Motif ID: Foxq1

Z-value: 1.034


Transcription factors associated with Foxq1:

Gene SymbolEntrez IDGene Name
Foxq1 ENSMUSG00000038415.8 Foxq1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxq1mm10_v2_chr13_+_31558157_315581760.256.3e-02Click!


Activity profile for motif Foxq1.

activity profile for motif Foxq1


Sorted Z-values histogram for motif Foxq1

Sorted Z-values for motif Foxq1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxq1

PNG image of the network

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Top targets:


Showing 1 to 20 of 131 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_-_30353468 11.615 ENSMUST00000112249.1
 Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chrX_-_103483205 10.802 ENSMUST00000127786.2
 Xist
inactive X specific transcripts
chr2_-_77519565 9.095 ENSMUST00000111830.2
 Zfp385b
zinc finger protein 385B
chr2_+_76406529 7.881 ENSMUST00000111929.1
ENSMUST00000077972.4
ENSMUST00000111930.2
 Osbpl6


oxysterol binding protein-like 6


chr16_+_43363855 7.641 ENSMUST00000156367.1
 Zbtb20
zinc finger and BTB domain containing 20
chr10_+_60106452 7.269 ENSMUST00000165024.2
 Spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr18_-_89769479 6.684 ENSMUST00000097495.3
 Dok6
docking protein 6
chr18_+_37496997 6.331 ENSMUST00000059571.5
 Pcdhb19
protocadherin beta 19
chr18_+_51117754 6.089 ENSMUST00000116639.2
 Prr16
proline rich 16
chr18_+_37442517 6.065 ENSMUST00000056915.1
 Pcdhb13
protocadherin beta 13
chr16_+_43364145 5.973 ENSMUST00000148775.1
 Zbtb20
zinc finger and BTB domain containing 20
chr5_-_122002340 5.718 ENSMUST00000134326.1
 Cux2
cut-like homeobox 2
chr17_+_35076902 4.950 ENSMUST00000172494.1
ENSMUST00000172678.1
ENSMUST00000013910.4
 Ly6g6e


lymphocyte antigen 6 complex, locus G6E


chr4_-_129121889 4.938 ENSMUST00000139450.1
ENSMUST00000125931.1
ENSMUST00000116444.2
 Hpca


hippocalcin


chr18_+_37489465 4.890 ENSMUST00000055949.2
 Pcdhb18
protocadherin beta 18
chr5_+_122643878 4.766 ENSMUST00000100737.3
ENSMUST00000121489.1
ENSMUST00000031425.8
ENSMUST00000086247.5
 P2rx7



purinergic receptor P2X, ligand-gated ion channel, 7



chr8_-_84773381 4.672 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr1_+_51289106 4.657 ENSMUST00000051572.6
 Sdpr
serum deprivation response
chr18_+_37518341 4.623 ENSMUST00000097609.1
 Pcdhb22
protocadherin beta 22
chr15_-_58214882 4.397 ENSMUST00000022986.6
 Fbxo32
F-box protein 32

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 66 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 28.1 GO:0007416 synapse assembly(GO:0007416)
0.3 13.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
2.9 11.6 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
3.6 10.8 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 9.8 GO:0006869 lipid transport(GO:0006869)
0.1 9.5 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.9 8.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.5 8.0 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.3 8.0 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
0.3 7.1 GO:0007614 short-term memory(GO:0007614)
0.3 6.1 GO:0045793 positive regulation of cell size(GO:0045793)
1.6 4.9 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
1.6 4.8 GO:0032650 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) interleukin-1 alpha secretion(GO:0050703) regulation of bleb assembly(GO:1904170)
0.3 4.7 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
2.2 4.4 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.6 4.2 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.1 3.9 GO:0034605 cellular response to heat(GO:0034605)
0.1 3.8 GO:0006376 mRNA splice site selection(GO:0006376)
0.3 3.7 GO:0042118 endothelial cell activation(GO:0042118)
0.3 3.7 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 27.8 GO:0005887 integral component of plasma membrane(GO:0005887)
1.2 11.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
1.1 10.8 GO:0000805 X chromosome(GO:0000805)
0.2 9.0 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 8.5 GO:0001650 fibrillar center(GO:0001650)
0.3 8.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.2 8.0 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 5.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.4 4.9 GO:0044327 dendritic spine head(GO:0044327)
0.3 4.8 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 4.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 4.2 GO:0072686 mitotic spindle(GO:0072686)
0.0 3.7 GO:0032993 protein-DNA complex(GO:0032993)
0.0 3.4 GO:0000139 Golgi membrane(GO:0000139)
0.2 2.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 2.5 GO:0055037 recycling endosome(GO:0055037)
0.2 2.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 2.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.5 2.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.1 2.0 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 50 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 20.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
1.5 11.6 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0 11.5 GO:0005509 calcium ion binding(GO:0005509)
0.1 10.2 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.1 8.4 GO:0050840 extracellular matrix binding(GO:0050840)
2.7 8.0 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.0 6.3 GO:0008017 microtubule binding(GO:0008017)
0.1 5.6 GO:0002039 p53 binding(GO:0002039)
0.8 4.8 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 3.8 GO:0036002 pre-mRNA binding(GO:0036002)
0.9 3.7 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 3.7 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.4 3.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 3.3 GO:0005158 insulin receptor binding(GO:0005158)
0.0 3.1 GO:0005516 calmodulin binding(GO:0005516)
0.3 2.9 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.3 2.9 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.2 2.6 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 2.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.8 2.3 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)

Gene overrepresentation in C2:CP category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 8.4 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.1 4.4 PID_FOXO_PATHWAY FoxO family signaling
0.1 3.6 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 3.2 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.1 2.9 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.0 2.2 NABA_COLLAGENS Genes encoding collagen proteins
0.1 1.3 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 1.3 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 1.1 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 0.8 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.8 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 4.8 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.3 3.8 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.1 3.7 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 2.9 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 2.2 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 2.2 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 2.0 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.1 2.0 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 2.0 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.5 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.1 1.3 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 1.2 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 1.2 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.1 REACTOME_PLC_BETA_MEDIATED_EVENTS Genes involved in PLC beta mediated events
0.1 0.8 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.8 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.6 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.5 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.3 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.3 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation