Motif ID: Barhl1

Z-value: 0.539


Transcription factors associated with Barhl1:

Gene SymbolEntrez IDGene Name
Barhl1 ENSMUSG00000026805.8 Barhl1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Barhl1mm10_v2_chr2_-_28916668_28916668-0.076.3e-01Click!


Activity profile for motif Barhl1.

activity profile for motif Barhl1


Sorted Z-values histogram for motif Barhl1

Sorted Z-values for motif Barhl1



Network of associatons between targets according to the STRING database.



First level regulatory network of Barhl1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 52 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_43869993 3.122 ENSMUST00000067469.4
 Tmem74
transmembrane protein 74
chr16_+_92292380 2.297 ENSMUST00000047383.3
 Kcne2
potassium voltage-gated channel, Isk-related subfamily, gene 2
chr16_+_10827921 2.173 ENSMUST00000181732.1
 Gm26822
predicted gene, 26822
chr3_-_146770603 1.980 ENSMUST00000106138.1
 Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr15_-_53902472 1.942 ENSMUST00000078673.6
 Samd12
sterile alpha motif domain containing 12
chr3_-_146770218 1.801 ENSMUST00000106137.1
 Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr18_+_37355271 1.728 ENSMUST00000051163.1
 Pcdhb8
protocadherin beta 8
chr1_+_115684727 1.705 ENSMUST00000043725.7
 Cntnap5a
contactin associated protein-like 5A
chr5_-_62766153 1.487 ENSMUST00000076623.4
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr6_-_41636389 1.417 ENSMUST00000031902.5
 Trpv6
transient receptor potential cation channel, subfamily V, member 6
chr2_-_45110336 1.335 ENSMUST00000028229.6
ENSMUST00000152232.1
 Zeb2

zinc finger E-box binding homeobox 2

chr3_+_116008220 1.098 ENSMUST00000106502.1
 Extl2
exostoses (multiple)-like 2
chr16_-_32868325 1.095 ENSMUST00000089684.3
ENSMUST00000040986.8
ENSMUST00000115105.2
 1700021K19Rik


RIKEN cDNA 1700021K19 gene


chr6_-_59426279 1.055 ENSMUST00000051065.4
 Gprin3
GPRIN family member 3
chr11_+_22971991 1.040 ENSMUST00000049506.5
 Zrsr1
zinc finger (CCCH type), RNA binding motif and serine/arginine rich 1
chr6_+_72097561 1.035 ENSMUST00000069994.4
ENSMUST00000114112.1
 St3gal5

ST3 beta-galactoside alpha-2,3-sialyltransferase 5

chr17_-_78418083 1.031 ENSMUST00000070039.7
ENSMUST00000112487.1
 Fez2

fasciculation and elongation protein zeta 2 (zygin II)

chr11_+_102430315 0.959 ENSMUST00000049460.4
ENSMUST00000129997.1
 Grn

granulin

chr15_+_55112317 0.951 ENSMUST00000096433.3
 Deptor
DEP domain containing MTOR-interacting protein
chr7_+_45896941 0.931 ENSMUST00000069772.7
ENSMUST00000107716.1
 Tmem143

transmembrane protein 143


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 3.8 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 3.1 GO:0016236 macroautophagy(GO:0016236)
0.4 2.3 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.2 1.4 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.2 1.3 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.3 1.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 1.1 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.1 1.0 GO:0035188 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1 1.0 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 1.0 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.9 GO:0043171 peptide catabolic process(GO:0043171)
0.1 0.6 GO:1990009 retinal cell apoptotic process(GO:1990009)
0.1 0.6 GO:0031642 negative regulation of myelination(GO:0031642)
0.1 0.6 GO:0038203 TORC2 signaling(GO:0038203)
0.2 0.5 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.2 0.5 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0 0.5 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.4 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.1 0.3 GO:0051030 snRNA transport(GO:0051030)
0.0 0.2 GO:1901550 regulation of endothelial cell development(GO:1901550) regulation of establishment of endothelial barrier(GO:1903140)

Gene overrepresentation in cellular_component category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 3.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 2.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 1.0 GO:0089701 U2AF(GO:0089701)
0.2 0.9 GO:0031983 vesicle lumen(GO:0031983)
0.2 0.9 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.6 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.5 GO:0071437 invadopodium(GO:0071437)
0.0 0.4 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 3.8 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.5 2.3 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0 1.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 1.7 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 1.4 GO:0005262 calcium channel activity(GO:0005262)
0.0 1.3 GO:0070412 R-SMAD binding(GO:0070412)
0.4 1.1 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.1 1.0 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 1.0 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.6 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1 0.6 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.6 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.6 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 0.5 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.4 GO:1990460 leptin receptor binding(GO:1990460)
0.1 0.3 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.2 GO:0031489 myosin V binding(GO:0031489)

Gene overrepresentation in C2:CP category:

Showing 1 to 6 of 6 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.8 PID_IL3_PATHWAY IL3-mediated signaling events
0.0 1.8 PID_ARF6_PATHWAY Arf6 signaling events
0.0 1.4 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.0 1.0 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.5 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.0 0.3 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 3.8 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 1.8 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.6 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.6 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.5 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.5 REACTOME_CA_DEPENDENT_EVENTS Genes involved in Ca-dependent events
0.0 0.3 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis