Motif ID: Id4

Z-value: 0.989


Transcription factors associated with Id4:

Gene SymbolEntrez IDGene Name
Id4 ENSMUSG00000021379.1 Id4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Id4mm10_v2_chr13_+_48261427_482614270.221.7e-01Click!


Activity profile for motif Id4.

activity profile for motif Id4


Sorted Z-values histogram for motif Id4

Sorted Z-values for motif Id4



Network of associatons between targets according to the STRING database.



First level regulatory network of Id4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_70562007 5.272 ENSMUST00000094934.4
Gad1
glutamate decarboxylase 1
chr3_-_82145865 4.862 ENSMUST00000048976.6
Gucy1a3
guanylate cyclase 1, soluble, alpha 3
chr2_+_70562147 4.802 ENSMUST00000148210.1
Gad1
glutamate decarboxylase 1
chr14_-_103843685 4.741 ENSMUST00000172237.1
Ednrb
endothelin receptor type B
chr11_-_67922136 4.459 ENSMUST00000021288.3
ENSMUST00000108677.1
Usp43

ubiquitin specific peptidase 43

chr15_-_66831625 4.409 ENSMUST00000164163.1
Sla
src-like adaptor
chr16_+_91269759 4.314 ENSMUST00000056882.5
Olig1
oligodendrocyte transcription factor 1
chr19_+_36409719 4.057 ENSMUST00000062389.5
Pcgf5
polycomb group ring finger 5
chr3_+_145758674 3.907 ENSMUST00000029845.8
Ddah1
dimethylarginine dimethylaminohydrolase 1
chr17_-_25570678 3.689 ENSMUST00000025003.3
ENSMUST00000173447.1
Sox8

SRY-box containing gene 8

chr15_-_98677451 3.669 ENSMUST00000120997.1
ENSMUST00000109149.2
ENSMUST00000003451.4
Rnd1


Rho family GTPase 1


chr4_+_125490688 3.536 ENSMUST00000030676.7
Grik3
glutamate receptor, ionotropic, kainate 3
chr14_-_103844173 3.499 ENSMUST00000022718.3
Ednrb
endothelin receptor type B
chr8_-_4217133 3.471 ENSMUST00000175906.1
BC068157
cDNA sequence BC068157
chr4_-_137766474 2.963 ENSMUST00000139951.1
Alpl
alkaline phosphatase, liver/bone/kidney
chr1_+_86045863 2.897 ENSMUST00000165824.1
2810459M11Rik
RIKEN cDNA 2810459M11 gene
chr3_+_89436736 2.859 ENSMUST00000146630.1
ENSMUST00000145753.1
Pbxip1

pre B cell leukemia transcription factor interacting protein 1

chr15_-_98004634 2.848 ENSMUST00000131560.1
ENSMUST00000088355.5
Col2a1

collagen, type II, alpha 1

chr8_-_4217459 2.810 ENSMUST00000176227.1
BC068157
cDNA sequence BC068157
chr7_+_126847908 2.805 ENSMUST00000147257.1
ENSMUST00000139174.1
Doc2a

double C2, alpha

chr12_-_91779129 2.760 ENSMUST00000170077.1
Ston2
stonin 2
chr12_+_3806513 2.737 ENSMUST00000172719.1
Dnmt3a
DNA methyltransferase 3A
chr11_+_115163333 2.722 ENSMUST00000021077.3
Slc9a3r1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr15_-_98004695 2.679 ENSMUST00000023123.8
Col2a1
collagen, type II, alpha 1
chr3_+_89436699 2.606 ENSMUST00000038942.3
ENSMUST00000130858.1
Pbxip1

pre B cell leukemia transcription factor interacting protein 1

chr8_-_70439557 2.599 ENSMUST00000076615.5
Crtc1
CREB regulated transcription coactivator 1
chr4_-_137796350 2.587 ENSMUST00000030551.4
Alpl
alkaline phosphatase, liver/bone/kidney
chr6_+_17307272 2.394 ENSMUST00000115454.1
Cav1
caveolin 1, caveolae protein
chr8_-_4216912 2.351 ENSMUST00000177491.1
BC068157
cDNA sequence BC068157
chr7_-_116308241 2.348 ENSMUST00000183057.1
ENSMUST00000182487.1
ENSMUST00000181998.1
Plekha7


pleckstrin homology domain containing, family A member 7


chrX_+_100730178 2.329 ENSMUST00000113744.1
Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr2_+_163225363 2.319 ENSMUST00000099110.3
ENSMUST00000165937.1
Tox2

TOX high mobility group box family member 2

chr1_-_119053339 2.318 ENSMUST00000161301.1
ENSMUST00000161451.1
ENSMUST00000162607.1
Gli2


GLI-Kruppel family member GLI2


chr10_-_127341583 2.299 ENSMUST00000026474.3
Gli1
GLI-Kruppel family member GLI1
chr10_-_58675631 2.234 ENSMUST00000003312.4
Edar
ectodysplasin-A receptor
chr2_-_93334467 2.217 ENSMUST00000111265.2
Tspan18
tetraspanin 18
chr9_+_44134562 2.194 ENSMUST00000034650.8
ENSMUST00000098852.2
Mcam

melanoma cell adhesion molecule

chr9_+_35423582 2.151 ENSMUST00000154652.1
Cdon
cell adhesion molecule-related/down-regulated by oncogenes
chr9_-_108263887 2.088 ENSMUST00000166905.1
ENSMUST00000080435.2
Dag1

dystroglycan 1

chr7_-_25250720 2.026 ENSMUST00000116343.2
ENSMUST00000045847.8
Erf

Ets2 repressor factor

chr9_-_108263706 2.005 ENSMUST00000171412.1
Dag1
dystroglycan 1
chr5_-_67847360 1.976 ENSMUST00000072971.6
Atp8a1
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
chr6_+_17307632 1.967 ENSMUST00000115453.1
Cav1
caveolin 1, caveolae protein
chr2_-_52335134 1.951 ENSMUST00000075301.3
Neb
nebulin
chr2_+_19909769 1.931 ENSMUST00000114610.1
Etl4
enhancer trap locus 4
chr2_-_122611238 1.909 ENSMUST00000028624.8
Gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr13_-_60177357 1.902 ENSMUST00000065086.4
Gas1
growth arrest specific 1
chr7_-_25788635 1.885 ENSMUST00000002677.4
ENSMUST00000085948.4
Axl

AXL receptor tyrosine kinase

chr15_-_71727815 1.879 ENSMUST00000022953.8
Fam135b
family with sequence similarity 135, member B
chr14_-_62292959 1.867 ENSMUST00000063169.8
Dleu7
deleted in lymphocytic leukemia, 7
chr7_+_130936172 1.859 ENSMUST00000006367.7
Htra1
HtrA serine peptidase 1
chr11_+_117809653 1.791 ENSMUST00000026649.7
ENSMUST00000177131.1
ENSMUST00000132298.1
Syngr2

Gm20708
synaptogyrin 2

predicted gene 20708
chr7_-_66427469 1.786 ENSMUST00000015278.7
Aldh1a3
aldehyde dehydrogenase family 1, subfamily A3
chr16_+_13256481 1.726 ENSMUST00000009713.7
ENSMUST00000115809.1
Mkl2

MKL/myocardin-like 2

chr14_+_31019183 1.718 ENSMUST00000052239.5
Pbrm1
polybromo 1
chr2_+_130406478 1.709 ENSMUST00000055421.4
Tmem239
transmembrane 239
chr7_-_89517576 1.707 ENSMUST00000041761.5
Prss23
protease, serine, 23
chr11_+_42419729 1.700 ENSMUST00000007797.4
Gabrb2
gamma-aminobutyric acid (GABA) A receptor, subunit beta 2
chr5_-_135251209 1.700 ENSMUST00000062572.2
Fzd9
frizzled homolog 9 (Drosophila)
chr3_-_84305385 1.685 ENSMUST00000122849.1
ENSMUST00000132283.1
Trim2

tripartite motif-containing 2

chr14_+_27039001 1.676 ENSMUST00000035336.3
Il17rd
interleukin 17 receptor D
chr8_+_15011025 1.667 ENSMUST00000069399.6
Kbtbd11
kelch repeat and BTB (POZ) domain containing 11
chr9_-_48911067 1.662 ENSMUST00000003826.7
Htr3a
5-hydroxytryptamine (serotonin) receptor 3A
chr15_-_72034202 1.654 ENSMUST00000159993.1
Col22a1
collagen, type XXII, alpha 1
chr19_-_3686549 1.650 ENSMUST00000025856.10
ENSMUST00000176867.1
Lrp5

low density lipoprotein receptor-related protein 5

chr19_-_36736653 1.539 ENSMUST00000087321.2
Ppp1r3c
protein phosphatase 1, regulatory (inhibitor) subunit 3C
chr1_-_153332724 1.537 ENSMUST00000027752.8
Lamc1
laminin, gamma 1
chr19_-_24555819 1.511 ENSMUST00000112673.2
ENSMUST00000025800.8
Pip5k1b

phosphatidylinositol-4-phosphate 5-kinase, type 1 beta

chr3_+_121723515 1.500 ENSMUST00000029771.8
F3
coagulation factor III
chr1_+_87327044 1.495 ENSMUST00000173173.1
Gigyf2
GRB10 interacting GYF protein 2
chr18_-_32559914 1.486 ENSMUST00000174000.1
ENSMUST00000174459.1
Gypc

glycophorin C

chr5_+_66745835 1.482 ENSMUST00000101164.4
ENSMUST00000118242.1
ENSMUST00000119854.1
ENSMUST00000117601.1
Limch1



LIM and calponin homology domains 1



chr9_-_95845215 1.474 ENSMUST00000093800.2
Pls1
plastin 1 (I-isoform)
chr7_+_25282784 1.469 ENSMUST00000165239.1
Cic
capicua homolog (Drosophila)
chr1_-_64737735 1.444 ENSMUST00000063982.5
ENSMUST00000116133.2
Fzd5

frizzled homolog 5 (Drosophila)

chr7_+_19094594 1.438 ENSMUST00000049454.5
Six5
sine oculis-related homeobox 5
chr11_+_68692070 1.421 ENSMUST00000108673.1
Myh10
myosin, heavy polypeptide 10, non-muscle
chr7_+_126862431 1.418 ENSMUST00000132808.1
Hirip3
HIRA interacting protein 3
chr1_+_61638819 1.417 ENSMUST00000138768.1
ENSMUST00000075374.3
Pard3b

par-3 partitioning defective 3 homolog B (C. elegans)

chr15_+_25622525 1.415 ENSMUST00000110457.1
ENSMUST00000137601.1
Myo10

myosin X

chr6_+_4902913 1.408 ENSMUST00000175889.1
ENSMUST00000168998.2
Ppp1r9a

protein phosphatase 1, regulatory (inhibitor) subunit 9A

chr3_+_137623672 1.406 ENSMUST00000053855.7
Ddit4l
DNA-damage-inducible transcript 4-like
chr9_+_30942541 1.405 ENSMUST00000068135.6
Adamts8
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8
chr17_-_51831884 1.398 ENSMUST00000124222.1
Satb1
special AT-rich sequence binding protein 1
chr10_-_81407641 1.376 ENSMUST00000140916.1
Nfic
nuclear factor I/C
chr8_+_70493156 1.371 ENSMUST00000008032.7
Crlf1
cytokine receptor-like factor 1
chr14_+_31019159 1.344 ENSMUST00000112094.1
ENSMUST00000144009.1
Pbrm1

polybromo 1

chr6_+_17307040 1.318 ENSMUST00000123439.1
Cav1
caveolin 1, caveolae protein
chr10_+_81257277 1.314 ENSMUST00000117488.1
ENSMUST00000105328.3
ENSMUST00000121205.1
Matk


megakaryocyte-associated tyrosine kinase


chr10_+_89873497 1.309 ENSMUST00000183156.1
ENSMUST00000182936.1
ENSMUST00000099368.4
Anks1b


ankyrin repeat and sterile alpha motif domain containing 1B


chr12_-_76709997 1.304 ENSMUST00000166101.1
Sptb
spectrin beta, erythrocytic
chr7_-_80401707 1.296 ENSMUST00000120753.1
Furin
furin (paired basic amino acid cleaving enzyme)
chr12_+_82616885 1.280 ENSMUST00000161801.1
Rgs6
regulator of G-protein signaling 6
chr8_+_12873793 1.264 ENSMUST00000156560.1
ENSMUST00000095456.3
Mcf2l

mcf.2 transforming sequence-like

chr8_-_13677575 1.261 ENSMUST00000117551.2
Rasa3
RAS p21 protein activator 3
chr2_+_62664279 1.259 ENSMUST00000028257.2
Gca
grancalcin
chr5_+_37028329 1.247 ENSMUST00000173836.1
Jakmip1
janus kinase and microtubule interacting protein 1
chr11_+_63128973 1.246 ENSMUST00000108702.1
Pmp22
peripheral myelin protein 22
chr15_-_37791993 1.243 ENSMUST00000168992.1
ENSMUST00000148652.1
Ncald

neurocalcin delta

chr19_+_16435616 1.224 ENSMUST00000025602.2
Gna14
guanine nucleotide binding protein, alpha 14
chr7_-_46099752 1.224 ENSMUST00000180081.1
Kcnj11
potassium inwardly rectifying channel, subfamily J, member 11
chr18_+_60925612 1.222 ENSMUST00000102888.3
ENSMUST00000025519.4
Camk2a

calcium/calmodulin-dependent protein kinase II alpha

chr1_+_87403705 1.213 ENSMUST00000172736.1
Gigyf2
GRB10 interacting GYF protein 2
chr4_+_104367549 1.212 ENSMUST00000106830.2
Dab1
disabled 1
chr12_+_85473883 1.206 ENSMUST00000021674.6
Fos
FBJ osteosarcoma oncogene
chr4_+_58943575 1.204 ENSMUST00000107554.1
Zkscan16
zinc finger with KRAB and SCAN domains 16
chr16_+_11984581 1.204 ENSMUST00000170672.2
ENSMUST00000023138.7
Shisa9

shisa homolog 9 (Xenopus laevis)

chr14_-_30353468 1.202 ENSMUST00000112249.1
Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr5_-_67847400 1.188 ENSMUST00000113652.1
ENSMUST00000113651.1
ENSMUST00000037380.8
Atp8a1


ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1


chr9_+_80165079 1.184 ENSMUST00000184480.1
Myo6
myosin VI
chr8_+_120537423 1.182 ENSMUST00000118136.1
Gse1
genetic suppressor element 1
chr14_+_64652524 1.182 ENSMUST00000100473.4
Kif13b
kinesin family member 13B
chr17_+_32036098 1.178 ENSMUST00000081339.6
Rrp1b
ribosomal RNA processing 1 homolog B (S. cerevisiae)
chr7_-_131410325 1.177 ENSMUST00000154602.1
Ikzf5
IKAROS family zinc finger 5
chr1_+_165788681 1.173 ENSMUST00000161971.1
ENSMUST00000178336.1
ENSMUST00000005907.5
ENSMUST00000027849.4
Cd247



CD247 antigen



chr13_+_83504032 1.169 ENSMUST00000163888.1
ENSMUST00000005722.7
Mef2c

myocyte enhancer factor 2C

chr19_-_40271506 1.168 ENSMUST00000068439.6
Pdlim1
PDZ and LIM domain 1 (elfin)
chr6_+_29433248 1.158 ENSMUST00000101617.2
ENSMUST00000065090.5
Flnc

filamin C, gamma

chr12_+_81026800 1.148 ENSMUST00000110347.2
ENSMUST00000021564.4
ENSMUST00000129362.1
Smoc1


SPARC related modular calcium binding 1


chr19_+_5740885 1.137 ENSMUST00000081496.5
Ltbp3
latent transforming growth factor beta binding protein 3
chr11_+_19924403 1.123 ENSMUST00000093298.5
Spred2
sprouty-related, EVH1 domain containing 2
chr11_+_53519871 1.123 ENSMUST00000120878.2
Sept8
septin 8
chr7_-_27337667 1.121 ENSMUST00000038618.6
ENSMUST00000108369.2
Ltbp4

latent transforming growth factor beta binding protein 4

chr11_-_5152218 1.117 ENSMUST00000163299.1
ENSMUST00000062821.6
Emid1

EMI domain containing 1

chr1_+_87327008 1.111 ENSMUST00000172794.1
ENSMUST00000164992.2
Gigyf2

GRB10 interacting GYF protein 2

chr2_+_112265809 1.111 ENSMUST00000110991.2
Slc12a6
solute carrier family 12, member 6
chr7_-_29505447 1.110 ENSMUST00000183096.1
ENSMUST00000085809.4
Sipa1l3

signal-induced proliferation-associated 1 like 3

chr11_-_51756378 1.106 ENSMUST00000109092.1
ENSMUST00000064297.4
ENSMUST00000109097.2
Sec24a


Sec24 related gene family, member A (S. cerevisiae)


chr4_+_136172367 1.103 ENSMUST00000061721.5
E2f2
E2F transcription factor 2
chr16_-_34263179 1.093 ENSMUST00000114949.1
ENSMUST00000114954.1
Kalrn

kalirin, RhoGEF kinase

chr11_+_117809687 1.091 ENSMUST00000120928.1
ENSMUST00000175737.1
Syngr2

synaptogyrin 2

chr1_-_128103016 1.083 ENSMUST00000097597.2
Zranb3
zinc finger, RAN-binding domain containing 3
chr6_-_37299950 1.078 ENSMUST00000101532.3
Dgki
diacylglycerol kinase, iota
chr1_-_119648903 1.076 ENSMUST00000163147.1
ENSMUST00000052404.6
ENSMUST00000027632.7
Epb4.1l5


erythrocyte protein band 4.1-like 5


chr15_+_39006272 1.075 ENSMUST00000179165.1
ENSMUST00000022906.7
Fzd6

frizzled homolog 6 (Drosophila)

chr11_+_53519920 1.071 ENSMUST00000147912.1
Sept8
septin 8
chr15_-_99875382 1.065 ENSMUST00000073691.3
Lima1
LIM domain and actin binding 1
chr5_+_64812336 1.059 ENSMUST00000166409.1
Klf3
Kruppel-like factor 3 (basic)
chr11_+_61956779 1.058 ENSMUST00000049836.7
Specc1
sperm antigen with calponin homology and coiled-coil domains 1
chr10_+_24223517 1.045 ENSMUST00000095784.2
Moxd1
monooxygenase, DBH-like 1
chr19_-_50678485 1.042 ENSMUST00000111756.3
Sorcs1
VPS10 domain receptor protein SORCS 1
chr3_+_40800778 1.032 ENSMUST00000169566.1
Plk4
polo-like kinase 4
chr12_-_4592927 1.029 ENSMUST00000170816.1
Gm3625
predicted gene 3625
chr2_-_26092149 1.018 ENSMUST00000114159.2
Nacc2
nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
chr4_+_102087543 1.016 ENSMUST00000106911.1
Pde4b
phosphodiesterase 4B, cAMP specific
chr14_+_54936456 1.005 ENSMUST00000037814.6
Cmtm5
CKLF-like MARVEL transmembrane domain containing 5
chr18_+_77185979 1.003 ENSMUST00000075290.6
St8sia5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr7_-_116031047 1.002 ENSMUST00000106612.1
Sox6
SRY-box containing gene 6
chr7_-_14562171 1.002 ENSMUST00000181796.1
Vmn1r90
vomeronasal 1 receptor 90
chr19_-_50678642 0.996 ENSMUST00000072685.6
ENSMUST00000164039.2
Sorcs1

VPS10 domain receptor protein SORCS 1

chr5_+_123749696 0.993 ENSMUST00000031366.7
Kntc1
kinetochore associated 1
chr4_+_62583568 0.987 ENSMUST00000098031.3
Rgs3
regulator of G-protein signaling 3
chr14_+_101840602 0.972 ENSMUST00000159314.1
Lmo7
LIM domain only 7
chr7_+_4137475 0.972 ENSMUST00000154571.1
Leng8
leukocyte receptor cluster (LRC) member 8
chr5_-_5266038 0.969 ENSMUST00000115451.1
ENSMUST00000115452.1
ENSMUST00000131392.1
Cdk14


cyclin-dependent kinase 14


chr1_+_132008285 0.967 ENSMUST00000146432.1
Elk4
ELK4, member of ETS oncogene family
chr11_+_16257706 0.960 ENSMUST00000109645.2
ENSMUST00000109647.2
Vstm2a

V-set and transmembrane domain containing 2A

chr11_+_68432112 0.958 ENSMUST00000021283.7
Pik3r5
phosphoinositide-3-kinase, regulatory subunit 5, p101
chr1_+_165788746 0.958 ENSMUST00000161559.2
Cd247
CD247 antigen
chr12_+_108334341 0.957 ENSMUST00000021684.4
Cyp46a1
cytochrome P450, family 46, subfamily a, polypeptide 1
chr5_+_32136458 0.955 ENSMUST00000031017.9
Fosl2
fos-like antigen 2
chr4_+_53440388 0.955 ENSMUST00000102911.3
ENSMUST00000107646.2
Slc44a1

solute carrier family 44, member 1

chr11_-_109473598 0.954 ENSMUST00000070152.5
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr1_-_164458345 0.954 ENSMUST00000027863.7
Atp1b1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr11_-_97280332 0.954 ENSMUST00000168743.1
Npepps
aminopeptidase puromycin sensitive
chr10_+_123264076 0.953 ENSMUST00000050756.7
Fam19a2
family with sequence similarity 19, member A2
chr2_+_91259822 0.953 ENSMUST00000138470.1
Pacsin3
protein kinase C and casein kinase substrate in neurons 3
chr3_-_27153844 0.945 ENSMUST00000176242.2
ENSMUST00000176780.1
Ect2

ect2 oncogene

chr16_-_34262830 0.945 ENSMUST00000114947.1
Kalrn
kalirin, RhoGEF kinase
chr5_+_134986191 0.937 ENSMUST00000094245.2
Cldn3
claudin 3
chr4_-_155222535 0.933 ENSMUST00000084103.3
ENSMUST00000030917.5
Ski

ski sarcoma viral oncogene homolog (avian)

chr9_+_122117258 0.924 ENSMUST00000146832.1
ENSMUST00000139181.1
Snrk

SNF related kinase

chr9_+_102718424 0.918 ENSMUST00000156485.1
ENSMUST00000145937.1
ENSMUST00000134483.1
Amotl2


angiomotin-like 2


chrX_-_74023745 0.916 ENSMUST00000114353.3
ENSMUST00000101458.2
Irak1

interleukin-1 receptor-associated kinase 1

chr2_+_31470207 0.912 ENSMUST00000102840.4
Ass1
argininosuccinate synthetase 1
chr17_-_25942821 0.911 ENSMUST00000148382.1
ENSMUST00000145745.1
Pigq

phosphatidylinositol glycan anchor biosynthesis, class Q

chr3_-_121263159 0.905 ENSMUST00000128909.1
Tmem56
transmembrane protein 56
chr11_-_69605829 0.903 ENSMUST00000047889.6
Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr15_+_81811414 0.902 ENSMUST00000023024.7
Tef
thyrotroph embryonic factor
chr11_-_50292302 0.902 ENSMUST00000059458.4
Maml1
mastermind like 1 (Drosophila)
chr19_-_28963863 0.899 ENSMUST00000161813.1
4430402I18Rik
RIKEN cDNA 4430402I18 gene
chr8_+_109868586 0.897 ENSMUST00000179721.1
ENSMUST00000034175.4
Phlpp2

PH domain and leucine rich repeat protein phosphatase 2

chr7_-_142578093 0.895 ENSMUST00000149974.1
ENSMUST00000152754.1
H19

H19 fetal liver mRNA

chr13_-_34345174 0.876 ENSMUST00000040336.5
Slc22a23
solute carrier family 22, member 23
chr11_+_78826575 0.875 ENSMUST00000147875.2
ENSMUST00000141321.1
Lyrm9

LYR motif containing 9

chr17_-_27513341 0.869 ENSMUST00000118161.1
Grm4
glutamate receptor, metabotropic 4
chr3_-_121263314 0.863 ENSMUST00000029777.7
Tmem56
transmembrane protein 56
chr5_-_148399901 0.859 ENSMUST00000048116.8
Slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr6_+_48593927 0.854 ENSMUST00000135151.1
Repin1
replication initiator 1
chr9_+_44981779 0.852 ENSMUST00000034602.7
Cd3d
CD3 antigen, delta polypeptide
chr7_+_110772604 0.852 ENSMUST00000005829.6
Ampd3
adenosine monophosphate deaminase 3
chrX_+_10717451 0.851 ENSMUST00000156321.1
Mid1ip1
Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))
chr11_+_77348272 0.851 ENSMUST00000181283.1
Ssh2
slingshot homolog 2 (Drosophila)
chr3_-_100489324 0.848 ENSMUST00000061455.8
Fam46c
family with sequence similarity 46, member C
chr11_-_5837760 0.840 ENSMUST00000109837.1
Polm
polymerase (DNA directed), mu
chr4_-_151044564 0.839 ENSMUST00000103204.4
Per3
period circadian clock 3
chr7_+_35802593 0.836 ENSMUST00000052454.2
E130304I02Rik
RIKEN cDNA E130304I02 gene
chr10_+_67096456 0.836 ENSMUST00000174317.1
Jmjd1c
jumonji domain containing 1C
chr8_+_20136455 0.832 ENSMUST00000179299.1
ENSMUST00000096485.4
Gm21811

predicted gene, 21811

chrX_+_143518671 0.830 ENSMUST00000134402.1
Pak3
p21 protein (Cdc42/Rac)-activated kinase 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.1 GO:0014826 vein smooth muscle contraction(GO:0014826)
1.4 10.1 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
1.3 5.4 GO:0060032 notochord regression(GO:0060032)
1.1 5.7 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
1.1 3.4 GO:0072034 renal vesicle induction(GO:0072034)
1.0 3.1 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
1.0 4.1 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
1.0 4.9 GO:0075136 response to defenses of other organism involved in symbiotic interaction(GO:0052173) response to host defenses(GO:0052200) response to host(GO:0075136)
0.9 1.8 GO:0036292 DNA rewinding(GO:0036292)
0.9 2.7 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.9 2.6 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.9 2.6 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.8 3.3 GO:1904393 regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393)
0.7 2.0 GO:0070650 actin filament bundle distribution(GO:0070650)
0.6 1.9 GO:0006601 creatine biosynthetic process(GO:0006601)
0.6 1.9 GO:0097350 neutrophil clearance(GO:0097350)
0.6 1.8 GO:0060166 olfactory pit development(GO:0060166)
0.6 2.4 GO:0090472 dibasic protein processing(GO:0090472)
0.6 3.3 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.5 0.5 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.5 1.5 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.5 1.5 GO:0001951 intestinal D-glucose absorption(GO:0001951) terminal web assembly(GO:1902896)
0.5 6.3 GO:0060174 limb bud formation(GO:0060174)
0.5 1.0 GO:0070343 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
0.5 1.9 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.5 2.8 GO:0045218 zonula adherens maintenance(GO:0045218)
0.5 3.2 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.4 1.2 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.4 2.0 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.4 1.2 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.4 2.8 GO:0098885 modification of postsynaptic actin cytoskeleton(GO:0098885)
0.4 3.1 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.4 1.2 GO:0007521 muscle cell fate determination(GO:0007521) positive regulation of macrophage apoptotic process(GO:2000111)
0.4 1.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.4 1.1 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.4 4.8 GO:0000052 citrulline metabolic process(GO:0000052)
0.4 0.7 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.4 1.1 GO:0046959 habituation(GO:0046959)
0.4 1.1 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.3 1.0 GO:0019085 early viral transcription(GO:0019085)
0.3 0.3 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.3 1.0 GO:1904173 regulation of histone demethylase activity (H3-K4 specific)(GO:1904173)
0.3 3.5 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.3 0.9 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.3 0.9 GO:0003162 atrioventricular node development(GO:0003162)
0.3 0.8 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.3 0.8 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
0.3 0.8 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.3 2.2 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.3 1.0 GO:0042420 dopamine catabolic process(GO:0042420)
0.2 1.7 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.2 1.0 GO:0033580 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
0.2 1.9 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.2 1.2 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.2 0.7 GO:1903011 negative regulation of bone development(GO:1903011)
0.2 0.7 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.2 0.7 GO:0035106 operant conditioning(GO:0035106)
0.2 0.9 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.2 1.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.2 0.4 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.2 0.9 GO:0035470 positive regulation of vascular wound healing(GO:0035470)
0.2 0.8 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.2 3.3 GO:0016322 neuron remodeling(GO:0016322)
0.2 0.4 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.2 0.6 GO:0071918 urea transmembrane transport(GO:0071918)
0.2 0.6 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.2 1.0 GO:0032423 regulation of mismatch repair(GO:0032423)
0.2 0.8 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.2 1.0 GO:0015871 choline transport(GO:0015871)
0.2 1.9 GO:0090527 actin filament reorganization(GO:0090527)
0.2 1.7 GO:0071420 cellular response to histamine(GO:0071420)
0.2 0.6 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.2 0.9 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.2 0.7 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.2 0.5 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.2 0.9 GO:0032298 positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
0.2 1.9 GO:0042473 outer ear morphogenesis(GO:0042473)
0.2 0.5 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) negative regulation of regulatory T cell differentiation(GO:0045590) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.2 0.5 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.2 0.6 GO:1990379 lipid transport across blood brain barrier(GO:1990379)
0.2 1.4 GO:0014842 skeletal muscle satellite cell proliferation(GO:0014841) regulation of skeletal muscle satellite cell proliferation(GO:0014842) skeletal muscle cell proliferation(GO:0014856) regulation of skeletal muscle cell proliferation(GO:0014857)
0.2 1.1 GO:0035826 rubidium ion transport(GO:0035826) cellular hypotonic response(GO:0071476)
0.2 1.1 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.2 1.5 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.2 0.6 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.2 0.3 GO:1903275 positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278)
0.1 1.8 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.1 1.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 0.6 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 1.6 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.1 0.7 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.1 1.0 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 0.9 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.1 0.6 GO:0044849 estrous cycle(GO:0044849) cholangiocyte apoptotic process(GO:1902488) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.1 0.4 GO:0099541 diacylglycerol catabolic process(GO:0046340) trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.1 1.0 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.1 0.8 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.4 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.1 4.6 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 0.5 GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.1 0.4 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.1 0.4 GO:0019441 tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218) kynurenine metabolic process(GO:0070189)
0.1 0.7 GO:0036006 response to macrophage colony-stimulating factor(GO:0036005) cellular response to macrophage colony-stimulating factor stimulus(GO:0036006)
0.1 0.9 GO:0032264 IMP salvage(GO:0032264)
0.1 0.8 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 0.6 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 0.4 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) DNA replication preinitiation complex assembly(GO:0071163) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 0.2 GO:0007567 parturition(GO:0007567)
0.1 0.8 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 3.6 GO:0061157 mRNA destabilization(GO:0061157)
0.1 1.0 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.1 0.8 GO:0060923 muscle cell fate commitment(GO:0042693) cardiac muscle cell fate commitment(GO:0060923)
0.1 1.8 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.1 0.7 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 1.3 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 0.3 GO:0009153 purine deoxyribonucleotide biosynthetic process(GO:0009153)
0.1 0.9 GO:0045059 positive thymic T cell selection(GO:0045059)
0.1 0.3 GO:0006059 hexitol metabolic process(GO:0006059) alditol biosynthetic process(GO:0019401)
0.1 0.7 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.1 0.3 GO:1903286 regulation of potassium ion import(GO:1903286)
0.1 1.0 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.1 GO:0090194 negative regulation of glomerular mesangial cell proliferation(GO:0072125) negative regulation of glomerulus development(GO:0090194)
0.1 1.1 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.1 1.2 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.1 1.4 GO:0043517 inactivation of MAPK activity(GO:0000188) positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1 1.2 GO:0036065 fucosylation(GO:0036065)
0.1 1.4 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.8 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 0.3 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.1 0.5 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.1 0.4 GO:2000832 androgen secretion(GO:0035935) testosterone secretion(GO:0035936) positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626) negative regulation of steroid hormone secretion(GO:2000832) regulation of androgen secretion(GO:2000834) regulation of testosterone secretion(GO:2000843)
0.1 0.3 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.1 0.6 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1 0.3 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.1 0.5 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.1 0.6 GO:0070932 histone H3 deacetylation(GO:0070932)
0.1 1.6 GO:0010107 potassium ion import(GO:0010107)
0.1 0.8 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 5.1 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 0.3 GO:0045054 constitutive secretory pathway(GO:0045054)
0.1 0.2 GO:0019372 lipoxygenase pathway(GO:0019372)
0.1 0.2 GO:0035963 response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.1 0.6 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.1 0.2 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.4 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.1 0.6 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.1 1.0 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.4 GO:0006868 glutamine transport(GO:0006868)
0.1 1.2 GO:0035994 response to muscle stretch(GO:0035994)
0.1 0.3 GO:0043129 surfactant homeostasis(GO:0043129)
0.1 0.4 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.1 0.6 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 0.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.3 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 0.4 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 1.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.7 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.4 GO:0044351 macropinocytosis(GO:0044351)
0.1 0.2 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.1 3.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 0.8 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 0.7 GO:0070475 rRNA base methylation(GO:0070475)
0.1 1.2 GO:0032060 bleb assembly(GO:0032060)
0.1 0.6 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 1.3 GO:2001273 regulation of glucose import in response to insulin stimulus(GO:2001273)
0.1 0.6 GO:0033572 transferrin transport(GO:0033572)
0.1 1.0 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.2 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.1 0.9 GO:0045214 sarcomere organization(GO:0045214)
0.1 0.9 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.1 0.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.4 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.7 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1 1.7 GO:0035329 hippo signaling(GO:0035329)
0.1 1.2 GO:0042304 regulation of fatty acid biosynthetic process(GO:0042304)
0.1 0.7 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 0.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.2 GO:0046073 dTMP biosynthetic process(GO:0006231) dTMP metabolic process(GO:0046073)
0.1 0.8 GO:0015809 arginine transport(GO:0015809)
0.1 0.3 GO:0032570 response to progesterone(GO:0032570)
0.1 1.1 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 1.0 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.1 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.1 0.9 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.1 0.2 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.1 1.1 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 0.9 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.1 0.3 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.1 0.4 GO:0015862 uridine transport(GO:0015862)
0.0 0.6 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 2.5 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.2 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.2 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 0.4 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) protein K29-linked ubiquitination(GO:0035519) negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 1.2 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.7 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.7 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 1.0 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.1 GO:0009814 defense response, incompatible interaction(GO:0009814)
0.0 0.3 GO:0033129 positive regulation of histone phosphorylation(GO:0033129)
0.0 0.4 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 0.4 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.4 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.2 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.5 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 2.3 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.3 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) asymmetric neuroblast division(GO:0055059)
0.0 0.6 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.0 0.7 GO:0008209 androgen metabolic process(GO:0008209)
0.0 0.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.3 GO:0044806 strand invasion(GO:0042148) G-quadruplex DNA unwinding(GO:0044806)
0.0 0.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.2 GO:0003096 renal sodium ion transport(GO:0003096)
0.0 0.4 GO:0022410 circadian sleep/wake cycle process(GO:0022410) regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187) circadian sleep/wake cycle, sleep(GO:0050802)
0.0 0.5 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.3 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.6 GO:0009109 coenzyme catabolic process(GO:0009109)
0.0 0.1 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.7 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.1 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.2 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.2 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.0 0.1 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.7 GO:0046326 positive regulation of glucose import(GO:0046326)
0.0 0.7 GO:1900048 positive regulation of blood coagulation(GO:0030194) positive regulation of hemostasis(GO:1900048)
0.0 1.8 GO:0006661 phosphatidylinositol biosynthetic process(GO:0006661)
0.0 0.3 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.2 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 1.0 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 2.9 GO:0048709 oligodendrocyte differentiation(GO:0048709)
0.0 0.4 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.3 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.2 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.1 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.5 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.2 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.2 GO:0043507 positive regulation of JUN kinase activity(GO:0043507)
0.0 0.2 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.0 1.1 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779) tetrapyrrole biosynthetic process(GO:0033014)
0.0 0.2 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 1.7 GO:0032414 positive regulation of ion transmembrane transporter activity(GO:0032414)
0.0 1.9 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.3 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.0 0.5 GO:0014887 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 0.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.1 GO:0010155 regulation of proton transport(GO:0010155)
0.0 0.4 GO:0033005 positive regulation of mast cell activation(GO:0033005) positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.3 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 3.3 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.1 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 1.2 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.9 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 0.3 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.3 GO:0001658 branching involved in ureteric bud morphogenesis(GO:0001658)
0.0 0.3 GO:0001553 luteinization(GO:0001553)
0.0 0.9 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.2 GO:0006105 succinyl-CoA metabolic process(GO:0006104) succinate metabolic process(GO:0006105)
0.0 0.6 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.3 GO:0048820 hair follicle maturation(GO:0048820)
0.0 0.3 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.0 0.1 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.1 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.1 GO:0036481 intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036481)
0.0 0.2 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.3 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.5 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.1 GO:2000505 regulation of energy homeostasis(GO:2000505)
0.0 0.2 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.1 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.2 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.1 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.6 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.6 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.7 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812)
0.0 0.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.8 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.1 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0 0.2 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.3 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.1 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.0 0.1 GO:0051715 negative regulation of natural killer cell activation(GO:0032815) cytolysis in other organism(GO:0051715)
0.0 1.4 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.0 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.0 0.4 GO:0007517 muscle organ development(GO:0007517)
0.0 0.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.1 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
0.0 0.1 GO:0061050 regulation of cell growth involved in cardiac muscle cell development(GO:0061050)
0.0 0.2 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.3 GO:0019827 stem cell population maintenance(GO:0019827) maintenance of cell number(GO:0098727)
0.0 1.1 GO:0006821 chloride transport(GO:0006821)
0.0 0.6 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.1 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.0 0.5 GO:0042267 natural killer cell mediated immunity(GO:0002228) natural killer cell mediated cytotoxicity(GO:0042267)
0.0 0.2 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.6 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.3 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.1 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.0 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.0 0.4 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.2 GO:1903077 negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.1 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.1 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.4 GO:0006396 RNA processing(GO:0006396)
0.0 0.0 GO:2001016 positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.0 0.6 GO:0045454 cell redox homeostasis(GO:0045454)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.0 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.7 4.1 GO:0016011 dystroglycan complex(GO:0016011)
0.6 1.7 GO:0099573 glutamatergic postsynaptic density(GO:0099573)
0.5 5.5 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.5 1.4 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.4 2.2 GO:1990761 growth cone lamellipodium(GO:1990761)
0.4 5.7 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.4 5.4 GO:0097542 ciliary tip(GO:0097542)
0.3 2.0 GO:0097513 myosin II filament(GO:0097513)
0.3 1.0 GO:1990423 RZZ complex(GO:1990423)
0.3 5.5 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.3 1.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.3 1.9 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.3 10.1 GO:0060077 inhibitory synapse(GO:0060077)
0.3 2.8 GO:0005915 zonula adherens(GO:0005915)
0.2 4.0 GO:1990635 proximal dendrite(GO:1990635)
0.2 2.7 GO:0032426 stereocilium tip(GO:0032426)
0.2 1.0 GO:0097651 phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.2 4.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 1.9 GO:0043657 host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657)
0.2 1.2 GO:0035976 AP1 complex(GO:0035976)
0.2 1.0 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.2 0.9 GO:0097149 centralspindlin complex(GO:0097149)
0.2 1.7 GO:1902711 GABA-A receptor complex(GO:1902711)
0.2 0.8 GO:0043293 apoptosome(GO:0043293)
0.2 0.4 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.2 0.9 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2 0.9 GO:1990357 terminal web(GO:1990357)
0.2 1.4 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.2 1.0 GO:0098536 deuterosome(GO:0098536)
0.2 1.5 GO:0042587 glycogen granule(GO:0042587)
0.2 1.0 GO:0008091 spectrin(GO:0008091)
0.2 0.8 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2 2.7 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.2 0.5 GO:0044299 C-fiber(GO:0044299)
0.1 0.1 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.6 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1 0.4 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 0.5 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.1 1.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.4 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.1 1.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 2.7 GO:0001741 XY body(GO:0001741)
0.1 0.6 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 0.6 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1 0.3 GO:0097454 Schwann cell microvillus(GO:0097454)
0.1 1.6 GO:0042555 MCM complex(GO:0042555)
0.1 1.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 3.2 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 0.9 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 3.1 GO:0090544 BAF-type complex(GO:0090544)
0.1 0.4 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 3.6 GO:0043596 nuclear replication fork(GO:0043596)
0.1 0.5 GO:0005796 Golgi lumen(GO:0005796)
0.1 0.5 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 0.8 GO:0070852 cell body fiber(GO:0070852)
0.1 3.5 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 0.6 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.5 GO:0071439 clathrin complex(GO:0071439)
0.1 0.8 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 1.0 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 1.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 0.6 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 9.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 1.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.9 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.4 GO:0005859 muscle myosin complex(GO:0005859)
0.1 1.3 GO:0033270 paranode region of axon(GO:0033270)
0.1 0.3 GO:0032389 MutLalpha complex(GO:0032389)
0.1 0.5 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.8 GO:0031527 filopodium membrane(GO:0031527)
0.0 3.2 GO:0016528 sarcoplasm(GO:0016528)
0.0 0.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.0 3.2 GO:0031519 PcG protein complex(GO:0031519)
0.0 4.5 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 10.7 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 1.1 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 1.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 1.8 GO:0043209 myelin sheath(GO:0043209)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0044194 cytolytic granule(GO:0044194)
0.0 2.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.8 GO:0043218 compact myelin(GO:0043218)
0.0 0.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.7 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.2 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.2 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.1 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.8 GO:0005604 basement membrane(GO:0005604)
0.0 2.0 GO:0031594 neuromuscular junction(GO:0031594)
0.0 2.8 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.9 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.4 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 0.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.2 GO:0043296 apical junction complex(GO:0043296)
0.0 0.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 2.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.8 GO:0030175 filopodium(GO:0030175)
0.0 0.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.5 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.7 GO:0001772 immunological synapse(GO:0001772)
0.0 0.5 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.0 0.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.5 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 1.0 GO:0005811 lipid particle(GO:0005811)
0.0 2.1 GO:0030027 lamellipodium(GO:0030027)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 1.0 GO:0043235 receptor complex(GO:0043235)
0.0 0.9 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 6.2 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.2 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.8 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.4 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.3 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.8 GO:0005802 trans-Golgi network(GO:0005802)
0.0 3.8 GO:0005912 adherens junction(GO:0005912)
0.0 0.0 GO:0097447 dendritic tree(GO:0097447)
0.0 0.6 GO:0005643 nuclear pore(GO:0005643)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.2 GO:0004962 endothelin receptor activity(GO:0004962)
1.4 10.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
1.4 5.5 GO:0004035 alkaline phosphatase activity(GO:0004035)
1.1 5.7 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
1.1 5.5 GO:0042289 MHC class II protein binding(GO:0042289)
0.9 4.4 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.5 1.6 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.5 3.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.5 4.1 GO:0043237 laminin-1 binding(GO:0043237)
0.4 1.8 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.4 1.7 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.4 1.7 GO:0051378 serotonin binding(GO:0051378)
0.4 1.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.4 3.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.4 1.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.3 4.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.3 1.0 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.3 1.0 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.3 1.2 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.3 3.1 GO:0070097 delta-catenin binding(GO:0070097)
0.2 1.2 GO:0035184 histone threonine kinase activity(GO:0035184)
0.2 1.9 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.2 1.0 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.2 2.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.2 1.9 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.2 2.1 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.2 4.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 1.4 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.2 0.7 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.2 2.7 GO:0017081 chloride channel regulator activity(GO:0017081)
0.2 0.6 GO:0004998 transferrin receptor activity(GO:0004998)
0.2 0.6 GO:0047710 bis(5'-adenosyl)-triphosphatase activity(GO:0047710)
0.2 1.4 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.2 1.9 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.2 1.5 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.2 1.9 GO:0032036 myosin heavy chain binding(GO:0032036)
0.2 0.4 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.2 2.0 GO:0048406 nerve growth factor binding(GO:0048406)
0.2 0.5 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.2 0.8 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.2 1.0 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.2 0.5 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.2 1.0 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.2 1.1 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.2 1.8 GO:0036310 annealing helicase activity(GO:0036310)
0.1 0.4 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.6 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 3.8 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.3 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 1.5 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.4 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.6 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 1.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.7 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 2.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 1.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 3.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.7 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 0.5 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 4.0 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.4 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.4 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.1 0.9 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.6 GO:0015265 urea channel activity(GO:0015265)
0.1 1.0 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.1 5.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.5 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.9 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.4 GO:0070012 oligopeptidase activity(GO:0070012)
0.1 0.9 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 0.4 GO:0048495 Roundabout binding(GO:0048495)
0.1 2.3 GO:0030506 ankyrin binding(GO:0030506)
0.1 3.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.3 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.1 1.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.8 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 2.9 GO:0042805 actinin binding(GO:0042805)
0.1 0.6 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 1.0 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.6 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.7 GO:0071253 connexin binding(GO:0071253)
0.1 1.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.3 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.1 2.2 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 0.6 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.1 1.0 GO:0031996 thioesterase binding(GO:0031996)
0.1 0.9 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.6 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.4 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 1.0 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.9 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.4 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 0.2 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.1 0.4 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.9 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.2 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.8 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.2 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 1.6 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.1 1.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 0.3 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1 0.9 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.6 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 0.5 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 0.6 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 1.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.7 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.1 0.7 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 1.0 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.1 1.0 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.2 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.1 1.1 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 0.3 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.5 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.9 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.6 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.9 GO:0035198 miRNA binding(GO:0035198)
0.0 0.5 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.7 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.2 GO:0004954 icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)
0.0 0.3 GO:0019206 nucleoside kinase activity(GO:0019206)
0.0 0.2 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.0 4.0 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.5 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.6 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 3.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 3.5 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.6 GO:0001012 RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0 0.4 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.3 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.3 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.6 GO:0000975 regulatory region DNA binding(GO:0000975) transcription regulatory region DNA binding(GO:0044212)
0.0 0.1 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.0 0.2 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 1.3 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.5 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.8 GO:0070888 E-box binding(GO:0070888)
0.0 1.0 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.5 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.2 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.4 GO:0001047 core promoter binding(GO:0001047)
0.0 1.2 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.1 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 2.0 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.0 2.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 6.3 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.8 GO:0034061 DNA-directed DNA polymerase activity(GO:0003887) DNA polymerase activity(GO:0034061)
0.0 0.3 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 2.4 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.4 GO:0051861 glycolipid binding(GO:0051861)
0.0 0.6 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.5 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.7 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.6 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.5 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 1.0 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.2 GO:0046983 protein dimerization activity(GO:0046983)
0.0 0.5 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.9 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.2 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.9 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.3 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.1 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.3 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 2.9 GO:0051015 actin filament binding(GO:0051015)
0.0 0.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.0 9.9 GO:0003682 chromatin binding(GO:0003682)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.3 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.5 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.2 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.4 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0043142 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.7 GO:0030332 cyclin binding(GO:0030332)
0.0 0.4 GO:0050661 NADP binding(GO:0050661)
0.0 4.5 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.3 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.8 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.6 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.1 GO:0009374 biotin binding(GO:0009374)
0.0 0.1 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.7 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 0.2 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.5 GO:0050699 WW domain binding(GO:0050699)
0.0 0.4 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.2 GO:0005542 folic acid binding(GO:0005542)
0.0 0.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.5 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.3 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.4 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.3 9.2 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.2 7.1 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.2 10.5 PID_ENDOTHELIN_PATHWAY Endothelins
0.1 6.1 NABA_COLLAGENS Genes encoding collagen proteins
0.1 3.4 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.1 2.8 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.1 4.1 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 0.2 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.1 2.2 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.1 2.8 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 1.1 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 3.0 PID_TXA2PATHWAY Thromboxane A2 receptor signaling
0.1 2.9 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.1 1.4 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.1 2.1 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.1 1.5 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 3.0 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 1.3 PID_ARF6_PATHWAY Arf6 signaling events
0.1 2.2 PID_REELIN_PATHWAY Reelin signaling pathway
0.1 2.2 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.0 PID_VEGFR1_PATHWAY VEGFR1 specific signals
0.0 0.6 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.3 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 1.2 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 0.9 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.1 PID_CD8_TCR_PATHWAY TCR signaling in naïve CD8+ T cells
0.0 3.4 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.2 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.4 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.5 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 2.2 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 1.2 PID_ATR_PATHWAY ATR signaling pathway
0.0 1.0 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.0 1.6 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 1.1 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.0 0.9 PID_FGF_PATHWAY FGF signaling pathway
0.0 1.0 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 1.2 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 0.6 PID_TNF_PATHWAY TNF receptor signaling pathway
0.0 0.5 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 0.2 PID_TCR_PATHWAY TCR signaling in naïve CD4+ T cells
0.0 1.4 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.0 0.4 PID_ARF_3PATHWAY Arf1 pathway
0.0 0.2 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 0.6 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.3 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.7 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.8 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.5 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 0.2 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.0 0.2 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 0.2 PID_ALK1_PATHWAY ALK1 signaling events
0.0 1.8 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.1 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 0.4 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.1 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.0 0.0 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.3 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 0.2 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 0.1 PID_ALK2_PATHWAY ALK2 signaling events
0.0 0.4 PID_P53_REGULATION_PATHWAY p53 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.0 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.4 10.1 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.3 4.8 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.3 2.4 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 1.7 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2 5.4 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 3.7 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 3.6 REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT Genes involved in Ligand-gated ion channel transport
0.2 1.2 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 4.6 REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.1 0.7 REACTOME_SIGNALING_BY_ERBB2 Genes involved in Signaling by ERBB2
0.1 2.4 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 4.6 REACTOME_ION_CHANNEL_TRANSPORT Genes involved in Ion channel transport
0.1 1.9 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.1 0.9 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 4.7 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS Genes involved in Trafficking of AMPA receptors
0.1 1.5 REACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1 3.7 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 1.1 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 6.1 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.1 2.8 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 1.0 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 1.2 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 8.4 REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS Genes involved in G alpha (q) signalling events
0.1 1.7 REACTOME_INWARDLY_RECTIFYING_K_CHANNELS Genes involved in Inwardly rectifying K+ channels
0.1 2.9 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 1.0 REACTOME_ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 0.6 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.9 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.2 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.1 0.5 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 0.9 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 0.5 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.5 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 0.3 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.1 1.8 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.1 0.4 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 0.9 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 2.5 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.1 0.3 REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1 1.4 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 1.2 REACTOME_RORA_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.6 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.4 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.0 1.4 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.3 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.6 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.4 REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.5 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.4 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.9 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.4 REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.1 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.5 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.6 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.5 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.4 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.1 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.0 0.9 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 1.7 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.8 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.9 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.7 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.2 REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.2 REACTOME_ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.5 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.6 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.3 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.5 REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.8 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.3 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.1 REACTOME_G_ALPHA1213_SIGNALLING_EVENTS Genes involved in G alpha (12/13) signalling events
0.0 1.0 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.2 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.3 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.5 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.2 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 1.4 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.4 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.0 0.5 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.2 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.3 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.2 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation