Motif ID: Arid5b

Z-value: 0.238


Transcription factors associated with Arid5b:

Gene SymbolEntrez IDGene Name
Arid5b ENSMUSG00000019947.9 Arid5b

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Arid5bmm10_v2_chr10_-_68278713_68278735-0.028.6e-01Click!


Activity profile for motif Arid5b.

activity profile for motif Arid5b


Sorted Z-values histogram for motif Arid5b

Sorted Z-values for motif Arid5b



Network of associatons between targets according to the STRING database.



First level regulatory network of Arid5b

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_115908644 0.630 ENSMUST00000141101.1
 Cit
citron
chr12_-_91746020 0.544 ENSMUST00000166967.1
 Ston2
stonin 2
chr4_+_105157339 0.542 ENSMUST00000064139.7
 Ppap2b
phosphatidic acid phosphatase type 2B
chr3_+_34649987 0.505 ENSMUST00000099151.2
 Sox2
SRY-box containing gene 2
chr12_-_10900296 0.457 ENSMUST00000085735.2
 Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chr10_-_6980376 0.441 ENSMUST00000105617.1
 Ipcef1
interaction protein for cytohesin exchange factors 1
chr14_-_47394253 0.435 ENSMUST00000177822.1
 Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr3_-_95882031 0.380 ENSMUST00000161994.1
 Gm129
predicted gene 129
chr4_+_132638987 0.369 ENSMUST00000135299.1
ENSMUST00000081726.6
ENSMUST00000180250.1
ENSMUST00000020197.7
ENSMUST00000079157.4
 Eya3




eyes absent 3 homolog (Drosophila)




chr2_+_25180737 0.347 ENSMUST00000104999.2
 Nrarp
Notch-regulated ankyrin repeat protein
chr9_+_87022014 0.336 ENSMUST00000168529.2
ENSMUST00000174724.1
ENSMUST00000173126.1
 Cyb5r4


cytochrome b5 reductase 4


chr15_-_13173607 0.321 ENSMUST00000036439.4
 Cdh6
cadherin 6
chr1_+_180568913 0.315 ENSMUST00000027777.6
 Parp1
poly (ADP-ribose) polymerase family, member 1
chr1_+_88227005 0.315 ENSMUST00000061013.6
ENSMUST00000113130.1
 Mroh2a

maestro heat-like repeat family member 2A

chr13_+_23533869 0.315 ENSMUST00000073261.2
 Hist1h2af
histone cluster 1, H2af
chr9_+_21196705 0.311 ENSMUST00000003395.9
 Pde4a
phosphodiesterase 4A, cAMP specific
chr3_-_19264959 0.297 ENSMUST00000121951.1
 Pde7a
phosphodiesterase 7A
chr3_-_95882193 0.296 ENSMUST00000159863.1
ENSMUST00000159739.1
ENSMUST00000036418.3
 Gm129


predicted gene 129


chr6_+_120666388 0.284 ENSMUST00000112686.1
 Cecr2
cat eye syndrome chromosome region, candidate 2
chr15_-_55548164 0.273 ENSMUST00000165356.1
 Mrpl13
mitochondrial ribosomal protein L13
chr15_-_44428303 0.264 ENSMUST00000038719.6
 Nudcd1
NudC domain containing 1
chr5_-_31697598 0.248 ENSMUST00000031018.7
 Rbks
ribokinase
chr4_-_129662442 0.242 ENSMUST00000003828.4
 Kpna6
karyopherin (importin) alpha 6
chr10_+_94576254 0.215 ENSMUST00000117929.1
 Tmcc3
transmembrane and coiled coil domains 3
chrX_+_140456613 0.207 ENSMUST00000033809.3
 Prps1
phosphoribosyl pyrophosphate synthetase 1
chr4_-_75278246 0.202 ENSMUST00000030103.8
 Tmem261
transmembrane protein 261
chr13_+_21735055 0.196 ENSMUST00000087714.4
 Hist1h4j
histone cluster 1, H4j
chr18_-_15063560 0.195 ENSMUST00000168989.1
 Kctd1
potassium channel tetramerisation domain containing 1
chr1_+_180330470 0.193 ENSMUST00000070181.6
 Itpkb
inositol 1,4,5-trisphosphate 3-kinase B
chr10_-_109010955 0.191 ENSMUST00000105276.1
ENSMUST00000064054.7
 Syt1

synaptotagmin I

chr9_-_45984816 0.188 ENSMUST00000172450.1
 Pafah1b2
platelet-activating factor acetylhydrolase, isoform 1b, subunit 2
chr16_+_32431225 0.187 ENSMUST00000115140.1
 Pcyt1a
phosphate cytidylyltransferase 1, choline, alpha isoform
chr9_+_112227443 0.186 ENSMUST00000161216.1
 2310075C17Rik
RIKEN cDNA 2310075C17 gene
chr18_+_62662108 0.170 ENSMUST00000163259.1
 Gm17732
predicted gene, 17732
chr8_-_79399513 0.170 ENSMUST00000066091.7
ENSMUST00000109885.1
ENSMUST00000066081.3
 Smad1


SMAD family member 1


chrX_-_157492280 0.157 ENSMUST00000112529.1
 Sms
spermine synthase
chr9_-_106789130 0.152 ENSMUST00000046502.5
 Rad54l2
RAD54 like 2 (S. cerevisiae)
chr12_+_110601439 0.148 ENSMUST00000018851.7
 Dync1h1
dynein cytoplasmic 1 heavy chain 1
chr15_+_37233036 0.133 ENSMUST00000161405.1
ENSMUST00000022895.8
ENSMUST00000161532.1
 Grhl2


grainyhead-like 2 (Drosophila)


chr12_-_24680890 0.130 ENSMUST00000156453.2
 Cys1
cystin 1
chr8_-_119840522 0.130 ENSMUST00000168698.1
ENSMUST00000034285.6
 Cotl1

coactosin-like 1 (Dictyostelium)

chr3_-_95882232 0.120 ENSMUST00000161866.1
 Gm129
predicted gene 129
chr3_-_89998656 0.111 ENSMUST00000079724.4
 Hax1
HCLS1 associated X-1
chrM_+_8600 0.098 ENSMUST00000082409.1
 mt-Co3
mitochondrially encoded cytochrome c oxidase III
chr2_-_84678828 0.093 ENSMUST00000111665.1
 Tmx2
thioredoxin-related transmembrane protein 2
chr10_+_127420867 0.092 ENSMUST00000064793.6
 R3hdm2
R3H domain containing 2
chr4_-_150909428 0.080 ENSMUST00000128075.1
ENSMUST00000105674.1
ENSMUST00000105673.1
 Park7


Parkinson disease (autosomal recessive, early onset) 7


chr9_+_122117338 0.078 ENSMUST00000120173.1
ENSMUST00000134949.1
ENSMUST00000119215.1
 Snrk


SNF related kinase


chr12_+_108792946 0.070 ENSMUST00000021692.7
 Yy1
YY1 transcription factor
chr2_-_151744142 0.069 ENSMUST00000109869.1
 Psmf1
proteasome (prosome, macropain) inhibitor subunit 1
chr11_+_108682602 0.066 ENSMUST00000106718.3
ENSMUST00000106715.1
ENSMUST00000106724.3
 Cep112


centrosomal protein 112


chrX_-_101222426 0.058 ENSMUST00000120389.1
ENSMUST00000156473.1
ENSMUST00000077876.3
 Snx12


sorting nexin 12


chr4_+_122836236 0.047 ENSMUST00000030412.4
ENSMUST00000121870.1
ENSMUST00000097902.4
 Ppt1


palmitoyl-protein thioesterase 1


chr10_+_14523062 0.043 ENSMUST00000096020.5
 Gm10335
predicted gene 10335
chr7_-_101921186 0.042 ENSMUST00000106965.1
ENSMUST00000106968.1
ENSMUST00000106967.1
 Lrrc51


leucine rich repeat containing 51


chr14_-_52213379 0.040 ENSMUST00000140603.1
 Chd8
chromodomain helicase DNA binding protein 8
chr6_+_133105239 0.039 ENSMUST00000100864.4
 2700089E24Rik
RIKEN cDNA 2700089E24 gene
chr3_+_95588990 0.030 ENSMUST00000177399.1
 Golph3l
golgi phosphoprotein 3-like
chr5_+_31494736 0.029 ENSMUST00000076949.6
ENSMUST00000117700.1
 Gpn1

GPN-loop GTPase 1

chr7_-_67645195 0.025 ENSMUST00000032775.5
ENSMUST00000053950.2
 Lrrc28

leucine rich repeat containing 28

chr10_+_116143881 0.018 ENSMUST00000105271.2
 Ptprr
protein tyrosine phosphatase, receptor type, R
chr2_+_76650264 0.013 ENSMUST00000099986.2
 Dfnb59
deafness, autosomal recessive 59 (human)
chr3_-_19265007 0.011 ENSMUST00000091314.4
 Pde7a
phosphodiesterase 7A
chr9_-_42461414 0.010 ENSMUST00000066179.7
 Tbcel
tubulin folding cofactor E-like
chr10_-_14718191 0.003 ENSMUST00000020016.4
 Gje1
gap junction protein, epsilon 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.1 0.5 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 0.2 GO:0046101 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.1 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.2 GO:0006014 D-ribose metabolic process(GO:0006014)
0.1 0.2 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.1 GO:0072382 minus-end-directed vesicle transport along microtubule(GO:0072382)
0.0 0.2 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
0.0 0.4 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.3 GO:0001842 neural fold formation(GO:0001842)
0.0 0.3 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.6 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:0050787 glycolate metabolic process(GO:0009441) enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) glycolate biosynthetic process(GO:0046295) detoxification of mercury ion(GO:0050787) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of cellular amino acid biosynthetic process(GO:2000284)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.0 0.1 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.2 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0090537 CERF complex(GO:0090537)
0.1 0.2 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.4 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.2 GO:0031045 dense core granule(GO:0031045)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.1 0.3 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 0.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.3 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.5 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0036470 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.0 0.2 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 0.1 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.0 0.2 PID_ALK2_PATHWAY ALK2 signaling events
0.0 0.3 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.4 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.4 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 0.6 PID_RHOA_PATHWAY RhoA signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.5 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis