Motif ID: Foxp2_Foxp3
Z-value: 0.701
Transcription factors associated with Foxp2_Foxp3:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Foxp2 | ENSMUSG00000029563.10 | Foxp2 |
| Foxp3 | ENSMUSG00000039521.6 | Foxp3 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Foxp2 | mm10_v2_chr6_+_14901344_14901364 | -0.24 | 7.7e-02 | Click! |
| Foxp3 | mm10_v2_chrX_+_7579666_7579693 | -0.12 | 3.9e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.2 | 6.5 | GO:0032915 | positive regulation of transforming growth factor beta2 production(GO:0032915) |
| 1.6 | 18.0 | GO:0042572 | retinol metabolic process(GO:0042572) |
| 1.4 | 4.2 | GO:0014877 | response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
| 1.4 | 4.1 | GO:0043379 | rRNA export from nucleus(GO:0006407) memory T cell differentiation(GO:0043379) response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) |
| 1.1 | 8.0 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
| 1.1 | 3.3 | GO:0043988 | histone H3-S28 phosphorylation(GO:0043988) |
| 1.1 | 4.2 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
| 1.0 | 3.0 | GO:0099547 | regulation of translation at synapse, modulating synaptic transmission(GO:0099547) regulation of translation at postsynapse, modulating synaptic transmission(GO:0099578) positive regulation of intracellular transport of viral material(GO:1901254) |
| 1.0 | 4.0 | GO:0002069 | columnar/cuboidal epithelial cell maturation(GO:0002069) |
| 0.8 | 2.4 | GO:0002159 | desmosome assembly(GO:0002159) |
| 0.8 | 2.3 | GO:0002182 | cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248) |
| 0.8 | 2.3 | GO:0090004 | positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004) |
| 0.7 | 13.8 | GO:0002495 | antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) |
| 0.7 | 3.4 | GO:0097167 | circadian regulation of translation(GO:0097167) |
| 0.6 | 8.2 | GO:0016191 | synaptic vesicle uncoating(GO:0016191) |
| 0.6 | 5.6 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.6 | 4.7 | GO:0060137 | maternal process involved in parturition(GO:0060137) |
| 0.6 | 8.8 | GO:1902260 | negative regulation of delayed rectifier potassium channel activity(GO:1902260) |
| 0.6 | 1.7 | GO:2000312 | regulation of kainate selective glutamate receptor activity(GO:2000312) |
| 0.5 | 7.1 | GO:0070842 | aggresome assembly(GO:0070842) |
| 0.5 | 2.7 | GO:0046684 | response to pyrethroid(GO:0046684) |
| 0.5 | 1.6 | GO:0016998 | cell wall macromolecule catabolic process(GO:0016998) |
| 0.5 | 3.2 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
| 0.5 | 2.1 | GO:0070305 | response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321) |
| 0.5 | 3.6 | GO:0033227 | dsRNA transport(GO:0033227) |
| 0.5 | 2.0 | GO:1900740 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) |
| 0.5 | 2.5 | GO:2000481 | positive regulation of cAMP-dependent protein kinase activity(GO:2000481) |
| 0.5 | 5.6 | GO:0097421 | liver regeneration(GO:0097421) |
| 0.5 | 3.3 | GO:0035826 | rubidium ion transport(GO:0035826) cellular hypotonic response(GO:0071476) |
| 0.5 | 1.4 | GO:0090327 | negative regulation of locomotion involved in locomotory behavior(GO:0090327) |
| 0.5 | 5.1 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
| 0.5 | 1.4 | GO:0060060 | post-embryonic retina morphogenesis in camera-type eye(GO:0060060) |
| 0.4 | 2.2 | GO:0050847 | progesterone receptor signaling pathway(GO:0050847) |
| 0.4 | 1.7 | GO:0055099 | response to high density lipoprotein particle(GO:0055099) platelet dense granule organization(GO:0060155) |
| 0.4 | 3.8 | GO:0035887 | aortic smooth muscle cell differentiation(GO:0035887) |
| 0.4 | 4.6 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
| 0.4 | 1.2 | GO:0050925 | negative regulation of negative chemotaxis(GO:0050925) |
| 0.4 | 1.6 | GO:0035470 | positive regulation of vascular wound healing(GO:0035470) |
| 0.4 | 1.2 | GO:1903538 | meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538) |
| 0.4 | 2.3 | GO:0071630 | nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630) |
| 0.4 | 6.1 | GO:2000096 | positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
| 0.4 | 4.1 | GO:0042118 | endothelial cell activation(GO:0042118) |
| 0.4 | 1.1 | GO:0032650 | regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) interleukin-1 alpha secretion(GO:0050703) regulation of bleb assembly(GO:1904170) |
| 0.3 | 1.0 | GO:0045575 | basophil activation involved in immune response(GO:0002276) basophil activation(GO:0045575) |
| 0.3 | 1.7 | GO:2000301 | negative regulation of synaptic vesicle exocytosis(GO:2000301) |
| 0.3 | 1.0 | GO:0035526 | retrograde transport, plasma membrane to Golgi(GO:0035526) |
| 0.3 | 0.9 | GO:0000389 | mRNA 3'-splice site recognition(GO:0000389) |
| 0.3 | 1.9 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.3 | 1.2 | GO:0035461 | vitamin transmembrane transport(GO:0035461) |
| 0.3 | 1.8 | GO:0031666 | positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666) |
| 0.3 | 0.9 | GO:0090425 | hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979) |
| 0.3 | 1.5 | GO:0035720 | intraciliary anterograde transport(GO:0035720) |
| 0.3 | 0.9 | GO:0070343 | white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350) |
| 0.3 | 0.8 | GO:0019482 | beta-alanine metabolic process(GO:0019482) |
| 0.3 | 0.8 | GO:0048014 | Tie signaling pathway(GO:0048014) |
| 0.3 | 0.8 | GO:0071963 | establishment or maintenance of cell polarity regulating cell shape(GO:0071963) |
| 0.3 | 0.8 | GO:0030827 | negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283) |
| 0.3 | 1.1 | GO:1903028 | regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028) |
| 0.3 | 0.8 | GO:1901894 | regulation of calcium-transporting ATPase activity(GO:1901894) |
| 0.3 | 0.8 | GO:0017055 | negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055) |
| 0.3 | 2.3 | GO:0019227 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
| 0.2 | 1.9 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
| 0.2 | 1.0 | GO:0046368 | GDP-L-fucose metabolic process(GO:0046368) |
| 0.2 | 8.8 | GO:0010614 | negative regulation of cardiac muscle hypertrophy(GO:0010614) |
| 0.2 | 1.9 | GO:0060665 | regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665) |
| 0.2 | 3.5 | GO:0021527 | spinal cord association neuron differentiation(GO:0021527) |
| 0.2 | 0.7 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
| 0.2 | 1.2 | GO:0042636 | negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) regulation of follicle-stimulating hormone secretion(GO:0046880) follicle-stimulating hormone secretion(GO:0046884) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279) |
| 0.2 | 1.4 | GO:0007144 | female meiosis I(GO:0007144) |
| 0.2 | 1.9 | GO:0002327 | immature B cell differentiation(GO:0002327) |
| 0.2 | 1.4 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
| 0.2 | 4.0 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclase activity(GO:0031280) |
| 0.2 | 1.8 | GO:0006390 | transcription from mitochondrial promoter(GO:0006390) |
| 0.2 | 0.9 | GO:0051088 | PMA-inducible membrane protein ectodomain proteolysis(GO:0051088) |
| 0.2 | 1.7 | GO:0048752 | semicircular canal morphogenesis(GO:0048752) |
| 0.2 | 2.4 | GO:0071455 | cellular response to hyperoxia(GO:0071455) cellular response to nitric oxide(GO:0071732) |
| 0.2 | 1.1 | GO:0044314 | protein K27-linked ubiquitination(GO:0044314) |
| 0.2 | 1.1 | GO:1901668 | regulation of superoxide dismutase activity(GO:1901668) |
| 0.2 | 1.1 | GO:2001015 | negative regulation of skeletal muscle cell differentiation(GO:2001015) |
| 0.2 | 1.1 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
| 0.2 | 3.2 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
| 0.2 | 2.0 | GO:0034551 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033) |
| 0.2 | 1.0 | GO:1902951 | negative regulation of dendritic spine maintenance(GO:1902951) |
| 0.2 | 1.0 | GO:0002317 | plasma cell differentiation(GO:0002317) |
| 0.2 | 1.1 | GO:0050861 | positive regulation of B cell receptor signaling pathway(GO:0050861) |
| 0.2 | 1.2 | GO:0000414 | regulation of histone H3-K36 methylation(GO:0000414) |
| 0.2 | 0.7 | GO:0052151 | positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139) apoptotic process involved in embryonic digit morphogenesis(GO:1902263) |
| 0.2 | 0.9 | GO:0008655 | pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097) |
| 0.2 | 1.0 | GO:0042276 | error-prone translesion synthesis(GO:0042276) |
| 0.2 | 1.3 | GO:0098707 | ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707) |
| 0.2 | 0.5 | GO:0044028 | DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029) |
| 0.2 | 0.7 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
| 0.2 | 3.8 | GO:0008090 | retrograde axonal transport(GO:0008090) |
| 0.2 | 0.7 | GO:0008355 | olfactory learning(GO:0008355) |
| 0.2 | 0.8 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
| 0.2 | 0.8 | GO:1990573 | potassium ion import across plasma membrane(GO:1990573) |
| 0.2 | 0.6 | GO:0072137 | condensed mesenchymal cell proliferation(GO:0072137) |
| 0.2 | 2.0 | GO:2001014 | regulation of skeletal muscle cell differentiation(GO:2001014) |
| 0.1 | 0.7 | GO:0034638 | phosphatidylcholine catabolic process(GO:0034638) |
| 0.1 | 2.1 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
| 0.1 | 1.3 | GO:0090166 | Golgi disassembly(GO:0090166) |
| 0.1 | 5.9 | GO:0007026 | negative regulation of microtubule depolymerization(GO:0007026) |
| 0.1 | 4.9 | GO:0051491 | positive regulation of filopodium assembly(GO:0051491) |
| 0.1 | 0.9 | GO:0018243 | protein O-linked glycosylation via threonine(GO:0018243) |
| 0.1 | 0.9 | GO:0060267 | positive regulation of respiratory burst(GO:0060267) |
| 0.1 | 1.2 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.1 | 1.4 | GO:0060136 | embryonic process involved in female pregnancy(GO:0060136) |
| 0.1 | 0.6 | GO:0021993 | initiation of neural tube closure(GO:0021993) |
| 0.1 | 1.7 | GO:0035988 | chondrocyte proliferation(GO:0035988) |
| 0.1 | 2.2 | GO:0006054 | N-acetylneuraminate metabolic process(GO:0006054) |
| 0.1 | 1.9 | GO:0009083 | branched-chain amino acid catabolic process(GO:0009083) |
| 0.1 | 2.3 | GO:0043552 | positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552) |
| 0.1 | 0.6 | GO:1901165 | positive regulation of trophoblast cell migration(GO:1901165) |
| 0.1 | 1.9 | GO:0030953 | astral microtubule organization(GO:0030953) |
| 0.1 | 1.0 | GO:0043589 | skin morphogenesis(GO:0043589) |
| 0.1 | 0.6 | GO:0072530 | purine-containing compound transmembrane transport(GO:0072530) |
| 0.1 | 0.7 | GO:1903056 | melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056) |
| 0.1 | 0.5 | GO:1903378 | positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378) |
| 0.1 | 1.5 | GO:2001256 | regulation of store-operated calcium entry(GO:2001256) |
| 0.1 | 1.6 | GO:0015809 | arginine transport(GO:0015809) |
| 0.1 | 2.1 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.1 | 1.9 | GO:0003215 | cardiac right ventricle morphogenesis(GO:0003215) |
| 0.1 | 2.2 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
| 0.1 | 0.9 | GO:0034776 | response to histamine(GO:0034776) cellular response to histamine(GO:0071420) |
| 0.1 | 4.0 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.1 | 0.7 | GO:0030382 | sperm mitochondrion organization(GO:0030382) |
| 0.1 | 0.4 | GO:2000774 | positive regulation of cellular senescence(GO:2000774) |
| 0.1 | 0.4 | GO:0002188 | translation reinitiation(GO:0002188) |
| 0.1 | 0.3 | GO:0030473 | nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473) nuclear migration along microfilament(GO:0031022) |
| 0.1 | 2.7 | GO:0095500 | acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145) |
| 0.1 | 1.1 | GO:0031987 | locomotion involved in locomotory behavior(GO:0031987) |
| 0.1 | 0.4 | GO:0010735 | positive regulation of transcription via serum response element binding(GO:0010735) |
| 0.1 | 0.1 | GO:0060681 | branch elongation involved in ureteric bud branching(GO:0060681) |
| 0.1 | 0.3 | GO:1903244 | positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) regulation of connective tissue replacement(GO:1905203) |
| 0.1 | 0.3 | GO:0050904 | diapedesis(GO:0050904) |
| 0.1 | 3.8 | GO:0034605 | cellular response to heat(GO:0034605) |
| 0.1 | 0.9 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.1 | 0.2 | GO:1900623 | regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625) |
| 0.1 | 0.5 | GO:0061343 | cell adhesion involved in heart morphogenesis(GO:0061343) |
| 0.1 | 0.2 | GO:0046340 | diacylglycerol catabolic process(GO:0046340) |
| 0.1 | 0.1 | GO:0060913 | cardiac cell fate determination(GO:0060913) regulation of cardiac cell fate specification(GO:2000043) |
| 0.1 | 0.1 | GO:0072488 | ammonium transmembrane transport(GO:0072488) |
| 0.1 | 1.7 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.1 | 0.7 | GO:0030225 | macrophage differentiation(GO:0030225) |
| 0.1 | 1.3 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
| 0.1 | 0.2 | GO:0015886 | heme transport(GO:0015886) |
| 0.1 | 3.2 | GO:0046326 | positive regulation of glucose import(GO:0046326) |
| 0.1 | 0.5 | GO:0061002 | negative regulation of dendritic spine morphogenesis(GO:0061002) |
| 0.1 | 0.5 | GO:2000270 | negative regulation of fibroblast apoptotic process(GO:2000270) |
| 0.1 | 0.2 | GO:0060762 | regulation of branching involved in mammary gland duct morphogenesis(GO:0060762) |
| 0.1 | 1.3 | GO:0019835 | cytolysis(GO:0019835) |
| 0.1 | 0.3 | GO:0090292 | nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292) |
| 0.1 | 0.5 | GO:0015868 | purine ribonucleotide transport(GO:0015868) |
| 0.1 | 0.8 | GO:0031507 | heterochromatin assembly(GO:0031507) |
| 0.1 | 0.8 | GO:0001553 | luteinization(GO:0001553) |
| 0.1 | 5.1 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.1 | 1.1 | GO:0097094 | craniofacial suture morphogenesis(GO:0097094) |
| 0.1 | 0.4 | GO:0005513 | detection of calcium ion(GO:0005513) |
| 0.1 | 0.4 | GO:2000483 | negative regulation of interleukin-8 secretion(GO:2000483) |
| 0.1 | 0.1 | GO:0097155 | fasciculation of sensory neuron axon(GO:0097155) |
| 0.1 | 0.4 | GO:0032287 | peripheral nervous system myelin maintenance(GO:0032287) |
| 0.1 | 0.8 | GO:0032933 | response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501) |
| 0.1 | 0.4 | GO:0070294 | renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294) |
| 0.1 | 0.6 | GO:0045717 | negative regulation of fatty acid biosynthetic process(GO:0045717) |
| 0.1 | 0.4 | GO:0019532 | oxalate transport(GO:0019532) |
| 0.1 | 0.5 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) |
| 0.1 | 1.0 | GO:2000310 | regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310) |
| 0.1 | 0.8 | GO:0007097 | nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023) |
| 0.1 | 0.8 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 0.0 | 0.4 | GO:0010745 | negative regulation of macrophage derived foam cell differentiation(GO:0010745) |
| 0.0 | 0.6 | GO:0060213 | regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) |
| 0.0 | 0.6 | GO:0010216 | maintenance of DNA methylation(GO:0010216) |
| 0.0 | 0.6 | GO:0006953 | acute-phase response(GO:0006953) |
| 0.0 | 0.9 | GO:0045793 | positive regulation of cell size(GO:0045793) |
| 0.0 | 1.5 | GO:2000249 | regulation of actin cytoskeleton reorganization(GO:2000249) |
| 0.0 | 0.9 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 0.0 | 0.3 | GO:0048227 | plasma membrane to endosome transport(GO:0048227) |
| 0.0 | 0.1 | GO:0021972 | negative regulation of lamellipodium assembly(GO:0010593) cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) corticospinal neuron axon guidance(GO:0021966) corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260) |
| 0.0 | 0.8 | GO:0036342 | post-anal tail morphogenesis(GO:0036342) |
| 0.0 | 0.4 | GO:0061635 | regulation of protein complex stability(GO:0061635) |
| 0.0 | 0.4 | GO:2001197 | regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197) |
| 0.0 | 0.3 | GO:0046543 | development of secondary female sexual characteristics(GO:0046543) |
| 0.0 | 0.3 | GO:0033689 | negative regulation of osteoblast proliferation(GO:0033689) |
| 0.0 | 0.2 | GO:0042368 | negative regulation of vitamin D biosynthetic process(GO:0010957) vitamin D biosynthetic process(GO:0042368) negative regulation of vitamin metabolic process(GO:0046137) regulation of vitamin D biosynthetic process(GO:0060556) regulation of cell differentiation involved in embryonic placenta development(GO:0060800) Notch signaling involved in heart development(GO:0061314) |
| 0.0 | 1.0 | GO:0070536 | protein K63-linked deubiquitination(GO:0070536) |
| 0.0 | 0.2 | GO:0071787 | endoplasmic reticulum tubular network assembly(GO:0071787) |
| 0.0 | 0.4 | GO:0034390 | smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391) |
| 0.0 | 0.1 | GO:0071635 | negative regulation of transforming growth factor beta1 production(GO:0032911) negative regulation of transforming growth factor beta production(GO:0071635) dibasic protein processing(GO:0090472) |
| 0.0 | 0.1 | GO:0009597 | detection of virus(GO:0009597) |
| 0.0 | 0.5 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
| 0.0 | 0.9 | GO:0048025 | negative regulation of mRNA splicing, via spliceosome(GO:0048025) |
| 0.0 | 0.7 | GO:0002931 | response to ischemia(GO:0002931) |
| 0.0 | 0.4 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.0 | 0.2 | GO:0042126 | nitrate metabolic process(GO:0042126) |
| 0.0 | 0.8 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
| 0.0 | 0.1 | GO:1902310 | positive regulation of peptidyl-serine dephosphorylation(GO:1902310) |
| 0.0 | 0.5 | GO:0046324 | regulation of glucose import(GO:0046324) |
| 0.0 | 0.4 | GO:0007035 | vacuolar acidification(GO:0007035) |
| 0.0 | 2.1 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
| 0.0 | 0.4 | GO:0045947 | negative regulation of translational initiation(GO:0045947) |
| 0.0 | 0.1 | GO:0010920 | negative regulation of inositol phosphate biosynthetic process(GO:0010920) |
| 0.0 | 0.4 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
| 0.0 | 0.1 | GO:0071896 | protein localization to adherens junction(GO:0071896) |
| 0.0 | 1.2 | GO:0032456 | endocytic recycling(GO:0032456) |
| 0.0 | 0.2 | GO:0003214 | cardiac left ventricle morphogenesis(GO:0003214) |
| 0.0 | 0.8 | GO:0006471 | protein ADP-ribosylation(GO:0006471) |
| 0.0 | 0.3 | GO:0002755 | MyD88-dependent toll-like receptor signaling pathway(GO:0002755) |
| 0.0 | 1.2 | GO:0008542 | visual learning(GO:0008542) |
| 0.0 | 0.6 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.0 | 0.3 | GO:2000042 | negative regulation of double-strand break repair via homologous recombination(GO:2000042) |
| 0.0 | 3.3 | GO:0007416 | synapse assembly(GO:0007416) |
| 0.0 | 0.3 | GO:1901898 | negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898) |
| 0.0 | 0.1 | GO:0034238 | macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) |
| 0.0 | 0.2 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.0 | 0.9 | GO:0050919 | negative chemotaxis(GO:0050919) |
| 0.0 | 0.1 | GO:0090298 | negative regulation of mitochondrial DNA replication(GO:0090298) |
| 0.0 | 0.2 | GO:0046688 | response to copper ion(GO:0046688) |
| 0.0 | 0.1 | GO:0006041 | glucosamine metabolic process(GO:0006041) |
| 0.0 | 1.3 | GO:0080171 | lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171) |
| 0.0 | 0.2 | GO:0070574 | cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574) |
| 0.0 | 0.3 | GO:0016486 | peptide hormone processing(GO:0016486) |
| 0.0 | 0.0 | GO:0061055 | myotome development(GO:0061055) |
| 0.0 | 0.5 | GO:0003382 | epithelial cell morphogenesis(GO:0003382) |
| 0.0 | 0.1 | GO:0045925 | positive regulation of female receptivity(GO:0045925) |
| 0.0 | 0.2 | GO:0043653 | mitochondrial fragmentation involved in apoptotic process(GO:0043653) |
| 0.0 | 0.6 | GO:0042982 | amyloid precursor protein metabolic process(GO:0042982) |
| 0.0 | 0.2 | GO:0050901 | leukocyte tethering or rolling(GO:0050901) |
| 0.0 | 0.5 | GO:0007160 | cell-matrix adhesion(GO:0007160) |
| 0.0 | 0.4 | GO:0061157 | mRNA destabilization(GO:0061157) |
| 0.0 | 0.2 | GO:0045742 | positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186) |
| 0.0 | 0.5 | GO:0048008 | platelet-derived growth factor receptor signaling pathway(GO:0048008) |
| 0.0 | 0.2 | GO:0006198 | cAMP catabolic process(GO:0006198) |
| 0.0 | 0.3 | GO:0006406 | mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427) |
| 0.0 | 0.2 | GO:0042130 | negative regulation of T cell proliferation(GO:0042130) |
| 0.0 | 1.5 | GO:0048813 | dendrite morphogenesis(GO:0048813) |
| 0.0 | 1.5 | GO:0046488 | phosphatidylinositol metabolic process(GO:0046488) |
| 0.0 | 0.3 | GO:0043171 | peptide catabolic process(GO:0043171) |
| 0.0 | 0.2 | GO:0031954 | positive regulation of protein autophosphorylation(GO:0031954) |
| 0.0 | 0.0 | GO:1902219 | regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902218) negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219) |
| 0.0 | 0.5 | GO:0072384 | organelle transport along microtubule(GO:0072384) |
| 0.0 | 0.4 | GO:0006730 | one-carbon metabolic process(GO:0006730) |
| 0.0 | 0.2 | GO:0043567 | regulation of insulin-like growth factor receptor signaling pathway(GO:0043567) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 4.1 | GO:0033596 | TSC1-TSC2 complex(GO:0033596) |
| 1.0 | 4.0 | GO:0044307 | dendritic branch(GO:0044307) |
| 1.0 | 4.8 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
| 0.9 | 3.8 | GO:0031673 | H zone(GO:0031673) |
| 0.8 | 3.2 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) |
| 0.8 | 3.0 | GO:1902737 | viral replication complex(GO:0019034) dendritic filopodium(GO:1902737) |
| 0.7 | 2.1 | GO:0098855 | HCN channel complex(GO:0098855) |
| 0.6 | 5.0 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.5 | 14.5 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.4 | 5.1 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.4 | 1.2 | GO:0043512 | inhibin A complex(GO:0043512) |
| 0.3 | 4.1 | GO:0030057 | desmosome(GO:0030057) |
| 0.3 | 1.5 | GO:0030314 | junctional membrane complex(GO:0030314) |
| 0.3 | 0.9 | GO:0005899 | insulin receptor complex(GO:0005899) |
| 0.3 | 0.8 | GO:0098835 | presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) |
| 0.3 | 0.8 | GO:0016939 | kinesin II complex(GO:0016939) |
| 0.3 | 3.9 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.2 | 1.4 | GO:0035976 | AP1 complex(GO:0035976) |
| 0.2 | 4.5 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
| 0.2 | 1.1 | GO:1990130 | Iml1 complex(GO:1990130) |
| 0.2 | 1.7 | GO:0033391 | chromatoid body(GO:0033391) |
| 0.2 | 0.8 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 0.2 | 3.8 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.2 | 2.5 | GO:1990635 | proximal dendrite(GO:1990635) |
| 0.2 | 2.1 | GO:0000812 | Swr1 complex(GO:0000812) |
| 0.2 | 6.9 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.2 | 1.0 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
| 0.2 | 0.5 | GO:0014802 | terminal cisterna(GO:0014802) |
| 0.2 | 1.3 | GO:0097433 | dense body(GO:0097433) |
| 0.2 | 0.5 | GO:0005943 | phosphatidylinositol 3-kinase complex, class IA(GO:0005943) |
| 0.2 | 1.4 | GO:0032300 | mismatch repair complex(GO:0032300) |
| 0.1 | 1.4 | GO:0071141 | SMAD protein complex(GO:0071141) |
| 0.1 | 1.5 | GO:0032426 | stereocilium tip(GO:0032426) |
| 0.1 | 3.0 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 0.1 | 0.4 | GO:0044753 | amphisome(GO:0044753) |
| 0.1 | 2.1 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
| 0.1 | 4.4 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
| 0.1 | 0.4 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
| 0.1 | 1.8 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.1 | 10.2 | GO:0016605 | PML body(GO:0016605) |
| 0.1 | 4.9 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.1 | 1.7 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.1 | 1.4 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.1 | 1.1 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
| 0.1 | 0.8 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 0.1 | 2.4 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.1 | 1.9 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.1 | 0.8 | GO:0044327 | dendritic spine head(GO:0044327) |
| 0.1 | 0.7 | GO:0097227 | sperm annulus(GO:0097227) |
| 0.1 | 0.5 | GO:0061689 | tricellular tight junction(GO:0061689) |
| 0.1 | 0.6 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.1 | 0.4 | GO:0036454 | insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) |
| 0.1 | 0.2 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.1 | 1.1 | GO:0032433 | filopodium tip(GO:0032433) |
| 0.1 | 1.0 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.1 | 3.7 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.1 | 1.0 | GO:0031083 | BLOC-1 complex(GO:0031083) |
| 0.1 | 4.2 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.1 | 3.1 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.1 | 0.7 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.1 | 1.4 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.1 | 0.9 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.1 | 0.9 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 0.1 | 0.5 | GO:0071598 | neuronal ribonucleoprotein granule(GO:0071598) |
| 0.1 | 1.1 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.1 | 0.4 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
| 0.1 | 0.3 | GO:0044615 | nuclear pore nuclear basket(GO:0044615) |
| 0.1 | 2.4 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.1 | 0.2 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.0 | 1.5 | GO:0097546 | ciliary base(GO:0097546) |
| 0.0 | 0.3 | GO:0090571 | RNA polymerase II transcription repressor complex(GO:0090571) |
| 0.0 | 1.0 | GO:0030673 | axolemma(GO:0030673) |
| 0.0 | 0.3 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.0 | 0.6 | GO:0045180 | basal cortex(GO:0045180) |
| 0.0 | 0.4 | GO:0071439 | clathrin complex(GO:0071439) |
| 0.0 | 0.2 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.0 | 0.5 | GO:0044232 | organelle membrane contact site(GO:0044232) |
| 0.0 | 1.0 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 0.0 | 1.2 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.0 | 1.8 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.0 | 1.3 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.0 | 2.0 | GO:0030667 | secretory granule membrane(GO:0030667) |
| 0.0 | 1.5 | GO:0045335 | phagocytic vesicle(GO:0045335) |
| 0.0 | 11.8 | GO:0014069 | postsynaptic density(GO:0014069) |
| 0.0 | 6.9 | GO:0098852 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
| 0.0 | 2.1 | GO:0030139 | endocytic vesicle(GO:0030139) |
| 0.0 | 0.4 | GO:0005922 | connexon complex(GO:0005922) |
| 0.0 | 0.1 | GO:0032279 | asymmetric synapse(GO:0032279) |
| 0.0 | 0.4 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.0 | 0.1 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
| 0.0 | 1.0 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.0 | 0.1 | GO:0012510 | trans-Golgi network transport vesicle membrane(GO:0012510) |
| 0.0 | 1.7 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.0 | 6.2 | GO:0005764 | lytic vacuole(GO:0000323) lysosome(GO:0005764) |
| 0.0 | 17.1 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
| 0.0 | 3.3 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.0 | 1.3 | GO:0035097 | histone methyltransferase complex(GO:0035097) |
| 0.0 | 0.1 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
| 0.0 | 3.1 | GO:0000139 | Golgi membrane(GO:0000139) |
| 0.0 | 0.2 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.0 | 1.8 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.0 | 0.3 | GO:0032420 | stereocilium(GO:0032420) |
| 0.0 | 0.6 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
| 0.0 | 0.3 | GO:0031526 | brush border membrane(GO:0031526) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.7 | 8.0 | GO:0036313 | phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313) |
| 2.6 | 18.0 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 1.1 | 4.3 | GO:0015349 | thyroid hormone transmembrane transporter activity(GO:0015349) |
| 1.0 | 4.1 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.9 | 3.6 | GO:0051032 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 0.8 | 2.5 | GO:0030549 | acetylcholine receptor activator activity(GO:0030549) |
| 0.6 | 5.0 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
| 0.6 | 6.4 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.6 | 1.7 | GO:0030226 | apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556) |
| 0.5 | 3.8 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.5 | 1.6 | GO:0003796 | lysozyme activity(GO:0003796) |
| 0.5 | 13.1 | GO:0042287 | MHC protein binding(GO:0042287) |
| 0.5 | 2.1 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
| 0.5 | 1.6 | GO:0016494 | C-X-C chemokine receptor activity(GO:0016494) |
| 0.5 | 1.4 | GO:0035500 | MH2 domain binding(GO:0035500) |
| 0.5 | 1.9 | GO:0016909 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
| 0.4 | 1.8 | GO:0000179 | rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) |
| 0.4 | 2.2 | GO:0003835 | beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835) |
| 0.4 | 3.0 | GO:0033592 | RNA strand annealing activity(GO:0033592) |
| 0.4 | 3.7 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
| 0.4 | 1.6 | GO:0005008 | hepatocyte growth factor-activated receptor activity(GO:0005008) |
| 0.4 | 1.9 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
| 0.4 | 3.7 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.4 | 1.4 | GO:0019237 | centromeric DNA binding(GO:0019237) |
| 0.3 | 1.0 | GO:0035651 | AP-3 adaptor complex binding(GO:0035651) |
| 0.3 | 0.9 | GO:0000386 | second spliceosomal transesterification activity(GO:0000386) |
| 0.3 | 2.4 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
| 0.3 | 1.2 | GO:0047275 | glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275) |
| 0.3 | 0.9 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
| 0.3 | 1.9 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.3 | 1.1 | GO:0004699 | calcium-independent protein kinase C activity(GO:0004699) |
| 0.3 | 1.9 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
| 0.3 | 3.2 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.3 | 5.5 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.3 | 2.3 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.3 | 0.8 | GO:0002153 | steroid receptor RNA activator RNA binding(GO:0002153) |
| 0.2 | 2.1 | GO:0004033 | aldo-keto reductase (NADP) activity(GO:0004033) |
| 0.2 | 0.7 | GO:0008502 | melatonin receptor activity(GO:0008502) |
| 0.2 | 3.9 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.2 | 3.9 | GO:0030247 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
| 0.2 | 1.3 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
| 0.2 | 1.2 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
| 0.2 | 1.0 | GO:0042610 | CD8 receptor binding(GO:0042610) |
| 0.2 | 2.4 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.2 | 1.2 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.2 | 1.6 | GO:0015181 | arginine transmembrane transporter activity(GO:0015181) |
| 0.2 | 3.9 | GO:0031402 | sodium ion binding(GO:0031402) |
| 0.2 | 1.7 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 0.2 | 1.3 | GO:0015091 | ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510) |
| 0.2 | 0.6 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
| 0.2 | 4.1 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
| 0.2 | 0.5 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
| 0.2 | 2.3 | GO:0004300 | enoyl-CoA hydratase activity(GO:0004300) |
| 0.2 | 1.1 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
| 0.2 | 0.5 | GO:0060072 | large conductance calcium-activated potassium channel activity(GO:0060072) |
| 0.2 | 1.8 | GO:0017162 | aryl hydrocarbon receptor binding(GO:0017162) |
| 0.2 | 0.9 | GO:0004849 | uridine kinase activity(GO:0004849) |
| 0.2 | 2.3 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.2 | 0.6 | GO:0042328 | heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328) |
| 0.2 | 0.8 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.2 | 1.4 | GO:0071253 | connexin binding(GO:0071253) |
| 0.2 | 4.2 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.1 | 4.7 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.1 | 0.8 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 0.1 | 1.2 | GO:0005243 | gap junction channel activity(GO:0005243) |
| 0.1 | 0.4 | GO:0005118 | sevenless binding(GO:0005118) |
| 0.1 | 1.0 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
| 0.1 | 1.4 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
| 0.1 | 1.0 | GO:0008417 | fucosyltransferase activity(GO:0008417) |
| 0.1 | 0.7 | GO:0097001 | ceramide binding(GO:0097001) |
| 0.1 | 1.1 | GO:0030346 | protein phosphatase 2B binding(GO:0030346) |
| 0.1 | 1.2 | GO:0090482 | vitamin transmembrane transporter activity(GO:0090482) |
| 0.1 | 0.7 | GO:0008294 | calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294) |
| 0.1 | 2.8 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.1 | 0.4 | GO:0050816 | phosphothreonine binding(GO:0050816) |
| 0.1 | 1.1 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.1 | 0.6 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
| 0.1 | 5.2 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.1 | 0.3 | GO:0033192 | calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192) |
| 0.1 | 2.0 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.1 | 0.2 | GO:0098809 | nitrite reductase activity(GO:0098809) |
| 0.1 | 0.2 | GO:0001875 | lipopolysaccharide receptor activity(GO:0001875) |
| 0.1 | 0.4 | GO:0004724 | magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724) |
| 0.1 | 0.5 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
| 0.1 | 0.9 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.1 | 0.6 | GO:0050693 | LBD domain binding(GO:0050693) |
| 0.1 | 3.7 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 0.1 | 0.7 | GO:0015114 | phosphate ion transmembrane transporter activity(GO:0015114) |
| 0.1 | 0.2 | GO:0015232 | heme transporter activity(GO:0015232) |
| 0.1 | 0.8 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.1 | 2.1 | GO:0001223 | transcription coactivator binding(GO:0001223) |
| 0.1 | 0.5 | GO:0008376 | acetylgalactosaminyltransferase activity(GO:0008376) |
| 0.1 | 0.5 | GO:0046934 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813) |
| 0.1 | 0.6 | GO:0005338 | nucleotide-sugar transmembrane transporter activity(GO:0005338) |
| 0.1 | 2.0 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.1 | 0.4 | GO:0048101 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
| 0.1 | 0.6 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.1 | 4.1 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
| 0.1 | 6.9 | GO:0001191 | transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191) |
| 0.1 | 0.2 | GO:0042134 | rRNA primary transcript binding(GO:0042134) |
| 0.1 | 0.2 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
| 0.1 | 1.4 | GO:0031690 | adrenergic receptor binding(GO:0031690) |
| 0.1 | 0.9 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.1 | 0.4 | GO:0031994 | insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995) |
| 0.1 | 0.5 | GO:0001846 | opsonin binding(GO:0001846) |
| 0.1 | 0.9 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
| 0.0 | 0.5 | GO:0015093 | iron ion transmembrane transporter activity(GO:0005381) ferrous iron transmembrane transporter activity(GO:0015093) |
| 0.0 | 0.7 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.0 | 0.4 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.0 | 0.8 | GO:0042056 | chemoattractant activity(GO:0042056) |
| 0.0 | 0.2 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
| 0.0 | 3.2 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 2.4 | GO:0003823 | antigen binding(GO:0003823) |
| 0.0 | 0.9 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.0 | 1.0 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.0 | 0.2 | GO:0004322 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.0 | 0.8 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.0 | 0.2 | GO:0071532 | ankyrin repeat binding(GO:0071532) |
| 0.0 | 0.4 | GO:0019531 | secondary active sulfate transmembrane transporter activity(GO:0008271) sulfate transmembrane transporter activity(GO:0015116) oxalate transmembrane transporter activity(GO:0019531) |
| 0.0 | 0.4 | GO:0009922 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.0 | 1.3 | GO:0008028 | monocarboxylic acid transmembrane transporter activity(GO:0008028) |
| 0.0 | 0.1 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
| 0.0 | 0.4 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
| 0.0 | 0.4 | GO:0000900 | translation repressor activity, nucleic acid binding(GO:0000900) |
| 0.0 | 0.1 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
| 0.0 | 0.3 | GO:0016428 | tRNA (cytosine-5-)-methyltransferase activity(GO:0016428) |
