Motif ID: Cebpe
Z-value: 0.993
Transcription factors associated with Cebpe:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Cebpe | ENSMUSG00000052435.6 | Cebpe |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.1 | 12.4 | GO:0046122 | purine deoxyribonucleoside metabolic process(GO:0046122) |
| 2.4 | 11.8 | GO:0015671 | oxygen transport(GO:0015671) |
| 2.3 | 6.8 | GO:0002191 | cap-dependent translational initiation(GO:0002191) |
| 2.1 | 14.4 | GO:2001199 | negative regulation of dendritic cell differentiation(GO:2001199) |
| 1.3 | 6.3 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
| 1.2 | 3.5 | GO:0043988 | histone H3-S28 phosphorylation(GO:0043988) |
| 0.8 | 2.5 | GO:2000620 | positive regulation of histone H4-K16 acetylation(GO:2000620) |
| 0.8 | 3.3 | GO:1904778 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
| 0.8 | 0.8 | GO:0007113 | endomitotic cell cycle(GO:0007113) |
| 0.7 | 2.9 | GO:0002337 | B-1a B cell differentiation(GO:0002337) |
| 0.7 | 2.1 | GO:0031204 | posttranslational protein targeting to membrane, translocation(GO:0031204) |
| 0.7 | 2.1 | GO:2000373 | regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373) |
| 0.7 | 2.7 | GO:0019287 | isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) |
| 0.7 | 1.4 | GO:0021502 | neural fold elevation formation(GO:0021502) |
| 0.6 | 2.6 | GO:0015889 | cobalamin transport(GO:0015889) |
| 0.6 | 1.9 | GO:0048687 | positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) |
| 0.6 | 2.4 | GO:0035609 | C-terminal protein deglutamylation(GO:0035609) |
| 0.5 | 1.6 | GO:0051105 | regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106) |
| 0.5 | 2.6 | GO:0033499 | galactose catabolic process via UDP-galactose(GO:0033499) |
| 0.5 | 1.5 | GO:0030200 | heparan sulfate proteoglycan catabolic process(GO:0030200) |
| 0.5 | 1.4 | GO:0097402 | neuroblast migration(GO:0097402) |
| 0.5 | 1.4 | GO:0061300 | cerebellum vasculature development(GO:0061300) |
| 0.5 | 3.3 | GO:0016102 | retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102) |
| 0.5 | 1.4 | GO:0045410 | positive regulation of interleukin-6 biosynthetic process(GO:0045410) |
| 0.4 | 3.6 | GO:0010587 | miRNA catabolic process(GO:0010587) |
| 0.4 | 1.3 | GO:1904347 | intestine smooth muscle contraction(GO:0014827) regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) regulation of small intestine smooth muscle contraction(GO:1904347) small intestine smooth muscle contraction(GO:1990770) |
| 0.4 | 1.7 | GO:0045617 | negative regulation of keratinocyte differentiation(GO:0045617) |
| 0.4 | 1.3 | GO:1902915 | negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915) |
| 0.4 | 1.3 | GO:2000659 | regulation of interleukin-1-mediated signaling pathway(GO:2000659) |
| 0.4 | 1.3 | GO:0002946 | tRNA C5-cytosine methylation(GO:0002946) |
| 0.4 | 1.6 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
| 0.4 | 1.2 | GO:0046381 | CMP-N-acetylneuraminate metabolic process(GO:0046381) |
| 0.4 | 2.4 | GO:0055118 | negative regulation of cardiac muscle contraction(GO:0055118) |
| 0.4 | 1.2 | GO:1901856 | negative regulation of cellular respiration(GO:1901856) |
| 0.4 | 4.7 | GO:2001269 | positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269) |
| 0.4 | 1.2 | GO:0001978 | regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) |
| 0.4 | 1.5 | GO:0032382 | positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373) |
| 0.4 | 1.1 | GO:0030862 | neuroblast division in subventricular zone(GO:0021849) positive regulation of polarized epithelial cell differentiation(GO:0030862) |
| 0.4 | 0.8 | GO:2000338 | chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338) |
| 0.4 | 2.2 | GO:0071883 | activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) |
| 0.4 | 2.2 | GO:0006287 | base-excision repair, gap-filling(GO:0006287) |
| 0.4 | 2.1 | GO:1903715 | regulation of aerobic respiration(GO:1903715) |
| 0.4 | 1.8 | GO:0010637 | negative regulation of mitochondrial fusion(GO:0010637) |
| 0.3 | 1.4 | GO:0046947 | hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947) |
| 0.3 | 2.7 | GO:0085020 | protein K6-linked ubiquitination(GO:0085020) |
| 0.3 | 1.0 | GO:1901228 | positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228) |
| 0.3 | 1.7 | GO:0032899 | regulation of neurotrophin production(GO:0032899) positive regulation of neurotrophin production(GO:0032901) |
| 0.3 | 4.9 | GO:0070986 | left/right axis specification(GO:0070986) |
| 0.3 | 3.6 | GO:2001214 | positive regulation of vasculogenesis(GO:2001214) |
| 0.3 | 2.9 | GO:0070874 | negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874) |
| 0.3 | 1.9 | GO:0006363 | termination of RNA polymerase I transcription(GO:0006363) |
| 0.3 | 2.8 | GO:0046459 | short-chain fatty acid metabolic process(GO:0046459) |
| 0.3 | 4.7 | GO:0042407 | cristae formation(GO:0042407) |
| 0.3 | 1.6 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) |
| 0.3 | 0.9 | GO:0007228 | positive regulation of hh target transcription factor activity(GO:0007228) |
| 0.3 | 1.7 | GO:0021965 | spinal cord ventral commissure morphogenesis(GO:0021965) |
| 0.3 | 2.3 | GO:0015670 | carbon dioxide transport(GO:0015670) |
| 0.3 | 1.1 | GO:0050904 | diapedesis(GO:0050904) |
| 0.3 | 1.4 | GO:0010792 | DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) |
| 0.3 | 0.8 | GO:0000448 | cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448) |
| 0.3 | 1.3 | GO:0039536 | negative regulation of RIG-I signaling pathway(GO:0039536) |
| 0.3 | 1.8 | GO:0045078 | positive regulation of interferon-gamma biosynthetic process(GO:0045078) |
| 0.3 | 1.0 | GO:0051866 | general adaptation syndrome(GO:0051866) |
| 0.3 | 1.3 | GO:0072717 | cellular response to actinomycin D(GO:0072717) |
| 0.3 | 3.1 | GO:2000254 | regulation of male germ cell proliferation(GO:2000254) |
| 0.3 | 0.8 | GO:0009106 | lipoate metabolic process(GO:0009106) |
| 0.2 | 0.7 | GO:0006553 | lysine metabolic process(GO:0006553) |
| 0.2 | 0.7 | GO:0000715 | nucleotide-excision repair, DNA damage recognition(GO:0000715) |
| 0.2 | 0.5 | GO:1902174 | positive regulation of keratinocyte apoptotic process(GO:1902174) |
| 0.2 | 0.9 | GO:0001887 | selenium compound metabolic process(GO:0001887) selenocysteine metabolic process(GO:0016259) |
| 0.2 | 0.7 | GO:0019046 | release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382) |
| 0.2 | 6.9 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.2 | 1.3 | GO:0016078 | tRNA catabolic process(GO:0016078) |
| 0.2 | 1.1 | GO:1900186 | negative regulation of clathrin-mediated endocytosis(GO:1900186) |
| 0.2 | 0.7 | GO:0019659 | fermentation(GO:0006113) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661) |
| 0.2 | 1.3 | GO:0034587 | piRNA metabolic process(GO:0034587) |
| 0.2 | 1.1 | GO:0033140 | negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140) |
| 0.2 | 0.4 | GO:0042726 | flavin-containing compound metabolic process(GO:0042726) |
| 0.2 | 0.4 | GO:0030277 | maintenance of gastrointestinal epithelium(GO:0030277) |
| 0.2 | 0.8 | GO:0060729 | intestinal epithelial structure maintenance(GO:0060729) |
| 0.2 | 0.4 | GO:0000480 | endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480) |
| 0.2 | 1.2 | GO:0034080 | CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
| 0.2 | 3.3 | GO:0007100 | mitotic centrosome separation(GO:0007100) |
| 0.2 | 1.6 | GO:0050957 | equilibrioception(GO:0050957) |
| 0.2 | 0.9 | GO:0034421 | post-translational protein acetylation(GO:0034421) |
| 0.2 | 0.7 | GO:0030647 | polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598) |
| 0.2 | 1.7 | GO:0061635 | regulation of protein complex stability(GO:0061635) |
| 0.2 | 3.0 | GO:0009263 | deoxyribonucleotide biosynthetic process(GO:0009263) |
| 0.2 | 1.3 | GO:0014807 | regulation of somitogenesis(GO:0014807) |
| 0.2 | 1.3 | GO:0002862 | negative regulation of inflammatory response to antigenic stimulus(GO:0002862) protein oxidation(GO:0018158) |
| 0.2 | 0.7 | GO:0035606 | peptidyl-cysteine S-trans-nitrosylation(GO:0035606) |
| 0.2 | 1.0 | GO:0051461 | corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461) |
| 0.2 | 1.7 | GO:0071763 | nuclear membrane organization(GO:0071763) |
| 0.2 | 1.0 | GO:0043029 | T cell homeostasis(GO:0043029) |
| 0.2 | 0.6 | GO:0097211 | response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211) |
| 0.2 | 1.1 | GO:0019262 | N-acetylneuraminate catabolic process(GO:0019262) |
| 0.2 | 0.8 | GO:0060467 | negative regulation of fertilization(GO:0060467) |
| 0.2 | 0.8 | GO:0052695 | cellular glucuronidation(GO:0052695) |
| 0.2 | 1.7 | GO:0060539 | diaphragm development(GO:0060539) |
| 0.1 | 0.4 | GO:2000812 | response to rapamycin(GO:1901355) regulation of barbed-end actin filament capping(GO:2000812) |
| 0.1 | 0.3 | GO:0035694 | mitochondrial protein catabolic process(GO:0035694) |
| 0.1 | 0.7 | GO:0072675 | osteoclast fusion(GO:0072675) |
| 0.1 | 0.9 | GO:1902373 | negative regulation of mRNA catabolic process(GO:1902373) |
| 0.1 | 0.1 | GO:0002925 | positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925) |
| 0.1 | 0.9 | GO:0032196 | regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) transposition(GO:0032196) |
| 0.1 | 0.7 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
| 0.1 | 2.2 | GO:0051451 | myoblast migration(GO:0051451) |
| 0.1 | 0.5 | GO:0060155 | platelet dense granule organization(GO:0060155) |
| 0.1 | 0.5 | GO:1901491 | negative regulation of lymphangiogenesis(GO:1901491) |
| 0.1 | 1.6 | GO:1904263 | positive regulation of TORC1 signaling(GO:1904263) |
| 0.1 | 0.7 | GO:0045578 | negative regulation of B cell differentiation(GO:0045578) |
| 0.1 | 0.4 | GO:0006244 | pyrimidine nucleotide catabolic process(GO:0006244) pyrimidine deoxyribonucleotide catabolic process(GO:0009223) |
| 0.1 | 0.4 | GO:0048254 | snoRNA localization(GO:0048254) |
| 0.1 | 0.4 | GO:0070973 | protein localization to endoplasmic reticulum exit site(GO:0070973) |
| 0.1 | 0.5 | GO:0046294 | formaldehyde catabolic process(GO:0046294) |
| 0.1 | 0.9 | GO:0006451 | selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451) |
| 0.1 | 3.6 | GO:0000460 | maturation of 5.8S rRNA(GO:0000460) |
| 0.1 | 2.4 | GO:0035414 | negative regulation of catenin import into nucleus(GO:0035414) |
| 0.1 | 0.7 | GO:0042178 | xenobiotic catabolic process(GO:0042178) |
| 0.1 | 1.1 | GO:1902416 | positive regulation of mRNA binding(GO:1902416) |
| 0.1 | 0.7 | GO:0009136 | ADP biosynthetic process(GO:0006172) nucleoside diphosphate biosynthetic process(GO:0009133) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188) dATP metabolic process(GO:0046060) |
| 0.1 | 0.4 | GO:0033566 | gamma-tubulin complex localization(GO:0033566) |
| 0.1 | 0.2 | GO:0042663 | regulation of endodermal cell fate specification(GO:0042663) |
| 0.1 | 0.5 | GO:0060830 | ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) |
| 0.1 | 0.6 | GO:1902732 | positive regulation of chondrocyte proliferation(GO:1902732) |
| 0.1 | 4.2 | GO:0036075 | endochondral ossification(GO:0001958) replacement ossification(GO:0036075) |
| 0.1 | 0.3 | GO:0014063 | negative regulation of serotonin secretion(GO:0014063) |
| 0.1 | 0.7 | GO:1905244 | regulation of modification of synaptic structure(GO:1905244) |
| 0.1 | 2.6 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.1 | 1.1 | GO:0000722 | telomere maintenance via recombination(GO:0000722) |
| 0.1 | 0.7 | GO:0071557 | histone H3-K27 demethylation(GO:0071557) |
| 0.1 | 0.4 | GO:0034239 | regulation of macrophage fusion(GO:0034239) |
| 0.1 | 0.3 | GO:0006931 | substrate-dependent cell migration, cell attachment to substrate(GO:0006931) |
| 0.1 | 0.6 | GO:0090070 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
| 0.1 | 0.3 | GO:2000435 | regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435) |
| 0.1 | 0.4 | GO:0061743 | motor learning(GO:0061743) |
| 0.1 | 0.7 | GO:0036444 | calcium ion transmembrane import into mitochondrion(GO:0036444) |
| 0.1 | 0.2 | GO:0060971 | embryonic heart tube left/right pattern formation(GO:0060971) |
| 0.1 | 0.7 | GO:0044806 | G-quadruplex DNA unwinding(GO:0044806) |
| 0.1 | 2.0 | GO:0070286 | axonemal dynein complex assembly(GO:0070286) |
| 0.1 | 1.3 | GO:0048664 | neuron fate determination(GO:0048664) |
| 0.1 | 1.0 | GO:2000643 | positive regulation of early endosome to late endosome transport(GO:2000643) |
| 0.1 | 1.7 | GO:0045830 | positive regulation of isotype switching(GO:0045830) |
| 0.1 | 3.6 | GO:0001947 | heart looping(GO:0001947) |
| 0.1 | 1.5 | GO:0050832 | defense response to fungus(GO:0050832) |
| 0.1 | 0.8 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 0.1 | 0.5 | GO:0033632 | regulation of cell-cell adhesion mediated by integrin(GO:0033632) |
| 0.1 | 3.9 | GO:0030490 | maturation of SSU-rRNA(GO:0030490) |
| 0.1 | 0.4 | GO:1903237 | negative regulation of leukocyte tethering or rolling(GO:1903237) |
| 0.1 | 1.4 | GO:0044872 | lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872) |
| 0.1 | 0.4 | GO:0070269 | pyroptosis(GO:0070269) |
| 0.1 | 9.3 | GO:0007052 | mitotic spindle organization(GO:0007052) |
| 0.1 | 0.3 | GO:0019255 | glucose 1-phosphate metabolic process(GO:0019255) |
| 0.1 | 0.6 | GO:0043922 | negative regulation by host of viral transcription(GO:0043922) |
| 0.1 | 0.5 | GO:0009249 | protein lipoylation(GO:0009249) |
| 0.1 | 2.5 | GO:0000578 | embryonic axis specification(GO:0000578) |
| 0.1 | 2.4 | GO:1903077 | negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376) |
| 0.1 | 3.2 | GO:0042462 | eye photoreceptor cell development(GO:0042462) |
| 0.1 | 1.2 | GO:0051292 | nuclear pore complex assembly(GO:0051292) |
| 0.1 | 0.6 | GO:0006729 | tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146) |
| 0.1 | 0.5 | GO:1902018 | negative regulation of cilium assembly(GO:1902018) |
| 0.1 | 1.5 | GO:0045662 | negative regulation of myoblast differentiation(GO:0045662) |
| 0.1 | 1.0 | GO:0038166 | angiotensin-activated signaling pathway(GO:0038166) |
| 0.1 | 0.8 | GO:0006968 | cellular defense response(GO:0006968) |
| 0.1 | 0.5 | GO:0019348 | dolichol metabolic process(GO:0019348) |
| 0.1 | 0.2 | GO:0036233 | glycine import(GO:0036233) |
| 0.1 | 0.3 | GO:0015842 | aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) |
| 0.1 | 0.3 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
| 0.1 | 0.3 | GO:0035617 | stress granule disassembly(GO:0035617) |
| 0.1 | 0.1 | GO:0006990 | positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) |
| 0.1 | 0.6 | GO:0010988 | regulation of low-density lipoprotein particle clearance(GO:0010988) |
| 0.1 | 1.4 | GO:0043087 | regulation of GTPase activity(GO:0043087) |
| 0.1 | 0.3 | GO:0061009 | common bile duct development(GO:0061009) |
| 0.1 | 1.1 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
| 0.1 | 0.3 | GO:0006788 | heme oxidation(GO:0006788) |
| 0.1 | 0.7 | GO:0007250 | activation of NF-kappaB-inducing kinase activity(GO:0007250) |
| 0.1 | 0.5 | GO:0031145 | anaphase-promoting complex-dependent catabolic process(GO:0031145) |
| 0.1 | 0.2 | GO:0014835 | myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) |
| 0.1 | 1.2 | GO:0044381 | glucose import in response to insulin stimulus(GO:0044381) |
| 0.1 | 0.2 | GO:0097167 | circadian regulation of translation(GO:0097167) |
| 0.1 | 0.6 | GO:0000920 | cell separation after cytokinesis(GO:0000920) |
| 0.1 | 3.5 | GO:0045454 | cell redox homeostasis(GO:0045454) |
| 0.1 | 0.4 | GO:0045176 | apical protein localization(GO:0045176) |
| 0.1 | 0.2 | GO:0009414 | response to water deprivation(GO:0009414) |
| 0.1 | 1.0 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663) |
| 0.1 | 0.2 | GO:1900220 | semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220) |
| 0.1 | 0.2 | GO:0035720 | intraciliary anterograde transport(GO:0035720) |
| 0.1 | 0.3 | GO:0034379 | very-low-density lipoprotein particle assembly(GO:0034379) |
| 0.1 | 0.9 | GO:0046069 | cGMP catabolic process(GO:0046069) |
| 0.1 | 0.2 | GO:0042373 | vitamin K metabolic process(GO:0042373) |
| 0.1 | 0.4 | GO:0010566 | regulation of ketone biosynthetic process(GO:0010566) |
| 0.1 | 0.5 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 0.1 | 0.4 | GO:0006983 | ER overload response(GO:0006983) |
| 0.1 | 0.3 | GO:0060576 | intestinal epithelial cell development(GO:0060576) |
| 0.1 | 0.5 | GO:1904153 | negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153) |
| 0.1 | 0.6 | GO:0045899 | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899) |
| 0.1 | 1.1 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
| 0.1 | 0.4 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
| 0.1 | 0.6 | GO:0035562 | negative regulation of chromatin binding(GO:0035562) |
| 0.1 | 0.4 | GO:1902510 | negative regulation of nuclease activity(GO:0032074) negative regulation of execution phase of apoptosis(GO:1900118) regulation of apoptotic DNA fragmentation(GO:1902510) |
| 0.1 | 0.3 | GO:0008635 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635) |
| 0.1 | 2.0 | GO:0006270 | DNA replication initiation(GO:0006270) |
| 0.0 | 0.5 | GO:0010972 | negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) |
| 0.0 | 1.0 | GO:0060009 | Sertoli cell development(GO:0060009) |
| 0.0 | 0.5 | GO:0048733 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) sebaceous gland development(GO:0048733) |
| 0.0 | 1.7 | GO:0042775 | mitochondrial ATP synthesis coupled electron transport(GO:0042775) |
| 0.0 | 0.7 | GO:0097066 | response to thyroid hormone(GO:0097066) |
| 0.0 | 4.6 | GO:0006342 | chromatin silencing(GO:0006342) |
| 0.0 | 0.4 | GO:1900194 | negative regulation of oocyte maturation(GO:1900194) |
| 0.0 | 0.4 | GO:0071802 | negative regulation of podosome assembly(GO:0071802) |
| 0.0 | 0.9 | GO:0021511 | spinal cord patterning(GO:0021511) |
| 0.0 | 0.7 | GO:0035337 | fatty-acyl-CoA metabolic process(GO:0035337) |
| 0.0 | 0.3 | GO:0045583 | regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585) |
| 0.0 | 0.5 | GO:0051490 | negative regulation of filopodium assembly(GO:0051490) |
| 0.0 | 0.1 | GO:0036509 | trimming of terminal mannose on B branch(GO:0036509) |
| 0.0 | 0.3 | GO:0051189 | molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189) |
| 0.0 | 0.4 | GO:0031468 | nuclear envelope reassembly(GO:0031468) |
| 0.0 | 2.8 | GO:0035914 | skeletal muscle cell differentiation(GO:0035914) |
| 0.0 | 1.3 | GO:0048011 | neurotrophin TRK receptor signaling pathway(GO:0048011) |
| 0.0 | 0.4 | GO:0031118 | rRNA pseudouridine synthesis(GO:0031118) |
| 0.0 | 0.2 | GO:0035752 | lysosomal lumen pH elevation(GO:0035752) |
| 0.0 | 0.7 | GO:0071539 | protein localization to centrosome(GO:0071539) |
| 0.0 | 0.5 | GO:0000132 | establishment of mitotic spindle orientation(GO:0000132) |
| 0.0 | 0.8 | GO:0007099 | centriole replication(GO:0007099) |
| 0.0 | 0.9 | GO:0006783 | heme biosynthetic process(GO:0006783) |
| 0.0 | 4.0 | GO:0051028 | mRNA transport(GO:0051028) |
| 0.0 | 1.6 | GO:0097120 | receptor localization to synapse(GO:0097120) |
| 0.0 | 0.3 | GO:0031111 | negative regulation of microtubule polymerization or depolymerization(GO:0031111) |
| 0.0 | 1.0 | GO:0046827 | positive regulation of protein export from nucleus(GO:0046827) |
| 0.0 | 1.1 | GO:0061028 | establishment of endothelial barrier(GO:0061028) |
| 0.0 | 0.5 | GO:1900025 | Golgi to endosome transport(GO:0006895) negative regulation of substrate adhesion-dependent cell spreading(GO:1900025) |
| 0.0 | 0.7 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 0.0 | 0.1 | GO:0006014 | D-ribose metabolic process(GO:0006014) |
| 0.0 | 1.6 | GO:0070527 | platelet aggregation(GO:0070527) |
| 0.0 | 0.9 | GO:0051225 | spindle assembly(GO:0051225) |
| 0.0 | 0.4 | GO:0002097 | tRNA wobble base modification(GO:0002097) |
| 0.0 | 0.0 | GO:0006041 | glucosamine metabolic process(GO:0006041) |
| 0.0 | 0.3 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
| 0.0 | 0.2 | GO:0061002 | negative regulation of dendritic spine morphogenesis(GO:0061002) |
| 0.0 | 1.4 | GO:0007517 | muscle organ development(GO:0007517) |
| 0.0 | 0.8 | GO:1900047 | negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047) |
| 0.0 | 0.7 | GO:0045104 | intermediate filament cytoskeleton organization(GO:0045104) |
| 0.0 | 0.3 | GO:0070914 | UV-damage excision repair(GO:0070914) |
| 0.0 | 1.8 | GO:0002181 | cytoplasmic translation(GO:0002181) |
| 0.0 | 0.5 | GO:0033045 | regulation of sister chromatid segregation(GO:0033045) |
| 0.0 | 0.1 | GO:1901029 | negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029) |
| 0.0 | 0.6 | GO:0045760 | positive regulation of action potential(GO:0045760) |
| 0.0 | 0.2 | GO:0071494 | cellular response to UV-C(GO:0071494) |
| 0.0 | 0.6 | GO:0060416 | response to growth hormone(GO:0060416) |
| 0.0 | 1.2 | GO:0007368 | determination of left/right symmetry(GO:0007368) |
| 0.0 | 0.4 | GO:1900037 | regulation of cellular response to hypoxia(GO:1900037) |
| 0.0 | 2.6 | GO:0010921 | regulation of phosphatase activity(GO:0010921) |
| 0.0 | 0.4 | GO:0071384 | cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385) |
| 0.0 | 1.0 | GO:0006826 | iron ion transport(GO:0006826) |
| 0.0 | 0.4 | GO:0002088 | lens development in camera-type eye(GO:0002088) |
| 0.0 | 1.5 | GO:0006749 | glutathione metabolic process(GO:0006749) |
| 0.0 | 0.8 | GO:0030520 | intracellular estrogen receptor signaling pathway(GO:0030520) |
| 0.0 | 1.1 | GO:0007019 | microtubule depolymerization(GO:0007019) |
| 0.0 | 0.2 | GO:0070886 | positive regulation of calcineurin-NFAT signaling cascade(GO:0070886) |
| 0.0 | 2.4 | GO:0007093 | mitotic cell cycle checkpoint(GO:0007093) |
| 0.0 | 1.4 | GO:0046847 | filopodium assembly(GO:0046847) |
| 0.0 | 2.1 | GO:0007050 | cell cycle arrest(GO:0007050) |
| 0.0 | 0.9 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.0 | 0.1 | GO:1901642 | purine nucleoside transmembrane transport(GO:0015860) nucleoside transmembrane transport(GO:1901642) |
| 0.0 | 0.7 | GO:0001658 | branching involved in ureteric bud morphogenesis(GO:0001658) |
| 0.0 | 0.1 | GO:0060712 | spongiotrophoblast layer development(GO:0060712) |
| 0.0 | 0.1 | GO:0048665 | neuron fate specification(GO:0048665) |
| 0.0 | 0.2 | GO:0035520 | monoubiquitinated protein deubiquitination(GO:0035520) |
| 0.0 | 0.0 | GO:0070782 | phosphatidylserine exposure on apoptotic cell surface(GO:0070782) |
| 0.0 | 0.7 | GO:0046324 | regulation of glucose import(GO:0046324) |
| 0.0 | 0.4 | GO:0045880 | positive regulation of smoothened signaling pathway(GO:0045880) |
| 0.0 | 0.1 | GO:0030263 | apoptotic chromosome condensation(GO:0030263) |
| 0.0 | 1.1 | GO:0007338 | single fertilization(GO:0007338) |
| 0.0 | 0.5 | GO:0032330 | regulation of chondrocyte differentiation(GO:0032330) |
| 0.0 | 1.0 | GO:0045766 | positive regulation of angiogenesis(GO:0045766) |
| 0.0 | 0.8 | GO:0000086 | G2/M transition of mitotic cell cycle(GO:0000086) |
| 0.0 | 0.4 | GO:0045599 | negative regulation of fat cell differentiation(GO:0045599) |
| 0.0 | 0.2 | GO:0007398 | ectoderm development(GO:0007398) |
| 0.0 | 0.4 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
| 0.0 | 0.3 | GO:0045580 | regulation of T cell differentiation(GO:0045580) |
| 0.0 | 0.3 | GO:0050982 | detection of mechanical stimulus(GO:0050982) |
| 0.0 | 0.2 | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184) |
| 0.0 | 0.1 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 0.0 | 0.1 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.7 | 9.9 | GO:0031262 | Ndc80 complex(GO:0031262) |
| 1.5 | 11.8 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 0.9 | 2.8 | GO:0034457 | Mpp10 complex(GO:0034457) |
| 0.8 | 2.4 | GO:0042584 | chromaffin granule membrane(GO:0042584) |
| 0.8 | 4.8 | GO:0070531 | BRCA1-A complex(GO:0070531) |
| 0.8 | 2.4 | GO:1990423 | RZZ complex(GO:1990423) |
| 0.7 | 2.1 | GO:0031205 | endoplasmic reticulum Sec complex(GO:0031205) |
| 0.7 | 3.5 | GO:0032133 | chromosome passenger complex(GO:0032133) |
| 0.7 | 2.1 | GO:0000799 | nuclear condensin complex(GO:0000799) |
| 0.7 | 3.3 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
| 0.6 | 1.9 | GO:0097058 | CRLF-CLCF1 complex(GO:0097058) |
| 0.5 | 2.7 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
| 0.5 | 4.7 | GO:0061617 | MICOS complex(GO:0061617) |
| 0.5 | 5.9 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.4 | 1.5 | GO:0071942 | XPC complex(GO:0071942) |
| 0.4 | 1.1 | GO:0033186 | CAF-1 complex(GO:0033186) |
| 0.3 | 5.9 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.3 | 1.0 | GO:0070557 | PCNA-p21 complex(GO:0070557) |
| 0.3 | 3.0 | GO:0070545 | PeBoW complex(GO:0070545) |
| 0.3 | 0.8 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
| 0.2 | 1.0 | GO:0017071 | intracellular cyclic nucleotide activated cation channel complex(GO:0017071) |
| 0.2 | 1.0 | GO:0098559 | cytoplasmic side of early endosome membrane(GO:0098559) |
| 0.2 | 3.3 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.2 | 1.0 | GO:0097226 | sperm mitochondrial sheath(GO:0097226) |
| 0.2 | 1.7 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.2 | 1.7 | GO:0036157 | outer dynein arm(GO:0036157) |
| 0.2 | 1.7 | GO:0044291 | cell-cell contact zone(GO:0044291) |
| 0.2 | 1.1 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
| 0.2 | 1.3 | GO:0060293 | P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293) |
| 0.2 | 1.1 | GO:0061689 | paranodal junction(GO:0033010) tricellular tight junction(GO:0061689) |
| 0.2 | 1.1 | GO:0000172 | ribonuclease MRP complex(GO:0000172) |
| 0.2 | 5.8 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.2 | 0.7 | GO:0043259 | laminin-10 complex(GO:0043259) |
| 0.2 | 1.3 | GO:0097413 | Lewy body(GO:0097413) |
| 0.2 | 0.5 | GO:0071001 | U4/U6 snRNP(GO:0071001) |
| 0.2 | 5.6 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.2 | 1.3 | GO:0031315 | extrinsic component of mitochondrial outer membrane(GO:0031315) |
| 0.2 | 0.8 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
| 0.1 | 0.7 | GO:1990246 | uniplex complex(GO:1990246) |
| 0.1 | 0.7 | GO:0032584 | growth cone membrane(GO:0032584) |
| 0.1 | 2.9 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.1 | 0.7 | GO:1990131 | Gtr1-Gtr2 GTPase complex(GO:1990131) |
| 0.1 | 0.4 | GO:0045009 | melanosome membrane(GO:0033162) chitosome(GO:0045009) |
| 0.1 | 0.4 | GO:0035061 | interchromatin granule(GO:0035061) |
| 0.1 | 0.9 | GO:0070652 | HAUS complex(GO:0070652) |
| 0.1 | 0.7 | GO:0098837 | postsynaptic recycling endosome(GO:0098837) |
| 0.1 | 0.8 | GO:0045254 | pyruvate dehydrogenase complex(GO:0045254) |
| 0.1 | 3.9 | GO:0000786 | nucleosome(GO:0000786) |
| 0.1 | 0.9 | GO:0031390 | Ctf18 RFC-like complex(GO:0031390) |
| 0.1 | 1.5 | GO:0042555 | MCM complex(GO:0042555) |
| 0.1 | 0.7 | GO:0097452 | GAIT complex(GO:0097452) |
| 0.1 | 0.4 | GO:0061702 | inflammasome complex(GO:0061702) |
| 0.1 | 1.6 | GO:0000800 | lateral element(GO:0000800) |
| 0.1 | 1.2 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 0.1 | 1.3 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.1 | 0.4 | GO:0032797 | SMN complex(GO:0032797) |
| 0.1 | 1.2 | GO:0045277 | respiratory chain complex IV(GO:0045277) |
| 0.1 | 0.6 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
| 0.1 | 0.8 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
| 0.1 | 4.7 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.1 | 0.4 | GO:0097504 | Gemini of coiled bodies(GO:0097504) |
| 0.1 | 0.7 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.1 | 0.5 | GO:0005964 | phosphorylase kinase complex(GO:0005964) |
| 0.1 | 0.6 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
| 0.1 | 0.6 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
| 0.1 | 0.2 | GO:0097543 | ciliary inversin compartment(GO:0097543) |
| 0.1 | 0.3 | GO:0033063 | Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
| 0.1 | 2.2 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.1 | 1.5 | GO:0000242 | pericentriolar material(GO:0000242) |
| 0.1 | 0.5 | GO:0071203 | WASH complex(GO:0071203) |
| 0.1 | 0.4 | GO:0036195 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
| 0.1 | 0.3 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
| 0.1 | 0.7 | GO:0071598 | neuronal ribonucleoprotein granule(GO:0071598) |
| 0.1 | 3.1 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.1 | 0.7 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
| 0.1 | 0.6 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
| 0.1 | 4.4 | GO:0072686 | mitotic spindle(GO:0072686) |
| 0.1 | 1.0 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.1 | 0.4 | GO:0005664 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
| 0.1 | 0.2 | GO:0097629 | extrinsic component of omegasome membrane(GO:0097629) |
| 0.1 | 2.3 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.1 | 5.2 | GO:0005814 | centriole(GO:0005814) |
| 0.1 | 1.1 | GO:0045120 | pronucleus(GO:0045120) |
| 0.1 | 0.3 | GO:0005859 | muscle myosin complex(GO:0005859) |
| 0.1 | 0.5 | GO:0000243 | commitment complex(GO:0000243) |
| 0.1 | 0.4 | GO:0045261 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261) |
| 0.1 | 1.1 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 0.1 | 0.6 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.1 | 1.1 | GO:0008305 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
| 0.0 | 1.4 | GO:0035869 | ciliary transition zone(GO:0035869) |
| 0.0 | 0.7 | GO:0030008 | TRAPP complex(GO:0030008) |
| 0.0 | 0.7 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
| 0.0 | 4.9 | GO:0000776 | kinetochore(GO:0000776) |
| 0.0 | 2.0 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.0 | 0.7 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.0 | 3.0 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 0.9 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
| 0.0 | 2.6 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.0 | 0.3 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.0 | 0.3 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.0 | 0.4 | GO:0070761 | pre-snoRNP complex(GO:0070761) |
| 0.0 | 0.8 | GO:0002102 | podosome(GO:0002102) |
| 0.0 | 2.4 | GO:0005902 | microvillus(GO:0005902) |
| 0.0 | 1.1 | GO:0099503 | secretory vesicle(GO:0099503) |
| 0.0 | 0.7 | GO:0042611 | MHC protein complex(GO:0042611) |
| 0.0 | 0.7 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.0 | 1.6 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 1.6 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.0 | 1.3 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 0.7 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.0 | 0.7 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
| 0.0 | 0.1 | GO:1990111 | spermatoproteasome complex(GO:1990111) |
| 0.0 | 3.1 | GO:0032993 | protein-DNA complex(GO:0032993) |
| 0.0 | 7.1 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.0 | 0.5 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.0 | 1.5 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.0 | 0.5 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.0 | 0.6 | GO:0030686 | 90S preribosome(GO:0030686) |
| 0.0 | 0.1 | GO:0031467 | Cul7-RING ubiquitin ligase complex(GO:0031467) |
| 0.0 | 1.0 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
| 0.0 | 0.6 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 0.0 | 0.8 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.0 | 7.2 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.0 | 0.9 | GO:0030141 | secretory granule(GO:0030141) |
| 0.0 | 0.9 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.0 | 0.8 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.0 | 0.4 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.0 | 1.3 | GO:0030175 | filopodium(GO:0030175) |
| 0.0 | 0.7 | GO:0005844 | polysome(GO:0005844) |
| 0.0 | 3.0 | GO:0031965 | nuclear membrane(GO:0031965) |
| 0.0 | 1.2 | GO:0036464 | cytoplasmic ribonucleoprotein granule(GO:0036464) |
| 0.0 | 0.1 | GO:0042575 | DNA polymerase complex(GO:0042575) |
| 0.0 | 0.1 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.0 | 1.7 | GO:0005884 | actin filament(GO:0005884) |
| 0.0 | 0.1 | GO:0048188 | MLL3/4 complex(GO:0044666) Set1C/COMPASS complex(GO:0048188) |
| 0.0 | 0.3 | GO:0060170 | ciliary membrane(GO:0060170) |
| 0.0 | 0.4 | GO:0030119 | AP-type membrane coat adaptor complex(GO:0030119) |
| 0.0 | 0.1 | GO:0031083 | BLOC-1 complex(GO:0031083) |
| 0.0 | 0.9 | GO:0030136 | clathrin-coated vesicle(GO:0030136) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.1 | 15.2 | GO:0004731 | purine-nucleoside phosphorylase activity(GO:0004731) |
| 3.0 | 11.8 | GO:0031721 | hemoglobin alpha binding(GO:0031721) |
| 1.1 | 6.8 | GO:0071074 | eukaryotic initiation factor eIF2 binding(GO:0071074) |
| 0.8 | 4.0 | GO:0047134 | protein-disulfide reductase activity(GO:0047134) |
| 0.7 | 3.5 | GO:0035174 | histone serine kinase activity(GO:0035174) |
| 0.5 | 2.7 | GO:0061731 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
| 0.5 | 2.1 | GO:0048408 | epidermal growth factor binding(GO:0048408) |
| 0.5 | 1.5 | GO:0047256 | beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256) |
| 0.5 | 2.4 | GO:0008172 | S-methyltransferase activity(GO:0008172) |
| 0.4 | 2.6 | GO:0031419 | cobalamin binding(GO:0031419) |
| 0.4 | 3.3 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
| 0.4 | 2.8 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 0.4 | 1.2 | GO:0004936 | alpha-adrenergic receptor activity(GO:0004936) |
| 0.4 | 1.5 | GO:0050632 | propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121) |
| 0.4 | 2.3 | GO:0044547 | DNA topoisomerase binding(GO:0044547) |
| 0.4 | 1.1 | GO:0000171 | ribonuclease MRP activity(GO:0000171) |
| 0.3 | 1.4 | GO:0008475 | procollagen-lysine 5-dioxygenase activity(GO:0008475) |
| 0.3 | 2.7 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
| 0.3 | 5.6 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.3 | 1.3 | GO:0004427 | inorganic diphosphatase activity(GO:0004427) |
| 0.3 | 1.0 | GO:0032139 | DNA polymerase processivity factor activity(GO:0030337) dinucleotide insertion or deletion binding(GO:0032139) |
| 0.3 | 1.9 | GO:0001758 | retinal dehydrogenase activity(GO:0001758) |
| 0.3 | 1.2 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
| 0.3 | 0.9 | GO:0035650 | AP-1 adaptor complex binding(GO:0035650) |
| 0.3 | 1.7 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
| 0.3 | 1.7 | GO:0005042 | netrin receptor activity(GO:0005042) |
| 0.3 | 2.0 | GO:0000150 | recombinase activity(GO:0000150) |
| 0.3 | 1.6 | GO:0051429 | corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
| 0.3 | 1.5 | GO:0045545 | syndecan binding(GO:0045545) |
| 0.3 | 0.8 | GO:0003987 | acetate-CoA ligase activity(GO:0003987) |
| 0.2 | 1.7 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
| 0.2 | 0.7 | GO:0016716 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716) |
| 0.2 | 1.4 | GO:0019841 | retinal binding(GO:0016918) retinol binding(GO:0019841) |
| 0.2 | 5.8 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
| 0.2 | 1.6 | GO:1990948 | ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948) |
| 0.2 | 2.2 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.2 | 0.7 | GO:0035605 | peptidyl-cysteine S-nitrosylase activity(GO:0035605) |
| 0.2 | 1.1 | GO:0019960 | C-X3-C chemokine binding(GO:0019960) |
| 0.2 | 3.7 | GO:0016857 | racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857) |
| 0.2 | 0.7 | GO:0017099 | very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099) |
| 0.2 | 1.3 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.2 | 0.9 | GO:0047844 | deoxycytidine deaminase activity(GO:0047844) |
| 0.2 | 1.5 | GO:0008525 | phosphatidylcholine transporter activity(GO:0008525) |
| 0.2 | 1.5 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
| 0.2 | 1.7 | GO:0048403 | brain-derived neurotrophic factor binding(GO:0048403) |
| 0.2 | 1.0 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
| 0.2 | 0.6 | GO:0003996 | acyl-CoA ligase activity(GO:0003996) |
| 0.2 | 1.0 | GO:0001517 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) |
| 0.2 | 2.1 | GO:0016427 | tRNA (cytosine) methyltransferase activity(GO:0016427) |
| 0.2 | 2.3 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.2 | 0.8 | GO:0070976 | TIR domain binding(GO:0070976) |
| 0.2 | 1.7 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 0.2 | 0.7 | GO:0016647 | oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647) |
| 0.2 | 1.7 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
| 0.2 | 2.0 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
| 0.2 | 0.4 | GO:0019966 | interleukin-1 binding(GO:0019966) |
| 0.2 | 0.7 | GO:0000268 | peroxisome targeting sequence binding(GO:0000268) |
| 0.2 | 0.5 | GO:0018738 | S-formylglutathione hydrolase activity(GO:0018738) |
| 0.2 | 0.7 | GO:0004459 | L-lactate dehydrogenase activity(GO:0004459) |
| 0.2 | 1.1 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 0.2 | 2.3 | GO:0003995 | acyl-CoA dehydrogenase activity(GO:0003995) |
| 0.2 | 0.6 | GO:0003998 | acylphosphatase activity(GO:0003998) |
| 0.2 | 1.2 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
| 0.2 | 0.8 | GO:0016668 | oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668) |
| 0.1 | 3.3 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 0.1 | 0.6 | GO:0030984 | kininogen binding(GO:0030984) |
| 0.1 | 1.9 | GO:0005522 | profilin binding(GO:0005522) |
| 0.1 | 0.6 | GO:0097108 | hedgehog family protein binding(GO:0097108) |
| 0.1 | 0.4 | GO:0036132 | 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522) |
| 0.1 | 0.4 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
| 0.1 | 1.8 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 0.1 | 0.7 | GO:0016854 | racemase and epimerase activity(GO:0016854) |
| 0.1 | 2.6 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.1 | 1.9 | GO:0048038 | quinone binding(GO:0048038) |
| 0.1 | 0.8 | GO:0032795 | heterotrimeric G-protein binding(GO:0032795) |
| 0.1 | 1.9 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
| 0.1 | 1.8 | GO:0016805 | dipeptidase activity(GO:0016805) |
| 0.1 | 0.5 | GO:0003976 | UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976) |
| 0.1 | 1.4 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.1 | 0.9 | GO:0048101 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
| 0.1 | 2.3 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.1 | 2.1 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.1 | 5.9 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.1 | 1.1 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
| 0.1 | 4.2 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.1 | 0.3 | GO:1990450 | linear polyubiquitin binding(GO:1990450) |
| 0.1 | 0.7 | GO:0071558 | histone demethylase activity (H3-K27 specific)(GO:0071558) |
| 0.1 | 0.5 | GO:0004322 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.1 | 0.5 | GO:0030621 | U4 snRNA binding(GO:0030621) |
| 0.1 | 2.2 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.1 | 0.3 | GO:0004758 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
| 0.1 | 2.7 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.1 | 0.4 | GO:0031735 | CCR10 chemokine receptor binding(GO:0031735) |
| 0.1 | 0.6 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
| 0.1 | 1.3 | GO:0046527 | glucosyltransferase activity(GO:0046527) |
| 0.1 | 1.1 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.1 | 1.7 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629) |
| 0.1 | 0.3 | GO:0036468 | aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468) |
| 0.1 | 0.7 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
| 0.1 | 0.7 | GO:0003964 | telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964) |
| 0.1 | 0.9 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 0.1 | 1.4 | GO:0003708 | retinoic acid receptor activity(GO:0003708) |
| 0.1 | 1.4 | GO:0001222 | transcription corepressor binding(GO:0001222) |
| 0.1 | 1.7 | GO:0045505 | dynein intermediate chain binding(GO:0045505) |
| 0.1 | 1.7 | GO:0005521 | lamin binding(GO:0005521) |
| 0.1 | 0.3 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
| 0.1 | 3.1 | GO:0004407 | histone deacetylase activity(GO:0004407) |
| 0.1 | 0.5 | GO:0004689 | phosphorylase kinase activity(GO:0004689) |
| 0.1 | 0.2 | GO:0004090 | carbonyl reductase (NADPH) activity(GO:0004090) |
| 0.1 | 0.9 | GO:0000014 | single-stranded DNA endodeoxyribonuclease activity(GO:0000014) |
| 0.1 | 0.5 | GO:0061665 | SUMO ligase activity(GO:0061665) |
| 0.1 | 0.3 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.1 | 0.7 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 0.1 | 0.4 | GO:0001094 | TFIID-class transcription factor binding(GO:0001094) |
| 0.1 | 3.0 | GO:0003684 | damaged DNA binding(GO:0003684) |
| 0.1 | 0.3 | GO:0004392 | heme oxygenase (decyclizing) activity(GO:0004392) |
| 0.1 | 1.5 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.1 | 1.4 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.1 | 2.9 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 0.1 | 0.2 | GO:0050347 | trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347) |
| 0.1 | 0.5 | GO:1990446 | U1 snRNP binding(GO:1990446) |
| 0.1 | 0.4 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
| 0.1 | 0.3 | GO:0032767 | copper-dependent protein binding(GO:0032767) |
| 0.1 | 0.6 | GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity(GO:0051575) |
| 0.1 | 0.4 | GO:0050733 | RS domain binding(GO:0050733) |
| 0.1 | 1.3 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
| 0.1 | 1.0 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.1 | 0.7 | GO:0004576 | oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.1 | 0.7 | GO:0019215 | intermediate filament binding(GO:0019215) |
| 0.1 | 0.5 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
| 0.1 | 0.7 | GO:0002161 | aminoacyl-tRNA editing activity(GO:0002161) |
| 0.1 | 0.4 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.1 | 0.5 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 0.0 | 0.4 | GO:0070403 | NAD+ binding(GO:0070403) |
| 0.0 | 0.7 | GO:0070402 | NADPH binding(GO:0070402) |
| 0.0 | 0.1 | GO:0019863 | IgE binding(GO:0019863) |
| 0.0 | 0.2 | GO:0001010 | transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) |
| 0.0 | 1.5 | GO:0071837 | HMG box domain binding(GO:0071837) |
| 0.0 | 0.5 | GO:0070567 | cytidylyltransferase activity(GO:0070567) |
| 0.0 | 0.3 | GO:0002135 | CTP binding(GO:0002135) |
| 0.0 | 1.4 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.0 | 0.3 | GO:0015125 | bile acid transmembrane transporter activity(GO:0015125) |
| 0.0 | 0.7 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.0 | 1.1 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
| 0.0 | 0.4 | GO:0019103 | pyrimidine nucleotide binding(GO:0019103) |
| 0.0 | 0.3 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
| 0.0 | 1.5 | GO:0016776 | phosphotransferase activity, phosphate group as acceptor(GO:0016776) |
| 0.0 | 1.0 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 0.0 | 1.3 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
| 0.0 | 1.7 | GO:0005160 | transforming growth factor beta receptor binding(GO:0005160) |
| 0.0 | 0.6 | GO:0051920 | peroxiredoxin activity(GO:0051920) |
| 0.0 | 1.3 | GO:0016835 | carbon-oxygen lyase activity(GO:0016835) |
| 0.0 | 0.4 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.0 | 0.2 | GO:0051525 | NFAT protein binding(GO:0051525) |
| 0.0 | 0.4 | GO:0004000 | adenosine deaminase activity(GO:0004000) |
| 0.0 | 1.0 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 0.0 | 2.2 | GO:0008186 | RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186) |
| 0.0 | 0.2 | GO:0061676 | importin-alpha family protein binding(GO:0061676) |
| 0.0 | 0.4 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
| 0.0 | 1.2 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.0 | 1.4 | GO:0016651 | oxidoreductase activity, acting on NAD(P)H(GO:0016651) |
| 0.0 | 0.4 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
| 0.0 | 0.8 | GO:0031369 | translation initiation factor binding(GO:0031369) |
| 0.0 | 0.6 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.0 | 0.6 | GO:0030515 | snoRNA binding(GO:0030515) |
| 0.0 | 0.4 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
| 0.0 | 0.1 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
| 0.0 | 0.3 | GO:0030169 | low-density lipoprotein particle binding(GO:0030169) |
| 0.0 | 1.4 | GO:0019003 | GDP binding(GO:0019003) |
| 0.0 | 1.3 | GO:0019843 | rRNA binding(GO:0019843) |
| 0.0 | 0.3 | GO:0016783 | sulfurtransferase activity(GO:0016783) |
| 0.0 | 0.3 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
| 0.0 | 0.3 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.0 | 0.2 | GO:0015187 | glycine transmembrane transporter activity(GO:0015187) |
| 0.0 | 0.1 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 0.0 | 0.8 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.0 | 0.1 | GO:0008192 | RNA guanylyltransferase activity(GO:0008192) |
| 0.0 | 0.1 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.0 | 1.6 | GO:0019905 | syntaxin binding(GO:0019905) |
| 0.0 | 0.4 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.0 | 0.3 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
| 0.0 | 1.1 | GO:0005125 | cytokine activity(GO:0005125) |
| 0.0 | 0.4 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.0 | 0.1 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
| 0.0 | 2.3 | GO:0003714 | transcription corepressor activity(GO:0003714) |
| 0.0 | 0.4 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.0 | 0.5 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
| 0.0 | 2.6 | GO:0008017 | microtubule binding(GO:0008017) |
| 0.0 | 1.1 | GO:0005178 | integrin binding(GO:0005178) |
| 0.0 | 0.3 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.0 | 1.0 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 0.5 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 0.2 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.0 | 0.0 | GO:0035368 | selenocysteine insertion sequence binding(GO:0035368) |
| 0.0 | 0.6 | GO:0003682 | chromatin binding(GO:0003682) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 0.3 | ST_JAK_STAT_PATHWAY | Jak-STAT Pathway |
| 0.3 | 13.0 | PID_AURORA_B_PATHWAY | Aurora B signaling |
| 0.2 | 8.5 | PID_BARD1_PATHWAY | BARD1 signaling events |
| 0.2 | 9.8 | PID_RET_PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.1 | 1.4 | SA_MMP_CYTOKINE_CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.1 | 3.9 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
| 0.1 | 2.8 | PID_SMAD2_3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.1 | 0.8 | PID_TCR_JNK_PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.1 | 3.1 | PID_INSULIN_GLUCOSE_PATHWAY | Insulin-mediated glucose transport |
| 0.1 | 0.7 | PID_INTEGRIN4_PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.1 | 7.9 | PID_MYC_ACTIV_PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.1 | 0.8 | ST_INTERFERON_GAMMA_PATHWAY | Interferon gamma pathway. |
| 0.1 | 1.3 | PID_LYMPH_ANGIOGENESIS_PATHWAY | VEGFR3 signaling in lymphatic endothelium |
| 0.1 | 4.0 | PID_HEDGEHOG_GLI_PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.1 | 0.2 | PID_PI3KCI_AKT_PATHWAY | Class I PI3K signaling events mediated by Akt |
| 0.1 | 1.9 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
| 0.1 | 4.2 | PID_RHOA_REG_PATHWAY | Regulation of RhoA activity |
| 0.1 | 1.7 | PID_NETRIN_PATHWAY | Netrin-mediated signaling events |
| 0.1 | 3.0 | PID_CASPASE_PATHWAY | Caspase cascade in apoptosis |
| 0.1 | 0.8 | PID_ERB_GENOMIC_PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.0 | 0.8 | PID_IL27_PATHWAY | IL27-mediated signaling events |
| 0.0 | 2.4 | PID_P75_NTR_PATHWAY | p75(NTR)-mediated signaling |
| 0.0 | 4.1 | PID_NOTCH_PATHWAY | Notch signaling pathway |
| 0.0 | 1.4 | PID_RETINOIC_ACID_PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.0 | 1.8 | PID_ERBB4_PATHWAY | ErbB4 signaling events |
| 0.0 | 0.4 | PID_RHODOPSIN_PATHWAY | Visual signal transduction: Rods |
| 0.0 | 1.6 | ST_JNK_MAPK_PATHWAY | JNK MAPK Pathway |
| 0.0 | 0.9 | ST_WNT_CA2_CYCLIC_GMP_PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.0 | 0.2 | PID_FRA_PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.0 | 0.2 | PID_ERBB_NETWORK_PATHWAY | ErbB receptor signaling network |
| 0.0 | 0.8 | PID_HDAC_CLASSIII_PATHWAY | Signaling events mediated by HDAC Class III |
| 0.0 | 0.8 | PID_DNA_PK_PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.0 | 0.7 | PID_ATM_PATHWAY | ATM pathway |
| 0.0 | 0.9 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
| 0.0 | 1.5 | PID_ERA_GENOMIC_PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 1.0 | PID_FCER1_PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 0.0 | 0.4 | PID_PDGFRA_PATHWAY | PDGFR-alpha signaling pathway |
| 0.0 | 1.9 | PID_ERBB1_DOWNSTREAM_PATHWAY | ErbB1 downstream signaling |
| 0.0 | 0.6 | PID_EPHB_FWD_PATHWAY | EPHB forward signaling |
| 0.0 | 0.4 | PID_KIT_PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.0 | 2.8 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 0.4 | PID_ALPHA_SYNUCLEIN_PATHWAY | Alpha-synuclein signaling |
| 0.0 | 0.5 | NABA_COLLAGENS | Genes encoding collagen proteins |
| 0.0 | 0.6 | PID_ILK_PATHWAY | Integrin-linked kinase signaling |
| 0.0 | 2.5 | NABA_SECRETED_FACTORS | Genes encoding secreted soluble factors |
| 0.0 | 0.3 | PID_FANCONI_PATHWAY | Fanconi anemia pathway |
| 0.0 | 0.4 | PID_DELTA_NP63_PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 14.2 | REACTOME_PURINE_CATABOLISM | Genes involved in Purine catabolism |
| 0.4 | 6.8 | REACTOME_ACTIVATION_OF_RAC | Genes involved in Activation of Rac |
| 0.2 | 25.6 | REACTOME_MITOTIC_PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.2 | 3.7 | REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
| 0.2 | 3.3 | REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.2 | 0.8 | REACTOME_ETHANOL_OXIDATION | Genes involved in Ethanol oxidation |
| 0.2 | 3.9 | REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.2 | 3.3 | REACTOME_G1_S_SPECIFIC_TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 0.2 | 1.2 | REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT | Genes involved in Initial triggering of complement |
| 0.2 | 1.7 | REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING | Genes involved in Role of second messengers in netrin-1 signaling |
| 0.1 | 1.5 | REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol |
| 0.1 | 2.8 | REACTOME_REGULATION_OF_KIT_SIGNALING | Genes involved in Regulation of KIT signaling |
| 0.1 | 2.7 | REACTOME_CHOLESTEROL_BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.1 | 1.2 | REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.1 | 1.6 | REACTOME_UNWINDING_OF_DNA | Genes involved in Unwinding of DNA |
| 0.1 | 1.2 | REACTOME_IL_6_SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.1 | 5.7 | REACTOME_MEIOTIC_RECOMBINATION | Genes involved in Meiotic Recombination |
| 0.1 | 2.1 | REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.1 | 0.8 | REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING | Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling |
| 0.1 | 1.1 | REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.1 | 0.8 | REACTOME_GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.1 | 3.2 | REACTOME_PHASE_II_CONJUGATION | Genes involved in Phase II conjugation |
| 0.1 | 1.7 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.1 | 1.0 | REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
| 0.1 | 1.4 | REACTOME_G_ALPHA1213_SIGNALLING_EVENTS | Genes involved in G alpha (12/13) signalling events |
| 0.1 | 0.4 | REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION | Genes involved in E2F-enabled inhibition of pre-replication complex formation |
| 0.1 | 2.7 | REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
| 0.1 | 2.9 | REACTOME_GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.1 | 1.5 | REACTOME_HS_GAG_DEGRADATION | Genes involved in HS-GAG degradation |
| 0.1 | 4.4 | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT | Genes involved in Respiratory electron transport |
| 0.1 | 0.9 | REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
| 0.1 | 2.1 | REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT | Genes involved in Regulation of beta-cell development |
| 0.1 | 2.0 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.1 | 0.3 | REACTOME_REGULATION_OF_IFNG_SIGNALING | Genes involved in Regulation of IFNG signaling |
| 0.1 | 1.2 | REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
| 0.1 | 1.7 | REACTOME_IL1_SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.1 | 2.3 | REACTOME_MRNA_3_END_PROCESSING | Genes involved in mRNA 3'-end processing |
| 0.0 | 0.5 | REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES | Genes involved in Generation of second messenger molecules |
| 0.0 | 1.6 | REACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR | Genes involved in Prostacyclin signalling through prostacyclin receptor |
| 0.0 | 0.8 | REACTOME_SIGNAL_ATTENUATION | Genes involved in Signal attenuation |
| 0.0 | 0.6 | REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 0.0 | 7.5 | REACTOME_SIGNALING_BY_RHO_GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.0 | 0.5 | REACTOME_ENOS_ACTIVATION_AND_REGULATION | Genes involved in eNOS activation and regulation |
| 0.0 | 5.4 | REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE | Genes involved in SRP-dependent cotranslational protein targeting to membrane |
| 0.0 | 0.7 | REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER | Genes involved in Formation of incision complex in GG-NER |
| 0.0 | 0.5 | REACTOME_PHOSPHORYLATION_OF_THE_APC_C | Genes involved in Phosphorylation of the APC/C |
| 0.0 | 0.6 | REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.0 | 0.5 | REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.0 | 0.3 | REACTOME_AMINE_DERIVED_HORMONES | Genes involved in Amine-derived hormones |
| 0.0 | 1.9 | REACTOME_COLLAGEN_FORMATION | Genes involved in Collagen formation |
| 0.0 | 0.7 | REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.0 | 0.2 | REACTOME_RAP1_SIGNALLING | Genes involved in Rap1 signalling |
| 0.0 | 0.4 | REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP | Genes involved in Destabilization of mRNA by KSRP |
| 0.0 | 0.9 | REACTOME_CA_DEPENDENT_EVENTS | Genes involved in Ca-dependent events |
| 0.0 | 0.4 | REACTOME_INFLAMMASOMES | Genes involved in Inflammasomes |
| 0.0 | 0.2 | REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.0 | 0.3 | REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
| 0.0 | 0.5 | REACTOME_METAL_ION_SLC_TRANSPORTERS | Genes involved in Metal ion SLC transporters |
| 0.0 | 0.3 | REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 0.0 | 0.3 | REACTOME_G0_AND_EARLY_G1 | Genes involved in G0 and Early G1 |
| 0.0 | 0.4 | REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.0 | 0.7 | REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.0 | 1.0 | REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.0 | 0.9 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.0 | 0.1 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.0 | 0.2 | REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
| 0.0 | 0.1 | REACTOME_CALNEXIN_CALRETICULIN_CYCLE | Genes involved in Calnexin/calreticulin cycle |
| 0.0 | 1.1 | REACTOME_MRNA_SPLICING | Genes involved in mRNA Splicing |
| 0.0 | 0.3 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.0 | 0.1 | REACTOME_INTRINSIC_PATHWAY | Genes involved in Intrinsic Pathway |
| 0.0 | 0.7 | REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS | Genes involved in Integrin cell surface interactions |
