Motif ID: Gata3
Z-value: 1.630
Transcription factors associated with Gata3:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Gata3 | ENSMUSG00000015619.10 | Gata3 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Gata3 | mm10_v2_chr2_-_9878580_9878607 | -0.25 | 7.1e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.7 | 18.7 | GO:0060032 | notochord regression(GO:0060032) |
| 3.6 | 18.2 | GO:0015671 | oxygen transport(GO:0015671) |
| 3.0 | 20.8 | GO:2001199 | negative regulation of dendritic cell differentiation(GO:2001199) |
| 2.3 | 9.0 | GO:0003365 | establishment of cell polarity involved in ameboidal cell migration(GO:0003365) |
| 1.9 | 5.6 | GO:0001869 | regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869) |
| 1.6 | 6.4 | GO:0070829 | heterochromatin maintenance(GO:0070829) |
| 1.3 | 6.5 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
| 1.2 | 13.1 | GO:2000741 | positive regulation of mesenchymal stem cell differentiation(GO:2000741) |
| 1.2 | 7.0 | GO:0021797 | forebrain anterior/posterior pattern specification(GO:0021797) |
| 1.0 | 5.2 | GO:0007223 | Wnt signaling pathway, calcium modulating pathway(GO:0007223) |
| 0.9 | 0.9 | GO:0032916 | positive regulation of transforming growth factor beta3 production(GO:0032916) |
| 0.9 | 6.4 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
| 0.9 | 5.3 | GO:0003383 | apical constriction(GO:0003383) |
| 0.8 | 3.4 | GO:0002069 | columnar/cuboidal epithelial cell maturation(GO:0002069) |
| 0.8 | 9.3 | GO:0060539 | diaphragm development(GO:0060539) |
| 0.8 | 2.5 | GO:0033159 | negative regulation of protein import into nucleus, translocation(GO:0033159) |
| 0.8 | 4.8 | GO:0071883 | activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) |
| 0.8 | 2.4 | GO:1900275 | negative regulation of phospholipase C activity(GO:1900275) |
| 0.8 | 9.0 | GO:2001269 | positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269) |
| 0.7 | 4.5 | GO:0030643 | cellular phosphate ion homeostasis(GO:0030643) phosphate ion transmembrane transport(GO:0035435) cellular trivalent inorganic anion homeostasis(GO:0072502) |
| 0.7 | 2.2 | GO:0006546 | glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464) |
| 0.7 | 3.5 | GO:1903715 | regulation of aerobic respiration(GO:1903715) |
| 0.7 | 2.8 | GO:1905167 | positive regulation of lysosomal protein catabolic process(GO:1905167) |
| 0.7 | 2.1 | GO:0070650 | actin filament bundle distribution(GO:0070650) |
| 0.7 | 2.7 | GO:2001045 | closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045) |
| 0.7 | 2.6 | GO:0009414 | response to water deprivation(GO:0009414) |
| 0.6 | 2.6 | GO:1900220 | semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220) |
| 0.6 | 1.9 | GO:0098528 | skeletal muscle fiber differentiation(GO:0098528) |
| 0.6 | 8.7 | GO:0007213 | G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) |
| 0.6 | 1.8 | GO:0019046 | release from viral latency(GO:0019046) |
| 0.6 | 1.8 | GO:0044028 | DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029) |
| 0.6 | 2.3 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
| 0.6 | 1.7 | GO:0043456 | regulation of pentose-phosphate shunt(GO:0043456) |
| 0.6 | 1.7 | GO:0034241 | positive regulation of macrophage fusion(GO:0034241) |
| 0.5 | 9.2 | GO:0006085 | acetyl-CoA biosynthetic process(GO:0006085) |
| 0.5 | 1.5 | GO:0044778 | meiotic DNA integrity checkpoint(GO:0044778) |
| 0.5 | 6.0 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
| 0.5 | 8.1 | GO:0035563 | positive regulation of chromatin binding(GO:0035563) |
| 0.5 | 3.2 | GO:1904217 | regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222) |
| 0.5 | 1.8 | GO:0042414 | epinephrine metabolic process(GO:0042414) |
| 0.5 | 4.1 | GO:1900194 | negative regulation of oocyte maturation(GO:1900194) |
| 0.4 | 1.3 | GO:0035574 | histone H4-K20 demethylation(GO:0035574) |
| 0.4 | 1.3 | GO:2000508 | regulation of dendritic cell chemotaxis(GO:2000508) |
| 0.4 | 3.0 | GO:0031508 | pericentric heterochromatin assembly(GO:0031508) |
| 0.4 | 2.1 | GO:0046684 | response to pyrethroid(GO:0046684) |
| 0.4 | 3.4 | GO:1903847 | regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849) |
| 0.4 | 5.8 | GO:0060013 | righting reflex(GO:0060013) |
| 0.4 | 2.5 | GO:0001842 | neural fold formation(GO:0001842) |
| 0.4 | 1.6 | GO:0051643 | endoplasmic reticulum localization(GO:0051643) |
| 0.4 | 1.6 | GO:2000211 | regulation of glutamate metabolic process(GO:2000211) |
| 0.4 | 2.0 | GO:0007089 | traversing start control point of mitotic cell cycle(GO:0007089) |
| 0.4 | 2.4 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
| 0.4 | 5.4 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
| 0.4 | 1.5 | GO:1903294 | axon target recognition(GO:0007412) regulation of glutamate secretion, neurotransmission(GO:1903294) positive regulation of glutamate secretion, neurotransmission(GO:1903296) |
| 0.4 | 1.5 | GO:0055099 | response to high density lipoprotein particle(GO:0055099) |
| 0.4 | 1.1 | GO:0072139 | glomerular parietal epithelial cell differentiation(GO:0072139) |
| 0.4 | 1.1 | GO:0071211 | protein targeting to vacuole involved in autophagy(GO:0071211) |
| 0.4 | 1.5 | GO:0030860 | regulation of polarized epithelial cell differentiation(GO:0030860) |
| 0.4 | 1.1 | GO:1904058 | positive regulation of sensory perception of pain(GO:1904058) |
| 0.4 | 2.9 | GO:0048102 | autophagic cell death(GO:0048102) |
| 0.4 | 0.7 | GO:0070212 | protein poly-ADP-ribosylation(GO:0070212) |
| 0.4 | 1.4 | GO:0060316 | positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) |
| 0.3 | 0.7 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
| 0.3 | 2.7 | GO:0072615 | interleukin-17 secretion(GO:0072615) |
| 0.3 | 1.0 | GO:0035523 | protein K29-linked deubiquitination(GO:0035523) protein K6-linked deubiquitination(GO:0044313) |
| 0.3 | 1.0 | GO:0030327 | prenylated protein catabolic process(GO:0030327) |
| 0.3 | 2.6 | GO:0071802 | negative regulation of podosome assembly(GO:0071802) |
| 0.3 | 1.9 | GO:0098964 | dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964) |
| 0.3 | 1.2 | GO:2001274 | negative regulation of glucose import in response to insulin stimulus(GO:2001274) |
| 0.3 | 1.8 | GO:0014874 | response to stimulus involved in regulation of muscle adaptation(GO:0014874) |
| 0.3 | 2.7 | GO:0002536 | respiratory burst involved in inflammatory response(GO:0002536) |
| 0.3 | 1.5 | GO:0035864 | response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865) |
| 0.3 | 1.5 | GO:0042891 | antibiotic transport(GO:0042891) dipeptide transport(GO:0042938) |
| 0.3 | 1.2 | GO:0072385 | minus-end-directed organelle transport along microtubule(GO:0072385) |
| 0.3 | 1.2 | GO:0032289 | central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912) |
| 0.3 | 3.2 | GO:0014883 | transition between fast and slow fiber(GO:0014883) |
| 0.3 | 3.2 | GO:0097151 | positive regulation of inhibitory postsynaptic potential(GO:0097151) |
| 0.3 | 1.4 | GO:0035617 | stress granule disassembly(GO:0035617) plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386) regulation of voltage-gated sodium channel activity(GO:1905150) |
| 0.3 | 4.0 | GO:2001223 | negative regulation of neuron migration(GO:2001223) |
| 0.3 | 0.8 | GO:0036233 | glycine import(GO:0036233) |
| 0.3 | 1.7 | GO:0045198 | establishment of epithelial cell apical/basal polarity(GO:0045198) |
| 0.3 | 2.5 | GO:0036371 | T-tubule organization(GO:0033292) protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) |
| 0.3 | 1.1 | GO:0036515 | serotonergic neuron axon guidance(GO:0036515) |
| 0.3 | 1.4 | GO:0035616 | histone H2B conserved C-terminal lysine deubiquitination(GO:0035616) |
| 0.3 | 1.3 | GO:0007403 | glial cell fate determination(GO:0007403) |
| 0.3 | 7.8 | GO:0007617 | mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705) |
| 0.3 | 0.5 | GO:0061535 | glutamate secretion, neurotransmission(GO:0061535) |
| 0.3 | 3.7 | GO:0050774 | negative regulation of dendrite morphogenesis(GO:0050774) |
| 0.3 | 1.8 | GO:2000124 | regulation of endocannabinoid signaling pathway(GO:2000124) |
| 0.3 | 1.3 | GO:0036324 | vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) |
| 0.3 | 1.0 | GO:0007056 | spindle assembly involved in female meiosis(GO:0007056) |
| 0.3 | 1.8 | GO:0043568 | positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568) |
| 0.3 | 1.3 | GO:0042535 | positive regulation of tumor necrosis factor biosynthetic process(GO:0042535) |
| 0.2 | 1.5 | GO:0021631 | optic nerve morphogenesis(GO:0021631) |
| 0.2 | 4.4 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
| 0.2 | 0.7 | GO:1900108 | negative regulation of nodal signaling pathway(GO:1900108) |
| 0.2 | 1.0 | GO:0051547 | regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549) |
| 0.2 | 1.1 | GO:2001168 | regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168) |
| 0.2 | 1.1 | GO:1900042 | positive regulation of interleukin-2 secretion(GO:1900042) |
| 0.2 | 9.7 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.2 | 0.7 | GO:0060011 | Sertoli cell proliferation(GO:0060011) |
| 0.2 | 0.9 | GO:0072309 | negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003340) mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis(GO:0072309) regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384) |
| 0.2 | 0.6 | GO:0014042 | positive regulation of neuron maturation(GO:0014042) |
| 0.2 | 0.6 | GO:1904211 | membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211) |
| 0.2 | 1.1 | GO:0038031 | non-canonical Wnt signaling pathway via JNK cascade(GO:0038031) |
| 0.2 | 0.6 | GO:2001015 | G1 to G0 transition involved in cell differentiation(GO:0070315) negative regulation of skeletal muscle cell differentiation(GO:2001015) |
| 0.2 | 1.0 | GO:0051661 | maintenance of centrosome location(GO:0051661) |
| 0.2 | 2.1 | GO:0090315 | negative regulation of protein targeting to membrane(GO:0090315) |
| 0.2 | 5.1 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
| 0.2 | 0.8 | GO:0006663 | platelet activating factor biosynthetic process(GO:0006663) |
| 0.2 | 0.6 | GO:1902396 | protein localization to bicellular tight junction(GO:1902396) |
| 0.2 | 1.0 | GO:0032329 | serine transport(GO:0032329) |
| 0.2 | 0.8 | GO:0046950 | cellular ketone body metabolic process(GO:0046950) |
| 0.2 | 1.6 | GO:1990845 | adaptive thermogenesis(GO:1990845) |
| 0.2 | 0.6 | GO:0015882 | L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904) |
| 0.2 | 6.3 | GO:0007026 | negative regulation of microtubule depolymerization(GO:0007026) |
| 0.2 | 0.7 | GO:0010511 | regulation of phosphatidylinositol biosynthetic process(GO:0010511) |
| 0.2 | 0.4 | GO:0099527 | postsynapse to nucleus signaling pathway(GO:0099527) |
| 0.2 | 0.9 | GO:0071894 | histone H2B conserved C-terminal lysine ubiquitination(GO:0071894) |
| 0.2 | 0.5 | GO:0002014 | vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014) |
| 0.2 | 1.6 | GO:0038203 | TORC2 signaling(GO:0038203) |
| 0.2 | 1.3 | GO:0051461 | protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461) |
| 0.2 | 1.8 | GO:0060689 | cell differentiation involved in salivary gland development(GO:0060689) |
| 0.2 | 2.1 | GO:0090209 | negative regulation of triglyceride metabolic process(GO:0090209) |
| 0.2 | 0.7 | GO:0014012 | peripheral nervous system axon regeneration(GO:0014012) |
| 0.2 | 3.2 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
| 0.2 | 0.3 | GO:0031086 | nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087) |
| 0.2 | 1.2 | GO:0098703 | calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035) |
| 0.2 | 1.5 | GO:0051256 | mitotic spindle midzone assembly(GO:0051256) |
| 0.2 | 0.9 | GO:0006543 | glutamine catabolic process(GO:0006543) |
| 0.2 | 1.5 | GO:0048934 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
| 0.2 | 0.5 | GO:2000642 | negative regulation of early endosome to late endosome transport(GO:2000642) |
| 0.2 | 3.2 | GO:2000171 | negative regulation of dendrite development(GO:2000171) |
| 0.2 | 0.5 | GO:0071929 | alpha-tubulin acetylation(GO:0071929) |
| 0.2 | 0.8 | GO:0045743 | positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743) |
| 0.2 | 0.6 | GO:0060124 | positive regulation of growth hormone secretion(GO:0060124) |
| 0.2 | 2.6 | GO:0010225 | response to UV-C(GO:0010225) |
| 0.2 | 0.5 | GO:1990927 | negative regulation of tumor necrosis factor secretion(GO:1904468) negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927) |
| 0.2 | 0.8 | GO:0061038 | uterus morphogenesis(GO:0061038) |
| 0.2 | 0.5 | GO:0046340 | diacylglycerol catabolic process(GO:0046340) |
| 0.2 | 0.6 | GO:0019919 | peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919) |
| 0.1 | 1.0 | GO:0090160 | Golgi to lysosome transport(GO:0090160) |
| 0.1 | 0.6 | GO:0090298 | mitochondrial DNA repair(GO:0043504) negative regulation of mitochondrial DNA replication(GO:0090298) |
| 0.1 | 1.2 | GO:0048149 | behavioral response to ethanol(GO:0048149) |
| 0.1 | 3.2 | GO:0010763 | positive regulation of fibroblast migration(GO:0010763) |
| 0.1 | 1.0 | GO:0031547 | brain-derived neurotrophic factor receptor signaling pathway(GO:0031547) |
| 0.1 | 1.0 | GO:0098885 | modification of postsynaptic actin cytoskeleton(GO:0098885) |
| 0.1 | 0.3 | GO:0071550 | death-inducing signaling complex assembly(GO:0071550) |
| 0.1 | 2.1 | GO:0045671 | negative regulation of osteoclast differentiation(GO:0045671) |
| 0.1 | 1.1 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 0.1 | 0.8 | GO:0031536 | positive regulation of exit from mitosis(GO:0031536) |
| 0.1 | 2.3 | GO:0046069 | cGMP catabolic process(GO:0046069) |
| 0.1 | 1.2 | GO:0036120 | cellular response to platelet-derived growth factor stimulus(GO:0036120) |
| 0.1 | 0.9 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.1 | 1.3 | GO:0033148 | positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148) |
| 0.1 | 1.4 | GO:0048368 | lateral mesoderm development(GO:0048368) |
| 0.1 | 1.0 | GO:0032926 | negative regulation of activin receptor signaling pathway(GO:0032926) |
| 0.1 | 0.6 | GO:2001013 | epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013) |
| 0.1 | 0.6 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 0.1 | 1.1 | GO:0006104 | succinyl-CoA metabolic process(GO:0006104) |
| 0.1 | 0.4 | GO:1990839 | response to endothelin(GO:1990839) |
| 0.1 | 3.0 | GO:0010758 | regulation of macrophage chemotaxis(GO:0010758) |
| 0.1 | 0.8 | GO:0001880 | Mullerian duct regression(GO:0001880) |
| 0.1 | 0.7 | GO:0097473 | cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473) |
| 0.1 | 0.2 | GO:0035188 | blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684) |
| 0.1 | 1.2 | GO:0060712 | spongiotrophoblast layer development(GO:0060712) |
| 0.1 | 0.6 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
| 0.1 | 0.6 | GO:0018242 | protein O-linked glycosylation via serine(GO:0018242) |
| 0.1 | 0.9 | GO:0032074 | negative regulation of nuclease activity(GO:0032074) |
| 0.1 | 0.3 | GO:0016598 | protein arginylation(GO:0016598) |
| 0.1 | 0.5 | GO:0018125 | peptidyl-cysteine methylation(GO:0018125) |
| 0.1 | 0.5 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.1 | 1.1 | GO:0006620 | posttranslational protein targeting to membrane(GO:0006620) |
| 0.1 | 0.6 | GO:0042866 | pyruvate biosynthetic process(GO:0042866) |
| 0.1 | 0.8 | GO:0070863 | positive regulation of protein exit from endoplasmic reticulum(GO:0070863) |
| 0.1 | 1.5 | GO:0021860 | pyramidal neuron development(GO:0021860) |
| 0.1 | 0.4 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
| 0.1 | 1.3 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
| 0.1 | 0.5 | GO:0050912 | detection of chemical stimulus involved in sensory perception(GO:0050907) detection of chemical stimulus involved in sensory perception of taste(GO:0050912) |
| 0.1 | 0.2 | GO:0060018 | astrocyte fate commitment(GO:0060018) |
| 0.1 | 0.7 | GO:0072321 | chaperone-mediated protein transport(GO:0072321) |
| 0.1 | 0.4 | GO:0098908 | regulation of neuronal action potential(GO:0098908) |
| 0.1 | 1.3 | GO:0045199 | maintenance of epithelial cell apical/basal polarity(GO:0045199) |
| 0.1 | 0.2 | GO:0010571 | positive regulation of nuclear cell cycle DNA replication(GO:0010571) |
| 0.1 | 0.5 | GO:0097167 | circadian regulation of translation(GO:0097167) |
| 0.1 | 0.6 | GO:0051353 | positive regulation of oxidoreductase activity(GO:0051353) |
| 0.1 | 0.7 | GO:1901029 | negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029) |
| 0.1 | 0.4 | GO:0070317 | negative regulation of G0 to G1 transition(GO:0070317) |
| 0.1 | 0.8 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 0.1 | 1.8 | GO:0051450 | myoblast proliferation(GO:0051450) |
| 0.1 | 0.3 | GO:0006667 | sphinganine metabolic process(GO:0006667) |
| 0.1 | 1.8 | GO:2001224 | positive regulation of neuron migration(GO:2001224) |
| 0.1 | 0.8 | GO:0061088 | sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088) |
| 0.1 | 1.3 | GO:0070914 | UV-damage excision repair(GO:0070914) |
| 0.1 | 0.9 | GO:0036123 | histone H3-K9 dimethylation(GO:0036123) |
| 0.1 | 2.1 | GO:0044783 | mitotic G1 DNA damage checkpoint(GO:0031571) G1 DNA damage checkpoint(GO:0044783) |
| 0.1 | 0.3 | GO:0016056 | photoreceptor cell morphogenesis(GO:0008594) rhodopsin mediated signaling pathway(GO:0016056) post-embryonic retina morphogenesis in camera-type eye(GO:0060060) |
| 0.1 | 0.7 | GO:0050884 | neuromuscular process controlling posture(GO:0050884) |
| 0.1 | 1.9 | GO:0090036 | regulation of protein kinase C signaling(GO:0090036) |
| 0.1 | 0.7 | GO:0031848 | protection from non-homologous end joining at telomere(GO:0031848) |
| 0.1 | 0.7 | GO:0031507 | heterochromatin assembly(GO:0031507) |
| 0.1 | 1.5 | GO:0006353 | DNA-templated transcription, termination(GO:0006353) |
| 0.1 | 3.3 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
| 0.1 | 0.9 | GO:0014051 | gamma-aminobutyric acid secretion(GO:0014051) |
| 0.1 | 0.1 | GO:0021836 | cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) |
| 0.1 | 0.7 | GO:0070986 | left/right axis specification(GO:0070986) |
| 0.1 | 0.6 | GO:0086036 | regulation of cardiac muscle cell membrane potential(GO:0086036) |
| 0.1 | 1.0 | GO:0010950 | positive regulation of endopeptidase activity(GO:0010950) |
| 0.1 | 0.8 | GO:0007413 | axonal fasciculation(GO:0007413) |
| 0.1 | 3.0 | GO:0000460 | maturation of 5.8S rRNA(GO:0000460) |
| 0.1 | 0.3 | GO:0070561 | vitamin D receptor signaling pathway(GO:0070561) |
| 0.1 | 0.3 | GO:0006780 | uroporphyrinogen III biosynthetic process(GO:0006780) |
| 0.1 | 0.3 | GO:0070314 | G1 to G0 transition(GO:0070314) |
| 0.1 | 0.2 | GO:0060971 | embryonic heart tube left/right pattern formation(GO:0060971) |
| 0.1 | 2.7 | GO:0016601 | Rac protein signal transduction(GO:0016601) |
| 0.1 | 2.8 | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184) |
| 0.1 | 0.7 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.1 | 0.7 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
| 0.1 | 3.0 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.1 | 0.4 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
| 0.1 | 1.1 | GO:0045947 | negative regulation of translational initiation(GO:0045947) |
| 0.1 | 0.5 | GO:0002002 | regulation of angiotensin levels in blood(GO:0002002) |
| 0.1 | 0.8 | GO:0097067 | cellular response to thyroid hormone stimulus(GO:0097067) |
| 0.1 | 1.2 | GO:0016188 | synaptic vesicle maturation(GO:0016188) |
| 0.1 | 0.5 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 0.1 | 0.5 | GO:1902035 | positive regulation of hematopoietic stem cell proliferation(GO:1902035) |
| 0.1 | 0.7 | GO:0090385 | phagosome-lysosome fusion(GO:0090385) |
| 0.1 | 1.8 | GO:0014046 | dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059) |
| 0.1 | 1.6 | GO:0010591 | regulation of lamellipodium assembly(GO:0010591) |
| 0.1 | 0.9 | GO:0043046 | DNA methylation involved in gamete generation(GO:0043046) |
| 0.1 | 1.1 | GO:0002920 | regulation of humoral immune response(GO:0002920) |
| 0.1 | 5.4 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.1 | 2.6 | GO:0031648 | protein destabilization(GO:0031648) |
| 0.1 | 0.4 | GO:0071955 | recycling endosome to Golgi transport(GO:0071955) |
| 0.1 | 4.1 | GO:0080171 | lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171) |
| 0.1 | 0.3 | GO:0050908 | detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962) |
| 0.1 | 1.6 | GO:0060479 | lung cell differentiation(GO:0060479) lung epithelial cell differentiation(GO:0060487) |
| 0.1 | 0.5 | GO:0030263 | apoptotic chromosome condensation(GO:0030263) |
| 0.1 | 0.7 | GO:0023019 | signal transduction involved in regulation of gene expression(GO:0023019) |
| 0.1 | 1.1 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 0.1 | 0.3 | GO:0036438 | maintenance of lens transparency(GO:0036438) |
| 0.1 | 1.1 | GO:0060218 | hematopoietic stem cell differentiation(GO:0060218) |
| 0.1 | 0.7 | GO:1900037 | regulation of cellular response to hypoxia(GO:1900037) |
| 0.1 | 0.4 | GO:0030718 | germ-line stem cell population maintenance(GO:0030718) |
| 0.1 | 0.3 | GO:0042796 | snRNA transcription from RNA polymerase III promoter(GO:0042796) |
| 0.1 | 0.9 | GO:0035459 | cargo loading into vesicle(GO:0035459) cargo loading into COPII-coated vesicle(GO:0090110) |
| 0.1 | 0.5 | GO:0090043 | regulation of tubulin deacetylation(GO:0090043) |
| 0.1 | 1.7 | GO:0010569 | regulation of double-strand break repair via homologous recombination(GO:0010569) |
| 0.1 | 0.7 | GO:0051016 | barbed-end actin filament capping(GO:0051016) |
| 0.1 | 0.5 | GO:0010835 | regulation of protein ADP-ribosylation(GO:0010835) |
| 0.1 | 0.4 | GO:0043401 | steroid hormone mediated signaling pathway(GO:0043401) |
| 0.1 | 0.8 | GO:0043984 | histone H4-K16 acetylation(GO:0043984) |
| 0.1 | 0.2 | GO:2000304 | positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304) |
| 0.1 | 0.4 | GO:0071732 | cellular response to nitric oxide(GO:0071732) |
| 0.1 | 0.5 | GO:0007220 | Notch receptor processing(GO:0007220) |
| 0.1 | 0.7 | GO:0006833 | water transport(GO:0006833) |
| 0.1 | 0.2 | GO:1903800 | positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800) |
| 0.1 | 0.3 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
| 0.1 | 0.2 | GO:1900864 | mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864) |
| 0.1 | 3.4 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
| 0.1 | 0.5 | GO:0014029 | neural crest formation(GO:0014029) |
| 0.1 | 0.3 | GO:0051045 | negative regulation of membrane protein ectodomain proteolysis(GO:0051045) |
| 0.1 | 0.4 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
| 0.1 | 0.7 | GO:0006654 | phosphatidic acid biosynthetic process(GO:0006654) |
| 0.1 | 0.2 | GO:1904715 | negative regulation of chaperone-mediated autophagy(GO:1904715) |
| 0.1 | 0.4 | GO:0030242 | pexophagy(GO:0030242) |
| 0.0 | 0.2 | GO:0010796 | regulation of multivesicular body size(GO:0010796) |
| 0.0 | 4.5 | GO:0072332 | intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332) |
| 0.0 | 1.8 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
| 0.0 | 3.2 | GO:0051782 | negative regulation of cell division(GO:0051782) |
| 0.0 | 0.6 | GO:0032366 | intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367) |
| 0.0 | 0.2 | GO:0051182 | coenzyme transport(GO:0051182) |
| 0.0 | 0.5 | GO:1903432 | regulation of TORC1 signaling(GO:1903432) |
| 0.0 | 0.4 | GO:0035520 | monoubiquitinated protein deubiquitination(GO:0035520) |
| 0.0 | 0.4 | GO:1903861 | regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861) |
| 0.0 | 0.1 | GO:0048143 | astrocyte activation(GO:0048143) |
| 0.0 | 0.9 | GO:0032967 | positive regulation of collagen biosynthetic process(GO:0032967) |
| 0.0 | 0.4 | GO:0006013 | mannose metabolic process(GO:0006013) |
| 0.0 | 0.3 | GO:2000491 | positive regulation of hepatic stellate cell activation(GO:2000491) |
| 0.0 | 1.7 | GO:0009712 | catecholamine metabolic process(GO:0006584) catechol-containing compound metabolic process(GO:0009712) |
| 0.0 | 0.2 | GO:0052428 | modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428) |
| 0.0 | 0.3 | GO:0042403 | thyroid hormone metabolic process(GO:0042403) |
| 0.0 | 0.3 | GO:0051225 | spindle assembly(GO:0051225) |
| 0.0 | 0.3 | GO:1990573 | potassium ion import across plasma membrane(GO:1990573) |
| 0.0 | 0.3 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
| 0.0 | 0.1 | GO:0070488 | regulation of integrin biosynthetic process(GO:0045113) neutrophil aggregation(GO:0070488) |
| 0.0 | 0.3 | GO:0034242 | negative regulation of syncytium formation by plasma membrane fusion(GO:0034242) |
| 0.0 | 1.5 | GO:0032007 | negative regulation of TOR signaling(GO:0032007) |
| 0.0 | 0.6 | GO:0035721 | intraciliary retrograde transport(GO:0035721) |
| 0.0 | 1.1 | GO:0007608 | sensory perception of smell(GO:0007608) |
| 0.0 | 1.4 | GO:0070830 | bicellular tight junction assembly(GO:0070830) |
| 0.0 | 0.6 | GO:0071786 | endoplasmic reticulum tubular network organization(GO:0071786) |
| 0.0 | 0.9 | GO:0035036 | binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) |
| 0.0 | 0.3 | GO:0021521 | ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573) |
| 0.0 | 0.4 | GO:1990403 | embryonic brain development(GO:1990403) |
| 0.0 | 0.5 | GO:0046597 | negative regulation of viral entry into host cell(GO:0046597) negative regulation of viral release from host cell(GO:1902187) |
| 0.0 | 0.4 | GO:0046697 | decidualization(GO:0046697) |
| 0.0 | 0.1 | GO:0090204 | protein localization to nuclear pore(GO:0090204) negative regulation of vascular endothelial growth factor production(GO:1904046) |
| 0.0 | 0.4 | GO:0007602 | phototransduction(GO:0007602) |
| 0.0 | 0.2 | GO:0046322 | negative regulation of fatty acid oxidation(GO:0046322) |
| 0.0 | 0.2 | GO:0046600 | negative regulation of centriole replication(GO:0046600) |
| 0.0 | 0.0 | GO:1903897 | regulation of PERK-mediated unfolded protein response(GO:1903897) negative regulation of PERK-mediated unfolded protein response(GO:1903898) |
| 0.0 | 0.7 | GO:0002053 | positive regulation of mesenchymal cell proliferation(GO:0002053) |
| 0.0 | 0.2 | GO:0032264 | IMP salvage(GO:0032264) |
| 0.0 | 0.5 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
| 0.0 | 0.3 | GO:0018065 | protein-cofactor linkage(GO:0018065) |
| 0.0 | 1.1 | GO:0060612 | adipose tissue development(GO:0060612) |
| 0.0 | 0.3 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 0.0 | 0.2 | GO:0006621 | protein retention in ER lumen(GO:0006621) |
| 0.0 | 0.6 | GO:0032212 | positive regulation of telomere maintenance via telomerase(GO:0032212) |
| 0.0 | 0.2 | GO:0071361 | cellular response to ethanol(GO:0071361) |
| 0.0 | 0.2 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.0 | 0.3 | GO:0031584 | activation of phospholipase D activity(GO:0031584) |
| 0.0 | 0.8 | GO:0031572 | G2 DNA damage checkpoint(GO:0031572) |
| 0.0 | 0.4 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
| 0.0 | 1.1 | GO:0046580 | negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058) |
| 0.0 | 0.4 | GO:0048147 | negative regulation of fibroblast proliferation(GO:0048147) |
| 0.0 | 1.3 | GO:0043044 | ATP-dependent chromatin remodeling(GO:0043044) |
| 0.0 | 0.4 | GO:0030728 | ovulation(GO:0030728) |
| 0.0 | 2.6 | GO:0007050 | cell cycle arrest(GO:0007050) |
| 0.0 | 0.2 | GO:0035428 | hexose transmembrane transport(GO:0035428) |
| 0.0 | 0.6 | GO:0006301 | postreplication repair(GO:0006301) |
| 0.0 | 0.7 | GO:1901184 | regulation of ERBB signaling pathway(GO:1901184) |
| 0.0 | 0.1 | GO:0016068 | regulation of type I hypersensitivity(GO:0001810) positive regulation of type I hypersensitivity(GO:0001812) type I hypersensitivity(GO:0016068) |
| 0.0 | 0.2 | GO:0097105 | presynaptic membrane assembly(GO:0097105) |
| 0.0 | 0.7 | GO:0015988 | energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) |
| 0.0 | 0.1 | GO:0014816 | skeletal muscle satellite cell differentiation(GO:0014816) |
| 0.0 | 0.7 | GO:0007585 | respiratory gaseous exchange(GO:0007585) |
| 0.0 | 0.2 | GO:0001522 | pseudouridine synthesis(GO:0001522) |
| 0.0 | 0.1 | GO:0044861 | protein transport into plasma membrane raft(GO:0044861) |
| 0.0 | 0.2 | GO:0090205 | positive regulation of cholesterol biosynthetic process(GO:0045542) positive regulation of cholesterol metabolic process(GO:0090205) |
| 0.0 | 0.5 | GO:0043550 | regulation of lipid kinase activity(GO:0043550) |
| 0.0 | 0.6 | GO:0021692 | cerebellar Purkinje cell layer morphogenesis(GO:0021692) |
| 0.0 | 0.8 | GO:0045670 | regulation of osteoclast differentiation(GO:0045670) |
| 0.0 | 0.2 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 0.0 | 0.7 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.0 | 0.3 | GO:0006582 | melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438) |
| 0.0 | 0.3 | GO:0061013 | regulation of mRNA catabolic process(GO:0061013) positive regulation of mRNA catabolic process(GO:0061014) |
| 0.0 | 1.9 | GO:0048515 | spermatid differentiation(GO:0048515) |
| 0.0 | 0.2 | GO:0021942 | radial glia guided migration of Purkinje cell(GO:0021942) |
| 0.0 | 0.7 | GO:0061001 | regulation of dendritic spine morphogenesis(GO:0061001) |
| 0.0 | 0.3 | GO:0030033 | microvillus assembly(GO:0030033) |
| 0.0 | 0.3 | GO:0042439 | ethanolamine-containing compound metabolic process(GO:0042439) |
| 0.0 | 0.5 | GO:0048013 | ephrin receptor signaling pathway(GO:0048013) |
| 0.0 | 0.2 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.0 | 0.7 | GO:0031122 | cytoplasmic microtubule organization(GO:0031122) |
| 0.0 | 0.3 | GO:0006096 | glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757) |
| 0.0 | 0.3 | GO:0010800 | positive regulation of peptidyl-threonine phosphorylation(GO:0010800) |
| 0.0 | 0.4 | GO:0007099 | centriole replication(GO:0007099) |
| 0.0 | 0.7 | GO:0030521 | androgen receptor signaling pathway(GO:0030521) |
| 0.0 | 0.1 | GO:0033762 | response to glucagon(GO:0033762) |
| 0.0 | 0.7 | GO:0043666 | regulation of phosphoprotein phosphatase activity(GO:0043666) |
| 0.0 | 0.4 | GO:0033235 | positive regulation of protein sumoylation(GO:0033235) |
| 0.0 | 0.0 | GO:0042117 | monocyte activation(GO:0042117) |
| 0.0 | 0.5 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.0 | 0.1 | GO:0051697 | protein delipidation(GO:0051697) |
| 0.0 | 0.4 | GO:0030316 | osteoclast differentiation(GO:0030316) |
| 0.0 | 0.3 | GO:0007338 | single fertilization(GO:0007338) |
| 0.0 | 1.0 | GO:0006342 | chromatin silencing(GO:0006342) |
| 0.0 | 0.1 | GO:0000712 | resolution of meiotic recombination intermediates(GO:0000712) |
| 0.0 | 0.0 | GO:0018243 | protein O-linked glycosylation via threonine(GO:0018243) |
| 0.0 | 0.1 | GO:0061622 | glycolytic process through glucose-1-phosphate(GO:0061622) |
| 0.0 | 0.5 | GO:0043525 | positive regulation of neuron apoptotic process(GO:0043525) |
| 0.0 | 0.0 | GO:0042713 | brain renin-angiotensin system(GO:0002035) sperm ejaculation(GO:0042713) |
| 0.0 | 0.6 | GO:0051865 | protein autoubiquitination(GO:0051865) |
| 0.0 | 0.1 | GO:0035269 | protein O-linked mannosylation(GO:0035269) |
| 0.0 | 0.3 | GO:0051123 | RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) |
| 0.0 | 0.5 | GO:0007041 | lysosomal transport(GO:0007041) |
| 0.0 | 0.1 | GO:0090031 | positive regulation of steroid hormone biosynthetic process(GO:0090031) |
| 0.0 | 0.4 | GO:0046329 | negative regulation of JNK cascade(GO:0046329) |
| 0.0 | 0.1 | GO:0061635 | regulation of protein complex stability(GO:0061635) |
| 0.0 | 0.4 | GO:0003382 | epithelial cell morphogenesis(GO:0003382) |
| 0.0 | 0.3 | GO:0048144 | fibroblast proliferation(GO:0048144) |
| 0.0 | 0.1 | GO:2000095 | regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095) |
| 0.0 | 0.6 | GO:0035383 | acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383) |
| 0.0 | 0.2 | GO:0006825 | copper ion transport(GO:0006825) |
| 0.0 | 0.0 | GO:0090370 | negative regulation of cholesterol efflux(GO:0090370) |
| 0.0 | 0.2 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.0 | 0.3 | GO:0032006 | regulation of TOR signaling(GO:0032006) |
| 0.0 | 0.2 | GO:1902653 | cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653) |
| 0.0 | 0.2 | GO:0006383 | transcription from RNA polymerase III promoter(GO:0006383) |
| 0.0 | 0.7 | GO:1903749 | positive regulation of establishment of protein localization to mitochondrion(GO:1903749) positive regulation of protein targeting to mitochondrion(GO:1903955) |
| 0.0 | 0.3 | GO:0006368 | transcription elongation from RNA polymerase II promoter(GO:0006368) |
| 0.0 | 0.1 | GO:0048096 | chromatin-mediated maintenance of transcription(GO:0048096) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.7 | 13.7 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 1.5 | 19.0 | GO:0097542 | ciliary tip(GO:0097542) |
| 0.8 | 2.5 | GO:0044302 | dentate gyrus mossy fiber(GO:0044302) |
| 0.7 | 1.4 | GO:0071149 | TEAD-2-YAP complex(GO:0071149) |
| 0.6 | 2.5 | GO:0090537 | CERF complex(GO:0090537) |
| 0.6 | 1.8 | GO:0045009 | melanosome membrane(GO:0033162) chitosome(GO:0045009) |
| 0.6 | 1.8 | GO:0005943 | phosphatidylinositol 3-kinase complex, class IA(GO:0005943) |
| 0.6 | 2.3 | GO:0071148 | TEAD-1-YAP complex(GO:0071148) |
| 0.6 | 2.3 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
| 0.5 | 1.6 | GO:0042642 | actomyosin, myosin complex part(GO:0042642) |
| 0.5 | 4.7 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.4 | 0.9 | GO:0008091 | spectrin(GO:0008091) |
| 0.4 | 3.2 | GO:0033269 | internode region of axon(GO:0033269) |
| 0.4 | 1.1 | GO:0071914 | prominosome(GO:0071914) |
| 0.4 | 1.9 | GO:0032133 | chromosome passenger complex(GO:0032133) |
| 0.4 | 1.1 | GO:0031088 | platelet dense granule membrane(GO:0031088) intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637) |
| 0.4 | 1.5 | GO:0089717 | spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717) |
| 0.3 | 8.4 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.3 | 2.1 | GO:0097513 | myosin II filament(GO:0097513) |
| 0.3 | 5.0 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.3 | 1.3 | GO:1990032 | parallel fiber(GO:1990032) |
| 0.3 | 3.2 | GO:0070545 | PeBoW complex(GO:0070545) |
| 0.3 | 1.3 | GO:0017071 | intracellular cyclic nucleotide activated cation channel complex(GO:0017071) |
| 0.3 | 2.4 | GO:0033648 | host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648) |
| 0.3 | 1.1 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
| 0.3 | 1.0 | GO:0000235 | astral microtubule(GO:0000235) |
| 0.2 | 8.5 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.2 | 1.0 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 0.2 | 0.5 | GO:1990812 | growth cone filopodium(GO:1990812) |
| 0.2 | 2.9 | GO:0016600 | flotillin complex(GO:0016600) |
| 0.2 | 1.2 | GO:0031523 | Myb complex(GO:0031523) |
| 0.2 | 3.2 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.2 | 1.3 | GO:0005726 | perichromatin fibrils(GO:0005726) |
| 0.2 | 0.9 | GO:1902937 | inward rectifier potassium channel complex(GO:1902937) |
| 0.2 | 5.3 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.2 | 9.1 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.2 | 1.0 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.2 | 7.3 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
| 0.2 | 2.9 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.2 | 1.9 | GO:0030130 | clathrin coat of trans-Golgi network vesicle(GO:0030130) |
| 0.2 | 0.9 | GO:0005861 | troponin complex(GO:0005861) |
| 0.2 | 6.6 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.2 | 0.8 | GO:0072487 | MSL complex(GO:0072487) |
| 0.2 | 1.0 | GO:0044308 | axonal spine(GO:0044308) |
| 0.2 | 2.5 | GO:0030673 | axolemma(GO:0030673) |
| 0.2 | 0.8 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
| 0.2 | 1.7 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.2 | 2.8 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
| 0.2 | 3.3 | GO:0035253 | ciliary rootlet(GO:0035253) |
| 0.2 | 1.1 | GO:0033503 | HULC complex(GO:0033503) |
| 0.2 | 1.3 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
| 0.2 | 0.7 | GO:0031673 | H zone(GO:0031673) |
| 0.2 | 0.8 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.2 | 0.9 | GO:0030896 | checkpoint clamp complex(GO:0030896) |
| 0.1 | 0.7 | GO:0070852 | cell body fiber(GO:0070852) |
| 0.1 | 1.7 | GO:0061700 | GATOR2 complex(GO:0061700) |
| 0.1 | 5.7 | GO:0002102 | podosome(GO:0002102) |
| 0.1 | 0.9 | GO:0010369 | chromocenter(GO:0010369) |
| 0.1 | 0.5 | GO:0030132 | clathrin coat of coated pit(GO:0030132) |
| 0.1 | 1.8 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
| 0.1 | 0.3 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
| 0.1 | 1.2 | GO:0005642 | annulate lamellae(GO:0005642) |
| 0.1 | 0.2 | GO:0000836 | ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836) |
| 0.1 | 0.6 | GO:0031314 | extrinsic component of mitochondrial inner membrane(GO:0031314) |
| 0.1 | 0.7 | GO:0071203 | WASH complex(GO:0071203) |
| 0.1 | 1.5 | GO:0000974 | Prp19 complex(GO:0000974) |
| 0.1 | 1.2 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.1 | 0.7 | GO:0070419 | nonhomologous end joining complex(GO:0070419) |
| 0.1 | 0.9 | GO:0048787 | presynaptic active zone membrane(GO:0048787) |
| 0.1 | 2.8 | GO:0031430 | M band(GO:0031430) |
| 0.1 | 1.5 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.1 | 1.5 | GO:0043196 | varicosity(GO:0043196) |
| 0.1 | 3.0 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 0.1 | 0.5 | GO:1990745 | EARP complex(GO:1990745) |
| 0.1 | 3.0 | GO:0005811 | lipid particle(GO:0005811) |
| 0.1 | 1.5 | GO:0005640 | nuclear outer membrane(GO:0005640) |
| 0.1 | 1.2 | GO:1990635 | proximal dendrite(GO:1990635) |
| 0.1 | 0.5 | GO:0070847 | core mediator complex(GO:0070847) |
| 0.1 | 3.1 | GO:0016592 | mediator complex(GO:0016592) |
| 0.1 | 0.6 | GO:0044326 | dendritic spine neck(GO:0044326) |
| 0.1 | 0.3 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
| 0.1 | 0.6 | GO:0070695 | FHF complex(GO:0070695) |
| 0.1 | 3.9 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.1 | 0.6 | GO:0042824 | MHC class I peptide loading complex(GO:0042824) |
| 0.1 | 0.8 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.1 | 1.5 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.1 | 0.7 | GO:0002177 | manchette(GO:0002177) |
| 0.1 | 0.2 | GO:0043224 | nuclear SCF ubiquitin ligase complex(GO:0043224) |
| 0.1 | 0.5 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 0.1 | 7.0 | GO:0030136 | clathrin-coated vesicle(GO:0030136) |
| 0.1 | 0.7 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
| 0.1 | 0.9 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.1 | 0.3 | GO:0035339 | SPOTS complex(GO:0035339) |
| 0.1 | 3.0 | GO:0005938 | cell cortex(GO:0005938) |
| 0.1 | 0.3 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
| 0.1 | 0.6 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
| 0.1 | 1.0 | GO:0036513 | Derlin-1 retrotranslocation complex(GO:0036513) |
| 0.1 | 0.4 | GO:0061689 | tricellular tight junction(GO:0061689) |
| 0.1 | 0.1 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.1 | 0.7 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 0.1 | 11.2 | GO:0032993 | protein-DNA complex(GO:0032993) |
| 0.1 | 2.2 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.1 | 0.2 | GO:1990130 | Seh1-associated complex(GO:0035859) Iml1 complex(GO:1990130) |
| 0.1 | 2.6 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.1 | 0.5 | GO:0097427 | microtubule bundle(GO:0097427) |
| 0.1 | 0.7 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.1 | 3.2 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
| 0.1 | 2.7 | GO:0016459 | myosin complex(GO:0016459) |
| 0.1 | 2.4 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.1 | 0.4 | GO:0071817 | MMXD complex(GO:0071817) |
| 0.1 | 0.9 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.1 | 0.1 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.1 | 2.6 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.1 | 0.7 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 0.1 | 0.6 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
| 0.1 | 0.5 | GO:0061574 | ASAP complex(GO:0061574) |
| 0.1 | 6.2 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.0 | 0.6 | GO:0031597 | cytosolic proteasome complex(GO:0031597) |
| 0.0 | 0.3 | GO:0005964 | phosphorylase kinase complex(GO:0005964) |
| 0.0 | 0.1 | GO:0097058 | CRLF-CLCF1 complex(GO:0097058) |
| 0.0 | 0.7 | GO:0097539 | ciliary transition fiber(GO:0097539) |
| 0.0 | 1.2 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.0 | 0.3 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
| 0.0 | 0.2 | GO:0030289 | protein phosphatase 4 complex(GO:0030289) |
| 0.0 | 0.1 | GO:0044352 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 0.0 | 1.0 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.0 | 0.7 | GO:0033276 | transcription factor TFTC complex(GO:0033276) |
| 0.0 | 3.7 | GO:0055037 | recycling endosome(GO:0055037) |
| 0.0 | 0.9 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.0 | 0.4 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 0.0 | 1.1 | GO:0015030 | Cajal body(GO:0015030) |
| 0.0 | 0.9 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.0 | 0.3 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.0 | 1.0 | GO:0030119 | AP-type membrane coat adaptor complex(GO:0030119) |
| 0.0 | 0.4 | GO:0030018 | Z disc(GO:0030018) |
| 0.0 | 4.7 | GO:0043679 | axon terminus(GO:0043679) |
| 0.0 | 0.3 | GO:0005851 | eukaryotic translation initiation factor 2B complex(GO:0005851) |
| 0.0 | 11.3 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.0 | 0.3 | GO:0005787 | signal peptidase complex(GO:0005787) |
| 0.0 | 0.2 | GO:0036157 | outer dynein arm(GO:0036157) |
| 0.0 | 1.4 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.0 | 0.1 | GO:0005594 | collagen type IX trimer(GO:0005594) |
| 0.0 | 1.2 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.0 | 0.4 | GO:0000242 | pericentriolar material(GO:0000242) |
| 0.0 | 0.3 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.0 | 0.4 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.0 | 0.2 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
| 0.0 | 0.7 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.0 | 5.5 | GO:0014069 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
| 0.0 | 0.4 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.0 | 0.2 | GO:0031105 | septin complex(GO:0031105) |
| 0.0 | 0.8 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.0 | 1.5 | GO:0000502 | proteasome complex(GO:0000502) |
| 0.0 | 0.6 | GO:0000795 | synaptonemal complex(GO:0000795) |
| 0.0 | 1.6 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 1.6 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.0 | 2.3 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 0.0 | 0.3 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.0 | 0.2 | GO:0034709 | methylosome(GO:0034709) |
| 0.0 | 1.9 | GO:0030496 | midbody(GO:0030496) |
| 0.0 | 1.7 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 0.3 | GO:0005865 | striated muscle thin filament(GO:0005865) myofilament(GO:0036379) |
| 0.0 | 0.4 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.0 | 0.2 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.0 | 0.3 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
| 0.0 | 0.7 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
| 0.0 | 0.1 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
| 0.0 | 0.2 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 0.0 | 2.6 | GO:0043235 | receptor complex(GO:0043235) |
| 0.0 | 0.1 | GO:0070552 | BRISC complex(GO:0070552) |
| 0.0 | 0.4 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.0 | 0.1 | GO:0042571 | immunoglobulin complex(GO:0019814) immunoglobulin complex, circulating(GO:0042571) |
| 0.0 | 0.0 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
| 0.0 | 0.2 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.6 | 18.2 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 2.0 | 5.9 | GO:0004489 | methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489) |
| 1.5 | 4.5 | GO:0000822 | inositol hexakisphosphate binding(GO:0000822) |
| 1.4 | 7.1 | GO:0043532 | angiostatin binding(GO:0043532) |
| 1.3 | 8.1 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
| 0.9 | 2.8 | GO:0016964 | alpha-2 macroglobulin receptor activity(GO:0016964) |
| 0.8 | 2.5 | GO:0036004 | GAF domain binding(GO:0036004) |
| 0.8 | 2.4 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
| 0.7 | 6.0 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 0.7 | 0.7 | GO:0016820 | hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820) |
| 0.6 | 1.9 | GO:0034190 | apolipoprotein receptor binding(GO:0034190) |
| 0.6 | 1.7 | GO:0046538 | bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538) |
| 0.6 | 1.7 | GO:0071936 | coreceptor activity involved in Wnt signaling pathway(GO:0071936) |
| 0.5 | 2.7 | GO:0072542 | protein phosphatase activator activity(GO:0072542) |
| 0.5 | 18.8 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.5 | 1.5 | GO:0034437 | glycoprotein transporter activity(GO:0034437) |
| 0.5 | 1.5 | GO:0042936 | dipeptide transporter activity(GO:0042936) |
| 0.5 | 2.4 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
| 0.5 | 8.3 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.5 | 4.8 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.5 | 2.3 | GO:0086080 | protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
| 0.4 | 1.8 | GO:0008142 | oxysterol binding(GO:0008142) |
| 0.4 | 1.3 | GO:0035575 | histone demethylase activity (H4-K20 specific)(GO:0035575) |
| 0.4 | 0.9 | GO:0050780 | dopamine receptor binding(GO:0050780) |
| 0.4 | 1.7 | GO:0005093 | Rab GDP-dissociation inhibitor activity(GO:0005093) |
| 0.4 | 1.7 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
| 0.4 | 2.4 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
| 0.4 | 1.6 | GO:0017077 | oxidative phosphorylation uncoupler activity(GO:0017077) |
| 0.4 | 0.4 | GO:0000992 | polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) |
| 0.4 | 1.1 | GO:0004774 | succinate-CoA ligase activity(GO:0004774) |
| 0.4 | 1.1 | GO:0003987 | acetate-CoA ligase activity(GO:0003987) |
| 0.4 | 1.8 | GO:0035240 | dopamine binding(GO:0035240) |
| 0.3 | 2.4 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
| 0.3 | 5.2 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.3 | 1.0 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
| 0.3 | 0.9 | GO:0001225 | RNA polymerase II transcription coactivator binding(GO:0001225) |
| 0.3 | 2.5 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
| 0.3 | 2.1 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
| 0.3 | 5.6 | GO:0001848 | complement binding(GO:0001848) |
| 0.3 | 4.9 | GO:0001134 | transcription factor activity, transcription factor recruiting(GO:0001134) |
| 0.3 | 0.8 | GO:0047192 | 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192) |
| 0.3 | 2.7 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
| 0.3 | 5.6 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.3 | 3.5 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.3 | 1.3 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
| 0.2 | 0.7 | GO:0004993 | G-protein coupled serotonin receptor activity(GO:0004993) serotonin binding(GO:0051378) |
| 0.2 | 0.7 | GO:0016015 | morphogen activity(GO:0016015) |
| 0.2 | 1.0 | GO:0004921 | interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970) |
| 0.2 | 0.7 | GO:0042954 | lipoprotein transporter activity(GO:0042954) |
| 0.2 | 3.2 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
| 0.2 | 0.7 | GO:0019966 | interleukin-1 binding(GO:0019966) |
| 0.2 | 0.7 | GO:0031752 | D5 dopamine receptor binding(GO:0031752) |
| 0.2 | 0.9 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
| 0.2 | 4.0 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
| 0.2 | 1.8 | GO:0046934 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813) |
| 0.2 | 2.2 | GO:0004445 | inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030) |
| 0.2 | 0.6 | GO:0004743 | pyruvate kinase activity(GO:0004743) |
| 0.2 | 5.6 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.2 | 2.5 | GO:0070742 | C2H2 zinc finger domain binding(GO:0070742) |
| 0.2 | 1.9 | GO:0043995 | histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972) |
| 0.2 | 1.0 | GO:0035174 | histone serine kinase activity(GO:0035174) |
| 0.2 | 0.6 | GO:0030519 | snoRNP binding(GO:0030519) |
| 0.2 | 3.3 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.2 | 1.0 | GO:1904288 | BAT3 complex binding(GO:1904288) |
| 0.2 | 0.8 | GO:0016833 | oxo-acid-lyase activity(GO:0016833) |
| 0.2 | 4.1 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
| 0.2 | 7.9 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.2 | 0.6 | GO:0036132 | 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522) |
| 0.2 | 0.6 | GO:0070890 | L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890) |
| 0.2 | 0.6 | GO:0003996 | acyl-CoA ligase activity(GO:0003996) CoA-ligase activity(GO:0016405) |
| 0.2 | 3.7 | GO:0000146 | microfilament motor activity(GO:0000146) |
| 0.2 | 5.4 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.2 | 1.1 | GO:0044547 | DNA topoisomerase binding(GO:0044547) |
| 0.2 | 0.4 | GO:0071987 | WD40-repeat domain binding(GO:0071987) |
| 0.2 | 0.9 | GO:0031014 | troponin T binding(GO:0031014) |
| 0.2 | 0.9 | GO:1904047 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) S-adenosyl-L-methionine binding(GO:1904047) |
| 0.2 | 3.4 | GO:0098632 | protein binding involved in cell-cell adhesion(GO:0098632) |
| 0.2 | 3.6 | GO:0031402 | sodium ion binding(GO:0031402) |
| 0.2 | 0.9 | GO:0004359 | glutaminase activity(GO:0004359) |
| 0.2 | 1.7 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
| 0.2 | 0.5 | GO:0008527 | taste receptor activity(GO:0008527) |
| 0.2 | 1.0 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.2 | 1.2 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.2 | 2.8 | GO:0030247 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
| 0.2 | 2.1 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.2 | 0.9 | GO:0034452 | dynactin binding(GO:0034452) |
| 0.2 | 5.7 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.2 | 1.8 | GO:0070008 | serine-type exopeptidase activity(GO:0070008) |
| 0.2 | 0.5 | GO:0016748 | succinyltransferase activity(GO:0016748) |
| 0.2 | 4.9 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.1 | 1.5 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
| 0.1 | 4.2 | GO:0051183 | vitamin transporter activity(GO:0051183) |
| 0.1 | 1.1 | GO:0005131 | growth hormone receptor binding(GO:0005131) |
| 0.1 | 1.8 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.1 | 0.7 | GO:0003945 | N-acetyllactosamine synthase activity(GO:0003945) |
| 0.1 | 1.4 | GO:0003964 | telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964) |
| 0.1 | 0.4 | GO:0016716 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716) |
| 0.1 | 0.5 | GO:0001733 | galactosylceramide sulfotransferase activity(GO:0001733) |
| 0.1 | 1.2 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
| 0.1 | 0.4 | GO:0004769 | steroid delta-isomerase activity(GO:0004769) |
| 0.1 | 0.8 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
| 0.1 | 0.4 | GO:0030249 | guanylate cyclase regulator activity(GO:0030249) |
| 0.1 | 2.3 | GO:0047555 | 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555) |
| 0.1 | 1.0 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
| 0.1 | 1.0 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 0.1 | 1.0 | GO:0016670 | oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670) |
| 0.1 | 1.3 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.1 | 0.7 | GO:0097001 | ceramide binding(GO:0097001) |
| 0.1 | 0.3 | GO:0043176 | amine binding(GO:0043176) |
| 0.1 | 1.3 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
| 0.1 | 2.7 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.1 | 0.5 | GO:0045545 | syndecan binding(GO:0045545) |
| 0.1 | 1.3 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.1 | 2.7 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.1 | 1.9 | GO:0008432 | JUN kinase binding(GO:0008432) |
| 0.1 | 1.3 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
| 0.1 | 1.3 | GO:0043495 | protein anchor(GO:0043495) |
| 0.1 | 5.9 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.1 | 1.4 | GO:0031005 | filamin binding(GO:0031005) |
| 0.1 | 0.3 | GO:0061628 | H3K27me3 modified histone binding(GO:0061628) |
| 0.1 | 0.6 | GO:0003910 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
| 0.1 | 2.0 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.1 | 0.5 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.1 | 0.6 | GO:0016532 | superoxide dismutase copper chaperone activity(GO:0016532) |
| 0.1 | 3.3 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.1 | 1.1 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.1 | 0.7 | GO:0051400 | BH domain binding(GO:0051400) |
| 0.1 | 1.1 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.1 | 0.5 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.1 | 0.3 | GO:0004758 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
| 0.1 | 0.4 | GO:0048408 | epidermal growth factor binding(GO:0048408) |
| 0.1 | 15.6 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.1 | 0.6 | GO:1901612 | phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612) |
| 0.1 | 0.7 | GO:1990380 | Lys48-specific deubiquitinase activity(GO:1990380) |
| 0.1 | 0.3 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
| 0.1 | 1.1 | GO:0070513 | death domain binding(GO:0070513) |
| 0.1 | 0.6 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
| 0.1 | 3.7 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.1 | 0.7 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.1 | 2.1 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.1 | 0.7 | GO:0017151 | DEAD/H-box RNA helicase binding(GO:0017151) |
| 0.1 | 0.7 | GO:0015250 | water channel activity(GO:0015250) |
| 0.1 | 3.5 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.1 | 0.3 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
| 0.1 | 0.3 | GO:0004852 | uroporphyrinogen-III synthase activity(GO:0004852) |
| 0.1 | 0.7 | GO:0035312 | 5'-3' exodeoxyribonuclease activity(GO:0035312) |
| 0.1 | 1.2 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
| 0.1 | 2.8 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.1 | 0.3 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
| 0.1 | 0.4 | GO:0030375 | thyroid hormone receptor coactivator activity(GO:0030375) |
| 0.1 | 0.3 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.1 | 2.6 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.1 | 0.3 | GO:0051377 | mannose-ethanolamine phosphotransferase activity(GO:0051377) |
| 0.1 | 1.0 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.1 | 1.1 | GO:0031748 | D1 dopamine receptor binding(GO:0031748) |
| 0.1 | 0.7 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.1 | 4.1 | GO:0005518 | collagen binding(GO:0005518) |
| 0.1 | 18.3 | GO:0000987 | core promoter proximal region sequence-specific DNA binding(GO:0000987) |
| 0.1 | 0.2 | GO:0017099 | very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099) |
| 0.1 | 1.0 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
| 0.1 | 2.7 | GO:0001158 | enhancer sequence-specific DNA binding(GO:0001158) |
| 0.1 | 0.3 | GO:0004703 | G-protein coupled receptor kinase activity(GO:0004703) |
| 0.1 | 1.2 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.1 | 0.6 | GO:0035251 | UDP-glucosyltransferase activity(GO:0035251) |
| 0.1 | 1.3 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.1 | 1.3 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.1 | 1.5 | GO:0018024 | histone-lysine N-methyltransferase activity(GO:0018024) |
| 0.1 | 0.8 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 0.1 | 10.7 | GO:0001047 | core promoter binding(GO:0001047) |
| 0.1 | 2.3 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
| 0.1 | 0.3 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.1 | 0.8 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 0.1 | 1.0 | GO:0070840 | dynein complex binding(GO:0070840) |
| 0.1 | 0.9 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.1 | 0.2 | GO:0046624 | sphingolipid transporter activity(GO:0046624) |
| 0.1 | 0.3 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 0.1 | 0.3 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.1 | 0.6 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.1 | 1.1 | GO:0043274 | phospholipase binding(GO:0043274) |
| 0.1 | 0.2 | GO:0004844 | uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506) |
| 0.0 | 0.2 | GO:0031800 | type 3 metabotropic glutamate receptor binding(GO:0031800) |
| 0.0 | 0.4 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
| 0.0 | 0.2 | GO:0004322 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.0 | 0.3 | GO:0004689 | phosphorylase kinase activity(GO:0004689) |
| 0.0 | 0.3 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 0.0 | 1.9 | GO:0030170 | pyridoxal phosphate binding(GO:0030170) |
| 0.0 | 0.1 | GO:0004348 | glucosylceramidase activity(GO:0004348) |
| 0.0 | 0.7 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.0 | 0.9 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 0.0 | 1.4 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.0 | 0.1 | GO:0035662 | Toll-like receptor 4 binding(GO:0035662) |
| 0.0 | 2.3 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
| 0.0 | 0.8 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
| 0.0 | 1.0 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.0 | 0.3 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.0 | 0.7 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.0 | 0.3 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
| 0.0 | 0.4 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
| 0.0 | 0.4 | GO:0015217 | ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217) |
| 0.0 | 1.5 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.0 | 0.8 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 0.5 | GO:0070063 | RNA polymerase binding(GO:0070063) |
| 0.0 | 0.2 | GO:0016278 | lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279) |
| 0.0 | 0.4 | GO:0070888 | E-box binding(GO:0070888) |
| 0.0 | 1.6 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.0 | 0.2 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.0 | 0.2 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
| 0.0 | 1.2 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
| 0.0 | 0.2 | GO:0004165 | dodecenoyl-CoA delta-isomerase activity(GO:0004165) |
| 0.0 | 0.4 | GO:1990381 | ubiquitin-specific protease binding(GO:1990381) |
| 0.0 | 7.1 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
| 0.0 | 0.2 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.0 | 0.3 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.0 | 0.8 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
| 0.0 | 0.3 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.0 | 0.1 | GO:0005127 | ciliary neurotrophic factor receptor binding(GO:0005127) |
| 0.0 | 0.2 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
| 0.0 | 0.4 | GO:0004559 | alpha-mannosidase activity(GO:0004559) |
| 0.0 | 0.3 | GO:0004622 | lysophospholipase activity(GO:0004622) |
| 0.0 | 0.5 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.0 | 0.1 | GO:0003872 | 6-phosphofructokinase activity(GO:0003872) |
| 0.0 | 0.6 | GO:0031369 | translation initiation factor binding(GO:0031369) |
| 0.0 | 1.2 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.0 | 0.5 | GO:0030331 | estrogen receptor binding(GO:0030331) |
| 0.0 | 0.2 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
| 0.0 | 1.2 | GO:0005088 | Ras guanyl-nucleotide exchange factor activity(GO:0005088) |
| 0.0 | 0.4 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.0 | 0.0 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
| 0.0 | 1.4 | GO:0008080 | N-acetyltransferase activity(GO:0008080) |
| 0.0 | 1.7 | GO:0036459 | thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005) |
| 0.0 | 0.5 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.0 | 0.6 | GO:0042562 | hormone binding(GO:0042562) |
| 0.0 | 0.1 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
| 0.0 | 0.5 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.0 | 0.5 | GO:0051219 | phosphoprotein binding(GO:0051219) |
| 0.0 | 0.2 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
| 0.0 | 0.7 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.0 | 9.3 | GO:0019904 | protein domain specific binding(GO:0019904) |
| 0.0 | 1.5 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.0 | 0.1 | GO:0004719 | protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719) |
| 0.0 | 0.7 | GO:0005254 | chloride channel activity(GO:0005254) |
| 0.0 | 0.2 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
| 0.0 | 0.2 | GO:0019103 | pyrimidine nucleotide binding(GO:0019103) |
| 0.0 | 1.0 | GO:0003713 | transcription coactivator activity(GO:0003713) |
| 0.0 | 0.2 | GO:0051721 | protein phosphatase 2A binding(GO:0051721) |
| 0.0 | 0.1 | GO:0070567 | cytidylyltransferase activity(GO:0070567) |
| 0.0 | 0.5 | GO:0032934 | sterol binding(GO:0032934) |
| 0.0 | 0.2 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.0 | 0.2 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 3.2 | PID_PDGFRA_PATHWAY | PDGFR-alpha signaling pathway |
| 0.6 | 20.5 | PID_HEDGEHOG_2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.3 | 1.0 | ST_IL_13_PATHWAY | Interleukin 13 (IL-13) Pathway |
| 0.2 | 9.4 | PID_AURORA_B_PATHWAY | Aurora B signaling |
| 0.2 | 3.8 | PID_EPHA2_FWD_PATHWAY | EPHA2 forward signaling |
| 0.2 | 5.4 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
| 0.2 | 6.7 | SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.1 | 3.1 | PID_P38_MK2_PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.1 | 4.9 | ST_GRANULE_CELL_SURVIVAL_PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
| 0.1 | 3.2 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
| 0.1 | 7.8 | PID_RAC1_REG_PATHWAY | Regulation of RAC1 activity |
| 0.1 | 5.3 | PID_THROMBIN_PAR1_PATHWAY | PAR1-mediated thrombin signaling events |
| 0.1 | 2.6 | PID_ECADHERIN_KERATINOCYTE_PATHWAY | E-cadherin signaling in keratinocytes |
| 0.1 | 0.7 | PID_TCR_RAS_PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.1 | 0.4 | SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
| 0.1 | 3.1 | PID_EPHB_FWD_PATHWAY | EPHB forward signaling |
| 0.1 | 5.2 | SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES | Genes related to the insulin receptor pathway |
| 0.1 | 2.6 | ST_WNT_BETA_CATENIN_PATHWAY | Wnt/beta-catenin Pathway |
| 0.1 | 1.3 | PID_ERB_GENOMIC_PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.1 | 3.1 | PID_HIV_NEF_PATHWAY | HIV-1 Nef: Negative effector of Fas and TNF-alpha |
| 0.1 | 3.4 | PID_ERBB4_PATHWAY | ErbB4 signaling events |
| 0.1 | 0.8 | PID_ALK2_PATHWAY | ALK2 signaling events |
| 0.1 | 0.6 | ST_GA12_PATHWAY | G alpha 12 Pathway |
| 0.1 | 2.6 | PID_CASPASE_PATHWAY | Caspase cascade in apoptosis |
| 0.1 | 1.8 | PID_RAS_PATHWAY | Regulation of Ras family activation |
| 0.1 | 2.5 | PID_RHOA_PATHWAY | RhoA signaling pathway |
| 0.1 | 0.7 | PID_SYNDECAN_2_PATHWAY | Syndecan-2-mediated signaling events |
| 0.1 | 0.3 | PID_IL5_PATHWAY | IL5-mediated signaling events |
| 0.1 | 2.9 | PID_AR_TF_PATHWAY | Regulation of Androgen receptor activity |
| 0.1 | 0.9 | PID_HDAC_CLASSIII_PATHWAY | Signaling events mediated by HDAC Class III |
| 0.1 | 1.1 | PID_NCADHERIN_PATHWAY | N-cadherin signaling events |
| 0.1 | 3.3 | PID_ERA_GENOMIC_PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 1.0 | PID_P38_MKK3_6PATHWAY | p38 MAPK signaling pathway |
| 0.0 | 3.8 | PID_E2F_PATHWAY | E2F transcription factor network |
| 0.0 | 0.5 | PID_SYNDECAN_3_PATHWAY | Syndecan-3-mediated signaling events |
| 0.0 | 1.5 | PID_HNF3B_PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 0.4 | PID_RHODOPSIN_PATHWAY | Visual signal transduction: Rods |
| 0.0 | 0.2 | PID_ARF6_DOWNSTREAM_PATHWAY | Arf6 downstream pathway |
| 0.0 | 1.1 | PID_ATM_PATHWAY | ATM pathway |
| 0.0 | 1.2 | PID_DELTA_NP63_PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.0 | 2.5 | PID_AR_PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 0.2 | PID_CERAMIDE_PATHWAY | Ceramide signaling pathway |
| 0.0 | 1.1 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 0.4 | PID_IL1_PATHWAY | IL1-mediated signaling events |
| 0.0 | 0.2 | PID_HIF1A_PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.0 | 0.3 | ST_GA13_PATHWAY | G alpha 13 Pathway |
| 0.0 | 1.0 | PID_HES_HEY_PATHWAY | Notch-mediated HES/HEY network |
| 0.0 | 0.5 | PID_CIRCADIAN_PATHWAY | Circadian rhythm pathway |
| 0.0 | 0.3 | ST_ADRENERGIC | Adrenergic Pathway |
| 0.0 | 0.7 | PID_BCR_5PATHWAY | BCR signaling pathway |
| 0.0 | 0.7 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 0.6 | PID_FANCONI_PATHWAY | Fanconi anemia pathway |
| 0.0 | 0.4 | PID_ERBB1_INTERNALIZATION_PATHWAY | Internalization of ErbB1 |
| 0.0 | 0.7 | PID_PLK1_PATHWAY | PLK1 signaling events |
| 0.0 | 0.7 | PID_LKB1_PATHWAY | LKB1 signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 6.0 | REACTOME_INTRINSIC_PATHWAY | Genes involved in Intrinsic Pathway |
| 0.4 | 9.6 | REACTOME_KINESINS | Genes involved in Kinesins |
| 0.3 | 3.9 | REACTOME_IL_6_SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.3 | 9.3 | REACTOME_SIGNALING_BY_HIPPO | Genes involved in Signaling by Hippo |
| 0.3 | 1.1 | REACTOME_ETHANOL_OXIDATION | Genes involved in Ethanol oxidation |
| 0.3 | 1.0 | REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 | Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 |
| 0.2 | 0.7 | REACTOME_SEROTONIN_RECEPTORS | Genes involved in Serotonin receptors |
| 0.2 | 1.5 | REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
| 0.2 | 5.5 | REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.2 | 7.1 | REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS | Genes involved in Fatty Acyl-CoA Biosynthesis |
| 0.2 | 4.7 | REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
| 0.2 | 1.1 | REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.2 | 1.8 | REACTOME_AMINE_DERIVED_HORMONES | Genes involved in Amine-derived hormones |
| 0.2 | 4.8 | REACTOME_NEPHRIN_INTERACTIONS | Genes involved in Nephrin interactions |
| 0.1 | 3.5 | REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.1 | 2.4 | REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY | Genes involved in Notch-HLH transcription pathway |
| 0.1 | 5.0 | REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING | Genes involved in Sema4D in semaphorin signaling |
| 0.1 | 4.0 | REACTOME_THE_ROLE_OF_NEF_IN_HIV1_REPLICATION_AND_DISEASE_PATHOGENESIS | Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis |
| 0.1 | 1.2 | REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.1 | 2.5 | REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.1 | 1.0 | REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR | Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR) |
| 0.1 | 1.1 | REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX | Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex |
| 0.1 | 2.7 | REACTOME_CGMP_EFFECTS | Genes involved in cGMP effects |
| 0.1 | 1.5 | REACTOME_HYALURONAN_METABOLISM | Genes involved in Hyaluronan metabolism |
| 0.1 | 0.7 | REACTOME_SIGNALING_BY_NODAL | Genes involved in Signaling by NODAL |
| 0.1 | 5.4 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.1 | 6.4 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | Genes involved in NRAGE signals death through JNK |
| 0.1 | 1.5 | REACTOME_P38MAPK_EVENTS | Genes involved in p38MAPK events |
| 0.1 | 0.7 | REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.1 | 2.8 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.1 | 0.9 | REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 0.1 | 1.8 | REACTOME_G0_AND_EARLY_G1 | Genes involved in G0 and Early G1 |
| 0.1 | 1.5 | REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.1 | 0.7 | REACTOME_SIGNALING_BY_FGFR3_MUTANTS | Genes involved in Signaling by FGFR3 mutants |
| 0.1 | 6.2 | REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.1 | 1.6 | REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.1 | 0.6 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.1 | 0.7 | REACTOME_G_ALPHA1213_SIGNALLING_EVENTS | Genes involved in G alpha (12/13) signalling events |
| 0.1 | 0.6 | REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
| 0.1 | 0.7 | REACTOME_CS_DS_DEGRADATION | Genes involved in CS/DS degradation |
| 0.1 | 4.6 | REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.1 | 1.1 | REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS | Genes involved in Viral Messenger RNA Synthesis |
| 0.1 | 0.9 | REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 0.1 | 1.6 | REACTOME_OTHER_SEMAPHORIN_INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.1 | 0.3 | REACTOME_RAF_MAP_KINASE_CASCADE | Genes involved in RAF/MAP kinase cascade |
| 0.1 | 0.7 | REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY | Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway |
| 0.1 | 0.8 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PC | Genes involved in Acyl chain remodelling of PC |
| 0.1 | 1.8 | REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.1 | 0.8 | REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.1 | 1.1 | REACTOME_METABOLISM_OF_PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.1 | 1.1 | REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.0 | 0.4 | REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.0 | 1.3 | REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.0 | 1.0 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_PLASMA_MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.0 | 1.3 | REACTOME_PIP3_ACTIVATES_AKT_SIGNALING | Genes involved in PIP3 activates AKT signaling |
| 0.0 | 0.5 | REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR | Genes involved in Regulated proteolysis of p75NTR |
| 0.0 | 0.4 | REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS | Genes involved in Interactions of Vpr with host cellular proteins |
| 0.0 | 0.9 | REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter |
| 0.0 | 1.6 | REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 0.0 | 0.9 | REACTOME_STRIATED_MUSCLE_CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.0 | 0.7 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.0 | 1.4 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.0 | 0.4 | REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 0.0 | 0.5 | REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.0 | 0.3 | REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
| 0.0 | 0.7 | REACTOME_INSULIN_RECEPTOR_RECYCLING | Genes involved in Insulin receptor recycling |
| 0.0 | 0.6 | REACTOME_SYNTHESIS_OF_PC | Genes involved in Synthesis of PC |
| 0.0 | 0.3 | REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |
| 0.0 | 0.6 | REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 | Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
| 0.0 | 2.1 | REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 0.0 | 0.8 | REACTOME_TRIGLYCERIDE_BIOSYNTHESIS | Genes involved in Triglyceride Biosynthesis |
| 0.0 | 0.6 | REACTOME_FANCONI_ANEMIA_PATHWAY | Genes involved in Fanconi Anemia pathway |
| 0.0 | 0.3 | REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.0 | 6.3 | REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.0 | 0.3 | REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.0 | 0.4 | REACTOME_IL1_SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.0 | 0.3 | REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
| 0.0 | 0.8 | REACTOME_MRNA_SPLICING_MINOR_PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
| 0.0 | 0.2 | REACTOME_IRON_UPTAKE_AND_TRANSPORT | Genes involved in Iron uptake and transport |
| 0.0 | 0.4 | REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.0 | 0.2 | REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS | Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements |
| 0.0 | 1.7 | REACTOME_SIGNALING_BY_RHO_GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.0 | 0.2 | REACTOME_PURINE_CATABOLISM | Genes involved in Purine catabolism |
| 0.0 | 0.9 | REACTOME_MEIOTIC_SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.0 | 0.4 | REACTOME_CHOLESTEROL_BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.0 | 0.7 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.0 | 0.2 | REACTOME_PURINE_SALVAGE | Genes involved in Purine salvage |
| 0.0 | 0.1 | REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.0 | 0.1 | REACTOME_ACTIVATION_OF_RAC | Genes involved in Activation of Rac |
| 0.0 | 0.2 | REACTOME_EGFR_DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.0 | 0.3 | REACTOME_MEIOTIC_RECOMBINATION | Genes involved in Meiotic Recombination |
