Motif ID: Hbp1

Z-value: 0.637


Transcription factors associated with Hbp1:

Gene SymbolEntrez IDGene Name
Hbp1 ENSMUSG00000002996.11 Hbp1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hbp1mm10_v2_chr12_-_31950210_31950246-0.375.1e-03Click!


Activity profile for motif Hbp1.

activity profile for motif Hbp1


Sorted Z-values histogram for motif Hbp1

Sorted Z-values for motif Hbp1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hbp1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_11609256 2.755 ENSMUST00000052902.7
 Gm9797
predicted pseudogene 9797
chr13_-_66852017 2.352 ENSMUST00000059329.6
 Gm17449
predicted gene, 17449
chr13_-_66851513 2.253 ENSMUST00000169322.1
 Gm17404
predicted gene, 17404
chr7_-_79386943 2.226 ENSMUST00000053718.8
ENSMUST00000179243.1
 Rlbp1

retinaldehyde binding protein 1

chr10_+_57784914 1.926 ENSMUST00000165013.1
 Fabp7
fatty acid binding protein 7, brain
chr19_+_38481057 1.773 ENSMUST00000182481.1
 Plce1
phospholipase C, epsilon 1
chr10_+_57784859 1.510 ENSMUST00000020024.5
 Fabp7
fatty acid binding protein 7, brain
chr13_+_65512678 1.454 ENSMUST00000081471.2
 Gm10139
predicted gene 10139
chr15_-_66812593 1.417 ENSMUST00000100572.3
 Sla
src-like adaptor
chr4_-_14621805 1.407 ENSMUST00000042221.7
 Slc26a7
solute carrier family 26, member 7
chr4_-_58499398 1.182 ENSMUST00000107570.1
 Lpar1
lysophosphatidic acid receptor 1
chr19_-_32466575 1.133 ENSMUST00000078034.3
 Rpl9-ps6
ribosomal protein L9, pseudogene 6
chr17_-_32166879 1.087 ENSMUST00000087723.3
 Notch3
notch 3
chr10_+_14523062 1.072 ENSMUST00000096020.5
 Gm10335
predicted gene 10335
chr12_-_10900296 1.049 ENSMUST00000085735.2
 Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chr13_-_113046357 1.047 ENSMUST00000022282.3
 Gpx8
glutathione peroxidase 8 (putative)
chr8_+_12395287 1.036 ENSMUST00000180353.1
 Sox1
SRY-box containing gene 1
chrY_-_1245753 1.033 ENSMUST00000154004.1
 Uty
ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome
chr11_-_7213897 1.005 ENSMUST00000020702.4
ENSMUST00000135887.2
 Igfbp3

insulin-like growth factor binding protein 3

chr3_+_121953213 0.998 ENSMUST00000037958.7
ENSMUST00000128366.1
 Arhgap29

Rho GTPase activating protein 29


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 176 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 3.4 GO:0060134 prepulse inhibition(GO:0060134)
0.0 2.2 GO:0007601 visual perception(GO:0007601)
0.3 2.0 GO:0072103 glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.3 1.9 GO:0019532 oxalate transport(GO:0019532)
0.1 1.9 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 1.8 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 1.8 GO:0032835 glomerulus development(GO:0032835)
0.1 1.5 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 1.4 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.2 1.3 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 1.3 GO:0051384 response to glucocorticoid(GO:0051384)
0.3 1.2 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.3 1.0 GO:2000832 androgen secretion(GO:0035935) testosterone secretion(GO:0035936) positive regulation of apoptotic DNA fragmentation(GO:1902512) negative regulation of steroid hormone secretion(GO:2000832) regulation of androgen secretion(GO:2000834) regulation of testosterone secretion(GO:2000843)
0.1 1.0 GO:0001553 luteinization(GO:0001553)
0.0 1.0 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 1.0 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 1.0 GO:0006414 translational elongation(GO:0006414)
0.2 0.9 GO:0035795 negative regulation of mitochondrial membrane permeability(GO:0035795)
0.2 0.9 GO:0071499 response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)
0.0 0.9 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 68 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.4 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 2.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 2.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 2.1 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 2.0 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 1.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 1.4 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 1.4 GO:0070469 respiratory chain(GO:0070469)
0.3 1.0 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 1.0 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.0 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.0 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.0 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 0.9 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.9 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 0.9 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.2 0.8 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.8 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.8 GO:0005839 proteasome core complex(GO:0005839)
0.2 0.7 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 144 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.4 GO:0005504 fatty acid binding(GO:0005504)
0.1 2.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.3 2.2 GO:0016918 retinal binding(GO:0016918)
0.2 1.9 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
0.1 1.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 1.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 1.5 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 1.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.3 GO:0051087 chaperone binding(GO:0051087)
0.2 1.2 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.1 1.2 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.0 1.1 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.2 1.0 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 1.0 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 1.0 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 0.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.9 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.9 GO:0051059 NF-kappaB binding(GO:0051059)
0.3 0.8 GO:0016748 succinyltransferase activity(GO:0016748)
0.2 0.8 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.7 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 1.7 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 1.4 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events
0.0 1.0 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.0 PID_PLK1_PATHWAY PLK1 signaling events
0.0 0.9 PID_CXCR3_PATHWAY CXCR3-mediated signaling events
0.0 0.8 PID_BARD1_PATHWAY BARD1 signaling events
0.0 0.8 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 0.7 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.7 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 0.7 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.6 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 0.6 PID_ATM_PATHWAY ATM pathway
0.0 0.5 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.5 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.5 PID_SHP2_PATHWAY SHP2 signaling
0.0 0.4 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.4 PID_MYC_PATHWAY C-MYC pathway
0.0 0.4 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.3 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 49 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.9 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.0 2.4 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 2.4 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 2.1 REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.1 2.0 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 1.6 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.4 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.1 1.3 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.2 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 1.0 REACTOME_ACYL_CHAIN_REMODELLING_OF_PS Genes involved in Acyl chain remodelling of PS
0.0 0.9 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.1 0.8 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.0 0.8 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.2 0.7 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.1 0.7 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.0 0.7 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.7 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.7 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.7 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.1 0.6 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1