Motif ID: Bcl6
Z-value: 0.675
Transcription factors associated with Bcl6:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Bcl6 | ENSMUSG00000022508.5 | Bcl6 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Bcl6 | mm10_v2_chr16_-_23988852_23988852 | 0.69 | 4.1e-09 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 4.0 | GO:0033024 | mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) |
| 0.8 | 3.3 | GO:0014012 | peripheral nervous system axon regeneration(GO:0014012) |
| 0.8 | 2.3 | GO:0071492 | cellular response to UV-A(GO:0071492) |
| 0.7 | 4.0 | GO:0097646 | calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647) |
| 0.7 | 2.0 | GO:1903538 | meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538) |
| 0.6 | 2.6 | GO:0072137 | condensed mesenchymal cell proliferation(GO:0072137) |
| 0.6 | 1.9 | GO:0035585 | calcium-mediated signaling using extracellular calcium source(GO:0035585) |
| 0.6 | 2.3 | GO:1904457 | positive regulation of neuronal action potential(GO:1904457) |
| 0.5 | 2.2 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
| 0.5 | 5.4 | GO:0042572 | retinol metabolic process(GO:0042572) |
| 0.5 | 1.5 | GO:2000331 | regulation of terminal button organization(GO:2000331) |
| 0.5 | 1.4 | GO:0010751 | regulation of arginine metabolic process(GO:0000821) negative regulation of nitric oxide mediated signal transduction(GO:0010751) negative regulation of cellular amino acid metabolic process(GO:0045763) |
| 0.4 | 4.4 | GO:0010650 | positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
| 0.4 | 2.3 | GO:0007021 | tubulin complex assembly(GO:0007021) |
| 0.3 | 2.3 | GO:0034638 | phosphatidylcholine catabolic process(GO:0034638) |
| 0.3 | 2.1 | GO:0015862 | uridine transport(GO:0015862) |
| 0.3 | 0.9 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
| 0.3 | 1.4 | GO:0048245 | eosinophil chemotaxis(GO:0048245) |
| 0.3 | 1.7 | GO:0035356 | cellular triglyceride homeostasis(GO:0035356) |
| 0.3 | 1.6 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
| 0.2 | 2.7 | GO:0097421 | liver regeneration(GO:0097421) |
| 0.2 | 1.0 | GO:0060332 | positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335) |
| 0.2 | 3.6 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
| 0.2 | 0.9 | GO:0006478 | peptidyl-tyrosine sulfation(GO:0006478) |
| 0.2 | 0.9 | GO:0010756 | positive regulation of plasminogen activation(GO:0010756) |
| 0.2 | 4.8 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
| 0.2 | 0.6 | GO:0070973 | COPI-coated vesicle budding(GO:0035964) protein localization to endoplasmic reticulum exit site(GO:0070973) |
| 0.2 | 1.5 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
| 0.2 | 0.9 | GO:0046684 | response to pyrethroid(GO:0046684) |
| 0.2 | 0.6 | GO:0002182 | cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248) |
| 0.2 | 1.4 | GO:0005513 | detection of calcium ion(GO:0005513) |
| 0.2 | 0.4 | GO:2000587 | negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587) |
| 0.2 | 0.7 | GO:1903028 | regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028) |
| 0.2 | 0.5 | GO:0006436 | tryptophanyl-tRNA aminoacylation(GO:0006436) |
| 0.2 | 0.5 | GO:1902022 | ovarian follicle rupture(GO:0001543) angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998) regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) regulation of activation of Janus kinase activity(GO:0010533) L-lysine transport(GO:1902022) |
| 0.2 | 1.3 | GO:0061368 | maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368) |
| 0.2 | 0.8 | GO:1900122 | positive regulation of receptor binding(GO:1900122) |
| 0.2 | 3.6 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
| 0.1 | 4.5 | GO:0045736 | negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030) |
| 0.1 | 0.3 | GO:0035482 | gastric motility(GO:0035482) gastric emptying(GO:0035483) |
| 0.1 | 7.4 | GO:0045744 | negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744) |
| 0.1 | 0.9 | GO:0032026 | response to magnesium ion(GO:0032026) |
| 0.1 | 0.8 | GO:0002904 | positive regulation of B cell apoptotic process(GO:0002904) |
| 0.1 | 0.7 | GO:0030643 | cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502) |
| 0.1 | 0.4 | GO:0070212 | protein poly-ADP-ribosylation(GO:0070212) |
| 0.1 | 0.8 | GO:0071494 | cellular response to UV-C(GO:0071494) |
| 0.1 | 0.9 | GO:0061470 | interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619) |
| 0.1 | 1.0 | GO:0045607 | regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980) |
| 0.1 | 0.6 | GO:0032261 | purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264) |
| 0.1 | 0.3 | GO:0097212 | cleavage furrow ingression(GO:0036090) lysosomal membrane organization(GO:0097212) |
| 0.1 | 1.0 | GO:0048266 | behavioral response to pain(GO:0048266) |
| 0.1 | 0.4 | GO:0019236 | response to pheromone(GO:0019236) |
| 0.1 | 3.0 | GO:0045071 | negative regulation of viral genome replication(GO:0045071) |
| 0.1 | 0.4 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 0.1 | 0.3 | GO:0009449 | gamma-aminobutyric acid biosynthetic process(GO:0009449) |
| 0.1 | 0.2 | GO:0051794 | regulation of catagen(GO:0051794) |
| 0.1 | 0.4 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
| 0.0 | 0.3 | GO:0015808 | L-alanine transport(GO:0015808) |
| 0.0 | 1.1 | GO:0099517 | anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517) |
| 0.0 | 0.5 | GO:0060134 | prepulse inhibition(GO:0060134) |
| 0.0 | 0.2 | GO:2000048 | negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048) |
| 0.0 | 1.8 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.0 | 0.8 | GO:0071378 | growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378) |
| 0.0 | 3.1 | GO:0003073 | regulation of systemic arterial blood pressure(GO:0003073) |
| 0.0 | 1.1 | GO:0046470 | phosphatidylcholine metabolic process(GO:0046470) |
| 0.0 | 0.3 | GO:0046415 | urate metabolic process(GO:0046415) |
| 0.0 | 0.4 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.0 | 0.9 | GO:0035025 | positive regulation of Rho protein signal transduction(GO:0035025) |
| 0.0 | 0.3 | GO:0015868 | purine ribonucleotide transport(GO:0015868) |
| 0.0 | 0.1 | GO:0060709 | glycogen cell differentiation involved in embryonic placenta development(GO:0060709) |
| 0.0 | 0.4 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 0.0 | 0.1 | GO:0021529 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) |
| 0.0 | 0.1 | GO:0090611 | ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611) |
| 0.0 | 1.3 | GO:0034605 | cellular response to heat(GO:0034605) |
| 0.0 | 0.3 | GO:2000807 | regulation of synaptic vesicle clustering(GO:2000807) |
| 0.0 | 0.9 | GO:0008333 | endosome to lysosome transport(GO:0008333) |
| 0.0 | 1.2 | GO:0001541 | ovarian follicle development(GO:0001541) |
| 0.0 | 0.2 | GO:0045654 | positive regulation of megakaryocyte differentiation(GO:0045654) |
| 0.0 | 0.1 | GO:0010735 | positive regulation of transcription via serum response element binding(GO:0010735) |
| 0.0 | 0.1 | GO:0060753 | regulation of mast cell chemotaxis(GO:0060753) |
| 0.0 | 0.3 | GO:0046688 | response to copper ion(GO:0046688) |
| 0.0 | 0.1 | GO:0060923 | cardiac muscle cell fate commitment(GO:0060923) |
| 0.0 | 0.5 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
| 0.0 | 0.3 | GO:0002446 | neutrophil mediated immunity(GO:0002446) |
| 0.0 | 2.5 | GO:0007416 | synapse assembly(GO:0007416) |
| 0.0 | 3.5 | GO:0043547 | positive regulation of GTPase activity(GO:0043547) |
| 0.0 | 1.3 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
| 0.0 | 0.1 | GO:1901978 | positive regulation of cell cycle checkpoint(GO:1901978) |
| 0.0 | 0.3 | GO:0001937 | negative regulation of endothelial cell proliferation(GO:0001937) |
| 0.0 | 1.8 | GO:0048813 | dendrite morphogenesis(GO:0048813) |
| 0.0 | 0.2 | GO:0072337 | modified amino acid transport(GO:0072337) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 4.0 | GO:1903440 | calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440) |
| 0.5 | 2.7 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
| 0.5 | 1.6 | GO:0005940 | septin ring(GO:0005940) |
| 0.5 | 1.9 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
| 0.5 | 2.3 | GO:0044316 | cone cell pedicle(GO:0044316) |
| 0.4 | 2.3 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 0.3 | 4.4 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.3 | 4.4 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
| 0.2 | 0.6 | GO:0044299 | C-fiber(GO:0044299) |
| 0.2 | 0.9 | GO:0001652 | granular component(GO:0001652) |
| 0.2 | 3.1 | GO:0044292 | dendrite terminus(GO:0044292) |
| 0.2 | 3.6 | GO:0032279 | asymmetric synapse(GO:0032279) |
| 0.1 | 1.6 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.1 | 0.9 | GO:0042627 | chylomicron(GO:0042627) |
| 0.1 | 0.8 | GO:0070695 | FHF complex(GO:0070695) |
| 0.1 | 0.4 | GO:0097447 | dendritic tree(GO:0097447) |
| 0.1 | 3.3 | GO:0031672 | A band(GO:0031672) |
| 0.1 | 0.3 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.1 | 1.1 | GO:0030123 | AP-3 adaptor complex(GO:0030123) |
| 0.1 | 1.4 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.1 | 0.9 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.1 | 1.0 | GO:0044754 | autolysosome(GO:0044754) |
| 0.0 | 0.6 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.0 | 0.2 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
| 0.0 | 1.8 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 0.4 | GO:0005840 | ribosome(GO:0005840) |
| 0.0 | 2.9 | GO:0005903 | brush border(GO:0005903) |
| 0.0 | 1.4 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.0 | 0.6 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.0 | 3.4 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.0 | 0.1 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 0.0 | 0.5 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.0 | 3.7 | GO:0000139 | Golgi membrane(GO:0000139) |
| 0.0 | 0.2 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 4.0 | GO:0097643 | amylin receptor activity(GO:0097643) |
| 0.8 | 5.4 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 0.7 | 4.0 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
| 0.6 | 3.6 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
| 0.6 | 1.8 | GO:0003846 | 2-acylglycerol O-acyltransferase activity(GO:0003846) |
| 0.6 | 2.3 | GO:0004528 | phosphodiesterase I activity(GO:0004528) |
| 0.6 | 4.5 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.6 | 3.3 | GO:0045545 | syndecan binding(GO:0045545) |
| 0.5 | 3.6 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
| 0.4 | 2.2 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.3 | 3.1 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
| 0.3 | 4.1 | GO:0030247 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
| 0.3 | 0.8 | GO:0000099 | sulfur amino acid transmembrane transporter activity(GO:0000099) L-asparagine transmembrane transporter activity(GO:0015182) |
| 0.3 | 2.3 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.2 | 1.2 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
| 0.2 | 0.9 | GO:0008476 | protein-tyrosine sulfotransferase activity(GO:0008476) |
| 0.2 | 8.5 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.2 | 0.8 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
| 0.2 | 0.5 | GO:0004830 | tryptophan-tRNA ligase activity(GO:0004830) |
| 0.2 | 0.6 | GO:0031727 | CCR2 chemokine receptor binding(GO:0031727) |
| 0.1 | 0.8 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
| 0.1 | 0.9 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
| 0.1 | 3.8 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.1 | 0.4 | GO:0015038 | glutathione disulfide oxidoreductase activity(GO:0015038) protein-disulfide reductase (glutathione) activity(GO:0019153) |
| 0.1 | 1.6 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
| 0.1 | 0.3 | GO:0015173 | hydrogen:amino acid symporter activity(GO:0005280) aromatic amino acid transmembrane transporter activity(GO:0015173) |
| 0.1 | 6.4 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.1 | 1.1 | GO:0004622 | lysophospholipase activity(GO:0004622) |
| 0.1 | 1.4 | GO:0030346 | protein phosphatase 2B binding(GO:0030346) |
| 0.1 | 1.4 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.1 | 1.5 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.1 | 0.6 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.1 | 3.5 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
| 0.1 | 2.1 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |
| 0.1 | 0.3 | GO:0015143 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
| 0.1 | 0.9 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
| 0.1 | 0.2 | GO:0015220 | choline transmembrane transporter activity(GO:0015220) |
| 0.1 | 1.3 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
| 0.1 | 0.3 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.1 | 0.3 | GO:0004322 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.1 | 2.3 | GO:0030552 | cAMP binding(GO:0030552) |
| 0.1 | 2.0 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.1 | 0.9 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.0 | 1.2 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.0 | 0.8 | GO:0048018 | receptor agonist activity(GO:0048018) |
| 0.0 | 0.9 | GO:0017110 | nucleoside-diphosphatase activity(GO:0017110) |
| 0.0 | 0.3 | GO:0004351 | glutamate decarboxylase activity(GO:0004351) |
| 0.0 | 0.4 | GO:0001846 | opsonin binding(GO:0001846) |
| 0.0 | 1.3 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.0 | 1.2 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.0 | 0.6 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.0 | 0.4 | GO:0009922 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.0 | 0.5 | GO:0031702 | angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702) |
| 0.0 | 5.2 | GO:0008237 | metallopeptidase activity(GO:0008237) |
| 0.0 | 0.3 | GO:0016004 | phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229) |
| 0.0 | 1.8 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 0.0 | 0.8 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.0 | 0.4 | GO:0070403 | NAD+ binding(GO:0070403) |
| 0.0 | 0.7 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.0 | 1.0 | GO:0051018 | protein kinase A binding(GO:0051018) |
| 0.0 | 1.3 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
| 0.0 | 3.1 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.0 | 0.7 | GO:0043531 | ADP binding(GO:0043531) |
| 0.0 | 0.5 | GO:0051721 | protein phosphatase 2A binding(GO:0051721) |
| 0.0 | 0.4 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.0 | 1.1 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 0.7 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 0.1 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.0 | 2.1 | GO:0005057 | receptor signaling protein activity(GO:0005057) |
| 0.0 | 0.8 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.0 | 0.2 | GO:0004576 | oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.0 | 0.3 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.0 | 1.3 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.0 | 0.1 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 4.8 | ST_INTERFERON_GAMMA_PATHWAY | Interferon gamma pathway. |
| 0.2 | 2.7 | PID_INTEGRIN5_PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.1 | 3.3 | PID_INTEGRIN_A9B1_PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.1 | 3.5 | PID_NCADHERIN_PATHWAY | N-cadherin signaling events |
| 0.1 | 4.6 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 1.4 | PID_FRA_PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.0 | 1.2 | PID_ARF6_DOWNSTREAM_PATHWAY | Arf6 downstream pathway |
| 0.0 | 1.6 | PID_ECADHERIN_STABILIZATION_PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.0 | 1.5 | PID_AJDISS_2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.0 | 4.1 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 1.8 | PID_INSULIN_PATHWAY | Insulin Pathway |
| 0.0 | 0.6 | PID_ARF_3PATHWAY | Arf1 pathway |
| 0.0 | 0.8 | SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.0 | 0.9 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
| 0.0 | 0.4 | PID_IL4_2PATHWAY | IL4-mediated signaling events |
| 0.0 | 0.5 | PID_MAPK_TRK_PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 3.8 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.2 | 3.6 | REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
| 0.1 | 5.4 | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.1 | 4.4 | REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING | Genes involved in Growth hormone receptor signaling |
| 0.1 | 7.8 | REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS | Genes involved in G alpha (z) signalling events |
| 0.1 | 1.9 | REACTOME_TIE2_SIGNALING | Genes involved in Tie2 Signaling |
| 0.1 | 1.5 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.1 | 8.2 | REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.1 | 0.6 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.1 | 1.1 | REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.1 | 0.4 | REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
| 0.1 | 0.8 | REACTOME_COPI_MEDIATED_TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.1 | 3.3 | REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.1 | 1.4 | REACTOME_CGMP_EFFECTS | Genes involved in cGMP effects |
| 0.1 | 0.8 | REACTOME_ACTIVATION_OF_RAC | Genes involved in Activation of Rac |
| 0.1 | 2.1 | REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.1 | 1.2 | REACTOME_SYNTHESIS_OF_PC | Genes involved in Synthesis of PC |
| 0.0 | 0.6 | REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.0 | 3.6 | REACTOME_G_ALPHA_I_SIGNALLING_EVENTS | Genes involved in G alpha (i) signalling events |
| 0.0 | 1.6 | REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.0 | 2.2 | REACTOME_TRIGLYCERIDE_BIOSYNTHESIS | Genes involved in Triglyceride Biosynthesis |
| 0.0 | 0.6 | REACTOME_PURINE_SALVAGE | Genes involved in Purine salvage |
| 0.0 | 0.7 | REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.0 | 0.3 | REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.0 | 0.5 | REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
| 0.0 | 0.3 | REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS | Genes involved in Class A/1 (Rhodopsin-like receptors) |
| 0.0 | 1.3 | REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS | Genes involved in G alpha (q) signalling events |
| 0.0 | 2.6 | REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES | Genes involved in Transmission across Chemical Synapses |
| 0.0 | 0.4 | REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.0 | 0.3 | REACTOME_METAL_ION_SLC_TRANSPORTERS | Genes involved in Metal ion SLC transporters |
| 0.0 | 0.3 | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
