Motif ID: Cebpd

Z-value: 0.421


Transcription factors associated with Cebpd:

Gene SymbolEntrez IDGene Name
Cebpd ENSMUSG00000071637.4 Cebpd



Activity profile for motif Cebpd.

activity profile for motif Cebpd


Sorted Z-values histogram for motif Cebpd

Sorted Z-values for motif Cebpd



Network of associatons between targets according to the STRING database.



First level regulatory network of Cebpd

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_17463749 2.114 ENSMUST00000115443.1
Met
met proto-oncogene
chr19_-_57239310 2.033 ENSMUST00000111559.1
Ablim1
actin-binding LIM protein 1
chr1_-_140183404 1.824 ENSMUST00000066859.6
ENSMUST00000111976.2
Cfh

complement component factor h

chr1_-_71653162 1.679 ENSMUST00000055226.6
Fn1
fibronectin 1
chr11_-_75422586 1.321 ENSMUST00000138661.1
ENSMUST00000000769.7
Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr9_-_103230415 1.319 ENSMUST00000035158.9
Trf
transferrin
chr18_-_52529847 1.292 ENSMUST00000171470.1
Lox
lysyl oxidase
chr1_-_140183283 1.278 ENSMUST00000111977.1
Cfh
complement component factor h
chr17_+_48346465 1.204 ENSMUST00000113237.3
Trem2
triggering receptor expressed on myeloid cells 2
chr18_-_52529692 1.195 ENSMUST00000025409.7
Lox
lysyl oxidase
chr17_+_48346401 1.187 ENSMUST00000024791.8
Trem2
triggering receptor expressed on myeloid cells 2
chr13_+_16011851 1.065 ENSMUST00000042603.6
Inhba
inhibin beta-A
chr14_-_18893376 0.928 ENSMUST00000151926.1
Ube2e2
ubiquitin-conjugating enzyme E2E 2
chr11_-_75422524 0.825 ENSMUST00000125982.1
ENSMUST00000137103.1
Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr15_-_101850778 0.740 ENSMUST00000023790.3
Krt1
keratin 1
chr2_+_155751117 0.710 ENSMUST00000029140.5
ENSMUST00000132608.1
Procr

protein C receptor, endothelial

chr3_+_19957037 0.637 ENSMUST00000091309.5
ENSMUST00000108329.1
ENSMUST00000003714.6
Cp


ceruloplasmin


chr13_+_63014934 0.588 ENSMUST00000091560.4
2010111I01Rik
RIKEN cDNA 2010111I01 gene
chrX_-_162565514 0.550 ENSMUST00000154424.1
Reps2
RALBP1 associated Eps domain containing protein 2
chr14_-_18893623 0.549 ENSMUST00000177259.1
Ube2e2
ubiquitin-conjugating enzyme E2E 2
chr17_-_85090204 0.548 ENSMUST00000072406.3
ENSMUST00000171795.1
Prepl

prolyl endopeptidase-like

chr8_-_33929798 0.520 ENSMUST00000033995.7
ENSMUST00000033994.8
ENSMUST00000053251.5
Rbpms


RNA binding protein gene with multiple splicing


chr7_+_30751471 0.449 ENSMUST00000182229.1
ENSMUST00000182227.1
ENSMUST00000080518.6
ENSMUST00000182721.1
Sbsn



suprabasin



chr9_-_103230262 0.432 ENSMUST00000165296.1
ENSMUST00000112645.1
ENSMUST00000166836.1
Trf

Gm20425
transferrin

predicted gene 20425
chr4_-_130359915 0.413 ENSMUST00000134159.2
Zcchc17
zinc finger, CCHC domain containing 17
chr13_-_117025505 0.398 ENSMUST00000022239.6
Parp8
poly (ADP-ribose) polymerase family, member 8
chr8_+_94037198 0.386 ENSMUST00000109556.2
ENSMUST00000093301.2
ENSMUST00000060632.7
Ogfod1


2-oxoglutarate and iron-dependent oxygenase domain containing 1


chr7_-_127273919 0.386 ENSMUST00000082428.3
Sephs2
selenophosphate synthetase 2
chr7_+_24507006 0.376 ENSMUST00000176880.1
Zfp428
zinc finger protein 428
chrX_-_134600976 0.361 ENSMUST00000033621.6
Gla
galactosidase, alpha
chr4_+_152039315 0.346 ENSMUST00000084116.6
ENSMUST00000105663.1
ENSMUST00000103197.3
Nol9


nucleolar protein 9


chr7_-_45830776 0.311 ENSMUST00000107723.2
ENSMUST00000131384.1
Grwd1

glutamate-rich WD repeat containing 1

chr2_-_57113053 0.288 ENSMUST00000112627.1
Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr13_+_63015167 0.281 ENSMUST00000021911.8
2010111I01Rik
RIKEN cDNA 2010111I01 gene
chr11_+_6415443 0.277 ENSMUST00000132846.1
Ppia
peptidylprolyl isomerase A
chr5_-_147894804 0.249 ENSMUST00000118527.1
ENSMUST00000031655.3
ENSMUST00000138244.1
Slc46a3


solute carrier family 46, member 3


chr19_-_8819314 0.243 ENSMUST00000096751.4
Ttc9c
tetratricopeptide repeat domain 9C
chr2_-_129371131 0.237 ENSMUST00000028881.7
Il1b
interleukin 1 beta
chr19_+_8819401 0.228 ENSMUST00000096753.3
Hnrnpul2
heterogeneous nuclear ribonucleoprotein U-like 2
chr19_-_8819278 0.218 ENSMUST00000088092.5
Ttc9c
tetratricopeptide repeat domain 9C
chr2_-_3512746 0.215 ENSMUST00000027961.5
ENSMUST00000056700.7
Hspa14
Hspa14
heat shock protein 14
heat shock protein 14
chrX_+_94234594 0.190 ENSMUST00000153900.1
Klhl15
kelch-like 15
chr5_+_115279666 0.189 ENSMUST00000040421.4
Coq5
coenzyme Q5 homolog, methyltransferase (yeast)
chr5_+_63812447 0.172 ENSMUST00000081747.3
0610040J01Rik
RIKEN cDNA 0610040J01 gene
chr6_-_87809757 0.164 ENSMUST00000032134.7
Rab43
RAB43, member RAS oncogene family
chr14_-_45477856 0.161 ENSMUST00000141424.1
Fermt2
fermitin family homolog 2 (Drosophila)
chr8_-_46211284 0.149 ENSMUST00000034049.4
Slc25a4
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4
chr5_-_145140238 0.133 ENSMUST00000031627.8
Pdap1
PDGFA associated protein 1
chr12_+_37241633 0.126 ENSMUST00000049874.7
Agmo
alkylglycerol monooxygenase
chr19_-_8818924 0.120 ENSMUST00000153281.1
Ttc9c
tetratricopeptide repeat domain 9C
chr2_+_32876114 0.101 ENSMUST00000028135.8
Fam129b
family with sequence similarity 129, member B
chr17_+_85090647 0.095 ENSMUST00000095188.5
Camkmt
calmodulin-lysine N-methyltransferase
chr12_+_86421628 0.092 ENSMUST00000110203.1
ENSMUST00000110204.2
Esrrb

estrogen related receptor, beta

chr2_+_3513035 0.091 ENSMUST00000036350.2
Cdnf
cerebral dopamine neurotrophic factor
chr4_+_55350043 0.084 ENSMUST00000030134.8
Rad23b
RAD23b homolog (S. cerevisiae)
chr11_-_87086752 0.079 ENSMUST00000020801.7
Smg8
smg-8 homolog, nonsense mediated mRNA decay factor (C. elegans)
chr18_+_20944607 0.068 ENSMUST00000050004.1
Rnf125
ring finger protein 125
chr1_-_162898665 0.049 ENSMUST00000111510.1
ENSMUST00000045902.6
Fmo2

flavin containing monooxygenase 2

chr17_-_56121946 0.010 ENSMUST00000041357.7
Lrg1
leucine-rich alpha-2-glycoprotein 1
chr11_-_106216318 0.010 ENSMUST00000002043.3
Ccdc47
coiled-coil domain containing 47

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0002586 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588) detection of peptidoglycan(GO:0032499)
0.6 1.7 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931) calcium-independent cell-matrix adhesion(GO:0007161) transforming growth factor-beta secretion(GO:0038044)
0.5 3.1 GO:0045919 complement activation, alternative pathway(GO:0006957) positive regulation of cytolysis(GO:0045919)
0.3 2.1 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.3 2.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 2.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.2 1.8 GO:0098707 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.2 1.1 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.2 1.5 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.3 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.1 0.7 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.4 GO:0001887 selenium compound metabolic process(GO:0001887) selenocysteine metabolic process(GO:0016259)
0.1 0.2 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092) positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.1 0.3 GO:0051866 general adaptation syndrome(GO:0051866)
0.1 0.2 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.1 GO:0015866 ADP transport(GO:0015866)
0.0 0.4 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.4 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.6 GO:0046688 response to copper ion(GO:0046688)
0.0 0.2 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.1 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0 0.9 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.5 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.1 GO:0090282 trophectodermal cellular morphogenesis(GO:0001831) positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931) positive regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0090282)
0.0 0.7 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 0.3 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.1 GO:0032274 gonadotropin secretion(GO:0032274)
0.0 1.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.3 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.5 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.0 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 0.2 GO:0006744 ubiquinone biosynthetic process(GO:0006744)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0005577 fibrinogen complex(GO:0005577)
0.4 1.1 GO:0043512 inhibin A complex(GO:0043512)
0.2 1.8 GO:0097433 dense body(GO:0097433)
0.2 2.1 GO:0043203 axon hillock(GO:0043203)
0.1 0.7 GO:0001533 cornified envelope(GO:0001533)
0.0 3.7 GO:0072562 blood microparticle(GO:0072562)
0.0 2.5 GO:0005581 collagen trimer(GO:0005581)
0.0 1.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 2.2 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.5 GO:0005685 U1 snRNP(GO:0005685)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.1 GO:0001851 complement component C3b binding(GO:0001851)
0.6 2.5 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.6 2.4 GO:0070891 peptidoglycan binding(GO:0042834) lipoteichoic acid binding(GO:0070891)
0.5 2.1 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.3 1.7 GO:0045340 mercury ion binding(GO:0045340)
0.3 1.8 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.2 1.5 GO:0042296 ISG15 transferase activity(GO:0042296)
0.2 1.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.6 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.5 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.4 GO:0016936 galactoside binding(GO:0016936)
0.0 0.3 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0 2.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.4 GO:0031543 peptidyl-proline dioxygenase activity(GO:0031543)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.1 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 2.1 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 5.0 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.1 PID_ALK1_PATHWAY ALK1 signaling events
0.0 0.2 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.1 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.3 1.1 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.1 2.4 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.0 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 2.0 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.1 2.1 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.3 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.6 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.4 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism