Motif ID: Cpeb1

Z-value: 1.738


Transcription factors associated with Cpeb1:

Gene SymbolEntrez IDGene Name
Cpeb1 ENSMUSG00000025586.10 Cpeb1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cpeb1mm10_v2_chr7_-_81454751_81454764-0.152.6e-01Click!


Activity profile for motif Cpeb1.

activity profile for motif Cpeb1


Sorted Z-values histogram for motif Cpeb1

Sorted Z-values for motif Cpeb1



Network of associatons between targets according to the STRING database.



First level regulatory network of Cpeb1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_26229707 28.306 ENSMUST00000060716.5
ENSMUST00000164660.1
 Samd3

sterile alpha motif domain containing 3

chr3_-_63851251 22.856 ENSMUST00000162269.2
ENSMUST00000159676.2
ENSMUST00000175947.1
 Plch1


phospholipase C, eta 1


chr2_-_51149100 21.528 ENSMUST00000154545.1
ENSMUST00000017288.2
 Rnd3

Rho family GTPase 3

chr1_+_6730051 21.286 ENSMUST00000043578.6
ENSMUST00000131467.1
ENSMUST00000150761.1
ENSMUST00000151281.1
 St18



suppression of tumorigenicity 18



chr1_-_138842429 19.945 ENSMUST00000112026.2
ENSMUST00000019374.7
 Lhx9

LIM homeobox protein 9

chr3_+_5218546 19.180 ENSMUST00000026284.6
 Zfhx4
zinc finger homeodomain 4
chr2_-_18048784 18.415 ENSMUST00000142856.1
 Skida1
SKI/DACH domain containing 1
chr14_-_48667508 18.207 ENSMUST00000144465.1
ENSMUST00000133479.1
ENSMUST00000119070.1
ENSMUST00000152018.1
 Otx2



orthodenticle homolog 2 (Drosophila)



chr1_+_6734827 16.891 ENSMUST00000139838.1
 St18
suppression of tumorigenicity 18
chr7_-_103853199 16.802 ENSMUST00000033229.3
 Hbb-y
hemoglobin Y, beta-like embryonic chain
chr3_+_87948666 16.622 ENSMUST00000005019.5
 Crabp2
cellular retinoic acid binding protein II
chr3_+_5218516 16.086 ENSMUST00000175866.1
 Zfhx4
zinc finger homeodomain 4
chr11_-_99024179 15.753 ENSMUST00000068031.7
 Top2a
topoisomerase (DNA) II alpha
chr2_-_137116624 14.970 ENSMUST00000028735.7
 Jag1
jagged 1
chr1_+_6730135 14.755 ENSMUST00000155921.1
 St18
suppression of tumorigenicity 18
chr2_-_18048347 13.689 ENSMUST00000066885.5
 Skida1
SKI/DACH domain containing 1
chr12_-_54986328 12.507 ENSMUST00000038926.6
 Baz1a
bromodomain adjacent to zinc finger domain 1A
chr12_-_54986363 12.322 ENSMUST00000173433.1
ENSMUST00000173803.1
 Baz1a
Gm20403
bromodomain adjacent to zinc finger domain 1A
predicted gene 20403
chr19_+_55741810 12.230 ENSMUST00000111657.3
ENSMUST00000061496.9
ENSMUST00000041717.7
ENSMUST00000111662.4
 Tcf7l2



transcription factor 7 like 2, T cell specific, HMG box



chr17_+_43953191 11.770 ENSMUST00000044792.4
 Rcan2
regulator of calcineurin 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 176 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.4 52.9 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
3.2 25.8 GO:0048625 myoblast fate commitment(GO:0048625)
6.0 23.9 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
1.5 23.0 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.5 21.1 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
4.0 19.9 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 19.4 GO:0006261 DNA-dependent DNA replication(GO:0006261)
3.4 16.8 GO:0015671 oxygen transport(GO:0015671)
3.9 15.8 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
3.0 15.0 GO:0061073 ciliary body morphogenesis(GO:0061073)
2.8 14.2 GO:0021905 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
0.8 13.2 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
1.2 13.1 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.8 12.9 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.6 12.0 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.1 11.5 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015) inositol lipid-mediated signaling(GO:0048017)
0.1 11.5 GO:0060348 bone development(GO:0060348)
0.9 11.3 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
1.1 10.9 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
1.1 10.7 GO:0048664 neuron fate determination(GO:0048664)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 87 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 55.3 GO:0032993 protein-DNA complex(GO:0032993)
0.1 41.8 GO:0005912 adherens junction(GO:0005912)
3.1 28.0 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
6.2 24.8 GO:0008623 CHRAC(GO:0008623)
0.1 22.9 GO:0016607 nuclear speck(GO:0016607)
0.2 17.1 GO:0005814 centriole(GO:0005814)
0.5 12.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 12.8 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.3 10.0 GO:0051233 spindle midzone(GO:0051233)
0.1 9.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
1.3 8.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.1 7.6 GO:0001669 acrosomal vesicle(GO:0001669)
1.8 7.3 GO:0045098 type III intermediate filament(GO:0045098)
1.2 7.2 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 6.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.2 6.6 GO:1990391 DNA repair complex(GO:1990391)
0.8 6.5 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.5 6.5 GO:0042788 polysomal ribosome(GO:0042788)
0.6 6.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.2 6.4 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 133 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 63.9 GO:0001047 core promoter binding(GO:0001047)
0.1 45.9 GO:0008270 zinc ion binding(GO:0008270)
0.3 23.8 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
1.1 23.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
1.2 22.9 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 20.0 GO:0003924 GTPase activity(GO:0003924)
0.1 19.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 17.4 GO:0019904 protein domain specific binding(GO:0019904)
3.4 16.8 GO:0005344 oxygen transporter activity(GO:0005344)
2.8 16.6 GO:0019841 retinol binding(GO:0019841)
3.9 15.8 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
1.0 15.2 GO:0003680 AT DNA binding(GO:0003680)
0.4 15.2 GO:0005112 Notch binding(GO:0005112)
0.1 13.8 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
1.9 13.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
2.0 11.8 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 11.4 GO:0002039 p53 binding(GO:0002039)
0.4 11.3 GO:0032452 histone demethylase activity(GO:0032452)
0.0 11.2 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 10.5 GO:0004222 metalloendopeptidase activity(GO:0004222)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 30.5 PID_AP1_PATHWAY AP-1 transcription factor network
0.4 18.7 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.3 15.0 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.3 13.3 PID_AURORA_B_PATHWAY Aurora B signaling
0.4 13.1 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.3 12.4 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.2 11.8 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.5 11.6 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 10.7 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 10.2 PID_CDC42_PATHWAY CDC42 signaling events
0.1 8.4 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.4 7.1 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.2 7.1 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.2 6.3 NABA_COLLAGENS Genes encoding collagen proteins
0.2 5.5 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.3 4.9 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.2 4.9 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.4 4.6 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.1 4.6 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.2 4.0 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 59 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 15.0 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
1.0 14.2 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 13.8 REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS Genes involved in G alpha (q) signalling events
0.4 13.3 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.2 12.0 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.4 10.1 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.1 8.3 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.3 8.1 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 7.9 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 7.7 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.4 7.1 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 7.1 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.2 7.0 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
2.2 6.5 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
0.4 5.8 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.2 5.6 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.1 5.4 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.2 5.3 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.1 5.2 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.7 5.0 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins