Motif ID: Ascl2

Z-value: 0.569


Transcription factors associated with Ascl2:

Gene SymbolEntrez IDGene Name
Ascl2 ENSMUSG00000009248.5 Ascl2



Activity profile for motif Ascl2.

activity profile for motif Ascl2


Sorted Z-values histogram for motif Ascl2

Sorted Z-values for motif Ascl2



Network of associatons between targets according to the STRING database.



First level regulatory network of Ascl2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_106458440 3.763 ENSMUST00000086795.6
Barhl2
BarH-like 2 (Drosophila)
chr7_-_28302238 3.669 ENSMUST00000108315.3
Dll3
delta-like 3 (Drosophila)
chr15_-_78773452 3.132 ENSMUST00000018313.5
Mfng
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr8_+_31091593 2.590 ENSMUST00000161713.1
Dusp26
dual specificity phosphatase 26 (putative)
chr11_+_99864476 2.239 ENSMUST00000092694.3
Gm11559
predicted gene 11559
chr7_+_45216671 2.143 ENSMUST00000134420.1
Tead2
TEA domain family member 2
chr6_+_56017489 2.098 ENSMUST00000052827.4
Ppp1r17
protein phosphatase 1, regulatory subunit 17
chr7_-_141443314 2.000 ENSMUST00000106005.2
Lrdd
leucine-rich and death domain containing
chr8_+_105518736 1.917 ENSMUST00000034363.5
Hsd11b2
hydroxysteroid 11-beta dehydrogenase 2
chr5_+_149411749 1.833 ENSMUST00000093110.5
Medag
mesenteric estrogen dependent adipogenesis
chr7_+_142471838 1.693 ENSMUST00000038946.2
Lsp1
lymphocyte specific 1
chr6_-_56362356 1.671 ENSMUST00000044505.7
ENSMUST00000166102.1
ENSMUST00000164037.1
ENSMUST00000114327.2
Pde1c



phosphodiesterase 1C



chr6_+_105677745 1.630 ENSMUST00000113261.2
ENSMUST00000113264.2
Cntn4

contactin 4

chr2_+_136052180 1.493 ENSMUST00000144403.1
Lamp5
lysosomal-associated membrane protein family, member 5
chr5_+_114568016 1.457 ENSMUST00000043650.7
Fam222a
family with sequence similarity 222, member A
chr6_-_72235559 1.456 ENSMUST00000042646.7
Atoh8
atonal homolog 8 (Drosophila)
chr8_-_122699066 1.453 ENSMUST00000127984.1
Cbfa2t3
core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
chr8_-_105471481 1.440 ENSMUST00000014990.6
Tppp3
tubulin polymerization-promoting protein family member 3
chr7_+_142472080 1.438 ENSMUST00000105966.1
Lsp1
lymphocyte specific 1
chr4_+_11156411 1.402 ENSMUST00000029865.3
Trp53inp1
transformation related protein 53 inducible nuclear protein 1
chr11_-_114795888 1.370 ENSMUST00000000206.3
Btbd17
BTB (POZ) domain containing 17
chr11_+_117849223 1.351 ENSMUST00000081387.4
Birc5
baculoviral IAP repeat-containing 5
chr2_-_172940299 1.300 ENSMUST00000009143.7
Bmp7
bone morphogenetic protein 7
chr2_-_170406501 1.291 ENSMUST00000154650.1
Bcas1
breast carcinoma amplified sequence 1
chr3_-_17786834 1.263 ENSMUST00000099198.2
Gm10742
predicted gene 10742
chr6_+_14901344 1.261 ENSMUST00000115477.1
Foxp2
forkhead box P2
chr9_-_43239816 1.247 ENSMUST00000034512.5
Oaf
OAF homolog (Drosophila)
chr9_-_96437434 1.219 ENSMUST00000070500.2
BC043934
cDNA sequence BC043934
chrX_-_106485214 1.211 ENSMUST00000039447.7
Fndc3c1
fibronectin type III domain containing 3C1
chr8_+_94977101 1.208 ENSMUST00000179619.1
Gpr56
G protein-coupled receptor 56
chr10_+_80494835 1.200 ENSMUST00000051773.8
Onecut3
one cut domain, family member 3
chr19_-_16873830 1.173 ENSMUST00000072915.2
Foxb2
forkhead box B2
chr10_-_92162753 1.135 ENSMUST00000182197.1
Rmst
rhabdomyosarcoma 2 associated transcript (non-coding RNA)
chr9_+_74848437 1.132 ENSMUST00000161862.1
ENSMUST00000162089.1
ENSMUST00000160017.1
ENSMUST00000160950.1
Gm16551


Gm20649
predicted gene 16551


predicted gene 20649
chr7_+_100227638 1.107 ENSMUST00000054436.8
Pgm2l1
phosphoglucomutase 2-like 1
chr9_-_57836706 1.097 ENSMUST00000164010.1
ENSMUST00000171444.1
ENSMUST00000098686.3
Arid3b


AT rich interactive domain 3B (BRIGHT-like)


chr5_-_69341699 1.088 ENSMUST00000054095.4
Kctd8
potassium channel tetramerisation domain containing 8
chr19_+_25610533 1.084 ENSMUST00000048935.4
Dmrt3
doublesex and mab-3 related transcription factor 3
chr1_-_84696182 1.074 ENSMUST00000049126.6
Dner
delta/notch-like EGF-related receptor
chr12_-_40037387 1.069 ENSMUST00000146905.1
Arl4a
ADP-ribosylation factor-like 4A
chr6_+_4755327 1.066 ENSMUST00000176551.1
Peg10
paternally expressed 10
chr13_+_51846673 1.034 ENSMUST00000021903.2
Gadd45g
growth arrest and DNA-damage-inducible 45 gamma
chr3_-_33143227 1.005 ENSMUST00000108219.1
Pex5l
peroxisomal biogenesis factor 5-like
chr15_+_4375462 1.002 ENSMUST00000061925.4
Plcxd3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr3_-_116253467 0.989 ENSMUST00000090473.5
Gpr88
G-protein coupled receptor 88
chr15_+_34238026 0.984 ENSMUST00000022867.3
Laptm4b
lysosomal-associated protein transmembrane 4B
chr17_-_35027909 0.983 ENSMUST00000040151.2
Sapcd1
suppressor APC domain containing 1
chr12_-_40038025 0.981 ENSMUST00000101472.3
Arl4a
ADP-ribosylation factor-like 4A
chr12_+_17690793 0.979 ENSMUST00000071858.3
Hpcal1
hippocalcin-like 1
chr11_-_68927049 0.964 ENSMUST00000038932.7
Odf4
outer dense fiber of sperm tails 4
chr6_-_39206782 0.963 ENSMUST00000002305.8
Jhdm1d
jumonji C domain-containing histone demethylase 1 homolog D (S. cerevisiae)
chr10_+_94514825 0.961 ENSMUST00000065060.5
Tmcc3
transmembrane and coiled coil domains 3
chr1_+_72824482 0.954 ENSMUST00000047328.4
Igfbp2
insulin-like growth factor binding protein 2
chr8_+_70863127 0.952 ENSMUST00000050921.2
A230052G05Rik
RIKEN cDNA A230052G05 gene
chr5_+_137641334 0.950 ENSMUST00000177466.1
ENSMUST00000166099.2
Sap25

sin3 associated polypeptide

chr12_+_53248677 0.949 ENSMUST00000101432.2
Npas3
neuronal PAS domain protein 3
chr11_+_117849286 0.936 ENSMUST00000093906.4
Birc5
baculoviral IAP repeat-containing 5
chr13_+_24638636 0.932 ENSMUST00000110384.2
ENSMUST00000058009.9
ENSMUST00000038477.6
Fam65b


family with sequence similarity 65, member B


chr1_+_153665274 0.903 ENSMUST00000152114.1
ENSMUST00000111812.1
Rgs8

regulator of G-protein signaling 8

chr9_+_57998036 0.891 ENSMUST00000181289.1
Gm17322
predicted gene, 17322
chr15_-_84855093 0.889 ENSMUST00000016768.5
Phf21b
PHD finger protein 21B
chr9_-_62537036 0.880 ENSMUST00000048043.5
Coro2b
coronin, actin binding protein, 2B
chr19_-_45560508 0.863 ENSMUST00000026239.6
Poll
polymerase (DNA directed), lambda
chrX_+_109095359 0.858 ENSMUST00000033598.8
Sh3bgrl
SH3-binding domain glutamic acid-rich protein like
chrX_-_106485367 0.843 ENSMUST00000140707.1
Fndc3c1
fibronectin type III domain containing 3C1
chr7_+_16875302 0.832 ENSMUST00000108493.1
Dact3
dapper homolog 3, antagonist of beta-catenin (xenopus)
chr19_+_5068077 0.800 ENSMUST00000070630.6
Cd248
CD248 antigen, endosialin
chrX_-_133688978 0.800 ENSMUST00000149154.1
ENSMUST00000167944.1
Pcdh19

protocadherin 19

chr10_+_69212634 0.797 ENSMUST00000020101.5
Rhobtb1
Rho-related BTB domain containing 1
chr15_-_102004305 0.762 ENSMUST00000023952.8
Krt8
keratin 8
chr4_+_94556546 0.761 ENSMUST00000094969.1
Gm10306
predicted gene 10306
chrX_-_16911774 0.758 ENSMUST00000040134.7
Ndp
Norrie disease (pseudoglioma) (human)
chr4_-_43523595 0.755 ENSMUST00000107914.3
Tpm2
tropomyosin 2, beta
chr7_+_142460834 0.744 ENSMUST00000018963.4
ENSMUST00000105967.1
Lsp1

lymphocyte specific 1

chr9_-_58201705 0.735 ENSMUST00000163200.1
ENSMUST00000165276.1
Islr2

immunoglobulin superfamily containing leucine-rich repeat 2

chr17_-_35702297 0.707 ENSMUST00000135078.1
Ddr1
discoidin domain receptor family, member 1
chrX_-_122397351 0.701 ENSMUST00000079490.4
Nap1l3
nucleosome assembly protein 1-like 3
chr9_-_39604124 0.699 ENSMUST00000042485.4
ENSMUST00000141370.1
AW551984

expressed sequence AW551984

chr4_-_133263042 0.698 ENSMUST00000105908.3
ENSMUST00000030674.7
Sytl1

synaptotagmin-like 1

chr10_+_67979709 0.693 ENSMUST00000117086.1
Rtkn2
rhotekin 2
chr1_-_183147461 0.683 ENSMUST00000171366.1
Disp1
dispatched homolog 1 (Drosophila)
chr13_-_47043116 0.681 ENSMUST00000110118.1
ENSMUST00000124948.1
ENSMUST00000021806.3
ENSMUST00000136864.1
Tpmt



thiopurine methyltransferase



chr5_-_66618772 0.668 ENSMUST00000162994.1
ENSMUST00000159512.1
ENSMUST00000159786.1
Apbb2


amyloid beta (A4) precursor protein-binding, family B, member 2


chrX_+_143518576 0.667 ENSMUST00000033640.7
Pak3
p21 protein (Cdc42/Rac)-activated kinase 3
chr13_-_98891036 0.663 ENSMUST00000109399.2
Tnpo1
transportin 1
chr3_+_123446913 0.653 ENSMUST00000029603.8
Prss12
protease, serine, 12 neurotrypsin (motopsin)
chr17_+_56303321 0.647 ENSMUST00000001258.8
Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
chr12_-_17176888 0.646 ENSMUST00000170580.1
Kcnf1
potassium voltage-gated channel, subfamily F, member 1
chr4_-_91399984 0.645 ENSMUST00000102799.3
Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr2_+_34772089 0.644 ENSMUST00000028222.6
ENSMUST00000100171.2
Hspa5

heat shock protein 5

chr7_+_142460809 0.636 ENSMUST00000105968.1
Lsp1
lymphocyte specific 1
chr4_+_33031371 0.628 ENSMUST00000124992.1
Ube2j1
ubiquitin-conjugating enzyme E2J 1
chr17_+_56303396 0.623 ENSMUST00000113038.1
Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
chr13_-_119408985 0.609 ENSMUST00000099149.3
ENSMUST00000069902.6
ENSMUST00000109204.1
Nnt


nicotinamide nucleotide transhydrogenase


chr9_-_67760208 0.605 ENSMUST00000068526.5
M5C1000I18Rik
RIKEN cDNA M5C1000I18 gene
chr1_+_153665627 0.595 ENSMUST00000147482.1
Rgs8
regulator of G-protein signaling 8
chr11_+_69965396 0.594 ENSMUST00000018713.6
Cldn7
claudin 7
chr5_-_98030727 0.592 ENSMUST00000031281.9
Antxr2
anthrax toxin receptor 2
chr11_-_46312220 0.591 ENSMUST00000129474.1
ENSMUST00000093166.4
ENSMUST00000165599.2
Cyfip2


cytoplasmic FMR1 interacting protein 2


chr1_+_153665587 0.590 ENSMUST00000147700.1
Rgs8
regulator of G-protein signaling 8
chr1_+_129273344 0.578 ENSMUST00000073527.6
ENSMUST00000040311.7
Thsd7b

thrombospondin, type I, domain containing 7B

chr18_-_10610124 0.573 ENSMUST00000097670.3
Esco1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr10_+_78780470 0.569 ENSMUST00000005490.8
Slc1a6
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
chr14_+_34673888 0.568 ENSMUST00000048263.7
Wapal
wings apart-like homolog (Drosophila)
chr2_-_92370999 0.567 ENSMUST00000176810.1
ENSMUST00000090582.4
Gyltl1b

glycosyltransferase-like 1B

chr11_-_4118778 0.549 ENSMUST00000003681.7
Sec14l2
SEC14-like 2 (S. cerevisiae)
chr18_-_61707583 0.543 ENSMUST00000025472.1
Pcyox1l
prenylcysteine oxidase 1 like
chr3_+_16183177 0.539 ENSMUST00000108345.2
ENSMUST00000108346.2
Ythdf3

YTH domain family 3

chr4_+_43957678 0.539 ENSMUST00000107855.1
Glipr2
GLI pathogenesis-related 2
chr1_-_182019927 0.536 ENSMUST00000078719.6
ENSMUST00000111030.3
ENSMUST00000177811.1
ENSMUST00000111024.3
ENSMUST00000111025.2
Enah




enabled homolog (Drosophila)




chr10_+_17796256 0.536 ENSMUST00000037964.6
Txlnb
taxilin beta
chr4_-_43523746 0.533 ENSMUST00000150592.1
Tpm2
tropomyosin 2, beta
chr11_-_100822525 0.533 ENSMUST00000107358.2
Stat5b
signal transducer and activator of transcription 5B
chr2_+_35282380 0.529 ENSMUST00000028239.6
Gsn
gelsolin
chr4_+_33031527 0.528 ENSMUST00000029944.6
Ube2j1
ubiquitin-conjugating enzyme E2J 1
chr11_-_79146407 0.525 ENSMUST00000018478.4
ENSMUST00000108264.1
Ksr1

kinase suppressor of ras 1

chr2_-_17731035 0.524 ENSMUST00000028080.5
Nebl
nebulette
chr4_-_35845204 0.519 ENSMUST00000164772.1
ENSMUST00000065173.2
Lingo2

leucine rich repeat and Ig domain containing 2

chr11_-_79059872 0.519 ENSMUST00000141409.1
Ksr1
kinase suppressor of ras 1
chr1_-_125912160 0.517 ENSMUST00000159417.1
Lypd1
Ly6/Plaur domain containing 1
chr4_-_43523388 0.517 ENSMUST00000107913.3
ENSMUST00000030184.5
Tpm2

tropomyosin 2, beta

chrX_+_36795642 0.513 ENSMUST00000016463.3
Slc25a5
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5
chr15_+_101412402 0.513 ENSMUST00000068904.8
Krt7
keratin 7
chr5_+_135725713 0.510 ENSMUST00000127096.1
Por
P450 (cytochrome) oxidoreductase
chr12_+_79130777 0.508 ENSMUST00000021550.6
Arg2
arginase type II
chr16_-_16869255 0.505 ENSMUST00000075017.4
Vpreb1
pre-B lymphocyte gene 1
chr3_+_121426495 0.503 ENSMUST00000029773.8
Cnn3
calponin 3, acidic
chr19_-_60581013 0.493 ENSMUST00000111460.3
ENSMUST00000081790.7
ENSMUST00000166712.1
Cacul1


CDK2 associated, cullin domain 1


chr10_+_26822560 0.492 ENSMUST00000135866.1
Arhgap18
Rho GTPase activating protein 18
chrX_+_101449078 0.490 ENSMUST00000033674.5
Itgb1bp2
integrin beta 1 binding protein 2
chr18_-_88927447 0.485 ENSMUST00000147313.1
Socs6
suppressor of cytokine signaling 6
chr4_+_43957401 0.482 ENSMUST00000030202.7
Glipr2
GLI pathogenesis-related 2
chr13_-_98926374 0.476 ENSMUST00000109401.1
Tnpo1
transportin 1
chr3_-_110250963 0.473 ENSMUST00000106567.1
Prmt6
protein arginine N-methyltransferase 6
chr1_-_91413163 0.469 ENSMUST00000086851.1
Hes6
hairy and enhancer of split 6
chr18_-_10610048 0.468 ENSMUST00000115864.1
Esco1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr1_-_164458345 0.465 ENSMUST00000027863.7
Atp1b1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr5_-_28210022 0.464 ENSMUST00000118882.1
Cnpy1
canopy 1 homolog (zebrafish)
chr8_+_62951195 0.462 ENSMUST00000118003.1
Spock3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3
chr6_-_12749193 0.460 ENSMUST00000046121.6
ENSMUST00000172356.1
Thsd7a

thrombospondin, type I, domain containing 7A

chrX_-_100626568 0.460 ENSMUST00000015812.5
Pdzd11
PDZ domain containing 11
chr9_-_22052021 0.458 ENSMUST00000003501.7
Elavl3
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)
chr17_+_84511832 0.458 ENSMUST00000047206.5
Plekhh2
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr2_+_33216051 0.446 ENSMUST00000004208.5
Angptl2
angiopoietin-like 2
chr5_+_136967859 0.441 ENSMUST00000001790.5
Cldn15
claudin 15
chr8_-_41374602 0.436 ENSMUST00000110417.1
ENSMUST00000034000.8
ENSMUST00000143057.1
Asah1


N-acylsphingosine amidohydrolase 1


chr16_+_21794320 0.435 ENSMUST00000181780.1
ENSMUST00000181960.1
1300002E11Rik

RIKEN cDNA 1300002E11 gene

chr5_+_150673739 0.435 ENSMUST00000016569.4
ENSMUST00000038900.8
Pds5b

PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)

chr16_+_18348181 0.432 ENSMUST00000115614.2
ENSMUST00000115613.1
ENSMUST00000090103.3
Arvcf


armadillo repeat gene deleted in velo-cardio-facial syndrome


chr2_+_5845243 0.432 ENSMUST00000127116.1
Nudt5
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr17_-_35704000 0.427 ENSMUST00000097333.3
ENSMUST00000003628.6
Ddr1

discoidin domain receptor family, member 1

chr7_+_16944645 0.424 ENSMUST00000094807.5
Pnmal2
PNMA-like 2
chr19_+_45560569 0.421 ENSMUST00000047057.7
Dpcd
deleted in primary ciliary dyskinesia
chr17_-_21845759 0.420 ENSMUST00000084141.4
Zfp820
zinc finger protein 820
chr9_-_62510498 0.420 ENSMUST00000164246.2
Coro2b
coronin, actin binding protein, 2B
chr18_-_53744509 0.417 ENSMUST00000049811.6
Cep120
centrosomal protein 120
chr2_+_167538192 0.411 ENSMUST00000052631.7
Snai1
snail homolog 1 (Drosophila)
chr1_-_172590463 0.410 ENSMUST00000065679.6
Slamf8
SLAM family member 8
chr1_+_171419027 0.403 ENSMUST00000171362.1
Tstd1
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
chr2_-_92371039 0.402 ENSMUST00000068586.6
Gyltl1b
glycosyltransferase-like 1B
chr4_+_62583568 0.399 ENSMUST00000098031.3
Rgs3
regulator of G-protein signaling 3
chr2_-_10048580 0.395 ENSMUST00000026888.4
Taf3
TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chrX_-_13846508 0.394 ENSMUST00000115436.2
ENSMUST00000033321.4
ENSMUST00000115438.3
Cask


calcium/calmodulin-dependent serine protein kinase (MAGUK family)


chr4_-_133967235 0.394 ENSMUST00000123234.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr6_-_77979515 0.392 ENSMUST00000159626.1
ENSMUST00000075340.5
ENSMUST00000162273.1
Ctnna2


catenin (cadherin associated protein), alpha 2


chr18_-_10181792 0.392 ENSMUST00000067947.5
Rock1
Rho-associated coiled-coil containing protein kinase 1
chr4_+_45184815 0.390 ENSMUST00000134280.1
ENSMUST00000044773.5
Frmpd1

FERM and PDZ domain containing 1

chr5_-_66618752 0.383 ENSMUST00000162366.1
Apbb2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr5_-_66618636 0.381 ENSMUST00000162382.1
ENSMUST00000160870.1
ENSMUST00000087256.5
ENSMUST00000160103.1
ENSMUST00000162349.1
Apbb2




amyloid beta (A4) precursor protein-binding, family B, member 2




chr3_-_67515487 0.381 ENSMUST00000178314.1
ENSMUST00000054825.4
Rarres1

retinoic acid receptor responder (tazarotene induced) 1

chr19_+_45018114 0.381 ENSMUST00000178087.1
Lzts2
leucine zipper, putative tumor suppressor 2
chr11_+_99041237 0.380 ENSMUST00000017637.6
Igfbp4
insulin-like growth factor binding protein 4
chr4_-_155010984 0.380 ENSMUST00000105631.2
ENSMUST00000139976.2
ENSMUST00000145662.2
Plch2


phospholipase C, eta 2


chr17_-_35697971 0.371 ENSMUST00000146472.1
Ddr1
discoidin domain receptor family, member 1
chr12_+_73286779 0.369 ENSMUST00000140523.1
Slc38a6
solute carrier family 38, member 6
chr3_+_107895821 0.365 ENSMUST00000004134.4
Gstm5
glutathione S-transferase, mu 5
chr7_+_127800844 0.363 ENSMUST00000106271.1
ENSMUST00000138432.1
Hsd3b7

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7

chr13_-_107890059 0.360 ENSMUST00000105097.2
Zswim6
zinc finger SWIM-type containing 6
chr10_+_57486354 0.358 ENSMUST00000079833.4
Hsf2
heat shock factor 2
chr4_-_135272798 0.355 ENSMUST00000037099.8
Clic4
chloride intracellular channel 4 (mitochondrial)
chr9_-_71592265 0.351 ENSMUST00000169573.1
ENSMUST00000166843.1
ENSMUST00000163998.1
Myzap
Gcom1

myocardial zonula adherens protein
GRINL1A complex locus

chr7_-_61982290 0.350 ENSMUST00000180481.1
A330076H08Rik
RIKEN cDNA A330076H08 gene
chr6_+_48647224 0.348 ENSMUST00000078223.3
Gimap8
GTPase, IMAP family member 8
chr12_+_73286868 0.344 ENSMUST00000153941.1
ENSMUST00000122920.1
ENSMUST00000101313.3
Slc38a6


solute carrier family 38, member 6


chr9_+_85842852 0.339 ENSMUST00000098500.3
Tpbg
trophoblast glycoprotein
chr13_-_98206151 0.338 ENSMUST00000109426.1
Arhgef28
Rho guanine nucleotide exchange factor (GEF) 28
chr8_+_95352258 0.337 ENSMUST00000034243.5
Mmp15
matrix metallopeptidase 15
chr3_-_108210438 0.336 ENSMUST00000117784.1
ENSMUST00000119650.1
ENSMUST00000117409.1
Atxn7l2


ataxin 7-like 2


chr4_-_141933080 0.335 ENSMUST00000036701.7
Fhad1
forkhead-associated (FHA) phosphopeptide binding domain 1
chr6_+_3993776 0.335 ENSMUST00000031673.5
Gngt1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr6_-_77979652 0.330 ENSMUST00000161846.1
ENSMUST00000160894.1
Ctnna2

catenin (cadherin associated protein), alpha 2

chr15_-_63997969 0.326 ENSMUST00000164532.1
Fam49b
family with sequence similarity 49, member B
chr8_-_4217261 0.326 ENSMUST00000168386.2
BC068157
cDNA sequence BC068157
chr17_+_87282880 0.324 ENSMUST00000041110.5
ENSMUST00000125875.1
Ttc7

tetratricopeptide repeat domain 7

chr5_+_12383156 0.323 ENSMUST00000030868.6
Sema3d
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chr16_+_36828364 0.318 ENSMUST00000114819.1
ENSMUST00000023535.3
Iqcb1

IQ calmodulin-binding motif containing 1

chr3_+_75557530 0.318 ENSMUST00000161776.1
ENSMUST00000029423.8
Serpini1

serine (or cysteine) peptidase inhibitor, clade I, member 1

chr2_+_121449362 0.318 ENSMUST00000110615.1
ENSMUST00000099475.5
Serf2

small EDRK-rich factor 2

chr11_-_82871133 0.316 ENSMUST00000071152.7
ENSMUST00000108173.3
Rffl

ring finger and FYVE like domain containing protein

chr17_-_35703971 0.311 ENSMUST00000148065.1
Ddr1
discoidin domain receptor family, member 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.7 3.7 GO:0007386 compartment pattern specification(GO:0007386)
0.5 1.4 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.4 1.3 GO:0072076 hyaluranon cable assembly(GO:0036118) nephrogenic mesenchyme development(GO:0072076) negative regulation of glomerular mesangial cell proliferation(GO:0072125) negative regulation of glomerulus development(GO:0090194) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.3 3.1 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.3 2.3 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.2 0.7 GO:0046544 development of secondary male sexual characteristics(GO:0046544)
0.2 1.0 GO:0061743 motor learning(GO:0061743)
0.2 0.6 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.2 1.0 GO:0034421 post-translational protein acetylation(GO:0034421)
0.2 1.5 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.2 0.8 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.2 0.2 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.2 0.5 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.2 0.7 GO:0019323 D-ribose metabolic process(GO:0006014) pentose catabolic process(GO:0019323)
0.2 0.5 GO:1903903 striated muscle atrophy(GO:0014891) positive regulation of keratinocyte apoptotic process(GO:1902174) regulation of establishment of T cell polarity(GO:1903903)
0.2 1.0 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.2 0.7 GO:0035754 B cell chemotaxis(GO:0035754)
0.2 1.9 GO:0001977 renal system process involved in regulation of blood volume(GO:0001977)
0.2 0.5 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.2 0.8 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 2.1 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1 0.9 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.1 1.0 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1 0.4 GO:2000508 regulation of dendritic cell chemotaxis(GO:2000508)
0.1 0.5 GO:0046210 nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.1 0.5 GO:0090467 regulation of amino acid import(GO:0010958) L-arginine import(GO:0043091) arginine import(GO:0090467)
0.1 0.5 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1 0.7 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.1 1.2 GO:1904153 tumor necrosis factor biosynthetic process(GO:0042533) regulation of tumor necrosis factor biosynthetic process(GO:0042534) negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 1.4 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 0.8 GO:0070458 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.1 1.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.4 GO:0010957 negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1 2.4 GO:0048368 lateral mesoderm development(GO:0048368)
0.1 0.3 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 1.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 1.3 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 1.5 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 1.0 GO:0042095 interferon-gamma biosynthetic process(GO:0042095)
0.1 0.3 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.1 0.3 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 3.8 GO:0001709 cell fate determination(GO:0001709)
0.1 0.3 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.1 1.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.5 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 1.3 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
0.1 0.6 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 0.3 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.1 0.2 GO:0009814 defense response, incompatible interaction(GO:0009814)
0.1 0.6 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 1.6 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 0.2 GO:0090289 regulation of osteoclast proliferation(GO:0090289)
0.1 0.3 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.4 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 0.5 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.1 0.7 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.1 1.1 GO:0007220 Notch receptor processing(GO:0007220)
0.1 0.6 GO:0089718 amino acid import across plasma membrane(GO:0089718) L-glutamate import across plasma membrane(GO:0098712)
0.1 0.2 GO:0021586 pons maturation(GO:0021586)
0.1 0.2 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.1 0.5 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1 0.2 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.1 0.3 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 0.1 GO:0042713 sperm ejaculation(GO:0042713)
0.1 0.7 GO:0060539 diaphragm development(GO:0060539)
0.1 0.8 GO:0060033 anatomical structure regression(GO:0060033)
0.1 1.0 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.1 0.2 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 0.2 GO:0002586 regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002580) positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.1 0.5 GO:0090205 positive regulation of cholesterol biosynthetic process(GO:0045542) positive regulation of cholesterol metabolic process(GO:0090205)
0.1 0.2 GO:0040009 regulation of growth rate(GO:0040009)
0.1 0.1 GO:0019062 virion attachment to host cell(GO:0019062) adhesion of symbiont to host cell(GO:0044650)
0.1 0.2 GO:0042359 vitamin D metabolic process(GO:0042359)
0.1 0.3 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 0.1 GO:0048389 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023) intermediate mesoderm development(GO:0048389) pattern specification involved in mesonephros development(GO:0061227) anterior/posterior pattern specification involved in kidney development(GO:0072098)
0.1 0.1 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0 1.8 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.3 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.9 GO:0042711 maternal behavior(GO:0042711)
0.0 0.5 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.3 GO:0034773 histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.0 0.3 GO:0002634 regulation of germinal center formation(GO:0002634)
0.0 0.4 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.0 0.4 GO:0021678 third ventricle development(GO:0021678)
0.0 0.4 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.0 0.4 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.3 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.2 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.4 GO:0009650 UV protection(GO:0009650)
0.0 0.1 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.0 0.6 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.0 0.6 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 0.1 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.0 0.3 GO:0070228 regulation of lymphocyte apoptotic process(GO:0070228) T cell apoptotic process(GO:0070231) regulation of T cell apoptotic process(GO:0070232)
0.0 0.2 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.1 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 1.5 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.5 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.1 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.0 0.6 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.4 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.0 0.2 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.1 GO:0032298 positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
0.0 0.2 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.1 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 0.3 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.3 GO:0007602 phototransduction(GO:0007602)
0.0 0.6 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.1 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 0.1 GO:0070944 neutrophil mediated killing of bacterium(GO:0070944)
0.0 0.6 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0 0.2 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.1 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.3 GO:0001916 positive regulation of T cell mediated cytotoxicity(GO:0001916)
0.0 0.1 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.0 0.3 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.0 0.1 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0015791 polyol transport(GO:0015791)
0.0 0.1 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.1 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.4 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.1 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
0.0 0.2 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.1 GO:0010046 arginine biosynthetic process(GO:0006526) response to mycotoxin(GO:0010046)
0.0 0.8 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.0 0.2 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 1.8 GO:0010921 regulation of phosphatase activity(GO:0010921)
0.0 0.2 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 1.4 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.1 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.0 0.9 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.2 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.6 GO:1901998 toxin transport(GO:1901998)
0.0 0.2 GO:0042407 cristae formation(GO:0042407)
0.0 0.1 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.2 GO:0051984 positive regulation of chromosome segregation(GO:0051984)
0.0 0.5 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.0 0.2 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.2 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0 0.3 GO:0045103 intermediate filament-based process(GO:0045103)
0.0 0.3 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:2000370 positive regulation of clathrin-mediated endocytosis(GO:2000370)
0.0 0.2 GO:0042098 T cell proliferation(GO:0042098)
0.0 0.2 GO:0042755 eating behavior(GO:0042755)
0.0 0.1 GO:0033327 Leydig cell differentiation(GO:0033327)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.5 2.3 GO:0032133 interphase microtubule organizing center(GO:0031021) chromosome passenger complex(GO:0032133)
0.3 1.0 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.2 1.5 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.2 2.8 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.2 1.4 GO:0097427 microtubule bundle(GO:0097427)
0.1 1.0 GO:0001520 outer dense fiber(GO:0001520)
0.1 0.5 GO:0071817 MMXD complex(GO:0071817)
0.1 0.5 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.1 0.3 GO:0031983 vesicle lumen(GO:0031983)
0.1 0.5 GO:0097452 GAIT complex(GO:0097452)
0.1 1.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.5 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 0.2 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.1 0.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 3.1 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 0.2 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 0.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.5 GO:0030478 actin cap(GO:0030478)
0.1 0.2 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.1 0.8 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 0.3 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.1 0.3 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.2 GO:0061702 inflammasome complex(GO:0061702)
0.0 0.2 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.7 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.2 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.7 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.4 GO:0005652 nuclear lamina(GO:0005652)
0.0 1.3 GO:0000791 euchromatin(GO:0000791)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.3 GO:0097542 ciliary tip(GO:0097542)
0.0 0.3 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.1 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 2.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.4 GO:0005776 autophagosome(GO:0005776)
0.0 0.2 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0032420 stereocilium(GO:0032420)
0.0 0.4 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.4 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.3 GO:0031941 filamentous actin(GO:0031941)
0.0 0.8 GO:0030864 cortical actin cytoskeleton(GO:0030864)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.9 2.6 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.3 1.3 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.3 2.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 0.7 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.2 1.7 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 1.8 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.2 1.8 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.2 1.0 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.2 2.6 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0033764)
0.2 1.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 1.5 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.7 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 0.5 GO:0016708 nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726)
0.1 4.3 GO:0005112 Notch binding(GO:0005112)
0.1 2.1 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.1 0.4 GO:0004096 aminoacylase activity(GO:0004046) catalase activity(GO:0004096)
0.1 0.3 GO:0016015 morphogen activity(GO:0016015)
0.1 0.3 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 0.3 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.3 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.1 0.5 GO:0044020 protein-arginine omega-N monomethyltransferase activity(GO:0035241) histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.1 0.3 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.1 0.9 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 0.5 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 3.7 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 0.3 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.1 0.4 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.2 GO:0001729 ceramide kinase activity(GO:0001729)
0.1 0.5 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 0.7 GO:0015197 peptide transporter activity(GO:0015197)
0.1 2.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.3 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 1.0 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 1.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.8 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1 0.3 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.1 0.5 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.4 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.1 0.3 GO:0023029 MHC class Ib protein binding(GO:0023029)
0.1 0.5 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.5 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.2 GO:2001069 glycogen binding(GO:2001069)
0.0 0.5 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.5 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 0.6 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.4 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.2 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.5 GO:0005522 profilin binding(GO:0005522)
0.0 1.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.3 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.3 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 1.4 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 1.5 GO:0070888 E-box binding(GO:0070888)
0.0 1.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.8 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.6 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.6 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.1 GO:0035877 death effector domain binding(GO:0035877)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.3 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 1.0 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.1 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.0 1.3 GO:0016209 antioxidant activity(GO:0016209)
0.0 0.2 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.1 GO:0002135 CTP binding(GO:0002135)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 7.3 GO:0003779 actin binding(GO:0003779)
0.0 0.3 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.3 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.2 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 1.0 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 6.6 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.0 0.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.6 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 1.0 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 0.5 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.0 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.2 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.2 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.2 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.2 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.3 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 1.0 GO:0003774 motor activity(GO:0003774)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 PID_ALK2_PATHWAY ALK2 signaling events
0.1 4.3 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 2.3 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 1.9 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 4.2 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 0.6 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.0 0.4 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 1.0 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 2.0 PID_ERBB4_PATHWAY ErbB4 signaling events
0.0 0.3 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 0.4 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.4 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.1 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.5 PID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.8 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.3 PID_TNF_PATHWAY TNF receptor signaling pathway
0.0 0.3 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.5 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.4 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 0.1 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 1.0 PID_ERBB1_DOWNSTREAM_PATHWAY ErbB1 downstream signaling
0.0 1.6 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.5 ST_GA13_PATHWAY G alpha 13 Pathway
0.0 0.2 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.4 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 0.3 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.2 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.0 0.1 PID_IL27_PATHWAY IL27-mediated signaling events
0.0 0.1 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.1 2.0 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.6 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.4 REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1 0.2 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 0.6 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 0.3 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 0.6 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.1 0.7 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1 1.7 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.5 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.3 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.8 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.4 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.0 0.3 REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.7 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES Genes involved in Generation of second messenger molecules
0.0 1.1 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 1.0 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.3 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.1 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.6 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.4 REACTOME_PHASE_II_CONJUGATION Genes involved in Phase II conjugation
0.0 0.6 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.1 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.2 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.5 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.0 2.5 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.3 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.2 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.5 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.1 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.6 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.2 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.3 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.5 REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.1 REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.1 REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.3 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.6 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.0 0.1 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones