• All motifs sorted by activity significance
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• All promoters sorted by FOV

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: Hlx

Z-value: 0.211

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr9_+_54980880	1.125	ENSMUST00000093844.3	Chrna5	cholinergic receptor, nicotinic, alpha polypeptide 5
chr7_-_45103747	0.836	ENSMUST00000003512.7	Fcgrt	Fc receptor, IgG, alpha chain transporter
chrX_-_143933089	0.648	ENSMUST00000087313.3	Dcx	doublecortin
chr17_-_50094277	0.570	ENSMUST00000113195.1	Rftn1	raftlin lipid raft linker 1
chrX_-_143933204	0.350	ENSMUST00000112851.1 ENSMUST00000112856.2 ENSMUST00000033642.3	Dcx	doublecortin
chr6_+_7555053	0.308	ENSMUST00000090679.2 ENSMUST00000184986.1	Tac1	tachykinin 1
chr1_+_180109192	0.269	ENSMUST00000143176.1 ENSMUST00000135056.1	Cdc42bpa	CDC42 binding protein kinase alpha
chr15_-_8710409	0.262	ENSMUST00000157065.1	Slc1a3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr7_-_34313531	0.181	ENSMUST00000108074.1	4931406P16Rik	RIKEN cDNA 4931406P16 gene
chr5_-_62766153	0.129	ENSMUST00000076623.4	Arap2	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr10_+_102158858	0.114	ENSMUST00000138522.1 ENSMUST00000163753.1 ENSMUST00000138016.1	Mgat4c	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr15_-_8710734	0.110	ENSMUST00000005493.7	Slc1a3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr3_+_32436376	0.085	ENSMUST00000108242.1	Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr19_+_53944870	0.069	ENSMUST00000025932.7	Shoc2	soc-2 (suppressor of clear) homolog (C. elegans)
chr19_-_53944621	0.066	ENSMUST00000135402.2	Bbip1	BBSome interacting protein 1
chrM_+_2743	0.031	ENSMUST00000082392.1	mt-Nd1	mitochondrially encoded NADH dehydrogenase 1

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.1	GO:0035095	behavioral response to nicotine(GO:0035095)
0.1	0.6	GO:0002457	T cell antigen processing and presentation(GO:0002457)
0.1	0.3	GO:0035934	corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.1	0.4	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.1	1.0	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.0	0.1	GO:0044028	DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0	0.1	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.1	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.1	GO:0005943	phosphatidylinositol 3-kinase complex, class IA(GO:0005943)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.8	GO:0019770	IgG receptor activity(GO:0019770)
0.1	1.1	GO:0022848	acetylcholine-gated cation channel activity(GO:0022848)
0.1	0.4	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.0	0.1	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.3	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.0	0.1	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.0	PID_LIS1_PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.1	REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors

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