Motif ID: Dbp

Z-value: 0.883


Transcription factors associated with Dbp:

Gene SymbolEntrez IDGene Name
Dbp ENSMUSG00000059824.4 Dbp

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Dbpmm10_v2_chr7_+_45705518_45705624-0.256.2e-02Click!


Activity profile for motif Dbp.

activity profile for motif Dbp


Sorted Z-values histogram for motif Dbp

Sorted Z-values for motif Dbp



Network of associatons between targets according to the STRING database.



First level regulatory network of Dbp

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_123264076 10.932 ENSMUST00000050756.7
 Fam19a2
family with sequence similarity 19, member A2
chr5_+_150259922 7.077 ENSMUST00000087204.5
 Fry
furry homolog (Drosophila)
chr16_+_7069825 6.889 ENSMUST00000056416.7
 Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr3_-_26133734 6.725 ENSMUST00000108308.3
ENSMUST00000075054.4
 Nlgn1

neuroligin 1

chr1_+_66386968 6.505 ENSMUST00000145419.1
 Map2
microtubule-associated protein 2
chr10_+_85386813 6.486 ENSMUST00000105307.1
ENSMUST00000020231.3
 Btbd11

BTB (POZ) domain containing 11

chr5_-_44799643 5.535 ENSMUST00000070748.5
 Ldb2
LIM domain binding 2
chr6_-_91807424 5.332 ENSMUST00000162300.1
 Grip2
glutamate receptor interacting protein 2
chrX_-_165327376 5.187 ENSMUST00000058787.8
 Glra2
glycine receptor, alpha 2 subunit
chr19_-_28911879 5.150 ENSMUST00000179171.1
 AC163993.1
AC163993.1
chr5_-_92042630 5.113 ENSMUST00000113140.1
ENSMUST00000113143.1
 Cdkl2

cyclin-dependent kinase-like 2 (CDC2-related kinase)

chr12_+_61523889 5.098 ENSMUST00000119481.1
ENSMUST00000055815.7
 Lrfn5

leucine rich repeat and fibronectin type III domain containing 5

chr6_-_91807318 4.965 ENSMUST00000159684.1
 Grip2
glutamate receptor interacting protein 2
chr2_+_65845833 4.964 ENSMUST00000053910.3
 Csrnp3
cysteine-serine-rich nuclear protein 3
chr14_-_102982630 4.878 ENSMUST00000184744.1
 KCTD12
mmu-mir-5130
chr8_+_54954728 4.784 ENSMUST00000033915.7
 Gpm6a
glycoprotein m6a
chr9_-_49798905 4.692 ENSMUST00000114476.2
 Ncam1
neural cell adhesion molecule 1
chrX_-_43167817 4.550 ENSMUST00000115058.1
ENSMUST00000115059.1
 Tenm1

teneurin transmembrane protein 1

chr10_-_64090265 4.406 ENSMUST00000105439.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr9_-_49798729 4.357 ENSMUST00000166811.2
 Ncam1
neural cell adhesion molecule 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 125 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 13.6 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.2 12.7 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.7 11.3 GO:1902993 positive regulation of amyloid precursor protein catabolic process(GO:1902993)
1.0 10.3 GO:0014824 artery smooth muscle contraction(GO:0014824)
0.1 10.0 GO:0007416 synapse assembly(GO:0007416)
3.1 9.2 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923)
3.0 9.0 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.1 7.7 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.8 7.5 GO:0071420 cellular response to histamine(GO:0071420)
0.8 7.1 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.4 6.8 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.4 6.4 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.1 6.4 GO:0034605 cellular response to heat(GO:0034605)
0.1 6.3 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.8 6.2 GO:0061368 maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.1 6.2 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.7 6.0 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.3 5.5 GO:0010669 epithelial structure maintenance(GO:0010669)
1.8 5.4 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.9 5.2 GO:0060012 synaptic transmission, glycinergic(GO:0060012)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 61 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 43.6 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 21.2 GO:0030427 site of polarized growth(GO:0030427)
0.6 14.2 GO:0071565 nBAF complex(GO:0071565)
0.8 11.7 GO:1902711 GABA-A receptor complex(GO:1902711)
0.2 10.1 GO:0044295 axonal growth cone(GO:0044295)
0.5 9.7 GO:0032279 asymmetric synapse(GO:0032279)
0.4 7.9 GO:0032433 filopodium tip(GO:0032433)
0.2 7.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 7.0 GO:0005802 trans-Golgi network(GO:0005802)
0.7 6.5 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 6.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 5.3 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.2 5.2 GO:0034707 chloride channel complex(GO:0034707)
1.0 4.0 GO:0031673 H zone(GO:0031673)
0.1 3.1 GO:0035371 microtubule plus-end(GO:0035371)
0.3 2.9 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.5 2.7 GO:0032437 cuticular plate(GO:0032437)
0.0 2.6 GO:0036064 ciliary basal body(GO:0036064)
0.0 2.6 GO:0000139 Golgi membrane(GO:0000139)
0.8 2.5 GO:0098855 HCN channel complex(GO:0098855)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 99 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 16.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 10.1 GO:0035254 glutamate receptor binding(GO:0035254)
0.6 9.2 GO:0045499 chemorepellent activity(GO:0045499)
0.5 9.0 GO:0030275 LRR domain binding(GO:0030275)
0.0 8.1 GO:0005509 calcium ion binding(GO:0005509)
0.5 7.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.4 6.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.8 6.5 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.5 6.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 6.4 GO:0005516 calmodulin binding(GO:0005516)
0.9 6.0 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.6 5.5 GO:0030274 LIM domain binding(GO:0030274)
0.1 5.3 GO:0004860 protein kinase inhibitor activity(GO:0004860)
1.7 5.2 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.9 5.2 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.1 5.1 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
1.2 4.6 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 4.6 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.1 4.4 GO:0005262 calcium channel activity(GO:0005262)
0.9 4.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 9.3 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.1 9.0 PID_FGF_PATHWAY FGF signaling pathway
0.1 6.6 PID_LKB1_PATHWAY LKB1 signaling events
0.2 6.2 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.1 5.2 ST_ADRENERGIC Adrenergic Pathway
0.1 4.2 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 3.7 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 2.6 PID_CMYB_PATHWAY C-MYB transcription factor network
0.1 2.4 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.1 2.3 PID_SHP2_PATHWAY SHP2 signaling
0.0 2.2 PID_ERBB1_DOWNSTREAM_PATHWAY ErbB1 downstream signaling
0.0 2.0 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.1 1.9 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 1.8 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.6 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.5 PID_PLK1_PATHWAY PLK1 signaling events
0.1 1.1 PID_GMCSF_PATHWAY GMCSF-mediated signaling events
0.0 1.1 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 1.0 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.9 PID_CDC42_PATHWAY CDC42 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 16.9 REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT Genes involved in Ligand-gated ion channel transport
0.7 16.3 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.2 9.7 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 8.3 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.4 6.9 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.2 4.8 REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.1 4.4 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.2 4.0 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 3.5 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.1 3.5 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 3.5 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 3.1 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.2 2.7 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.2 2.7 REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH Genes involved in NCAM signaling for neurite out-growth
0.2 2.5 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 2.5 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.2 2.4 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.9 REACTOME_GRB2_EVENTS_IN_ERBB2_SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 1.4 REACTOME_ION_CHANNEL_TRANSPORT Genes involved in Ion channel transport
0.1 1.2 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism