Motif ID: Hoxa6

Z-value: 0.980


Transcription factors associated with Hoxa6:

Gene SymbolEntrez IDGene Name
Hoxa6 ENSMUSG00000043219.8 Hoxa6



Activity profile for motif Hoxa6.

activity profile for motif Hoxa6


Sorted Z-values histogram for motif Hoxa6

Sorted Z-values for motif Hoxa6



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa6

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_71528657 28.389 ENSMUST00000126400.1
Dlx1
distal-less homeobox 1
chr14_-_118052235 17.030 ENSMUST00000022725.2
Dct
dopachrome tautomerase
chr19_-_59170978 16.897 ENSMUST00000172821.2
Vax1
ventral anterior homeobox containing gene 1
chr1_-_163313661 14.669 ENSMUST00000174397.1
ENSMUST00000075805.6
ENSMUST00000027878.7
Prrx1


paired related homeobox 1


chr7_-_37773555 13.752 ENSMUST00000176534.1
Zfp536
zinc finger protein 536
chr8_-_46294592 11.728 ENSMUST00000058636.7
Helt
helt bHLH transcription factor
chr7_-_116038734 10.821 ENSMUST00000166877.1
Sox6
SRY-box containing gene 6
chr14_-_48665098 9.940 ENSMUST00000118578.1
Otx2
orthodenticle homolog 2 (Drosophila)
chr13_-_103764502 9.618 ENSMUST00000074616.5
Srek1
splicing regulatory glutamine/lysine-rich protein 1
chr1_+_6730051 9.553 ENSMUST00000043578.6
ENSMUST00000131467.1
ENSMUST00000150761.1
ENSMUST00000151281.1
St18



suppression of tumorigenicity 18



chr16_+_42907563 9.252 ENSMUST00000151244.1
ENSMUST00000114694.2
Zbtb20

zinc finger and BTB domain containing 20

chr6_+_15185456 8.973 ENSMUST00000115472.1
ENSMUST00000115474.1
ENSMUST00000031545.7
ENSMUST00000137628.1
Foxp2



forkhead box P2



chr9_+_118478344 8.199 ENSMUST00000035020.8
Eomes
eomesodermin homolog (Xenopus laevis)
chr10_-_42583628 8.118 ENSMUST00000019938.4
Nr2e1
nuclear receptor subfamily 2, group E, member 1
chr2_+_38341068 7.827 ENSMUST00000133661.1
Lhx2
LIM homeobox protein 2
chr2_+_70474923 7.650 ENSMUST00000100043.2
Sp5
trans-acting transcription factor 5
chr4_+_11579647 7.303 ENSMUST00000180239.1
Fsbp
fibrinogen silencer binding protein
chr9_+_118478182 7.178 ENSMUST00000111763.1
Eomes
eomesodermin homolog (Xenopus laevis)
chr4_-_110292719 7.118 ENSMUST00000106601.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr18_-_84086379 7.090 ENSMUST00000060303.8
Tshz1
teashirt zinc finger family member 1
chr1_-_165934900 6.884 ENSMUST00000069609.5
ENSMUST00000111427.2
ENSMUST00000111426.4
Pou2f1


POU domain, class 2, transcription factor 1


chr2_+_20737306 6.683 ENSMUST00000114606.1
ENSMUST00000114608.1
Etl4

enhancer trap locus 4

chr19_+_55894508 6.396 ENSMUST00000142291.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr13_-_97747373 6.343 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr11_-_19018956 6.290 ENSMUST00000068264.7
ENSMUST00000144988.1
ENSMUST00000185131.1
Meis1


Meis homeobox 1


chr6_+_15196949 6.226 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
Foxp2



forkhead box P2



chr2_-_36104060 6.097 ENSMUST00000112961.3
ENSMUST00000112966.3
Lhx6

LIM homeobox protein 6

chr10_+_88091070 5.765 ENSMUST00000048621.7
Pmch
pro-melanin-concentrating hormone
chr6_+_15185203 5.655 ENSMUST00000154448.1
Foxp2
forkhead box P2
chr2_-_18048784 5.612 ENSMUST00000142856.1
Skida1
SKI/DACH domain containing 1
chr2_+_181767040 5.573 ENSMUST00000108756.1
Myt1
myelin transcription factor 1
chr11_+_102604370 5.459 ENSMUST00000057893.5
Fzd2
frizzled homolog 2 (Drosophila)
chr11_-_19018714 5.368 ENSMUST00000177417.1
Meis1
Meis homeobox 1
chr7_-_37772868 5.130 ENSMUST00000176205.1
Zfp536
zinc finger protein 536
chr9_+_120929216 5.038 ENSMUST00000130466.1
Ctnnb1
catenin (cadherin associated protein), beta 1
chr7_-_115824699 5.000 ENSMUST00000169129.1
Sox6
SRY-box containing gene 6
chr10_-_92164666 4.789 ENSMUST00000183123.1
ENSMUST00000182033.1
Rmst

rhabdomyosarcoma 2 associated transcript (non-coding RNA)

chr2_-_33942111 4.778 ENSMUST00000130988.1
ENSMUST00000127936.1
ENSMUST00000134271.1
Gm13403


predicted gene 13403


chr17_+_75178797 4.584 ENSMUST00000112516.1
ENSMUST00000135447.1
Ltbp1

latent transforming growth factor beta binding protein 1

chr12_-_34528844 4.529 ENSMUST00000110819.2
Hdac9
histone deacetylase 9
chr12_+_38783455 4.290 ENSMUST00000161980.1
ENSMUST00000160701.1
Etv1

ets variant gene 1

chr17_+_75178911 4.215 ENSMUST00000112514.1
Ltbp1
latent transforming growth factor beta binding protein 1
chr12_-_54986363 3.958 ENSMUST00000173433.1
ENSMUST00000173803.1
Baz1a
Gm20403
bromodomain adjacent to zinc finger domain 1A
predicted gene 20403
chr4_-_97584612 3.930 ENSMUST00000107068.2
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr4_-_97584605 3.928 ENSMUST00000107067.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr2_-_18048347 3.926 ENSMUST00000066885.5
Skida1
SKI/DACH domain containing 1
chr14_-_48662740 3.909 ENSMUST00000122009.1
Otx2
orthodenticle homolog 2 (Drosophila)
chr1_+_6734827 3.878 ENSMUST00000139838.1
St18
suppression of tumorigenicity 18
chr2_+_181767283 3.855 ENSMUST00000108757.2
Myt1
myelin transcription factor 1
chr5_+_149678224 3.809 ENSMUST00000100404.3
B3galtl
beta 1,3-galactosyltransferase-like
chr1_+_187997835 3.787 ENSMUST00000110938.1
Esrrg
estrogen-related receptor gamma
chr1_+_187997821 3.757 ENSMUST00000027906.6
Esrrg
estrogen-related receptor gamma
chr14_-_122451109 3.701 ENSMUST00000081580.2
Gm5089
predicted gene 5089
chr13_-_83729544 3.698 ENSMUST00000181705.1
Gm26803
predicted gene, 26803
chr5_-_106574706 3.656 ENSMUST00000131029.1
ENSMUST00000124394.2
RP24-421H18.1

RP24-421H18.1

chr1_-_166002613 3.635 ENSMUST00000177358.1
ENSMUST00000160908.1
ENSMUST00000027850.8
ENSMUST00000160260.2
Pou2f1



POU domain, class 2, transcription factor 1



chr12_-_54986328 3.579 ENSMUST00000038926.6
Baz1a
bromodomain adjacent to zinc finger domain 1A
chr12_+_38783503 3.562 ENSMUST00000159334.1
Etv1
ets variant gene 1
chr4_-_110287479 3.555 ENSMUST00000106598.1
ENSMUST00000102723.4
ENSMUST00000153906.1
Elavl4


ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)


chr1_-_166002591 3.549 ENSMUST00000111429.4
ENSMUST00000176800.1
Pou2f1

POU domain, class 2, transcription factor 1

chr2_-_116067391 3.510 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr14_+_28511344 3.469 ENSMUST00000112272.1
Wnt5a
wingless-related MMTV integration site 5A
chr15_-_8710734 3.324 ENSMUST00000005493.7
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr13_-_97747399 3.314 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr16_-_88056176 3.187 ENSMUST00000072256.5
ENSMUST00000023652.8
ENSMUST00000114137.1
Grik1


glutamate receptor, ionotropic, kainate 1


chr9_-_42399709 3.126 ENSMUST00000160940.1
Tecta
tectorin alpha
chr9_-_42399915 3.113 ENSMUST00000042190.7
Tecta
tectorin alpha
chr2_-_79456750 3.108 ENSMUST00000041099.4
Neurod1
neurogenic differentiation 1
chr9_-_60141220 3.065 ENSMUST00000034829.5
Thsd4
thrombospondin, type I, domain containing 4
chr1_+_104768510 3.060 ENSMUST00000062528.8
Cdh20
cadherin 20
chr17_-_58991343 2.900 ENSMUST00000025064.7
2610034M16Rik
RIKEN cDNA 2610034M16 gene
chr4_-_42168603 2.893 ENSMUST00000098121.3
Gm13305
predicted gene 13305
chr2_-_168767136 2.887 ENSMUST00000029061.5
ENSMUST00000103074.1
Sall4

sal-like 4 (Drosophila)

chr19_+_55895508 2.801 ENSMUST00000111646.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr6_+_34598530 2.794 ENSMUST00000115027.1
ENSMUST00000115026.1
Cald1

caldesmon 1

chr18_-_13972617 2.744 ENSMUST00000025288.7
Zfp521
zinc finger protein 521
chr2_+_79707780 2.733 ENSMUST00000090760.2
ENSMUST00000040863.4
ENSMUST00000111780.2
Ppp1r1c


protein phosphatase 1, regulatory (inhibitor) subunit 1C


chr17_-_51810866 2.695 ENSMUST00000176669.1
Satb1
special AT-rich sequence binding protein 1
chr16_+_43503607 2.662 ENSMUST00000126100.1
ENSMUST00000123047.1
ENSMUST00000156981.1
Zbtb20


zinc finger and BTB domain containing 20


chr3_-_52104891 2.660 ENSMUST00000121440.1
Maml3
mastermind like 3 (Drosophila)
chr14_+_75455957 2.586 ENSMUST00000164848.1
Siah3
seven in absentia homolog 3 (Drosophila)
chr10_-_13388753 2.582 ENSMUST00000105546.1
Phactr2
phosphatase and actin regulator 2
chr2_-_168767029 2.562 ENSMUST00000075044.3
Sall4
sal-like 4 (Drosophila)
chr2_+_116067933 2.558 ENSMUST00000156095.1
G630016G05Rik
RIKEN cDNA G630016G05 gene
chr6_+_34598500 2.449 ENSMUST00000079391.3
ENSMUST00000142512.1
Cald1

caldesmon 1

chr7_-_73541738 2.389 ENSMUST00000169922.2
Chd2
chromodomain helicase DNA binding protein 2
chr1_+_6730135 2.351 ENSMUST00000155921.1
St18
suppression of tumorigenicity 18
chr14_-_48667508 2.294 ENSMUST00000144465.1
ENSMUST00000133479.1
ENSMUST00000119070.1
ENSMUST00000152018.1
Otx2



orthodenticle homolog 2 (Drosophila)



chr6_+_34709442 2.288 ENSMUST00000115021.1
Cald1
caldesmon 1
chr2_-_28916412 2.285 ENSMUST00000050776.2
ENSMUST00000113849.1
Barhl1

BarH-like 1 (Drosophila)

chr3_+_102010138 2.196 ENSMUST00000066187.4
Nhlh2
nescient helix loop helix 2
chr16_+_43247278 2.148 ENSMUST00000114691.1
ENSMUST00000079441.6
Zbtb20

zinc finger and BTB domain containing 20

chrM_+_7005 2.132 ENSMUST00000082405.1
mt-Co2
mitochondrially encoded cytochrome c oxidase II
chr4_-_21685782 2.118 ENSMUST00000076206.4
Prdm13
PR domain containing 13
chr17_+_34592248 2.082 ENSMUST00000038149.6
Pbx2
pre B cell leukemia homeobox 2
chr7_-_49636847 2.038 ENSMUST00000032717.6
Dbx1
developing brain homeobox 1
chr15_-_8710409 2.024 ENSMUST00000157065.1
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr10_-_13388830 1.963 ENSMUST00000079698.5
Phactr2
phosphatase and actin regulator 2
chr3_+_41563356 1.962 ENSMUST00000163764.1
Phf17
PHD finger protein 17
chr4_-_82885148 1.902 ENSMUST00000048430.3
Cer1
cerberus 1 homolog (Xenopus laevis)
chr5_+_42067960 1.896 ENSMUST00000087332.4
Gm16223
predicted gene 16223
chr1_+_137928100 1.888 ENSMUST00000054333.2
A130050O07Rik
RIKEN cDNA A130050O07 gene
chr7_-_109170308 1.871 ENSMUST00000036992.7
Lmo1
LIM domain only 1
chr4_-_91399984 1.833 ENSMUST00000102799.3
Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr4_-_82850721 1.782 ENSMUST00000139401.1
Zdhhc21
zinc finger, DHHC domain containing 21
chr5_-_123141067 1.753 ENSMUST00000162697.1
ENSMUST00000160321.1
ENSMUST00000159637.1
AI480526


expressed sequence AI480526


chr1_-_87394721 1.747 ENSMUST00000113212.3
Kcnj13
potassium inwardly-rectifying channel, subfamily J, member 13
chr2_-_58052832 1.735 ENSMUST00000090940.5
Ermn
ermin, ERM-like protein
chr6_+_34709610 1.721 ENSMUST00000031775.6
Cald1
caldesmon 1
chr19_-_53371766 1.687 ENSMUST00000086887.1
Gm10197
predicted gene 10197
chr2_+_72297895 1.665 ENSMUST00000144111.1
Zak
sterile alpha motif and leucine zipper containing kinase AZK
chr16_+_43235856 1.605 ENSMUST00000146708.1
Zbtb20
zinc finger and BTB domain containing 20
chr2_-_64097994 1.534 ENSMUST00000131615.2
Fign
fidgetin
chr2_-_63184253 1.490 ENSMUST00000075052.3
ENSMUST00000112454.1
Kcnh7

potassium voltage-gated channel, subfamily H (eag-related), member 7

chr10_+_42860348 1.432 ENSMUST00000063063.7
Scml4
sex comb on midleg-like 4 (Drosophila)
chr2_-_170194033 1.378 ENSMUST00000180625.1
Gm17619
predicted gene, 17619
chr7_-_84679346 1.350 ENSMUST00000069537.2
ENSMUST00000178385.1
Zfand6

zinc finger, AN1-type domain 6

chr9_-_119825456 1.347 ENSMUST00000070617.7
Scn11a
sodium channel, voltage-gated, type XI, alpha
chr3_-_138131356 1.345 ENSMUST00000029805.8
Mttp
microsomal triglyceride transfer protein
chr4_-_92191749 1.321 ENSMUST00000123179.1
Gm12666
predicted gene 12666
chr14_-_46390501 1.318 ENSMUST00000100676.2
Bmp4
bone morphogenetic protein 4
chr8_-_67974567 1.312 ENSMUST00000098696.3
ENSMUST00000038959.9
ENSMUST00000093469.4
Psd3


pleckstrin and Sec7 domain containing 3


chr10_-_45470201 1.291 ENSMUST00000079390.6
Lin28b
lin-28 homolog B (C. elegans)
chr10_+_42860648 1.278 ENSMUST00000105495.1
Scml4
sex comb on midleg-like 4 (Drosophila)
chr13_-_78196373 1.273 ENSMUST00000125176.2
Nr2f1
nuclear receptor subfamily 2, group F, member 1
chr16_-_64786321 1.237 ENSMUST00000052588.4
Zfp654
zinc finger protein 654
chr4_+_128688726 1.233 ENSMUST00000106080.1
Phc2
polyhomeotic-like 2 (Drosophila)
chr13_+_44840686 1.226 ENSMUST00000173906.1
Jarid2
jumonji, AT rich interactive domain 2
chr10_+_42860776 1.219 ENSMUST00000105494.1
Scml4
sex comb on midleg-like 4 (Drosophila)
chr3_+_130180882 1.200 ENSMUST00000106353.1
ENSMUST00000080335.4
Col25a1

collagen, type XXV, alpha 1

chr2_-_72986716 1.158 ENSMUST00000112062.1
Gm11084
predicted gene 11084
chr18_+_42394539 1.146 ENSMUST00000025374.3
Pou4f3
POU domain, class 4, transcription factor 3
chr9_+_46998931 1.145 ENSMUST00000178065.1
Gm4791
predicted gene 4791
chr14_-_46390576 1.118 ENSMUST00000074077.5
Bmp4
bone morphogenetic protein 4
chr3_+_76075583 1.099 ENSMUST00000160261.1
Fstl5
follistatin-like 5
chr1_+_19103022 1.097 ENSMUST00000037294.7
Tfap2d
transcription factor AP-2, delta
chr5_+_115235836 1.075 ENSMUST00000081497.6
Pop5
processing of precursor 5, ribonuclease P/MRP family (S. cerevisiae)
chr5_+_34989473 1.000 ENSMUST00000114284.1
ENSMUST00000114285.1
Rgs12

regulator of G-protein signaling 12

chr2_+_132847719 1.000 ENSMUST00000124836.1
ENSMUST00000154160.1
Crls1

cardiolipin synthase 1

chr2_-_28916668 0.989 ENSMUST00000113847.1
Barhl1
BarH-like 1 (Drosophila)
chr5_+_13399309 0.955 ENSMUST00000030714.7
ENSMUST00000141968.1
Sema3a

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A

chr7_+_131542867 0.901 ENSMUST00000046093.5
Hmx3
H6 homeobox 3
chr8_-_67818284 0.900 ENSMUST00000120071.1
Psd3
pleckstrin and Sec7 domain containing 3
chr8_-_47352348 0.875 ENSMUST00000110367.2
Stox2
storkhead box 2
chr17_+_43952999 0.866 ENSMUST00000177857.1
Rcan2
regulator of calcineurin 2
chr12_-_73047179 0.829 ENSMUST00000050029.7
Six1
sine oculis-related homeobox 1
chr16_-_95459245 0.828 ENSMUST00000176345.1
ENSMUST00000121809.2
ENSMUST00000118113.1
ENSMUST00000122199.1
Erg



avian erythroblastosis virus E-26 (v-ets) oncogene related



chr13_+_80883403 0.817 ENSMUST00000099356.2
Arrdc3
arrestin domain containing 3
chr16_+_43364145 0.812 ENSMUST00000148775.1
Zbtb20
zinc finger and BTB domain containing 20
chr16_+_43363855 0.798 ENSMUST00000156367.1
Zbtb20
zinc finger and BTB domain containing 20
chr7_+_49910112 0.779 ENSMUST00000056442.5
Slc6a5
solute carrier family 6 (neurotransmitter transporter, glycine), member 5
chr4_+_107968332 0.774 ENSMUST00000106713.3
Slc1a7
solute carrier family 1 (glutamate transporter), member 7
chr1_+_19212054 0.741 ENSMUST00000064976.4
Tfap2b
transcription factor AP-2 beta
chr13_-_53473074 0.735 ENSMUST00000021922.8
Msx2
msh homeobox 2
chrM_+_2743 0.698 ENSMUST00000082392.1
mt-Nd1
mitochondrially encoded NADH dehydrogenase 1
chr2_-_63184170 0.647 ENSMUST00000112452.1
Kcnh7
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr11_-_33203588 0.629 ENSMUST00000037746.6
Tlx3
T cell leukemia, homeobox 3
chr16_-_56024628 0.619 ENSMUST00000119981.1
ENSMUST00000096021.3
Pcnp

PEST proteolytic signal containing nuclear protein

chr8_-_67818218 0.603 ENSMUST00000059374.4
Psd3
pleckstrin and Sec7 domain containing 3
chr13_-_18382041 0.603 ENSMUST00000139064.2
ENSMUST00000175703.2
Pou6f2

POU domain, class 6, transcription factor 2

chr2_-_168207063 0.559 ENSMUST00000088001.5
Adnp
activity-dependent neuroprotective protein
chr12_-_56613270 0.558 ENSMUST00000072631.5
Nkx2-9
NK2 homeobox 9
chr9_-_32541589 0.531 ENSMUST00000016231.7
Fli1
Friend leukemia integration 1
chr4_-_82705735 0.501 ENSMUST00000155821.1
Nfib
nuclear factor I/B
chr6_-_124840192 0.480 ENSMUST00000024206.5
Gnb3
guanine nucleotide binding protein (G protein), beta 3
chr18_-_47368446 0.470 ENSMUST00000076043.6
ENSMUST00000135790.1
Sema6a

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A

chr10_+_87859062 0.468 ENSMUST00000095360.4
Igf1
insulin-like growth factor 1
chr15_+_79690869 0.433 ENSMUST00000046463.8
Gtpbp1
GTP binding protein 1
chr2_+_26591423 0.428 ENSMUST00000152988.2
ENSMUST00000149789.1
Egfl7

EGF-like domain 7

chr11_+_100320596 0.418 ENSMUST00000152521.1
Eif1
eukaryotic translation initiation factor 1
chr11_+_77930800 0.413 ENSMUST00000093995.3
ENSMUST00000000646.7
Sez6

seizure related gene 6

chr2_+_120476911 0.393 ENSMUST00000110716.1
ENSMUST00000028748.6
ENSMUST00000090028.5
ENSMUST00000110719.2
Capn3



calpain 3



chr13_-_40730416 0.354 ENSMUST00000021787.5
Tfap2a
transcription factor AP-2, alpha
chr10_+_87859255 0.350 ENSMUST00000105300.2
Igf1
insulin-like growth factor 1
chr18_-_54990124 0.330 ENSMUST00000064763.5
Zfp608
zinc finger protein 608
chr5_+_13398688 0.321 ENSMUST00000125629.1
Sema3a
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr11_+_94044331 0.299 ENSMUST00000024979.8
Spag9
sperm associated antigen 9
chr9_-_105521147 0.270 ENSMUST00000176770.1
ENSMUST00000085133.6
Atp2c1

ATPase, Ca++-sequestering

chr1_-_30863256 0.258 ENSMUST00000088310.3
Phf3
PHD finger protein 3
chr8_-_105568298 0.240 ENSMUST00000005849.5
Agrp
agouti related protein
chr10_-_53638269 0.233 ENSMUST00000164393.1
Fam184a
family with sequence similarity 184, member A
chrM_+_10167 0.217 ENSMUST00000082414.1
mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chrM_+_8600 0.208 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chrM_+_7759 0.178 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr3_-_131344892 0.136 ENSMUST00000090246.4
ENSMUST00000126569.1
Sgms2

sphingomyelin synthase 2

chr2_-_168206875 0.118 ENSMUST00000057793.4
Adnp
activity-dependent neuroprotective protein
chr18_-_23041641 0.115 ENSMUST00000097651.3
Nol4
nucleolar protein 4
chr12_+_21417872 0.112 ENSMUST00000180671.1
Gm4419
predicted gene 4419
chr18_+_69593361 0.079 ENSMUST00000114978.2
ENSMUST00000114977.1
Tcf4

transcription factor 4

chr5_-_123140135 0.065 ENSMUST00000160099.1
AI480526
expressed sequence AI480526
chr18_+_54990280 0.064 ENSMUST00000181538.1
Gm4221
predicted gene 4221
chr11_+_94044241 0.044 ENSMUST00000103168.3
Spag9
sperm associated antigen 9
chr3_+_84952146 0.033 ENSMUST00000029727.7
Fbxw7
F-box and WD-40 domain protein 7
chr10_-_116549101 0.015 ENSMUST00000164088.1
Cnot2
CCR4-NOT transcription complex, subunit 2
chr11_+_116657106 0.007 ENSMUST00000116318.2
Gm11744
predicted gene 11744
chr7_-_70366735 0.007 ENSMUST00000089565.5
Nr2f2
nuclear receptor subfamily 2, group F, member 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
9.5 28.4 GO:0061075 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
5.1 15.4 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
4.0 16.1 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
2.8 17.0 GO:0006570 tyrosine metabolic process(GO:0006570)
2.4 7.1 GO:0060023 soft palate development(GO:0060023)
2.1 14.9 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
2.1 8.5 GO:0051884 regulation of anagen(GO:0051884)
2.1 16.9 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
1.9 5.8 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
1.8 5.5 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
1.7 14.0 GO:0048664 neuron fate determination(GO:0048664)
1.7 20.9 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
1.4 15.8 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
1.3 5.3 GO:0043490 malate-aspartate shuttle(GO:0043490)
1.3 15.8 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
1.3 9.2 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334)
1.2 6.1 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
1.2 2.4 GO:0072095 regulation of branch elongation involved in ureteric bud branching(GO:0072095)
1.2 18.9 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
1.0 3.1 GO:0003310 pancreatic A cell differentiation(GO:0003310) negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.9 9.4 GO:0060539 diaphragm development(GO:0060539)
0.8 5.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.8 7.6 GO:0097154 GABAergic neuron differentiation(GO:0097154)
0.7 7.9 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.6 1.9 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.6 7.8 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.6 12.9 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.6 1.7 GO:0046013 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.5 3.2 GO:0032229 positive regulation of gamma-aminobutyric acid secretion(GO:0014054) negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.5 2.6 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.5 4.5 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.4 3.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.4 17.3 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.4 2.5 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.4 8.8 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.3 7.6 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.3 0.7 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.3 5.4 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.3 1.1 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.3 0.8 GO:1900141 regulation of oligodendrocyte apoptotic process(GO:1900141) negative regulation of oligodendrocyte apoptotic process(GO:1900142)
0.3 0.8 GO:0090327 negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.3 1.3 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.3 0.8 GO:0036233 glycine import(GO:0036233)
0.2 0.7 GO:0097274 urea homeostasis(GO:0097274)
0.2 0.7 GO:0048818 positive regulation of hair follicle maturation(GO:0048818)
0.2 2.7 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.2 2.7 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.2 0.8 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.2 7.5 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.2 1.0 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.2 0.4 GO:0061303 oculomotor nerve development(GO:0021557) cornea development in camera-type eye(GO:0061303)
0.2 1.8 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.2 9.3 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.2 2.0 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 1.3 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 1.1 GO:0009249 protein lipoylation(GO:0009249)
0.1 0.4 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.1 0.6 GO:0044065 regulation of respiratory gaseous exchange by neurological system process(GO:0002087) regulation of respiratory system process(GO:0044065)
0.1 2.4 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.1 0.5 GO:0060486 Clara cell differentiation(GO:0060486) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 1.0 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.1 0.8 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 2.8 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 10.7 GO:0043488 regulation of mRNA stability(GO:0043488)
0.1 2.2 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.1 2.1 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 9.5 GO:0007605 sensory perception of sound(GO:0007605)
0.1 0.3 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.1 1.5 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.1 2.7 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1 1.7 GO:0010107 potassium ion import(GO:0010107)
0.1 7.6 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.1 1.3 GO:0006625 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 1.1 GO:0030901 midbrain development(GO:0030901)
0.0 2.2 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.2 GO:0008343 adult feeding behavior(GO:0008343) positive regulation of feeding behavior(GO:2000253)
0.0 0.7 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.5 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.4 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 2.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.3 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.9 GO:0060135 maternal process involved in female pregnancy(GO:0060135)
0.0 0.4 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.4 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.5 GO:0051642 centrosome localization(GO:0051642)
0.0 0.4 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.2 GO:0022904 respiratory electron transport chain(GO:0022904)
0.0 0.5 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.8 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
1.9 7.5 GO:0008623 CHRAC(GO:0008623)
1.6 14.2 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
1.0 9.3 GO:0030478 actin cap(GO:0030478)
0.7 10.7 GO:0042788 polysomal ribosome(GO:0042788)
0.6 17.0 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.5 3.2 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.4 1.3 GO:0044299 C-fiber(GO:0044299)
0.3 3.1 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.2 1.7 GO:0033269 internode region of axon(GO:0033269)
0.2 0.8 GO:0042567 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867) insulin-like growth factor ternary complex(GO:0042567)
0.2 1.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.2 68.3 GO:0005667 transcription factor complex(GO:0005667)
0.1 2.0 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 15.8 GO:0032993 protein-DNA complex(GO:0032993)
0.1 0.2 GO:0070469 respiratory chain(GO:0070469)
0.1 1.3 GO:0031528 microvillus membrane(GO:0031528)
0.1 1.2 GO:0035102 PRC1 complex(GO:0035102)
0.1 1.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 2.8 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 2.7 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 9.6 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.9 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.4 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 1.4 GO:0097440 apical dendrite(GO:0097440)
0.0 0.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 7.4 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 4.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 8.8 GO:0050436 microfibril binding(GO:0050436)
2.1 16.9 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
1.3 17.0 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
1.2 3.5 GO:0005110 frizzled-2 binding(GO:0005110)
1.1 15.9 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.9 5.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.6 1.9 GO:0016015 morphogen activity(GO:0016015)
0.6 7.5 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.5 3.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.5 95.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.5 5.0 GO:0045294 alpha-catenin binding(GO:0045294)
0.4 9.2 GO:0070016 gamma-catenin binding(GO:0045295) armadillo repeat domain binding(GO:0070016)
0.4 20.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.4 1.1 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.3 2.7 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.3 2.4 GO:0039706 co-receptor binding(GO:0039706)
0.3 10.7 GO:0017091 AU-rich element binding(GO:0017091)
0.3 5.8 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.2 5.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 4.5 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2 3.9 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.2 6.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 96.4 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.1 2.2 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 1.3 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.8 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.1 2.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.8 GO:0031690 adrenergic receptor binding(GO:0031690)
0.1 0.3 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.1 1.8 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 1.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 0.8 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.1 1.3 GO:0005248 voltage-gated sodium channel activity(GO:0005248)
0.0 0.4 GO:0031432 titin binding(GO:0031432)
0.0 2.1 GO:0042054 histone methyltransferase activity(GO:0042054)
0.0 1.1 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 1.6 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 0.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.8 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.9 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 1.3 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 1.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.7 GO:0005507 copper ion binding(GO:0005507)
0.0 0.5 GO:0030507 spectrin binding(GO:0030507)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 15.4 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.3 12.2 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.3 8.9 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.2 7.9 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.2 22.7 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 18.1 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.7 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 4.3 PID_BMP_PATHWAY BMP receptor signaling
0.1 4.6 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 4.5 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 3.0 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 0.5 PID_CONE_PATHWAY Visual signal transduction: Cones
0.0 1.2 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.8 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.0 0.5 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 1.3 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.2 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 5.0 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.5 14.1 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.2 9.3 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 3.2 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 15.5 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.2 2.7 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 3.1 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.1 9.4 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 0.8 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 6.1 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 1.0 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.1 1.3 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.3 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.9 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.1 0.5 REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 1.8 REACTOME_ENOS_ACTIVATION_AND_REGULATION Genes involved in eNOS activation and regulation
0.1 5.8 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 2.7 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 2.1 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.5 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.2 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation