Motif ID: Hoxb6

Z-value: 0.205


Transcription factors associated with Hoxb6:

Gene SymbolEntrez IDGene Name
Hoxb6 ENSMUSG00000000690.4 Hoxb6



Activity profile for motif Hoxb6.

activity profile for motif Hoxb6


Sorted Z-values histogram for motif Hoxb6

Sorted Z-values for motif Hoxb6



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxb6

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_23248264 1.762 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr2_+_164769892 0.631 ENSMUST00000088248.6
ENSMUST00000001439.6
 Ube2c

ubiquitin-conjugating enzyme E2C

chr4_+_15881255 0.575 ENSMUST00000029876.1
 Calb1
calbindin 1
chr8_-_105471481 0.408 ENSMUST00000014990.6
 Tppp3
tubulin polymerization-promoting protein family member 3
chr2_-_125859139 0.355 ENSMUST00000110463.1
ENSMUST00000028635.5
 Cops2

COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana)

chr9_-_70141484 0.333 ENSMUST00000034749.8
 Fam81a
family with sequence similarity 81, member A
chr2_+_125859134 0.307 ENSMUST00000028636.6
ENSMUST00000125084.1
 Galk2

galactokinase 2

chr13_-_92030897 0.294 ENSMUST00000149630.1
 Rasgrf2
RAS protein-specific guanine nucleotide-releasing factor 2
chr6_-_3494587 0.287 ENSMUST00000049985.8
 Hepacam2
HEPACAM family member 2
chr7_+_51880312 0.270 ENSMUST00000145049.1
 Gas2
growth arrest specific 2
chr19_+_25406661 0.261 ENSMUST00000146647.1
 Kank1
KN motif and ankyrin repeat domains 1
chr9_-_35570393 0.246 ENSMUST00000115110.4
 Hyls1
hydrolethalus syndrome 1
chr8_-_77610597 0.239 ENSMUST00000034030.8
 Tmem184c
transmembrane protein 184C
chr5_+_88583527 0.235 ENSMUST00000031229.6
 Rufy3
RUN and FYVE domain containing 3
chr9_+_92309362 0.229 ENSMUST00000098477.1
ENSMUST00000150594.1
 1700057G04Rik

RIKEN cDNA 1700057G04 gene

chrX_-_143933204 0.223 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
 Dcx


doublecortin


chr19_+_24875679 0.192 ENSMUST00000073080.5
 Gm10053
predicted gene 10053
chr11_-_74724670 0.173 ENSMUST00000021091.8
 Pafah1b1
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chr6_+_142413441 0.159 ENSMUST00000088263.4
 B230216G23Rik
RIKEN cDNA B230216G23 gene
chr2_+_29346803 0.147 ENSMUST00000028139.4
ENSMUST00000113830.4
 Med27

mediator complex subunit 27

chr13_+_93304799 0.145 ENSMUST00000080127.5
 Homer1
homer homolog 1 (Drosophila)
chr8_-_77610668 0.142 ENSMUST00000141202.1
ENSMUST00000152168.1
 Tmem184c

transmembrane protein 184C

chr11_-_72215592 0.137 ENSMUST00000021157.8
 Med31
mediator of RNA polymerase II transcription, subunit 31 homolog (yeast)
chr8_-_54724474 0.124 ENSMUST00000175915.1
 Wdr17
WD repeat domain 17
chr3_+_94413244 0.119 ENSMUST00000166032.1
ENSMUST00000045245.5
 Tdrkh

tudor and KH domain containing protein

chr14_+_32599922 0.101 ENSMUST00000068938.5
 Prrxl1
paired related homeobox protein-like 1
chr19_-_6925367 0.096 ENSMUST00000057716.4
 Tex40
testis expressed 40
chrX_+_38600626 0.095 ENSMUST00000000365.2
 Mcts1
malignant T cell amplified sequence 1
chr8_+_31111816 0.093 ENSMUST00000046941.7
 Rnf122
ring finger protein 122
chrX_-_101222426 0.092 ENSMUST00000120389.1
ENSMUST00000156473.1
ENSMUST00000077876.3
 Snx12


sorting nexin 12


chr16_+_44347121 0.084 ENSMUST00000050897.6
 Spice1
spindle and centriole associated protein 1
chr6_+_86371489 0.078 ENSMUST00000089558.5
 Snrpg
small nuclear ribonucleoprotein polypeptide G
chr13_+_93304066 0.078 ENSMUST00000109493.1
 Homer1
homer homolog 1 (Drosophila)
chr6_-_12109583 0.076 ENSMUST00000080891.5
 Gm6578
predicted gene 6578
chr8_+_13435459 0.073 ENSMUST00000167071.1
ENSMUST00000167505.1
 Tmem255b

transmembrane protein 255B

chr3_-_119783262 0.068 ENSMUST00000029780.7
 Ptbp2
polypyrimidine tract binding protein 2
chr13_-_21810190 0.055 ENSMUST00000110469.1
ENSMUST00000091749.2
 Hist1h2bq

histone cluster 1, H2bq

chr4_-_134853294 0.049 ENSMUST00000030628.8
 Tmem57
transmembrane protein 57
chr12_+_103388656 0.046 ENSMUST00000101094.2
ENSMUST00000021620.6
 Otub2

OTU domain, ubiquitin aldehyde binding 2

chrX_-_143933089 0.045 ENSMUST00000087313.3
 Dcx
doublecortin
chrX_-_8252304 0.040 ENSMUST00000115594.1
 Ftsj1
FtsJ homolog 1 (E. coli)
chr5_+_31526989 0.036 ENSMUST00000114533.2
ENSMUST00000117262.1
ENSMUST00000117319.1
 Slc4a1ap


solute carrier family 4 (anion exchanger), member 1, adaptor protein


chr5_-_31526693 0.007 ENSMUST00000118874.1
ENSMUST00000117642.1
ENSMUST00000065388.4
 Supt7l


suppressor of Ty 7-like


chr11_-_96977660 0.005 ENSMUST00000107626.1
ENSMUST00000107624.1
 Sp2

Sp2 transcription factor

chr3_-_100969644 0.004 ENSMUST00000076941.5
 Ttf2
transcription termination factor, RNA polymerase II
chr8_+_111033890 0.003 ENSMUST00000034441.7
 Aars
alanyl-tRNA synthetase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.8 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.6 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.1 0.6 GO:0072235 distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235)
0.1 0.3 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.2 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.2 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.1 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.0 0.3 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.4 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.1 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.3 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.2 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.3 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.2 GO:0000235 astral microtubule(GO:0000235)
0.0 0.2 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.2 GO:0071437 invadopodium(GO:0071437)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0004335 galactokinase activity(GO:0004335)
0.0 0.2 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.4 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.3 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.3 REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor