Motif ID: Hoxa13

Z-value: 0.755


Transcription factors associated with Hoxa13:

Gene SymbolEntrez IDGene Name
Hoxa13 ENSMUSG00000038203.12 Hoxa13



Activity profile for motif Hoxa13.

activity profile for motif Hoxa13


Sorted Z-values histogram for motif Hoxa13

Sorted Z-values for motif Hoxa13



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa13

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrY_-_1286563 5.357 ENSMUST00000091190.5
Ddx3y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr14_+_65805832 5.008 ENSMUST00000022612.3
Pbk
PDZ binding kinase
chr17_+_75178797 4.584 ENSMUST00000112516.1
ENSMUST00000135447.1
Ltbp1

latent transforming growth factor beta binding protein 1

chr14_+_65806066 4.437 ENSMUST00000139644.1
Pbk
PDZ binding kinase
chr4_-_133967296 4.242 ENSMUST00000105893.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr2_-_129297205 4.159 ENSMUST00000052708.6
Ckap2l
cytoskeleton associated protein 2-like
chr17_+_75178911 4.143 ENSMUST00000112514.1
Ltbp1
latent transforming growth factor beta binding protein 1
chr1_-_45503282 4.110 ENSMUST00000086430.4
Col5a2
collagen, type V, alpha 2
chrX_+_106920618 4.068 ENSMUST00000060576.7
Lpar4
lysophosphatidic acid receptor 4
chr14_-_47411666 3.990 ENSMUST00000111778.3
Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chrX_+_141475385 3.582 ENSMUST00000112931.1
ENSMUST00000112930.1
Col4a5

collagen, type IV, alpha 5

chr11_-_84067063 3.504 ENSMUST00000108101.1
Dusp14
dual specificity phosphatase 14
chr4_-_154636831 3.260 ENSMUST00000030902.6
ENSMUST00000105637.1
ENSMUST00000070313.7
ENSMUST00000105636.1
ENSMUST00000105638.2
ENSMUST00000097759.2
ENSMUST00000124771.1
Prdm16






PR domain containing 16






chr3_-_88410295 3.252 ENSMUST00000056370.7
Pmf1
polyamine-modulated factor 1
chr15_+_25773985 3.251 ENSMUST00000125667.1
Myo10
myosin X
chr8_-_4779513 3.107 ENSMUST00000022945.7
Shcbp1
Shc SH2-domain binding protein 1
chr9_+_65890237 3.102 ENSMUST00000045802.6
2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr4_+_144893127 3.060 ENSMUST00000142808.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr2_-_18048784 2.993 ENSMUST00000142856.1
Skida1
SKI/DACH domain containing 1
chr18_-_78206408 2.974 ENSMUST00000163367.1
Slc14a2
solute carrier family 14 (urea transporter), member 2
chr19_-_5796924 2.882 ENSMUST00000174808.1
Malat1
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chr5_+_92809372 2.815 ENSMUST00000113054.2
Shroom3
shroom family member 3
chr5_-_62766153 2.786 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr10_-_116972609 2.784 ENSMUST00000092165.4
Gm10271
predicted gene 10271
chrX_-_109013389 2.705 ENSMUST00000033597.8
Hmgn5
high-mobility group nucleosome binding domain 5
chr16_-_18811972 2.663 ENSMUST00000000028.7
ENSMUST00000115585.1
Cdc45

cell division cycle 45

chr5_+_64812336 2.657 ENSMUST00000166409.1
Klf3
Kruppel-like factor 3 (basic)
chrY_+_897782 2.595 ENSMUST00000055032.7
Kdm5d
lysine (K)-specific demethylase 5D
chr13_-_23430826 2.559 ENSMUST00000153753.1
ENSMUST00000141543.1
C230035I16Rik

RIKEN cDNA C230035I16 gene

chr12_-_54986363 2.554 ENSMUST00000173433.1
ENSMUST00000173803.1
Baz1a
Gm20403
bromodomain adjacent to zinc finger domain 1A
predicted gene 20403
chr3_-_49757257 2.519 ENSMUST00000035931.7
Pcdh18
protocadherin 18
chr10_-_13324160 2.486 ENSMUST00000105545.4
Phactr2
phosphatase and actin regulator 2
chr12_-_54986328 2.481 ENSMUST00000038926.6
Baz1a
bromodomain adjacent to zinc finger domain 1A
chr8_+_94179089 2.450 ENSMUST00000034215.6
Mt1
metallothionein 1
chr7_+_4119556 2.419 ENSMUST00000079415.5
Ttyh1
tweety homolog 1 (Drosophila)
chr11_+_108587077 2.404 ENSMUST00000146912.2
Cep112
centrosomal protein 112
chr7_+_4119525 2.376 ENSMUST00000119661.1
ENSMUST00000129423.1
Ttyh1

tweety homolog 1 (Drosophila)

chr7_-_37772868 2.363 ENSMUST00000176205.1
Zfp536
zinc finger protein 536
chr7_+_127800604 2.358 ENSMUST00000046863.5
ENSMUST00000106272.1
ENSMUST00000139068.1
Hsd3b7


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7


chr19_+_34922351 2.328 ENSMUST00000087341.5
Kif20b
kinesin family member 20B
chr12_+_79297345 2.271 ENSMUST00000079533.5
ENSMUST00000171210.1
Rad51b

RAD51 homolog B

chr13_-_64312676 2.255 ENSMUST00000021938.9
Aaed1
AhpC/TSA antioxidant enzyme domain containing 1
chr17_+_57249450 2.231 ENSMUST00000019631.9
Trip10
thyroid hormone receptor interactor 10
chr2_+_126215100 2.223 ENSMUST00000164042.2
Gm17555
predicted gene, 17555
chr9_-_54661870 2.179 ENSMUST00000034822.5
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr4_-_110290884 2.171 ENSMUST00000142722.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr5_+_137641334 2.168 ENSMUST00000177466.1
ENSMUST00000166099.2
Sap25

sin3 associated polypeptide

chr14_+_28511344 2.161 ENSMUST00000112272.1
Wnt5a
wingless-related MMTV integration site 5A
chr2_-_18048347 2.145 ENSMUST00000066885.5
Skida1
SKI/DACH domain containing 1
chr6_-_125494754 2.144 ENSMUST00000032492.8
Cd9
CD9 antigen
chr2_-_33942111 2.072 ENSMUST00000130988.1
ENSMUST00000127936.1
ENSMUST00000134271.1
Gm13403


predicted gene 13403


chr2_+_158768083 1.994 ENSMUST00000029183.2
Fam83d
family with sequence similarity 83, member D
chr10_-_105574435 1.980 ENSMUST00000061506.8
Tmtc2
transmembrane and tetratricopeptide repeat containing 2
chr2_+_35132194 1.972 ENSMUST00000113034.1
ENSMUST00000113037.3
ENSMUST00000113033.2
Cep110


centrosomal protein 110


chr11_+_97029925 1.960 ENSMUST00000021249.4
Scrn2
secernin 2
chr11_+_70657196 1.898 ENSMUST00000157027.1
ENSMUST00000072841.5
ENSMUST00000108548.1
ENSMUST00000126241.1
Eno3



enolase 3, beta muscle



chr16_+_15317458 1.885 ENSMUST00000178312.1
Gm21897
predicted gene, 21897
chr17_+_56303321 1.876 ENSMUST00000001258.8
Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
chr2_-_63184253 1.875 ENSMUST00000075052.3
ENSMUST00000112454.1
Kcnh7

potassium voltage-gated channel, subfamily H (eag-related), member 7

chr19_+_44493472 1.860 ENSMUST00000041163.4
Wnt8b
wingless related MMTV integration site 8b
chr6_+_125215551 1.848 ENSMUST00000032487.7
ENSMUST00000100942.2
ENSMUST00000063588.8
Vamp1


vesicle-associated membrane protein 1


chr10_+_25408346 1.848 ENSMUST00000092645.6
Epb4.1l2
erythrocyte protein band 4.1-like 2
chr3_+_137671524 1.824 ENSMUST00000166899.2
Gm21962
predicted gene, 21962
chr16_+_82828382 1.819 ENSMUST00000177665.1
Gm21833
predicted gene, 21833
chr11_-_70656467 1.813 ENSMUST00000131642.1
Gm12319
predicted gene 12319
chr1_-_138847579 1.808 ENSMUST00000093486.3
ENSMUST00000046870.6
Lhx9

LIM homeobox protein 9

chr10_+_93641041 1.790 ENSMUST00000020204.4
Ntn4
netrin 4
chrM_+_11734 1.789 ENSMUST00000082418.1
mt-Nd5
mitochondrially encoded NADH dehydrogenase 5
chr14_+_73661225 1.785 ENSMUST00000098874.3
Gm21750
predicted gene, 21750
chr4_-_3938354 1.781 ENSMUST00000003369.3
Plag1
pleiomorphic adenoma gene 1
chr3_+_5218546 1.777 ENSMUST00000026284.6
Zfhx4
zinc finger homeodomain 4
chr6_+_120666388 1.775 ENSMUST00000112686.1
Cecr2
cat eye syndrome chromosome region, candidate 2
chr1_+_146420434 1.728 ENSMUST00000163646.1
Gm5263
predicted gene 5263
chr7_+_30565410 1.705 ENSMUST00000043850.7
Igflr1
IGF-like family receptor 1
chr11_-_109473220 1.669 ENSMUST00000070872.6
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr4_-_82850721 1.663 ENSMUST00000139401.1
Zdhhc21
zinc finger, DHHC domain containing 21
chr12_+_112620030 1.652 ENSMUST00000180015.1
ENSMUST00000021726.6
Adssl1

adenylosuccinate synthetase like 1

chr17_+_56303396 1.651 ENSMUST00000113038.1
Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
chr9_+_58134017 1.638 ENSMUST00000134955.1
ENSMUST00000147134.1
ENSMUST00000170397.1
Stra6


stimulated by retinoic acid gene 6


chr12_+_59129720 1.636 ENSMUST00000175912.1
ENSMUST00000176892.1
Ctage5

CTAGE family, member 5

chr9_-_114781986 1.614 ENSMUST00000035009.8
ENSMUST00000084867.7
Cmtm7

CKLF-like MARVEL transmembrane domain containing 7

chr12_+_59129757 1.605 ENSMUST00000069430.8
ENSMUST00000177370.1
Ctage5

CTAGE family, member 5

chrX_+_82948861 1.590 ENSMUST00000114000.1
Dmd
dystrophin, muscular dystrophy
chr13_-_23622502 1.588 ENSMUST00000062045.2
Hist1h1e
histone cluster 1, H1e
chr6_+_29694204 1.551 ENSMUST00000046750.7
ENSMUST00000115250.3
Tspan33

tetraspanin 33

chr17_-_25844417 1.543 ENSMUST00000176591.1
Rhot2
ras homolog gene family, member T2
chr5_+_110839973 1.541 ENSMUST00000066160.1
Chek2
checkpoint kinase 2
chr4_-_133967235 1.525 ENSMUST00000123234.1
Hmgn2
high mobility group nucleosomal binding domain 2
chr1_+_61638819 1.484 ENSMUST00000138768.1
ENSMUST00000075374.3
Pard3b

par-3 partitioning defective 3 homolog B (C. elegans)

chr9_+_35423582 1.482 ENSMUST00000154652.1
Cdon
cell adhesion molecule-related/down-regulated by oncogenes
chr9_-_62510498 1.470 ENSMUST00000164246.2
Coro2b
coronin, actin binding protein, 2B
chr1_+_173420567 1.464 ENSMUST00000173023.1
Aim2
absent in melanoma 2
chrM_-_14060 1.452 ENSMUST00000082419.1
mt-Nd6
mitochondrially encoded NADH dehydrogenase 6
chr4_-_92191749 1.431 ENSMUST00000123179.1
Gm12666
predicted gene 12666
chr17_-_26095487 1.397 ENSMUST00000025007.5
Nme4
NME/NM23 nucleoside diphosphate kinase 4
chr7_-_44670820 1.396 ENSMUST00000048102.7
Myh14
myosin, heavy polypeptide 14
chr4_+_41762309 1.393 ENSMUST00000108042.2
Il11ra1
interleukin 11 receptor, alpha chain 1
chr8_+_95352258 1.375 ENSMUST00000034243.5
Mmp15
matrix metallopeptidase 15
chr4_-_42661893 1.326 ENSMUST00000108006.3
Il11ra2
interleukin 11 receptor, alpha chain 2
chr2_+_124089961 1.318 ENSMUST00000103241.1
Sema6d
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr5_-_25705791 1.253 ENSMUST00000030773.7
Xrcc2
X-ray repair complementing defective repair in Chinese hamster cells 2
chr10_-_49783259 1.249 ENSMUST00000105484.3
ENSMUST00000105486.1
ENSMUST00000079751.2
ENSMUST00000105485.1
Grik2



glutamate receptor, ionotropic, kainate 2 (beta 2)



chr4_+_105157339 1.249 ENSMUST00000064139.7
Ppap2b
phosphatidic acid phosphatase type 2B
chr9_-_64022043 1.248 ENSMUST00000041029.5
Smad6
SMAD family member 6
chr1_-_173942445 1.226 ENSMUST00000042228.8
ENSMUST00000081216.5
ENSMUST00000129829.1
ENSMUST00000123708.1
ENSMUST00000111210.2
Ifi203



Mndal
interferon activated gene 203



myeloid nuclear differentiation antigen like
chr4_-_116994374 1.213 ENSMUST00000030446.8
Urod
uroporphyrinogen decarboxylase
chr17_+_78491549 1.213 ENSMUST00000079363.4
Gm10093
predicted pseudogene 10093
chr3_+_5218516 1.205 ENSMUST00000175866.1
Zfhx4
zinc finger homeodomain 4
chr19_-_50678642 1.201 ENSMUST00000072685.6
ENSMUST00000164039.2
Sorcs1

VPS10 domain receptor protein SORCS 1

chr4_+_133130505 1.166 ENSMUST00000084241.5
ENSMUST00000138831.1
Wasf2

WAS protein family, member 2

chr5_-_120472763 1.164 ENSMUST00000052258.7
ENSMUST00000031594.6
Sdsl

serine dehydratase-like

chr15_+_9436028 1.158 ENSMUST00000042360.3
Capsl
calcyphosine-like
chr6_-_120357422 1.156 ENSMUST00000032283.5
Ccdc77
coiled-coil domain containing 77
chr6_-_56362356 1.151 ENSMUST00000044505.7
ENSMUST00000166102.1
ENSMUST00000164037.1
ENSMUST00000114327.2
Pde1c



phosphodiesterase 1C



chr1_+_82339049 1.148 ENSMUST00000140020.1
Rhbdd1
rhomboid domain containing 1
chr2_-_63184170 1.144 ENSMUST00000112452.1
Kcnh7
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr15_+_31224371 1.139 ENSMUST00000044524.9
Dap
death-associated protein
chrM_+_3906 1.127 ENSMUST00000082396.1
mt-Nd2
mitochondrially encoded NADH dehydrogenase 2
chr1_-_105659008 1.114 ENSMUST00000070699.8
Pign
phosphatidylinositol glycan anchor biosynthesis, class N
chr6_-_120357440 1.109 ENSMUST00000112703.1
Ccdc77
coiled-coil domain containing 77
chr4_-_81442756 1.108 ENSMUST00000107262.1
ENSMUST00000102830.3
Mpdz

multiple PDZ domain protein

chr3_+_66985680 1.098 ENSMUST00000065047.6
Rsrc1
arginine/serine-rich coiled-coil 1
chr4_-_94556737 1.096 ENSMUST00000030313.8
Caap1
caspase activity and apoptosis inhibitor 1
chr11_-_109472611 1.086 ENSMUST00000168740.1
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr7_-_41499890 1.084 ENSMUST00000098509.3
AW146154
expressed sequence AW146154
chr1_-_172027269 1.079 ENSMUST00000027837.6
ENSMUST00000111264.1
Vangl2

vang-like 2 (van gogh, Drosophila)

chr18_+_69593361 1.078 ENSMUST00000114978.2
ENSMUST00000114977.1
Tcf4

transcription factor 4

chr2_-_73485733 1.074 ENSMUST00000102680.1
Wipf1
WAS/WASL interacting protein family, member 1
chr3_+_5218589 1.068 ENSMUST00000177488.1
Zfhx4
zinc finger homeodomain 4
chr2_+_3424123 1.064 ENSMUST00000061852.5
ENSMUST00000100463.3
ENSMUST00000102988.3
ENSMUST00000115066.1
Dclre1c



DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae)



chr16_+_91225550 1.058 ENSMUST00000035608.8
Olig2
oligodendrocyte transcription factor 2
chr7_+_41599250 1.028 ENSMUST00000163475.1
2610021A01Rik
RIKEN cDNA 2610021A01 gene
chr17_-_25844514 1.023 ENSMUST00000176709.1
Rhot2
ras homolog gene family, member T2
chr7_+_103550368 0.997 ENSMUST00000106888.1
Olfr613
olfactory receptor 613
chr8_-_45975224 0.979 ENSMUST00000095323.1
ENSMUST00000098786.2
1700029J07Rik

RIKEN cDNA 1700029J07 gene

chr4_-_116994354 0.976 ENSMUST00000130273.1
Urod
uroporphyrinogen decarboxylase
chr13_+_96082158 0.974 ENSMUST00000185178.1
Gm17190
predicted gene 17190
chr5_-_36830647 0.970 ENSMUST00000031002.3
Man2b2
mannosidase 2, alpha B2
chr3_+_54481429 0.960 ENSMUST00000091130.3
Gm5641
predicted gene 5641
chr4_+_110397661 0.958 ENSMUST00000106589.2
ENSMUST00000106587.2
ENSMUST00000106591.1
ENSMUST00000106592.1
Agbl4



ATP/GTP binding protein-like 4



chr7_+_119794102 0.957 ENSMUST00000084644.2
2610020H08Rik
RIKEN cDNA 2610020H08 gene
chr13_-_3893556 0.953 ENSMUST00000099946.4
Net1
neuroepithelial cell transforming gene 1
chrX_+_136741821 0.927 ENSMUST00000089350.4
BC065397
cDNA sequence BC065397
chr6_-_120357342 0.911 ENSMUST00000163827.1
Ccdc77
coiled-coil domain containing 77
chr5_+_64160207 0.911 ENSMUST00000101195.2
Tbc1d1
TBC1 domain family, member 1
chr17_-_35074485 0.907 ENSMUST00000007259.3
Ly6g6d
lymphocyte antigen 6 complex, locus G6D
chr4_-_133967893 0.900 ENSMUST00000100472.3
ENSMUST00000136327.1
Hmgn2

high mobility group nucleosomal binding domain 2

chr16_+_38562806 0.900 ENSMUST00000171687.1
ENSMUST00000002924.8
Tmem39a

transmembrane protein 39a

chr3_-_80802789 0.898 ENSMUST00000107745.1
ENSMUST00000075316.4
Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr16_+_97489994 0.896 ENSMUST00000177820.1
Gm9242
predicted pseudogene 9242
chr1_-_44218952 0.886 ENSMUST00000054801.3
Mettl21e
methyltransferase like 21E
chr14_-_77874887 0.874 ENSMUST00000022590.3
Dnajc15
DnaJ (Hsp40) homolog, subfamily C, member 15
chr16_+_43889896 0.873 ENSMUST00000122014.1
ENSMUST00000178400.1
2610015P09Rik

RIKEN cDNA 2610015P09 gene

chr4_+_148140699 0.856 ENSMUST00000140049.1
ENSMUST00000105707.1
Mad2l2

MAD2 mitotic arrest deficient-like 2

chr3_+_40540751 0.849 ENSMUST00000091186.3
Intu
inturned planar cell polarity effector homolog (Drosophila)
chr9_-_13245741 0.843 ENSMUST00000110582.2
Jrkl
jerky homolog-like (mouse)
chrX_-_7319186 0.832 ENSMUST00000115746.1
Clcn5
chloride channel 5
chr11_-_62392605 0.814 ENSMUST00000151498.2
ENSMUST00000159069.1
Ncor1

nuclear receptor co-repressor 1

chr1_+_58646608 0.806 ENSMUST00000081455.4
Gm10068
predicted gene 10068
chr8_+_129118043 0.802 ENSMUST00000108744.1
1700008F21Rik
RIKEN cDNA 1700008F21 gene
chr13_+_80883403 0.802 ENSMUST00000099356.2
Arrdc3
arrestin domain containing 3
chr4_+_110397764 0.800 ENSMUST00000097920.2
ENSMUST00000080744.6
Agbl4

ATP/GTP binding protein-like 4

chr13_-_55100248 0.798 ENSMUST00000026997.5
ENSMUST00000127195.1
ENSMUST00000099496.3
Uimc1


ubiquitin interaction motif containing 1


chr3_+_76074270 0.793 ENSMUST00000038364.8
Fstl5
follistatin-like 5
chr11_+_69914179 0.792 ENSMUST00000057884.5
Gps2
G protein pathway suppressor 2
chr12_+_80945500 0.789 ENSMUST00000094693.4
Srsf5
serine/arginine-rich splicing factor 5
chr4_-_97183166 0.788 ENSMUST00000086672.2
Gm10192
predicted gene 10192
chr16_+_43889800 0.778 ENSMUST00000132859.1
2610015P09Rik
RIKEN cDNA 2610015P09 gene
chr8_+_45507768 0.773 ENSMUST00000067065.7
ENSMUST00000098788.3
ENSMUST00000067107.7
ENSMUST00000171337.2
ENSMUST00000138049.1
ENSMUST00000141039.1
Sorbs2





sorbin and SH3 domain containing 2





chr2_-_118549668 0.770 ENSMUST00000090219.6
Bmf
BCL2 modifying factor
chrX_+_96455359 0.767 ENSMUST00000033553.7
Heph
hephaestin
chr13_+_24943144 0.765 ENSMUST00000021773.5
Gpld1
glycosylphosphatidylinositol specific phospholipase D1
chr10_-_13388830 0.752 ENSMUST00000079698.5
Phactr2
phosphatase and actin regulator 2
chr13_+_94083490 0.732 ENSMUST00000156071.1
Lhfpl2
lipoma HMGIC fusion partner-like 2
chr17_+_45433823 0.732 ENSMUST00000181149.1
B230354K17Rik
RIKEN cDNA B230354K17 gene
chr6_+_65042575 0.731 ENSMUST00000031984.6
Smarcad1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr3_-_116614587 0.719 ENSMUST00000041524.4
Trmt13
tRNA methyltransferase 13
chr8_+_46163651 0.717 ENSMUST00000034048.6
ENSMUST00000145229.1
4933411K20Rik

RIKEN cDNA 4933411K20 gene

chr7_+_44896077 0.715 ENSMUST00000071207.7
ENSMUST00000166849.1
ENSMUST00000168712.1
ENSMUST00000168389.1
Fuz



fuzzy homolog (Drosophila)



chr10_-_120112946 0.711 ENSMUST00000020449.5
Helb
helicase (DNA) B
chr19_+_56548254 0.696 ENSMUST00000071423.5
Nhlrc2
NHL repeat containing 2
chr4_-_133967953 0.693 ENSMUST00000102553.4
Hmgn2
high mobility group nucleosomal binding domain 2
chr2_+_104065826 0.691 ENSMUST00000104891.1
Gm10912
predicted gene 10912
chr1_+_139422196 0.690 ENSMUST00000039867.7
Zbtb41
zinc finger and BTB domain containing 41 homolog
chr5_-_16731074 0.688 ENSMUST00000073014.5
Gm8991
predicted pseudogene 8991
chr2_-_76673039 0.680 ENSMUST00000002809.7
Fkbp7
FK506 binding protein 7
chr1_-_97128249 0.679 ENSMUST00000027569.7
Slco6c1
solute carrier organic anion transporter family, member 6c1
chr6_+_15196949 0.677 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
Foxp2



forkhead box P2



chr1_-_175688353 0.676 ENSMUST00000104984.1
Chml
choroideremia-like
chr2_-_29787622 0.675 ENSMUST00000177467.1
ENSMUST00000113807.3
Trub2

TruB pseudouridine (psi) synthase homolog 2 (E. coli)

chr3_+_89266552 0.671 ENSMUST00000040824.1
Dpm3
dolichyl-phosphate mannosyltransferase polypeptide 3
chr16_+_38562821 0.666 ENSMUST00000163948.1
Tmem39a
transmembrane protein 39a
chr15_+_72913357 0.660 ENSMUST00000166418.2
Gm3150
predicted gene 3150
chrX_-_7319291 0.654 ENSMUST00000128319.1
Clcn5
chloride channel 5
chr8_-_112015036 0.647 ENSMUST00000071732.5
Gm6793
predicted gene 6793
chr10_+_93831555 0.637 ENSMUST00000095333.4
Usp44
ubiquitin specific peptidase 44
chr18_+_7869707 0.628 ENSMUST00000166062.1
ENSMUST00000169010.1
Wac

WW domain containing adaptor with coiled-coil

chr18_+_33464163 0.616 ENSMUST00000097634.3
Gm10549
predicted gene 10549
chr1_-_36273425 0.612 ENSMUST00000056946.6
Neurl3
neuralized homolog 3 homolog (Drosophila)
chr17_-_70998010 0.598 ENSMUST00000024846.6
Myl12a
myosin, light chain 12A, regulatory, non-sarcomeric

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
1.0 3.0 GO:0071918 urea transmembrane transport(GO:0071918)
0.9 2.7 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) DNA replication preinitiation complex assembly(GO:0071163) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.8 2.3 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.7 2.2 GO:0061349 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) hypophysis morphogenesis(GO:0048850) cervix development(GO:0060067) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354)
0.7 1.4 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.6 3.5 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.6 2.9 GO:0035063 nuclear speck organization(GO:0035063)
0.6 1.7 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.5 1.6 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.5 2.6 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.4 1.8 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.4 0.9 GO:1902956 regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902956)
0.4 3.3 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.4 1.6 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.4 1.5 GO:1903463 regulation of mitotic cell cycle DNA replication(GO:1903463)
0.4 1.1 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.4 1.5 GO:0070269 pyroptosis(GO:0070269)
0.4 2.2 GO:0046502 uroporphyrinogen III metabolic process(GO:0046502)
0.4 1.8 GO:0035262 gonad morphogenesis(GO:0035262)
0.4 0.4 GO:0003134 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134)
0.4 1.8 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.4 2.1 GO:0030913 paranodal junction assembly(GO:0030913)
0.4 1.1 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.3 2.4 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.3 5.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.3 2.4 GO:0035754 B cell chemotaxis(GO:0035754)
0.3 1.6 GO:0046864 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865) alveolar primary septum development(GO:0061143)
0.3 8.7 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.3 1.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.3 0.3 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.3 1.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.3 0.9 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.3 7.4 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.3 0.8 GO:0090327 negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.3 0.8 GO:0002430 complement receptor mediated signaling pathway(GO:0002430) GPI anchor release(GO:0006507)
0.3 3.5 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
0.2 2.2 GO:0042538 hyperosmotic salinity response(GO:0042538)
0.2 0.7 GO:2000314 negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.2 1.6 GO:0016584 nucleosome positioning(GO:0016584)
0.2 0.4 GO:0003347 epicardial cell to mesenchymal cell transition(GO:0003347)
0.2 3.6 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.2 0.8 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.2 0.8 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.2 1.8 GO:0001842 neural fold formation(GO:0001842)
0.2 1.5 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.2 10.2 GO:0070303 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.2 0.5 GO:0008594 photoreceptor cell morphogenesis(GO:0008594)
0.2 1.8 GO:0006228 UTP biosynthetic process(GO:0006228)
0.2 0.5 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.2 0.5 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.2 3.3 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.2 1.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.2 1.7 GO:0048733 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) sebaceous gland development(GO:0048733)
0.1 0.4 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 0.4 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.1 0.6 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.1 0.5 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.1 1.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 3.9 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 2.6 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.1 2.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.2 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.1 1.0 GO:0006013 mannose metabolic process(GO:0006013)
0.1 0.5 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.1 1.4 GO:0046697 decidualization(GO:0046697)
0.1 0.6 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 0.2 GO:1901355 response to rapamycin(GO:1901355)
0.1 0.3 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.1 8.2 GO:0046847 filopodium assembly(GO:0046847)
0.1 1.8 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 5.2 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 0.7 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 0.4 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 0.8 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.1 1.1 GO:0000729 DNA double-strand break processing(GO:0000729)
0.1 0.8 GO:0048102 autophagic cell death(GO:0048102)
0.1 1.8 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.1 0.7 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 0.3 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.1 0.2 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.1 0.5 GO:0061092 bile acid secretion(GO:0032782) regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.1 1.3 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.1 0.4 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.1 0.7 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 0.6 GO:0097475 motor neuron migration(GO:0097475)
0.1 1.0 GO:0051451 myoblast migration(GO:0051451)
0.1 0.5 GO:0050957 equilibrioception(GO:0050957)
0.1 0.3 GO:0002934 desmosome organization(GO:0002934)
0.1 1.8 GO:0007608 sensory perception of smell(GO:0007608)
0.1 0.6 GO:1904667 negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.1 0.2 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 2.2 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.1 1.0 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 0.2 GO:0045896 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.1 0.4 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 0.2 GO:0019441 tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) quinolinate biosynthetic process(GO:0019805) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218) kynurenine metabolic process(GO:0070189)
0.1 1.4 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 0.1 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.1 0.7 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 0.9 GO:1901629 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688) regulation of presynaptic membrane organization(GO:1901629)
0.1 2.0 GO:0072698 protein localization to microtubule cytoskeleton(GO:0072698)
0.0 0.2 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.6 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 3.0 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 5.7 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 1.5 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 1.1 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.2 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 0.9 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.4 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.0 1.3 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.3 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.2 GO:0009405 pathogenesis(GO:0009405)
0.0 2.5 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 2.0 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.3 GO:0042640 anagen(GO:0042640)
0.0 0.2 GO:0061743 motor learning(GO:0061743)
0.0 1.2 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 0.1 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.0 0.8 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.9 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 1.3 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.0 0.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.7 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.6 GO:0006825 copper ion transport(GO:0006825)
0.0 0.3 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.6 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 1.0 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.2 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.0 1.0 GO:0006505 GPI anchor metabolic process(GO:0006505) GPI anchor biosynthetic process(GO:0006506)
0.0 0.7 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.4 GO:0061157 mRNA destabilization(GO:0061157)
0.0 0.5 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.3 GO:0007602 phototransduction(GO:0007602)
0.0 0.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.5 GO:0010762 regulation of fibroblast migration(GO:0010762)
0.0 0.3 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.3 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 1.8 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.2 GO:0009404 toxin metabolic process(GO:0009404)
0.0 1.8 GO:1900006 positive regulation of dendrite development(GO:1900006)
0.0 1.0 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.3 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.3 GO:0031935 regulation of chromatin silencing(GO:0031935)
0.0 0.1 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.1 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.0 GO:0045006 DNA deamination(GO:0045006)
0.0 0.2 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.3 GO:0033120 positive regulation of RNA splicing(GO:0033120)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.7 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
1.6 4.8 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
1.4 4.1 GO:0005588 collagen type V trimer(GO:0005588)
1.3 5.0 GO:0008623 CHRAC(GO:0008623)
0.9 2.7 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.7 3.6 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.7 3.5 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.5 3.3 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.4 1.8 GO:0090537 CERF complex(GO:0090537)
0.4 1.8 GO:0070820 tertiary granule(GO:0070820)
0.4 1.5 GO:0061702 inflammasome complex(GO:0061702)
0.4 1.4 GO:0060187 cell pole(GO:0060187)
0.2 1.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.2 4.0 GO:0031616 spindle pole centrosome(GO:0031616)
0.2 1.4 GO:0097513 myosin II filament(GO:0097513)
0.2 4.3 GO:0097431 mitotic spindle pole(GO:0097431)
0.2 1.9 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 1.2 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.2 1.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 0.7 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.9 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.4 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.7 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.8 GO:0070531 BRCA1-A complex(GO:0070531)
0.1 0.6 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.5 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 0.3 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.1 0.6 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 0.6 GO:1990393 3M complex(GO:1990393)
0.1 1.5 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.4 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 1.2 GO:0031209 SCAR complex(GO:0031209)
0.1 1.1 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 2.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 1.0 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.1 1.6 GO:0031527 filopodium membrane(GO:0031527)
0.1 4.6 GO:0016459 myosin complex(GO:0016459)
0.1 0.9 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 0.5 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 0.5 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 3.5 GO:0000791 euchromatin(GO:0000791)
0.1 1.1 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.1 2.4 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.4 GO:0097452 GAIT complex(GO:0097452)
0.0 2.2 GO:0016235 aggresome(GO:0016235)
0.0 0.9 GO:0032279 asymmetric synapse(GO:0032279)
0.0 1.5 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.2 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.6 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 2.8 GO:0070469 respiratory chain(GO:0070469)
0.0 0.8 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.6 GO:0042555 MCM complex(GO:0042555)
0.0 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 3.2 GO:0005813 centrosome(GO:0005813)
0.0 0.4 GO:1990635 proximal dendrite(GO:1990635)
0.0 3.3 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.4 GO:0001741 XY body(GO:0001741)
0.0 3.3 GO:0043296 apical junction complex(GO:0043296)
0.0 0.8 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.7 GO:0000786 nucleosome(GO:0000786)
0.0 0.3 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 1.8 GO:0005604 basement membrane(GO:0005604)
0.0 1.5 GO:0016605 PML body(GO:0016605)
0.0 0.3 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.4 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.2 GO:0046930 pore complex(GO:0046930)
0.0 2.6 GO:0036464 cytoplasmic ribonucleoprotein granule(GO:0036464)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.2 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.9 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.6 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.7 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.2 GO:0045120 pronucleus(GO:0045120)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 8.7 GO:0050436 microfibril binding(GO:0050436)
1.2 4.8 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.9 3.5 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.7 2.2 GO:0005110 frizzled-2 binding(GO:0005110)
0.6 4.1 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.5 3.5 GO:0000150 recombinase activity(GO:0000150)
0.5 3.0 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.4 3.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.4 0.4 GO:0036361 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.4 2.4 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.4 2.6 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.4 2.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.3 1.4 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.3 1.2 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.3 1.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.3 1.1 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 2.8 GO:0043522 leucine zipper domain binding(GO:0043522)
0.2 3.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 1.9 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 2.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 1.2 GO:0070697 activin receptor binding(GO:0070697)
0.2 1.6 GO:0032564 dATP binding(GO:0032564)
0.2 0.7 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.2 1.0 GO:0004984 olfactory receptor activity(GO:0004984)
0.2 1.2 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 0.5 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.2 2.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 0.5 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.2 2.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 3.0 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 0.4 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.1 0.7 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.1 0.4 GO:0002134 UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.1 0.5 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 0.5 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 0.4 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.1 0.6 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.5 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.1 4.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.3 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 1.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.8 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.9 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 1.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 2.8 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.7 GO:1901612 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.1 1.6 GO:0017166 vinculin binding(GO:0017166)
0.1 1.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.6 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 1.1 GO:0070513 death domain binding(GO:0070513)
0.1 0.3 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.8 GO:0004630 phospholipase D activity(GO:0004630)
0.1 0.7 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 0.6 GO:0043237 laminin-1 binding(GO:0043237)
0.1 3.2 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.8 GO:0050733 RS domain binding(GO:0050733)
0.1 3.2 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 1.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 0.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.2 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.1 2.2 GO:0008198 ferrous iron binding(GO:0008198)
0.1 5.2 GO:0008186 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.1 1.0 GO:0016805 dipeptidase activity(GO:0016805)
0.1 1.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 3.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 0.3 GO:0038132 neuregulin binding(GO:0038132)
0.1 2.4 GO:0017091 AU-rich element binding(GO:0017091)
0.1 1.0 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.1 0.3 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 1.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.2 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.1 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 1.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.2 GO:0001083 transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083)
0.1 2.9 GO:0030507 spectrin binding(GO:0030507)
0.1 2.3 GO:0005507 copper ion binding(GO:0005507)
0.1 1.6 GO:0051183 vitamin transporter activity(GO:0051183)
0.1 0.4 GO:0019211 phosphatase activator activity(GO:0019211)
0.1 1.9 GO:0005109 frizzled binding(GO:0005109)
0.0 0.4 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.2 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.9 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 4.4 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 1.0 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.7 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 1.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 1.1 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.3 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.2 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 1.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.8 GO:0031690 adrenergic receptor binding(GO:0031690)
0.0 0.8 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.7 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.6 GO:0050811 GABA-A receptor activity(GO:0004890) GABA receptor binding(GO:0050811)
0.0 2.0 GO:0019894 kinesin binding(GO:0019894)
0.0 0.3 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 2.2 GO:0016209 antioxidant activity(GO:0016209)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 3.6 GO:0051015 actin filament binding(GO:0051015)
0.0 3.4 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.4 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.6 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.2 GO:0043422 protein kinase B binding(GO:0043422)
0.0 2.9 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.5 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.2 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.5 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 6.7 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.2 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.3 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.6 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.0 GO:0036468 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.3 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 4.1 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.2 7.7 NABA_COLLAGENS Genes encoding collagen proteins
0.1 3.8 PID_AURORA_A_PATHWAY Aurora A signaling
0.1 1.8 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.1 3.4 PID_ATM_PATHWAY ATM pathway
0.1 2.1 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.1 2.2 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.1 1.5 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.1 2.8 PID_ARF6_PATHWAY Arf6 signaling events
0.1 1.8 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.1 2.8 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 0.5 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 1.3 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 1.9 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.8 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.6 PID_BMP_PATHWAY BMP receptor signaling
0.0 1.2 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.9 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 0.3 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 1.1 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.5 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling
0.0 1.3 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 0.5 PID_CERAMIDE_PATHWAY Ceramide signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.7 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.3 2.4 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.2 2.7 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.2 7.6 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.2 1.5 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 3.0 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 1.5 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.5 REACTOME_INFLAMMASOMES Genes involved in Inflammasomes
0.1 2.2 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.6 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 1.4 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.1 2.4 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 3.0 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 1.2 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 2.6 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 1.8 REACTOME_ENOS_ACTIVATION_AND_REGULATION Genes involved in eNOS activation and regulation
0.1 0.5 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 1.6 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.1 0.3 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 1.4 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 1.6 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.1 0.7 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 2.3 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.4 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.8 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.9 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 1.3 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.3 REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.5 REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.3 REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.5 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 2.2 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.9 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.6 REACTOME_IRON_UPTAKE_AND_TRANSPORT Genes involved in Iron uptake and transport
0.0 1.0 REACTOME_CLEAVAGE_OF_GROWING_TRANSCRIPT_IN_THE_TERMINATION_REGION_ Genes involved in Cleavage of Growing Transcript in the Termination Region
0.0 0.2 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.7 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.1 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.2 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 1.4 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production