Motif ID: Lhx2_Hoxc5

Z-value: 0.593

Transcription factors associated with Lhx2_Hoxc5:

Gene SymbolEntrez IDGene Name
Hoxc5 ENSMUSG00000022485.3 Hoxc5
Lhx2 ENSMUSG00000000247.5 Lhx2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Lhx2mm10_v2_chr2_+_38339258_383392810.163.3e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Lhx2_Hoxc5

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_85722474 2.967 ENSMUST00000119077.1
Fam160a1
family with sequence similarity 160, member A1
chrM_+_10167 2.756 ENSMUST00000082414.1
mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr5_-_106926245 2.239 ENSMUST00000117588.1
Hfm1
HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
chr13_+_44121167 2.004 ENSMUST00000163056.1
ENSMUST00000159595.1
Gm5083

predicted gene 5083

chrX_+_170009892 1.919 ENSMUST00000180251.1
Gm21887
predicted gene, 21887
chr5_-_62766153 1.690 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr1_-_24612700 1.636 ENSMUST00000088336.1
Gm10222
predicted gene 10222
chrM_+_9870 1.537 ENSMUST00000084013.1
mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr5_+_13398688 1.371 ENSMUST00000125629.1
Sema3a
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr1_+_170308802 1.249 ENSMUST00000056991.5
1700015E13Rik
RIKEN cDNA 1700015E13 gene
chr8_+_66386292 1.247 ENSMUST00000039540.5
ENSMUST00000110253.2
March1

membrane-associated ring finger (C3HC4) 1

chr1_+_58210397 1.203 ENSMUST00000040442.5
Aox4
aldehyde oxidase 4
chr2_-_180954620 1.196 ENSMUST00000139929.1
Nkain4
Na+/K+ transporting ATPase interacting 4
chr9_+_72958785 1.179 ENSMUST00000098567.2
ENSMUST00000034734.8
Dyx1c1

dyslexia susceptibility 1 candidate 1 homolog (human)

chr18_+_37435602 1.168 ENSMUST00000055495.5
Pcdhb12
protocadherin beta 12
chr6_-_118479237 1.163 ENSMUST00000161170.1
Zfp9
zinc finger protein 9
chr17_+_26715644 1.158 ENSMUST00000062519.7
ENSMUST00000144221.1
ENSMUST00000142539.1
ENSMUST00000151681.1
Crebrf



CREB3 regulatory factor



chr17_-_36032682 1.079 ENSMUST00000102678.4
H2-T23
histocompatibility 2, T region locus 23
chr17_+_17316078 1.015 ENSMUST00000105311.3
Gm6712
predicted gene 6712
chrY_+_90785442 1.002 ENSMUST00000177591.1
ENSMUST00000177671.1
ENSMUST00000179077.1
Erdr1


erythroid differentiation regulator 1


chr7_-_45103747 0.990 ENSMUST00000003512.7
Fcgrt
Fc receptor, IgG, alpha chain transporter
chr5_+_91517615 0.974 ENSMUST00000040576.9
Parm1
prostate androgen-regulated mucin-like protein 1
chr1_+_43730593 0.963 ENSMUST00000027217.8
1500015O10Rik
RIKEN cDNA 1500015O10 gene
chr11_+_109543694 0.952 ENSMUST00000106696.1
Arsg
arylsulfatase G
chr14_+_69347587 0.937 ENSMUST00000064831.5
Entpd4
ectonucleoside triphosphate diphosphohydrolase 4
chr6_-_136875794 0.930 ENSMUST00000032342.1
Mgp
matrix Gla protein
chrM_+_11734 0.926 ENSMUST00000082418.1
mt-Nd5
mitochondrially encoded NADH dehydrogenase 5
chrX_+_73483602 0.906 ENSMUST00000033741.8
ENSMUST00000169489.1
Bgn

biglycan

chr4_+_147132038 0.877 ENSMUST00000084149.3
Gm13139
predicted gene 13139
chr6_+_116650674 0.868 ENSMUST00000067354.5
ENSMUST00000178241.1
8430408G22Rik

RIKEN cDNA 8430408G22 gene

chr2_-_114013619 0.839 ENSMUST00000090275.4
Gjd2
gap junction protein, delta 2
chr18_+_37355271 0.839 ENSMUST00000051163.1
Pcdhb8
protocadherin beta 8
chrM_+_2743 0.836 ENSMUST00000082392.1
mt-Nd1
mitochondrially encoded NADH dehydrogenase 1
chr10_+_75037066 0.816 ENSMUST00000147802.1
ENSMUST00000020391.5
Rab36

RAB36, member RAS oncogene family

chrX_+_103356464 0.815 ENSMUST00000116547.2
Chic1
cysteine-rich hydrophobic domain 1
chr2_-_160619971 0.767 ENSMUST00000109473.1
Gm14221
predicted gene 14221
chr1_+_115684727 0.764 ENSMUST00000043725.7
Cntnap5a
contactin associated protein-like 5A
chrY_+_90784738 0.761 ENSMUST00000179483.1
Erdr1
erythroid differentiation regulator 1
chr3_-_116712644 0.746 ENSMUST00000029569.2
Slc35a3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr16_+_18836573 0.743 ENSMUST00000055413.6
2510002D24Rik
RIKEN cDNA 2510002D24 gene
chr3_+_5218516 0.737 ENSMUST00000175866.1
Zfhx4
zinc finger homeodomain 4
chr9_+_80165079 0.731 ENSMUST00000184480.1
Myo6
myosin VI
chr10_-_18743691 0.725 ENSMUST00000019999.5
D10Bwg1379e
DNA segment, Chr 10, Brigham & Women's Genetics 1379 expressed
chr5_-_70842617 0.718 ENSMUST00000031119.1
Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr6_-_37442095 0.708 ENSMUST00000041093.5
Creb3l2
cAMP responsive element binding protein 3-like 2
chr10_-_33995054 0.693 ENSMUST00000164429.1
Gm17567
predicted gene, 17567
chrM_+_7759 0.684 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr4_+_146610961 0.684 ENSMUST00000130825.1
Gm13248
predicted gene 13248
chr4_+_43493345 0.643 ENSMUST00000030181.5
ENSMUST00000107922.2
Ccdc107

coiled-coil domain containing 107

chr9_+_25089422 0.642 ENSMUST00000086238.2
Gm10181
predicted gene 10181
chr10_-_86732409 0.627 ENSMUST00000070435.4
Fabp3-ps1
fatty acid binding protein 3, muscle and heart, pseudogene 1
chr16_+_96235801 0.626 ENSMUST00000113800.2
B3galt5
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5
chr4_-_155645408 0.619 ENSMUST00000115821.2
Gm10563
predicted gene 10563
chrM_+_7005 0.610 ENSMUST00000082405.1
mt-Co2
mitochondrially encoded cytochrome c oxidase II
chr4_+_147492417 0.600 ENSMUST00000105721.2
Gm13152
predicted gene 13152
chr10_-_128744014 0.592 ENSMUST00000026414.7
Dgka
diacylglycerol kinase, alpha
chr6_+_4003926 0.591 ENSMUST00000031670.8
Gng11
guanine nucleotide binding protein (G protein), gamma 11
chr6_-_57535422 0.584 ENSMUST00000042766.3
Ppm1k
protein phosphatase 1K (PP2C domain containing)
chr11_-_80377975 0.582 ENSMUST00000179332.1
ENSMUST00000103225.4
ENSMUST00000134274.1
5730455P16Rik


RIKEN cDNA 5730455P16 gene


chr6_-_101377342 0.581 ENSMUST00000151175.1
Pdzrn3
PDZ domain containing RING finger 3
chr7_-_5413145 0.577 ENSMUST00000108569.2
Vmn1r58
vomeronasal 1 receptor 58
chr13_+_76579670 0.568 ENSMUST00000126960.1
ENSMUST00000109583.2
Mctp1

multiple C2 domains, transmembrane 1

chr13_+_67833235 0.551 ENSMUST00000060609.7
Gm10037
predicted gene 10037
chr15_+_9436028 0.542 ENSMUST00000042360.3
Capsl
calcyphosine-like
chr3_-_113577743 0.540 ENSMUST00000067980.5
Amy1
amylase 1, salivary
chr2_+_3424123 0.529 ENSMUST00000061852.5
ENSMUST00000100463.3
ENSMUST00000102988.3
ENSMUST00000115066.1
Dclre1c



DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae)



chrX_+_170010744 0.527 ENSMUST00000178789.1
Gm21887
predicted gene, 21887
chr5_+_134932351 0.523 ENSMUST00000047196.7
ENSMUST00000111221.2
ENSMUST00000111219.1
ENSMUST00000068617.5
ENSMUST00000111218.1
ENSMUST00000136246.1
Wbscr27





Williams Beuren syndrome chromosome region 27 (human)





chr7_-_46672537 0.521 ENSMUST00000049298.7
Tph1
tryptophan hydroxylase 1
chrM_-_14060 0.520 ENSMUST00000082419.1
mt-Nd6
mitochondrially encoded NADH dehydrogenase 6
chr7_+_48959089 0.513 ENSMUST00000183659.1
Nav2
neuron navigator 2
chr10_-_56228636 0.504 ENSMUST00000099739.3
Tbc1d32
TBC1 domain family, member 32
chr13_-_105271039 0.497 ENSMUST00000069686.6
Rnf180
ring finger protein 180
chr9_+_75311395 0.491 ENSMUST00000076889.6
Gnb5
guanine nucleotide binding protein (G protein), beta 5
chr8_-_105966038 0.490 ENSMUST00000116429.2
ENSMUST00000034370.9
Slc12a4

solute carrier family 12, member 4

chr1_+_46066738 0.485 ENSMUST00000069293.7
Dnah7b
dynein, axonemal, heavy chain 7B
chr10_+_90071095 0.477 ENSMUST00000183109.1
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chrM_+_3906 0.476 ENSMUST00000082396.1
mt-Nd2
mitochondrially encoded NADH dehydrogenase 2
chr18_+_49832622 0.467 ENSMUST00000180611.1
Dmxl1
Dmx-like 1
chr6_-_122340525 0.458 ENSMUST00000112600.2
Phc1
polyhomeotic-like 1 (Drosophila)
chr9_-_37552904 0.454 ENSMUST00000065668.5
Nrgn
neurogranin
chr2_+_176711933 0.447 ENSMUST00000108983.2
Gm14305
predicted gene 14305
chrX_+_136741821 0.446 ENSMUST00000089350.4
BC065397
cDNA sequence BC065397
chr17_+_45555693 0.440 ENSMUST00000024742.7
Nfkbie
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon
chr17_-_57031468 0.438 ENSMUST00000007814.8
Khsrp
KH-type splicing regulatory protein
chr18_+_37411674 0.435 ENSMUST00000051126.2
Pcdhb10
protocadherin beta 10
chr4_+_145510759 0.434 ENSMUST00000105742.1
ENSMUST00000136309.1
Gm13225

predicted gene 13225

chrM_+_9452 0.432 ENSMUST00000082411.1
mt-Nd3
mitochondrially encoded NADH dehydrogenase 3
chr17_+_34931253 0.428 ENSMUST00000007253.5
Neu1
neuraminidase 1
chrX_+_163911401 0.422 ENSMUST00000140845.1
Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr11_+_116843278 0.422 ENSMUST00000106370.3
Mettl23
methyltransferase like 23
chr18_+_12741324 0.420 ENSMUST00000115857.2
ENSMUST00000121018.1
ENSMUST00000119108.1
Cabyr


calcium-binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2)


chr17_+_66111605 0.417 ENSMUST00000116556.2
Wash
WAS protein family homolog
chr3_-_116712696 0.414 ENSMUST00000169530.1
Slc35a3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr4_+_42035113 0.413 ENSMUST00000098127.1
Gm10597
predicted gene 10597
chr2_-_5063996 0.413 ENSMUST00000114996.1
Optn
optineurin
chr8_+_40354303 0.411 ENSMUST00000136835.1
Micu3
mitochondrial calcium uptake family, member 3
chr17_+_66111529 0.409 ENSMUST00000072383.6
Wash
WAS protein family homolog
chr11_-_102946688 0.401 ENSMUST00000057849.5
C1ql1
complement component 1, q subcomponent-like 1
chr9_-_85749308 0.393 ENSMUST00000039213.8
Ibtk
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr18_+_37484955 0.385 ENSMUST00000053856.4
Pcdhb17
protocadherin beta 17
chr13_+_83732438 0.385 ENSMUST00000182701.1
C130071C03Rik
RIKEN cDNA C130071C03 gene
chr10_-_83648631 0.384 ENSMUST00000146876.2
ENSMUST00000176294.1
Appl2

adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2

chrX_+_101449078 0.375 ENSMUST00000033674.5
Itgb1bp2
integrin beta 1 binding protein 2
chr12_+_16653470 0.375 ENSMUST00000111064.1
Ntsr2
neurotensin receptor 2
chr1_+_137966529 0.372 ENSMUST00000182158.1
A430106G13Rik
RIKEN cDNA A430106G13 gene
chr8_-_21906412 0.371 ENSMUST00000051965.4
Defb11
defensin beta 11
chrX_-_134111852 0.371 ENSMUST00000033610.6
Nox1
NADPH oxidase 1
chr2_+_125068118 0.364 ENSMUST00000070353.3
Slc24a5
solute carrier family 24, member 5
chr3_+_105973711 0.362 ENSMUST00000000573.2
Ovgp1
oviductal glycoprotein 1
chr5_-_43981757 0.357 ENSMUST00000061299.7
Fgfbp1
fibroblast growth factor binding protein 1
chr18_+_12972225 0.356 ENSMUST00000025290.5
Impact
imprinted and ancient
chr17_-_46327990 0.355 ENSMUST00000167360.1
Abcc10
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chr14_-_64455903 0.351 ENSMUST00000067927.7
Msra
methionine sulfoxide reductase A
chr5_-_48754521 0.349 ENSMUST00000101214.2
ENSMUST00000176191.1
Kcnip4

Kv channel interacting protein 4

chr5_+_107497718 0.344 ENSMUST00000112671.2
A830010M20Rik
RIKEN cDNA A830010M20 gene
chr9_+_118506226 0.344 ENSMUST00000084820.4
Golga4
golgi autoantigen, golgin subfamily a, 4
chr18_+_59062462 0.342 ENSMUST00000058633.2
ENSMUST00000175897.1
ENSMUST00000118510.1
ENSMUST00000175830.1
A730017C20Rik



RIKEN cDNA A730017C20 gene



chr13_+_75967704 0.342 ENSMUST00000022081.1
Spata9
spermatogenesis associated 9
chr1_+_16688405 0.340 ENSMUST00000026881.4
Ly96
lymphocyte antigen 96
chr15_+_82256023 0.340 ENSMUST00000143238.1
1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr2_-_130424673 0.340 ENSMUST00000110277.1
Pced1a
PC-esterase domain containing 1A
chr3_-_90389884 0.336 ENSMUST00000029541.5
Slc27a3
solute carrier family 27 (fatty acid transporter), member 3
chr17_+_35089229 0.329 ENSMUST00000007251.7
Abhd16a
abhydrolase domain containing 16A
chr18_+_61639542 0.326 ENSMUST00000183083.1
ENSMUST00000183087.1
Gm20748

predicted gene, 20748

chr9_-_96719404 0.324 ENSMUST00000140121.1
Zbtb38
zinc finger and BTB domain containing 38
chr6_+_145934113 0.322 ENSMUST00000032383.7
Sspn
sarcospan
chr4_+_146654927 0.321 ENSMUST00000070932.3
Gm13248
predicted gene 13248
chr12_+_116275386 0.318 ENSMUST00000090195.4
Gm11027
predicted gene 11027
chr15_-_89591855 0.315 ENSMUST00000094056.5
ENSMUST00000023294.8
Rabl2

RAB, member of RAS oncogene family-like 2

chr2_+_109917639 0.312 ENSMUST00000046548.7
ENSMUST00000111037.2
Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chr4_+_139923349 0.311 ENSMUST00000128563.1
Gm13028
predicted gene 13028
chr19_+_5088534 0.311 ENSMUST00000025811.4
Yif1a
Yip1 interacting factor homolog A (S. cerevisiae)
chr10_-_18227473 0.310 ENSMUST00000174592.1
Ccdc28a
coiled-coil domain containing 28A
chr12_-_75735729 0.304 ENSMUST00000021450.4
Sgpp1
sphingosine-1-phosphate phosphatase 1
chr19_+_55895508 0.300 ENSMUST00000111646.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr2_+_125136692 0.299 ENSMUST00000099452.2
Ctxn2
cortexin 2
chr10_+_40349265 0.296 ENSMUST00000044672.4
ENSMUST00000095743.2
Cdk19

cyclin-dependent kinase 19

chr10_-_81407641 0.296 ENSMUST00000140916.1
Nfic
nuclear factor I/C
chr14_+_101653967 0.289 ENSMUST00000002289.6
Uchl3
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr14_-_66124482 0.288 ENSMUST00000070515.1
Ephx2
epoxide hydrolase 2, cytoplasmic
chr8_-_123236198 0.288 ENSMUST00000166768.1
ENSMUST00000098327.1
Spata2l

spermatogenesis associated 2-like

chr17_-_46327949 0.288 ENSMUST00000047970.7
Abcc10
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chr13_+_23555023 0.287 ENSMUST00000045301.6
Hist1h1d
histone cluster 1, H1d
chr19_+_46761578 0.287 ENSMUST00000077666.4
ENSMUST00000099373.4
Cnnm2

cyclin M2

chr10_+_116143881 0.287 ENSMUST00000105271.2
Ptprr
protein tyrosine phosphatase, receptor type, R
chr5_-_109691041 0.285 ENSMUST00000092720.3
5430403G16Rik
RIKEN cDNA 5430403G16 gene
chr12_+_52699297 0.285 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chr2_+_154548888 0.284 ENSMUST00000045116.4
ENSMUST00000109709.3
1700003F12Rik

RIKEN cDNA 1700003F12 gene

chr4_-_116464151 0.284 ENSMUST00000106486.1
ENSMUST00000106485.1
Mast2

microtubule associated serine/threonine kinase 2

chr8_-_54724474 0.283 ENSMUST00000175915.1
Wdr17
WD repeat domain 17
chr3_-_57294880 0.283 ENSMUST00000171384.1
Tm4sf1
transmembrane 4 superfamily member 1
chr5_-_145201829 0.280 ENSMUST00000162220.1
ENSMUST00000031632.8
Zkscan14

zinc finger with KRAB and SCAN domains 14

chr11_+_32283511 0.277 ENSMUST00000093209.3
Hba-a1
hemoglobin alpha, adult chain 1
chr19_-_11604828 0.274 ENSMUST00000025582.4
Ms4a6d
membrane-spanning 4-domains, subfamily A, member 6D
chr3_+_107291215 0.271 ENSMUST00000029502.7
Slc16a4
solute carrier family 16 (monocarboxylic acid transporters), member 4
chr2_+_162931520 0.271 ENSMUST00000130411.1
Srsf6
serine/arginine-rich splicing factor 6
chr5_-_118244861 0.270 ENSMUST00000117177.1
ENSMUST00000133372.1
ENSMUST00000154786.1
ENSMUST00000121369.1
Rnft2



ring finger protein, transmembrane 2



chr2_-_161109017 0.267 ENSMUST00000039782.7
ENSMUST00000134178.1
Chd6

chromodomain helicase DNA binding protein 6

chr12_-_55821157 0.264 ENSMUST00000110687.1
ENSMUST00000085385.5
Ralgapa1

Ral GTPase activating protein, alpha subunit 1

chr10_+_116018213 0.260 ENSMUST00000063470.4
Ptprr
protein tyrosine phosphatase, receptor type, R
chr3_+_53845086 0.259 ENSMUST00000108014.1
Gm10985
predicted gene 10985
chr18_+_24470844 0.258 ENSMUST00000097646.3
2700062C07Rik
RIKEN cDNA 2700062C07 gene
chr2_-_136387929 0.255 ENSMUST00000035264.2
ENSMUST00000077200.3
Pak7

