Motif ID: Ar

Z-value: 1.137


Transcription factors associated with Ar:

Gene SymbolEntrez IDGene Name
Ar ENSMUSG00000046532.7 Ar



Activity profile for motif Ar.

activity profile for motif Ar


Sorted Z-values histogram for motif Ar

Sorted Z-values for motif Ar



Network of associatons between targets according to the STRING database.



First level regulatory network of Ar

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_5725639 10.157 ENSMUST00000115556.1
ENSMUST00000115555.1
ENSMUST00000115559.3
 Dync1i1


dynein cytoplasmic 1 intermediate chain 1


chr6_+_5725812 9.812 ENSMUST00000115554.1
ENSMUST00000153942.1
 Dync1i1

dynein cytoplasmic 1 intermediate chain 1

chr3_+_117575268 7.654 ENSMUST00000039564.6
 4833424O15Rik
RIKEN cDNA 4833424O15 gene
chr12_-_25096080 7.587 ENSMUST00000020974.6
 Id2
inhibitor of DNA binding 2
chr3_-_113577743 6.548 ENSMUST00000067980.5
 Amy1
amylase 1, salivary
chr3_-_113574242 6.361 ENSMUST00000142505.2
 Amy1
amylase 1, salivary
chr3_-_113574758 6.279 ENSMUST00000106540.1
 Amy1
amylase 1, salivary
chr4_-_136892867 6.241 ENSMUST00000046332.5
 C1qc
complement component 1, q subcomponent, C chain
chr12_+_74297474 5.977 ENSMUST00000072100.3
 Dbpht2
DNA binding protein with his-thr domain
chr10_-_117282262 5.952 ENSMUST00000092163.7
 Lyz2
lysozyme 2
chr8_+_95703037 5.662 ENSMUST00000073139.7
ENSMUST00000080666.7
 Ndrg4

N-myc downstream regulated gene 4

chr17_+_56764738 5.480 ENSMUST00000007747.8
 Dus3l
dihydrouridine synthase 3-like (S. cerevisiae)
chr19_+_8664005 4.923 ENSMUST00000035444.3
ENSMUST00000163785.1
 Chrm1

cholinergic receptor, muscarinic 1, CNS

chr5_+_17574726 4.867 ENSMUST00000169603.1
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr10_-_86732409 4.841 ENSMUST00000070435.4
 Fabp3-ps1
fatty acid binding protein 3, muscle and heart, pseudogene 1
chr1_-_173942445 4.827 ENSMUST00000042228.8
ENSMUST00000081216.5
ENSMUST00000129829.1
ENSMUST00000123708.1
ENSMUST00000111210.2
 Ifi203



Mndal
interferon activated gene 203



myeloid nuclear differentiation antigen like
chr7_-_46179929 4.429 ENSMUST00000033123.6
 Abcc8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr11_-_98053415 4.349 ENSMUST00000017544.2
 Stac2
SH3 and cysteine rich domain 2
chr15_+_89568322 4.336 ENSMUST00000023295.2
 Acr
acrosin prepropeptide
chr14_-_7483762 4.228 ENSMUST00000164366.1
 Gm3752
predicted gene 3752

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 140 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.8 20.0 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
1.5 7.6 GO:0045578 negative regulation of B cell differentiation(GO:0045578) epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.7 7.5 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 7.2 GO:0016052 carbohydrate catabolic process(GO:0016052)
1.7 6.7 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.9 6.2 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
2.0 6.0 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.4 5.7 GO:2001135 regulation of endocytic recycling(GO:2001135)
1.0 4.9 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.8 4.9 GO:0003350 pulmonary myocardium development(GO:0003350)
0.1 4.8 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.9 4.5 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
1.5 4.4 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
1.4 4.3 GO:0007341 penetration of zona pellucida(GO:0007341)
1.1 4.2 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.5 4.0 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 4.0 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.8 3.9 GO:0070459 prolactin secretion(GO:0070459)
0.0 3.7 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.1 3.6 GO:0015914 phospholipid transport(GO:0015914)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 69 entries
Log-likelihood per target Total log-likelihoodTermDescription
6.7 20.0 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
0.0 17.2 GO:0005615 extracellular space(GO:0005615)
0.4 11.6 GO:0033270 paranode region of axon(GO:0033270)
0.1 11.5 GO:0072562 blood microparticle(GO:0072562)
0.0 6.1 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
1.2 6.0 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 5.9 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.2 4.9 GO:0032279 asymmetric synapse(GO:0032279)
0.6 4.5 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
1.1 4.4 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 4.2 GO:0002080 acrosomal membrane(GO:0002080)
1.0 3.9 GO:0097487 vesicle lumen(GO:0031983) multivesicular body, internal vesicle(GO:0097487)
0.2 3.6 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 3.6 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 3.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 3.6 GO:0043204 perikaryon(GO:0043204)
0.1 3.5 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 3.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 2.6 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 2.6 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 99 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.2 20.0 GO:0045504 dynein heavy chain binding(GO:0045504)
6.4 19.2 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.1 11.6 GO:0044325 ion channel binding(GO:0044325)
0.2 8.6 GO:0030507 spectrin binding(GO:0030507)
2.0 6.0 GO:0003796 lysozyme activity(GO:0003796)
1.0 4.9 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.4 4.9 GO:0038191 neuropilin binding(GO:0038191)
0.0 4.9 GO:0003924 GTPase activity(GO:0003924)
0.3 4.5 GO:0043495 protein anchor(GO:0043495)
0.3 4.3 GO:0005537 mannose binding(GO:0005537)
1.4 4.2 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
1.1 4.2 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 4.1 GO:0001047 core promoter binding(GO:0001047)
0.4 4.0 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.3 4.0 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
1.3 3.9 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 3.8 GO:0017022 myosin binding(GO:0017022)
0.3 3.6 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
1.2 3.5 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.7 3.4 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 13.0 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.1 12.7 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.2 6.5 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 5.7 PID_FOXO_PATHWAY FoxO family signaling
0.1 4.0 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.3 3.9 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.1 3.2 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.1 2.4 ST_INTERLEUKIN_4_PATHWAY Interleukin 4 (IL-4) Pathway
0.1 2.4 ST_G_ALPHA_I_PATHWAY G alpha i Pathway
0.2 2.2 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 1.9 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.1 1.9 PID_TCPTP_PATHWAY Signaling events mediated by TCPTP
0.1 1.8 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.1 1.3 PID_LYMPH_ANGIOGENESIS_PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 1.3 PID_IL2_1PATHWAY IL2-mediated signaling events
0.0 1.3 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.1 1.2 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 1.1 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.0 1.1 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.0 1.0 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 17.9 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.2 8.6 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
1.0 5.7 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 5.6 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 5.3 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.4 4.9 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.2 4.7 REACTOME_GRB2_EVENTS_IN_ERBB2_SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.6 4.2 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 3.6 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.5 3.2 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.2 3.0 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.1 3.0 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 2.5 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.1 2.4 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 2.2 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 2.0 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.2 1.9 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.7 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.1 1.6 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.2 1.5 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC