Motif ID: Hoxb13
Z-value: 0.722
Transcription factors associated with Hoxb13:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Hoxb13 | ENSMUSG00000049604.3 | Hoxb13 |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 318 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 7.0 | GO:0046847 | filopodium assembly(GO:0046847) |
| 0.1 | 5.1 | GO:0006284 | base-excision repair(GO:0006284) |
| 0.1 | 4.1 | GO:0070303 | negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303) |
| 0.2 | 3.8 | GO:0021521 | ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573) |
| 0.0 | 3.8 | GO:0006261 | DNA-dependent DNA replication(GO:0006261) |
| 0.4 | 3.0 | GO:0042148 | strand invasion(GO:0042148) |
| 0.1 | 2.9 | GO:0008631 | intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631) |
| 0.7 | 2.8 | GO:1904565 | response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566) |
| 0.1 | 2.7 | GO:0051310 | metaphase plate congression(GO:0051310) |
| 0.8 | 2.4 | GO:0021557 | oculomotor nerve development(GO:0021557) |
| 0.2 | 2.4 | GO:0034219 | carbohydrate transmembrane transport(GO:0034219) |
| 0.1 | 2.4 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) |
| 0.7 | 2.2 | GO:0071918 | urea transmembrane transport(GO:0071918) |
| 0.4 | 2.2 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
| 0.4 | 2.1 | GO:0007386 | compartment pattern specification(GO:0007386) |
| 0.3 | 2.1 | GO:0034720 | histone H3-K4 demethylation(GO:0034720) |
| 0.2 | 2.1 | GO:0090308 | regulation of methylation-dependent chromatin silencing(GO:0090308) |
| 0.1 | 2.1 | GO:0040034 | regulation of development, heterochronic(GO:0040034) |
| 0.0 | 2.1 | GO:0006749 | glutathione metabolic process(GO:0006749) |
| 0.3 | 2.0 | GO:0021798 | forebrain dorsal/ventral pattern formation(GO:0021798) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 156 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.7 | GO:0016459 | myosin complex(GO:0016459) |
| 0.0 | 4.9 | GO:0005925 | focal adhesion(GO:0005925) |
| 1.4 | 4.1 | GO:0030868 | smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425) |
| 0.0 | 3.8 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.0 | 3.4 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.2 | 3.2 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.8 | 3.1 | GO:0008623 | CHRAC(GO:0008623) |
| 0.2 | 3.0 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.0 | 3.0 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.1 | 2.9 | GO:0005657 | replication fork(GO:0005657) |
| 0.0 | 2.9 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 2.9 | GO:0036464 | cytoplasmic ribonucleoprotein granule(GO:0036464) |
| 0.5 | 2.4 | GO:0005587 | collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651) |
| 0.0 | 2.4 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.0 | 2.3 | GO:0015934 | large ribosomal subunit(GO:0015934) |
| 0.7 | 2.2 | GO:0038045 | large latent transforming growth factor-beta complex(GO:0038045) |
| 0.3 | 2.2 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 0.0 | 2.2 | GO:0000776 | kinetochore(GO:0000776) |
| 0.0 | 2.1 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.0 | 2.1 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 216 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 7.4 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.0 | 4.9 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.6 | 4.5 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915) |
| 1.0 | 4.2 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
| 0.4 | 3.4 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
| 0.4 | 3.0 | GO:0000150 | recombinase activity(GO:0000150) |
| 1.0 | 2.9 | GO:0004731 | purine-nucleoside phosphorylase activity(GO:0004731) |
| 1.0 | 2.9 | GO:0033829 | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829) |
| 0.1 | 2.9 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.1 | 2.9 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.1 | 2.8 | GO:0071837 | HMG box domain binding(GO:0071837) |
| 0.6 | 2.2 | GO:0050436 | microfibril binding(GO:0050436) |
| 0.6 | 2.2 | GO:0044729 | hemi-methylated DNA-binding(GO:0044729) |
| 0.4 | 2.2 | GO:0015204 | urea transmembrane transporter activity(GO:0015204) |
| 0.2 | 2.2 | GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity(GO:0051575) |
| 0.1 | 2.2 | GO:0015144 | carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476) |
| 0.0 | 2.2 | GO:0001046 | core promoter sequence-specific DNA binding(GO:0001046) |
| 0.3 | 2.1 | GO:0032453 | histone demethylase activity (H3-K4 specific)(GO:0032453) |
| 0.2 | 2.1 | GO:0043237 | laminin-1 binding(GO:0043237) |
| 0.1 | 2.1 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
Gene overrepresentation in C2:CP category:
Showing 1 to 20 of 45 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 5.0 | PID_MYC_ACTIV_PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.1 | 4.9 | PID_NETRIN_PATHWAY | Netrin-mediated signaling events |
| 0.1 | 4.3 | PID_FANCONI_PATHWAY | Fanconi anemia pathway |
| 0.1 | 4.1 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
| 0.1 | 3.7 | PID_FGF_PATHWAY | FGF signaling pathway |
| 0.1 | 3.2 | PID_AURORA_A_PATHWAY | Aurora A signaling |
| 0.1 | 2.9 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
| 0.1 | 2.9 | PID_AURORA_B_PATHWAY | Aurora B signaling |
| 0.1 | 2.6 | PID_SMAD2_3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.1 | 2.6 | PID_LYSOPHOSPHOLIPID_PATHWAY | LPA receptor mediated events |
| 0.0 | 2.5 | PID_E2F_PATHWAY | E2F transcription factor network |
| 0.1 | 2.1 | PID_BARD1_PATHWAY | BARD1 signaling events |
| 0.0 | 1.9 | ST_WNT_BETA_CATENIN_PATHWAY | Wnt/beta-catenin Pathway |
| 0.1 | 1.7 | PID_LPA4_PATHWAY | LPA4-mediated signaling events |
| 0.0 | 1.5 | PID_P38_MK2_PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.0 | 1.5 | PID_FCER1_PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 0.1 | 1.4 | SA_G1_AND_S_PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 0.1 | 1.4 | PID_HEDGEHOG_2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.1 | 1.3 | PID_ERBB_NETWORK_PATHWAY | ErbB receptor signaling network |
| 0.1 | 1.2 | PID_ER_NONGENOMIC_PATHWAY | Plasma membrane estrogen receptor signaling |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 94 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.3 | REACTOME_NETRIN1_SIGNALING | Genes involved in Netrin-1 signaling |
| 0.0 | 4.6 | REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION | Genes involved in Influenza Viral RNA Transcription and Replication |
| 0.2 | 3.6 | REACTOME_PROCESSIVE_SYNTHESIS_ON_THE_LAGGING_STRAND | Genes involved in Processive synthesis on the lagging strand |
| 0.0 | 3.5 | REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.2 | 3.4 | REACTOME_FGFR_LIGAND_BINDING_AND_ACTIVATION | Genes involved in FGFR ligand binding and activation |
| 0.0 | 3.2 | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT | Genes involved in Respiratory electron transport |
| 0.1 | 2.9 | REACTOME_PACKAGING_OF_TELOMERE_ENDS | Genes involved in Packaging Of Telomere Ends |
| 0.2 | 2.7 | REACTOME_G1_S_SPECIFIC_TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 0.1 | 2.6 | REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT | Genes involved in Regulation of beta-cell development |
| 0.1 | 2.4 | REACTOME_METABOLISM_OF_POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.1 | 2.4 | REACTOME_G0_AND_EARLY_G1 | Genes involved in G0 and Early G1 |
| 0.0 | 2.4 | REACTOME_COLLAGEN_FORMATION | Genes involved in Collagen formation |
| 0.3 | 2.3 | REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 0.0 | 2.3 | REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.1 | 2.2 | REACTOME_KINESINS | Genes involved in Kinesins |
| 0.2 | 2.1 | REACTOME_PURINE_CATABOLISM | Genes involved in Purine catabolism |
| 0.1 | 2.1 | REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.1 | 1.9 | REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS | Genes involved in Amine compound SLC transporters |
| 0.2 | 1.8 | REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.1 | 1.8 | REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
