Motif ID: Foxf1

Z-value: 0.674


Transcription factors associated with Foxf1:

Gene SymbolEntrez IDGene Name
Foxf1 ENSMUSG00000042812.4 Foxf1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxf1mm10_v2_chr8_+_121084352_1210844740.247.6e-02Click!


Activity profile for motif Foxf1.

activity profile for motif Foxf1


Sorted Z-values histogram for motif Foxf1

Sorted Z-values for motif Foxf1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxf1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_68117713 4.728 ENSMUST00000112346.2
 B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr1_+_66386968 3.915 ENSMUST00000145419.1
 Map2
microtubule-associated protein 2
chr5_+_88583527 3.527 ENSMUST00000031229.6
 Rufy3
RUN and FYVE domain containing 3
chr7_-_4844665 3.402 ENSMUST00000066041.5
ENSMUST00000172377.1
 Shisa7

shisa homolog 7 (Xenopus laevis)

chr2_-_79908428 2.967 ENSMUST00000102652.3
ENSMUST00000102651.3
 Pde1a

phosphodiesterase 1A, calmodulin-dependent

chr2_+_65620829 2.934 ENSMUST00000028377.7
 Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr1_-_158814469 2.864 ENSMUST00000161589.2
 Pappa2
pappalysin 2
chr13_-_110280103 2.816 ENSMUST00000167824.1
 Rab3c
RAB3C, member RAS oncogene family
chr15_+_92597104 2.789 ENSMUST00000035399.8
 Pdzrn4
PDZ domain containing RING finger 4
chr6_-_59024470 2.777 ENSMUST00000089860.5
 Fam13a
family with sequence similarity 13, member A
chr10_-_33624587 2.624 ENSMUST00000160299.1
ENSMUST00000019920.6
 Clvs2

clavesin 2

chr18_+_67133713 2.524 ENSMUST00000076605.7
 Gnal
guanine nucleotide binding protein, alpha stimulating, olfactory type
chr6_-_136875794 2.520 ENSMUST00000032342.1
 Mgp
matrix Gla protein
chr15_+_4375462 2.459 ENSMUST00000061925.4
 Plcxd3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr7_-_103813913 2.391 ENSMUST00000098192.3
 Hbb-bt
hemoglobin, beta adult t chain
chr2_+_68104671 2.299 ENSMUST00000042456.3
 B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr14_-_93888732 2.286 ENSMUST00000068992.2
 Pcdh9
protocadherin 9
chrX_+_163911401 2.240 ENSMUST00000140845.1
 Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr19_+_44992127 2.234 ENSMUST00000179305.1
 Sema4g
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr12_+_52699297 2.231 ENSMUST00000095737.3
 Akap6
A kinase (PRKA) anchor protein 6

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 110 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 7.0 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.3 4.6 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 3.9 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 3.6 GO:0048813 dendrite morphogenesis(GO:0048813)
0.2 3.5 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.2 3.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 3.4 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.2 3.2 GO:0070842 aggresome assembly(GO:0070842)
0.2 2.7 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.3 2.6 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.2 2.6 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 2.6 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 2.6 GO:0060612 adipose tissue development(GO:0060612)
0.0 2.6 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.4 2.5 GO:0009405 pathogenesis(GO:0009405)
0.0 2.5 GO:0019882 antigen processing and presentation(GO:0019882)
0.6 2.2 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 2.2 GO:0050919 negative chemotaxis(GO:0050919)
0.2 2.0 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 2.0 GO:0030500 regulation of bone mineralization(GO:0030500)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 53 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.9 GO:0000139 Golgi membrane(GO:0000139)
0.0 6.3 GO:0043204 perikaryon(GO:0043204)
0.0 5.9 GO:0014069 postsynaptic density(GO:0014069)
0.0 5.3 GO:0005802 trans-Golgi network(GO:0005802)
0.4 3.9 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.2 3.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 3.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 3.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 2.8 GO:0008021 synaptic vesicle(GO:0008021)
0.1 2.6 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 2.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.6 2.4 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 2.2 GO:0030117 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.0 2.0 GO:0042641 actomyosin(GO:0042641)
0.2 1.8 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 1.8 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 1.6 GO:1902711 GABA-A receptor complex(GO:1902711)
0.3 1.5 GO:0044316 cone cell pedicle(GO:0044316)
0.1 1.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 1.5 GO:0030424 axon(GO:0030424)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 84 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.8 7.0 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.7 4.6 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.5 3.9 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 3.5 GO:0031489 myosin V binding(GO:0031489)
0.0 3.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 3.1 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 3.0 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 3.0 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.3 2.6 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 2.6 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 2.5 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.6 2.4 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.2 2.2 GO:0043495 protein anchor(GO:0043495)
0.1 2.0 GO:0050699 WW domain binding(GO:0050699)
0.2 1.8 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.4 1.5 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.4 1.5 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 1.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 1.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 1.5 GO:0030552 cAMP binding(GO:0030552)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.8 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 4.2 PID_LKB1_PATHWAY LKB1 signaling events
0.0 3.0 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.7 PID_ATR_PATHWAY ATR signaling pathway
0.1 2.5 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.1 2.0 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.0 1.7 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.6 PID_CXCR3_PATHWAY CXCR3-mediated signaling events
0.0 1.5 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 1.5 PID_CDC42_PATHWAY CDC42 signaling events
0.0 1.1 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 1.0 PID_ALK1_PATHWAY ALK1 signaling events
0.0 0.9 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 0.8 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 0.8 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.0 0.8 ST_INTEGRIN_SIGNALING_PATHWAY Integrin Signaling Pathway
0.1 0.6 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.6 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 0.5 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 0.5 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 4.6 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.1 3.1 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.2 2.9 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.6 2.8 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 2.8 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 2.6 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.2 2.2 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.7 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 1.6 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.1 1.5 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 1.5 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.1 1.4 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.2 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.0 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1 0.9 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.1 0.9 REACTOME_SIGNALING_BY_NOTCH4 Genes involved in Signaling by NOTCH4
0.0 0.8 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.8 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.6 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.5 REACTOME_PLC_BETA_MEDIATED_EVENTS Genes involved in PLC beta mediated events