Motif ID: Hoxb4
Z-value: 0.439
Transcription factors associated with Hoxb4:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Hoxb4 | ENSMUSG00000038692.7 | Hoxb4 |
Top targets:
Showing 1 to 20 of 43 entries
Gene overrepresentation in biological_process category:
Showing 1 to 16 of 16 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 4.9 | GO:0001869 | regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869) |
| 0.0 | 1.7 | GO:0046676 | negative regulation of insulin secretion(GO:0046676) |
| 0.1 | 1.5 | GO:0031987 | locomotion involved in locomotory behavior(GO:0031987) |
| 0.1 | 0.8 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
| 0.0 | 0.8 | GO:0071391 | cellular response to estrogen stimulus(GO:0071391) |
| 0.1 | 0.5 | GO:0070859 | positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253) |
| 0.0 | 0.5 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
| 0.0 | 0.4 | GO:0060484 | male sex determination(GO:0030238) lung-associated mesenchyme development(GO:0060484) |
| 0.0 | 0.4 | GO:0007216 | G-protein coupled glutamate receptor signaling pathway(GO:0007216) |
| 0.0 | 0.4 | GO:0015813 | L-glutamate transport(GO:0015813) |
| 0.1 | 0.3 | GO:0046013 | regulation of T cell homeostatic proliferation(GO:0046013) negative regulation of T-helper 17 type immune response(GO:2000317) regulation of T-helper 17 cell differentiation(GO:2000319) negative regulation of T-helper 17 cell differentiation(GO:2000320) |
| 0.0 | 0.2 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 0.0 | 0.2 | GO:0036444 | calcium ion transmembrane import into mitochondrion(GO:0036444) |
| 0.0 | 0.2 | GO:0032693 | negative regulation of interleukin-10 production(GO:0032693) |
| 0.0 | 0.1 | GO:2000195 | negative regulation of female gonad development(GO:2000195) |
| 0.0 | 0.1 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
Gene overrepresentation in cellular_component category:
Showing 1 to 8 of 8 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.9 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.1 | 0.9 | GO:0097427 | microtubule bundle(GO:0097427) |
| 0.0 | 0.5 | GO:0030061 | mitochondrial crista(GO:0030061) |
| 0.1 | 0.4 | GO:0097450 | astrocyte end-foot(GO:0097450) |
| 0.0 | 0.4 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.0 | 0.2 | GO:1990246 | uniplex complex(GO:1990246) |
| 0.0 | 0.1 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.0 | 0.1 | GO:0008091 | spectrin(GO:0008091) |
Gene overrepresentation in molecular_function category:
Showing 1 to 10 of 10 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 4.9 | GO:0001848 | complement binding(GO:0001848) |
| 0.0 | 1.7 | GO:0019905 | syntaxin binding(GO:0019905) |
| 0.2 | 1.5 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
| 0.0 | 0.5 | GO:0017127 | cholesterol transporter activity(GO:0017127) |
| 0.1 | 0.4 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
| 0.1 | 0.4 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
| 0.0 | 0.4 | GO:0005313 | L-glutamate transmembrane transporter activity(GO:0005313) |
| 0.0 | 0.4 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.1 | 0.3 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |
| 0.1 | 0.2 | GO:0004769 | steroid delta-isomerase activity(GO:0004769) |
Gene overrepresentation in C2:CP category:
Showing 1 to 3 of 3 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.9 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 1.7 | PID_TCR_CALCIUM_PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.0 | 0.8 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 3 of 3 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 4.9 | REACTOME_INTRINSIC_PATHWAY | Genes involved in Intrinsic Pathway |
| 0.0 | 0.5 | REACTOME_STEROID_HORMONES | Genes involved in Steroid hormones |
| 0.0 | 0.4 | REACTOME_FGFR4_LIGAND_BINDING_AND_ACTIVATION | Genes involved in FGFR4 ligand binding and activation |