| 0.0 | 0.4 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.0 | 0.2 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.0 | 0.5 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.0 | 0.4 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.0 | 0.1 | GO:0004382 | guanosine-diphosphatase activity(GO:0004382) |
| 0.0 | 0.1 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
| 0.0 | 0.3 | GO:0005521 | lamin binding(GO:0005521) |
| 0.0 | 0.9 | GO:0043531 | ADP binding(GO:0043531) |
| 0.0 | 0.8 | GO:0050681 | androgen receptor binding(GO:0050681) |
| 0.0 | 0.2 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.0 | 2.9 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
| 0.0 | 0.1 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
| 0.0 | 1.8 | GO:0002039 | p53 binding(GO:0002039) |
| 0.0 | 0.0 | GO:0043426 | MRF binding(GO:0043426) |
| 0.0 | 0.7 | GO:0070840 | dynein complex binding(GO:0070840) |
| 0.0 | 0.4 | GO:0005112 | Notch binding(GO:0005112) |
| 0.0 | 1.2 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.0 | 3.1 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.0 | 0.1 | GO:0044548 | S100 protein binding(GO:0044548) |
| 0.0 | 0.1 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
| 0.0 | 0.8 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
| 0.0 | 1.1 | GO:0019003 | GDP binding(GO:0019003) |
| 0.0 | 0.2 | GO:0004622 | lysophospholipase activity(GO:0004622) |
| 0.0 | 0.4 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.0 | 9.9 | GO:0005509 | calcium ion binding(GO:0005509) |
| 0.0 | 2.0 | GO:0051117 | ATPase binding(GO:0051117) |
| 0.0 | 0.2 | GO:0047555 | 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555) |
| 0.0 | 0.4 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
| 0.0 | 0.4 | GO:0001671 | ATPase activator activity(GO:0001671) |
| 0.0 | 1.5 | GO:0051219 | phosphoprotein binding(GO:0051219) |
| 0.0 | 1.1 | GO:0008081 | phosphoric diester hydrolase activity(GO:0008081) |
| 0.0 | 0.7 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
| 0.0 | 0.8 | GO:0032934 | cholesterol binding(GO:0015485) sterol binding(GO:0032934) |
| 0.0 | 1.7 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.0 | 0.8 | GO:0016620 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620) |
| 0.0 | 0.6 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.0 | 0.3 | GO:0031593 | polyubiquitin binding(GO:0031593) |
| 0.0 | 1.0 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 0.1 | GO:0016308 | 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308) |
| 0.0 | 0.2 | GO:0031369 | translation initiation factor binding(GO:0031369) |
| 0.0 | 0.1 | GO:0003910 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
| 0.0 | 0.1 | GO:0008519 | ammonium transmembrane transporter activity(GO:0008519) leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842) |
| 0.0 | 0.0 | GO:0003963 | RNA-3'-phosphate cyclase activity(GO:0003963) |
| 0.0 | 0.2 | GO:0042165 | neurotransmitter binding(GO:0042165) |
| 0.0 | 0.4 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.0 | 0.2 | GO:0000983 | transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983) |
| 0.0 | 0.6 | GO:0008276 | protein methyltransferase activity(GO:0008276) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 20.6 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.2 | 4.1 | PID_CIRCADIAN_PATHWAY | Circadian rhythm pathway |
| 0.2 | 9.8 | PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.2 | 10.4 | PID_FOXO_PATHWAY | FoxO family signaling |
| 0.2 | 3.2 | PID_INTEGRIN5_PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.2 | 5.6 | PID_IL3_PATHWAY | IL3-mediated signaling events |
| 0.1 | 9.2 | PID_LKB1_PATHWAY | LKB1 signaling events |
| 0.1 | 1.7 | PID_EPHA2_FWD_PATHWAY | EPHA2 forward signaling |
| 0.1 | 3.5 | PID_ECADHERIN_KERATINOCYTE_PATHWAY | E-cadherin signaling in keratinocytes |
| 0.1 | 4.0 | PID_IL6_7_PATHWAY | IL6-mediated signaling events |
| 0.1 | 2.6 | PID_EPHRINB_REV_PATHWAY | Ephrin B reverse signaling |
| 0.1 | 2.5 | ST_G_ALPHA_I_PATHWAY | G alpha i Pathway |
| 0.1 | 2.6 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.1 | 1.8 | PID_ARF6_DOWNSTREAM_PATHWAY | Arf6 downstream pathway |
| 0.1 | 0.7 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.1 | 2.5 | PID_TCPTP_PATHWAY | Signaling events mediated by TCPTP |
| 0.1 | 0.9 | ST_JNK_MAPK_PATHWAY | JNK MAPK Pathway |
| 0.1 | 1.7 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
| 0.1 | 2.0 | PID_ILK_PATHWAY | Integrin-linked kinase signaling |
| 0.0 | 1.8 | PID_ERBB1_INTERNALIZATION_PATHWAY | Internalization of ErbB1 |
| 0.0 | 0.2 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
| 0.0 | 1.0 | PID_WNT_CANONICAL_PATHWAY | Canonical Wnt signaling pathway |
| 0.0 | 0.2 | ST_WNT_CA2_CYCLIC_GMP_PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.0 | 2.2 | PID_P53_REGULATION_PATHWAY | p53 pathway |
| 0.0 | 1.9 | PID_TXA2PATHWAY | Thromboxane A2 receptor signaling |
| 0.0 | 0.6 | PID_MYC_PATHWAY | C-MYC pathway |
| 0.0 | 1.0 | PID_IFNG_PATHWAY | IFN-gamma pathway |
| 0.0 | 1.4 | PID_RXR_VDR_PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.0 | 0.8 | SA_CASPASE_CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.0 | 4.7 | NABA_ECM_GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 0.8 | PID_SHP2_PATHWAY | SHP2 signaling |
| 0.0 | 0.9 | PID_PS1_PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.0 | 5.6 | NABA_SECRETED_FACTORS | Genes encoding secreted soluble factors |
| 0.0 | 1.5 | PID_CDC42_PATHWAY | CDC42 signaling events |
| 0.0 | 1.3 | PID_AR_TF_PATHWAY | Regulation of Androgen receptor activity |
| 0.0 | 0.7 | PID_ENDOTHELIN_PATHWAY | Endothelins |
| 0.0 | 2.2 | PID_P53_DOWNSTREAM_PATHWAY | Direct p53 effectors |
| 0.0 | 1.3 | PID_ERA_GENOMIC_PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 1.4 | PID_BETA_CATENIN_NUC_PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.0 | 0.4 | PID_RHOA_PATHWAY | RhoA signaling pathway |
| 0.0 | 0.4 | PID_INTEGRIN_A4B1_PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.0 | 0.7 | PID_TGFBR_PATHWAY | TGF-beta receptor signaling |
| 0.0 | 0.4 | PID_IL1_PATHWAY | IL1-mediated signaling events |
| 0.0 | 0.2 | PID_IL12_STAT4_PATHWAY | IL12 signaling mediated by STAT4 |
| 0.0 | 0.1 | PID_EPHA_FWDPATHWAY | EPHA forward signaling |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 4.3 | REACTOME_TRANSPORT_OF_ORGANIC_ANIONS | Genes involved in Transport of organic anions |
| 0.4 | 7.9 | REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.3 | 4.2 | REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.3 | 3.2 | REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
| 0.3 | 1.2 | REACTOME_GLYCOPROTEIN_HORMONES | Genes involved in Glycoprotein hormones |
| 0.3 | 5.8 | REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB | Genes involved in PKA-mediated phosphorylation of CREB |
| 0.2 | 4.7 | REACTOME_CRMPS_IN_SEMA3A_SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.2 | 1.5 | REACTOME_THE_NLRP3_INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 0.2 | 0.8 | REACTOME_G_ALPHA1213_SIGNALLING_EVENTS | Genes involved in G alpha (12/13) signalling events |
| 0.2 | 4.0 | REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII | Genes involved in CREB phosphorylation through the activation of CaMKII |
| 0.1 | 5.2 | REACTOME_LYSOSOME_VESICLE_BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 0.1 | 3.4 | REACTOME_ERK_MAPK_TARGETS | Genes involved in ERK/MAPK targets |
| 0.1 | 1.4 | REACTOME_DSCAM_INTERACTIONS | Genes involved in DSCAM interactions |
| 0.1 | 4.0 | REACTOME_MYOGENESIS | Genes involved in Myogenesis |
| 0.1 | 1.7 | REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING | Genes involved in Spry regulation of FGF signaling |
| 0.1 | 2.8 | REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.1 | 4.5 | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.1 | 1.9 | REACTOME_SIGNALING_BY_NOTCH4 | Genes involved in Signaling by NOTCH4 |
| 0.1 | 1.4 | REACTOME_MEIOTIC_RECOMBINATION | Genes involved in Meiotic Recombination |
| 0.1 | 1.0 | REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.1 | 1.8 | REACTOME_TIE2_SIGNALING | Genes involved in Tie2 Signaling |
| 0.1 | 0.5 | REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
| 0.1 | 0.4 | REACTOME_NRIF_SIGNALS_CELL_DEATH_FROM_THE_NUCLEUS | Genes involved in NRIF signals cell death from the nucleus |
| 0.1 | 0.9 | REACTOME_SHC_RELATED_EVENTS | Genes involved in SHC-related events |
| 0.1 | 2.1 | REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.1 | 1.4 | REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.1 | 0.9 | REACTOME_HDL_MEDIATED_LIPID_TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.1 | 1.9 | REACTOME_EGFR_DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.1 | 1.1 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
| 0.1 | 1.4 | REACTOME_EARLY_PHASE_OF_HIV_LIFE_CYCLE | Genes involved in Early Phase of HIV Life Cycle |
| 0.1 | 0.8 | REACTOME_GAP_JUNCTION_DEGRADATION | Genes involved in Gap junction degradation |
| 0.1 | 1.7 | REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE | Genes involved in GPVI-mediated activation cascade |
| 0.1 | 0.7 | REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.1 | 0.7 | REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION | Genes involved in FGFR1 ligand binding and activation |
| 0.1 | 0.9 | REACTOME_GABA_A_RECEPTOR_ACTIVATION | Genes involved in GABA A receptor activation |
| 0.1 | 2.1 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.1 | 4.3 | REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.1 | 1.5 | REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.1 | 0.4 | REACTOME_CA_DEPENDENT_EVENTS | Genes involved in Ca-dependent events |
| 0.1 | 0.3 | REACTOME_IL_7_SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.0 | 1.6 | REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING | Genes involved in Sema4D in semaphorin signaling |
| 0.0 | 3.5 | REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.0 | 5.0 | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.0 | 0.6 | REACTOME_ACTIVATION_OF_CHAPERONES_BY_ATF6_ALPHA | Genes involved in Activation of Chaperones by ATF6-alpha |
| 0.0 | 0.5 | REACTOME_GAP_JUNCTION_ASSEMBLY | Genes involved in Gap junction assembly |
| 0.0 | 1.1 | REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.0 | 1.1 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI | Genes involved in N-glycan antennae elongation in the medial/trans-Golgi |
| 0.0 | 2.7 | REACTOME_POTASSIUM_CHANNELS | Genes involved in Potassium Channels |
| 0.0 | 0.8 | REACTOME_DARPP_32_EVENTS | Genes involved in DARPP-32 events |
| 0.0 | 0.3 | REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
| 0.0 | 1.2 | REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.0 | 1.1 | REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS | Genes involved in G alpha (z) signalling events |
| 0.0 | 0.1 | REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION_ | Genes involved in Cyclin E associated events during G1/S transition |
| 0.0 | 0.6 | REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.0 | 1.0 | REACTOME_TIGHT_JUNCTION_INTERACTIONS | Genes involved in Tight junction interactions |
| 0.0 | 0.2 | REACTOME_TRAF6_MEDIATED_INDUCTION_OF_TAK1_COMPLEX | Genes involved in TRAF6 mediated induction of TAK1 complex |
| 0.0 | 1.1 | REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.0 | 1.0 | REACTOME_GLUCOSE_TRANSPORT | Genes involved in Glucose transport |
| 0.0 | 0.6 | REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.0 | 0.2 | REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.0 | 0.6 | REACTOME_REGULATORY_RNA_PATHWAYS | Genes involved in Regulatory RNA pathways |
| 0.0 | 0.4 | REACTOME_INSULIN_RECEPTOR_RECYCLING | Genes involved in Insulin receptor recycling |
| 0.0 | 0.1 | REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
| 0.0 | 0.4 | REACTOME_METAL_ION_SLC_TRANSPORTERS | Genes involved in Metal ion SLC transporters |
| 0.0 | 0.4 | REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.0 | 0.2 | REACTOME_HYALURONAN_METABOLISM | Genes involved in Hyaluronan metabolism |
| 0.0 | 1.1 | REACTOME_DNA_REPAIR | Genes involved in DNA Repair |
| 0.0 | 0.3 | REACTOME_CELL_CELL_JUNCTION_ORGANIZATION | Genes involved in Cell-cell junction organization |
| 0.0 | 0.1 | REACTOME_AMINE_LIGAND_BINDING_RECEPTORS | Genes involved in Amine ligand-binding receptors |
| 0.0 | 0.4 | REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
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