Z-value: 5.499
Transcription factors associated with Hdx:
Activity-expression correlation:
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Showing 1 to 20 of 87 entries
Gene overrepresentation in biological_process category:
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Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihood Term Description
0.1
1936.1
GO:0008150
biological_process(GO:0008150)
4.1
24.4
GO:0021797
forebrain anterior/posterior pattern specification(GO:0021797)
0.3
11.9
GO:0010972
negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.4
11.6
GO:0034723
DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
3.8
11.5
GO:1990046
positive regulation of mitochondrial DNA replication(GO:0090297) regulation of cardiolipin metabolic process(GO:1900208) positive regulation of cardiolipin metabolic process(GO:1900210) stress-induced mitochondrial fusion(GO:1990046)
2.1
10.7
GO:0021905
pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
0.4
8.8
GO:2000001
regulation of DNA damage checkpoint(GO:2000001)
2.8
8.5
GO:0046381
CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.2
7.9
GO:0006270
DNA replication initiation(GO:0006270)
0.1
7.9
GO:0021884
forebrain neuron development(GO:0021884)
1.3
5.1
GO:0006166
purine ribonucleoside salvage(GO:0006166)
0.2
4.7
GO:0043486
histone exchange(GO:0043486)
0.6
4.5
GO:0006344
maintenance of chromatin silencing(GO:0006344)
0.9
4.4
GO:0019659
fermentation(GO:0006113) lactate biosynthetic process from pyruvate(GO:0019244) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.4
4.1
GO:0018230
peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1
3.5
GO:0060009
Sertoli cell development(GO:0060009)
0.5
3.4
GO:0061087
positive regulation of histone H3-K27 methylation(GO:0061087)
0.1
3.0
GO:1902857
positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1
2.6
GO:2001224
positive regulation of neuron migration(GO:2001224)
0.6
2.3
GO:0007171
activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
Gene overrepresentation in cellular_component category:
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Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihood Term Description
0.1
2004.2
GO:0005575
cellular_component(GO:0005575)
0.4
11.6
GO:0000788
nuclear nucleosome(GO:0000788)
0.7
11.5
GO:0042101
T cell receptor complex(GO:0042101)
1.5
8.8
GO:0032299
ribonuclease H2 complex(GO:0032299)
1.3
7.9
GO:0001674
female germ cell nucleus(GO:0001674)
0.2
4.5
GO:0071564
npBAF complex(GO:0071564)
0.3
4.4
GO:0035686
sperm fibrous sheath(GO:0035686)
0.8
3.4
GO:0032021
NELF complex(GO:0032021)
0.3
3.4
GO:0001739
sex chromatin(GO:0001739)
0.1
3.1
GO:0030285
integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.2
3.0
GO:0031105
septin complex(GO:0031105)
0.4
1.5
GO:0060187
cell pole(GO:0060187)
Gene overrepresentation in molecular_function category:
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Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihood Term Description
0.1
1975.9
GO:0003674
molecular_function(GO:0003674)
0.1
26.3
GO:0001078
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2
11.6
GO:0031492
nucleosomal DNA binding(GO:0031492)
1.6
11.5
GO:1901612
phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.7
10.7
GO:0003680
AT DNA binding(GO:0003680)
0.5
9.0
GO:0004181
metallocarboxypeptidase activity(GO:0004181)
1.3
8.8
GO:0004523
RNA-DNA hybrid ribonuclease activity(GO:0004523)
2.8
8.5
GO:0016716
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.3
5.8
GO:0004198
calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
1.7
5.1
GO:0004731
purine-nucleoside phosphorylase activity(GO:0004731)
0.5
4.7
GO:0005068
transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1
4.5
GO:0031491
nucleosome binding(GO:0031491)
1.1
4.4
GO:0004459
L-lactate dehydrogenase activity(GO:0004459)
0.1
4.1
GO:0019707
protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.5
3.4
GO:0046976
histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.2
3.0
GO:0031418
L-ascorbic acid binding(GO:0031418)
0.1
2.6
GO:0030215
semaphorin receptor binding(GO:0030215)
0.4
2.2
GO:0043532
angiostatin binding(GO:0043532)
0.1
1.4
GO:0017176
phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.2
1.1
GO:0016813
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
Gene overrepresentation in C2:CP category:
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Showing 1 to 6 of 6 entries
Gene overrepresentation in C2:CP:REACTOME category:
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Showing 1 to 13 of 13 entries