---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr13_-_116309639	5.652	ENSMUST00000036060.6	Isl1	ISL1 transcription factor, LIM/homeodomain
chr16_+_45093611	5.206	ENSMUST00000099498.2	Ccdc80	coiled-coil domain containing 80
chr16_+_45094036	5.186	ENSMUST00000061050.5	Ccdc80	coiled-coil domain containing 80
chr11_+_90030295	4.249	ENSMUST00000092788.3	Tmem100	transmembrane protein 100
chr8_+_84701430	3.695	ENSMUST00000037165.4	Lyl1	lymphoblastomic leukemia 1
chr1_-_162866502	3.589	ENSMUST00000046049.7	Fmo1	flavin containing monooxygenase 1
chr2_+_72476159	3.550	ENSMUST00000102691.4	Cdca7	cell division cycle associated 7
chr7_-_4522427	3.459	ENSMUST00000098859.3	Tnni3	troponin I, cardiac 3
chr2_+_72476225	3.257	ENSMUST00000157019.1	Cdca7	cell division cycle associated 7
chr3_+_135825788	2.723	ENSMUST00000167390.1	Slc39a8	solute carrier family 39 (metal ion transporter), member 8
chr4_+_11579647	2.645	ENSMUST00000180239.1	Fsbp	fibrinogen silencer binding protein
chr14_-_54577578	2.616	ENSMUST00000054487.8	Ajuba	ajuba LIM protein
chr3_-_154330543	2.584	ENSMUST00000184966.1 ENSMUST00000177846.2	Lhx8	LIM homeobox protein 8
chr2_-_36104060	2.502	ENSMUST00000112961.3 ENSMUST00000112966.3	Lhx6	LIM homeobox protein 6
chr1_+_172341197	2.480	ENSMUST00000056136.3	Kcnj10	potassium inwardly-rectifying channel, subfamily J, member 10
chr7_-_139582790	2.470	ENSMUST00000106095.2	Nkx6-2	NK6 homeobox 2
chr16_-_95459245	2.251	ENSMUST00000176345.1 ENSMUST00000121809.2 ENSMUST00000118113.1 ENSMUST00000122199.1	Erg	avian erythroblastosis virus E-26 (v-ets) oncogene related
chr6_+_17306335	2.101	ENSMUST00000007799.6 ENSMUST00000115456.1 ENSMUST00000115455.2 ENSMUST00000130505.1	Cav1	caveolin 1, caveolae protein
chr7_-_4522794	2.052	ENSMUST00000140424.1	Tnni3	troponin I, cardiac 3
chr9_-_32541589	2.007	ENSMUST00000016231.7	Fli1	Friend leukemia integration 1
chr3_-_88000350	1.975	ENSMUST00000090971.5	Bcan	brevican
chr19_-_42202150	1.940	ENSMUST00000018966.7	Sfrp5	secreted frizzled-related sequence protein 5
chr2_+_70474923	1.934	ENSMUST00000100043.2	Sp5	trans-acting transcription factor 5
chr7_+_28833975	1.916	ENSMUST00000066723.8	Lgals4	lectin, galactose binding, soluble 4
chr4_-_14621805	1.898	ENSMUST00000042221.7	Slc26a7	solute carrier family 26, member 7
chr7_+_110627650	1.887	ENSMUST00000033054.8	Adm	adrenomedullin
chr6_+_30541582	1.691	ENSMUST00000096066.4	Cpa2	carboxypeptidase A2, pancreatic
chr5_-_125294107	1.677	ENSMUST00000127148.1	Scarb1	scavenger receptor class B, member 1
chrX_-_107403295	1.665	ENSMUST00000033591.5	Itm2a	integral membrane protein 2A
chr18_-_78123324	1.626	ENSMUST00000160292.1 ENSMUST00000091813.5	Slc14a1	solute carrier family 14 (urea transporter), member 1
chr18_+_57142782	1.613	ENSMUST00000139892.1	Megf10	multiple EGF-like-domains 10
chr5_-_121836852	1.426	ENSMUST00000086310.1	Sh2b3	SH2B adaptor protein 3
chr9_-_44342332	1.396	ENSMUST00000097558.3	Hmbs	hydroxymethylbilane synthase
chr11_-_102469839	1.337	ENSMUST00000103086.3	Itga2b	integrin alpha 2b
chr7_-_100662315	1.275	ENSMUST00000151123.1 ENSMUST00000107047.2	Plekhb1	pleckstrin homology domain containing, family B (evectins) member 1
chr15_-_50890396	1.151	ENSMUST00000185183.1	Trps1	trichorhinophalangeal syndrome I (human)
chr6_+_125552948	1.105	ENSMUST00000112254.1 ENSMUST00000112253.1 ENSMUST00000001995.7	Vwf	Von Willebrand factor homolog
chr19_-_7019423	1.103	ENSMUST00000040772.8	Fermt3	fermitin family homolog 3 (Drosophila)
chr3_-_84479418	1.013	ENSMUST00000091002.1	Fhdc1	FH2 domain containing 1
chr5_-_121836810	0.959	ENSMUST00000118580.1 ENSMUST00000040308.7	Sh2b3	SH2B adaptor protein 3
chr19_+_58670358	0.921	ENSMUST00000057270.7	Pnlip	pancreatic lipase
chr10_-_115185015	0.912	ENSMUST00000006949.8	Tph2	tryptophan hydroxylase 2
chrX_+_73757069	0.878	ENSMUST00000002079.6	Plxnb3	plexin B3
chr13_+_38345716	0.869	ENSMUST00000171970.1	Bmp6	bone morphogenetic protein 6
chr10_-_80421847	0.859	ENSMUST00000156244.1	Tcf3	transcription factor 3
chr4_+_41760454	0.859	ENSMUST00000108040.1	Il11ra1	interleukin 11 receptor, alpha chain 1
chr6_+_15185203	0.835	ENSMUST00000154448.1	Foxp2	forkhead box P2
chr4_-_14621669	0.815	ENSMUST00000143105.1	Slc26a7	solute carrier family 26, member 7
chr2_+_26583858	0.812	ENSMUST00000100290.5 ENSMUST00000102907.5	Egfl7	EGF-like domain 7
chr12_-_10900296	0.798	ENSMUST00000085735.2	Pgk1-rs7	phosphoglycerate kinase-1, related sequence-7
chr6_+_17306415	0.793	ENSMUST00000150901.1	Cav1	caveolin 1, caveolae protein
chr13_-_91388079	0.771	ENSMUST00000181054.1	A830009L08Rik	RIKEN cDNA A830009L08 gene
chr3_+_135826075	0.769	ENSMUST00000029810.5	Slc39a8	solute carrier family 39 (metal ion transporter), member 8
chr15_+_76904070	0.768	ENSMUST00000004072.8	Rpl8	ribosomal protein L8
chr7_-_100662414	0.759	ENSMUST00000079176.6	Plekhb1	pleckstrin homology domain containing, family B (evectins) member 1
chr3_-_63851251	0.755	ENSMUST00000162269.2 ENSMUST00000159676.2 ENSMUST00000175947.1	Plch1	phospholipase C, eta 1
chr8_+_84908731	0.715	ENSMUST00000134569.1	Dnase2a	deoxyribonuclease II alpha
chr16_-_44016387	0.688	ENSMUST00000036174.3	Gramd1c	GRAM domain containing 1C
chr16_-_64786321	0.681	ENSMUST00000052588.4	Zfp654	zinc finger protein 654
chr10_-_83648631	0.680	ENSMUST00000146876.2 ENSMUST00000176294.1	Appl2	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr2_+_85037212	0.671	ENSMUST00000077798.6	Ssrp1	structure specific recognition protein 1
chr2_-_77170592	0.653	ENSMUST00000164114.2 ENSMUST00000049544.7	Ccdc141	coiled-coil domain containing 141
chr4_-_14621494	0.637	ENSMUST00000149633.1	Slc26a7	solute carrier family 26, member 7
chr2_-_153241402	0.629	ENSMUST00000056924.7	Plagl2	pleiomorphic adenoma gene-like 2
chr1_-_14310198	0.613	ENSMUST00000168081.2 ENSMUST00000027066.6	Eya1	eyes absent 1 homolog (Drosophila)
chr10_-_13388830	0.586	ENSMUST00000079698.5	Phactr2	phosphatase and actin regulator 2
chr15_-_103251465	0.579	ENSMUST00000133600.1 ENSMUST00000134554.1 ENSMUST00000156927.1 ENSMUST00000149111.1 ENSMUST00000132836.1	Nfe2	nuclear factor, erythroid derived 2
chr4_-_59438633	0.578	ENSMUST00000040166.7 ENSMUST00000107544.1	Susd1	sushi domain containing 1
chrX_+_10485121	0.572	ENSMUST00000076354.6 ENSMUST00000115526.1	Tspan7	tetraspanin 7
chr3_+_79884496	0.562	ENSMUST00000118853.1	Fam198b	family with sequence similarity 198, member B
chr4_-_32923455	0.561	ENSMUST00000035719.4 ENSMUST00000084749.1	Ankrd6	ankyrin repeat domain 6
chr3_+_79884576	0.557	ENSMUST00000145992.1	Fam198b	family with sequence similarity 198, member B
chr14_-_55560340	0.545	ENSMUST00000066106.3	A730061H03Rik	RIKEN cDNA A730061H03 gene
chr3_+_133338936	0.519	ENSMUST00000150386.1 ENSMUST00000125858.1	Ppa2	pyrophosphatase (inorganic) 2
chr17_-_85688252	0.519	ENSMUST00000024947.7 ENSMUST00000163568.2	Six2	sine oculis-related homeobox 2
chr17_-_84682932	0.510	ENSMUST00000066175.3	Abcg5	ATP-binding cassette, sub-family G (WHITE), member 5
chr5_+_24364804	0.498	ENSMUST00000030834.4 ENSMUST00000115090.1	Nos3	nitric oxide synthase 3, endothelial cell
chr8_+_84908560	0.498	ENSMUST00000003910.6 ENSMUST00000109744.1	Dnase2a	deoxyribonuclease II alpha
chr9_-_77251829	0.496	ENSMUST00000184322.1 ENSMUST00000184316.1	Mlip	muscular LMNA-interacting protein
chr17_-_45593626	0.476	ENSMUST00000163905.1 ENSMUST00000167692.1	Slc29a1	solute carrier family 29 (nucleoside transporters), member 1
chr8_+_84908680	0.429	ENSMUST00000145292.1	Dnase2a	deoxyribonuclease II alpha
chr16_+_43503607	0.420	ENSMUST00000126100.1 ENSMUST00000123047.1 ENSMUST00000156981.1	Zbtb20	zinc finger and BTB domain containing 20
chr1_+_75450699	0.417	ENSMUST00000037708.9	Asic4	acid-sensing (proton-gated) ion channel family member 4
chr18_+_7869159	0.374	ENSMUST00000170932.1 ENSMUST00000167020.1	Wac	WW domain containing adaptor with coiled-coil
chr13_-_18031616	0.373	ENSMUST00000099736.2	Vdac3-ps1	voltage-dependent anion channel 3, pseudogene 1
chr1_+_75507077	0.369	ENSMUST00000037330.4	Inha	inhibin alpha
chr1_+_75450436	0.365	ENSMUST00000113577.1	Asic4	acid-sensing (proton-gated) ion channel family member 4
chr14_-_64455903	0.364	ENSMUST00000067927.7	Msra	methionine sulfoxide reductase A
chr7_+_110773658	0.363	ENSMUST00000143786.1	Ampd3	adenosine monophosphate deaminase 3
chr17_+_46650328	0.360	ENSMUST00000043464.7	Cul7	cullin 7
chr6_-_122856151	0.354	ENSMUST00000042081.8	C3ar1	complement component 3a receptor 1
chr3_-_59262825	0.347	ENSMUST00000050360.7	P2ry12	purinergic receptor P2Y, G-protein coupled 12
chr5_+_42067960	0.340	ENSMUST00000087332.4	Gm16223	predicted gene 16223
chr3_-_138131356	0.328	ENSMUST00000029805.8	Mttp	microsomal triglyceride transfer protein
chr2_+_85037448	0.328	ENSMUST00000168266.1 ENSMUST00000130729.1	Ssrp1	structure specific recognition protein 1
chr2_-_25224653	0.327	ENSMUST00000043584.4	Tubb4b	tubulin, beta 4B class IVB
chr10_+_53337686	0.327	ENSMUST00000046221.6 ENSMUST00000163319.1	Pln	phospholamban
chr13_+_56702983	0.321	ENSMUST00000069557.7 ENSMUST00000109876.1	Smad5	SMAD family member 5
chr1_+_165788681	0.318	ENSMUST00000161971.1 ENSMUST00000178336.1 ENSMUST00000005907.5 ENSMUST00000027849.4	Cd247	CD247 antigen
chr1_-_82586781	0.311	ENSMUST00000087050.5	Col4a4	collagen, type IV, alpha 4
chr11_+_118428493	0.308	ENSMUST00000017590.2	C1qtnf1	C1q and tumor necrosis factor related protein 1
chrX_-_18461371	0.307	ENSMUST00000044188.4	4930578C19Rik	RIKEN cDNA 4930578C19 gene
chrX_-_134111852	0.301	ENSMUST00000033610.6	Nox1	NADPH oxidase 1
chr3_+_79885930	0.300	ENSMUST00000029567.8	Fam198b	family with sequence similarity 198, member B
chr2_+_169633517	0.296	ENSMUST00000109157.1	Tshz2	teashirt zinc finger family member 2
chr15_-_98607611	0.278	ENSMUST00000096224.4	Adcy6	adenylate cyclase 6
chrX_+_150547375	0.268	ENSMUST00000066337.6 ENSMUST00000112715.1	Alas2	aminolevulinic acid synthase 2, erythroid
chr10_+_61648552	0.262	ENSMUST00000020286.6	Ppa1	pyrophosphatase (inorganic) 1
chr2_+_69670100	0.259	ENSMUST00000100050.3	Klhl41	kelch-like 41
chr7_-_44892358	0.253	ENSMUST00000003049.6	Med25	mediator of RNA polymerase II transcription, subunit 25 homolog (yeast)
chr10_+_5593718	0.238	ENSMUST00000051809.8	Myct1	myc target 1
chr9_+_109832998	0.236	ENSMUST00000119376.1 ENSMUST00000122343.1	Nme6	NME/NM23 nucleoside diphosphate kinase 6
chr11_-_94242701	0.232	ENSMUST00000061469.3	Wfikkn2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr11_-_53707269	0.229	ENSMUST00000124352.1 ENSMUST00000020649.7	Rad50	RAD50 homolog (S. cerevisiae)
chr5_+_64812336	0.229	ENSMUST00000166409.1	Klf3	Kruppel-like factor 3 (basic)
chr1_+_165788746	0.223	ENSMUST00000161559.2	Cd247	CD247 antigen
chr10_+_80019621	0.220	ENSMUST00000043311.6	Hmha1	histocompatibility (minor) HA-1
chr9_-_77251871	0.206	ENSMUST00000183955.1	Mlip	muscular LMNA-interacting protein
chr10_+_90576252	0.200	ENSMUST00000182427.1 ENSMUST00000182053.1 ENSMUST00000182113.1	Anks1b	ankyrin repeat and sterile alpha motif domain containing 1B
chr9_-_21963568	0.188	ENSMUST00000006397.5	Epor	erythropoietin receptor
chr10_+_90576708	0.185	ENSMUST00000182430.1 ENSMUST00000182960.1 ENSMUST00000182045.1 ENSMUST00000182083.1	Anks1b	ankyrin repeat and sterile alpha motif domain containing 1B
chr10_-_14718191	0.167	ENSMUST00000020016.4	Gje1	gap junction protein, epsilon 1
chr7_-_99238564	0.166	ENSMUST00000064231.7	Mogat2	monoacylglycerol O-acyltransferase 2
chr4_-_46404224	0.165	ENSMUST00000107764.2	Hemgn	hemogen
chrX_-_60403947	0.164	ENSMUST00000033480.6 ENSMUST00000101527.2	Atp11c	ATPase, class VI, type 11C
chr2_+_169632996	0.153	ENSMUST00000109159.2	Tshz2	teashirt zinc finger family member 2
chr3_+_106113229	0.151	ENSMUST00000079132.5 ENSMUST00000139086.1	Chia	chitinase, acidic
chr11_+_95337012	0.150	ENSMUST00000037502.6	Fam117a	family with sequence similarity 117, member A
chr8_+_46490968	0.146	ENSMUST00000110372.1 ENSMUST00000130563.1	Acsl1	acyl-CoA synthetase long-chain family member 1
chrX_+_99975570	0.140	ENSMUST00000113779.1 ENSMUST00000113776.1 ENSMUST00000113775.1 ENSMUST00000113780.1 ENSMUST00000113778.1 ENSMUST00000113781.1 ENSMUST00000113783.1 ENSMUST00000071453.2 ENSMUST00000113777.1	Eda	ectodysplasin-A
chr2_-_33086366	0.139	ENSMUST00000049618.2	Garnl3	GTPase activating RANGAP domain-like 3
chr3_-_146839365	0.134	ENSMUST00000084614.3	Gm10288	predicted gene 10288
chr10_+_90576570	0.133	ENSMUST00000182786.1 ENSMUST00000182600.1	Anks1b	ankyrin repeat and sterile alpha motif domain containing 1B
chr2_-_33087169	0.120	ENSMUST00000102810.3	Garnl3	GTPase activating RANGAP domain-like 3
chr11_-_26591729	0.115	ENSMUST00000109504.1	Vrk2	vaccinia related kinase 2
chr2_-_121037048	0.112	ENSMUST00000102490.3	Epb4.2	erythrocyte protein band 4.2
chr4_+_43493345	0.108	ENSMUST00000030181.5 ENSMUST00000107922.2	Ccdc107	coiled-coil domain containing 107
chr10_+_90576678	0.082	ENSMUST00000182284.1	Anks1b	ankyrin repeat and sterile alpha motif domain containing 1B
chr1_+_135818593	0.079	ENSMUST00000038760.8	Lad1	ladinin
chr4_+_124802543	0.078	ENSMUST00000138807.1 ENSMUST00000030723.2 ENSMUST00000175875.1	Mtf1	metal response element binding transcription factor 1
chr11_+_118428203	0.071	ENSMUST00000124861.1	C1qtnf1	C1q and tumor necrosis factor related protein 1
chr3_-_94886945	0.071	ENSMUST00000005923.6	Psmb4	proteasome (prosome, macropain) subunit, beta type 4
chr8_+_13037308	0.055	ENSMUST00000063820.5 ENSMUST00000033821.4	F10	coagulation factor X
chr6_-_122609964	0.053	ENSMUST00000032211.4	Gdf3	growth differentiation factor 3
chr9_+_44069421	0.052	ENSMUST00000114830.2	Usp2	ubiquitin specific peptidase 2
chrM_+_14138	0.049	ENSMUST00000082421.1	mt-Cytb	mitochondrially encoded cytochrome b
chr11_+_70639118	0.036	ENSMUST00000055184.6 ENSMUST00000108551.2	Gp1ba	glycoprotein 1b, alpha polypeptide
chr18_-_43477764	0.034	ENSMUST00000057110.9	Eif3j2	eukaryotic translation initiation factor 3, subunit J2
chr6_+_17463927	0.027	ENSMUST00000115442.1	Met	met proto-oncogene
chr2_-_20968881	0.024	ENSMUST00000114594.1	Arhgap21	Rho GTPase activating protein 21
chr10_+_81136534	0.023	ENSMUST00000119606.1 ENSMUST00000146895.1 ENSMUST00000121840.1	Zbtb7a	zinc finger and BTB domain containing 7a
chr3_-_94473591	0.021	ENSMUST00000029785.3	Riiad1	regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1
chrX_+_166238901	0.020	ENSMUST00000112235.1	Gpm6b	glycoprotein m6b
chr14_-_54653616	0.019	ENSMUST00000126166.1 ENSMUST00000141453.1 ENSMUST00000150371.1 ENSMUST00000123875.1 ENSMUST00000022794.7 ENSMUST00000148754.3	Acin1	apoptotic chromatin condensation inducer 1
chr10_+_90576777	0.015	ENSMUST00000183136.1 ENSMUST00000182595.1	Anks1b	ankyrin repeat and sterile alpha motif domain containing 1B
chr8_+_105636509	0.013	ENSMUST00000005841.9	Ctcf	CCCTC-binding factor
chr8_+_4325205	0.012	ENSMUST00000127460.1 ENSMUST00000136191.1 ENSMUST00000069762.9 ENSMUST00000098949.4	Ccl25 Ccl25	chemokine (C-C motif) ligand 25 chemokine (C-C motif) ligand 25
chr1_+_75549581	0.008	ENSMUST00000154101.1	Slc4a3	solute carrier family 4 (anion exchanger), member 3

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.9	5.7	GO:0032650	regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) cardiac cell fate determination(GO:0060913)
0.9	5.5	GO:0001980	regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.6	1.9	GO:0044333	Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.6	2.5	GO:0051933	amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.6	2.9	GO:1903609	negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.6	1.7	GO:0015920	regulation of phosphatidylcholine catabolic process(GO:0010899) lipopolysaccharide transport(GO:0015920)
0.6	6.1	GO:2001214	positive regulation of vasculogenesis(GO:2001214)
0.5	1.6	GO:0071918	urea transmembrane transport(GO:0071918)
0.5	3.7	GO:0001955	blood vessel maturation(GO:0001955)
0.5	3.4	GO:0019532	oxalate transport(GO:0019532)
0.5	2.3	GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) positive regulation of blood vessel remodeling(GO:2000504)
0.4	2.5	GO:1904936	cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.4	1.6	GO:0043654	recognition of apoptotic cell(GO:0043654)
0.4	2.6	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.4	2.5	GO:0021913	regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.3	3.5	GO:0070574	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.3	3.6	GO:0070995	toxin metabolic process(GO:0009404) NADPH oxidation(GO:0070995)
0.3	1.7	GO:0002317	plasma cell differentiation(GO:0002317) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.2	1.4	GO:0030299	intestinal cholesterol absorption(GO:0030299)
0.2	1.1	GO:0033632	regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.2	0.9	GO:0010593	negative regulation of lamellipodium assembly(GO:0010593)
0.2	0.5	GO:0003100	regulation of systemic arterial blood pressure by endothelin(GO:0003100) regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.2	0.3	GO:0034196	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.2	1.2	GO:2000857	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1	0.9	GO:0002326	B cell lineage commitment(GO:0002326)
0.1	0.9	GO:0006586	tryptophan metabolic process(GO:0006568) indolalkylamine metabolic process(GO:0006586)
0.1	0.5	GO:0097168	condensed mesenchymal cell proliferation(GO:0072137) mesenchymal stem cell proliferation(GO:0097168)
0.1	0.4	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.1	1.6	GO:0006309	apoptotic DNA fragmentation(GO:0006309)
0.1	1.4	GO:0018065	protein-cofactor linkage(GO:0018065)
0.1	0.3	GO:1904139	microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.1	0.6	GO:0072513	positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1	0.3	GO:0072592	oxygen metabolic process(GO:0072592)
0.1	1.9	GO:0036342	post-anal tail morphogenesis(GO:0036342)
0.1	2.0	GO:0035855	megakaryocyte development(GO:0035855)
0.1	0.4	GO:0071894	histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.1	9.5	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.1	0.3	GO:0035811	negative regulation of urine volume(GO:0035811)
0.1	0.5	GO:0015862	uridine transport(GO:0015862)
0.1	1.0	GO:0046697	decidualization(GO:0046697)
0.1	0.4	GO:0046880	regulation of gonadotropin secretion(GO:0032276) regulation of follicle-stimulating hormone secretion(GO:0046880) follicle-stimulating hormone secretion(GO:0046884)
0.1	0.6	GO:0034242	negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.1	2.0	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.1	0.2	GO:0046462	monoacylglycerol metabolic process(GO:0046462)
0.1	1.2	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.1	0.4	GO:0032261	purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.0	0.1	GO:0061153	trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0	0.6	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0	0.2	GO:0000019	regulation of mitotic recombination(GO:0000019) telomeric 3' overhang formation(GO:0031860)
0.0	0.6	GO:0034377	plasma lipoprotein particle assembly(GO:0034377)
0.0	0.5	GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0	0.5	GO:1900383	regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0	0.3	GO:0032836	glomerular basement membrane development(GO:0032836)
0.0	0.3	GO:0042541	hemoglobin biosynthetic process(GO:0042541)
0.0	0.1	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0	1.5	GO:0021884	forebrain neuron development(GO:0021884)
0.0	0.3	GO:0086023	adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.0	2.5	GO:0030168	platelet activation(GO:0030168)
0.0	0.1	GO:0048859	formation of anatomical boundary(GO:0048859)
0.0	0.8	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.0	0.3	GO:0031272	regulation of pseudopodium assembly(GO:0031272)
0.0	0.2	GO:0006228	UTP biosynthetic process(GO:0006228)
0.0	0.1	GO:0044539	long-chain fatty acid import(GO:0044539)
0.0	0.7	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0	1.5	GO:0021766	hippocampus development(GO:0021766)
0.0	0.3	GO:0035563	positive regulation of chromatin binding(GO:0035563)
0.0	0.4	GO:0070207	protein homotrimerization(GO:0070207)
0.0	0.7	GO:0021799	cerebral cortex radially oriented cell migration(GO:0021799)
0.0	0.2	GO:0045579	phospholipid translocation(GO:0045332) positive regulation of B cell differentiation(GO:0045579)
0.0	0.4	GO:0032728	positive regulation of interferon-beta production(GO:0032728)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	5.5	GO:1990584	cardiac Troponin complex(GO:1990584)
0.6	9.4	GO:0005614	interstitial matrix(GO:0005614)
0.4	2.6	GO:0001674	female germ cell nucleus(GO:0001674)
0.2	2.9	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.2	1.1	GO:0033093	Weibel-Palade body(GO:0033093)
0.2	2.4	GO:0097449	astrocyte projection(GO:0097449)
0.1	0.5	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	2.3	GO:0031528	microvillus membrane(GO:0031528)
0.1	0.4	GO:0043512	inhibin-betaglycan-ActRII complex(GO:0034673) inhibin A complex(GO:0043512)
0.1	0.3	GO:0071438	invadopodium membrane(GO:0071438)
0.1	1.3	GO:0008305	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.1	1.6	GO:0001891	phagocytic cup(GO:0001891)
0.1	0.3	GO:0005587	collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1	0.4	GO:0031467	Cul7-RING ubiquitin ligase complex(GO:0031467)
0.1	0.5	GO:0098533	ATPase dependent transmembrane transport complex(GO:0098533)
0.0	0.2	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.3	GO:0045298	tubulin complex(GO:0045298)
0.0	0.6	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.0	4.2	GO:0043204	perikaryon(GO:0043204)
0.0	0.7	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0	0.9	GO:0000788	nuclear nucleosome(GO:0000788)
0.0	2.6	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	1.1	GO:0001750	photoreceptor outer segment(GO:0001750)
0.0	2.0	GO:0031225	anchored component of membrane(GO:0031225)
0.0	0.2	GO:0005922	connexon complex(GO:0005922)
0.0	0.8	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.8	5.5	GO:0030172	troponin C binding(GO:0030172)
1.3	1.3	GO:0070051	fibrinogen binding(GO:0070051)
0.8	2.5	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.7	3.6	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.6	2.9	GO:0070320	inward rectifier potassium channel inhibitor activity(GO:0070320)
0.6	1.7	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.5	1.6	GO:0004531	deoxyribonuclease II activity(GO:0004531)
0.4	10.4	GO:0001968	fibronectin binding(GO:0001968)
0.3	1.6	GO:0015265	urea channel activity(GO:0015265)
0.3	1.9	GO:0016936	galactoside binding(GO:0016936)
0.3	3.4	GO:0019531	secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.3	0.9	GO:0004510	tryptophan 5-monooxygenase activity(GO:0004510)
0.2	1.4	GO:0004852	uroporphyrinogen-III synthase activity(GO:0004852)
0.2	1.6	GO:0001849	complement component C1q binding(GO:0001849)
0.2	0.9	GO:0004921	interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.2	2.6	GO:0045294	alpha-catenin binding(GO:0045294)
0.2	0.8	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.2	0.5	GO:0004517	nitric-oxide synthase activity(GO:0004517)
0.2	5.7	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.1	0.9	GO:0070644	vitamin D response element binding(GO:0070644)
0.1	3.5	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.1	0.4	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1	0.4	GO:0004875	complement receptor activity(GO:0004875)
0.1	2.0	GO:0005540	hyaluronic acid binding(GO:0005540)
0.1	1.1	GO:0019865	immunoglobulin binding(GO:0019865)
0.1	0.3	GO:0030171	voltage-gated proton channel activity(GO:0030171)
0.1	0.9	GO:0051022	Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1	0.3	GO:0016748	succinyltransferase activity(GO:0016748)
0.1	1.6	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.1	0.9	GO:0070700	BMP receptor binding(GO:0070700)
0.1	1.9	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.1	0.9	GO:0004806	triglyceride lipase activity(GO:0004806)
0.1	0.2	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.1	0.3	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.1	0.4	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.3	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.1	GO:0043758	acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.0	0.3	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.4	GO:0034711	inhibin binding(GO:0034711)
0.0	0.8	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0	0.2	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.0	1.9	GO:0005179	hormone activity(GO:0005179)
0.0	2.4	GO:0035591	signaling adaptor activity(GO:0035591)
0.0	1.7	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	0.8	GO:0005112	Notch binding(GO:0005112)
0.0	0.8	GO:0005272	sodium channel activity(GO:0005272)
0.0	3.9	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	2.0	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0	0.2	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.5	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	0.3	GO:0034185	apolipoprotein binding(GO:0034185)
0.0	0.6	GO:0050699	WW domain binding(GO:0050699)
0.0	0.3	GO:0046965	retinoid X receptor binding(GO:0046965)
0.0	0.4	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.0	0.5	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.5	GO:1990782	protein tyrosine kinase binding(GO:1990782)
0.0	0.8	GO:0019843	rRNA binding(GO:0019843)
0.0	6.7	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.9	PID_WNT_CANONICAL_PATHWAY	Canonical Wnt signaling pathway
0.1	1.3	PID_INTEGRIN_CS_PATHWAY	Integrin family cell surface interactions
0.1	6.6	PID_MYC_ACTIV_PATHWAY	Validated targets of C-MYC transcriptional activation
0.1	1.8	NABA_PROTEOGLYCANS	Genes encoding proteoglycans
0.0	2.0	PID_EPO_PATHWAY	EPO signaling pathway
0.0	6.0	NABA_SECRETED_FACTORS	Genes encoding secreted soluble factors
0.0	0.9	PID_P38_MK2_PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	1.9	PID_BETA_CATENIN_NUC_PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.5	PID_IL12_STAT4_PATHWAY	IL12 signaling mediated by STAT4
0.0	0.5	PID_FRA_PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	1.0	PID_TAP63_PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.6	ST_WNT_BETA_CATENIN_PATHWAY	Wnt/beta-catenin Pathway
0.0	0.3	PID_LPA4_PATHWAY	LPA4-mediated signaling events
0.0	1.9	NABA_ECM_AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	0.3	ST_MYOCYTE_AD_PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	5.7	REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.2	3.5	REACTOME_ZINC_TRANSPORTERS	Genes involved in Zinc transporters
0.2	2.4	REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.2	4.0	REACTOME_STRIATED_MUSCLE_CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	2.0	REACTOME_CS_DS_DEGRADATION	Genes involved in CS/DS degradation
0.1	3.6	REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.1	6.3	REACTOME_LIPID_DIGESTION_MOBILIZATION_AND_TRANSPORT	Genes involved in Lipid digestion, mobilization, and transport
0.1	1.8	REACTOME_REGULATION_OF_KIT_SIGNALING	Genes involved in Regulation of KIT signaling
0.1	0.4	REACTOME_GLYCOPROTEIN_HORMONES	Genes involved in Glycoprotein hormones
0.1	0.5	REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1	0.9	REACTOME_AMINE_DERIVED_HORMONES	Genes involved in Amine-derived hormones
0.1	1.6	REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.1	2.5	REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.3	REACTOME_P2Y_RECEPTORS	Genes involved in P2Y receptors
0.0	0.8	REACTOME_METABOLISM_OF_PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.3	REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	1.0	REACTOME_ELONGATION_ARREST_AND_RECOVERY	Genes involved in Elongation arrest and recovery
0.0	0.9	REACTOME_OTHER_SEMAPHORIN_INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	3.2	REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	1.5	REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.5	REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.5	REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.2	REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.4	REACTOME_PURINE_SALVAGE	Genes involved in Purine salvage
0.0	0.3	REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.1	REACTOME_INTRINSIC_PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.5	REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.3	REACTOME_TRNA_AMINOACYLATION	Genes involved in tRNA Aminoacylation

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