Motif ID: Mafa
Z-value: 1.099

Transcription factors associated with Mafa:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Mafa | ENSMUSG00000047591.4 | Mafa |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Mafa | mm10_v2_chr15_-_75747922_75747922 | 0.01 | 9.7e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.5 | 7.5 | GO:0050925 | negative regulation of negative chemotaxis(GO:0050925) |
0.8 | 4.7 | GO:0015015 | heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015) |
0.8 | 2.3 | GO:0009174 | UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049) |
0.6 | 2.5 | GO:0071596 | ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596) |
0.6 | 3.1 | GO:0034436 | glycoprotein transport(GO:0034436) |
0.6 | 7.7 | GO:1901898 | negative regulation of relaxation of cardiac muscle(GO:1901898) |
0.6 | 2.3 | GO:2001012 | mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012) |
0.5 | 8.0 | GO:0060363 | cranial suture morphogenesis(GO:0060363) |
0.4 | 1.3 | GO:0002430 | complement receptor mediated signaling pathway(GO:0002430) GPI anchor release(GO:0006507) |
0.4 | 4.1 | GO:0033631 | cell-cell adhesion mediated by integrin(GO:0033631) |
0.4 | 3.4 | GO:0035507 | regulation of myosin-light-chain-phosphatase activity(GO:0035507) |
0.3 | 6.1 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
0.3 | 2.1 | GO:0036072 | intramembranous ossification(GO:0001957) direct ossification(GO:0036072) |
0.2 | 1.9 | GO:0042769 | DNA damage response, detection of DNA damage(GO:0042769) |
0.2 | 0.8 | GO:0046709 | IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709) |
0.2 | 16.9 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
0.2 | 6.6 | GO:0003333 | amino acid transmembrane transport(GO:0003333) |
0.2 | 1.9 | GO:0046543 | development of secondary female sexual characteristics(GO:0046543) |
0.1 | 1.5 | GO:0033603 | positive regulation of dopamine secretion(GO:0033603) |
0.1 | 1.5 | GO:0006020 | inositol metabolic process(GO:0006020) |
0.1 | 1.8 | GO:0060159 | regulation of dopamine receptor signaling pathway(GO:0060159) |
0.1 | 1.1 | GO:0070072 | vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
0.1 | 5.8 | GO:0045744 | negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744) |
0.1 | 1.3 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
0.1 | 1.4 | GO:1900454 | positive regulation of long term synaptic depression(GO:1900454) |
0.1 | 2.5 | GO:0071480 | cellular response to gamma radiation(GO:0071480) |
0.1 | 0.6 | GO:0010825 | positive regulation of centrosome duplication(GO:0010825) |
0.1 | 0.3 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
0.0 | 0.2 | GO:0048133 | NK T cell differentiation(GO:0001865) germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138) germline stem cell asymmetric division(GO:0098728) |
0.0 | 3.6 | GO:0072384 | organelle transport along microtubule(GO:0072384) |
0.0 | 0.5 | GO:0021940 | positive regulation of cerebellar granule cell precursor proliferation(GO:0021940) |
0.0 | 0.3 | GO:0060046 | regulation of acrosome reaction(GO:0060046) |
0.0 | 0.2 | GO:0010700 | negative regulation of norepinephrine secretion(GO:0010700) |
0.0 | 0.5 | GO:0008272 | sulfate transport(GO:0008272) |
0.0 | 3.8 | GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) |
0.0 | 0.5 | GO:0072112 | renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311) |
0.0 | 1.1 | GO:0001919 | regulation of receptor recycling(GO:0001919) |
0.0 | 0.8 | GO:0045104 | intermediate filament cytoskeleton organization(GO:0045104) |
0.0 | 0.7 | GO:0007212 | dopamine receptor signaling pathway(GO:0007212) |
0.0 | 2.2 | GO:0048663 | neuron fate commitment(GO:0048663) |
0.0 | 0.2 | GO:0031914 | negative regulation of synaptic plasticity(GO:0031914) |
0.0 | 1.5 | GO:0051453 | regulation of intracellular pH(GO:0051453) |
0.0 | 0.1 | GO:0060821 | inactivation of X chromosome by DNA methylation(GO:0060821) |
0.0 | 0.1 | GO:0060406 | positive regulation of penile erection(GO:0060406) |
0.0 | 1.6 | GO:0034446 | substrate adhesion-dependent cell spreading(GO:0034446) |
0.0 | 1.8 | GO:0046488 | phosphatidylinositol metabolic process(GO:0046488) |
0.0 | 0.5 | GO:0035458 | cellular response to interferon-beta(GO:0035458) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.0 | 8.0 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
0.4 | 3.6 | GO:0071598 | neuronal ribonucleoprotein granule(GO:0071598) |
0.3 | 4.1 | GO:0044294 | dendritic growth cone(GO:0044294) |
0.3 | 7.7 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
0.3 | 3.1 | GO:0034361 | very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385) |
0.2 | 7.5 | GO:0030673 | axolemma(GO:0030673) |
0.2 | 1.5 | GO:0005883 | neurofilament(GO:0005883) |
0.2 | 1.1 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
0.1 | 6.1 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
0.1 | 0.8 | GO:0060053 | neurofilament cytoskeleton(GO:0060053) |
0.1 | 1.3 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
0.1 | 1.9 | GO:0000242 | pericentriolar material(GO:0000242) |
0.1 | 17.1 | GO:0045211 | postsynaptic membrane(GO:0045211) |
0.0 | 4.9 | GO:0001650 | fibrillar center(GO:0001650) |
0.0 | 0.3 | GO:0097225 | sperm midpiece(GO:0097225) |
0.0 | 0.7 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
0.0 | 0.5 | GO:0008180 | COP9 signalosome(GO:0008180) |
0.0 | 1.6 | GO:0005874 | microtubule(GO:0005874) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.2 | 4.7 | GO:0017095 | heparan sulfate 6-O-sulfotransferase activity(GO:0017095) |
1.0 | 3.1 | GO:0034437 | very-low-density lipoprotein particle binding(GO:0034189) glycoprotein transporter activity(GO:0034437) |
0.8 | 7.5 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
0.7 | 0.7 | GO:0051429 | corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
0.7 | 4.1 | GO:0033691 | sialic acid binding(GO:0033691) |
0.5 | 2.3 | GO:0004849 | uridine kinase activity(GO:0004849) |
0.4 | 2.5 | GO:0070728 | leucine binding(GO:0070728) |
0.4 | 1.5 | GO:0000832 | inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724) |
0.2 | 7.7 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
0.2 | 7.2 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
0.2 | 1.8 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
0.1 | 0.8 | GO:0098519 | nucleotide phosphatase activity, acting on free nucleotides(GO:0098519) |
0.1 | 1.3 | GO:0004630 | phospholipase D activity(GO:0004630) |
0.1 | 0.5 | GO:0043125 | ErbB-3 class receptor binding(GO:0043125) |
0.1 | 0.1 | GO:0004065 | arylsulfatase activity(GO:0004065) |
0.1 | 0.5 | GO:0008853 | exodeoxyribonuclease III activity(GO:0008853) |
0.1 | 3.8 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
0.1 | 1.5 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
0.1 | 6.6 | GO:0015171 | amino acid transmembrane transporter activity(GO:0015171) |
0.1 | 0.3 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
0.1 | 0.8 | GO:0019215 | intermediate filament binding(GO:0019215) |
0.1 | 1.9 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
0.0 | 0.8 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
0.0 | 3.6 | GO:0019894 | kinesin binding(GO:0019894) |
0.0 | 1.4 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
0.0 | 1.0 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
0.0 | 3.4 | GO:0002039 | p53 binding(GO:0002039) |
0.0 | 0.6 | GO:0016805 | dipeptidase activity(GO:0016805) |
0.0 | 2.3 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
0.0 | 1.8 | GO:0004714 | transmembrane receptor protein tyrosine kinase activity(GO:0004714) |
0.0 | 0.2 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
0.0 | 0.1 | GO:0031686 | A1 adenosine receptor binding(GO:0031686) |
0.0 | 3.3 | GO:0017137 | Rab GTPase binding(GO:0017137) |
0.0 | 9.8 | GO:0005509 | calcium ion binding(GO:0005509) |
0.0 | 1.1 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
0.0 | 2.5 | GO:0001085 | RNA polymerase II transcription factor binding(GO:0001085) |
0.0 | 0.2 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
0.0 | 2.2 | GO:0031267 | small GTPase binding(GO:0031267) |
0.0 | 5.9 | GO:0008134 | transcription factor binding(GO:0008134) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 1.9 | SA_G2_AND_M_PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
0.1 | 2.5 | PID_TCR_RAS_PATHWAY | Ras signaling in the CD4+ TCR pathway |
0.1 | 4.3 | PID_UPA_UPAR_PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
0.1 | 3.2 | PID_INTEGRIN3_PATHWAY | Beta3 integrin cell surface interactions |
0.1 | 0.7 | PID_S1P_S1P1_PATHWAY | S1P1 pathway |
0.0 | 0.4 | PID_ERBB_NETWORK_PATHWAY | ErbB receptor signaling network |
0.0 | 0.9 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 0.7 | REACTOME_G_PROTEIN_ACTIVATION | Genes involved in G-protein activation |
0.2 | 7.9 | REACTOME_DARPP_32_EVENTS | Genes involved in DARPP-32 events |
0.2 | 7.5 | REACTOME_SIGNALING_BY_ROBO_RECEPTOR | Genes involved in Signaling by Robo receptor |
0.2 | 2.4 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
0.1 | 3.6 | REACTOME_KINESINS | Genes involved in Kinesins |
0.1 | 4.1 | REACTOME_BASIGIN_INTERACTIONS | Genes involved in Basigin interactions |
0.1 | 4.7 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
0.1 | 7.2 | REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS | Genes involved in G alpha (z) signalling events |
0.1 | 2.5 | REACTOME_ERK_MAPK_TARGETS | Genes involved in ERK/MAPK targets |
0.1 | 0.5 | REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR | Genes involved in Trafficking and processing of endosomal TLR |
0.0 | 1.0 | REACTOME_INSULIN_RECEPTOR_RECYCLING | Genes involved in Insulin receptor recycling |
0.0 | 0.4 | REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
0.0 | 1.5 | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
0.0 | 0.1 | REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
0.0 | 0.9 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | Genes involved in NRAGE signals death through JNK |