Motif ID: Hoxa11_Hoxc12

Z-value: 1.043

Transcription factors associated with Hoxa11_Hoxc12:

Gene SymbolEntrez IDGene Name
Hoxa11 ENSMUSG00000038210.9 Hoxa11
Hoxc12 ENSMUSG00000050328.2 Hoxc12






Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa11_Hoxc12

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_35076902 13.462 ENSMUST00000172494.1
ENSMUST00000172678.1
ENSMUST00000013910.4
Ly6g6e


lymphocyte antigen 6 complex, locus G6E


chr1_-_56978534 13.127 ENSMUST00000177282.1
Satb2
special AT-rich sequence binding protein 2
chr6_+_108213086 10.413 ENSMUST00000032192.6
Itpr1
inositol 1,4,5-trisphosphate receptor 1
chr13_+_16014457 9.407 ENSMUST00000164993.1
Inhba
inhibin beta-A
chr14_+_80000292 8.566 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr1_+_43730593 7.136 ENSMUST00000027217.8
1500015O10Rik
RIKEN cDNA 1500015O10 gene
chr17_+_6270475 6.864 ENSMUST00000088940.4
Tmem181a
transmembrane protein 181A
chr16_-_57231434 5.978 ENSMUST00000023431.6
Tbc1d23
TBC1 domain family, member 23
chr9_+_53771499 5.378 ENSMUST00000048670.8
Slc35f2
solute carrier family 35, member F2
chr16_-_45408955 5.294 ENSMUST00000163230.1
Cd200
CD200 antigen
chr7_-_142661858 5.203 ENSMUST00000145896.2
Igf2
insulin-like growth factor 2
chr17_-_6477102 5.067 ENSMUST00000167717.2
Tmem181b-ps
transmembrane protein 181B, pseudogene
chrX_+_73064787 4.953 ENSMUST00000060418.6
Pnma3
paraneoplastic antigen MA3
chr3_-_117360876 4.766 ENSMUST00000061071.8
D3Bwg0562e
DNA segment, Chr 3, Brigham & Women's Genetics 0562 expressed
chr15_-_43869993 4.636 ENSMUST00000067469.4
Tmem74
transmembrane protein 74
chr5_+_66968961 4.570 ENSMUST00000132991.1
Limch1
LIM and calponin homology domains 1
chr14_+_27622433 4.130 ENSMUST00000090302.5
Erc2
ELKS/RAB6-interacting/CAST family member 2
chr17_+_8283762 3.585 ENSMUST00000155364.1
ENSMUST00000046754.8
ENSMUST00000124023.1
Mpc1


mitochondrial pyruvate carrier 1


chr11_-_62457772 3.469 ENSMUST00000127471.2
Ncor1
nuclear receptor co-repressor 1
chr11_-_115627948 3.365 ENSMUST00000154623.1
ENSMUST00000106503.3
ENSMUST00000141614.1
Slc25a19


solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19


chr11_-_95309557 3.236 ENSMUST00000092766.5
ENSMUST00000072621.5
Kat7

K(lysine) acetyltransferase 7

chr18_-_43393346 3.233 ENSMUST00000025379.7
Dpysl3
dihydropyrimidinase-like 3
chr9_-_55919605 3.215 ENSMUST00000037408.8
Scaper
S phase cyclin A-associated protein in the ER
chr18_+_69346143 3.084 ENSMUST00000114980.1
Tcf4
transcription factor 4
chr11_-_115628125 3.045 ENSMUST00000155709.1
ENSMUST00000021089.4
Slc25a19

solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19

chr11_-_115628260 2.983 ENSMUST00000178003.1
Slc25a19
solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
chr13_-_54749849 2.956 ENSMUST00000135343.1
Gprin1
G protein-regulated inducer of neurite outgrowth 1
chr6_+_96115249 2.879 ENSMUST00000075080.5
Fam19a1
family with sequence similarity 19, member A1
chr7_+_4460687 2.866 ENSMUST00000167298.1
ENSMUST00000171445.1
Eps8l1

EPS8-like 1

chrX_+_41401128 2.820 ENSMUST00000115103.2
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr15_-_101850778 2.805 ENSMUST00000023790.3
Krt1
keratin 1
chr1_-_189922338 2.802 ENSMUST00000027897.7
Smyd2
SET and MYND domain containing 2
chr13_+_109685994 2.649 ENSMUST00000074103.5
Pde4d
phosphodiesterase 4D, cAMP specific
chrX_+_41401304 2.574 ENSMUST00000076349.5
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr16_-_74411776 2.556 ENSMUST00000116586.2
Robo2
roundabout homolog 2 (Drosophila)
chr4_+_102741287 2.237 ENSMUST00000097948.2
Sgip1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr7_-_73537621 2.019 ENSMUST00000172704.1
Chd2
chromodomain helicase DNA binding protein 2
chr6_-_118455475 1.914 ENSMUST00000161519.1
ENSMUST00000069292.7
Zfp248

zinc finger protein 248

chr8_+_25720054 1.904 ENSMUST00000068916.8
ENSMUST00000139836.1
Ppapdc1b

phosphatidic acid phosphatase type 2 domain containing 1B

chr1_-_93101825 1.788 ENSMUST00000112958.2
Kif1a
kinesin family member 1A
chr4_-_129378116 1.758 ENSMUST00000030610.2
Zbtb8a
zinc finger and BTB domain containing 8a
chr13_-_12464925 1.749 ENSMUST00000124888.1
Lgals8
lectin, galactose binding, soluble 8
chr12_+_78226627 1.749 ENSMUST00000110388.2
ENSMUST00000052472.4
Gphn

gephyrin

chr18_+_37655891 1.705 ENSMUST00000097608.2
3222401L13Rik
RIKEN cDNA 3222401L13 gene
chr4_+_130913120 1.656 ENSMUST00000151698.1
Laptm5
lysosomal-associated protein transmembrane 5
chr16_+_75592844 1.610 ENSMUST00000114249.1
ENSMUST00000046378.7
ENSMUST00000114253.1
Rbm11


RNA binding motif protein 11


chr2_+_28205648 1.563 ENSMUST00000102879.3
ENSMUST00000028177.4
Olfm1

olfactomedin 1

chr6_-_55681257 1.442 ENSMUST00000044767.8
Neurod6
neurogenic differentiation 6
chr3_+_129532386 1.408 ENSMUST00000071402.2
Elovl6
ELOVL family member 6, elongation of long chain fatty acids (yeast)
chr18_+_37333853 1.402 ENSMUST00000061717.2
Pcdhb6
protocadherin beta 6
chr2_-_180824596 1.372 ENSMUST00000148700.1
Gm14340
predicted gene 14340
chr4_+_130913264 1.372 ENSMUST00000156225.1
ENSMUST00000156742.1
Laptm5

lysosomal-associated protein transmembrane 5

chr8_+_104250925 1.360 ENSMUST00000098464.4
Cklf
chemokine-like factor
chr4_+_108328136 1.354 ENSMUST00000131656.1
Selrc1
Sel1 repeat containing 1
chr2_-_120970706 1.347 ENSMUST00000028728.5
Ubr1
ubiquitin protein ligase E3 component n-recognin 1
chr10_+_90071095 1.338 ENSMUST00000183109.1
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr12_-_27160311 1.286 ENSMUST00000182473.1
ENSMUST00000177636.1
ENSMUST00000183238.1
Gm9866


predicted gene 9866


chr17_+_22361453 1.271 ENSMUST00000149699.1
ENSMUST00000088765.2
ENSMUST00000072477.4
ENSMUST00000121315.1
Zfp758



zinc finger protein 758



chr3_-_88458876 1.232 ENSMUST00000147200.1
ENSMUST00000169222.1
Sema4a

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A

chr19_+_58943413 1.221 ENSMUST00000054280.6
Eno4
enolase 4
chr8_+_31150307 1.207 ENSMUST00000098842.2
Tti2
TELO2 interacting protein 2
chr13_+_98263242 1.176 ENSMUST00000022164.8
ENSMUST00000150352.1
Ankra2

ankyrin repeat, family A (RFXANK-like), 2

chr11_+_77216180 1.157 ENSMUST00000037912.5
ENSMUST00000156488.1
Ssh2

slingshot homolog 2 (Drosophila)

chr13_+_98263187 1.151 ENSMUST00000091356.3
ENSMUST00000123924.1
Ankra2

ankyrin repeat, family A (RFXANK-like), 2

chr13_+_98263105 1.141 ENSMUST00000150916.1
Ankra2
ankyrin repeat, family A (RFXANK-like), 2
chr13_-_66851513 1.061 ENSMUST00000169322.1
Gm17404
predicted gene, 17404
chr3_-_88459047 1.051 ENSMUST00000165898.1
ENSMUST00000127436.1
Sema4a

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A

chr5_-_73256555 1.050 ENSMUST00000101127.5
ENSMUST00000171179.1
Fryl
Fryl
furry homolog-like (Drosophila)
furry homolog-like (Drosophila)
chr13_-_99344652 1.040 ENSMUST00000022153.6
Ptcd2
pentatricopeptide repeat domain 2
chr16_+_23224724 1.023 ENSMUST00000023601.7
St6gal1
beta galactoside alpha 2,6 sialyltransferase 1
chr15_-_77970750 0.987 ENSMUST00000100484.4
Eif3d
eukaryotic translation initiation factor 3, subunit D
chr16_+_87354185 0.983 ENSMUST00000054442.4
ENSMUST00000118310.1
ENSMUST00000120284.1
ENSMUST00000118115.1
N6amt1



N-6 adenine-specific DNA methyltransferase 1 (putative)



chr6_-_29216277 0.960 ENSMUST00000162215.1
Impdh1
inosine 5'-phosphate dehydrogenase 1
chr6_+_40325471 0.954 ENSMUST00000031977.8
Agk
acylglycerol kinase
chr11_-_62789402 0.945 ENSMUST00000108705.1
Zfp286
zinc finger protein 286
chr2_-_104712122 0.911 ENSMUST00000111118.1
ENSMUST00000028597.3
Tcp11l1

t-complex 11 like 1

chr8_+_40307458 0.882 ENSMUST00000068999.7
Micu3
mitochondrial calcium uptake family, member 3
chr14_-_104522615 0.874 ENSMUST00000022716.2
Rnf219
ring finger protein 219
chr11_-_62789445 0.856 ENSMUST00000054654.6
Zfp286
zinc finger protein 286
chr11_+_82045705 0.851 ENSMUST00000021011.2
Ccl7
chemokine (C-C motif) ligand 7
chr6_-_87809757 0.850 ENSMUST00000032134.7
Rab43
RAB43, member RAS oncogene family
chr3_+_32436376 0.846 ENSMUST00000108242.1
Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr6_-_29216301 0.812 ENSMUST00000162739.1
ENSMUST00000162099.1
ENSMUST00000159124.1
Impdh1


inosine 5'-phosphate dehydrogenase 1


chrX_+_20364481 0.774 ENSMUST00000033372.6
ENSMUST00000115391.1
ENSMUST00000115387.1
Rp2h


retinitis pigmentosa 2 homolog (human)


chr8_-_69625503 0.758 ENSMUST00000121886.1
Zfp868
zinc finger protein 868
chr12_-_20900867 0.731 ENSMUST00000079237.5
Zfp125
zinc finger protein 125
chr12_-_23780265 0.727 ENSMUST00000072014.4
Gm10330
predicted gene 10330
chr2_+_166805506 0.695 ENSMUST00000099078.3
Arfgef2
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr19_-_7483212 0.672 ENSMUST00000088169.5
Rtn3
reticulon 3
chr3_+_79885930 0.657 ENSMUST00000029567.8
Fam198b
family with sequence similarity 198, member B
chr11_-_30986326 0.644 ENSMUST00000020553.4
ENSMUST00000101394.4
Chac2

ChaC, cation transport regulator 2

chr2_+_23068168 0.611 ENSMUST00000028121.7
ENSMUST00000114523.2
ENSMUST00000144088.1
Acbd5


acyl-Coenzyme A binding domain containing 5


chr10_-_120979327 0.607 ENSMUST00000119944.1
ENSMUST00000119093.1
Lemd3

LEM domain containing 3

chr5_-_143292356 0.583 ENSMUST00000180336.1
Zfp853
zinc finger protein 853
chr8_+_105225145 0.571 ENSMUST00000034361.3
D230025D16Rik
RIKEN cDNA D230025D16 gene
chrX_-_165004829 0.569 ENSMUST00000114890.2
Gm17604
predicted gene, 17604
chr14_+_49172202 0.560 ENSMUST00000153488.1
Naa30
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr13_-_66852017 0.533 ENSMUST00000059329.6
Gm17449
predicted gene, 17449
chr18_-_38209762 0.521 ENSMUST00000057185.6
Pcdh1
protocadherin 1
chr6_+_42286709 0.481 ENSMUST00000163936.1
Clcn1
chloride channel 1
chr6_+_91878034 0.472 ENSMUST00000037783.5
Ccdc174
coiled-coil domain containing 174
chr7_+_126649297 0.455 ENSMUST00000032956.8
Ccdc101
coiled-coil domain containing 101
chr11_+_55213783 0.450 ENSMUST00000108867.1
Slc36a1
solute carrier family 36 (proton/amino acid symporter), member 1
chr5_-_123666682 0.421 ENSMUST00000149410.1
Clip1
CAP-GLY domain containing linker protein 1
chr16_-_23225334 0.419 ENSMUST00000055369.4
BC106179
cDNA sequence BC106179
chr19_-_46338632 0.416 ENSMUST00000051234.8
ENSMUST00000167861.1
Cuedc2

CUE domain containing 2

chr5_-_116024475 0.363 ENSMUST00000111999.1
Prkab1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr11_-_72267141 0.363 ENSMUST00000137701.1
Slc13a5
solute carrier family 13 (sodium-dependent citrate transporter), member 5
chr5_-_20951769 0.351 ENSMUST00000036489.5
Rsbn1l
round spermatid basic protein 1-like
chr12_+_59066908 0.304 ENSMUST00000021381.4
Pnn
pinin
chr11_+_3963970 0.295 ENSMUST00000020705.4
ENSMUST00000109985.1
Pes1

pescadillo homolog 1, containing BRCT domain (zebrafish)

chr16_+_96235801 0.272 ENSMUST00000113800.2
B3galt5
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5
chr8_+_124023394 0.271 ENSMUST00000034457.8
Urb2
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr17_-_24455265 0.241 ENSMUST00000056032.7
E4f1
E4F transcription factor 1
chr19_-_7341848 0.240 ENSMUST00000171393.1
Mark2
MAP/microtubule affinity-regulating kinase 2
chr7_-_126649556 0.237 ENSMUST00000084587.1
2510046G10Rik
RIKEN cDNA 2510046G10 gene
chr13_-_98262946 0.229 ENSMUST00000040972.2
Utp15
UTP15, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr6_+_42286676 0.225 ENSMUST00000031894.6
Clcn1
chloride channel 1
chr7_-_141435327 0.217 ENSMUST00000138865.1
Slc25a22
solute carrier family 25 (mitochondrial carrier, glutamate), member 22
chr13_+_58281183 0.196 ENSMUST00000180882.1
ENSMUST00000180452.1
Gm26555

predicted gene, 26555

chr15_+_85510812 0.134 ENSMUST00000079690.2
Gm4825
predicted pseudogene 4825
chr1_+_178529113 0.129 ENSMUST00000161017.1
Kif26b
kinesin family member 26B
chr9_-_44407526 0.121 ENSMUST00000034623.6
Trappc4
trafficking protein particle complex 4
chr4_-_45408646 0.120 ENSMUST00000153904.1
ENSMUST00000132815.2
ENSMUST00000107796.1
ENSMUST00000116341.3
Slc25a51



solute carrier family 25, member 51



chr3_+_89177463 0.102 ENSMUST00000029684.8
ENSMUST00000120697.1
ENSMUST00000098941.4
Scamp3


secretory carrier membrane protein 3


chr14_-_34503323 0.092 ENSMUST00000171343.1
Bmpr1a
bone morphogenetic protein receptor, type 1A
chr11_-_5542177 0.092 ENSMUST00000020776.4
Ccdc117
coiled-coil domain containing 117
chr11_-_23895208 0.058 ENSMUST00000102863.2
ENSMUST00000020513.3
Papolg

poly(A) polymerase gamma

chr18_-_46280820 0.049 ENSMUST00000025354.3
Pggt1b
protein geranylgeranyltransferase type I, beta subunit
chr15_-_100424092 0.041 ENSMUST00000154676.1
Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr11_+_75732869 0.033 ENSMUST00000067664.3
Ywhae
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr7_-_141434532 0.033 ENSMUST00000133021.1
ENSMUST00000106007.3
ENSMUST00000150026.1
ENSMUST00000133206.2
Slc25a22



solute carrier family 25 (mitochondrial carrier, glutamate), member 22



chr5_-_116024452 0.015 ENSMUST00000031486.7
Prkab1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr9_-_106247730 0.014 ENSMUST00000112524.2
ENSMUST00000074082.6
Alas1

aminolevulinic acid synthase 1

chrX_+_74270812 0.010 ENSMUST00000008826.7
ENSMUST00000151702.1
ENSMUST00000074085.5
ENSMUST00000135690.1
Rpl10



ribosomal protein L10




Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 9.4 GO:0030974 thiamine pyrophosphate transport(GO:0030974)
1.9 9.4 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
1.8 5.3 GO:0043031 negative regulation of macrophage activation(GO:0043031)
1.7 10.4 GO:0042045 epithelial fluid transport(GO:0042045)
1.1 6.9 GO:0009405 pathogenesis(GO:0009405)
1.1 3.2 GO:0072720 response to sorbitol(GO:0072708) response to dithiothreitol(GO:0072720)
0.9 3.6 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.9 7.1 GO:0070314 G1 to G0 transition(GO:0070314)
0.9 3.5 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.9 2.6 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.8 13.1 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.7 5.2 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.5 13.5 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
0.4 2.9 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.4 2.8 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.4 1.8 GO:0006177 GMP biosynthetic process(GO:0006177)
0.4 2.8 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.3 1.7 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.3 1.3 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.3 1.0 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.3 1.7 GO:0002317 plasma cell differentiation(GO:0002317)
0.3 0.9 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.3 0.8 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.3 3.1 GO:0042118 endothelial cell activation(GO:0042118)
0.3 1.0 GO:2000110 protein sialylation(GO:1990743) negative regulation of macrophage apoptotic process(GO:2000110)
0.2 2.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.2 2.6 GO:1901898 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 8.6 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.2 3.2 GO:0051764 actin crosslink formation(GO:0051764)
0.2 0.6 GO:0006751 glutathione catabolic process(GO:0006751)
0.1 1.0 GO:0090527 actin filament reorganization(GO:0090527)
0.1 2.0 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.1 1.6 GO:0023041 neuronal signal transduction(GO:0023041)
0.1 1.4 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 1.8 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 0.6 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 5.4 GO:0001919 regulation of receptor recycling(GO:0001919)
0.1 0.7 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 1.3 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 2.3 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.1 0.9 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 0.4 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 0.4 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.1 0.4 GO:0015744 succinate transport(GO:0015744)
0.1 0.6 GO:0030242 pexophagy(GO:0030242)
0.1 0.6 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 1.4 GO:0021542 dentate gyrus development(GO:0021542)
0.1 5.2 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.1 0.7 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.5 GO:0015808 L-alanine transport(GO:0015808)
0.1 0.7 GO:0001881 receptor recycling(GO:0001881)
0.1 0.4 GO:0035878 nail development(GO:0035878)
0.0 0.1 GO:0072092 ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093)
0.0 0.2 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0 1.4 GO:0009988 cell-cell recognition(GO:0009988)
0.0 1.4 GO:0048246 macrophage chemotaxis(GO:0048246)
0.0 0.2 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.9 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 1.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.2 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.3 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.1 GO:0021998 neural plate mediolateral regionalization(GO:0021998) mesoderm structural organization(GO:0048338) paraxial mesoderm structural organization(GO:0048352) positive regulation of cardiac ventricle development(GO:1904414)
0.0 1.0 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 0.0 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 1.2 GO:0030317 sperm motility(GO:0030317)
0.0 4.6 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 4.6 GO:0016236 macroautophagy(GO:0016236)
0.0 0.1 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.0 1.0 GO:0048747 muscle fiber development(GO:0048747)
0.0 0.6 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 3.5 GO:0043254 regulation of protein complex assembly(GO:0043254)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 10.4 GO:0031088 platelet dense granule membrane(GO:0031088)
3.1 9.4 GO:0043512 inhibin A complex(GO:0043512)
0.6 8.6 GO:0042581 specific granule(GO:0042581)
0.6 3.5 GO:1990393 3M complex(GO:1990393)
0.6 2.8 GO:0001533 cornified envelope(GO:0001533)
0.4 7.1 GO:0031045 dense core granule(GO:0031045)
0.4 13.0 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.4 5.4 GO:0043083 synaptic cleft(GO:0043083)
0.3 0.8 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.2 0.6 GO:0031417 NatC complex(GO:0031417)
0.2 0.7 GO:0032280 symmetric synapse(GO:0032280)
0.2 3.5 GO:0016580 Sin3 complex(GO:0016580)
0.2 13.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 2.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 1.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 1.0 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 1.0 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 4.1 GO:0048786 presynaptic active zone(GO:0048786)
0.1 1.7 GO:0060077 inhibitory synapse(GO:0060077)
0.1 2.6 GO:0030673 axolemma(GO:0030673)
0.1 2.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 0.4 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 3.2 GO:0031941 filamentous actin(GO:0031941)
0.0 5.3 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.6 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 3.2 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 0.3 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 2.1 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.7 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.9 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 2.5 GO:0008021 synaptic vesicle(GO:0008021)
0.0 1.3 GO:0000502 proteasome complex(GO:0000502)
0.0 2.9 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 3.4 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 1.4 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.5 13.5 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
3.5 10.4 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
1.6 9.4 GO:0070699 type II activin receptor binding(GO:0070699)
1.6 9.4 GO:0015234 thiamine transmembrane transporter activity(GO:0015234)
0.9 3.6 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.8 3.1 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.8 5.4 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.5 6.9 GO:0015643 toxic substance binding(GO:0015643)
0.5 2.8 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.4 1.8 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.4 1.7 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.4 3.5 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.4 3.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.3 1.0 GO:0001729 ceramide kinase activity(GO:0001729)
0.3 2.6 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 3.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 1.3 GO:0070728 leucine binding(GO:0070728)
0.2 0.9 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.2 1.0 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.2 5.2 GO:0043539 insulin-like growth factor receptor binding(GO:0005159) protein serine/threonine kinase activator activity(GO:0043539)
0.2 0.5 GO:0015173 hydrogen:amino acid symporter activity(GO:0005280) aromatic amino acid transmembrane transporter activity(GO:0015173)
0.1 2.9 GO:0042608 T cell receptor binding(GO:0042608)
0.1 1.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.6 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 1.4 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.4 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.1 0.8 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 3.5 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 2.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 1.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 1.0 GO:0000339 RNA cap binding(GO:0000339)
0.0 1.4 GO:0008009 chemokine activity(GO:0008009)
0.0 0.7 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.4 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.6 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 1.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 4.7 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 15.0 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 1.2 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.2 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 3.4 GO:0008017 microtubule binding(GO:0008017)
0.0 2.5 GO:0030246 carbohydrate binding(GO:0030246)
0.0 1.0 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 2.0 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 0.0 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 7.0 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.2 9.4 PID_ALK1_PATHWAY ALK1 signaling events
0.1 5.2 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 4.3 PID_ERBB4_PATHWAY ErbB4 signaling events
0.1 3.5 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.1 5.9 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 3.2 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 4.0 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 9.4 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.3 5.2 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 5.4 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.2 3.2 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.8 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 3.5 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 1.0 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 2.3 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.1 3.1 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 2.6 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.1 2.6 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.1 1.4 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.4 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.8 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.9 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 1.7 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.7 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.5 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane