Motif ID: Ezh2_Atf2_Ikzf1

Z-value: 1.690

Transcription factors associated with Ezh2_Atf2_Ikzf1:

Gene SymbolEntrez IDGene Name
Atf2 ENSMUSG00000027104.12 Atf2
Ezh2 ENSMUSG00000029687.10 Ezh2
Ikzf1 ENSMUSG00000018654.11 Ikzf1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Atf2mm10_v2_chr2_-_73892588_738926160.776.9e-12Click!
Ezh2mm10_v2_chr6_-_47594967_475950470.201.5e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Ezh2_Atf2_Ikzf1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_34745952 16.502 ENSMUST00000123823.1
ENSMUST00000136907.1
ENSMUST00000126181.1
Cald1


caldesmon 1


chr1_-_190170671 16.336 ENSMUST00000175916.1
Prox1
prospero-related homeobox 1
chr6_+_34746368 13.006 ENSMUST00000142716.1
Cald1
caldesmon 1
chr9_-_117252450 12.491 ENSMUST00000111773.3
ENSMUST00000068962.7
ENSMUST00000044901.7
Rbms3


RNA binding motif, single stranded interacting protein


chr2_+_152081529 12.154 ENSMUST00000064061.3
Scrt2
scratch homolog 2, zinc finger protein (Drosophila)
chr1_-_190170178 11.186 ENSMUST00000177288.1
Prox1
prospero-related homeobox 1
chr6_+_141524379 10.678 ENSMUST00000032362.9
Slco1c1
solute carrier organic anion transporter family, member 1c1
chr2_+_4300462 9.616 ENSMUST00000175669.1
Frmd4a
FERM domain containing 4A
chr4_-_82505707 8.333 ENSMUST00000107248.1
ENSMUST00000107247.1
Nfib

nuclear factor I/B

chr14_+_28504736 7.528 ENSMUST00000063465.4
Wnt5a
wingless-related MMTV integration site 5A
chr2_-_66410064 7.186 ENSMUST00000112366.1
Scn1a
sodium channel, voltage-gated, type I, alpha
chr16_+_43503607 7.045 ENSMUST00000126100.1
ENSMUST00000123047.1
ENSMUST00000156981.1
Zbtb20


zinc finger and BTB domain containing 20


chr3_-_86548268 6.859 ENSMUST00000077524.3
Mab21l2
mab-21-like 2 (C. elegans)
chr4_-_53159885 6.720 ENSMUST00000030010.3
Abca1
ATP-binding cassette, sub-family A (ABC1), member 1
chr1_+_66175272 6.650 ENSMUST00000156636.2
Map2
microtubule-associated protein 2
chr17_-_90455872 6.546 ENSMUST00000174337.1
ENSMUST00000172466.1
Nrxn1

neurexin I

chr16_+_43363855 6.413 ENSMUST00000156367.1
Zbtb20
zinc finger and BTB domain containing 20
chr4_-_110290884 6.315 ENSMUST00000142722.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr13_+_54371340 6.278 ENSMUST00000026985.8
Cplx2
complexin 2
chr16_+_43247278 6.119 ENSMUST00000114691.1
ENSMUST00000079441.6
Zbtb20

zinc finger and BTB domain containing 20

chr14_-_88471396 6.095 ENSMUST00000061628.5
Pcdh20
protocadherin 20
chr10_-_102490418 6.000 ENSMUST00000020040.3
Nts
neurotensin
chr4_-_82505749 5.878 ENSMUST00000107245.2
ENSMUST00000107246.1
Nfib

nuclear factor I/B

chr2_+_67748212 5.824 ENSMUST00000180887.1
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr16_+_42907563 5.763 ENSMUST00000151244.1
ENSMUST00000114694.2
Zbtb20

zinc finger and BTB domain containing 20

chr3_+_156562141 5.744 ENSMUST00000175773.1
Negr1
neuronal growth regulator 1
chr3_+_156561950 5.566 ENSMUST00000041425.5
ENSMUST00000106065.1
Negr1

neuronal growth regulator 1

chr1_-_154725920 5.221 ENSMUST00000004214.8
Cacna1e
calcium channel, voltage-dependent, R type, alpha 1E subunit
chr14_-_79771305 5.190 ENSMUST00000039568.5
Pcdh8
protocadherin 8
chrX_-_88115632 5.137 ENSMUST00000113966.1
ENSMUST00000113964.1
Il1rapl1

interleukin 1 receptor accessory protein-like 1

chr9_+_27790947 5.011 ENSMUST00000115243.2
Opcml
opioid binding protein/cell adhesion molecule-like
chr1_+_66175286 4.836 ENSMUST00000114017.1
ENSMUST00000114015.1
Map2

microtubule-associated protein 2

chr7_-_37770757 4.643 ENSMUST00000176680.1
Zfp536
zinc finger protein 536
chr15_-_91191733 4.635 ENSMUST00000069511.6
Abcd2
ATP-binding cassette, sub-family D (ALD), member 2
chr9_+_64385675 4.582 ENSMUST00000068967.4
Megf11
multiple EGF-like-domains 11
chrX_+_136741821 4.304 ENSMUST00000089350.4
BC065397
cDNA sequence BC065397
chr9_-_91365756 4.279 ENSMUST00000034927.6
Zic1
zinc finger protein of the cerebellum 1
chr1_+_158362330 4.272 ENSMUST00000170718.1
Astn1
astrotactin 1
chr3_-_80802789 4.127 ENSMUST00000107745.1
ENSMUST00000075316.4
Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr16_+_43364145 4.079 ENSMUST00000148775.1
Zbtb20
zinc finger and BTB domain containing 20
chr12_+_52699297 4.021 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chr18_-_72351009 3.992 ENSMUST00000073379.5
Dcc
deleted in colorectal carcinoma
chr18_-_72351029 3.991 ENSMUST00000114943.3
Dcc
deleted in colorectal carcinoma
chr2_-_33942111 3.982 ENSMUST00000130988.1
ENSMUST00000127936.1
ENSMUST00000134271.1
Gm13403


predicted gene 13403


chr4_-_123527648 3.954 ENSMUST00000147228.1
Macf1
microtubule-actin crosslinking factor 1
chr4_-_110287479 3.843 ENSMUST00000106598.1
ENSMUST00000102723.4
ENSMUST00000153906.1
Elavl4


ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)


chr1_-_55226768 3.690 ENSMUST00000027121.8
ENSMUST00000114428.2
Rftn2

raftlin family member 2

chr9_-_91365778 3.650 ENSMUST00000065360.3
Zic1
zinc finger protein of the cerebellum 1
chrX_+_41401304 3.636 ENSMUST00000076349.5
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr12_-_64965496 3.470 ENSMUST00000021331.7
Klhl28
kelch-like 28
chr12_-_78980758 3.416 ENSMUST00000174072.1
Tmem229b
transmembrane protein 229B
chr8_-_67910911 3.404 ENSMUST00000093468.5
Psd3
pleckstrin and Sec7 domain containing 3
chr9_+_64385626 3.368 ENSMUST00000093829.2
ENSMUST00000118485.1
ENSMUST00000164113.1
Megf11


multiple EGF-like-domains 11


chr6_+_80018877 3.366 ENSMUST00000147663.1
ENSMUST00000128718.1
ENSMUST00000126005.1
ENSMUST00000133918.1
Lrrtm4



leucine rich repeat transmembrane neuronal 4



chr15_-_99820072 3.309 ENSMUST00000109024.2
Lima1
LIM domain and actin binding 1
chr2_-_114013619 3.303 ENSMUST00000090275.4
Gjd2
gap junction protein, delta 2
chrX_+_151198078 3.293 ENSMUST00000184730.1
ENSMUST00000184392.1
ENSMUST00000096285.4
Wnk3


WNK lysine deficient protein kinase 3


chr1_+_66386968 3.259 ENSMUST00000145419.1
Map2
microtubule-associated protein 2
chr16_-_59555752 3.242 ENSMUST00000179383.1
ENSMUST00000044604.8
Crybg3

beta-gamma crystallin domain containing 3

chr12_-_90738438 3.176 ENSMUST00000082432.3
Dio2
deiodinase, iodothyronine, type II
chr2_+_32721055 3.173 ENSMUST00000074248.4
Sh2d3c
SH2 domain containing 3C
chr5_+_98180866 3.146 ENSMUST00000112959.1
Prdm8
PR domain containing 8
chr6_+_149408973 3.047 ENSMUST00000086829.4
ENSMUST00000111513.2
Bicd1

bicaudal D homolog 1 (Drosophila)

chr11_+_29463735 3.002 ENSMUST00000155854.1
Ccdc88a
coiled coil domain containing 88A
chr5_+_13398688 2.959 ENSMUST00000125629.1
Sema3a
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr14_+_56887795 2.955 ENSMUST00000022511.8
Zmym2
zinc finger, MYM-type 2
chr9_-_40346290 2.932 ENSMUST00000121357.1
Gramd1b
GRAM domain containing 1B
chrX_-_70365052 2.913 ENSMUST00000101509.2
Ids
iduronate 2-sulfatase
chr6_-_137169678 2.891 ENSMUST00000119610.1
Rerg
RAS-like, estrogen-regulated, growth-inhibitor
chr7_-_37769624 2.878 ENSMUST00000175941.1
Zfp536
zinc finger protein 536
chr11_-_118909487 2.872 ENSMUST00000117731.1
ENSMUST00000106278.2
ENSMUST00000120061.1
ENSMUST00000017576.4
Rbfox3



RNA binding protein, fox-1 homolog (C. elegans) 3



chr17_-_37023349 2.807 ENSMUST00000102665.4
Mog
myelin oligodendrocyte glycoprotein
chr10_-_62880014 2.796 ENSMUST00000050826.7
Tet1
tet methylcytosine dioxygenase 1
chr1_-_169747634 2.772 ENSMUST00000027991.5
ENSMUST00000111357.1
Rgs4

regulator of G-protein signaling 4

chr4_-_91399984 2.755 ENSMUST00000102799.3
Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr7_+_67952817 2.738 ENSMUST00000005671.8
Igf1r
insulin-like growth factor I receptor
chr4_-_24430838 2.735 ENSMUST00000183964.1
RP23-35K5.2
RP23-35K5.2
chr2_+_84734050 2.735 ENSMUST00000090729.2
Ypel4
yippee-like 4 (Drosophila)
chr6_-_137169710 2.722 ENSMUST00000117919.1
Rerg
RAS-like, estrogen-regulated, growth-inhibitor
chr18_+_37489465 2.715 ENSMUST00000055949.2
Pcdhb18
protocadherin beta 18
chr4_+_144892813 2.707 ENSMUST00000105744.1
ENSMUST00000171001.1
Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr9_-_55919605 2.679 ENSMUST00000037408.8
Scaper
S phase cyclin A-associated protein in the ER
chr10_+_86302854 2.671 ENSMUST00000132307.1
Timp3
tissue inhibitor of metalloproteinase 3
chr2_+_65845833 2.653 ENSMUST00000053910.3
Csrnp3
cysteine-serine-rich nuclear protein 3
chr9_+_118478182 2.652 ENSMUST00000111763.1
Eomes
eomesodermin homolog (Xenopus laevis)
chr1_-_69685937 2.638 ENSMUST00000027146.2
Ikzf2
IKAROS family zinc finger 2
chr5_-_122049822 2.633 ENSMUST00000111752.3
Cux2
cut-like homeobox 2
chr7_+_126950687 2.630 ENSMUST00000106333.1
Sez6l2
seizure related 6 homolog like 2
chr17_-_81649607 2.608 ENSMUST00000163680.2
ENSMUST00000086538.3
ENSMUST00000163123.1
Slc8a1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr7_+_126950518 2.594 ENSMUST00000106335.1
ENSMUST00000146017.1
Sez6l2

seizure related 6 homolog like 2

chr11_-_94297067 2.579 ENSMUST00000132623.2
Luc7l3
LUC7-like 3 (S. cerevisiae)
chr8_+_57455898 2.553 ENSMUST00000034023.3
Scrg1
scrapie responsive gene 1
chr17_+_21566988 2.545 ENSMUST00000088787.5
Zfp948
zinc finger protein 948
chr14_+_13453937 2.537 ENSMUST00000153954.1
Synpr
synaptoporin
chr9_-_50693799 2.534 ENSMUST00000120622.1
Dixdc1
DIX domain containing 1
chr15_+_77084367 2.529 ENSMUST00000181870.1
1700109K24Rik
RIKEN cDNA 1700109K24 gene
chr5_+_57718021 2.520 ENSMUST00000094783.3
ENSMUST00000068110.7
Pcdh7

protocadherin 7

chr13_+_94875600 2.468 ENSMUST00000022195.10
Otp
orthopedia homolog (Drosophila)
chr19_-_28911879 2.455 ENSMUST00000179171.1
AC163993.1
AC163993.1
chr5_-_103211251 2.438 ENSMUST00000060871.5
ENSMUST00000112846.1
ENSMUST00000170792.1
ENSMUST00000112847.2
Mapk10



mitogen-activated protein kinase 10



chrX_-_73869804 2.401 ENSMUST00000066576.5
ENSMUST00000114430.1
L1cam

L1 cell adhesion molecule

chr3_+_51559973 2.400 ENSMUST00000180404.1
5031434O11Rik
RIKEN cDNA 5031434O11 gene
chr11_-_84069179 2.398 ENSMUST00000138208.1
Dusp14
dual specificity phosphatase 14
chr10_-_110000219 2.393 ENSMUST00000032719.7
Nav3
neuron navigator 3
chrX_+_56609751 2.384 ENSMUST00000144068.1
Slc9a6
solute carrier family 9 (sodium/hydrogen exchanger), member 6
chr2_-_29253001 2.381 ENSMUST00000071201.4
Ntng2
netrin G2
chr19_+_26623419 2.361 ENSMUST00000176584.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chrX_+_41401128 2.346 ENSMUST00000115103.2
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr2_-_63184253 2.339 ENSMUST00000075052.3
ENSMUST00000112454.1
Kcnh7

potassium voltage-gated channel, subfamily H (eag-related), member 7

chr4_+_144893077 2.316 ENSMUST00000154208.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chrX_+_13071470 2.284 ENSMUST00000169594.2
Usp9x
ubiquitin specific peptidase 9, X chromosome
chr4_+_144893127 2.272 ENSMUST00000142808.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr1_+_158362261 2.246 ENSMUST00000046110.9
Astn1
astrotactin 1
chr1_-_38664947 2.244 ENSMUST00000039827.7
ENSMUST00000027250.7
Aff3

AF4/FMR2 family, member 3

chr4_-_135494499 2.238 ENSMUST00000105856.2
Nipal3
NIPA-like domain containing 3
chr6_+_141249161 2.234 ENSMUST00000043259.7
Pde3a
phosphodiesterase 3A, cGMP inhibited
chr8_+_40354303 2.225 ENSMUST00000136835.1
Micu3
mitochondrial calcium uptake family, member 3
chr1_+_6730135 2.204 ENSMUST00000155921.1
St18
suppression of tumorigenicity 18
chr12_+_73286779 2.189 ENSMUST00000140523.1
Slc38a6
solute carrier family 38, member 6
chr6_+_17749170 2.187 ENSMUST00000053148.7
ENSMUST00000115417.3
St7

suppression of tumorigenicity 7

chr11_-_84525514 2.175 ENSMUST00000018842.7
Lhx1
LIM homeobox protein 1
chr12_+_73286868 2.174 ENSMUST00000153941.1
ENSMUST00000122920.1
ENSMUST00000101313.3
Slc38a6


solute carrier family 38, member 6


chr4_+_116221590 2.166 ENSMUST00000147292.1
Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr11_-_19018956 2.164 ENSMUST00000068264.7
ENSMUST00000144988.1
ENSMUST00000185131.1
Meis1


Meis homeobox 1


chr16_+_44173271 2.156 ENSMUST00000088356.4
ENSMUST00000169582.1
Gm608

predicted gene 608

chr11_+_44617310 2.156 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
Ebf1


early B cell factor 1


chr7_-_35802968 2.153 ENSMUST00000061586.4
Zfp507
zinc finger protein 507
chrX_+_166344692 2.151 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
Gpm6b





glycoprotein m6b





chr13_+_109685994 2.150 ENSMUST00000074103.5
Pde4d
phosphodiesterase 4D, cAMP specific
chr1_-_133753681 2.132 ENSMUST00000125659.1
ENSMUST00000165602.2
ENSMUST00000048953.7
Atp2b4


ATPase, Ca++ transporting, plasma membrane 4


chr8_-_67818284 2.104 ENSMUST00000120071.1
Psd3
pleckstrin and Sec7 domain containing 3
chr14_+_13454010 2.081 ENSMUST00000112656.2
Synpr
synaptoporin
chr12_-_83439910 2.051 ENSMUST00000177801.1
Dpf3
D4, zinc and double PHD fingers, family 3
chr3_+_156561792 2.044 ENSMUST00000074015.4
Negr1
neuronal growth regulator 1
chr1_+_15287259 2.017 ENSMUST00000175681.1
Kcnb2
potassium voltage gated channel, Shab-related subfamily, member 2
chr4_+_101550411 2.013 ENSMUST00000094953.4
ENSMUST00000106933.1
Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr6_-_118780324 2.011 ENSMUST00000112793.3
ENSMUST00000075591.6
ENSMUST00000078320.7
ENSMUST00000112790.2
Cacna1c



calcium channel, voltage-dependent, L type, alpha 1C subunit



chrY_+_897782 2.011 ENSMUST00000055032.7
Kdm5d
lysine (K)-specific demethylase 5D
chr16_+_96467606 1.990 ENSMUST00000061739.8
Pcp4
Purkinje cell protein 4
chr6_-_120038647 1.990 ENSMUST00000088646.5
ENSMUST00000177761.1
ENSMUST00000088644.6
ENSMUST00000060043.6
Wnk1



WNK lysine deficient protein kinase 1



chr10_-_42276744 1.978 ENSMUST00000105502.1
ENSMUST00000105501.1
Foxo3

forkhead box O3

chr12_+_102948843 1.975 ENSMUST00000101099.5
Unc79
unc-79 homolog (C. elegans)
chr2_+_68861564 1.968 ENSMUST00000176018.1
Cers6
ceramide synthase 6
chr4_+_102760294 1.960 ENSMUST00000072481.5
ENSMUST00000156596.1
ENSMUST00000080728.6
ENSMUST00000106882.2
Sgip1



SH3-domain GRB2-like (endophilin) interacting protein 1



chr8_+_128359065 1.954 ENSMUST00000026917.8
Nrp1
neuropilin 1
chr5_-_106458440 1.952 ENSMUST00000086795.6
Barhl2
BarH-like 2 (Drosophila)
chr4_+_11704439 1.929 ENSMUST00000108304.2
Gem
GTP binding protein (gene overexpressed in skeletal muscle)
chr9_+_118478344 1.923 ENSMUST00000035020.8
Eomes
eomesodermin homolog (Xenopus laevis)
chr1_+_34160253 1.922 ENSMUST00000183302.1
Dst
dystonin
chr5_-_70842617 1.907 ENSMUST00000031119.1
Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr2_-_7396192 1.906 ENSMUST00000137733.2
Celf2
CUGBP, Elav-like family member 2
chr14_+_27622433 1.897 ENSMUST00000090302.5
Erc2
ELKS/RAB6-interacting/CAST family member 2
chr15_+_40655020 1.896 ENSMUST00000053467.4
Zfpm2
zinc finger protein, multitype 2
chr5_-_99729039 1.895 ENSMUST00000146396.1
ENSMUST00000161148.1
ENSMUST00000161516.1
A930011G23Rik


RIKEN cDNA A930011G23 gene


chr4_-_110286581 1.873 ENSMUST00000138972.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr1_-_190169399 1.865 ENSMUST00000010319.7
Prox1
prospero-related homeobox 1
chr3_-_85746266 1.864 ENSMUST00000118408.1
Fam160a1
family with sequence similarity 160, member A1
chr10_-_95415283 1.846 ENSMUST00000119917.1
Socs2
suppressor of cytokine signaling 2
chr1_-_165934900 1.842 ENSMUST00000069609.5
ENSMUST00000111427.2
ENSMUST00000111426.4
Pou2f1


POU domain, class 2, transcription factor 1


chr17_+_21657582 1.839 ENSMUST00000039726.7
3110052M02Rik
RIKEN cDNA 3110052M02 gene
chr5_-_63968867 1.833 ENSMUST00000154169.1
Rell1
RELT-like 1
chr1_+_118389058 1.828 ENSMUST00000049404.6
ENSMUST00000070989.7
ENSMUST00000165223.1
ENSMUST00000178710.1
Clasp1



CLIP associating protein 1



chr2_-_116064721 1.828 ENSMUST00000110906.2
Meis2
Meis homeobox 2
chr13_-_23430826 1.825 ENSMUST00000153753.1
ENSMUST00000141543.1
C230035I16Rik

RIKEN cDNA C230035I16 gene

chr10_+_60106452 1.801 ENSMUST00000165024.2
Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr2_-_6722187 1.798 ENSMUST00000182657.1
Celf2
CUGBP, Elav-like family member 2
chr17_+_21491256 1.783 ENSMUST00000076664.6
Zfp53
zinc finger protein 53
chr5_-_72559599 1.782 ENSMUST00000074948.4
ENSMUST00000087216.5
Nfxl1

nuclear transcription factor, X-box binding-like 1

chr14_+_120275669 1.752 ENSMUST00000088419.6
ENSMUST00000167459.1
Mbnl2

muscleblind-like 2

chr4_-_20778527 1.744 ENSMUST00000119374.1
Nkain3
Na+/K+ transporting ATPase interacting 3
chr2_+_4017727 1.739 ENSMUST00000177457.1
Frmd4a
FERM domain containing 4A
chr7_+_126950837 1.738 ENSMUST00000106332.1
Sez6l2
seizure related 6 homolog like 2
chr18_+_33464163 1.736 ENSMUST00000097634.3
Gm10549
predicted gene 10549
chr3_-_73056943 1.733 ENSMUST00000059407.7
Slitrk3
SLIT and NTRK-like family, member 3
chr6_+_92092369 1.716 ENSMUST00000113463.1
Nr2c2
nuclear receptor subfamily 2, group C, member 2
chr11_-_69758223 1.714 ENSMUST00000071213.3
Polr2a
polymerase (RNA) II (DNA directed) polypeptide A
chr17_-_35703971 1.692 ENSMUST00000148065.1
Ddr1
discoidin domain receptor family, member 1
chr4_+_53713998 1.677 ENSMUST00000128667.1
Fktn
fukutin
chr10_+_60106198 1.676 ENSMUST00000121820.2
Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr16_+_43235856 1.672 ENSMUST00000146708.1
Zbtb20
zinc finger and BTB domain containing 20
chr2_-_116065047 1.671 ENSMUST00000028639.6
ENSMUST00000102538.4
Meis2

Meis homeobox 2

chrX_-_108834303 1.656 ENSMUST00000101283.3
ENSMUST00000150434.1
Brwd3

bromodomain and WD repeat domain containing 3

chrX_-_105929206 1.653 ENSMUST00000134381.1
ENSMUST00000154866.1
Atrx

alpha thalassemia/mental retardation syndrome X-linked homolog (human)

chr7_+_75701965 1.652 ENSMUST00000094307.3
Akap13
A kinase (PRKA) anchor protein 13
chr1_-_118982551 1.652 ENSMUST00000159678.1
Gli2
GLI-Kruppel family member GLI2
chr13_+_42709482 1.638 ENSMUST00000066928.5
ENSMUST00000148891.1
Phactr1

phosphatase and actin regulator 1

chr10_+_67185730 1.637 ENSMUST00000173689.1
Jmjd1c
jumonji domain containing 1C
chr1_+_66321708 1.623 ENSMUST00000114013.1
Map2
microtubule-associated protein 2
chr1_+_15712303 1.623 ENSMUST00000170146.1
Kcnb2
potassium voltage gated channel, Shab-related subfamily, member 2
chr1_+_6730051 1.622 ENSMUST00000043578.6
ENSMUST00000131467.1
ENSMUST00000150761.1
ENSMUST00000151281.1
St18



suppression of tumorigenicity 18



chr8_-_4217133 1.615 ENSMUST00000175906.1
BC068157
cDNA sequence BC068157
chr3_+_96576984 1.605 ENSMUST00000148290.1
Gm16253
predicted gene 16253
chr4_+_133369702 1.603 ENSMUST00000030669.7
Slc9a1
solute carrier family 9 (sodium/hydrogen exchanger), member 1
chr4_+_8691303 1.600 ENSMUST00000051558.3
Chd7
chromodomain helicase DNA binding protein 7
chr11_-_69605829 1.598 ENSMUST00000047889.6
Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr2_+_3713449 1.598 ENSMUST00000027965.4
Fam107b
family with sequence similarity 107, member B
chr2_+_79255500 1.579 ENSMUST00000099972.4
Itga4
integrin alpha 4
chr1_+_136467958 1.579 ENSMUST00000047817.6
Kif14
kinesin family member 14
chrX_+_56609843 1.576 ENSMUST00000077741.5
ENSMUST00000114784.2
Slc9a6

solute carrier family 9 (sodium/hydrogen exchanger), member 6

chr11_+_97798995 1.558 ENSMUST00000143571.1
Lasp1
LIM and SH3 protein 1

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
9.8 29.4 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
3.9 15.5 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
3.2 9.7 GO:0060067 cervix development(GO:0060067)
2.3 9.1 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
1.7 6.7 GO:0055099 response to high density lipoprotein particle(GO:0055099) platelet dense granule organization(GO:0060155)
1.6 9.6 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
1.5 4.6 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
1.4 7.2 GO:2000481 positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
1.3 5.1 GO:0097105 presynaptic membrane assembly(GO:0097105)
1.2 4.8 GO:0021698 cerebellar cortex structural organization(GO:0021698)
1.2 3.5 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
1.1 3.3 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
1.1 1.1 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
1.1 4.2 GO:0097393 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
1.1 3.2 GO:1900275 negative regulation of phospholipase C activity(GO:1900275)
1.0 4.9 GO:0021856 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.9 4.7 GO:0033227 dsRNA transport(GO:0033227)
0.9 10.1 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.9 2.7 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.8 4.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.8 1.7 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.8 6.5 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.8 8.1 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.8 4.0 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.8 31.3 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.8 12.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.7 6.7 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.7 6.5 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.7 2.7 GO:0044849 estrous cycle(GO:0044849) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.7 2.7 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.7 3.9 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.6 1.9 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.6 1.2 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.6 1.7 GO:0002331 pre-B cell allelic exclusion(GO:0002331) signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434) regulation of microglial cell activation(GO:1903978) telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.6 2.3 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.6 3.4 GO:0032196 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) transposition(GO:0032196)
0.6 2.8 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.5 2.5 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.5 1.5 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.5 2.0 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.5 4.0 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.5 2.0 GO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300)
0.5 2.4 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.5 1.9 GO:0046684 response to pyrethroid(GO:0046684)
0.5 1.4 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.5 0.9 GO:2000790 regulation of mesenchymal cell proliferation involved in lung development(GO:2000790) negative regulation of mesenchymal cell proliferation involved in lung development(GO:2000791)
0.5 0.5 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.5 4.6 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.5 3.2 GO:0019336 phenol-containing compound catabolic process(GO:0019336)
0.4 6.1 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.4 2.2 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.4 0.9 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.4 2.1 GO:0035063 nuclear speck organization(GO:0035063)
0.4 2.1 GO:0060690 epithelial cell differentiation involved in salivary gland development(GO:0060690)
0.4 1.7 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.4 0.4 GO:0045061 positive thymic T cell selection(GO:0045059) thymic T cell selection(GO:0045061)
0.4 18.0 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.4 2.4 GO:0007258 JUN phosphorylation(GO:0007258)
0.4 2.0 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.4 1.6 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.4 1.6 GO:0050904 diapedesis(GO:0050904)
0.4 1.5 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.4 1.1 GO:0019085 early viral transcription(GO:0019085)
0.4 0.4 GO:2000426 negative regulation of apoptotic cell clearance(GO:2000426)
0.4 1.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.4 3.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.4 1.1 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.3 0.7 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.3 1.4 GO:0097476 spinal cord motor neuron migration(GO:0097476)
0.3 2.4 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.3 2.0 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.3 2.0 GO:0072318 clathrin coat disassembly(GO:0072318)
0.3 7.4 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.3 3.3 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.3 2.6 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.3 4.6 GO:1901629 regulation of presynaptic membrane organization(GO:1901629)
0.3 1.0 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.3 0.6 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.3 0.6 GO:0002730 regulation of dendritic cell cytokine production(GO:0002730)
0.3 1.0 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.3 1.0 GO:1904170 interleukin-1 alpha secretion(GO:0050703) regulation of bleb assembly(GO:1904170)
0.3 0.3 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.3 2.2 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.3 1.5 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.3 0.9 GO:0002182 cytoplasmic translational elongation(GO:0002182) thermoception(GO:0050955) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.3 4.8 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.3 7.1 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.3 1.2 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.3 12.3 GO:0006376 mRNA splice site selection(GO:0006376)
0.3 0.6 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.3 16.2 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.3 3.2 GO:0060539 diaphragm development(GO:0060539)
0.3 0.9 GO:1900736 regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.3 0.8 GO:0008594 photoreceptor cell morphogenesis(GO:0008594)
0.3 2.5 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.3 1.1 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.3 2.4 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.3 11.0 GO:2001222 regulation of neuron migration(GO:2001222)
0.3 1.3 GO:0089700 protein kinase D signaling(GO:0089700)
0.3 0.8 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.3 1.8 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.3 0.8 GO:0015793 glycerol transport(GO:0015793)
0.3 1.0 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.3 1.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.3 3.3 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.3 1.0 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.3 1.0 GO:0070459 prolactin secretion(GO:0070459)
0.2 2.0 GO:0048149 behavioral response to ethanol(GO:0048149)
0.2 1.7 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.2 2.9 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.2 1.0 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.2 3.3 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.2 1.0 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.2 0.7 GO:0019858 cytosine metabolic process(GO:0019858)
0.2 0.7 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.2 1.3 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.2 0.7 GO:0007525 somatic muscle development(GO:0007525)
0.2 0.4 GO:0002578 negative regulation of antigen processing and presentation(GO:0002578)
0.2 3.5 GO:0010715 regulation of extracellular matrix disassembly(GO:0010715)
0.2 0.4 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.2 5.7 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2 1.5 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.2 1.7 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.2 3.8 GO:0015693 magnesium ion transport(GO:0015693)
0.2 0.6 GO:0048686 regulation of sprouting of injured axon(GO:0048686) positive regulation of sprouting of injured axon(GO:0048687) regulation of axon extension involved in regeneration(GO:0048690) positive regulation of axon extension involved in regeneration(GO:0048691)
0.2 6.2 GO:0010842 retina layer formation(GO:0010842)
0.2 6.9 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.2 2.0 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.2 0.6 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.2 0.4 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.2 13.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2 1.0 GO:0061038 uterus morphogenesis(GO:0061038)
0.2 1.4 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.2 1.0 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.2 0.8 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.2 1.3 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.2 1.3 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.2 0.7 GO:0061386 closure of optic fissure(GO:0061386)
0.2 1.1 GO:0098964 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.2 0.5 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.2 2.9 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.2 0.9 GO:0051013 microtubule severing(GO:0051013)
0.2 1.1 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.2 2.7 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.2 0.4 GO:0035095 behavioral response to nicotine(GO:0035095)
0.2 1.4 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.2 0.9 GO:0051012 microtubule sliding(GO:0051012)
0.2 3.7 GO:0035855 megakaryocyte development(GO:0035855)
0.2 0.3 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.2 8.0 GO:0001919 regulation of receptor recycling(GO:0001919)
0.2 0.5 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.2 0.5 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 0.8 GO:0097167 circadian regulation of translation(GO:0097167)
0.2 0.3 GO:2000551 regulation of T-helper 2 cell cytokine production(GO:2000551) positive regulation of T-helper 2 cell cytokine production(GO:2000553)
0.2 1.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.2 1.4 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1 1.3 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.1 2.5 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.1 0.6 GO:0032876 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.1 2.6 GO:0007614 short-term memory(GO:0007614)
0.1 0.7 GO:0014842 regulation of skeletal muscle satellite cell proliferation(GO:0014842)
0.1 0.6 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 1.0 GO:0007296 vitellogenesis(GO:0007296)
0.1 1.1 GO:0060137 maternal process involved in parturition(GO:0060137)
0.1 0.7 GO:0090383 phagosome acidification(GO:0090383)
0.1 0.3 GO:0060763 mammary duct terminal end bud growth(GO:0060763)
0.1 1.0 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.6 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.1 1.5 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1 0.4 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 1.2 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.1 0.3 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.1 0.5 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.1 0.5 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 1.2 GO:0001881 receptor recycling(GO:0001881)
0.1 0.4 GO:1904245 regulation of polynucleotide adenylyltransferase activity(GO:1904245)
0.1 1.4 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.1 0.5 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.1 0.4 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.1 0.5 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) dibasic protein processing(GO:0090472)
0.1 1.3 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) cellular response to magnesium ion(GO:0071286) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 2.7 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 0.7 GO:0048840 otolith development(GO:0048840)
0.1 0.3 GO:0008228 opsonization(GO:0008228)
0.1 0.6 GO:2000325 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.1 5.1 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.1 0.6 GO:0070417 cellular response to cold(GO:0070417)
0.1 0.5 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 0.9 GO:0006020 inositol metabolic process(GO:0006020)
0.1 0.4 GO:0071105 response to interleukin-11(GO:0071105)
0.1 0.9 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.4 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1 0.9 GO:0048102 autophagic cell death(GO:0048102)
0.1 0.3 GO:0030473 cell motility involved in cerebral cortex radial glia guided migration(GO:0021814) modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration(GO:0021815) nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473) nuclear migration along microfilament(GO:0031022)
0.1 0.5 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 3.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 0.6 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 11.8 GO:1900006 positive regulation of dendrite development(GO:1900006)
0.1 0.4 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 0.2 GO:1903273 regulation of sodium ion export(GO:1903273) positive regulation of sodium ion export(GO:1903275) regulation of sodium ion export from cell(GO:1903276) positive regulation of sodium ion export from cell(GO:1903278)
0.1 1.3 GO:0016486 peptide hormone processing(GO:0016486)
0.1 0.3 GO:0046958 nonassociative learning(GO:0046958)
0.1 0.2 GO:0060596 mammary placode formation(GO:0060596)
0.1 0.4 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.1 1.6 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 0.6 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1 0.4 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.1 1.2 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 1.6 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.1 0.6 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.1 0.6 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.1 0.9 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 1.2 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.1 0.3 GO:0072382 minus-end-directed vesicle transport along microtubule(GO:0072382) regulation of metaphase plate congression(GO:0090235)
0.1 0.6 GO:0060074 synapse maturation(GO:0060074)
0.1 1.0 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.4 GO:0097646 dimeric G-protein coupled receptor signaling pathway(GO:0038042) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 0.6 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.1 0.7 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 0.9 GO:0048194 Golgi vesicle budding(GO:0048194)
0.1 0.6 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.7 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.1 0.2 GO:2000821 regulation of grooming behavior(GO:2000821)
0.1 0.4 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 0.3 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 1.3 GO:0035411 catenin import into nucleus(GO:0035411)
0.1 0.3 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.1 0.8 GO:0042574 retinal metabolic process(GO:0042574)
0.1 0.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.4 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.7 GO:0042118 endothelial cell activation(GO:0042118)
0.1 1.0 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 0.4 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.1 0.4 GO:0006477 protein sulfation(GO:0006477)
0.1 0.6 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.1 0.9 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.1 0.7 GO:0006612 protein targeting to membrane(GO:0006612)
0.1 2.8 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 0.6 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 0.5 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.9 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 8.3 GO:0045727 positive regulation of translation(GO:0045727)
0.1 0.4 GO:0031053 production of siRNA involved in RNA interference(GO:0030422) primary miRNA processing(GO:0031053)
0.1 0.3 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.1 0.8 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.1 0.6 GO:0043383 negative T cell selection(GO:0043383) negative thymic T cell selection(GO:0045060)
0.1 0.9 GO:0009404 toxin metabolic process(GO:0009404)
0.1 1.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.4 GO:1902414 protein localization to cell junction(GO:1902414)
0.1 0.2 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.1 0.9 GO:0060117 auditory receptor cell development(GO:0060117)
0.1 0.8 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 0.6 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.1 0.8 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.1 1.3 GO:0048305 immunoglobulin secretion(GO:0048305)
0.1 2.7 GO:0043242 negative regulation of protein complex disassembly(GO:0043242)
0.1 3.2 GO:0008542 visual learning(GO:0008542)
0.1 0.4 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.1 1.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 0.4 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.5 GO:0035735 microtubule anchoring at centrosome(GO:0034454) intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 0.6 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 0.9 GO:0046697 decidualization(GO:0046697)
0.1 0.6 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.1 0.4 GO:0090527 actin filament reorganization(GO:0090527)
0.1 0.6 GO:0006691 leukotriene metabolic process(GO:0006691)
0.1 0.4 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.1 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 1.3 GO:0002115 store-operated calcium entry(GO:0002115)
0.1 0.3 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.1 0.7 GO:0007616 long-term memory(GO:0007616)
0.1 1.0 GO:0048535 lymph node development(GO:0048535)
0.1 0.5 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 1.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.5 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 0.3 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.7 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.1 0.8 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 1.0 GO:0001553 luteinization(GO:0001553)
0.1 0.2 GO:0044805 late nucleophagy(GO:0044805)
0.1 0.1 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.1 0.2 GO:1901678 iron coordination entity transport(GO:1901678)
0.1 2.2 GO:0007628 adult walking behavior(GO:0007628)
0.1 0.7 GO:0001675 acrosome assembly(GO:0001675)
0.1 0.5 GO:0030259 lipid glycosylation(GO:0030259)
0.1 0.4 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 0.1 GO:1903298 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298) intrinsic apoptotic signaling pathway in response to hypoxia(GO:1990144)
0.1 0.2 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.1 0.4 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1 0.9 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 3.7 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 0.1 GO:0098705 plasma membrane copper ion transport(GO:0015679) copper ion import across plasma membrane(GO:0098705) copper ion import into cell(GO:1902861)
0.1 0.4 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 0.3 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 0.6 GO:0036120 response to platelet-derived growth factor(GO:0036119) cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.1 1.0 GO:0021859 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.1 0.7 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 0.5 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.3 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.1 0.4 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.1 0.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.2 GO:0035826 rubidium ion transport(GO:0035826)
0.1 0.3 GO:0015074 DNA integration(GO:0015074)
0.1 0.1 GO:2000664 positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
0.1 0.3 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.5 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.0 1.0 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.5 GO:0042659 regulation of cell fate specification(GO:0042659)
0.0 0.7 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.4 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.6 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.3 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0 1.3 GO:0001947 heart looping(GO:0001947)
0.0 0.6 GO:0006903 vesicle targeting(GO:0006903)
0.0 1.2 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.3 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.5 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.0 1.2 GO:0048821 erythrocyte development(GO:0048821)
0.0 0.2 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0 0.5 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.2 GO:0035608 protein deglutamylation(GO:0035608)
0.0 0.6 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.1 GO:0072176 nephric duct development(GO:0072176) nephric duct morphogenesis(GO:0072178)
0.0 0.2 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.0 2.5 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.3 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.2 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.3 GO:0009072 aromatic amino acid family metabolic process(GO:0009072)
0.0 0.5 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.0 0.2 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.5 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 4.4 GO:0071805 potassium ion transmembrane transport(GO:0071805)
0.0 0.5 GO:0032620 interleukin-17 production(GO:0032620)
0.0 0.5 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.3 GO:0035065 regulation of histone acetylation(GO:0035065)
0.0 0.1 GO:0048162 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.0 0.5 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.0 0.3 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.5 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.3 GO:0030813 positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.0 0.3 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0010819 regulation of T cell chemotaxis(GO:0010819)
0.0 1.4 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.7 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.1 GO:0032439 endosome localization(GO:0032439)
0.0 1.5 GO:0007091 metaphase/anaphase transition of mitotic cell cycle(GO:0007091) metaphase/anaphase transition of cell cycle(GO:0044784)
0.0 0.0 GO:0070829 heterochromatin maintenance(GO:0070829)
0.0 0.4 GO:0010225 response to UV-C(GO:0010225)
0.0 0.0 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.0 0.3 GO:0015813 L-glutamate transport(GO:0015813)
0.0 0.3 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.3 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 0.4 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.4 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 0.1 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.2 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.2 GO:0043084 penile erection(GO:0043084)
0.0 0.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.3 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.1 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.1 GO:0099612 protein localization to axon(GO:0099612)
0.0 0.2 GO:0014887 cardiac muscle adaptation(GO:0014887)
0.0 0.4 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0 0.0 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0 0.7 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.9 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.3 GO:0044804 nucleophagy(GO:0044804)
0.0 0.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.1 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.2 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 2.9 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.1 GO:0036233 glycine import(GO:0036233)
0.0 1.3 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.2 GO:0015838 amino-acid betaine transport(GO:0015838)
0.0 0.1 GO:0048643 positive regulation of skeletal muscle tissue development(GO:0048643)
0.0 0.6 GO:0021591 ventricular system development(GO:0021591)
0.0 0.3 GO:0032528 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0 0.3 GO:0071347 cellular response to interleukin-1(GO:0071347)
0.0 0.5 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:0043586 tongue development(GO:0043586)
0.0 0.1 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.3 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.0 GO:2000544 cell chemotaxis to fibroblast growth factor(GO:0035766) endothelial cell chemotaxis to fibroblast growth factor(GO:0035768) regulation of endothelial tube morphogenesis(GO:1901509) regulation of cell chemotaxis to fibroblast growth factor(GO:1904847) regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000544)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.4 GO:0043113 receptor clustering(GO:0043113)
0.0 0.5 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.5 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
0.0 1.3 GO:0007416 synapse assembly(GO:0007416)
0.0 0.5 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.4 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.2 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.2 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 1.2 GO:0000725 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0 2.0 GO:0010976 positive regulation of neuron projection development(GO:0010976)
0.0 0.2 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.5 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.8 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.3 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 0.2 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.0 0.2 GO:0016052 carbohydrate catabolic process(GO:0016052)
0.0 0.1 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 0.3 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 0.9 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.1 GO:0036506 maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 0.4 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.2 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.1 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.2 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.1 GO:0007588 excretion(GO:0007588)
0.0 0.1 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.1 GO:0050927 positive regulation of positive chemotaxis(GO:0050927)
0.0 0.0 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.2 GO:0050798 activated T cell proliferation(GO:0050798)
0.0 0.1 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.3 GO:0031018 endocrine pancreas development(GO:0031018)
0.0 0.1 GO:0034340 response to type I interferon(GO:0034340)
0.0 0.1 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.7 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.0 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.4 GO:1901998 toxin transport(GO:1901998)
0.0 0.2 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.0 0.2 GO:0032094 response to food(GO:0032094)
0.0 0.1 GO:0033234 regulation of protein sumoylation(GO:0033233) negative regulation of protein sumoylation(GO:0033234)
0.0 0.1 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 31.7 GO:0030478 actin cap(GO:0030478)
2.1 18.6 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
1.6 6.3 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
1.1 9.6 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
1.1 4.2 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.9 5.2 GO:0044308 axonal spine(GO:0044308)
0.8 12.6 GO:0042788 polysomal ribosome(GO:0042788)
0.8 16.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.7 8.2 GO:0032584 growth cone membrane(GO:0032584)
0.7 2.8 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.6 9.1 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.5 2.5 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.5 1.9 GO:0031673 H zone(GO:0031673)
0.5 1.8 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.4 1.3 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.4 7.9 GO:0032279 asymmetric synapse(GO:0032279)
0.4 3.3 GO:0033648 host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.4 1.2 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.4 1.5 GO:0099569 presynaptic cytoskeleton(GO:0099569)
0.4 3.2 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.3 3.1 GO:0005883 neurofilament(GO:0005883)
0.3 5.9 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.3 1.0 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.3 2.0 GO:0033503 HULC complex(GO:0033503)
0.3 1.1 GO:0097447 dendritic tree(GO:0097447)
0.3 5.9 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.2 1.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.2 2.2 GO:0044294 dendritic growth cone(GO:0044294)
0.2 4.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.2 0.7 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.2 0.7 GO:0071437 invadopodium(GO:0071437)
0.2 0.2 GO:1904949 ATPase complex(GO:1904949)
0.2 0.7 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.2 0.9 GO:0044307 dendritic branch(GO:0044307)
0.2 5.1 GO:0071565 nBAF complex(GO:0071565)
0.2 0.8 GO:0031983 vesicle lumen(GO:0031983)
0.2 4.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.2 7.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 9.8 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.2 0.9 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.2 0.9 GO:0070876 SOSS complex(GO:0070876)
0.2 0.5 GO:0016939 kinesin II complex(GO:0016939)
0.2 1.9 GO:0005915 zonula adherens(GO:0005915)
0.2 1.5 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.2 0.5 GO:0005588 collagen type V trimer(GO:0005588)
0.2 1.5 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 0.7 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.2 3.3 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.2 0.8 GO:0030314 junctional membrane complex(GO:0030314)
0.2 0.5 GO:0005899 insulin receptor complex(GO:0005899)
0.2 0.6 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.2 2.0 GO:0000974 Prp19 complex(GO:0000974)
0.2 0.6 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.2 2.0 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 1.2 GO:0097165 nuclear stress granule(GO:0097165)
0.1 0.9 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.1 1.8 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.1 2.6 GO:0071004 U2-type prespliceosome(GO:0071004)
0.1 0.8 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.8 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 2.5 GO:0097228 sperm principal piece(GO:0097228)
0.1 0.9 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 0.4 GO:1903095 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.1 3.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.9 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 1.7 GO:0097542 ciliary tip(GO:0097542)
0.1 0.6 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 1.0 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 1.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 1.2 GO:0070545 PeBoW complex(GO:0070545)
0.1 3.5 GO:0051233 spindle midzone(GO:0051233)
0.1 14.0 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 3.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 0.5 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1 0.5 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 3.4 GO:0030673 axolemma(GO:0030673)
0.1 0.8 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1 0.7 GO:0097227 sperm annulus(GO:0097227)
0.1 1.8 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 0.4 GO:0060187 cell pole(GO:0060187)
0.1 0.8 GO:0002177 manchette(GO:0002177)
0.1 0.9 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 0.4 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 5.9 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 0.4 GO:0005667 transcription factor complex(GO:0005667)
0.1 1.1 GO:0042581 specific granule(GO:0042581)
0.1 0.4 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1 0.1 GO:0043512 inhibin A complex(GO:0043512)
0.1 0.2 GO:0030667 secretory granule membrane(GO:0030667)
0.1 1.0 GO:0005922 connexon complex(GO:0005922)
0.1 5.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 0.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.3 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.1 2.2 GO:0042734 presynaptic membrane(GO:0042734)
0.1 3.3 GO:1990391 DNA repair complex(GO:1990391)
0.1 0.5 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.4 GO:0036038 MKS complex(GO:0036038)
0.1 0.9 GO:0031985 Golgi cisterna(GO:0031985)
0.1 4.8 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 0.7 GO:0002080 acrosomal membrane(GO:0002080)
0.1 2.9 GO:0005801 cis-Golgi network(GO:0005801)
0.1 0.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 1.7 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 0.5 GO:0097470 ribbon synapse(GO:0097470)
0.1 12.9 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 2.5 GO:0005876 spindle microtubule(GO:0005876)
0.1 1.2 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.3 GO:1990246 uniplex complex(GO:1990246)
0.1 0.3 GO:0070695 FHF complex(GO:0070695)
0.1 0.5 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 3.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.3 GO:0030891 VCB complex(GO:0030891)
0.1 0.2 GO:0044292 dendrite terminus(GO:0044292)
0.1 0.4 GO:0042629 mast cell granule(GO:0042629)
0.1 0.4 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 0.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 1.5 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.8 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.4 GO:0055037 recycling endosome(GO:0055037)
0.0 3.7 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 0.5 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.3 GO:0071439 clathrin complex(GO:0071439)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.6 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 3.4 GO:0005814 centriole(GO:0005814)
0.0 1.1 GO:0097060 synaptic membrane(GO:0097060)
0.0 0.3 GO:0001739 sex chromatin(GO:0001739)
0.0 1.3 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 1.3 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.6 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.3 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.4 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 4.4 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.7 GO:0001726 ruffle(GO:0001726)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.7 GO:0099738 cell cortex region(GO:0099738)
0.0 0.1 GO:0005694 chromosome(GO:0005694)
0.0 0.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 2.5 GO:0030427 site of polarized growth(GO:0030427)
0.0 1.2 GO:0005776 autophagosome(GO:0005776)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 2.1 GO:0044306 neuron projection terminus(GO:0044306)
0.0 0.2 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 1.5 GO:0005811 lipid particle(GO:0005811)
0.0 0.8 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.8 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.9 GO:0031941 filamentous actin(GO:0031941)
0.0 0.3 GO:0005902 microvillus(GO:0005902)
0.0 0.5 GO:0035371 microtubule plus-end(GO:0035371)
0.0 1.1 GO:0042641 actomyosin(GO:0042641)
0.0 0.8 GO:0034702 ion channel complex(GO:0034702)
0.0 0.3 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.6 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.2 GO:0002102 podosome(GO:0002102)
0.0 1.2 GO:0030027 lamellipodium(GO:0030027)
0.0 0.4 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 11.8 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.5 GO:0031201 SNARE complex(GO:0031201)
0.0 0.1 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.1 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0097443 sorting endosome(GO:0097443)
0.0 1.1 GO:0045177 apical part of cell(GO:0045177)
0.0 1.4 GO:0016605 PML body(GO:0016605)
0.0 0.6 GO:0030139 endocytic vesicle(GO:0030139)
0.0 3.2 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.1 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0097223 sperm part(GO:0097223)
0.0 0.1 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.9 GO:0005815 microtubule organizing center(GO:0005815)
0.0 0.1 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0045111 intermediate filament(GO:0005882) intermediate filament cytoskeleton(GO:0045111)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 10.7 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
2.5 7.5 GO:0005110 frizzled-2 binding(GO:0005110)
2.4 29.4 GO:0050693 LBD domain binding(GO:0050693)
2.2 6.7 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
2.2 17.6 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
1.6 11.3 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
1.5 5.8 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
1.3 8.0 GO:0005042 netrin receptor activity(GO:0005042)
1.1 8.0 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
1.0 3.0 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.9 9.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.8 3.4 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.8 9.8 GO:0097109 neuroligin family protein binding(GO:0097109)
0.7 5.5 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.7 5.3 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.7 2.6 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.6 4.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.6 2.4 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.6 4.2 GO:0015616 DNA translocase activity(GO:0015616)
0.6 1.7 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.6 2.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.6 3.5 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.6 2.9 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.5 18.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.5 7.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.5 2.8 GO:0043559 insulin binding(GO:0043559)
0.4 8.8 GO:0031402 sodium ion binding(GO:0031402)
0.4 2.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.4 1.3 GO:0033680 ATP-dependent DNA/RNA helicase activity(GO:0033680)
0.4 3.7 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.4 3.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.4 3.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.4 3.9 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.4 1.1 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.4 1.8 GO:0043515 kinetochore binding(GO:0043515)
0.4 1.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.3 6.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.3 2.1 GO:0033691 sialic acid binding(GO:0033691)
0.3 2.7 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.3 1.0 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.3 6.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.3 1.0 GO:0030350 iron-responsive element binding(GO:0030350)
0.3 6.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.3 1.6 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.3 4.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.3 0.9 GO:0048019 receptor antagonist activity(GO:0048019)
0.3 2.0 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.3 4.0 GO:0043495 protein anchor(GO:0043495)
0.3 2.3 GO:0032051 clathrin light chain binding(GO:0032051)
0.3 0.8 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.3 0.8 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.3 1.3 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.3 0.8 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.2 1.0 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.2 0.7 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.2 1.0 GO:0048495 Roundabout binding(GO:0048495)
0.2 0.7 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.2 0.9 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.2 2.0 GO:0005523 tropomyosin binding(GO:0005523)
0.2 0.9 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.2 0.7 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.2 5.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.2 1.3 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.2 1.4 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.2 3.8 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.2 3.4 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.2 0.8 GO:0001639 PLC activating G-protein coupled glutamate receptor activity(GO:0001639) G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.2 2.6 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.2 1.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.2 0.6 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.2 5.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 1.0 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.2 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.2 5.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 7.0 GO:0017091 AU-rich element binding(GO:0017091)
0.2 1.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 1.8 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.2 0.5 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.2 2.9 GO:0050811 GABA receptor binding(GO:0050811)
0.2 0.7 GO:0050436 microfibril binding(GO:0050436)
0.2 3.8 GO:0043422 protein kinase B binding(GO:0043422)
0.2 10.6 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.2 0.3 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.2 2.5 GO:0070410 co-SMAD binding(GO:0070410)
0.2 1.0 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.2 0.6 GO:0042834 peptidoglycan binding(GO:0042834)
0.2 0.5 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.2 1.1 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.2 1.7 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.2 0.6 GO:0070012 oligopeptidase activity(GO:0070012)
0.1 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.7 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 3.8 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 8.1 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 0.6 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 2.5 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 2.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 1.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.7 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.1 1.7 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 0.4 GO:0016494 C-X-C chemokine receptor activity(GO:0016494) C-X-C chemokine binding(GO:0019958)
0.1 0.9 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 1.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.6 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.9 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 1.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.6 GO:0043532 angiostatin binding(GO:0043532)
0.1 0.4 GO:0050733 RS domain binding(GO:0050733)
0.1 1.0 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.5 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.1 1.2 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 0.7 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 0.2 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.1 0.2 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.1 0.5 GO:1903135 cupric ion binding(GO:1903135)
0.1 0.3 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.1 0.2 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 0.6 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.3 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.1 1.6 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.5 GO:0043426 MRF binding(GO:0043426)
0.1 0.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.5 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.6 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 2.9 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 0.5 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 1.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 2.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 1.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 17.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 1.0 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1 0.4 GO:0051393 alpha-actinin binding(GO:0051393)
0.1 1.1 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 3.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 2.5 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 0.3 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.1 0.5 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.1 0.3 GO:0003692 left-handed Z-DNA binding(GO:0003692)
0.1 2.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 0.4 GO:0070330 aromatase activity(GO:0070330)
0.1 0.3 GO:0046790 virion binding(GO:0046790)
0.1 0.7 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.1 0.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.5 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 1.6 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.5 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.7 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 2.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 3.5 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.1 0.4 GO:0070878 primary miRNA binding(GO:0070878)
0.1 0.4 GO:0097643 amylin receptor activity(GO:0097643)
0.1 0.5 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.5 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.1 0.2 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.1 1.0 GO:0005521 lamin binding(GO:0005521)
0.1 0.4 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.1 0.5 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.1 3.0 GO:0017022 myosin binding(GO:0017022)
0.1 0.4 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 1.0 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.1 0.1 GO:0005231 excitatory extracellular ligand-gated ion channel activity(GO:0005231)
0.1 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 0.5 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.4 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.5 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1 1.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 1.3 GO:0004697 protein kinase C activity(GO:0004697)
0.1 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.5 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.1 0.4 GO:0097001 ceramide binding(GO:0097001)
0.1 0.1 GO:0031687 A2A adenosine receptor binding(GO:0031687)
0.1 0.7 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 0.4 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 1.2 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 8.1 GO:0030674 protein binding, bridging(GO:0030674)
0.1 0.9 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.3 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.1 1.1 GO:0030276 clathrin binding(GO:0030276)
0.1 0.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.7 GO:0042166 acetylcholine binding(GO:0042166)
0.1 1.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 0.3 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 0.2 GO:0032450 alpha-1,4-glucosidase activity(GO:0004558) maltose alpha-glucosidase activity(GO:0032450)
0.1 7.5 GO:0017124 SH3 domain binding(GO:0017124)
0.1 2.0 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 1.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.4 GO:0042165 neurotransmitter binding(GO:0042165)
0.0 0.8 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.5 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 20.4 GO:0003779 actin binding(GO:0003779)
0.0 0.1 GO:0070697 activin receptor binding(GO:0070697)
0.0 0.6 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 4.4 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.5 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.5 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.5 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.7 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.7 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.6 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.8 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 0.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.8 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.9 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.2 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.4 GO:0043008 ATP-dependent protein binding(GO:0043008) calcium-independent phospholipase A2 activity(GO:0047499)
0.0 5.5 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.2 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.7 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.4 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.3 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.6 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.0 GO:0070052 collagen V binding(GO:0070052)
0.0 3.4 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 1.8 GO:0008013 beta-catenin binding(GO:0008013)
0.0 1.1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.7 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0016501 prostacyclin receptor activity(GO:0016501)
0.0 0.7 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.1 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.7 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.9 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.0 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.8 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 1.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 2.5 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.5 GO:0043236 laminin binding(GO:0043236)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.2 GO:0042805 actinin binding(GO:0042805)
0.0 1.2 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.6 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 8.9 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.3 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.5 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.3 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.3 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.3 GO:0048038 quinone binding(GO:0048038)
0.0 1.8 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.5 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.1 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.1 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.2 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558)
0.0 0.5 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 6.3 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.2 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.5 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.4 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.1 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.1 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.1 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0017046 peptide hormone binding(GO:0017046)
0.0 2.1 GO:0003924 GTPase activity(GO:0003924)
0.0 0.0 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.0 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.0 GO:0003996 acyl-CoA ligase activity(GO:0003996)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.7 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.3 12.4 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.2 12.7 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.2 11.3 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 15.7 PID_LKB1_PATHWAY LKB1 signaling events
0.2 5.9 PID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY EGF receptor (ErbB1) signaling pathway
0.1 1.7 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.1 7.9 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 5.9 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 0.7 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 2.0 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 4.8 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 1.6 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.1 1.0 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.1 5.1 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 0.1 PID_TXA2PATHWAY Thromboxane A2 receptor signaling
0.1 2.4 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.1 1.7 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 0.6 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 3.9 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.1 1.7 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.1 2.4 PID_RHOA_PATHWAY RhoA signaling pathway
0.1 1.0 PID_IL8_CXCR2_PATHWAY IL8- and CXCR2-mediated signaling events
0.1 1.9 ST_GA13_PATHWAY G alpha 13 Pathway
0.1 0.8 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 0.9 PID_CONE_PATHWAY Visual signal transduction: Cones
0.1 0.8 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 1.3 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.1 1.5 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.1 1.9 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.1 1.8 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.1 1.4 PID_ERBB4_PATHWAY ErbB4 signaling events
0.1 0.5 PID_VEGFR1_PATHWAY VEGFR1 specific signals
0.1 1.7 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.1 0.8 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.1 0.5 SIG_IL4RECEPTOR_IN_B_LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.6 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.5 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 1.8 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.8 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.2 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.0 0.6 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 0.7 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.0 0.5 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 1.3 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 0.3 PID_PI3KCI_PATHWAY Class I PI3K signaling events
0.0 0.2 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.0 1.6 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 0.3 PID_IL1_PATHWAY IL1-mediated signaling events
0.0 1.2 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.6 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 1.1 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.3 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.9 PID_CDC42_PATHWAY CDC42 signaling events
0.0 0.6 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 0.3 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.3 PID_REELIN_PATHWAY Reelin signaling pathway
0.0 0.4 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 0.5 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 0.2 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.2 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 0.2 SIG_BCR_SIGNALING_PATHWAY Members of the BCR signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 10.7 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.8 28.5 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.7 7.3 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.5 13.0 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.5 11.5 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.4 2.2 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.4 3.9 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.4 4.2 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.4 4.9 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.3 3.3 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.3 3.5 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.3 1.6 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2 10.0 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.2 3.9 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.2 0.6 REACTOME_PD1_SIGNALING Genes involved in PD-1 signaling
0.2 1.8 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.2 1.7 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.2 3.5 REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1 1.8 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 1.0 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 0.8 REACTOME_PEPTIDE_HORMONE_BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.1 1.4 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 4.3 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 2.9 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.1 2.5 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.1 0.1 REACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1 1.7 REACTOME_PHOSPHORYLATION_OF_THE_APC_C Genes involved in Phosphorylation of the APC/C
0.1 2.5 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.1 1.1 REACTOME_ELONGATION_ARREST_AND_RECOVERY Genes involved in Elongation arrest and recovery
0.1 0.8 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 7.1 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.1 0.4 REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.1 2.9 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.1 3.0 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.1 0.6 REACTOME_DEVELOPMENTAL_BIOLOGY Genes involved in Developmental Biology
0.1 1.0 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.1 0.6 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 1.0 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.2 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.1 1.1 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.1 1.5 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.1 0.8 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 6.3 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 1.5 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 1.4 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.1 0.9 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 1.0 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 0.5 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 0.8 REACTOME_G_ALPHA1213_SIGNALLING_EVENTS Genes involved in G alpha (12/13) signalling events
0.1 1.4 REACTOME_KINESINS Genes involved in Kinesins
0.0 0.5 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.2 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.4 REACTOME_MICRORNA_MIRNA_BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 1.3 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.9 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.8 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.3 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.2 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 4.1 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.4 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME_NOD1_2_SIGNALING_PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 2.5 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 2.2 REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS Genes involved in G alpha (z) signalling events
0.0 0.5 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.9 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.0 0.3 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.4 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.3 REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.6 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.8 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.2 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 1.6 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.7 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.3 REACTOME_ENOS_ACTIVATION_AND_REGULATION Genes involved in eNOS activation and regulation
0.0 0.2 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.4 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 1.1 REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.3 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.6 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 1.0 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.4 REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.6 REACTOME_RNA_POL_II_PRE_TRANSCRIPTION_EVENTS Genes involved in RNA Polymerase II Pre-transcription Events
0.0 0.2 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.3 REACTOME_ACYL_CHAIN_REMODELLING_OF_PC Genes involved in Acyl chain remodelling of PC
0.0 1.0 REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH Genes involved in NCAM signaling for neurite out-growth
0.0 0.4 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.4 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 0.3 REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.5 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.3 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions
0.0 0.6 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors