Motif ID: Esrrg

Z-value: 0.404


Transcription factors associated with Esrrg:

Gene SymbolEntrez IDGene Name
Esrrg ENSMUSG00000026610.7 Esrrg

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Esrrgmm10_v2_chr1_+_187609028_1876090470.274.6e-02Click!


Activity profile for motif Esrrg.

activity profile for motif Esrrg


Sorted Z-values histogram for motif Esrrg

Sorted Z-values for motif Esrrg



Network of associatons between targets according to the STRING database.



First level regulatory network of Esrrg

PNG image of the network

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Top targets:


Showing 1 to 20 of 159 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_68869563 3.634 ENSMUST00000054551.2
 1110032F04Rik
RIKEN cDNA 1110032F04 gene
chr9_-_107668967 3.137 ENSMUST00000177567.1
 Slc38a3
solute carrier family 38, member 3
chr8_-_46294592 2.436 ENSMUST00000058636.7
 Helt
helt bHLH transcription factor
chr18_+_77185815 2.367 ENSMUST00000079618.4
 St8sia5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr18_+_57142782 2.267 ENSMUST00000139892.1
 Megf10
multiple EGF-like-domains 10
chr9_-_54661666 1.601 ENSMUST00000128624.1
 Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr14_+_20929416 1.594 ENSMUST00000022369.7
 Vcl
vinculin
chr15_+_25742314 1.580 ENSMUST00000135981.1
 Myo10
myosin X
chr7_-_116237767 1.578 ENSMUST00000182834.1
 Plekha7
pleckstrin homology domain containing, family A member 7
chr1_+_104768510 1.543 ENSMUST00000062528.8
 Cdh20
cadherin 20
chr13_-_51567084 1.490 ENSMUST00000021898.5
 Shc3
src homology 2 domain-containing transforming protein C3
chr9_-_54647199 1.288 ENSMUST00000128163.1
 Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr7_-_93081027 1.264 ENSMUST00000098303.1
 Gm9934
predicted gene 9934
chr3_+_90514435 1.248 ENSMUST00000048138.6
ENSMUST00000181271.1
 S100a13

S100 calcium binding protein A13

chr7_-_105482197 1.230 ENSMUST00000047040.2
 Prkcdbp
protein kinase C, delta binding protein
chr7_-_37772868 1.127 ENSMUST00000176205.1
 Zfp536
zinc finger protein 536
chr2_+_131186942 1.068 ENSMUST00000028804.8
ENSMUST00000079857.8
 Cdc25b

cell division cycle 25B

chr3_-_90514250 0.956 ENSMUST00000107340.1
ENSMUST00000060738.8
 S100a1

S100 calcium binding protein A1

chr1_-_5070281 0.930 ENSMUST00000147158.1
ENSMUST00000118000.1
 Rgs20

regulator of G-protein signaling 20

chr14_+_78849171 0.755 ENSMUST00000040990.5
 Vwa8
von Willebrand factor A domain containing 8

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 60 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 3.1 GO:0015817 glutamine transport(GO:0006868) histidine transport(GO:0015817) cellular response to potassium ion starvation(GO:0051365)
0.1 2.9 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 2.6 GO:0043413 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.1 2.4 GO:0097154 GABAergic neuron differentiation(GO:0097154)
0.4 2.3 GO:0043654 skeletal muscle satellite cell activation(GO:0014719) recognition of apoptotic cell(GO:0043654)
0.1 1.7 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.3 1.6 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 1.6 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 1.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.5 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 1.4 GO:0071277 cellular response to calcium ion(GO:0071277)
0.4 1.2 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.2 1.1 GO:0007144 female meiosis I(GO:0007144)
0.0 1.1 GO:0031065 positive regulation of histone deacetylation(GO:0031065)
0.0 1.1 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 1.0 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.1 0.8 GO:0016576 histone dephosphorylation(GO:0016576)
0.2 0.7 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 0.7 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.7 GO:1900027 regulation of ruffle assembly(GO:1900027)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.7 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 2.3 GO:0001891 phagocytic cup(GO:0001891)
0.1 1.6 GO:0005915 zonula adherens(GO:0005915)
0.0 1.6 GO:0016459 myosin complex(GO:0016459)
0.1 1.3 GO:0005916 fascia adherens(GO:0005916)
0.0 1.0 GO:0031430 M band(GO:0031430)
0.0 0.8 GO:1990635 proximal dendrite(GO:1990635)
0.2 0.7 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 0.6 GO:0071439 clathrin complex(GO:0071439)
0.1 0.5 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 0.4 GO:0098855 HCN channel complex(GO:0098855)
0.1 0.4 GO:0097452 GAIT complex(GO:0097452)
0.0 0.4 GO:0046930 pore complex(GO:0046930)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.0 0.2 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.1 GO:0005745 m-AAA complex(GO:0005745)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
1.0 3.1 GO:0015182 L-asparagine transmembrane transporter activity(GO:0015182)
0.5 2.9 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.3 2.9 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.3 2.3 GO:0001849 complement component C1q binding(GO:0001849)
0.1 1.7 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 1.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 1.6 GO:0070097 delta-catenin binding(GO:0070097)
0.0 1.3 GO:0030507 spectrin binding(GO:0030507)
0.2 1.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 1.0 GO:0044548 S100 protein binding(GO:0044548)
0.0 1.0 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.8 GO:0051879 Hsp90 protein binding(GO:0051879)
0.2 0.7 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.2 0.7 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.7 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.7 GO:0030332 cyclin binding(GO:0030332)
0.1 0.6 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 0.5 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)

Gene overrepresentation in C2:CP category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.2 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 3.2 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 1.8 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.6 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 1.4 PID_RAS_PATHWAY Regulation of Ras family activation
0.1 1.1 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.9 ST_G_ALPHA_I_PATHWAY G alpha i Pathway
0.0 0.8 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 0.7 PID_BARD1_PATHWAY BARD1 signaling events
0.0 0.5 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.5 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.0 0.2 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.1 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.6 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.4 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.4 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.1 1.1 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 1.0 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 0.9 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.0 0.9 REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS Genes involved in G alpha (z) signalling events
0.1 0.7 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.7 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.6 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.5 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.4 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME_P38MAPK_EVENTS Genes involved in p38MAPK events
0.0 0.3 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.3 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 0.2 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.2 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.1 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection