Motif ID: Cebpa_Cebpg

Z-value: 0.577

Transcription factors associated with Cebpa_Cebpg:

Gene SymbolEntrez IDGene Name
Cebpa ENSMUSG00000034957.9 Cebpa
Cebpg ENSMUSG00000056216.8 Cebpg

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cebpgmm10_v2_chr7_-_35056467_35056556-0.524.3e-05Click!
Cebpamm10_v2_chr7_+_35119285_351193010.211.3e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Cebpa_Cebpg

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_57239310 5.607 ENSMUST00000111559.1
Ablim1
actin-binding LIM protein 1
chr9_-_121495678 4.284 ENSMUST00000035120.4
Cck
cholecystokinin
chr6_+_17463749 3.522 ENSMUST00000115443.1
Met
met proto-oncogene
chrX_-_162565514 3.069 ENSMUST00000154424.1
Reps2
RALBP1 associated Eps domain containing protein 2
chr13_-_117025505 2.985 ENSMUST00000022239.6
Parp8
poly (ADP-ribose) polymerase family, member 8
chr1_-_22315792 2.973 ENSMUST00000164877.1
Rims1
regulating synaptic membrane exocytosis 1
chr7_-_103813913 2.866 ENSMUST00000098192.3
Hbb-bt
hemoglobin, beta adult t chain
chr1_-_38821215 2.666 ENSMUST00000039612.4
Lonrf2
LON peptidase N-terminal domain and ring finger 2
chr12_+_74297474 2.489 ENSMUST00000072100.3
Dbpht2
DNA binding protein with his-thr domain
chr14_+_65970610 2.010 ENSMUST00000127387.1
Clu
clusterin
chr4_-_15149051 1.882 ENSMUST00000041606.7
Necab1
N-terminal EF-hand calcium binding protein 1
chr14_+_65971049 1.758 ENSMUST00000128539.1
Clu
clusterin
chr2_-_45117349 1.623 ENSMUST00000176438.2
Zeb2
zinc finger E-box binding homeobox 2
chr1_+_169655493 1.527 ENSMUST00000027997.3
Rgs5
regulator of G-protein signaling 5
chr4_-_15149755 1.512 ENSMUST00000108273.1
Necab1
N-terminal EF-hand calcium binding protein 1
chr13_-_49309217 1.482 ENSMUST00000110087.2
Fgd3
FYVE, RhoGEF and PH domain containing 3
chr1_-_71653162 1.358 ENSMUST00000055226.6
Fn1
fibronectin 1
chr2_-_65567465 1.332 ENSMUST00000066432.5
Scn3a
sodium channel, voltage-gated, type III, alpha
chr4_+_85205120 1.293 ENSMUST00000107188.3
Sh3gl2
SH3-domain GRB2-like 2
chr14_+_65970804 1.274 ENSMUST00000138191.1
Clu
clusterin
chr3_+_31902666 1.247 ENSMUST00000119970.1
ENSMUST00000178668.1
Kcnmb2

potassium large conductance calcium-activated channel, subfamily M, beta member 2

chr13_+_109903089 1.217 ENSMUST00000120664.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr2_-_65567505 1.214 ENSMUST00000100069.2
Scn3a
sodium channel, voltage-gated, type III, alpha
chr6_+_96115249 1.188 ENSMUST00000075080.5
Fam19a1
family with sequence similarity 19, member A1
chr1_-_37496095 1.169 ENSMUST00000148047.1
ENSMUST00000143636.1
Mgat4a

mannoside acetylglucosaminyltransferase 4, isoenzyme A

chr11_-_42000834 1.139 ENSMUST00000070725.4
Gabrg2
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr11_-_35798884 1.123 ENSMUST00000160726.2
Fbll1
fibrillarin-like 1
chr14_+_65971164 1.121 ENSMUST00000144619.1
Clu
clusterin
chr9_+_37367354 1.067 ENSMUST00000051839.7
Hepacam
hepatocyte cell adhesion molecule
chrX_+_73064787 1.046 ENSMUST00000060418.6
Pnma3
paraneoplastic antigen MA3
chr11_-_120643643 0.973 ENSMUST00000141254.1
ENSMUST00000170556.1
ENSMUST00000151876.1
ENSMUST00000026133.8
ENSMUST00000139706.1
Pycr1




pyrroline-5-carboxylate reductase 1




chr3_-_142169196 0.943 ENSMUST00000098568.1
Bmpr1b
bone morphogenetic protein receptor, type 1B
chr13_+_31806627 0.925 ENSMUST00000062292.2
Foxc1
forkhead box C1
chr3_+_19957037 0.904 ENSMUST00000091309.5
ENSMUST00000108329.1
ENSMUST00000003714.6
Cp


ceruloplasmin


chr18_+_37489465 0.903 ENSMUST00000055949.2
Pcdhb18
protocadherin beta 18
chr11_-_110095937 0.858 ENSMUST00000106664.3
ENSMUST00000046223.7
ENSMUST00000106662.1
Abca8a


ATP-binding cassette, sub-family A (ABC1), member 8a


chr6_-_7693184 0.823 ENSMUST00000031766.5
Asns
asparagine synthetase
chr3_+_129532386 0.822 ENSMUST00000071402.2
Elovl6
ELOVL family member 6, elongation of long chain fatty acids (yeast)
chr13_+_24614608 0.801 ENSMUST00000091694.3
Fam65b
family with sequence similarity 65, member B
chr2_-_52676571 0.776 ENSMUST00000178799.1
Cacnb4
calcium channel, voltage-dependent, beta 4 subunit
chr11_-_84870712 0.771 ENSMUST00000170741.1
ENSMUST00000172405.1
ENSMUST00000100686.3
ENSMUST00000108081.2
Ggnbp2



gametogenetin binding protein 2



chr3_-_142169311 0.742 ENSMUST00000106230.1
Bmpr1b
bone morphogenetic protein receptor, type 1B
chr10_-_102490418 0.676 ENSMUST00000020040.3
Nts
neurotensin
chr11_-_84870646 0.674 ENSMUST00000018547.2
Ggnbp2
gametogenetin binding protein 2
chr10_+_69925766 0.672 ENSMUST00000182269.1
ENSMUST00000183261.1
ENSMUST00000183074.1
Ank3


ankyrin 3, epithelial


chr6_-_99028874 0.660 ENSMUST00000154163.2
Foxp1
forkhead box P1
chr10_+_69925484 0.643 ENSMUST00000182692.1
ENSMUST00000092433.5
Ank3

ankyrin 3, epithelial

chr14_-_18893376 0.626 ENSMUST00000151926.1
Ube2e2
ubiquitin-conjugating enzyme E2E 2
chr9_+_94669876 0.616 ENSMUST00000033463.9
Slc9a9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr16_-_34095983 0.614 ENSMUST00000114973.1
ENSMUST00000114964.1
Kalrn

kalirin, RhoGEF kinase

chr3_-_50443603 0.607 ENSMUST00000029297.4
Slc7a11
solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
chr11_-_106216318 0.606 ENSMUST00000002043.3
Ccdc47
coiled-coil domain containing 47
chr2_+_82053222 0.583 ENSMUST00000047527.7
Zfp804a
zinc finger protein 804A
chr16_+_3847206 0.577 ENSMUST00000041778.7
Zfp174
zinc finger protein 174
chr18_-_64516547 0.574 ENSMUST00000025483.9
Nars
asparaginyl-tRNA synthetase
chr14_+_51091077 0.557 ENSMUST00000022428.5
ENSMUST00000171688.1
Rnase4
Ang
ribonuclease, RNase A family 4
angiogenin, ribonuclease, RNase A family, 5
chr5_-_51567717 0.556 ENSMUST00000127135.1
ENSMUST00000151104.1
Ppargc1a

peroxisome proliferative activated receptor, gamma, coactivator 1 alpha

chr7_-_79149042 0.542 ENSMUST00000032825.8
ENSMUST00000107409.3
Mfge8

milk fat globule-EGF factor 8 protein

chr11_+_53433299 0.534 ENSMUST00000018382.6
Gdf9
growth differentiation factor 9
chr8_-_86580664 0.533 ENSMUST00000131423.1
ENSMUST00000152438.1
Abcc12

ATP-binding cassette, sub-family C (CFTR/MRP), member 12

chr11_-_84870812 0.525 ENSMUST00000168434.1
Ggnbp2
gametogenetin binding protein 2
chrX_+_74297097 0.521 ENSMUST00000019231.5
ENSMUST00000147900.1
ENSMUST00000147275.1
ENSMUST00000114171.3
Atp6ap1



ATPase, H+ transporting, lysosomal accessory protein 1



chr4_+_136143497 0.519 ENSMUST00000008016.2
Id3
inhibitor of DNA binding 3
chr10_+_69925800 0.517 ENSMUST00000182029.1
Ank3
ankyrin 3, epithelial
chr2_-_57113053 0.479 ENSMUST00000112627.1
Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr10_+_80930071 0.467 ENSMUST00000015456.8
Gadd45b
growth arrest and DNA-damage-inducible 45 beta
chr16_+_20097554 0.459 ENSMUST00000023509.3
Klhl24
kelch-like 24
chr15_-_58214882 0.454 ENSMUST00000022986.6
Fbxo32
F-box protein 32
chr17_+_48346465 0.443 ENSMUST00000113237.3
Trem2
triggering receptor expressed on myeloid cells 2
chr15_+_9140527 0.441 ENSMUST00000090380.4
Lmbrd2
LMBR1 domain containing 2
chr1_+_134494628 0.436 ENSMUST00000047978.7
Rabif
RAB interacting factor
chrX_+_135993820 0.424 ENSMUST00000058119.7
Arxes2
adipocyte-related X-chromosome expressed sequence 2
chr11_+_78037959 0.413 ENSMUST00000073660.6
Flot2
flotillin 2
chr17_+_48346401 0.411 ENSMUST00000024791.8
Trem2
triggering receptor expressed on myeloid cells 2
chr13_-_56895737 0.406 ENSMUST00000022023.6
ENSMUST00000109871.1
Trpc7

transient receptor potential cation channel, subfamily C, member 7

chr6_-_118455475 0.392 ENSMUST00000161519.1
ENSMUST00000069292.7
Zfp248

zinc finger protein 248

chr10_-_13552838 0.389 ENSMUST00000105541.1
Pex3
peroxisomal biogenesis factor 3
chr9_-_89092835 0.385 ENSMUST00000167113.1
Trim43b
tripartite motif-containing 43B
chr3_+_51559757 0.379 ENSMUST00000180616.1
5031434O11Rik
RIKEN cDNA 5031434O11 gene
chr10_-_64090241 0.378 ENSMUST00000133588.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr17_+_35823509 0.372 ENSMUST00000173493.1
ENSMUST00000173147.1
ENSMUST00000172846.1
Flot1


flotillin 1


chrX_+_6047453 0.367 ENSMUST00000103007.3
Nudt11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr17_+_35823230 0.362 ENSMUST00000001569.8
ENSMUST00000174080.1
Flot1

flotillin 1

chr7_-_25754701 0.362 ENSMUST00000108401.1
ENSMUST00000043765.7
Hnrnpul1

heterogeneous nuclear ribonucleoprotein U-like 1

chr1_+_137966529 0.344 ENSMUST00000182158.1
A430106G13Rik
RIKEN cDNA A430106G13 gene
chr7_-_19715395 0.338 ENSMUST00000032555.9
ENSMUST00000093552.5
Tomm40

translocase of outer mitochondrial membrane 40 homolog (yeast)

chr13_+_88821472 0.329 ENSMUST00000118731.1
ENSMUST00000081769.6
Edil3

EGF-like repeats and discoidin I-like domains 3

chr14_-_45477856 0.323 ENSMUST00000141424.1
Fermt2
fermitin family homolog 2 (Drosophila)
chrX_+_136741821 0.305 ENSMUST00000089350.4
BC065397
cDNA sequence BC065397
chr10_-_117292863 0.305 ENSMUST00000092162.5
Lyz1
lysozyme 1
chr2_-_132578244 0.294 ENSMUST00000110142.1
Gpcpd1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr3_-_108086590 0.277 ENSMUST00000102638.1
ENSMUST00000102637.1
Ampd2

adenosine monophosphate deaminase 2

chr5_-_137533170 0.266 ENSMUST00000168746.1
ENSMUST00000170293.1
Gnb2

guanine nucleotide binding protein (G protein), beta 2

chr14_+_32166104 0.256 ENSMUST00000164341.1
Ncoa4
nuclear receptor coactivator 4
chr14_+_32165784 0.254 ENSMUST00000111994.3
ENSMUST00000168114.1
ENSMUST00000168034.1
Ncoa4


nuclear receptor coactivator 4


chr3_+_7612702 0.251 ENSMUST00000181286.1
Gm16685
predicted gene, 16685
chrX_-_74428871 0.250 ENSMUST00000143521.1
G6pdx
glucose-6-phosphate dehydrogenase X-linked
chr7_+_3645267 0.245 ENSMUST00000038913.9
Cnot3
CCR4-NOT transcription complex, subunit 3
chr19_+_34290653 0.244 ENSMUST00000025691.5
ENSMUST00000112472.2
Fas

Fas (TNF receptor superfamily member 6)

chr7_+_110777653 0.242 ENSMUST00000148292.1
Ampd3
adenosine monophosphate deaminase 3
chr5_-_92083667 0.240 ENSMUST00000113127.3
G3bp2
GTPase activating protein (SH3 domain) binding protein 2
chr2_-_132578155 0.239 ENSMUST00000110136.1
ENSMUST00000124107.1
ENSMUST00000060955.5
Gpcpd1


glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)


chr2_+_32876114 0.229 ENSMUST00000028135.8
Fam129b
family with sequence similarity 129, member B
chrX_+_153498202 0.221 ENSMUST00000060714.8
Ubqln2
ubiquilin 2
chr2_+_71055731 0.220 ENSMUST00000154704.1
ENSMUST00000135357.1
ENSMUST00000064141.5
ENSMUST00000112159.2
ENSMUST00000102701.3
Dcaf17




DDB1 and CUL4 associated factor 17




chr15_-_88978958 0.214 ENSMUST00000042594.6
ENSMUST00000109368.1
Mlc1

megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human)

chr19_-_8818924 0.210 ENSMUST00000153281.1
Ttc9c
tetratricopeptide repeat domain 9C
chr12_-_111377705 0.209 ENSMUST00000041965.3
Cdc42bpb
CDC42 binding protein kinase beta
chr2_-_32424005 0.207 ENSMUST00000113307.2
Slc25a25
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25
chr16_-_4559720 0.207 ENSMUST00000005862.7
Tfap4
transcription factor AP4
chr10_+_39369750 0.206 ENSMUST00000063091.6
ENSMUST00000099967.3
ENSMUST00000126486.1
Fyn


Fyn proto-oncogene


chr11_+_75732869 0.205 ENSMUST00000067664.3
Ywhae
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr7_-_121074501 0.198 ENSMUST00000047194.2
Igsf6
immunoglobulin superfamily, member 6
chr5_-_147894804 0.193 ENSMUST00000118527.1
ENSMUST00000031655.3
ENSMUST00000138244.1
Slc46a3


solute carrier family 46, member 3


chr18_-_34931993 0.188 ENSMUST00000025218.7
Etf1
eukaryotic translation termination factor 1
chr2_-_129371131 0.185 ENSMUST00000028881.7
Il1b
interleukin 1 beta
chr2_+_155751117 0.181 ENSMUST00000029140.5
ENSMUST00000132608.1
Procr

protein C receptor, endothelial

chr2_-_152831665 0.177 ENSMUST00000156688.1
ENSMUST00000007803.5
Bcl2l1

BCL2-like 1

chr9_-_123717576 0.177 ENSMUST00000026274.7
Lztfl1
leucine zipper transcription factor-like 1
chr2_+_22895482 0.171 ENSMUST00000053729.7
Pdss1
prenyl (solanesyl) diphosphate synthase, subunit 1
chr18_-_52529847 0.166 ENSMUST00000171470.1
Lox
lysyl oxidase
chr18_-_52529692 0.163 ENSMUST00000025409.7
Lox
lysyl oxidase
chr10_-_25297055 0.161 ENSMUST00000177124.1
Akap7
A kinase (PRKA) anchor protein 7
chr5_+_90759299 0.159 ENSMUST00000031318.4
Cxcl5
chemokine (C-X-C motif) ligand 5
chr4_-_36136463 0.158 ENSMUST00000098151.2
Lingo2
leucine rich repeat and Ig domain containing 2
chr3_+_106113229 0.157 ENSMUST00000079132.5
ENSMUST00000139086.1
Chia

chitinase, acidic

chr1_+_60343297 0.156 ENSMUST00000114202.1
ENSMUST00000060608.6
Cyp20a1

cytochrome P450, family 20, subfamily a, polypeptide 1

chr4_-_58911902 0.154 ENSMUST00000134848.1
ENSMUST00000107557.2
ENSMUST00000149301.1
AI314180


expressed sequence AI314180


chr10_-_62651194 0.139 ENSMUST00000020270.4
Ddx50
DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
chr9_+_107975529 0.137 ENSMUST00000035216.4
Uba7
ubiquitin-like modifier activating enzyme 7
chr7_+_103550368 0.135 ENSMUST00000106888.1
Olfr613
olfactory receptor 613
chr8_+_94601928 0.123 ENSMUST00000060389.8
ENSMUST00000121101.1
Rspry1

ring finger and SPRY domain containing 1

chrX_+_94636066 0.121 ENSMUST00000096368.3
Gspt2
G1 to S phase transition 2
chr5_+_30889326 0.116 ENSMUST00000124908.1
Agbl5
ATP/GTP binding protein-like 5
chr3_-_63964659 0.114 ENSMUST00000161659.1
Slc33a1
solute carrier family 33 (acetyl-CoA transporter), member 1
chr5_-_138171216 0.114 ENSMUST00000147920.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr4_+_55350043 0.103 ENSMUST00000030134.8
Rad23b
RAD23b homolog (S. cerevisiae)
chr11_+_106216926 0.102 ENSMUST00000021046.5
Ddx42
DEAD (Asp-Glu-Ala-Asp) box polypeptide 42
chr2_+_172248492 0.098 ENSMUST00000038532.1
Mc3r
melanocortin 3 receptor
chr17_+_35841491 0.098 ENSMUST00000082337.6
Mdc1
mediator of DNA damage checkpoint 1
chr1_-_132707304 0.090 ENSMUST00000043189.7
Nfasc
neurofascin
chr3_-_82876483 0.089 ENSMUST00000048647.7
Rbm46
RNA binding motif protein 46
chr4_-_36056726 0.086 ENSMUST00000108124.3
Lingo2
leucine rich repeat and Ig domain containing 2
chr13_+_51100810 0.086 ENSMUST00000095797.5
Spin1
spindlin 1
chr7_+_6474088 0.077 ENSMUST00000056144.5
Olfr1346
olfactory receptor 1346
chr7_-_100371889 0.070 ENSMUST00000032963.8
Ppme1
protein phosphatase methylesterase 1
chr11_+_6415443 0.068 ENSMUST00000132846.1
Ppia
peptidylprolyl isomerase A
chr8_-_46211284 0.065 ENSMUST00000034049.4
Slc25a4
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4
chr9_-_8134294 0.064 ENSMUST00000037397.6
AK129341
cDNA sequence AK129341
chr5_+_114444266 0.060 ENSMUST00000043760.8
ENSMUST00000112239.2
ENSMUST00000125650.1
Mvk


mevalonate kinase


chr8_-_94601720 0.059 ENSMUST00000034226.6
Fam192a
family with sequence similarity 192, member A
chr1_-_6215292 0.057 ENSMUST00000097832.1
4732440D04Rik
RIKEN cDNA 4732440D04 gene
chr17_+_32284772 0.056 ENSMUST00000181112.1
Gm26549
predicted gene, 26549
chr8_-_41054771 0.055 ENSMUST00000093534.4
Mtus1
mitochondrial tumor suppressor 1
chr19_-_7341792 0.054 ENSMUST00000164205.1
ENSMUST00000165286.1
ENSMUST00000168324.1
ENSMUST00000032557.8
Mark2



MAP/microtubule affinity-regulating kinase 2



chr6_+_83078339 0.026 ENSMUST00000165164.2
ENSMUST00000092614.2
Pcgf1

polycomb group ring finger 1

chr9_+_110419750 0.025 ENSMUST00000035061.6
Ngp
neutrophilic granule protein
chr17_-_35235755 0.022 ENSMUST00000048994.6
Nfkbil1
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor like 1
chrX_+_159459125 0.022 ENSMUST00000043151.5
ENSMUST00000112470.1
ENSMUST00000156172.1
Map7d2


MAP7 domain containing 2


chr2_+_176711933 0.020 ENSMUST00000108983.2
Gm14305
predicted gene 14305
chr4_-_130359915 0.017 ENSMUST00000134159.2
Zcchc17
zinc finger, CCHC domain containing 17
chr16_-_13903085 0.017 ENSMUST00000023361.5
ENSMUST00000115802.1
Pdxdc1

pyridoxal-dependent decarboxylase domain containing 1

chr12_+_105032638 0.009 ENSMUST00000021522.3
Glrx5
glutaredoxin 5 homolog (S. cerevisiae)
chr6_-_38046994 0.009 ENSMUST00000096040.4
Svopl
SV2 related protein homolog (rat)-like
chr3_-_107986408 0.008 ENSMUST00000012348.2
Gstm2
glutathione S-transferase, mu 2
chr3_-_107986360 0.008 ENSMUST00000066530.6
Gstm2
glutathione S-transferase, mu 2
chr16_-_13903051 0.002 ENSMUST00000115803.1
Pdxdc1
pyridoxal-dependent decarboxylase domain containing 1

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 6.2 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.7 3.0 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.5 2.5 GO:0046684 response to pyrethroid(GO:0046684)
0.5 3.5 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.5 1.4 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931) calcium-independent cell-matrix adhesion(GO:0007161) transforming growth factor-beta secretion(GO:0038044)
0.4 4.3 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.4 1.7 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.4 2.0 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.3 0.9 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256) response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
0.3 0.9 GO:0002586 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588) detection of peptidoglycan(GO:0032499)
0.3 1.6 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.2 1.1 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.2 0.8 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.2 0.6 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430)
0.2 1.3 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.2 0.5 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.2 1.8 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 0.5 GO:0017085 response to insecticide(GO:0017085)
0.2 1.2 GO:0005513 detection of calcium ion(GO:0005513)
0.2 0.5 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.2 0.5 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.6 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.1 0.6 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.1 1.0 GO:0006561 proline biosynthetic process(GO:0006561)
0.1 0.4 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.1 1.1 GO:0071420 cellular response to histamine(GO:0071420)
0.1 0.3 GO:0002034 angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998) regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
0.1 0.7 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.1 0.5 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 0.5 GO:0042701 progesterone secretion(GO:0042701)
0.1 0.3 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 0.8 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 1.2 GO:1901898 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.2 GO:0060558 regulation of calcidiol 1-monooxygenase activity(GO:0060558)
0.1 0.5 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 0.8 GO:0019227 neuronal action potential propagation(GO:0019227) detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962) action potential propagation(GO:0098870)
0.1 0.6 GO:0061368 maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.1 0.8 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.5 GO:0032264 IMP salvage(GO:0032264)
0.1 0.2 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.1 0.7 GO:0061470 interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619)
0.1 0.1 GO:2000277 positive regulation of oxidative phosphorylation uncoupler activity(GO:2000277)
0.1 0.4 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.1 0.6 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.4 GO:1901911 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.2 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.1 0.6 GO:0006983 ER overload response(GO:0006983)
0.1 0.2 GO:0070944 neutrophil mediated killing of bacterium(GO:0070944)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.9 GO:0046688 response to copper ion(GO:0046688)
0.0 0.2 GO:0046898 response to cycloheximide(GO:0046898)
0.0 0.4 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 0.2 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.2 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0 1.5 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.2 GO:1903564 regulation of protein localization to cilium(GO:1903564)
0.0 0.2 GO:0032274 gonadotropin secretion(GO:0032274)
0.0 0.2 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.5 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 2.4 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.5 GO:0030903 notochord development(GO:0030903)
0.0 0.2 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:2001269 negative regulation by host of viral transcription(GO:0043922) positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0 5.4 GO:0060271 cilium morphogenesis(GO:0060271)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.1 GO:0035608 protein deglutamylation(GO:0035608)
0.0 0.3 GO:0033622 integrin activation(GO:0033622)
0.0 0.0 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.0 1.2 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.2 GO:0014823 response to activity(GO:0014823)
0.0 0.2 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.7 GO:0008542 visual learning(GO:0008542)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 6.2 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.7 2.9 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.6 3.0 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.5 1.4 GO:0005577 fibrinogen complex(GO:0005577)
0.3 4.3 GO:0043203 axon hillock(GO:0043203)
0.2 0.6 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.2 2.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.2 1.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 1.1 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 1.8 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 1.1 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 0.3 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.5 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 5.9 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 2.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 2.6 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 0.5 GO:0044754 autolysosome(GO:0044754)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.6 GO:0097440 apical dendrite(GO:0097440)
0.0 1.2 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.9 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.4 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 1.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.2 GO:0042641 actomyosin(GO:0042641)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.5 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.7 2.9 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.3 6.2 GO:0051787 misfolded protein binding(GO:0051787)
0.2 5.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.2 1.0 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.2 1.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2 1.4 GO:0045340 mercury ion binding(GO:0045340)
0.2 0.9 GO:0070891 peptidoglycan binding(GO:0042834) lipoteichoic acid binding(GO:0070891)
0.2 0.8 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.2 0.6 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
0.2 1.7 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.2 0.9 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 0.6 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.1 3.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.5 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 2.5 GO:0031402 sodium ion binding(GO:0031402)
0.1 0.6 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 0.3 GO:0003796 lysozyme activity(GO:0003796)
0.1 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.2 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.1 1.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 0.6 GO:0015386 potassium:proton antiporter activity(GO:0015386) potassium ion antiporter activity(GO:0022821)
0.1 0.8 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.5 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.9 GO:0008301 DNA binding, bending(GO:0008301)
0.1 1.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.1 0.5 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 1.1 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 2.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 0.3 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 0.4 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 0.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.3 GO:0015288 porin activity(GO:0015288)
0.0 0.2 GO:0050347 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.0 1.6 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.2 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 1.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0004980 melanocortin receptor activity(GO:0004977) melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 1.8 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.3 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.2 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.6 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 1.1 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 2.9 GO:0044325 ion channel binding(GO:0044325)
0.0 0.1 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 1.5 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.6 GO:0005507 copper ion binding(GO:0005507)
0.0 6.8 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.5 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.3 GO:0005246 calcium channel regulator activity(GO:0005246)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 6.0 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.1 3.5 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 0.5 PID_FOXO_PATHWAY FoxO family signaling
0.0 0.2 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.6 PID_BMP_PATHWAY BMP receptor signaling
0.0 1.3 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 0.6 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 0.6 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 1.1 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.2 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.5 PID_AVB3_INTEGRIN_PATHWAY Integrins in angiogenesis
0.0 0.2 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 0.4 PID_PI3KCI_AKT_PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.6 PID_AP1_PATHWAY AP-1 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.0 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 1.4 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 3.2 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.1 3.5 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 6.2 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 1.1 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.1 0.5 REACTOME_AMYLOIDS Genes involved in Amyloids
0.1 0.4 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 5.2 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 1.3 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 1.2 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.1 1.6 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.1 1.8 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.2 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.8 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.9 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.2 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.5 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.8 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.7 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.6 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.0 0.6 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.4 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.2 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.3 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.8 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes