Motif ID: Dmc1
Z-value: 1.114
Transcription factors associated with Dmc1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Dmc1 | ENSMUSG00000022429.10 | Dmc1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Dmc1 | mm10_v2_chr15_-_79605084_79605114 | 0.13 | 3.6e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 4.8 | GO:0051464 | positive regulation of cortisol secretion(GO:0051464) |
| 1.4 | 5.4 | GO:0038145 | macrophage colony-stimulating factor signaling pathway(GO:0038145) |
| 1.3 | 5.0 | GO:0006710 | androgen catabolic process(GO:0006710) |
| 0.9 | 4.5 | GO:0048245 | eosinophil chemotaxis(GO:0048245) |
| 0.9 | 2.7 | GO:0050925 | negative regulation of negative chemotaxis(GO:0050925) |
| 0.8 | 2.3 | GO:0016998 | cell wall macromolecule catabolic process(GO:0016998) |
| 0.7 | 3.6 | GO:1902683 | regulation of receptor localization to synapse(GO:1902683) |
| 0.6 | 1.8 | GO:0090526 | regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526) |
| 0.5 | 1.4 | GO:0042196 | dichloromethane metabolic process(GO:0018900) chlorinated hydrocarbon metabolic process(GO:0042196) halogenated hydrocarbon metabolic process(GO:0042197) |
| 0.5 | 3.8 | GO:0098707 | ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707) |
| 0.5 | 1.8 | GO:1901475 | pyruvate transmembrane transport(GO:1901475) |
| 0.4 | 1.8 | GO:0034441 | plasma lipoprotein particle oxidation(GO:0034441) |
| 0.4 | 1.8 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
| 0.3 | 6.6 | GO:0002495 | antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) |
| 0.3 | 1.7 | GO:0097167 | circadian regulation of translation(GO:0097167) |
| 0.3 | 1.9 | GO:0000050 | urea cycle(GO:0000050) urea metabolic process(GO:0019627) |
| 0.3 | 1.0 | GO:0002182 | cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248) |
| 0.3 | 1.6 | GO:0010025 | wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166) |
| 0.3 | 1.9 | GO:0050861 | positive regulation of B cell receptor signaling pathway(GO:0050861) |
| 0.3 | 3.4 | GO:0010650 | positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
| 0.3 | 0.9 | GO:0016056 | rhodopsin mediated signaling pathway(GO:0016056) |
| 0.3 | 1.2 | GO:0090467 | L-arginine import(GO:0043091) arginine import(GO:0090467) |
| 0.3 | 4.4 | GO:0033623 | regulation of integrin activation(GO:0033623) |
| 0.3 | 1.2 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
| 0.3 | 2.0 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 0.3 | 0.9 | GO:2001187 | positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187) |
| 0.3 | 8.3 | GO:0018345 | protein palmitoylation(GO:0018345) |
| 0.3 | 1.4 | GO:0072143 | mesangial cell differentiation(GO:0072007) mesangial cell development(GO:0072143) |
| 0.3 | 1.1 | GO:0019355 | nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628) |
| 0.3 | 1.6 | GO:1903795 | regulation of inorganic anion transmembrane transport(GO:1903795) |
| 0.3 | 1.3 | GO:0035426 | extracellular matrix-cell signaling(GO:0035426) |
| 0.2 | 1.0 | GO:0097494 | positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944) regulation of vesicle size(GO:0097494) |
| 0.2 | 0.7 | GO:0070649 | meiotic chromosome movement towards spindle pole(GO:0016344) formin-nucleated actin cable assembly(GO:0070649) |
| 0.2 | 2.6 | GO:0046512 | sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520) |
| 0.2 | 0.9 | GO:0002457 | T cell antigen processing and presentation(GO:0002457) |
| 0.2 | 3.0 | GO:0045741 | positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) |
| 0.2 | 2.4 | GO:2001135 | regulation of endocytic recycling(GO:2001135) |
| 0.2 | 1.7 | GO:1901162 | serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162) |
| 0.2 | 2.9 | GO:0010447 | response to acidic pH(GO:0010447) |
| 0.2 | 7.1 | GO:0071353 | cellular response to interleukin-4(GO:0071353) |
| 0.2 | 0.6 | GO:0071336 | regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338) |
| 0.2 | 1.2 | GO:0051096 | positive regulation of helicase activity(GO:0051096) |
| 0.2 | 1.0 | GO:0006543 | glutamine catabolic process(GO:0006543) |
| 0.2 | 0.5 | GO:0015910 | peroxisomal long-chain fatty acid import(GO:0015910) |
| 0.2 | 1.2 | GO:0019348 | dolichol metabolic process(GO:0019348) |
| 0.2 | 0.9 | GO:0097343 | ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026) |
| 0.2 | 0.5 | GO:0006295 | nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295) |
| 0.2 | 0.8 | GO:0015803 | branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820) |
| 0.2 | 1.4 | GO:0070072 | vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
| 0.2 | 0.5 | GO:0051771 | negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) |
| 0.2 | 1.6 | GO:0031053 | primary miRNA processing(GO:0031053) |
| 0.2 | 1.8 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
| 0.2 | 2.7 | GO:0006054 | N-acetylneuraminate metabolic process(GO:0006054) |
| 0.2 | 0.5 | GO:0034241 | positive regulation of macrophage fusion(GO:0034241) regulation of osteoclast proliferation(GO:0090289) |
| 0.1 | 0.6 | GO:0000019 | regulation of mitotic recombination(GO:0000019) telomeric 3' overhang formation(GO:0031860) |
| 0.1 | 0.6 | GO:1901740 | negative regulation of myoblast fusion(GO:1901740) |
| 0.1 | 1.3 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.1 | 1.2 | GO:0031848 | protection from non-homologous end joining at telomere(GO:0031848) |
| 0.1 | 0.3 | GO:1902527 | positive regulation of protein monoubiquitination(GO:1902527) |
| 0.1 | 1.5 | GO:1900113 | negative regulation of histone H3-K9 trimethylation(GO:1900113) |
| 0.1 | 1.8 | GO:0070842 | aggresome assembly(GO:0070842) |
| 0.1 | 0.4 | GO:0006011 | UDP-glucose metabolic process(GO:0006011) |
| 0.1 | 0.7 | GO:0052428 | modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428) |
| 0.1 | 0.4 | GO:0008355 | olfactory learning(GO:0008355) |
| 0.1 | 0.7 | GO:0034983 | peptidyl-lysine deacetylation(GO:0034983) negative regulation of protein targeting to mitochondrion(GO:1903215) |
| 0.1 | 0.8 | GO:0006590 | thyroid hormone generation(GO:0006590) |
| 0.1 | 0.6 | GO:0090292 | nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292) |
| 0.1 | 0.5 | GO:0046519 | sphingoid metabolic process(GO:0046519) |
| 0.1 | 0.8 | GO:2000819 | regulation of nucleotide-excision repair(GO:2000819) |
| 0.1 | 1.6 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.1 | 2.0 | GO:2000310 | regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310) |
| 0.1 | 1.1 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 0.1 | 0.5 | GO:0018307 | tRNA wobble position uridine thiolation(GO:0002143) enzyme active site formation(GO:0018307) |
| 0.1 | 0.8 | GO:0002098 | tRNA wobble uridine modification(GO:0002098) |
| 0.1 | 0.6 | GO:0048170 | positive regulation of long-term neuronal synaptic plasticity(GO:0048170) |
| 0.1 | 1.1 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 0.1 | 0.5 | GO:0044861 | protein transport into plasma membrane raft(GO:0044861) |
| 0.1 | 0.3 | GO:0071963 | establishment or maintenance of cell polarity regulating cell shape(GO:0071963) |
| 0.1 | 4.0 | GO:0035458 | cellular response to interferon-beta(GO:0035458) |
| 0.1 | 0.7 | GO:0016185 | synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) |
| 0.1 | 1.2 | GO:0097067 | cellular response to thyroid hormone stimulus(GO:0097067) |
| 0.1 | 0.3 | GO:0051030 | snRNA transport(GO:0051030) |
| 0.1 | 0.8 | GO:0035428 | hexose transmembrane transport(GO:0035428) |
| 0.1 | 0.1 | GO:0002925 | positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925) |
| 0.1 | 0.3 | GO:0071211 | protein targeting to vacuole involved in autophagy(GO:0071211) |
| 0.1 | 0.5 | GO:0035469 | determination of pancreatic left/right asymmetry(GO:0035469) |
| 0.1 | 14.9 | GO:0007416 | synapse assembly(GO:0007416) |
| 0.1 | 1.6 | GO:0036010 | protein localization to endosome(GO:0036010) |
| 0.1 | 0.6 | GO:0030382 | sperm mitochondrion organization(GO:0030382) |
| 0.1 | 1.4 | GO:0060219 | camera-type eye photoreceptor cell differentiation(GO:0060219) |
| 0.1 | 1.2 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 0.1 | 1.2 | GO:0043249 | erythrocyte maturation(GO:0043249) |
| 0.1 | 2.5 | GO:0043171 | peptide catabolic process(GO:0043171) |
| 0.1 | 0.5 | GO:1904491 | protein localization to ciliary transition zone(GO:1904491) |
| 0.1 | 1.7 | GO:0007097 | nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023) |
| 0.1 | 2.1 | GO:0045956 | positive regulation of calcium ion-dependent exocytosis(GO:0045956) |
| 0.1 | 0.7 | GO:0071569 | protein ufmylation(GO:0071569) |
| 0.1 | 0.3 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
| 0.1 | 0.8 | GO:0060019 | radial glial cell differentiation(GO:0060019) |
| 0.1 | 1.5 | GO:1900449 | regulation of glutamate receptor signaling pathway(GO:1900449) |
| 0.1 | 0.7 | GO:1900017 | positive regulation of cytokine production involved in inflammatory response(GO:1900017) |
| 0.1 | 0.2 | GO:0042663 | regulation of endodermal cell fate specification(GO:0042663) |
| 0.1 | 1.7 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
| 0.1 | 0.6 | GO:0099563 | modification of synaptic structure(GO:0099563) |
| 0.1 | 0.5 | GO:0070574 | cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574) |
| 0.1 | 1.0 | GO:0050901 | leukocyte tethering or rolling(GO:0050901) |
| 0.1 | 0.4 | GO:0042045 | epithelial fluid transport(GO:0042045) |
| 0.1 | 0.6 | GO:2001197 | regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197) |
| 0.1 | 0.5 | GO:0060770 | negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) |
| 0.1 | 0.8 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
| 0.1 | 0.4 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
| 0.1 | 0.2 | GO:0045014 | carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) |
| 0.1 | 1.0 | GO:0006353 | DNA-templated transcription, termination(GO:0006353) |
| 0.0 | 0.1 | GO:0090647 | cargo loading into vesicle(GO:0035459) modulation of age-related behavioral decline(GO:0090647) |
| 0.0 | 0.7 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
| 0.0 | 0.3 | GO:1990573 | potassium ion import across plasma membrane(GO:1990573) |
| 0.0 | 0.3 | GO:0045200 | establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) |
| 0.0 | 1.7 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.0 | 1.1 | GO:0033006 | regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304) |
| 0.0 | 1.0 | GO:0051764 | actin crosslink formation(GO:0051764) |
| 0.0 | 0.4 | GO:2000580 | positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582) |
| 0.0 | 0.4 | GO:0035562 | negative regulation of chromatin binding(GO:0035562) |
| 0.0 | 0.5 | GO:0006098 | pentose-phosphate shunt(GO:0006098) |
| 0.0 | 2.6 | GO:0080171 | lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171) |
| 0.0 | 1.9 | GO:0072527 | pyrimidine-containing compound metabolic process(GO:0072527) |
| 0.0 | 0.5 | GO:0060394 | negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394) |
| 0.0 | 2.9 | GO:0030032 | lamellipodium assembly(GO:0030032) |
| 0.0 | 0.6 | GO:0035721 | intraciliary retrograde transport(GO:0035721) |
| 0.0 | 2.2 | GO:0060999 | positive regulation of dendritic spine development(GO:0060999) |
| 0.0 | 1.8 | GO:0046825 | regulation of protein export from nucleus(GO:0046825) |
| 0.0 | 0.5 | GO:0071378 | growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378) |
| 0.0 | 0.2 | GO:0042633 | molting cycle(GO:0042303) hair cycle(GO:0042633) |
| 0.0 | 0.2 | GO:0060012 | synaptic transmission, glycinergic(GO:0060012) |
| 0.0 | 0.3 | GO:0035330 | Schwann cell proliferation(GO:0014010) regulation of hippo signaling(GO:0035330) |
| 0.0 | 0.3 | GO:1990403 | embryonic brain development(GO:1990403) |
| 0.0 | 0.2 | GO:0007035 | vacuolar acidification(GO:0007035) |
| 0.0 | 0.2 | GO:0035234 | ectopic germ cell programmed cell death(GO:0035234) |
| 0.0 | 0.8 | GO:0031297 | replication fork processing(GO:0031297) |
| 0.0 | 0.6 | GO:0045648 | positive regulation of erythrocyte differentiation(GO:0045648) |
| 0.0 | 0.2 | GO:0046415 | urate metabolic process(GO:0046415) |
| 0.0 | 1.7 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.0 | 0.4 | GO:0046688 | response to copper ion(GO:0046688) |
| 0.0 | 1.0 | GO:2000272 | negative regulation of receptor activity(GO:2000272) |
| 0.0 | 1.1 | GO:0034605 | cellular response to heat(GO:0034605) |
| 0.0 | 1.2 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
| 0.0 | 2.0 | GO:0007601 | visual perception(GO:0007601) |
| 0.0 | 0.5 | GO:0060044 | negative regulation of cardiac muscle cell proliferation(GO:0060044) |
| 0.0 | 0.2 | GO:0007016 | cytoskeletal anchoring at plasma membrane(GO:0007016) |
| 0.0 | 0.4 | GO:1904294 | positive regulation of ERAD pathway(GO:1904294) |
| 0.0 | 0.7 | GO:0007026 | negative regulation of microtubule depolymerization(GO:0007026) |
| 0.0 | 0.3 | GO:0097435 | fibril organization(GO:0097435) |
| 0.0 | 0.6 | GO:0032418 | lysosome localization(GO:0032418) |
| 0.0 | 0.1 | GO:2000258 | negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258) |
| 0.0 | 0.9 | GO:0006360 | transcription from RNA polymerase I promoter(GO:0006360) |
| 0.0 | 0.1 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
| 0.0 | 1.0 | GO:0001541 | ovarian follicle development(GO:0001541) |
| 0.0 | 0.1 | GO:1900118 | negative regulation of execution phase of apoptosis(GO:1900118) |
| 0.0 | 0.6 | GO:0042149 | cellular response to glucose starvation(GO:0042149) |
| 0.0 | 0.6 | GO:0018107 | peptidyl-threonine phosphorylation(GO:0018107) |
| 0.0 | 0.6 | GO:0051930 | regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931) |
| 0.0 | 0.2 | GO:2000051 | negative regulation of non-canonical Wnt signaling pathway(GO:2000051) |
| 0.0 | 0.1 | GO:0032211 | negative regulation of telomere maintenance via telomerase(GO:0032211) |
| 0.0 | 0.7 | GO:0045668 | negative regulation of osteoblast differentiation(GO:0045668) |
| 0.0 | 3.6 | GO:0000209 | protein polyubiquitination(GO:0000209) |
| 0.0 | 0.5 | GO:0008299 | isoprenoid biosynthetic process(GO:0008299) |
| 0.0 | 0.2 | GO:0046785 | microtubule polymerization(GO:0046785) |
| 0.0 | 0.8 | GO:0007606 | sensory perception of chemical stimulus(GO:0007606) |
| 0.0 | 0.2 | GO:0051457 | maintenance of protein location in nucleus(GO:0051457) |
| 0.0 | 0.5 | GO:0045744 | negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744) |
| 0.0 | 0.2 | GO:0043407 | negative regulation of MAP kinase activity(GO:0043407) |
| 0.0 | 0.8 | GO:0070373 | negative regulation of ERK1 and ERK2 cascade(GO:0070373) |
| 0.0 | 2.4 | GO:0009615 | response to virus(GO:0009615) |
| 0.0 | 0.6 | GO:0006513 | protein monoubiquitination(GO:0006513) |
| 0.0 | 0.4 | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146) |
| 0.0 | 0.9 | GO:0055013 | cardiac muscle cell development(GO:0055013) |
| 0.0 | 0.9 | GO:0035383 | acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383) |
| 0.0 | 1.2 | GO:0001822 | kidney development(GO:0001822) |
| 0.0 | 0.4 | GO:0003341 | cilium movement(GO:0003341) |
| 0.0 | 0.0 | GO:0006780 | uroporphyrinogen III biosynthetic process(GO:0006780) |
| 0.0 | 1.7 | GO:0001764 | neuron migration(GO:0001764) |
| 0.0 | 0.2 | GO:1903779 | regulation of cardiac conduction(GO:1903779) |
| 0.0 | 0.1 | GO:0045747 | positive regulation of Notch signaling pathway(GO:0045747) |
| 0.0 | 0.1 | GO:0045947 | negative regulation of translational initiation(GO:0045947) |
| 0.0 | 0.2 | GO:0042220 | response to cocaine(GO:0042220) |
| 0.0 | 0.2 | GO:0048147 | negative regulation of fibroblast proliferation(GO:0048147) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.8 | 5.4 | GO:1990682 | CSF1-CSF1R complex(GO:1990682) |
| 0.6 | 1.9 | GO:0036488 | CHOP-C/EBP complex(GO:0036488) |
| 0.5 | 1.6 | GO:1903095 | microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095) |
| 0.5 | 2.3 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
| 0.4 | 1.3 | GO:1990075 | kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075) |
| 0.4 | 3.8 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 0.4 | 1.1 | GO:0044299 | C-fiber(GO:0044299) |
| 0.3 | 1.2 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
| 0.2 | 0.7 | GO:0098835 | presynaptic endosome(GO:0098830) presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) |
| 0.2 | 7.4 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.2 | 0.9 | GO:0070820 | tertiary granule(GO:0070820) |
| 0.2 | 2.3 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.2 | 3.4 | GO:0031045 | dense core granule(GO:0031045) |
| 0.2 | 3.3 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
| 0.2 | 0.9 | GO:0000120 | RNA polymerase I transcription factor complex(GO:0000120) |
| 0.2 | 2.1 | GO:0044294 | dendritic growth cone(GO:0044294) |
| 0.2 | 3.4 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
| 0.2 | 1.2 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
| 0.2 | 1.1 | GO:0070695 | FHF complex(GO:0070695) |
| 0.2 | 0.5 | GO:0005965 | protein farnesyltransferase complex(GO:0005965) |
| 0.2 | 0.5 | GO:0033596 | TSC1-TSC2 complex(GO:0033596) |
| 0.1 | 0.7 | GO:0090498 | extrinsic component of Golgi membrane(GO:0090498) |
| 0.1 | 1.7 | GO:0002178 | palmitoyltransferase complex(GO:0002178) |
| 0.1 | 1.2 | GO:0032300 | mismatch repair complex(GO:0032300) |
| 0.1 | 1.8 | GO:0034362 | low-density lipoprotein particle(GO:0034362) |
| 0.1 | 0.6 | GO:0097443 | sorting endosome(GO:0097443) |
| 0.1 | 1.0 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
| 0.1 | 0.8 | GO:0005827 | polar microtubule(GO:0005827) |
| 0.1 | 1.8 | GO:0042588 | zymogen granule(GO:0042588) |
| 0.1 | 0.6 | GO:0000322 | storage vacuole(GO:0000322) |
| 0.1 | 0.6 | GO:0030870 | Mre11 complex(GO:0030870) |
| 0.1 | 1.2 | GO:0070419 | nonhomologous end joining complex(GO:0070419) |
| 0.1 | 1.0 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 0.1 | 3.4 | GO:0031672 | A band(GO:0031672) |
| 0.1 | 2.7 | GO:0030673 | axolemma(GO:0030673) |
| 0.1 | 0.6 | GO:0031105 | septin complex(GO:0031105) |
| 0.1 | 0.6 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.1 | 9.8 | GO:0042641 | actomyosin(GO:0042641) |
| 0.1 | 1.8 | GO:0005865 | striated muscle thin filament(GO:0005865) |
| 0.1 | 0.7 | GO:0036157 | outer dynein arm(GO:0036157) |
| 0.1 | 5.5 | GO:0005811 | lipid particle(GO:0005811) |
| 0.1 | 0.9 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.1 | 2.5 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 0.1 | 0.9 | GO:0097542 | ciliary tip(GO:0097542) |
| 0.1 | 1.1 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.1 | 1.9 | GO:0000407 | pre-autophagosomal structure(GO:0000407) |
| 0.1 | 0.8 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
| 0.1 | 1.0 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.1 | 1.6 | GO:0005779 | integral component of peroxisomal membrane(GO:0005779) |
| 0.0 | 8.3 | GO:0010008 | endosome membrane(GO:0010008) |
| 0.0 | 0.6 | GO:0045180 | basal cortex(GO:0045180) |
| 0.0 | 0.2 | GO:0097427 | microtubule bundle(GO:0097427) |
| 0.0 | 0.6 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 0.0 | 1.5 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.0 | 0.4 | GO:0016471 | vacuolar proton-transporting V-type ATPase complex(GO:0016471) |
| 0.0 | 0.2 | GO:0034388 | Pwp2p-containing subcomplex of 90S preribosome(GO:0034388) |
| 0.0 | 0.5 | GO:0005675 | DNA replication factor A complex(GO:0005662) holo TFIIH complex(GO:0005675) |
| 0.0 | 0.1 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
| 0.0 | 0.5 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.0 | 1.3 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.0 | 0.5 | GO:0036038 | MKS complex(GO:0036038) |
| 0.0 | 0.4 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.0 | 0.8 | GO:0060170 | ciliary membrane(GO:0060170) |
| 0.0 | 0.4 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.0 | 0.9 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.0 | 0.5 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.0 | 0.4 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.0 | 1.8 | GO:0030136 | clathrin-coated vesicle(GO:0030136) |
| 0.0 | 26.0 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
| 0.0 | 0.2 | GO:0042599 | lamellar body(GO:0042599) |
| 0.0 | 4.5 | GO:0070382 | exocytic vesicle(GO:0070382) |
| 0.0 | 0.7 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.0 | 0.2 | GO:0005916 | fascia adherens(GO:0005916) |
| 0.0 | 0.2 | GO:0070847 | core mediator complex(GO:0070847) |
| 0.0 | 1.0 | GO:0016235 | aggresome(GO:0016235) |
| 0.0 | 0.0 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 0.0 | 0.5 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.0 | 1.9 | GO:0045111 | intermediate filament cytoskeleton(GO:0045111) |
| 0.0 | 2.2 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 1.1 | GO:0005770 | late endosome(GO:0005770) |
| 0.0 | 0.7 | GO:0005902 | microvillus(GO:0005902) |
| 0.0 | 1.0 | GO:0042383 | sarcolemma(GO:0042383) |
| 0.0 | 5.0 | GO:0005764 | lytic vacuole(GO:0000323) lysosome(GO:0005764) |
| 0.0 | 0.7 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 2.0 | GO:0045211 | postsynaptic membrane(GO:0045211) |
| 0.0 | 0.3 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.0 | 0.2 | GO:0014704 | intercalated disc(GO:0014704) |
| 0.0 | 1.1 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 0.0 | 0.1 | GO:0000783 | telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) |
| 0.0 | 0.7 | GO:0055037 | recycling endosome(GO:0055037) |
| 0.0 | 0.2 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.0 | 0.8 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 2.8 | GO:0005768 | endosome(GO:0005768) |
| 0.0 | 0.2 | GO:0030914 | STAGA complex(GO:0030914) |
| 0.0 | 0.3 | GO:0008180 | COP9 signalosome(GO:0008180) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 4.7 | GO:0001716 | L-amino-acid oxidase activity(GO:0001716) |
| 1.2 | 4.8 | GO:0004966 | galanin receptor activity(GO:0004966) |
| 0.9 | 4.5 | GO:0019770 | IgG receptor activity(GO:0019770) |
| 0.8 | 2.5 | GO:0003986 | acetyl-CoA hydrolase activity(GO:0003986) |
| 0.8 | 2.3 | GO:0003796 | lysozyme activity(GO:0003796) |
| 0.7 | 5.0 | GO:0004303 | estradiol 17-beta-dehydrogenase activity(GO:0004303) |
| 0.7 | 2.6 | GO:0017050 | sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050) |
| 0.6 | 1.8 | GO:0016262 | protein N-acetylglucosaminyltransferase activity(GO:0016262) |
| 0.6 | 1.7 | GO:0004510 | tryptophan 5-monooxygenase activity(GO:0004510) |
| 0.6 | 8.3 | GO:0005537 | mannose binding(GO:0005537) |
| 0.5 | 2.7 | GO:0003835 | beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835) |
| 0.5 | 1.4 | GO:0019120 | hydrolase activity, acting on acid halide bonds(GO:0016824) hydrolase activity, acting on acid halide bonds, in C-halide compounds(GO:0019120) alkylhalidase activity(GO:0047651) |
| 0.5 | 1.4 | GO:0004998 | transferrin receptor activity(GO:0004998) |
| 0.5 | 1.8 | GO:0001537 | N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537) |
| 0.5 | 1.8 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
| 0.4 | 1.3 | GO:0036313 | phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313) |
| 0.4 | 5.7 | GO:0031005 | filamin binding(GO:0031005) |
| 0.4 | 1.2 | GO:0032139 | dinucleotide insertion or deletion binding(GO:0032139) single guanine insertion binding(GO:0032142) |
| 0.3 | 1.6 | GO:0080019 | fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019) |
| 0.3 | 1.0 | GO:0004534 | transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160) 5'-3' exoribonuclease activity(GO:0004534) |
| 0.3 | 1.6 | GO:0004525 | ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) |
| 0.3 | 2.7 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.3 | 1.5 | GO:0015091 | ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510) |
| 0.3 | 8.3 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.3 | 1.1 | GO:0070740 | tubulin-glutamic acid ligase activity(GO:0070740) |
| 0.3 | 6.6 | GO:0042287 | MHC protein binding(GO:0042287) |
| 0.3 | 1.1 | GO:0004515 | nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515) |
| 0.3 | 1.1 | GO:0000832 | inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724) |
| 0.2 | 2.0 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.2 | 0.8 | GO:0070573 | metallodipeptidase activity(GO:0070573) |
| 0.2 | 1.8 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.2 | 1.0 | GO:0004359 | glutaminase activity(GO:0004359) |
| 0.2 | 0.8 | GO:0004345 | glucose-6-phosphate dehydrogenase activity(GO:0004345) |
| 0.2 | 0.6 | GO:0042954 | lipoprotein transporter activity(GO:0042954) |
| 0.2 | 1.5 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.2 | 0.7 | GO:0016812 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812) |
| 0.2 | 1.8 | GO:0047499 | calcium-independent phospholipase A2 activity(GO:0047499) |
| 0.2 | 3.7 | GO:0005521 | lamin binding(GO:0005521) |
| 0.2 | 0.5 | GO:0004660 | protein farnesyltransferase activity(GO:0004660) |
| 0.2 | 3.4 | GO:0042056 | chemoattractant activity(GO:0042056) |
| 0.1 | 0.6 | GO:0051880 | G-quadruplex DNA binding(GO:0051880) |
| 0.1 | 1.0 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 0.1 | 0.8 | GO:0016300 | tRNA (uracil) methyltransferase activity(GO:0016300) |
| 0.1 | 2.7 | GO:0001848 | complement binding(GO:0001848) |
| 0.1 | 1.2 | GO:0035312 | 5'-3' exodeoxyribonuclease activity(GO:0035312) |
| 0.1 | 0.9 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
| 0.1 | 2.3 | GO:0070566 | adenylyltransferase activity(GO:0070566) |
| 0.1 | 1.9 | GO:0001013 | RNA polymerase I regulatory region DNA binding(GO:0001013) |
| 0.1 | 5.1 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.1 | 0.6 | GO:0048248 | CXCR3 chemokine receptor binding(GO:0048248) |
| 0.1 | 0.6 | GO:0038085 | vascular endothelial growth factor binding(GO:0038085) |
| 0.1 | 0.5 | GO:0050347 | trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347) |
| 0.1 | 2.5 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.1 | 0.5 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
| 0.1 | 0.5 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
| 0.1 | 0.5 | GO:0000405 | bubble DNA binding(GO:0000405) |
| 0.1 | 2.9 | GO:0043236 | laminin binding(GO:0043236) |
| 0.1 | 1.8 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.1 | 1.0 | GO:0008517 | folic acid transporter activity(GO:0008517) |
| 0.1 | 1.6 | GO:0070300 | phosphatidic acid binding(GO:0070300) |
| 0.1 | 3.0 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.1 | 1.2 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.1 | 1.2 | GO:0043008 | ATP-dependent protein binding(GO:0043008) |
| 0.1 | 1.5 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.1 | 0.3 | GO:0015410 | manganese-transporting ATPase activity(GO:0015410) |
| 0.1 | 0.9 | GO:0005384 | manganese ion transmembrane transporter activity(GO:0005384) |
| 0.1 | 0.4 | GO:0016778 | diphosphotransferase activity(GO:0016778) |
| 0.1 | 0.3 | GO:0031727 | CCR2 chemokine receptor binding(GO:0031727) |
| 0.1 | 1.6 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 0.1 | 0.4 | GO:0030144 | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144) |
| 0.1 | 1.1 | GO:0015149 | glucose transmembrane transporter activity(GO:0005355) hexose transmembrane transporter activity(GO:0015149) |
| 0.1 | 0.8 | GO:0035615 | clathrin heavy chain binding(GO:0032050) clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.1 | 0.4 | GO:0008294 | calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294) |
| 0.1 | 1.0 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.1 | 0.6 | GO:0051022 | Rho GDP-dissociation inhibitor binding(GO:0051022) |
| 0.1 | 0.2 | GO:0016934 | extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934) |
| 0.1 | 1.8 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
| 0.1 | 0.3 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.1 | 1.7 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.1 | 2.8 | GO:0070888 | E-box binding(GO:0070888) |
| 0.1 | 0.2 | GO:0004784 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
| 0.1 | 1.0 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
| 0.1 | 3.0 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.1 | 0.4 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.1 | 0.3 | GO:0016401 | palmitoyl-CoA oxidase activity(GO:0016401) |
| 0.1 | 2.7 | GO:0051019 | mitogen-activated protein kinase binding(GO:0051019) |
| 0.0 | 3.1 | GO:0004714 | transmembrane receptor protein tyrosine kinase activity(GO:0004714) |
| 0.0 | 0.3 | GO:0003831 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831) |
| 0.0 | 0.3 | GO:0016004 | phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229) |
| 0.0 | 0.7 | GO:0070403 | NAD+ binding(GO:0070403) |
| 0.0 | 0.1 | GO:0019863 | IgE binding(GO:0019863) |
| 0.0 | 2.1 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.0 | 0.2 | GO:0001010 | transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) |
| 0.0 | 2.6 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.0 | 0.4 | GO:0070569 | uridylyltransferase activity(GO:0070569) |
| 0.0 | 0.6 | GO:0070742 | C2H2 zinc finger domain binding(GO:0070742) |
| 0.0 | 1.0 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.0 | 3.5 | GO:0005125 | cytokine activity(GO:0005125) |
| 0.0 | 0.4 | GO:0050815 | phosphoserine binding(GO:0050815) |
| 0.0 | 0.4 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
| 0.0 | 0.2 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 0.0 | 1.7 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 0.0 | 3.1 | GO:0005178 | integrin binding(GO:0005178) |
| 0.0 | 1.3 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.0 | 0.5 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
| 0.0 | 0.9 | GO:0008200 | ion channel inhibitor activity(GO:0008200) |
| 0.0 | 3.6 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.0 | 1.4 | GO:0051018 | protein kinase A binding(GO:0051018) |
| 0.0 | 0.3 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.0 | 0.7 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 1.3 | GO:0030276 | clathrin binding(GO:0030276) |
| 0.0 | 2.6 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 1.6 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
| 0.0 | 0.2 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.0 | 0.3 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.0 | 0.5 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.0 | 0.2 | GO:0097153 | cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153) cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200) |
| 0.0 | 0.3 | GO:0050998 | nitric-oxide synthase binding(GO:0050998) |
| 0.0 | 2.6 | GO:0005539 | glycosaminoglycan binding(GO:0005539) |
| 0.0 | 3.9 | GO:0001047 | core promoter binding(GO:0001047) |
| 0.0 | 0.3 | GO:0032452 | histone demethylase activity(GO:0032452) |
| 0.0 | 1.2 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
| 0.0 | 0.5 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.0 | 0.3 | GO:0070411 | I-SMAD binding(GO:0070411) |
| 0.0 | 1.3 | GO:0042626 | ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492) |
| 0.0 | 0.4 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
| 0.0 | 0.7 | GO:0031369 | translation initiation factor binding(GO:0031369) |
| 0.0 | 0.8 | GO:0030170 | pyridoxal phosphate binding(GO:0030170) |
| 0.0 | 0.7 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 0.0 | 2.1 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.0 | 0.0 | GO:0004706 | JUN kinase kinase kinase activity(GO:0004706) |
| 0.0 | 0.8 | GO:0030295 | protein kinase activator activity(GO:0030295) |
| 0.0 | 0.3 | GO:0005326 | neurotransmitter transporter activity(GO:0005326) |
| 0.0 | 0.1 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
| 0.0 | 0.1 | GO:0004066 | asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066) |
| 0.0 | 0.1 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.0 | 2.9 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
| 0.0 | 0.8 | GO:0005249 | voltage-gated potassium channel activity(GO:0005249) |
| 0.0 | 0.2 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.5 | PID_ERBB_NETWORK_PATHWAY | ErbB receptor signaling network |
| 0.1 | 2.6 | PID_S1P_META_PATHWAY | Sphingosine 1-phosphate (S1P) pathway |
| 0.1 | 2.0 | PID_SYNDECAN_3_PATHWAY | Syndecan-3-mediated signaling events |
| 0.1 | 1.7 | PID_CIRCADIAN_PATHWAY | Circadian rhythm pathway |
| 0.1 | 5.6 | PID_TCPTP_PATHWAY | Signaling events mediated by TCPTP |
| 0.1 | 1.9 | ST_G_ALPHA_S_PATHWAY | G alpha s Pathway |
| 0.1 | 0.6 | PID_S1P_S1P4_PATHWAY | S1P4 pathway |
| 0.1 | 3.0 | PID_FRA_PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.1 | 3.6 | PID_AJDISS_2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.1 | 1.7 | PID_ARF6_PATHWAY | Arf6 signaling events |
| 0.1 | 2.3 | PID_ATM_PATHWAY | ATM pathway |
| 0.1 | 1.8 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 3.2 | PID_MYC_REPRESS_PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 1.1 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
| 0.0 | 0.9 | PID_CXCR3_PATHWAY | CXCR3-mediated signaling events |
| 0.0 | 0.6 | PID_ERBB2_ERBB3_PATHWAY | ErbB2/ErbB3 signaling events |
| 0.0 | 1.0 | ST_ADRENERGIC | Adrenergic Pathway |
| 0.0 | 1.3 | PID_ERBB1_INTERNALIZATION_PATHWAY | Internalization of ErbB1 |
| 0.0 | 0.4 | PID_LPA4_PATHWAY | LPA4-mediated signaling events |
| 0.0 | 0.5 | PID_GLYPICAN_1PATHWAY | Glypican 1 network |
| 0.0 | 0.9 | PID_CD8_TCR_PATHWAY | TCR signaling in naïve CD8+ T cells |
| 0.0 | 1.7 | PID_CDC42_PATHWAY | CDC42 signaling events |
| 0.0 | 0.5 | PID_IL2_1PATHWAY | IL2-mediated signaling events |
| 0.0 | 2.9 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 0.2 | PID_IL2_PI3K_PATHWAY | IL2 signaling events mediated by PI3K |
| 0.0 | 0.7 | PID_ILK_PATHWAY | Integrin-linked kinase signaling |
| 0.0 | 0.7 | PID_P53_DOWNSTREAM_PATHWAY | Direct p53 effectors |
| 0.0 | 0.8 | SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
| 0.0 | 2.1 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 0.5 | PID_ATF2_PATHWAY | ATF-2 transcription factor network |
| 0.0 | 0.4 | PID_ARF_3PATHWAY | Arf1 pathway |
| 0.0 | 0.7 | PID_RB_1PATHWAY | Regulation of retinoblastoma protein |
| 0.0 | 0.2 | PID_MYC_PATHWAY | C-MYC pathway |
| 0.0 | 0.2 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 3.8 | REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
| 0.3 | 2.0 | REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
| 0.2 | 5.0 | REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.2 | 4.3 | REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.2 | 2.7 | REACTOME_ACTIVATION_OF_RAC | Genes involved in Activation of Rac |
| 0.2 | 1.5 | REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.2 | 3.1 | REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.2 | 1.7 | REACTOME_AMINE_DERIVED_HORMONES | Genes involved in Amine-derived hormones |
| 0.1 | 1.1 | REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.1 | 2.3 | REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.1 | 3.4 | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.1 | 4.0 | REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.1 | 1.6 | REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.1 | 1.3 | REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.1 | 4.5 | REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES | Genes involved in Cross-presentation of soluble exogenous antigens (endosomes) |
| 0.1 | 1.2 | REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 0.1 | 2.0 | REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
| 0.1 | 1.7 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.1 | 0.2 | REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT | Genes involved in Ligand-gated ion channel transport |
| 0.1 | 2.5 | REACTOME_INTERFERON_ALPHA_BETA_SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.1 | 1.4 | REACTOME_STRIATED_MUSCLE_CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.1 | 0.9 | REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D | Genes involved in Metabolism of steroid hormones and vitamins A and D |
| 0.0 | 1.7 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.0 | 0.6 | REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.0 | 0.6 | REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
| 0.0 | 1.3 | REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
| 0.0 | 1.0 | REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 0.0 | 0.7 | REACTOME_CRMPS_IN_SEMA3A_SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.0 | 1.3 | REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.0 | 0.8 | REACTOME_MICRORNA_MIRNA_BIOGENESIS | Genes involved in MicroRNA (miRNA) Biogenesis |
| 0.0 | 0.5 | REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER | Genes involved in Formation of incision complex in GG-NER |
| 0.0 | 0.6 | REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
| 0.0 | 0.6 | REACTOME_METABOLISM_OF_POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.0 | 0.2 | REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
| 0.0 | 1.7 | REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.0 | 2.0 | REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.0 | 0.9 | REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION | Genes involved in RNA Polymerase I Transcription Termination |
| 0.0 | 0.4 | REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY | Genes involved in Adenylate cyclase activating pathway |
| 0.0 | 0.5 | REACTOME_RAF_MAP_KINASE_CASCADE | Genes involved in RAF/MAP kinase cascade |
| 0.0 | 0.4 | REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.0 | 0.5 | REACTOME_ZINC_TRANSPORTERS | Genes involved in Zinc transporters |
| 0.0 | 1.2 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.0 | 0.4 | REACTOME_COPI_MEDIATED_TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.0 | 1.0 | REACTOME_NOD1_2_SIGNALING_PATHWAY | Genes involved in NOD1/2 Signaling Pathway |
| 0.0 | 0.7 | REACTOME_GLUTATHIONE_CONJUGATION | Genes involved in Glutathione conjugation |
| 0.0 | 1.6 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.0 | 0.1 | REACTOME_ENDOGENOUS_STEROLS | Genes involved in Endogenous sterols |
| 0.0 | 0.7 | REACTOME_PEROXISOMAL_LIPID_METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.0 | 0.8 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.0 | 0.6 | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.0 | 0.3 | REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS | Genes involved in CREB phosphorylation through the activation of Ras |
| 0.0 | 2.5 | REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES | Genes involved in Transmission across Chemical Synapses |
| 0.0 | 0.2 | REACTOME_MEIOTIC_RECOMBINATION | Genes involved in Meiotic Recombination |
| 0.0 | 0.4 | REACTOME_SYNTHESIS_OF_PA | Genes involved in Synthesis of PA |
| 0.0 | 0.2 | REACTOME_RNA_POL_III_CHAIN_ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
| 0.0 | 0.3 | REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
