Motif ID: Tcf21_Msc

Z-value: 1.166

Transcription factors associated with Tcf21_Msc:

Gene SymbolEntrez IDGene Name
Msc ENSMUSG00000025930.5 Msc
Tcf21 ENSMUSG00000045680.7 Tcf21






Network of associatons between targets according to the STRING database.



First level regulatory network of Tcf21_Msc

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_144893077 7.543 ENSMUST00000154208.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr8_-_122432924 6.133 ENSMUST00000017604.8
Cyba
cytochrome b-245, alpha polypeptide
chr8_+_94172618 5.090 ENSMUST00000034214.6
Mt2
metallothionein 2
chr4_+_144892813 5.006 ENSMUST00000105744.1
ENSMUST00000171001.1
Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr7_+_122289297 4.961 ENSMUST00000064989.5
ENSMUST00000064921.4
Prkcb

protein kinase C, beta

chr16_+_91269759 4.811 ENSMUST00000056882.5
Olig1
oligodendrocyte transcription factor 1
chr15_+_78926720 4.446 ENSMUST00000089377.5
Lgals1
lectin, galactose binding, soluble 1
chr3_+_90537242 4.441 ENSMUST00000098911.3
S100a16
S100 calcium binding protein A16
chr12_+_108334341 4.300 ENSMUST00000021684.4
Cyp46a1
cytochrome P450, family 46, subfamily a, polypeptide 1
chr9_-_40346290 4.250 ENSMUST00000121357.1
Gramd1b
GRAM domain containing 1B
chr5_-_28210022 4.185 ENSMUST00000118882.1
Cnpy1
canopy 1 homolog (zebrafish)
chr4_+_48045144 4.100 ENSMUST00000030025.3
Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr2_-_122611238 4.008 ENSMUST00000028624.8
Gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr3_+_90537306 3.876 ENSMUST00000107335.1
S100a16
S100 calcium binding protein A16
chr1_-_14310198 3.795 ENSMUST00000168081.2
ENSMUST00000027066.6
Eya1

eyes absent 1 homolog (Drosophila)

chr11_+_99864476 3.712 ENSMUST00000092694.3
Gm11559
predicted gene 11559
chr4_+_144893127 3.590 ENSMUST00000142808.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr11_-_55419898 3.316 ENSMUST00000108858.1
ENSMUST00000141530.1
Sparc

secreted acidic cysteine rich glycoprotein

chr18_+_60293372 3.281 ENSMUST00000171297.1
F830016B08Rik
RIKEN cDNA F830016B08 gene
chr16_+_43510267 3.190 ENSMUST00000114695.2
Zbtb20
zinc finger and BTB domain containing 20
chr5_-_135251209 3.179 ENSMUST00000062572.2
Fzd9
frizzled homolog 9 (Drosophila)
chrX_+_100730178 3.064 ENSMUST00000113744.1
Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr6_-_54566484 2.675 ENSMUST00000019268.4
Scrn1
secernin 1
chr12_-_119238794 2.582 ENSMUST00000026360.8
Itgb8
integrin beta 8
chr6_+_29398920 2.504 ENSMUST00000181464.1
ENSMUST00000180829.1
Ccdc136

coiled-coil domain containing 136

chr3_+_14863495 2.491 ENSMUST00000029076.4
Car3
carbonic anhydrase 3
chr3_-_84305385 2.460 ENSMUST00000122849.1
ENSMUST00000132283.1
Trim2

tripartite motif-containing 2

chr10_-_18743691 2.412 ENSMUST00000019999.5
D10Bwg1379e
DNA segment, Chr 10, Brigham & Women's Genetics 1379 expressed
chr10_-_27616895 2.407 ENSMUST00000092639.5
Lama2
laminin, alpha 2
chr11_-_109611417 2.399 ENSMUST00000103060.3
ENSMUST00000047186.3
ENSMUST00000106689.1
Wipi1


WD repeat domain, phosphoinositide interacting 1


chr2_-_105399286 2.330 ENSMUST00000006128.6
Rcn1
reticulocalbin 1
chr2_-_162661075 2.263 ENSMUST00000109442.1
ENSMUST00000109445.2
ENSMUST00000109443.1
ENSMUST00000109441.1
Ptprt



protein tyrosine phosphatase, receptor type, T



chr3_+_89436699 2.235 ENSMUST00000038942.3
ENSMUST00000130858.1
Pbxip1

pre B cell leukemia transcription factor interacting protein 1

chrX_+_169036610 2.229 ENSMUST00000087016.4
ENSMUST00000112129.1
ENSMUST00000112131.2
Arhgap6


Rho GTPase activating protein 6


chr5_-_28210168 2.185 ENSMUST00000117098.1
Cnpy1
canopy 1 homolog (zebrafish)
chr15_+_89429560 2.122 ENSMUST00000168646.1
C730034F03Rik
RIKEN cDNA C730034F03 gene
chr1_-_162866502 2.107 ENSMUST00000046049.7
Fmo1
flavin containing monooxygenase 1
chr11_-_107915041 2.103 ENSMUST00000039071.2
Cacng5
calcium channel, voltage-dependent, gamma subunit 5
chr2_-_170131156 2.064 ENSMUST00000063710.6
Zfp217
zinc finger protein 217
chr4_-_87806276 1.998 ENSMUST00000148059.1
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr7_-_80688852 1.928 ENSMUST00000122255.1
Crtc3
CREB regulated transcription coactivator 3
chrX_+_36328353 1.926 ENSMUST00000016383.3
Lonrf3
LON peptidase N-terminal domain and ring finger 3
chr4_-_87806296 1.920 ENSMUST00000126353.1
ENSMUST00000149357.1
Mllt3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr6_+_112273758 1.894 ENSMUST00000032376.5
Lmcd1
LIM and cysteine-rich domains 1
chr3_-_68870266 1.888 ENSMUST00000166328.1
Gm17641
predicted gene, 17641
chr3_+_86084434 1.867 ENSMUST00000107664.2
Sh3d19
SH3 domain protein D19
chr15_+_25622525 1.864 ENSMUST00000110457.1
ENSMUST00000137601.1
Myo10

myosin X

chr11_+_53770458 1.844 ENSMUST00000138913.1
ENSMUST00000123376.1
ENSMUST00000019043.6
ENSMUST00000133291.1
Irf1



interferon regulatory factor 1



chr7_+_19094594 1.825 ENSMUST00000049454.5
Six5
sine oculis-related homeobox 5
chr11_+_112782182 1.787 ENSMUST00000000579.2
Sox9
SRY-box containing gene 9
chr6_+_29694204 1.777 ENSMUST00000046750.7
ENSMUST00000115250.3
Tspan33

tetraspanin 33

chr13_-_113046357 1.728 ENSMUST00000022282.3
Gpx8
glutathione peroxidase 8 (putative)
chr5_+_103754560 1.712 ENSMUST00000153165.1
ENSMUST00000031256.5
Aff1

AF4/FMR2 family, member 1

chr9_-_78587968 1.694 ENSMUST00000117645.1
ENSMUST00000119213.1
ENSMUST00000052441.5
Slc17a5


solute carrier family 17 (anion/sugar transporter), member 5


chr10_+_79854618 1.674 ENSMUST00000165704.1
Ptbp1
polypyrimidine tract binding protein 1
chrX_-_164027965 1.673 ENSMUST00000033739.4
Car5b
carbonic anhydrase 5b, mitochondrial
chrX_+_141475385 1.671 ENSMUST00000112931.1
ENSMUST00000112930.1
Col4a5

collagen, type IV, alpha 5

chr1_-_97977233 1.669 ENSMUST00000161567.1
Pam
peptidylglycine alpha-amidating monooxygenase
chr13_-_60177357 1.635 ENSMUST00000065086.4
Gas1
growth arrest specific 1
chr6_+_125049952 1.613 ENSMUST00000088294.5
ENSMUST00000032481.7
Acrbp

proacrosin binding protein

chr4_+_119814495 1.601 ENSMUST00000106307.2
Hivep3
human immunodeficiency virus type I enhancer binding protein 3
chr5_+_21186267 1.584 ENSMUST00000036031.8
Gsap
gamma-secretase activating protein
chrX_-_134161928 1.559 ENSMUST00000033611.4
Xkrx
X Kell blood group precursor related X linked
chr10_+_79854658 1.553 ENSMUST00000171599.1
ENSMUST00000095457.4
Ptbp1

polypyrimidine tract binding protein 1

chr16_-_43664145 1.551 ENSMUST00000096065.4
Tigit
T cell immunoreceptor with Ig and ITIM domains
chr3_+_84925476 1.536 ENSMUST00000107675.1
Fbxw7
F-box and WD-40 domain protein 7
chr12_+_32954179 1.487 ENSMUST00000020885.6
Sypl
synaptophysin-like protein
chr3_-_129831374 1.478 ENSMUST00000029643.8
Gar1
GAR1 ribonucleoprotein homolog (yeast)
chr3_+_89436736 1.431 ENSMUST00000146630.1
ENSMUST00000145753.1
Pbxip1

pre B cell leukemia transcription factor interacting protein 1

chrX_-_142306170 1.421 ENSMUST00000134825.2
Kcne1l
potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene
chr6_+_55836878 1.418 ENSMUST00000044729.6
Ccdc129
coiled-coil domain containing 129
chr12_+_52516077 1.408 ENSMUST00000110725.1
Arhgap5
Rho GTPase activating protein 5
chr12_-_91779129 1.391 ENSMUST00000170077.1
Ston2
stonin 2
chr11_+_101665541 1.381 ENSMUST00000039388.2
Arl4d
ADP-ribosylation factor-like 4D
chr11_-_119086221 1.371 ENSMUST00000026665.7
Cbx4
chromobox 4
chr14_+_65968483 1.367 ENSMUST00000022616.6
Clu
clusterin
chr8_+_46163733 1.359 ENSMUST00000110376.1
4933411K20Rik
RIKEN cDNA 4933411K20 gene
chr4_-_11981265 1.355 ENSMUST00000098260.2
Gm10604
predicted gene 10604
chr7_-_25250720 1.337 ENSMUST00000116343.2
ENSMUST00000045847.8
Erf

Ets2 repressor factor

chr5_+_91517615 1.330 ENSMUST00000040576.9
Parm1
prostate androgen-regulated mucin-like protein 1
chr6_-_28261907 1.317 ENSMUST00000115320.1
ENSMUST00000123098.1
ENSMUST00000115321.2
ENSMUST00000155494.1
Zfp800



zinc finger protein 800



chr6_-_115251839 1.313 ENSMUST00000032462.6
Timp4
tissue inhibitor of metalloproteinase 4
chr18_+_73863672 1.311 ENSMUST00000134847.1
Mro
maestro
chr7_+_45216671 1.299 ENSMUST00000134420.1
Tead2
TEA domain family member 2
chr9_+_107587711 1.296 ENSMUST00000010192.5
Ifrd2
interferon-related developmental regulator 2
chr5_-_73647713 1.273 ENSMUST00000081170.7
Sgcb
sarcoglycan, beta (dystrophin-associated glycoprotein)
chr3_-_82074639 1.263 ENSMUST00000029635.8
Gucy1b3
guanylate cyclase 1, soluble, beta 3
chr15_-_58135047 1.243 ENSMUST00000038194.3
Atad2
ATPase family, AAA domain containing 2
chrX_+_73483602 1.241 ENSMUST00000033741.8
ENSMUST00000169489.1
Bgn

biglycan

chr2_-_52335134 1.234 ENSMUST00000075301.3
Neb
nebulin
chr1_-_155232710 1.231 ENSMUST00000035914.3
BC034090
cDNA sequence BC034090
chr5_-_140389188 1.218 ENSMUST00000031539.7
Snx8
sorting nexin 8
chr13_-_45964964 1.208 ENSMUST00000180110.1
ENSMUST00000091628.3
ENSMUST00000167708.2
Atxn1


ataxin 1


chr1_-_133424377 1.192 ENSMUST00000153799.1
Sox13
SRY-box containing gene 13
chr1_-_133921393 1.186 ENSMUST00000048432.5
Prelp
proline arginine-rich end leucine-rich repeat
chr14_+_30879257 1.177 ENSMUST00000040715.6
Mustn1
musculoskeletal, embryonic nuclear protein 1
chr11_+_113619318 1.177 ENSMUST00000146390.2
ENSMUST00000106630.1
Sstr2

somatostatin receptor 2

chr2_+_84734050 1.150 ENSMUST00000090729.2
Ypel4
yippee-like 4 (Drosophila)
chr16_+_14705832 1.147 ENSMUST00000023356.6
Snai2
snail homolog 2 (Drosophila)
chr9_+_57130690 1.145 ENSMUST00000160147.1
ENSMUST00000161663.1
ENSMUST00000034836.9
ENSMUST00000161182.1
Man2c1



mannosidase, alpha, class 2C, member 1



chr13_+_24327415 1.125 ENSMUST00000167746.1
Cmah
cytidine monophospho-N-acetylneuraminic acid hydroxylase
chr1_-_189343704 1.108 ENSMUST00000180044.1
ENSMUST00000110920.1
Kcnk2

potassium channel, subfamily K, member 2

chr10_+_127759721 1.093 ENSMUST00000073639.5
Rdh1
retinol dehydrogenase 1 (all trans)
chr16_-_16560201 1.083 ENSMUST00000162045.1
ENSMUST00000162124.1
ENSMUST00000161861.1
Fgd4


FYVE, RhoGEF and PH domain containing 4


chr2_+_30078584 1.064 ENSMUST00000045246.7
Pkn3
protein kinase N3
chr2_-_75938407 1.056 ENSMUST00000099996.3
Ttc30b
tetratricopeptide repeat domain 30B
chr4_+_148160613 1.053 ENSMUST00000047951.8
Fbxo2
F-box protein 2
chr6_-_134632388 1.053 ENSMUST00000047443.3
Mansc1
MANSC domain containing 1
chr19_-_15924560 1.046 ENSMUST00000162053.1
Psat1
phosphoserine aminotransferase 1
chr14_-_31019055 1.039 ENSMUST00000037739.6
Gnl3
guanine nucleotide binding protein-like 3 (nucleolar)
chr2_-_27246814 1.035 ENSMUST00000149733.1
Sardh
sarcosine dehydrogenase
chr15_-_102722120 1.016 ENSMUST00000171838.1
Calcoco1
calcium binding and coiled coil domain 1
chr15_-_75894474 1.015 ENSMUST00000023237.6
Naprt1
nicotinate phosphoribosyltransferase domain containing 1
chr19_+_3323301 0.996 ENSMUST00000025835.4
Cpt1a
carnitine palmitoyltransferase 1a, liver
chr10_+_118860826 0.990 ENSMUST00000059966.4
4932442E05Rik
RIKEN cDNA 4932442E05 gene
chr15_-_89429851 0.980 ENSMUST00000023289.6
Chkb
choline kinase beta
chr11_-_67922136 0.977 ENSMUST00000021288.3
ENSMUST00000108677.1
Usp43

ubiquitin specific peptidase 43

chr7_-_80405425 0.973 ENSMUST00000107362.3
ENSMUST00000135306.1
Furin

furin (paired basic amino acid cleaving enzyme)

chr3_+_105973711 0.970 ENSMUST00000000573.2
Ovgp1
oviductal glycoprotein 1
chr6_+_80018877 0.970 ENSMUST00000147663.1
ENSMUST00000128718.1
ENSMUST00000126005.1
ENSMUST00000133918.1
Lrrtm4



leucine rich repeat transmembrane neuronal 4



chr14_-_20181773 0.967 ENSMUST00000024011.8
Kcnk5
potassium channel, subfamily K, member 5
chr4_+_15265798 0.967 ENSMUST00000062684.8
Tmem64
transmembrane protein 64
chr19_-_32388462 0.964 ENSMUST00000099514.3
Sgms1
sphingomyelin synthase 1
chr16_+_20591156 0.964 ENSMUST00000159780.1
Vwa5b2
von Willebrand factor A domain containing 5B2
chr2_+_26973416 0.935 ENSMUST00000014996.7
ENSMUST00000102891.3
Adamts13

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13

chr18_+_73859366 0.935 ENSMUST00000120033.1
ENSMUST00000179472.1
ENSMUST00000119239.1
Mro


maestro


chr15_+_3270767 0.925 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
Sepp1



selenoprotein P, plasma, 1



chr16_-_4559720 0.920 ENSMUST00000005862.7
Tfap4
transcription factor AP4
chr12_-_86079019 0.918 ENSMUST00000003687.6
Tgfb3
transforming growth factor, beta 3
chrX_+_56454871 0.911 ENSMUST00000039374.2
ENSMUST00000101553.2
Ddx26b

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

chr1_+_162570687 0.911 ENSMUST00000050010.4
ENSMUST00000150040.1
Vamp4

vesicle-associated membrane protein 4

chr2_-_140170528 0.908 ENSMUST00000046030.7
Esf1
ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
chr3_+_107877227 0.908 ENSMUST00000037375.8
Eps8l3
EPS8-like 3
chr3_+_96557950 0.900 ENSMUST00000074519.6
ENSMUST00000049093.7
Txnip

thioredoxin interacting protein

chr6_-_23132981 0.894 ENSMUST00000031707.7
Aass
aminoadipate-semialdehyde synthase
chr5_+_150673739 0.891 ENSMUST00000016569.4
ENSMUST00000038900.8
Pds5b

PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)

chr8_+_15011025 0.889 ENSMUST00000069399.6
Kbtbd11
kelch repeat and BTB (POZ) domain containing 11
chrX_+_101449078 0.884 ENSMUST00000033674.5
Itgb1bp2
integrin beta 1 binding protein 2
chr6_+_107529717 0.883 ENSMUST00000049285.8
Lrrn1
leucine rich repeat protein 1, neuronal
chr9_+_85842852 0.874 ENSMUST00000098500.3
Tpbg
trophoblast glycoprotein
chr15_-_97767798 0.874 ENSMUST00000129223.2
ENSMUST00000126854.2
ENSMUST00000135080.1
Rapgef3


Rap guanine nucleotide exchange factor (GEF) 3


chr2_+_31640037 0.867 ENSMUST00000113470.2
Prdm12
PR domain containing 12
chr15_-_71727815 0.866 ENSMUST00000022953.8
Fam135b
family with sequence similarity 135, member B
chr8_+_46739745 0.862 ENSMUST00000034041.7
Irf2
interferon regulatory factor 2
chr10_-_56228636 0.859 ENSMUST00000099739.3
Tbc1d32
TBC1 domain family, member 32
chr5_+_119834663 0.859 ENSMUST00000018407.6
Tbx5
T-box 5
chr16_-_17561240 0.854 ENSMUST00000065125.5
ENSMUST00000100123.3
ENSMUST00000023442.6
4930451C15Rik


RIKEN cDNA 4930451C15 gene


chr17_-_51826562 0.853 ENSMUST00000024720.4
ENSMUST00000129667.1
ENSMUST00000156051.1
ENSMUST00000169480.1
ENSMUST00000148559.1
Satb1




special AT-rich sequence binding protein 1




chr7_-_24208093 0.852 ENSMUST00000086006.5
Zfp111
zinc finger protein 111
chr7_+_141455198 0.850 ENSMUST00000164016.1
ENSMUST00000064151.6
ENSMUST00000169665.1
Pnpla2


patatin-like phospholipase domain containing 2


chr7_+_28180226 0.847 ENSMUST00000172467.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chrX_+_71663665 0.847 ENSMUST00000070449.5
Gpr50
G-protein-coupled receptor 50
chr15_-_97767644 0.846 ENSMUST00000128775.2
ENSMUST00000134885.2
Rapgef3

Rap guanine nucleotide exchange factor (GEF) 3

chr2_-_18392736 0.839 ENSMUST00000091418.5
ENSMUST00000166495.1
Dnajc1

DnaJ (Hsp40) homolog, subfamily C, member 1

chr6_+_21215472 0.838 ENSMUST00000081542.5
Kcnd2
potassium voltage-gated channel, Shal-related family, member 2
chr15_-_102722150 0.831 ENSMUST00000023818.3
Calcoco1
calcium binding and coiled coil domain 1
chr14_-_16249675 0.828 ENSMUST00000022311.4
Oxsm
3-oxoacyl-ACP synthase, mitochondrial
chrM_+_7005 0.821 ENSMUST00000082405.1
mt-Co2
mitochondrially encoded cytochrome c oxidase II
chr14_-_88471396 0.813 ENSMUST00000061628.5
Pcdh20
protocadherin 20
chr10_-_78487842 0.812 ENSMUST00000069431.4
Gm9978
predicted gene 9978
chr7_-_120202104 0.809 ENSMUST00000033198.5
Crym
crystallin, mu
chr1_+_87327044 0.802 ENSMUST00000173173.1
Gigyf2
GRB10 interacting GYF protein 2
chr11_-_23519181 0.800 ENSMUST00000020527.5
1700093K21Rik
RIKEN cDNA 1700093K21 gene
chr19_-_10881723 0.796 ENSMUST00000144681.1
Tmem109
transmembrane protein 109
chr1_-_121327672 0.795 ENSMUST00000159085.1
ENSMUST00000159125.1
ENSMUST00000161818.1
Insig2


insulin induced gene 2


chr4_-_155863362 0.795 ENSMUST00000030949.3
Tas1r3
taste receptor, type 1, member 3
chr4_+_155962292 0.793 ENSMUST00000024338.4
Fam132a
family with sequence similarity 132, member A
chr14_-_31830402 0.790 ENSMUST00000014640.7
Ankrd28
ankyrin repeat domain 28
chr6_+_80019008 0.783 ENSMUST00000126399.1
ENSMUST00000136421.1
Lrrtm4

leucine rich repeat transmembrane neuronal 4

chr13_+_83738874 0.781 ENSMUST00000052354.4
C130071C03Rik
RIKEN cDNA C130071C03 gene
chr1_-_128102412 0.774 ENSMUST00000112538.1
ENSMUST00000086614.5
Zranb3

zinc finger, RAN-binding domain containing 3

chr1_+_36307745 0.772 ENSMUST00000142319.1
ENSMUST00000097778.2
ENSMUST00000115031.1
ENSMUST00000115032.1
ENSMUST00000137906.1
ENSMUST00000115029.1
Arid5a





AT rich interactive domain 5A (MRF1-like)





chr13_+_83721357 0.758 ENSMUST00000131907.2
C130071C03Rik
RIKEN cDNA C130071C03 gene
chr4_-_149454971 0.756 ENSMUST00000030848.2
Rbp7
retinol binding protein 7, cellular
chr8_-_71381907 0.752 ENSMUST00000002466.8
Nr2f6
nuclear receptor subfamily 2, group F, member 6
chr3_+_35754121 0.752 ENSMUST00000108186.1
ENSMUST00000029257.8
Atp11b

ATPase, class VI, type 11B

chr16_-_16560046 0.751 ENSMUST00000172181.2
Fgd4
FYVE, RhoGEF and PH domain containing 4
chr7_-_127946725 0.743 ENSMUST00000118755.1
ENSMUST00000094026.3
Prss36

protease, serine, 36

chr7_-_127993831 0.735 ENSMUST00000033056.3
Pycard
PYD and CARD domain containing
chr19_-_23448322 0.735 ENSMUST00000036069.6
Mamdc2
MAM domain containing 2
chr11_-_95076797 0.720 ENSMUST00000145671.1
ENSMUST00000120375.1
Itga3

integrin alpha 3

chr7_+_25152456 0.719 ENSMUST00000098678.1
D930028M14Rik
RIKEN cDNA D930028M14 gene
chr5_+_64160207 0.718 ENSMUST00000101195.2
Tbc1d1
TBC1 domain family, member 1
chr14_+_55478753 0.715 ENSMUST00000022821.6
Dhrs4
dehydrogenase/reductase (SDR family) member 4
chr7_+_29071597 0.715 ENSMUST00000180926.1
Gm26604
predicted gene, 26604
chr5_-_72559599 0.709 ENSMUST00000074948.4
ENSMUST00000087216.5
Nfxl1

nuclear transcription factor, X-box binding-like 1

chr7_+_140763739 0.709 ENSMUST00000026552.7
Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
chr7_+_28180272 0.703 ENSMUST00000173223.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr2_+_130405256 0.698 ENSMUST00000110281.1
ENSMUST00000028898.3
1700020A23Rik

RIKEN cDNA 1700020A23 gene

chr11_+_102189620 0.692 ENSMUST00000070334.3
ENSMUST00000078975.7
G6pc3

glucose 6 phosphatase, catalytic, 3

chr19_+_7056731 0.689 ENSMUST00000040261.5
Macrod1
MACRO domain containing 1
chr14_+_32856756 0.674 ENSMUST00000053175.5
ENSMUST00000100721.2
Vstm4

V-set and transmembrane domain containing 4

chr7_-_127725616 0.672 ENSMUST00000076091.2
Ctf2
cardiotrophin 2
chr8_+_46163651 0.659 ENSMUST00000034048.6
ENSMUST00000145229.1
4933411K20Rik

RIKEN cDNA 4933411K20 gene

chr11_+_58307055 0.649 ENSMUST00000153510.2
Zfp692
zinc finger protein 692
chrX_+_48108912 0.645 ENSMUST00000114998.1
ENSMUST00000115000.3
Xpnpep2

X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound

chr16_+_93832121 0.645 ENSMUST00000044068.6
Morc3
microrchidia 3
chr1_-_121327734 0.644 ENSMUST00000160968.1
ENSMUST00000162582.1
Insig2

insulin induced gene 2

chr1_+_36511867 0.642 ENSMUST00000001166.7
ENSMUST00000097776.3
Cnnm3

cyclin M3

chr1_-_36535719 0.642 ENSMUST00000054665.4
Ankrd23
ankyrin repeat domain 23

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 16.1 GO:0042572 retinol metabolic process(GO:0042572)
1.4 4.1 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
1.3 4.0 GO:0006601 creatine biosynthetic process(GO:0006601)
1.3 5.1 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
1.2 6.1 GO:0003105 negative regulation of glomerular filtration(GO:0003105) positive regulation of NAD(P)H oxidase activity(GO:0033864) positive regulation of toll-like receptor 2 signaling pathway(GO:0034137)
1.1 3.2 GO:1990523 bone regeneration(GO:1990523)
1.0 5.0 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.8 4.7 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.7 4.4 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.6 1.8 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) negative regulation of regulatory T cell differentiation(GO:0045590) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.6 1.8 GO:0035622 intrahepatic bile duct development(GO:0035622) renal vesicle induction(GO:0072034)
0.5 1.6 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.5 2.4 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.4 1.7 GO:1904451 regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453)
0.4 4.3 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.4 1.3 GO:0036292 DNA rewinding(GO:0036292)
0.4 1.3 GO:0099548 trans-synaptic signaling by nitric oxide(GO:0099548)
0.4 1.1 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.4 1.1 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.3 1.0 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.3 3.8 GO:0009404 toxin metabolic process(GO:0009404)
0.3 1.0 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.3 1.0 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.3 1.5 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.3 0.9 GO:0003032 detection of oxygen(GO:0003032)
0.3 0.9 GO:0006553 lysine metabolic process(GO:0006553)
0.3 1.5 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.3 2.9 GO:0090527 actin filament reorganization(GO:0090527)
0.3 0.8 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.3 1.3 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.3 3.2 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.3 1.8 GO:0030035 microspike assembly(GO:0030035)
0.2 1.0 GO:0042373 vitamin K metabolic process(GO:0042373)
0.2 0.7 GO:0002586 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.2 1.0 GO:0090472 dibasic protein processing(GO:0090472)
0.2 1.9 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.2 3.8 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.2 1.2 GO:1902732 positive regulation of chondrocyte proliferation(GO:1902732)
0.2 0.7 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.2 1.4 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.2 0.7 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.2 0.7 GO:0002331 pre-B cell allelic exclusion(GO:0002331) signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434) regulation of microglial cell activation(GO:1903978) telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.2 0.8 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.2 1.8 GO:0006013 mannose metabolic process(GO:0006013)
0.2 1.4 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.2 0.8 GO:0070327 thyroid hormone transport(GO:0070327)
0.2 0.6 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.2 0.8 GO:2000318 positive regulation of T-helper 17 type immune response(GO:2000318)
0.2 1.3 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.2 1.7 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2 2.6 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
0.2 0.5 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.2 1.6 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.2 0.9 GO:1900109 regulation of histone H3-K9 dimethylation(GO:1900109)
0.2 1.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.2 1.9 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.2 0.7 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.2 2.2 GO:0001675 acrosome assembly(GO:0001675)
0.2 0.5 GO:0006083 acetate metabolic process(GO:0006083)
0.2 0.8 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.2 1.6 GO:0042473 outer ear morphogenesis(GO:0042473)
0.2 1.0 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.2 1.3 GO:0043383 negative T cell selection(GO:0043383) negative thymic T cell selection(GO:0045060)
0.2 0.8 GO:0050912 detection of chemical stimulus involved in sensory perception(GO:0050907) detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
0.2 0.8 GO:0042701 progesterone secretion(GO:0042701)
0.2 0.5 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.2 1.8 GO:0014842 regulation of skeletal muscle satellite cell proliferation(GO:0014842) regulation of skeletal muscle cell proliferation(GO:0014857)
0.1 0.9 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.6 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.1 1.9 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.1 0.4 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.1 0.4 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1 0.3 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.1 0.3 GO:0060648 mammary gland bud morphogenesis(GO:0060648) negative regulation of determination of dorsal identity(GO:2000016)
0.1 2.2 GO:0048240 sperm capacitation(GO:0048240)
0.1 1.8 GO:0001573 ganglioside metabolic process(GO:0001573)
0.1 0.2 GO:0035106 operant conditioning(GO:0035106)
0.1 1.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.4 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.1 1.8 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.1 2.5 GO:0006721 terpenoid metabolic process(GO:0006721)
0.1 1.5 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.1 1.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.3 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1 1.0 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 1.2 GO:0030432 peristalsis(GO:0030432)
0.1 3.7 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 0.4 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.1 1.3 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.1 0.9 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.1 0.3 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 1.6 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.1 0.9 GO:0002347 response to tumor cell(GO:0002347)
0.1 0.3 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100) cellular magnesium ion homeostasis(GO:0010961) vein smooth muscle contraction(GO:0014826)
0.1 1.5 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 1.2 GO:0046643 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.1 0.6 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.1 0.3 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.1 1.4 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.3 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.1 1.0 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1 1.9 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 3.2 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 2.1 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 2.7 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.1 0.4 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 1.3 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.1 0.5 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.9 GO:0090003 regulation of Golgi to plasma membrane protein transport(GO:0042996) regulation of establishment of protein localization to plasma membrane(GO:0090003)
0.1 2.6 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.1 0.5 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 1.6 GO:0045475 locomotor rhythm(GO:0045475)
0.1 0.4 GO:0048703 embryonic viscerocranium morphogenesis(GO:0048703)
0.1 0.2 GO:0021852 pyramidal neuron migration(GO:0021852)
0.1 0.2 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.1 0.6 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.1 7.7 GO:0051592 response to calcium ion(GO:0051592)
0.1 1.6 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.1 0.3 GO:1905169 protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171)
0.1 0.6 GO:0048625 embryonic hindgut morphogenesis(GO:0048619) myoblast fate commitment(GO:0048625)
0.1 0.2 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.1 1.3 GO:0048368 lateral mesoderm development(GO:0048368)
0.1 0.3 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.1 0.5 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 0.6 GO:0060297 regulation of sarcomere organization(GO:0060297)
0.1 0.9 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.1 0.2 GO:0046618 drug export(GO:0046618)
0.1 0.2 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 0.5 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1 0.6 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.1 1.2 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.1 1.9 GO:0007520 myoblast fusion(GO:0007520)
0.1 0.2 GO:0033580 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
0.1 0.8 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1 0.3 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.1 0.3 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1 0.3 GO:0032429 regulation of phospholipase A2 activity(GO:0032429)
0.1 0.2 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.1 0.5 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 0.5 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 0.2 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.1 1.4 GO:0016925 protein sumoylation(GO:0016925)
0.1 0.5 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 3.7 GO:0048663 neuron fate commitment(GO:0048663)
0.0 0.3 GO:0021593 rhombomere morphogenesis(GO:0021593)
0.0 0.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 1.1 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 1.0 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.3 GO:0032264 IMP salvage(GO:0032264)
0.0 3.1 GO:0007569 cell aging(GO:0007569)
0.0 0.3 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 1.7 GO:1901264 carbohydrate derivative transport(GO:1901264)
0.0 0.4 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 1.9 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.2 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.0 0.1 GO:0046210 nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.0 0.2 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.0 0.6 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 1.4 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.2 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.5 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.1 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.9 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.1 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.0 0.1 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.0 0.6 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.3 GO:0007602 phototransduction(GO:0007602)
0.0 0.4 GO:0032060 bleb assembly(GO:0032060)
0.0 0.3 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.0 0.5 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.5 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 1.8 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.4 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.1 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.1 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.3 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.0 0.5 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:0014029 neural crest formation(GO:0014029)
0.0 0.1 GO:0042891 antibiotic transport(GO:0042891)
0.0 1.1 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.1 GO:0015938 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034)
0.0 0.1 GO:0090205 positive regulation of cholesterol biosynthetic process(GO:0045542) positive regulation of cholesterol metabolic process(GO:0090205)
0.0 0.1 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.2 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 1.5 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.3 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.1 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.2 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.4 GO:0044030 regulation of DNA methylation(GO:0044030)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.3 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0003016 respiratory system process(GO:0003016)
0.0 0.0 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.1 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.0 0.1 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.0 GO:0050904 diapedesis(GO:0050904)
0.0 0.3 GO:0045214 sarcomere organization(GO:0045214)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 6.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.8 3.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.4 1.3 GO:0071438 integrin alpha3-beta1 complex(GO:0034667) invadopodium membrane(GO:0071438)
0.4 1.3 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.4 1.7 GO:0097574 lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795)
0.4 1.5 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.4 1.5 GO:0001651 dense fibrillar component(GO:0001651)
0.3 1.7 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.3 1.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 1.9 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.2 0.4 GO:0016011 dystroglycan complex(GO:0016011)
0.2 1.8 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 1.4 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.2 1.1 GO:0044305 calyx of Held(GO:0044305)
0.2 0.7 GO:0061702 inflammasome complex(GO:0061702)
0.2 3.3 GO:0031527 filopodium membrane(GO:0031527)
0.2 2.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.2 0.5 GO:0043512 inhibin A complex(GO:0043512)
0.1 2.6 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.1 2.4 GO:0005605 basal lamina(GO:0005605)
0.1 2.5 GO:0002080 acrosomal membrane(GO:0002080)
0.1 0.5 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.1 5.2 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 1.0 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 0.6 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.1 0.4 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 1.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 1.1 GO:0042555 MCM complex(GO:0042555)
0.1 0.7 GO:0032009 early phagosome(GO:0032009)
0.1 0.4 GO:1990761 growth cone lamellipodium(GO:1990761)
0.1 1.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.1 1.2 GO:1990635 proximal dendrite(GO:1990635)
0.1 1.4 GO:0035102 PRC1 complex(GO:0035102)
0.1 0.6 GO:0042629 mast cell granule(GO:0042629)
0.1 5.1 GO:0031526 brush border membrane(GO:0031526)
0.1 1.3 GO:0030018 Z disc(GO:0030018)
0.1 1.7 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.1 GO:0070761 pre-snoRNP complex(GO:0070761)
0.1 0.3 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 2.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.5 GO:0031209 SCAR complex(GO:0031209)
0.1 0.6 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 1.1 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 0.8 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 4.2 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 1.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 4.2 GO:0030175 filopodium(GO:0030175)
0.0 0.7 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.3 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 1.8 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.1 GO:0045098 type III intermediate filament(GO:0045098)
0.0 1.1 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.2 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.8 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 4.7 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 1.0 GO:0002102 podosome(GO:0002102)
0.0 1.2 GO:0043596 nuclear replication fork(GO:0043596)
0.0 11.7 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.5 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.8 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 7.0 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 1.1 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 1.2 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.2 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.7 GO:1990391 DNA repair complex(GO:1990391)
0.0 1.8 GO:0016605 PML body(GO:0016605)
0.0 1.4 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 1.1 GO:0005811 lipid particle(GO:0005811)
0.0 0.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 1.0 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.4 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.3 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.7 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.4 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 1.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 1.6 GO:0031012 extracellular matrix(GO:0031012)
0.0 15.9 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 16.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
1.5 6.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.8 5.0 GO:0035184 histone threonine kinase activity(GO:0035184)
0.6 4.4 GO:0070492 oligosaccharide binding(GO:0070492)
0.6 1.7 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.5 3.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.5 1.0 GO:0004568 chitinase activity(GO:0004568)
0.4 2.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.4 3.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.4 1.1 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.4 2.6 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.3 4.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.3 1.0 GO:0046997 sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.3 1.5 GO:0050816 phosphothreonine binding(GO:0050816)
0.3 0.9 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.3 0.8 GO:0008502 melatonin receptor activity(GO:0008502)
0.3 0.8 GO:0008527 taste receptor activity(GO:0008527)
0.2 1.0 GO:0004103 choline kinase activity(GO:0004103)
0.2 0.7 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.2 0.7 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.2 0.9 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.2 2.2 GO:0016004 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.2 2.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.2 1.5 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.2 0.8 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.2 0.8 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.2 1.0 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.2 1.8 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.2 4.7 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.2 1.0 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.2 2.7 GO:0016805 dipeptidase activity(GO:0016805)
0.2 1.4 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.2 3.1 GO:0051393 alpha-actinin binding(GO:0051393)
0.2 1.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.2 5.4 GO:0001223 transcription coactivator binding(GO:0001223)
0.2 1.1 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.2 3.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.4 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.1 0.7 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 1.2 GO:0034046 poly(G) binding(GO:0034046)
0.1 1.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.8 GO:0019841 retinal binding(GO:0016918) retinol binding(GO:0019841)
0.1 0.8 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 3.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 3.0 GO:0070064 proline-rich region binding(GO:0070064)
0.1 1.3 GO:0036310 annealing helicase activity(GO:0036310)
0.1 1.7 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 1.3 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 0.3 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.1 5.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.4 GO:0034481 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537) chondroitin sulfotransferase activity(GO:0034481)
0.1 0.7 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 1.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 1.4 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.1 0.8 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 1.0 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 1.8 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 0.6 GO:0031432 titin binding(GO:0031432)
0.1 1.7 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.5 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 1.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 0.7 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.1 0.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.4 GO:0009374 biotin binding(GO:0009374)
0.1 0.4 GO:0001849 complement component C1q binding(GO:0001849)
0.1 1.4 GO:0051787 misfolded protein binding(GO:0051787)
0.1 0.2 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.1 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.6 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 0.5 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 1.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559) phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0 0.3 GO:0036122 BMP binding(GO:0036122) BMP receptor activity(GO:0098821)
0.0 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 1.8 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 9.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.3 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.3 GO:0048256 flap endonuclease activity(GO:0048256)
0.0 1.4 GO:0032183 SUMO binding(GO:0032183)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.6 GO:0048038 quinone binding(GO:0048038)
0.0 0.9 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.8 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.2 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.0 1.7 GO:1901505 carbohydrate derivative transporter activity(GO:1901505)
0.0 0.8 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 1.9 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.8 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 3.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.6 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.7 GO:0004697 protein kinase C activity(GO:0004697)
0.0 1.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0016675 oxidoreductase activity, acting on a heme group of donors(GO:0016675)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 1.1 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 1.3 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 6.0 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.9 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.4 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.6 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 3.2 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.5 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 1.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.4 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.9 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.1 GO:0042895 antibiotic transporter activity(GO:0042895)
0.0 0.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.3 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.1 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.0 0.9 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.4 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.5 GO:0050661 NADP binding(GO:0050661)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.9 GO:0030507 spectrin binding(GO:0030507)
0.0 0.3 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 0.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.9 GO:0043022 ribosome binding(GO:0043022)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.5 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 0.2 GO:0051010 myosin V binding(GO:0031489) microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0098505 single-stranded telomeric DNA binding(GO:0043047) G-rich strand telomeric DNA binding(GO:0098505)
0.0 1.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.6 GO:0003730 mRNA 3'-UTR binding(GO:0003730)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.4 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.3 5.0 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.3 15.9 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 2.6 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.2 1.0 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.2 4.5 ST_GA12_PATHWAY G alpha 12 Pathway
0.1 3.7 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.1 1.7 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.1 4.1 PID_RAS_PATHWAY Regulation of Ras family activation
0.1 0.4 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.1 5.1 PID_RAC1_PATHWAY RAC1 signaling pathway
0.1 2.4 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 2.2 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.1 0.4 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.1 0.4 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.1 1.7 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.1 1.3 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.1 1.9 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 1.6 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 5.7 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.9 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 0.4 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 1.0 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.4 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.0 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.2 PID_ATR_PATHWAY ATR signaling pathway
0.0 0.6 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 3.9 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 1.0 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.4 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 0.5 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 0.9 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 0.2 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.5 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 1.9 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.7 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 0.1 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.0 0.5 PID_PI3KCI_PATHWAY Class I PI3K signaling events
0.0 0.2 PID_BARD1_PATHWAY BARD1 signaling events
0.0 0.5 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.2 NABA_MATRISOME_ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.3 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.2 1.6 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.2 6.1 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.2 1.1 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.2 1.6 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 1.1 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 3.8 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.2 2.1 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 1.4 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.1 2.7 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 0.5 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.1 9.8 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 1.2 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.1 1.0 REACTOME_RORA_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in RORA Activates Circadian Expression
0.1 0.5 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 5.6 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 0.4 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 2.2 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 4.5 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.1 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.1 0.3 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 0.7 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 0.8 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 0.7 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 0.4 REACTOME_ELONGATION_ARREST_AND_RECOVERY Genes involved in Elongation arrest and recovery
0.0 2.1 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 1.8 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.4 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.4 REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.4 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.0 1.5 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.4 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 5.1 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.6 REACTOME_REGULATION_OF_HYPOXIA_INDUCIBLE_FACTOR_HIF_BY_OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.5 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 1.7 REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.0 3.2 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.0 1.0 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.7 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.7 REACTOME_MUSCLE_CONTRACTION Genes involved in Muscle contraction
0.0 0.5 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.7 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.0 0.4 REACTOME_DOUBLE_STRAND_BREAK_REPAIR Genes involved in Double-Strand Break Repair
0.0 0.4 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.9 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.2 REACTOME_G_ALPHA1213_SIGNALLING_EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.8 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)