Motif ID: Ctcfl_Ctcf
Z-value: 0.963
Transcription factors associated with Ctcfl_Ctcf:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Ctcf | ENSMUSG00000005698.9 | Ctcf |
| Ctcfl | ENSMUSG00000070495.5 | Ctcfl |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Ctcfl | mm10_v2_chr2_-_173119402_173119525 | -0.14 | 3.2e-01 | Click! |
| Ctcf | mm10_v2_chr8_+_105636509_105636589 | 0.05 | 7.3e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.7 | 8.2 | GO:0016256 | N-glycan processing to lysosome(GO:0016256) |
| 2.7 | 10.9 | GO:0044268 | multicellular organismal protein metabolic process(GO:0044268) |
| 2.5 | 7.6 | GO:0043181 | vacuolar sequestering(GO:0043181) |
| 2.3 | 9.2 | GO:1900740 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) |
| 2.3 | 20.3 | GO:1900034 | regulation of cellular response to heat(GO:1900034) |
| 2.3 | 11.3 | GO:0002121 | inter-male aggressive behavior(GO:0002121) |
| 2.2 | 6.7 | GO:1903348 | positive regulation of bicellular tight junction assembly(GO:1903348) |
| 2.2 | 15.5 | GO:0016185 | synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) |
| 2.1 | 8.3 | GO:0099566 | regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566) |
| 1.9 | 7.8 | GO:1901492 | positive regulation of lymphangiogenesis(GO:1901492) |
| 1.9 | 5.7 | GO:0051542 | elastin biosynthetic process(GO:0051542) |
| 1.7 | 5.2 | GO:1902630 | regulation of membrane hyperpolarization(GO:1902630) |
| 1.7 | 5.1 | GO:0046340 | diacylglycerol catabolic process(GO:0046340) |
| 1.5 | 4.5 | GO:2000344 | positive regulation of acrosome reaction(GO:2000344) |
| 1.5 | 2.9 | GO:0002636 | positive regulation of germinal center formation(GO:0002636) |
| 1.4 | 4.2 | GO:0032241 | positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256) |
| 1.3 | 6.7 | GO:2001015 | negative regulation of skeletal muscle cell differentiation(GO:2001015) |
| 1.3 | 3.8 | GO:0051892 | negative regulation of cardioblast differentiation(GO:0051892) |
| 1.2 | 5.9 | GO:0043314 | negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313) |
| 1.1 | 5.6 | GO:0046684 | response to pyrethroid(GO:0046684) |
| 0.9 | 2.8 | GO:0050925 | negative regulation of negative chemotaxis(GO:0050925) |
| 0.9 | 2.7 | GO:0043988 | histone H3-S28 phosphorylation(GO:0043988) |
| 0.9 | 4.4 | GO:0045163 | clustering of voltage-gated potassium channels(GO:0045163) |
| 0.8 | 2.5 | GO:0033634 | positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) |
| 0.8 | 6.7 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
| 0.8 | 6.3 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
| 0.6 | 1.9 | GO:0097155 | fasciculation of sensory neuron axon(GO:0097155) |
| 0.6 | 1.9 | GO:0045113 | regulation of integrin biosynthetic process(GO:0045113) |
| 0.6 | 2.9 | GO:1990034 | calcium ion export from cell(GO:1990034) |
| 0.6 | 1.7 | GO:0018008 | N-terminal peptidyl-glycine N-myristoylation(GO:0018008) |
| 0.6 | 3.9 | GO:0060666 | dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666) |
| 0.6 | 1.7 | GO:0003289 | endocardial cushion fusion(GO:0003274) atrial septum primum morphogenesis(GO:0003289) |
| 0.5 | 2.7 | GO:0010637 | diet induced thermogenesis(GO:0002024) negative regulation of mitochondrial fusion(GO:0010637) |
| 0.5 | 1.6 | GO:0035799 | ureter maturation(GO:0035799) |
| 0.5 | 3.2 | GO:0071630 | nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630) |
| 0.5 | 3.2 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
| 0.5 | 3.0 | GO:0098964 | dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964) |
| 0.5 | 4.2 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
| 0.5 | 3.7 | GO:1903207 | neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208) |
| 0.5 | 2.3 | GO:0001705 | ectoderm formation(GO:0001705) ectodermal cell differentiation(GO:0010668) |
| 0.5 | 1.4 | GO:1904211 | membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211) |
| 0.4 | 1.3 | GO:0009838 | abscission(GO:0009838) positive regulation of viral budding via host ESCRT complex(GO:1903774) |
| 0.4 | 1.3 | GO:0000448 | cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448) |
| 0.4 | 1.7 | GO:0046898 | response to cycloheximide(GO:0046898) |
| 0.4 | 1.2 | GO:0006097 | glyoxylate cycle(GO:0006097) |
| 0.4 | 2.9 | GO:0043983 | histone H4-K12 acetylation(GO:0043983) |
| 0.4 | 0.8 | GO:1900126 | negative regulation of hyaluronan biosynthetic process(GO:1900126) |
| 0.4 | 1.2 | GO:0035973 | aggrephagy(GO:0035973) |
| 0.4 | 4.2 | GO:0030432 | peristalsis(GO:0030432) |
| 0.4 | 16.3 | GO:0007212 | dopamine receptor signaling pathway(GO:0007212) |
| 0.4 | 1.5 | GO:0072362 | regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362) |
| 0.4 | 1.1 | GO:0016095 | polyprenol catabolic process(GO:0016095) |
| 0.4 | 1.5 | GO:0006102 | isocitrate metabolic process(GO:0006102) |
| 0.4 | 7.1 | GO:0042297 | vocal learning(GO:0042297) imitative learning(GO:0098596) |
| 0.4 | 1.1 | GO:0030827 | negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283) |
| 0.4 | 3.2 | GO:0019227 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
| 0.3 | 1.4 | GO:0035624 | receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) |
| 0.3 | 2.1 | GO:0097646 | dimeric G-protein coupled receptor signaling pathway(GO:0038042) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647) |
| 0.3 | 6.9 | GO:0051764 | actin crosslink formation(GO:0051764) |
| 0.3 | 4.5 | GO:0034472 | snRNA 3'-end processing(GO:0034472) |
| 0.3 | 1.3 | GO:0006751 | glutathione catabolic process(GO:0006751) |
| 0.3 | 1.3 | GO:0019919 | peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919) |
| 0.3 | 0.9 | GO:0071033 | generation of catalytic spliceosome for second transesterification step(GO:0000350) nuclear retention of pre-mRNA at the site of transcription(GO:0071033) |
| 0.3 | 2.4 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
| 0.3 | 0.9 | GO:0046013 | regulation of T cell homeostatic proliferation(GO:0046013) |
| 0.3 | 3.0 | GO:0051152 | positive regulation of smooth muscle cell differentiation(GO:0051152) |
| 0.3 | 0.8 | GO:0007181 | transforming growth factor beta receptor complex assembly(GO:0007181) |
| 0.3 | 1.1 | GO:0021882 | regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) |
| 0.3 | 0.8 | GO:0009826 | unidimensional cell growth(GO:0009826) susceptibility to natural killer cell mediated cytotoxicity(GO:0042271) |
| 0.3 | 1.5 | GO:0043654 | recognition of apoptotic cell(GO:0043654) |
| 0.2 | 1.1 | GO:1903336 | negative regulation of vacuolar transport(GO:1903336) |
| 0.2 | 0.7 | GO:0072425 | signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434) |
| 0.2 | 0.4 | GO:0034140 | negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) |
| 0.2 | 0.6 | GO:0018343 | protein farnesylation(GO:0018343) |
| 0.2 | 1.4 | GO:0050919 | negative chemotaxis(GO:0050919) |
| 0.2 | 1.0 | GO:0098703 | parathyroid hormone secretion(GO:0035898) calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035) |
| 0.2 | 6.1 | GO:0061098 | positive regulation of protein tyrosine kinase activity(GO:0061098) |
| 0.2 | 1.1 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
| 0.2 | 2.8 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.2 | 1.8 | GO:0051683 | establishment of Golgi localization(GO:0051683) |
| 0.2 | 0.9 | GO:1901727 | positive regulation of histone deacetylase activity(GO:1901727) |
| 0.2 | 2.9 | GO:0014051 | gamma-aminobutyric acid secretion(GO:0014051) |
| 0.2 | 28.5 | GO:0007416 | synapse assembly(GO:0007416) |
| 0.2 | 3.1 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
| 0.2 | 2.3 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
| 0.2 | 2.1 | GO:0038180 | nerve growth factor signaling pathway(GO:0038180) |
| 0.2 | 3.8 | GO:0001539 | cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285) |
| 0.2 | 1.0 | GO:0060665 | regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665) |
| 0.2 | 3.5 | GO:0030803 | negative regulation of cyclic nucleotide biosynthetic process(GO:0030803) |
| 0.2 | 1.6 | GO:0006450 | regulation of translational fidelity(GO:0006450) |
| 0.2 | 1.1 | GO:0032380 | regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383) |
| 0.2 | 1.3 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
| 0.2 | 3.0 | GO:0034389 | lipid particle organization(GO:0034389) |
| 0.2 | 1.6 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
| 0.2 | 1.1 | GO:0015808 | L-alanine transport(GO:0015808) |
| 0.2 | 2.8 | GO:0047497 | establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) |
| 0.2 | 0.9 | GO:0000707 | meiotic DNA recombinase assembly(GO:0000707) |
| 0.2 | 1.7 | GO:0010807 | regulation of synaptic vesicle priming(GO:0010807) |
| 0.1 | 1.7 | GO:0006857 | oligopeptide transport(GO:0006857) prostaglandin transport(GO:0015732) |
| 0.1 | 2.5 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
| 0.1 | 3.5 | GO:0032933 | response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501) |
| 0.1 | 2.3 | GO:0035721 | intraciliary retrograde transport(GO:0035721) |
| 0.1 | 2.5 | GO:0099612 | protein localization to axon(GO:0099612) |
| 0.1 | 4.6 | GO:0060765 | regulation of androgen receptor signaling pathway(GO:0060765) |
| 0.1 | 0.4 | GO:1904017 | response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017) |
| 0.1 | 2.7 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 0.1 | 1.0 | GO:0007016 | cytoskeletal anchoring at plasma membrane(GO:0007016) |
| 0.1 | 2.1 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
| 0.1 | 2.4 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.1 | 0.5 | GO:0051562 | negative regulation of mitochondrial calcium ion concentration(GO:0051562) |
| 0.1 | 0.4 | GO:1904569 | regulation of selenocysteine incorporation(GO:1904569) |
| 0.1 | 1.3 | GO:0032026 | response to magnesium ion(GO:0032026) |
| 0.1 | 0.4 | GO:1900244 | positive regulation of synaptic vesicle endocytosis(GO:1900244) |
| 0.1 | 0.9 | GO:0045075 | interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075) |
| 0.1 | 1.2 | GO:1901096 | regulation of autophagosome maturation(GO:1901096) |
| 0.1 | 0.3 | GO:0098974 | postsynaptic actin cytoskeleton organization(GO:0098974) |
| 0.1 | 1.0 | GO:0033572 | transferrin transport(GO:0033572) |
| 0.1 | 7.8 | GO:0035725 | sodium ion transmembrane transport(GO:0035725) |
| 0.1 | 0.9 | GO:0071816 | tail-anchored membrane protein insertion into ER membrane(GO:0071816) |
| 0.1 | 0.8 | GO:0051534 | negative regulation of NFAT protein import into nucleus(GO:0051534) |
| 0.1 | 0.7 | GO:0031424 | keratinization(GO:0031424) |
| 0.1 | 0.8 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.1 | 1.8 | GO:0007193 | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193) |
| 0.1 | 1.8 | GO:0010666 | positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666) |
| 0.1 | 0.4 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
| 0.1 | 0.4 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
| 0.1 | 1.2 | GO:1901223 | negative regulation of NIK/NF-kappaB signaling(GO:1901223) |
| 0.1 | 0.3 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
| 0.1 | 0.4 | GO:0048739 | cardiac muscle fiber development(GO:0048739) |
| 0.1 | 0.5 | GO:0045919 | positive regulation of cytolysis(GO:0045919) |
| 0.1 | 2.9 | GO:0071526 | semaphorin-plexin signaling pathway(GO:0071526) |
| 0.1 | 0.3 | GO:0048209 | regulation of vesicle targeting, to, from or within Golgi(GO:0048209) |
| 0.1 | 2.1 | GO:0015813 | L-glutamate transport(GO:0015813) |
| 0.1 | 0.3 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860) |
| 0.1 | 2.3 | GO:0060716 | labyrinthine layer blood vessel development(GO:0060716) |
| 0.1 | 6.3 | GO:1903749 | positive regulation of establishment of protein localization to mitochondrion(GO:1903749) |
| 0.1 | 0.7 | GO:0000042 | protein targeting to Golgi(GO:0000042) |
| 0.1 | 0.7 | GO:0035520 | monoubiquitinated protein deubiquitination(GO:0035520) |
| 0.1 | 0.9 | GO:0001675 | acrosome assembly(GO:0001675) intermediate filament organization(GO:0045109) |
| 0.1 | 0.4 | GO:0003383 | apical constriction(GO:0003383) |
| 0.1 | 1.4 | GO:0086010 | membrane depolarization during action potential(GO:0086010) |
| 0.1 | 1.0 | GO:0006924 | activation-induced cell death of T cells(GO:0006924) |
| 0.1 | 1.6 | GO:0033235 | positive regulation of protein sumoylation(GO:0033235) |
| 0.1 | 0.4 | GO:0032364 | oxygen homeostasis(GO:0032364) |
| 0.1 | 0.2 | GO:0010989 | negative regulation of low-density lipoprotein particle clearance(GO:0010989) |
| 0.1 | 1.2 | GO:0036296 | cellular response to increased oxygen levels(GO:0036295) response to increased oxygen levels(GO:0036296) |
| 0.1 | 0.3 | GO:0072675 | osteoclast fusion(GO:0072675) |
| 0.1 | 1.4 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 0.1 | 1.5 | GO:1904355 | positive regulation of telomere capping(GO:1904355) |
| 0.1 | 0.8 | GO:0001682 | tRNA 5'-leader removal(GO:0001682) |
| 0.1 | 4.0 | GO:0061178 | regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178) |
| 0.1 | 2.7 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
| 0.1 | 0.3 | GO:1902775 | mitochondrial large ribosomal subunit assembly(GO:1902775) |
| 0.1 | 2.0 | GO:0061036 | positive regulation of cartilage development(GO:0061036) |
| 0.1 | 1.0 | GO:0008535 | respiratory chain complex IV assembly(GO:0008535) |
| 0.1 | 1.1 | GO:0045104 | intermediate filament cytoskeleton organization(GO:0045104) |
| 0.1 | 2.4 | GO:0006506 | GPI anchor biosynthetic process(GO:0006506) |
| 0.0 | 0.3 | GO:1902988 | macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) neurofibrillary tangle assembly(GO:1902988) regulation of neurofibrillary tangle assembly(GO:1902996) positive regulation of neurofibrillary tangle assembly(GO:1902998) |
| 0.0 | 0.2 | GO:0072429 | response to intra-S DNA damage checkpoint signaling(GO:0072429) |
| 0.0 | 0.2 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
| 0.0 | 0.8 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
| 0.0 | 1.0 | GO:0042755 | eating behavior(GO:0042755) |
| 0.0 | 3.0 | GO:0051453 | regulation of intracellular pH(GO:0051453) |
| 0.0 | 0.5 | GO:0009191 | ribonucleoside diphosphate catabolic process(GO:0009191) |
| 0.0 | 0.7 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
| 0.0 | 0.6 | GO:0080182 | histone H3-K4 trimethylation(GO:0080182) |
| 0.0 | 1.4 | GO:0045921 | positive regulation of exocytosis(GO:0045921) |
| 0.0 | 0.1 | GO:1901301 | regulation of cargo loading into COPII-coated vesicle(GO:1901301) |
| 0.0 | 0.7 | GO:0007030 | Golgi organization(GO:0007030) |
| 0.0 | 0.5 | GO:0019369 | arachidonic acid metabolic process(GO:0019369) |
| 0.0 | 2.9 | GO:0030048 | actin filament-based movement(GO:0030048) |
| 0.0 | 2.6 | GO:0006487 | protein N-linked glycosylation(GO:0006487) |
| 0.0 | 2.6 | GO:0071804 | cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805) |
| 0.0 | 0.1 | GO:0032792 | negative regulation of CREB transcription factor activity(GO:0032792) |
| 0.0 | 2.5 | GO:0006888 | ER to Golgi vesicle-mediated transport(GO:0006888) |
| 0.0 | 0.1 | GO:0014022 | neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) |
| 0.0 | 2.0 | GO:0009612 | response to mechanical stimulus(GO:0009612) |
| 0.0 | 0.2 | GO:0045351 | type I interferon biosynthetic process(GO:0045351) |
| 0.0 | 0.2 | GO:0007200 | phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200) |
| 0.0 | 0.1 | GO:0060265 | positive regulation of respiratory burst involved in inflammatory response(GO:0060265) |
| 0.0 | 0.4 | GO:0051131 | chaperone-mediated protein complex assembly(GO:0051131) |
| 0.0 | 0.6 | GO:0006879 | cellular iron ion homeostasis(GO:0006879) |
| 0.0 | 0.9 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.0 | 1.2 | GO:0030490 | maturation of SSU-rRNA(GO:0030490) |
| 0.0 | 0.2 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 0.0 | 0.2 | GO:1903214 | regulation of protein targeting to mitochondrion(GO:1903214) |
| 0.0 | 1.4 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.0 | 0.4 | GO:0044458 | motile cilium assembly(GO:0044458) |
| 0.0 | 0.4 | GO:0070266 | necroptotic process(GO:0070266) |
| 0.0 | 1.6 | GO:0031032 | actomyosin structure organization(GO:0031032) |
| 0.0 | 0.6 | GO:0035458 | cellular response to interferon-beta(GO:0035458) |
| 0.0 | 0.1 | GO:0015675 | nickel cation transport(GO:0015675) |
| 0.0 | 2.2 | GO:0008033 | tRNA processing(GO:0008033) |
| 0.0 | 2.6 | GO:0015711 | organic anion transport(GO:0015711) |
| 0.0 | 0.7 | GO:0042982 | amyloid precursor protein metabolic process(GO:0042982) |
| 0.0 | 2.0 | GO:0035023 | regulation of Rho protein signal transduction(GO:0035023) |
| 0.0 | 0.7 | GO:0051145 | smooth muscle cell differentiation(GO:0051145) |
| 0.0 | 0.0 | GO:0090063 | positive regulation of microtubule nucleation(GO:0090063) |
| 0.0 | 0.1 | GO:0010825 | positive regulation of centrosome duplication(GO:0010825) |
| 0.0 | 0.4 | GO:0097006 | regulation of plasma lipoprotein particle levels(GO:0097006) |
| 0.0 | 0.4 | GO:0061512 | protein localization to cilium(GO:0061512) |
| 0.0 | 0.0 | GO:0019074 | viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) |
| 0.0 | 0.5 | GO:0008543 | fibroblast growth factor receptor signaling pathway(GO:0008543) |
| 0.0 | 0.3 | GO:0032008 | positive regulation of TOR signaling(GO:0032008) |
| 0.0 | 2.1 | GO:0035264 | multicellular organism growth(GO:0035264) |
| 0.0 | 0.1 | GO:0044387 | negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387) |
| 0.0 | 0.4 | GO:0001658 | branching involved in ureteric bud morphogenesis(GO:0001658) |
| 0.0 | 0.2 | GO:0051491 | positive regulation of filopodium assembly(GO:0051491) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.0 | 20.3 | GO:0045298 | tubulin complex(GO:0045298) |
| 1.7 | 5.2 | GO:0098855 | HCN channel complex(GO:0098855) |
| 1.3 | 21.3 | GO:0043196 | varicosity(GO:0043196) |
| 1.3 | 6.3 | GO:0005683 | U7 snRNP(GO:0005683) |
| 1.1 | 2.2 | GO:0002142 | stereocilia ankle link complex(GO:0002142) |
| 1.1 | 5.4 | GO:0005784 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
| 1.0 | 5.0 | GO:0044316 | cone cell pedicle(GO:0044316) |
| 0.9 | 2.8 | GO:1990075 | kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075) |
| 0.9 | 6.8 | GO:0097433 | dense body(GO:0097433) |
| 0.8 | 2.3 | GO:0097233 | lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233) |
| 0.7 | 3.7 | GO:1990037 | Lewy body core(GO:1990037) |
| 0.7 | 10.2 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.6 | 2.5 | GO:1990769 | proximal neuron projection(GO:1990769) |
| 0.6 | 1.7 | GO:0048179 | activin receptor complex(GO:0048179) |
| 0.6 | 8.3 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.5 | 2.7 | GO:0038039 | G-protein coupled receptor heterodimeric complex(GO:0038039) |
| 0.5 | 2.9 | GO:0070776 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
| 0.5 | 2.4 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
| 0.5 | 2.3 | GO:1903440 | calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440) |
| 0.4 | 15.3 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
| 0.4 | 2.1 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
| 0.4 | 2.1 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 0.4 | 2.9 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.4 | 3.7 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
| 0.4 | 0.8 | GO:0031523 | Myb complex(GO:0031523) |
| 0.4 | 1.2 | GO:0034274 | Atg12-Atg5-Atg16 complex(GO:0034274) |
| 0.3 | 1.7 | GO:0070044 | synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044) |
| 0.3 | 4.9 | GO:0032039 | integrator complex(GO:0032039) |
| 0.3 | 1.5 | GO:0070876 | SOSS complex(GO:0070876) |
| 0.3 | 1.4 | GO:0071556 | integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553) |
| 0.3 | 2.3 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
| 0.2 | 4.2 | GO:0032279 | asymmetric synapse(GO:0032279) |
| 0.2 | 1.2 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.2 | 3.0 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.2 | 8.6 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.2 | 0.7 | GO:0070939 | Dsl1p complex(GO:0070939) |
| 0.2 | 2.4 | GO:0000812 | Swr1 complex(GO:0000812) |
| 0.2 | 0.6 | GO:0005965 | protein farnesyltransferase complex(GO:0005965) |
| 0.2 | 1.1 | GO:0097443 | sorting endosome(GO:0097443) |
| 0.2 | 0.9 | GO:0033063 | Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
| 0.2 | 2.1 | GO:0016600 | flotillin complex(GO:0016600) |
| 0.2 | 14.5 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.2 | 2.5 | GO:0030008 | TRAPP complex(GO:0030008) |
| 0.2 | 1.1 | GO:0044327 | dendritic spine head(GO:0044327) |
| 0.2 | 0.9 | GO:0000172 | ribonuclease MRP complex(GO:0000172) |
| 0.1 | 1.1 | GO:0060053 | neurofilament cytoskeleton(GO:0060053) |
| 0.1 | 6.4 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.1 | 2.8 | GO:0030673 | axolemma(GO:0030673) |
| 0.1 | 1.3 | GO:0090543 | ESCRT III complex(GO:0000815) Flemming body(GO:0090543) |
| 0.1 | 3.8 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.1 | 6.3 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.1 | 1.8 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.1 | 4.5 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.1 | 25.4 | GO:0070382 | exocytic vesicle(GO:0070382) |
| 0.1 | 7.0 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.1 | 0.7 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
| 0.1 | 3.4 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
| 0.1 | 0.5 | GO:1990131 | Iml1 complex(GO:1990130) Gtr1-Gtr2 GTPase complex(GO:1990131) |
| 0.1 | 0.5 | GO:1990246 | uniplex complex(GO:1990246) |
| 0.1 | 18.7 | GO:0098852 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
| 0.1 | 1.1 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 0.1 | 0.9 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.1 | 1.2 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.1 | 4.1 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.1 | 1.0 | GO:0030137 | COPI-coated vesicle(GO:0030137) |
| 0.1 | 1.5 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.1 | 0.1 | GO:0071986 | Ragulator complex(GO:0071986) |
| 0.1 | 1.0 | GO:0055037 | recycling endosome(GO:0055037) |
| 0.1 | 0.4 | GO:0097361 | CIA complex(GO:0097361) |
| 0.1 | 0.4 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 0.1 | 0.5 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 0.1 | 0.9 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 0.1 | 9.1 | GO:0045211 | postsynaptic membrane(GO:0045211) |
| 0.1 | 9.8 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.1 | 0.2 | GO:0048476 | Holliday junction resolvase complex(GO:0048476) |
| 0.1 | 1.1 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.1 | 0.7 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.1 | 11.1 | GO:0000139 | Golgi membrane(GO:0000139) |
| 0.1 | 3.6 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.0 | 0.3 | GO:0097418 | neurofibrillary tangle(GO:0097418) |
| 0.0 | 4.1 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.0 | 2.8 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 0.7 | GO:0005797 | Golgi medial cisterna(GO:0005797) |
| 0.0 | 1.7 | GO:0005684 | U2-type spliceosomal complex(GO:0005684) |
| 0.0 | 1.0 | GO:0005865 | striated muscle thin filament(GO:0005865) |
| 0.0 | 0.3 | GO:0034704 | calcium channel complex(GO:0034704) |
| 0.0 | 0.2 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
| 0.0 | 0.9 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.0 | 30.8 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
| 0.0 | 9.3 | GO:0005764 | lytic vacuole(GO:0000323) lysosome(GO:0005764) |
| 0.0 | 1.1 | GO:0032040 | small-subunit processome(GO:0032040) |
| 0.0 | 1.3 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.0 | 0.3 | GO:0031931 | TORC1 complex(GO:0031931) |
| 0.0 | 1.2 | GO:0005776 | autophagosome(GO:0005776) |
| 0.0 | 0.3 | GO:0002102 | podosome(GO:0002102) |
| 0.0 | 1.6 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.0 | 0.2 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.0 | 2.4 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 0.0 | 0.1 | GO:1990909 | Wnt signalosome(GO:1990909) |
| 0.0 | 0.9 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.0 | 0.4 | GO:0070069 | cytochrome complex(GO:0070069) |
| 0.0 | 5.9 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.0 | 0.6 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.0 | 0.2 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.0 | 0.1 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 0.0 | 0.5 | GO:0030136 | clathrin-coated vesicle(GO:0030136) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.6 | 10.9 | GO:0003989 | acetyl-CoA carboxylase activity(GO:0003989) |
| 2.9 | 20.3 | GO:0099609 | microtubule lateral binding(GO:0099609) |
| 2.6 | 10.2 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
| 2.5 | 7.6 | GO:0004574 | oligo-1,6-glucosidase activity(GO:0004574) |
| 2.4 | 23.7 | GO:0031749 | D2 dopamine receptor binding(GO:0031749) |
| 2.1 | 6.3 | GO:0071209 | U7 snRNA binding(GO:0071209) |
| 2.1 | 8.2 | GO:0003976 | UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976) |
| 1.1 | 4.5 | GO:0008332 | low voltage-gated calcium channel activity(GO:0008332) |
| 1.0 | 4.2 | GO:0001602 | pancreatic polypeptide receptor activity(GO:0001602) |
| 0.9 | 4.4 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
| 0.9 | 7.7 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.8 | 2.5 | GO:0022833 | mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833) |
| 0.8 | 6.9 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
| 0.8 | 3.0 | GO:0035473 | lipase binding(GO:0035473) |
| 0.7 | 6.7 | GO:0003873 | 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) |
| 0.7 | 1.4 | GO:0004936 | alpha-adrenergic receptor activity(GO:0004936) epinephrine binding(GO:0051379) |
| 0.6 | 4.2 | GO:0001609 | G-protein coupled adenosine receptor activity(GO:0001609) heterotrimeric G-protein binding(GO:0032795) |
| 0.6 | 2.4 | GO:0004663 | Rab geranylgeranyltransferase activity(GO:0004663) |
| 0.6 | 1.7 | GO:0019107 | glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107) |
| 0.6 | 10.2 | GO:0005248 | voltage-gated sodium channel activity(GO:0005248) |
| 0.6 | 2.2 | GO:0051377 | mannose-ethanolamine phosphotransferase activity(GO:0051377) |
| 0.5 | 2.2 | GO:0034511 | U3 snoRNA binding(GO:0034511) |
| 0.5 | 1.6 | GO:0003986 | acetyl-CoA hydrolase activity(GO:0003986) |
| 0.5 | 0.5 | GO:0031750 | D3 dopamine receptor binding(GO:0031750) |
| 0.5 | 6.7 | GO:0001618 | virus receptor activity(GO:0001618) |
| 0.5 | 1.5 | GO:0004449 | isocitrate dehydrogenase (NAD+) activity(GO:0004449) |
| 0.5 | 2.3 | GO:0097643 | amylin receptor activity(GO:0097643) |
