Motif ID: Foxg1

Z-value: 0.399


Transcription factors associated with Foxg1:

Gene SymbolEntrez IDGene Name
Foxg1 ENSMUSG00000020950.9 Foxg1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxg1mm10_v2_chr12_+_49382791_49382883-0.411.7e-03Click!


Activity profile for motif Foxg1.

activity profile for motif Foxg1


Sorted Z-values histogram for motif Foxg1

Sorted Z-values for motif Foxg1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxg1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 48 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_-_120476469 6.825 ENSMUST00000072777.7
ENSMUST00000159699.1
 Hmga2

high mobility group AT-hook 2

chr4_+_154960915 2.494 ENSMUST00000049621.6
 Hes5
hairy and enhancer of split 5 (Drosophila)
chr2_-_57124003 2.449 ENSMUST00000112629.1
 Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr18_-_34007206 2.316 ENSMUST00000025234.5
 Epb4.1l4a
erythrocyte protein band 4.1-like 4a
chr9_+_91378636 2.189 ENSMUST00000066384.5
 Zic4
zinc finger protein of the cerebellum 4
chr12_-_10900296 1.680 ENSMUST00000085735.2
 Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chr15_-_85581809 1.653 ENSMUST00000023015.7
 Wnt7b
wingless-related MMTV integration site 7B
chr10_+_22158566 1.652 ENSMUST00000181645.1
ENSMUST00000105522.2
 Raet1e
H60b
retinoic acid early transcript 1E
histocompatibility 60b
chr13_-_3918157 1.504 ENSMUST00000091853.4
 Net1
neuroepithelial cell transforming gene 1
chr1_-_84284423 1.476 ENSMUST00000176720.1
 Pid1
phosphotyrosine interaction domain containing 1
chr11_-_28583995 0.965 ENSMUST00000146385.2
 Ccdc85a
coiled-coil domain containing 85A
chr7_-_115824699 0.921 ENSMUST00000169129.1
 Sox6
SRY-box containing gene 6
chr1_-_72874877 0.883 ENSMUST00000027377.8
 Igfbp5
insulin-like growth factor binding protein 5
chr13_+_34162953 0.642 ENSMUST00000124996.1
ENSMUST00000147632.1
 Psmg4

proteasome (prosome, macropain) assembly chaperone 4

chr2_-_154558834 0.603 ENSMUST00000109716.2
ENSMUST00000000895.6
ENSMUST00000125793.1
 Necab3


N-terminal EF-hand calcium binding protein 3


chr18_+_11839220 0.511 ENSMUST00000171109.1
ENSMUST00000046948.8
 Cables1

CDK5 and Abl enzyme substrate 1

chr4_-_108833544 0.498 ENSMUST00000102740.1
ENSMUST00000102741.1
 Btf3l4

basic transcription factor 3-like 4

chr9_-_60649793 0.493 ENSMUST00000053171.7
 Lrrc49
leucine rich repeat containing 49
chr11_-_89538556 0.465 ENSMUST00000169201.1
 Ankfn1
ankyrin-repeat and fibronectin type III domain containing 1
chr5_-_142906702 0.455 ENSMUST00000167721.1
ENSMUST00000163829.1
ENSMUST00000100497.4
 Actb


actin, beta



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 6.8 GO:0060613 fat pad development(GO:0060613)
0.6 2.5 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
0.6 2.4 GO:0051866 general adaptation syndrome(GO:0051866)
0.6 1.7 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.1 1.7 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.4 1.5 GO:0070346 positive regulation of fat cell proliferation(GO:0070346) negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.1 1.5 GO:0051451 myoblast migration(GO:0051451)
0.1 0.9 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.9 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.1 0.6 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.6 GO:0043248 proteasome assembly(GO:0043248)
0.2 0.5 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.1 0.5 GO:0050957 equilibrioception(GO:0050957)
0.1 0.4 GO:0071335 hair follicle cell proliferation(GO:0071335)
0.1 0.3 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 0.3 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.3 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.1 0.2 GO:0046898 response to cycloheximide(GO:0046898)
0.1 0.2 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.0 0.2 GO:0071896 protein localization to adherens junction(GO:0071896)

Gene overrepresentation in cellular_component category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 6.8 GO:0000785 chromatin(GO:0000785)
0.4 1.7 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.2 0.9 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 0.6 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.5 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.4 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)

Gene overrepresentation in molecular_function category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 6.8 GO:0003680 AT DNA binding(GO:0003680)
0.1 2.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.4 1.7 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.2 1.7 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 1.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.9 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.2 0.5 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.1 0.4 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 0.4 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1 0.3 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 0.2 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)

Gene overrepresentation in C2:CP category:

Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.5 PID_CDC42_PATHWAY CDC42 signaling events
0.1 1.7 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 1.5 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.9 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.5 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 2.4 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 2.0 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 1.7 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.5 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.1 0.9 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.5 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.4 REACTOME_MICRORNA_MIRNA_BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.2 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.2 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC