Motif ID: Hoxb7

Z-value: 3.363


Transcription factors associated with Hoxb7:

Gene SymbolEntrez IDGene Name
Hoxb7 ENSMUSG00000038721.8 Hoxb7



Activity profile for motif Hoxb7.

activity profile for motif Hoxb7


Sorted Z-values histogram for motif Hoxb7

Sorted Z-values for motif Hoxb7



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxb7

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_+_83504032 54.971 ENSMUST00000163888.1
ENSMUST00000005722.7
Mef2c

myocyte enhancer factor 2C

chr8_+_54954728 38.924 ENSMUST00000033915.7
Gpm6a
glycoprotein m6a
chrX_-_43167817 38.763 ENSMUST00000115058.1
ENSMUST00000115059.1
Tenm1

teneurin transmembrane protein 1

chr4_+_102589687 38.256 ENSMUST00000097949.4
ENSMUST00000106901.1
Pde4b

phosphodiesterase 4B, cAMP specific

chr6_-_13839916 37.940 ENSMUST00000060442.7
Gpr85
G protein-coupled receptor 85
chr15_+_21111452 36.812 ENSMUST00000075132.6
Cdh12
cadherin 12
chr6_-_136171722 35.188 ENSMUST00000053880.6
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr2_+_65930117 31.952 ENSMUST00000176109.1
Csrnp3
cysteine-serine-rich nuclear protein 3
chr19_+_26749726 31.688 ENSMUST00000175842.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr19_+_26605106 31.465 ENSMUST00000025862.7
ENSMUST00000176030.1
Smarca2

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2

chr19_+_26750939 30.122 ENSMUST00000175953.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr3_+_55461758 29.633 ENSMUST00000070418.4
Dclk1
doublecortin-like kinase 1
chr11_-_30198232 29.438 ENSMUST00000102838.3
Sptbn1
spectrin beta, non-erythrocytic 1
chr1_-_56969827 28.580 ENSMUST00000176759.1
Satb2
special AT-rich sequence binding protein 2
chr13_+_42680565 28.462 ENSMUST00000128646.1
Phactr1
phosphatase and actin regulator 1
chr17_-_81649607 27.191 ENSMUST00000163680.2
ENSMUST00000086538.3
ENSMUST00000163123.1
Slc8a1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr1_-_56969864 27.040 ENSMUST00000177424.1
Satb2
special AT-rich sequence binding protein 2
chr19_-_28911879 26.921 ENSMUST00000179171.1
AC163993.1
AC163993.1
chr2_-_7396192 26.878 ENSMUST00000137733.2
Celf2
CUGBP, Elav-like family member 2
chr7_+_91090697 26.710 ENSMUST00000107196.2
Dlg2
discs, large homolog 2 (Drosophila)
chr16_+_7069825 26.168 ENSMUST00000056416.7
Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr7_+_91090728 26.127 ENSMUST00000074273.3
Dlg2
discs, large homolog 2 (Drosophila)
chr13_+_42681513 25.813 ENSMUST00000149235.1
Phactr1
phosphatase and actin regulator 1
chr5_+_117841839 25.551 ENSMUST00000142742.2
Nos1
nitric oxide synthase 1, neuronal
chr9_-_112187766 25.333 ENSMUST00000111872.2
ENSMUST00000164754.2
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr12_-_31713873 24.875 ENSMUST00000057783.4
ENSMUST00000174480.2
ENSMUST00000176710.1
Gpr22


G protein-coupled receptor 22


chr15_+_92597104 24.711 ENSMUST00000035399.8
Pdzrn4
PDZ domain containing RING finger 4
chr1_+_159737510 24.278 ENSMUST00000111669.3
Tnr
tenascin R
chr4_+_13751297 24.231 ENSMUST00000105566.2
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr12_+_29528382 23.858 ENSMUST00000049784.9
Myt1l
myelin transcription factor 1-like
chr2_-_7395879 23.730 ENSMUST00000182404.1
Celf2
CUGBP, Elav-like family member 2
chr1_+_19103022 22.879 ENSMUST00000037294.7
Tfap2d
transcription factor AP-2, delta
chr2_+_65620829 22.851 ENSMUST00000028377.7
Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr8_-_109251698 22.783 ENSMUST00000079189.3
4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr1_+_66321708 22.672 ENSMUST00000114013.1
Map2
microtubule-associated protein 2
chr17_-_90088343 22.052 ENSMUST00000173917.1
Nrxn1
neurexin I
chr4_+_101507947 21.870 ENSMUST00000149047.1
ENSMUST00000106929.3
Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr11_-_37235882 21.789 ENSMUST00000102801.1
Tenm2
teneurin transmembrane protein 2
chr10_-_109009055 21.359 ENSMUST00000156979.1
Syt1
synaptotagmin I
chr2_+_37516618 21.240 ENSMUST00000065441.6
Gpr21
G protein-coupled receptor 21
chr1_+_34005872 21.190 ENSMUST00000182296.1
Dst
dystonin
chr9_-_40346290 21.089 ENSMUST00000121357.1
Gramd1b
GRAM domain containing 1B
chr9_-_29963112 20.982 ENSMUST00000075069.4
Ntm
neurotrimin
chr9_-_112187898 20.784 ENSMUST00000178410.1
ENSMUST00000172380.3
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr13_+_16014457 20.781 ENSMUST00000164993.1
Inhba
inhibin beta-A
chr17_+_3397189 20.500 ENSMUST00000072156.6
Tiam2
T cell lymphoma invasion and metastasis 2
chr3_-_26133734 20.217 ENSMUST00000108308.3
ENSMUST00000075054.4
Nlgn1

neuroligin 1

chr6_-_13838432 19.791 ENSMUST00000115492.1
Gpr85
G protein-coupled receptor 85
chr15_+_18818895 19.727 ENSMUST00000166873.2
Cdh10
cadherin 10
chr6_+_96113146 19.701 ENSMUST00000122120.1
Fam19a1
family with sequence similarity 19, member A1
chr2_-_45112890 19.672 ENSMUST00000076836.6
Zeb2
zinc finger E-box binding homeobox 2
chr1_+_177445660 19.590 ENSMUST00000077225.6
Zbtb18
zinc finger and BTB domain containing 18
chr10_-_64090265 19.139 ENSMUST00000105439.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr2_+_68104671 19.133 ENSMUST00000042456.3
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr15_-_66812593 19.090 ENSMUST00000100572.3
Sla
src-like adaptor
chr2_-_7081207 19.038 ENSMUST00000114923.2
ENSMUST00000182706.1
Celf2

CUGBP, Elav-like family member 2

chr5_+_19907774 18.869 ENSMUST00000115267.2
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr3_+_68572245 18.808 ENSMUST00000170788.2
Schip1
schwannomin interacting protein 1
chr2_-_6884940 18.730 ENSMUST00000183091.1
ENSMUST00000182851.1
Celf2

CUGBP, Elav-like family member 2

chr3_+_18054258 18.658 ENSMUST00000026120.6
Bhlhe22
basic helix-loop-helix family, member e22
chrX_-_143933089 18.559 ENSMUST00000087313.3
Dcx
doublecortin
chrX_-_43274786 18.397 ENSMUST00000016294.7
Tenm1
teneurin transmembrane protein 1
chr1_+_81077274 18.178 ENSMUST00000068275.5
ENSMUST00000113494.2
Nyap2

neuronal tyrosine-phophorylated phosphoinositide 3-kinase adaptor 2

chr13_+_42866247 17.773 ENSMUST00000131942.1
Phactr1
phosphatase and actin regulator 1
chr4_-_35845204 17.759 ENSMUST00000164772.1
ENSMUST00000065173.2
Lingo2

leucine rich repeat and Ig domain containing 2

chr17_+_70561739 17.748 ENSMUST00000097288.2
Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr1_+_179961110 17.560 ENSMUST00000076687.5
ENSMUST00000097450.3
Cdc42bpa

CDC42 binding protein kinase alpha

chr6_+_80018877 17.142 ENSMUST00000147663.1
ENSMUST00000128718.1
ENSMUST00000126005.1
ENSMUST00000133918.1
Lrrtm4



leucine rich repeat transmembrane neuronal 4



chr14_+_101840501 17.108 ENSMUST00000159026.1
Lmo7
LIM domain only 7
chr3_+_55782500 16.892 ENSMUST00000075422.4
Mab21l1
mab-21-like 1 (C. elegans)
chr13_+_109926832 16.868 ENSMUST00000117420.1
Pde4d
phosphodiesterase 4D, cAMP specific
chr16_+_43247278 16.821 ENSMUST00000114691.1
ENSMUST00000079441.6
Zbtb20

zinc finger and BTB domain containing 20

chr3_-_146770218 16.658 ENSMUST00000106137.1
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr14_-_93888732 16.653 ENSMUST00000068992.2
Pcdh9
protocadherin 9
chr1_-_79440039 16.623 ENSMUST00000049972.4
Scg2
secretogranin II
chr10_-_64090241 16.468 ENSMUST00000133588.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr1_-_126830632 16.445 ENSMUST00000112583.1
ENSMUST00000094609.3
Nckap5

NCK-associated protein 5

chr5_+_66968559 16.411 ENSMUST00000127184.1
Limch1
LIM and calponin homology domains 1
chr19_+_26748268 16.264 ENSMUST00000175791.1
ENSMUST00000176698.1
ENSMUST00000177252.1
ENSMUST00000176475.1
ENSMUST00000112637.2
Smarca2




SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2




chr9_-_49798905 16.174 ENSMUST00000114476.2
Ncam1
neural cell adhesion molecule 1
chr10_-_109010955 16.087 ENSMUST00000105276.1
ENSMUST00000064054.7
Syt1

synaptotagmin I

chr10_+_69787431 16.029 ENSMUST00000183240.1
Ank3
ankyrin 3, epithelial
chr2_-_65567505 15.790 ENSMUST00000100069.2
Scn3a
sodium channel, voltage-gated, type III, alpha
chr6_+_80019008 15.770 ENSMUST00000126399.1
ENSMUST00000136421.1
Lrrtm4

leucine rich repeat transmembrane neuronal 4

chr11_+_31872100 15.712 ENSMUST00000020543.6
ENSMUST00000109412.2
Cpeb4

cytoplasmic polyadenylation element binding protein 4

chr5_+_107497762 15.627 ENSMUST00000152474.1
ENSMUST00000060553.7
A830010M20Rik

RIKEN cDNA A830010M20 gene

chr9_+_32116040 15.416 ENSMUST00000174641.1
Arhgap32
Rho GTPase activating protein 32
chr14_-_124677089 15.197 ENSMUST00000095529.3
Fgf14
fibroblast growth factor 14
chr11_-_42000834 15.135 ENSMUST00000070725.4
Gabrg2
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr2_-_64975762 15.072 ENSMUST00000156765.1
Grb14
growth factor receptor bound protein 14
chr4_+_108719649 15.026 ENSMUST00000178992.1
3110021N24Rik
RIKEN cDNA 3110021N24 gene
chr3_+_26331150 14.907 ENSMUST00000099182.2
A830092H15Rik
RIKEN cDNA A830092H15 gene
chr4_+_101507855 14.897 ENSMUST00000038207.5
Dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr2_-_7081256 14.729 ENSMUST00000183209.1
Celf2
CUGBP, Elav-like family member 2
chr14_-_36935560 14.687 ENSMUST00000183038.1
Ccser2
coiled-coil serine rich 2
chr4_+_5724304 14.514 ENSMUST00000108380.1
Fam110b
family with sequence similarity 110, member B
chr1_+_66322102 14.478 ENSMUST00000123647.1
Map2
microtubule-associated protein 2
chr14_+_101840602 14.457 ENSMUST00000159314.1
Lmo7
LIM domain only 7
chr17_+_70522083 14.397 ENSMUST00000148486.1
ENSMUST00000133717.1
Dlgap1

discs, large (Drosophila) homolog-associated protein 1

chr11_-_76509419 14.339 ENSMUST00000094012.4
Abr
active BCR-related gene
chr2_+_61804453 14.335 ENSMUST00000048934.8
Tbr1
T-box brain gene 1
chr1_-_56971762 14.286 ENSMUST00000114415.3
Satb2
special AT-rich sequence binding protein 2
chr13_+_76579670 14.282 ENSMUST00000126960.1
ENSMUST00000109583.2
Mctp1

multiple C2 domains, transmembrane 1

chr6_-_118780324 14.200 ENSMUST00000112793.3
ENSMUST00000075591.6
ENSMUST00000078320.7
ENSMUST00000112790.2
Cacna1c



calcium channel, voltage-dependent, L type, alpha 1C subunit



chr3_-_146770603 14.173 ENSMUST00000106138.1
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr13_-_84064772 14.159 ENSMUST00000182477.1
Gm17750
predicted gene, 17750
chr10_+_69534208 14.134 ENSMUST00000182439.1
ENSMUST00000092434.5
ENSMUST00000092432.5
ENSMUST00000092431.5
ENSMUST00000054167.8
ENSMUST00000047061.6
Ank3





ankyrin 3, epithelial





chr15_-_48791933 14.034 ENSMUST00000160658.1
ENSMUST00000100670.3
ENSMUST00000162830.1
Csmd3


CUB and Sushi multiple domains 3


chr9_-_49798729 13.986 ENSMUST00000166811.2
Ncam1
neural cell adhesion molecule 1
chr1_+_34121250 13.724 ENSMUST00000183006.1
Dst
dystonin
chr1_+_177444653 13.660 ENSMUST00000094276.3
Zbtb18
zinc finger and BTB domain containing 18
chr11_-_42000532 13.582 ENSMUST00000070735.3
Gabrg2
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr8_-_8639363 13.513 ENSMUST00000152698.1
Efnb2
ephrin B2
chr1_+_81077204 13.444 ENSMUST00000123720.1
Nyap2
neuronal tyrosine-phophorylated phosphoinositide 3-kinase adaptor 2
chr3_+_13946368 13.439 ENSMUST00000171075.1
ENSMUST00000108372.2
Ralyl

RALY RNA binding protein-like

chr1_-_56978534 13.364 ENSMUST00000177282.1
Satb2
special AT-rich sequence binding protein 2
chr1_-_155417394 13.342 ENSMUST00000111775.1
ENSMUST00000111774.1
Xpr1

xenotropic and polytropic retrovirus receptor 1

chr8_-_54718664 13.271 ENSMUST00000144711.2
ENSMUST00000093510.2
Wdr17

WD repeat domain 17

chr8_+_66386292 13.178 ENSMUST00000039540.5
ENSMUST00000110253.2
March1

membrane-associated ring finger (C3HC4) 1

chr10_+_90576252 13.161 ENSMUST00000182427.1
ENSMUST00000182053.1
ENSMUST00000182113.1
Anks1b


ankyrin repeat and sterile alpha motif domain containing 1B


chr13_-_101692624 13.158 ENSMUST00000035532.6
Pik3r1
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)
chr19_-_57239310 13.042 ENSMUST00000111559.1
Ablim1
actin-binding LIM protein 1
chr2_-_6721890 13.042 ENSMUST00000114927.2
Celf2
CUGBP, Elav-like family member 2
chr6_-_97459279 13.018 ENSMUST00000113359.1
Frmd4b
FERM domain containing 4B
chr2_-_65567465 12.993 ENSMUST00000066432.5
Scn3a
sodium channel, voltage-gated, type III, alpha
chr5_+_107497718 12.910 ENSMUST00000112671.2
A830010M20Rik
RIKEN cDNA A830010M20 gene
chr5_-_23616528 12.876 ENSMUST00000088392.4
Srpk2
serine/arginine-rich protein specific kinase 2
chr15_-_77153772 12.842 ENSMUST00000166610.1
ENSMUST00000111581.2
Rbfox2

RNA binding protein, fox-1 homolog (C. elegans) 2

chr2_-_7395968 12.820 ENSMUST00000002176.6
Celf2
CUGBP, Elav-like family member 2
chr18_+_36952621 12.767 ENSMUST00000115661.2
Pcdha2
protocadherin alpha 2
chr14_-_36919314 12.637 ENSMUST00000182797.1
Ccser2
coiled-coil serine rich 2
chr18_-_31447383 12.440 ENSMUST00000025110.3
Syt4
synaptotagmin IV
chr5_+_66968961 12.378 ENSMUST00000132991.1
Limch1
LIM and calponin homology domains 1
chr15_+_92161343 12.341 ENSMUST00000068378.5
Cntn1
contactin 1
chrX_+_159708593 12.331 ENSMUST00000080394.6
Sh3kbp1
SH3-domain kinase binding protein 1
chr1_+_66386968 12.327 ENSMUST00000145419.1
Map2
microtubule-associated protein 2
chr8_+_65967157 12.269 ENSMUST00000072482.6
March1
membrane-associated ring finger (C3HC4) 1
chr16_-_23988852 12.113 ENSMUST00000023151.5
Bcl6
B cell leukemia/lymphoma 6
chr1_-_25228814 12.036 ENSMUST00000126626.1
Bai3
brain-specific angiogenesis inhibitor 3
chr3_+_28263205 11.988 ENSMUST00000159236.2
Tnik
TRAF2 and NCK interacting kinase
chr1_-_126830786 11.935 ENSMUST00000162646.1
Nckap5
NCK-associated protein 5
chr4_+_119814495 11.903 ENSMUST00000106307.2
Hivep3
human immunodeficiency virus type I enhancer binding protein 3
chrX_-_143933204 11.639 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chr4_+_102421518 11.623 ENSMUST00000106904.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr10_+_69706326 11.621 ENSMUST00000182992.1
Ank3
ankyrin 3, epithelial
chr1_-_132707304 11.617 ENSMUST00000043189.7
Nfasc
neurofascin
chr10_+_69925954 11.599 ENSMUST00000181974.1
ENSMUST00000182795.1
ENSMUST00000182437.1
Ank3


ankyrin 3, epithelial


chr11_-_42000284 11.594 ENSMUST00000109292.2
ENSMUST00000109290.1
Gabrg2

gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2

chr17_+_70522149 11.584 ENSMUST00000140728.1
Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr6_-_126166726 11.454 ENSMUST00000112244.2
ENSMUST00000050484.7
Ntf3

neurotrophin 3

chr16_+_42907563 11.377 ENSMUST00000151244.1
ENSMUST00000114694.2
Zbtb20

zinc finger and BTB domain containing 20

chr10_+_69925484 11.317 ENSMUST00000182692.1
ENSMUST00000092433.5
Ank3

ankyrin 3, epithelial

chrX_-_165327376 11.289 ENSMUST00000058787.8
Glra2
glycine receptor, alpha 2 subunit
chr7_-_120202104 11.268 ENSMUST00000033198.5
Crym
crystallin, mu
chr13_+_83573577 11.251 ENSMUST00000185052.1
Mef2c
myocyte enhancer factor 2C
chr2_+_4300462 11.245 ENSMUST00000175669.1
Frmd4a
FERM domain containing 4A
chr4_-_88033328 11.223 ENSMUST00000078090.5
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr2_-_6722187 11.147 ENSMUST00000182657.1
Celf2
CUGBP, Elav-like family member 2
chr10_+_99263224 11.147 ENSMUST00000020118.4
Dusp6
dual specificity phosphatase 6
chr13_+_16011851 11.138 ENSMUST00000042603.6
Inhba
inhibin beta-A
chr15_-_66831625 11.077 ENSMUST00000164163.1
Sla
src-like adaptor
chr2_+_96318014 11.066 ENSMUST00000135431.1
ENSMUST00000162807.2
Lrrc4c

leucine rich repeat containing 4C

chr5_+_81021202 11.036 ENSMUST00000117253.1
ENSMUST00000120128.1
Lphn3

latrophilin 3

chr10_+_69925766 11.016 ENSMUST00000182269.1
ENSMUST00000183261.1
ENSMUST00000183074.1
Ank3


ankyrin 3, epithelial


chr16_-_97170707 11.015 ENSMUST00000056102.7
Dscam
Down syndrome cell adhesion molecule
chr14_-_108914237 10.949 ENSMUST00000100322.2
Slitrk1
SLIT and NTRK-like family, member 1
chr5_+_66968416 10.938 ENSMUST00000038188.7
Limch1
LIM and calponin homology domains 1
chr1_-_38821215 10.911 ENSMUST00000039612.4
Lonrf2
LON peptidase N-terminal domain and ring finger 2
chr9_-_75597643 10.869 ENSMUST00000164100.1
Tmod2
tropomodulin 2
chr18_+_23415400 10.840 ENSMUST00000115832.2
ENSMUST00000047954.7
Dtna

dystrobrevin alpha

chr5_+_19907502 10.820 ENSMUST00000101558.3
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr8_-_54724474 10.774 ENSMUST00000175915.1
Wdr17
WD repeat domain 17
chr18_+_37496997 10.696 ENSMUST00000059571.5
Pcdhb19
protocadherin beta 19
chr19_-_37176055 10.598 ENSMUST00000142973.1
ENSMUST00000154376.1
Cpeb3

cytoplasmic polyadenylation element binding protein 3

chr4_+_42922253 10.547 ENSMUST00000139100.1
N28178
expressed sequence N28178
chr8_-_41016749 10.493 ENSMUST00000117735.1
Mtus1
mitochondrial tumor suppressor 1
chr10_+_106470281 10.343 ENSMUST00000029404.9
ENSMUST00000169303.1
Ppfia2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr5_-_66514815 10.288 ENSMUST00000161879.1
ENSMUST00000159357.1
Apbb2

amyloid beta (A4) precursor protein-binding, family B, member 2

chr7_+_126950518 10.218 ENSMUST00000106335.1
ENSMUST00000146017.1
Sez6l2

seizure related 6 homolog like 2

chrM_+_10167 10.074 ENSMUST00000082414.1
mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chrX_+_112615301 9.993 ENSMUST00000122805.1
Zfp711
zinc finger protein 711
chr1_-_158356258 9.927 ENSMUST00000004133.8
Brinp2
bone morphogenic protein/retinoic acid inducible neural-specific 2
chr18_-_22850738 9.904 ENSMUST00000092015.4
ENSMUST00000069215.6
Nol4

nucleolar protein 4

chr10_+_90576872 9.866 ENSMUST00000182550.1
ENSMUST00000099364.5
Anks1b

ankyrin repeat and sterile alpha motif domain containing 1B

chr2_-_104257400 9.826 ENSMUST00000141159.1
D430041D05Rik
RIKEN cDNA D430041D05 gene
chr10_+_69925800 9.820 ENSMUST00000182029.1
Ank3
ankyrin 3, epithelial
chr2_-_5676046 9.779 ENSMUST00000114987.3
Camk1d
calcium/calmodulin-dependent protein kinase ID
chr11_-_98053415 9.739 ENSMUST00000017544.2
Stac2
SH3 and cysteine rich domain 2
chr4_+_48049080 9.698 ENSMUST00000153369.1
Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr18_-_35215008 9.654 ENSMUST00000091636.3
Lrrtm2
leucine rich repeat transmembrane neuronal 2
chr16_-_92400067 9.619 ENSMUST00000023672.8
Rcan1
regulator of calcineurin 1
chr5_+_81021583 9.608 ENSMUST00000121707.1
Lphn3
latrophilin 3
chr4_-_116405986 9.603 ENSMUST00000123072.1
ENSMUST00000144281.1
Mast2

microtubule associated serine/threonine kinase 2

chr14_-_102982630 9.584 ENSMUST00000184744.1
KCTD12
mmu-mir-5130
chr9_+_113812547 9.568 ENSMUST00000166734.2
ENSMUST00000111838.2
ENSMUST00000163895.2
Clasp2


CLIP associating protein 2


chr13_+_93308006 9.513 ENSMUST00000079086.6
Homer1
homer homolog 1 (Drosophila)
chr9_+_40269273 9.510 ENSMUST00000176185.1
Scn3b
sodium channel, voltage-gated, type III, beta
chr9_-_112232449 9.496 ENSMUST00000035085.5
Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr1_-_37496095 9.491 ENSMUST00000148047.1
ENSMUST00000143636.1
Mgat4a

mannoside acetylglucosaminyltransferase 4, isoenzyme A

chr10_-_68278713 9.451 ENSMUST00000020106.7
Arid5b
AT rich interactive domain 5B (MRF1-like)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
22.1 66.2 GO:0007521 muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111)
15.3 45.8 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923)
12.2 109.5 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
10.6 42.4 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
10.1 30.2 GO:0001928 regulation of exocyst assembly(GO:0001928)
9.2 54.9 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
9.1 27.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
7.8 85.5 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
7.8 100.9 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
7.5 37.7 GO:0046684 response to pyrethroid(GO:0046684)
7.0 55.9 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
7.0 41.9 GO:0072318 clathrin coat disassembly(GO:0072318)
6.6 33.2 GO:0042701 progesterone secretion(GO:0042701)
6.0 17.9 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
5.9 53.5 GO:0098907 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907)
5.9 52.9 GO:0071420 cellular response to histamine(GO:0071420)
5.7 39.6 GO:0005513 detection of calcium ion(GO:0005513)
5.1 35.8 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
5.0 15.1 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
5.0 15.1 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
4.6 23.1 GO:0007256 activation of JNKK activity(GO:0007256)
4.6 64.5 GO:0045161 neuronal ion channel clustering(GO:0045161)
4.6 13.8 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
4.5 54.2 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
4.5 18.0 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
4.3 17.3 GO:2000481 positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
4.0 12.1 GO:0043379 regulation of mast cell cytokine production(GO:0032763) memory T cell differentiation(GO:0043379)
4.0 20.0 GO:0021856 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
3.9 38.7 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
3.9 23.1 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
3.9 50.1 GO:0070842 aggresome assembly(GO:0070842)
3.8 61.6 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
3.8 15.2 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
3.7 154.7 GO:0006376 mRNA splice site selection(GO:0006376)
3.7 11.0 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
3.6 14.2 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
3.5 10.6 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
3.5 28.1 GO:0086018 SA node cell action potential(GO:0086015) SA node cell to atrial cardiac muscle cell signalling(GO:0086018) SA node cell to atrial cardiac muscle cell communication(GO:0086070)
3.5 14.1 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
3.4 3.4 GO:0097324 melanocyte migration(GO:0097324)
3.3 13.4 GO:0038128 ERBB2 signaling pathway(GO:0038128)
3.3 16.6 GO:0048245 eosinophil chemotaxis(GO:0048245)
3.3 3.3 GO:1900127 positive regulation of hyaluronan biosynthetic process(GO:1900127)
3.2 12.7 GO:1904800 regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800)
3.1 9.4 GO:0050915 sensory perception of sour taste(GO:0050915)
3.1 25.1 GO:0097264 self proteolysis(GO:0097264)
3.1 12.3 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
3.0 30.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
2.9 8.7 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
2.9 14.3 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
2.9 17.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
2.9 8.6 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
2.8 47.2 GO:0097090 presynaptic membrane organization(GO:0097090)
2.8 8.3 GO:0003105 negative regulation of glomerular filtration(GO:0003105)
2.7 11.0 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
2.7 8.1 GO:0051964 negative regulation of synapse assembly(GO:0051964)
2.6 7.9 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
2.6 7.8 GO:1904978 regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980)
2.6 12.8 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
2.6 7.7 GO:0030210 heparin biosynthetic process(GO:0030210)
2.5 12.4 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
2.5 7.4 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
2.4 7.1 GO:0003289 septum primum development(GO:0003284) atrial septum primum morphogenesis(GO:0003289) noradrenergic neuron differentiation(GO:0003357)
2.3 35.1 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
2.3 18.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
2.3 31.9 GO:0055059 asymmetric neuroblast division(GO:0055059)
2.2 15.7 GO:0019532 oxalate transport(GO:0019532)
2.2 6.7 GO:0007525 somatic muscle development(GO:0007525)
2.2 6.6 GO:0035864 response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
2.1 15.0 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
2.1 4.3 GO:0061055 myotome development(GO:0061055)
2.1 16.8 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
2.1 10.3 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
2.0 10.2 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
2.0 14.2 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
2.0 6.0 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
2.0 9.8 GO:0035063 nuclear speck organization(GO:0035063)
1.9 44.7 GO:0008090 retrograde axonal transport(GO:0008090)
1.9 7.7 GO:0097494 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944) regulation of vesicle size(GO:0097494)
1.9 11.3 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
1.9 11.3 GO:0071361 cellular response to ethanol(GO:0071361)
1.9 28.0 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
1.8 64.7 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
1.8 25.9 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
1.8 5.5 GO:0019805 quinolinate biosynthetic process(GO:0019805)
1.8 7.3 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
1.8 1.8 GO:0046619 optic placode formation(GO:0001743) optic placode formation involved in camera-type eye formation(GO:0046619)
1.7 5.1 GO:0071415 cellular response to caffeine(GO:0071313) cellular response to purine-containing compound(GO:0071415)
1.7 13.5 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
1.7 6.7 GO:2000821 regulation of grooming behavior(GO:2000821)
1.7 13.3 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
1.7 3.3 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
1.6 9.9 GO:0051694 pointed-end actin filament capping(GO:0051694)
1.6 4.8 GO:0001543 ovarian follicle rupture(GO:0001543)
1.6 11.2 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
1.6 8.0 GO:0070327 thyroid hormone transport(GO:0070327)
1.6 18.8 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
1.6 3.1 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
1.6 12.5 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
1.6 6.2 GO:0060178 regulation of exocyst localization(GO:0060178)
1.5 4.5 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
1.5 9.0 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
1.5 15.0 GO:0015701 bicarbonate transport(GO:0015701)
1.5 7.4 GO:0006543 glutamine catabolic process(GO:0006543)
1.5 5.9 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
1.5 64.5 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
1.5 10.2 GO:0010459 negative regulation of heart rate(GO:0010459)
1.4 2.9 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
1.4 25.4 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
1.4 33.7 GO:0002091 negative regulation of receptor internalization(GO:0002091)
1.4 19.7 GO:0001553 luteinization(GO:0001553)
1.4 9.8 GO:0060267 positive regulation of respiratory burst(GO:0060267)
1.4 4.2 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
1.4 2.8 GO:0086042 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042)
1.4 5.5 GO:1901475 pyruvate transmembrane transport(GO:1901475)
1.4 5.5 GO:0044330 pyruvate transport(GO:0006848) canonical Wnt signaling pathway involved in positive regulation of wound healing(GO:0044330) lactic acid secretion(GO:0046722) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
1.4 5.4 GO:1904425 negative regulation of GTP binding(GO:1904425)
1.4 10.8 GO:0097475 motor neuron migration(GO:0097475)
1.3 8.0 GO:0098964 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
1.3 24.0 GO:0046069 cGMP catabolic process(GO:0046069)
1.3 34.5 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
1.3 2.5 GO:0002865 negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865)
1.3 78.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
1.2 5.0 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
1.2 6.2 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
1.2 3.7 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
1.2 1.2 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
1.2 7.3 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
1.2 12.1 GO:0061470 interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619)
1.2 2.4 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
1.2 3.6 GO:1901421 positive regulation of response to alcohol(GO:1901421)
1.2 26.4 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
1.2 4.7 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
1.2 5.8 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
1.2 3.5 GO:0007403 glial cell fate determination(GO:0007403)
1.2 23.2 GO:0007019 microtubule depolymerization(GO:0007019)
1.1 5.7 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
1.1 127.2 GO:0007416 synapse assembly(GO:0007416)
1.1 5.7 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
1.1 5.7 GO:0021592 fourth ventricle development(GO:0021592) initiation of neural tube closure(GO:0021993)
1.1 46.1 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
1.1 9.9 GO:0060613 fat pad development(GO:0060613)
1.1 14.2 GO:1902018 negative regulation of cilium assembly(GO:1902018)
1.1 52.2 GO:0034605 cellular response to heat(GO:0034605)
1.0 3.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
1.0 7.3 GO:0035095 behavioral response to nicotine(GO:0035095)
1.0 7.1 GO:0034058 endosomal vesicle fusion(GO:0034058)
1.0 5.0 GO:0060690 epithelial cell differentiation involved in salivary gland development(GO:0060690)
1.0 29.1 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
1.0 6.0 GO:0007258 JUN phosphorylation(GO:0007258)
1.0 7.9 GO:0048149 behavioral response to ethanol(GO:0048149)
1.0 2.9 GO:0017085 response to insecticide(GO:0017085)
0.9 9.0 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.9 2.7 GO:1904017 response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.9 5.3 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.9 3.5 GO:0001696 gastric acid secretion(GO:0001696)
0.9 2.6 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.9 2.6 GO:1900149 positive regulation of Schwann cell migration(GO:1900149)
0.8 3.4 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.8 2.5 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.8 9.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.8 7.4 GO:0032091 negative regulation of protein binding(GO:0032091)
0.8 2.5 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.8 4.0 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.8 4.9 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.8 5.6 GO:0098885 maternal process involved in parturition(GO:0060137) modification of postsynaptic actin cytoskeleton(GO:0098885)
0.8 4.0 GO:1905150 regulation of neuronal action potential(GO:0098908) regulation of voltage-gated sodium channel activity(GO:1905150)
0.8 5.5 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.8 3.8 GO:0060591 chondroblast differentiation(GO:0060591)
0.8 3.8 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.7 19.5 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.7 5.2 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.7 4.4 GO:0007021 tubulin complex assembly(GO:0007021)
0.7 5.2 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.7 5.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.7 5.1 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.7 9.5 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.7 6.5 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.7 7.7 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.7 2.8 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.7 4.1 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.7 2.1 GO:2000016 regulation of determination of dorsal identity(GO:2000015) negative regulation of determination of dorsal identity(GO:2000016)
0.7 2.8 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.7 4.8 GO:0010359 regulation of anion channel activity(GO:0010359)
0.7 2.7 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.7 28.1 GO:0001919 regulation of receptor recycling(GO:0001919)
0.7 3.3 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.7 1.3 GO:0048859 formation of anatomical boundary(GO:0048859)
0.7 7.9 GO:0006895 Golgi to endosome transport(GO:0006895)
0.6 1.3 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.6 3.2 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.6 1.9 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.6 7.1 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.6 22.3 GO:0045773 positive regulation of axon extension(GO:0045773)
0.6 2.5 GO:0006586 tryptophan metabolic process(GO:0006568) indolalkylamine metabolic process(GO:0006586)
0.6 7.0 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.6 10.7 GO:0048268 clathrin coat assembly(GO:0048268)
0.6 2.5 GO:0099527 postsynapse to nucleus signaling pathway(GO:0099527)
0.6 1.2 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.6 4.9 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.6 2.4 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) dibasic protein processing(GO:0090472) negative regulation of receptor catabolic process(GO:2000645)
0.6 2.4 GO:0060174 limb bud formation(GO:0060174)
0.6 8.9 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.6 16.4 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.6 0.6 GO:0070346 positive regulation of fat cell proliferation(GO:0070346)
0.6 5.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.6 0.6 GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion(GO:0010881)
0.6 1.1 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.6 4.0 GO:0007296 vitellogenesis(GO:0007296)
0.6 2.2 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.6 2.2 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.6 5.0 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.6 52.9 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.5 6.9 GO:0031507 heterochromatin assembly(GO:0031507)
0.5 5.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.5 4.0 GO:0042659 regulation of cell fate specification(GO:0042659)
0.5 2.9 GO:0034773 histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.5 2.5 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.5 1.0 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.5 2.9 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.5 1.9 GO:0034116 positive regulation of heterotypic cell-cell adhesion(GO:0034116)
0.5 0.9 GO:0060916 mesenchymal cell proliferation involved in lung development(GO:0060916)
0.5 6.6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.4 4.5 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.4 1.3 GO:0019389 glucuronoside metabolic process(GO:0019389)
0.4 22.2 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.4 2.7 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.4 4.4 GO:0010818 T cell chemotaxis(GO:0010818)
0.4 1.3 GO:0007028 cytoplasm organization(GO:0007028)
0.4 0.9 GO:0033625 positive regulation of integrin activation(GO:0033625)
0.4 1.7 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.4 29.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.4 8.5 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.4 3.4 GO:0042118 endothelial cell activation(GO:0042118)
0.4 0.8 GO:0089700 protein kinase D signaling(GO:0089700)
0.4 13.4 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.4 0.8 GO:1905154 negative regulation of membrane invagination(GO:1905154)
0.4 12.1 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.4 4.8 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.4 4.8 GO:0045793 positive regulation of cell size(GO:0045793)
0.4 10.4 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.4 2.8 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.4 2.4 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.4 3.9 GO:0046085 adenosine metabolic process(GO:0046085)
0.4 3.1 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.4 1.6 GO:0036089 cleavage furrow formation(GO:0036089)
0.4 2.3 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.4 0.8 GO:1905077 progesterone receptor signaling pathway(GO:0050847) negative regulation of interleukin-17 secretion(GO:1905077)
0.4 1.5 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.4 15.1 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.4 1.5 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.4 1.5 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780)
0.4 4.0 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.4 10.7 GO:0048536 spleen development(GO:0048536)
0.4 1.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.3 3.5 GO:0001961 positive regulation of cytokine-mediated signaling pathway(GO:0001961)
0.3 1.7 GO:0051684 maintenance of Golgi location(GO:0051684)
0.3 1.4 GO:1901380 negative regulation of potassium ion transmembrane transport(GO:1901380)
0.3 1.0 GO:0098886 modification of dendritic spine(GO:0098886)
0.3 1.7 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.3 1.4 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.3 4.7 GO:0001783 B cell apoptotic process(GO:0001783)
0.3 1.3 GO:0002188 translation reinitiation(GO:0002188)
0.3 8.9 GO:0043171 peptide catabolic process(GO:0043171)
0.3 5.2 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.3 6.8 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.3 4.2 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.3 12.6 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.3 5.5 GO:1903749 positive regulation of establishment of protein localization to mitochondrion(GO:1903749) positive regulation of protein targeting to mitochondrion(GO:1903955)
0.3 0.6 GO:2000508 regulation of dendritic cell chemotaxis(GO:2000508) positive regulation of dendritic cell chemotaxis(GO:2000510)
0.3 36.0 GO:0018210 peptidyl-threonine modification(GO:0018210)
0.3 1.8 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.3 1.2 GO:0033762 response to glucagon(GO:0033762)
0.3 1.2 GO:0035826 rubidium ion transport(GO:0035826) cellular hypotonic response(GO:0071476)
0.3 7.2 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.3 2.4 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.3 2.6 GO:0042572 retinol metabolic process(GO:0042572)
0.3 1.2 GO:0001887 selenium compound metabolic process(GO:0001887) selenocysteine metabolic process(GO:0016259)
0.3 1.1 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.3 5.3 GO:0046326 positive regulation of glucose import(GO:0046326)
0.3 1.1 GO:0050913 sensory perception of bitter taste(GO:0050913)
0.3 1.7 GO:0030242 pexophagy(GO:0030242)
0.3 1.4 GO:0097646 dimeric G-protein coupled receptor signaling pathway(GO:0038042) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.3 3.8 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.3 2.1 GO:2000232 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838) regulation of rRNA processing(GO:2000232) positive regulation of interleukin-6 secretion(GO:2000778)
0.3 2.7 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.3 18.8 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.3 13.0 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.3 2.1 GO:0006968 cellular defense response(GO:0006968)
0.3 10.3 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.3 2.6 GO:0007520 myoblast fusion(GO:0007520)
0.3 1.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.3 1.3 GO:0031424 keratinization(GO:0031424)
0.2 1.0 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.2 5.9 GO:0014037 Schwann cell differentiation(GO:0014037)
0.2 2.0 GO:0035608 protein deglutamylation(GO:0035608)
0.2 1.5 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.2 7.5 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.2 2.2 GO:0010793 regulation of mRNA export from nucleus(GO:0010793) regulation of ribonucleoprotein complex localization(GO:2000197)
0.2 1.0 GO:1901419 regulation of response to alcohol(GO:1901419)
0.2 0.7 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.2 0.7 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.2 3.0 GO:0014823 response to activity(GO:0014823)
0.2 3.7 GO:0021860 pyramidal neuron development(GO:0021860)
0.2 2.9 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.2 3.6 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.2 0.4 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.2 0.9 GO:0006953 acute-phase response(GO:0006953)
0.2 0.9 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.2 2.8 GO:0006622 protein targeting to lysosome(GO:0006622)
0.2 1.7 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.2 1.9 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 3.1 GO:0015809 arginine transport(GO:0015809)
0.2 2.7 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.2 1.0 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.2 0.8 GO:0045624 positive regulation of T-helper cell differentiation(GO:0045624)
0.2 1.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.2 0.8 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.2 2.8 GO:0072520 seminiferous tubule development(GO:0072520)
0.2 1.6 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.2 6.6 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.2 0.6 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.2 1.0 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.2 15.3 GO:0001578 microtubule bundle formation(GO:0001578)
0.2 1.1 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.2 2.5 GO:0007030 Golgi organization(GO:0007030)
0.2 2.3 GO:0035308 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.2 1.1 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.2 1.8 GO:0007602 phototransduction(GO:0007602)
0.2 14.5 GO:0050770 regulation of axonogenesis(GO:0050770)
0.2 0.9 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.2 2.0 GO:0030953 astral microtubule organization(GO:0030953)
0.2 1.5 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.2 1.6 GO:0006020 inositol metabolic process(GO:0006020)
0.2 0.4 GO:0032486 Rap protein signal transduction(GO:0032486)
0.2 1.6 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.2 1.5 GO:0023058 adaptation of signaling pathway(GO:0023058)
0.2 3.9 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.2 9.0 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.2 1.5 GO:0006828 manganese ion transport(GO:0006828)
0.2 2.4 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.2 1.0 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.2 2.7 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.2 0.9 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.2 7.0 GO:0006306 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.1 0.9 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 0.3 GO:0051026 chiasma assembly(GO:0051026)
0.1 2.5 GO:0010225 response to UV-C(GO:0010225)
0.1 0.7 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.1 1.7 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 2.5 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.1 5.3 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.1 0.6 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 0.4 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955)
0.1 3.6 GO:0051220 cytoplasmic sequestering of protein(GO:0051220)
0.1 1.2 GO:0006449 regulation of translational termination(GO:0006449)
0.1 1.2 GO:0098969 neurotransmitter receptor transport to plasma membrane(GO:0098877) neurotransmitter receptor transport to postsynaptic membrane(GO:0098969) establishment of protein localization to postsynaptic membrane(GO:1903540)
0.1 1.2 GO:0097352 autophagosome maturation(GO:0097352)
0.1 9.0 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.1 8.7 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.1 3.5 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.1 0.5 GO:0035094 response to nicotine(GO:0035094)
0.1 0.5 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 0.6 GO:0006817 phosphate ion transport(GO:0006817)
0.1 1.0 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.3 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.1 5.4 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 0.9 GO:0042402 cellular biogenic amine catabolic process(GO:0042402)
0.1 2.2 GO:0001893 maternal placenta development(GO:0001893)
0.1 2.9 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.1 1.5 GO:0006999 nuclear pore organization(GO:0006999)
0.1 0.3 GO:0010873 positive regulation of cholesterol esterification(GO:0010873)
0.1 0.3 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.1 0.9 GO:0016082 synaptic vesicle priming(GO:0016082)
0.1 0.2 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.1 2.9 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.1 3.2 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.1 0.2 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.1 0.7 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway(GO:2001243)
0.1 0.6 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1 0.8 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 1.4 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 0.4 GO:0060768 epithelial cell proliferation involved in prostate gland development(GO:0060767) regulation of epithelial cell proliferation involved in prostate gland development(GO:0060768) negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1 1.5 GO:0070527 platelet aggregation(GO:0070527)
0.1 0.2 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 6.0 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.1 0.4 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 0.5 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 0.3 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.1 0.7 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 0.8 GO:0016486 peptide hormone processing(GO:0016486)
0.1 1.2 GO:0030204 chondroitin sulfate metabolic process(GO:0030204)
0.1 0.7 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.1 0.2 GO:0051030 snRNA transport(GO:0051030)
0.1 0.3 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 2.2 GO:0050729 positive regulation of inflammatory response(GO:0050729)
0.1 3.1 GO:0006906 vesicle fusion(GO:0006906)
0.1 1.0 GO:0070207 protein homotrimerization(GO:0070207)
0.1 1.2 GO:0014911 positive regulation of smooth muscle cell migration(GO:0014911)
0.1 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.4 GO:0046548 retinal rod cell development(GO:0046548)
0.1 0.6 GO:1901798 positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.1 0.3 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.1 6.0 GO:0007266 Rho protein signal transduction(GO:0007266)
0.1 4.9 GO:0050821 protein stabilization(GO:0050821)
0.1 1.2 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 0.9 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.1 0.7 GO:0045332 phospholipid translocation(GO:0045332)
0.0 1.0 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.3 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.8 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 5.2 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 0.5 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0 0.5 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.3 GO:0051642 centrosome localization(GO:0051642)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 1.4 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.5 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 1.1 GO:0042177 negative regulation of protein catabolic process(GO:0042177)
0.0 0.9 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.1 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 1.3 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0010669 epithelial structure maintenance(GO:0010669)
0.0 0.2 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 2.1 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 1.7 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 0.0 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.0 0.1 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.2 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.1 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.1 GO:0046638 positive regulation of alpha-beta T cell differentiation(GO:0046638)
0.0 1.1 GO:0010506 regulation of autophagy(GO:0010506)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
10.6 31.9 GO:0043512 inhibin A complex(GO:0043512)
10.2 40.8 GO:0031673 H zone(GO:0031673)
8.1 24.3 GO:0072534 perineuronal net(GO:0072534)
7.8 39.2 GO:0032437 cuticular plate(GO:0032437)
6.5 58.7 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
6.2 55.9 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
5.8 109.5 GO:0071564 npBAF complex(GO:0071564)
4.7 93.0 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
4.1 61.4 GO:0043083 synaptic cleft(GO:0043083)
3.8 56.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
3.6 61.9 GO:0031045 dense core granule(GO:0031045)
3.5 52.9 GO:1902711 GABA-A receptor complex(GO:1902711)
3.1 39.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
3.0 15.2 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
3.0 126.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
3.0 59.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
2.9 11.6 GO:0097454 Schwann cell microvillus(GO:0097454)
2.6 54.9 GO:0031430 M band(GO:0031430)
2.3 25.6 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
2.2 8.7 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
2.0 10.2 GO:0070826 paraferritin complex(GO:0070826)
2.0 6.1 GO:0098835 presynaptic endosome(GO:0098830) presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
1.8 37.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
1.7 21.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
1.5 403.8 GO:0045211 postsynaptic membrane(GO:0045211)
1.3 5.1 GO:0014802 terminal cisterna(GO:0014802)
1.3 3.9 GO:0008091 spectrin(GO:0008091)
1.2 3.7 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
1.2 15.6 GO:0031672 A band(GO:0031672)
1.2 12.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
1.1 15.2 GO:0043196 varicosity(GO:0043196)
1.1 13.8 GO:0044300 cerebellar mossy fiber(GO:0044300)
1.0 9.0 GO:0071565 nBAF complex(GO:0071565)
1.0 42.0 GO:0044295 axonal growth cone(GO:0044295)
1.0 7.9 GO:0042581 specific granule(GO:0042581)
0.9 29.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.9 7.8 GO:0044294 dendritic growth cone(GO:0044294)
0.9 8.6 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.8 21.8 GO:0001917 photoreceptor inner segment(GO:0001917)
0.8 3.9 GO:0000235 astral microtubule(GO:0000235)
0.8 38.6 GO:0045171 intercellular bridge(GO:0045171)
0.8 17.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.8 5.3 GO:0033263 CORVET complex(GO:0033263)
0.7 76.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.7 2.9 GO:0031983 vesicle lumen(GO:0031983)
0.7 19.9 GO:0042734 presynaptic membrane(GO:0042734)
0.7 4.9 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.7 3.5 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.7 8.2 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.7 3.3 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.7 5.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.7 23.5 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.6 6.9 GO:0005677 chromatin silencing complex(GO:0005677)
0.6 8.7 GO:0043198 dendritic shaft(GO:0043198)
0.6 6.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.6 11.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.6 2.8 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.6 16.2 GO:0044291 cell-cell contact zone(GO:0044291)
0.6 113.6 GO:0060076 excitatory synapse(GO:0060076)
0.6 2.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.6 1.1 GO:0030478 actin cap(GO:0030478)
0.5 2.1 GO:0001651 dense fibrillar component(GO:0001651)
0.5 7.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.5 12.0 GO:0032809 neuronal cell body membrane(GO:0032809)
0.5 5.3 GO:0030057 desmosome(GO:0030057)
0.5 32.0 GO:0005913 cell-cell adherens junction(GO:0005913)
0.5 1.4 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.5 5.5 GO:0030673 axolemma(GO:0030673)
0.5 5.0 GO:0005915 zonula adherens(GO:0005915)
0.4 50.7 GO:0030017 sarcomere(GO:0030017)
0.4 22.0 GO:0008023 transcription elongation factor complex(GO:0008023)
0.4 32.7 GO:0042641 actomyosin(GO:0042641)
0.4 1.2 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.4 1.6 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.4 2.1 GO:0071437 invadopodium(GO:0071437)
0.4 1.4 GO:0005726 perichromatin fibrils(GO:0005726)
0.3 8.3 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.3 5.0 GO:0042588 zymogen granule(GO:0042588)
0.3 3.0 GO:0031258 lamellipodium membrane(GO:0031258)
0.3 18.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.3 31.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.3 2.9 GO:0000138 Golgi trans cisterna(GO:0000138)
0.3 1.6 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.3 2.2 GO:0070695 FHF complex(GO:0070695)
0.3 13.7 GO:0016328 lateral plasma membrane(GO:0016328)
0.3 6.5 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.3 5.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.3 11.9 GO:0009925 basal plasma membrane(GO:0009925)
0.3 11.2 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.3 2.4 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.3 203.6 GO:0005887 integral component of plasma membrane(GO:0005887)
0.3 2.3 GO:0001739 sex chromatin(GO:0001739)
0.3 25.1 GO:0030139 endocytic vesicle(GO:0030139)
0.3 22.9 GO:0031225 anchored component of membrane(GO:0031225)
0.3 0.9 GO:0044305 calyx of Held(GO:0044305)
0.3 2.9 GO:0070545 PeBoW complex(GO:0070545)
0.3 8.6 GO:0005905 clathrin-coated pit(GO:0005905)
0.3 1.4 GO:0045298 tubulin complex(GO:0045298)
0.3 17.7 GO:0055037 recycling endosome(GO:0055037)
0.3 10.0 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.3 1.8 GO:0097165 nuclear stress granule(GO:0097165)
0.3 1.8 GO:0090543 Flemming body(GO:0090543)
0.2 3.7 GO:0030127 COPII vesicle coat(GO:0030127)
0.2 1.0 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 4.2 GO:0005902 microvillus(GO:0005902)
0.2 6.0 GO:0035371 microtubule plus-end(GO:0035371)
0.2 1.3 GO:0030131 clathrin adaptor complex(GO:0030131)
0.2 8.6 GO:0031226 intrinsic component of plasma membrane(GO:0031226)
0.2 30.3 GO:0005802 trans-Golgi network(GO:0005802)
0.2 19.2 GO:0016605 PML body(GO:0016605)
0.2 2.8 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.2 2.6 GO:0097539 ciliary transition fiber(GO:0097539)
0.2 2.8 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.2 0.6 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.2 2.5 GO:0043005 neuron projection(GO:0043005)
0.2 0.6 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.2 0.2 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.2 1.7 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.2 2.9 GO:0060170 ciliary membrane(GO:0060170)
0.2 1.4 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.2 11.3 GO:0005923 bicellular tight junction(GO:0005923)
0.2 3.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.2 0.6 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.2 1.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 2.0 GO:0097458 neuron part(GO:0097458)
0.2 1.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.2 47.6 GO:0045202 synapse(GO:0045202)
0.2 7.4 GO:0072686 mitotic spindle(GO:0072686)
0.2 29.5 GO:0000139 Golgi membrane(GO:0000139)
0.1 0.6 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 0.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 1.6 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 19.9 GO:0030424 axon(GO:0030424)
0.1 4.3 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 0.4 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 2.0 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 3.3 GO:0008180 COP9 signalosome(GO:0008180)
0.1 5.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.3 GO:0031105 septin complex(GO:0031105)
0.1 1.2 GO:0045275 respiratory chain complex III(GO:0045275)
0.1 1.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 2.9 GO:0001726 ruffle(GO:0001726)
0.1 0.6 GO:0044615 nuclear pore central transport channel(GO:0044613) nuclear pore nuclear basket(GO:0044615)
0.1 0.6 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.1 38.1 GO:0005768 endosome(GO:0005768)
0.1 0.5 GO:0097361 CIA complex(GO:0097361)
0.1 1.8 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.1 1.2 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 0.3 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.1 1.7 GO:0005682 U5 snRNP(GO:0005682)
0.1 9.6 GO:0001650 fibrillar center(GO:0001650)
0.1 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 7.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 4.7 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 2.9 GO:0016592 mediator complex(GO:0016592)
0.1 3.3 GO:0072562 blood microparticle(GO:0072562)
0.1 4.6 GO:0005657 replication fork(GO:0005657)
0.1 7.9 GO:0043209 myelin sheath(GO:0043209)
0.1 1.6 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.1 59.4 GO:0005783 endoplasmic reticulum(GO:0005783)
0.1 1.6 GO:0032587 ruffle membrane(GO:0032587)
0.1 1.3 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 2.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 5.9 GO:0031965 nuclear membrane(GO:0031965)
0.0 80.9 GO:0016021 integral component of membrane(GO:0016021)
0.0 1.2 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.2 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 0.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.8 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.4 GO:0022627 small ribosomal subunit(GO:0015935) cytosolic small ribosomal subunit(GO:0022627)
0.0 0.1 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.7 GO:0005938 cell cortex(GO:0005938)
0.0 0.3 GO:0000795 synaptonemal complex(GO:0000795)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
12.5 49.9 GO:0030348 syntaxin-3 binding(GO:0030348)
10.5 62.9 GO:0070699 type II activin receptor binding(GO:0070699)
8.5 25.6 GO:0004517 nitric-oxide synthase activity(GO:0004517)
7.7 62.0 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
7.5 7.5 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
6.8 27.2 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
6.7 20.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
6.5 52.0 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529)
5.4 27.0 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
5.3 21.2 GO:0004952 dopamine neurotransmitter receptor activity(GO:0004952)
5.0 14.9 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
4.8 19.1 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
3.9 39.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
3.9 127.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
3.5 14.2 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
3.3 52.8 GO:0004385 guanylate kinase activity(GO:0004385)
3.3 13.2 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
3.0 47.9 GO:0035198 miRNA binding(GO:0035198)
3.0 29.9 GO:0042043 neurexin family protein binding(GO:0042043)
2.9 46.0 GO:0004890 GABA-A receptor activity(GO:0004890)
2.9 8.6 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
2.8 34.1 GO:0050897 cobalt ion binding(GO:0050897)
2.8 11.3 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
2.8 8.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
2.8 80.4 GO:1905030 voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
2.8 156.8 GO:0036002 pre-mRNA binding(GO:0036002)
2.7 32.5 GO:0097109 neuroligin family protein binding(GO:0097109)
2.7 80.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
2.6 18.4 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
2.5 12.5 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
2.4 9.7 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
2.3 11.6 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
2.3 11.5 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
2.3 6.8 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
2.3 9.0 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
2.2 48.1 GO:0030506 ankyrin binding(GO:0030506)
2.2 121.5 GO:0030507 spectrin binding(GO:0030507)
2.1 2.1 GO:0098821 BMP receptor activity(GO:0098821)
2.1 32.8 GO:0045499 chemorepellent activity(GO:0045499)
2.0 7.9 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
1.8 7.4 GO:0004111 creatine kinase activity(GO:0004111)
1.8 5.5 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
1.8 31.5 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
1.7 37.8 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
1.7 5.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
1.7 5.1 GO:0008502 melatonin receptor activity(GO:0008502)
1.7 5.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
1.6 4.9 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
1.6 20.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
1.6 7.8 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
1.5 4.5 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
1.5 6.0 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
1.5 5.9 GO:0099583 PLC activating G-protein coupled glutamate receptor activity(GO:0001639) A2A adenosine receptor binding(GO:0031687) G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
1.5 7.4 GO:0004359 glutaminase activity(GO:0004359)
1.5 5.9 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
1.5 46.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
1.4 15.7 GO:0019531 secondary active sulfate transmembrane transporter activity(GO:0008271) oxalate transmembrane transporter activity(GO:0019531)
1.4 5.5 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
1.4 9.5 GO:0032051 clathrin light chain binding(GO:0032051)
1.4 4.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
1.3 22.9 GO:0046625 sphingolipid binding(GO:0046625)
1.3 22.9 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
1.3 9.1 GO:0002162 dystroglycan binding(GO:0002162)
1.3 8.8 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
1.2 12.3 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
1.2 6.1 GO:0055100 adiponectin binding(GO:0055100)
1.2 7.3 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
1.2 6.0 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
1.2 3.6 GO:0005030 neurotrophin receptor activity(GO:0005030)
1.2 3.5 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
1.2 13.8 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
1.1 27.4 GO:0042287 MHC protein binding(GO:0042287)
1.1 52.6 GO:0046875 ephrin receptor binding(GO:0046875)
1.1 5.5 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
1.1 9.9 GO:0005523 tropomyosin binding(GO:0005523)
1.1 8.5 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
1.0 1.0 GO:1990715 mRNA CDS binding(GO:1990715)
1.0 5.2 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
1.0 4.9 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
1.0 8.7 GO:0038191 neuropilin binding(GO:0038191)
1.0 4.8 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
1.0 16.2 GO:0030275 LRR domain binding(GO:0030275)
1.0 16.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.9 3.8 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.9 5.5 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.9 4.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.9 8.0 GO:0070324 thyroid hormone binding(GO:0070324)
0.9 6.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.9 6.0 GO:0015301 anion:anion antiporter activity(GO:0015301)
0.8 2.5 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.8 17.5 GO:0042805 actinin binding(GO:0042805)
0.8 2.5 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.8 3.2 GO:0001847 opsonin receptor activity(GO:0001847)
0.8 5.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.8 2.4 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.8 7.6 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.8 1.5 GO:0001515 opioid peptide activity(GO:0001515)
0.7 13.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.7 7.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.7 5.1 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.7 1.4 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.7 54.2 GO:0005262 calcium channel activity(GO:0005262)
0.7 2.8 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.7 4.7 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.7 22.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.7 7.3 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.7 4.6 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.7 19.1 GO:0070412 R-SMAD binding(GO:0070412)
0.7 118.7 GO:0004386 helicase activity(GO:0004386)
0.7 2.6 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.6 1.9 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.6 70.9 GO:0005057 receptor signaling protein activity(GO:0005057)
0.6 1.2 GO:0019153 protein-disulfide reductase (glutathione) activity(GO:0019153)
0.6 12.6 GO:0031489 myosin V binding(GO:0031489)
0.6 66.0 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.6 6.8 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.6 2.2 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.5 8.6 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.5 1.6 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.5 3.6 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.5 2.6 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.5 4.5 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.5 125.1 GO:0008017 microtubule binding(GO:0008017)
0.5 1.9 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.5 2.3 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.5 3.7 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.5 17.8 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.4 3.1 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.4 2.2 GO:0004954 icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)
0.4 4.4 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.4 2.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.4 3.0 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.4 14.4 GO:0071889 14-3-3 protein binding(GO:0071889)
0.4 3.0 GO:0031419 cobalamin binding(GO:0031419)
0.4 3.3 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.4 11.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.4 2.8 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.4 41.0 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.4 3.2 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.4 6.0 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.4 12.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.4 1.6 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.4 27.4 GO:0030674 protein binding, bridging(GO:0030674)
0.4 2.7 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.4 10.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.4 2.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.4 14.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.4 1.4 GO:0050733 RS domain binding(GO:0050733)
0.4 8.5 GO:0070064 proline-rich region binding(GO:0070064)
0.4 5.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.3 2.8 GO:0008417 fucosyltransferase activity(GO:0008417)
0.3 18.7 GO:0048365 Rac GTPase binding(GO:0048365)
0.3 1.3 GO:0019770 IgG receptor activity(GO:0019770)
0.3 10.1 GO:0030276 clathrin binding(GO:0030276)
0.3 0.9 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.3 1.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.3 1.5 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.3 4.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.3 2.4 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.3 0.9 GO:0001565 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
0.3 6.4 GO:0004407 histone deacetylase activity(GO:0004407)
0.3 4.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.3 5.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.3 3.6 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.3 2.2 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.3 4.1 GO:0042056 chemoattractant activity(GO:0042056)
0.3 1.9 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.3 1.4 GO:0097643 amylin receptor activity(GO:0097643)
0.3 2.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.3 6.7 GO:0097602 cullin family protein binding(GO:0097602)
0.3 2.0 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.3 1.5 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.3 6.0 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.2 19.5 GO:0017137 Rab GTPase binding(GO:0017137)
0.2 63.2 GO:0005096 GTPase activator activity(GO:0005096)
0.2 3.9 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.2 4.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.2 1.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.2 1.5 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.2 2.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 4.9 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.2 0.7 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.2 2.5 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.2 7.7 GO:0019894 kinesin binding(GO:0019894)
0.2 2.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.2 4.3 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.2 2.2 GO:0001972 retinoic acid binding(GO:0001972)
0.2 1.3 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.2 2.4 GO:0043422 protein kinase B binding(GO:0043422)
0.2 4.9 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.2 5.1 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 7.3 GO:0032452 histone demethylase activity(GO:0032452)
0.2 3.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 35.7 GO:0003714 transcription corepressor activity(GO:0003714)
0.2 3.2 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.2 12.6 GO:0005516 calmodulin binding(GO:0005516)
0.2 6.8 GO:0015459 potassium channel regulator activity(GO:0015459)
0.2 0.9 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.2 1.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.2 1.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.2 0.9 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.2 2.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.2 5.0 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.2 5.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.2 1.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.2 1.0 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.2 1.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.2 3.7 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.2 55.0 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.2 11.5 GO:0015631 tubulin binding(GO:0015631)
0.2 0.8 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.2 1.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.2 1.2 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.9 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 3.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 1.7 GO:0050681 androgen receptor binding(GO:0050681)
0.1 3.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 5.3 GO:0015485 cholesterol binding(GO:0015485)
0.1 0.9 GO:0097110 scaffold protein binding(GO:0097110)
0.1 2.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 1.2 GO:0031543 peptidyl-proline dioxygenase activity(GO:0031543)
0.1 0.6 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 9.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.0 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 1.9 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 3.1 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 24.0 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.1 1.8 GO:0003924 GTPase activity(GO:0003924)
0.1 36.3 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.1 2.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 1.5 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 1.6 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 1.1 GO:0005537 mannose binding(GO:0005537)
0.1 1.1 GO:0046965 retinoid X receptor binding(GO:0046965)
0.1 1.6 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1 11.1 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.1 1.3 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769)
0.1 0.7 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.1 4.1 GO:0008374 O-acyltransferase activity(GO:0008374)
0.1 4.1 GO:0019903 protein phosphatase binding(GO:0019903)
0.1 1.2 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 0.8 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.7 GO:0005521 lamin binding(GO:0005521)
0.1 0.4 GO:0031690 adrenergic receptor binding(GO:0031690)
0.1 5.5 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 0.3 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1 0.4 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.1 1.7 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 2.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 2.7 GO:0002039 p53 binding(GO:0002039)
0.1 0.6 GO:0031386 protein tag(GO:0031386)
0.1 1.5 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 1.3 GO:0050699 WW domain binding(GO:0050699)
0.0 0.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 1.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 2.7 GO:0000149 SNARE binding(GO:0000149)
0.0 0.3 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 1.1 GO:0017022 myosin binding(GO:0017022)
0.0 0.6 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.1 GO:0008252 nucleotidase activity(GO:0008252)
0.0 0.5 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.7 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 1.3 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 0.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.0 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.1 GO:0005522 profilin binding(GO:0005522)
0.0 0.3 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.3 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.6 GO:0003697 single-stranded DNA binding(GO:0003697)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 74.3 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
1.5 56.3 PID_IL3_PATHWAY IL3-mediated signaling events
1.3 107.6 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
1.2 55.9 PID_REELIN_PATHWAY Reelin signaling pathway
1.2 12.7 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
1.0 38.8 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
1.0 30.2 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.9 14.6 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.9 41.8 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.9 54.0 PID_LKB1_PATHWAY LKB1 signaling events
0.8 40.7 PID_FGF_PATHWAY FGF signaling pathway
0.8 27.1 PID_ALK1_PATHWAY ALK1 signaling events
0.7 8.6 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.7 36.7 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.7 30.7 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.7 37.1 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.7 16.0 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.7 27.0 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.7 12.5 PID_EPHA_FWDPATHWAY EPHA forward signaling
0.6 13.0 ST_GA12_PATHWAY G alpha 12 Pathway
0.6 21.5 PID_TNF_PATHWAY TNF receptor signaling pathway
0.6 24.4 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.4 14.2 PID_IL4_2PATHWAY IL4-mediated signaling events
0.4 6.9 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.4 3.2 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.4 17.1 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.4 4.4 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.3 11.3 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.3 4.4 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.3 38.1 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.3 27.6 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.3 2.1 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.3 14.6 PID_ERBB1_DOWNSTREAM_PATHWAY ErbB1 downstream signaling
0.3 4.9 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.2 4.1 ST_G_ALPHA_I_PATHWAY G alpha i Pathway
0.2 2.0 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.2 6.1 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.2 10.1 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.2 1.5 PID_IL2_PI3K_PATHWAY IL2 signaling events mediated by PI3K
0.2 4.5 PID_CD8_TCR_PATHWAY TCR signaling in naïve CD8+ T cells
0.1 6.5 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.1 0.7 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.1 1.5 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events
0.1 1.9 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 1.5 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 2.2 PID_ARF6_PATHWAY Arf6 signaling events
0.1 1.4 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 0.9 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 1.8 PID_CXCR4_PATHWAY CXCR4-mediated signaling events
0.1 1.1 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.1 3.5 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.1 1.0 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.1 1.2 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 0.3 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.0 1.7 PID_RB_1PATHWAY Regulation of retinoblastoma protein
0.0 0.7 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.0 0.5 PID_HIF2PATHWAY HIF-2-alpha transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
8.0 31.9 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
5.3 52.6 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
4.3 154.8 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
3.5 66.9 REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT Genes involved in Ligand-gated ion channel transport
3.3 142.6 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
2.9 79.0 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
2.7 34.6 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
2.4 65.8 REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
1.9 68.0 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
1.6 56.6 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
1.5 48.3 REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
1.5 17.5 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
1.5 33.4 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
1.2 11.0 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
1.2 19.8 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
1.1 88.2 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions
1.0 7.0 REACTOME_SIGNALING_BY_ACTIVATED_POINT_MUTANTS_OF_FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.9 23.1 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.9 7.3 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.9 4.3 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.8 2.5 REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.7 2.2 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.7 7.9 REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.7 6.0 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.7 12.5 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.6 5.5 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.6 5.5 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.6 23.2 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.6 4.6 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.6 8.3 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.6 2.8 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.5 21.0 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.5 20.9 REACTOME_RNA_POL_III_TRANSCRIPTION Genes involved in RNA Polymerase III Transcription
0.5 0.9 REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.5 7.4 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.5 34.6 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.5 2.7 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.4 3.9 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.4 4.9 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.4 14.1 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.4 10.3 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.4 1.8 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.4 2.2 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.3 5.9 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.3 5.5 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.3 12.2 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.3 6.8 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.3 2.9 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.3 3.8 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.3 2.8 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.3 9.2 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.3 6.4 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.3 5.6 REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.3 1.3 REACTOME_ADP_SIGNALLING_THROUGH_P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.2 2.6 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.2 4.8 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.2 2.9 REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS Genes involved in Glucagon-type ligand receptors
0.2 5.7 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.2 5.0 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 3.2 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.2 11.0 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.2 3.0 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.2 1.0 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2 2.1 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 2.6 REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 2.2 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.1 1.1 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 7.8 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 1.8 REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS Genes involved in Prolonged ERK activation events
0.1 10.6 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.1 3.7 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 5.7 REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 0.4 REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.1 2.4 REACTOME_RNA_POL_I_TRANSCRIPTION_INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.1 1.8 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling
0.1 1.9 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 0.9 REACTOME_ACTIVATION_OF_CHAPERONES_BY_ATF6_ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.1 1.7 REACTOME_REGULATORY_RNA_PATHWAYS Genes involved in Regulatory RNA pathways
0.1 1.3 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 2.1 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.5 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.4 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 0.7 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.0 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.7 REACTOME_SIGNALING_BY_EGFR_IN_CANCER Genes involved in Signaling by EGFR in Cancer
0.0 0.6 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.2 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 1.6 REACTOME_TRIGLYCERIDE_BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 0.5 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.3 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.0 1.0 REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.2 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 2.1 REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.0 0.6 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.4 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.3 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.3 REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.3 REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.4 REACTOME_MRNA_SPLICING_MINOR_PATHWAY Genes involved in mRNA Splicing - Minor Pathway