Motif ID: E2f6
Z-value: 0.979
Transcription factors associated with E2f6:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| E2f6 | ENSMUSG00000057469.7 | E2f6 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| E2f6 | mm10_v2_chr12_+_16810940_16810978 | 0.67 | 2.2e-08 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 7.4 | 22.2 | GO:0061075 | cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871) |
| 4.5 | 13.4 | GO:0030421 | defecation(GO:0030421) |
| 2.8 | 34.0 | GO:0060272 | embryonic skeletal joint morphogenesis(GO:0060272) |
| 2.8 | 5.5 | GO:0072180 | mesonephric duct development(GO:0072177) mesonephric duct morphogenesis(GO:0072180) |
| 2.7 | 2.7 | GO:0072197 | ureter morphogenesis(GO:0072197) |
| 2.4 | 9.6 | GO:0060741 | prostate gland stromal morphogenesis(GO:0060741) |
| 2.0 | 4.1 | GO:0061144 | alveolar secondary septum development(GO:0061144) |
| 2.0 | 8.0 | GO:0003360 | brainstem development(GO:0003360) |
| 1.9 | 5.7 | GO:0003221 | right ventricular cardiac muscle tissue morphogenesis(GO:0003221) |
| 1.9 | 13.3 | GO:0030916 | otic vesicle formation(GO:0030916) |
| 1.9 | 7.5 | GO:2000525 | regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) |
| 1.5 | 4.5 | GO:1901079 | positive regulation of relaxation of muscle(GO:1901079) |
| 1.4 | 2.7 | GO:0023016 | signal transduction by trans-phosphorylation(GO:0023016) |
| 1.3 | 5.1 | GO:0015888 | thiamine transport(GO:0015888) |
| 1.2 | 3.6 | GO:0045004 | DNA replication proofreading(GO:0045004) |
| 1.2 | 3.6 | GO:0060364 | frontal suture morphogenesis(GO:0060364) |
| 1.2 | 25.8 | GO:0060009 | Sertoli cell development(GO:0060009) |
| 1.2 | 3.5 | GO:0006566 | threonine metabolic process(GO:0006566) |
| 1.1 | 9.0 | GO:0044027 | hypermethylation of CpG island(GO:0044027) |
| 1.1 | 3.3 | GO:0060244 | negative regulation of cell proliferation involved in contact inhibition(GO:0060244) |
| 1.1 | 3.3 | GO:0021759 | globus pallidus development(GO:0021759) |
| 1.1 | 3.3 | GO:0006226 | dUMP biosynthetic process(GO:0006226) |
| 1.0 | 2.1 | GO:0045658 | regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659) |
| 1.0 | 4.1 | GO:0072103 | glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104) |
| 1.0 | 4.0 | GO:0072049 | comma-shaped body morphogenesis(GO:0072049) |
| 1.0 | 1.0 | GO:0060769 | positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769) |
| 0.9 | 4.7 | GO:0007223 | Wnt signaling pathway, calcium modulating pathway(GO:0007223) |
| 0.9 | 3.7 | GO:0014722 | regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722) |
| 0.9 | 2.7 | GO:0070172 | positive regulation of tooth mineralization(GO:0070172) |
| 0.9 | 6.2 | GO:0033567 | DNA replication, Okazaki fragment processing(GO:0033567) |
| 0.9 | 3.6 | GO:0010288 | response to lead ion(GO:0010288) |
| 0.9 | 2.6 | GO:1901420 | negative regulation of response to alcohol(GO:1901420) |
| 0.9 | 13.2 | GO:0009263 | deoxyribonucleotide biosynthetic process(GO:0009263) |
| 0.9 | 2.6 | GO:0002302 | CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) mesodermal to mesenchymal transition involved in gastrulation(GO:0060809) |
| 0.9 | 2.6 | GO:0032877 | positive regulation of DNA endoreduplication(GO:0032877) |
| 0.9 | 6.1 | GO:0051660 | establishment of centrosome localization(GO:0051660) |
| 0.8 | 2.5 | GO:0002191 | cap-dependent translational initiation(GO:0002191) |
| 0.8 | 2.5 | GO:0007228 | positive regulation of hh target transcription factor activity(GO:0007228) |
| 0.8 | 2.5 | GO:1904020 | regulation of G-protein coupled receptor internalization(GO:1904020) |
| 0.8 | 2.4 | GO:1904975 | response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976) |
| 0.8 | 2.4 | GO:0030200 | heparan sulfate proteoglycan catabolic process(GO:0030200) |
| 0.8 | 3.2 | GO:0021797 | forebrain anterior/posterior pattern specification(GO:0021797) |
| 0.8 | 2.4 | GO:0007161 | calcium-independent cell-matrix adhesion(GO:0007161) |
| 0.8 | 2.3 | GO:0036388 | pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) DNA replication preinitiation complex assembly(GO:0071163) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299) |
| 0.8 | 2.3 | GO:1902162 | regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) |
| 0.8 | 3.8 | GO:1904936 | cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936) |
| 0.7 | 3.0 | GO:0033085 | negative regulation of T cell differentiation in thymus(GO:0033085) negative regulation of interleukin-6 biosynthetic process(GO:0045409) |
| 0.7 | 0.7 | GO:0007352 | zygotic specification of dorsal/ventral axis(GO:0007352) |
| 0.7 | 3.6 | GO:1900170 | negative regulation of glucocorticoid mediated signaling pathway(GO:1900170) |
| 0.7 | 2.1 | GO:0021529 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) |
| 0.7 | 2.1 | GO:0036292 | DNA rewinding(GO:0036292) |
| 0.7 | 2.1 | GO:0072554 | blood vessel lumenization(GO:0072554) |
| 0.7 | 3.5 | GO:1903553 | positive regulation of extracellular exosome assembly(GO:1903553) |
| 0.7 | 2.1 | GO:2000297 | negative regulation of synapse maturation(GO:2000297) |
| 0.7 | 2.1 | GO:0071918 | urea transmembrane transport(GO:0071918) |
| 0.7 | 1.4 | GO:0061314 | Notch signaling involved in heart development(GO:0061314) |
| 0.7 | 6.9 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
| 0.7 | 3.4 | GO:0006189 | 'de novo' IMP biosynthetic process(GO:0006189) |
| 0.7 | 1.3 | GO:1900220 | semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220) |
| 0.6 | 3.2 | GO:1903609 | negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609) |
| 0.6 | 1.9 | GO:0030202 | heparin metabolic process(GO:0030202) |
| 0.6 | 1.9 | GO:0007084 | mitotic nuclear envelope reassembly(GO:0007084) |
| 0.6 | 2.5 | GO:1900224 | positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224) |
| 0.6 | 4.3 | GO:0006348 | chromatin silencing at telomere(GO:0006348) |
| 0.6 | 6.7 | GO:0010216 | maintenance of DNA methylation(GO:0010216) |
| 0.6 | 19.4 | GO:0006270 | DNA replication initiation(GO:0006270) |
| 0.6 | 1.8 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
| 0.6 | 2.4 | GO:0006269 | DNA replication, synthesis of RNA primer(GO:0006269) |
| 0.6 | 3.6 | GO:0006344 | maintenance of chromatin silencing(GO:0006344) |
| 0.6 | 3.3 | GO:1902965 | regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966) |
| 0.5 | 2.7 | GO:0007089 | traversing start control point of mitotic cell cycle(GO:0007089) |
| 0.5 | 2.1 | GO:0035606 | peptidyl-cysteine S-trans-nitrosylation(GO:0035606) |
| 0.5 | 6.8 | GO:0014842 | regulation of skeletal muscle satellite cell proliferation(GO:0014842) regulation of skeletal muscle cell proliferation(GO:0014857) |
| 0.5 | 5.2 | GO:0021521 | ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573) |
| 0.5 | 1.5 | GO:0086053 | AV node cell to bundle of His cell communication by electrical coupling(GO:0086053) |
| 0.5 | 2.0 | GO:2001045 | response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681) negative regulation of integrin-mediated signaling pathway(GO:2001045) |
| 0.5 | 1.9 | GO:0070829 | heterochromatin maintenance(GO:0070829) |
| 0.5 | 0.9 | GO:0009957 | epidermal cell fate specification(GO:0009957) |
| 0.4 | 3.6 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 0.4 | 1.3 | GO:0014834 | skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834) |
| 0.4 | 0.9 | GO:2000138 | positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138) |
| 0.4 | 4.4 | GO:0090527 | actin filament reorganization(GO:0090527) |
| 0.4 | 2.2 | GO:0060849 | regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849) |
| 0.4 | 8.2 | GO:0040034 | regulation of development, heterochronic(GO:0040034) |
| 0.4 | 0.9 | GO:0071707 | immunoglobulin heavy chain V-D-J recombination(GO:0071707) |
| 0.4 | 0.4 | GO:0060298 | positive regulation of sarcomere organization(GO:0060298) |
| 0.4 | 0.4 | GO:1901187 | regulation of ephrin receptor signaling pathway(GO:1901187) |
| 0.4 | 2.1 | GO:0045578 | negative regulation of B cell differentiation(GO:0045578) |
| 0.4 | 7.9 | GO:0045653 | negative regulation of megakaryocyte differentiation(GO:0045653) |
| 0.4 | 11.9 | GO:0043153 | entrainment of circadian clock by photoperiod(GO:0043153) |
| 0.4 | 2.4 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
| 0.4 | 0.8 | GO:1903588 | negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588) |
| 0.4 | 4.3 | GO:0048096 | chromatin-mediated maintenance of transcription(GO:0048096) |
| 0.4 | 1.2 | GO:0090271 | positive regulation of fibroblast growth factor production(GO:0090271) |
| 0.4 | 2.3 | GO:0060836 | lymphatic endothelial cell differentiation(GO:0060836) |
| 0.4 | 0.8 | GO:0001787 | natural killer cell proliferation(GO:0001787) |
| 0.4 | 0.8 | GO:0072053 | renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054) |
| 0.4 | 1.9 | GO:0060040 | retinal bipolar neuron differentiation(GO:0060040) |
| 0.4 | 1.1 | GO:0002184 | cytoplasmic translational termination(GO:0002184) |
| 0.4 | 1.1 | GO:0010957 | negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137) |
| 0.4 | 0.8 | GO:0021506 | anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995) |
| 0.4 | 1.5 | GO:0030860 | regulation of polarized epithelial cell differentiation(GO:0030860) |
| 0.4 | 1.1 | GO:0031660 | regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) |
| 0.4 | 1.8 | GO:0090273 | regulation of somatostatin secretion(GO:0090273) |
| 0.4 | 4.3 | GO:0045603 | positive regulation of endothelial cell differentiation(GO:0045603) |
| 0.4 | 4.7 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
| 0.4 | 2.5 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
| 0.4 | 3.6 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
| 0.4 | 0.7 | GO:0033128 | negative regulation of histone phosphorylation(GO:0033128) |
| 0.3 | 1.0 | GO:1901675 | negative regulation of histone H3-K27 acetylation(GO:1901675) |
| 0.3 | 1.7 | GO:0048133 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
| 0.3 | 0.7 | GO:0097360 | chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382) |
| 0.3 | 1.7 | GO:0019065 | receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509) |
| 0.3 | 0.3 | GO:0048023 | positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378) |
| 0.3 | 2.0 | GO:0044806 | G-quadruplex DNA unwinding(GO:0044806) |
| 0.3 | 2.3 | GO:1990504 | dense core granule exocytosis(GO:1990504) |
| 0.3 | 2.9 | GO:0001675 | acrosome assembly(GO:0001675) |
| 0.3 | 1.0 | GO:0003032 | detection of oxygen(GO:0003032) |
| 0.3 | 3.2 | GO:0033631 | cell-cell adhesion mediated by integrin(GO:0033631) |
| 0.3 | 1.3 | GO:0072272 | proximal/distal pattern formation involved in metanephric nephron development(GO:0072272) |
| 0.3 | 1.3 | GO:0006526 | arginine biosynthetic process(GO:0006526) |
| 0.3 | 0.6 | GO:0060216 | definitive hemopoiesis(GO:0060216) |
| 0.3 | 0.3 | GO:2000850 | negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850) |
| 0.3 | 1.2 | GO:0035624 | receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) response to high density lipoprotein particle(GO:0055099) |
| 0.3 | 5.0 | GO:0038092 | nodal signaling pathway(GO:0038092) |
| 0.3 | 2.1 | GO:2000348 | regulation of CD40 signaling pathway(GO:2000348) |
| 0.3 | 3.3 | GO:0046643 | regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643) |
| 0.3 | 1.2 | GO:0051295 | establishment of meiotic spindle localization(GO:0051295) |
| 0.3 | 0.9 | GO:0030208 | dermatan sulfate biosynthetic process(GO:0030208) |
| 0.3 | 1.2 | GO:2001185 | regulation of CD8-positive, alpha-beta T cell activation(GO:2001185) |
| 0.3 | 1.1 | GO:0000415 | negative regulation of histone H3-K36 methylation(GO:0000415) |
| 0.3 | 0.9 | GO:0000448 | cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448) rRNA export from nucleus(GO:0006407) |
| 0.3 | 1.7 | GO:0033563 | dorsal/ventral axon guidance(GO:0033563) |
| 0.3 | 0.5 | GO:0060744 | thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744) |
| 0.3 | 0.8 | GO:0010641 | positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641) |
| 0.3 | 6.7 | GO:1902043 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043) |
| 0.3 | 1.6 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
| 0.3 | 0.8 | GO:1904690 | regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690) |
| 0.3 | 2.4 | GO:0048664 | neuron fate determination(GO:0048664) |
| 0.3 | 1.3 | GO:0019852 | L-ascorbic acid metabolic process(GO:0019852) |
| 0.3 | 0.8 | GO:0019441 | tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218) kynurenine metabolic process(GO:0070189) |
| 0.3 | 1.0 | GO:0061743 | motor learning(GO:0061743) |
| 0.3 | 2.8 | GO:0032825 | positive regulation of natural killer cell differentiation(GO:0032825) |
| 0.2 | 3.5 | GO:0035563 | positive regulation of chromatin binding(GO:0035563) |
| 0.2 | 0.2 | GO:0038163 | thrombopoietin-mediated signaling pathway(GO:0038163) |
| 0.2 | 1.0 | GO:2001032 | regulation of double-strand break repair via nonhomologous end joining(GO:2001032) |
| 0.2 | 1.9 | GO:0018158 | protein oxidation(GO:0018158) |
| 0.2 | 0.5 | GO:0043570 | maintenance of DNA repeat elements(GO:0043570) |
| 0.2 | 4.7 | GO:0071392 | cellular response to estradiol stimulus(GO:0071392) |
| 0.2 | 1.1 | GO:0038018 | Wnt receptor catabolic process(GO:0038018) |
| 0.2 | 1.5 | GO:0008343 | adult feeding behavior(GO:0008343) |
| 0.2 | 1.8 | GO:0070940 | dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940) |
| 0.2 | 0.4 | GO:0032627 | interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) |
| 0.2 | 0.8 | GO:0090209 | negative regulation of triglyceride metabolic process(GO:0090209) |
| 0.2 | 2.7 | GO:0035584 | calcium-mediated signaling using intracellular calcium source(GO:0035584) |
| 0.2 | 1.5 | GO:0016127 | cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127) |
| 0.2 | 2.5 | GO:0061029 | eyelid development in camera-type eye(GO:0061029) |
| 0.2 | 3.7 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.2 | 1.6 | GO:1900262 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
| 0.2 | 1.0 | GO:0001561 | fatty acid alpha-oxidation(GO:0001561) |
| 0.2 | 0.2 | GO:0097296 | activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296) |
| 0.2 | 0.8 | GO:0009414 | response to water deprivation(GO:0009414) |
| 0.2 | 2.0 | GO:0060059 | embryonic retina morphogenesis in camera-type eye(GO:0060059) |
| 0.2 | 1.8 | GO:0031547 | brain-derived neurotrophic factor receptor signaling pathway(GO:0031547) |
| 0.2 | 1.4 | GO:0000056 | ribosomal small subunit export from nucleus(GO:0000056) |
| 0.2 | 9.1 | GO:2000134 | negative regulation of G1/S transition of mitotic cell cycle(GO:2000134) |
| 0.2 | 1.0 | GO:0090336 | positive regulation of brown fat cell differentiation(GO:0090336) |
| 0.2 | 1.0 | GO:0039703 | viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) |
| 0.2 | 0.8 | GO:0001887 | selenium compound metabolic process(GO:0001887) selenocysteine metabolic process(GO:0016259) |
| 0.2 | 0.6 | GO:0001827 | inner cell mass cell fate commitment(GO:0001827) |
| 0.2 | 0.8 | GO:2001245 | regulation of phosphatidylcholine biosynthetic process(GO:2001245) |
| 0.2 | 1.9 | GO:0021542 | dentate gyrus development(GO:0021542) |
| 0.2 | 1.7 | GO:0061299 | retina vasculature morphogenesis in camera-type eye(GO:0061299) |
| 0.2 | 1.5 | GO:0006362 | transcription elongation from RNA polymerase I promoter(GO:0006362) |
| 0.2 | 1.3 | GO:0043921 | modulation by host of viral transcription(GO:0043921) modulation of transcription in other organism involved in symbiotic interaction(GO:0052312) modulation by host of symbiont transcription(GO:0052472) |
| 0.2 | 0.4 | GO:0030997 | regulation of centriole-centriole cohesion(GO:0030997) |
| 0.2 | 1.8 | GO:0060430 | lung saccule development(GO:0060430) |
| 0.2 | 1.5 | GO:0070423 | nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431) |
| 0.2 | 0.7 | GO:1903546 | protein localization to photoreceptor outer segment(GO:1903546) |
| 0.2 | 2.0 | GO:0031936 | negative regulation of chromatin silencing(GO:0031936) |
| 0.2 | 1.8 | GO:0051602 | response to electrical stimulus(GO:0051602) |
| 0.2 | 1.1 | GO:0060736 | prostate gland growth(GO:0060736) |
| 0.2 | 0.7 | GO:1900186 | negative regulation of clathrin-mediated endocytosis(GO:1900186) |
| 0.2 | 1.8 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
| 0.2 | 0.4 | GO:0018214 | peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214) |
| 0.2 | 0.5 | GO:0002946 | tRNA C5-cytosine methylation(GO:0002946) |
| 0.2 | 5.4 | GO:0046677 | response to antibiotic(GO:0046677) |
| 0.2 | 2.4 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) |
| 0.2 | 2.7 | GO:0050774 | negative regulation of dendrite morphogenesis(GO:0050774) |
| 0.2 | 2.5 | GO:0098743 | cartilage condensation(GO:0001502) cell aggregation(GO:0098743) |
| 0.2 | 2.0 | GO:0051292 | nuclear pore complex assembly(GO:0051292) |
| 0.2 | 3.4 | GO:0050434 | positive regulation of viral transcription(GO:0050434) |
| 0.2 | 0.5 | GO:0010533 | regulation of activation of Janus kinase activity(GO:0010533) |
| 0.2 | 0.3 | GO:0010920 | negative regulation of inositol phosphate biosynthetic process(GO:0010920) |
| 0.2 | 1.1 | GO:0019336 | phenol-containing compound catabolic process(GO:0019336) |
| 0.2 | 0.6 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 0.2 | 2.5 | GO:0034377 | plasma lipoprotein particle assembly(GO:0034377) |
| 0.2 | 0.6 | GO:0060709 | glycogen cell differentiation involved in embryonic placenta development(GO:0060709) |
| 0.2 | 0.8 | GO:2000623 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
| 0.2 | 1.1 | GO:0097237 | cellular response to toxic substance(GO:0097237) |
| 0.2 | 1.4 | GO:0035988 | chondrocyte proliferation(GO:0035988) |
| 0.2 | 1.1 | GO:0033601 | positive regulation of mammary gland epithelial cell proliferation(GO:0033601) |
| 0.2 | 0.6 | GO:0015744 | succinate transport(GO:0015744) |
| 0.2 | 0.5 | GO:0015772 | disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772) |
| 0.1 | 1.5 | GO:0090136 | epithelial cell-cell adhesion(GO:0090136) |
| 0.1 | 2.5 | GO:0043567 | regulation of insulin-like growth factor receptor signaling pathway(GO:0043567) |
| 0.1 | 0.4 | GO:0007406 | negative regulation of neuroblast proliferation(GO:0007406) |
| 0.1 | 0.3 | GO:0010424 | DNA methylation on cytosine within a CG sequence(GO:0010424) |
| 0.1 | 11.0 | GO:0007229 | integrin-mediated signaling pathway(GO:0007229) |
| 0.1 | 0.4 | GO:0008050 | female courtship behavior(GO:0008050) |
| 0.1 | 0.3 | GO:0072236 | metanephric loop of Henle development(GO:0072236) |
| 0.1 | 0.5 | GO:1903265 | positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265) |
| 0.1 | 0.8 | GO:0007296 | vitellogenesis(GO:0007296) |
| 0.1 | 2.2 | GO:0051382 | kinetochore assembly(GO:0051382) |
| 0.1 | 0.8 | GO:1903300 | negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300) |
| 0.1 | 1.4 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
| 0.1 | 0.9 | GO:0017185 | peptidyl-lysine hydroxylation(GO:0017185) |
| 0.1 | 0.8 | GO:0060008 | Sertoli cell differentiation(GO:0060008) |
| 0.1 | 5.1 | GO:0035307 | positive regulation of protein dephosphorylation(GO:0035307) |
| 0.1 | 0.4 | GO:1902915 | negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915) |
| 0.1 | 3.6 | GO:0030199 | collagen fibril organization(GO:0030199) |
| 0.1 | 0.4 | GO:0045925 | positive regulation of female receptivity(GO:0045925) |
| 0.1 | 0.7 | GO:0036066 | protein O-linked fucosylation(GO:0036066) |
| 0.1 | 0.5 | GO:0007320 | insemination(GO:0007320) |
| 0.1 | 1.1 | GO:0090267 | positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) |
| 0.1 | 0.5 | GO:0006297 | nucleotide-excision repair, DNA gap filling(GO:0006297) |
| 0.1 | 1.4 | GO:0021924 | cell proliferation in external granule layer(GO:0021924) cerebellar granule cell precursor proliferation(GO:0021930) |
| 0.1 | 0.7 | GO:0045671 | negative regulation of osteoclast differentiation(GO:0045671) |
| 0.1 | 1.5 | GO:0009048 | dosage compensation by inactivation of X chromosome(GO:0009048) |
| 0.1 | 0.9 | GO:0045721 | negative regulation of gluconeogenesis(GO:0045721) |
| 0.1 | 0.6 | GO:0044838 | cell quiescence(GO:0044838) |
| 0.1 | 0.3 | GO:0034770 | histone H4-K20 methylation(GO:0034770) |
| 0.1 | 0.6 | GO:0021562 | vestibulocochlear nerve development(GO:0021562) |
| 0.1 | 0.8 | GO:0098535 | de novo centriole assembly(GO:0098535) |
| 0.1 | 0.6 | GO:0002031 | G-protein coupled receptor internalization(GO:0002031) |
| 0.1 | 0.3 | GO:0010360 | negative regulation of anion channel activity(GO:0010360) |
| 0.1 | 0.6 | GO:0001840 | neural plate development(GO:0001840) |
| 0.1 | 0.4 | GO:0060459 | left lung development(GO:0060459) |
| 0.1 | 0.2 | GO:0045869 | negative regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045869) positive regulation of methylation-dependent chromatin silencing(GO:0090309) |
| 0.1 | 0.3 | GO:0051305 | chromosome movement towards spindle pole(GO:0051305) |
| 0.1 | 0.1 | GO:0014826 | vein smooth muscle contraction(GO:0014826) |
| 0.1 | 3.4 | GO:0007588 | excretion(GO:0007588) |
| 0.1 | 1.2 | GO:0048535 | lymph node development(GO:0048535) |
| 0.1 | 0.7 | GO:0061087 | positive regulation of histone H3-K27 methylation(GO:0061087) |
| 0.1 | 0.7 | GO:0008063 | Toll signaling pathway(GO:0008063) |
| 0.1 | 0.9 | GO:0001709 | cell fate determination(GO:0001709) |
| 0.1 | 0.5 | GO:2001168 | regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168) |
| 0.1 | 1.2 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) |
| 0.1 | 0.8 | GO:0030502 | negative regulation of bone mineralization(GO:0030502) |
| 0.1 | 0.7 | GO:0034214 | protein hexamerization(GO:0034214) |
| 0.1 | 2.3 | GO:2000651 | positive regulation of sodium ion transmembrane transporter activity(GO:2000651) |
| 0.1 | 3.7 | GO:0006284 | base-excision repair(GO:0006284) |
| 0.1 | 0.1 | GO:0072194 | ureter smooth muscle development(GO:0072191) ureter smooth muscle cell differentiation(GO:0072193) kidney smooth muscle tissue development(GO:0072194) |
| 0.1 | 0.7 | GO:0071459 | protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459) |
| 0.1 | 1.8 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 0.1 | 0.4 | GO:0032485 | regulation of Ral protein signal transduction(GO:0032485) |
| 0.1 | 0.5 | GO:1904251 | regulation of bile acid metabolic process(GO:1904251) |
| 0.1 | 2.9 | GO:0015804 | neutral amino acid transport(GO:0015804) |
| 0.1 | 2.2 | GO:0060441 | epithelial tube branching involved in lung morphogenesis(GO:0060441) |
| 0.1 | 0.2 | GO:0007197 | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207) |
| 0.1 | 0.3 | GO:1990839 | response to endothelin(GO:1990839) |
| 0.1 | 0.5 | GO:0072697 | protein localization to cell cortex(GO:0072697) |
| 0.1 | 0.2 | GO:0046851 | negative regulation of low-density lipoprotein particle clearance(GO:0010989) negative regulation of bone resorption(GO:0045779) negative regulation of bone remodeling(GO:0046851) |
| 0.1 | 0.3 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.1 | 2.1 | GO:0045070 | positive regulation of viral genome replication(GO:0045070) |
| 0.1 | 0.2 | GO:1903490 | regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490) |
| 0.1 | 0.4 | GO:0046541 | saliva secretion(GO:0046541) |
| 0.1 | 0.8 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.1 | 0.5 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
| 0.1 | 0.8 | GO:0000212 | meiotic spindle organization(GO:0000212) |
| 0.1 | 0.6 | GO:0097067 | cellular response to thyroid hormone stimulus(GO:0097067) |
| 0.1 | 0.3 | GO:0072015 | glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310) |
| 0.1 | 1.3 | GO:0043550 | regulation of lipid kinase activity(GO:0043550) |
| 0.1 | 0.7 | GO:0070475 | rRNA base methylation(GO:0070475) |
| 0.1 | 0.4 | GO:0006741 | NADP biosynthetic process(GO:0006741) |
| 0.1 | 0.5 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
| 0.1 | 0.2 | GO:0034351 | negative regulation of glial cell apoptotic process(GO:0034351) |
| 0.1 | 0.6 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) |
| 0.1 | 0.7 | GO:0032897 | negative regulation of viral transcription(GO:0032897) |
| 0.1 | 0.8 | GO:0060307 | regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307) |
| 0.1 | 0.4 | GO:0048742 | regulation of skeletal muscle fiber development(GO:0048742) |
| 0.1 | 1.8 | GO:0001947 | heart looping(GO:0001947) |
| 0.1 | 0.7 | GO:0006353 | DNA-templated transcription, termination(GO:0006353) |
| 0.1 | 0.9 | GO:0031297 | replication fork processing(GO:0031297) |
| 0.1 | 0.2 | GO:0042796 | snRNA transcription from RNA polymerase III promoter(GO:0042796) |
| 0.1 | 0.1 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.1 | 0.8 | GO:0006490 | oligosaccharide-lipid intermediate biosynthetic process(GO:0006490) |
| 0.1 | 0.7 | GO:0001916 | positive regulation of T cell mediated cytotoxicity(GO:0001916) |
| 0.1 | 0.5 | GO:0032682 | negative regulation of chemokine production(GO:0032682) |
| 0.1 | 5.3 | GO:0000082 | G1/S transition of mitotic cell cycle(GO:0000082) |
| 0.1 | 0.3 | GO:0060510 | Type II pneumocyte differentiation(GO:0060510) |
| 0.1 | 0.5 | GO:0015074 | DNA integration(GO:0015074) |
| 0.1 | 0.1 | GO:0060971 | embryonic heart tube left/right pattern formation(GO:0060971) |
| 0.1 | 0.9 | GO:0006465 | signal peptide processing(GO:0006465) |
| 0.1 | 0.2 | GO:0006116 | NADH oxidation(GO:0006116) |
| 0.1 | 0.2 | GO:0001771 | immunological synapse formation(GO:0001771) |
| 0.1 | 0.3 | GO:0003419 | growth plate cartilage chondrocyte proliferation(GO:0003419) |
| 0.1 | 0.3 | GO:0038031 | non-canonical Wnt signaling pathway via JNK cascade(GO:0038031) |
| 0.1 | 0.5 | GO:0042753 | positive regulation of circadian rhythm(GO:0042753) |
| 0.1 | 0.4 | GO:1902913 | regulation of melanocyte differentiation(GO:0045634) positive regulation of melanocyte differentiation(GO:0045636) positive regulation of neuroepithelial cell differentiation(GO:1902913) |
| 0.1 | 0.4 | GO:1900016 | negative regulation of cytokine production involved in inflammatory response(GO:1900016) |
| 0.0 | 0.3 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.0 | 0.3 | GO:0002741 | positive regulation of cytokine secretion involved in immune response(GO:0002741) |
| 0.0 | 0.7 | GO:0006415 | translational termination(GO:0006415) |
| 0.0 | 0.6 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 0.0 | 0.2 | GO:0010961 | cellular magnesium ion homeostasis(GO:0010961) |
| 0.0 | 0.5 | GO:0007130 | synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193) |
| 0.0 | 1.4 | GO:0045494 | photoreceptor cell maintenance(GO:0045494) |
| 0.0 | 0.5 | GO:0021702 | cerebellar Purkinje cell differentiation(GO:0021702) |
| 0.0 | 0.1 | GO:0070459 | prolactin secretion(GO:0070459) |
| 0.0 | 0.5 | GO:0050691 | regulation of defense response to virus by host(GO:0050691) |
| 0.0 | 0.4 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
| 0.0 | 0.8 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.0 | 0.2 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
| 0.0 | 4.2 | GO:0019722 | calcium-mediated signaling(GO:0019722) |
| 0.0 | 0.6 | GO:2000144 | positive regulation of DNA-templated transcription, initiation(GO:2000144) |
| 0.0 | 2.0 | GO:0030490 | maturation of SSU-rRNA(GO:0030490) |
| 0.0 | 1.1 | GO:0006379 | mRNA cleavage(GO:0006379) |
| 0.0 | 0.2 | GO:1902774 | late endosome to lysosome transport(GO:1902774) |
| 0.0 | 0.3 | GO:0045647 | negative regulation of erythrocyte differentiation(GO:0045647) |
| 0.0 | 1.1 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
| 0.0 | 0.2 | GO:0060575 | intestinal epithelial cell differentiation(GO:0060575) |
| 0.0 | 0.6 | GO:0043162 | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162) |
| 0.0 | 1.0 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
| 0.0 | 2.5 | GO:0048864 | stem cell development(GO:0048864) |
| 0.0 | 0.2 | GO:0045794 | negative regulation of cell volume(GO:0045794) |
| 0.0 | 1.2 | GO:0001885 | endothelial cell development(GO:0001885) |
| 0.0 | 0.3 | GO:0046085 | adenosine metabolic process(GO:0046085) |
| 0.0 | 0.1 | GO:0072189 | ureter development(GO:0072189) |
| 0.0 | 0.2 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
| 0.0 | 0.2 | GO:0014816 | skeletal muscle satellite cell differentiation(GO:0014816) positive regulation of myoblast proliferation(GO:2000288) |
| 0.0 | 1.0 | GO:0035458 | cellular response to interferon-beta(GO:0035458) |
| 0.0 | 1.0 | GO:0007218 | neuropeptide signaling pathway(GO:0007218) |
| 0.0 | 0.6 | GO:0034315 | regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315) |
| 0.0 | 0.1 | GO:1902174 | positive regulation of keratinocyte apoptotic process(GO:1902174) |
| 0.0 | 0.1 | GO:0006014 | D-ribose metabolic process(GO:0006014) |
| 0.0 | 0.4 | GO:2000114 | regulation of establishment of cell polarity(GO:2000114) |
| 0.0 | 0.5 | GO:0050892 | intestinal absorption(GO:0050892) |
| 0.0 | 0.3 | GO:0060052 | neurofilament cytoskeleton organization(GO:0060052) |
| 0.0 | 0.3 | GO:0030728 | ovulation(GO:0030728) |
| 0.0 | 0.6 | GO:0051764 | actin crosslink formation(GO:0051764) |
| 0.0 | 0.3 | GO:0016188 | synaptic vesicle maturation(GO:0016188) |
| 0.0 | 0.1 | GO:0002315 | marginal zone B cell differentiation(GO:0002315) |
| 0.0 | 0.1 | GO:0048665 | neuron fate specification(GO:0048665) |
| 0.0 | 0.1 | GO:0051533 | positive regulation of NFAT protein import into nucleus(GO:0051533) |
| 0.0 | 0.1 | GO:0071896 | protein localization to adherens junction(GO:0071896) |
| 0.0 | 0.2 | GO:0031339 | negative regulation of vesicle fusion(GO:0031339) |
| 0.0 | 0.2 | GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289) |
| 0.0 | 0.1 | GO:0007217 | tachykinin receptor signaling pathway(GO:0007217) |
| 0.0 | 0.5 | GO:0010842 | retina layer formation(GO:0010842) |
| 0.0 | 0.2 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.0 | 1.1 | GO:0032781 | positive regulation of ATPase activity(GO:0032781) |
| 0.0 | 0.2 | GO:0007131 | reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825) |
| 0.0 | 0.4 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
| 0.0 | 0.3 | GO:0009404 | toxin metabolic process(GO:0009404) |
| 0.0 | 0.2 | GO:0043518 | negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) |
| 0.0 | 0.5 | GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771) |
| 0.0 | 0.0 | GO:0046101 | hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101) |
| 0.0 | 1.2 | GO:0007200 | phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200) |
| 0.0 | 0.5 | GO:0045737 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) |
| 0.0 | 0.4 | GO:0045600 | positive regulation of fat cell differentiation(GO:0045600) |
| 0.0 | 0.3 | GO:0006107 | oxaloacetate metabolic process(GO:0006107) |
| 0.0 | 0.7 | GO:0060325 | face morphogenesis(GO:0060325) |
| 0.0 | 0.2 | GO:0071157 | negative regulation of cell cycle arrest(GO:0071157) |
| 0.0 | 0.2 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
| 0.0 | 0.4 | GO:0030224 | monocyte differentiation(GO:0030224) |
| 0.0 | 0.3 | GO:1900046 | regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046) |
| 0.0 | 0.3 | GO:0019731 | antibacterial humoral response(GO:0019731) |
| 0.0 | 0.3 | GO:0001573 | ganglioside metabolic process(GO:0001573) |
| 0.0 | 0.3 | GO:0043984 | histone H4-K16 acetylation(GO:0043984) |
| 0.0 | 0.5 | GO:1901224 | positive regulation of NIK/NF-kappaB signaling(GO:1901224) |
| 0.0 | 0.2 | GO:0030183 | B cell differentiation(GO:0030183) |
| 0.0 | 0.5 | GO:0006303 | double-strand break repair via nonhomologous end joining(GO:0006303) |
| 0.0 | 1.7 | GO:0006888 | ER to Golgi vesicle-mediated transport(GO:0006888) |
| 0.0 | 0.1 | GO:1901165 | positive regulation of trophoblast cell migration(GO:1901165) |
| 0.0 | 0.1 | GO:0070933 | histone H4 deacetylation(GO:0070933) |
| 0.0 | 0.4 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 0.0 | 1.2 | GO:0061077 | chaperone-mediated protein folding(GO:0061077) |
| 0.0 | 0.7 | GO:0009168 | purine nucleoside monophosphate biosynthetic process(GO:0009127) purine ribonucleoside monophosphate biosynthetic process(GO:0009168) |
| 0.0 | 0.6 | GO:0006405 | RNA export from nucleus(GO:0006405) |
| 0.0 | 0.3 | GO:0071364 | cellular response to epidermal growth factor stimulus(GO:0071364) |
| 0.0 | 0.0 | GO:0019085 | early viral transcription(GO:0019085) |
| 0.0 | 1.7 | GO:0008033 | tRNA processing(GO:0008033) |
| 0.0 | 0.3 | GO:0030520 | intracellular estrogen receptor signaling pathway(GO:0030520) |
| 0.0 | 0.3 | GO:0051443 | positive regulation of ubiquitin-protein transferase activity(GO:0051443) |
| 0.0 | 0.9 | GO:0045137 | development of primary sexual characteristics(GO:0045137) |
| 0.0 | 0.1 | GO:0089700 | protein kinase D signaling(GO:0089700) |
| 0.0 | 0.1 | GO:0001569 | patterning of blood vessels(GO:0001569) |
| 0.0 | 0.1 | GO:0031507 | heterochromatin assembly(GO:0031507) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.6 | 13.2 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
| 2.6 | 31.1 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 2.5 | 7.4 | GO:0097059 | CNTFR-CLCF1 complex(GO:0097059) |
| 1.2 | 3.7 | GO:0033186 | CAF-1 complex(GO:0033186) |
| 1.1 | 3.2 | GO:0097135 | cyclin E2-CDK2 complex(GO:0097135) |
| 1.0 | 6.9 | GO:0001740 | Barr body(GO:0001740) |
| 0.9 | 2.7 | GO:0000785 | chromatin(GO:0000785) |
| 0.8 | 3.4 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 0.8 | 2.3 | GO:0036387 | nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387) |
| 0.6 | 1.8 | GO:0005899 | insulin receptor complex(GO:0005899) |
| 0.6 | 2.3 | GO:0014802 | terminal cisterna(GO:0014802) |
| 0.5 | 8.1 | GO:0042555 | MCM complex(GO:0042555) |
| 0.5 | 4.5 | GO:0031254 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
| 0.5 | 3.4 | GO:0097452 | GAIT complex(GO:0097452) |
| 0.5 | 2.4 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 0.5 | 2.4 | GO:0005587 | collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651) |
| 0.5 | 2.7 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
| 0.4 | 1.3 | GO:0017109 | glutamate-cysteine ligase complex(GO:0017109) |
| 0.4 | 1.2 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.4 | 3.6 | GO:0000796 | condensin complex(GO:0000796) |
| 0.4 | 2.0 | GO:0016600 | flotillin complex(GO:0016600) |
| 0.4 | 1.9 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
| 0.4 | 2.3 | GO:0001674 | female germ cell nucleus(GO:0001674) |
| 0.4 | 1.1 | GO:0018444 | translation release factor complex(GO:0018444) |
| 0.4 | 1.5 | GO:0089717 | spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717) |
| 0.4 | 20.2 | GO:0000791 | euchromatin(GO:0000791) |
| 0.4 | 1.8 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
| 0.3 | 1.0 | GO:0031074 | nucleocytoplasmic shuttling complex(GO:0031074) |
| 0.3 | 5.2 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.3 | 4.0 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.3 | 0.9 | GO:0034457 | Mpp10 complex(GO:0034457) |
| 0.3 | 4.8 | GO:0065010 | extracellular membrane-bounded organelle(GO:0065010) |
| 0.3 | 5.5 | GO:0008305 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
| 0.3 | 1.5 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.2 | 0.7 | GO:0071595 | Nem1-Spo7 phosphatase complex(GO:0071595) |
| 0.2 | 7.3 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.2 | 1.4 | GO:0000235 | astral microtubule(GO:0000235) |
| 0.2 | 3.0 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 0.2 | 3.7 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.2 | 2.5 | GO:0032426 | stereocilium tip(GO:0032426) |
| 0.2 | 1.8 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.2 | 0.7 | GO:1990423 | Dsl1p complex(GO:0070939) RZZ complex(GO:1990423) |
| 0.2 | 4.1 | GO:0097470 | ribbon synapse(GO:0097470) |
| 0.2 | 1.3 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.2 | 1.1 | GO:0032585 | multivesicular body membrane(GO:0032585) |
| 0.2 | 2.7 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.2 | 1.0 | GO:0044301 | climbing fiber(GO:0044301) |
| 0.2 | 1.4 | GO:0044352 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 0.2 | 0.6 | GO:0031251 | PAN complex(GO:0031251) |
| 0.2 | 9.0 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.2 | 0.9 | GO:0001652 | granular component(GO:0001652) |
| 0.2 | 0.5 | GO:0000801 | central element(GO:0000801) |
| 0.2 | 1.0 | GO:0098536 | deuterosome(GO:0098536) |
| 0.2 | 0.8 | GO:0072487 | MSL complex(GO:0072487) |
| 0.2 | 1.1 | GO:0005638 | lamin filament(GO:0005638) |
| 0.2 | 1.4 | GO:0036157 | outer dynein arm(GO:0036157) |
| 0.2 | 0.9 | GO:0070776 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
| 0.2 | 0.8 | GO:0031390 | Ctf18 RFC-like complex(GO:0031390) |
| 0.2 | 2.6 | GO:0043596 | nuclear replication fork(GO:0043596) |
| 0.1 | 0.7 | GO:0034715 | pICln-Sm protein complex(GO:0034715) |
| 0.1 | 0.6 | GO:0032444 | activin responsive factor complex(GO:0032444) |
| 0.1 | 0.8 | GO:0000938 | GARP complex(GO:0000938) |
| 0.1 | 1.2 | GO:0005916 | fascia adherens(GO:0005916) |
| 0.1 | 4.0 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.1 | 1.3 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
| 0.1 | 0.5 | GO:0030289 | protein phosphatase 4 complex(GO:0030289) |
| 0.1 | 9.1 | GO:0005844 | polysome(GO:0005844) |
| 0.1 | 1.0 | GO:0071598 | neuronal ribonucleoprotein granule(GO:0071598) |
| 0.1 | 1.5 | GO:0030529 | intracellular ribonucleoprotein complex(GO:0030529) ribonucleoprotein complex(GO:1990904) |
| 0.1 | 0.8 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.1 | 0.9 | GO:0005787 | signal peptidase complex(GO:0005787) |
| 0.1 | 1.5 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
| 0.1 | 15.0 | GO:0005884 | actin filament(GO:0005884) |
| 0.1 | 0.3 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.1 | 3.7 | GO:0016592 | mediator complex(GO:0016592) |
| 0.1 | 1.0 | GO:0044294 | dendritic growth cone(GO:0044294) |
| 0.1 | 2.2 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.1 | 2.0 | GO:1990391 | DNA repair complex(GO:1990391) |
| 0.1 | 0.5 | GO:0071204 | histone pre-mRNA 3'end processing complex(GO:0071204) |
| 0.1 | 0.3 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.1 | 2.0 | GO:0005657 | replication fork(GO:0005657) |
| 0.1 | 1.6 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.1 | 1.4 | GO:0045120 | pronucleus(GO:0045120) |
| 0.1 | 0.7 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
| 0.1 | 2.1 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 0.1 | 0.9 | GO:0031011 | Ino80 complex(GO:0031011) |
| 0.1 | 0.7 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.1 | 0.2 | GO:0043540 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540) |
| 0.1 | 5.8 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.1 | 1.0 | GO:0005922 | connexon complex(GO:0005922) |
| 0.1 | 0.9 | GO:0005686 | U2 snRNP(GO:0005686) |
| 0.1 | 1.0 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
| 0.1 | 1.2 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.1 | 0.5 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
| 0.1 | 0.5 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
| 0.1 | 0.5 | GO:0097413 | Lewy body(GO:0097413) |
| 0.1 | 0.3 | GO:0097255 | R2TP complex(GO:0097255) |
| 0.1 | 0.5 | GO:0031415 | NatA complex(GO:0031415) |
| 0.1 | 0.4 | GO:0060293 | P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293) |
| 0.1 | 13.7 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.1 | 3.4 | GO:0014704 | intercalated disc(GO:0014704) |
| 0.1 | 9.9 | GO:0044798 | nuclear transcription factor complex(GO:0044798) |
| 0.1 | 4.7 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.1 | 0.3 | GO:0070876 | SOSS complex(GO:0070876) |
| 0.1 | 0.6 | GO:0046540 | U4/U6 x U5 tri-snRNP complex(GO:0046540) |
| 0.1 | 0.2 | GO:0097629 | extrinsic component of omegasome membrane(GO:0097629) |
| 0.1 | 0.8 | GO:1904115 | axon cytoplasm(GO:1904115) |
| 0.0 | 0.3 | GO:0010369 | chromocenter(GO:0010369) |
| 0.0 | 1.4 | GO:0032040 | small-subunit processome(GO:0032040) |
| 0.0 | 0.3 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.0 | 1.1 | GO:0044815 | DNA packaging complex(GO:0044815) |
| 0.0 | 3.1 | GO:0000784 | nuclear chromosome, telomeric region(GO:0000784) |
| 0.0 | 0.1 | GO:0097543 | ciliary inversin compartment(GO:0097543) |
| 0.0 | 0.4 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.0 | 1.3 | GO:0060170 | ciliary membrane(GO:0060170) |
| 0.0 | 1.4 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
| 0.0 | 0.5 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.0 | 1.0 | GO:0032587 | ruffle membrane(GO:0032587) |
| 0.0 | 0.9 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.0 | 1.8 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 0.3 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
| 0.0 | 0.3 | GO:1990909 | Wnt signalosome(GO:1990909) |
| 0.0 | 0.1 | GO:0034709 | methylosome(GO:0034709) |
| 0.0 | 0.2 | GO:0046930 | pore complex(GO:0046930) |
| 0.0 | 0.8 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.0 | 2.5 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 0.0 | 3.7 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.0 | 0.2 | GO:0016272 | prefoldin complex(GO:0016272) |
| 0.0 | 1.1 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.0 | 0.7 | GO:0032993 | protein-DNA complex(GO:0032993) |
| 0.0 | 1.0 | GO:0016235 | aggresome(GO:0016235) |
| 0.0 | 0.2 | GO:0031931 | TORC1 complex(GO:0031931) |
| 0.0 | 0.6 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.0 | 0.1 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 0.0 | 0.3 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.0 | 0.5 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.0 | 2.0 | GO:0005903 | brush border(GO:0005903) |
| 0.0 | 0.3 | GO:0002102 | podosome(GO:0002102) |
| 0.0 | 1.1 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 1.1 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
| 0.0 | 1.1 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.0 | 0.7 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.0 | 0.4 | GO:0035869 | ciliary transition zone(GO:0035869) |
| 0.0 | 0.2 | GO:0035631 | CD40 receptor complex(GO:0035631) |
| 0.0 | 0.3 | GO:0000242 | pericentriolar material(GO:0000242) |
| 0.0 | 0.2 | GO:0043220 | Schmidt-Lanterman incisure(GO:0043220) |
| 0.0 | 0.0 | GO:0000779 | condensed chromosome, centromeric region(GO:0000779) |
| 0.0 | 0.1 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
| 0.0 | 0.6 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.0 | 2.0 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.0 | 0.2 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
| 0.0 | 0.1 | GO:0032009 | early phagosome(GO:0032009) |
| 0.0 | 0.2 | GO:0032279 | asymmetric synapse(GO:0032279) |
| 0.0 | 0.2 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.0 | 0.4 | GO:0044452 | nucleolar part(GO:0044452) |
| 0.0 | 0.0 | GO:0002189 | ribose phosphate diphosphokinase complex(GO:0002189) |
| 0.0 | 0.2 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.0 | 0.2 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.0 | 0.9 | GO:0000502 | proteasome complex(GO:0000502) |
| 0.0 | 0.1 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.0 | 0.2 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.0 | 0.1 | GO:0090543 | Flemming body(GO:0090543) |
| 0.0 | 0.7 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.9 | 29.3 | GO:0042289 | MHC class II protein binding(GO:0042289) |
| 2.6 | 13.2 | GO:0061731 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
| 1.7 | 6.9 | GO:0044729 | hemi-methylated DNA-binding(GO:0044729) |
| 1.7 | 5.1 | GO:0015403 | thiamine uptake transmembrane transporter activity(GO:0015403) |
| 1.6 | 9.8 | GO:0043426 | MRF binding(GO:0043426) |
| 1.4 | 6.8 | GO:0019828 | aspartic-type endopeptidase inhibitor activity(GO:0019828) |
| 1.3 | 4.0 | GO:0035939 | microsatellite binding(GO:0035939) |
| 1.3 | 3.8 | GO:0005105 | type 1 fibroblast growth factor receptor binding(GO:0005105) |
| 1.2 | 7.4 | GO:0004897 | ciliary neurotrophic factor receptor activity(GO:0004897) |
| 1.2 | 4.8 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
| 1.2 | 9.5 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 1.2 | 7.0 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
| 1.0 | 7.1 | GO:0034056 | estrogen response element binding(GO:0034056) |
| 0.9 | 3.7 | GO:0004844 | uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506) |
| 0.9 | 3.6 | GO:0038049 | glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
| 0.9 | 4.4 | GO:0005113 | patched binding(GO:0005113) |
| 0.8 | 2.4 | GO:0070052 | collagen V binding(GO:0070052) |
| 0.8 | 4.0 | GO:0043515 | kinetochore binding(GO:0043515) |
| 0.8 | 5.5 | GO:0016618 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
| 0.7 | 26.4 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.7 | 4.3 | GO:0003910 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
| 0.7 | 2.0 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
| 0.7 | 5.4 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
| 0.6 | 1.9 | GO:0008310 | single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310) |
| 0.6 | 3.2 | GO:0070320 | inward rectifier potassium channel inhibitor activity(GO:0070320) |
| 0.6 | 1.9 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
| 0.6 | 5.6 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
| 0.6 | 2.5 | GO:0004706 | JUN kinase kinase kinase activity(GO:0004706) |
| 0.6 | 3.6 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
| 0.6 | 0.6 | GO:0010484 | H3 histone acetyltransferase activity(GO:0010484) |
| 0.5 | 1.5 | GO:0086077 | gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077) |
| 0.5 | 1.4 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
| 0.4 | 1.3 | GO:0004357 | glutamate-cysteine ligase activity(GO:0004357) |
| 0.4 | 2.5 | GO:0071074 | eukaryotic initiation factor eIF2 binding(GO:0071074) |
| 0.4 | 2.9 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.4 | 3.3 | GO:0001075 | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) |
| 0.4 | 3.3 | GO:0047429 | nucleoside-triphosphate diphosphatase activity(GO:0047429) |
| 0.4 | 1.6 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.4 | 3.1 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
| 0.4 | 1.1 | GO:0031779 | melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782) |
| 0.4 | 4.5 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.3 | 2.1 | GO:0015204 | urea transmembrane transporter activity(GO:0015204) |
| 0.3 | 4.2 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) |
| 0.3 | 8.3 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
| 0.3 | 1.4 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
| 0.3 | 3.4 | GO:0070700 | BMP receptor binding(GO:0070700) |
| 0.3 | 2.0 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
| 0.3 | 1.3 | GO:0016812 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812) |
| 0.3 | 3.5 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 0.3 | 9.7 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.3 | 5.3 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.3 | 1.6 | GO:1990188 | euchromatin binding(GO:1990188) |
| 0.3 | 8.9 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.3 | 1.5 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.3 | 1.5 | GO:0001165 | RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165) |
| 0.3 | 4.0 | GO:0030957 | Tat protein binding(GO:0030957) |
| 0.3 | 6.5 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.3 | 2.0 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 0.3 | 1.7 | GO:0008296 | 3'-5'-exodeoxyribonuclease activity(GO:0008296) |
| 0.3 | 0.8 | GO:0000033 | alpha-1,3-mannosyltransferase activity(GO:0000033) |
| 0.3 | 2.2 | GO:0003747 | translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079) |
| 0.3 | 0.8 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |
| 0.3 | 2.1 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
| 0.3 | 2.3 | GO:0034711 | inhibin binding(GO:0034711) |
| 0.3 | 10.5 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.2 | 1.2 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
| 0.2 | 1.9 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
| 0.2 | 2.6 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 0.2 | 0.7 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
| 0.2 | 4.2 | GO:0010485 | H4 histone acetyltransferase activity(GO:0010485) |
| 0.2 | 1.8 | GO:0098632 | protein binding involved in cell-cell adhesion(GO:0098632) |
| 0.2 | 1.1 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
| 0.2 | 0.9 | GO:0001537 | N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537) |
| 0.2 | 1.7 | GO:0046790 | virion binding(GO:0046790) |
| 0.2 | 0.6 | GO:0017153 | sodium:dicarboxylate symporter activity(GO:0017153) |
| 0.2 | 1.2 | GO:0045340 | mercury ion binding(GO:0045340) |
| 0.2 | 1.8 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
| 0.2 | 2.4 | GO:0050692 | DBD domain binding(GO:0050692) |
| 0.2 | 0.8 | GO:1902379 | chemoattractant activity involved in axon guidance(GO:1902379) |
| 0.2 | 2.9 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.2 | 0.6 | GO:0098770 | FBXO family protein binding(GO:0098770) |
| 0.2 | 5.4 | GO:0071837 | HMG box domain binding(GO:0071837) |
| 0.2 | 0.6 | GO:0043199 | sulfate binding(GO:0043199) |
| 0.2 | 0.8 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
| 0.2 | 0.9 | GO:0030620 | U2 snRNA binding(GO:0030620) |
| 0.2 | 1.8 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
| 0.2 | 1.3 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
| 0.2 | 4.2 | GO:0045505 | dynein intermediate chain binding(GO:0045505) |
| 0.2 | 0.9 | GO:0070815 | peptidyl-lysine 5-dioxygenase activity(GO:0070815) |
| 0.2 | 0.5 | GO:0071207 | histone pre-mRNA stem-loop binding(GO:0071207) |
| 0.2 | 1.4 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
| 0.2 | 3.8 | GO:0070410 | co-SMAD binding(GO:0070410) |
| 0.2 | 2.2 | GO:0008484 | sulfuric ester hydrolase activity(GO:0008484) |
| 0.2 | 2.5 | GO:0015026 | coreceptor activity(GO:0015026) |
| 0.2 | 2.3 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.2 | 0.5 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.2 | 2.1 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.2 | 3.0 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.2 | 2.1 | GO:0055106 | ubiquitin-protein transferase regulator activity(GO:0055106) |
| 0.2 | 1.0 | GO:0008494 | translation activator activity(GO:0008494) |
| 0.2 | 2.5 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
| 0.2 | 0.6 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
| 0.2 | 1.7 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.2 | 0.5 | GO:0008515 | sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157) |
| 0.2 | 3.3 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
| 0.1 | 2.1 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 0.1 | 2.8 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.1 | 0.4 | GO:0003987 | acetate-CoA ligase activity(GO:0003987) |
| 0.1 | 1.6 | GO:0015093 | ferrous iron transmembrane transporter activity(GO:0015093) |
| 0.1 | 3.6 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
| 0.1 | 3.4 | GO:0016881 | acid-amino acid ligase activity(GO:0016881) |
| 0.1 | 2.0 | GO:0043495 | protein anchor(GO:0043495) |
| 0.1 | 3.0 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 0.1 | 0.5 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
| 0.1 | 1.1 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
| 0.1 | 7.3 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
| 0.1 | 5.2 | GO:0070888 | E-box binding(GO:0070888) |
| 0.1 | 0.6 | GO:0001047 | core promoter binding(GO:0001047) |
| 0.1 | 2.3 | GO:0005003 | ephrin receptor activity(GO:0005003) |
| 0.1 | 0.1 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
| 0.1 | 0.7 | GO:0023029 | MHC class Ib protein binding(GO:0023029) |
| 0.1 | 4.4 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.1 | 0.8 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 0.1 | 1.0 | GO:0030976 | thiamine pyrophosphate binding(GO:0030976) |
| 0.1 | 0.4 | GO:0051022 | Rho GDP-dissociation inhibitor binding(GO:0051022) |
| 0.1 | 0.3 | GO:0048408 | epidermal growth factor binding(GO:0048408) |
| 0.1 | 11.4 | GO:0005178 | integrin binding(GO:0005178) |
| 0.1 | 1.2 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.1 | 1.3 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.1 | 7.3 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
| 0.1 | 1.9 | GO:0034483 | heparan sulfate sulfotransferase activity(GO:0034483) |
| 0.1 | 1.2 | GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.1 | 0.4 | GO:0004703 | G-protein coupled receptor kinase activity(GO:0004703) |
| 0.1 | 0.4 | GO:0070976 | TIR domain binding(GO:0070976) |
| 0.1 | 2.3 | GO:0019789 | SUMO transferase activity(GO:0019789) |
| 0.1 | 0.7 | GO:0046965 | retinoid X receptor binding(GO:0046965) |
| 0.1 | 0.3 | GO:0097108 | hedgehog family protein binding(GO:0097108) |
| 0.1 | 3.9 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.1 | 0.4 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
| 0.1 | 0.5 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.1 | 1.8 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
| 0.1 | 8.2 | GO:0001085 | RNA polymerase II transcription factor binding(GO:0001085) |
| 0.1 | 0.4 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 0.1 | 0.8 | GO:0043394 | proteoglycan binding(GO:0043394) |
| 0.1 | 0.2 | GO:0000983 | transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983) |
| 0.1 | 4.0 | GO:0031593 | polyubiquitin binding(GO:0031593) |
| 0.1 | 0.3 | GO:0004692 | cGMP-dependent protein kinase activity(GO:0004692) |
| 0.1 | 0.2 | GO:0042287 | MHC protein binding(GO:0042287) |
| 0.1 | 2.0 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.1 | 14.6 | GO:0042393 | histone binding(GO:0042393) |
| 0.1 | 1.3 | GO:0001530 | lipopolysaccharide binding(GO:0001530) |
| 0.1 | 0.7 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
| 0.1 | 0.6 | GO:0042609 | CD4 receptor binding(GO:0042609) |
| 0.1 | 1.1 | GO:0008432 | JUN kinase binding(GO:0008432) |
| 0.1 | 0.5 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 0.1 | 0.2 | GO:0051425 | PTB domain binding(GO:0051425) |
| 0.1 | 0.8 | GO:0009922 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.1 | 0.4 | GO:0071253 | connexin binding(GO:0071253) |
| 0.1 | 0.6 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
| 0.1 | 0.5 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
| 0.1 | 1.6 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.1 | 4.6 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
| 0.1 | 36.9 | GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) |
| 0.1 | 2.9 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
| 0.1 | 0.7 | GO:0031996 | thioesterase binding(GO:0031996) |
| 0.1 | 2.5 | GO:0070063 | RNA polymerase binding(GO:0070063) |
| 0.1 | 0.5 | GO:0016428 | tRNA (cytosine-5-)-methyltransferase activity(GO:0016428) |
| 0.1 | 0.5 | GO:0035312 | 5'-3' exodeoxyribonuclease activity(GO:0035312) |
| 0.1 | 1.2 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.1 | 1.7 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.1 | 1.0 | GO:0033613 | activating transcription factor binding(GO:0033613) |
| 0.1 | 0.7 | GO:0004576 | oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.0 | 0.2 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
| 0.0 | 0.5 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 0.0 | 2.6 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 0.3 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
| 0.0 | 0.2 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.0 | 11.0 | GO:0043565 | sequence-specific DNA binding(GO:0043565) |
| 0.0 | 1.1 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
| 0.0 | 0.3 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
| 0.0 | 0.9 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
| 0.0 | 0.7 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 0.0 | 0.9 | GO:0005112 | Notch binding(GO:0005112) |
| 0.0 | 0.3 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
| 0.0 | 1.1 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 0.3 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.0 | 0.4 | GO:0005521 | lamin binding(GO:0005521) |
| 0.0 | 0.7 | GO:0008483 | transaminase activity(GO:0008483) |
| 0.0 | 0.2 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 0.0 | 0.2 | GO:1990932 | 5.8S rRNA binding(GO:1990932) |
| 0.0 | 0.5 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.0 | 0.3 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) phosphatidylinositol bisphosphate binding(GO:1902936) |
| 0.0 | 1.3 | GO:0003682 | chromatin binding(GO:0003682) |
| 0.0 | 1.2 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 0.0 | 0.6 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.0 | 0.2 | GO:0008417 | fucosyltransferase activity(GO:0008417) |
| 0.0 | 1.8 | GO:0008083 | growth factor activity(GO:0008083) |
| 0.0 | 0.2 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
| 0.0 | 0.2 | GO:0003873 | 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) |
| 0.0 | 0.4 | GO:0048038 | quinone binding(GO:0048038) |
| 0.0 | 0.3 | GO:0005522 | profilin binding(GO:0005522) |
| 0.0 | 1.1 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650) |
| 0.0 | 0.0 | GO:0044020 | histone methyltransferase activity (H4-R3 specific)(GO:0044020) |
| 0.0 | 0.1 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
| 0.0 | 1.3 | GO:0051287 | NAD binding(GO:0051287) |
| 0.0 | 0.2 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 0.0 | 3.9 | GO:0044822 | mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822) |
| 0.0 | 0.1 | GO:0042285 | UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285) |
| 0.0 | 1.6 | GO:0017048 | Rho GTPase binding(GO:0017048) |
| 0.0 | 0.2 | GO:0048156 | tau protein binding(GO:0048156) |
| 0.0 | 0.1 | GO:0031752 | D5 dopamine receptor binding(GO:0031752) |
| 0.0 | 0.4 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.0 | 0.2 | GO:0048531 | beta-1,3-galactosyltransferase activity(GO:0048531) |
| 0.0 | 0.3 | GO:0031369 | translation initiation factor binding(GO:0031369) |
| 0.0 | 1.2 | GO:0003714 | transcription corepressor activity(GO:0003714) |
| 0.0 | 0.5 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.0 | 0.9 | GO:0031072 | heat shock protein binding(GO:0031072) |
| 0.0 | 0.4 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.0 | 0.2 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.0 | 0.2 | GO:0030971 | receptor tyrosine kinase binding(GO:0030971) |
| 0.0 | 0.1 | GO:0035174 | histone serine kinase activity(GO:0035174) |
| 0.0 | 1.0 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 0.1 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
| 0.0 | 1.6 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.0 | 0.4 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
| 0.0 | 0.0 | GO:0004749 | ribose phosphate diphosphokinase activity(GO:0004749) |
| 0.0 | 0.2 | GO:0003951 | NAD+ kinase activity(GO:0003951) |
| 0.0 | 0.5 | GO:0019843 | rRNA binding(GO:0019843) |
| 0.0 | 0.2 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 12.7 | SA_REG_CASCADE_OF_CYCLIN_EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.8 | 0.8 | SA_TRKA_RECEPTOR | The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. |
| 0.7 | 50.1 | PID_INTEGRIN1_PATHWAY | Beta1 integrin cell surface interactions |
| 0.7 | 13.0 | PID_CIRCADIAN_PATHWAY | Circadian rhythm pathway |
| 0.5 | 5.8 | PID_INTEGRIN5_PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.4 | 16.7 | PID_ATR_PATHWAY | ATR signaling pathway |
| 0.4 | 10.9 | PID_SMAD2_3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.4 | 28.8 | PID_E2F_PATHWAY | E2F transcription factor network |
| 0.3 | 3.4 | PID_ALK2_PATHWAY | ALK2 signaling events |
| 0.3 | 6.4 | PID_ALK1_PATHWAY | ALK1 signaling events |
| 0.3 | 23.3 | PID_SMAD2_3NUCLEAR_PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.3 | 13.6 | PID_WNT_NONCANONICAL_PATHWAY | Noncanonical Wnt signaling pathway |
| 0.3 | 15.1 | PID_ECADHERIN_STABILIZATION_PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.3 | 2.3 | PID_GLYPICAN_1PATHWAY | Glypican 1 network |
| 0.2 | 4.9 | PID_NEPHRIN_NEPH1_PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
| 0.2 | 6.0 | PID_RET_PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.2 | 1.0 | SA_G1_AND_S_PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 0.2 | 3.3 | PID_PRL_SIGNALING_EVENTS_PATHWAY | Signaling events mediated by PRL |
| 0.2 | 9.5 | PID_FGF_PATHWAY | FGF signaling pathway |
| 0.2 | 4.0 | PID_HEDGEHOG_2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.2 | 2.7 | PID_TCR_PATHWAY | TCR signaling in naïve CD4+ T cells |
| 0.2 | 8.4 | PID_MYC_REPRESS_PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.2 | 7.5 | PID_HES_HEY_PATHWAY | Notch-mediated HES/HEY network |
| 0.2 | 2.9 | PID_S1P_S1P2_PATHWAY | S1P2 pathway |
| 0.2 | 5.4 | PID_EPHRINB_REV_PATHWAY | Ephrin B reverse signaling |
| 0.1 | 0.9 | PID_IL5_PATHWAY | IL5-mediated signaling events |
| 0.1 | 4.6 | PID_DELTA_NP63_PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.1 | 1.4 | PID_RANBP2_PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.1 | 13.7 | PID_MYC_ACTIV_PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.1 | 8.5 | PID_AR_PATHWAY | Coregulation of Androgen receptor activity |
| 0.1 | 7.0 | PID_NOTCH_PATHWAY | Notch signaling pathway |
| 0.1 | 6.3 | PID_CMYB_PATHWAY | C-MYB transcription factor network |
| 0.1 | 3.5 | PID_HNF3B_PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.1 | 3.3 | PID_IL4_2PATHWAY | IL4-mediated signaling events |
| 0.1 | 1.1 | PID_NFKAPPAB_ATYPICAL_PATHWAY | Atypical NF-kappaB pathway |
| 0.1 | 1.9 | PID_FOXM1_PATHWAY | FOXM1 transcription factor network |
| 0.1 | 4.0 | PID_AURORA_B_PATHWAY | Aurora B signaling |
| 0.1 | 3.3 | PID_RHOA_PATHWAY | RhoA signaling pathway |
| 0.1 | 0.8 | PID_NECTIN_PATHWAY | Nectin adhesion pathway |
| 0.1 | 1.3 | PID_ERBB2_ERBB3_PATHWAY | ErbB2/ErbB3 signaling events |
| 0.1 | 2.3 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
| 0.1 | 1.9 | SIG_CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.1 | 2.1 | PID_IL12_2PATHWAY | IL12-mediated signaling events |
| 0.1 | 1.4 | PID_FAS_PATHWAY | FAS (CD95) signaling pathway |
| 0.1 | 1.1 | PID_HDAC_CLASSII_PATHWAY | Signaling events mediated by HDAC Class II |
| 0.1 | 1.8 | PID_BMP_PATHWAY | BMP receptor signaling |
| 0.1 | 0.4 | PID_SYNDECAN_2_PATHWAY | Syndecan-2-mediated signaling events |
| 0.1 | 1.4 | PID_TELOMERASE_PATHWAY | Regulation of Telomerase |
| 0.1 | 1.4 | PID_FAK_PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.1 | 2.3 | PID_ERA_GENOMIC_PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.1 | 2.2 | PID_CASPASE_PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 0.9 | PID_BARD1_PATHWAY | BARD1 signaling events |
| 0.0 | 0.4 | SIG_CHEMOTAXIS | Genes related to chemotaxis |
| 0.0 | 1.2 | PID_AJDISS_2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.0 | 1.7 | PID_HDAC_CLASSI_PATHWAY | Signaling events mediated by HDAC Class I |
| 0.0 | 0.6 | PID_TCR_CALCIUM_PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.0 | 4.7 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 0.6 | PID_IL6_7_PATHWAY | IL6-mediated signaling events |
| 0.0 | 0.1 | ST_JAK_STAT_PATHWAY | Jak-STAT Pathway |
| 0.0 | 0.6 | PID_ATM_PATHWAY | ATM pathway |
| 0.0 | 0.2 | PID_INSULIN_GLUCOSE_PATHWAY | Insulin-mediated glucose transport |
| 0.0 | 0.4 | PID_P38_ALPHA_BETA_PATHWAY | Regulation of p38-alpha and p38-beta |
| 0.0 | 0.4 | PID_CXCR4_PATHWAY | CXCR4-mediated signaling events |
| 0.0 | 0.2 | PID_NFAT_TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.0 | 0.3 | PID_HEDGEHOG_GLI_PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.0 | 1.8 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 0.4 | PID_PLK1_PATHWAY | PLK1 signaling events |
| 0.0 | 0.4 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.1 | 4.1 | REACTOME_SIGNALING_BY_FGFR3_MUTANTS | Genes involved in Signaling by FGFR3 mutants |
| 1.0 | 12.6 | REACTOME_ACTIVATED_POINT_MUTANTS_OF_FGFR2 | Genes involved in Activated point mutants of FGFR2 |
| 1.0 | 19.3 | REACTOME_G1_S_SPECIFIC_TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 0.8 | 10.1 | REACTOME_PROCESSIVE_SYNTHESIS_ON_THE_LAGGING_STRAND | Genes involved in Processive synthesis on the lagging strand |
| 0.7 | 32.2 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.6 | 12.6 | REACTOME_HS_GAG_DEGRADATION | Genes involved in HS-GAG degradation |
| 0.5 | 7.4 | REACTOME_UNWINDING_OF_DNA | Genes involved in Unwinding of DNA |
| 0.5 | 3.3 | REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
| 0.4 | 5.7 | REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 0.4 | 2.8 | REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER | Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER |
| 0.4 | 13.3 | REACTOME_PACKAGING_OF_TELOMERE_ENDS | Genes involved in Packaging Of Telomere Ends |
| 0.4 | 6.1 | REACTOME_G0_AND_EARLY_G1 | Genes involved in G0 and Early G1 |
| 0.3 | 2.0 | REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.3 | 3.7 | REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 0.3 | 4.2 | REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.3 | 2.1 | REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
| 0.3 | 13.1 | REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.3 | 2.2 | REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
| 0.3 | 1.8 | REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 0.2 | 3.6 | REACTOME_ACTIVATION_OF_RAC | Genes involved in Activation of Rac |
| 0.2 | 4.6 | REACTOME_PYRIMIDINE_METABOLISM | Genes involved in Pyrimidine metabolism |
| 0.2 | 5.4 | REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.2 | 6.6 | REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
| 0.2 | 1.5 | REACTOME_ENDOGENOUS_STEROLS | Genes involved in Endogenous sterols |
| 0.2 | 2.4 | REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY | Genes involved in Notch-HLH transcription pathway |
| 0.2 | 4.2 | REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.2 | 4.4 | REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.2 | 5.3 | REACTOME_G1_PHASE | Genes involved in G1 Phase |
| 0.2 | 4.4 | REACTOME_SIGNALING_BY_BMP | Genes involved in Signaling by BMP |
| 0.2 | 1.8 | REACTOME_IL_6_SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.1 | 2.1 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.1 | 10.9 | REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.1 | 0.8 | REACTOME_TRYPTOPHAN_CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.1 | 1.4 | REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTERGRINS_ | Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins |
| 0.1 | 0.2 | REACTOME_PLATELET_AGGREGATION_PLUG_FORMATION | Genes involved in Platelet Aggregation (Plug Formation) |
| 0.1 | 2.4 | REACTOME_SIGNAL_ATTENUATION | Genes involved in Signal attenuation |
| 0.1 | 1.0 | REACTOME_PURINE_CATABOLISM | Genes involved in Purine catabolism |
| 0.1 | 3.0 | REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.1 | 3.4 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.1 | 2.0 | REACTOME_RNA_POL_I_PROMOTER_OPENING | Genes involved in RNA Polymerase I Promoter Opening |
| 0.1 | 0.6 | REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION | Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation |
| 0.1 | 1.1 | REACTOME_AMINE_DERIVED_HORMONES | Genes involved in Amine-derived hormones |
| 0.1 | 1.4 | REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.1 | 1.8 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.1 | 0.8 | REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
| 0.1 | 1.1 | REACTOME_RAP1_SIGNALLING | Genes involved in Rap1 signalling |
| 0.1 | 1.0 | REACTOME_P75NTR_RECRUITS_SIGNALLING_COMPLEXES | Genes involved in p75NTR recruits signalling complexes |
| 0.1 | 1.0 | REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
| 0.1 | 0.7 | REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY | Genes involved in TRAF3-dependent IRF activation pathway |
| 0.1 | 1.0 | REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 0.1 | 2.0 | REACTOME_TRAF6_MEDIATED_NFKB_ACTIVATION | Genes involved in TRAF6 mediated NF-kB activation |
| 0.1 | 0.6 | REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
| 0.1 | 1.9 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.1 | 2.9 | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.1 | 1.0 | REACTOME_GAP_JUNCTION_ASSEMBLY | Genes involved in Gap junction assembly |
| 0.1 | 2.5 | REACTOME_SMOOTH_MUSCLE_CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.1 | 4.5 | REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.1 | 0.5 | REACTOME_REGULATION_OF_IFNG_SIGNALING | Genes involved in Regulation of IFNG signaling |
| 0.1 | 1.1 | REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.1 | 1.1 | REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX | Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex |
| 0.1 | 1.5 | REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |
| 0.1 | 0.6 | REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.1 | 1.5 | REACTOME_REGULATORY_RNA_PATHWAYS | Genes involved in Regulatory RNA pathways |
| 0.1 | 0.9 | REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1 | Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1) |
| 0.1 | 0.8 | REACTOME_EGFR_DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.1 | 1.0 | REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
| 0.1 | 0.8 | REACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE | Genes involved in Formation of Fibrin Clot (Clotting Cascade) |
| 0.1 | 1.9 | REACTOME_GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.1 | 1.3 | REACTOME_GLUTATHIONE_CONJUGATION | Genes involved in Glutathione conjugation |
| 0.0 | 0.6 | REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT | Genes involved in Regulation of beta-cell development |
| 0.0 | 5.2 | REACTOME_MRNA_SPLICING | Genes involved in mRNA Splicing |
| 0.0 | 1.9 | REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.0 | 4.0 | REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS | Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements |
| 0.0 | 0.9 | REACTOME_SIGNALING_BY_HIPPO | Genes involved in Signaling by Hippo |
| 0.0 | 6.9 | REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.0 | 0.4 | REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 0.0 | 0.8 | REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
| 0.0 | 3.1 | REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION | Genes involved in Influenza Viral RNA Transcription and Replication |
| 0.0 | 0.3 | REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 0.0 | 0.2 | REACTOME_ELONGATION_ARREST_AND_RECOVERY | Genes involved in Elongation arrest and recovery |
| 0.0 | 0.5 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 0.0 | 0.2 | REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 0.0 | 0.4 | REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.0 | 0.7 | REACTOME_SYNTHESIS_OF_PA | Genes involved in Synthesis of PA |
| 0.0 | 0.2 | REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |
| 0.0 | 0.3 | REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES | Genes involved in Generation of second messenger molecules |
| 0.0 | 0.9 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.0 | 0.3 | REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.0 | 0.1 | REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR | Genes involved in Thromboxane signalling through TP receptor |
| 0.0 | 0.2 | REACTOME_METABOLISM_OF_NON_CODING_RNA | Genes involved in Metabolism of non-coding RNA |
| 0.0 | 0.4 | REACTOME_MYOGENESIS | Genes involved in Myogenesis |
| 0.0 | 0.3 | REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.0 | 0.3 | REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
