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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr4_-_137766474	9.793	ENSMUST00000139951.1	Alpl	alkaline phosphatase, liver/bone/kidney
chr14_-_118052235	9.413	ENSMUST00000022725.2	Dct	dopachrome tautomerase
chr4_+_154960915	6.782	ENSMUST00000049621.6	Hes5	hairy and enhancer of split 5 (Drosophila)
chr5_+_3344194	5.775	ENSMUST00000042410.4	Cdk6	cyclin-dependent kinase 6
chr5_+_3343893	5.673	ENSMUST00000165117.1	Cdk6	cyclin-dependent kinase 6
chr2_+_91259822	5.382	ENSMUST00000138470.1	Pacsin3	protein kinase C and casein kinase substrate in neurons 3
chr11_+_78322965	4.509	ENSMUST00000017534.8	Aldoc	aldolase C, fructose-bisphosphate
chr13_-_116309639	3.114	ENSMUST00000036060.6	Isl1	ISL1 transcription factor, LIM/homeodomain
chr14_-_31640878	3.020	ENSMUST00000167066.1 ENSMUST00000127204.2 ENSMUST00000022437.8	Hacl1	2-hydroxyacyl-CoA lyase 1
chr17_+_35861318	2.771	ENSMUST00000074259.8 ENSMUST00000174873.1	Nrm	nurim (nuclear envelope membrane protein)
chr11_-_68973840	2.756	ENSMUST00000038644.4	Rangrf	RAN guanine nucleotide release factor
chr4_-_141053660	2.717	ENSMUST00000040222.7	Crocc	ciliary rootlet coiled-coil, rootletin
chr11_-_52282564	2.395	ENSMUST00000086844.3	Tcf7	transcription factor 7, T cell specific
chr17_+_35861343	2.246	ENSMUST00000172931.1	Nrm	nurim (nuclear envelope membrane protein)
chr2_+_164562579	2.145	ENSMUST00000017867.3 ENSMUST00000109344.2 ENSMUST00000109345.2	Wfdc2	WAP four-disulfide core domain 2
chr17_-_58991343	2.108	ENSMUST00000025064.7	2610034M16Rik	RIKEN cDNA 2610034M16 gene
chr13_+_3361029	2.044	ENSMUST00000179981.1	Gm16505	predicted gene 16505
chr1_+_44551483	1.731	ENSMUST00000074525.3	Gulp1	GULP, engulfment adaptor PTB domain containing 1
chr5_+_77265454	1.674	ENSMUST00000080359.5	Rest	RE1-silencing transcription factor
chr2_-_51972990	1.412	ENSMUST00000145481.1 ENSMUST00000112705.2	Nmi	N-myc (and STAT) interactor
chr10_-_22149270	1.395	ENSMUST00000179054.1 ENSMUST00000069372.6	E030030I06Rik	RIKEN cDNA E030030I06 gene
chr9_+_50617516	1.318	ENSMUST00000141366.1	Pih1d2	PIH1 domain containing 2
chr13_-_23562369	1.309	ENSMUST00000105107.1	Hist1h3e	histone cluster 1, H3e
chr7_-_15879844	1.287	ENSMUST00000172758.1 ENSMUST00000044434.6	Crx	cone-rod homeobox containing gene
chr4_-_133968611	1.280	ENSMUST00000102552.1	Hmgn2	high mobility group nucleosomal binding domain 2
chr7_-_133015248	1.243	ENSMUST00000169570.1	Ctbp2	C-terminal binding protein 2
chr13_+_23752267	1.233	ENSMUST00000091703.2	Hist1h3b	histone cluster 1, H3b
chr3_-_103737995	1.231	ENSMUST00000029440.8	Olfml3	olfactomedin-like 3
chr19_-_12765447	1.198	ENSMUST00000112933.1	Cntf	ciliary neurotrophic factor
chr13_-_97747373	1.150	ENSMUST00000123535.1	5330416C01Rik	RIKEN cDNA 5330416C01 gene
chr8_-_113848615	1.093	ENSMUST00000093113.4	Adamts18	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18
chr1_-_44218952	1.077	ENSMUST00000054801.3	Mettl21e	methyltransferase like 21E
chr2_-_51973219	1.068	ENSMUST00000028314.2	Nmi	N-myc (and STAT) interactor
chr13_-_21783391	1.067	ENSMUST00000099704.3	Hist1h3i	histone cluster 1, H3i
chr2_-_121456693	1.057	ENSMUST00000110613.2 ENSMUST00000056312.3	Serinc4	serine incorporator 4
chrX_+_134585644	1.024	ENSMUST00000113211.1	Rpl36a	ribosomal protein L36A
chr11_-_90687572	1.008	ENSMUST00000107869.2 ENSMUST00000154599.1 ENSMUST00000107868.1 ENSMUST00000020849.2	Tom1l1	target of myb1-like 1 (chicken)
chr1_+_44551650	1.005	ENSMUST00000160854.1	Gulp1	GULP, engulfment adaptor PTB domain containing 1
chr7_-_105752193	0.960	ENSMUST00000033184.4	Tpp1	tripeptidyl peptidase I
chr10_+_80292453	0.951	ENSMUST00000068408.7 ENSMUST00000062674.6	Rps15	ribosomal protein S15
chr4_-_141053704	0.906	ENSMUST00000102491.3	Crocc	ciliary rootlet coiled-coil, rootletin
chr16_-_35490873	0.901	ENSMUST00000023550.7	Pdia5	protein disulfide isomerase associated 5
chr2_+_121456963	0.866	ENSMUST00000126764.1	Hypk	huntingtin interacting protein K
chr9_-_60838200	0.858	ENSMUST00000063858.7	Gm9869	predicted gene 9869
chr11_+_98026695	0.805	ENSMUST00000092425.4	Rpl19	ribosomal protein L19
chr19_-_47919269	0.799	ENSMUST00000095998.5	Itprip	inositol 1,4,5-triphosphate receptor interacting protein
chr1_+_12692430	0.764	ENSMUST00000180062.1 ENSMUST00000177608.1	Sulf1	sulfatase 1
chrX_-_23285532	0.672	ENSMUST00000115319.2	Klhl13	kelch-like 13
chr1_-_155232710	0.666	ENSMUST00000035914.3	BC034090	cDNA sequence BC034090
chr5_-_96161990	0.650	ENSMUST00000155901.1	Cnot6l	CCR4-NOT transcription complex, subunit 6-like
chr1_-_168431695	0.617	ENSMUST00000176790.1	Pbx1	pre B cell leukemia homeobox 1
chr19_+_43752996	0.577	ENSMUST00000026199.7 ENSMUST00000112047.3 ENSMUST00000153295.1	Cutc	cutC copper transporter homolog (E.coli)
chr4_+_84884418	0.561	ENSMUST00000169371.2	Cntln	centlein, centrosomal protein
chr8_+_13405080	0.520	ENSMUST00000033827.7	Grk1	G protein-coupled receptor kinase 1
chr2_-_73486456	0.512	ENSMUST00000141264.1	Wipf1	WAS/WASL interacting protein family, member 1
chr19_+_46056539	0.433	ENSMUST00000111899.1 ENSMUST00000099392.3 ENSMUST00000062322.4	Pprc1	peroxisome proliferative activated receptor, gamma, coactivator-related 1
chr11_+_23256566	0.395	ENSMUST00000136235.1	Xpo1	exportin 1, CRM1 homolog (yeast)
chr13_-_97747399	0.381	ENSMUST00000144993.1	5330416C01Rik	RIKEN cDNA 5330416C01 gene
chr7_+_101969796	0.368	ENSMUST00000084852.5	Numa1	nuclear mitotic apparatus protein 1
chr19_+_36083696	0.356	ENSMUST00000025714.7	Rpp30	ribonuclease P/MRP 30 subunit
chr11_+_113659283	0.333	ENSMUST00000137878.1	Cog1	component of oligomeric golgi complex 1
chr8_+_78509319	0.330	ENSMUST00000034111.8	Slc10a7	solute carrier family 10 (sodium/bile acid cotransporter family), member 7
chr16_-_76403673	0.328	ENSMUST00000052867.7	Gm9843	predicted gene 9843
chr14_-_54617993	0.277	ENSMUST00000022803.4	Psmb5	proteasome (prosome, macropain) subunit, beta type 5
chr11_-_5099036	0.276	ENSMUST00000102930.3	Ewsr1	Ewing sarcoma breakpoint region 1
chr19_-_53371766	0.274	ENSMUST00000086887.1	Gm10197	predicted gene 10197
chr7_+_13398115	0.239	ENSMUST00000005791.7	Cabp5	calcium binding protein 5
chr2_-_30093642	0.218	ENSMUST00000102865.4	Zdhhc12	zinc finger, DHHC domain containing 12
chr11_-_5099053	0.198	ENSMUST00000093365.5 ENSMUST00000073308.4	Ewsr1	Ewing sarcoma breakpoint region 1
chr16_-_4213404	0.197	ENSMUST00000023165.6	Crebbp	CREB binding protein
chr2_-_30093607	0.178	ENSMUST00000081838.6	Zdhhc12	zinc finger, DHHC domain containing 12
chr7_-_127725616	0.178	ENSMUST00000076091.2	Ctf2	cardiotrophin 2
chr2_-_9883993	0.164	ENSMUST00000114915.2	9230102O04Rik	RIKEN cDNA 9230102O04 gene
chr11_-_5099223	0.162	ENSMUST00000079949.6	Ewsr1	Ewing sarcoma breakpoint region 1
chr15_-_74734313	0.159	ENSMUST00000023260.3	Lypd2	Ly6/Plaur domain containing 2
chr1_-_168431502	0.154	ENSMUST00000064438.4	Pbx1	pre B cell leukemia homeobox 1
chr7_-_25398697	0.131	ENSMUST00000105177.2 ENSMUST00000149349.1	Lipe	lipase, hormone sensitive
chr14_-_105177280	0.130	ENSMUST00000100327.3 ENSMUST00000022715.7	Rbm26	RNA binding motif protein 26
chr7_-_80403315	0.127	ENSMUST00000147150.1	Furin	furin (paired basic amino acid cleaving enzyme)
chr6_+_136954521	0.126	ENSMUST00000137768.1	Pde6h	phosphodiesterase 6H, cGMP-specific, cone, gamma
chr13_+_75089826	0.126	ENSMUST00000022075.4	Pcsk1	proprotein convertase subtilisin/kexin type 1
chr1_+_178187417	0.100	ENSMUST00000161075.1 ENSMUST00000027783.7	Desi2	desumoylating isopeptidase 2
chr11_+_4186789	0.053	ENSMUST00000041042.6 ENSMUST00000180088.1	Tbc1d10a	TBC1 domain family, member 10a
chr2_+_91265252	0.052	ENSMUST00000028691.6	Arfgap2	ADP-ribosylation factor GTPase activating protein 2
chr4_-_139833524	0.015	ENSMUST00000030508.7	Pax7	paired box gene 7
chr7_+_126976338	0.014	ENSMUST00000032920.3	Cdipt	CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.7	6.8	GO:2000974	negative regulation of pro-B cell differentiation(GO:2000974)
1.6	11.4	GO:0044838	cell quiescence(GO:0044838)
1.6	9.4	GO:0006570	tyrosine metabolic process(GO:0006570)
1.0	3.1	GO:0032650	regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) cardiac cell fate determination(GO:0060913)
0.9	3.6	GO:0032053	ciliary basal body organization(GO:0032053)
0.8	2.5	GO:1902524	interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.6	3.0	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.5	2.8	GO:0086028	bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
0.5	4.5	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.4	1.7	GO:2000705	regulation of dense core granule biogenesis(GO:2000705)
0.4	1.2	GO:0048687	positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.3	2.4	GO:0002681	somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.2	9.8	GO:0046677	response to antibiotic(GO:0046677)
0.2	5.4	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.2	0.8	GO:0014846	esophagus smooth muscle contraction(GO:0014846)
0.2	0.5	GO:0016056	photoreceptor cell morphogenesis(GO:0008594) rhodopsin mediated signaling pathway(GO:0016056) post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.1	1.2	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
0.1	3.6	GO:0034723	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1	1.0	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1	0.2	GO:0045358	negative regulation of interferon-beta biosynthetic process(GO:0045358)
0.1	0.4	GO:1904778	regulation of metaphase plate congression(GO:0090235) regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1	1.1	GO:0090331	negative regulation of platelet aggregation(GO:0090331)
0.1	0.6	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1	1.3	GO:0040034	regulation of development, heterochronic(GO:0040034)
0.0	2.6	GO:0006911	phagocytosis, engulfment(GO:0006911)
0.0	0.1	GO:0046340	diacylglycerol catabolic process(GO:0046340)
0.0	0.6	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	1.0	GO:0031954	positive regulation of protein autophosphorylation(GO:0031954)
0.0	0.6	GO:0055070	copper ion homeostasis(GO:0055070)
0.0	1.0	GO:0043171	peptide catabolic process(GO:0043171)
0.0	0.1	GO:0090472	dibasic protein processing(GO:0090472)
0.0	2.7	GO:0010389	regulation of G2/M transition of mitotic cell cycle(GO:0010389)
0.0	0.4	GO:0001682	tRNA 5'-leader removal(GO:0001682)
0.0	0.8	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.0	0.5	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.0	2.1	GO:0010466	negative regulation of peptidase activity(GO:0010466)
0.0	0.4	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.9	GO:0045454	cell redox homeostasis(GO:0045454)
0.0	0.1	GO:0016486	peptide hormone processing(GO:0016486)
0.0	1.1	GO:0007601	visual perception(GO:0007601)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	9.8	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
0.4	1.2	GO:0097058	CRLF-CLCF1 complex(GO:0097058)
0.3	9.4	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)
0.3	5.0	GO:0005652	nuclear lamina(GO:0005652)
0.2	13.5	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2	3.6	GO:0035253	ciliary rootlet(GO:0035253)
0.1	3.6	GO:0000788	nuclear nucleosome(GO:0000788)
0.1	0.4	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.1	0.4	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.1	1.0	GO:0097470	ribbon synapse(GO:0097470)
0.1	2.4	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	2.8	GO:0014704	intercalated disc(GO:0014704)
0.0	0.6	GO:0030014	CCR4-NOT complex(GO:0030014)
0.0	1.8	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	0.3	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.2	GO:0005642	annulate lamellae(GO:0005642)
0.0	1.7	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	0.2	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	2.5	GO:0005777	peroxisome(GO:0005777) microbody(GO:0042579)
0.0	0.3	GO:0005839	proteasome core complex(GO:0005839)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.8	11.4	GO:0098770	FBXO family protein binding(GO:0098770)
2.4	9.8	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.8	4.5	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.7	9.4	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.4	2.1	GO:0019828	aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.4	5.4	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.3	3.0	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.2	1.0	GO:0008240	tripeptidyl-peptidase activity(GO:0008240)
0.2	1.4	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.2	0.8	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1	0.8	GO:1990932	5.8S rRNA binding(GO:1990932)
0.1	0.5	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.1	1.7	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.1	1.0	GO:0016618	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1	1.3	GO:0043522	leucine zipper domain binding(GO:0043522)
0.1	3.1	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.1	0.9	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.1	1.1	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1	3.6	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.1	3.4	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin binding(GO:0030332)
0.1	3.0	GO:0008536	Ran GTPase binding(GO:0008536)
0.1	1.3	GO:0017160	Ral GTPase binding(GO:0017160)
0.0	0.4	GO:0051011	microtubule minus-end binding(GO:0051011)
0.0	7.0	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	0.6	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.0	0.4	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	2.4	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0	0.1	GO:0042134	rRNA primary transcript binding(GO:0042134)
0.0	1.5	GO:0019894	kinesin binding(GO:0019894)
0.0	1.0	GO:0030295	protein kinase activator activity(GO:0030295)
0.0	0.4	GO:0019707	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0	0.3	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	1.1	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.1	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.6	GO:0005507	copper ion binding(GO:0005507)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	11.4	PID_IL2_STAT5_PATHWAY	IL2 signaling events mediated by STAT5
0.1	6.8	PID_CDC42_PATHWAY	CDC42 signaling events
0.0	0.6	PID_CONE_PATHWAY	Visual signal transduction: Cones
0.0	3.4	WNT_SIGNALING	Genes related to Wnt-mediated signal transduction
0.0	1.2	PID_ARF6_PATHWAY	Arf6 signaling events
0.0	0.6	PID_BARD1_PATHWAY	BARD1 signaling events
0.0	0.7	PID_AURORA_B_PATHWAY	Aurora B signaling
0.0	0.2	PID_RANBP2_PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	1.9	NABA_ECM_REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	11.4	REACTOME_G1_PHASE	Genes involved in G1 Phase
0.2	3.2	REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1	4.5	REACTOME_GLYCOLYSIS	Genes involved in Glycolysis
0.1	3.0	REACTOME_PEROXISOMAL_LIPID_METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.1	7.0	REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1	3.6	REACTOME_RNA_POL_I_PROMOTER_OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.4	REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	1.9	REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	2.8	REACTOME_PEPTIDE_CHAIN_ELONGATION	Genes involved in Peptide chain elongation
0.0	0.2	REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.1	REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins

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