Motif ID: Atf6
Z-value: 1.343
Transcription factors associated with Atf6:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Atf6 | ENSMUSG00000026663.6 | Atf6 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Atf6 | mm10_v2_chr1_-_170867761_170867784 | -0.02 | 8.8e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.0 | 15.0 | GO:0043379 | memory T cell differentiation(GO:0043379) negative regulation of isotype switching to IgE isotypes(GO:0048294) |
| 2.3 | 13.7 | GO:0060075 | regulation of resting membrane potential(GO:0060075) |
| 2.2 | 8.8 | GO:0099566 | regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566) |
| 2.0 | 6.1 | GO:0010360 | negative regulation of anion channel activity(GO:0010360) |
| 1.8 | 10.7 | GO:0019695 | choline metabolic process(GO:0019695) |
| 1.8 | 8.9 | GO:1900748 | positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) |
| 1.4 | 4.1 | GO:1902630 | regulation of membrane hyperpolarization(GO:1902630) |
| 1.3 | 4.0 | GO:0070343 | white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350) |
| 1.2 | 16.8 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
| 1.2 | 4.7 | GO:0035609 | C-terminal protein deglutamylation(GO:0035609) |
| 1.1 | 4.3 | GO:0072531 | pyrimidine-containing compound transmembrane transport(GO:0072531) |
| 1.0 | 8.1 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 1.0 | 3.0 | GO:0015747 | urate transport(GO:0015747) |
| 1.0 | 8.8 | GO:0090166 | Golgi disassembly(GO:0090166) |
| 0.9 | 3.7 | GO:0045113 | regulation of integrin biosynthetic process(GO:0045113) |
| 0.9 | 8.1 | GO:0036371 | protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) |
| 0.9 | 4.4 | GO:0021993 | initiation of neural tube closure(GO:0021993) |
| 0.8 | 3.3 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
| 0.8 | 7.1 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.8 | 2.4 | GO:0034035 | sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) |
| 0.7 | 2.2 | GO:0035523 | protein K29-linked deubiquitination(GO:0035523) |
| 0.7 | 13.4 | GO:0035641 | locomotory exploration behavior(GO:0035641) |
| 0.7 | 4.2 | GO:0010881 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion(GO:0010881) |
| 0.7 | 2.0 | GO:0009298 | GDP-mannose biosynthetic process(GO:0009298) |
| 0.7 | 3.4 | GO:1901843 | positive regulation of high voltage-gated calcium channel activity(GO:1901843) |
| 0.7 | 16.0 | GO:0002091 | negative regulation of receptor internalization(GO:0002091) |
| 0.7 | 2.0 | GO:2000331 | regulation of terminal button organization(GO:2000331) |
| 0.7 | 5.3 | GO:2000301 | negative regulation of synaptic vesicle exocytosis(GO:2000301) |
| 0.6 | 5.8 | GO:0071569 | protein ufmylation(GO:0071569) |
| 0.6 | 12.0 | GO:0002115 | store-operated calcium entry(GO:0002115) |
| 0.6 | 1.9 | GO:0070375 | ERK5 cascade(GO:0070375) |
| 0.6 | 2.5 | GO:0071638 | negative regulation of monocyte chemotactic protein-1 production(GO:0071638) |
| 0.6 | 7.2 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
| 0.6 | 4.8 | GO:1902474 | positive regulation of protein localization to synapse(GO:1902474) |
| 0.6 | 1.7 | GO:0003195 | tricuspid valve formation(GO:0003195) right ventricular cardiac muscle tissue morphogenesis(GO:0003221) |
| 0.6 | 1.7 | GO:0060478 | acrosomal vesicle exocytosis(GO:0060478) |
| 0.5 | 4.3 | GO:0099550 | trans-synaptic signalling, modulating synaptic transmission(GO:0099550) |
| 0.5 | 1.6 | GO:1902219 | negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219) |
| 0.5 | 1.5 | GO:0090204 | protein localization to nuclear pore(GO:0090204) |
| 0.5 | 3.4 | GO:1990573 | potassium ion import across plasma membrane(GO:1990573) |
| 0.4 | 2.7 | GO:0009405 | pathogenesis(GO:0009405) |
| 0.4 | 10.6 | GO:0090036 | regulation of protein kinase C signaling(GO:0090036) |
| 0.4 | 2.8 | GO:1990416 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) postsynaptic density organization(GO:0097106) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416) |
| 0.4 | 11.3 | GO:0043496 | regulation of protein homodimerization activity(GO:0043496) |
| 0.4 | 5.0 | GO:0045176 | apical protein localization(GO:0045176) |
| 0.4 | 3.7 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
| 0.4 | 0.4 | GO:0009826 | unidimensional cell growth(GO:0009826) |
| 0.4 | 2.1 | GO:0032811 | negative regulation of epinephrine secretion(GO:0032811) |
| 0.4 | 1.1 | GO:0060265 | positive regulation of respiratory burst involved in inflammatory response(GO:0060265) |
| 0.3 | 1.0 | GO:0042726 | flavin-containing compound metabolic process(GO:0042726) |
| 0.3 | 1.3 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
| 0.3 | 1.9 | GO:2000672 | negative regulation of motor neuron apoptotic process(GO:2000672) |
| 0.3 | 1.5 | GO:1902031 | regulation of NADP metabolic process(GO:1902031) |
| 0.3 | 3.9 | GO:0044144 | regulation of growth of symbiont in host(GO:0044126) modulation of growth of symbiont involved in interaction with host(GO:0044144) |
| 0.3 | 2.3 | GO:0098712 | L-glutamate import across plasma membrane(GO:0098712) |
| 0.3 | 2.0 | GO:0006102 | isocitrate metabolic process(GO:0006102) |
| 0.3 | 4.8 | GO:0007252 | I-kappaB phosphorylation(GO:0007252) |
| 0.3 | 1.4 | GO:0031642 | negative regulation of myelination(GO:0031642) cellular response to cold(GO:0070417) |
| 0.3 | 1.4 | GO:1900170 | negative regulation of glucocorticoid mediated signaling pathway(GO:1900170) |
| 0.3 | 4.4 | GO:0032808 | lacrimal gland development(GO:0032808) |
| 0.3 | 1.7 | GO:0002904 | positive regulation of B cell apoptotic process(GO:0002904) |
| 0.3 | 1.1 | GO:2001245 | negative regulation of phospholipid biosynthetic process(GO:0071072) regulation of phosphatidylcholine biosynthetic process(GO:2001245) |
| 0.3 | 3.2 | GO:0043084 | penile erection(GO:0043084) |
| 0.3 | 1.8 | GO:0016480 | negative regulation of transcription from RNA polymerase III promoter(GO:0016480) |
| 0.2 | 2.0 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 0.2 | 0.7 | GO:0071492 | cellular response to UV-A(GO:0071492) |
| 0.2 | 1.2 | GO:0006689 | ganglioside catabolic process(GO:0006689) |
| 0.2 | 2.7 | GO:2000310 | regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310) |
| 0.2 | 1.4 | GO:0016093 | polyprenol metabolic process(GO:0016093) |
| 0.2 | 0.9 | GO:1901678 | iron coordination entity transport(GO:1901678) |
| 0.2 | 0.9 | GO:0044828 | negative regulation by host of viral genome replication(GO:0044828) |
| 0.2 | 1.0 | GO:1904781 | positive regulation of protein localization to centrosome(GO:1904781) |
| 0.2 | 1.2 | GO:0035873 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879) |
| 0.2 | 1.6 | GO:0097369 | sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
| 0.2 | 11.2 | GO:0001881 | receptor recycling(GO:0001881) |
| 0.2 | 3.8 | GO:0006828 | manganese ion transport(GO:0006828) |
| 0.2 | 0.7 | GO:0006824 | cobalt ion transport(GO:0006824) |
| 0.2 | 1.7 | GO:0048680 | positive regulation of axon regeneration(GO:0048680) |
| 0.2 | 6.9 | GO:0007094 | mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173) |
| 0.2 | 0.9 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 0.2 | 2.0 | GO:0060628 | regulation of ER to Golgi vesicle-mediated transport(GO:0060628) |
| 0.2 | 0.5 | GO:0032474 | otolith morphogenesis(GO:0032474) |
| 0.2 | 3.0 | GO:0007289 | spermatid nucleus differentiation(GO:0007289) |
| 0.2 | 2.5 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
| 0.2 | 6.2 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
| 0.2 | 1.5 | GO:0006620 | posttranslational protein targeting to membrane(GO:0006620) |
| 0.2 | 2.2 | GO:0006613 | cotranslational protein targeting to membrane(GO:0006613) |
| 0.2 | 0.8 | GO:0000393 | spliceosomal conformational changes to generate catalytic conformation(GO:0000393) |
| 0.1 | 6.0 | GO:0061098 | positive regulation of protein tyrosine kinase activity(GO:0061098) |
| 0.1 | 0.6 | GO:1904451 | regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453) |
| 0.1 | 2.2 | GO:0042659 | regulation of cell fate specification(GO:0042659) |
| 0.1 | 1.5 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
| 0.1 | 3.2 | GO:0070536 | protein K63-linked deubiquitination(GO:0070536) |
| 0.1 | 1.2 | GO:1990253 | cellular response to leucine starvation(GO:1990253) |
| 0.1 | 1.7 | GO:0043982 | histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982) |
| 0.1 | 1.2 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
| 0.1 | 0.9 | GO:0021886 | female meiosis I(GO:0007144) hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888) |
| 0.1 | 0.4 | GO:2001013 | cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013) |
| 0.1 | 0.4 | GO:0003199 | endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) positive regulation of monocyte chemotactic protein-1 production(GO:0071639) regulation of oxidative phosphorylation uncoupler activity(GO:2000275) cell proliferation involved in heart valve development(GO:2000793) |
| 0.1 | 5.1 | GO:0006506 | GPI anchor biosynthetic process(GO:0006506) |
| 0.1 | 0.6 | GO:0045347 | negative regulation of MHC class II biosynthetic process(GO:0045347) |
| 0.1 | 0.4 | GO:0048162 | preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162) |
| 0.1 | 2.2 | GO:0071378 | growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378) |
| 0.1 | 0.6 | GO:0060770 | negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) |
| 0.1 | 2.9 | GO:0015991 | ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662) |
| 0.1 | 0.3 | GO:0043686 | co-translational protein modification(GO:0043686) |
| 0.1 | 0.1 | GO:1902527 | positive regulation of protein monoubiquitination(GO:1902527) |
| 0.1 | 0.4 | GO:0060416 | response to growth hormone(GO:0060416) |
| 0.1 | 0.2 | GO:0002248 | connective tissue replacement involved in inflammatory response wound healing(GO:0002248) |
| 0.1 | 1.4 | GO:0008272 | sulfate transport(GO:0008272) |
| 0.1 | 0.9 | GO:0030539 | male genitalia development(GO:0030539) |
| 0.1 | 0.5 | GO:0034162 | toll-like receptor 9 signaling pathway(GO:0034162) |
| 0.1 | 2.0 | GO:0043552 | positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552) |
| 0.1 | 1.0 | GO:0000712 | resolution of meiotic recombination intermediates(GO:0000712) |
| 0.1 | 2.3 | GO:0035025 | positive regulation of Rho protein signal transduction(GO:0035025) |
| 0.1 | 1.2 | GO:2000696 | regulation of epithelial cell differentiation involved in kidney development(GO:2000696) |
| 0.1 | 0.6 | GO:0032510 | endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510) |
| 0.1 | 0.3 | GO:0010756 | positive regulation of plasminogen activation(GO:0010756) |
| 0.1 | 4.3 | GO:0015914 | phospholipid transport(GO:0015914) |
| 0.1 | 2.6 | GO:0032292 | myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292) |
| 0.1 | 1.5 | GO:0007614 | short-term memory(GO:0007614) |
| 0.1 | 3.0 | GO:0071300 | cellular response to retinoic acid(GO:0071300) |
| 0.1 | 1.4 | GO:0046325 | negative regulation of glucose import(GO:0046325) |
| 0.1 | 3.5 | GO:0060612 | adipose tissue development(GO:0060612) |
| 0.1 | 1.0 | GO:0050774 | negative regulation of dendrite morphogenesis(GO:0050774) |
| 0.1 | 0.7 | GO:0007202 | activation of phospholipase C activity(GO:0007202) positive regulation of phospholipase C activity(GO:0010863) |
| 0.1 | 0.3 | GO:0070863 | positive regulation of protein exit from endoplasmic reticulum(GO:0070863) |
| 0.1 | 1.2 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.1 | 0.1 | GO:0072076 | luteinizing hormone secretion(GO:0032275) nephrogenic mesenchyme development(GO:0072076) |
| 0.1 | 1.1 | GO:0080182 | histone H3-K4 trimethylation(GO:0080182) |
| 0.1 | 0.6 | GO:1901409 | positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
| 0.1 | 0.4 | GO:1903025 | regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025) |
| 0.1 | 2.0 | GO:0051703 | social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703) |
| 0.1 | 4.1 | GO:0070936 | protein K48-linked ubiquitination(GO:0070936) |
| 0.1 | 0.8 | GO:0014898 | muscle hypertrophy in response to stress(GO:0003299) cardiac muscle hypertrophy in response to stress(GO:0014898) |
| 0.1 | 2.0 | GO:0070830 | bicellular tight junction assembly(GO:0070830) |
| 0.1 | 0.7 | GO:0002369 | T cell cytokine production(GO:0002369) |
| 0.1 | 8.6 | GO:0071805 | potassium ion transmembrane transport(GO:0071805) |
| 0.1 | 0.5 | GO:0015074 | DNA integration(GO:0015074) |
| 0.1 | 3.1 | GO:0046626 | regulation of insulin receptor signaling pathway(GO:0046626) |
| 0.1 | 5.3 | GO:0031929 | TOR signaling(GO:0031929) |
| 0.1 | 0.3 | GO:0061034 | olfactory bulb mitral cell layer development(GO:0061034) |
| 0.1 | 0.4 | GO:0030578 | PML body organization(GO:0030578) |
| 0.1 | 4.1 | GO:0030433 | ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) |
| 0.1 | 1.0 | GO:0071577 | zinc II ion transmembrane transport(GO:0071577) |
| 0.1 | 1.2 | GO:0010758 | regulation of macrophage chemotaxis(GO:0010758) |
| 0.0 | 1.3 | GO:0001829 | trophectodermal cell differentiation(GO:0001829) |
| 0.0 | 0.2 | GO:0002553 | histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553) Golgi reassembly(GO:0090168) |
| 0.0 | 9.1 | GO:0043547 | positive regulation of GTPase activity(GO:0043547) |
| 0.0 | 0.4 | GO:0061635 | regulation of protein complex stability(GO:0061635) |
| 0.0 | 1.1 | GO:0043153 | entrainment of circadian clock by photoperiod(GO:0043153) |
| 0.0 | 1.6 | GO:0043666 | regulation of phosphoprotein phosphatase activity(GO:0043666) |
| 0.0 | 0.8 | GO:0070534 | protein K63-linked ubiquitination(GO:0070534) |
| 0.0 | 1.2 | GO:0045761 | regulation of adenylate cyclase activity(GO:0045761) |
| 0.0 | 1.2 | GO:0001702 | gastrulation with mouth forming second(GO:0001702) |
| 0.0 | 1.3 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
| 0.0 | 0.4 | GO:0061179 | negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179) |
| 0.0 | 2.1 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.0 | 0.3 | GO:0030853 | negative regulation of granulocyte differentiation(GO:0030853) |
| 0.0 | 0.5 | GO:0032411 | positive regulation of transporter activity(GO:0032411) |
| 0.0 | 0.5 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 0.0 | 1.8 | GO:0032755 | positive regulation of interleukin-6 production(GO:0032755) |
| 0.0 | 3.3 | GO:0032869 | cellular response to insulin stimulus(GO:0032869) |
| 0.0 | 3.1 | GO:1903169 | regulation of calcium ion transmembrane transport(GO:1903169) |
| 0.0 | 4.9 | GO:0061025 | membrane fusion(GO:0061025) |
| 0.0 | 0.3 | GO:0003157 | endocardium development(GO:0003157) primitive hemopoiesis(GO:0060215) |
| 0.0 | 0.7 | GO:0018279 | protein N-linked glycosylation via asparagine(GO:0018279) |
| 0.0 | 1.1 | GO:0046513 | ceramide biosynthetic process(GO:0046513) |
| 0.0 | 0.8 | GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I(GO:0002474) |
| 0.0 | 0.8 | GO:0042255 | ribosome assembly(GO:0042255) |
| 0.0 | 0.2 | GO:0030828 | positive regulation of cGMP biosynthetic process(GO:0030828) |
| 0.0 | 2.6 | GO:0016051 | carbohydrate biosynthetic process(GO:0016051) |
| 0.0 | 1.1 | GO:0006418 | tRNA aminoacylation for protein translation(GO:0006418) |
| 0.0 | 1.2 | GO:0045669 | positive regulation of osteoblast differentiation(GO:0045669) |
| 0.0 | 0.5 | GO:0048147 | negative regulation of fibroblast proliferation(GO:0048147) |
| 0.0 | 1.8 | GO:0045598 | regulation of fat cell differentiation(GO:0045598) |
| 0.0 | 1.0 | GO:0030641 | regulation of cellular pH(GO:0030641) |
| 0.0 | 0.3 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 0.0 | 2.1 | GO:0006814 | sodium ion transport(GO:0006814) |
| 0.0 | 0.7 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
| 0.0 | 1.0 | GO:0000045 | autophagosome assembly(GO:0000045) |
| 0.0 | 1.5 | GO:0007631 | feeding behavior(GO:0007631) |
| 0.0 | 1.6 | GO:0030518 | intracellular steroid hormone receptor signaling pathway(GO:0030518) |
| 0.0 | 0.2 | GO:1990403 | embryonic brain development(GO:1990403) |
| 0.0 | 2.2 | GO:0008361 | regulation of cell size(GO:0008361) |
| 0.0 | 1.0 | GO:0071774 | response to fibroblast growth factor(GO:0071774) |
| 0.0 | 0.3 | GO:0033866 | coenzyme A biosynthetic process(GO:0015937) nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033) |
| 0.0 | 0.4 | GO:2001222 | regulation of neuron migration(GO:2001222) |
| 0.0 | 1.3 | GO:0030308 | negative regulation of cell growth(GO:0030308) |
| 0.0 | 0.1 | GO:0032511 | late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511) |
| 0.0 | 0.5 | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184) |
| 0.0 | 0.4 | GO:0051091 | positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091) |
| 0.0 | 0.5 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
| 0.0 | 0.0 | GO:0032804 | negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) dibasic protein processing(GO:0090472) negative regulation of receptor catabolic process(GO:2000645) |
| 0.0 | 0.2 | GO:0003333 | amino acid transmembrane transport(GO:0003333) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.4 | 13.8 | GO:1902937 | inward rectifier potassium channel complex(GO:1902937) |
| 1.8 | 26.5 | GO:0043083 | synaptic cleft(GO:0043083) |
| 1.2 | 8.3 | GO:0005827 | polar microtubule(GO:0005827) |
| 1.1 | 16.3 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.8 | 4.0 | GO:0005784 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
| 0.6 | 1.7 | GO:0070985 | TFIIK complex(GO:0070985) |
| 0.5 | 2.6 | GO:0070044 | synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044) |
| 0.4 | 2.1 | GO:0038039 | G-protein coupled receptor heterodimeric complex(GO:0038039) |
| 0.4 | 1.6 | GO:0099569 | presynaptic cytoskeleton(GO:0099569) |
| 0.4 | 6.0 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 0.4 | 18.8 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.4 | 16.8 | GO:0043034 | costamere(GO:0043034) |
| 0.4 | 8.1 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.4 | 5.5 | GO:0044754 | autolysosome(GO:0044754) |
| 0.4 | 4.8 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.4 | 5.3 | GO:0097449 | astrocyte projection(GO:0097449) |
| 0.3 | 1.0 | GO:1990730 | VCP-NSFL1C complex(GO:1990730) |
| 0.3 | 2.9 | GO:0033179 | proton-transporting V-type ATPase, V0 domain(GO:0033179) |
| 0.2 | 1.2 | GO:1990131 | Gtr1-Gtr2 GTPase complex(GO:1990131) |
| 0.2 | 12.6 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.2 | 3.4 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.2 | 1.7 | GO:0060053 | neurofilament cytoskeleton(GO:0060053) |
| 0.2 | 1.2 | GO:0042582 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
| 0.2 | 1.5 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 0.2 | 0.9 | GO:0001652 | granular component(GO:0001652) |
| 0.2 | 11.7 | GO:0030667 | secretory granule membrane(GO:0030667) |
| 0.2 | 1.8 | GO:0001739 | sex chromatin(GO:0001739) |
| 0.2 | 2.4 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.2 | 13.2 | GO:0005657 | replication fork(GO:0005657) |
| 0.2 | 13.7 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.2 | 1.5 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
| 0.1 | 2.5 | GO:0032279 | asymmetric synapse(GO:0032279) |
| 0.1 | 0.6 | GO:0097574 | lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795) photoreceptor cell terminal bouton(GO:1990796) |
| 0.1 | 1.5 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
| 0.1 | 7.6 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.1 | 4.0 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.1 | 29.7 | GO:0030426 | growth cone(GO:0030426) |
| 0.1 | 1.0 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
| 0.1 | 4.7 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.1 | 1.7 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.1 | 1.0 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
| 0.1 | 3.0 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.1 | 0.5 | GO:0070847 | core mediator complex(GO:0070847) |
| 0.1 | 1.7 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
| 0.1 | 4.2 | GO:0034704 | calcium channel complex(GO:0034704) |
| 0.1 | 1.1 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.1 | 2.0 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.1 | 0.6 | GO:0030130 | clathrin coat of trans-Golgi network vesicle(GO:0030130) |
| 0.1 | 4.3 | GO:0030117 | membrane coat(GO:0030117) coated membrane(GO:0048475) |
| 0.1 | 2.9 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
| 0.1 | 0.6 | GO:0097542 | ciliary tip(GO:0097542) |
| 0.1 | 1.4 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
| 0.1 | 1.2 | GO:0043189 | NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562) |
| 0.1 | 0.4 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
| 0.0 | 1.6 | GO:0071339 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
| 0.0 | 0.3 | GO:0005964 | phosphorylase kinase complex(GO:0005964) |
| 0.0 | 2.9 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 11.7 | GO:0097060 | synaptic membrane(GO:0097060) |
| 0.0 | 2.0 | GO:0016459 | myosin complex(GO:0016459) |
| 0.0 | 3.1 | GO:0032587 | ruffle membrane(GO:0032587) |
| 0.0 | 0.3 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
| 0.0 | 4.6 | GO:0009986 | cell surface(GO:0009986) |
| 0.0 | 0.1 | GO:0097433 | dense body(GO:0097433) |
| 0.0 | 1.4 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.0 | 7.8 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.0 | 0.4 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
| 0.0 | 0.9 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.0 | 0.5 | GO:0030008 | TRAPP complex(GO:0030008) |
| 0.0 | 8.7 | GO:0000139 | Golgi membrane(GO:0000139) |
| 0.0 | 0.6 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 0.0 | 1.1 | GO:0005795 | Golgi stack(GO:0005795) |
| 0.0 | 2.3 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 0.0 | 1.9 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.0 | 1.7 | GO:0000123 | histone acetyltransferase complex(GO:0000123) |
| 0.0 | 1.2 | GO:0005776 | autophagosome(GO:0005776) |
| 0.0 | 0.8 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.0 | 0.6 | GO:0031902 | late endosome membrane(GO:0031902) |
| 0.0 | 0.2 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
| 0.0 | 0.3 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
| 0.0 | 1.0 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.0 | 0.4 | GO:0032420 | stereocilium(GO:0032420) |
| 0.0 | 1.1 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.0 | 1.4 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 3.0 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.0 | 1.0 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.0 | 5.1 | GO:0005874 | microtubule(GO:0005874) |
| 0.0 | 16.4 | GO:0005794 | Golgi apparatus(GO:0005794) |
| 0.0 | 1.3 | GO:0043679 | axon terminus(GO:0043679) |
| 0.0 | 0.4 | GO:0097546 | ciliary base(GO:0097546) |
| 0.0 | 0.1 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.0 | 4.7 | GO:0043025 | neuronal cell body(GO:0043025) |
| 0.0 | 0.6 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.0 | 2.3 | GO:0005773 | vacuole(GO:0005773) |
| 0.0 | 0.3 | GO:0035097 | histone methyltransferase complex(GO:0035097) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.7 | 10.7 | GO:0004104 | cholinesterase activity(GO:0004104) choline binding(GO:0033265) |
| 2.2 | 8.7 | GO:0005483 | soluble NSF attachment protein activity(GO:0005483) |
| 1.9 | 5.6 | GO:0004698 | calcium-dependent protein kinase C activity(GO:0004698) |
| 1.8 | 7.1 | GO:0047275 | glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275) |
| 1.5 | 8.8 | GO:0099583 | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) |
| 1.3 | 5.3 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
| 1.3 | 15.0 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) |
| 1.2 | 13.7 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
| 1.2 | 8.6 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
| 1.0 | 4.0 | GO:0005111 | type 2 fibroblast growth factor receptor binding(GO:0005111) |
| 0.9 | 10.9 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
| 0.9 | 4.3 | GO:0005030 | neurotrophin receptor activity(GO:0005030) |
| 0.7 | 3.0 | GO:0015143 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
| 0.7 | 3.4 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.7 | 5.5 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
| 0.7 | 2.0 | GO:0004449 | isocitrate dehydrogenase (NAD+) activity(GO:0004449) |
| 0.7 | 1.3 | GO:0004103 | choline kinase activity(GO:0004103) |
| 0.6 | 1.7 | GO:0000033 | alpha-1,3-mannosyltransferase activity(GO:0000033) |
| 0.5 | 1.6 | GO:0005128 | erythropoietin receptor binding(GO:0005128) |
| 0.5 | 1.5 | GO:0004473 | malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) |
| 0.5 | 8.8 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.5 | 5.1 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 0.5 | 3.2 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
| 0.4 | 1.3 | GO:0005436 | sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319) |
| 0.4 | 4.8 | GO:0031802 | type 5 metabotropic glutamate receptor binding(GO:0031802) |
| 0.4 | 2.2 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
| 0.4 | 7.7 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
| 0.4 | 1.7 | GO:0070012 | oligopeptidase activity(GO:0070012) |
| 0.4 | 4.3 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
| 0.4 | 4.1 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.4 | 1.1 | GO:0047192 | 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192) |
| 0.4 | 2.1 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
| 0.3 | 1.4 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
| 0.3 | 2.0 | GO:0044547 | DNA topoisomerase binding(GO:0044547) |
| 0.3 | 4.2 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
| 0.3 | 3.3 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.3 | 1.7 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
| 0.3 | 1.4 | GO:0045545 | syndecan binding(GO:0045545) |
| 0.3 | 1.0 | GO:0036435 | deubiquitinase activator activity(GO:0035800) K48-linked polyubiquitin binding(GO:0036435) |
| 0.2 | 1.2 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
| 0.2 | 4.2 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
| 0.2 | 2.7 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
| 0.2 | 3.9 | GO:0015248 | sterol transporter activity(GO:0015248) |
| 0.2 | 2.0 | GO:0061676 | importin-alpha family protein binding(GO:0061676) |
| 0.2 | 4.2 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.2 | 3.5 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.2 | 1.9 | GO:1990239 | steroid hormone binding(GO:1990239) |
| 0.2 | 3.9 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.2 | 0.6 | GO:0042954 | lipoprotein transporter activity(GO:0042954) |
| 0.2 | 6.1 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
| 0.2 | 0.8 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
| 0.2 | 2.7 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.2 | 1.4 | GO:0031419 | cobalamin binding(GO:0031419) |
| 0.2 | 1.6 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
| 0.2 | 1.7 | GO:0043995 | histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972) |
| 0.2 | 1.1 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
| 0.2 | 1.9 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.2 | 3.4 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.2 | 2.3 | GO:0005314 | high-affinity glutamate transmembrane transporter activity(GO:0005314) |
| 0.2 | 1.2 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.2 | 2.0 | GO:0016868 | intramolecular transferase activity, phosphotransferases(GO:0016868) |
| 0.2 | 17.0 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
| 0.2 | 7.2 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.2 | 3.2 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.2 | 8.1 | GO:0015459 | potassium channel regulator activity(GO:0015459) |
| 0.2 | 6.5 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.1 | 2.3 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.1 | 0.8 | GO:0030375 | thyroid hormone receptor coactivator activity(GO:0030375) |
| 0.1 | 3.3 | GO:0015215 | nucleotide transmembrane transporter activity(GO:0015215) |
| 0.1 | 11.0 | GO:0000149 | SNARE binding(GO:0000149) |
| 0.1 | 1.4 | GO:0019531 | secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531) |
| 0.1 | 3.6 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.1 | 2.9 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 0.1 | 2.7 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
| 0.1 | 0.6 | GO:0042289 | MHC class II protein binding(GO:0042289) |
| 0.1 | 1.1 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 0.1 | 0.7 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 0.1 | 1.7 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.1 | 2.0 | GO:0070566 | adenylyltransferase activity(GO:0070566) |
| 0.1 | 1.1 | GO:0004576 | oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.1 | 1.9 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.1 | 1.2 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.1 | 1.1 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
| 0.1 | 1.5 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.1 | 1.8 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.1 | 1.4 | GO:0008409 | 5'-3' exonuclease activity(GO:0008409) |
| 0.1 | 0.4 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
| 0.1 | 0.6 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.1 | 2.6 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.1 | 0.3 | GO:0034602 | oxoglutarate dehydrogenase (NAD+) activity(GO:0034602) |
| 0.1 | 5.7 | GO:0050660 | flavin adenine dinucleotide binding(GO:0050660) |
| 0.1 | 1.7 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.1 | 1.3 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.1 | 0.4 | GO:0008312 | 7S RNA binding(GO:0008312) |
| 0.1 | 1.5 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 0.1 | 1.9 | GO:0005179 | hormone activity(GO:0005179) |
| 0.1 | 0.8 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.1 | 0.3 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 0.1 | 1.3 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.1 | 0.9 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 0.1 | 0.2 | GO:0030249 | cyclase regulator activity(GO:0010851) guanylate cyclase regulator activity(GO:0030249) |
| 0.0 | 1.0 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
| 0.0 | 0.7 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.0 | 0.3 | GO:0004689 | phosphorylase kinase activity(GO:0004689) |
| 0.0 | 13.3 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.0 | 3.7 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.0 | 3.5 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 2.8 | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) |
| 0.0 | 1.2 | GO:0008378 | galactosyltransferase activity(GO:0008378) |
| 0.0 | 0.5 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.0 | 1.1 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
| 0.0 | 0.8 | GO:0042605 | peptide antigen binding(GO:0042605) |
| 0.0 | 1.2 | GO:0008375 | acetylglucosaminyltransferase activity(GO:0008375) |
| 0.0 | 1.7 | GO:0004879 | RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531) |
| 0.0 | 1.5 | GO:0001158 | enhancer sequence-specific DNA binding(GO:0001158) |
| 0.0 | 8.5 | GO:0004175 | endopeptidase activity(GO:0004175) |
| 0.0 | 1.6 | GO:0019903 | protein phosphatase binding(GO:0019903) |
| 0.0 | 13.3 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
| 0.0 | 0.5 | GO:0030695 | GTPase regulator activity(GO:0030695) |
| 0.0 | 1.1 | GO:0016876 | aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876) |
| 0.0 | 0.2 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.0 | 6.0 | GO:0008017 | microtubule binding(GO:0008017) |
| 0.0 | 1.0 | GO:0019003 | GDP binding(GO:0019003) |
| 0.0 | 3.5 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.0 | 1.8 | GO:0005525 | GTP binding(GO:0005525) |
| 0.0 | 0.9 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
| 0.0 | 0.1 | GO:0004382 | guanosine-diphosphatase activity(GO:0004382) |
| 0.0 | 0.1 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 0.0 | 0.9 | GO:0008201 | heparin binding(GO:0008201) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 6.4 | PID_TCR_RAS_PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.3 | 18.2 | PID_FOXO_PATHWAY | FoxO family signaling |
| 0.2 | 3.9 | ST_G_ALPHA_S_PATHWAY | G alpha s Pathway |
| 0.2 | 4.8 | PID_NFKAPPAB_CANONICAL_PATHWAY | Canonical NF-kappaB pathway |
| 0.2 | 9.5 | PID_ERBB4_PATHWAY | ErbB4 signaling events |
| 0.1 | 4.2 | PID_ARF_3PATHWAY | Arf1 pathway |
| 0.1 | 6.5 | PID_SHP2_PATHWAY | SHP2 signaling |
| 0.1 | 2.4 | ST_MYOCYTE_AD_PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.1 | 4.3 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
| 0.1 | 2.8 | ST_JNK_MAPK_PATHWAY | JNK MAPK Pathway |
| 0.1 | 2.4 | PID_IL4_2PATHWAY | IL4-mediated signaling events |
| 0.1 | 4.9 | PID_LKB1_PATHWAY | LKB1 signaling events |
| 0.1 | 2.1 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.1 | 1.0 | PID_NEPHRIN_NEPH1_PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
| 0.1 | 2.5 | PID_RETINOIC_ACID_PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.1 | 2.3 | PID_AP1_PATHWAY | AP-1 transcription factor network |
| 0.0 | 2.4 | PID_ERBB1_DOWNSTREAM_PATHWAY | ErbB1 downstream signaling |
| 0.0 | 1.7 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 1.0 | SIG_CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.0 | 0.8 | PID_EPO_PATHWAY | EPO signaling pathway |
| 0.0 | 1.1 | PID_ATF2_PATHWAY | ATF-2 transcription factor network |
| 0.0 | 1.8 | PID_RB_1PATHWAY | Regulation of retinoblastoma protein |
| 0.0 | 1.2 | SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES | Genes related to the insulin receptor pathway |
| 0.0 | 5.0 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 1.3 | PID_HES_HEY_PATHWAY | Notch-mediated HES/HEY network |
| 0.0 | 1.1 | PID_BMP_PATHWAY | BMP receptor signaling |
| 0.0 | 1.0 | PID_MTOR_4PATHWAY | mTOR signaling pathway |
| 0.0 | 1.0 | PID_FANCONI_PATHWAY | Fanconi anemia pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.0 | 13.7 | REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS | Genes involved in Tandem pore domain potassium channels |
| 0.8 | 16.0 | REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 0.7 | 5.6 | REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
| 0.6 | 17.4 | REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION | Genes involved in Unblocking of NMDA receptor, glutamate binding and activation |
| 0.5 | 6.1 | REACTOME_COPI_MEDIATED_TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.5 | 12.0 | REACTOME_SYNTHESIS_OF_PC | Genes involved in Synthesis of PC |
| 0.5 | 4.0 | REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
| 0.5 | 3.0 | REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 0.3 | 2.4 | REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.3 | 4.0 | REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION | Genes involved in FGFR1 ligand binding and activation |
| 0.3 | 12.2 | REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.3 | 9.2 | REACTOME_TIGHT_JUNCTION_INTERACTIONS | Genes involved in Tight junction interactions |
| 0.3 | 3.5 | REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.2 | 6.0 | REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.2 | 8.8 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.1 | 9.3 | REACTOME_COLLAGEN_FORMATION | Genes involved in Collagen formation |
| 0.1 | 2.1 | REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 0.1 | 5.8 | REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.1 | 1.2 | REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.1 | 2.0 | REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
| 0.1 | 1.5 | REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
| 0.1 | 1.2 | REACTOME_KERATAN_SULFATE_DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.1 | 2.3 | REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 0.1 | 1.1 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PG | Genes involved in Acyl chain remodelling of PG |
| 0.1 | 2.4 | REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.1 | 10.7 | REACTOME_G_ALPHA_I_SIGNALLING_EVENTS | Genes involved in G alpha (i) signalling events |
| 0.1 | 2.9 | REACTOME_ERK_MAPK_TARGETS | Genes involved in ERK/MAPK targets |
| 0.1 | 1.2 | REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR | Genes involved in Regulated proteolysis of p75NTR |
| 0.1 | 2.2 | REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING | Genes involved in Growth hormone receptor signaling |
| 0.1 | 2.8 | REACTOME_RAP1_SIGNALLING | Genes involved in Rap1 signalling |
| 0.1 | 1.7 | REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER | Genes involved in Formation of incision complex in GG-NER |
| 0.1 | 7.4 | REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE | Genes involved in SRP-dependent cotranslational protein targeting to membrane |
| 0.1 | 1.4 | REACTOME_PERK_REGULATED_GENE_EXPRESSION | Genes involved in PERK regulated gene expression |
| 0.1 | 3.7 | REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.1 | 1.1 | REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
| 0.0 | 1.2 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI | Genes involved in N-glycan antennae elongation in the medial/trans-Golgi |
| 0.0 | 1.0 | REACTOME_FANCONI_ANEMIA_PATHWAY | Genes involved in Fanconi Anemia pathway |
| 0.0 | 4.5 | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.0 | 2.0 | REACTOME_MRNA_3_END_PROCESSING | Genes involved in mRNA 3'-end processing |
| 0.0 | 0.7 | REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE | Genes involved in NGF signalling via TRKA from the plasma membrane |
| 0.0 | 2.6 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.0 | 1.5 | REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE | Genes involved in GPVI-mediated activation cascade |
| 0.0 | 1.2 | REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.0 | 1.2 | REACTOME_SIGNALING_BY_ROBO_RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.0 | 0.4 | REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.0 | 0.3 | REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.0 | 0.3 | REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 0.0 | 0.2 | REACTOME_ZINC_TRANSPORTERS | Genes involved in Zinc transporters |
| 0.0 | 0.5 | REACTOME_IL1_SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.0 | 0.2 | REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
