Motif ID: Nr5a2
Z-value: 0.639

Transcription factors associated with Nr5a2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Nr5a2 | ENSMUSG00000026398.8 | Nr5a2 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 1.5 | GO:2000501 | natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501) |
0.4 | 2.7 | GO:0001980 | regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980) |
0.4 | 1.2 | GO:0014877 | response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) membrane depolarization during Purkinje myocyte cell action potential(GO:0086047) |
0.4 | 2.4 | GO:0042776 | mitochondrial ATP synthesis coupled proton transport(GO:0042776) |
0.3 | 1.0 | GO:0015772 | disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772) |
0.3 | 0.9 | GO:0046133 | pyrimidine ribonucleoside catabolic process(GO:0046133) |
0.3 | 0.9 | GO:0035672 | regulation of cellular pH reduction(GO:0032847) oligopeptide transmembrane transport(GO:0035672) |
0.3 | 2.5 | GO:1990845 | adaptive thermogenesis(GO:1990845) |
0.2 | 1.0 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
0.2 | 2.7 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
0.2 | 1.2 | GO:0019244 | lactate biosynthetic process from pyruvate(GO:0019244) |
0.2 | 0.7 | GO:0021933 | radial glia guided migration of cerebellar granule cell(GO:0021933) |
0.2 | 1.6 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
0.2 | 0.6 | GO:0097212 | lysosomal membrane organization(GO:0097212) |
0.2 | 0.6 | GO:1902445 | regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445) |
0.2 | 0.6 | GO:0019043 | establishment of viral latency(GO:0019043) |
0.2 | 1.1 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
0.2 | 0.5 | GO:0030200 | heparan sulfate proteoglycan catabolic process(GO:0030200) |
0.2 | 0.9 | GO:1903215 | negative regulation of protein targeting to mitochondrion(GO:1903215) |
0.2 | 0.5 | GO:0019401 | alditol biosynthetic process(GO:0019401) |
0.2 | 0.5 | GO:0017055 | negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055) |
0.2 | 0.5 | GO:2000823 | regulation of androgen receptor activity(GO:2000823) |
0.2 | 1.2 | GO:0072615 | interleukin-17 secretion(GO:0072615) |
0.1 | 0.4 | GO:0072076 | nephrogenic mesenchyme development(GO:0072076) |
0.1 | 0.4 | GO:0003104 | positive regulation of glomerular filtration(GO:0003104) negative regulation of protein import into nucleus, translocation(GO:0033159) regulation of oligodendrocyte apoptotic process(GO:1900141) negative regulation of oligodendrocyte apoptotic process(GO:1900142) positive regulation of dendritic cell chemotaxis(GO:2000510) |
0.1 | 0.3 | GO:0003100 | regulation of systemic arterial blood pressure by endothelin(GO:0003100) |
0.1 | 0.7 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
0.1 | 0.5 | GO:0006933 | negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933) |
0.1 | 0.6 | GO:0018171 | peptidyl-cysteine oxidation(GO:0018171) |
0.1 | 0.8 | GO:1901552 | positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142) |
0.1 | 0.4 | GO:0014826 | vein smooth muscle contraction(GO:0014826) |
0.1 | 0.3 | GO:0006106 | fumarate metabolic process(GO:0006106) |
0.1 | 0.7 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
0.1 | 1.2 | GO:0002536 | respiratory burst involved in inflammatory response(GO:0002536) negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665) |
0.1 | 0.6 | GO:0045578 | negative regulation of B cell differentiation(GO:0045578) |
0.1 | 0.4 | GO:0009814 | defense response, incompatible interaction(GO:0009814) |
0.1 | 0.2 | GO:1903538 | meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538) |
0.1 | 0.7 | GO:0071394 | cellular response to testosterone stimulus(GO:0071394) |
0.1 | 0.3 | GO:0051754 | meiotic sister chromatid cohesion, centromeric(GO:0051754) |
0.1 | 0.3 | GO:0030210 | heparin biosynthetic process(GO:0030210) |
0.1 | 1.2 | GO:0006228 | UTP biosynthetic process(GO:0006228) |
0.1 | 0.6 | GO:0072513 | positive regulation of secondary heart field cardioblast proliferation(GO:0072513) |
0.1 | 0.8 | GO:0006390 | transcription from mitochondrial promoter(GO:0006390) |
0.1 | 0.3 | GO:0010360 | negative regulation of anion channel activity(GO:0010360) |
0.1 | 2.3 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.1 | 0.4 | GO:0006121 | mitochondrial electron transport, succinate to ubiquinone(GO:0006121) |
0.1 | 0.4 | GO:0042535 | positive regulation of tumor necrosis factor biosynthetic process(GO:0042535) |
0.1 | 0.3 | GO:0034334 | adherens junction maintenance(GO:0034334) |
0.1 | 0.3 | GO:0045041 | protein import into mitochondrial intermembrane space(GO:0045041) |
0.1 | 0.5 | GO:0006172 | ADP biosynthetic process(GO:0006172) |
0.1 | 0.3 | GO:0046604 | positive regulation of mitotic centrosome separation(GO:0046604) |
0.1 | 0.3 | GO:0010756 | positive regulation of plasminogen activation(GO:0010756) |
0.1 | 0.2 | GO:0042823 | pyridoxal phosphate biosynthetic process(GO:0042823) |
0.1 | 0.9 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
0.1 | 0.2 | GO:1904719 | excitatory chemical synaptic transmission(GO:0098976) positive regulation of AMPA glutamate receptor clustering(GO:1904719) |
0.1 | 0.2 | GO:0071544 | diphosphoinositol polyphosphate catabolic process(GO:0071544) |
0.1 | 0.5 | GO:0009249 | protein lipoylation(GO:0009249) |
0.1 | 0.3 | GO:2000195 | negative regulation of female gonad development(GO:2000195) |
0.1 | 0.4 | GO:0042866 | pyruvate biosynthetic process(GO:0042866) |
0.1 | 0.2 | GO:0033364 | mast cell secretory granule organization(GO:0033364) |
0.1 | 0.2 | GO:0035606 | peptidyl-cysteine S-trans-nitrosylation(GO:0035606) |
0.1 | 0.6 | GO:0006105 | succinate metabolic process(GO:0006105) |
0.1 | 0.9 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
0.1 | 0.2 | GO:1901856 | negative regulation of cellular respiration(GO:1901856) |
0.1 | 0.3 | GO:2000348 | regulation of CD40 signaling pathway(GO:2000348) |
0.1 | 0.3 | GO:1903300 | negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300) |
0.1 | 0.9 | GO:0000338 | protein deneddylation(GO:0000338) |
0.1 | 0.2 | GO:1902202 | regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202) |
0.0 | 0.1 | GO:1902732 | positive regulation of chondrocyte proliferation(GO:1902732) |
0.0 | 0.1 | GO:0002447 | eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308) |
0.0 | 1.8 | GO:0010614 | negative regulation of cardiac muscle hypertrophy(GO:0010614) |
0.0 | 0.5 | GO:0097067 | cellular response to thyroid hormone stimulus(GO:0097067) |
0.0 | 0.5 | GO:0033601 | positive regulation of mammary gland epithelial cell proliferation(GO:0033601) |
0.0 | 0.3 | GO:0034331 | cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217) |
0.0 | 0.5 | GO:2000653 | regulation of genetic imprinting(GO:2000653) |
0.0 | 5.1 | GO:0006334 | nucleosome assembly(GO:0006334) |
0.0 | 1.7 | GO:0097031 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
0.0 | 0.3 | GO:0016576 | histone dephosphorylation(GO:0016576) |
0.0 | 0.2 | GO:0097491 | trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491) |
0.0 | 0.5 | GO:0006654 | phosphatidic acid biosynthetic process(GO:0006654) |
0.0 | 0.8 | GO:0034389 | lipid particle organization(GO:0034389) |
0.0 | 0.3 | GO:0007144 | female meiosis I(GO:0007144) |
0.0 | 0.3 | GO:0038203 | TORC2 signaling(GO:0038203) |
0.0 | 0.2 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
0.0 | 0.3 | GO:0006027 | glycosaminoglycan catabolic process(GO:0006027) |
0.0 | 3.5 | GO:0006342 | chromatin silencing(GO:0006342) |
0.0 | 0.2 | GO:0032790 | ribosome disassembly(GO:0032790) |
0.0 | 0.8 | GO:0007614 | short-term memory(GO:0007614) |
0.0 | 0.5 | GO:0048875 | chemical homeostasis within a tissue(GO:0048875) |
0.0 | 0.3 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
0.0 | 1.6 | GO:0009060 | aerobic respiration(GO:0009060) |
0.0 | 0.6 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
0.0 | 0.2 | GO:0006627 | protein processing involved in protein targeting to mitochondrion(GO:0006627) |
0.0 | 0.6 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
0.0 | 0.5 | GO:0042775 | mitochondrial ATP synthesis coupled electron transport(GO:0042775) |
0.0 | 0.8 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
0.0 | 1.4 | GO:0014003 | oligodendrocyte development(GO:0014003) |
0.0 | 0.2 | GO:0031293 | membrane protein intracellular domain proteolysis(GO:0031293) |
0.0 | 1.0 | GO:0042168 | heme metabolic process(GO:0042168) |
0.0 | 0.2 | GO:0048742 | regulation of skeletal muscle fiber development(GO:0048742) |
0.0 | 0.1 | GO:0061622 | glycolytic process through glucose-1-phosphate(GO:0061622) |
0.0 | 0.0 | GO:0042939 | glutathione transport(GO:0034635) tripeptide transport(GO:0042939) |
0.0 | 0.3 | GO:0060484 | male sex determination(GO:0030238) lung-associated mesenchyme development(GO:0060484) |
0.0 | 0.3 | GO:0006662 | glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904) |
0.0 | 0.4 | GO:2000251 | positive regulation of actin cytoskeleton reorganization(GO:2000251) |
0.0 | 0.1 | GO:0061588 | calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591) |
0.0 | 0.8 | GO:0045494 | photoreceptor cell maintenance(GO:0045494) |
0.0 | 0.1 | GO:0042795 | snRNA transcription from RNA polymerase II promoter(GO:0042795) |
0.0 | 0.4 | GO:0030262 | apoptotic nuclear changes(GO:0030262) |
0.0 | 0.3 | GO:0042026 | protein refolding(GO:0042026) |
0.0 | 0.5 | GO:0034260 | negative regulation of GTPase activity(GO:0034260) |
0.0 | 0.4 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
0.0 | 0.5 | GO:0007608 | sensory perception of smell(GO:0007608) |
0.0 | 0.0 | GO:0071649 | regulation of chemokine (C-C motif) ligand 5 production(GO:0071649) |
0.0 | 0.3 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
0.0 | 0.1 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
0.0 | 0.4 | GO:2000398 | regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398) |
0.0 | 0.2 | GO:0033211 | adiponectin-activated signaling pathway(GO:0033211) long-chain fatty acid import(GO:0044539) |
0.0 | 0.4 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
0.0 | 0.2 | GO:0035721 | intraciliary retrograde transport(GO:0035721) |
0.0 | 0.3 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
0.0 | 0.0 | GO:0007196 | adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196) |
0.0 | 0.3 | GO:0045116 | protein neddylation(GO:0045116) |
0.0 | 0.2 | GO:2000060 | positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060) |
0.0 | 0.1 | GO:0006020 | inositol metabolic process(GO:0006020) |
0.0 | 0.1 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
0.0 | 0.0 | GO:0060455 | negative regulation of gastric acid secretion(GO:0060455) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 1.8 | GO:1990584 | cardiac Troponin complex(GO:1990584) |
0.3 | 3.2 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) |
0.2 | 0.9 | GO:0045283 | mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283) |
0.2 | 2.5 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
0.2 | 0.6 | GO:0031680 | G-protein beta/gamma-subunit complex(GO:0031680) |
0.2 | 2.6 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
0.2 | 1.6 | GO:0005753 | mitochondrial proton-transporting ATP synthase complex(GO:0005753) |
0.2 | 1.5 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
0.1 | 1.4 | GO:0072546 | ER membrane protein complex(GO:0072546) |
0.1 | 0.6 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
0.1 | 5.5 | GO:0000786 | nucleosome(GO:0000786) |
0.1 | 0.4 | GO:0097226 | sperm mitochondrial sheath(GO:0097226) |
0.1 | 0.8 | GO:1902710 | GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711) |
0.1 | 0.7 | GO:0005915 | zonula adherens(GO:0005915) |
0.1 | 0.9 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
0.1 | 0.3 | GO:1990761 | growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812) |
0.1 | 0.9 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
0.1 | 0.3 | GO:0001652 | granular component(GO:0001652) |
0.1 | 0.6 | GO:0046930 | pore complex(GO:0046930) |
0.0 | 0.3 | GO:0031314 | extrinsic component of mitochondrial inner membrane(GO:0031314) |
0.0 | 0.1 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) |
0.0 | 0.5 | GO:0032426 | stereocilium tip(GO:0032426) |
0.0 | 0.4 | GO:0098554 | cytoplasmic side of endoplasmic reticulum membrane(GO:0098554) |
0.0 | 0.8 | GO:0031083 | BLOC-1 complex(GO:0031083) |
0.0 | 0.8 | GO:0043220 | Schmidt-Lanterman incisure(GO:0043220) |
0.0 | 0.1 | GO:0072534 | perineuronal net(GO:0072534) |
0.0 | 2.2 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
0.0 | 0.2 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
0.0 | 0.2 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
0.0 | 1.7 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
0.0 | 0.4 | GO:0071439 | clathrin complex(GO:0071439) |
0.0 | 0.4 | GO:0005687 | U4 snRNP(GO:0005687) |
0.0 | 0.2 | GO:0097452 | GAIT complex(GO:0097452) |
0.0 | 0.5 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
0.0 | 0.3 | GO:0031105 | septin complex(GO:0031105) |
0.0 | 0.1 | GO:0005945 | 6-phosphofructokinase complex(GO:0005945) |
0.0 | 0.5 | GO:0045239 | tricarboxylic acid cycle enzyme complex(GO:0045239) |
0.0 | 1.0 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
0.0 | 0.1 | GO:0098560 | cytoplasmic side of late endosome membrane(GO:0098560) |
0.0 | 0.2 | GO:0042629 | mast cell granule(GO:0042629) |
0.0 | 0.3 | GO:0000778 | condensed nuclear chromosome kinetochore(GO:0000778) condensed chromosome outer kinetochore(GO:0000940) |
0.0 | 5.9 | GO:0043209 | myelin sheath(GO:0043209) |
0.0 | 0.3 | GO:0031932 | TORC2 complex(GO:0031932) |
0.0 | 2.4 | GO:0016605 | PML body(GO:0016605) |
0.0 | 0.1 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
0.0 | 0.3 | GO:1990635 | proximal dendrite(GO:1990635) |
0.0 | 0.2 | GO:0090571 | RNA polymerase II transcription repressor complex(GO:0090571) |
0.0 | 0.9 | GO:0008180 | COP9 signalosome(GO:0008180) |
0.0 | 0.3 | GO:1904115 | axon cytoplasm(GO:1904115) |
0.0 | 6.6 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
0.0 | 0.3 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
0.0 | 0.2 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
0.0 | 0.1 | GO:0001520 | outer dense fiber(GO:0001520) |
0.0 | 0.2 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
0.0 | 1.1 | GO:0005604 | basement membrane(GO:0005604) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 2.5 | GO:0017077 | oxidative phosphorylation uncoupler activity(GO:0017077) |
0.6 | 2.4 | GO:0004111 | creatine kinase activity(GO:0004111) |
0.6 | 1.8 | GO:0030172 | troponin C binding(GO:0030172) |
0.3 | 1.0 | GO:0008515 | sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157) |
0.3 | 1.3 | GO:0001847 | opsonin receptor activity(GO:0001847) |
0.3 | 0.9 | GO:0008177 | succinate dehydrogenase (ubiquinone) activity(GO:0008177) |
0.3 | 1.2 | GO:0008142 | oxysterol binding(GO:0008142) |
0.3 | 2.4 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
0.3 | 1.2 | GO:0004459 | L-lactate dehydrogenase activity(GO:0004459) |
0.2 | 0.9 | GO:0004064 | arylesterase activity(GO:0004064) |
0.2 | 3.7 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
0.2 | 0.6 | GO:0052658 | inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) |
0.2 | 4.7 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.2 | 1.0 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
0.2 | 1.3 | GO:0016018 | cyclosporin A binding(GO:0016018) |
0.2 | 1.9 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
0.2 | 0.5 | GO:0070052 | collagen V binding(GO:0070052) |
0.2 | 0.5 | GO:0002153 | steroid receptor RNA activator RNA binding(GO:0002153) |
0.2 | 0.5 | GO:0035939 | microsatellite binding(GO:0035939) |
0.1 | 1.4 | GO:0015266 | protein channel activity(GO:0015266) |
0.1 | 0.8 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
0.1 | 0.8 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
0.1 | 0.9 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
0.1 | 0.4 | GO:0004962 | endothelin receptor activity(GO:0004962) |
0.1 | 0.5 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
0.1 | 0.4 | GO:0004743 | pyruvate kinase activity(GO:0004743) |
0.1 | 0.4 | GO:0004017 | adenylate kinase activity(GO:0004017) |
0.1 | 0.7 | GO:0033142 | progesterone receptor binding(GO:0033142) |
0.1 | 0.3 | GO:0008113 | peptide-methionine (S)-S-oxide reductase activity(GO:0008113) |
0.1 | 0.3 | GO:0030158 | protein xylosyltransferase activity(GO:0030158) |
0.1 | 0.3 | GO:0004517 | nitric-oxide synthase activity(GO:0004517) |
0.1 | 0.2 | GO:0035605 | peptidyl-cysteine S-nitrosylase activity(GO:0035605) |
0.1 | 0.2 | GO:0004069 | L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) |
0.1 | 0.3 | GO:0004703 | G-protein coupled receptor kinase activity(GO:0004703) |
0.1 | 0.5 | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) |
0.1 | 0.2 | GO:0031403 | lithium ion binding(GO:0031403) |
0.1 | 0.3 | GO:0008967 | phosphoglycolate phosphatase activity(GO:0008967) |
0.1 | 0.2 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
0.1 | 1.5 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
0.1 | 1.3 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
0.1 | 1.9 | GO:0009055 | electron carrier activity(GO:0009055) |
0.1 | 0.4 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
0.1 | 0.7 | GO:0070097 | delta-catenin binding(GO:0070097) |
0.1 | 0.6 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
0.1 | 0.2 | GO:0043758 | acetate-CoA ligase (ADP-forming) activity(GO:0043758) |
0.0 | 0.4 | GO:1990446 | U1 snRNP binding(GO:1990446) |
0.0 | 0.2 | GO:2001069 | glycogen binding(GO:2001069) |
0.0 | 0.3 | GO:0044547 | DNA topoisomerase binding(GO:0044547) |
0.0 | 2.6 | GO:0005518 | collagen binding(GO:0005518) |
0.0 | 0.5 | GO:0008301 | DNA binding, bending(GO:0008301) |
0.0 | 0.4 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
0.0 | 0.2 | GO:0000298 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) |
0.0 | 1.1 | GO:0008009 | chemokine activity(GO:0008009) |
0.0 | 0.1 | GO:0001733 | galactosylceramide sulfotransferase activity(GO:0001733) |
0.0 | 0.4 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
0.0 | 0.2 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
0.0 | 0.6 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
0.0 | 0.3 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
0.0 | 0.1 | GO:0003872 | 6-phosphofructokinase activity(GO:0003872) |
0.0 | 0.3 | GO:0004679 | AMP-activated protein kinase activity(GO:0004679) |
0.0 | 0.2 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
0.0 | 0.3 | GO:0015035 | protein disulfide oxidoreductase activity(GO:0015035) |
0.0 | 0.5 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
0.0 | 0.1 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
0.0 | 0.1 | GO:0000832 | inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724) |
0.0 | 0.2 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
0.0 | 0.9 | GO:0016763 | transferase activity, transferring pentosyl groups(GO:0016763) |
0.0 | 0.2 | GO:0038191 | neuropilin binding(GO:0038191) |
0.0 | 0.4 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.0 | 0.3 | GO:0048156 | tau protein binding(GO:0048156) |
0.0 | 0.3 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
0.0 | 0.3 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
0.0 | 0.1 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
0.0 | 0.3 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
0.0 | 0.7 | GO:0020037 | heme binding(GO:0020037) |
0.0 | 2.2 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
0.0 | 0.3 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
0.0 | 0.3 | GO:0008198 | ferrous iron binding(GO:0008198) |
0.0 | 0.3 | GO:0070182 | DNA polymerase binding(GO:0070182) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 0.4 | ST_INTERFERON_GAMMA_PATHWAY | Interferon gamma pathway. |
0.0 | 0.3 | SA_G2_AND_M_PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
0.0 | 0.8 | PID_TCR_CALCIUM_PATHWAY | Calcium signaling in the CD4+ TCR pathway |
0.0 | 0.3 | PID_ALK2_PATHWAY | ALK2 signaling events |
0.0 | 0.1 | PID_INSULIN_GLUCOSE_PATHWAY | Insulin-mediated glucose transport |
0.0 | 1.0 | PID_HNF3B_PATHWAY | FOXA2 and FOXA3 transcription factor networks |
0.0 | 1.1 | PID_HDAC_CLASSII_PATHWAY | Signaling events mediated by HDAC Class II |
0.0 | 1.9 | PID_MYC_ACTIV_PATHWAY | Validated targets of C-MYC transcriptional activation |
0.0 | 0.7 | PID_RAS_PATHWAY | Regulation of Ras family activation |
0.0 | 0.4 | PID_P38_MK2_PATHWAY | p38 signaling mediated by MAPKAP kinases |
0.0 | 0.5 | PID_RXR_VDR_PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
0.0 | 0.3 | PID_FRA_PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
0.0 | 0.8 | PID_MYC_REPRESS_PATHWAY | Validated targets of C-MYC transcriptional repression |
0.0 | 0.7 | PID_INSULIN_PATHWAY | Insulin Pathway |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 1.3 | REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
0.1 | 13.7 | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_ | Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
0.1 | 4.6 | REACTOME_PACKAGING_OF_TELOMERE_ENDS | Genes involved in Packaging Of Telomere Ends |
0.1 | 0.9 | REACTOME_PYRIMIDINE_CATABOLISM | Genes involved in Pyrimidine catabolism |
0.1 | 1.8 | REACTOME_STRIATED_MUSCLE_CONTRACTION | Genes involved in Striated Muscle Contraction |
0.1 | 2.6 | REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT | Genes involved in Mitochondrial Protein Import |
0.0 | 0.8 | REACTOME_PYRUVATE_METABOLISM | Genes involved in Pyruvate metabolism |
0.0 | 0.4 | REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
0.0 | 0.3 | REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION | Genes involved in FGFR4 ligand binding and activation |
0.0 | 0.5 | REACTOME_ACTIVATION_OF_RAC | Genes involved in Activation of Rac |
0.0 | 1.0 | REACTOME_TIGHT_JUNCTION_INTERACTIONS | Genes involved in Tight junction interactions |
0.0 | 0.9 | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
0.0 | 0.3 | REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
0.0 | 2.0 | REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
0.0 | 0.4 | REACTOME_P38MAPK_EVENTS | Genes involved in p38MAPK events |
0.0 | 0.3 | REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
0.0 | 1.5 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
0.0 | 0.2 | REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
0.0 | 0.2 | REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
0.0 | 0.6 | REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA | Genes involved in G beta:gamma signalling through PLC beta |
0.0 | 0.2 | REACTOME_TIE2_SIGNALING | Genes involved in Tie2 Signaling |
0.0 | 0.5 | REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
0.0 | 0.6 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
0.0 | 0.5 | REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING | Genes involved in Growth hormone receptor signaling |
0.0 | 0.1 | REACTOME_KERATAN_SULFATE_DEGRADATION | Genes involved in Keratan sulfate degradation |
0.0 | 1.0 | REACTOME_COLLAGEN_FORMATION | Genes involved in Collagen formation |
0.0 | 0.3 | REACTOME_INHIBITION_OF_THE_PROTEOLYTIC_ACTIVITY_OF_APC_C_REQUIRED_FOR_THE_ONSET_OF_ANAPHASE_BY_MITOTIC_SPINDLE_CHECKPOINT_COMPONENTS | Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components |
0.0 | 0.3 | REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
0.0 | 0.5 | REACTOME_SYNTHESIS_OF_PA | Genes involved in Synthesis of PA |
0.0 | 0.3 | REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
0.0 | 0.1 | REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
0.0 | 0.2 | REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
0.0 | 0.2 | REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle |
0.0 | 0.2 | REACTOME_METABOLISM_OF_POLYAMINES | Genes involved in Metabolism of polyamines |
0.0 | 0.3 | REACTOME_GLUTATHIONE_CONJUGATION | Genes involved in Glutathione conjugation |
0.0 | 0.2 | REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |