Motif ID: Nfe2_Bach1_Mafk

Z-value: 0.845

Transcription factors associated with Nfe2_Bach1_Mafk:

Gene SymbolEntrez IDGene Name
Bach1 ENSMUSG00000025612.5 Bach1
Mafk ENSMUSG00000018143.4 Mafk
Nfe2 ENSMUSG00000058794.6 Nfe2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bach1mm10_v2_chr16_+_87698904_876989590.371.7e-02Click!
Nfe2mm10_v2_chr15_-_103251465_103251705-0.333.4e-02Click!
Mafkmm10_v2_chr5_+_139791513_1397915390.153.6e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Nfe2_Bach1_Mafk

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_5725639 7.822 ENSMUST00000115556.1
ENSMUST00000115555.1
ENSMUST00000115559.3
Dync1i1


dynein cytoplasmic 1 intermediate chain 1


chr1_-_33907721 6.147 ENSMUST00000115161.1
ENSMUST00000062289.8
Bend6

BEN domain containing 6

chr3_+_123267445 4.431 ENSMUST00000047923.7
Sec24d
Sec24 related gene family, member D (S. cerevisiae)
chr2_+_136713444 3.082 ENSMUST00000028727.4
ENSMUST00000110098.3
Snap25

synaptosomal-associated protein 25

chr2_+_155775333 2.595 ENSMUST00000029141.5
Mmp24
matrix metallopeptidase 24
chr5_-_139484420 2.480 ENSMUST00000150992.1
Zfand2a
zinc finger, AN1-type domain 2A
chr13_-_54611332 2.433 ENSMUST00000091609.4
Cltb
clathrin, light polypeptide (Lcb)
chr5_-_139484475 2.429 ENSMUST00000110851.1
ENSMUST00000079996.6
Zfand2a

zinc finger, AN1-type domain 2A

chr13_-_54611274 2.230 ENSMUST00000049575.7
Cltb
clathrin, light polypeptide (Lcb)
chrX_-_103186618 2.194 ENSMUST00000121720.1
Nap1l2
nucleosome assembly protein 1-like 2
chr9_-_86695897 2.054 ENSMUST00000034989.8
Me1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr3_+_146852359 2.029 ENSMUST00000038090.5
ENSMUST00000170055.1
Ttll7

tubulin tyrosine ligase-like family, member 7

chr16_+_17561885 2.007 ENSMUST00000171002.1
ENSMUST00000023441.4
P2rx6

purinergic receptor P2X, ligand-gated ion channel, 6

chr6_+_5725812 1.967 ENSMUST00000115554.1
ENSMUST00000153942.1
Dync1i1

dynein cytoplasmic 1 intermediate chain 1

chr17_-_56133817 1.889 ENSMUST00000167545.1
Sema6b
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr2_+_156475803 1.851 ENSMUST00000029155.8
Epb4.1l1
erythrocyte protein band 4.1-like 1
chrX_+_163911401 1.808 ENSMUST00000140845.1
Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr2_+_156475844 1.757 ENSMUST00000103135.1
Epb4.1l1
erythrocyte protein band 4.1-like 1
chr1_-_134235420 1.723 ENSMUST00000038191.6
ENSMUST00000086465.4
Adora1

adenosine A1 receptor

chrX_+_6047453 1.637 ENSMUST00000103007.3
Nudt11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr2_+_118663235 1.627 ENSMUST00000099557.3
Pak6
p21 protein (Cdc42/Rac)-activated kinase 6
chr19_-_8839181 1.609 ENSMUST00000096259.4
Gng3
guanine nucleotide binding protein (G protein), gamma 3
chr11_+_103171081 1.539 ENSMUST00000042286.5
Fmnl1
formin-like 1
chr3_-_116968827 1.532 ENSMUST00000119557.1
Palmd
palmdelphin
chr16_+_18812286 1.493 ENSMUST00000005394.6
Ufd1l
ubiquitin fusion degradation 1 like
chr8_+_125995102 1.493 ENSMUST00000046765.8
Kcnk1
potassium channel, subfamily K, member 1
chr6_-_13838432 1.476 ENSMUST00000115492.1
Gpr85
G protein-coupled receptor 85
chr1_-_79440039 1.439 ENSMUST00000049972.4
Scg2
secretogranin II
chr11_-_50210765 1.420 ENSMUST00000143379.1
ENSMUST00000015981.5
ENSMUST00000102774.4
Sqstm1


sequestosome 1


chr15_+_84669565 1.395 ENSMUST00000171460.1
Prr5
proline rich 5 (renal)
chr2_-_32353247 1.389 ENSMUST00000078352.5
ENSMUST00000113352.2
ENSMUST00000113365.1
Dnm1


dynamin 1


chr16_+_20694908 1.354 ENSMUST00000056518.6
Fam131a
family with sequence similarity 131, member A
chr10_-_116473418 1.309 ENSMUST00000087965.4
ENSMUST00000164271.1
Kcnmb4

potassium large conductance calcium-activated channel, subfamily M, beta member 4

chr19_+_26753588 1.298 ENSMUST00000177116.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr1_+_136131382 1.288 ENSMUST00000075164.4
Kif21b
kinesin family member 21B
chr10_+_116143881 1.288 ENSMUST00000105271.2
Ptprr
protein tyrosine phosphatase, receptor type, R
chr2_-_102400863 1.270 ENSMUST00000102573.1
Trim44
tripartite motif-containing 44
chr5_-_92348871 1.266 ENSMUST00000038816.6
ENSMUST00000118006.1
Cxcl10

chemokine (C-X-C motif) ligand 10

chr6_-_124769548 1.250 ENSMUST00000149652.1
ENSMUST00000112476.1
ENSMUST00000004378.8
Eno2


enolase 2, gamma neuronal


chr5_+_34525797 1.249 ENSMUST00000125817.1
ENSMUST00000067638.7
Sh3bp2

SH3-domain binding protein 2

chrX_+_159840463 1.242 ENSMUST00000112451.1
ENSMUST00000112453.2
Sh3kbp1

SH3-domain kinase binding protein 1

chr12_+_111758923 1.219 ENSMUST00000118471.1
ENSMUST00000122300.1
Klc1

kinesin light chain 1

chr2_+_180042496 1.198 ENSMUST00000041126.8
Ss18l1
synovial sarcoma translocation gene on chromosome 18-like 1
chr9_+_32224246 1.185 ENSMUST00000168954.2
Arhgap32
Rho GTPase activating protein 32
chr9_+_32224457 1.090 ENSMUST00000183121.1
Arhgap32
Rho GTPase activating protein 32
chr19_+_26623419 1.079 ENSMUST00000176584.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr7_+_4460687 1.078 ENSMUST00000167298.1
ENSMUST00000171445.1
Eps8l1

EPS8-like 1

chr11_-_97500340 1.076 ENSMUST00000056955.1
4933428G20Rik
RIKEN cDNA 4933428G20 gene
chr18_+_67133713 1.072 ENSMUST00000076605.7
Gnal
guanine nucleotide binding protein, alpha stimulating, olfactory type
chr18_+_37955544 1.046 ENSMUST00000070709.2
ENSMUST00000177058.1
ENSMUST00000169360.2
ENSMUST00000163591.2
ENSMUST00000091932.5
Rell2




RELT-like 2




chr1_-_173367638 1.000 ENSMUST00000005470.4
ENSMUST00000111220.1
Cadm3

cell adhesion molecule 3

chr9_+_58823512 0.990 ENSMUST00000034889.8
Hcn4
hyperpolarization-activated, cyclic nucleotide-gated K+ 4
chr2_-_84886692 0.985 ENSMUST00000054514.5
ENSMUST00000151799.1
Rtn4rl2

reticulon 4 receptor-like 2

chr9_-_112217261 0.984 ENSMUST00000159451.1
ENSMUST00000162796.1
ENSMUST00000161097.1
Arpp21


cyclic AMP-regulated phosphoprotein, 21


chr7_-_109781538 0.943 ENSMUST00000033331.6
Nrip3
nuclear receptor interacting protein 3
chr18_-_43059418 0.928 ENSMUST00000025377.7
Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr10_-_116473875 0.924 ENSMUST00000068233.4
Kcnmb4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr7_-_75308373 0.905 ENSMUST00000085164.5
Sv2b
synaptic vesicle glycoprotein 2 b
chr6_-_129533267 0.904 ENSMUST00000181594.1
1700101I11Rik
RIKEN cDNA 1700101I11 gene
chr19_+_8839298 0.902 ENSMUST00000160556.1
Bscl2
Bernardinelli-Seip congenital lipodystrophy 2 homolog (human)
chr2_+_164948219 0.900 ENSMUST00000017881.2
Mmp9
matrix metallopeptidase 9
chr2_-_104257400 0.896 ENSMUST00000141159.1
D430041D05Rik
RIKEN cDNA D430041D05 gene
chr12_+_111758848 0.895 ENSMUST00000084941.5
Klc1
kinesin light chain 1
chr5_-_115652974 0.877 ENSMUST00000121746.1
ENSMUST00000118576.1
Ccdc64

coiled-coil domain containing 64

chr2_+_32628390 0.874 ENSMUST00000156578.1
Ak1
adenylate kinase 1
chr13_+_29014399 0.873 ENSMUST00000146336.1
ENSMUST00000130109.1
A330102I10Rik

RIKEN cDNA A330102I10 gene

chrX_-_95196450 0.873 ENSMUST00000181987.1
Arhgef9
CDC42 guanine nucleotide exchange factor (GEF) 9
chr10_+_128933782 0.872 ENSMUST00000099112.2
Itga7
integrin alpha 7
chr1_+_33908172 0.865 ENSMUST00000182513.1
ENSMUST00000183034.1
Dst

dystonin

chr11_-_48871408 0.846 ENSMUST00000097271.2
Irgm1
immunity-related GTPase family M member 1
chr9_-_50739365 0.843 ENSMUST00000117093.1
ENSMUST00000121634.1
Dixdc1

DIX domain containing 1

chr2_-_30124454 0.843 ENSMUST00000044751.8
Zer1
zyg-11 related, cell cycle regulator
chrX_-_167209149 0.816 ENSMUST00000112176.1
Tmsb4x
thymosin, beta 4, X chromosome
chrX_+_74424534 0.810 ENSMUST00000135165.1
ENSMUST00000114128.1
ENSMUST00000114133.2
ENSMUST00000004330.3
Ikbkg



inhibitor of kappaB kinase gamma



chr14_-_37135126 0.806 ENSMUST00000042564.9
Ghitm
growth hormone inducible transmembrane protein
chrX_+_93675088 0.803 ENSMUST00000045898.3
Pcyt1b
phosphate cytidylyltransferase 1, choline, beta isoform
chr2_+_4300462 0.793 ENSMUST00000175669.1
Frmd4a
FERM domain containing 4A
chr18_+_37955685 0.784 ENSMUST00000169498.2
Rell2
RELT-like 2
chr6_-_41636389 0.759 ENSMUST00000031902.5
Trpv6
transient receptor potential cation channel, subfamily V, member 6
chr10_+_60277627 0.757 ENSMUST00000105465.1
ENSMUST00000177779.1
ENSMUST00000179238.1
ENSMUST00000004316.8
Psap



prosaposin



chr1_+_125676969 0.755 ENSMUST00000027581.6
Gpr39
G protein-coupled receptor 39
chr4_-_136886187 0.747 ENSMUST00000046384.8
C1qb
complement component 1, q subcomponent, beta polypeptide
chr2_-_30124529 0.738 ENSMUST00000113677.1
Zer1
zyg-11 related, cell cycle regulator
chr17_-_24644933 0.729 ENSMUST00000019684.5
Slc9a3r2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chrX_-_136868537 0.724 ENSMUST00000058814.6
Rab9b
RAB9B, member RAS oncogene family
chr16_-_18343882 0.722 ENSMUST00000130752.1
ENSMUST00000115628.2
Tango2

transport and golgi organization 2

chr2_-_163419508 0.710 ENSMUST00000046908.3
Oser1
oxidative stress responsive serine rich 1
chrX_+_152178945 0.704 ENSMUST00000096275.4
Iqsec2
IQ motif and Sec7 domain 2
chr14_-_20794009 0.696 ENSMUST00000100837.3
ENSMUST00000080440.6
ENSMUST00000071816.6
Camk2g


calcium/calmodulin-dependent protein kinase II gamma


chr4_+_43406435 0.676 ENSMUST00000098106.2
ENSMUST00000139198.1
Rusc2

RUN and SH3 domain containing 2

chrX_+_152144240 0.675 ENSMUST00000168786.1
ENSMUST00000112605.1
ENSMUST00000112604.1
Iqsec2


IQ motif and Sec7 domain 2


chrX_+_74424632 0.668 ENSMUST00000114129.2
ENSMUST00000132749.1
Ikbkg

inhibitor of kappaB kinase gamma

chr7_-_30362772 0.668 ENSMUST00000046351.5
Lrfn3
leucine rich repeat and fibronectin type III domain containing 3
chr6_+_124996681 0.667 ENSMUST00000032479.4
Pianp
PILR alpha associated neural protein
chr11_+_31872100 0.662 ENSMUST00000020543.6
ENSMUST00000109412.2
Cpeb4

cytoplasmic polyadenylation element binding protein 4

chr4_+_150855064 0.661 ENSMUST00000030811.1
Errfi1
ERBB receptor feedback inhibitor 1
chr5_-_38159457 0.655 ENSMUST00000031009.4
Nsg1
neuron specific gene family member 1
chr15_+_102503722 0.650 ENSMUST00000096145.4
Gm10337
predicted gene 10337
chr13_-_12461432 0.632 ENSMUST00000143693.1
ENSMUST00000144283.1
ENSMUST00000099820.3
ENSMUST00000135166.1
Lgals8



lectin, galactose binding, soluble 8



chr6_+_51523901 0.632 ENSMUST00000049152.8
Snx10
sorting nexin 10
chr11_-_76509419 0.626 ENSMUST00000094012.4
Abr
active BCR-related gene
chr15_-_100599864 0.619 ENSMUST00000177247.2
ENSMUST00000177505.2
Pou6f1

POU domain, class 6, transcription factor 1

chr2_-_44927161 0.617 ENSMUST00000130991.1
Gtdc1
glycosyltransferase-like domain containing 1
chr5_+_19907774 0.613 ENSMUST00000115267.2
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr3_-_84220853 0.610 ENSMUST00000154152.1
ENSMUST00000107693.2
ENSMUST00000107695.2
Trim2


tripartite motif-containing 2


chr6_-_56901870 0.607 ENSMUST00000101367.2
Nt5c3
5'-nucleotidase, cytosolic III
chr2_+_25428699 0.599 ENSMUST00000102919.3
Abca2
ATP-binding cassette, sub-family A (ABC1), member 2
chrX_-_122397351 0.592 ENSMUST00000079490.4
Nap1l3
nucleosome assembly protein 1-like 3
chr3_-_95228636 0.590 ENSMUST00000065482.5
Mllt11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr18_-_33463615 0.581 ENSMUST00000051087.8
Nrep
neuronal regeneration related protein
chr16_+_11405648 0.580 ENSMUST00000096273.2
Snx29
sorting nexin 29
chr12_+_35047180 0.579 ENSMUST00000048519.9
ENSMUST00000163677.1
Snx13

sorting nexin 13

chr14_-_37135310 0.571 ENSMUST00000165649.2
Ghitm
growth hormone inducible transmembrane protein
chrX_+_7822289 0.570 ENSMUST00000009875.4
Kcnd1
potassium voltage-gated channel, Shal-related family, member 1
chr10_+_18845071 0.568 ENSMUST00000019998.7
Perp
PERP, TP53 apoptosis effector
chr7_-_68749170 0.559 ENSMUST00000118110.1
ENSMUST00000048068.7
Arrdc4

arrestin domain containing 4

chr15_+_76380492 0.558 ENSMUST00000096385.4
ENSMUST00000160728.1
ENSMUST00000162319.1
Mroh1


maestro heat-like repeat family member 1


chr9_-_112217344 0.555 ENSMUST00000161412.1
Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr2_+_25395866 0.553 ENSMUST00000028328.2
Entpd2
ectonucleoside triphosphate diphosphohydrolase 2
chr3_-_116968969 0.541 ENSMUST00000143611.1
ENSMUST00000040097.7
Palmd

palmdelphin

chr17_+_55952623 0.537 ENSMUST00000003274.6
Ebi3
Epstein-Barr virus induced gene 3
chr2_-_20943413 0.525 ENSMUST00000140230.1
Arhgap21
Rho GTPase activating protein 21
chr10_-_62899118 0.522 ENSMUST00000174189.1
Tet1
tet methylcytosine dioxygenase 1
chr18_+_61639542 0.507 ENSMUST00000183083.1
ENSMUST00000183087.1
Gm20748

predicted gene, 20748

chr19_+_57611020 0.505 ENSMUST00000077282.5
Atrnl1
attractin like 1
chr1_+_173673651 0.504 ENSMUST00000085876.4
Pydc3
pyrin domain containing 3
chr5_+_30814722 0.497 ENSMUST00000114724.1
Mapre3
microtubule-associated protein, RP/EB family, member 3
chr2_+_28533355 0.496 ENSMUST00000113893.1
ENSMUST00000100241.3
Ralgds

ral guanine nucleotide dissociation stimulator

chr16_-_32868325 0.496 ENSMUST00000089684.3
ENSMUST00000040986.8
ENSMUST00000115105.2
1700021K19Rik


RIKEN cDNA 1700021K19 gene


chr7_-_44670820 0.495 ENSMUST00000048102.7
Myh14
myosin, heavy polypeptide 14
chr5_+_30814571 0.492 ENSMUST00000031058.8
Mapre3
microtubule-associated protein, RP/EB family, member 3
chr15_-_100599983 0.487 ENSMUST00000073837.6
Pou6f1
POU domain, class 6, transcription factor 1
chr11_+_87592145 0.486 ENSMUST00000103179.3
ENSMUST00000092802.5
ENSMUST00000146871.1
Mtmr4


myotubularin related protein 4


chr18_-_33464007 0.475 ENSMUST00000168890.1
Nrep
neuronal regeneration related protein
chr4_+_102421518 0.474 ENSMUST00000106904.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr13_-_113663670 0.467 ENSMUST00000054650.4
Hspb3
heat shock protein 3
chr12_+_111538101 0.466 ENSMUST00000166123.1
Eif5
eukaryotic translation initiation factor 5
chr15_+_3270767 0.464 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
Sepp1



selenoprotein P, plasma, 1



chr11_-_118355496 0.462 ENSMUST00000017610.3
Timp2
tissue inhibitor of metalloproteinase 2
chr14_+_26514554 0.460 ENSMUST00000104927.1
Gm2178
predicted gene 2178
chr8_+_109778863 0.457 ENSMUST00000034171.8
Ap1g1
adaptor protein complex AP-1, gamma 1 subunit
chr7_-_113347273 0.452 ENSMUST00000117577.1
Btbd10
BTB (POZ) domain containing 10
chr8_+_109778554 0.444 ENSMUST00000093157.6
Ap1g1
adaptor protein complex AP-1, gamma 1 subunit
chr11_-_98438941 0.441 ENSMUST00000002655.7
Mien1
migration and invasion enhancer 1
chr13_-_58215615 0.430 ENSMUST00000058735.5
ENSMUST00000076454.6
Ubqln1

ubiquilin 1

chr5_+_19907502 0.424 ENSMUST00000101558.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chrX_+_153498202 0.424 ENSMUST00000060714.8
Ubqln2
ubiquilin 2
chr19_-_53464721 0.422 ENSMUST00000180489.1
5830416P10Rik
RIKEN cDNA 5830416P10 gene
chr18_-_37969742 0.417 ENSMUST00000166148.1
ENSMUST00000163131.1
ENSMUST00000043437.7
Fchsd1


FCH and double SH3 domains 1


chr2_-_9878580 0.415 ENSMUST00000102976.3
Gata3
GATA binding protein 3
chr5_+_138116903 0.393 ENSMUST00000062350.8
ENSMUST00000110961.2
ENSMUST00000080732.3
ENSMUST00000110960.2
ENSMUST00000142185.1
ENSMUST00000136425.1
ENSMUST00000110959.1
Zscan21






zinc finger and SCAN domain containing 21






chr16_-_76373827 0.392 ENSMUST00000121927.1
Nrip1
nuclear receptor interacting protein 1
chr5_+_43233463 0.390 ENSMUST00000169035.1
ENSMUST00000166713.1
Cpeb2

cytoplasmic polyadenylation element binding protein 2

chr14_+_20694956 0.387 ENSMUST00000048016.1
Fut11
fucosyltransferase 11
chr11_+_82101836 0.384 ENSMUST00000000194.3
Ccl12
chemokine (C-C motif) ligand 12
chr8_+_107293500 0.380 ENSMUST00000151114.1
ENSMUST00000075922.4
ENSMUST00000125721.1
Nfat5


nuclear factor of activated T cells 5


chr4_+_141793612 0.378 ENSMUST00000097805.4
ENSMUST00000030747.4
ENSMUST00000153094.1
Casp9


caspase 9


chr8_+_25532125 0.373 ENSMUST00000167764.1
Fgfr1
fibroblast growth factor receptor 1
chr1_+_127306706 0.372 ENSMUST00000171405.1
Mgat5
mannoside acetylglucosaminyltransferase 5
chr9_-_63399216 0.372 ENSMUST00000168665.1
2300009A05Rik
RIKEN cDNA 2300009A05 gene
chr14_-_21848924 0.370 ENSMUST00000124549.1
Comtd1
catechol-O-methyltransferase domain containing 1
chr5_+_66676098 0.370 ENSMUST00000031131.9
Uchl1
ubiquitin carboxy-terminal hydrolase L1
chr8_+_123332676 0.368 ENSMUST00000010298.6
Spire2
spire homolog 2 (Drosophila)
chr12_+_88360535 0.368 ENSMUST00000101165.2
Adck1
aarF domain containing kinase 1
chr11_+_87592897 0.366 ENSMUST00000119628.1
Mtmr4
myotubularin related protein 4
chr5_+_43233928 0.364 ENSMUST00000114066.1
ENSMUST00000114065.1
Cpeb2

cytoplasmic polyadenylation element binding protein 2

chrX_+_73675500 0.364 ENSMUST00000171398.1
Slc6a8
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr6_+_17463927 0.363 ENSMUST00000115442.1
Met
met proto-oncogene
chr11_+_87582201 0.362 ENSMUST00000133202.1
Sept4
septin 4
chr11_+_60728398 0.359 ENSMUST00000018743.4
Mief2
mitochondrial elongation factor 2
chr1_-_30949756 0.353 ENSMUST00000076587.3
ENSMUST00000027232.7
Ptp4a1

protein tyrosine phosphatase 4a1

chr5_-_108675569 0.350 ENSMUST00000051757.7
Slc26a1
solute carrier family 26 (sulfate transporter), member 1
chr7_-_44849075 0.348 ENSMUST00000047085.8
Tbc1d17
TBC1 domain family, member 17
chr6_+_17463749 0.348 ENSMUST00000115443.1
Met
met proto-oncogene
chr11_-_54962903 0.348 ENSMUST00000108885.1
ENSMUST00000102730.2
ENSMUST00000018482.6
ENSMUST00000108886.1
ENSMUST00000102731.1
Tnip1




TNFAIP3 interacting protein 1




chr11_-_48871344 0.340 ENSMUST00000049519.3
Irgm1
immunity-related GTPase family M member 1
chr8_-_126945841 0.335 ENSMUST00000179857.1
Tomm20
translocase of outer mitochondrial membrane 20 homolog (yeast)
chr2_-_120850389 0.333 ENSMUST00000143051.1
ENSMUST00000057135.7
ENSMUST00000085840.4
Ttbk2


tau tubulin kinase 2


chr12_+_70974621 0.333 ENSMUST00000160027.1
ENSMUST00000160864.1
Psma3

proteasome (prosome, macropain) subunit, alpha type 3

chr9_-_44320229 0.333 ENSMUST00000065080.8
C2cd2l
C2 calcium-dependent domain containing 2-like
chr2_-_120850598 0.331 ENSMUST00000028740.4
Ttbk2
tau tubulin kinase 2
chr10_+_80264942 0.327 ENSMUST00000105362.1
ENSMUST00000105361.3
Dazap1

DAZ associated protein 1

chr7_+_49759100 0.326 ENSMUST00000085272.5
Htatip2
HIV-1 tat interactive protein 2, homolog (human)
chr5_+_25247344 0.316 ENSMUST00000114950.1
Galnt11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11
chr2_-_156392829 0.315 ENSMUST00000088578.2
2900097C17Rik
RIKEN cDNA 2900097C17 gene
chr15_-_102257449 0.313 ENSMUST00000043172.8
Rarg
retinoic acid receptor, gamma
chr7_+_19359740 0.311 ENSMUST00000140836.1
Ppp1r13l
protein phosphatase 1, regulatory (inhibitor) subunit 13 like
chrX_+_162901567 0.310 ENSMUST00000112303.1
ENSMUST00000033727.7
Ctps2

cytidine 5'-triphosphate synthase 2

chr9_-_122310921 0.307 ENSMUST00000180685.1
Gm26797
predicted gene, 26797
chr10_+_79996479 0.303 ENSMUST00000132517.1
Abca7
ATP-binding cassette, sub-family A (ABC1), member 7
chr7_-_110862944 0.302 ENSMUST00000033050.3
Lyve1
lymphatic vessel endothelial hyaluronan receptor 1
chr11_-_69805617 0.295 ENSMUST00000051025.4
Tmem102
transmembrane protein 102
chr2_+_163995503 0.294 ENSMUST00000131288.1
Ywhab
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
chr9_-_21239310 0.290 ENSMUST00000164812.1
ENSMUST00000049567.4
Keap1

kelch-like ECH-associated protein 1

chr2_-_120850364 0.287 ENSMUST00000131389.1
Ttbk2
tau tubulin kinase 2
chr11_-_120630516 0.285 ENSMUST00000106181.1
Mafg
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr13_-_12106945 0.284 ENSMUST00000021750.7
ENSMUST00000170156.2
Ryr2

ryanodine receptor 2, cardiac

chr3_-_31310349 0.282 ENSMUST00000091259.2
Slc7a14
solute carrier family 7 (cationic amino acid transporter, y+ system), member 14
chr5_-_124187150 0.282 ENSMUST00000161938.1
Pitpnm2
phosphatidylinositol transfer protein, membrane-associated 2
chr17_+_15053059 0.282 ENSMUST00000040594.8
Ermard
ER membrane associated RNA degradation

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 9.8 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.6 1.7 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.4 2.6 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.4 2.1 GO:0035617 stress granule disassembly(GO:0035617)
0.4 2.1 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.4 5.7 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.4 3.1 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.3 0.7 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.3 1.3 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.3 1.3 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.3 4.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.3 2.5 GO:0005513 detection of calcium ion(GO:0005513)
0.3 1.5 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.3 0.9 GO:0043323 positive regulation of natural killer cell degranulation(GO:0043323)
0.3 1.2 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.3 1.6 GO:1901911 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.3 2.4 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.3 0.8 GO:0035482 gastric motility(GO:0035482) gastric emptying(GO:0035483) negative regulation of gastric acid secretion(GO:0060455)
0.2 1.5 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.2 1.0 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.2 1.0 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.2 2.0 GO:0018095 protein polyglutamylation(GO:0018095)
0.2 1.0 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.2 1.4 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.2 1.1 GO:0009405 pathogenesis(GO:0009405)
0.2 1.8 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.2 1.4 GO:0061635 regulation of protein complex stability(GO:0061635)
0.2 1.4 GO:0038203 TORC2 signaling(GO:0038203)
0.2 1.1 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.2 1.5 GO:0051014 actin filament severing(GO:0051014)
0.2 6.1 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 0.9 GO:0046103 ADP biosynthetic process(GO:0006172) inosine biosynthetic process(GO:0046103)
0.1 0.1 GO:2000468 regulation of peroxidase activity(GO:2000468)
0.1 0.6 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.1 0.4 GO:0034140 negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) aggrephagy(GO:0035973)
0.1 0.4 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.1 0.4 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 1.0 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.1 0.4 GO:2000501 natural killer cell chemotaxis(GO:0035747) negative regulation of lymphocyte migration(GO:2000402) regulation of natural killer cell chemotaxis(GO:2000501)
0.1 0.6 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.1 0.4 GO:0021837 motogenic signaling involved in postnatal olfactory bulb interneuron migration(GO:0021837) positive regulation of mitotic cell cycle DNA replication(GO:1903465)
0.1 0.7 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.4 GO:0051295 establishment of meiotic spindle localization(GO:0051295) formin-nucleated actin cable assembly(GO:0070649)
0.1 0.3 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.1 0.8 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 1.5 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 0.6 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 0.5 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 0.5 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.1 0.6 GO:0002934 desmosome organization(GO:0002934)
0.1 2.6 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.1 0.4 GO:0007412 axon target recognition(GO:0007412)
0.1 0.3 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.1 0.4 GO:0035937 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.1 0.6 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.6 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 0.8 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 0.3 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.1 0.8 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1 0.2 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 2.0 GO:0033198 response to ATP(GO:0033198)
0.1 0.5 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.3 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 0.2 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.1 0.7 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 1.4 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.1 0.3 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.9 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1 0.6 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.1 0.8 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.1 0.7 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.1 0.6 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.1 1.0 GO:1990403 embryonic brain development(GO:1990403)
0.1 0.4 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 1.2 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.1 0.7 GO:0046036 CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036)
0.1 0.2 GO:2000189 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) positive regulation of cholesterol homeostasis(GO:2000189)
0.1 0.2 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1 0.4 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 0.4 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.1 0.9 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.4 GO:0019532 oxalate transport(GO:0019532)
0.0 0.3 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.0 3.7 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.0 0.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.3 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.2 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.2 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.5 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.3 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 0.3 GO:0015862 uridine transport(GO:0015862)
0.0 0.7 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.2 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 2.1 GO:0051438 regulation of ubiquitin-protein transferase activity(GO:0051438)
0.0 0.3 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.0 0.8 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.7 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.2 GO:0007603 phototransduction, visible light(GO:0007603)
0.0 0.1 GO:0035247 peptidyl-arginine omega-N-methylation(GO:0035247)
0.0 0.1 GO:2000195 negative regulation of female gonad development(GO:2000195)
0.0 0.5 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.5 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.0 0.3 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 1.0 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.0 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0 0.4 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.6 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.4 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.0 0.8 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.0 0.2 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.1 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.1 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 1.8 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:1903347 cellular response to testosterone stimulus(GO:0071394) negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.9 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 1.5 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 1.1 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 0.1 GO:0034773 histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.0 0.5 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 3.3 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.1 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.4 GO:0072337 modified amino acid transport(GO:0072337)
0.0 0.2 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.0 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.1 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.0 0.3 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.2 GO:0070536 protein K63-linked deubiquitination(GO:0070536)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 9.8 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
0.8 3.1 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.5 1.4 GO:0044753 amphisome(GO:0044753)
0.4 4.9 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.4 1.5 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.3 1.0 GO:0098855 HCN channel complex(GO:0098855)
0.3 4.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.3 0.9 GO:0005927 muscle tendon junction(GO:0005927)
0.2 0.9 GO:0031673 H zone(GO:0031673)
0.1 3.6 GO:0071565 nBAF complex(GO:0071565)
0.1 1.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 2.1 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 1.6 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 1.0 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 1.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 0.3 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 0.9 GO:0001520 outer dense fiber(GO:0001520)
0.1 2.1 GO:0035253 ciliary rootlet(GO:0035253)
0.1 1.2 GO:0044754 autolysosome(GO:0044754)
0.1 0.4 GO:0043293 apoptosome(GO:0043293)
0.1 1.4 GO:0031932 TORC2 complex(GO:0031932)
0.1 1.4 GO:0043196 varicosity(GO:0043196)
0.1 0.5 GO:0097513 myosin II filament(GO:0097513)
0.1 1.7 GO:0032279 asymmetric synapse(GO:0032279)
0.1 2.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.2 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.1 0.6 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 1.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 2.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.7 GO:0098845 postsynaptic endosome(GO:0098845)
0.1 0.5 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.8 GO:0031045 dense core granule(GO:0031045)
0.0 0.4 GO:0097227 sperm annulus(GO:0097227)
0.0 2.3 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.2 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 2.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 1.0 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 2.7 GO:0030117 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.0 3.0 GO:0005604 basement membrane(GO:0005604)
0.0 1.0 GO:0035371 microtubule plus-end(GO:0035371)
0.0 1.0 GO:0035869 ciliary transition zone(GO:0035869)
0.0 1.1 GO:0005871 kinesin complex(GO:0005871)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 3.2 GO:0001650 fibrillar center(GO:0001650)
0.0 0.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.7 GO:0032420 stereocilium(GO:0032420)
0.0 0.1 GO:1990357 terminal web(GO:1990357) HFE-transferrin receptor complex(GO:1990712)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 1.5 GO:0000502 proteasome complex(GO:0000502)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.7 GO:0005581 collagen trimer(GO:0005581)
0.0 0.9 GO:0030139 endocytic vesicle(GO:0030139)
0.0 1.3 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.4 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.9 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 1.0 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.2 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.6 GO:0043197 dendritic spine(GO:0043197)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.6 9.8 GO:0045504 dynein heavy chain binding(GO:0045504)
0.5 2.0 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.5 1.5 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.4 4.7 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.3 2.0 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.3 1.6 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.3 1.3 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.2 1.0 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.2 1.7 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609) heterotrimeric G-protein binding(GO:0032795)
0.2 0.7 GO:0003883 CTP synthase activity(GO:0003883)
0.2 0.7 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.2 1.0 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 6.2 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 0.8 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.2 0.8 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 2.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 1.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.4 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.1 1.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.6 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 1.8 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 0.9 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 3.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.3 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.4 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 0.4 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 0.3 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.1 1.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.4 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.1 0.4 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 0.4 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.5 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.4 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.9 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 1.4 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 0.5 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.4 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.2 GO:0030350 iron-responsive element binding(GO:0030350)
0.1 1.4 GO:0042056 chemoattractant activity(GO:0042056)
0.1 1.5 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 1.1 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 1.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 0.6 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.1 0.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 1.1 GO:0042608 T cell receptor binding(GO:0042608)
0.1 0.9 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 0.2 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.1 0.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 3.4 GO:0003777 microtubule motor activity(GO:0003777)
0.0 2.5 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.3 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 1.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.3 GO:0043559 insulin binding(GO:0043559)
0.0 0.9 GO:0043236 laminin binding(GO:0043236)
0.0 0.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 2.2 GO:0005518 collagen binding(GO:0005518)
0.0 0.3 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.0 4.4 GO:0000149 SNARE binding(GO:0000149)
0.0 0.1 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.9 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.6 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.5 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.4 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.0 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.1 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
0.0 1.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.8 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.6 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 1.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.7 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 1.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.7 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 5.7 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 1.0 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.7 GO:0019003 GDP binding(GO:0019003)
0.0 0.4 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.9 GO:0017022 myosin binding(GO:0017022)
0.0 0.6 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 1.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.9 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.4 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.3 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.8 GO:0005178 integrin binding(GO:0005178)
0.0 1.2 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 1.2 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.3 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.1 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.7 PID_ARF_3PATHWAY Arf1 pathway
0.1 2.9 PID_IL1_PATHWAY IL1-mediated signaling events
0.1 1.1 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.1 3.2 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 1.5 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.3 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.0 1.1 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.0 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.9 PID_IL27_PATHWAY IL27-mediated signaling events
0.0 2.0 PID_TCR_PATHWAY TCR signaling in naïve CD4+ T cells
0.0 1.7 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.0 PID_CXCR3_PATHWAY CXCR3-mediated signaling events
0.0 0.6 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 2.2 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 2.2 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 2.4 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 1.8 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 3.4 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.9 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 1.0 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.4 PID_CXCR4_PATHWAY CXCR4-mediated signaling events
0.0 0.4 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.4 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.0 0.9 PID_ATR_PATHWAY ATR signaling pathway
0.0 0.4 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.6 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 0.4 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.0 2.0 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.6 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.1 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.3 PID_AP1_PATHWAY AP-1 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.3 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.3 3.1 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.3 4.0 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.2 1.2 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.2 1.5 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 2.7 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.2 4.0 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 11.9 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.1 1.5 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 1.7 REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.1 1.4 REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 0.7 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 1.6 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 2.2 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.1 0.6 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.1 1.6 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.6 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 0.9 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 0.9 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.1 1.3 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.2 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.3 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.9 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.0 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME_SIGNALING_BY_ACTIVATED_POINT_MUTANTS_OF_FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.8 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 0.4 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.0 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.8 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.6 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.0 0.3 REACTOME_RAF_MAP_KINASE_CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.4 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 2.3 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.2 REACTOME_PHOSPHORYLATION_OF_THE_APC_C Genes involved in Phosphorylation of the APC/C
0.0 0.2 REACTOME_P38MAPK_EVENTS Genes involved in p38MAPK events
0.0 0.5 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.5 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events