Motif ID: Gcm2
Z-value: 2.029
Transcription factors associated with Gcm2:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Gcm2 | ENSMUSG00000021362.6 | Gcm2 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 25.8 | 77.5 | GO:0032430 | inhibitory G-protein coupled receptor phosphorylation(GO:0002030) positive regulation of phospholipase A2 activity(GO:0032430) activation of meiosis involved in egg activation(GO:0060466) |
| 3.3 | 23.3 | GO:0016185 | synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) |
| 3.3 | 9.8 | GO:0007621 | negative regulation of female receptivity(GO:0007621) |
| 2.4 | 2.4 | GO:0071895 | odontoblast differentiation(GO:0071895) |
| 2.3 | 9.3 | GO:0045113 | regulation of integrin biosynthetic process(GO:0045113) |
| 2.1 | 6.4 | GO:0021577 | hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) |
| 2.1 | 6.3 | GO:0051892 | negative regulation of cardioblast differentiation(GO:0051892) |
| 2.0 | 6.0 | GO:0035934 | corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852) |
| 1.9 | 7.7 | GO:0061526 | acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) acetylcholine secretion(GO:0061526) |
| 1.9 | 9.3 | GO:0045347 | negative regulation of MHC class II biosynthetic process(GO:0045347) |
| 1.7 | 5.2 | GO:0043181 | vacuolar sequestering(GO:0043181) |
| 1.7 | 6.7 | GO:0042138 | meiotic DNA double-strand break formation(GO:0042138) |
| 1.6 | 4.9 | GO:0035585 | calcium-mediated signaling using extracellular calcium source(GO:0035585) |
| 1.6 | 11.1 | GO:2000124 | regulation of endocannabinoid signaling pathway(GO:2000124) |
| 1.5 | 6.2 | GO:1901252 | regulation of intracellular transport of viral material(GO:1901252) |
| 1.5 | 10.7 | GO:1990416 | cellular response to brain-derived neurotrophic factor stimulus(GO:1990416) |
| 1.5 | 4.6 | GO:0046462 | monoacylglycerol metabolic process(GO:0046462) |
| 1.5 | 4.6 | GO:1903903 | regulation of establishment of T cell polarity(GO:1903903) |
| 1.5 | 7.6 | GO:2001025 | positive regulation of response to drug(GO:2001025) |
| 1.5 | 4.5 | GO:0032915 | positive regulation of transforming growth factor beta2 production(GO:0032915) |
| 1.4 | 1.4 | GO:0061153 | trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) |
| 1.4 | 5.8 | GO:0050955 | thermoception(GO:0050955) |
| 1.4 | 7.0 | GO:0007197 | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207) |
| 1.4 | 1.4 | GO:0003274 | endocardial cushion fusion(GO:0003274) |
| 1.4 | 8.3 | GO:2000298 | regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298) |
| 1.3 | 3.9 | GO:0061144 | alveolar secondary septum development(GO:0061144) |
| 1.3 | 6.4 | GO:0015671 | oxygen transport(GO:0015671) |
| 1.3 | 7.6 | GO:1990573 | potassium ion import across plasma membrane(GO:1990573) |
| 1.3 | 11.4 | GO:0071420 | cellular response to histamine(GO:0071420) |
| 1.3 | 5.0 | GO:0014012 | peripheral nervous system axon regeneration(GO:0014012) |
| 1.2 | 1.2 | GO:0036023 | limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023) |
| 1.2 | 4.9 | GO:0086046 | membrane depolarization during SA node cell action potential(GO:0086046) |
| 1.2 | 6.1 | GO:0043314 | negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313) |
| 1.2 | 4.7 | GO:0002924 | negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924) |
| 1.2 | 5.9 | GO:0051012 | microtubule sliding(GO:0051012) |
| 1.1 | 1.1 | GO:0060137 | maternal process involved in parturition(GO:0060137) |
| 1.1 | 3.3 | GO:0071492 | cellular response to UV-A(GO:0071492) |
| 1.1 | 3.3 | GO:0019401 | alditol biosynthetic process(GO:0019401) |
| 1.1 | 6.4 | GO:2001204 | regulation of osteoclast development(GO:2001204) |
| 1.0 | 3.0 | GO:0030827 | negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283) |
| 1.0 | 3.9 | GO:0021564 | glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564) |
| 1.0 | 5.8 | GO:0097646 | calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647) |
| 1.0 | 3.8 | GO:0003011 | involuntary skeletal muscle contraction(GO:0003011) |
| 1.0 | 2.9 | GO:0061588 | calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591) |
| 0.9 | 4.7 | GO:0009074 | aromatic amino acid family catabolic process(GO:0009074) |
| 0.9 | 5.6 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
| 0.9 | 2.8 | GO:1903630 | regulation of aminoacyl-tRNA ligase activity(GO:1903630) positive regulation of aminoacyl-tRNA ligase activity(GO:1903632) |
| 0.9 | 5.3 | GO:0048069 | eye pigmentation(GO:0048069) |
| 0.9 | 5.1 | GO:0046103 | inosine biosynthetic process(GO:0046103) |
| 0.8 | 6.7 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
| 0.8 | 3.4 | GO:0050913 | sensory perception of bitter taste(GO:0050913) |
| 0.8 | 6.7 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
| 0.8 | 8.3 | GO:0033631 | cell-cell adhesion mediated by integrin(GO:0033631) |
| 0.8 | 3.3 | GO:2000017 | positive regulation of determination of dorsal identity(GO:2000017) |
| 0.8 | 3.2 | GO:0090126 | protein complex assembly involved in synapse maturation(GO:0090126) |
| 0.8 | 2.4 | GO:0035799 | ureter maturation(GO:0035799) |
| 0.8 | 4.0 | GO:1902031 | regulation of NADP metabolic process(GO:1902031) |
| 0.8 | 2.4 | GO:1904059 | positive regulation of sensory perception of pain(GO:1904058) regulation of locomotor rhythm(GO:1904059) |
| 0.8 | 3.2 | GO:0098912 | smooth muscle contraction involved in micturition(GO:0060083) membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) |
| 0.8 | 5.5 | GO:0060267 | positive regulation of respiratory burst(GO:0060267) |
| 0.8 | 2.3 | GO:0072061 | inner medullary collecting duct development(GO:0072061) |
| 0.8 | 2.3 | GO:0070343 | white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350) |
| 0.8 | 2.3 | GO:0001193 | maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193) |
| 0.8 | 1.5 | GO:0070671 | response to interleukin-12(GO:0070671) |
| 0.7 | 5.1 | GO:0098915 | membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915) |
| 0.7 | 2.2 | GO:0045163 | clustering of voltage-gated potassium channels(GO:0045163) |
| 0.7 | 2.1 | GO:0031529 | ruffle organization(GO:0031529) |
| 0.7 | 2.1 | GO:1903538 | meiotic sister chromatid cohesion, centromeric(GO:0051754) meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538) |
| 0.7 | 2.8 | GO:0006586 | tryptophan metabolic process(GO:0006568) indolalkylamine metabolic process(GO:0006586) |
| 0.7 | 3.5 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
| 0.7 | 2.1 | GO:0097274 | urea homeostasis(GO:0097274) |
| 0.7 | 2.0 | GO:0009826 | unidimensional cell growth(GO:0009826) susceptibility to natural killer cell mediated cytotoxicity(GO:0042271) |
| 0.7 | 7.3 | GO:0032482 | Rab protein signal transduction(GO:0032482) |
| 0.7 | 6.0 | GO:0060907 | positive regulation of macrophage cytokine production(GO:0060907) |
| 0.7 | 3.3 | GO:2000255 | negative regulation of male germ cell proliferation(GO:2000255) |
| 0.7 | 2.0 | GO:0009414 | response to water deprivation(GO:0009414) |
| 0.6 | 5.2 | GO:0098967 | exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967) |
| 0.6 | 3.8 | GO:0030432 | peristalsis(GO:0030432) |
| 0.6 | 5.7 | GO:1903874 | ferrous iron transmembrane transport(GO:1903874) |
| 0.6 | 3.8 | GO:0071415 | cellular response to purine-containing compound(GO:0071415) |
| 0.6 | 11.7 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
| 0.6 | 1.8 | GO:0071638 | negative regulation of monocyte chemotactic protein-1 production(GO:0071638) |
| 0.6 | 2.4 | GO:0044861 | protein transport into plasma membrane raft(GO:0044861) |
| 0.6 | 4.8 | GO:0071372 | cellular response to follicle-stimulating hormone stimulus(GO:0071372) |
| 0.6 | 11.9 | GO:1901897 | regulation of relaxation of cardiac muscle(GO:1901897) |
| 0.6 | 15.9 | GO:0071625 | vocalization behavior(GO:0071625) |
| 0.6 | 0.6 | GO:0044830 | modulation by host of viral RNA genome replication(GO:0044830) |
| 0.6 | 4.1 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 0.6 | 4.1 | GO:0032782 | bile acid secretion(GO:0032782) positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360) |
| 0.6 | 4.0 | GO:0060666 | dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666) |
| 0.6 | 1.7 | GO:0042536 | negative regulation of tumor necrosis factor biosynthetic process(GO:0042536) |
| 0.6 | 2.8 | GO:0070164 | negative regulation of adiponectin secretion(GO:0070164) |
| 0.5 | 2.7 | GO:0070986 | left/right axis specification(GO:0070986) |
| 0.5 | 1.6 | GO:0006667 | sphinganine metabolic process(GO:0006667) |
| 0.5 | 2.2 | GO:0016128 | phytosteroid metabolic process(GO:0016128) phytosteroid biosynthetic process(GO:0016129) |
| 0.5 | 1.6 | GO:0060120 | auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120) |
| 0.5 | 1.6 | GO:0010958 | regulation of amino acid import(GO:0010958) |
| 0.5 | 1.6 | GO:0071544 | diphosphoinositol polyphosphate catabolic process(GO:0071544) |
| 0.5 | 2.7 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
| 0.5 | 10.1 | GO:0001553 | luteinization(GO:0001553) |
| 0.5 | 4.8 | GO:2001256 | regulation of store-operated calcium entry(GO:2001256) |
| 0.5 | 3.7 | GO:0035093 | spermatogenesis, exchange of chromosomal proteins(GO:0035093) |
| 0.5 | 3.5 | GO:0051534 | negative regulation of NFAT protein import into nucleus(GO:0051534) |
| 0.5 | 3.0 | GO:0006071 | glycerol metabolic process(GO:0006071) cellular triglyceride homeostasis(GO:0035356) |
| 0.5 | 2.0 | GO:0043985 | histone H4-R3 methylation(GO:0043985) |
| 0.5 | 1.5 | GO:0019372 | lipoxygenase pathway(GO:0019372) |
| 0.5 | 1.0 | GO:0097155 | fasciculation of sensory neuron axon(GO:0097155) |
| 0.5 | 4.8 | GO:1900113 | negative regulation of histone H3-K9 trimethylation(GO:1900113) |
| 0.5 | 3.8 | GO:0045607 | regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980) |
| 0.5 | 1.9 | GO:0019276 | UDP-N-acetylgalactosamine metabolic process(GO:0019276) |
| 0.5 | 0.9 | GO:0075044 | autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071) |
| 0.5 | 3.7 | GO:0006477 | protein sulfation(GO:0006477) |
| 0.5 | 1.8 | GO:0048298 | positive regulation of isotype switching to IgA isotypes(GO:0048298) |
| 0.4 | 3.1 | GO:0007195 | adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195) |
| 0.4 | 1.3 | GO:0072076 | nephrogenic mesenchyme development(GO:0072076) |
| 0.4 | 1.7 | GO:0061739 | protein lipidation involved in autophagosome assembly(GO:0061739) |
| 0.4 | 2.6 | GO:0032796 | uropod organization(GO:0032796) |
| 0.4 | 0.4 | GO:0033122 | regulation of purine nucleotide catabolic process(GO:0033121) negative regulation of purine nucleotide catabolic process(GO:0033122) |
| 0.4 | 1.3 | GO:0006659 | phosphatidylserine biosynthetic process(GO:0006659) |
| 0.4 | 3.4 | GO:1900121 | negative regulation of receptor binding(GO:1900121) |
| 0.4 | 4.2 | GO:1903025 | regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025) |
| 0.4 | 1.3 | GO:0001180 | transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180) |
| 0.4 | 1.3 | GO:1904046 | seryl-tRNA aminoacylation(GO:0006434) negative regulation of vascular endothelial growth factor production(GO:1904046) |
| 0.4 | 10.4 | GO:0048148 | behavioral response to cocaine(GO:0048148) |
| 0.4 | 3.8 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 0.4 | 0.4 | GO:0042776 | mitochondrial ATP synthesis coupled proton transport(GO:0042776) |
| 0.4 | 2.8 | GO:0070471 | uterine smooth muscle contraction(GO:0070471) regulation of uterine smooth muscle contraction(GO:0070472) |
| 0.4 | 8.4 | GO:0060749 | mammary gland alveolus development(GO:0060749) mammary gland lobule development(GO:0061377) |
| 0.4 | 2.8 | GO:0030382 | sperm mitochondrion organization(GO:0030382) |
| 0.4 | 1.2 | GO:0070459 | prolactin secretion(GO:0070459) |
| 0.4 | 2.7 | GO:0061002 | negative regulation of dendritic spine morphogenesis(GO:0061002) |
| 0.4 | 0.4 | GO:0046166 | glyceraldehyde-3-phosphate biosynthetic process(GO:0046166) |
| 0.4 | 3.4 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.4 | 1.5 | GO:0007023 | post-chaperonin tubulin folding pathway(GO:0007023) |
| 0.4 | 3.7 | GO:0015824 | proline transport(GO:0015824) |
| 0.4 | 1.1 | GO:0071550 | death-inducing signaling complex assembly(GO:0071550) |
| 0.4 | 2.2 | GO:0018916 | nitrobenzene metabolic process(GO:0018916) |
| 0.4 | 0.7 | GO:0090427 | activation of meiosis(GO:0090427) |
| 0.4 | 1.4 | GO:0035247 | peptidyl-arginine omega-N-methylation(GO:0035247) |
| 0.4 | 5.6 | GO:0030204 | chondroitin sulfate metabolic process(GO:0030204) |
| 0.3 | 1.0 | GO:0090063 | positive regulation of microtubule nucleation(GO:0090063) |
| 0.3 | 0.7 | GO:0003199 | endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) cell proliferation involved in heart valve development(GO:2000793) |
| 0.3 | 2.1 | GO:0034227 | tRNA thio-modification(GO:0034227) |
| 0.3 | 0.7 | GO:2000664 | positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667) |
| 0.3 | 1.0 | GO:0002430 | complement receptor mediated signaling pathway(GO:0002430) |
| 0.3 | 2.7 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
| 0.3 | 2.4 | GO:0006561 | proline biosynthetic process(GO:0006561) |
| 0.3 | 1.0 | GO:1900149 | positive regulation of Schwann cell migration(GO:1900149) |
| 0.3 | 4.1 | GO:0061000 | negative regulation of dendritic spine development(GO:0061000) |
| 0.3 | 4.1 | GO:0048484 | enteric nervous system development(GO:0048484) |
| 0.3 | 5.7 | GO:2000251 | positive regulation of actin cytoskeleton reorganization(GO:2000251) |
| 0.3 | 20.8 | GO:0038083 | peptidyl-tyrosine autophosphorylation(GO:0038083) |
| 0.3 | 2.0 | GO:0071955 | recycling endosome to Golgi transport(GO:0071955) |
| 0.3 | 2.0 | GO:1901838 | positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838) |
| 0.3 | 0.7 | GO:0090204 | protein localization to nuclear pore(GO:0090204) |
| 0.3 | 1.6 | GO:0036324 | negative regulation of toll-like receptor 4 signaling pathway(GO:0034144) vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
| 0.3 | 2.6 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.3 | 7.9 | GO:0035455 | response to interferon-alpha(GO:0035455) |
| 0.3 | 4.3 | GO:0016486 | peptide hormone processing(GO:0016486) |
| 0.3 | 1.0 | GO:0090646 | mitochondrial tRNA processing(GO:0090646) |
| 0.3 | 0.7 | GO:0006507 | GPI anchor release(GO:0006507) |
| 0.3 | 1.6 | GO:0046684 | response to pyrethroid(GO:0046684) |
| 0.3 | 2.9 | GO:0031424 | keratinization(GO:0031424) |
| 0.3 | 1.0 | GO:0016998 | cell wall macromolecule catabolic process(GO:0016998) |
| 0.3 | 0.6 | GO:0003256 | regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003256) |
| 0.3 | 1.0 | GO:0042196 | dichloromethane metabolic process(GO:0018900) chlorinated hydrocarbon metabolic process(GO:0042196) halogenated hydrocarbon metabolic process(GO:0042197) |
| 0.3 | 14.5 | GO:0001881 | receptor recycling(GO:0001881) |
| 0.3 | 1.3 | GO:0006432 | phenylalanyl-tRNA aminoacylation(GO:0006432) |
| 0.3 | 4.1 | GO:2001135 | regulation of endocytic recycling(GO:2001135) |
| 0.3 | 3.5 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.3 | 5.2 | GO:0006465 | signal peptide processing(GO:0006465) |
| 0.3 | 3.1 | GO:1901096 | regulation of autophagosome maturation(GO:1901096) |
| 0.3 | 4.0 | GO:0033169 | histone H3-K9 demethylation(GO:0033169) |
| 0.3 | 1.2 | GO:0046898 | response to cycloheximide(GO:0046898) |
| 0.3 | 1.5 | GO:0036438 | maintenance of lens transparency(GO:0036438) |
| 0.3 | 1.5 | GO:0019695 | choline metabolic process(GO:0019695) |
| 0.3 | 0.6 | GO:0016115 | terpenoid catabolic process(GO:0016115) |
| 0.3 | 14.1 | GO:0034605 | cellular response to heat(GO:0034605) |
| 0.3 | 1.2 | GO:0044805 | late nucleophagy(GO:0044805) |
| 0.3 | 1.2 | GO:1901526 | positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925) |
| 0.3 | 1.2 | GO:0015015 | heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015) |
| 0.3 | 1.7 | GO:0098909 | regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909) |
| 0.3 | 5.4 | GO:0030431 | sleep(GO:0030431) |
| 0.3 | 4.0 | GO:2000009 | negative regulation of protein localization to cell surface(GO:2000009) |
| 0.3 | 0.3 | GO:0021798 | forebrain dorsal/ventral pattern formation(GO:0021798) |
| 0.3 | 1.4 | GO:0019348 | dolichol metabolic process(GO:0019348) |
| 0.3 | 2.5 | GO:0030259 | lipid glycosylation(GO:0030259) |
| 0.3 | 1.4 | GO:1904721 | regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721) |
| 0.3 | 3.3 | GO:1990440 | positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440) |
| 0.3 | 11.2 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
| 0.3 | 2.1 | GO:1905098 | negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098) |
| 0.3 | 1.8 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
| 0.3 | 4.9 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
| 0.3 | 0.8 | GO:0015886 | heme transport(GO:0015886) |
| 0.3 | 2.1 | GO:0097384 | cellular lipid biosynthetic process(GO:0097384) |
| 0.3 | 1.0 | GO:1902268 | negative regulation of polyamine transmembrane transport(GO:1902268) |
| 0.3 | 1.8 | GO:0042167 | porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149) |
| 0.3 | 1.3 | GO:1900748 | positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) |
| 0.3 | 0.5 | GO:1902287 | trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287) |
| 0.2 | 1.2 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
| 0.2 | 1.2 | GO:0090292 | nuclear migration along microfilament(GO:0031022) nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292) |
| 0.2 | 2.0 | GO:0035845 | photoreceptor cell outer segment organization(GO:0035845) |
| 0.2 | 0.7 | GO:0018199 | peptidyl-glutamine modification(GO:0018199) |
| 0.2 | 0.5 | GO:0002314 | germinal center B cell differentiation(GO:0002314) |
| 0.2 | 3.7 | GO:0042407 | cristae formation(GO:0042407) |
| 0.2 | 1.5 | GO:2001181 | positive regulation of interleukin-10 secretion(GO:2001181) |
| 0.2 | 1.2 | GO:2000325 | regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327) |
| 0.2 | 2.9 | GO:0060294 | cilium movement involved in cell motility(GO:0060294) |
| 0.2 | 0.7 | GO:0000448 | cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448) |
| 0.2 | 4.6 | GO:0002931 | response to ischemia(GO:0002931) |
| 0.2 | 0.7 | GO:1900244 | positive regulation of synaptic vesicle endocytosis(GO:1900244) |
| 0.2 | 4.5 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
| 0.2 | 1.2 | GO:1900029 | positive regulation of ruffle assembly(GO:1900029) |
| 0.2 | 0.9 | GO:0006668 | sphinganine-1-phosphate metabolic process(GO:0006668) |
| 0.2 | 2.1 | GO:0014065 | phosphatidylinositol 3-kinase signaling(GO:0014065) |
| 0.2 | 1.4 | GO:0032274 | gonadotropin secretion(GO:0032274) |
| 0.2 | 4.6 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.2 | 3.0 | GO:0070842 | aggresome assembly(GO:0070842) |
| 0.2 | 2.3 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
| 0.2 | 0.9 | GO:0071442 | regulation of histone H3-K14 acetylation(GO:0071440) positive regulation of histone H3-K14 acetylation(GO:0071442) |
| 0.2 | 1.6 | GO:0018243 | protein O-linked glycosylation via threonine(GO:0018243) |
| 0.2 | 2.0 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.2 | 1.6 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
| 0.2 | 0.2 | GO:0090241 | negative regulation of histone H4 acetylation(GO:0090241) |
| 0.2 | 1.1 | GO:0035063 | nuclear speck organization(GO:0035063) |
| 0.2 | 2.0 | GO:0019673 | GDP-mannose metabolic process(GO:0019673) |
| 0.2 | 0.6 | GO:1900042 | positive regulation of interleukin-2 secretion(GO:1900042) |
| 0.2 | 3.4 | GO:0097034 | mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034) |
| 0.2 | 1.1 | GO:0021993 | initiation of neural tube closure(GO:0021993) |
| 0.2 | 0.9 | GO:0071376 | response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376) |
| 0.2 | 2.3 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
| 0.2 | 1.1 | GO:0006851 | mitochondrial calcium ion transport(GO:0006851) |
| 0.2 | 1.7 | GO:0031053 | primary miRNA processing(GO:0031053) |
| 0.2 | 0.8 | GO:0002726 | positive regulation of T cell cytokine production(GO:0002726) |
| 0.2 | 5.6 | GO:0045736 | negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030) |
| 0.2 | 8.5 | GO:0046928 | regulation of neurotransmitter secretion(GO:0046928) |
| 0.2 | 4.5 | GO:0095500 | acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145) |
| 0.2 | 2.3 | GO:0071467 | cellular response to pH(GO:0071467) |
| 0.2 | 1.8 | GO:0042760 | very long-chain fatty acid catabolic process(GO:0042760) |
| 0.2 | 0.8 | GO:0045760 | positive regulation of action potential(GO:0045760) |
| 0.2 | 1.4 | GO:0031642 | negative regulation of myelination(GO:0031642) |
| 0.2 | 2.0 | GO:0090161 | Golgi ribbon formation(GO:0090161) |
| 0.2 | 4.4 | GO:0015804 | neutral amino acid transport(GO:0015804) |
| 0.2 | 1.6 | GO:0007289 | spermatid nucleus differentiation(GO:0007289) |
| 0.2 | 1.6 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
| 0.2 | 1.0 | GO:2000465 | regulation of glycogen (starch) synthase activity(GO:2000465) |
| 0.2 | 1.0 | GO:1904861 | excitatory synapse assembly(GO:1904861) |
| 0.2 | 0.6 | GO:0009838 | abscission(GO:0009838) |
| 0.2 | 0.9 | GO:0090666 | scaRNA localization to Cajal body(GO:0090666) |
| 0.2 | 0.6 | GO:0035526 | retrograde transport, plasma membrane to Golgi(GO:0035526) |
| 0.2 | 3.4 | GO:1900153 | regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153) |
| 0.2 | 4.1 | GO:0007632 | visual behavior(GO:0007632) |
| 0.2 | 0.4 | GO:0070142 | synaptic vesicle budding(GO:0070142) |
| 0.2 | 0.7 | GO:0007342 | fusion of sperm to egg plasma membrane(GO:0007342) |
| 0.2 | 1.5 | GO:0071353 | cellular response to interleukin-4(GO:0071353) |
| 0.2 | 1.3 | GO:0009249 | protein lipoylation(GO:0009249) |
| 0.2 | 3.6 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 0.2 | 2.0 | GO:1900273 | positive regulation of long-term synaptic potentiation(GO:1900273) |
| 0.2 | 0.7 | GO:0006983 | ER overload response(GO:0006983) |
| 0.2 | 0.9 | GO:0051697 | protein delipidation(GO:0051697) |
| 0.2 | 4.3 | GO:0060716 | labyrinthine layer blood vessel development(GO:0060716) |
| 0.2 | 0.9 | GO:0030643 | cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502) |
| 0.2 | 2.7 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
| 0.2 | 3.9 | GO:0006349 | regulation of gene expression by genetic imprinting(GO:0006349) |
| 0.2 | 4.0 | GO:0048488 | synaptic vesicle endocytosis(GO:0048488) |
| 0.2 | 4.5 | GO:0048168 | regulation of neuronal synaptic plasticity(GO:0048168) |
| 0.2 | 2.6 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 0.2 | 0.3 | GO:0002904 | positive regulation of B cell apoptotic process(GO:0002904) |
| 0.2 | 1.6 | GO:0007168 | receptor guanylyl cyclase signaling pathway(GO:0007168) |
| 0.2 | 0.5 | GO:0060278 | preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162) regulation of ovulation(GO:0060278) |
| 0.2 | 3.7 | GO:0070536 | protein K63-linked deubiquitination(GO:0070536) |
| 0.2 | 1.9 | GO:0070995 | NADPH oxidation(GO:0070995) |
| 0.2 | 1.0 | GO:0010747 | positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) |
| 0.2 | 1.3 | GO:0010839 | negative regulation of keratinocyte proliferation(GO:0010839) |
| 0.2 | 2.7 | GO:0030010 | establishment of cell polarity(GO:0030010) |
| 0.2 | 1.1 | GO:0032261 | purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264) |
| 0.2 | 12.2 | GO:1903955 | positive regulation of protein targeting to mitochondrion(GO:1903955) |
| 0.2 | 3.8 | GO:0016578 | histone deubiquitination(GO:0016578) |
| 0.2 | 0.6 | GO:0002484 | antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485) |
| 0.2 | 5.7 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
| 0.2 | 5.0 | GO:0051693 | actin filament capping(GO:0051693) |
| 0.2 | 0.6 | GO:0016480 | negative regulation of transcription from RNA polymerase III promoter(GO:0016480) |
| 0.2 | 0.9 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
| 0.2 | 2.2 | GO:0045898 | regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) |
| 0.2 | 0.8 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
| 0.2 | 1.2 | GO:0015669 | gas transport(GO:0015669) carbon dioxide transport(GO:0015670) |
| 0.2 | 0.5 | GO:0009644 | response to high light intensity(GO:0009644) |
| 0.1 | 0.6 | GO:1990034 | calcium ion export from cell(GO:1990034) |
| 0.1 | 0.3 | GO:0002035 | brain renin-angiotensin system(GO:0002035) |
| 0.1 | 0.7 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.1 | 0.6 | GO:0035509 | negative regulation of myosin-light-chain-phosphatase activity(GO:0035509) |
| 0.1 | 0.3 | GO:0006106 | fumarate metabolic process(GO:0006106) |
| 0.1 | 2.3 | GO:0034389 | lipid particle organization(GO:0034389) |
| 0.1 | 0.1 | GO:0031282 | regulation of guanylate cyclase activity(GO:0031282) |
| 0.1 | 1.3 | GO:0009301 | snRNA transcription(GO:0009301) |
| 0.1 | 1.0 | GO:0051561 | positive regulation of mitochondrial calcium ion concentration(GO:0051561) |
| 0.1 | 0.8 | GO:1900745 | positive regulation of p38MAPK cascade(GO:1900745) |
| 0.1 | 0.4 | GO:0046032 | ADP catabolic process(GO:0046032) |
| 0.1 | 1.8 | GO:0010918 | positive regulation of mitochondrial membrane potential(GO:0010918) |
| 0.1 | 0.4 | GO:0033615 | mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615) |
| 0.1 | 0.8 | GO:0098964 | dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964) |
| 0.1 | 0.7 | GO:1903361 | protein localization to basolateral plasma membrane(GO:1903361) |
| 0.1 | 2.1 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
| 0.1 | 0.4 | GO:0014005 | microglia differentiation(GO:0014004) microglia development(GO:0014005) |
| 0.1 | 0.9 | GO:1900037 | regulation of cellular response to hypoxia(GO:1900037) |
| 0.1 | 0.5 | GO:0030091 | protein repair(GO:0030091) |
| 0.1 | 2.0 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.1 | 1.3 | GO:0043653 | mitochondrial fragmentation involved in apoptotic process(GO:0043653) |
| 0.1 | 1.0 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 0.1 | 3.2 | GO:0045022 | early endosome to late endosome transport(GO:0045022) |
| 0.1 | 2.2 | GO:0032060 | bleb assembly(GO:0032060) |
| 0.1 | 1.6 | GO:0061014 | positive regulation of mRNA catabolic process(GO:0061014) |
| 0.1 | 0.6 | GO:0019086 | late viral transcription(GO:0019086) |
| 0.1 | 0.6 | GO:0048875 | surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875) |
| 0.1 | 0.7 | GO:0045040 | protein import into mitochondrial outer membrane(GO:0045040) |
| 0.1 | 0.5 | GO:2000310 | regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310) |
| 0.1 | 0.7 | GO:0060046 | regulation of acrosome reaction(GO:0060046) |
| 0.1 | 5.1 | GO:0032091 | negative regulation of protein binding(GO:0032091) |
| 0.1 | 3.2 | GO:0010614 | negative regulation of cardiac muscle hypertrophy(GO:0010614) |
| 0.1 | 1.8 | GO:0070207 | protein homotrimerization(GO:0070207) |
| 0.1 | 1.1 | GO:0048266 | behavioral response to pain(GO:0048266) |
| 0.1 | 0.3 | GO:0019074 | viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) |
| 0.1 | 0.8 | GO:1902746 | regulation of lens fiber cell differentiation(GO:1902746) |
| 0.1 | 5.2 | GO:0061178 | regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178) |
| 0.1 | 0.5 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.1 | 0.3 | GO:0036353 | histone H2A-K119 monoubiquitination(GO:0036353) |
| 0.1 | 2.2 | GO:0033003 | regulation of mast cell activation(GO:0033003) |
| 0.1 | 0.5 | GO:0042891 | antibiotic transport(GO:0042891) |
| 0.1 | 2.9 | GO:0055013 | cardiac muscle cell development(GO:0055013) |
| 0.1 | 1.8 | GO:0014067 | negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067) |
| 0.1 | 0.9 | GO:0043552 | positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552) |
| 0.1 | 3.4 | GO:0045599 | negative regulation of fat cell differentiation(GO:0045599) |
| 0.1 | 2.9 | GO:0006694 | steroid biosynthetic process(GO:0006694) |
| 0.1 | 0.9 | GO:0035814 | regulation of renal sodium excretion(GO:0035813) negative regulation of renal sodium excretion(GO:0035814) |
| 0.1 | 1.3 | GO:0046856 | phosphatidylinositol dephosphorylation(GO:0046856) |
| 0.1 | 7.5 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
| 0.1 | 1.4 | GO:2000785 | regulation of autophagosome assembly(GO:2000785) |
| 0.1 | 0.9 | GO:0050774 | negative regulation of dendrite morphogenesis(GO:0050774) |
| 0.1 | 0.2 | GO:2001023 | regulation of response to drug(GO:2001023) |
| 0.1 | 0.5 | GO:1903553 | positive regulation of extracellular exosome assembly(GO:1903553) |
| 0.1 | 0.7 | GO:0006283 | transcription-coupled nucleotide-excision repair(GO:0006283) |
| 0.1 | 0.7 | GO:0032790 | ribosome disassembly(GO:0032790) |
| 0.1 | 0.3 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
| 0.1 | 6.1 | GO:0051865 | protein autoubiquitination(GO:0051865) |
| 0.1 | 1.1 | GO:0006919 | activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919) |
| 0.1 | 1.0 | GO:2000171 | negative regulation of dendrite development(GO:2000171) |
| 0.1 | 0.2 | GO:0051026 | chiasma assembly(GO:0051026) |
| 0.1 | 1.2 | GO:0060088 | auditory receptor cell stereocilium organization(GO:0060088) |
| 0.1 | 2.0 | GO:0072583 | clathrin-mediated endocytosis(GO:0072583) |
| 0.1 | 0.5 | GO:0006689 | ganglioside catabolic process(GO:0006689) |
| 0.1 | 0.8 | GO:0060136 | embryonic process involved in female pregnancy(GO:0060136) |
| 0.1 | 0.7 | GO:0090267 | positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) |
| 0.1 | 2.5 | GO:0000266 | mitochondrial fission(GO:0000266) |
| 0.1 | 1.0 | GO:1904294 | positive regulation of ERAD pathway(GO:1904294) |
| 0.1 | 2.8 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
| 0.1 | 1.2 | GO:0021869 | forebrain ventricular zone progenitor cell division(GO:0021869) |
| 0.1 | 2.7 | GO:0000045 | autophagosome assembly(GO:0000045) |
| 0.1 | 1.1 | GO:1902236 | negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236) |
| 0.1 | 0.4 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
| 0.1 | 1.4 | GO:0070200 | establishment of protein localization to telomere(GO:0070200) |
| 0.1 | 0.4 | GO:0051642 | centrosome localization(GO:0051642) |
| 0.1 | 0.3 | GO:0044208 | 'de novo' AMP biosynthetic process(GO:0044208) |
| 0.1 | 0.6 | GO:0000186 | activation of MAPKK activity(GO:0000186) |
| 0.1 | 2.7 | GO:0019228 | neuronal action potential(GO:0019228) |
| 0.1 | 1.7 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 0.1 | 0.6 | GO:0090043 | regulation of tubulin deacetylation(GO:0090043) |
| 0.1 | 0.8 | GO:0009191 | ribonucleoside diphosphate catabolic process(GO:0009191) |
| 0.1 | 2.2 | GO:0009299 | mRNA transcription(GO:0009299) |
| 0.1 | 1.0 | GO:0043982 | histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982) histone H4-K16 acetylation(GO:0043984) |
| 0.1 | 2.9 | GO:0018279 | peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279) |
| 0.1 | 0.6 | GO:0050862 | positive regulation of T cell receptor signaling pathway(GO:0050862) |
| 0.1 | 0.5 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
| 0.1 | 0.9 | GO:1902916 | positive regulation of protein polyubiquitination(GO:1902916) |
| 0.1 | 1.0 | GO:0031507 | heterochromatin assembly(GO:0031507) |
| 0.1 | 1.4 | GO:0019884 | antigen processing and presentation of exogenous antigen(GO:0019884) |
| 0.1 | 0.4 | GO:0007603 | phototransduction, visible light(GO:0007603) |
| 0.1 | 3.1 | GO:0021680 | cerebellar Purkinje cell layer development(GO:0021680) |
| 0.1 | 0.5 | GO:0033034 | positive regulation of neutrophil apoptotic process(GO:0033031) positive regulation of myeloid cell apoptotic process(GO:0033034) |
| 0.1 | 1.0 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) |
| 0.1 | 1.6 | GO:0000305 | response to oxygen radical(GO:0000305) |
| 0.1 | 0.5 | GO:0001731 | formation of translation preinitiation complex(GO:0001731) |
| 0.1 | 0.5 | GO:2001197 | basement membrane assembly(GO:0070831) regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197) |
| 0.1 | 4.1 | GO:0022900 | electron transport chain(GO:0022900) |
| 0.1 | 4.2 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
| 0.1 | 0.1 | GO:0006933 | negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933) |
| 0.1 | 0.7 | GO:0006098 | pentose-phosphate shunt(GO:0006098) |
| 0.1 | 9.7 | GO:0008654 | phospholipid biosynthetic process(GO:0008654) |
| 0.1 | 0.5 | GO:0045176 | apical protein localization(GO:0045176) |
| 0.1 | 0.3 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
| 0.1 | 1.3 | GO:0007189 | adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189) |
| 0.1 | 0.3 | GO:0006244 | pyrimidine nucleotide catabolic process(GO:0006244) pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211) pyrimidine deoxyribonucleotide catabolic process(GO:0009223) |
| 0.1 | 1.4 | GO:0034063 | stress granule assembly(GO:0034063) |
| 0.1 | 0.5 | GO:0042790 | transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790) |
| 0.1 | 1.1 | GO:0097352 | autophagosome maturation(GO:0097352) |
| 0.1 | 2.0 | GO:0035065 | regulation of histone acetylation(GO:0035065) |
| 0.1 | 0.9 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
| 0.1 | 3.1 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.1 | 0.9 | GO:0002021 | response to dietary excess(GO:0002021) |
| 0.1 | 0.3 | GO:1904995 | negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995) |
| 0.1 | 1.7 | GO:0009408 | response to heat(GO:0009408) |
| 0.1 | 0.3 | GO:0014850 | response to muscle activity(GO:0014850) |
| 0.1 | 1.3 | GO:0050850 | positive regulation of calcium-mediated signaling(GO:0050850) |
| 0.1 | 0.1 | GO:1904751 | positive regulation of protein localization to nucleolus(GO:1904751) |
| 0.1 | 0.9 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 0.1 | 1.8 | GO:0008089 | anterograde axonal transport(GO:0008089) |
| 0.1 | 0.2 | GO:0042823 | pyridoxal phosphate biosynthetic process(GO:0042823) |
| 0.1 | 0.5 | GO:0080009 | mRNA methylation(GO:0080009) |
| 0.1 | 0.7 | GO:0043457 | regulation of cellular respiration(GO:0043457) |
| 0.1 | 1.4 | GO:0097031 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 0.1 | 1.4 | GO:0015991 | energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662) |
| 0.1 | 1.8 | GO:0045921 | positive regulation of exocytosis(GO:0045921) |
| 0.1 | 0.7 | GO:0006878 | cellular copper ion homeostasis(GO:0006878) |
| 0.1 | 2.1 | GO:0030433 | ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) |
| 0.1 | 2.3 | GO:0006487 | protein N-linked glycosylation(GO:0006487) |
| 0.1 | 0.2 | GO:0036481 | intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036481) |
| 0.1 | 0.6 | GO:0035988 | chondrocyte proliferation(GO:0035988) |
| 0.1 | 0.7 | GO:0001964 | startle response(GO:0001964) |
| 0.1 | 0.6 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.1 | 0.7 | GO:0046498 | S-adenosylhomocysteine metabolic process(GO:0046498) |
| 0.1 | 0.2 | GO:0071596 | ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596) |
| 0.0 | 0.7 | GO:0022038 | corpus callosum development(GO:0022038) |
| 0.0 | 0.2 | GO:0002098 | tRNA wobble uridine modification(GO:0002098) |
| 0.0 | 0.7 | GO:1902254 | negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254) |
| 0.0 | 0.7 | GO:0000038 | very long-chain fatty acid metabolic process(GO:0000038) |
| 0.0 | 1.2 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
| 0.0 | 0.2 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
| 0.0 | 0.1 | GO:0002551 | mast cell chemotaxis(GO:0002551) positive regulation of vascular wound healing(GO:0035470) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531) |
| 0.0 | 0.3 | GO:0061001 | regulation of dendritic spine morphogenesis(GO:0061001) |
| 0.0 | 0.5 | GO:0051084 | 'de novo' posttranslational protein folding(GO:0051084) chaperone mediated protein folding requiring cofactor(GO:0051085) |
| 0.0 | 0.7 | GO:0006613 | cotranslational protein targeting to membrane(GO:0006613) |
| 0.0 | 1.7 | GO:0006836 | neurotransmitter transport(GO:0006836) |
| 0.0 | 2.3 | GO:0006887 | exocytosis(GO:0006887) |
| 0.0 | 0.1 | GO:0006751 | glutathione catabolic process(GO:0006751) |
| 0.0 | 1.1 | GO:0006829 | zinc II ion transport(GO:0006829) |
| 0.0 | 0.2 | GO:0010758 | regulation of macrophage chemotaxis(GO:0010758) |
| 0.0 | 0.1 | GO:0046900 | tetrahydrofolylpolyglutamate metabolic process(GO:0046900) |
| 0.0 | 0.9 | GO:0045761 | regulation of adenylate cyclase activity(GO:0045761) |
| 0.0 | 0.2 | GO:0001955 | blood vessel maturation(GO:0001955) |
| 0.0 | 0.6 | GO:0022617 | extracellular matrix disassembly(GO:0022617) |
| 0.0 | 0.1 | GO:0030851 | granulocyte differentiation(GO:0030851) |
| 0.0 | 0.5 | GO:0045807 | positive regulation of endocytosis(GO:0045807) |
| 0.0 | 1.1 | GO:0006612 | protein targeting to membrane(GO:0006612) |
| 0.0 | 0.1 | GO:0032415 | regulation of sodium:proton antiporter activity(GO:0032415) positive regulation of sodium:proton antiporter activity(GO:0032417) |
| 0.0 | 0.9 | GO:0071526 | semaphorin-plexin signaling pathway(GO:0071526) |
| 0.0 | 0.1 | GO:0002014 | vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014) |
| 0.0 | 0.5 | GO:0071514 | genetic imprinting(GO:0071514) |
| 0.0 | 0.5 | GO:0008543 | fibroblast growth factor receptor signaling pathway(GO:0008543) |
| 0.0 | 0.3 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
| 0.0 | 0.1 | GO:0060644 | mammary gland epithelial cell differentiation(GO:0060644) |
| 0.0 | 1.1 | GO:0008610 | lipid biosynthetic process(GO:0008610) |
| 0.0 | 0.7 | GO:0015807 | L-amino acid transport(GO:0015807) |
| 0.0 | 0.3 | GO:0033211 | adiponectin-activated signaling pathway(GO:0033211) |
| 0.0 | 0.7 | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146) |
| 0.0 | 1.0 | GO:0070527 | platelet aggregation(GO:0070527) |
| 0.0 | 0.3 | GO:0006910 | phagocytosis, recognition(GO:0006910) |
| 0.0 | 0.5 | GO:0072384 | organelle transport along microtubule(GO:0072384) |
| 0.0 | 0.3 | GO:0032897 | negative regulation of viral transcription(GO:0032897) |
| 0.0 | 0.1 | GO:0000727 | double-strand break repair via break-induced replication(GO:0000727) |
| 0.0 | 0.3 | GO:0046597 | negative regulation of viral entry into host cell(GO:0046597) |
| 0.0 | 0.8 | GO:0015992 | proton transport(GO:0015992) |
| 0.0 | 0.8 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
| 0.0 | 0.2 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
| 0.0 | 1.1 | GO:0007030 | Golgi organization(GO:0007030) |
| 0.0 | 0.1 | GO:0036296 | lysosomal lumen acidification(GO:0007042) cellular response to increased oxygen levels(GO:0036295) response to increased oxygen levels(GO:0036296) |
| 0.0 | 0.5 | GO:0050775 | positive regulation of dendrite morphogenesis(GO:0050775) |
| 0.0 | 0.2 | GO:0098930 | axonal transport(GO:0098930) |
| 0.0 | 0.0 | GO:0009794 | regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448) |
| 0.0 | 0.1 | GO:0030950 | establishment or maintenance of actin cytoskeleton polarity(GO:0030950) |
| 0.0 | 0.4 | GO:0032418 | lysosome localization(GO:0032418) |
| 0.0 | 0.1 | GO:0045063 | T-helper 1 cell differentiation(GO:0045063) |
| 0.0 | 0.4 | GO:0046513 | ceramide biosynthetic process(GO:0046513) |
| 0.0 | 0.2 | GO:0070897 | DNA-templated transcriptional preinitiation complex assembly(GO:0070897) |
| 0.0 | 0.7 | GO:0007416 | synapse assembly(GO:0007416) |
| 0.0 | 0.1 | GO:0016139 | glycoside catabolic process(GO:0016139) |
| 0.0 | 0.2 | GO:0009048 | dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048) |
| 0.0 | 0.3 | GO:1902042 | negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042) |
| 0.0 | 0.0 | GO:0030224 | monocyte differentiation(GO:0030224) |
| 0.0 | 0.2 | GO:0006446 | regulation of translational initiation(GO:0006446) |
| 0.0 | 0.1 | GO:2000580 | regulation of microtubule motor activity(GO:2000574) positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582) |
| 0.0 | 0.2 | GO:0035024 | negative regulation of Rho protein signal transduction(GO:0035024) |
| 0.0 | 0.2 | GO:0046677 | response to antibiotic(GO:0046677) |
| 0.0 | 0.5 | GO:0006626 | protein targeting to mitochondrion(GO:0006626) |
| 0.0 | 0.9 | GO:0007623 | circadian rhythm(GO:0007623) |
| 0.0 | 0.1 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 0.0 | 0.8 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
| 0.0 | 0.1 | GO:0006622 | protein targeting to lysosome(GO:0006622) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.3 | 36.5 | GO:0043196 | varicosity(GO:0043196) |
| 1.9 | 65.6 | GO:0051233 | spindle midzone(GO:0051233) |
| 1.8 | 10.6 | GO:0008091 | spectrin(GO:0008091) |
| 1.7 | 13.7 | GO:0097433 | dense body(GO:0097433) |
| 1.6 | 4.9 | GO:0098855 | HCN channel complex(GO:0098855) |
| 1.4 | 4.3 | GO:0033596 | TSC1-TSC2 complex(GO:0033596) |
| 1.4 | 5.6 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
| 1.1 | 5.6 | GO:1903440 | calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440) |
| 1.0 | 11.3 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 1.0 | 15.0 | GO:0043083 | synaptic cleft(GO:0043083) |
| 1.0 | 4.8 | GO:0030314 | junctional membrane complex(GO:0030314) |
| 0.9 | 3.5 | GO:1990111 | spermatoproteasome complex(GO:1990111) |
| 0.8 | 8.1 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.8 | 11.4 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 0.7 | 6.2 | GO:0044327 | dendritic spine head(GO:0044327) |
| 0.7 | 5.3 | GO:0033391 | chromatoid body(GO:0033391) |
| 0.6 | 2.5 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) |
| 0.6 | 4.9 | GO:0005787 | signal peptidase complex(GO:0005787) |
| 0.6 | 1.8 | GO:0034657 | GID complex(GO:0034657) |
| 0.6 | 7.1 | GO:0044294 | dendritic growth cone(GO:0044294) |
| 0.6 | 7.6 | GO:1990635 | proximal dendrite(GO:1990635) |
| 0.6 | 4.6 | GO:0033269 | internode region of axon(GO:0033269) |
| 0.6 | 1.7 | GO:1903095 | microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095) |
| 0.6 | 6.6 | GO:0020005 | symbiont-containing vacuole membrane(GO:0020005) |
| 0.5 | 21.0 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.5 | 4.6 | GO:0031254 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
| 0.5 | 4.1 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.5 | 2.0 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 0.5 | 1.5 | GO:0043540 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540) |
| 0.5 | 4.3 | GO:0036157 | outer dynein arm(GO:0036157) |
| 0.5 | 1.8 | GO:1903349 | omegasome membrane(GO:1903349) |
| 0.5 | 6.9 | GO:0032279 | asymmetric synapse(GO:0032279) |
| 0.4 | 1.3 | GO:0005940 | septin ring(GO:0005940) |
| 0.4 | 2.2 | GO:0097227 | sperm annulus(GO:0097227) |
| 0.4 | 3.0 | GO:0070695 | FHF complex(GO:0070695) |
| 0.4 | 1.3 | GO:0009328 | phenylalanine-tRNA ligase complex(GO:0009328) |
| 0.4 | 1.3 | GO:0045160 | myosin I complex(GO:0045160) |
| 0.4 | 3.7 | GO:0061617 | MICOS complex(GO:0061617) |
| 0.4 | 1.6 | GO:0044301 | climbing fiber(GO:0044301) parallel fiber(GO:1990032) |
| 0.4 | 4.4 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.4 | 2.0 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.4 | 3.1 | GO:0030130 | clathrin coat of trans-Golgi network vesicle(GO:0030130) |
| 0.4 | 3.1 | GO:0001520 | outer dense fiber(GO:0001520) |
| 0.4 | 1.5 | GO:0001651 | dense fibrillar component(GO:0001651) |
| 0.4 | 1.8 | GO:0032389 | MutLalpha complex(GO:0032389) |
| 0.4 | 3.2 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.3 | 24.3 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.3 | 2.4 | GO:0044352 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 0.3 | 0.7 | GO:0061689 | tricellular tight junction(GO:0061689) |
| 0.3 | 1.7 | GO:0070876 | SOSS complex(GO:0070876) |
| 0.3 | 4.3 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.3 | 0.9 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
| 0.3 | 9.3 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.3 | 1.2 | GO:0002141 | stereocilia ankle link(GO:0002141) |
| 0.3 | 1.8 | GO:0071439 | clathrin complex(GO:0071439) |
| 0.3 | 5.0 | GO:0000124 | SAGA complex(GO:0000124) |
| 0.3 | 4.1 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
| 0.3 | 0.9 | GO:0097233 | lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233) |
| 0.3 | 1.6 | GO:0017059 | serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211) |
| 0.3 | 4.0 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.3 | 2.1 | GO:0005851 | eukaryotic translation initiation factor 2B complex(GO:0005851) |
| 0.3 | 2.6 | GO:0032426 | stereocilium tip(GO:0032426) |
| 0.3 | 19.9 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.3 | 1.3 | GO:0000120 | RNA polymerase I transcription factor complex(GO:0000120) |
| 0.3 | 4.8 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.2 | 0.7 | GO:0034667 | integrin alpha3-beta1 complex(GO:0034667) |
| 0.2 | 5.7 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.2 | 0.9 | GO:0031983 | vesicle lumen(GO:0031983) |
| 0.2 | 2.1 | GO:0042587 | glycogen granule(GO:0042587) |
| 0.2 | 1.1 | GO:0097208 | alveolar lamellar body(GO:0097208) |
| 0.2 | 0.9 | GO:0071797 | LUBAC complex(GO:0071797) |
| 0.2 | 25.0 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.2 | 28.6 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 0.2 | 1.9 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
| 0.2 | 1.2 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 0.2 | 24.5 | GO:0008021 | synaptic vesicle(GO:0008021) |
| 0.2 | 5.5 | GO:0030137 | COPI-coated vesicle(GO:0030137) |
| 0.2 | 3.2 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 0.2 | 2.2 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
| 0.2 | 2.9 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.2 | 6.4 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.2 | 1.0 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
| 0.2 | 1.1 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
| 0.2 | 0.8 | GO:0019897 | extrinsic component of plasma membrane(GO:0019897) |
| 0.2 | 1.6 | GO:0044232 | organelle membrane contact site(GO:0044232) |
| 0.2 | 2.0 | GO:0032590 | dendrite membrane(GO:0032590) |
| 0.2 | 1.2 | GO:0005638 | lamin filament(GO:0005638) |
| 0.2 | 6.0 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 0.2 | 3.4 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.2 | 0.7 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
| 0.2 | 1.2 | GO:0036195 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
| 0.2 | 0.7 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
| 0.2 | 44.5 | GO:0014069 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
| 0.2 | 2.1 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.2 | 0.8 | GO:0030891 | VCB complex(GO:0030891) |
| 0.2 | 1.4 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
| 0.2 | 1.2 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.2 | 2.9 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.1 | 1.2 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.1 | 1.0 | GO:0097413 | Lewy body(GO:0097413) |
| 0.1 | 2.7 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 0.1 | 0.6 | GO:0045098 | type III intermediate filament(GO:0045098) |
| 0.1 | 0.4 | GO:0033186 | CAF-1 complex(GO:0033186) |
| 0.1 | 3.3 | GO:0031305 | integral component of mitochondrial inner membrane(GO:0031305) |
| 0.1 | 6.3 | GO:0005776 | autophagosome(GO:0005776) |
| 0.1 | 2.1 | GO:0000145 | exocyst(GO:0000145) |
| 0.1 | 2.5 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
| 0.1 | 2.9 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.1 | 1.5 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 0.1 | 0.4 | GO:0042720 | mitochondrial inner membrane peptidase complex(GO:0042720) |
| 0.1 | 3.3 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.1 | 6.1 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.1 | 0.6 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 0.1 | 5.2 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.1 | 0.7 | GO:0031314 | extrinsic component of mitochondrial inner membrane(GO:0031314) |
| 0.1 | 16.1 | GO:0045211 | postsynaptic membrane(GO:0045211) |
| 0.1 | 1.1 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.1 | 2.5 | GO:0005771 | multivesicular body(GO:0005771) |
| 0.1 | 0.5 | GO:1990130 | Iml1 complex(GO:1990130) |
| 0.1 | 2.0 | GO:0000780 | condensed nuclear chromosome, centromeric region(GO:0000780) |
| 0.1 | 0.5 | GO:0036396 | MIS complex(GO:0036396) mRNA editing complex(GO:0045293) |
| 0.1 | 2.4 | GO:0045259 | proton-transporting ATP synthase complex(GO:0045259) |
| 0.1 | 0.8 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
| 0.1 | 1.0 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 0.1 | 16.0 | GO:0098852 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
| 0.1 | 0.7 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
| 0.1 | 2.1 | GO:0030904 | retromer complex(GO:0030904) |
| 0.1 | 5.8 | GO:0043204 | perikaryon(GO:0043204) |
| 0.1 | 9.3 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.1 | 0.3 | GO:0044292 | dendrite terminus(GO:0044292) kinociliary basal body(GO:1902636) |
| 0.1 | 0.8 | GO:0034709 | methylosome(GO:0034709) |
| 0.1 | 1.8 | GO:0005921 | gap junction(GO:0005921) |
| 0.1 | 1.5 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.1 | 3.1 | GO:0032587 | ruffle membrane(GO:0032587) |
| 0.1 | 3.1 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.1 | 6.2 | GO:0009986 | cell surface(GO:0009986) |
| 0.1 | 4.0 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
| 0.1 | 0.9 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
| 0.1 | 0.5 | GO:0042582 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
| 0.1 | 1.1 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.1 | 5.6 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.1 | 3.2 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.1 | 0.6 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.1 | 0.7 | GO:0042612 | MHC class I protein complex(GO:0042612) |
| 0.1 | 0.6 | GO:0016272 | prefoldin complex(GO:0016272) |
| 0.1 | 2.2 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
| 0.1 | 2.2 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.1 | 1.7 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.1 | 1.2 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.1 | 0.2 | GO:0001674 | female germ cell nucleus(GO:0001674) |
| 0.1 | 0.3 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
| 0.1 | 0.5 | GO:0031083 | BLOC-1 complex(GO:0031083) |
| 0.1 | 0.4 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.1 | 12.0 | GO:0000139 | Golgi membrane(GO:0000139) |
| 0.1 | 0.4 | GO:0071012 | catalytic step 1 spliceosome(GO:0071012) |
| 0.1 | 1.8 | GO:0001726 | ruffle(GO:0001726) |
| 0.0 | 1.5 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.0 | 0.3 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 0.0 | 0.2 | GO:0097361 | CIA complex(GO:0097361) |
| 0.0 | 0.7 | GO:0030134 | ER to Golgi transport vesicle(GO:0030134) |
| 0.0 | 0.9 | GO:0005685 | U1 snRNP(GO:0005685) |
| 0.0 | 0.4 | GO:0016589 | NURF complex(GO:0016589) |
| 0.0 | 0.5 | GO:0045180 | basal cortex(GO:0045180) |
| 0.0 | 3.0 | GO:0044306 | neuron projection terminus(GO:0044306) |
| 0.0 | 0.3 | GO:0005956 | protein kinase CK2 complex(GO:0005956) |
| 0.0 | 1.1 | GO:0030175 | filopodium(GO:0030175) |
| 0.0 | 1.4 | GO:0071339 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
| 0.0 | 1.5 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.0 | 0.4 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.0 | 11.9 | GO:0043025 | neuronal cell body(GO:0043025) |
| 0.0 | 1.6 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.0 | 0.3 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.0 | 0.6 | GO:0045335 | phagocytic vesicle(GO:0045335) |
| 0.0 | 111.0 | GO:0016021 | integral component of membrane(GO:0016021) |
| 0.0 | 0.1 | GO:0016461 | unconventional myosin complex(GO:0016461) |
| 0.0 | 0.3 | GO:0000439 | core TFIIH complex(GO:0000439) |
| 0.0 | 0.1 | GO:0034361 | very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385) |
| 0.0 | 0.2 | GO:0034464 | BBSome(GO:0034464) |
| 0.0 | 0.4 | GO:0030008 | TRAPP complex(GO:0030008) |
| 0.0 | 0.2 | GO:0098793 | presynapse(GO:0098793) |
| 0.0 | 1.0 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 0.5 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
| 0.0 | 1.4 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 0.2 | GO:0090576 | RNA polymerase III transcription factor complex(GO:0090576) |
| 0.0 | 0.2 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
| 0.0 | 0.5 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 2.2 | GO:0005764 | lytic vacuole(GO:0000323) lysosome(GO:0005764) |
| 0.0 | 0.1 | GO:0033503 | HULC complex(GO:0033503) |
| 0.0 | 0.1 | GO:0045277 | mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277) |
| 0.0 | 0.1 | GO:0035253 | ciliary rootlet(GO:0035253) |
| 0.0 | 0.5 | GO:0005923 | bicellular tight junction(GO:0005923) |
| 0.0 | 0.3 | GO:0008180 | COP9 signalosome(GO:0008180) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.3 | 33.2 | GO:0031749 | D2 dopamine receptor binding(GO:0031749) |
| 3.1 | 81.8 | GO:0043274 | phospholipase binding(GO:0043274) |
| 2.8 | 8.5 | GO:0004936 | alpha-adrenergic receptor activity(GO:0004936) epinephrine binding(GO:0051379) |
| 1.9 | 11.4 | GO:0022851 | GABA-gated chloride ion channel activity(GO:0022851) |
| 1.8 | 9.1 | GO:0034235 | GPI anchor binding(GO:0034235) |
| 1.8 | 5.3 | GO:0022865 | transmembrane electron transfer carrier(GO:0022865) |
| 1.7 | 5.2 | GO:0004574 | oligo-1,6-glucosidase activity(GO:0004574) |
| 1.7 | 6.7 | GO:0061505 | DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505) |
| 1.6 | 6.4 | GO:0004096 | catalase activity(GO:0004096) |
| 1.5 | 10.7 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
| 1.4 | 4.3 | GO:0004993 | G-protein coupled serotonin receptor activity(GO:0004993) |
| 1.4 | 4.2 | GO:0046624 | sphingolipid transporter activity(GO:0046624) |
| 1.4 | 7.0 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
| 1.3 | 6.6 | GO:0048248 | CXCR3 chemokine receptor binding(GO:0048248) |
| 1.3 | 25.0 | GO:0034483 | heparan sulfate sulfotransferase activity(GO:0034483) |
| 1.3 | 6.4 | GO:0033691 | sialic acid binding(GO:0033691) |
| 1.3 | 5.1 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 1.2 | 4.9 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
| 1.2 | 15.7 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 1.1 | 3.4 | GO:0008332 | low voltage-gated calcium channel activity(GO:0008332) |
| 1.1 | 4.5 | GO:0019962 | interferon receptor activity(GO:0004904) type I interferon receptor activity(GO:0004905) type I interferon binding(GO:0019962) |
| 1.1 | 5.6 | GO:0097643 | amylin receptor activity(GO:0097643) |
| 1.1 | 4.3 | GO:1902282 | voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282) |
| 1.0 | 8.1 | GO:0086007 | voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007) |
| 1.0 | 3.8 | GO:0001602 | pancreatic polypeptide receptor activity(GO:0001602) |
| 0.9 | 2.8 | GO:0003846 | 2-acylglycerol O-acyltransferase activity(GO:0003846) |
| 0.9 | 2.8 | GO:0004510 | tryptophan 5-monooxygenase activity(GO:0004510) |
| 0.9 | 4.7 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
| 0.9 | 2.8 | GO:0004473 | malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) |
| 0.9 | 2.6 | GO:0031826 | type 2A serotonin receptor binding(GO:0031826) |
| 0.8 | 3.3 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
| 0.8 | 3.3 | GO:0004667 | prostaglandin-D synthase activity(GO:0004667) |
| 0.8 | 3.3 | GO:0016909 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
| 0.8 | 4.6 | GO:0015018 | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018) |
| 0.8 | 6.0 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.8 | 3.0 | GO:0008967 | phosphoglycolate phosphatase activity(GO:0008967) |
| 0.7 | 6.7 | GO:0003873 | 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) |
| 0.7 | 2.9 | GO:0047238 | glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238) |
| 0.7 | 2.9 | GO:0061628 | H3K27me3 modified histone binding(GO:0061628) |
| 0.7 | 3.4 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
| 0.7 | 8.1 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.7 | 3.4 | GO:0003945 | N-acetyllactosamine synthase activity(GO:0003945) |
| 0.7 | 2.7 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
| 0.7 | 2.6 | GO:0001537 | N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537) |
| 0.6 | 5.1 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
| 0.6 | 2.4 | GO:0004735 | pyrroline-5-carboxylate reductase activity(GO:0004735) |
| 0.6 | 2.3 | GO:0035514 | DNA demethylase activity(GO:0035514) |
| 0.6 | 20.9 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.5 | 1.6 | GO:0004758 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
| 0.5 | 14.0 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.5 | 2.7 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.5 | 3.1 | GO:0008294 | calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294) |
| 0.5 | 4.2 | GO:0047631 | ADP-ribose diphosphatase activity(GO:0047631) |
| 0.5 | 2.1 | GO:0004315 | 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) |
| 0.5 | 4.5 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.5 | 4.5 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
| 0.5 | 10.5 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
| 0.5 | 1.5 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
| 0.5 | 1.5 | GO:0042134 | rRNA primary transcript binding(GO:0042134) |
| 0.5 | 3.9 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.5 | 2.9 | GO:0003854 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) |
| 0.5 | 17.6 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
| 0.5 | 0.9 | GO:0043125 | ErbB-3 class receptor binding(GO:0043125) |
| 0.5 | 3.7 | GO:0015193 | L-proline transmembrane transporter activity(GO:0015193) |
| 0.5 | 8.7 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
| 0.5 | 2.7 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
| 0.5 | 1.8 | GO:0032138 | single base insertion or deletion binding(GO:0032138) |
| 0.4 | 2.2 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
| 0.4 | 1.8 | GO:0004074 | biliverdin reductase activity(GO:0004074) |
| 0.4 | 1.8 | GO:0004427 | inorganic diphosphatase activity(GO:0004427) |
| 0.4 | 2.2 | GO:0004028 | 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) |
| 0.4 | 4.7 | GO:0008430 | selenium binding(GO:0008430) |
| 0.4 | 2.1 | GO:0008427 | calcium-dependent protein kinase inhibitor activity(GO:0008427) |
| 0.4 | 1.3 | GO:0004828 | serine-tRNA ligase activity(GO:0004828) |
| 0.4 | 2.9 | GO:0015217 | ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217) |
| 0.4 | 1.7 | GO:0035243 | protein-arginine omega-N symmetric methyltransferase activity(GO:0035243) |
| 0.4 | 12.6 | GO:0017046 | peptide hormone binding(GO:0017046) |
| 0.4 | 1.6 | GO:0004706 | JUN kinase kinase kinase activity(GO:0004706) |
| 0.4 | 1.1 | GO:0019153 | protein-disulfide reductase (glutathione) activity(GO:0019153) |
| 0.4 | 1.5 | GO:0005131 | growth hormone receptor binding(GO:0005131) |
| 0.4 | 1.5 | GO:1902379 | chemoattractant activity involved in axon guidance(GO:1902379) |
| 0.4 | 5.1 | GO:0008484 | sulfuric ester hydrolase activity(GO:0008484) |
| 0.3 | 2.1 | GO:0004311 | farnesyltranstransferase activity(GO:0004311) |
| 0.3 | 1.4 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
| 0.3 | 1.0 | GO:0004875 | complement receptor activity(GO:0004875) |
| 0.3 | 1.0 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
| 0.3 | 1.7 | GO:0004525 | ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) |
| 0.3 | 2.3 | GO:0008499 | UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499) |
| 0.3 | 1.0 | GO:0003796 | lysozyme activity(GO:0003796) |
| 0.3 | 1.0 | GO:0019120 | hydrolase activity, acting on acid halide bonds(GO:0016824) hydrolase activity, acting on acid halide bonds, in C-halide compounds(GO:0019120) alkylhalidase activity(GO:0047651) |
| 0.3 | 6.7 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
| 0.3 | 7.7 | GO:0030506 | ankyrin binding(GO:0030506) |
| 0.3 | 1.6 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
| 0.3 | 6.3 | GO:0070300 | phosphatidic acid binding(GO:0070300) |
| 0.3 | 3.5 | GO:0009922 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.3 | 0.9 | GO:0000033 | alpha-1,3-mannosyltransferase activity(GO:0000033) |
| 0.3 | 1.9 | GO:0042923 | neuropeptide binding(GO:0042923) |
| 0.3 | 3.1 | GO:0035014 | phosphatidylinositol 3-kinase regulator activity(GO:0035014) |
| 0.3 | 2.1 | GO:0015091 | ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510) |
| 0.3 | 3.6 | GO:0015101 | organic cation transmembrane transporter activity(GO:0015101) |
| 0.3 | 5.0 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.3 | 0.9 | GO:0071723 | lipopeptide binding(GO:0071723) |
| 0.3 | 3.5 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.3 | 4.1 | GO:1900750 | glutathione binding(GO:0043295) oligopeptide binding(GO:1900750) |
| 0.3 | 2.0 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.3 | 1.4 | GO:0043812 | phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) |
| 0.3 | 1.4 | GO:0071617 | lysophospholipid acyltransferase activity(GO:0071617) |
| 0.3 | 3.8 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.3 | 1.9 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
| 0.3 | 3.5 | GO:0030346 | protein phosphatase 2B binding(GO:0030346) |
| 0.3 | 0.8 | GO:0034190 | apolipoprotein receptor binding(GO:0034190) |
| 0.3 | 1.6 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
| 0.3 | 3.2 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.3 | 1.1 | GO:0050544 | arachidonic acid binding(GO:0050544) |
| 0.3 | 3.1 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
| 0.3 | 0.8 | GO:0015232 | heme transporter activity(GO:0015232) |
| 0.3 | 1.3 | GO:0004826 | phenylalanine-tRNA ligase activity(GO:0004826) |
| 0.3 | 4.8 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.3 | 3.5 | GO:0045505 | dynein intermediate chain binding(GO:0045505) |
| 0.3 | 1.5 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
| 0.2 | 1.7 | GO:0015288 | porin activity(GO:0015288) |
| 0.2 | 3.4 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.2 | 2.6 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 0.2 | 0.9 | GO:0005021 | vascular endothelial growth factor-activated receptor activity(GO:0005021) |
| 0.2 | 1.4 | GO:0048039 | ubiquinone binding(GO:0048039) |
| 0.2 | 0.7 | GO:0030368 | interleukin-17 receptor activity(GO:0030368) |
| 0.2 | 4.4 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.2 | 1.4 | GO:0004791 | thioredoxin-disulfide reductase activity(GO:0004791) |
| 0.2 | 1.4 | GO:0060698 | endoribonuclease inhibitor activity(GO:0060698) |
| 0.2 | 1.8 | GO:0016308 | 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308) |
| 0.2 | 1.8 | GO:0048403 | brain-derived neurotrophic factor binding(GO:0048403) |
| 0.2 | 0.7 | GO:0097016 | L27 domain binding(GO:0097016) |
| 0.2 | 1.3 | GO:0055131 | C3HC4-type RING finger domain binding(GO:0055131) |
| 0.2 | 2.4 | GO:0005229 | intracellular calcium activated chloride channel activity(GO:0005229) |
| 0.2 | 0.7 | GO:0017057 | 6-phosphogluconolactonase activity(GO:0017057) |
| 0.2 | 1.1 | GO:0035614 | snRNA stem-loop binding(GO:0035614) |
| 0.2 | 1.5 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.2 | 0.9 | GO:2001069 | glycogen binding(GO:2001069) |
| 0.2 | 1.5 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
| 0.2 | 3.5 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
| 0.2 | 0.9 | GO:2001070 | glycerophosphocholine phosphodiesterase activity(GO:0047389) starch binding(GO:2001070) |
| 0.2 | 3.4 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.2 | 2.7 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.2 | 2.3 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
| 0.2 | 1.8 | GO:0030976 | thiamine pyrophosphate binding(GO:0030976) |
| 0.2 | 0.8 | GO:0046920 | alpha-(1->3)-fucosyltransferase activity(GO:0046920) |
| 0.2 | 1.6 | GO:0043184 | vascular endothelial growth factor receptor 2 binding(GO:0043184) |
| 0.2 | 3.9 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.2 | 1.0 | GO:0044547 | DNA topoisomerase binding(GO:0044547) |
| 0.2 | 1.1 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
| 0.2 | 3.9 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
| 0.2 | 1.8 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
| 0.2 | 2.4 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.2 | 0.9 | GO:0035242 | histone-arginine N-methyltransferase activity(GO:0008469) protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242) |
| 0.2 | 1.8 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.2 | 0.7 | GO:0008410 | CoA-transferase activity(GO:0008410) |
| 0.2 | 0.5 | GO:0015928 | alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928) |
| 0.2 | 0.5 | GO:0031687 | A2A adenosine receptor binding(GO:0031687) |
| 0.2 | 2.4 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
| 0.2 | 0.7 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
| 0.2 | 1.8 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
| 0.2 | 0.8 | GO:0043262 | adenosine-diphosphatase activity(GO:0043262) |
| 0.2 | 0.5 | GO:0035500 | MH2 domain binding(GO:0035500) |
| 0.2 | 1.1 | GO:0017162 | aryl hydrocarbon receptor binding(GO:0017162) |
| 0.2 | 3.5 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.2 | 1.0 | GO:1990829 | C-rich single-stranded DNA binding(GO:1990829) |
| 0.2 | 0.5 | GO:0001042 | RNA polymerase I core binding(GO:0001042) |
| 0.2 | 1.1 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.2 | 3.6 | GO:0043548 | phosphatidylinositol 3-kinase binding(GO:0043548) |
| 0.2 | 3.3 | GO:0008171 | O-methyltransferase activity(GO:0008171) |
| 0.2 | 3.9 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.2 | 0.8 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
| 0.2 | 2.0 | GO:0004576 | oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.1 | 3.6 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.1 | 0.9 | GO:0000298 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) |
| 0.1 | 3.2 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.1 | 4.8 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
| 0.1 | 2.6 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.1 | 9.7 | GO:0035254 | glutamate receptor binding(GO:0035254) |
| 0.1 | 0.7 | GO:0004439 | phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) |
| 0.1 | 2.4 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.1 | 5.0 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
| 0.1 | 2.4 | GO:0030145 | manganese ion binding(GO:0030145) |
| 0.1 | 1.9 | GO:0042608 | T cell receptor binding(GO:0042608) |
| 0.1 | 2.7 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
| 0.1 | 4.0 | GO:0005112 | Notch binding(GO:0005112) |
| 0.1 | 1.2 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 0.1 | 1.1 | GO:0043024 | ribosomal small subunit binding(GO:0043024) |
| 0.1 | 0.5 | GO:0042895 | antibiotic transporter activity(GO:0042895) |
| 0.1 | 1.1 | GO:0004128 | cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128) |
| 0.1 | 0.6 | GO:0001032 | RNA polymerase III type 3 promoter DNA binding(GO:0001032) |
| 0.1 | 1.6 | GO:0098505 | G-rich strand telomeric DNA binding(GO:0098505) |
| 0.1 | 1.6 | GO:0030957 | Tat protein binding(GO:0030957) |
| 0.1 | 7.4 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.1 | 1.9 | GO:0004033 | aldo-keto reductase (NADP) activity(GO:0004033) |
| 0.1 | 0.6 | GO:0016918 | retinal binding(GO:0016918) |
| 0.1 | 1.3 | GO:0001163 | RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164) |
| 0.1 | 2.1 | GO:0004190 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
| 0.1 | 0.6 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.1 | 3.0 | GO:0008146 | sulfotransferase activity(GO:0008146) |
| 0.1 | 2.1 | GO:0016628 | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628) |
| 0.1 | 2.1 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.1 | 2.3 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.1 | 1.0 | GO:0043995 | histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972) |
| 0.1 | 0.6 | GO:0097001 | ceramide binding(GO:0097001) |
| 0.1 | 0.7 | GO:0015266 | protein channel activity(GO:0015266) |
| 0.1 | 1.0 | GO:0031543 | peptidyl-proline dioxygenase activity(GO:0031543) |
| 0.1 | 3.5 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.1 | 2.7 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.1 | 6.1 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.1 | 0.4 | GO:0047391 | alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391) |
| 0.1 | 0.9 | GO:0016428 | tRNA (cytosine-5-)-methyltransferase activity(GO:0016428) |
| 0.1 | 25.5 | GO:0005085 | guanyl-nucleotide exchange factor activity(GO:0005085) |
| 0.1 | 0.4 | GO:0001851 | complement component C3b binding(GO:0001851) |
| 0.1 | 0.3 | GO:0008192 | RNA guanylyltransferase activity(GO:0008192) |
| 0.1 | 0.3 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
| 0.1 | 8.0 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.1 | 3.2 | GO:0030291 | protein serine/threonine kinase inhibitor activity(GO:0030291) |
| 0.1 | 9.7 | GO:0005516 | calmodulin binding(GO:0005516) |
| 0.1 | 10.1 | GO:0008236 | serine-type peptidase activity(GO:0008236) |
| 0.1 | 0.8 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 0.1 | 0.5 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
| 0.1 | 0.4 | GO:0016004 | phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229) |
| 0.1 | 3.9 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.1 | 3.3 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.1 | 1.1 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
| 0.1 | 1.2 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.1 | 3.5 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.1 | 0.6 | GO:0016312 | inositol bisphosphate phosphatase activity(GO:0016312) |
| 0.1 | 5.5 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
| 0.1 | 0.7 | GO:0016531 | copper chaperone activity(GO:0016531) |
| 0.1 | 1.8 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.1 | 5.1 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 0.1 | 0.3 | GO:0031735 | CCR10 chemokine receptor binding(GO:0031735) |
| 0.1 | 0.3 | GO:0004069 | L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) |
| 0.1 | 0.5 | GO:0033743 | peptide-methionine (R)-S-oxide reductase activity(GO:0033743) |
| 0.1 | 0.6 | GO:0043560 | insulin receptor substrate binding(GO:0043560) |
| 0.1 | 1.5 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.1 | 2.4 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.1 | 1.2 | GO:0005521 | lamin binding(GO:0005521) |
| 0.1 | 0.2 | GO:0005119 | smoothened binding(GO:0005119) |
| 0.1 | 0.7 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
| 0.1 | 1.2 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 0.1 | 0.9 | GO:0016755 | transferase activity, transferring amino-acyl groups(GO:0016755) |
| 0.1 | 0.6 | GO:0019215 | intermediate filament binding(GO:0019215) |
| 0.1 | 0.3 | GO:0016401 | palmitoyl-CoA oxidase activity(GO:0016401) |
| 0.1 | 8.8 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.1 | 1.8 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.1 | 0.4 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.1 | 1.1 | GO:0033549 | MAP kinase phosphatase activity(GO:0033549) |
| 0.1 | 0.2 | GO:0030983 | mismatched DNA binding(GO:0030983) |
| 0.1 | 0.3 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
| 0.1 | 0.4 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
| 0.1 | 1.2 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.1 | 2.1 | GO:0005080 | protein kinase C binding(GO:0005080) |
| 0.1 | 0.3 | GO:0004768 | stearoyl-CoA 9-desaturase activity(GO:0004768) |
| 0.1 | 0.3 | GO:0030144 | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144) |
| 0.1 | 0.2 | GO:0031403 | lithium ion binding(GO:0031403) |
| 0.1 | 0.2 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |
| 0.1 | 4.0 | GO:0004004 | RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) |
| 0.1 | 1.1 | GO:0051721 | protein phosphatase 2A binding(GO:0051721) |
| 0.1 | 0.3 | GO:0009374 | biotin binding(GO:0009374) |
| 0.1 | 1.6 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.1 | 0.2 | GO:0000995 | transcription factor activity, core RNA polymerase III binding(GO:0000995) |
| 0.1 | 0.5 | GO:0030552 | cAMP binding(GO:0030552) |
| 0.1 | 0.9 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.0 | 1.0 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.0 | 0.6 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.0 | 0.0 | GO:0031208 | POZ domain binding(GO:0031208) |
| 0.0 | 0.1 | GO:0030249 | cyclase regulator activity(GO:0010851) guanylate cyclase regulator activity(GO:0030249) |
| 0.0 | 0.4 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.0 | 0.8 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.0 | 1.8 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.0 | 0.1 | GO:0098847 | sequence-specific single stranded DNA binding(GO:0098847) |
| 0.0 | 2.1 | GO:0019003 | GDP binding(GO:0019003) |
| 0.0 | 0.7 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.0 | 1.1 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.0 | 0.4 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 0.0 | 2.1 | GO:0016836 | hydro-lyase activity(GO:0016836) |
| 0.0 | 0.3 | GO:0047429 | nucleoside-triphosphate diphosphatase activity(GO:0047429) |
| 0.0 | 10.1 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
| 0.0 | 1.8 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.0 | 13.9 | GO:0008289 | lipid binding(GO:0008289) |
| 0.0 | 0.9 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
| 0.0 | 2.9 | GO:0016820 | hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820) |
| 0.0 | 0.7 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.0 | 0.7 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 0.0 | 0.9 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.0 | 0.2 | GO:0042285 | UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285) |
| 0.0 | 0.4 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.0 | 1.0 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
| 0.0 | 0.9 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 0.0 | 0.7 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.0 | 0.9 | GO:0004879 | RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531) |
| 0.0 | 0.3 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 0.0 | 0.9 | GO:0008375 | acetylglucosaminyltransferase activity(GO:0008375) |
| 0.0 | 0.3 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
| 0.0 | 1.1 | GO:0008238 | exopeptidase activity(GO:0008238) |
| 0.0 | 0.1 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
| 0.0 | 0.1 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.0 | 0.3 | GO:0045309 | protein phosphorylated amino acid binding(GO:0045309) |
| 0.0 | 1.9 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
| 0.0 | 0.3 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.0 | 0.3 | GO:0043138 | 3'-5' DNA helicase activity(GO:0043138) |
| 0.0 | 0.5 | GO:0005179 | hormone activity(GO:0005179) |
| 0.0 | 0.4 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.0 | 0.3 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.0 | 0.2 | GO:0016868 | intramolecular transferase activity, phosphotransferases(GO:0016868) |
| 0.0 | 2.5 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.0 | 0.0 | GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616) |
| 0.0 | 0.2 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.0 | 0.2 | GO:0030971 | receptor tyrosine kinase binding(GO:0030971) |
| 0.0 | 0.4 | GO:0005262 | calcium channel activity(GO:0005262) |
| 0.0 | 0.1 | GO:0016300 | tRNA (uracil) methyltransferase activity(GO:0016300) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.6 | 81.9 | ST_WNT_CA2_CYCLIC_GMP_PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.7 | 28.0 | PID_EPHRINB_REV_PATHWAY | Ephrin B reverse signaling |
| 0.6 | 8.7 | PID_INTEGRIN2_PATHWAY | Beta2 integrin cell surface interactions |
| 0.5 | 3.9 | PID_IL2_1PATHWAY | IL2-mediated signaling events |
| 0.5 | 6.4 | PID_FAS_PATHWAY | FAS (CD95) signaling pathway |
| 0.4 | 1.5 | ST_IL_13_PATHWAY | Interleukin 13 (IL-13) Pathway |
| 0.4 | 1.8 | PID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY | EGF receptor (ErbB1) signaling pathway |
| 0.3 | 12.3 | PID_RAS_PATHWAY | Regulation of Ras family activation |
| 0.3 | 1.9 | ST_TYPE_I_INTERFERON_PATHWAY | Type I Interferon (alpha/beta IFN) Pathway |
| 0.3 | 14.4 | PID_ERBB1_INTERNALIZATION_PATHWAY | Internalization of ErbB1 |
| 0.2 | 3.4 | ST_ADRENERGIC | Adrenergic Pathway |
| 0.2 | 4.9 | SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES | Genes related to PIP3 signaling in B lymphocytes |
| 0.2 | 8.6 | PID_PI3KCI_PATHWAY | Class I PI3K signaling events |
| 0.2 | 4.6 | PID_TRAIL_PATHWAY | TRAIL signaling pathway |
| 0.2 | 4.8 | PID_PI3K_PLC_TRK_PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
| 0.2 | 3.1 | PID_LPA4_PATHWAY | LPA4-mediated signaling events |
| 0.2 | 4.1 | SA_B_CELL_RECEPTOR_COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
| 0.2 | 5.5 | PID_EPHA_FWDPATHWAY | EPHA forward signaling |
| 0.2 | 5.4 | PID_INTEGRIN3_PATHWAY | Beta3 integrin cell surface interactions |
| 0.2 | 2.5 | PID_INSULIN_GLUCOSE_PATHWAY | Insulin-mediated glucose transport |
| 0.2 | 8.3 | PID_REELIN_PATHWAY | Reelin signaling pathway |
| 0.2 | 18.3 | PID_PDGFRB_PATHWAY | PDGFR-beta signaling pathway |
| 0.2 | 6.5 | PID_CXCR3_PATHWAY | CXCR3-mediated signaling events |
| 0.2 | 8.3 | PID_RHOA_REG_PATHWAY | Regulation of RhoA activity |
| 0.2 | 2.1 | PID_MAPK_TRK_PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.2 | 5.8 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
| 0.1 | 1.5 | PID_UPA_UPAR_PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.1 | 17.4 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 1.5 | PID_SYNDECAN_2_PATHWAY | Syndecan-2-mediated signaling events |
| 0.1 | 3.1 | PID_ARF_3PATHWAY | Arf1 pathway |
| 0.1 | 1.1 | PID_VEGF_VEGFR_PATHWAY | VEGF and VEGFR signaling network |
| 0.1 | 2.4 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.1 | 1.7 | PID_HIF1A_PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.1 | 1.5 | PID_VEGFR1_2_PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
| 0.1 | 0.6 | PID_RAC1_PATHWAY | RAC1 signaling pathway |
| 0.1 | 1.2 | PID_PI3KCI_AKT_PATHWAY | Class I PI3K signaling events mediated by Akt |
| 0.1 | 1.7 | PID_SHP2_PATHWAY | SHP2 signaling |
| 0.1 | 1.3 | PID_IL6_7_PATHWAY | IL6-mediated signaling events |
| 0.1 | 0.5 | PID_IFNG_PATHWAY | IFN-gamma pathway |
| 0.1 | 1.4 | PID_FGF_PATHWAY | FGF signaling pathway |
| 0.1 | 2.3 | PID_AJDISS_2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.0 | 0.8 | PID_CD8_TCR_PATHWAY | TCR signaling in naïve CD8+ T cells |
| 0.0 | 0.3 | PID_NFKAPPAB_ATYPICAL_PATHWAY | Atypical NF-kappaB pathway |
| 0.0 | 0.7 | PID_ALPHA_SYNUCLEIN_PATHWAY | Alpha-synuclein signaling |
| 0.0 | 2.3 | PID_TELOMERASE_PATHWAY | Regulation of Telomerase |
| 0.0 | 0.8 | ST_JNK_MAPK_PATHWAY | JNK MAPK Pathway |
| 0.0 | 0.5 | PID_IL2_PI3K_PATHWAY | IL2 signaling events mediated by PI3K |
| 0.0 | 0.6 | PID_RB_1PATHWAY | Regulation of retinoblastoma protein |
| 0.0 | 0.2 | PID_VEGFR1_PATHWAY | VEGFR1 specific signals |
| 0.0 | 0.9 | PID_ATF2_PATHWAY | ATF-2 transcription factor network |
| 0.0 | 0.5 | PID_RHOA_PATHWAY | RhoA signaling pathway |
| 0.0 | 1.1 | PID_CASPASE_PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 0.8 | PID_HES_HEY_PATHWAY | Notch-mediated HES/HEY network |
| 0.0 | 0.1 | PID_IL12_2PATHWAY | IL12-mediated signaling events |
| 0.0 | 1.1 | PID_MYC_REPRESS_PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 0.8 | PID_LKB1_PATHWAY | LKB1 signaling events |
| 0.0 | 0.1 | PID_RHODOPSIN_PATHWAY | Visual signal transduction: Rods |
| 0.0 | 0.6 | PID_ERA_GENOMIC_PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 0.4 | ST_INTEGRIN_SIGNALING_PATHWAY | Integrin Signaling Pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.4 | 92.6 | REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION | Genes involved in Unblocking of NMDA receptor, glutamate binding and activation |
| 1.6 | 32.6 | REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
| 1.4 | 4.3 | REACTOME_SEROTONIN_RECEPTORS | Genes involved in Serotonin receptors |
| 1.2 | 11.7 | REACTOME_AMINE_LIGAND_BINDING_RECEPTORS | Genes involved in Amine ligand-binding receptors |
| 1.1 | 6.6 | REACTOME_COMMON_PATHWAY | Genes involved in Common Pathway |
| 0.7 | 4.4 | REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
| 0.7 | 5.1 | REACTOME_HS_GAG_DEGRADATION | Genes involved in HS-GAG degradation |
| 0.7 | 11.4 | REACTOME_GABA_A_RECEPTOR_ACTIVATION | Genes involved in GABA A receptor activation |
| 0.7 | 23.3 | REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.7 | 4.6 | REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.6 | 9.0 | REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.5 | 14.2 | REACTOME_OTHER_SEMAPHORIN_INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.5 | 21.3 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.5 | 18.6 | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.4 | 7.8 | REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.4 | 3.9 | REACTOME_PLATELET_CALCIUM_HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.4 | 17.7 | REACTOME_DARPP_32_EVENTS | Genes involved in DARPP-32 events |
| 0.3 | 3.1 | REACTOME_GAP_JUNCTION_DEGRADATION | Genes involved in Gap junction degradation |
| 0.3 | 4.9 | REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
| 0.3 | 4.5 | REACTOME_REGULATION_OF_IFNA_SIGNALING | Genes involved in Regulation of IFNA signaling |
| 0.3 | 6.4 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.3 | 12.0 | REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.3 | 2.3 | REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS | Genes involved in Tandem pore domain potassium channels |
| 0.3 | 10.5 | REACTOME_SYNTHESIS_OF_PA | Genes involved in Synthesis of PA |
| 0.3 | 3.9 | REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.3 | 7.7 | REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.3 | 2.2 | REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION | Genes involved in FGFR4 ligand binding and activation |
| 0.3 | 4.5 | REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.3 | 1.4 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PI | Genes involved in Acyl chain remodelling of PI |
| 0.3 | 3.1 | REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY | Genes involved in Adenylate cyclase activating pathway |
| 0.3 | 6.6 | REACTOME_METAL_ION_SLC_TRANSPORTERS | Genes involved in Metal ion SLC transporters |
| 0.3 | 4.0 | REACTOME_SIGNALING_BY_NOTCH4 | Genes involved in Signaling by NOTCH4 |
| 0.3 | 1.5 | REACTOME_REGULATION_OF_IFNG_SIGNALING | Genes involved in Regulation of IFNG signaling |
| 0.2 | 4.2 | REACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM | Genes involved in Heparan sulfate/heparin (HS-GAG) metabolism |
| 0.2 | 2.9 | REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.2 | 5.6 | REACTOME_GLUTATHIONE_CONJUGATION | Genes involved in Glutathione conjugation |
| 0.2 | 7.8 | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.2 | 8.4 | REACTOME_TRIGLYCERIDE_BIOSYNTHESIS | Genes involved in Triglyceride Biosynthesis |
| 0.2 | 2.3 | REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
| 0.2 | 2.9 | REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.2 | 3.1 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
| 0.2 | 5.8 | REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.2 | 1.5 | REACTOME_PD1_SIGNALING | Genes involved in PD-1 signaling |
| 0.2 | 4.3 | REACTOME_CHOLESTEROL_BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.2 | 0.6 | REACTOME_ERK_MAPK_TARGETS | Genes involved in ERK/MAPK targets |
| 0.1 | 0.7 | REACTOME_BASIGIN_INTERACTIONS | Genes involved in Basigin interactions |
| 0.1 | 0.4 | REACTOME_OLFACTORY_SIGNALING_PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.1 | 5.5 | REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.1 | 2.6 | REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 0.1 | 5.0 | REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.1 | 0.5 | REACTOME_CS_DS_DEGRADATION | Genes involved in CS/DS degradation |
| 0.1 | 1.4 | REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
| 0.1 | 3.2 | REACTOME_FRS2_MEDIATED_CASCADE | Genes involved in FRS2-mediated cascade |
| 0.1 | 0.2 | REACTOME_SHC_RELATED_EVENTS | Genes involved in SHC-related events |
| 0.1 | 2.2 | REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS | Genes involved in Trafficking of AMPA receptors |
| 0.1 | 1.9 | REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.1 | 3.5 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.1 | 5.3 | REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES | Genes involved in Cross-presentation of soluble exogenous antigens (endosomes) |
| 0.1 | 1.1 | REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.1 | 1.1 | REACTOME_AMINE_DERIVED_HORMONES | Genes involved in Amine-derived hormones |
| 0.1 | 2.1 | REACTOME_MICRORNA_MIRNA_BIOGENESIS | Genes involved in MicroRNA (miRNA) Biogenesis |
| 0.1 | 1.1 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 0.1 | 2.5 | REACTOME_DEADENYLATION_OF_MRNA | Genes involved in Deadenylation of mRNA |
| 0.1 | 8.2 | REACTOME_POTASSIUM_CHANNELS | Genes involved in Potassium Channels |
| 0.1 | 2.4 | REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT | Genes involved in ABC-family proteins mediated transport |
| 0.1 | 0.4 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PG | Genes involved in Acyl chain remodelling of PG |
| 0.1 | 1.8 | REACTOME_METABOLISM_OF_PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.1 | 5.8 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | Genes involved in NRAGE signals death through JNK |
| 0.1 | 1.6 | REACTOME_SYNTHESIS_OF_PC | Genes involved in Synthesis of PC |
| 0.1 | 0.4 | REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
| 0.1 | 0.8 | REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX | Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex |
| 0.1 | 1.8 | REACTOME_INTERFERON_ALPHA_BETA_SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.1 | 1.4 | REACTOME_INSULIN_RECEPTOR_RECYCLING | Genes involved in Insulin receptor recycling |
| 0.1 | 3.3 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.1 | 3.0 | REACTOME_G_ALPHA_S_SIGNALLING_EVENTS | Genes involved in G alpha (s) signalling events |
| 0.1 | 1.4 | REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION | Genes involved in RNA Polymerase I Transcription Termination |
| 0.1 | 0.7 | REACTOME_INFLAMMASOMES | Genes involved in Inflammasomes |
| 0.1 | 2.8 | REACTOME_INTEGRATION_OF_ENERGY_METABOLISM | Genes involved in Integration of energy metabolism |
| 0.1 | 0.6 | REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
| 0.0 | 0.5 | REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.0 | 0.9 | REACTOME_PIP3_ACTIVATES_AKT_SIGNALING | Genes involved in PIP3 activates AKT signaling |
| 0.0 | 1.4 | REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
| 0.0 | 0.6 | REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.0 | 0.3 | REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
| 0.0 | 0.4 | REACTOME_COPI_MEDIATED_TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.0 | 0.2 | REACTOME_ERKS_ARE_INACTIVATED | Genes involved in ERKs are inactivated |
| 0.0 | 0.7 | REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
| 0.0 | 1.1 | REACTOME_SIGNALING_BY_ROBO_RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.0 | 2.2 | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT | Genes involved in Respiratory electron transport |
| 0.0 | 0.2 | REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter |
| 0.0 | 0.5 | REACTOME_NEPHRIN_INTERACTIONS | Genes involved in Nephrin interactions |
| 0.0 | 3.0 | REACTOME_MRNA_SPLICING | Genes involved in mRNA Splicing |
| 0.0 | 0.5 | REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING | Genes involved in Growth hormone receptor signaling |
| 0.0 | 0.4 | REACTOME_SIGNALING_BY_HIPPO | Genes involved in Signaling by Hippo |
| 0.0 | 0.2 | REACTOME_MEIOTIC_RECOMBINATION | Genes involved in Meiotic Recombination |
| 0.0 | 0.4 | REACTOME_PYRIMIDINE_METABOLISM | Genes involved in Pyrimidine metabolism |
| 0.0 | 0.1 | REACTOME_FORMATION_OF_TRANSCRIPTION_COUPLED_NER_TC_NER_REPAIR_COMPLEX | Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex |
| 0.0 | 1.0 | REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.0 | 0.4 | REACTOME_TIGHT_JUNCTION_INTERACTIONS | Genes involved in Tight junction interactions |
| 0.0 | 0.1 | REACTOME_KERATAN_SULFATE_BIOSYNTHESIS | Genes involved in Keratan sulfate biosynthesis |
| 0.0 | 0.1 | REACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS | Genes involved in Post NMDA receptor activation events |
