ENSMUST00000044359.9
Ankrd44

ankyrin repeat domain 44

chr8_+_94601928 0.227 ENSMUST00000060389.8
ENSMUST00000121101.1
Rspry1

ring finger and SPRY domain containing 1

chr4_-_155086271 0.225 ENSMUST00000030914.3
Rer1
RER1 retention in endoplasmic reticulum 1 homolog (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.8 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.3 1.2 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345) positive regulation of NK T cell activation(GO:0051135)
0.3 0.8 GO:0060084 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) synaptic transmission involved in micturition(GO:0060084)
0.2 0.7 GO:0070944 neutrophil mediated killing of bacterium(GO:0070944)
0.2 0.7 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.2 0.8 GO:0018307 tRNA wobble position uridine thiolation(GO:0002143) enzyme active site formation(GO:0018307)
0.2 0.6 GO:0019085 early viral transcription(GO:0019085)
0.2 0.6 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.2 1.1 GO:0035878 nail development(GO:0035878)
0.2 0.7 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.2 1.0 GO:0090005 negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.2 1.4 GO:0036506 maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.2 0.5 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.2 0.5 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.2 1.1 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.2 0.5 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.1 0.7 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 0.6 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.4 GO:0031038 myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519) regulation of bleb assembly(GO:1904170)
0.1 0.1 GO:0031990 mRNA export from nucleus in response to heat stress(GO:0031990)
0.1 0.3 GO:1904569 regulation of selenocysteine incorporation(GO:1904569)
0.1 1.0 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.1 1.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.1 1.5 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.3 GO:1903538 meiotic sister chromatid cohesion, centromeric(GO:0051754) meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.1 0.3 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.6 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.3 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.7 GO:0071569 protein ufmylation(GO:0071569)
0.1 0.7 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.1 0.6 GO:0060046 regulation of acrosome reaction(GO:0060046)
0.1 0.5 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.8 GO:0060539 diaphragm development(GO:0060539)
0.1 0.4 GO:0030913 paranodal junction assembly(GO:0030913)
0.1 0.8 GO:0070365 hepatocyte differentiation(GO:0070365)
0.1 0.5 GO:0048793 pronephros development(GO:0048793)
0.1 0.1 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.1 0.2 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 0.6 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.5 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 0.3 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.5 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.9 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1 0.1 GO:2000157 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.1 0.6 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.1 0.3 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 0.3 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.3 GO:0048318 axial mesoderm development(GO:0048318)
0.0 0.4 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.1 GO:0039533 regulation of MDA-5 signaling pathway(GO:0039533)
0.0 0.2 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.5 GO:0051601 exocyst localization(GO:0051601)
0.0 0.2 GO:0045896 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0 0.7 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0006083 acetate metabolic process(GO:0006083)
0.0 0.4 GO:0023035 CD40 signaling pathway(GO:0023035)
0.0 0.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.5 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.3 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.7 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.0 0.1 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.5 GO:0043248 proteasome assembly(GO:0043248)
0.0 3.2 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.7 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.7 GO:0045116 protein neddylation(GO:0045116)
0.0 0.4 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.4 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.8 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.0 0.7 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.5 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.6 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.1 GO:0032055 negative regulation of translation in response to stress(GO:0032055)
0.0 0.2 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 1.0 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 0.4 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.7 GO:0070266 necroptotic process(GO:0070266)
0.0 0.1 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.2 GO:0006983 ER overload response(GO:0006983)
0.0 0.1 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130) negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.0 0.2 GO:0014029 neural crest formation(GO:0014029)
0.0 1.0 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.1 GO:1901355 response to rapamycin(GO:1901355)
0.0 2.4 GO:0006413 translational initiation(GO:0006413)
0.0 0.3 GO:0035357 peroxisome proliferator activated receptor signaling pathway(GO:0035357)
0.0 0.2 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.6 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.4 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.7 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.7 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.2 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.0 0.3 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.5 GO:0050714 positive regulation of protein secretion(GO:0050714)
0.0 0.6 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.1 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.0 GO:0045414 regulation of interleukin-8 biosynthetic process(GO:0045414)
0.0 0.3 GO:0044364 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.0 0.1 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0 0.3 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.2 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.8 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.2 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.0 0.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.7 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.1 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.4 GO:0010762 regulation of fibroblast migration(GO:0010762)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:1903095 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.3 0.8 GO:0099631 postsynaptic endocytic zone cytoplasmic component(GO:0099631)
0.2 0.9 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.2 1.6 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.2 1.4 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.2 0.6 GO:0031533 mRNA cap methyltransferase complex(GO:0031533)
0.2 1.5 GO:0005787 signal peptidase complex(GO:0005787)
0.2 0.9 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 1.3 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.4 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 0.8 GO:0000125 PCAF complex(GO:0000125)
0.1 0.4 GO:0071797 LUBAC complex(GO:0071797)
0.1 0.5 GO:0070876 SOSS complex(GO:0070876)
0.1 0.6 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.4 GO:0097441 basilar dendrite(GO:0097441)
0.1 0.5 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 1.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 0.8 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.7 GO:0000813 ESCRT I complex(GO:0000813)
0.1 1.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 1.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.8 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 1.2 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.1 0.7 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.5 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.6 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 0.2 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.1 0.3 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.5 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.3 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 1.6 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.7 GO:0017119 Golgi transport complex(GO:0017119)
0.0 1.0 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.6 GO:0000124 SAGA complex(GO:0000124)
0.0 0.4 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
0.0 0.3 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.4 GO:0000243 commitment complex(GO:0000243)
0.0 0.4 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.8 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.3 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.5 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.8 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.1 GO:0044753 amphisome(GO:0044753)
0.0 0.2 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0034657 GID complex(GO:0034657)
0.0 0.5 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0098888 extrinsic component of presynaptic membrane(GO:0098888)
0.0 0.8 GO:0016592 mediator complex(GO:0016592)
0.0 1.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.4 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.2 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.3 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.8 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.4 GO:0000502 proteasome complex(GO:0000502)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.0 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 1.0 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.0 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.0 0.1 GO:0005869 dynactin complex(GO:0005869)
0.0 0.0 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.2 1.1 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.2 0.6 GO:0004482 mRNA (guanine-N7-)-methyltransferase activity(GO:0004482)
0.2 0.7 GO:0004814 arginine-tRNA ligase activity(GO:0004814) arginine binding(GO:0034618)
0.2 1.6 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.2 0.8 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.1 0.4 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 1.1 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 1.4 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.3 GO:0000992 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.1 1.0 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.5 GO:0034235 GPI anchor binding(GO:0034235)
0.1 0.8 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.9 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.1 0.7 GO:0046790 virion binding(GO:0046790)
0.1 0.5 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.6 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 0.7 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 0.7 GO:1990446 U1 snRNP binding(GO:1990446)
0.1 0.6 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 0.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.8 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.6 GO:0071253 connexin binding(GO:0071253)
0.1 0.6 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 0.8 GO:0015197 peptide transporter activity(GO:0015197)
0.1 0.7 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.4 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 0.2 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 0.3 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 0.7 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 1.0 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.7 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.3 GO:0089720 caspase binding(GO:0089720)
0.0 0.4 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.2 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 0.1 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 1.2 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769)
0.0 0.3 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.6 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 2.5 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.6 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 1.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.1 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.4 GO:0031386 protein tag(GO:0031386)
0.0 0.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 1.3 GO:0043022 ribosome binding(GO:0043022)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 1.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.5 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.7 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 1.6 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.8 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.4 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.3 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.4 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.4 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 2.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.3 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.5 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.2 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.9 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 1.2 PID_IL8_CXCR2_PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.8 PID_ARF_3PATHWAY Arf1 pathway
0.0 0.5 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.5 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 1.5 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.6 PID_MYC_PATHWAY C-MYC pathway
0.0 1.6 PID_LKB1_PATHWAY LKB1 signaling events
0.0 1.0 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 0.7 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 0.6 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.5 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.3 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.0 0.3 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.7 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 0.3 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.5 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 1.5 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 0.8 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 1.1 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 0.7 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 1.7 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.1 2.2 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 0.9 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 1.2 REACTOME_MICRORNA_MIRNA_BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.6 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.2 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.8 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.0 2.5 REACTOME_ER_PHAGOSOME_PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.6 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 1.0 REACTOME_THE_ROLE_OF_NEF_IN_HIV1_REPLICATION_AND_DISEASE_PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.4 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 1.6 REACTOME_SIGNAL_TRANSDUCTION_BY_L1 Genes involved in Signal transduction by L1
0.0 0.7 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.1 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.0 0.5 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 1.2 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.8 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.5 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.4 REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.3 REACTOME_AUTODEGRADATION_OF_CDH1_BY_CDH1_APC_C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0 0.5 REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.1 REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 1.0 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.3 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 1.1 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 0.6 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.3 REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.1 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.2 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 2.6 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.1 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 1.0 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.8 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.4 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.1 REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 1.1 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.1 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.3 REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.3 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 0.7 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport