Motif ID: Bcl6b

Z-value: 0.486


Transcription factors associated with Bcl6b:

Gene SymbolEntrez IDGene Name
Bcl6b ENSMUSG00000000317.5 Bcl6b

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bcl6bmm10_v2_chr11_-_70229677_702297610.162.4e-01Click!


Activity profile for motif Bcl6b.

activity profile for motif Bcl6b


Sorted Z-values histogram for motif Bcl6b

Sorted Z-values for motif Bcl6b



Network of associatons between targets according to the STRING database.



First level regulatory network of Bcl6b

PNG image of the network

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Top targets:


Showing 1 to 20 of 71 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_64046925 3.665 ENSMUST00000107377.3
 Tnc
tenascin C
chr19_-_5797410 2.579 ENSMUST00000173314.1
 Malat1
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chr16_-_74411776 2.023 ENSMUST00000116586.2
 Robo2
roundabout homolog 2 (Drosophila)
chr1_-_173942445 1.975 ENSMUST00000042228.8
ENSMUST00000081216.5
ENSMUST00000129829.1
ENSMUST00000123708.1
ENSMUST00000111210.2
 Ifi203



Mndal
interferon activated gene 203



myeloid nuclear differentiation antigen like
chr10_+_57794335 1.754 ENSMUST00000151623.1
ENSMUST00000020022.7
 Smpdl3a

sphingomyelin phosphodiesterase, acid-like 3A

chrX_+_151344171 1.599 ENSMUST00000073364.5
 Fam120c
family with sequence similarity 120, member C
chr16_-_74411292 1.591 ENSMUST00000117200.1
 Robo2
roundabout homolog 2 (Drosophila)
chr9_-_90255927 1.553 ENSMUST00000144646.1
 Tbc1d2b
TBC1 domain family, member 2B
chr13_-_98815408 1.378 ENSMUST00000040340.8
ENSMUST00000099277.4
ENSMUST00000179563.1
ENSMUST00000109403.1
 Fcho2



FCH domain only 2



chr16_-_34263179 1.138 ENSMUST00000114949.1
ENSMUST00000114954.1
 Kalrn

kalirin, RhoGEF kinase

chr12_-_40134175 1.101 ENSMUST00000078481.7
ENSMUST00000002640.5
 Scin

scinderin

chr2_+_119594288 1.079 ENSMUST00000147425.1
ENSMUST00000153581.1
 1700020I14Rik

RIKEN cDNA 1700020I14 gene

chr16_-_34262830 1.069 ENSMUST00000114947.1
 Kalrn
kalirin, RhoGEF kinase
chr2_-_65567505 1.015 ENSMUST00000100069.2
 Scn3a
sodium channel, voltage-gated, type III, alpha
chr2_-_65567465 1.000 ENSMUST00000066432.5
 Scn3a
sodium channel, voltage-gated, type III, alpha
chr6_+_149309444 0.989 ENSMUST00000100765.4
 2810474O19Rik
RIKEN cDNA 2810474O19 gene
chr6_+_149309391 0.983 ENSMUST00000130664.1
ENSMUST00000046689.6
 2810474O19Rik

RIKEN cDNA 2810474O19 gene

chr12_-_98577940 0.979 ENSMUST00000110113.1
 Kcnk10
potassium channel, subfamily K, member 10
chr8_+_13907748 0.968 ENSMUST00000043520.3
 Fbxo25
F-box protein 25
chr10_+_81633694 0.957 ENSMUST00000140345.1
ENSMUST00000126323.1
 Ankrd24

ankyrin repeat domain 24


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 3.7 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
1.2 3.6 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.4 3.0 GO:0061368 maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.5 2.6 GO:0035063 nuclear speck organization(GO:0035063)
0.4 2.0 GO:0046684 response to pyrethroid(GO:0046684)
0.1 2.0 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.3 1.8 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 1.6 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 1.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.3 1.3 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.1 1.2 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.2 1.1 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 1.0 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.9 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.9 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.2 0.7 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.1 0.5 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.5 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.4 GO:0071318 cellular response to ATP(GO:0071318)
0.1 0.3 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)

Gene overrepresentation in cellular_component category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 3.7 GO:0005614 interstitial matrix(GO:0005614)
0.1 3.6 GO:0030673 axolemma(GO:0030673)
0.1 2.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.5 1.4 GO:0098835 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.0 1.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.9 GO:0016459 myosin complex(GO:0016459)
0.0 0.9 GO:0031985 Golgi cisterna(GO:0031985)
0.1 0.7 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 0.5 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.5 GO:0030478 actin cap(GO:0030478)
0.0 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.3 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 0.2 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)

Gene overrepresentation in molecular_function category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 3.7 GO:0045545 syndecan binding(GO:0045545)
0.5 3.6 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 3.0 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 2.0 GO:0031402 sodium ion binding(GO:0031402)
0.2 1.8 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 1.4 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 1.3 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 1.2 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 1.0 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.9 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.9 GO:0030507 spectrin binding(GO:0030507)
0.0 0.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.4 GO:0046790 virion binding(GO:0046790)
0.1 0.3 GO:0015265 urea channel activity(GO:0015265)
0.1 0.2 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.0 0.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.2 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 0.1 GO:0000992 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)

Gene overrepresentation in C2:CP category:

Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.7 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.1 3.0 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 0.9 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.9 PID_IL2_1PATHWAY IL2-mediated signaling events
0.0 0.5 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.6 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 3.5 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 3.0 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.1 1.0 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.9 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.9 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.5 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.3 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.2 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1