Motif ID: Gzf1

Z-value: 0.429


Transcription factors associated with Gzf1:

Gene SymbolEntrez IDGene Name
Gzf1 ENSMUSG00000027439.9 Gzf1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gzf1mm10_v2_chr2_+_148681023_148681197-0.358.8e-03Click!


Activity profile for motif Gzf1.

activity profile for motif Gzf1


Sorted Z-values histogram for motif Gzf1

Sorted Z-values for motif Gzf1



Network of associatons between targets according to the STRING database.



First level regulatory network of Gzf1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_154960915 8.355 ENSMUST00000049621.6
 Hes5
hairy and enhancer of split 5 (Drosophila)
chr2_-_93996354 2.330 ENSMUST00000183110.1
 Gm27027
predicted gene, 27027
chr17_+_47594629 2.234 ENSMUST00000182846.1
 Ccnd3
cyclin D3
chr11_-_33163072 1.659 ENSMUST00000093201.6
ENSMUST00000101375.4
ENSMUST00000109354.3
ENSMUST00000075641.3
 Npm1



nucleophosmin 1



chr14_+_19751257 1.536 ENSMUST00000022340.3
 Nid2
nidogen 2
chr4_-_129542710 1.443 ENSMUST00000102597.4
 Hdac1
histone deacetylase 1
chr13_+_37826225 1.174 ENSMUST00000128570.1
 Rreb1
ras responsive element binding protein 1
chr7_-_30612731 1.125 ENSMUST00000006476.4
 Upk1a
uroplakin 1A
chr17_-_55915870 1.054 ENSMUST00000074828.4
 Rpl21-ps6
ribosomal protein L21, pseudogene 6
chr16_+_65815508 1.015 ENSMUST00000168064.1
 Vgll3
vestigial like 3 (Drosophila)
chr14_+_55854115 0.826 ENSMUST00000168479.1
 Nynrin
NYN domain and retroviral integrase containing
chr8_-_78508876 0.760 ENSMUST00000049245.7
 Rbmxl1
RNA binding motif protein, X linked-like-1
chr14_+_11227511 0.723 ENSMUST00000080237.3
 Rpl21-ps4
ribosomal protein L21, pseudogene 4
chr2_+_162931520 0.699 ENSMUST00000130411.1
 Srsf6
serine/arginine-rich splicing factor 6
chr14_+_55853997 0.668 ENSMUST00000100529.3
 Nynrin
NYN domain and retroviral integrase containing
chr1_+_15805639 0.656 ENSMUST00000027057.6
 Terf1
telomeric repeat binding factor 1
chr8_+_105855086 0.621 ENSMUST00000040445.7
 Thap11
THAP domain containing 11
chr4_+_129513581 0.519 ENSMUST00000062356.6
 Marcksl1
MARCKS-like 1
chr4_-_134128707 0.443 ENSMUST00000105879.1
ENSMUST00000030651.8
 Sh3bgrl3

SH3 domain binding glutamic acid-rich protein-like 3

chr12_+_109540979 0.205 ENSMUST00000129245.1
ENSMUST00000143836.1
ENSMUST00000124106.1
 Meg3


maternally expressed 3


chr17_+_71204647 0.163 ENSMUST00000126681.1
 Lpin2
lipin 2
chr2_+_29827342 0.070 ENSMUST00000091142.3
 Urm1
ubiquitin related modifier 1 homolog (S. cerevisiae)
chr8_+_78509319 0.056 ENSMUST00000034111.8
 Slc10a7
solute carrier family 10 (sodium/bile acid cotransporter family), member 7
chr10_+_82699007 0.021 ENSMUST00000020478.7
 Hcfc2
host cell factor C2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 8.4 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
0.6 1.7 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448) rRNA export from nucleus(GO:0006407)
0.2 1.4 GO:0061198 fungiform papilla formation(GO:0061198) positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.2 1.5 GO:0015074 DNA integration(GO:0015074)
0.2 0.7 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.2 0.7 GO:0097694 establishment of RNA localization to telomere(GO:0097694)
0.1 1.2 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.1 2.2 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.8 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.1 GO:0034227 tRNA thio-modification(GO:0034227)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0001652 granular component(GO:0001652)
0.1 0.8 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.7 GO:0070187 telosome(GO:0070187)
0.1 1.4 GO:0016580 Sin3 complex(GO:0016580)
0.0 2.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.5 GO:0005604 basement membrane(GO:0005604)
0.0 0.6 GO:0045171 intercellular bridge(GO:0045171)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.4 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.2 1.7 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.7 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 2.2 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 9.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.2 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.7 GO:0036002 pre-mRNA binding(GO:0036002)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 8.4 PID_CDC42_PATHWAY CDC42 signaling events
0.1 2.2 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 1.5 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 1.7 PID_BARD1_PATHWAY BARD1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.1 9.8 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 2.2 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 1.7 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.7 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.2 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE