Motif ID: Nr2c2

Z-value: 1.043


Transcription factors associated with Nr2c2:

Gene SymbolEntrez IDGene Name
Nr2c2 ENSMUSG00000005893.8 Nr2c2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr2c2mm10_v2_chr6_+_92091378_92091390-0.774.9e-09Click!


Activity profile for motif Nr2c2.

activity profile for motif Nr2c2


Sorted Z-values histogram for motif Nr2c2

Sorted Z-values for motif Nr2c2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr2c2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_120120138 6.760 ENSMUST00000112648.1
ENSMUST00000128408.1
Dbi

diazepam binding inhibitor

chr1_-_133424377 5.391 ENSMUST00000153799.1
Sox13
SRY-box containing gene 13
chr13_-_24761861 4.860 ENSMUST00000006898.3
ENSMUST00000110382.2
Gmnn

geminin

chr1_-_172219715 4.616 ENSMUST00000170700.1
ENSMUST00000003554.4
Casq1

calsequestrin 1

chr10_+_88147061 4.109 ENSMUST00000169309.1
Nup37
nucleoporin 37
chr6_-_95718800 4.091 ENSMUST00000079847.5
Suclg2
succinate-Coenzyme A ligase, GDP-forming, beta subunit
chr10_+_88146992 4.050 ENSMUST00000052355.7
Nup37
nucleoporin 37
chr10_+_84756055 3.997 ENSMUST00000060397.6
Rfx4
regulatory factor X, 4 (influences HLA class II expression)
chr1_+_166254095 3.958 ENSMUST00000111416.1
Ildr2
immunoglobulin-like domain containing receptor 2
chr4_-_97778042 3.809 ENSMUST00000146447.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr8_-_105707933 3.786 ENSMUST00000013299.9
Enkd1
enkurin domain containing 1
chr19_+_38395980 3.765 ENSMUST00000054098.2
Slc35g1
solute carrier family 35, member G1
chr4_-_137766474 3.515 ENSMUST00000139951.1
Alpl
alkaline phosphatase, liver/bone/kidney
chr1_-_163289214 3.488 ENSMUST00000183691.1
Prrx1
paired related homeobox 1
chr7_+_79500018 3.381 ENSMUST00000182495.1
ENSMUST00000183043.1
AI854517

expressed sequence AI854517

chr7_+_79500081 3.357 ENSMUST00000181511.2
ENSMUST00000182937.1
AI854517

expressed sequence AI854517

chr10_-_13324160 3.287 ENSMUST00000105545.4
Phactr2
phosphatase and actin regulator 2
chr8_+_88521344 3.265 ENSMUST00000034086.5
Nkd1
naked cuticle 1 homolog (Drosophila)
chr17_-_56830916 3.134 ENSMUST00000002444.7
ENSMUST00000086801.5
Rfx2

regulatory factor X, 2 (influences HLA class II expression)

chr11_-_90002881 2.978 ENSMUST00000020864.8
Pctp
phosphatidylcholine transfer protein
chr10_-_13324250 2.935 ENSMUST00000105543.1
Phactr2
phosphatase and actin regulator 2
chr10_-_88146867 2.912 ENSMUST00000164121.1
ENSMUST00000164803.1
ENSMUST00000168163.1
ENSMUST00000048518.9
Parpbp



PARP1 binding protein



chr1_-_120120937 2.882 ENSMUST00000151708.1
Dbi
diazepam binding inhibitor
chr1_+_191821444 2.823 ENSMUST00000027931.7
Nek2
NIMA (never in mitosis gene a)-related expressed kinase 2
chr1_+_12718496 2.813 ENSMUST00000088585.3
Sulf1
sulfatase 1
chr17_+_35049966 2.799 ENSMUST00000007257.9
Clic1
chloride intracellular channel 1
chr1_-_172206775 2.726 ENSMUST00000013842.5
ENSMUST00000111247.1
Pea15a

phosphoprotein enriched in astrocytes 15A

chr4_-_41697040 2.640 ENSMUST00000102962.3
ENSMUST00000084701.5
Cntfr

ciliary neurotrophic factor receptor

chr19_-_12501996 2.625 ENSMUST00000045521.7
Dtx4
deltex 4 homolog (Drosophila)
chr1_-_20820213 2.563 ENSMUST00000053266.9
Mcm3
minichromosome maintenance deficient 3 (S. cerevisiae)
chr17_+_56303321 2.476 ENSMUST00000001258.8
Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
chr3_-_89418287 2.456 ENSMUST00000029679.3
Cks1b
CDC28 protein kinase 1b
chr4_+_101419277 2.446 ENSMUST00000102780.1
ENSMUST00000106946.1
ENSMUST00000106945.1
Ak4


adenylate kinase 4


chr18_-_74207771 2.440 ENSMUST00000040188.8
ENSMUST00000177604.1
Ska1

spindle and kinetochore associated complex subunit 1

chr4_-_134767940 2.418 ENSMUST00000037828.6
Ldlrap1
low density lipoprotein receptor adaptor protein 1
chr7_-_143460989 2.384 ENSMUST00000167912.1
ENSMUST00000037287.6
Cdkn1c

cyclin-dependent kinase inhibitor 1C (P57)

chr9_+_65630552 2.374 ENSMUST00000055844.8
Rbpms2
RNA binding protein with multiple splicing 2
chr7_+_43444104 2.343 ENSMUST00000004729.3
Etfb
electron transferring flavoprotein, beta polypeptide
chr3_+_137864573 2.304 ENSMUST00000174561.1
ENSMUST00000173790.1
H2afz

H2A histone family, member Z

chr2_+_118598209 2.274 ENSMUST00000038341.7
Bub1b
budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)
chr6_+_124830217 2.271 ENSMUST00000131847.1
ENSMUST00000151674.1
Cdca3

cell division cycle associated 3

chr3_+_88081997 2.222 ENSMUST00000071812.5
Iqgap3
IQ motif containing GTPase activating protein 3
chr1_+_171329376 2.202 ENSMUST00000111299.1
ENSMUST00000064950.4
Dedd

death effector domain-containing

chr10_-_80399478 2.200 ENSMUST00000092295.3
ENSMUST00000105349.1
Mbd3

methyl-CpG binding domain protein 3

chr19_+_59260878 2.192 ENSMUST00000026084.3
Slc18a2
solute carrier family 18 (vesicular monoamine), member 2
chr4_-_139092958 2.185 ENSMUST00000042844.6
Nbl1
neuroblastoma, suppression of tumorigenicity 1
chr12_+_3954943 2.177 ENSMUST00000020990.5
Pomc
pro-opiomelanocortin-alpha
chr1_-_172206684 2.175 ENSMUST00000155109.1
Pea15a
phosphoprotein enriched in astrocytes 15A
chr3_-_104818539 2.173 ENSMUST00000106774.1
ENSMUST00000106775.1
ENSMUST00000166979.1
ENSMUST00000136148.1
Mov10



Moloney leukemia virus 10



chr17_-_25570678 2.156 ENSMUST00000025003.3
ENSMUST00000173447.1
Sox8

SRY-box containing gene 8

chr2_+_165655237 2.090 ENSMUST00000063433.7
Eya2
eyes absent 2 homolog (Drosophila)
chr10_-_80399389 2.075 ENSMUST00000105348.1
Mbd3
methyl-CpG binding domain protein 3
chr2_+_91259822 2.073 ENSMUST00000138470.1
Pacsin3
protein kinase C and casein kinase substrate in neurons 3
chr2_-_91931774 2.064 ENSMUST00000069423.6
Mdk
midkine
chr17_+_56303396 2.057 ENSMUST00000113038.1
Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
chr3_-_8923796 2.027 ENSMUST00000042148.5
Mrps28
mitochondrial ribosomal protein S28
chr6_+_29694204 2.025 ENSMUST00000046750.7
ENSMUST00000115250.3
Tspan33

tetraspanin 33

chr3_-_115888086 1.998 ENSMUST00000067500.5
A930005H10Rik
RIKEN cDNA A930005H10 gene
chr1_-_44101661 1.983 ENSMUST00000152239.1
Tex30
testis expressed 30
chr14_+_46832127 1.974 ENSMUST00000068532.8
Cgrrf1
cell growth regulator with ring finger domain 1
chr2_-_91931696 1.961 ENSMUST00000090602.5
Mdk
midkine
chr2_+_164769892 1.958 ENSMUST00000088248.6
ENSMUST00000001439.6
Ube2c

ubiquitin-conjugating enzyme E2C

chr7_-_48881596 1.955 ENSMUST00000119223.1
E2f8
E2F transcription factor 8
chr1_+_72824482 1.940 ENSMUST00000047328.4
Igfbp2
insulin-like growth factor binding protein 2
chr12_+_108792946 1.924 ENSMUST00000021692.7
Yy1
YY1 transcription factor
chr1_-_44101982 1.903 ENSMUST00000127923.1
Tex30
testis expressed 30
chrX_-_134541847 1.900 ENSMUST00000054213.4
Timm8a1
translocase of inner mitochondrial membrane 8A1
chr18_+_74779190 1.894 ENSMUST00000041053.9
Acaa2
acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase)
chr1_+_131527901 1.882 ENSMUST00000068613.4
Fam72a
family with sequence similarity 72, member A
chr11_+_117331719 1.865 ENSMUST00000100193.1
Sept9
septin 9
chr11_-_93955718 1.857 ENSMUST00000072566.4
Nme2
NME/NM23 nucleoside diphosphate kinase 2
chr14_+_57798182 1.842 ENSMUST00000111269.1
Sap18
Sin3-associated polypeptide 18
chr6_+_48841476 1.833 ENSMUST00000101426.4
Tmem176a
transmembrane protein 176A
chr5_-_110779937 1.813 ENSMUST00000112426.1
Pus1
pseudouridine synthase 1
chr12_+_3806513 1.812 ENSMUST00000172719.1
Dnmt3a
DNA methyltransferase 3A
chr14_-_52020698 1.809 ENSMUST00000067549.7
Zfp219
zinc finger protein 219
chr17_-_35132050 1.801 ENSMUST00000025249.6
Apom
apolipoprotein M
chr12_-_111672290 1.801 ENSMUST00000001304.7
Ckb
creatine kinase, brain
chr16_+_90826719 1.799 ENSMUST00000099548.2
Eva1c
eva-1 homolog C (C. elegans)
chr2_-_91931675 1.788 ENSMUST00000111309.1
Mdk
midkine
chr10_+_128790903 1.782 ENSMUST00000026411.6
Mmp19
matrix metallopeptidase 19
chr10_+_93641041 1.765 ENSMUST00000020204.4
Ntn4
netrin 4
chr11_-_4704334 1.756 ENSMUST00000058407.5
Uqcr10
ubiquinol-cytochrome c reductase, complex III subunit X
chr6_+_48841633 1.754 ENSMUST00000168406.1
Tmem176a
transmembrane protein 176A
chr19_-_50678485 1.753 ENSMUST00000111756.3
Sorcs1
VPS10 domain receptor protein SORCS 1
chr14_+_65805832 1.752 ENSMUST00000022612.3
Pbk
PDZ binding kinase
chr19_+_5474681 1.745 ENSMUST00000165485.1
ENSMUST00000166253.1
ENSMUST00000167371.1
ENSMUST00000167855.1
ENSMUST00000070118.7
Efemp2




epidermal growth factor-containing fibulin-like extracellular matrix protein 2




chr4_+_101419696 1.739 ENSMUST00000131397.1
ENSMUST00000133055.1
Ak4

adenylate kinase 4

chr12_+_111678094 1.733 ENSMUST00000084947.3
ENSMUST00000168338.1
Trmt61a

tRNA methyltransferase 61A

chr2_+_163658370 1.724 ENSMUST00000164399.1
ENSMUST00000064703.6
ENSMUST00000099105.2
ENSMUST00000152418.1
ENSMUST00000126182.1
ENSMUST00000131228.1
Pkig





protein kinase inhibitor, gamma





chr13_-_55571118 1.720 ENSMUST00000021957.6
Fam193b
family with sequence similarity 193, member B
chr4_+_63558748 1.705 ENSMUST00000077709.4
6330416G13Rik
RIKEN cDNA 6330416G13 gene
chr7_-_126800036 1.701 ENSMUST00000133514.1
ENSMUST00000151137.1
Aldoa

aldolase A, fructose-bisphosphate

chr1_-_44102362 1.689 ENSMUST00000147571.1
ENSMUST00000027215.5
ENSMUST00000147661.1
Tex30


testis expressed 30


chr7_-_126800354 1.688 ENSMUST00000106348.1
Aldoa
aldolase A, fructose-bisphosphate
chr10_+_93589413 1.669 ENSMUST00000181835.1
4933408J17Rik
RIKEN cDNA 4933408J17 gene
chr1_-_74284636 1.669 ENSMUST00000178235.1
ENSMUST00000006462.7
Aamp

angio-associated migratory protein

chr11_+_101442298 1.642 ENSMUST00000077856.6
Rpl27
ribosomal protein L27
chr5_+_111581422 1.626 ENSMUST00000064930.3
C130026L21Rik
RIKEN cDNA C130026L21 gene
chr4_+_41569775 1.612 ENSMUST00000102963.3
Dnaic1
dynein, axonemal, intermediate chain 1
chr11_+_101442440 1.610 ENSMUST00000107249.1
Rpl27
ribosomal protein L27
chr3_-_153944425 1.610 ENSMUST00000150070.1
Acadm
acyl-Coenzyme A dehydrogenase, medium chain
chr14_+_75455957 1.576 ENSMUST00000164848.1
Siah3
seven in absentia homolog 3 (Drosophila)
chr10_-_35711891 1.568 ENSMUST00000080898.2
Amd2
S-adenosylmethionine decarboxylase 2
chr14_+_65806066 1.564 ENSMUST00000139644.1
Pbk
PDZ binding kinase
chr12_+_17690793 1.555 ENSMUST00000071858.3
Hpcal1
hippocalcin-like 1
chr9_-_99876147 1.548 ENSMUST00000054819.8
Sox14
SRY-box containing gene 14
chr9_-_21073494 1.535 ENSMUST00000010348.5
Fdx1l
ferredoxin 1-like
chr11_+_80300866 1.518 ENSMUST00000017836.7
Rhbdl3
rhomboid, veinlet-like 3 (Drosophila)
chr5_-_30105359 1.515 ENSMUST00000127749.3
3110082J24Rik
RIKEN cDNA 3110082J24 gene
chr5_-_110780569 1.510 ENSMUST00000149208.1
ENSMUST00000031483.8
ENSMUST00000086643.5
ENSMUST00000170468.1
ENSMUST00000031481.6
Pus1




pseudouridine synthase 1




chr14_+_57798620 1.494 ENSMUST00000111268.1
Sap18
Sin3-associated polypeptide 18
chr17_-_34028044 1.474 ENSMUST00000045467.7
ENSMUST00000114303.3
H2-Ke6

H2-K region expressed gene 6

chr13_-_73328442 1.461 ENSMUST00000022097.5
Ndufs6
NADH dehydrogenase (ubiquinone) Fe-S protein 6
chr18_-_36744518 1.460 ENSMUST00000014438.4
Ndufa2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2
chr1_-_44102414 1.449 ENSMUST00000143327.1
ENSMUST00000133677.1
Tex30

testis expressed 30

chr17_-_31277327 1.448 ENSMUST00000024832.7
Rsph1
radial spoke head 1 homolog (Chlamydomonas)
chr6_-_85451248 1.446 ENSMUST00000113770.1
ENSMUST00000032080.2
Pradc1

protease-associated domain containing 1

chr1_-_44102433 1.431 ENSMUST00000129702.1
ENSMUST00000149502.1
ENSMUST00000156392.1
ENSMUST00000150911.1
Tex30



testis expressed 30



chr1_-_9700209 1.425 ENSMUST00000088658.4
Mybl1
myeloblastosis oncogene-like 1
chr10_-_80900749 1.413 ENSMUST00000020440.6
Timm13
translocase of inner mitochondrial membrane 13
chr11_-_101095367 1.398 ENSMUST00000019447.8
Psmc3ip
proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein
chr2_+_59160838 1.379 ENSMUST00000102754.4
ENSMUST00000168631.1
ENSMUST00000123908.1
Pkp4


plakophilin 4


chr3_-_100969644 1.353 ENSMUST00000076941.5
Ttf2
transcription termination factor, RNA polymerase II
chr3_+_94342092 1.341 ENSMUST00000029794.5
Them5
thioesterase superfamily member 5
chr11_+_51619731 1.337 ENSMUST00000127405.1
Nhp2
NHP2 ribonucleoprotein
chr19_-_3912711 1.335 ENSMUST00000075092.6
Ndufs8
NADH dehydrogenase (ubiquinone) Fe-S protein 8
chr7_+_30232032 1.333 ENSMUST00000149654.1
Polr2i
polymerase (RNA) II (DNA directed) polypeptide I
chr1_-_170306332 1.330 ENSMUST00000179801.1
Gm7694
predicted gene 7694
chr7_-_23947237 1.329 ENSMUST00000086013.2
Gm10175
predicted gene 10175
chr14_+_57798637 1.319 ENSMUST00000111267.1
Sap18
Sin3-associated polypeptide 18
chr10_+_88201117 1.318 ENSMUST00000182183.1
Ccdc53
coiled-coil domain containing 53
chr4_+_130055010 1.313 ENSMUST00000123617.1
Col16a1
collagen, type XVI, alpha 1
chr1_+_55088132 1.305 ENSMUST00000075242.6
Hspe1
heat shock protein 1 (chaperonin 10)
chr7_-_44548733 1.302 ENSMUST00000145956.1
ENSMUST00000049343.8
Pold1

polymerase (DNA directed), delta 1, catalytic subunit

chr5_+_136116631 1.300 ENSMUST00000111127.1
ENSMUST00000041366.7
ENSMUST00000111129.1
Polr2j


polymerase (RNA) II (DNA directed) polypeptide J


chr15_-_81871883 1.282 ENSMUST00000023117.8
Phf5a
PHD finger protein 5A
chr2_-_93452679 1.266 ENSMUST00000111257.1
ENSMUST00000145553.1
Cd82

CD82 antigen

chr5_-_108434373 1.266 ENSMUST00000049628.9
ENSMUST00000118632.1
Atp5k

ATP synthase, H+ transporting, mitochondrial F1F0 complex, subunit e

chr16_-_18248697 1.261 ENSMUST00000115645.3
Ranbp1
RAN binding protein 1
chr6_+_82052307 1.257 ENSMUST00000149023.1
Eva1a
eva-1 homolog A (C. elegans)
chr2_+_174415804 1.248 ENSMUST00000109075.1
ENSMUST00000016397.6
Nelfcd

negative elongation factor complex member C/D, Th1l

chr8_-_116993459 1.239 ENSMUST00000040484.5
Gcsh
glycine cleavage system protein H (aminomethyl carrier)
chr7_+_30232310 1.233 ENSMUST00000108193.1
ENSMUST00000108192.1
Polr2i

polymerase (RNA) II (DNA directed) polypeptide I

chr6_+_71282280 1.227 ENSMUST00000080949.7
Krcc1
lysine-rich coiled-coil 1
chr6_+_124712279 1.217 ENSMUST00000004375.9
Phb2
prohibitin 2
chr4_+_41760454 1.205 ENSMUST00000108040.1
Il11ra1
interleukin 11 receptor, alpha chain 1
chr11_-_100850724 1.200 ENSMUST00000004143.2
Stat5b
signal transducer and activator of transcription 5B
chr2_-_84743655 1.196 ENSMUST00000181711.1
Gm19426
predicted gene, 19426
chr1_+_59482133 1.174 ENSMUST00000114246.2
ENSMUST00000037105.6
Fzd7

frizzled homolog 7 (Drosophila)

chr1_+_171329569 1.167 ENSMUST00000142063.1
ENSMUST00000129116.1
Dedd

death effector domain-containing

chr17_-_35667546 1.165 ENSMUST00000043674.8
Vars2
valyl-tRNA synthetase 2, mitochondrial (putative)
chr8_+_95825353 1.148 ENSMUST00000074053.4
Gm10094
predicted gene 10094
chr2_+_154656959 1.144 ENSMUST00000044277.9
Chmp4b
charged multivesicular body protein 4B
chr10_-_93589621 1.132 ENSMUST00000020203.6
Snrpf
small nuclear ribonucleoprotein polypeptide F
chr5_+_129725063 1.124 ENSMUST00000086046.3
Gbas
glioblastoma amplified sequence
chr9_+_21002737 1.119 ENSMUST00000003386.5
Mrpl4
mitochondrial ribosomal protein L4
chr10_+_88201158 1.118 ENSMUST00000171151.2
Ccdc53
coiled-coil domain containing 53
chr8_-_123318553 1.107 ENSMUST00000118395.1
ENSMUST00000035495.8
Fanca

Fanconi anemia, complementation group A

chr9_-_124424154 1.107 ENSMUST00000180270.1
Ppp2r3d
protein phosphatase 2 (formerly 2A), regulatory subunit B'', delta
chr19_-_43912392 1.105 ENSMUST00000026209.4
Dnmbp
dynamin binding protein
chr10_+_128747850 1.102 ENSMUST00000163377.2
Wibg
within bgcn homolog (Drosophila)
chr19_+_45015168 1.100 ENSMUST00000039016.6
Lzts2
leucine zipper, putative tumor suppressor 2
chr4_+_62619515 1.098 ENSMUST00000084521.4
ENSMUST00000107424.1
Rgs3

regulator of G-protein signaling 3

chr4_+_118409331 1.094 ENSMUST00000084319.4
ENSMUST00000106384.3
ENSMUST00000126089.1
ENSMUST00000073881.1
ENSMUST00000019229.8
ENSMUST00000144577.1
Med8





mediator of RNA polymerase II transcription, subunit 8 homolog (yeast)





chr1_-_183221529 1.093 ENSMUST00000003035.5
Disp1
dispatched homolog 1 (Drosophila)
chr8_-_91801547 1.074 ENSMUST00000093312.4
Irx3
Iroquois related homeobox 3 (Drosophila)
chr19_+_46707443 1.066 ENSMUST00000003655.7
As3mt
arsenic (+3 oxidation state) methyltransferase
chr7_+_3617357 1.060 ENSMUST00000076657.4
ENSMUST00000108644.1
Ndufa3

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3

chr4_-_103215147 1.059 ENSMUST00000150285.1
Slc35d1
solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1
chr17_+_57249450 1.046 ENSMUST00000019631.9
Trip10
thyroid hormone receptor interactor 10
chr11_+_109485606 1.044 ENSMUST00000106697.1
Arsg
arylsulfatase G
chr5_-_117389029 1.040 ENSMUST00000111953.1
ENSMUST00000086461.6
Rfc5

replication factor C (activator 1) 5

chr11_-_78751656 1.040 ENSMUST00000059468.4
Fam58b
family with sequence similarity 58, member B
chr15_+_79028212 1.040 ENSMUST00000180086.1
H1f0
H1 histone family, member 0
chr5_-_138994935 1.019 ENSMUST00000046901.7
ENSMUST00000076095.7
Pdgfa

platelet derived growth factor, alpha

chr17_+_34850373 1.018 ENSMUST00000097343.4
ENSMUST00000173357.1
ENSMUST00000173065.1
ENSMUST00000165953.2
Nelfe



negative elongation factor complex member E, Rdbp



chr1_+_74284930 1.018 ENSMUST00000113805.1
ENSMUST00000027370.6
ENSMUST00000087226.4
Pnkd


paroxysmal nonkinesiogenic dyskinesia


chr19_-_60874526 1.014 ENSMUST00000025961.6
Prdx3
peroxiredoxin 3
chr6_-_48841373 1.012 ENSMUST00000166247.1
Tmem176b
transmembrane protein 176B
chr2_-_90904827 0.998 ENSMUST00000005647.3
Ndufs3
NADH dehydrogenase (ubiquinone) Fe-S protein 3
chr6_+_86365673 0.992 ENSMUST00000071492.7
Fam136a
family with sequence similarity 136, member A
chr7_-_89941196 0.984 ENSMUST00000117354.1
l7Rn6
lethal, Chr 7, Rinchik 6
chr8_-_4275886 0.983 ENSMUST00000003029.7
Timm44
translocase of inner mitochondrial membrane 44
chr2_+_19199266 0.975 ENSMUST00000114640.2
ENSMUST00000049255.6
Armc3

armadillo repeat containing 3

chr17_-_87265866 0.970 ENSMUST00000145895.1
ENSMUST00000129616.1
ENSMUST00000155904.1
ENSMUST00000151155.1
ENSMUST00000144236.1
ENSMUST00000024963.3
Mcfd2





multiple coagulation factor deficiency 2





chr1_+_136467958 0.970 ENSMUST00000047817.6
Kif14
kinesin family member 14
chr17_+_56717759 0.970 ENSMUST00000002452.6
Ndufa11
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 11
chr5_-_137307633 0.964 ENSMUST00000040873.7
Srrt
serrate RNA effector molecule homolog (Arabidopsis)
chr9_-_108649349 0.962 ENSMUST00000013338.8
Arih2
ariadne homolog 2 (Drosophila)
chr5_+_36484578 0.959 ENSMUST00000060100.1
Ccdc96
coiled-coil domain containing 96
chr8_-_47675556 0.959 ENSMUST00000125536.1
Ing2
inhibitor of growth family, member 2
chr3_-_89998656 0.956 ENSMUST00000079724.4
Hax1
HCLS1 associated X-1
chr14_+_122534305 0.944 ENSMUST00000154206.1
ENSMUST00000038374.6
ENSMUST00000135578.1
Pcca


propionyl-Coenzyme A carboxylase, alpha polypeptide


chr8_+_83566671 0.941 ENSMUST00000036996.5
Ndufb7
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7
chr11_+_97663366 0.936 ENSMUST00000044730.5
Mllt6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr15_+_82016369 0.936 ENSMUST00000069530.6
Xrcc6
X-ray repair complementing defective repair in Chinese hamster cells 6
chr4_-_137048695 0.933 ENSMUST00000049583.7
Zbtb40
zinc finger and BTB domain containing 40
chr7_+_27258725 0.929 ENSMUST00000079258.6
Numbl
numb-like
chr7_+_44465391 0.916 ENSMUST00000035929.4
ENSMUST00000146128.1
Aspdh

aspartate dehydrogenase domain containing


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.8 GO:0030421 defecation(GO:0030421)
1.9 9.6 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
1.5 4.6 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.9 2.6 GO:0001193 maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193)
0.8 4.1 GO:0072289 metanephric nephron tubule formation(GO:0072289)
0.8 2.4 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.8 4.0 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.8 2.3 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.8 3.8 GO:1990034 calcium ion export from cell(GO:1990034)
0.7 2.2 GO:0035934 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.7 2.1 GO:0046032 ADP catabolic process(GO:0046032)
0.7 2.8 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.7 2.8 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.7 2.6 GO:0003360 brainstem development(GO:0003360)
0.7 4.6 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.7 2.0 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.6 1.9 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.6 3.5 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.6 1.7 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.6 4.4 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.6 3.3 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.5 2.2 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.5 1.6 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
0.5 1.6 GO:0006597 spermine biosynthetic process(GO:0006597)
0.5 6.6 GO:0046643 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.5 1.9 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.5 2.3 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.5 4.1 GO:0006105 succinyl-CoA metabolic process(GO:0006104) succinate metabolic process(GO:0006105)
0.5 1.8 GO:0050748 negative regulation of lipoprotein metabolic process(GO:0050748)
0.4 1.3 GO:0045004 DNA replication proofreading(GO:0045004)
0.4 2.1 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.4 6.3 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.4 1.2 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.4 1.6 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.4 2.2 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.4 1.8 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.4 1.4 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.3 1.0 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.3 3.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.3 1.3 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.3 0.7 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.3 1.3 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.3 1.0 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.3 0.9 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.3 1.8 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.3 2.4 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.3 2.4 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.3 1.2 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.3 4.3 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.3 1.4 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.3 1.7 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.3 3.5 GO:0048664 neuron fate determination(GO:0048664)
0.3 2.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.2 1.0 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.2 0.9 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.2 1.1 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.2 0.7 GO:0006553 lysine metabolic process(GO:0006553)
0.2 2.5 GO:0036158 outer dynein arm assembly(GO:0036158)
0.2 4.9 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.2 2.2 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.2 0.2 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.2 0.4 GO:0072053 renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.2 3.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.2 1.5 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.2 1.9 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.2 1.0 GO:0042538 hyperosmotic salinity response(GO:0042538)
0.2 1.9 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.2 1.4 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.2 1.0 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.2 0.2 GO:0030222 eosinophil differentiation(GO:0030222)
0.2 0.6 GO:0045014 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594)
0.2 1.8 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.2 0.6 GO:0019530 taurine metabolic process(GO:0019530)
0.2 7.2 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.2 0.7 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.2 0.5 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.2 0.8 GO:0070327 thyroid hormone transport(GO:0070327)
0.2 1.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2 1.1 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.2 0.6 GO:0044026 DNA hypermethylation(GO:0044026) hypermethylation of CpG island(GO:0044027)
0.1 1.7 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 1.8 GO:0001675 acrosome assembly(GO:0001675)
0.1 0.3 GO:0061344 arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) regulation of cell adhesion involved in heart morphogenesis(GO:0061344) blood vessel endothelial cell fate specification(GO:0097101) positive regulation of ephrin receptor signaling pathway(GO:1901189)
0.1 0.7 GO:0060161 positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.1 1.6 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.1 1.0 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 1.3 GO:0032048 cardiolipin metabolic process(GO:0032048)
0.1 1.0 GO:0031053 primary miRNA processing(GO:0031053)
0.1 1.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 2.2 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 1.0 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 1.0 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 0.2 GO:0010667 negative regulation of striated muscle cell apoptotic process(GO:0010664) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1 0.5 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 1.0 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.1 1.8 GO:0030574 collagen catabolic process(GO:0030574)
0.1 0.2 GO:0032847 regulation of cellular pH reduction(GO:0032847)
0.1 0.3 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1 2.3 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.1 0.3 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.1 0.2 GO:0002842 positive regulation of T cell mediated immune response to tumor cell(GO:0002842)
0.1 1.0 GO:0046697 decidualization(GO:0046697)
0.1 0.4 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.1 1.0 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 1.0 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.1 0.6 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 0.4 GO:0006014 D-ribose metabolic process(GO:0006014)
0.1 1.1 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 1.1 GO:0060539 diaphragm development(GO:0060539)
0.1 0.6 GO:0050942 positive regulation of pigment cell differentiation(GO:0050942)
0.1 0.9 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.8 GO:0015074 DNA integration(GO:0015074)
0.1 1.4 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.1 0.3 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.1 0.3 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.1 3.7 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.1 0.5 GO:1904923 regulation of mitophagy in response to mitochondrial depolarization(GO:1904923)
0.1 1.1 GO:0009404 toxin metabolic process(GO:0009404)
0.1 0.4 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.1 1.3 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1 3.4 GO:0046677 response to antibiotic(GO:0046677)
0.1 2.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.2 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.1 1.3 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.1 2.5 GO:0006379 mRNA cleavage(GO:0006379)
0.1 0.9 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 0.3 GO:0070459 prolactin secretion(GO:0070459)
0.1 0.8 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.1 0.3 GO:0002036 regulation of L-glutamate transport(GO:0002036) endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.5 GO:0043383 negative T cell selection(GO:0043383) negative thymic T cell selection(GO:0045060)
0.1 0.7 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.1 0.1 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.1 4.8 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.1 0.8 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.1 1.1 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 1.6 GO:0046033 AMP metabolic process(GO:0046033)
0.1 0.7 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.1 0.5 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.1 1.0 GO:0042407 cristae formation(GO:0042407)
0.1 1.9 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 3.5 GO:0070303 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.1 2.8 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 2.5 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.1 0.5 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 2.6 GO:0006270 DNA replication initiation(GO:0006270)
0.1 0.3 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.1 0.3 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
0.1 0.4 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.1 0.3 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.6 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.1 0.5 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.2 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 1.3 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.1 1.5 GO:0009649 entrainment of circadian clock(GO:0009649)
0.1 0.9 GO:0071803 actin filament network formation(GO:0051639) positive regulation of podosome assembly(GO:0071803)
0.1 0.2 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.1 0.3 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 2.8 GO:0015914 phospholipid transport(GO:0015914)
0.1 1.8 GO:0030488 tRNA methylation(GO:0030488)
0.1 0.9 GO:0030224 monocyte differentiation(GO:0030224)
0.1 0.2 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 0.2 GO:2000318 positive regulation of T-helper 17 type immune response(GO:2000318)
0.1 0.3 GO:0045059 positive thymic T cell selection(GO:0045059)
0.1 0.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.5 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 0.2 GO:1903772 regulation of viral budding via host ESCRT complex(GO:1903772)
0.0 0.5 GO:0050685 positive regulation of mRNA splicing, via spliceosome(GO:0048026) positive regulation of mRNA processing(GO:0050685)
0.0 0.8 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.5 GO:0090344 negative regulation of cell aging(GO:0090344)
0.0 6.0 GO:0051028 mRNA transport(GO:0051028)
0.0 0.7 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.6 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 1.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.5 GO:0043649 dicarboxylic acid catabolic process(GO:0043649)
0.0 1.5 GO:0031648 protein destabilization(GO:0031648)
0.0 1.0 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.7 GO:0045019 negative regulation of nitric oxide biosynthetic process(GO:0045019) negative regulation of nitric oxide metabolic process(GO:1904406)
0.0 0.2 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0 1.4 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 2.4 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108) regulation of NADP metabolic process(GO:1902031)
0.0 0.0 GO:0007521 muscle cell fate determination(GO:0007521)
0.0 2.7 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.9 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0051030 snRNA transport(GO:0051030)
0.0 0.3 GO:1903961 positive regulation of anion transmembrane transport(GO:1903961)
0.0 0.3 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.3 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.0 1.2 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.0 0.6 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 1.3 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.9 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 1.1 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.1 GO:0002489 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476) antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585)
0.0 4.3 GO:0042254 ribosome biogenesis(GO:0042254)
0.0 0.1 GO:1990839 response to endothelin(GO:1990839)
0.0 0.7 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.3 GO:1990173 regulation of establishment of protein localization to telomere(GO:0070203) protein localization to nuclear body(GO:1903405) regulation of protein localization to chromosome, telomeric region(GO:1904814) positive regulation of protein localization to chromosome, telomeric region(GO:1904816) positive regulation of establishment of protein localization to telomere(GO:1904851) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.0 0.8 GO:0043388 positive regulation of DNA binding(GO:0043388)
0.0 0.7 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:0051346 negative regulation of hydrolase activity(GO:0051346)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 1.4 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 1.6 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.8 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.1 GO:0045616 regulation of keratinocyte differentiation(GO:0045616)
0.0 0.2 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.5 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.0 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.3 GO:0006337 nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986)
0.0 0.3 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.3 GO:0001553 luteinization(GO:0001553)
0.0 1.1 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway(GO:2001243)
0.0 0.2 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.3 GO:1903020 positive regulation of glycoprotein metabolic process(GO:1903020)
0.0 0.6 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.5 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.4 GO:0097006 regulation of plasma lipoprotein particle levels(GO:0097006)
0.0 0.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 1.6 GO:0007219 Notch signaling pathway(GO:0007219)
0.0 0.0 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.2 GO:2000637 positive regulation of gene silencing by miRNA(GO:2000637)
0.0 2.4 GO:0051604 protein maturation(GO:0051604)
0.0 1.3 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 1.6 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 0.9 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.0 0.5 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.4 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.3 GO:0045454 cell redox homeostasis(GO:0045454)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.6 GO:0014802 terminal cisterna(GO:0014802)
0.9 2.6 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.7 8.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.7 4.3 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.6 2.4 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.6 5.3 GO:0061574 ASAP complex(GO:0061574)
0.6 2.3 GO:0032021 NELF complex(GO:0032021)
0.5 2.2 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.5 1.5 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.5 1.8 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.4 1.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.4 4.7 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.4 1.4 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.3 1.7 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.3 9.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.3 1.3 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.3 2.3 GO:0001740 Barr body(GO:0001740)
0.3 2.0 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.3 1.4 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.2 3.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.2 1.1 GO:0034715 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
0.2 4.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 3.5 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.2 1.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 1.4 GO:0005687 U4 snRNP(GO:0005687)
0.2 3.9 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.2 1.0 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.2 9.0 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 1.4 GO:0001520 outer dense fiber(GO:0001520)
0.2 4.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2 1.8 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.2 1.0 GO:0005663 DNA replication factor C complex(GO:0005663)
0.2 2.6 GO:0042555 MCM complex(GO:0042555)
0.2 0.7 GO:0060187 cell pole(GO:0060187)
0.2 1.0 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 7.4 GO:0000791 euchromatin(GO:0000791)
0.1 1.9 GO:0031011 Ino80 complex(GO:0031011)
0.1 0.5 GO:0008623 CHRAC(GO:0008623)
0.1 1.9 GO:0031105 septin complex(GO:0031105)
0.1 1.1 GO:0000815 ESCRT III complex(GO:0000815)
0.1 1.0 GO:0061617 MICOS complex(GO:0061617)
0.1 0.4 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 3.6 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 1.3 GO:0005686 U2 snRNP(GO:0005686)
0.1 1.4 GO:0030057 desmosome(GO:0030057)
0.1 0.8 GO:0070652 HAUS complex(GO:0070652)
0.1 0.3 GO:0055087 Ski complex(GO:0055087)
0.1 0.9 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 1.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 0.7 GO:0005638 lamin filament(GO:0005638)
0.1 1.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 17.7 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 4.1 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 0.3 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 2.0 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 1.3 GO:1904115 axon cytoplasm(GO:1904115)
0.1 3.1 GO:0034707 chloride channel complex(GO:0034707)
0.1 0.4 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 3.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 4.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 1.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.4 GO:0031415 NatA complex(GO:0031415)
0.1 0.8 GO:0031045 dense core granule(GO:0031045)
0.1 0.5 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 0.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.9 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.3 GO:0070847 core mediator complex(GO:0070847)
0.0 0.4 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.6 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 2.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.3 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 2.8 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 5.3 GO:0005875 microtubule associated complex(GO:0005875)
0.0 0.5 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.9 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.7 GO:0002080 acrosomal membrane(GO:0002080)
0.0 1.2 GO:1990204 oxidoreductase complex(GO:1990204)
0.0 0.2 GO:0005811 lipid particle(GO:0005811)
0.0 12.9 GO:0005667 transcription factor complex(GO:0005667)
0.0 2.3 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 1.2 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.8 GO:0016592 mediator complex(GO:0016592)
0.0 0.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.3 GO:0005832 zona pellucida receptor complex(GO:0002199) chaperonin-containing T-complex(GO:0005832)
0.0 0.3 GO:0045095 keratin filament(GO:0045095)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.5 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 2.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.4 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.6 GO:0001772 immunological synapse(GO:0001772)
0.0 1.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.3 GO:0010369 chromocenter(GO:0010369)
0.0 0.5 GO:0060077 inhibitory synapse(GO:0060077)
0.0 1.3 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 1.2 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.3 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.3 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 1.4 GO:0030496 midbody(GO:0030496)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 1.0 GO:0005840 ribosome(GO:0005840)
0.0 0.4 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.9 GO:0005802 trans-Golgi network(GO:0005802)
0.0 2.4 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.3 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 2.3 GO:0030141 secretory granule(GO:0030141)
0.0 1.6 GO:0005681 spliceosomal complex(GO:0005681)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 9.6 GO:0030156 benzodiazepine receptor binding(GO:0030156)
1.4 4.2 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
1.4 4.1 GO:0004774 succinate-CoA ligase activity(GO:0004774)
1.1 4.5 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.9 3.5 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.7 2.2 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.7 2.2 GO:0016015 morphogen activity(GO:0016015)
0.6 2.5 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.6 1.2 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.6 1.7 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.6 3.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.6 2.8 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.5 1.8 GO:0004111 creatine kinase activity(GO:0004111)
0.4 2.2 GO:0032027 myosin light chain binding(GO:0032027)
0.4 1.6 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.4 1.6 GO:0019808 polyamine binding(GO:0019808)
0.3 2.1 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.3 1.0 GO:0019966 interleukin-1 binding(GO:0019966)
0.3 0.9 GO:0004658 propionyl-CoA carboxylase activity(GO:0004658)
0.3 1.5 GO:0070404 NADH binding(GO:0070404)
0.3 1.2 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.3 1.4 GO:0030621 U4 snRNA binding(GO:0030621)
0.3 3.0 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.3 2.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.3 1.3 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.3 1.9 GO:0004673 protein histidine kinase activity(GO:0004673)
0.2 1.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.2 1.9 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.2 1.8 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.2 3.8 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.2 0.2 GO:0031893 vasopressin receptor binding(GO:0031893)
0.2 1.8 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.2 4.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 1.0 GO:0003680 AT DNA binding(GO:0003680)
0.2 0.8 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.2 1.8 GO:0043237 laminin-1 binding(GO:0043237)
0.2 5.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2 2.4 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.2 1.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.2 1.9 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.2 0.7 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.2 2.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 2.1 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.2 1.1 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.2 0.6 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 0.6 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.1 1.4 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 1.6 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 1.2 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.1 1.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 0.9 GO:0015288 porin activity(GO:0015288)
0.1 1.3 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 0.4 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 1.0 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 1.8 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 1.0 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 0.8 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 3.5 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.4 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.1 0.5 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.6 GO:0051525 NFAT protein binding(GO:0051525)
0.1 1.0 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 1.1 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.9 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.8 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 1.6 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 1.0 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 1.9 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 1.4 GO:0050692 DBD domain binding(GO:0050692)
0.1 1.2 GO:0015197 peptide transporter activity(GO:0015197)
0.1 7.2 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 0.5 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 0.7 GO:0034711 inhibin binding(GO:0034711)
0.1 0.7 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 2.6 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.1 0.3 GO:1990254 keratin filament binding(GO:1990254)
0.1 1.0 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 9.2 GO:0008201 heparin binding(GO:0008201)
0.1 0.4 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 0.3 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 4.3 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 0.6 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.2 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 1.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 4.4 GO:0005080 protein kinase C binding(GO:0005080)
0.1 1.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 10.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 1.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 0.5 GO:0008301 DNA binding, bending(GO:0008301)
0.1 1.8 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.1 0.8 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 0.9 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0 2.3 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.9 GO:0050811 GABA receptor binding(GO:0050811)
0.0 1.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.4 GO:0042301 phosphate ion binding(GO:0042301)
0.0 3.1 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.2 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.0 0.2 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.8 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 0.2 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.4 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.1 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.2 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 1.0 GO:0070888 E-box binding(GO:0070888)
0.0 0.6 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.3 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.2 GO:0016936 galactoside binding(GO:0016936)
0.0 0.4 GO:0001968 fibronectin binding(GO:0001968)
0.0 1.1 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 2.3 GO:0051087 chaperone binding(GO:0051087)
0.0 0.1 GO:0042731 PH domain binding(GO:0042731)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.3 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.3 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 1.7 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.7 GO:0016409 palmitoyltransferase activity(GO:0016409)
0.0 3.7 GO:0004386 helicase activity(GO:0004386)
0.0 1.0 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.2 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.8 GO:0001047 core promoter binding(GO:0001047)
0.0 0.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.5 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.2 GO:0070403 NAD+ binding(GO:0070403)
0.0 1.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.5 GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076)
0.0 1.1 GO:0002039 p53 binding(GO:0002039)
0.0 0.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.1 GO:0005178 integrin binding(GO:0005178)
0.0 1.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.7 GO:0005179 hormone activity(GO:0005179)
0.0 0.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.3 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.6 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.8 GO:0019838 growth factor binding(GO:0019838)
0.0 0.2 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.9 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.3 GO:0017091 AU-rich element binding(GO:0017091)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.1 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.1 6.2 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.1 12.3 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.1 2.2 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.1 3.8 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 3.5 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.1 1.4 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.1 1.2 PID_IL5_PATHWAY IL5-mediated signaling events
0.1 1.0 PID_IL3_PATHWAY IL3-mediated signaling events
0.1 4.1 PID_E2F_PATHWAY E2F transcription factor network
0.1 1.2 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.1 0.7 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.1 1.8 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.1 3.5 PID_P73PATHWAY p73 transcription factor network
0.0 2.1 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 4.4 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.3 NABA_COLLAGENS Genes encoding collagen proteins
0.0 2.5 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 1.1 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 2.4 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 2.3 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.9 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.0 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 1.9 PID_PLK1_PATHWAY PLK1 signaling events
0.0 0.7 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 0.5 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 0.4 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 0.7 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 0.8 SIG_CHEMOTAXIS Genes related to chemotaxis
0.0 0.9 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.0 0.4 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 0.4 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 0.2 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.0 1.8 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.7 PID_CMYB_PATHWAY C-MYB transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 REACTOME_ANDROGEN_BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.3 7.1 REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.3 5.1 REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.3 8.2 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.2 3.9 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.2 2.2 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.2 3.3 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.2 2.3 REACTOME_POL_SWITCHING Genes involved in Polymerase switching
0.2 2.4 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 2.6 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.2 11.1 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.2 0.6 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.2 2.6 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 1.1 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 1.0 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 1.9 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.1 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.1 1.2 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.1 1.1 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 4.5 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.1 2.5 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 2.7 REACTOME_G1_PHASE Genes involved in G1 Phase
0.1 3.8 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.1 0.8 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.4 REACTOME_INTEGRATION_OF_PROVIRUS Genes involved in Integration of provirus
0.1 1.3 REACTOME_EXTENSION_OF_TELOMERES Genes involved in Extension of Telomeres
0.1 0.5 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1 2.6 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 1.9 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.9 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.1 1.0 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 2.3 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.1 0.4 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.1 1.2 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 1.1 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.1 0.9 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.1 0.5 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 5.3 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 0.4 REACTOME_ACYL_CHAIN_REMODELLING_OF_PS Genes involved in Acyl chain remodelling of PS
0.0 2.7 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.0 0.9 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.7 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.0 0.6 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.5 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.7 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.3 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 2.4 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.0 0.5 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.6 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.9 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.2 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.6 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.4 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.5 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 1.1 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.1 REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.2 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.0 1.2 REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS Genes involved in Host Interactions of HIV factors