| 0.4 | 2.7 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
| 0.4 | 1.3 | GO:0001888 | glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888) |
| 0.4 | 1.7 | GO:0016361 | activin receptor activity, type I(GO:0016361) |
| 0.4 | 1.7 | GO:0005483 | soluble NSF attachment protein activity(GO:0005483) |
| 0.4 | 1.2 | GO:0004450 | isocitrate dehydrogenase (NADP+) activity(GO:0004450) |
| 0.4 | 1.1 | GO:0047751 | 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751) |
| 0.4 | 1.1 | GO:0015173 | hydrogen:amino acid symporter activity(GO:0005280) aromatic amino acid transmembrane transporter activity(GO:0015173) |
| 0.4 | 3.2 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.3 | 1.6 | GO:0004028 | 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) |
| 0.3 | 0.9 | GO:0000386 | second spliceosomal transesterification activity(GO:0000386) |
| 0.3 | 0.6 | GO:0004660 | protein farnesyltransferase activity(GO:0004660) |
| 0.3 | 3.9 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.3 | 2.1 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.3 | 1.0 | GO:0071987 | WD40-repeat domain binding(GO:0071987) |
| 0.3 | 1.0 | GO:0005008 | hepatocyte growth factor-activated receptor activity(GO:0005008) |
| 0.3 | 4.8 | GO:0034483 | heparan sulfate sulfotransferase activity(GO:0034483) |
| 0.3 | 1.8 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
| 0.2 | 1.7 | GO:0015198 | oligopeptide transporter activity(GO:0015198) |
| 0.2 | 6.8 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.2 | 1.2 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
| 0.2 | 1.1 | GO:0030144 | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144) |
| 0.2 | 7.8 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.2 | 2.9 | GO:0023026 | MHC class II protein complex binding(GO:0023026) |
| 0.2 | 1.2 | GO:0003831 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831) |
| 0.2 | 1.5 | GO:0035033 | histone deacetylase regulator activity(GO:0035033) |
| 0.2 | 1.3 | GO:0051731 | polynucleotide 5'-hydroxyl-kinase activity(GO:0051731) |
| 0.2 | 3.4 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.2 | 1.7 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 0.2 | 11.2 | GO:0001540 | beta-amyloid binding(GO:0001540) |
| 0.2 | 1.3 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.2 | 1.3 | GO:0008242 | omega peptidase activity(GO:0008242) |
| 0.2 | 2.9 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.2 | 3.9 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.2 | 1.6 | GO:0044548 | S100 protein binding(GO:0044548) |
| 0.2 | 1.4 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
| 0.2 | 2.1 | GO:0005314 | high-affinity glutamate transmembrane transporter activity(GO:0005314) |
| 0.2 | 6.7 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
| 0.2 | 0.8 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
| 0.1 | 1.4 | GO:0031005 | filamin binding(GO:0031005) |
| 0.1 | 0.8 | GO:0004791 | thioredoxin-disulfide reductase activity(GO:0004791) |
| 0.1 | 0.9 | GO:0000150 | recombinase activity(GO:0000150) |
| 0.1 | 1.0 | GO:0016308 | 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308) |
| 0.1 | 2.0 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.1 | 0.5 | GO:0008853 | exodeoxyribonuclease III activity(GO:0008853) |
| 0.1 | 4.8 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.1 | 1.6 | GO:0002161 | aminoacyl-tRNA editing activity(GO:0002161) |
| 0.1 | 0.8 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
| 0.1 | 1.5 | GO:0098505 | G-rich strand telomeric DNA binding(GO:0098505) |
| 0.1 | 0.3 | GO:0098973 | structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973) |
| 0.1 | 5.0 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.1 | 1.4 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
| 0.1 | 0.4 | GO:0033142 | progesterone receptor binding(GO:0033142) |
| 0.1 | 0.6 | GO:0043426 | MRF binding(GO:0043426) |
| 0.1 | 1.2 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
| 0.1 | 0.8 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 0.1 | 0.6 | GO:0035251 | UDP-glucosyltransferase activity(GO:0035251) |
| 0.1 | 0.6 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
| 0.1 | 10.4 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.1 | 3.4 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.1 | 0.3 | GO:0005219 | ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763) |
| 0.1 | 0.5 | GO:0016215 | acyl-CoA desaturase activity(GO:0016215) |
| 0.1 | 6.2 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.1 | 2.6 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.1 | 7.4 | GO:0042626 | ATPase activity, coupled to transmembrane movement of substances(GO:0042626) |
| 0.1 | 1.5 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.1 | 1.6 | GO:0017110 | nucleoside-diphosphatase activity(GO:0017110) |
| 0.1 | 3.5 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.1 | 8.0 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.1 | 0.4 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
| 0.1 | 0.8 | GO:0004526 | ribonuclease P activity(GO:0004526) |
| 0.1 | 1.0 | GO:0019215 | intermediate filament binding(GO:0019215) |
| 0.1 | 0.3 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 0.1 | 1.7 | GO:0008376 | acetylgalactosaminyltransferase activity(GO:0008376) |
| 0.1 | 6.6 | GO:0051117 | ATPase binding(GO:0051117) |
| 0.1 | 0.4 | GO:0004673 | phosphorelay sensor kinase activity(GO:0000155) protein histidine kinase activity(GO:0004673) |
| 0.1 | 0.4 | GO:0047184 | 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) |
| 0.1 | 3.1 | GO:0017022 | myosin binding(GO:0017022) |
| 0.1 | 0.3 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.1 | 2.3 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.1 | 4.3 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 0.2 | GO:0000832 | inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724) |
| 0.0 | 0.9 | GO:0001671 | ATPase activator activity(GO:0001671) |
| 0.0 | 2.7 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
| 0.0 | 0.4 | GO:0035368 | selenocysteine insertion sequence binding(GO:0035368) |
| 0.0 | 13.0 | GO:0030695 | GTPase regulator activity(GO:0030695) |
| 0.0 | 1.9 | GO:0097110 | scaffold protein binding(GO:0097110) |
| 0.0 | 0.4 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.0 | 0.2 | GO:0008821 | crossover junction endodeoxyribonuclease activity(GO:0008821) |
| 0.0 | 3.7 | GO:0051219 | phosphoprotein binding(GO:0051219) |
| 0.0 | 0.3 | GO:0015288 | porin activity(GO:0015288) |
| 0.0 | 3.1 | GO:0016247 | channel regulator activity(GO:0016247) |
| 0.0 | 0.8 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.0 | 0.7 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
| 0.0 | 3.2 | GO:0043130 | ubiquitin binding(GO:0043130) |
| 0.0 | 3.2 | GO:0002020 | protease binding(GO:0002020) |
| 0.0 | 2.0 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.0 | 0.4 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.0 | 0.1 | GO:0033192 | calmodulin-dependent protein phosphatase activity(GO:0033192) |
| 0.0 | 0.5 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
| 0.0 | 1.4 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 0.1 | GO:0015099 | nickel cation transmembrane transporter activity(GO:0015099) |
| 0.0 | 0.4 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.0 | 0.6 | GO:0005496 | steroid binding(GO:0005496) |
| 0.0 | 1.0 | GO:0005262 | calcium channel activity(GO:0005262) |
| 0.0 | 0.2 | GO:0005234 | extracellular-glutamate-gated ion channel activity(GO:0005234) |
| 0.0 | 0.8 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.0 | 1.0 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 0.1 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.0 | 0.2 | GO:0008188 | neuropeptide receptor activity(GO:0008188) |
| 0.0 | 0.3 | GO:0008236 | serine-type peptidase activity(GO:0008236) |
| 0.0 | 0.6 | GO:0005249 | voltage-gated potassium channel activity(GO:0005249) |
| 0.0 | 0.1 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 0.0 | 0.4 | GO:0004521 | endoribonuclease activity(GO:0004521) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 15.3 | PID_RHODOPSIN_PATHWAY | Visual signal transduction: Rods |
| 1.1 | 20.3 | PID_P38_GAMMA_DELTA_PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.5 | 22.1 | PID_EPHRINB_REV_PATHWAY | Ephrin B reverse signaling |
| 0.4 | 5.7 | PID_ERBB_NETWORK_PATHWAY | ErbB receptor signaling network |
| 0.3 | 9.6 | PID_NECTIN_PATHWAY | Nectin adhesion pathway |
| 0.3 | 10.4 | PID_REELIN_PATHWAY | Reelin signaling pathway |
| 0.2 | 2.7 | PID_LPA4_PATHWAY | LPA4-mediated signaling events |
| 0.2 | 5.1 | PID_NCADHERIN_PATHWAY | N-cadherin signaling events |
| 0.2 | 1.7 | PID_ALK2_PATHWAY | ALK2 signaling events |
| 0.2 | 3.5 | SA_CASPASE_CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.2 | 9.5 | PID_HES_HEY_PATHWAY | Notch-mediated HES/HEY network |
| 0.1 | 1.8 | PID_S1P_S1P4_PATHWAY | S1P4 pathway |
| 0.1 | 8.6 | PID_RAC1_REG_PATHWAY | Regulation of RAC1 activity |
| 0.1 | 1.3 | PID_CXCR4_PATHWAY | CXCR4-mediated signaling events |
| 0.1 | 3.9 | PID_SHP2_PATHWAY | SHP2 signaling |
| 0.1 | 6.4 | PID_HIF1_TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.1 | 12.5 | PID_P53_DOWNSTREAM_PATHWAY | Direct p53 effectors |
| 0.1 | 1.2 | PID_PTP1B_PATHWAY | Signaling events mediated by PTP1B |
| 0.1 | 2.5 | PID_AJDISS_2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.1 | 2.2 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
| 0.1 | 7.9 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 1.1 | PID_HEDGEHOG_2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.0 | 6.3 | NABA_SECRETED_FACTORS | Genes encoding secreted soluble factors |
| 0.0 | 2.4 | PID_CMYB_PATHWAY | C-MYB transcription factor network |
| 0.0 | 3.6 | NABA_MATRISOME_ASSOCIATED | Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors |
| 0.0 | 1.5 | PID_ERA_GENOMIC_PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 0.4 | PID_CD40_PATHWAY | CD40/CD40L signaling |
| 0.0 | 0.8 | PID_FAS_PATHWAY | FAS (CD95) signaling pathway |
| 0.0 | 0.3 | PID_CXCR3_PATHWAY | CXCR3-mediated signaling events |
| 0.0 | 0.9 | PID_RAC1_PATHWAY | RAC1 signaling pathway |
| 0.0 | 0.2 | PID_IFNG_PATHWAY | IFN-gamma pathway |
| 0.0 | 0.4 | PID_TRKR_PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 20.3 | REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.9 | 16.2 | REACTOME_GAP_JUNCTION_DEGRADATION | Genes involved in Gap junction degradation |
| 0.5 | 10.8 | REACTOME_CRMPS_IN_SEMA3A_SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.5 | 1.0 | REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS | Genes involved in Eicosanoid ligand-binding receptors |
| 0.4 | 9.2 | REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.3 | 8.3 | REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII | Genes involved in CREB phosphorylation through the activation of CaMKII |
| 0.3 | 4.2 | REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS | Genes involved in Nucleotide-like (purinergic) receptors |
| 0.3 | 8.0 | REACTOME_NEPHRIN_INTERACTIONS | Genes involved in Nephrin interactions |
| 0.3 | 10.9 | REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS | Genes involved in Fatty Acyl-CoA Biosynthesis |
| 0.3 | 2.1 | REACTOME_ARMS_MEDIATED_ACTIVATION | Genes involved in ARMS-mediated activation |
| 0.3 | 1.7 | REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING | Genes involved in Spry regulation of FGF signaling |
| 0.2 | 2.6 | REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
| 0.2 | 2.8 | REACTOME_ACTIVATION_OF_RAC | Genes involved in Activation of Rac |
| 0.2 | 5.7 | REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
| 0.2 | 3.5 | REACTOME_HYALURONAN_METABOLISM | Genes involved in Hyaluronan metabolism |
| 0.2 | 1.1 | REACTOME_ANDROGEN_BIOSYNTHESIS | Genes involved in Androgen biosynthesis |
| 0.2 | 4.8 | REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.2 | 1.6 | REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS | Genes involved in Tandem pore domain potassium channels |
| 0.2 | 2.9 | REACTOME_PLATELET_CALCIUM_HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.2 | 1.7 | REACTOME_TRANSPORT_OF_ORGANIC_ANIONS | Genes involved in Transport of organic anions |
| 0.2 | 6.7 | REACTOME_TIGHT_JUNCTION_INTERACTIONS | Genes involved in Tight junction interactions |
| 0.2 | 2.7 | REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.2 | 3.9 | REACTOME_FRS2_MEDIATED_CASCADE | Genes involved in FRS2-mediated cascade |
| 0.2 | 3.4 | REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.2 | 1.0 | REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
| 0.2 | 6.7 | REACTOME_GLYCOLYSIS | Genes involved in Glycolysis |
| 0.2 | 2.2 | REACTOME_P38MAPK_EVENTS | Genes involved in p38MAPK events |
| 0.2 | 2.0 | REACTOME_HDL_MEDIATED_LIPID_TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.2 | 11.2 | REACTOME_POTASSIUM_CHANNELS | Genes involved in Potassium Channels |
| 0.1 | 4.4 | REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.1 | 2.7 | REACTOME_ERK_MAPK_TARGETS | Genes involved in ERK/MAPK targets |
| 0.1 | 9.9 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | Genes involved in NRAGE signals death through JNK |
| 0.1 | 1.7 | REACTOME_INFLAMMASOMES | Genes involved in Inflammasomes |
| 0.1 | 4.8 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.1 | 15.3 | REACTOME_G_ALPHA_I_SIGNALLING_EVENTS | Genes involved in G alpha (i) signalling events |
| 0.1 | 4.5 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.1 | 2.4 | REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.1 | 1.8 | REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.1 | 0.9 | REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 0.1 | 1.6 | REACTOME_INSULIN_RECEPTOR_RECYCLING | Genes involved in Insulin receptor recycling |
| 0.1 | 1.9 | REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.1 | 1.5 | REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.1 | 1.2 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.1 | 2.2 | REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
| 0.1 | 1.7 | REACTOME_MYOGENESIS | Genes involved in Myogenesis |
| 0.1 | 1.2 | REACTOME_PEROXISOMAL_LIPID_METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.1 | 5.9 | REACTOME_SIGNALING_BY_RHO_GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.0 | 1.4 | REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING | Genes involved in Sema4D in semaphorin signaling |
| 0.0 | 1.1 | REACTOME_CA_DEPENDENT_EVENTS | Genes involved in Ca-dependent events |
| 0.0 | 1.4 | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.0 | 0.5 | REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
| 0.0 | 4.5 | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.0 | 2.1 | REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.0 | 0.4 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PS | Genes involved in Acyl chain remodelling of PS |
| 0.0 | 0.6 | REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 0.0 | 0.7 | REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.0 | 0.7 | REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.0 | 1.3 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.0 | 0.2 | REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS | Genes involved in Phosphorylation of CD3 and TCR zeta chains |
| 0.0 | 0.3 | REACTOME_MTORC1_MEDIATED_SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.0 | 0.5 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.0 | 1.3 | REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.0 | 0.6 | REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION | Genes involved in Asparagine N-linked glycosylation |
| 0.0 | 0.2 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.0 | 0.2 | REACTOME_RNA_POL_III_CHAIN_ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
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