p21 protein (Cdc42/Rac)-activated kinase 7

chrX_-_150657366 0.255 ENSMUST00000148604.1
Tro
trophinin
chr4_+_42466752 0.254 ENSMUST00000179734.1
Gm2163
predicted gene 2163
chr7_+_79273201 0.252 ENSMUST00000037315.6
Abhd2
abhydrolase domain containing 2
chr10_+_70204675 0.251 ENSMUST00000020090.1
2310015B20Rik
RIKEN cDNA 2310015B20 gene
chr19_-_11818806 0.250 ENSMUST00000075304.6
Stx3
syntaxin 3
chrM_+_14138 0.250 ENSMUST00000082421.1
mt-Cytb
mitochondrially encoded cytochrome b
chr2_-_91950386 0.250 ENSMUST00000111303.1
Dgkz
diacylglycerol kinase zeta
chr6_-_28397999 0.249 ENSMUST00000035930.4
Zfp800
zinc finger protein 800
chr10_+_75037291 0.247 ENSMUST00000139384.1
Rab36
RAB36, member RAS oncogene family
chr4_+_147507600 0.242 ENSMUST00000063704.7
Gm13152
predicted gene 13152
chr4_-_41870612 0.241 ENSMUST00000179680.1
Gm21966
predicted gene, 21966
chr14_+_26259109 0.238 ENSMUST00000174494.1
Duxbl3
double homeobox B-like 3
chr19_-_44107447 0.237 ENSMUST00000119591.1
ENSMUST00000026217.4
Chuk

conserved helix-loop-helix ubiquitous kinase

chr17_-_45659312 0.235 ENSMUST00000120717.1
Capn11
calpain 11
chr7_-_19399859 0.233 ENSMUST00000047170.3
ENSMUST00000108459.2
Klc3

kinesin light chain 3

chr3_-_104220360 0.233 ENSMUST00000064371.7
Magi3
membrane associated guanylate kinase, WW and PDZ domain containing 3
chr9_-_14381242 0.229 ENSMUST00000167549.1
Endod1
endonuclease domain containing 1
chr1_+_97770158 0.227 ENSMUST00000112844.3
ENSMUST00000112842.1
ENSMUST00000027571.6
Gin1


gypsy retrotransposon integrase 1


chr2_+_65620829 0.227 ENSMUST00000028377.7
Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr4_+_116596672 0.227 ENSMUST00000051869.7
Ccdc17
coiled-coil domain containing 17
chr4_-_118489755 0.227 ENSMUST00000184261.1
Tie1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr6_+_134640940 0.225 ENSMUST00000062755.8
Loh12cr1
loss of heterozygosity, 12, chromosomal region 1 homolog (human)
chr4_-_42661893 0.224 ENSMUST00000108006.3
Il11ra2
interleukin 11 receptor, alpha chain 2
chr12_+_112760652 0.223 ENSMUST00000063888.3
Pld4
phospholipase D family, member 4
chr10_+_29143996 0.222 ENSMUST00000092629.2
Soga3
SOGA family member 3
chr9_-_15357692 0.220 ENSMUST00000098979.3
ENSMUST00000161132.1
5830418K08Rik

RIKEN cDNA 5830418K08 gene

chr14_-_76010863 0.219 ENSMUST00000088922.4
Gtf2f2
general transcription factor IIF, polypeptide 2
chr6_-_122340200 0.217 ENSMUST00000159384.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr6_-_122340499 0.217 ENSMUST00000160843.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr4_-_147809788 0.214 ENSMUST00000105734.3
ENSMUST00000176201.1
Gm13157
Gm20707
predicted gene 13157
predicted gene 20707
chr1_+_125676969 0.213 ENSMUST00000027581.6
Gpr39
G protein-coupled receptor 39
chr5_-_20882072 0.211 ENSMUST00000118174.1
Phtf2
putative homeodomain transcription factor 2
chr9_+_113812547 0.209 ENSMUST00000166734.2
ENSMUST00000111838.2
ENSMUST00000163895.2
Clasp2


CLIP associating protein 2


chr3_+_84952146 0.208 ENSMUST00000029727.7
Fbxw7
F-box and WD-40 domain protein 7
chr12_-_79007276 0.203 ENSMUST00000056660.6
ENSMUST00000174721.1
Tmem229b

transmembrane protein 229B

chr13_-_73678005 0.201 ENSMUST00000022105.7
ENSMUST00000109680.2
ENSMUST00000109679.2
Slc6a18


solute carrier family 6 (neurotransmitter transporter), member 18



Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0046110 xanthine metabolic process(GO:0046110)
0.4 1.1 GO:2000564 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.3 1.4 GO:0021856 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.2 1.2 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.2 1.2 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.2 2.2 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.2 3.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2 1.7 GO:0036159 inner dynein arm assembly(GO:0036159)
0.1 0.5 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 0.5 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.1 0.4 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 1.0 GO:0070314 G1 to G0 transition(GO:0070314)
0.1 1.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.4 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.1 0.3 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.1 0.3 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.1 0.4 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.1 0.3 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.1 0.4 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.4 GO:0061743 motor learning(GO:0061743)
0.1 0.2 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.1 0.3 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) olefin metabolic process(GO:1900673)
0.1 0.4 GO:0072592 regulation of integrin biosynthetic process(GO:0045113) oxygen metabolic process(GO:0072592)
0.1 0.4 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1 0.3 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.1 0.5 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.2 GO:0021886 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.1 3.5 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.1 0.2 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.1 0.3 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.1 1.2 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 0.3 GO:2000481 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
0.1 0.2 GO:0035482 gastric motility(GO:0035482) gastric emptying(GO:0035483) negative regulation of gastric acid secretion(GO:0060455)
0.1 0.8 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.1 0.3 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.1 0.3 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1 0.5 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 0.5 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.1 0.1 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.1 0.2 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 0.2 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.1 0.2 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.1 0.2 GO:0048296 isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296)
0.1 0.3 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.1 0.2 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 0.3 GO:0080184 response to stilbenoid(GO:0035634) response to phenylpropanoid(GO:0080184)
0.1 0.4 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.1 0.2 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.1 0.7 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.1 0.6 GO:0042428 serotonin metabolic process(GO:0042428)
0.0 0.1 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.5 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 0.1 GO:2000338 positive regulation of interleukin-23 production(GO:0032747) chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.0 0.4 GO:0042940 D-amino acid transport(GO:0042940)
0.0 0.2 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.2 GO:1903546 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108) protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.4 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.3 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334)
0.0 0.2 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.0 0.2 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667) regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.0 0.5 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.7 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.1 GO:0039533 regulation of MDA-5 signaling pathway(GO:0039533)
0.0 0.2 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.4 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.1 GO:0015793 glycerol transport(GO:0015793)
0.0 0.3 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.2 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.2 GO:0046208 spermine catabolic process(GO:0046208)
0.0 0.3 GO:0098967 synaptic vesicle docking(GO:0016081) exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.2 GO:0072338 creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.0 0.7 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.2 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.0 0.1 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.2 GO:1902741 type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.0 0.1 GO:0045006 DNA deamination(GO:0045006)
0.0 0.1 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.2 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.2 GO:0051461 corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.1 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
0.0 0.7 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.2 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.6 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.0 0.1 GO:0061622 glycolytic process through glucose-1-phosphate(GO:0061622)
0.0 0.1 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.0 0.1 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.0 0.2 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.2 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.1 GO:0060576 regulation of microvillus assembly(GO:0032534) intestinal epithelial cell development(GO:0060576)
0.0 0.0 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.1 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.8 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.1 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.2 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187) circadian sleep/wake cycle, sleep(GO:0050802)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.2 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.0 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0 0.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.9 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 0.4 GO:0071385 cellular response to glucocorticoid stimulus(GO:0071385)
0.0 0.4 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.0 GO:0009838 abscission(GO:0009838) positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.0 GO:1905034 regulation of antifungal innate immune response(GO:1905034) negative regulation of antifungal innate immune response(GO:1905035)
0.0 0.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.1 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.0 0.1 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.0 GO:1903406 regulation of sodium:potassium-exchanging ATPase activity(GO:1903406)
0.0 0.0 GO:0046077 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.0 0.1 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.0 0.6 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.0 0.2 GO:0006953 acute-phase response(GO:0006953)
0.0 0.6 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.2 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.1 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.1 GO:0044144 regulation of growth of symbiont in host(GO:0044126) modulation of growth of symbiont involved in interaction with host(GO:0044144)
0.0 0.3 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
0.0 0.2 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 1.1 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.3 GO:0042755 eating behavior(GO:0042755)
0.0 0.2 GO:0008206 bile acid metabolic process(GO:0008206)
0.0 1.1 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.4 GO:0008542 visual learning(GO:0008542)
0.0 0.3 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.1 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.2 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0097637 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.2 0.5 GO:0036156 inner dynein arm(GO:0036156)
0.1 8.2 GO:0070469 respiratory chain(GO:0070469)
0.1 0.4 GO:0071438 invadopodium membrane(GO:0071438)
0.1 1.1 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.9 GO:0001739 sex chromatin(GO:0001739)
0.1 0.4 GO:0044301 climbing fiber(GO:0044301)
0.1 1.0 GO:0005922 connexon complex(GO:0005922)
0.1 0.3 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 1.0 GO:0031045 dense core granule(GO:0031045)
0.1 0.2 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 0.6 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.1 0.2 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.3 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.0 0.4 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.2 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 0.6 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 1.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.3 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.3 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.5 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.3 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.2 GO:0002177 manchette(GO:0002177)
0.0 0.2 GO:0042629 mast cell granule(GO:0042629)
0.0 0.6 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.2 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.3 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.3 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.3 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.6 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.1 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.1 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.0 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.0 0.1 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0030151 molybdenum ion binding(GO:0030151)
0.3 7.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2 1.0 GO:0019770 IgG receptor activity(GO:0019770)
0.2 0.5 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.2 0.5 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.1 1.1 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 0.9 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.1 0.4 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 0.4 GO:0004568 chitinase activity(GO:0004568)
0.1 0.4 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 0.3 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 1.4 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.4 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 0.3 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 0.2 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 0.4 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.5 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.3 GO:0031720 haptoglobin binding(GO:0031720)
0.1 0.8 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 1.0 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 0.5 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 0.3 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 1.2 GO:0042287 MHC protein binding(GO:0042287)
0.1 0.2 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.1 0.2 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.1 1.2 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 0.9 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0008410 CoA-transferase activity(GO:0008410)
0.0 0.2 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.4 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 2.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.3 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.7 GO:0050811 GABA-A receptor activity(GO:0004890) GABA receptor binding(GO:0050811)
0.0 0.1 GO:0070976 TIR domain binding(GO:0070976)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.5 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.1 GO:0071568 UFM1 transferase activity(GO:0071568)
0.0 0.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.6 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.3 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 2.3 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.5 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.2 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.6 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.3 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.2 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 1.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.2 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.0 0.3 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.4 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 1.0 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.2 GO:0048038 quinone binding(GO:0048038)
0.0 0.1 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.0 0.2 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0089720 caspase binding(GO:0089720)
0.0 0.4 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.2 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0051378 primary amine oxidase activity(GO:0008131) serotonin binding(GO:0051378)
0.0 0.1 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.1 GO:1903135 cupric ion binding(GO:1903135)
0.0 0.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.4 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.0 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.2 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.2 GO:0070402 NADPH binding(GO:0070402)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.0 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 1.4 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.7 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.6 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.3 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 2.5 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.2 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 0.3 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.7 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.9 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.4 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.4 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.4 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 1.1 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.1 0.8 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.1 1.0 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.5 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.0 1.0 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.6 REACTOME_GAP_JUNCTION_TRAFFICKING Genes involved in Gap junction trafficking
0.0 0.3 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 1.2 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.6 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.3 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.2 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.1 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.1 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.6 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.4 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.4 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.2 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.2 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.1 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 2.2 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME_NEF_MEDIATES_DOWN_MODULATION_OF_CELL_SURFACE_RECEPTORS_BY_RECRUITING_THEM_TO_CLATHRIN_ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.0 0.3 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.1 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC