Motif ID: Arnt
Z-value: 0.615
Transcription factors associated with Arnt:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Arnt | ENSMUSG00000015522.12 | Arnt |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Arnt | mm10_v2_chr3_+_95434386_95434428 | -0.21 | 1.3e-01 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 116 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.4 | 7.3 | GO:0021557 | oculomotor nerve development(GO:0021557) |
| 0.1 | 6.5 | GO:0006284 | base-excision repair(GO:0006284) |
| 0.0 | 6.3 | GO:0030177 | positive regulation of Wnt signaling pathway(GO:0030177) |
| 0.6 | 6.1 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
| 0.4 | 4.6 | GO:0002087 | regulation of respiratory gaseous exchange by neurological system process(GO:0002087) |
| 0.3 | 4.2 | GO:0097154 | GABAergic neuron differentiation(GO:0097154) |
| 0.2 | 3.9 | GO:0071392 | cellular response to estradiol stimulus(GO:0071392) |
| 1.0 | 3.0 | GO:0032696 | negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899) |
| 0.1 | 2.9 | GO:0001913 | T cell mediated cytotoxicity(GO:0001913) |
| 0.5 | 2.8 | GO:2000969 | positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969) |
| 0.9 | 2.7 | GO:0021759 | globus pallidus development(GO:0021759) |
| 0.1 | 2.5 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.8 | 2.4 | GO:1904170 | regulation of bleb assembly(GO:1904170) |
| 0.8 | 2.4 | GO:0060010 | Sertoli cell fate commitment(GO:0060010) |
| 0.1 | 2.4 | GO:0009649 | entrainment of circadian clock(GO:0009649) |
| 0.1 | 2.3 | GO:0015804 | neutral amino acid transport(GO:0015804) |
| 0.5 | 2.0 | GO:0035606 | peptidyl-cysteine S-trans-nitrosylation(GO:0035606) |
| 0.6 | 1.9 | GO:2000642 | negative regulation of early endosome to late endosome transport(GO:2000642) |
| 0.2 | 1.8 | GO:1902416 | positive regulation of mRNA binding(GO:1902416) |
| 0.5 | 1.6 | GO:0045819 | plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 58 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 6.5 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 0.2 | 6.3 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.1 | 5.4 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.6 | 3.9 | GO:0001740 | Barr body(GO:0001740) |
| 0.3 | 3.8 | GO:1990907 | beta-catenin-TCF complex(GO:1990907) |
| 0.7 | 2.9 | GO:0089717 | spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717) |
| 0.8 | 2.5 | GO:0033186 | CAF-1 complex(GO:0033186) |
| 0.5 | 2.4 | GO:0005826 | actomyosin contractile ring(GO:0005826) |
| 0.3 | 2.0 | GO:0097452 | GAIT complex(GO:0097452) |
| 0.1 | 1.8 | GO:0045120 | pronucleus(GO:0045120) |
| 0.0 | 1.8 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.2 | 1.7 | GO:0032009 | early phagosome(GO:0032009) |
| 0.0 | 1.6 | GO:0000784 | nuclear chromosome, telomeric region(GO:0000784) |
| 0.0 | 1.4 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.4 | 1.3 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
| 0.3 | 1.2 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 0.1 | 1.2 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.2 | 1.1 | GO:0010009 | cytoplasmic side of endosome membrane(GO:0010009) |
| 0.1 | 1.1 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.0 | 1.1 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 92 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 7.3 | GO:0008432 | JUN kinase binding(GO:0008432) |
| 0.6 | 6.5 | GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity(GO:0051575) |
| 1.1 | 6.4 | GO:0043426 | MRF binding(GO:0043426) |
| 1.1 | 5.7 | GO:0001640 | adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) |
| 0.1 | 4.0 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.1 | 3.7 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
| 0.0 | 3.1 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.5 | 3.0 | GO:0030284 | estrogen receptor activity(GO:0030284) |
| 0.4 | 2.9 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
| 0.2 | 2.7 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) |
| 0.3 | 2.5 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
| 0.2 | 2.4 | GO:0035014 | phosphatidylinositol 3-kinase regulator activity(GO:0035014) |
| 0.7 | 2.0 | GO:0035605 | peptidyl-cysteine S-nitrosylase activity(GO:0035605) |
| 0.2 | 1.8 | GO:1990715 | mRNA CDS binding(GO:1990715) |
| 0.1 | 1.8 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
| 0.0 | 1.7 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
| 0.5 | 1.6 | GO:0000402 | open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402) |
| 0.3 | 1.6 | GO:0017108 | 5'-flap endonuclease activity(GO:0017108) |
| 0.1 | 1.6 | GO:0010314 | phosphatidylinositol-5-phosphate binding(GO:0010314) |
| 0.0 | 1.6 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
Gene overrepresentation in C2:CP category:
Showing 1 to 19 of 19 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 7.3 | PID_DELTA_NP63_PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.1 | 6.9 | PID_CMYB_PATHWAY | C-MYB transcription factor network |
| 0.1 | 6.8 | PID_IL4_2PATHWAY | IL4-mediated signaling events |
| 0.1 | 6.2 | PID_HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.1 | 2.7 | PID_HNF3B_PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 2.6 | PID_MYC_ACTIV_PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.0 | 1.8 | PID_RXR_VDR_PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.0 | 1.8 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 1.6 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
| 0.1 | 1.4 | PID_S1P_META_PATHWAY | Sphingosine 1-phosphate (S1P) pathway |
| 0.1 | 1.3 | SA_G2_AND_M_PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.0 | 1.3 | PID_THROMBIN_PAR1_PATHWAY | PAR1-mediated thrombin signaling events |
| 0.0 | 0.9 | PID_BETA_CATENIN_NUC_PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.0 | 0.6 | PID_BMP_PATHWAY | BMP receptor signaling |
| 0.0 | 0.6 | PID_REG_GR_PATHWAY | Glucocorticoid receptor regulatory network |
| 0.0 | 0.5 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 0.4 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 0.4 | PID_WNT_CANONICAL_PATHWAY | Canonical Wnt signaling pathway |
| 0.0 | 0.1 | PID_IL8_CXCR1_PATHWAY | IL8- and CXCR1-mediated signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 39 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 6.7 | REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT | Genes involved in Regulation of beta-cell development |
| 0.8 | 6.5 | REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 0.0 | 6.2 | REACTOME_MRNA_SPLICING | Genes involved in mRNA Splicing |
| 0.3 | 6.1 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.1 | 5.7 | REACTOME_GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.0 | 5.7 | REACTOME_SIGNALING_BY_RHO_GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.1 | 3.9 | REACTOME_PACKAGING_OF_TELOMERE_ENDS | Genes involved in Packaging Of Telomere Ends |
| 0.1 | 3.7 | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.1 | 2.9 | REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.0 | 2.1 | REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S | Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S |
| 0.1 | 1.8 | REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.1 | 1.8 | REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |
| 0.2 | 1.6 | REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND | Genes involved in Removal of the Flap Intermediate from the C-strand |
| 0.1 | 1.6 | REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 0.0 | 1.4 | REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.0 | 1.4 | REACTOME_PEPTIDE_CHAIN_ELONGATION | Genes involved in Peptide chain elongation |
| 0.0 | 1.4 | REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.0 | 1.4 | REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS | Genes involved in Class A/1 (Rhodopsin-like receptors) |
| 0.1 | 1.3 | REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.0 | 1.2 | REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
