Motif ID: Arid3a

Z-value: 0.509


Transcription factors associated with Arid3a:

Gene SymbolEntrez IDGene Name
Arid3a ENSMUSG00000019564.6 Arid3a

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Arid3amm10_v2_chr10_+_79927330_799273700.095.0e-01Click!


Activity profile for motif Arid3a.

activity profile for motif Arid3a


Sorted Z-values histogram for motif Arid3a

Sorted Z-values for motif Arid3a



Network of associatons between targets according to the STRING database.



First level regulatory network of Arid3a

PNG image of the network

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Top targets:


Showing 1 to 20 of 93 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_85741389 2.934 ENSMUST00000094148.4
 Fam160a1
family with sequence similarity 160, member A1
chr4_+_139923349 2.061 ENSMUST00000128563.1
 Gm13028
predicted gene 13028
chr15_-_3583191 1.931 ENSMUST00000069451.4
 Ghr
growth hormone receptor
chr4_-_87806276 1.798 ENSMUST00000148059.1
 Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr4_-_87806296 1.762 ENSMUST00000126353.1
ENSMUST00000149357.1
 Mllt3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr17_+_3532554 1.488 ENSMUST00000168560.1
 Cldn20
claudin 20
chr16_+_43510267 1.391 ENSMUST00000114695.2
 Zbtb20
zinc finger and BTB domain containing 20
chr11_-_116654245 1.373 ENSMUST00000021166.5
 Cygb
cytoglobin
chr10_+_69533761 1.278 ENSMUST00000182884.1
 Ank3
ankyrin 3, epithelial
chr1_+_179961110 1.203 ENSMUST00000076687.5
ENSMUST00000097450.3
 Cdc42bpa

CDC42 binding protein kinase alpha

chr10_+_69533803 1.190 ENSMUST00000182155.1
ENSMUST00000183169.1
ENSMUST00000183148.1
 Ank3


ankyrin 3, epithelial


chr8_+_84415348 1.189 ENSMUST00000121390.1
ENSMUST00000122053.1
 Cacna1a

calcium channel, voltage-dependent, P/Q type, alpha 1A subunit

chr2_-_32982007 1.089 ENSMUST00000028129.7
 Slc2a8
solute carrier family 2, (facilitated glucose transporter), member 8
chr1_-_158958367 1.056 ENSMUST00000159861.2
 Pappa2
pappalysin 2
chr5_-_70842617 1.030 ENSMUST00000031119.1
 Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr1_+_17145357 0.969 ENSMUST00000026879.7
 Gdap1
ganglioside-induced differentiation-associated-protein 1
chr15_-_3583146 0.953 ENSMUST00000110698.2
 Ghr
growth hormone receptor
chr18_+_35770318 0.948 ENSMUST00000165299.1
 Gm16490
predicted gene 16490
chrX_+_163911401 0.940 ENSMUST00000140845.1
 Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr6_+_51544513 0.934 ENSMUST00000179365.1
ENSMUST00000114439.1
 Snx10

sorting nexin 10


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 3.6 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.7 2.9 GO:0000255 allantoin metabolic process(GO:0000255)
0.2 2.5 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 2.1 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.3 1.4 GO:0015671 oxygen transport(GO:0015671)
0.0 1.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.4 1.2 GO:0050883 regulation of sulfur amino acid metabolic process(GO:0031335) musculoskeletal movement, spinal reflex action(GO:0050883)
0.0 1.1 GO:0046323 glucose import(GO:0046323)
0.0 1.0 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 1.0 GO:0008053 mitochondrial fusion(GO:0008053)
0.3 0.9 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.9 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.9 GO:0060612 adipose tissue development(GO:0060612)
0.2 0.8 GO:0035617 stress granule disassembly(GO:0035617) plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386) regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.8 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.7 GO:1902995 apolipoprotein A-I-mediated signaling pathway(GO:0038027) regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995) positive regulation of apoptotic cell clearance(GO:2000427)
0.1 0.6 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.6 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.5 GO:0007257 activation of JUN kinase activity(GO:0007257)

Gene overrepresentation in cellular_component category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.6 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 2.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 2.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 2.1 GO:0042641 actomyosin(GO:0042641)
0.0 1.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.0 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 1.0 GO:0034707 chloride channel complex(GO:0034707)
0.3 0.9 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.9 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.9 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.8 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.7 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.6 GO:0031143 pseudopodium(GO:0031143)
0.0 0.5 GO:0030673 axolemma(GO:0030673)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.1 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.9 GO:0017046 peptide hormone binding(GO:0017046)
0.0 2.5 GO:0030507 spectrin binding(GO:0030507)
0.3 1.4 GO:0004096 catalase activity(GO:0004096)
0.1 1.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 1.1 GO:0005536 glucose binding(GO:0005536)
0.1 1.0 GO:0050811 GABA-A receptor activity(GO:0004890) GABA receptor binding(GO:0050811)
0.0 1.0 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 0.9 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 0.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.8 GO:0099609 microtubule lateral binding(GO:0099609)
0.0 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.2 0.7 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.2 0.6 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.1 0.6 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.5 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.3 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0 0.2 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)

Gene overrepresentation in C2:CP category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.9 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 2.1 PID_CDC42_PATHWAY CDC42 signaling events
0.0 0.9 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 0.8 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 0.6 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.5 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.3 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 2.9 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.1 2.5 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.5 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 1.2 REACTOME_REGULATION_OF_INSULIN_SECRETION Genes involved in Regulation of Insulin Secretion
0.1 1.1 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 0.9 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.9 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.8 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.7 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.6 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.2 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins