Motif ID: Cebpb
Z-value: 0.846
Transcription factors associated with Cebpb:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Cebpb | ENSMUSG00000056501.3 | Cebpb |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Cebpb | mm10_v2_chr2_+_167688915_167688973 | 0.57 | 4.8e-06 | Click! |
Top targets:
Showing 1 to 20 of 166 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 99 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 9.7 | GO:1902998 | macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998) |
| 0.1 | 6.3 | GO:0003073 | regulation of systemic arterial blood pressure(GO:0003073) |
| 2.0 | 6.0 | GO:0002586 | positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588) detection of peptidoglycan(GO:0032499) |
| 1.2 | 5.9 | GO:2000255 | negative regulation of male germ cell proliferation(GO:2000255) |
| 0.1 | 4.5 | GO:0030032 | lamellipodium assembly(GO:0030032) |
| 1.3 | 3.9 | GO:0006931 | substrate-dependent cell migration, cell attachment to substrate(GO:0006931) calcium-independent cell-matrix adhesion(GO:0007161) transforming growth factor-beta secretion(GO:0038044) |
| 1.2 | 3.6 | GO:0035790 | platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) |
| 0.7 | 2.9 | GO:1904706 | heme oxidation(GO:0006788) negative regulation of vascular smooth muscle cell proliferation(GO:1904706) |
| 0.1 | 2.9 | GO:0045744 | negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744) |
| 0.0 | 2.9 | GO:0043547 | positive regulation of GTPase activity(GO:0043547) |
| 0.3 | 2.8 | GO:0043615 | astrocyte cell migration(GO:0043615) |
| 0.0 | 2.5 | GO:0035023 | regulation of Rho protein signal transduction(GO:0035023) |
| 0.3 | 2.4 | GO:0070494 | regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) |
| 0.3 | 2.4 | GO:0044539 | long-chain fatty acid import(GO:0044539) |
| 0.0 | 2.4 | GO:0031638 | zymogen activation(GO:0031638) |
| 0.3 | 2.3 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
| 0.1 | 2.2 | GO:0002495 | antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504) |
| 0.3 | 2.1 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
| 0.0 | 2.1 | GO:0070373 | negative regulation of ERK1 and ERK2 cascade(GO:0070373) |
| 0.3 | 2.0 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 35 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 9.7 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) |
| 0.1 | 7.5 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 1.6 | 4.8 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.0 | 3.6 | GO:0005902 | microvillus(GO:0005902) |
| 0.0 | 3.1 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.0 | 2.9 | GO:0005901 | caveola(GO:0005901) |
| 0.1 | 2.7 | GO:0098644 | complex of collagen trimers(GO:0098644) |
| 0.0 | 2.6 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
| 0.2 | 2.4 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.0 | 2.4 | GO:0036126 | sperm flagellum(GO:0036126) |
| 0.1 | 2.2 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.4 | 2.0 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.0 | 2.0 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.6 | 1.8 | GO:0043512 | inhibin A complex(GO:0043512) |
| 0.3 | 1.7 | GO:0098831 | presynaptic active zone cytoplasmic component(GO:0098831) |
| 0.0 | 1.6 | GO:0045111 | intermediate filament cytoskeleton(GO:0045111) |
| 0.2 | 1.5 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
| 0.5 | 1.4 | GO:0032311 | angiogenin-PRI complex(GO:0032311) |
| 0.1 | 1.4 | GO:0043203 | axon hillock(GO:0043203) |
| 0.0 | 1.4 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 70 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 9.7 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 2.0 | 8.0 | GO:0070891 | lipoteichoic acid binding(GO:0070891) |
| 0.2 | 6.3 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 1.5 | 5.9 | GO:0004667 | prostaglandin-D synthase activity(GO:0004667) |
| 0.1 | 4.7 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.6 | 3.9 | GO:0045340 | mercury ion binding(GO:0045340) |
| 0.1 | 3.7 | GO:0005518 | collagen binding(GO:0005518) |
| 0.7 | 3.6 | GO:0038085 | vascular endothelial growth factor binding(GO:0038085) |
| 0.7 | 2.9 | GO:0004392 | heme oxygenase (decyclizing) activity(GO:0004392) |
| 0.0 | 2.9 | GO:0005085 | guanyl-nucleotide exchange factor activity(GO:0005085) |
| 0.0 | 2.9 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.1 | 2.8 | GO:0048020 | CCR chemokine receptor binding(GO:0048020) |
| 0.8 | 2.4 | GO:0043758 | acetate-CoA ligase (ADP-forming) activity(GO:0043758) |
| 0.6 | 2.4 | GO:0005008 | hepatocyte growth factor-activated receptor activity(GO:0005008) |
| 0.1 | 2.4 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.1 | 2.3 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.0 | 2.1 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.5 | 2.0 | GO:0004720 | protein-lysine 6-oxidase activity(GO:0004720) |
| 0.3 | 2.0 | GO:0016936 | galactoside binding(GO:0016936) |
| 0.5 | 1.9 | GO:0004735 | pyrroline-5-carboxylate reductase activity(GO:0004735) |
Gene overrepresentation in C2:CP category:
Showing 1 to 20 of 25 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 7.4 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 6.5 | PID_MYC_REPRESS_PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.2 | 5.6 | PID_FRA_PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.2 | 3.9 | PID_INTEGRIN5_PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.1 | 3.6 | PID_PDGFRA_PATHWAY | PDGFR-alpha signaling pathway |
| 0.1 | 3.3 | PID_IL12_2PATHWAY | IL12-mediated signaling events |
| 0.1 | 2.9 | PID_RAS_PATHWAY | Regulation of Ras family activation |
| 0.1 | 2.4 | PID_SYNDECAN_1_PATHWAY | Syndecan-1-mediated signaling events |
| 0.0 | 2.0 | PID_BETA_CATENIN_NUC_PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.1 | 1.9 | PID_EPHA2_FWD_PATHWAY | EPHA2 forward signaling |
| 0.1 | 1.8 | PID_ALK1_PATHWAY | ALK1 signaling events |
| 0.0 | 1.8 | PID_ATF2_PATHWAY | ATF-2 transcription factor network |
| 0.1 | 1.7 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
| 0.1 | 1.6 | PID_EPHA_FWDPATHWAY | EPHA forward signaling |
| 0.0 | 1.4 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 1.3 | PID_HIF1_TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.0 | 1.0 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 1.0 | SIG_BCR_SIGNALING_PATHWAY | Members of the BCR signaling pathway |
| 0.0 | 1.0 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
| 0.0 | 0.9 | PID_INTEGRIN3_PATHWAY | Beta3 integrin cell surface interactions |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 30 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 12.5 | REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.1 | 6.6 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | Genes involved in NRAGE signals death through JNK |
| 0.2 | 6.0 | REACTOME_OTHER_SEMAPHORIN_INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.3 | 5.4 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.2 | 4.5 | REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.1 | 4.5 | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.0 | 4.1 | REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.0 | 3.6 | REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION | Genes involved in Downstream signal transduction |
| 0.2 | 3.5 | REACTOME_METABOLISM_OF_PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.1 | 3.3 | REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.1 | 2.9 | REACTOME_INTEGRIN_ALPHAIIB_BETA3_SIGNALING | Genes involved in Integrin alphaIIb beta3 signaling |
| 0.1 | 2.8 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.2 | 2.7 | REACTOME_CS_DS_DEGRADATION | Genes involved in CS/DS degradation |
| 0.2 | 2.6 | REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS | Genes involved in p130Cas linkage to MAPK signaling for integrins |
| 0.1 | 2.4 | REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle |
| 0.1 | 2.4 | REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING | Genes involved in Sema4D in semaphorin signaling |
| 0.0 | 2.1 | REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.5 | 1.8 | REACTOME_GLYCOPROTEIN_HORMONES | Genes involved in Glycoprotein hormones |
| 0.2 | 1.7 | REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
| 0.2 | 1.7 | REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 | Genes involved in IKK complex recruitment mediated by RIP1 |
