Motif ID: Foxg1

Z-value: 0.399


Transcription factors associated with Foxg1:

Gene SymbolEntrez IDGene Name
Foxg1 ENSMUSG00000020950.9 Foxg1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxg1mm10_v2_chr12_+_49382791_49382883-0.411.7e-03Click!


Activity profile for motif Foxg1.

activity profile for motif Foxg1


Sorted Z-values histogram for motif Foxg1

Sorted Z-values for motif Foxg1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxg1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_120476469 6.825 ENSMUST00000072777.7
ENSMUST00000159699.1
 Hmga2

high mobility group AT-hook 2

chr4_+_154960915 2.494 ENSMUST00000049621.6
 Hes5
hairy and enhancer of split 5 (Drosophila)
chr2_-_57124003 2.449 ENSMUST00000112629.1
 Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr18_-_34007206 2.316 ENSMUST00000025234.5
 Epb4.1l4a
erythrocyte protein band 4.1-like 4a
chr9_+_91378636 2.189 ENSMUST00000066384.5
 Zic4
zinc finger protein of the cerebellum 4
chr12_-_10900296 1.680 ENSMUST00000085735.2
 Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chr15_-_85581809 1.653 ENSMUST00000023015.7
 Wnt7b
wingless-related MMTV integration site 7B
chr10_+_22158566 1.652 ENSMUST00000181645.1
ENSMUST00000105522.2
 Raet1e
H60b
retinoic acid early transcript 1E
histocompatibility 60b
chr13_-_3918157 1.504 ENSMUST00000091853.4
 Net1
neuroepithelial cell transforming gene 1
chr1_-_84284423 1.476 ENSMUST00000176720.1
 Pid1
phosphotyrosine interaction domain containing 1
chr11_-_28583995 0.965 ENSMUST00000146385.2
 Ccdc85a
coiled-coil domain containing 85A
chr7_-_115824699 0.921 ENSMUST00000169129.1
 Sox6
SRY-box containing gene 6
chr1_-_72874877 0.883 ENSMUST00000027377.8
 Igfbp5
insulin-like growth factor binding protein 5
chr13_+_34162953 0.642 ENSMUST00000124996.1
ENSMUST00000147632.1
 Psmg4

proteasome (prosome, macropain) assembly chaperone 4

chr2_-_154558834 0.603 ENSMUST00000109716.2
ENSMUST00000000895.6
ENSMUST00000125793.1
 Necab3


N-terminal EF-hand calcium binding protein 3


chr18_+_11839220 0.511 ENSMUST00000171109.1
ENSMUST00000046948.8
 Cables1

CDK5 and Abl enzyme substrate 1

chr4_-_108833544 0.498 ENSMUST00000102740.1
ENSMUST00000102741.1
 Btf3l4

basic transcription factor 3-like 4

chr9_-_60649793 0.493 ENSMUST00000053171.7
 Lrrc49
leucine rich repeat containing 49
chr11_-_89538556 0.465 ENSMUST00000169201.1
 Ankfn1
ankyrin-repeat and fibronectin type III domain containing 1
chr5_-_142906702 0.455 ENSMUST00000167721.1
ENSMUST00000163829.1
ENSMUST00000100497.4
 Actb


actin, beta


chr9_+_64121501 0.433 ENSMUST00000118215.1
 Lctl
lactase-like
chr12_-_104751900 0.408 ENSMUST00000041987.6
 Dicer1
dicer 1, ribonuclease type III
chr6_-_72345144 0.393 ENSMUST00000070345.3
 Usp39
ubiquitin specific peptidase 39
chr11_+_72607221 0.382 ENSMUST00000021148.6
ENSMUST00000138247.1
 Ube2g1

ubiquitin-conjugating enzyme E2G 1

chr6_-_12109583 0.372 ENSMUST00000080891.5
 Gm6578
predicted gene 6578
chr15_-_95528702 0.348 ENSMUST00000166170.1
 Nell2
NEL-like 2
chr2_+_174330006 0.346 ENSMUST00000109085.1
ENSMUST00000109087.1
ENSMUST00000109084.1
 Gnas


GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus


chr2_-_152830615 0.296 ENSMUST00000146380.1
ENSMUST00000134902.1
ENSMUST00000134357.1
ENSMUST00000109820.3
 Bcl2l1



BCL2-like 1



chr5_-_134314678 0.292 ENSMUST00000174354.1
ENSMUST00000174155.1
ENSMUST00000174513.1
ENSMUST00000174772.1
ENSMUST00000173341.1
ENSMUST00000111261.4
ENSMUST00000082057.3
ENSMUST00000059042.7
 Gtf2i







general transcription factor II I







chr12_+_112999964 0.266 ENSMUST00000180971.1
 9230104M06Rik
RIKEN cDNA 9230104M06 gene
chr16_-_90284300 0.245 ENSMUST00000163419.1
 Scaf4
SR-related CTD-associated factor 4
chr2_-_164389095 0.244 ENSMUST00000167427.1
 Slpi
secretory leukocyte peptidase inhibitor
chr12_-_59011996 0.241 ENSMUST00000021375.5
 Sec23a
SEC23A (S. cerevisiae)
chr3_-_50443603 0.241 ENSMUST00000029297.4
 Slc7a11
solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
chr16_-_90284412 0.229 ENSMUST00000039280.7
 Scaf4
SR-related CTD-associated factor 4
chr13_-_71963713 0.210 ENSMUST00000077337.8
 Irx1
Iroquois related homeobox 1 (Drosophila)
chr14_-_24245913 0.168 ENSMUST00000073687.6
ENSMUST00000090398.4
 Dlg5

discs, large homolog 5 (Drosophila)

chr4_-_108833608 0.161 ENSMUST00000102742.4
 Btf3l4
basic transcription factor 3-like 4
chr19_+_11770415 0.153 ENSMUST00000167199.1
 Mrpl16
mitochondrial ribosomal protein L16
chr17_+_80944611 0.139 ENSMUST00000025092.4
 Tmem178
transmembrane protein 178
chr6_-_129717132 0.110 ENSMUST00000088046.1
 Klri1
killer cell lectin-like receptor family I member 1
chr5_-_121191365 0.092 ENSMUST00000100770.2
ENSMUST00000054547.7
 Ptpn11

protein tyrosine phosphatase, non-receptor type 11

chr9_+_106170918 0.087 ENSMUST00000020490.5
 Wdr82
WD repeat domain containing 82
chr8_-_33641940 0.048 ENSMUST00000095349.4
 Ubxn8
UBX domain protein 8
chr1_-_180813534 0.033 ENSMUST00000159789.1
ENSMUST00000081026.4
 H3f3a

H3 histone, family 3A

chr5_+_34369909 0.031 ENSMUST00000180376.1
 Fam193a
family with sequence similarity 193, member A
chr4_+_141793612 0.027 ENSMUST00000097805.4
ENSMUST00000030747.4
ENSMUST00000153094.1
 Casp9


caspase 9


chr19_-_4615453 0.009 ENSMUST00000053597.2
 Lrfn4
leucine rich repeat and fibronectin type III domain containing 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 6.8 GO:0060613 fat pad development(GO:0060613)
0.6 2.5 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
0.6 2.4 GO:0051866 general adaptation syndrome(GO:0051866)
0.6 1.7 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.4 1.5 GO:0070346 positive regulation of fat cell proliferation(GO:0070346) negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.2 0.5 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.1 0.4 GO:0071335 hair follicle cell proliferation(GO:0071335)
0.1 0.9 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 0.9 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.1 1.5 GO:0051451 myoblast migration(GO:0051451)
0.1 0.3 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 0.6 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1 1.7 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.1 0.3 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 0.2 GO:0046898 response to cycloheximide(GO:0046898)
0.1 0.2 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.1 0.5 GO:0050957 equilibrioception(GO:0050957)
0.0 0.6 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.2 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.1 GO:2000850 negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.0 0.3 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.2 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0019731 antibacterial humoral response(GO:0019731)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.2 0.9 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 0.6 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.4 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.5 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 6.8 GO:0000785 chromatin(GO:0000785)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.8 GO:0003680 AT DNA binding(GO:0003680)
0.4 1.7 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.2 1.7 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.2 0.5 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.1 0.9 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.4 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 0.4 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1 2.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 1.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.2 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.1 0.3 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 2.5 PID_CDC42_PATHWAY CDC42 signaling events
0.0 1.5 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.9 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 0.9 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 2.4 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 2.5 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 2.0 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.5 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.4 REACTOME_MICRORNA_MIRNA_BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.2 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.5 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.2 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC