Motif ID: Hinfp

Z-value: 1.890


Transcription factors associated with Hinfp:

Gene SymbolEntrez IDGene Name
Hinfp ENSMUSG00000032119.4 Hinfp

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hinfpmm10_v2_chr9_-_44305595_44305688-0.321.6e-02Click!


Activity profile for motif Hinfp.

activity profile for motif Hinfp


Sorted Z-values histogram for motif Hinfp

Sorted Z-values for motif Hinfp



Network of associatons between targets according to the STRING database.



First level regulatory network of Hinfp

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_+_51645232 21.674 ENSMUST00000075853.5
 Cks2
CDC28 protein kinase regulatory subunit 2
chr11_-_89302545 17.452 ENSMUST00000061728.3
 Nog
noggin
chr5_+_108694222 16.547 ENSMUST00000013633.8
ENSMUST00000112560.3
 Fgfrl1

fibroblast growth factor receptor-like 1

chr11_+_80300866 15.854 ENSMUST00000017836.7
 Rhbdl3
rhomboid, veinlet-like 3 (Drosophila)
chr3_+_87971129 15.062 ENSMUST00000160694.1
 Nes
nestin
chr3_+_87971071 15.025 ENSMUST00000090973.5
 Nes
nestin
chr2_-_91931675 13.402 ENSMUST00000111309.1
 Mdk
midkine
chr9_+_118478344 12.555 ENSMUST00000035020.8
 Eomes
eomesodermin homolog (Xenopus laevis)
chr2_+_84840612 12.552 ENSMUST00000111625.1
 Slc43a1
solute carrier family 43, member 1
chr5_+_33658123 12.542 ENSMUST00000074849.6
ENSMUST00000079534.4
 Tacc3

transforming, acidic coiled-coil containing protein 3

chr7_+_122159422 12.403 ENSMUST00000033154.6
 Plk1
polo-like kinase 1
chr19_-_36919606 11.787 ENSMUST00000057337.7
 Fgfbp3
fibroblast growth factor binding protein 3
chr19_+_25610533 11.768 ENSMUST00000048935.4
 Dmrt3
doublesex and mab-3 related transcription factor 3
chr3_+_69004711 11.550 ENSMUST00000042901.8
 Smc4
structural maintenance of chromosomes 4
chr7_+_67655414 11.548 ENSMUST00000107470.1
 Ttc23
tetratricopeptide repeat domain 23
chr1_+_191821444 11.054 ENSMUST00000027931.7
 Nek2
NIMA (never in mitosis gene a)-related expressed kinase 2
chr14_+_65806066 10.963 ENSMUST00000139644.1
 Pbk
PDZ binding kinase
chr1_+_139454747 10.623 ENSMUST00000053364.8
ENSMUST00000097554.3
 Aspm

asp (abnormal spindle)-like, microcephaly associated (Drosophila)

chr9_+_118478182 10.500 ENSMUST00000111763.1
 Eomes
eomesodermin homolog (Xenopus laevis)
chr4_+_52439235 10.273 ENSMUST00000117280.1
ENSMUST00000102915.3
ENSMUST00000142227.1
 Smc2


structural maintenance of chromosomes 2



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 187 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 32.7 GO:0043524 negative regulation of neuron apoptotic process(GO:0043524)
4.0 31.8 GO:0010032 meiotic chromosome condensation(GO:0010032)
7.7 23.1 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
1.2 20.9 GO:0030953 astral microtubule organization(GO:0030953)
0.4 19.5 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.8 19.1 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
3.7 18.7 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
2.5 17.8 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
4.4 17.5 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
1.5 16.5 GO:0060539 diaphragm development(GO:0060539)
0.3 15.3 GO:0006635 fatty acid beta-oxidation(GO:0006635)
4.5 13.4 GO:0030421 defecation(GO:0030421)
1.1 13.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
3.1 12.4 GO:0040038 polar body extrusion after meiotic divisions(GO:0040038)
3.0 12.1 GO:0006014 D-ribose metabolic process(GO:0006014)
2.0 11.8 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
1.1 11.8 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
3.8 11.4 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
2.8 11.1 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.2 11.0 GO:0070303 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 102 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.9 39.3 GO:0000796 condensin complex(GO:0000796)
0.0 25.7 GO:0005615 extracellular space(GO:0005615)
0.3 23.4 GO:0005643 nuclear pore(GO:0005643)
0.4 21.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.3 17.0 GO:0005882 intermediate filament(GO:0005882)
0.2 15.7 GO:0000794 condensed nuclear chromosome(GO:0000794)
5.2 15.6 GO:0036125 mitochondrial fatty acid beta-oxidation multienzyme complex(GO:0016507) fatty acid beta-oxidation multienzyme complex(GO:0036125)
0.2 15.4 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 13.2 GO:0005829 cytosol(GO:0005829)
0.2 12.9 GO:0005871 kinesin complex(GO:0005871)
3.1 12.4 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.3 12.3 GO:0060077 inhibitory synapse(GO:0060077)
2.1 10.6 GO:0036449 microtubule minus-end(GO:0036449)
0.0 10.6 GO:0005815 microtubule organizing center(GO:0005815)
1.5 10.3 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
1.4 10.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.2 9.7 GO:0016235 aggresome(GO:0016235)
0.2 8.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.2 8.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.4 8.6 GO:0016580 Sin3 complex(GO:0016580)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 120 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 38.6 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 31.5 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
3.3 30.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.4 23.8 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
5.4 21.7 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 20.9 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.6 19.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.2 17.5 GO:0019955 cytokine binding(GO:0019955)
1.8 16.5 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
4.1 16.4 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508)
2.3 16.0 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.2 15.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 13.4 GO:0008083 growth factor activity(GO:0008083)
1.5 13.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.5 13.1 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.2 12.9 GO:0003777 microtubule motor activity(GO:0003777)
2.1 12.4 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.2 11.4 GO:0061650 ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.2 11.4 GO:0005080 protein kinase C binding(GO:0005080)
3.8 11.3 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 26.8 PID_AURORA_B_PATHWAY Aurora B signaling
0.5 26.1 PID_IL12_2PATHWAY IL12-mediated signaling events
0.8 23.5 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.6 23.5 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.6 22.7 PID_AURORA_A_PATHWAY Aurora A signaling
0.4 18.9 PID_BMP_PATHWAY BMP receptor signaling
0.3 15.1 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.4 14.2 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.1 11.8 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.2 10.4 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.1 9.5 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.1 7.1 PID_CMYB_PATHWAY C-MYB transcription factor network
0.1 6.4 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.4 6.3 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.2 6.2 PID_MYC_PATHWAY C-MYC pathway
0.2 5.8 PID_CD40_PATHWAY CD40/CD40L signaling
0.6 5.4 ST_TYPE_I_INTERFERON_PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 5.0 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.2 4.8 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 4.6 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 57 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 21.6 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.6 21.2 REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS Genes involved in Activation of ATR in response to replication stress
0.6 18.9 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
1.0 17.7 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.7 16.0 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.2 15.8 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.7 12.4 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.5 11.1 REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.2 11.1 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.4 8.2 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.6 8.1 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.3 8.0 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.8 7.8 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.3 7.8 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 7.3 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.4 7.2 REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT Genes involved in Ligand-gated ion channel transport
0.3 6.7 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.1 6.0 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 6.0 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.2 5.1 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism