Motif ID: Ep300

Z-value: 0.655


Transcription factors associated with Ep300:

Gene SymbolEntrez IDGene Name
Ep300 ENSMUSG00000055024.6 Ep300

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ep300mm10_v2_chr15_+_81586206_81586250-0.221.1e-01Click!


Activity profile for motif Ep300.

activity profile for motif Ep300


Sorted Z-values histogram for motif Ep300

Sorted Z-values for motif Ep300



Network of associatons between targets according to the STRING database.



First level regulatory network of Ep300

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_98348404 6.661 ENSMUST00000078694.6
Ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr9_-_29411736 5.318 ENSMUST00000115236.1
Ntm
neurotrimin
chr1_-_21961581 4.157 ENSMUST00000029667.6
ENSMUST00000173058.1
ENSMUST00000173404.1
Kcnq5


potassium voltage-gated channel, subfamily Q, member 5


chr19_+_23758819 3.872 ENSMUST00000025830.7
Apba1
amyloid beta (A4) precursor protein binding, family A, member 1
chr6_+_65671590 3.709 ENSMUST00000054351.4
Ndnf
neuron-derived neurotrophic factor
chr6_+_99692679 3.690 ENSMUST00000101122.1
Gpr27
G protein-coupled receptor 27
chr1_-_21961942 3.531 ENSMUST00000115300.1
Kcnq5
potassium voltage-gated channel, subfamily Q, member 5
chr18_+_51117754 3.531 ENSMUST00000116639.2
Prr16
proline rich 16
chr11_+_97415527 3.529 ENSMUST00000121799.1
Arhgap23
Rho GTPase activating protein 23
chr5_+_130448801 3.377 ENSMUST00000111288.2
Caln1
calneuron 1
chr4_+_125490688 3.355 ENSMUST00000030676.7
Grik3
glutamate receptor, ionotropic, kainate 3
chr6_-_136173492 3.308 ENSMUST00000111905.1
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr17_+_55445550 3.186 ENSMUST00000025000.3
St6gal2
beta galactoside alpha 2,6 sialyltransferase 2
chr9_-_29412204 2.919 ENSMUST00000115237.1
Ntm
neurotrimin
chr4_+_103313806 2.898 ENSMUST00000035780.3
Oma1
OMA1 homolog, zinc metallopeptidase (S. cerevisiae)
chr1_-_87573825 2.863 ENSMUST00000068681.5
Ngef
neuronal guanine nucleotide exchange factor
chr8_-_84800344 2.529 ENSMUST00000099070.3
Nfix
nuclear factor I/X
chr1_-_83408190 2.386 ENSMUST00000160953.1
Sphkap
SPHK1 interactor, AKAP domain containing
chr7_+_96522342 2.371 ENSMUST00000129737.1
Tenm4
teneurin transmembrane protein 4
chr8_-_85840877 2.242 ENSMUST00000034140.7
Itfg1
integrin alpha FG-GAP repeat containing 1
chr10_-_116473418 2.216 ENSMUST00000087965.4
ENSMUST00000164271.1
Kcnmb4

potassium large conductance calcium-activated channel, subfamily M, beta member 4

chr19_-_8723356 2.212 ENSMUST00000170157.1
Slc3a2
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr4_+_123183456 2.190 ENSMUST00000126995.1
Hpcal4
hippocalcin-like 4
chr16_-_52452465 2.153 ENSMUST00000170035.1
ENSMUST00000164728.1
Alcam

activated leukocyte cell adhesion molecule

chr8_-_70234097 2.055 ENSMUST00000130319.1
Armc6
armadillo repeat containing 6
chr19_+_44989073 1.957 ENSMUST00000026225.8
Sema4g
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr14_-_19977249 1.801 ENSMUST00000160013.1
Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr3_-_88950401 1.783 ENSMUST00000090938.4
Dap3
death associated protein 3
chr1_+_75507077 1.749 ENSMUST00000037330.4
Inha
inhibin alpha
chrX_+_159840463 1.721 ENSMUST00000112451.1
ENSMUST00000112453.2
Sh3kbp1

SH3-domain kinase binding protein 1

chr18_+_23752333 1.695 ENSMUST00000170802.1
ENSMUST00000155708.1
ENSMUST00000118826.2
Mapre2


microtubule-associated protein, RP/EB family, member 2


chr10_+_58813359 1.666 ENSMUST00000135526.2
ENSMUST00000153031.1
Sh3rf3

SH3 domain containing ring finger 3

chr8_+_112570043 1.647 ENSMUST00000034225.6
ENSMUST00000118171.1
Cntnap4

contactin associated protein-like 4

chrX_+_85574018 1.588 ENSMUST00000048250.3
ENSMUST00000137438.1
ENSMUST00000146063.1
Tab3


TGF-beta activated kinase 1/MAP3K7 binding protein 3


chr2_+_30392405 1.585 ENSMUST00000113612.3
ENSMUST00000123202.1
Dolpp1

dolichyl pyrophosphate phosphatase 1

chr8_+_39005880 1.580 ENSMUST00000169034.1
Tusc3
tumor suppressor candidate 3
chr8_+_39005827 1.571 ENSMUST00000167992.1
Tusc3
tumor suppressor candidate 3
chr10_-_116473875 1.565 ENSMUST00000068233.4
Kcnmb4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr14_+_70457447 1.531 ENSMUST00000003561.3
Phyhip
phytanoyl-CoA hydroxylase interacting protein
chr16_-_13986855 1.522 ENSMUST00000117803.1
Ifitm7
interferon induced transmembrane protein 7
chr1_-_183297008 1.494 ENSMUST00000057062.5
Brox
BRO1 domain and CAAX motif containing
chr14_-_19977151 1.481 ENSMUST00000055100.7
ENSMUST00000162425.1
Gng2

guanine nucleotide binding protein (G protein), gamma 2

chr10_-_57532416 1.480 ENSMUST00000169122.1
Serinc1
serine incorporator 1
chr14_-_19977040 1.463 ENSMUST00000159028.1
Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr16_-_52452654 1.458 ENSMUST00000168071.1
Alcam
activated leukocyte cell adhesion molecule
chr14_-_70159433 1.399 ENSMUST00000058240.7
ENSMUST00000153871.1
9930012K11Rik

RIKEN cDNA 9930012K11 gene

chr13_-_54749627 1.394 ENSMUST00000099506.1
Gprin1
G protein-regulated inducer of neurite outgrowth 1
chr4_-_148038769 1.379 ENSMUST00000030879.5
ENSMUST00000137724.1
Clcn6

chloride channel 6

chr4_-_123527648 1.370 ENSMUST00000147228.1
Macf1
microtubule-actin crosslinking factor 1
chr2_+_163602331 1.358 ENSMUST00000152135.1
Ttpal
tocopherol (alpha) transfer protein-like
chr8_-_11550689 1.339 ENSMUST00000049461.5
Cars2
cysteinyl-tRNA synthetase 2 (mitochondrial)(putative)
chr2_+_91650169 1.339 ENSMUST00000090614.4
Arhgap1
Rho GTPase activating protein 1
chr15_-_79505241 1.331 ENSMUST00000057801.6
Kcnj4
potassium inwardly-rectifying channel, subfamily J, member 4
chr6_-_113531575 1.315 ENSMUST00000032425.5
Emc3
ER membrane protein complex subunit 3
chr17_+_37050631 1.312 ENSMUST00000172792.1
ENSMUST00000174347.1
Gabbr1

gamma-aminobutyric acid (GABA) B receptor, 1

chr10_+_79916957 1.304 ENSMUST00000045529.2
Kiss1r
KISS1 receptor
chr2_+_91650116 1.302 ENSMUST00000111331.2
Arhgap1
Rho GTPase activating protein 1
chr10_-_63244135 1.274 ENSMUST00000054837.3
1700120B22Rik
RIKEN cDNA 1700120B22 gene
chr9_+_40192308 1.270 ENSMUST00000026693.7
ENSMUST00000168832.1
Zfp202

zinc finger protein 202

chr4_-_41870612 1.216 ENSMUST00000179680.1
Gm21966
predicted gene, 21966
chr18_-_24603464 1.212 ENSMUST00000154205.1
Slc39a6
solute carrier family 39 (metal ion transporter), member 6
chr3_-_146812951 1.212 ENSMUST00000102515.3
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr18_+_24603952 1.211 ENSMUST00000025120.6
Elp2
elongator acetyltransferase complex subunit 2
chr6_-_29216301 1.159 ENSMUST00000162739.1
ENSMUST00000162099.1
ENSMUST00000159124.1
Impdh1


inosine 5'-phosphate dehydrogenase 1


chr16_-_94526830 1.152 ENSMUST00000023615.6
Dscr3
Down syndrome critical region gene 3
chr8_+_93810832 1.145 ENSMUST00000034198.8
ENSMUST00000125716.1
Gnao1

guanine nucleotide binding protein, alpha O

chr19_+_47178820 1.139 ENSMUST00000111808.3
Neurl1a
neuralized homolog 1A (Drosophila)
chr5_-_25100624 1.139 ENSMUST00000030784.7
Prkag2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr13_-_54749849 1.136 ENSMUST00000135343.1
Gprin1
G protein-regulated inducer of neurite outgrowth 1
chr10_-_67548944 1.135 ENSMUST00000075686.4
Ado
2-aminoethanethiol (cysteamine) dioxygenase
chr12_+_86241848 1.129 ENSMUST00000071106.4
Gpatch2l
G patch domain containing 2 like
chr8_+_104101625 1.121 ENSMUST00000034339.8
Cdh5
cadherin 5
chr1_-_168431695 1.114 ENSMUST00000176790.1
Pbx1
pre B cell leukemia homeobox 1
chr10_-_57532489 1.099 ENSMUST00000020027.4
Serinc1
serine incorporator 1
chr17_-_24644933 1.072 ENSMUST00000019684.5
Slc9a3r2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr2_+_91082362 1.015 ENSMUST00000169852.1
Spi1
spleen focus forming virus (SFFV) proviral integration oncogene
chr2_+_180456234 1.011 ENSMUST00000038259.6
Slco4a1
solute carrier organic anion transporter family, member 4a1
chr2_+_57238297 1.007 ENSMUST00000112618.2
ENSMUST00000028167.2
Gpd2

glycerol phosphate dehydrogenase 2, mitochondrial

chr1_-_91459254 1.004 ENSMUST00000069620.8
Per2
period circadian clock 2
chr13_+_73604002 0.999 ENSMUST00000022102.7
Clptm1l
CLPTM1-like
chr15_+_6386598 0.969 ENSMUST00000080880.5
ENSMUST00000110664.2
ENSMUST00000110663.2
ENSMUST00000161812.1
ENSMUST00000160134.1
Dab2




disabled 2, mitogen-responsive phosphoprotein




chr2_+_25054355 0.966 ENSMUST00000100334.4
ENSMUST00000152122.1
ENSMUST00000116574.3
ENSMUST00000006646.8
Nsmf



NMDA receptor synaptonuclear signaling and neuronal migration factor



chr2_-_102400257 0.961 ENSMUST00000152929.1
Trim44
tripartite motif-containing 44
chr12_+_78226627 0.948 ENSMUST00000110388.2
ENSMUST00000052472.4
Gphn

gephyrin

chr18_-_24603791 0.927 ENSMUST00000070726.3
Slc39a6
solute carrier family 39 (metal ion transporter), member 6
chr17_+_35841668 0.922 ENSMUST00000174124.1
Mdc1
mediator of DNA damage checkpoint 1
chr15_+_74516196 0.921 ENSMUST00000042035.9
Bai1
brain-specific angiogenesis inhibitor 1
chr11_-_97744659 0.895 ENSMUST00000018691.8
Pip4k2b
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chr8_-_105966038 0.859 ENSMUST00000116429.2
ENSMUST00000034370.9
Slc12a4

solute carrier family 12, member 4

chr7_-_132317198 0.857 ENSMUST00000080215.5
Chst15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr2_+_25054396 0.845 ENSMUST00000102931.4
ENSMUST00000074422.7
ENSMUST00000132172.1
ENSMUST00000114388.1
ENSMUST00000114386.1
Nsmf




NMDA receptor synaptonuclear signaling and neuronal migration factor




chr7_-_109752210 0.831 ENSMUST00000128043.1
ENSMUST00000033333.6
Tmem9b

TMEM9 domain family, member B

chr2_-_57124003 0.825 ENSMUST00000112629.1
Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr11_-_116307168 0.818 ENSMUST00000124281.1
Exoc7
exocyst complex component 7
chr8_-_70608261 0.814 ENSMUST00000049908.9
Ssbp4
single stranded DNA binding protein 4
chr12_+_84009481 0.808 ENSMUST00000168120.1
Acot1
acyl-CoA thioesterase 1
chr2_+_163602294 0.803 ENSMUST00000171696.1
ENSMUST00000109408.3
Ttpal

tocopherol (alpha) transfer protein-like

chr16_-_9994921 0.803 ENSMUST00000115835.1
Grin2a
glutamate receptor, ionotropic, NMDA2A (epsilon 1)
chr11_+_70764209 0.788 ENSMUST00000060444.5
Zfp3
zinc finger protein 3
chr9_+_75037712 0.784 ENSMUST00000007800.7
Arpp19
cAMP-regulated phosphoprotein 19
chr6_-_97617536 0.756 ENSMUST00000113355.2
Frmd4b
FERM domain containing 4B
chr11_-_116306652 0.751 ENSMUST00000126731.1
Exoc7
exocyst complex component 7
chr2_-_31845925 0.748 ENSMUST00000028188.7
Fibcd1
fibrinogen C domain containing 1
chr8_-_121829480 0.745 ENSMUST00000174717.1
ENSMUST00000174192.1
ENSMUST00000045884.10
Klhdc4


kelch domain containing 4


chr11_+_49244191 0.733 ENSMUST00000167400.1
ENSMUST00000081794.6
Mgat1

mannoside acetylglucosaminyltransferase 1

chr11_-_116306696 0.729 ENSMUST00000133468.1
ENSMUST00000106411.3
ENSMUST00000106413.3
ENSMUST00000021147.7
Exoc7



exocyst complex component 7



chr9_-_20952838 0.724 ENSMUST00000004202.9
Dnmt1
DNA methyltransferase (cytosine-5) 1
chr8_+_70234187 0.723 ENSMUST00000164403.1
ENSMUST00000093458.4
Sugp2

SURP and G patch domain containing 2

chr13_-_100730839 0.716 ENSMUST00000091299.6
Cdk7
cyclin-dependent kinase 7
chr2_+_153741274 0.703 ENSMUST00000028981.8
Mapre1
microtubule-associated protein, RP/EB family, member 1
chr10_-_79916912 0.699 ENSMUST00000045628.7
ENSMUST00000171416.1
R3hdm4

R3H domain containing 4

chr7_-_127876777 0.684 ENSMUST00000106262.1
ENSMUST00000106263.1
ENSMUST00000054415.5
Zfp668


zinc finger protein 668


chr4_+_149485215 0.662 ENSMUST00000124413.1
ENSMUST00000141293.1
Lzic

leucine zipper and CTNNBIP1 domain containing

chr2_-_155514796 0.643 ENSMUST00000029131.4
Ggt7
gamma-glutamyltransferase 7
chr19_+_8735808 0.642 ENSMUST00000049424.9
Wdr74
WD repeat domain 74
chr8_+_106150359 0.633 ENSMUST00000034377.6
Pla2g15
phospholipase A2, group XV
chr1_-_177258182 0.620 ENSMUST00000111159.1
Akt3
thymoma viral proto-oncogene 3
chr6_+_86438666 0.605 ENSMUST00000113700.1
C87436
expressed sequence C87436
chr12_+_113014502 0.604 ENSMUST00000084891.4
Pacs2
phosphofurin acidic cluster sorting protein 2
chr2_+_172440556 0.599 ENSMUST00000029005.3
Rtfdc1
replication termination factor 2 domain containing 1
chr2_-_152831665 0.598 ENSMUST00000156688.1
ENSMUST00000007803.5
Bcl2l1

BCL2-like 1

chr6_+_86438360 0.583 ENSMUST00000050497.7
C87436
expressed sequence C87436
chr5_+_122391878 0.580 ENSMUST00000102525.4
Arpc3
actin related protein 2/3 complex, subunit 3
chr17_+_78200240 0.573 ENSMUST00000112498.2
Crim1
cysteine rich transmembrane BMP regulator 1 (chordin like)
chr2_-_27426992 0.571 ENSMUST00000056176.7
Vav2
vav 2 oncogene
chr4_+_149485260 0.550 ENSMUST00000030842.7
Lzic
leucine zipper and CTNNBIP1 domain containing
chr10_+_59221945 0.542 ENSMUST00000182161.1
Sowahc
sosondowah ankyrin repeat domain family member C
chr14_+_54426902 0.534 ENSMUST00000010550.7
Mrpl52
mitochondrial ribosomal protein L52
chr4_+_129136948 0.522 ENSMUST00000102600.3
Fndc5
fibronectin type III domain containing 5
chr16_+_18248866 0.521 ENSMUST00000115640.1
ENSMUST00000140206.1
Trmt2a

TRM2 tRNA methyltransferase 2A

chr8_+_72219726 0.520 ENSMUST00000003123.8
Fam32a
family with sequence similarity 32, member A
chr7_+_44428938 0.512 ENSMUST00000127790.1
Lrrc4b
leucine rich repeat containing 4B
chr6_+_55037988 0.511 ENSMUST00000003572.8
Gars
glycyl-tRNA synthetase
chr7_-_79920599 0.505 ENSMUST00000075657.6
Ap3s2
adaptor-related protein complex 3, sigma 2 subunit
chr1_-_184732616 0.499 ENSMUST00000048572.6
Hlx
H2.0-like homeobox
chr19_-_46338632 0.497 ENSMUST00000051234.8
ENSMUST00000167861.1
Cuedc2

CUE domain containing 2

chr14_-_121379206 0.495 ENSMUST00000079817.7
Stk24
serine/threonine kinase 24
chr7_+_127876796 0.494 ENSMUST00000131000.1
Zfp646
zinc finger protein 646
chr3_-_90433603 0.490 ENSMUST00000029542.5
ENSMUST00000071488.3
Ints3

integrator complex subunit 3

chr4_-_116555896 0.485 ENSMUST00000069674.5
ENSMUST00000106478.2
Tmem69

transmembrane protein 69

chr7_-_140882274 0.480 ENSMUST00000026559.7
Sirt3
sirtuin 3
chr2_-_152831112 0.479 ENSMUST00000128172.1
Bcl2l1
BCL2-like 1
chr4_+_86575668 0.479 ENSMUST00000091064.6
Rraga
Ras-related GTP binding A
chr11_+_4986824 0.478 ENSMUST00000009234.9
ENSMUST00000109897.1
Ap1b1

adaptor protein complex AP-1, beta 1 subunit

chr3_-_63964659 0.466 ENSMUST00000161659.1
Slc33a1
solute carrier family 33 (acetyl-CoA transporter), member 1
chrX_+_36112110 0.460 ENSMUST00000033418.7
Il13ra1
interleukin 13 receptor, alpha 1
chr1_-_34843050 0.458 ENSMUST00000170092.1
ENSMUST00000167518.1
ENSMUST00000047534.5
Fam168b


family with sequence similarity 168, member B


chr3_-_108085346 0.447 ENSMUST00000078912.5
Ampd2
adenosine monophosphate deaminase 2
chr11_-_40755201 0.431 ENSMUST00000020576.7
Ccng1
cyclin G1
chr12_-_80260356 0.430 ENSMUST00000021554.8
Actn1
actinin, alpha 1
chr11_+_114851142 0.425 ENSMUST00000133245.1
ENSMUST00000122967.2
Gprc5c

G protein-coupled receptor, family C, group 5, member C

chr3_-_88951090 0.418 ENSMUST00000173021.1
Dap3
death associated protein 3
chr9_+_75037614 0.418 ENSMUST00000168166.1
ENSMUST00000169492.1
ENSMUST00000170308.1
Arpp19


cAMP-regulated phosphoprotein 19


chr18_-_73754457 0.412 ENSMUST00000041138.2
Elac1
elaC homolog 1 (E. coli)
chr6_+_86438714 0.391 ENSMUST00000113698.1
C87436
expressed sequence C87436
chr15_+_102102926 0.391 ENSMUST00000169627.1
ENSMUST00000046144.9
Tenc1

tensin like C1 domain-containing phosphatase

chr19_-_41981119 0.386 ENSMUST00000026168.2
ENSMUST00000171561.1
Mms19

MMS19 (MET18 S. cerevisiae)

chr16_+_18248961 0.385 ENSMUST00000100099.3
Trmt2a
TRM2 tRNA methyltransferase 2A
chr6_-_83506895 0.363 ENSMUST00000113888.1
ENSMUST00000014698.3
Dguok

deoxyguanosine kinase

chrX_-_107816238 0.356 ENSMUST00000120722.1
2610002M06Rik
RIKEN cDNA 2610002M06 gene
chr12_-_112673944 0.353 ENSMUST00000130342.1
Akt1
thymoma viral proto-oncogene 1
chr3_-_27710413 0.347 ENSMUST00000046157.4
Fndc3b
fibronectin type III domain containing 3B
chr18_+_32067729 0.342 ENSMUST00000025243.3
Iws1
IWS1 homolog (S. cerevisiae)
chr19_-_7105729 0.331 ENSMUST00000113383.2
Flrt1
fibronectin leucine rich transmembrane protein 1
chr7_+_45155865 0.320 ENSMUST00000107811.1
Pih1d1
PIH1 domain containing 1
chr11_+_6546899 0.315 ENSMUST00000159007.1
Ccm2
cerebral cavernous malformation 2
chr15_-_13173607 0.310 ENSMUST00000036439.4
Cdh6
cadherin 6
chr2_-_26021679 0.308 ENSMUST00000036509.7
Ubac1
ubiquitin associated domain containing 1
chr9_+_75037744 0.297 ENSMUST00000168301.1
Arpp19
cAMP-regulated phosphoprotein 19
chr17_+_35841491 0.291 ENSMUST00000082337.6
Mdc1
mediator of DNA damage checkpoint 1
chr13_-_58128542 0.289 ENSMUST00000007980.6
Hnrnpa0
heterogeneous nuclear ribonucleoprotein A0
chr3_-_88950271 0.287 ENSMUST00000174402.1
ENSMUST00000174077.1
Dap3

death associated protein 3

chr9_+_22003035 0.286 ENSMUST00000115331.2
ENSMUST00000003493.7
Prkcsh

protein kinase C substrate 80K-H

chr11_+_6546875 0.280 ENSMUST00000000388.8
Ccm2
cerebral cavernous malformation 2
chr10_-_80102653 0.275 ENSMUST00000042771.7
Sbno2
strawberry notch homolog 2 (Drosophila)
chr2_+_154656959 0.259 ENSMUST00000044277.9
Chmp4b
charged multivesicular body protein 4B
chr13_-_55362782 0.249 ENSMUST00000021940.7
Lman2
lectin, mannose-binding 2
chr4_-_118409219 0.245 ENSMUST00000075406.5
Szt2
seizure threshold 2
chr18_+_31804057 0.243 ENSMUST00000025264.6
ENSMUST00000082319.7
Wdr33

WD repeat domain 33

chr5_+_34336289 0.237 ENSMUST00000182709.1
ENSMUST00000030992.6
Rnf4

ring finger protein 4

chr1_+_121431049 0.234 ENSMUST00000036025.9
ENSMUST00000112621.1
Ccdc93

coiled-coil domain containing 93

chr2_-_52676571 0.233 ENSMUST00000178799.1
Cacnb4
calcium channel, voltage-dependent, beta 4 subunit
chr2_-_26021532 0.232 ENSMUST00000136750.1
Ubac1
ubiquitin associated domain containing 1
chr6_+_142345648 0.227 ENSMUST00000041852.7
Pyroxd1
pyridine nucleotide-disulphide oxidoreductase domain 1
chr11_-_93968293 0.219 ENSMUST00000170303.1
Gm20390
predicted gene 20390
chr5_+_30814722 0.218 ENSMUST00000114724.1
Mapre3
microtubule-associated protein, RP/EB family, member 3
chr19_+_8723478 0.214 ENSMUST00000180819.1
ENSMUST00000181422.1
Snhg1

small nucleolar RNA host gene (non-protein coding) 1

chr8_+_11556061 0.204 ENSMUST00000054399.4
Ing1
inhibitor of growth family, member 1
chr1_-_92641942 0.189 ENSMUST00000097642.3
Myeov2
myeloma overexpressed 2
chr7_+_140882430 0.180 ENSMUST00000164681.1
ENSMUST00000163610.1
Psmd13

proteasome (prosome, macropain) 26S subunit, non-ATPase, 13

chr5_-_90366176 0.175 ENSMUST00000014421.8
ENSMUST00000081914.6
ENSMUST00000168058.2
Ankrd17


ankyrin repeat domain 17


chr11_-_120990871 0.175 ENSMUST00000154483.1
Csnk1d
casein kinase 1, delta
chr9_+_75037809 0.173 ENSMUST00000167885.1
Arpp19
cAMP-regulated phosphoprotein 19
chr7_+_48789003 0.171 ENSMUST00000118927.1
ENSMUST00000125280.1
Zdhhc13

zinc finger, DHHC domain containing 13

chr10_-_30655859 0.170 ENSMUST00000092610.4
Ncoa7
nuclear receptor coactivator 7
chr11_-_93968242 0.168 ENSMUST00000107844.2
Nme1
NME/NM23 nucleoside diphosphate kinase 1
chr10_-_127211528 0.164 ENSMUST00000013970.7
Pip4k2c
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr1_+_119526125 0.163 ENSMUST00000183952.1
TMEM185B
Transmembrane protein 185B
chr9_+_75037838 0.163 ENSMUST00000169188.1
Arpp19
cAMP-regulated phosphoprotein 19
chr11_-_120581196 0.160 ENSMUST00000067936.5
Arhgdia
Rho GDP dissociation inhibitor (GDI) alpha

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.7 GO:0007621 negative regulation of female receptivity(GO:0007621)
1.2 3.7 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.8 3.3 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.6 2.4 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.6 2.9 GO:0010637 diet induced thermogenesis(GO:0002024) negative regulation of mitochondrial fusion(GO:0010637)
0.5 2.6 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.5 3.8 GO:0005513 detection of calcium ion(GO:0005513)
0.5 1.8 GO:0099527 postsynapse to nucleus signaling pathway(GO:0099527)
0.4 2.2 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.4 3.7 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) vascular wound healing(GO:0061042)
0.4 2.6 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.3 1.0 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
0.3 3.4 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.3 1.7 GO:0046880 regulation of follicle-stimulating hormone secretion(GO:0046880) follicle-stimulating hormone secretion(GO:0046884)
0.3 2.9 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.3 5.4 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.3 1.1 GO:0046898 response to cycloheximide(GO:0046898)
0.2 1.2 GO:0006177 GMP biosynthetic process(GO:0006177)
0.2 0.9 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.2 0.8 GO:0051866 general adaptation syndrome(GO:0051866)
0.2 1.0 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.2 1.0 GO:0070327 thyroid hormone transport(GO:0070327)
0.2 2.1 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.2 0.9 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.2 1.3 GO:0001955 blood vessel maturation(GO:0001955)
0.2 0.7 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.2 0.7 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.2 4.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.2 3.2 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.2 2.3 GO:0035635 entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.2 3.2 GO:0015693 magnesium ion transport(GO:0015693)
0.2 1.0 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.2 1.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.2 1.6 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.2 1.1 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.2 1.0 GO:0032346 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349) leading edge cell differentiation(GO:0035026) regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.2 0.6 GO:0006751 glutathione catabolic process(GO:0006751)
0.2 0.5 GO:0035963 response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.1 1.6 GO:2000821 regulation of grooming behavior(GO:2000821)
0.1 2.5 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.8 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 0.5 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.1 0.4 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.1 1.2 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.1 1.1 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.1 0.5 GO:0015960 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.1 0.6 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 3.6 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 0.4 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.1 2.4 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 1.3 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.1 0.3 GO:1900110 negative regulation of histone H3-K9 dimethylation(GO:1900110)
0.1 0.5 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.1 0.3 GO:0071105 response to interleukin-11(GO:0071105)
0.1 1.8 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 0.5 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.1 0.4 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.1 0.6 GO:1902969 mitotic DNA replication(GO:1902969)
0.1 0.2 GO:0060709 glycogen cell differentiation involved in embryonic placenta development(GO:0060709)
0.1 0.4 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.1 0.6 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.1 0.5 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.1 8.6 GO:0071805 potassium ion transmembrane transport(GO:0071805)
0.0 0.2 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.3 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 8.2 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.0 2.0 GO:0050919 negative chemotaxis(GO:0050919)
0.0 1.1 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 1.1 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.1 GO:0035771 interleukin-4-mediated signaling pathway(GO:0035771)
0.0 0.6 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.1 GO:1904154 trimming of terminal mannose on B branch(GO:0036509) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0 0.5 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.0 0.2 GO:0085020 cellular response to testosterone stimulus(GO:0071394) protein K6-linked ubiquitination(GO:0085020)
0.0 0.6 GO:0051639 actin filament network formation(GO:0051639)
0.0 1.4 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 1.1 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.2 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.3 GO:0060510 Type II pneumocyte differentiation(GO:0060510)
0.0 1.1 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 1.3 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.9 GO:0006813 potassium ion transport(GO:0006813)
0.0 0.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.5 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.5 GO:0016180 snRNA processing(GO:0016180)
0.0 0.8 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.4 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.2 GO:0006183 GTP biosynthetic process(GO:0006183)
0.0 0.9 GO:0019319 hexose biosynthetic process(GO:0019319)
0.0 0.3 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 1.3 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 1.9 GO:1904892 regulation of JAK-STAT cascade(GO:0046425) regulation of STAT cascade(GO:1904892)
0.0 0.6 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.3 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.0 GO:0002946 tRNA C5-cytosine methylation(GO:0002946)
0.0 0.8 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.0 2.0 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.6 GO:1900046 regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0043512 inhibin-betaglycan-ActRII complex(GO:0034673) inhibin A complex(GO:0043512)
0.4 2.6 GO:0097443 sorting endosome(GO:0097443)
0.3 1.3 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.2 1.0 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2 4.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.2 0.7 GO:0070985 TFIIK complex(GO:0070985)
0.2 3.6 GO:0042101 T cell receptor complex(GO:0042101)
0.2 3.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.2 2.3 GO:0032584 growth cone membrane(GO:0032584)
0.2 1.0 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2 0.7 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.2 1.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.2 2.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.7 GO:1990130 Iml1 complex(GO:1990130)
0.1 0.6 GO:0032127 dense core granule membrane(GO:0032127)
0.1 6.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 8.2 GO:0030118 clathrin coat(GO:0030118)
0.1 3.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 1.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 1.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.5 GO:0070876 SOSS complex(GO:0070876)
0.1 3.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 1.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 1.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 2.5 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 0.5 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.1 2.5 GO:0097440 apical dendrite(GO:0097440)
0.1 8.1 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.9 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.3 GO:0097255 R2TP complex(GO:0097255)
0.0 3.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.9 GO:0060077 inhibitory synapse(GO:0060077)
0.0 1.1 GO:0032420 stereocilium(GO:0032420)
0.0 0.7 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 3.1 GO:0008021 synaptic vesicle(GO:0008021)
0.0 2.2 GO:0030018 Z disc(GO:0030018)
0.0 0.3 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 1.1 GO:0005776 autophagosome(GO:0005776)
0.0 0.1 GO:0097361 CIA complex(GO:0097361)
0.0 1.5 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 3.9 GO:0000139 Golgi membrane(GO:0000139)
0.0 1.4 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 2.0 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 6.9 GO:0043025 neuronal cell body(GO:0043025)
0.0 3.3 GO:0005578 proteinaceous extracellular matrix(GO:0005578)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.7 GO:0031752 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
1.1 1.1 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.7 3.4 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.6 3.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.4 3.3 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.4 1.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.3 1.0 GO:0016901 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.3 4.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.3 1.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.3 0.9 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.3 1.0 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.2 3.2 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.2 0.9 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.2 3.8 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.2 1.3 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.2 0.7 GO:0008061 chitin binding(GO:0008061)
0.2 2.6 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.2 0.7 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.2 1.6 GO:0034711 inhibin binding(GO:0034711)
0.2 1.0 GO:0051525 NFAT protein binding(GO:0051525)
0.2 1.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 0.8 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 0.9 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 1.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 1.1 GO:0051434 BH3 domain binding(GO:0051434)
0.1 9.0 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.1 1.3 GO:0042923 neuropeptide binding(GO:0042923)
0.1 1.1 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 0.6 GO:0008242 omega peptidase activity(GO:0008242)
0.1 0.4 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 0.7 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 1.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 1.0 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 2.2 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 0.4 GO:0051185 coenzyme transporter activity(GO:0051185)
0.1 0.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.6 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 1.0 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 3.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 2.3 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 2.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.8 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 2.4 GO:0051018 protein kinase A binding(GO:0051018)
0.0 1.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.1 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 1.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.2 GO:0033142 progesterone receptor binding(GO:0033142)
0.0 1.8 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 2.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.6 GO:0017166 vinculin binding(GO:0017166)
0.0 0.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 3.7 GO:0008201 heparin binding(GO:0008201)
0.0 0.5 GO:0070403 NAD+ binding(GO:0070403)
0.0 4.4 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.1 GO:0045182 translation regulator activity(GO:0045182)
0.0 0.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 1.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.8 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 2.3 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.3 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.6 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 2.0 GO:0008565 protein transporter activity(GO:0008565)
0.0 2.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.6 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.4 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.9 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 0.2 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 3.0 GO:0008017 microtubule binding(GO:0008017)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 3.0 GO:0005096 GTPase activator activity(GO:0005096)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.5 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.1 6.6 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.1 1.2 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.1 0.5 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.1 1.1 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.1 1.2 PID_ATM_PATHWAY ATM pathway
0.1 2.3 PID_IL3_PATHWAY IL3-mediated signaling events
0.1 4.3 PID_REELIN_PATHWAY Reelin signaling pathway
0.1 2.5 PID_TRAIL_PATHWAY TRAIL signaling pathway
0.1 1.0 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 0.7 ST_INTERLEUKIN_4_PATHWAY Interleukin 4 (IL-4) Pathway
0.0 2.2 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.7 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 2.9 PID_CDC42_PATHWAY CDC42 signaling events
0.0 0.7 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 4.3 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.1 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.0 0.2 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.8 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 0.6 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.0 0.7 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 0.6 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.1 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.5 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 2.0 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.2 7.9 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.2 4.1 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.2 3.4 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 7.7 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.2 7.5 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.2 3.8 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.1 1.0 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.1 2.1 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.1 1.1 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.1 1.6 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 1.1 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 1.8 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 1.2 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.1 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.1 0.7 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 2.2 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.1 1.2 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 0.9 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.1 4.4 REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.1 1.0 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.1 1.7 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.8 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.9 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.7 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 1.4 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 3.0 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 3.6 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions
0.0 0.5 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.6 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.9 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.6 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 1.0 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.8 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME_CIRCADIAN_CLOCK Genes involved in Circadian Clock
0.0 0.3 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.4 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules