Motif ID: Arnt

Z-value: 0.766


Transcription factors associated with Arnt:

Gene SymbolEntrez IDGene Name
Arnt ENSMUSG00000015522.12 Arnt

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Arntmm10_v2_chr3_+_95434386_95434428-0.314.6e-02Click!


Activity profile for motif Arnt.

activity profile for motif Arnt


Sorted Z-values histogram for motif Arnt

Sorted Z-values for motif Arnt



Network of associatons between targets according to the STRING database.



First level regulatory network of Arnt

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_30065333 8.812 ENSMUST00000023171.7
Hes1
hairy and enhancer of split 1 (Drosophila)
chr4_+_125490688 7.777 ENSMUST00000030676.7
Grik3
glutamate receptor, ionotropic, kainate 3
chr5_+_75075464 5.698 ENSMUST00000160104.1
ENSMUST00000040477.3
Gsx2

GS homeobox 2

chr8_-_46294592 5.504 ENSMUST00000058636.7
Helt
helt bHLH transcription factor
chr6_+_108660616 4.995 ENSMUST00000032194.4
Bhlhe40
basic helix-loop-helix family, member e40
chr6_+_108660772 4.259 ENSMUST00000163617.1
Bhlhe40
basic helix-loop-helix family, member e40
chr2_+_84839395 4.100 ENSMUST00000146816.1
ENSMUST00000028469.7
Slc43a1

solute carrier family 43, member 1

chr5_-_45639501 3.972 ENSMUST00000016023.7
Fam184b
family with sequence similarity 184, member B
chr10_+_22158566 3.319 ENSMUST00000181645.1
ENSMUST00000105522.2
Raet1e
H60b
retinoic acid early transcript 1E
histocompatibility 60b
chr13_+_108316332 3.297 ENSMUST00000051594.5
Depdc1b
DEP domain containing 1B
chr12_-_56535047 3.248 ENSMUST00000178477.2
Nkx2-1
NK2 homeobox 1
chr13_+_108316395 3.244 ENSMUST00000171178.1
Depdc1b
DEP domain containing 1B
chr15_-_74672560 3.175 ENSMUST00000023268.7
ENSMUST00000110009.3
Arc

activity regulated cytoskeletal-associated protein

chr3_+_131110350 2.978 ENSMUST00000066849.6
ENSMUST00000106341.2
ENSMUST00000029611.7
Lef1


lymphoid enhancer binding factor 1


chr11_+_98937669 2.955 ENSMUST00000107475.2
ENSMUST00000068133.3
Rara

retinoic acid receptor, alpha

chr17_+_56040350 2.817 ENSMUST00000002914.8
Chaf1a
chromatin assembly factor 1, subunit A (p150)
chr17_+_27556613 2.500 ENSMUST00000117600.1
ENSMUST00000114888.3
Hmga1

high mobility group AT-hook 1

chr17_+_27556641 2.467 ENSMUST00000119486.1
ENSMUST00000118599.1
Hmga1

high mobility group AT-hook 1

chr11_+_82388900 2.453 ENSMUST00000054245.4
ENSMUST00000092852.2
Tmem132e

transmembrane protein 132E

chr9_-_22389113 2.329 ENSMUST00000040912.7
Anln
anillin, actin binding protein
chr17_+_27556668 2.304 ENSMUST00000117254.1
ENSMUST00000118570.1
Hmga1

high mobility group AT-hook 1

chr15_+_74721193 2.254 ENSMUST00000070923.1
Them6
thioesterase superfamily member 6
chr3_+_137864573 2.223 ENSMUST00000174561.1
ENSMUST00000173790.1
H2afz

H2A histone family, member Z

chr3_+_137864487 2.212 ENSMUST00000041045.7
H2afz
H2A histone family, member Z
chr3_-_95882193 2.186 ENSMUST00000159863.1
ENSMUST00000159739.1
ENSMUST00000036418.3
Gm129


predicted gene 129


chr2_+_121449362 1.877 ENSMUST00000110615.1
ENSMUST00000099475.5
Serf2

small EDRK-rich factor 2

chr5_-_149051300 1.868 ENSMUST00000110505.1
Hmgb1
high mobility group box 1
chr1_+_84839833 1.781 ENSMUST00000097672.3
Fbxo36
F-box protein 36
chr2_+_122234749 1.760 ENSMUST00000110551.3
Sord
sorbitol dehydrogenase
chr9_-_20976762 1.744 ENSMUST00000054197.5
S1pr2
sphingosine-1-phosphate receptor 2
chr19_-_10203880 1.741 ENSMUST00000142241.1
ENSMUST00000116542.2
ENSMUST00000025651.5
ENSMUST00000156291.1
Fen1



flap structure specific endonuclease 1



chr4_-_97778042 1.696 ENSMUST00000146447.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr11_-_17211504 1.690 ENSMUST00000020317.7
Pno1
partner of NOB1 homolog (S. cerevisiae)
chrX_+_134601179 1.647 ENSMUST00000074950.4
ENSMUST00000113203.1
ENSMUST00000113202.1
Hnrnph2


heterogeneous nuclear ribonucleoprotein H2


chr5_-_52566264 1.619 ENSMUST00000039750.5
Lgi2
leucine-rich repeat LGI family, member 2
chr18_+_53176345 1.589 ENSMUST00000037850.5
Snx2
sorting nexin 2
chr5_-_106458440 1.570 ENSMUST00000086795.6
Barhl2
BarH-like 2 (Drosophila)
chr11_-_64436653 1.562 ENSMUST00000177999.1
F930015N05Rik
RIKEN cDNA F930015N05 gene
chr19_+_41911851 1.496 ENSMUST00000011896.6
Pgam1
phosphoglycerate mutase 1
chr6_-_6217023 1.444 ENSMUST00000015256.8
Slc25a13
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13
chrX_+_134601271 1.438 ENSMUST00000050331.6
ENSMUST00000059297.5
Hnrnph2

heterogeneous nuclear ribonucleoprotein H2

chr11_+_101316200 1.418 ENSMUST00000142640.1
ENSMUST00000019470.7
Psme3

proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)

chr13_+_55321991 1.369 ENSMUST00000021942.6
Prelid1
PRELI domain containing 1
chr9_-_121857952 1.328 ENSMUST00000060251.6
Higd1a
HIG1 domain family, member 1A
chr17_-_65613521 1.323 ENSMUST00000024897.8
Vapa
vesicle-associated membrane protein, associated protein A
chr3_-_153725062 1.294 ENSMUST00000064460.5
St6galnac3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr1_+_9545397 1.287 ENSMUST00000072079.7
Rrs1
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr3_-_95882232 1.266 ENSMUST00000161866.1
Gm129
predicted gene 129
chr10_+_42502197 1.255 ENSMUST00000105499.1
Snx3
sorting nexin 3
chr6_-_125165576 1.231 ENSMUST00000183272.1
ENSMUST00000182052.1
ENSMUST00000182277.1
Gapdh


glyceraldehyde-3-phosphate dehydrogenase


chr3_-_95882031 1.212 ENSMUST00000161994.1
Gm129
predicted gene 129
chr7_+_110122299 1.159 ENSMUST00000033326.8
Wee1
WEE 1 homolog 1 (S. pombe)
chr9_+_107569112 1.144 ENSMUST00000010191.7
Hyal2
hyaluronoglucosaminidase 2
chr1_-_178337774 1.131 ENSMUST00000037748.7
Hnrnpu
heterogeneous nuclear ribonucleoprotein U
chr7_+_28810928 1.114 ENSMUST00000174477.1
Hnrnpl
heterogeneous nuclear ribonucleoprotein L
chr6_-_125165707 1.112 ENSMUST00000118875.1
Gapdh
glyceraldehyde-3-phosphate dehydrogenase
chr13_+_37826225 1.102 ENSMUST00000128570.1
Rreb1
ras responsive element binding protein 1
chr7_+_28810886 1.072 ENSMUST00000038572.8
Hnrnpl
heterogeneous nuclear ribonucleoprotein L
chr1_-_75219245 1.065 ENSMUST00000079464.6
Tuba4a
tubulin, alpha 4A
chr10_+_42502030 1.061 ENSMUST00000105500.1
ENSMUST00000019939.5
Snx3

sorting nexin 3

chr7_+_100159241 1.034 ENSMUST00000032967.3
Lipt2
lipoyl(octanoyl) transferase 2 (putative)
chr5_+_115011111 1.021 ENSMUST00000031530.5
Sppl3
signal peptide peptidase 3
chr9_-_78480736 1.019 ENSMUST00000156988.1
Eef1a1
eukaryotic translation elongation factor 1 alpha 1
chr2_+_31572651 1.008 ENSMUST00000113482.1
Fubp3
far upstream element (FUSE) binding protein 3
chr3_-_107458895 1.001 ENSMUST00000009617.8
Kcnc4
potassium voltage gated channel, Shaw-related subfamily, member 4
chr2_+_31572775 0.994 ENSMUST00000137889.1
Fubp3
far upstream element (FUSE) binding protein 3
chr5_-_149636331 0.973 ENSMUST00000074846.7
ENSMUST00000110498.1
ENSMUST00000127977.1
ENSMUST00000132412.1
Hsph1



heat shock 105kDa/110kDa protein 1



chr4_+_101419696 0.956 ENSMUST00000131397.1
ENSMUST00000133055.1
Ak4

adenylate kinase 4

chr6_-_85451248 0.950 ENSMUST00000113770.1
ENSMUST00000032080.2
Pradc1

protease-associated domain containing 1

chr9_-_110654161 0.937 ENSMUST00000133191.1
ENSMUST00000167320.1
Nbeal2

neurobeachin-like 2

chr9_-_99876147 0.936 ENSMUST00000054819.8
Sox14
SRY-box containing gene 14
chr10_-_4387436 0.931 ENSMUST00000100077.3
Zbtb2
zinc finger and BTB domain containing 2
chr11_+_120491840 0.922 ENSMUST00000026899.3
Slc25a10
solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10
chr19_-_42129043 0.909 ENSMUST00000018965.3
Avpi1
arginine vasopressin-induced 1
chr5_+_76951307 0.899 ENSMUST00000031160.9
ENSMUST00000120912.1
ENSMUST00000117536.1
Paics


phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase


chr2_+_31572701 0.890 ENSMUST00000055244.6
Fubp3
far upstream element (FUSE) binding protein 3
chr8_+_13159135 0.881 ENSMUST00000033824.6
Lamp1
lysosomal-associated membrane protein 1
chr11_-_93885752 0.880 ENSMUST00000066888.3
Utp18
UTP18, small subunit (SSU) processome component, homolog (yeast)
chr19_+_41981709 0.875 ENSMUST00000026170.1
Ubtd1
ubiquitin domain containing 1
chr3_-_90052463 0.865 ENSMUST00000029553.9
ENSMUST00000064639.8
ENSMUST00000090908.6
Ubap2l


ubiquitin associated protein 2-like


chr1_-_17097839 0.859 ENSMUST00000038382.4
Jph1
junctophilin 1
chr13_-_38658991 0.856 ENSMUST00000001757.7
Eef1e1
eukaryotic translation elongation factor 1 epsilon 1
chr11_-_76217490 0.853 ENSMUST00000102500.4
Gemin4
gem (nuclear organelle) associated protein 4
chr4_-_41275091 0.837 ENSMUST00000030143.6
ENSMUST00000108068.1
Ubap2

ubiquitin-associated protein 2

chr2_+_75659253 0.832 ENSMUST00000111964.1
ENSMUST00000111962.1
ENSMUST00000111961.1
ENSMUST00000164947.2
ENSMUST00000090792.4
Hnrnpa3




heterogeneous nuclear ribonucleoprotein A3




chr15_+_98167806 0.823 ENSMUST00000031914.4
AI836003
expressed sequence AI836003
chrX_-_134600976 0.818 ENSMUST00000033621.6
Gla
galactosidase, alpha
chr4_+_128654686 0.802 ENSMUST00000030588.6
ENSMUST00000136377.1
Phc2

polyhomeotic-like 2 (Drosophila)

chr1_+_17727034 0.801 ENSMUST00000159958.1
ENSMUST00000160305.1
ENSMUST00000095075.4
Crispld1


cysteine-rich secretory protein LCCL domain containing 1


chr1_+_23761749 0.793 ENSMUST00000144602.1
B3gat2
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chr4_+_152325831 0.789 ENSMUST00000103191.4
ENSMUST00000139685.1
Rpl22

ribosomal protein L22

chr8_+_56294552 0.781 ENSMUST00000034026.8
Hpgd
hydroxyprostaglandin dehydrogenase 15 (NAD)
chr15_-_79834224 0.760 ENSMUST00000109623.1
ENSMUST00000109625.1
ENSMUST00000023060.6
ENSMUST00000089299.5
Cbx6

Npcd

chromobox 6

neuronal pentraxin chromo domain

chr4_-_137048695 0.760 ENSMUST00000049583.7
Zbtb40
zinc finger and BTB domain containing 40
chr11_+_78178651 0.756 ENSMUST00000092880.7
ENSMUST00000127587.1
ENSMUST00000108338.1
Tlcd1


TLC domain containing 1


chr4_-_108833544 0.738 ENSMUST00000102740.1
ENSMUST00000102741.1
Btf3l4

basic transcription factor 3-like 4

chr8_-_45999860 0.729 ENSMUST00000053558.9
Ankrd37
ankyrin repeat domain 37
chr5_+_76951382 0.718 ENSMUST00000141687.1
Paics
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase
chr14_-_52197216 0.702 ENSMUST00000046709.7
Supt16
suppressor of Ty 16
chr9_+_120492606 0.698 ENSMUST00000007139.4
Eif1b
eukaryotic translation initiation factor 1B
chr7_+_127967457 0.695 ENSMUST00000106251.3
ENSMUST00000077609.5
ENSMUST00000121616.2
Fus


fused in sarcoma


chr11_+_69935796 0.685 ENSMUST00000018698.5
Ybx2
Y box protein 2
chr8_-_124949165 0.658 ENSMUST00000034469.5
Egln1
EGL nine homolog 1 (C. elegans)
chr2_-_131160006 0.650 ENSMUST00000103188.3
ENSMUST00000133602.1
ENSMUST00000028800.5
1700037H04Rik


RIKEN cDNA 1700037H04 gene


chr16_+_94085226 0.643 ENSMUST00000072182.7
Sim2
single-minded homolog 2 (Drosophila)
chr16_-_5049882 0.634 ENSMUST00000023189.7
ENSMUST00000115844.1
Glyr1

glyoxylate reductase 1 homolog (Arabidopsis)

chr17_-_33940299 0.633 ENSMUST00000173363.1
ENSMUST00000174048.1
ENSMUST00000179418.1
ENSMUST00000174426.1
ENSMUST00000025163.7
H2-Ke2




H2-K region expressed gene 2




chr5_+_120116480 0.631 ENSMUST00000031590.8
Rbm19
RNA binding motif protein 19
chr8_+_62951195 0.623 ENSMUST00000118003.1
Spock3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3
chr2_+_85037448 0.615 ENSMUST00000168266.1
ENSMUST00000130729.1
Ssrp1

structure specific recognition protein 1

chr5_-_137786681 0.610 ENSMUST00000132726.1
Mepce
methylphosphate capping enzyme
chr15_+_99126513 0.608 ENSMUST00000063517.4
Spats2
spermatogenesis associated, serine-rich 2
chr6_-_91473361 0.605 ENSMUST00000040835.7
Chchd4
coiled-coil-helix-coiled-coil-helix domain containing 4
chr17_-_33824346 0.595 ENSMUST00000173879.1
ENSMUST00000166693.2
ENSMUST00000173019.1
ENSMUST00000087342.6
ENSMUST00000173844.1
Rps28




ribosomal protein S28




chr10_-_85916902 0.591 ENSMUST00000037646.7
Prdm4
PR domain containing 4
chr19_+_43440404 0.580 ENSMUST00000165311.1
Cnnm1
cyclin M1
chr2_+_144368961 0.578 ENSMUST00000028911.8
ENSMUST00000147747.1
ENSMUST00000183618.1
Csrp2bp

Pet117
cysteine and glycine-rich protein 2 binding protein

PET117 homolog (S. cerevisiae)
chr14_-_50930803 0.575 ENSMUST00000160538.1
ENSMUST00000162957.1
ENSMUST00000161166.1
ENSMUST00000160835.1
ENSMUST00000049312.7
Tmem55b




transmembrane protein 55b




chr10_-_79766872 0.573 ENSMUST00000047203.8
Rnf126
ring finger protein 126
chr14_-_55660397 0.562 ENSMUST00000002400.6
Mdp1
magnesium-dependent phosphatase 1
chr17_-_56935388 0.559 ENSMUST00000025053.8
Mllt1
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
chr12_+_76837408 0.556 ENSMUST00000041008.9
Fntb
farnesyltransferase, CAAX box, beta
chr5_-_137786651 0.553 ENSMUST00000031740.9
Mepce
methylphosphate capping enzyme
chr15_-_36608959 0.553 ENSMUST00000001809.8
Pabpc1
poly(A) binding protein, cytoplasmic 1
chr19_+_55741810 0.541 ENSMUST00000111657.3
ENSMUST00000061496.9
ENSMUST00000041717.7
ENSMUST00000111662.4
Tcf7l2



transcription factor 7 like 2, T cell specific, HMG box



chr2_+_130274437 0.518 ENSMUST00000141872.1
Nop56
NOP56 ribonucleoprotein
chr19_-_42128982 0.513 ENSMUST00000161873.1
Avpi1
arginine vasopressin-induced 1
chrX_-_136068236 0.513 ENSMUST00000049130.7
Bex2
brain expressed X-linked 2
chr5_-_76951560 0.510 ENSMUST00000140076.1
Ppat
phosphoribosyl pyrophosphate amidotransferase
chr2_+_130274424 0.508 ENSMUST00000103198.4
Nop56
NOP56 ribonucleoprotein
chr6_+_125131869 0.504 ENSMUST00000044200.8
Nop2
NOP2 nucleolar protein
chr17_-_27133902 0.503 ENSMUST00000119227.1
ENSMUST00000025045.8
Uqcc2

ubiquinol-cytochrome c reductase complex assembly factor 2

chr15_-_79834323 0.495 ENSMUST00000177316.2
ENSMUST00000175858.2
Nptxr

neuronal pentraxin receptor

chr17_-_45573253 0.489 ENSMUST00000165127.1
ENSMUST00000166469.1
ENSMUST00000024739.7
Hsp90ab1


heat shock protein 90 alpha (cytosolic), class B member 1


chr10_-_62486772 0.487 ENSMUST00000105447.3
Vps26a
vacuolar protein sorting 26 homolog A (yeast)
chr7_-_45466894 0.484 ENSMUST00000033093.8
Bax
BCL2-associated X protein
chr19_-_4625612 0.470 ENSMUST00000025823.3
Rce1
RCE1 homolog, prenyl protein peptidase (S. cerevisiae)
chr19_-_5424759 0.464 ENSMUST00000148219.2
Drap1
Dr1 associated protein 1 (negative cofactor 2 alpha)
chr11_-_102697710 0.463 ENSMUST00000164506.2
ENSMUST00000092569.6
Ccdc43

coiled-coil domain containing 43

chr5_-_65435717 0.460 ENSMUST00000117542.1
Ugdh
UDP-glucose dehydrogenase
chr18_+_10617768 0.458 ENSMUST00000002551.3
Snrpd1
small nuclear ribonucleoprotein D1
chr1_+_74506044 0.447 ENSMUST00000087215.5
Rqcd1
rcd1 (required for cell differentiation) homolog 1 (S. pombe)
chr15_+_80255184 0.443 ENSMUST00000109605.3
Atf4
activating transcription factor 4
chr10_+_127677064 0.440 ENSMUST00000118612.1
ENSMUST00000048099.4
Tmem194

transmembrane protein 194

chr16_-_4790220 0.435 ENSMUST00000118703.1
Cdip1
cell death inducing Trp53 target 1
chr13_-_54687696 0.429 ENSMUST00000177950.1
ENSMUST00000146931.1
Rnf44

ring finger protein 44

chr11_+_3289168 0.417 ENSMUST00000134089.1
Patz1
POZ (BTB) and AT hook containing zinc finger 1
chr2_+_167503089 0.414 ENSMUST00000078050.6
Rnf114
ring finger protein 114
chr3_+_88297115 0.410 ENSMUST00000001452.7
Cct3
chaperonin containing Tcp1, subunit 3 (gamma)
chr3_+_88297147 0.409 ENSMUST00000164166.1
ENSMUST00000168062.1
Cct3

chaperonin containing Tcp1, subunit 3 (gamma)

chr2_+_158028687 0.405 ENSMUST00000109518.1
ENSMUST00000029180.7
Rprd1b

regulation of nuclear pre-mRNA domain containing 1B

chr4_-_139352538 0.404 ENSMUST00000102503.3
Mrto4
MRT4, mRNA turnover 4, homolog (S. cerevisiae)
chr5_-_65435881 0.403 ENSMUST00000031103.7
Ugdh
UDP-glucose dehydrogenase
chr19_-_60581013 0.398 ENSMUST00000111460.3
ENSMUST00000081790.7
ENSMUST00000166712.1
Cacul1


CDK2 associated, cullin domain 1


chr3_-_96727436 0.396 ENSMUST00000154679.1
Polr3c
polymerase (RNA) III (DNA directed) polypeptide C
chr15_+_79347534 0.393 ENSMUST00000096350.3
Maff
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
chr15_-_79834261 0.390 ENSMUST00000148358.1
Cbx6
chromobox 6
chr11_+_3289880 0.382 ENSMUST00000110043.1
ENSMUST00000094471.3
Patz1

POZ (BTB) and AT hook containing zinc finger 1

chr2_-_26237368 0.376 ENSMUST00000036187.8
Qsox2
quiescin Q6 sulfhydryl oxidase 2
chr4_-_139352298 0.371 ENSMUST00000030513.6
ENSMUST00000155257.1
Mrto4

MRT4, mRNA turnover 4, homolog (S. cerevisiae)

chr3_-_96727566 0.371 ENSMUST00000029741.2
Polr3c
polymerase (RNA) III (DNA directed) polypeptide C
chr7_+_28741968 0.368 ENSMUST00000094632.4
Sars2
seryl-aminoacyl-tRNA synthetase 2
chr11_-_50325599 0.366 ENSMUST00000179865.1
ENSMUST00000020637.8
Canx

calnexin

chr4_-_151044564 0.365 ENSMUST00000103204.4
Per3
period circadian clock 3
chr11_+_74898078 0.364 ENSMUST00000045807.7
Tsr1
TSR1 20S rRNA accumulation
chr2_+_158028481 0.364 ENSMUST00000103123.3
Rprd1b
regulation of nuclear pre-mRNA domain containing 1B
chr4_+_123917420 0.364 ENSMUST00000030399.6
Rragc
Ras-related GTP binding C
chr2_-_165034770 0.361 ENSMUST00000122070.1
ENSMUST00000121377.1
Ncoa5

nuclear receptor coactivator 5

chr2_+_173737492 0.356 ENSMUST00000067530.4
Vapb
vesicle-associated membrane protein, associated protein B and C
chr17_-_26939464 0.356 ENSMUST00000025027.8
ENSMUST00000114935.1
Cuta

cutA divalent cation tolerance homolog (E. coli)

chr7_+_3704307 0.355 ENSMUST00000108624.1
ENSMUST00000126562.1
Rps9

ribosomal protein S9

chr10_-_115315546 0.347 ENSMUST00000020343.7
Rab21
RAB21, member RAS oncogene family
chr11_+_97703394 0.345 ENSMUST00000103147.4
Psmb3
proteasome (prosome, macropain) subunit, beta type 3
chr9_+_21368014 0.334 ENSMUST00000067646.4
ENSMUST00000115414.1
Ilf3

interleukin enhancer binding factor 3

chr16_+_45158725 0.333 ENSMUST00000023343.3
Atg3
autophagy related 3
chr9_-_91365778 0.329 ENSMUST00000065360.3
Zic1
zinc finger protein of the cerebellum 1
chr11_+_3202612 0.327 ENSMUST00000110049.1
Eif4enif1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr1_+_23762003 0.326 ENSMUST00000140583.1
B3gat2
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chr14_-_46390576 0.323 ENSMUST00000074077.5
Bmp4
bone morphogenetic protein 4
chr2_-_165034821 0.322 ENSMUST00000153905.1
ENSMUST00000040381.8
Ncoa5

nuclear receptor coactivator 5

chr3_+_41564880 0.322 ENSMUST00000168086.1
Phf17
PHD finger protein 17
chr11_-_115536181 0.317 ENSMUST00000118155.1
ENSMUST00000153892.1
Sumo2

SMT3 suppressor of mif two 3 homolog 2 (yeast)

chr2_+_90847149 0.313 ENSMUST00000136872.1
Mtch2
mitochondrial carrier homolog 2 (C. elegans)
chr19_-_5424906 0.312 ENSMUST00000113674.1
ENSMUST00000025853.9
Drap1

Dr1 associated protein 1 (negative cofactor 2 alpha)

chr12_-_59219725 0.311 ENSMUST00000043204.7
Fbxo33
F-box protein 33
chr3_+_90052814 0.310 ENSMUST00000160640.1
ENSMUST00000029552.6
ENSMUST00000162114.1
ENSMUST00000068798.6
4933434E20Rik



RIKEN cDNA 4933434E20 gene



chr7_+_3703979 0.310 ENSMUST00000006496.8
Rps9
ribosomal protein S9
chr3_+_96727611 0.308 ENSMUST00000029740.9
Rnf115
ring finger protein 115
chr14_-_46390501 0.300 ENSMUST00000100676.2
Bmp4
bone morphogenetic protein 4
chr3_+_107595031 0.291 ENSMUST00000014747.1
Alx3
aristaless-like homeobox 3
chr3_-_96727453 0.285 ENSMUST00000141377.1
ENSMUST00000125183.1
Polr3c

polymerase (RNA) III (DNA directed) polypeptide C

chr9_-_35558522 0.253 ENSMUST00000034612.5
Ddx25
DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
chr11_+_60417238 0.251 ENSMUST00000070681.6
Gid4
GID complex subunit 4, VID24 homolog (S. cerevisiae)
chr2_+_90940397 0.249 ENSMUST00000068726.6
ENSMUST00000005643.7
ENSMUST00000177642.1
ENSMUST00000111451.3
ENSMUST00000068747.7
Celf1




CUGBP, Elav-like family member 1




chr7_+_3704025 0.241 ENSMUST00000108623.1
ENSMUST00000139818.1
ENSMUST00000108625.1
Rps9


ribosomal protein S9


chr7_-_28741749 0.240 ENSMUST00000171183.1
Mrps12
mitochondrial ribosomal protein S12
chr7_-_28981787 0.239 ENSMUST00000066070.5
Eif3k
eukaryotic translation initiation factor 3, subunit K
chr7_-_27166413 0.236 ENSMUST00000108382.1
Egln2
EGL nine homolog 2 (C. elegans)
chr7_-_28741780 0.234 ENSMUST00000056078.8
Mrps12
mitochondrial ribosomal protein S12
chr11_+_95666957 0.232 ENSMUST00000125172.1
ENSMUST00000036374.5
Phb

prohibitin


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.8 GO:0021557 oculomotor nerve development(GO:0021557)
1.1 3.2 GO:0021759 globus pallidus development(GO:0021759)
1.0 3.0 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
1.0 3.0 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.8 2.4 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.8 2.3 GO:1904170 regulation of bleb assembly(GO:1904170)
0.7 7.8 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.6 1.9 GO:0045819 plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819)
0.6 1.8 GO:0019405 hexitol metabolic process(GO:0006059) alditol catabolic process(GO:0019405) fructose biosynthetic process(GO:0046370)
0.6 2.3 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.5 3.2 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.5 1.5 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.5 5.7 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.4 5.5 GO:0097154 GABAergic neuron differentiation(GO:0097154)
0.4 1.1 GO:2000373 regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.4 1.4 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.3 1.7 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.3 1.0 GO:0009106 lipoate metabolic process(GO:0009106)
0.3 1.6 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.3 0.9 GO:0070889 platelet alpha granule organization(GO:0070889)
0.3 0.9 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626) positive regulation of natural killer cell degranulation(GO:0043323)
0.3 1.7 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.3 1.7 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.3 0.5 GO:0006543 glutamine catabolic process(GO:0006543)
0.2 0.5 GO:0036363 transforming growth factor beta activation(GO:0036363)
0.2 1.0 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345) positive regulation of NK T cell activation(GO:0051135)
0.2 0.5 GO:1903519 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.2 0.9 GO:0015744 succinate transport(GO:0015744)
0.2 0.7 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.2 0.9 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.2 0.7 GO:0033122 regulation of purine nucleotide catabolic process(GO:0033121) negative regulation of purine nucleotide catabolic process(GO:0033122) regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.2 2.2 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.2 0.6 GO:0048389 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134) negative regulation of immature T cell proliferation in thymus(GO:0033088) cloaca development(GO:0035844) intermediate mesoderm development(GO:0048389) regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994) pattern specification involved in mesonephros development(GO:0061227) regulation of hepatocyte differentiation(GO:0070366) anterior/posterior pattern specification involved in kidney development(GO:0072098) negative regulation of glomerular mesangial cell proliferation(GO:0072125) metanephric S-shaped body morphogenesis(GO:0072284) negative regulation of glomerulus development(GO:0090194) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462) cardiac jelly development(GO:1905072) negative regulation of cell proliferation involved in heart morphogenesis(GO:2000137)
0.2 4.4 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.2 1.0 GO:0045759 negative regulation of action potential(GO:0045759)
0.2 1.1 GO:2000484 hyaluronan catabolic process(GO:0030214) positive regulation of interleukin-8 secretion(GO:2000484)
0.2 1.3 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.2 4.9 GO:0009649 entrainment of circadian clock(GO:0009649)
0.2 0.9 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.2 1.4 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.2 7.3 GO:0006284 base-excision repair(GO:0006284)
0.2 1.4 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.1 1.0 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 1.2 GO:0035562 negative regulation of chromatin binding(GO:0035562) snRNA modification(GO:0040031)
0.1 1.6 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.6 GO:0018343 protein farnesylation(GO:0018343)
0.1 0.1 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241)
0.1 3.3 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.1 0.4 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.1 1.1 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601) positive regulation of lamellipodium morphogenesis(GO:2000394)
0.1 0.2 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.1 0.4 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1 0.6 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.2 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 0.8 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.1 0.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 3.0 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 1.0 GO:1990173 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.1 0.9 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1 0.8 GO:0007567 parturition(GO:0007567) ductus arteriosus closure(GO:0097070)
0.1 2.5 GO:0015804 neutral amino acid transport(GO:0015804)
0.1 0.1 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.1 0.1 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630) positive regulation of aminoacyl-tRNA ligase activity(GO:1903632)
0.1 0.6 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.5 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 1.2 GO:0006677 glycosylceramide metabolic process(GO:0006677)
0.1 1.5 GO:0090201 negative regulation of release of cytochrome c from mitochondria(GO:0090201)
0.1 0.9 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 0.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 0.4 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.1 0.2 GO:0015886 heme transport(GO:0015886)
0.1 0.5 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.1 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 6.8 GO:0030177 positive regulation of Wnt signaling pathway(GO:0030177)
0.0 0.5 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 1.0 GO:0046033 AMP metabolic process(GO:0046033)
0.0 0.7 GO:0030204 chondroitin sulfate metabolic process(GO:0030204)
0.0 0.3 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.0 0.6 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.0 0.6 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 1.6 GO:0001709 cell fate determination(GO:0001709)
0.0 0.2 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.0 0.3 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 1.3 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 1.0 GO:1903427 negative regulation of reactive oxygen species biosynthetic process(GO:1903427)
0.0 0.1 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.0 0.4 GO:0045187 regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.2 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.9 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.0 0.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 1.1 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.1 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.2 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.8 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.6 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.0 0.6 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.0 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0 0.0 GO:0070094 positive regulation of glucagon secretion(GO:0070094)
0.0 0.5 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.1 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.4 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.3 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.0 0.4 GO:0000154 rRNA modification(GO:0000154)
0.0 0.5 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 0.0 GO:0035984 response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.0 0.7 GO:0048255 mRNA stabilization(GO:0048255)
0.0 0.1 GO:0051503 adenine nucleotide transport(GO:0051503)
0.0 0.8 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 1.4 GO:2000045 regulation of G1/S transition of mitotic cell cycle(GO:2000045)
0.0 0.2 GO:0042407 cristae formation(GO:0042407)
0.0 0.8 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.4 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.6 GO:0009880 embryonic pattern specification(GO:0009880)
0.0 0.7 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.3 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.6 GO:0006040 amino sugar metabolic process(GO:0006040)
0.0 1.4 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.4 GO:1903432 regulation of TORC1 signaling(GO:1903432)
0.0 0.9 GO:0006413 translational initiation(GO:0006413)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 7.3 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.9 2.8 GO:0033186 CAF-1 complex(GO:0033186)
0.8 3.3 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.6 4.4 GO:0001740 Barr body(GO:0001740)
0.5 1.6 GO:0030905 retromer, tubulation complex(GO:0030905)
0.5 2.3 GO:0005826 actomyosin contractile ring(GO:0005826)
0.4 1.4 GO:0008537 proteasome activator complex(GO:0008537)
0.3 2.3 GO:0097452 GAIT complex(GO:0097452)
0.3 3.5 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.3 0.9 GO:0044194 cytolytic granule(GO:0044194)
0.2 0.7 GO:0035101 FACT complex(GO:0035101)
0.2 2.3 GO:0032009 early phagosome(GO:0032009)
0.2 1.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.2 8.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.2 1.0 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.2 1.4 GO:0010009 cytoplasmic side of endosome membrane(GO:0010009)
0.2 0.6 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.2 1.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.2 0.9 GO:0030314 junctional membrane complex(GO:0030314)
0.1 1.0 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.5 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 0.4 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.1 1.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 0.5 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 2.2 GO:0045120 pronucleus(GO:0045120)
0.1 0.5 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.1 1.0 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 1.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.4 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.9 GO:0034719 SMN-Sm protein complex(GO:0034719)
0.1 0.7 GO:0044327 dendritic spine head(GO:0044327)
0.1 7.0 GO:0016363 nuclear matrix(GO:0016363)
0.1 0.9 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.2 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 1.1 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.4 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.8 GO:0035102 PRC1 complex(GO:0035102)
0.0 1.9 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 1.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.5 GO:0046930 pore complex(GO:0046930)
0.0 0.3 GO:0033391 chromatoid body(GO:0033391)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.2 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 1.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 1.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.1 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 1.3 GO:0070469 respiratory chain(GO:0070469)
0.0 1.0 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.6 GO:0000786 nucleosome(GO:0000786)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.3 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.5 GO:0015935 small ribosomal subunit(GO:0015935)
0.0 0.1 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 1.7 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 0.6 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.7 GO:0005844 polysome(GO:0005844)
0.0 0.5 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 8.3 GO:0016604 nuclear body(GO:0016604)
0.0 0.6 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 1.0 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 4.2 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.0 GO:0000125 PCAF complex(GO:0000125)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.5 GO:0030173 integral component of Golgi membrane(GO:0030173)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 7.7 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
1.5 9.3 GO:0043426 MRF binding(GO:0043426)
0.8 2.3 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.7 7.3 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.6 1.9 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.5 1.5 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.5 3.0 GO:0030284 estrogen receptor activity(GO:0030284)
0.5 1.4 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.4 3.3 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.4 1.6 GO:1990460 leptin receptor binding(GO:1990460)
0.4 1.4 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.4 2.8 GO:0070087 chromo shadow domain binding(GO:0070087)
0.3 1.7 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.3 8.8 GO:0008432 JUN kinase binding(GO:0008432)
0.3 1.0 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.3 0.9 GO:0015140 malate transmembrane transporter activity(GO:0015140) succinate transmembrane transporter activity(GO:0015141)
0.3 0.9 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
0.3 1.1 GO:0030292 hyalurononglucosaminidase activity(GO:0004415) protein tyrosine kinase inhibitor activity(GO:0030292)
0.3 3.2 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.2 3.0 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.2 2.2 GO:1990715 mRNA CDS binding(GO:1990715)
0.2 1.7 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.2 0.6 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.2 0.8 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.2 0.6 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.2 0.6 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.2 1.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.2 0.5 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.2 2.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.2 1.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.2 0.8 GO:0004954 icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)
0.2 0.9 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 0.8 GO:0016936 galactoside binding(GO:0016936)
0.1 2.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 1.0 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 1.1 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.5 GO:0001847 opsonin receptor activity(GO:0001847)
0.1 0.7 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 0.4 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.1 1.0 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 0.3 GO:0019776 Atg8 ligase activity(GO:0019776)
0.1 1.0 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 1.3 GO:0008097 5S rRNA binding(GO:0008097)
0.1 4.1 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 0.4 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 0.3 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.1 4.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.6 GO:0039706 co-receptor binding(GO:0039706)
0.1 1.6 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.1 0.5 GO:0051434 BH3 domain binding(GO:0051434)
0.1 1.1 GO:0001056 RNA polymerase III activity(GO:0001056)
0.1 0.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 0.5 GO:1990446 U1 snRNP binding(GO:1990446)
0.1 0.2 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.7 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.5 GO:0031386 protein tag(GO:0031386)
0.0 1.1 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 0.1 GO:0031893 vasopressin receptor binding(GO:0031893)
0.0 0.6 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.5 GO:0070016 gamma-catenin binding(GO:0045295) armadillo repeat domain binding(GO:0070016)
0.0 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 1.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.9 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.9 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.5 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.9 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.7 GO:0031491 nucleosome binding(GO:0031491)
0.0 1.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 4.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)
0.0 0.1 GO:0005436 sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.0 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 1.1 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.7 GO:0045182 translation regulator activity(GO:0045182)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 1.8 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 1.8 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616)
0.0 0.9 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 1.0 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.7 GO:0019003 GDP binding(GO:0019003)
0.0 4.3 GO:0045296 cadherin binding(GO:0045296)
0.0 1.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.2 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.5 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.9 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.2 8.8 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 1.2 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 7.3 PID_IL4_2PATHWAY IL4-mediated signaling events
0.1 3.3 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 1.7 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 7.4 PID_CMYB_PATHWAY C-MYB transcription factor network
0.1 2.0 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.1 2.5 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.0 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.6 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.0 3.0 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.2 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.6 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 2.4 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.6 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.6 PID_BMP_PATHWAY BMP receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 7.3 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.4 7.8 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 7.7 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.2 1.7 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.2 2.1 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2 3.3 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 6.2 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 1.3 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.9 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 4.4 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.1 1.2 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 1.1 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 4.1 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 0.9 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.1 2.1 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 4.1 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 0.5 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 1.1 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 1.0 REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 7.7 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.1 0.6 REACTOME_ELONGATION_ARREST_AND_RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.4 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.7 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.8 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.0 0.4 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 6.4 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.0 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.9 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.0 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.7 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.1 REACTOME_SPHINGOLIPID_METABOLISM Genes involved in Sphingolipid metabolism
0.0 1.8 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 1.8 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.0 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.4 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.9 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.0 0.9 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.7 REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 0.3 REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING Genes involved in p75 NTR receptor-mediated signalling