Motif ID: Arid3a

Z-value: 0.509


Transcription factors associated with Arid3a:

Gene SymbolEntrez IDGene Name
Arid3a ENSMUSG00000019564.6 Arid3a

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Arid3amm10_v2_chr10_+_79927330_799273700.095.0e-01Click!


Activity profile for motif Arid3a.

activity profile for motif Arid3a


Sorted Z-values histogram for motif Arid3a

Sorted Z-values for motif Arid3a



Network of associatons between targets according to the STRING database.



First level regulatory network of Arid3a

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_85741389 2.934 ENSMUST00000094148.4
 Fam160a1
family with sequence similarity 160, member A1
chr4_+_139923349 2.061 ENSMUST00000128563.1
 Gm13028
predicted gene 13028
chr15_-_3583191 1.931 ENSMUST00000069451.4
 Ghr
growth hormone receptor
chr4_-_87806276 1.798 ENSMUST00000148059.1
 Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr4_-_87806296 1.762 ENSMUST00000126353.1
ENSMUST00000149357.1
 Mllt3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr17_+_3532554 1.488 ENSMUST00000168560.1
 Cldn20
claudin 20
chr16_+_43510267 1.391 ENSMUST00000114695.2
 Zbtb20
zinc finger and BTB domain containing 20
chr11_-_116654245 1.373 ENSMUST00000021166.5
 Cygb
cytoglobin
chr10_+_69533761 1.278 ENSMUST00000182884.1
 Ank3
ankyrin 3, epithelial
chr1_+_179961110 1.203 ENSMUST00000076687.5
ENSMUST00000097450.3
 Cdc42bpa

CDC42 binding protein kinase alpha

chr10_+_69533803 1.190 ENSMUST00000182155.1
ENSMUST00000183169.1
ENSMUST00000183148.1
 Ank3


ankyrin 3, epithelial


chr8_+_84415348 1.189 ENSMUST00000121390.1
ENSMUST00000122053.1
 Cacna1a

calcium channel, voltage-dependent, P/Q type, alpha 1A subunit

chr2_-_32982007 1.089 ENSMUST00000028129.7
 Slc2a8
solute carrier family 2, (facilitated glucose transporter), member 8
chr1_-_158958367 1.056 ENSMUST00000159861.2
 Pappa2
pappalysin 2
chr5_-_70842617 1.030 ENSMUST00000031119.1
 Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr1_+_17145357 0.969 ENSMUST00000026879.7
 Gdap1
ganglioside-induced differentiation-associated-protein 1
chr15_-_3583146 0.953 ENSMUST00000110698.2
 Ghr
growth hormone receptor
chr18_+_35770318 0.948 ENSMUST00000165299.1
 Gm16490
predicted gene 16490
chrX_+_163911401 0.940 ENSMUST00000140845.1
 Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr6_+_51544513 0.934 ENSMUST00000179365.1
ENSMUST00000114439.1
 Snx10

sorting nexin 10

chr6_+_143285988 0.930 ENSMUST00000160951.1
 D6Ertd474e
DNA segment, Chr 6, ERATO Doi 474, expressed
chr7_+_66365905 0.879 ENSMUST00000107486.1
 Gm10974
predicted gene 10974
chr1_+_179960472 0.868 ENSMUST00000097453.2
ENSMUST00000111117.1
 Cdc42bpa

CDC42 binding protein kinase alpha

chr11_-_80377975 0.857 ENSMUST00000179332.1
ENSMUST00000103225.4
ENSMUST00000134274.1
 5730455P16Rik


RIKEN cDNA 5730455P16 gene


chr2_-_175327598 0.806 ENSMUST00000109050.2
 Gm4631
predicted gene 4631
chr1_+_60181495 0.703 ENSMUST00000160834.1
 Nbeal1
neurobeachin like 1
chr2_+_3770673 0.689 ENSMUST00000177037.1
 Fam107b
family with sequence similarity 107, member B
chr10_+_79996479 0.682 ENSMUST00000132517.1
 Abca7
ATP-binding cassette, sub-family A (ABC1), member 7
chr4_+_141368116 0.644 ENSMUST00000006380.4
 Fam131c
family with sequence similarity 131, member C
chr1_-_150392719 0.630 ENSMUST00000006167.6
ENSMUST00000094477.2
ENSMUST00000097547.3
 BC003331


cDNA sequence BC003331


chr14_+_120275669 0.621 ENSMUST00000088419.6
ENSMUST00000167459.1
 Mbnl2

muscleblind-like 2

chr19_+_58728887 0.618 ENSMUST00000048644.5
 Pnliprp1
pancreatic lipase related protein 1
chr12_-_24493656 0.612 ENSMUST00000073088.2
 Gm16372
predicted pseudogene 16372
chr12_-_4769217 0.595 ENSMUST00000053458.5
 Fam228b
family with sequence similarity 228, member B
chr12_+_4769375 0.578 ENSMUST00000178879.1
 Pfn4
profilin family, member 4
chr7_+_99594605 0.568 ENSMUST00000162290.1
 Arrb1
arrestin, beta 1
chr18_+_36939178 0.565 ENSMUST00000115662.2
 Pcdha2
protocadherin alpha 2
chr5_-_23616528 0.557 ENSMUST00000088392.4
 Srpk2
serine/arginine-rich protein specific kinase 2
chr16_-_4679703 0.523 ENSMUST00000038552.6
ENSMUST00000090480.4
 Coro7

coronin 7

chr3_+_32436376 0.486 ENSMUST00000108242.1
 Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr9_+_108392820 0.480 ENSMUST00000035234.4
 1700102P08Rik
RIKEN cDNA 1700102P08 gene
chr12_+_65225513 0.471 ENSMUST00000046331.4
 Wdr20b
WD repeat domain 20b
chr7_+_118597295 0.441 ENSMUST00000121715.1
ENSMUST00000098088.4
 Tmc5

transmembrane channel-like gene family 5

chr18_-_6241470 0.439 ENSMUST00000163210.1
 Kif5b
kinesin family member 5B
chr10_-_100589205 0.425 ENSMUST00000054471.8
 4930430F08Rik
RIKEN cDNA 4930430F08 gene
chr3_+_30602056 0.414 ENSMUST00000047502.7
 Mynn
myoneurin
chr9_+_114731177 0.404 ENSMUST00000035007.8
 Cmtm6
CKLF-like MARVEL transmembrane domain containing 6
chr3_+_32436151 0.398 ENSMUST00000029201.7
 Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr1_-_24612700 0.383 ENSMUST00000088336.1
 Gm10222
predicted gene 10222
chr3_-_146495115 0.375 ENSMUST00000093951.2
 Spata1
spermatogenesis associated 1
chr18_-_6241486 0.360 ENSMUST00000025083.7
 Kif5b
kinesin family member 5B
chr18_-_73754457 0.309 ENSMUST00000041138.2
 Elac1
elaC homolog 1 (E. coli)
chr17_-_78684262 0.308 ENSMUST00000145480.1
 Strn
striatin, calmodulin binding protein
chr9_+_54538984 0.306 ENSMUST00000060242.5
ENSMUST00000118413.1
 Sh2d7

SH2 domain containing 7

chr12_+_69963452 0.299 ENSMUST00000110560.1
 Gm3086
predicted gene 3086
chr11_-_110095937 0.291 ENSMUST00000106664.3
ENSMUST00000046223.7
ENSMUST00000106662.1
 Abca8a


ATP-binding cassette, sub-family A (ABC1), member 8a


chr4_+_58943575 0.287 ENSMUST00000107554.1
 Zkscan16
zinc finger with KRAB and SCAN domains 16
chr17_-_24936894 0.279 ENSMUST00000115228.2
ENSMUST00000117509.1
ENSMUST00000121723.1
ENSMUST00000119115.1
ENSMUST00000121787.1
ENSMUST00000088345.5
ENSMUST00000120035.1
 Mapk8ip3






mitogen-activated protein kinase 8 interacting protein 3






chrX_+_153237466 0.273 ENSMUST00000143880.1
 Klf8
Kruppel-like factor 8
chr7_+_140941550 0.258 ENSMUST00000079403.4
 Athl1
ATH1, acid trehalase-like 1 (yeast)
chr6_-_136941887 0.245 ENSMUST00000111891.1
 Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr9_-_42457594 0.245 ENSMUST00000125995.1
 Tbcel
tubulin folding cofactor E-like
chr17_-_24936969 0.243 ENSMUST00000178969.1
ENSMUST00000115229.3
 Mapk8ip3

mitogen-activated protein kinase 8 interacting protein 3

chr11_-_110095974 0.241 ENSMUST00000100287.2
 Abca8a
ATP-binding cassette, sub-family A (ABC1), member 8a
chr1_+_150392794 0.238 ENSMUST00000124973.2
 Tpr
translocated promoter region
chr15_+_100334929 0.238 ENSMUST00000075420.4
 Mettl7a3
methyltransferase like 7A3
chr2_-_176144697 0.214 ENSMUST00000178872.1
 Gm2004
predicted gene 2004
chr1_+_155158703 0.204 ENSMUST00000027743.7
 Stx6
syntaxin 6
chr3_+_95282897 0.200 ENSMUST00000039537.7
ENSMUST00000107187.2
 Fam63a

family with sequence similarity 63, member A

chr12_+_4769278 0.199 ENSMUST00000020967.4
 Pfn4
profilin family, member 4
chr8_-_85432841 0.193 ENSMUST00000047749.5
 4921524J17Rik
RIKEN cDNA 4921524J17 gene
chr16_-_57292845 0.188 ENSMUST00000023434.8
ENSMUST00000120112.1
ENSMUST00000119407.1
 Tmem30c


transmembrane protein 30C


chr2_+_176807362 0.178 ENSMUST00000179435.1
 Gm14295
predicted gene 14295
chr7_-_127376028 0.148 ENSMUST00000067425.4
 Zfp747
zinc finger protein 747
chr11_-_98018308 0.148 ENSMUST00000107561.2
 Cacnb1
calcium channel, voltage-dependent, beta 1 subunit
chr17_+_29274078 0.144 ENSMUST00000149405.2
 BC004004
cDNA sequence BC004004
chr15_+_83563571 0.139 ENSMUST00000047419.6
 Tspo
translocator protein
chr7_+_102223021 0.135 ENSMUST00000156529.1
ENSMUST00000138479.1
ENSMUST00000126914.1
ENSMUST00000033292.7
ENSMUST00000146559.1
 Pgap2




post-GPI attachment to proteins 2




chr2_+_177009681 0.132 ENSMUST00000178182.1
 Gm14419
predicted gene 14419
chr17_+_36837123 0.124 ENSMUST00000179968.1
ENSMUST00000130367.1
ENSMUST00000130801.1
ENSMUST00000144182.1
ENSMUST00000123715.1
ENSMUST00000053434.8
 Trim26





tripartite motif-containing 26





chrX_+_162901226 0.123 ENSMUST00000101095.2
 Ctps2
cytidine 5'-triphosphate synthase 2
chr4_-_108071327 0.102 ENSMUST00000106701.1
 Scp2
sterol carrier protein 2, liver
chr2_+_164460945 0.102 ENSMUST00000072452.4
 Sys1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr11_+_87664274 0.077 ENSMUST00000092800.5
 Rnf43
ring finger protein 43
chr17_+_40561498 0.072 ENSMUST00000167713.1
ENSMUST00000097324.3
 Gm5494
Gm5494
predicted gene 5494
predicted gene 5494
chr15_+_99006056 0.068 ENSMUST00000079818.3
 Gm8973
predicted gene 8973
chr5_+_86804214 0.048 ENSMUST00000119339.1
ENSMUST00000120498.1
 Ythdc1

YTH domain containing 1

chr2_-_165388245 0.047 ENSMUST00000103084.3
 Zfp334
zinc finger protein 334
chr11_-_107348130 0.030 ENSMUST00000134763.1
 Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chr11_+_5520652 0.027 ENSMUST00000063084.9
 Xbp1
X-box binding protein 1
chr6_-_136941694 0.023 ENSMUST00000032344.5
 Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr2_-_175133322 0.015 ENSMUST00000099029.3
 Gm14399
predicted gene 14399
chr15_-_58847321 0.004 ENSMUST00000075109.5
 Ube2d4
ubiquitin-conjugating enzyme E2D 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.9 GO:0000255 allantoin metabolic process(GO:0000255)
0.4 1.2 GO:0050883 regulation of sulfur amino acid metabolic process(GO:0031335) musculoskeletal movement, spinal reflex action(GO:0050883)
0.3 0.9 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.3 1.4 GO:0015671 oxygen transport(GO:0015671)
0.2 2.5 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 3.6 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.2 0.8 GO:0035617 stress granule disassembly(GO:0035617) plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386) regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.7 GO:1902995 apolipoprotein A-I-mediated signaling pathway(GO:0038027) regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995) positive regulation of apoptotic cell clearance(GO:2000427)
0.1 0.6 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.6 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.1 0.2 GO:0032240 RNA import into nucleus(GO:0006404) mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.1 0.8 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 2.1 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1 0.3 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.3 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.0 1.0 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 1.0 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.1 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.0 1.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.9 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.1 GO:0032382 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373)
0.0 0.1 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.9 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.1 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.2 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 1.1 GO:0046323 glucose import(GO:0046323)
0.0 0.5 GO:0007257 activation of JUN kinase activity(GO:0007257)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 2.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.9 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 3.6 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.2 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.8 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.6 GO:0031143 pseudopodium(GO:0031143)
0.0 1.0 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 1.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.7 GO:0001891 phagocytic cup(GO:0001891)
0.0 1.0 GO:0034707 chloride channel complex(GO:0034707)
0.0 2.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 2.1 GO:0042641 actomyosin(GO:0042641)
0.0 0.5 GO:0030673 axolemma(GO:0030673)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.9 GO:0005905 clathrin-coated pit(GO:0005905)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0004096 catalase activity(GO:0004096)
0.2 0.7 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.2 0.6 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.1 0.8 GO:0099609 microtubule lateral binding(GO:0099609)
0.1 0.9 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 1.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 2.9 GO:0017046 peptide hormone binding(GO:0017046)
0.1 1.1 GO:0005536 glucose binding(GO:0005536)
0.1 1.0 GO:0050811 GABA-A receptor activity(GO:0004890) GABA receptor binding(GO:0050811)
0.1 0.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.6 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 2.5 GO:0030507 spectrin binding(GO:0030507)
0.0 0.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.5 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.0 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0050632 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
0.0 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.2 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.3 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID_IL5_PATHWAY IL5-mediated signaling events
0.0 2.9 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 0.5 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 2.1 PID_CDC42_PATHWAY CDC42 signaling events
0.0 0.8 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 0.6 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.3 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.9 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.1 1.1 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 2.5 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 0.9 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.5 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.9 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.7 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.8 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.6 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.2 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.2 REACTOME_REGULATION_OF_INSULIN_SECRETION Genes involved in Regulation of Insulin Secretion