Motif ID: Alx4
Z-value: 0.567

Transcription factors associated with Alx4:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Alx4 | ENSMUSG00000040310.6 | Alx4 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Alx4 | mm10_v2_chr2_+_93642307_93642388 | -0.14 | 3.9e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 2.7 | GO:0072592 | oxygen metabolic process(GO:0072592) |
0.5 | 1.4 | GO:1904956 | regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041) |
0.4 | 4.0 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
0.3 | 1.0 | GO:0002538 | arachidonic acid metabolite production involved in inflammatory response(GO:0002538) olefin metabolic process(GO:1900673) |
0.3 | 0.8 | GO:0002940 | tRNA N2-guanine methylation(GO:0002940) |
0.3 | 2.1 | GO:1901162 | serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162) |
0.3 | 0.8 | GO:0072204 | cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) |
0.2 | 0.7 | GO:1903054 | negative regulation of extracellular matrix organization(GO:1903054) |
0.2 | 2.0 | GO:0015838 | proline transport(GO:0015824) amino-acid betaine transport(GO:0015838) |
0.2 | 0.4 | GO:0046122 | purine deoxyribonucleoside metabolic process(GO:0046122) |
0.2 | 0.5 | GO:0045819 | plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819) |
0.2 | 0.5 | GO:0046110 | xanthine metabolic process(GO:0046110) |
0.2 | 0.3 | GO:0036518 | chemorepulsion of dopaminergic neuron axon(GO:0036518) |
0.2 | 1.3 | GO:0048625 | myoblast fate commitment(GO:0048625) |
0.2 | 2.1 | GO:0006388 | tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388) |
0.1 | 0.9 | GO:0045743 | positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743) |
0.1 | 2.4 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
0.1 | 0.8 | GO:0002934 | desmosome organization(GO:0002934) |
0.1 | 0.5 | GO:0097211 | response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211) |
0.1 | 1.5 | GO:0051923 | sulfation(GO:0051923) |
0.1 | 0.4 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
0.1 | 0.4 | GO:0061743 | motor learning(GO:0061743) |
0.1 | 0.4 | GO:0097360 | chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382) |
0.1 | 0.5 | GO:1900377 | negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377) |
0.1 | 0.4 | GO:0001920 | negative regulation of receptor recycling(GO:0001920) |
0.1 | 0.8 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
0.1 | 0.4 | GO:0019287 | isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) |
0.1 | 0.4 | GO:0021856 | cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375) |
0.1 | 1.2 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
0.1 | 0.4 | GO:0046208 | spermine catabolic process(GO:0046208) |
0.1 | 0.3 | GO:0006668 | sphinganine-1-phosphate metabolic process(GO:0006668) |
0.1 | 0.3 | GO:0045903 | positive regulation of translational fidelity(GO:0045903) |
0.1 | 0.2 | GO:2000564 | antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187) |
0.1 | 1.8 | GO:0033194 | response to hydroperoxide(GO:0033194) |
0.1 | 0.4 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
0.1 | 0.5 | GO:0019532 | oxalate transport(GO:0019532) |
0.1 | 0.3 | GO:0015788 | UDP-N-acetylglucosamine transport(GO:0015788) |
0.1 | 0.4 | GO:0043504 | mitochondrial DNA repair(GO:0043504) |
0.1 | 0.6 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
0.1 | 0.4 | GO:1902035 | positive regulation of hematopoietic stem cell proliferation(GO:1902035) |
0.1 | 0.7 | GO:0045607 | regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980) |
0.1 | 0.1 | GO:0021886 | hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888) |
0.1 | 0.6 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
0.1 | 0.8 | GO:0030497 | fatty acid elongation(GO:0030497) |
0.1 | 0.2 | GO:0010749 | regulation of nitric oxide mediated signal transduction(GO:0010749) |
0.1 | 1.3 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
0.1 | 0.9 | GO:2000353 | positive regulation of endothelial cell apoptotic process(GO:2000353) |
0.1 | 1.8 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
0.1 | 0.2 | GO:1901727 | positive regulation of histone deacetylase activity(GO:1901727) |
0.0 | 0.4 | GO:0006348 | chromatin silencing at telomere(GO:0006348) |
0.0 | 0.5 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
0.0 | 0.4 | GO:1900262 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
0.0 | 0.5 | GO:0006228 | UTP biosynthetic process(GO:0006228) |
0.0 | 0.3 | GO:0072615 | interleukin-17 secretion(GO:0072615) |
0.0 | 1.3 | GO:0071384 | cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385) |
0.0 | 0.6 | GO:0003215 | cardiac right ventricle morphogenesis(GO:0003215) |
0.0 | 2.3 | GO:0022904 | respiratory electron transport chain(GO:0022904) |
0.0 | 0.5 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
0.0 | 0.4 | GO:0000712 | resolution of meiotic recombination intermediates(GO:0000712) |
0.0 | 0.6 | GO:0032331 | negative regulation of chondrocyte differentiation(GO:0032331) |
0.0 | 0.2 | GO:0052695 | cellular glucuronidation(GO:0052695) |
0.0 | 1.0 | GO:0031365 | N-terminal protein amino acid modification(GO:0031365) |
0.0 | 1.9 | GO:0030500 | regulation of bone mineralization(GO:0030500) |
0.0 | 0.1 | GO:0006742 | NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364) |
0.0 | 0.5 | GO:0035493 | SNARE complex assembly(GO:0035493) |
0.0 | 0.2 | GO:0060770 | negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) |
0.0 | 0.2 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
0.0 | 0.3 | GO:2000580 | positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582) |
0.0 | 0.4 | GO:0060707 | trophoblast giant cell differentiation(GO:0060707) |
0.0 | 0.1 | GO:1902741 | type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741) |
0.0 | 0.6 | GO:0006907 | pinocytosis(GO:0006907) |
0.0 | 0.5 | GO:0018126 | protein hydroxylation(GO:0018126) |
0.0 | 0.3 | GO:1903504 | regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504) |
0.0 | 0.2 | GO:0048096 | chromatin-mediated maintenance of transcription(GO:0048096) |
0.0 | 0.3 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
0.0 | 1.0 | GO:0006418 | tRNA aminoacylation for protein translation(GO:0006418) |
0.0 | 0.5 | GO:0045026 | plasma membrane fusion(GO:0045026) |
0.0 | 0.2 | GO:0061635 | regulation of protein complex stability(GO:0061635) |
0.0 | 0.1 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) |
0.0 | 0.1 | GO:0042360 | vitamin E metabolic process(GO:0042360) |
0.0 | 0.4 | GO:0003417 | growth plate cartilage development(GO:0003417) |
0.0 | 0.4 | GO:0051764 | actin crosslink formation(GO:0051764) |
0.0 | 0.2 | GO:0042572 | retinol metabolic process(GO:0042572) |
0.0 | 0.9 | GO:0051693 | actin filament capping(GO:0051693) |
0.0 | 0.2 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
0.0 | 0.1 | GO:1903690 | negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
0.0 | 0.2 | GO:1902416 | positive regulation of mRNA binding(GO:1902416) |
0.0 | 0.7 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
0.0 | 0.0 | GO:1902605 | heterotrimeric G-protein complex assembly(GO:1902605) |
0.0 | 0.3 | GO:0048240 | sperm capacitation(GO:0048240) |
0.0 | 0.2 | GO:0045579 | positive regulation of B cell differentiation(GO:0045579) |
0.0 | 0.4 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.0 | 0.1 | GO:0042420 | dopamine catabolic process(GO:0042420) |
0.0 | 0.3 | GO:0002183 | cytoplasmic translational initiation(GO:0002183) |
0.0 | 0.2 | GO:1902916 | positive regulation of protein polyubiquitination(GO:1902916) |
0.0 | 0.0 | GO:1902498 | regulation of protein K63-linked ubiquitination(GO:1900044) regulation of protein autoubiquitination(GO:1902498) |
0.0 | 0.2 | GO:0006953 | acute-phase response(GO:0006953) |
0.0 | 0.1 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
0.0 | 0.1 | GO:0021555 | midbrain-hindbrain boundary morphogenesis(GO:0021555) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 2.1 | GO:0002111 | BRCA2-BRAF35 complex(GO:0002111) |
0.4 | 1.5 | GO:0071438 | invadopodium membrane(GO:0071438) |
0.4 | 1.1 | GO:0042585 | germinal vesicle(GO:0042585) |
0.1 | 1.3 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) |
0.1 | 2.6 | GO:0098644 | complex of collagen trimers(GO:0098644) |
0.1 | 0.5 | GO:0045251 | mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251) |
0.1 | 1.0 | GO:0016272 | prefoldin complex(GO:0016272) |
0.1 | 0.5 | GO:0070820 | tertiary granule(GO:0070820) |
0.1 | 0.4 | GO:0005594 | collagen type IX trimer(GO:0005594) |
0.1 | 0.6 | GO:0097422 | tubular endosome(GO:0097422) |
0.1 | 0.4 | GO:0044301 | climbing fiber(GO:0044301) |
0.1 | 6.1 | GO:0070469 | respiratory chain(GO:0070469) |
0.1 | 0.5 | GO:0005687 | U4 snRNP(GO:0005687) |
0.1 | 0.3 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
0.1 | 0.4 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
0.1 | 0.4 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
0.1 | 1.3 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
0.1 | 0.7 | GO:0031258 | lamellipodium membrane(GO:0031258) |
0.1 | 0.5 | GO:0034709 | methylosome(GO:0034709) |
0.0 | 0.4 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
0.0 | 0.5 | GO:0042555 | MCM complex(GO:0042555) |
0.0 | 1.7 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
0.0 | 0.3 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
0.0 | 0.3 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
0.0 | 0.9 | GO:0005581 | collagen trimer(GO:0005581) |
0.0 | 0.3 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
0.0 | 0.2 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
0.0 | 0.2 | GO:0042612 | MHC class I protein complex(GO:0042612) |
0.0 | 1.3 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
0.0 | 4.2 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
0.0 | 0.2 | GO:0030127 | COPII vesicle coat(GO:0030127) |
0.0 | 0.4 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
0.0 | 0.5 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
0.0 | 0.1 | GO:0000942 | condensed nuclear chromosome outer kinetochore(GO:0000942) |
0.0 | 0.1 | GO:0097413 | Lewy body(GO:0097413) |
0.0 | 0.8 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
0.0 | 0.2 | GO:0043231 | intracellular membrane-bounded organelle(GO:0043231) |
0.0 | 2.6 | GO:0005802 | trans-Golgi network(GO:0005802) |
0.0 | 0.1 | GO:0020005 | symbiont-containing vacuole membrane(GO:0020005) |
0.0 | 0.6 | GO:0045171 | intercellular bridge(GO:0045171) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 2.1 | GO:0004510 | tryptophan 5-monooxygenase activity(GO:0004510) |
0.5 | 1.5 | GO:0030171 | voltage-gated proton channel activity(GO:0030171) |
0.5 | 1.5 | GO:0050656 | 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656) |
0.4 | 2.1 | GO:0000213 | tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892) |
0.3 | 1.6 | GO:0019770 | IgG receptor activity(GO:0019770) |
0.3 | 0.8 | GO:0019166 | trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166) |
0.2 | 2.0 | GO:0015193 | L-proline transmembrane transporter activity(GO:0015193) |
0.2 | 1.0 | GO:0004301 | epoxide hydrolase activity(GO:0004301) |
0.2 | 1.2 | GO:1990932 | 5.8S rRNA binding(GO:1990932) |
0.2 | 0.5 | GO:0000402 | open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402) |
0.2 | 4.8 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.2 | 0.8 | GO:0004809 | tRNA (guanine-N2-)-methyltransferase activity(GO:0004809) |
0.1 | 0.5 | GO:0030151 | molybdenum ion binding(GO:0030151) |
0.1 | 0.4 | GO:0046592 | polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901) |
0.1 | 2.1 | GO:0000400 | four-way junction DNA binding(GO:0000400) |
0.1 | 0.3 | GO:0052740 | phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740) |
0.1 | 1.3 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
0.1 | 0.5 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
0.1 | 0.4 | GO:0019136 | deoxynucleoside kinase activity(GO:0019136) |
0.1 | 0.3 | GO:0036470 | tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478) |
0.1 | 0.6 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
0.1 | 0.4 | GO:0034235 | GPI anchor binding(GO:0034235) |
0.1 | 0.6 | GO:0034452 | dynactin binding(GO:0034452) |
0.1 | 0.4 | GO:0008297 | single-stranded DNA exodeoxyribonuclease activity(GO:0008297) |
0.1 | 1.6 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.1 | 1.7 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.1 | 0.3 | GO:0008142 | oxysterol binding(GO:0008142) |
0.1 | 3.8 | GO:0050840 | extracellular matrix binding(GO:0050840) |
0.1 | 0.9 | GO:0002161 | aminoacyl-tRNA editing activity(GO:0002161) |
0.1 | 0.8 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
0.1 | 1.3 | GO:0070016 | gamma-catenin binding(GO:0045295) armadillo repeat domain binding(GO:0070016) |
0.1 | 0.5 | GO:1990446 | U1 snRNP binding(GO:1990446) |
0.1 | 0.8 | GO:0008484 | sulfuric ester hydrolase activity(GO:0008484) |
0.1 | 1.9 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
0.0 | 0.4 | GO:0001025 | RNA polymerase III transcription factor binding(GO:0001025) |
0.0 | 0.5 | GO:0019531 | secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531) |
0.0 | 0.4 | GO:0038191 | neuropilin binding(GO:0038191) |
0.0 | 0.4 | GO:0042609 | CD4 receptor binding(GO:0042609) |
0.0 | 0.4 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
0.0 | 0.4 | GO:0050308 | sugar-phosphatase activity(GO:0050308) |
0.0 | 0.5 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
0.0 | 0.9 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
0.0 | 0.9 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
0.0 | 1.3 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) |
0.0 | 0.1 | GO:0035529 | NADH pyrophosphatase activity(GO:0035529) |
0.0 | 0.2 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
0.0 | 0.4 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
0.0 | 0.5 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
0.0 | 0.4 | GO:0010485 | H4 histone acetyltransferase activity(GO:0010485) |
0.0 | 0.1 | GO:0008384 | IkappaB kinase activity(GO:0008384) |
0.0 | 0.2 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
0.0 | 0.7 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
0.0 | 0.4 | GO:0051400 | BH domain binding(GO:0051400) |
0.0 | 0.9 | GO:0031369 | translation initiation factor binding(GO:0031369) |
0.0 | 0.4 | GO:0008188 | neuropeptide receptor activity(GO:0008188) |
0.0 | 0.8 | GO:0005484 | SNAP receptor activity(GO:0005484) |
0.0 | 0.6 | GO:0005109 | frizzled binding(GO:0005109) |
0.0 | 0.5 | GO:0009055 | electron carrier activity(GO:0009055) |
0.0 | 1.5 | GO:0008276 | protein methyltransferase activity(GO:0008276) |
0.0 | 0.4 | GO:0008327 | methyl-CpG binding(GO:0008327) |
0.0 | 0.2 | GO:1990715 | mRNA CDS binding(GO:1990715) |
0.0 | 1.1 | GO:0005080 | protein kinase C binding(GO:0005080) |
0.0 | 0.2 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
0.0 | 0.6 | GO:0042169 | SH2 domain binding(GO:0042169) |
0.0 | 0.4 | GO:0005402 | cation:sugar symporter activity(GO:0005402) |
0.0 | 0.1 | GO:0051378 | primary amine oxidase activity(GO:0008131) serotonin binding(GO:0051378) |
0.0 | 0.7 | GO:0005518 | collagen binding(GO:0005518) |
0.0 | 0.1 | GO:0005113 | patched binding(GO:0005113) cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
0.0 | 0.6 | GO:0046983 | protein dimerization activity(GO:0046983) |
0.0 | 0.5 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
0.0 | 0.0 | GO:0004816 | asparagine-tRNA ligase activity(GO:0004816) |
0.0 | 0.1 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
0.0 | 0.4 | GO:0016776 | phosphotransferase activity, phosphate group as acceptor(GO:0016776) |
0.0 | 0.2 | GO:0005044 | scavenger receptor activity(GO:0005044) |
0.0 | 0.2 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
0.0 | 0.4 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
0.0 | 1.0 | GO:0051082 | unfolded protein binding(GO:0051082) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 4.5 | PID_FRA_PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
0.1 | 2.0 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
0.0 | 0.7 | PID_ANTHRAX_PATHWAY | Cellular roles of Anthrax toxin |
0.0 | 1.3 | NABA_COLLAGENS | Genes encoding collagen proteins |
0.0 | 1.4 | ST_WNT_BETA_CATENIN_PATHWAY | Wnt/beta-catenin Pathway |
0.0 | 1.5 | PID_RAC1_PATHWAY | RAC1 signaling pathway |
0.0 | 1.3 | PID_AP1_PATHWAY | AP-1 transcription factor network |
0.0 | 0.9 | PID_ATR_PATHWAY | ATR signaling pathway |
0.0 | 0.8 | PID_DELTA_NP63_PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
0.0 | 0.5 | PID_ALPHA_SYNUCLEIN_PATHWAY | Alpha-synuclein signaling |
0.0 | 0.3 | PID_S1P_META_PATHWAY | Sphingosine 1-phosphate (S1P) pathway |
0.0 | 0.8 | PID_AJDISS_2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
0.0 | 0.9 | PID_P73PATHWAY | p73 transcription factor network |
0.0 | 0.4 | PID_ARF6_PATHWAY | Arf6 signaling events |
0.0 | 0.2 | PID_MYC_PATHWAY | C-MYC pathway |
0.0 | 0.3 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
0.0 | 0.4 | ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY | PI3K Pathway |
0.0 | 0.9 | WNT_SIGNALING | Genes related to Wnt-mediated signal transduction |
0.0 | 0.4 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
0.0 | 1.4 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.0 | 0.6 | PID_P53_REGULATION_PATHWAY | p53 pathway |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 4.0 | REACTOME_CS_DS_DEGRADATION | Genes involved in CS/DS degradation |
0.2 | 1.5 | REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
0.2 | 2.1 | REACTOME_AMINE_DERIVED_HORMONES | Genes involved in Amine-derived hormones |
0.1 | 1.1 | REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
0.1 | 0.8 | REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
0.1 | 0.8 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
0.0 | 1.1 | REACTOME_TRAF6_MEDIATED_NFKB_ACTIVATION | Genes involved in TRAF6 mediated NF-kB activation |
0.0 | 0.4 | REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION | Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation |
0.0 | 1.0 | REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
0.0 | 0.5 | REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
0.0 | 0.7 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
0.0 | 0.5 | REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
0.0 | 1.7 | REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
0.0 | 0.4 | REACTOME_POL_SWITCHING | Genes involved in Polymerase switching |
0.0 | 1.0 | REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |
0.0 | 0.5 | REACTOME_UNWINDING_OF_DNA | Genes involved in Unwinding of DNA |
0.0 | 0.3 | REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE | Genes involved in mRNA Decay by 3' to 5' Exoribonuclease |
0.0 | 0.4 | REACTOME_METABOLISM_OF_POLYAMINES | Genes involved in Metabolism of polyamines |
0.0 | 0.4 | REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
0.0 | 0.4 | REACTOME_PURINE_SALVAGE | Genes involved in Purine salvage |
0.0 | 0.4 | REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION | Genes involved in Sema3A PAK dependent Axon repulsion |
0.0 | 0.2 | REACTOME_GLUCURONIDATION | Genes involved in Glucuronidation |
0.0 | 0.4 | REACTOME_CHOLESTEROL_BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
0.0 | 1.0 | REACTOME_PEPTIDE_CHAIN_ELONGATION | Genes involved in Peptide chain elongation |
0.0 | 0.8 | REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
0.0 | 0.3 | REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
0.0 | 1.8 | REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
0.0 | 0.3 | REACTOME_G0_AND_EARLY_G1 | Genes involved in G0 and Early G1 |
0.0 | 0.2 | REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
0.0 | 0.8 | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT | Genes involved in Respiratory electron transport |
0.0 | 0.4 | REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS | Genes involved in Post-translational modification: synthesis of GPI-anchored proteins |
0.0 | 0.1 | REACTOME_PURINE_CATABOLISM | Genes involved in Purine catabolism |