Motif ID: Foxm1

Z-value: 0.699


Transcription factors associated with Foxm1:

Gene SymbolEntrez IDGene Name
Foxm1 ENSMUSG00000001517.8 Foxm1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxm1mm10_v2_chr6_+_128362919_128363058-0.293.5e-02Click!


Activity profile for motif Foxm1.

activity profile for motif Foxm1


Sorted Z-values histogram for motif Foxm1

Sorted Z-values for motif Foxm1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxm1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 153 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_65845833 5.293 ENSMUST00000053910.3
 Csrnp3
cysteine-serine-rich nuclear protein 3
chr2_+_65845767 4.333 ENSMUST00000122912.1
 Csrnp3
cysteine-serine-rich nuclear protein 3
chr1_-_79440039 3.549 ENSMUST00000049972.4
 Scg2
secretogranin II
chr15_+_98167806 3.425 ENSMUST00000031914.4
 AI836003
expressed sequence AI836003
chr19_+_25672408 3.221 ENSMUST00000053068.5
 Dmrt2
doublesex and mab-3 related transcription factor 2
chrX_+_164373363 2.827 ENSMUST00000033751.7
 Figf
c-fos induced growth factor
chr18_+_36952621 2.707 ENSMUST00000115661.2
 Pcdha2
protocadherin alpha 2
chr18_+_67133713 2.500 ENSMUST00000076605.7
 Gnal
guanine nucleotide binding protein, alpha stimulating, olfactory type
chr4_-_36136463 2.280 ENSMUST00000098151.2
 Lingo2
leucine rich repeat and Ig domain containing 2
chr8_+_34807287 2.145 ENSMUST00000033930.4
 Dusp4
dual specificity phosphatase 4
chr1_-_138842429 2.098 ENSMUST00000112026.2
ENSMUST00000019374.7
 Lhx9

LIM homeobox protein 9

chrX_-_141725181 2.066 ENSMUST00000067841.7
 Irs4
insulin receptor substrate 4
chr8_+_58912257 1.935 ENSMUST00000160055.1
 BC030500
cDNA sequence BC030500
chr6_-_59024340 1.884 ENSMUST00000173193.1
 Fam13a
family with sequence similarity 13, member A
chr3_+_134828993 1.876 ENSMUST00000029822.4
 Tacr3
tachykinin receptor 3
chr9_-_75597643 1.836 ENSMUST00000164100.1
 Tmod2
tropomodulin 2
chr18_-_62741387 1.791 ENSMUST00000097557.3
 Spink13
serine peptidase inhibitor, Kazal type 13
chr2_+_68117713 1.585 ENSMUST00000112346.2
 B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr7_-_19921139 1.546 ENSMUST00000043517.7
 Pvr
poliovirus receptor
chr10_+_112928501 1.419 ENSMUST00000180464.1
 Gm26596
predicted gene, 26596

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 67 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 9.6 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.7 3.5 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.8 3.2 GO:0061055 myotome development(GO:0061055)
0.3 2.6 GO:0071420 cellular response to histamine(GO:0071420)
0.4 2.5 GO:0009405 pathogenesis(GO:0009405)
0.0 2.3 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 2.3 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.4 2.1 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 2.1 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.2 1.9 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.4 1.8 GO:0060467 negative regulation of fertilization(GO:0060467)
0.3 1.8 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 1.8 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation(GO:0050731)
0.2 1.6 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.5 1.5 GO:0002423 natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.2 1.3 GO:0000733 DNA strand renaturation(GO:0000733)
0.1 1.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 1.1 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 1.1 GO:0007416 synapse assembly(GO:0007416)
0.2 1.0 GO:0007258 JUN phosphorylation(GO:0007258)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 3.5 GO:0031045 dense core granule(GO:0031045)
0.1 3.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 2.6 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 2.3 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.9 GO:0032590 dendrite membrane(GO:0032590)
0.0 1.9 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 1.8 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 1.2 GO:0016514 SWI/SNF complex(GO:0016514)
0.2 1.0 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 1.0 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 1.0 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.0 GO:0043204 perikaryon(GO:0043204)
0.0 1.0 GO:0005930 axoneme(GO:0005930)
0.0 0.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 0.8 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.8 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.7 GO:0002177 manchette(GO:0002177)
0.0 0.7 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.7 GO:0032279 asymmetric synapse(GO:0032279)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 52 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 9.9 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.2 3.5 GO:0042056 chemoattractant activity(GO:0042056)
0.1 2.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 2.5 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 2.3 GO:0005158 insulin receptor binding(GO:0005158)
0.7 2.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 1.9 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.2 1.8 GO:0005523 tropomyosin binding(GO:0005523)
0.0 1.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.4 1.6 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 1.5 GO:0001618 virus receptor activity(GO:0001618)
0.2 1.3 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 1.2 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 1.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.3 1.0 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 1.0 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 1.0 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.9 GO:0050699 WW domain binding(GO:0050699)
0.1 0.8 GO:0051434 BH3 domain binding(GO:0051434)

Gene overrepresentation in C2:CP category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.2 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
0.2 2.8 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.1 2.5 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 2.3 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.0 1.8 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.5 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 1.0 PID_RHOA_REG_PATHWAY Regulation of RhoA activity
0.0 0.8 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 0.7 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 0.6 PID_TCPTP_PATHWAY Signaling events mediated by TCPTP
0.0 0.4 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 3.2 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 2.9 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.2 2.8 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.2 2.6 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.1 2.1 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.0 1.8 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.5 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 1.2 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 1.0 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 0.8 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.8 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.7 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.7 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.0 0.7 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 0.6 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.1 0.6 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.6 REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.1 0.5 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.5 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling