Motif ID: Fubp1
Z-value: 0.692
Transcription factors associated with Fubp1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Fubp1 | ENSMUSG00000028034.9 | Fubp1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Fubp1 | mm10_v2_chr3_+_152210458_152210534 | -0.07 | 5.9e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 2.2 | GO:0046552 | eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552) |
| 0.5 | 3.6 | GO:0016185 | synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) |
| 0.5 | 6.1 | GO:0097067 | cellular response to thyroid hormone stimulus(GO:0097067) |
| 0.4 | 1.3 | GO:0015747 | urate transport(GO:0015747) |
| 0.4 | 1.3 | GO:0060244 | negative regulation of cell proliferation involved in contact inhibition(GO:0060244) |
| 0.4 | 4.1 | GO:0006027 | glycosaminoglycan catabolic process(GO:0006027) |
| 0.4 | 1.2 | GO:0014738 | regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900) |
| 0.3 | 1.6 | GO:1903609 | negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609) |
| 0.3 | 0.9 | GO:0050883 | regulation of sulfur amino acid metabolic process(GO:0031335) musculoskeletal movement, spinal reflex action(GO:0050883) |
| 0.3 | 0.9 | GO:1905065 | cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344) positive regulation of vascular smooth muscle cell differentiation(GO:1905065) |
| 0.2 | 1.0 | GO:0050904 | diapedesis(GO:0050904) |
| 0.2 | 0.5 | GO:0021913 | regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) |
| 0.2 | 0.7 | GO:0002430 | complement receptor mediated signaling pathway(GO:0002430) |
| 0.2 | 0.5 | GO:0060672 | epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672) |
| 0.2 | 1.2 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
| 0.2 | 0.5 | GO:0061300 | cerebellum vasculature development(GO:0061300) |
| 0.2 | 0.5 | GO:0002184 | cytoplasmic translational termination(GO:0002184) |
| 0.2 | 1.2 | GO:0098909 | regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909) |
| 0.2 | 0.5 | GO:0046881 | sperm ejaculation(GO:0042713) positive regulation of follicle-stimulating hormone secretion(GO:0046881) |
| 0.2 | 0.5 | GO:0045014 | detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594) |
| 0.1 | 0.6 | GO:1901843 | positive regulation of high voltage-gated calcium channel activity(GO:1901843) |
| 0.1 | 0.6 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
| 0.1 | 0.8 | GO:0005981 | regulation of glycogen catabolic process(GO:0005981) |
| 0.1 | 5.6 | GO:0034605 | cellular response to heat(GO:0034605) |
| 0.1 | 0.5 | GO:0019065 | receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509) |
| 0.1 | 1.4 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
| 0.1 | 1.6 | GO:0010669 | epithelial structure maintenance(GO:0010669) |
| 0.1 | 0.4 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
| 0.1 | 0.2 | GO:1904580 | regulation of intracellular mRNA localization(GO:1904580) |
| 0.1 | 0.3 | GO:0045918 | negative regulation of cytolysis(GO:0045918) |
| 0.1 | 0.3 | GO:0070197 | meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240) |
| 0.1 | 0.4 | GO:0045650 | negative regulation of macrophage differentiation(GO:0045650) |
| 0.1 | 1.5 | GO:0008340 | determination of adult lifespan(GO:0008340) |
| 0.1 | 0.3 | GO:1902951 | negative regulation of dendritic spine maintenance(GO:1902951) |
| 0.0 | 4.5 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
| 0.0 | 2.0 | GO:0006506 | GPI anchor biosynthetic process(GO:0006506) |
| 0.0 | 0.2 | GO:1903378 | positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378) |
| 0.0 | 0.4 | GO:0019243 | methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727) |
| 0.0 | 0.3 | GO:0090043 | regulation of tubulin deacetylation(GO:0090043) |
| 0.0 | 0.3 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.0 | 1.8 | GO:0080171 | lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171) |
| 0.0 | 0.2 | GO:0070475 | rRNA base methylation(GO:0070475) |
| 0.0 | 0.6 | GO:0070266 | necroptotic process(GO:0070266) |
| 0.0 | 0.4 | GO:1902187 | negative regulation of viral release from host cell(GO:1902187) |
| 0.0 | 0.7 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.0 | 0.1 | GO:0048133 | NK T cell differentiation(GO:0001865) germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138) germline stem cell asymmetric division(GO:0098728) |
| 0.0 | 0.2 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
| 0.0 | 0.7 | GO:0032292 | myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292) |
| 0.0 | 1.1 | GO:0030901 | midbrain development(GO:0030901) |
| 0.0 | 0.5 | GO:0043277 | apoptotic cell clearance(GO:0043277) |
| 0.0 | 0.1 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
| 0.0 | 0.5 | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184) |
| 0.0 | 0.5 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
| 0.0 | 0.3 | GO:0033344 | cholesterol efflux(GO:0033344) |
| 0.0 | 0.5 | GO:0015914 | phospholipid transport(GO:0015914) |
| 0.0 | 0.1 | GO:0006362 | transcription elongation from RNA polymerase I promoter(GO:0006362) |
| 0.0 | 0.5 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.0 | 0.4 | GO:0007212 | dopamine receptor signaling pathway(GO:0007212) |
| 0.0 | 0.2 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 1.2 | GO:0043540 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540) |
| 0.2 | 3.6 | GO:0043196 | varicosity(GO:0043196) |
| 0.2 | 1.0 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 0.2 | 0.5 | GO:0018444 | translation release factor complex(GO:0018444) |
| 0.2 | 0.5 | GO:0034673 | inhibin-betaglycan-ActRII complex(GO:0034673) |
| 0.2 | 0.8 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
| 0.1 | 2.0 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 0.1 | 1.6 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.1 | 0.6 | GO:0005859 | muscle myosin complex(GO:0005859) |
| 0.1 | 0.8 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 0.1 | 0.4 | GO:0032585 | multivesicular body membrane(GO:0032585) |
| 0.1 | 0.7 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
| 0.0 | 0.2 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
| 0.0 | 0.4 | GO:0070652 | HAUS complex(GO:0070652) |
| 0.0 | 0.4 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 0.0 | 0.5 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.0 | 0.5 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 0.0 | 1.2 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.0 | 0.2 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
| 0.0 | 0.1 | GO:0031251 | PAN complex(GO:0031251) |
| 0.0 | 0.5 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
| 0.0 | 0.8 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 1.2 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.0 | 0.4 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
| 0.0 | 0.3 | GO:0034362 | low-density lipoprotein particle(GO:0034362) |
| 0.0 | 9.3 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.0 | 0.9 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.0 | 0.3 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
| 0.0 | 1.8 | GO:0030136 | clathrin-coated vesicle(GO:0030136) |
| 0.0 | 0.5 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.0 | 1.6 | GO:0005901 | caveola(GO:0005901) |
| 0.0 | 1.0 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.0 | 0.5 | GO:0016235 | aggresome(GO:0016235) |
| 0.0 | 0.7 | GO:0000786 | nucleosome(GO:0000786) |
| 0.0 | 0.2 | GO:0000421 | autophagosome membrane(GO:0000421) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 3.6 | GO:0031749 | D2 dopamine receptor binding(GO:0031749) |
| 0.3 | 1.3 | GO:0015143 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
| 0.3 | 1.6 | GO:0070320 | inward rectifier potassium channel inhibitor activity(GO:0070320) |
| 0.2 | 3.4 | GO:0070742 | C2H2 zinc finger domain binding(GO:0070742) |
| 0.2 | 1.2 | GO:0001010 | transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) |
| 0.2 | 4.1 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.2 | 1.3 | GO:0001075 | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) |
| 0.2 | 0.7 | GO:0004875 | complement receptor activity(GO:0004875) |
| 0.2 | 2.0 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 0.2 | 1.6 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.2 | 1.2 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
| 0.2 | 1.2 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 0.1 | 6.1 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
| 0.1 | 0.6 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.1 | 0.4 | GO:0016509 | long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509) |
| 0.1 | 0.5 | GO:0017002 | activin-activated receptor activity(GO:0017002) |
| 0.1 | 1.4 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.1 | 0.4 | GO:0051429 | corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
| 0.1 | 1.8 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.1 | 0.3 | GO:0042610 | CD8 receptor binding(GO:0042610) |
| 0.1 | 0.5 | GO:0003747 | translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079) |
| 0.1 | 0.9 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.0 | 0.9 | GO:0015026 | coreceptor activity(GO:0015026) |
| 0.0 | 0.5 | GO:0015037 | peptide disulfide oxidoreductase activity(GO:0015037) |
| 0.0 | 0.8 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.0 | 0.5 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) |
| 0.0 | 0.4 | GO:0050733 | RS domain binding(GO:0050733) |
| 0.0 | 0.2 | GO:0050816 | phosphothreonine binding(GO:0050816) |
| 0.0 | 1.2 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.0 | 0.7 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.0 | 0.6 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.0 | 0.5 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.0 | 5.0 | GO:0005516 | calmodulin binding(GO:0005516) |
| 0.0 | 0.1 | GO:0001165 | RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165) |
| 0.0 | 0.5 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 0.3 | GO:0001848 | complement binding(GO:0001848) |
| 0.0 | 0.4 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.0 | 0.4 | GO:0001222 | transcription corepressor binding(GO:0001222) |
| 0.0 | 0.2 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.0 | 5.5 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
| 0.0 | 0.2 | GO:0030957 | Tat protein binding(GO:0030957) |
| 0.0 | 0.6 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.0 | 0.1 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.0 | 0.6 | GO:0016811 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.6 | PID_IL8_CXCR1_PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.1 | 2.9 | PID_ALK1_PATHWAY | ALK1 signaling events |
| 0.0 | 0.4 | PID_S1P_S1P4_PATHWAY | S1P4 pathway |
| 0.0 | 6.0 | NABA_SECRETED_FACTORS | Genes encoding secreted soluble factors |
| 0.0 | 0.9 | PID_BMP_PATHWAY | BMP receptor signaling |
| 0.0 | 0.5 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
| 0.0 | 1.0 | PID_INTEGRIN3_PATHWAY | Beta3 integrin cell surface interactions |
| 0.0 | 0.3 | PID_SYNDECAN_3_PATHWAY | Syndecan-3-mediated signaling events |
| 0.0 | 0.5 | PID_HNF3B_PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 1.2 | PID_BETA_CATENIN_NUC_PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 3.8 | REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.2 | 1.3 | REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 0.2 | 3.6 | REACTOME_GAP_JUNCTION_DEGRADATION | Genes involved in Gap junction degradation |
| 0.1 | 2.2 | REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.1 | 1.3 | REACTOME_PECAM1_INTERACTIONS | Genes involved in PECAM1 interactions |
| 0.1 | 2.0 | REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.1 | 1.2 | REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
| 0.0 | 4.2 | REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.0 | 0.7 | REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 0.0 | 0.6 | REACTOME_SIGNALING_BY_SCF_KIT | Genes involved in Signaling by SCF-KIT |
| 0.0 | 1.2 | REACTOME_GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.0 | 0.9 | REACTOME_SULFUR_AMINO_ACID_METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.0 | 0.6 | REACTOME_STRIATED_MUSCLE_CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.0 | 0.5 | REACTOME_SIGNALING_BY_NODAL | Genes involved in Signaling by NODAL |
| 0.0 | 1.4 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.0 | 0.5 | REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.0 | 2.1 | REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX | Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex |
| 0.0 | 0.8 | REACTOME_NETRIN1_SIGNALING | Genes involved in Netrin-1 signaling |
| 0.0 | 0.2 | REACTOME_DESTABILIZATION_OF_MRNA_BY_BRF1 | Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1) |
| 0.0 | 0.4 | REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.0 | 0.5 | REACTOME_EGFR_DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.0 | 1.3 | REACTOME_REGULATION_OF_INSULIN_SECRETION | Genes involved in Regulation of Insulin Secretion |
| 0.0 | 0.8 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.0 | 0.5 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.0 | 0.7 | REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES | Genes involved in Cross-presentation of soluble exogenous antigens (endosomes) |
| 0.0 | 0.5 | REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
