Motif ID: Elf5

Z-value: 0.721


Transcription factors associated with Elf5:

Gene SymbolEntrez IDGene Name
Elf5 ENSMUSG00000027186.8 Elf5



Activity profile for motif Elf5.

activity profile for motif Elf5


Sorted Z-values histogram for motif Elf5

Sorted Z-values for motif Elf5



Network of associatons between targets according to the STRING database.



First level regulatory network of Elf5

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_-_76556662 2.459 ENSMUST00000064517.7
 Serp2
stress-associated endoplasmic reticulum protein family member 2
chr17_+_22689771 2.303 ENSMUST00000055305.8
 Gm9805
predicted gene 9805
chr6_-_23248264 2.164 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr3_+_95526777 1.861 ENSMUST00000015667.2
ENSMUST00000116304.2
 Ctss

cathepsin S

chr4_-_136886187 1.725 ENSMUST00000046384.8
 C1qb
complement component 1, q subcomponent, beta polypeptide
chr1_-_79440039 1.632 ENSMUST00000049972.4
 Scg2
secretogranin II
chr8_+_125995102 1.615 ENSMUST00000046765.8
 Kcnk1
potassium channel, subfamily K, member 1
chr2_+_104886318 1.574 ENSMUST00000111114.1
 Ccdc73
coiled-coil domain containing 73
chr3_+_95217417 1.500 ENSMUST00000181819.1
 Gm16740
predicted gene, 16740
chr18_+_62548911 1.468 ENSMUST00000055725.4
ENSMUST00000162365.1
 Spink10

serine peptidase inhibitor, Kazal type 10

chr12_+_77238093 1.465 ENSMUST00000177595.1
ENSMUST00000171770.2
 Fut8

fucosyltransferase 8

chr11_-_53430417 1.372 ENSMUST00000109019.1
 Uqcrq
ubiquinol-cytochrome c reductase, complex III subunit VII
chr5_+_122391878 1.324 ENSMUST00000102525.4
 Arpc3
actin related protein 2/3 complex, subunit 3
chr17_-_56133817 1.298 ENSMUST00000167545.1
 Sema6b
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr17_+_8311101 1.296 ENSMUST00000154553.1
 Sft2d1
SFT2 domain containing 1
chr12_+_112760652 1.292 ENSMUST00000063888.3
 Pld4
phospholipase D family, member 4
chr4_+_44012661 1.289 ENSMUST00000107849.3
ENSMUST00000107851.3
ENSMUST00000107845.3
 Clta


clathrin, light polypeptide (Lca)


chr14_-_55671873 1.283 ENSMUST00000163750.1
ENSMUST00000010520.8
 Nedd8

neural precursor cell expressed, developmentally down-regulated gene 8

chr7_-_4546567 1.249 ENSMUST00000065957.5
 Syt5
synaptotagmin V
chr5_+_29735940 1.245 ENSMUST00000114839.1
 Dnajb6
DnaJ (Hsp40) homolog, subfamily B, member 6

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 432 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.4 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 3.6 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.1 3.3 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.3 2.8 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 2.8 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.3 2.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.5 2.6 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.1 2.6 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 2.6 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 2.5 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.1 2.4 GO:0045116 protein neddylation(GO:0045116)
0.3 2.3 GO:0016093 polyprenol metabolic process(GO:0016093)
0.2 2.3 GO:0010447 response to acidic pH(GO:0010447)
0.1 2.3 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
0.7 2.1 GO:0051715 cytolysis in other organism(GO:0051715)
0.7 2.1 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.5 2.1 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.3 2.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.4 1.9 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 1.9 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 214 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 9.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 8.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 7.3 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.4 4.8 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 4.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.2 4.6 GO:0005685 U1 snRNP(GO:0005685)
0.1 3.5 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 3.2 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 3.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.2 2.7 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.5 2.6 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.3 2.6 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 2.6 GO:0000139 Golgi membrane(GO:0000139)
0.8 2.4 GO:0099631 postsynaptic endocytic zone cytoplasmic component(GO:0099631)
0.2 2.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 2.1 GO:0098984 neuron to neuron synapse(GO:0098984)
0.4 2.0 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.2 2.0 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 2.0 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
0.5 1.9 GO:1990769 proximal neuron projection(GO:1990769)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 308 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 16.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 3.5 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 3.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 3.1 GO:0031489 myosin V binding(GO:0031489)
0.0 2.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 2.7 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442)
0.2 2.4 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.4 2.3 GO:0016936 galactoside binding(GO:0016936)
0.3 2.3 GO:1990446 U1 snRNP binding(GO:1990446)
0.2 2.2 GO:0022842 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.1 2.2 GO:0043236 laminin binding(GO:0043236)
0.1 2.1 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 2.1 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.2 2.0 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 1.8 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 1.8 GO:0044390 ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 1.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 1.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 1.7 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.1 1.7 GO:0044183 protein binding involved in protein folding(GO:0044183)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.7 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 2.7 PID_ARF_3PATHWAY Arf1 pathway
0.0 2.5 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.1 1.9 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 1.9 PID_GMCSF_PATHWAY GMCSF-mediated signaling events
0.0 1.9 PID_P73PATHWAY p73 transcription factor network
0.0 1.8 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.1 1.7 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.5 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.5 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 1.3 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.1 1.2 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.1 PID_ALK1_PATHWAY ALK1 signaling events
0.1 1.0 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 1.0 ST_ADRENERGIC Adrenergic Pathway
0.0 1.0 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.0 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.0 PID_IL4_2PATHWAY IL4-mediated signaling events
0.1 0.9 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.9 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 95 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 9.5 REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.1 8.7 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.2 8.0 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 6.8 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.1 5.6 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.0 3.5 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 3.1 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 2.7 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.2 2.3 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 2.2 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 2.0 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 2.0 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.6 1.9 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 1.9 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.3 1.7 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 1.7 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 1.7 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.7 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.1 1.7 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.2 1.6 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels