Motif ID: Hoxb6

Z-value: 0.205


Transcription factors associated with Hoxb6:

Gene SymbolEntrez IDGene Name
Hoxb6 ENSMUSG00000000690.4 Hoxb6



Activity profile for motif Hoxb6.

activity profile for motif Hoxb6


Sorted Z-values histogram for motif Hoxb6

Sorted Z-values for motif Hoxb6



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxb6

PNG image of the network

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Top targets:


Showing 1 to 20 of 46 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 1.762 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr2_+_164769892 0.631 ENSMUST00000088248.6
ENSMUST00000001439.6
 Ube2c

ubiquitin-conjugating enzyme E2C

chr4_+_15881255 0.575 ENSMUST00000029876.1
 Calb1
calbindin 1
chr8_-_105471481 0.408 ENSMUST00000014990.6
 Tppp3
tubulin polymerization-promoting protein family member 3
chr2_-_125859139 0.355 ENSMUST00000110463.1
ENSMUST00000028635.5
 Cops2

COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana)

chr9_-_70141484 0.333 ENSMUST00000034749.8
 Fam81a
family with sequence similarity 81, member A
chr2_+_125859134 0.307 ENSMUST00000028636.6
ENSMUST00000125084.1
 Galk2

galactokinase 2

chr13_-_92030897 0.294 ENSMUST00000149630.1
 Rasgrf2
RAS protein-specific guanine nucleotide-releasing factor 2
chr6_-_3494587 0.287 ENSMUST00000049985.8
 Hepacam2
HEPACAM family member 2
chr7_+_51880312 0.270 ENSMUST00000145049.1
 Gas2
growth arrest specific 2
chr19_+_25406661 0.261 ENSMUST00000146647.1
 Kank1
KN motif and ankyrin repeat domains 1
chr9_-_35570393 0.246 ENSMUST00000115110.4
 Hyls1
hydrolethalus syndrome 1
chr8_-_77610597 0.239 ENSMUST00000034030.8
 Tmem184c
transmembrane protein 184C
chr5_+_88583527 0.235 ENSMUST00000031229.6
 Rufy3
RUN and FYVE domain containing 3
chr9_+_92309362 0.229 ENSMUST00000098477.1
ENSMUST00000150594.1
 1700057G04Rik

RIKEN cDNA 1700057G04 gene

chrX_-_143933204 0.223 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
 Dcx


doublecortin


chr19_+_24875679 0.192 ENSMUST00000073080.5
 Gm10053
predicted gene 10053
chr11_-_74724670 0.173 ENSMUST00000021091.8
 Pafah1b1
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chr6_+_142413441 0.159 ENSMUST00000088263.4
 B230216G23Rik
RIKEN cDNA B230216G23 gene
chr2_+_29346803 0.147 ENSMUST00000028139.4
ENSMUST00000113830.4
 Med27

mediator complex subunit 27


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 1.8 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.6 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.1 0.6 GO:0072235 distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235)
0.0 0.4 GO:0000338 protein deneddylation(GO:0000338)
0.1 0.3 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.3 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.3 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.3 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 0.2 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.2 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.2 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.1 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.1 GO:0034587 piRNA metabolic process(GO:0034587)

Gene overrepresentation in cellular_component category:

Showing 1 to 6 of 6 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.4 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.2 GO:0000235 astral microtubule(GO:0000235)
0.0 0.2 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.2 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)

Gene overrepresentation in molecular_function category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 0.3 GO:0004335 galactokinase activity(GO:0004335)
0.0 0.2 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)

Gene overrepresentation in C2:CP category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.4 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.3 ST_G_ALPHA_S_PATHWAY G alpha s Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.6 REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.3 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.3 REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor