Motif ID: Hoxa9_Hoxb9

Z-value: 0.515

Transcription factors associated with Hoxa9_Hoxb9:

Gene SymbolEntrez IDGene Name
Hoxa9 ENSMUSG00000038227.9 Hoxa9
Hoxb9 ENSMUSG00000020875.8 Hoxb9






Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa9_Hoxb9

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_57197435 6.082 ENSMUST00000111550.1
Ablim1
actin-binding LIM protein 1
chr19_-_57197377 5.975 ENSMUST00000111546.1
Ablim1
actin-binding LIM protein 1
chr6_+_49822710 4.524 ENSMUST00000031843.6
Npy
neuropeptide Y
chr13_+_16014457 2.760 ENSMUST00000164993.1
Inhba
inhibin beta-A
chr19_-_57197496 2.715 ENSMUST00000111544.1
Ablim1
actin-binding LIM protein 1
chr7_-_142661858 2.604 ENSMUST00000145896.2
Igf2
insulin-like growth factor 2
chr19_-_57197556 2.439 ENSMUST00000099294.2
Ablim1
actin-binding LIM protein 1
chr2_-_33087169 1.719 ENSMUST00000102810.3
Garnl3
GTPase activating RANGAP domain-like 3
chr11_-_109298066 1.657 ENSMUST00000106706.1
Rgs9
regulator of G-protein signaling 9
chr8_+_93810832 1.612 ENSMUST00000034198.8
ENSMUST00000125716.1
Gnao1

guanine nucleotide binding protein, alpha O

chr2_-_33086366 1.585 ENSMUST00000049618.2
Garnl3
GTPase activating RANGAP domain-like 3
chr19_-_45812291 1.442 ENSMUST00000086993.4
Kcnip2
Kv channel-interacting protein 2
chr18_+_37400845 1.435 ENSMUST00000057228.1
Pcdhb9
protocadherin beta 9
chr3_+_108591279 1.415 ENSMUST00000051145.8
ENSMUST00000139626.1
Wdr47

WD repeat domain 47

chr2_+_125136692 1.404 ENSMUST00000099452.2
Ctxn2
cortexin 2
chr18_-_31447383 1.401 ENSMUST00000025110.3
Syt4
synaptotagmin IV
chr11_-_79504078 1.398 ENSMUST00000164465.2
Omg
oligodendrocyte myelin glycoprotein
chr16_+_91225550 1.374 ENSMUST00000035608.8
Olig2
oligodendrocyte transcription factor 2
chrX_+_159840463 1.246 ENSMUST00000112451.1
ENSMUST00000112453.2
Sh3kbp1

SH3-domain kinase binding protein 1

chr3_+_138065052 1.227 ENSMUST00000163080.2
1110002E22Rik
RIKEN cDNA 1110002E22 gene
chr19_-_7341848 1.194 ENSMUST00000171393.1
Mark2
MAP/microtubule affinity-regulating kinase 2
chr4_-_49597860 1.189 ENSMUST00000042750.2
Tmem246
transmembrane protein 246
chr3_+_98280427 1.114 ENSMUST00000090746.2
ENSMUST00000120541.1
Hmgcs2

3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2

chr4_+_74013442 1.082 ENSMUST00000098006.2
ENSMUST00000084474.5
Frmd3

FERM domain containing 3

chr18_-_31317043 1.070 ENSMUST00000139924.1
ENSMUST00000153060.1
Rit2

Ras-like without CAAX 2

chr7_+_28277706 0.953 ENSMUST00000094651.2
Eid2b
EP300 interacting inhibitor of differentiation 2B
chr16_-_52454074 0.949 ENSMUST00000023312.7
Alcam
activated leukocyte cell adhesion molecule
chr13_-_91388079 0.924 ENSMUST00000181054.1
A830009L08Rik
RIKEN cDNA A830009L08 gene
chr1_+_66386968 0.899 ENSMUST00000145419.1
Map2
microtubule-associated protein 2
chr2_-_45112890 0.890 ENSMUST00000076836.6
Zeb2
zinc finger E-box binding homeobox 2
chr5_-_73191848 0.878 ENSMUST00000176910.1
Fryl
furry homolog-like (Drosophila)
chr7_+_56050135 0.866 ENSMUST00000076226.6
Herc2
hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 2
chr5_-_66514815 0.840 ENSMUST00000161879.1
ENSMUST00000159357.1
Apbb2

amyloid beta (A4) precursor protein-binding, family B, member 2

chr7_+_28693997 0.835 ENSMUST00000108280.1
Fbxo27
F-box protein 27
chr2_+_32395896 0.773 ENSMUST00000028162.3
Ptges2
prostaglandin E synthase 2
chr17_-_91092715 0.746 ENSMUST00000160800.2
ENSMUST00000159778.1
ENSMUST00000160844.3
Nrxn1


neurexin I


chr3_-_113574242 0.743 ENSMUST00000142505.2
Amy1
amylase 1, salivary
chr7_-_127449109 0.732 ENSMUST00000053392.4
Zfp689
zinc finger protein 689
chr8_+_112570043 0.721 ENSMUST00000034225.6
ENSMUST00000118171.1
Cntnap4

contactin associated protein-like 4

chr15_-_79062866 0.703 ENSMUST00000151889.1
ENSMUST00000040676.4
Ankrd54

ankyrin repeat domain 54

chr7_-_127448993 0.688 ENSMUST00000106299.1
Zfp689
zinc finger protein 689
chr1_+_89454769 0.667 ENSMUST00000027521.8
ENSMUST00000074945.5
Agap1

ArfGAP with GTPase domain, ankyrin repeat and PH domain 1

chr14_+_20674311 0.649 ENSMUST00000048657.8
Sec24c
Sec24 related gene family, member C (S. cerevisiae)
chr17_-_6621267 0.647 ENSMUST00000115772.3
Tmem181c-ps
transmembrane protein 181C, pseudogene
chr15_+_81936753 0.640 ENSMUST00000038757.7
Csdc2
cold shock domain containing C2, RNA binding
chr6_+_51523901 0.633 ENSMUST00000049152.8
Snx10
sorting nexin 10
chr6_-_143947061 0.631 ENSMUST00000124233.1
Sox5
SRY-box containing gene 5
chr9_+_121366958 0.602 ENSMUST00000045903.6
Trak1
trafficking protein, kinesin binding 1
chr14_-_70323783 0.564 ENSMUST00000151011.1
Slc39a14
solute carrier family 39 (zinc transporter), member 14
chr9_+_75311395 0.563 ENSMUST00000076889.6
Gnb5
guanine nucleotide binding protein (G protein), beta 5
chr15_+_85510812 0.561 ENSMUST00000079690.2
Gm4825
predicted pseudogene 4825
chr5_-_32746317 0.542 ENSMUST00000135248.1
Pisd
phosphatidylserine decarboxylase
chr3_+_84952146 0.540 ENSMUST00000029727.7
Fbxw7
F-box and WD-40 domain protein 7
chr15_+_81936911 0.538 ENSMUST00000135663.1
Csdc2
cold shock domain containing C2, RNA binding
chr6_-_97148908 0.529 ENSMUST00000142116.1
ENSMUST00000113387.1
Eogt

EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase

chr19_+_44203265 0.520 ENSMUST00000026220.5
Scd3
stearoyl-coenzyme A desaturase 3
chr11_-_109298090 0.509 ENSMUST00000106704.2
Rgs9
regulator of G-protein signaling 9
chr6_-_143947092 0.508 ENSMUST00000144289.1
ENSMUST00000111748.1
Sox5

SRY-box containing gene 5

chr10_-_63927434 0.507 ENSMUST00000079279.3
Gm10118
predicted gene 10118
chr2_+_180967291 0.481 ENSMUST00000108859.1
Arfgap1
ADP-ribosylation factor GTPase activating protein 1
chr7_+_110768169 0.466 ENSMUST00000170374.1
Ampd3
adenosine monophosphate deaminase 3
chr7_+_142533012 0.457 ENSMUST00000038675.6
Mrpl23
mitochondrial ribosomal protein L23
chr5_+_145204523 0.400 ENSMUST00000085671.3
ENSMUST00000031601.7
Zkscan5

zinc finger with KRAB and SCAN domains 5

chr5_-_145201829 0.397 ENSMUST00000162220.1
ENSMUST00000031632.8
Zkscan14

zinc finger with KRAB and SCAN domains 14

chr9_+_64235201 0.395 ENSMUST00000039011.3
Uchl4
ubiquitin carboxyl-terminal esterase L4
chr3_-_96905294 0.387 ENSMUST00000029738.7
Gpr89
G protein-coupled receptor 89
chr9_+_92309362 0.382 ENSMUST00000098477.1
ENSMUST00000150594.1
1700057G04Rik

RIKEN cDNA 1700057G04 gene

chr4_+_44012661 0.374 ENSMUST00000107849.3
ENSMUST00000107851.3
ENSMUST00000107845.3
Clta


clathrin, light polypeptide (Lca)


chr9_+_122351555 0.369 ENSMUST00000156520.1
Abhd5
abhydrolase domain containing 5
chr7_-_30232186 0.362 ENSMUST00000006254.5
Tbcb
tubulin folding cofactor B
chr2_-_31845925 0.343 ENSMUST00000028188.7
Fibcd1
fibrinogen C domain containing 1
chr19_-_7341792 0.333 ENSMUST00000164205.1
ENSMUST00000165286.1
ENSMUST00000168324.1
ENSMUST00000032557.8
Mark2



MAP/microtubule affinity-regulating kinase 2



chr19_-_56548122 0.327 ENSMUST00000026063.5
ENSMUST00000182276.1
Dclre1a

DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae)

chr19_-_56548013 0.323 ENSMUST00000182059.1
Dclre1a
DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae)
chr4_+_44012638 0.306 ENSMUST00000107847.3
ENSMUST00000170241.1
Clta

clathrin, light polypeptide (Lca)

chr17_-_45572495 0.302 ENSMUST00000130406.1
Hsp90ab1
heat shock protein 90 alpha (cytosolic), class B member 1
chr2_-_27463994 0.296 ENSMUST00000164296.1
Brd3
bromodomain containing 3
chr1_+_194619815 0.265 ENSMUST00000027952.5
Plxna2
plexin A2
chr11_-_115933464 0.240 ENSMUST00000021097.3
Recql5
RecQ protein-like 5
chr3_+_66985680 0.236 ENSMUST00000065047.6
Rsrc1
arginine/serine-rich coiled-coil 1
chr5_+_31452427 0.235 ENSMUST00000076264.4
Zfp512
zinc finger protein 512
chr3_-_95106907 0.214 ENSMUST00000107233.2
Pip5k1a
phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha
chr2_-_58052832 0.209 ENSMUST00000090940.5
Ermn
ermin, ERM-like protein
chr7_+_30231884 0.207 ENSMUST00000019882.9
Polr2i
polymerase (RNA) II (DNA directed) polypeptide I
chr11_-_109472611 0.198 ENSMUST00000168740.1
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr7_+_45062429 0.185 ENSMUST00000107830.1
ENSMUST00000003513.3
ENSMUST00000107829.1
ENSMUST00000150609.1
Nosip



nitric oxide synthase interacting protein



chr17_+_33638056 0.157 ENSMUST00000052079.7
Pram1
PML-RAR alpha-regulated adaptor molecule 1
chr5_-_107869153 0.150 ENSMUST00000128723.1
ENSMUST00000124034.1
Evi5

ecotropic viral integration site 5

chr3_+_66985947 0.148 ENSMUST00000161726.1
ENSMUST00000160504.1
Rsrc1

arginine/serine-rich coiled-coil 1

chr9_-_101198999 0.141 ENSMUST00000066773.7
Ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr10_-_80590292 0.139 ENSMUST00000003436.5
Abhd17a
abhydrolase domain containing 17A
chr6_+_104492790 0.133 ENSMUST00000161446.1
ENSMUST00000161070.1
ENSMUST00000089215.5
Cntn6


contactin 6


chr8_+_27042555 0.115 ENSMUST00000033875.8
ENSMUST00000098851.4
Prosc

proline synthetase co-transcribed

chr8_-_111992258 0.113 ENSMUST00000034427.5
ENSMUST00000139820.1
Adat1

adenosine deaminase, tRNA-specific 1

chr3_+_66985647 0.102 ENSMUST00000162362.1
ENSMUST00000065074.7
Rsrc1

arginine/serine-rich coiled-coil 1

chr17_-_34862473 0.088 ENSMUST00000025229.4
ENSMUST00000176203.2
ENSMUST00000128767.1
Cfb


complement factor B


chr8_+_9977707 0.080 ENSMUST00000139793.1
ENSMUST00000048216.5
Abhd13

abhydrolase domain containing 13

chr5_+_137787769 0.079 ENSMUST00000035852.7
Zcwpw1
zinc finger, CW type with PWWP domain 1
chr2_-_67433181 0.079 ENSMUST00000180773.1
Gm26727
predicted gene, 26727
chr5_+_34999111 0.074 ENSMUST00000114283.1
Rgs12
regulator of G-protein signaling 12
chr2_-_165287755 0.063 ENSMUST00000109298.1
ENSMUST00000109299.1
ENSMUST00000130393.1
ENSMUST00000017808.7
ENSMUST00000131409.1
ENSMUST00000156134.1
ENSMUST00000133961.1
Slc35c2






solute carrier family 35, member C2






chr6_-_124965207 0.059 ENSMUST00000148485.1
Cops7a
COP9 (constitutive photomorphogenic) homolog, subunit 7a (Arabidopsis thaliana)
chr7_+_43690418 0.054 ENSMUST00000056329.6
Klk14
kallikrein related-peptidase 14
chr12_-_100159601 0.033 ENSMUST00000021596.7
Nrde2
nrde-2 necessary for RNA interference, domain containing
chr18_+_37655891 0.031 ENSMUST00000097608.2
3222401L13Rik
RIKEN cDNA 3222401L13 gene
chr3_+_66985700 0.028 ENSMUST00000046542.6
ENSMUST00000162693.1
Rsrc1

arginine/serine-rich coiled-coil 1

chr7_-_141434532 0.024 ENSMUST00000133021.1
ENSMUST00000106007.3
ENSMUST00000150026.1
ENSMUST00000133206.2
Slc25a22



solute carrier family 25 (mitochondrial carrier, glutamate), member 22



chr5_+_34999070 0.003 ENSMUST00000114280.1
Rgs12
regulator of G-protein signaling 12

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.8 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.5 1.4 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.3 2.6 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.3 4.5 GO:0032098 regulation of appetite(GO:0032098)
0.3 1.4 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.2 1.1 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.2 0.7 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
0.2 16.9 GO:0030032 lamellipodium assembly(GO:0030032)
0.2 1.4 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.2 1.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 0.9 GO:1903056 melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.1 0.9 GO:0090527 actin filament reorganization(GO:0090527)
0.1 0.5 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 0.5 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 0.3 GO:0097278 transforming growth factor beta activation(GO:0036363) complement-dependent cytotoxicity(GO:0097278)
0.1 4.3 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.1 0.4 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891) positive regulation of triglyceride catabolic process(GO:0010898)
0.1 0.7 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 0.2 GO:0001193 maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193)
0.1 0.6 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.1 0.5 GO:0032264 IMP salvage(GO:0032264)
0.1 0.7 GO:2000821 regulation of grooming behavior(GO:2000821)
0.1 0.2 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 1.4 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.1 0.4 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 0.6 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.8 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 1.1 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 1.2 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.7 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.6 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.9 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.2 GO:0043313 regulation of neutrophil degranulation(GO:0043313)
0.0 1.4 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.1 GO:0015786 UDP-glucose transport(GO:0015786)
0.0 0.1 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.0 0.2 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.5 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.5 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 1.2 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 3.3 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 2.2 GO:0001764 neuron migration(GO:0001764)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0043512 inhibin A complex(GO:0043512)
0.3 1.1 GO:0097447 dendritic tree(GO:0097447)
0.2 0.7 GO:0099631 postsynaptic endocytic zone cytoplasmic component(GO:0099631)
0.2 1.5 GO:0097427 microtubule bundle(GO:0097427)
0.1 15.1 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 0.5 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.9 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 1.4 GO:0097449 dense core granule(GO:0031045) astrocyte projection(GO:0097449)
0.1 0.7 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.6 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 3.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.9 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.6 GO:1904115 axon cytoplasm(GO:1904115)
0.0 4.5 GO:0043195 terminal bouton(GO:0043195)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.6 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 1.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.7 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.8 GO:0070699 type II activin receptor binding(GO:0070699)
0.4 1.4 GO:0030348 syntaxin-3 binding(GO:0030348)
0.3 6.1 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.3 1.4 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.2 0.7 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.2 0.8 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.2 1.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.2 0.5 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 0.5 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.1 0.5 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1 0.9 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 0.5 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 2.6 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 0.3 GO:0008061 chitin binding(GO:0008061)
0.1 1.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.7 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 0.5 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.7 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 0.7 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 1.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.6 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.1 0.3 GO:0002135 CTP binding(GO:0002135)
0.0 0.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.6 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.9 GO:0032183 SUMO binding(GO:0032183)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.4 GO:0008308 voltage-gated anion channel activity(GO:0008308)
0.0 0.6 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 11.8 GO:0003779 actin binding(GO:0003779)
0.0 0.9 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.8 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 1.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 5.9 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.2 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 1.4 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.7 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.1 1.6 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.1 2.8 PID_ALK1_PATHWAY ALK1 signaling events
0.0 1.4 PID_ARF_3PATHWAY Arf1 pathway
0.0 2.6 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 2.4 PID_LKB1_PATHWAY LKB1 signaling events
0.0 1.1 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.8 PID_IFNG_PATHWAY IFN-gamma pathway
0.0 0.5 PID_MYC_PATHWAY C-MYC pathway
0.0 1.4 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 1.1 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.9 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 0.5 PID_HNF3A_PATHWAY FOXA1 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.8 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.6 17.2 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.2 2.6 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 6.8 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.1 2.2 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.1 1.1 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.1 0.3 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.9 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.5 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.6 REACTOME_ANTIGEN_PRESENTATION_FOLDING_ASSEMBLY_AND_PEPTIDE_LOADING_OF_CLASS_I_MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.5 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.4 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.3 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.1 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.0 0.4 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.5 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.2 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 1.4 REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING Genes involved in p75 NTR receptor-mediated signalling