Motif ID: Gbx1_Nobox_Alx3

Z-value: 0.564

Transcription factors associated with Gbx1_Nobox_Alx3:

Gene SymbolEntrez IDGene Name
Alx3 ENSMUSG00000014603.1 Alx3
Gbx1 ENSMUSG00000067724.4 Gbx1
Nobox ENSMUSG00000029736.9 Nobox

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Alx3mm10_v2_chr3_+_107595031_1075951640.114.1e-01Click!
Gbx1mm10_v2_chr5_-_24527276_24527276-0.038.1e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Gbx1_Nobox_Alx3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_+_23415400 4.815 ENSMUST00000115832.2
ENSMUST00000047954.7
Dtna

dystrobrevin alpha

chr12_+_109545390 4.309 ENSMUST00000146701.1
Meg3
maternally expressed 3
chrX_-_143933089 4.156 ENSMUST00000087313.3
Dcx
doublecortin
chr15_-_11037968 3.709 ENSMUST00000058007.5
Rxfp3
relaxin family peptide receptor 3
chr11_-_98053415 3.650 ENSMUST00000017544.2
Stac2
SH3 and cysteine rich domain 2
chr2_+_125136692 3.563 ENSMUST00000099452.2
Ctxn2
cortexin 2
chr1_-_158356258 3.512 ENSMUST00000004133.8
Brinp2
bone morphogenic protein/retinoic acid inducible neural-specific 2
chr9_+_32116040 3.428 ENSMUST00000174641.1
Arhgap32
Rho GTPase activating protein 32
chr7_+_126950518 3.296 ENSMUST00000106335.1
ENSMUST00000146017.1
Sez6l2

seizure related 6 homolog like 2

chr3_+_55461758 3.027 ENSMUST00000070418.4
Dclk1
doublecortin-like kinase 1
chr15_+_92597104 3.007 ENSMUST00000035399.8
Pdzrn4
PDZ domain containing RING finger 4
chr4_+_108719649 2.882 ENSMUST00000178992.1
3110021N24Rik
RIKEN cDNA 3110021N24 gene
chr7_+_126950687 2.869 ENSMUST00000106333.1
Sez6l2
seizure related 6 homolog like 2
chr10_+_39612934 2.838 ENSMUST00000019987.6
Traf3ip2
TRAF3 interacting protein 2
chr16_-_42340595 2.815 ENSMUST00000102817.4
Gap43
growth associated protein 43
chr12_-_91849081 2.760 ENSMUST00000167466.1
ENSMUST00000021347.5
ENSMUST00000178462.1
Sel1l


sel-1 suppressor of lin-12-like (C. elegans)


chr1_+_72284367 2.733 ENSMUST00000027380.5
ENSMUST00000141783.1
Tmem169

transmembrane protein 169

chr9_-_55919605 2.715 ENSMUST00000037408.8
Scaper
S phase cyclin A-associated protein in the ER
chr1_-_155417394 2.589 ENSMUST00000111775.1
ENSMUST00000111774.1
Xpr1

xenotropic and polytropic retrovirus receptor 1

chr6_+_125552948 2.585 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Vwf


Von Willebrand factor homolog


chr15_+_21111452 2.525 ENSMUST00000075132.6
Cdh12
cadherin 12
chr13_+_42680565 2.491 ENSMUST00000128646.1
Phactr1
phosphatase and actin regulator 1
chr18_+_23752333 2.438 ENSMUST00000170802.1
ENSMUST00000155708.1
ENSMUST00000118826.2
Mapre2


microtubule-associated protein, RP/EB family, member 2


chr8_-_36249292 2.419 ENSMUST00000065297.5
Lonrf1
LON peptidase N-terminal domain and ring finger 1
chr19_+_26749726 2.331 ENSMUST00000175842.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr15_+_18818895 2.317 ENSMUST00000166873.2
Cdh10
cadherin 10
chr12_+_38780817 2.302 ENSMUST00000160856.1
Etv1
ets variant gene 1
chr12_+_52699297 2.266 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chr5_-_66514815 2.262 ENSMUST00000161879.1
ENSMUST00000159357.1
Apbb2

amyloid beta (A4) precursor protein-binding, family B, member 2

chr12_-_83487708 2.223 ENSMUST00000177959.1
ENSMUST00000178756.1
Dpf3

D4, zinc and double PHD fingers, family 3

chrX_-_143933204 2.203 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chr18_+_37518341 2.185 ENSMUST00000097609.1
Pcdhb22
protocadherin beta 22
chr6_-_136171722 2.184 ENSMUST00000053880.6
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr5_-_137684665 2.048 ENSMUST00000100544.4
ENSMUST00000031736.9
ENSMUST00000151839.1
Agfg2


ArfGAP with FG repeats 2


chr10_+_127421208 2.026 ENSMUST00000168780.1
R3hdm2
R3H domain containing 2
chr9_+_113812547 2.024 ENSMUST00000166734.2
ENSMUST00000111838.2
ENSMUST00000163895.2
Clasp2


CLIP associating protein 2


chr13_+_94083490 1.996 ENSMUST00000156071.1
Lhfpl2
lipoma HMGIC fusion partner-like 2
chr3_+_55782500 1.923 ENSMUST00000075422.4
Mab21l1
mab-21-like 1 (C. elegans)
chr8_+_23669653 1.838 ENSMUST00000042352.4
Zmat4
zinc finger, matrin type 4
chr1_-_134955847 1.836 ENSMUST00000168381.1
Ppp1r12b
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr16_-_37384915 1.830 ENSMUST00000114787.1
ENSMUST00000114782.1
ENSMUST00000023526.2
ENSMUST00000114775.1
Stxbp5l



syntaxin binding protein 5-like



chr2_+_109917639 1.816 ENSMUST00000046548.7
ENSMUST00000111037.2
Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chr6_+_29853746 1.802 ENSMUST00000064872.6
ENSMUST00000152581.1
ENSMUST00000176265.1
ENSMUST00000154079.1
Ahcyl2



S-adenosylhomocysteine hydrolase-like 2



chr12_+_38780284 1.798 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
Etv1


ets variant gene 1


chr10_+_85386813 1.778 ENSMUST00000105307.1
ENSMUST00000020231.3
Btbd11

BTB (POZ) domain containing 11

chr16_-_74411292 1.775 ENSMUST00000117200.1
Robo2
roundabout homolog 2 (Drosophila)
chr11_+_103133333 1.703 ENSMUST00000124928.1
ENSMUST00000062530.4
Hexim2

hexamethylene bis-acetamide inducible 2

chr18_-_75697639 1.671 ENSMUST00000165559.1
Ctif
CBP80/20-dependent translation initiation factor
chr8_+_121116163 1.562 ENSMUST00000054691.6
Foxc2
forkhead box C2
chr2_-_45112890 1.554 ENSMUST00000076836.6
Zeb2
zinc finger E-box binding homeobox 2
chr13_+_118714678 1.517 ENSMUST00000022246.8
Fgf10
fibroblast growth factor 10
chr1_-_134955908 1.473 ENSMUST00000045665.6
ENSMUST00000086444.4
ENSMUST00000112163.1
Ppp1r12b


protein phosphatase 1, regulatory (inhibitor) subunit 12B


chr11_+_103133303 1.426 ENSMUST00000107037.1
Hexim2
hexamethylene bis-acetamide inducible 2
chr3_+_68572245 1.419 ENSMUST00000170788.2
Schip1
schwannomin interacting protein 1
chr2_-_144527341 1.407 ENSMUST00000163701.1
ENSMUST00000081982.5
Dzank1

double zinc ribbon and ankyrin repeat domains 1

chr7_-_45103747 1.404 ENSMUST00000003512.7
Fcgrt
Fc receptor, IgG, alpha chain transporter
chr6_+_145934113 1.394 ENSMUST00000032383.7
Sspn
sarcospan
chr10_-_25200110 1.380 ENSMUST00000100012.2
Akap7
A kinase (PRKA) anchor protein 7
chr16_-_76373827 1.374 ENSMUST00000121927.1
Nrip1
nuclear receptor interacting protein 1
chr12_+_72441852 1.362 ENSMUST00000162159.1
Lrrc9
leucine rich repeat containing 9
chr5_+_81021202 1.352 ENSMUST00000117253.1
ENSMUST00000120128.1
Lphn3

latrophilin 3

chr19_+_26750939 1.346 ENSMUST00000175953.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr1_-_79440039 1.345 ENSMUST00000049972.4
Scg2
secretogranin II
chr1_-_22315792 1.318 ENSMUST00000164877.1
Rims1
regulating synaptic membrane exocytosis 1
chr8_+_107031218 1.314 ENSMUST00000034388.9
Vps4a
vacuolar protein sorting 4a (yeast)
chr9_-_103222063 1.308 ENSMUST00000170904.1
Trf
transferrin
chr3_+_62419668 1.292 ENSMUST00000161057.1
Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr15_-_67113909 1.292 ENSMUST00000092640.5
St3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr5_+_121777929 1.253 ENSMUST00000160821.1
Atxn2
ataxin 2
chr19_+_25672408 1.247 ENSMUST00000053068.5
Dmrt2
doublesex and mab-3 related transcription factor 2
chr16_-_45724600 1.243 ENSMUST00000096057.4
Tagln3
transgelin 3
chr12_+_38781093 1.204 ENSMUST00000161513.1
Etv1
ets variant gene 1
chr5_+_81021583 1.193 ENSMUST00000121707.1
Lphn3
latrophilin 3
chr3_+_86070915 1.188 ENSMUST00000182666.1
Sh3d19
SH3 domain protein D19
chr11_-_20332654 1.179 ENSMUST00000004634.6
Slc1a4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr1_-_126830632 1.175 ENSMUST00000112583.1
ENSMUST00000094609.3
Nckap5

NCK-associated protein 5

chr3_-_127225847 1.173 ENSMUST00000182726.1
ENSMUST00000182779.1
Ank2

ankyrin 2, brain

chr11_-_20332689 1.173 ENSMUST00000109594.1
Slc1a4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr13_-_102906046 1.160 ENSMUST00000171791.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr1_-_152625212 1.153 ENSMUST00000027760.7
Rgl1
ral guanine nucleotide dissociation stimulator,-like 1
chr3_+_109573907 1.150 ENSMUST00000106576.2
Vav3
vav 3 oncogene
chr2_-_77519565 1.142 ENSMUST00000111830.2
Zfp385b
zinc finger protein 385B
chr6_+_37870786 1.133 ENSMUST00000120428.1
ENSMUST00000031859.7
Trim24

tripartite motif-containing 24

chr10_+_127420867 1.131 ENSMUST00000064793.6
R3hdm2
R3H domain containing 2
chr19_-_14598031 1.128 ENSMUST00000167776.2
Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr19_-_14597983 1.127 ENSMUST00000052011.7
Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr4_-_129261394 1.120 ENSMUST00000145261.1
C77080
expressed sequence C77080
chr3_-_127225917 1.119 ENSMUST00000182064.1
ENSMUST00000182662.1
Ank2

ankyrin 2, brain

chr10_+_127421124 1.073 ENSMUST00000170336.1
R3hdm2
R3H domain containing 2
chrM_+_7759 1.068 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr18_-_24603464 1.061 ENSMUST00000154205.1
Slc39a6
solute carrier family 39 (metal ion transporter), member 6
chr13_-_113663670 1.061 ENSMUST00000054650.4
Hspb3
heat shock protein 3
chr4_-_155056784 1.053 ENSMUST00000131173.2
Plch2
phospholipase C, eta 2
chr5_+_88583527 1.030 ENSMUST00000031229.6
Rufy3
RUN and FYVE domain containing 3
chr12_+_55598917 1.027 ENSMUST00000051857.3
Insm2
insulinoma-associated 2
chr12_-_40037387 1.023 ENSMUST00000146905.1
Arl4a
ADP-ribosylation factor-like 4A
chr15_-_33687840 1.002 ENSMUST00000042021.3
Tspyl5
testis-specific protein, Y-encoded-like 5
chr5_+_29195983 0.999 ENSMUST00000160888.1
ENSMUST00000159272.1
ENSMUST00000001247.5
ENSMUST00000161398.1
ENSMUST00000160246.1
Rnf32




ring finger protein 32




chr13_-_114458720 0.990 ENSMUST00000022287.5
Fst
follistatin
chr2_+_121956651 0.981 ENSMUST00000110574.1
Ctdspl2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr2_-_5676046 0.976 ENSMUST00000114987.3
Camk1d
calcium/calmodulin-dependent protein kinase ID
chr2_+_65930117 0.970 ENSMUST00000176109.1
Csrnp3
cysteine-serine-rich nuclear protein 3
chr14_-_36919314 0.955 ENSMUST00000182797.1
Ccser2
coiled-coil serine rich 2
chr16_-_37384940 0.954 ENSMUST00000114781.1
ENSMUST00000114780.1
Stxbp5l

syntaxin binding protein 5-like

chr1_-_132390301 0.931 ENSMUST00000132435.1
Tmcc2
transmembrane and coiled-coil domains 2
chr18_+_24603952 0.920 ENSMUST00000025120.6
Elp2
elongator acetyltransferase complex subunit 2
chr2_+_69897255 0.914 ENSMUST00000131553.1
Ubr3
ubiquitin protein ligase E3 component n-recognin 3
chr5_+_19907774 0.898 ENSMUST00000115267.2
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr14_-_88471396 0.895 ENSMUST00000061628.5
Pcdh20
protocadherin 20
chr19_-_29334646 0.874 ENSMUST00000044143.5
Rln1
relaxin 1
chr11_-_107337556 0.865 ENSMUST00000040380.6
Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chr4_+_150853919 0.860 ENSMUST00000073600.2
Errfi1
ERBB receptor feedback inhibitor 1
chr9_+_45370185 0.833 ENSMUST00000085939.6
Fxyd6
FXYD domain-containing ion transport regulator 6
chr9_-_16378231 0.831 ENSMUST00000082170.5
Fat3
FAT tumor suppressor homolog 3 (Drosophila)
chr8_+_4238815 0.821 ENSMUST00000003027.7
ENSMUST00000110999.1
Map2k7

mitogen-activated protein kinase kinase 7

chr9_+_54980880 0.816 ENSMUST00000093844.3
Chrna5
cholinergic receptor, nicotinic, alpha polypeptide 5
chr11_-_87359011 0.799 ENSMUST00000055438.4
Ppm1e
protein phosphatase 1E (PP2C domain containing)
chr13_-_102905740 0.799 ENSMUST00000167462.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr17_-_29888570 0.794 ENSMUST00000171691.1
Mdga1
MAM domain containing glycosylphosphatidylinositol anchor 1
chr10_+_127420334 0.784 ENSMUST00000171434.1
R3hdm2
R3H domain containing 2
chr17_-_90088343 0.775 ENSMUST00000173917.1
Nrxn1
neurexin I
chr16_-_97170707 0.769 ENSMUST00000056102.7
Dscam
Down syndrome cell adhesion molecule
chr2_+_121956411 0.769 ENSMUST00000110578.1
Ctdspl2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr4_-_14621494 0.768 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chr3_+_125404072 0.757 ENSMUST00000173932.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr1_-_126830786 0.754 ENSMUST00000162646.1
Nckap5
NCK-associated protein 5
chr11_+_23306910 0.739 ENSMUST00000137823.1
Usp34
ubiquitin specific peptidase 34
chr10_-_117148474 0.737 ENSMUST00000020381.3
Frs2
fibroblast growth factor receptor substrate 2
chr2_-_64975762 0.733 ENSMUST00000156765.1
Grb14
growth factor receptor bound protein 14
chr3_-_88425094 0.729 ENSMUST00000168755.1
ENSMUST00000057935.6
Slc25a44

solute carrier family 25, member 44

chr10_+_99263224 0.722 ENSMUST00000020118.4
Dusp6
dual specificity phosphatase 6
chr15_-_77956658 0.720 ENSMUST00000117725.1
ENSMUST00000016696.6
Foxred2

FAD-dependent oxidoreductase domain containing 2

chr16_-_92400067 0.715 ENSMUST00000023672.8
Rcan1
regulator of calcineurin 1
chr4_-_14621805 0.709 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr2_-_164171113 0.706 ENSMUST00000045196.3
Kcns1
K+ voltage-gated channel, subfamily S, 1
chr2_-_37359274 0.701 ENSMUST00000009174.8
Pdcl
phosducin-like
chr3_+_121967822 0.699 ENSMUST00000137089.1
Arhgap29
Rho GTPase activating protein 29
chr13_+_83732438 0.686 ENSMUST00000182701.1
C130071C03Rik
RIKEN cDNA C130071C03 gene
chr4_-_14621669 0.678 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr3_-_116253467 0.661 ENSMUST00000090473.5
Gpr88
G-protein coupled receptor 88
chr4_+_13751297 0.659 ENSMUST00000105566.2
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr15_-_81360739 0.657 ENSMUST00000023040.7
Slc25a17
solute carrier family 25 (mitochondrial carrier, peroxisomal membrane protein), member 17
chrX_+_159708593 0.646 ENSMUST00000080394.6
Sh3kbp1
SH3-domain kinase binding protein 1
chr5_+_66968559 0.641 ENSMUST00000127184.1
Limch1
LIM and calponin homology domains 1
chr10_+_116018213 0.637 ENSMUST00000063470.4
Ptprr
protein tyrosine phosphatase, receptor type, R
chr10_+_73821857 0.629 ENSMUST00000177128.1
ENSMUST00000064562.7
ENSMUST00000129404.2
ENSMUST00000105426.3
ENSMUST00000131321.2
ENSMUST00000126920.2
ENSMUST00000147189.2
ENSMUST00000105424.3
ENSMUST00000092420.6
ENSMUST00000105429.3
ENSMUST00000131724.2
ENSMUST00000152655.2
ENSMUST00000151116.2
ENSMUST00000155701.2
ENSMUST00000152819.2
ENSMUST00000125517.2
ENSMUST00000124046.1
ENSMUST00000149977.2
ENSMUST00000146682.1
ENSMUST00000177107.1
Pcdh15



















protocadherin 15



















chr3_+_13946368 0.626 ENSMUST00000171075.1
ENSMUST00000108372.2
Ralyl

RALY RNA binding protein-like

chr7_+_126950837 0.625 ENSMUST00000106332.1
Sez6l2
seizure related 6 homolog like 2
chr18_-_24603791 0.619 ENSMUST00000070726.3
Slc39a6
solute carrier family 39 (metal ion transporter), member 6
chr15_+_81936911 0.609 ENSMUST00000135663.1
Csdc2
cold shock domain containing C2, RNA binding
chr7_-_99141068 0.600 ENSMUST00000037968.8
Uvrag
UV radiation resistance associated gene
chr14_-_108914237 0.593 ENSMUST00000100322.2
Slitrk1
SLIT and NTRK-like family, member 1
chr6_-_56923927 0.588 ENSMUST00000031793.5
Nt5c3
5'-nucleotidase, cytosolic III
chr18_+_66458587 0.586 ENSMUST00000025399.7
Pmaip1
phorbol-12-myristate-13-acetate-induced protein 1
chr19_+_11965817 0.583 ENSMUST00000025590.9
Osbp
oxysterol binding protein
chr5_+_19907502 0.580 ENSMUST00000101558.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr5_+_144100387 0.575 ENSMUST00000041804.7
Lmtk2
lemur tyrosine kinase 2
chr6_-_126645784 0.574 ENSMUST00000055168.3
Kcna1
potassium voltage-gated channel, shaker-related subfamily, member 1
chr4_+_65604984 0.572 ENSMUST00000050850.7
ENSMUST00000107366.1
Trim32

tripartite motif-containing 32

chr11_-_102897123 0.570 ENSMUST00000067444.3
Gfap
glial fibrillary acidic protein
chrX_-_150814265 0.568 ENSMUST00000026302.6
ENSMUST00000129768.1
ENSMUST00000112699.2
Maged2


melanoma antigen, family D, 2


chr7_+_79273201 0.563 ENSMUST00000037315.6
Abhd2
abhydrolase domain containing 2
chr6_+_30541582 0.537 ENSMUST00000096066.4
Cpa2
carboxypeptidase A2, pancreatic
chr18_+_37819543 0.521 ENSMUST00000055935.5
Pcdhga9
protocadherin gamma subfamily A, 9
chrX_+_151803313 0.512 ENSMUST00000026292.8
Huwe1
HECT, UBA and WWE domain containing 1
chr12_+_72441933 0.507 ENSMUST00000161284.1
Lrrc9
leucine rich repeat containing 9
chr15_+_81936753 0.506 ENSMUST00000038757.7
Csdc2
cold shock domain containing C2, RNA binding
chr2_-_45110241 0.505 ENSMUST00000177302.1
Zeb2
zinc finger E-box binding homeobox 2
chr6_+_29859662 0.498 ENSMUST00000128927.2
Ahcyl2
S-adenosylhomocysteine hydrolase-like 2
chr15_+_82252397 0.492 ENSMUST00000136948.1
1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr8_-_54724474 0.491 ENSMUST00000175915.1
Wdr17
WD repeat domain 17
chr2_+_69897220 0.491 ENSMUST00000055758.9
ENSMUST00000112251.2
Ubr3

ubiquitin protein ligase E3 component n-recognin 3

chr18_+_30272747 0.491 ENSMUST00000115812.3
ENSMUST00000115811.1
ENSMUST00000091978.5
Pik3c3


phosphoinositide-3-kinase, class 3


chr1_+_180109192 0.488 ENSMUST00000143176.1
ENSMUST00000135056.1
Cdc42bpa

CDC42 binding protein kinase alpha

chr16_-_89818338 0.483 ENSMUST00000164263.2
Tiam1
T cell lymphoma invasion and metastasis 1
chr15_-_37458523 0.480 ENSMUST00000116445.2
Ncald
neurocalcin delta
chr6_+_29859686 0.479 ENSMUST00000134438.1
Ahcyl2
S-adenosylhomocysteine hydrolase-like 2
chr5_-_70842617 0.478 ENSMUST00000031119.1
Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr2_+_155382186 0.469 ENSMUST00000134218.1
Trp53inp2
transformation related protein 53 inducible nuclear protein 2
chr4_-_35845204 0.463 ENSMUST00000164772.1
ENSMUST00000065173.2
Lingo2

leucine rich repeat and Ig domain containing 2

chr6_-_122340499 0.450 ENSMUST00000160843.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr16_-_22857514 0.445 ENSMUST00000004576.6
Tbccd1
TBCC domain containing 1
chr2_-_33086366 0.444 ENSMUST00000049618.2
Garnl3
GTPase activating RANGAP domain-like 3
chr7_+_123123870 0.437 ENSMUST00000094053.5
Tnrc6a
trinucleotide repeat containing 6a
chr8_+_83666827 0.436 ENSMUST00000019608.5
Ptger1
prostaglandin E receptor 1 (subtype EP1)
chr1_-_155417283 0.434 ENSMUST00000027741.5
Xpr1
xenotropic and polytropic retrovirus receptor 1
chr19_-_46969474 0.431 ENSMUST00000086961.7
Nt5c2
5'-nucleotidase, cytosolic II
chr2_-_45117349 0.429 ENSMUST00000176438.2
Zeb2
zinc finger E-box binding homeobox 2
chr7_+_3645267 0.424 ENSMUST00000038913.9
Cnot3
CCR4-NOT transcription complex, subunit 3
chr19_-_4698668 0.423 ENSMUST00000177696.1
Gm960
predicted gene 960
chr7_+_64502090 0.408 ENSMUST00000137732.1
Apba2
amyloid beta (A4) precursor protein-binding, family A, member 2
chr3_+_94837533 0.407 ENSMUST00000107270.2
Pogz
pogo transposable element with ZNF domain
chr14_-_37098211 0.398 ENSMUST00000022337.9
Cdhr1
cadherin-related family member 1
chr14_+_111675113 0.398 ENSMUST00000042767.7
Slitrk5
SLIT and NTRK-like family, member 5
chrX_+_23693043 0.396 ENSMUST00000035766.6
ENSMUST00000101670.2
Wdr44

WD repeat domain 44

chr12_-_87388317 0.396 ENSMUST00000021424.4
Sptlc2
serine palmitoyltransferase, long chain base subunit 2
chr15_-_58214882 0.394 ENSMUST00000022986.6
Fbxo32
F-box protein 32
chr9_-_120068263 0.393 ENSMUST00000064165.3
ENSMUST00000177637.1
Cx3cr1

chemokine (C-X3-C) receptor 1

chr3_+_125404292 0.390 ENSMUST00000144344.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr17_-_24073479 0.387 ENSMUST00000017090.5
Kctd5
potassium channel tetramerisation domain containing 5

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.6 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.6 1.8 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.6 1.8 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.6 2.4 GO:0015825 L-serine transport(GO:0015825)
0.5 2.2 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.5 1.6 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.5 1.5 GO:0071336 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.5 3.0 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) phosphate ion transmembrane transport(GO:0035435) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.5 5.4 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.5 2.8 GO:0016198 axon choice point recognition(GO:0016198)
0.5 1.4 GO:0001543 ovarian follicle rupture(GO:0001543)
0.5 6.4 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.4 1.3 GO:0009838 abscission(GO:0009838) positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.4 2.5 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.4 3.7 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.4 3.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.4 1.4 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.3 1.3 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.3 2.2 GO:0019532 oxalate transport(GO:0019532)
0.3 0.6 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.3 2.0 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091) negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.3 0.9 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.3 2.3 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.3 6.8 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.3 1.1 GO:0061055 myotome development(GO:0061055)
0.3 1.3 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.3 0.8 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.3 2.3 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.2 0.7 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.2 0.7 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.2 0.7 GO:1902605 heterotrimeric G-protein complex assembly(GO:1902605)
0.2 0.7 GO:0061743 motor learning(GO:0061743)
0.2 0.9 GO:0010749 regulation of nitric oxide mediated signal transduction(GO:0010749)
0.2 1.0 GO:0051684 maintenance of Golgi location(GO:0051684)
0.2 0.8 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.2 0.4 GO:0002677 negative regulation of chronic inflammatory response(GO:0002677)
0.2 0.6 GO:0050975 sensory perception of touch(GO:0050975)
0.2 1.1 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.2 2.8 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.2 1.3 GO:0098707 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.2 0.5 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.2 0.5 GO:1900149 positive regulation of Schwann cell migration(GO:1900149)
0.2 4.3 GO:0008340 determination of adult lifespan(GO:0008340)
0.2 0.6 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.2 1.7 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 0.6 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 1.0 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.1 0.4 GO:0006667 sphinganine metabolic process(GO:0006667) regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.1 0.7 GO:0015867 ATP transport(GO:0015867)
0.1 0.4 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 1.0 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 0.6 GO:0070627 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692) ferrous iron import(GO:0070627)
0.1 0.3 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.1 3.7 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 3.1 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.1 0.4 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.1 1.0 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.5 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 0.6 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
0.1 0.6 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.1 1.0 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.1 0.8 GO:0035095 behavioral response to nicotine(GO:0035095)
0.1 2.8 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.1 0.3 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.1 0.3 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.1 0.4 GO:0060690 epithelial cell differentiation involved in salivary gland development(GO:0060690)
0.1 0.6 GO:0050957 equilibrioception(GO:0050957)
0.1 0.6 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 3.0 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 0.2 GO:2000510 positive regulation of dendritic cell chemotaxis(GO:2000510)
0.1 3.9 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 1.4 GO:0001553 luteinization(GO:0001553)
0.1 0.4 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.1 5.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 1.0 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.1 1.3 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.1 0.6 GO:0032570 response to progesterone(GO:0032570)
0.1 1.1 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.1 0.3 GO:0006689 ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.1 0.2 GO:0090370 negative regulation of cholesterol efflux(GO:0090370) positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.1 0.2 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.1 0.2 GO:0046878 corticosterone secretion(GO:0035934) positive regulation of saliva secretion(GO:0046878) positive regulation of glucocorticoid secretion(GO:2000851) regulation of corticosterone secretion(GO:2000852)
0.1 0.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.1 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.1 1.8 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 1.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.6 GO:0044144 regulation of growth of symbiont in host(GO:0044126) modulation of growth of symbiont involved in interaction with host(GO:0044144)
0.0 0.8 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.1 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.7 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 0.6 GO:0033572 transferrin transport(GO:0033572)
0.0 1.3 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.1 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.0 1.1 GO:2000726 negative regulation of cardiac muscle cell differentiation(GO:2000726)
0.0 1.7 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.2 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.7 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 0.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 1.7 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 1.8 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 1.0 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 1.0 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.7 GO:0006839 mitochondrial transport(GO:0006839)
0.0 0.3 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 1.3 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.3 GO:1904861 excitatory synapse assembly(GO:1904861)
0.0 2.7 GO:0030168 platelet activation(GO:0030168)
0.0 3.0 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.5 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.3 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 3.0 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.1 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.4 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.9 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 1.0 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.3 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.3 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 2.9 GO:0007416 synapse assembly(GO:0007416)
0.0 2.4 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.1 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 2.3 GO:0030048 actin filament-based movement(GO:0030048)
0.0 0.9 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 0.2 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.2 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 1.9 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 0.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.3 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.4 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.0 0.3 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.0 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 1.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.7 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.2 GO:0045332 phospholipid translocation(GO:0045332)
0.0 1.9 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.1 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0 0.3 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 1.0 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.5 GO:0006284 base-excision repair(GO:0006284)
0.0 0.8 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.2 GO:0070584 mitochondrion morphogenesis(GO:0070584)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.8 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.5 2.6 GO:0033093 Weibel-Palade body(GO:0033093)
0.5 2.0 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.4 6.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.3 0.6 GO:0005859 muscle myosin complex(GO:0005859)
0.3 1.7 GO:0031258 lamellipodium membrane(GO:0031258)
0.3 1.3 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.3 2.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 5.9 GO:0071565 nBAF complex(GO:0071565)
0.2 1.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.2 1.4 GO:0097433 dense body(GO:0097433)
0.2 0.5 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.2 2.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 1.3 GO:0090543 Flemming body(GO:0090543)
0.1 2.2 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.6 GO:0097450 astrocyte end-foot(GO:0097450)
0.1 2.8 GO:0031527 filopodium membrane(GO:0031527)
0.1 0.9 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 5.6 GO:0031672 A band(GO:0031672)
0.1 0.6 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.7 GO:0071437 invadopodium(GO:0071437)
0.1 0.6 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 1.3 GO:0031045 dense core granule(GO:0031045)
0.1 1.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.3 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.1 0.8 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 2.4 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.5 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.4 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 0.6 GO:0001739 sex chromatin(GO:0001739)
0.1 2.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 0.5 GO:0060091 kinocilium(GO:0060091)
0.1 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 1.8 GO:0030673 axolemma(GO:0030673)
0.1 0.3 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 0.4 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.1 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.4 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 2.4 GO:0005882 intermediate filament(GO:0005882)
0.0 0.3 GO:0005916 fascia adherens(GO:0005916)
0.0 0.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 2.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.9 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.8 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.7 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 1.0 GO:0016235 aggresome(GO:0016235)
0.0 1.5 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 3.5 GO:0001650 fibrillar center(GO:0001650)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 1.0 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.3 GO:0098644 complex of collagen trimers(GO:0098644)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.3 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.4 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.7 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.6 GO:0045335 phagocytic vesicle(GO:0045335)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.9 3.7 GO:0004966 galanin receptor activity(GO:0004966)
0.4 3.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.4 4.0 GO:0019865 immunoglobulin binding(GO:0019865)
0.4 3.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.4 1.5 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.3 1.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.3 2.4 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) L-proline transmembrane transporter activity(GO:0015193) alanine transmembrane transporter activity(GO:0022858)
0.3 2.2 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.2 1.5 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 0.7 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.2 1.0 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.2 1.8 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 2.2 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.2 1.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.2 1.3 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.2 1.3 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.2 3.6 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.2 1.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.2 1.1 GO:0034056 estrogen response element binding(GO:0034056)
0.2 1.8 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 2.0 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.4 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.7 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.1 0.7 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.6 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.7 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 0.4 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.6 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 0.3 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 1.0 GO:0048185 activin binding(GO:0048185)
0.1 0.4 GO:0004954 icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)
0.1 2.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.8 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.9 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.4 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.1 2.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 1.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 1.3 GO:0042056 chemoattractant activity(GO:0042056)
0.1 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.8 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 1.0 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 3.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 1.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.1 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 0.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 2.3 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.2 GO:0036004 GAF domain binding(GO:0036004)
0.1 2.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 0.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.6 GO:0035004 1-phosphatidylinositol-3-kinase activity(GO:0016303) phosphatidylinositol 3-kinase activity(GO:0035004)
0.0 1.4 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 2.6 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.5 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.6 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 10.5 GO:0008017 microtubule binding(GO:0008017)
0.0 0.4 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.8 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 3.0 GO:0002039 p53 binding(GO:0002039)
0.0 0.9 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.4 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 2.8 GO:0019905 syntaxin binding(GO:0019905)
0.0 2.3 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 1.0 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 1.7 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 1.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 3.1 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.9 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.5 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 3.7 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.3 GO:0017166 vinculin binding(GO:0017166)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.3 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.2 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 1.1 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 2.0 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.0 0.6 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.7 GO:0005179 hormone activity(GO:0005179)
0.0 1.4 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 2.8 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.4 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 2.4 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.3 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.7 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 4.4 GO:0005509 calcium ion binding(GO:0005509)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.6 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 6.1 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 3.7 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.1 1.6 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.1 3.2 PID_REELIN_PATHWAY Reelin signaling pathway
0.1 0.9 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.1 4.2 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 4.8 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.1 1.4 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.0 2.1 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.7 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.1 PID_BMP_PATHWAY BMP receptor signaling
0.0 0.2 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 0.6 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 0.7 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.2 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.4 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.8 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.7 PID_INSULIN_PATHWAY Insulin Pathway
0.0 0.6 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.2 PID_CXCR4_PATHWAY CXCR4-mediated signaling events
0.0 0.3 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.4 PID_FOXO_PATHWAY FoxO family signaling
0.0 0.6 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 0.8 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.6 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.2 0.2 REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING Genes involved in SHC1 events in EGFR signaling
0.2 5.9 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.4 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 1.3 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 2.8 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.3 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 0.8 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 1.7 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.1 2.5 REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 2.4 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 0.6 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.1 1.0 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.1 1.6 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.1 4.3 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 0.8 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.0 0.7 REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS Genes involved in Prolonged ERK activation events
0.0 0.4 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.0 5.8 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions
0.0 1.0 REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 1.1 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.8 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.0 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.7 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 1.3 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 1.5 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.1 REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.8 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 1.3 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.5 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.6 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.1 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.8 REACTOME_PEROXISOMAL_LIPID_METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.3 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.9 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.0 1.0 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.2 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.2 REACTOME_VITAMIN_B5_PANTOTHENATE_METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.4 REACTOME_REGULATORY_RNA_PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.6 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.4 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.4 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.5 REACTOME_ADP_SIGNALLING_THROUGH_P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.3 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.1 REACTOME_ACYL_CHAIN_REMODELLING_OF_PI Genes involved in Acyl chain remodelling of PI