Motif ID: Hoxc13_Hoxd13

Z-value: 0.907







Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxc13_Hoxd13

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_8518801 12.259 ENSMUST00000061601.7
Ust
uronyl-2-sulfotransferase
chr17_+_75178911 8.276 ENSMUST00000112514.1
Ltbp1
latent transforming growth factor beta binding protein 1
chr4_+_54945038 7.745 ENSMUST00000133895.1
Zfp462
zinc finger protein 462
chr17_+_75178797 7.270 ENSMUST00000112516.1
ENSMUST00000135447.1
Ltbp1

latent transforming growth factor beta binding protein 1

chr6_+_108213086 7.197 ENSMUST00000032192.6
Itpr1
inositol 1,4,5-trisphosphate receptor 1
chr1_-_56978534 6.254 ENSMUST00000177282.1
Satb2
special AT-rich sequence binding protein 2
chr17_-_6477102 5.439 ENSMUST00000167717.2
Tmem181b-ps
transmembrane protein 181B, pseudogene
chr16_-_74411776 5.132 ENSMUST00000116586.2
Robo2
roundabout homolog 2 (Drosophila)
chr17_+_6270475 4.832 ENSMUST00000088940.4
Tmem181a
transmembrane protein 181A
chr18_+_69346143 4.063 ENSMUST00000114980.1
Tcf4
transcription factor 4
chr7_-_73537621 4.051 ENSMUST00000172704.1
Chd2
chromodomain helicase DNA binding protein 2
chr5_+_17574268 3.488 ENSMUST00000030568.7
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr16_+_23226014 3.478 ENSMUST00000178797.1
St6gal1
beta galactoside alpha 2,6 sialyltransferase 1
chr12_-_34528844 2.940 ENSMUST00000110819.2
Hdac9
histone deacetylase 9
chr7_+_67647405 2.750 ENSMUST00000032774.8
ENSMUST00000107471.1
Ttc23

tetratricopeptide repeat domain 23

chr1_-_74124420 2.731 ENSMUST00000169786.1
Tns1
tensin 1
chr14_-_118052235 2.450 ENSMUST00000022725.2
Dct
dopachrome tautomerase
chr3_+_59006978 2.035 ENSMUST00000040325.7
ENSMUST00000164225.1
ENSMUST00000040846.8
ENSMUST00000029393.8
Med12l



mediator of RNA polymerase II transcription, subunit 12 homolog (yeast)-like



chr4_-_82850721 1.986 ENSMUST00000139401.1
Zdhhc21
zinc finger, DHHC domain containing 21
chr4_-_110290884 1.928 ENSMUST00000142722.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr17_-_51826562 1.909 ENSMUST00000024720.4
ENSMUST00000129667.1
ENSMUST00000156051.1
ENSMUST00000169480.1
ENSMUST00000148559.1
Satb1




special AT-rich sequence binding protein 1




chr11_+_77216180 1.884 ENSMUST00000037912.5
ENSMUST00000156488.1
Ssh2

slingshot homolog 2 (Drosophila)

chr9_-_96719404 1.748 ENSMUST00000140121.1
Zbtb38
zinc finger and BTB domain containing 38
chr9_-_96719549 1.733 ENSMUST00000128269.1
Zbtb38
zinc finger and BTB domain containing 38
chrX_-_7319291 1.725 ENSMUST00000128319.1
Clcn5
chloride channel 5
chr8_-_70139197 1.593 ENSMUST00000075724.7
Rfxank
regulatory factor X-associated ankyrin-containing protein
chrX_-_7319186 1.530 ENSMUST00000115746.1
Clcn5
chloride channel 5
chr1_+_72307413 1.516 ENSMUST00000027379.8
Xrcc5
X-ray repair complementing defective repair in Chinese hamster cells 5
chr17_-_57000018 1.481 ENSMUST00000002740.2
Pspn
persephin
chr13_+_16014457 1.295 ENSMUST00000164993.1
Inhba
inhibin beta-A
chr6_-_112947246 1.240 ENSMUST00000088373.4
Srgap3
SLIT-ROBO Rho GTPase activating protein 3
chr5_-_62766153 1.202 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr19_-_7341848 1.188 ENSMUST00000171393.1
Mark2
MAP/microtubule affinity-regulating kinase 2
chr9_-_64022043 1.160 ENSMUST00000041029.5
Smad6
SMAD family member 6
chr1_-_45503282 1.119 ENSMUST00000086430.4
Col5a2
collagen, type V, alpha 2
chr2_+_112265809 1.101 ENSMUST00000110991.2
Slc12a6
solute carrier family 12, member 6
chr6_+_71909046 1.062 ENSMUST00000055296.8
Polr1a
polymerase (RNA) I polypeptide A
chr2_-_66440753 0.968 ENSMUST00000112371.2
ENSMUST00000138910.1
Scn1a

sodium channel, voltage-gated, type I, alpha

chr17_+_43568641 0.961 ENSMUST00000169694.1
Pla2g7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr14_+_124005355 0.926 ENSMUST00000166105.1
Gm17615
predicted gene, 17615
chr17_+_43568475 0.910 ENSMUST00000167418.1
Pla2g7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr2_+_35132194 0.886 ENSMUST00000113034.1
ENSMUST00000113037.3
ENSMUST00000113033.2
Cep110


centrosomal protein 110


chr17_+_43568269 0.876 ENSMUST00000024706.5
Pla2g7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr1_-_36273425 0.765 ENSMUST00000056946.6
Neurl3
neuralized homolog 3 homolog (Drosophila)
chr8_+_83666827 0.744 ENSMUST00000019608.5
Ptger1
prostaglandin E receptor 1 (subtype EP1)
chr10_-_120979327 0.681 ENSMUST00000119944.1
ENSMUST00000119093.1
Lemd3

LEM domain containing 3

chr18_-_46280820 0.664 ENSMUST00000025354.3
Pggt1b
protein geranylgeranyltransferase type I, beta subunit
chr1_-_163289214 0.647 ENSMUST00000183691.1
Prrx1
paired related homeobox 1
chr5_-_121836810 0.646 ENSMUST00000118580.1
ENSMUST00000040308.7
Sh2b3

SH2B adaptor protein 3

chr3_+_126597415 0.621 ENSMUST00000066452.7
ENSMUST00000171289.1
ENSMUST00000106399.1
Camk2d


calcium/calmodulin-dependent protein kinase II, delta


chr3_+_79885930 0.568 ENSMUST00000029567.8
Fam198b
family with sequence similarity 198, member B
chr2_-_170427828 0.561 ENSMUST00000013667.2
ENSMUST00000109152.2
ENSMUST00000068137.4
Bcas1


breast carcinoma amplified sequence 1


chr11_-_5381734 0.489 ENSMUST00000172492.1
Znrf3
zinc and ring finger 3
chr11_-_23895208 0.484 ENSMUST00000102863.2
ENSMUST00000020513.3
Papolg

poly(A) polymerase gamma

chr10_-_128696257 0.480 ENSMUST00000000727.2
Rab5b
RAB5B, member RAS oncogene family
chr7_-_119895446 0.479 ENSMUST00000098080.2
Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr13_-_21402688 0.441 ENSMUST00000117721.1
ENSMUST00000070785.8
ENSMUST00000116433.1
ENSMUST00000116434.3
Zkscan3



zinc finger with KRAB and SCAN domains 3



chr18_+_37355271 0.412 ENSMUST00000051163.1
Pcdhb8
protocadherin beta 8
chr16_-_57231434 0.410 ENSMUST00000023431.6
Tbc1d23
TBC1 domain family, member 23
chr14_+_32321987 0.398 ENSMUST00000022480.7
Ogdhl
oxoglutarate dehydrogenase-like
chr5_-_62765618 0.389 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr14_+_77156733 0.368 ENSMUST00000022589.7
Enox1
ecto-NOX disulfide-thiol exchanger 1
chr15_+_99074968 0.362 ENSMUST00000039665.6
Troap
trophinin associated protein
chr14_-_76110760 0.355 ENSMUST00000022585.3
Gpalpp1
GPALPP motifs containing 1
chr2_-_180824596 0.354 ENSMUST00000148700.1
Gm14340
predicted gene 14340
chr11_-_5542177 0.322 ENSMUST00000020776.4
Ccdc117
coiled-coil domain containing 117
chr9_+_50575273 0.318 ENSMUST00000059081.6
ENSMUST00000180021.1
Il18

interleukin 18

chr12_-_48559971 0.317 ENSMUST00000169406.1
Gm1818
predicted gene 1818
chr6_+_134929089 0.311 ENSMUST00000183867.1
ENSMUST00000184991.1
ENSMUST00000183905.1
RP23-45G16.5


RP23-45G16.5


chr1_+_59256906 0.299 ENSMUST00000160662.1
ENSMUST00000114248.2
Cdk15

cyclin-dependent kinase 15

chr3_-_142169196 0.299 ENSMUST00000098568.1
Bmpr1b
bone morphogenetic protein receptor, type 1B
chr5_-_66514815 0.258 ENSMUST00000161879.1
ENSMUST00000159357.1
Apbb2

amyloid beta (A4) precursor protein-binding, family B, member 2

chr9_+_92542223 0.257 ENSMUST00000070522.7
ENSMUST00000160359.1
Plod2

procollagen lysine, 2-oxoglutarate 5-dioxygenase 2

chr5_+_92809372 0.247 ENSMUST00000113054.2
Shroom3
shroom family member 3
chr14_-_103346765 0.228 ENSMUST00000159855.1
Mycbp2
MYC binding protein 2
chr11_-_102407315 0.226 ENSMUST00000149777.1
ENSMUST00000154001.1
Slc25a39

solute carrier family 25, member 39

chr9_-_50659780 0.190 ENSMUST00000034567.3
Dlat
dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)
chr1_+_53313636 0.190 ENSMUST00000114484.1
Osgepl1
O-sialoglycoprotein endopeptidase-like 1
chr3_-_142169311 0.174 ENSMUST00000106230.1
Bmpr1b
bone morphogenetic protein receptor, type 1B
chr3_+_102735202 0.156 ENSMUST00000119902.1
Tspan2
tetraspanin 2
chr4_+_21879662 0.141 ENSMUST00000029909.2
Coq3
coenzyme Q3 homolog, methyltransferase (yeast)
chr3_+_95658771 0.112 ENSMUST00000178686.1
Mcl1
myeloid cell leukemia sequence 1
chr17_+_46650328 0.103 ENSMUST00000043464.7
Cul7
cullin 7
chr7_-_30612731 0.095 ENSMUST00000006476.4
Upk1a
uroplakin 1A
chr1_-_74600564 0.069 ENSMUST00000127938.1
ENSMUST00000154874.1
Rnf25

ring finger protein 25

chr9_+_32696005 0.068 ENSMUST00000034534.6
ENSMUST00000050797.7
ENSMUST00000184887.1
Ets1


E26 avian leukemia oncogene 1, 5' domain


chr8_+_13339656 0.066 ENSMUST00000170909.1
Tfdp1
transcription factor Dp 1
chr11_-_102407899 0.060 ENSMUST00000124755.1
Slc25a39
solute carrier family 25, member 39
chr8_+_56551090 0.060 ENSMUST00000040218.5
ENSMUST00000110322.3
Fbxo8

F-box protein 8

chr19_-_41896132 0.045 ENSMUST00000038677.3
Rrp12
ribosomal RNA processing 12 homolog (S. cerevisiae)
chr4_-_148500449 0.034 ENSMUST00000030840.3
Angptl7
angiopoietin-like 7

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.1 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
1.2 7.2 GO:0042045 epithelial fluid transport(GO:0042045)
0.9 3.5 GO:2000110 protein sialylation(GO:1990743) negative regulation of macrophage apoptotic process(GO:2000110)
0.8 4.8 GO:0009405 pathogenesis(GO:0009405)
0.6 15.9 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.6 3.5 GO:0003350 pulmonary myocardium development(GO:0003350)
0.5 2.7 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
0.4 2.4 GO:0006570 tyrosine metabolic process(GO:0006570)
0.4 6.3 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.4 1.5 GO:0071475 cellular hyperosmotic salinity response(GO:0071475) negative regulation of t-circle formation(GO:1904430)
0.4 1.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.4 4.1 GO:0042118 endothelial cell activation(GO:0042118)
0.3 1.3 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.3 2.9 GO:0034983 peptidyl-lysine deacetylation(GO:0034983) regulation of skeletal muscle fiber development(GO:0048742)
0.3 1.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.2 0.7 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.2 1.1 GO:0071472 cellular response to salt stress(GO:0071472)
0.2 4.1 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.2 2.0 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.2 1.1 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.1 0.7 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 7.7 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.1 1.9 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.5 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 0.6 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.1 0.5 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 1.0 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 3.3 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 0.5 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.1 12.1 GO:0030010 establishment of cell polarity(GO:0030010)
0.1 0.6 GO:0048664 neuron fate determination(GO:0048664)
0.1 0.3 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 1.9 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.4 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 2.7 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.3 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.2 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0 0.1 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.5 GO:0010225 response to UV-C(GO:0010225)
0.0 1.5 GO:0001658 branching involved in ureteric bud morphogenesis(GO:0001658)
0.0 0.2 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.0 1.9 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.6 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.6 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 3.5 GO:0006275 regulation of DNA replication(GO:0006275)
0.0 0.1 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 0.1 GO:0030578 PML body organization(GO:0030578) positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.0 0.5 GO:0006378 mRNA polyadenylation(GO:0006378)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 15.5 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
2.4 7.2 GO:0031088 platelet dense granule membrane(GO:0031088)
0.4 1.3 GO:0043512 inhibin A complex(GO:0043512)
0.4 1.5 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.4 1.1 GO:0005588 collagen type V trimer(GO:0005588)
0.3 3.5 GO:0000138 Golgi trans cisterna(GO:0000138)
0.2 2.7 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 5.1 GO:0030673 axolemma(GO:0030673)
0.1 1.9 GO:0042788 polysomal ribosome(GO:0042788)
0.1 2.4 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 9.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 1.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 1.0 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 2.0 GO:0016592 mediator complex(GO:0016592)
0.0 0.4 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.7 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.4 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 1.6 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.9 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.6 GO:0043194 axon initial segment(GO:0043194)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 3.3 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 2.0 GO:0032993 protein-DNA complex(GO:0032993)
0.0 14.8 GO:0005794 Golgi apparatus(GO:0005794)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 15.5 GO:0050436 microfibril binding(GO:0050436)
2.4 7.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
1.0 4.1 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.7 3.5 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.6 5.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.4 4.8 GO:0015643 toxic substance binding(GO:0015643)
0.4 2.5 GO:0070697 activin receptor binding(GO:0070697)
0.3 2.7 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.3 3.5 GO:0038191 neuropilin binding(GO:0038191)
0.2 12.3 GO:0008146 sulfotransferase activity(GO:0008146)
0.2 3.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.2 2.4 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.2 1.1 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.2 1.5 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 0.7 GO:0004954 icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)
0.1 3.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.7 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.1 2.9 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.3 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 0.6 GO:0031432 titin binding(GO:0031432)
0.1 1.1 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 0.5 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 2.0 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.3 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1 0.2 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.1 0.4 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 1.0 GO:0031402 sodium ion binding(GO:0031402)
0.1 0.5 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 1.9 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.2 GO:0016417 S-acyltransferase activity(GO:0016417)
0.0 2.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.1 GO:0008169 C-methyltransferase activity(GO:0008169)
0.0 1.6 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 1.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 4.1 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 0.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.5 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.3 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 1.2 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.5 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 8.9 GO:0003682 chromatin binding(GO:0003682)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 7.8 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 15.5 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 2.7 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 1.5 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 2.8 PID_HDAC_CLASSII_PATHWAY Signaling events mediated by HDAC Class II
0.0 4.0 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 2.7 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 1.6 PID_BMP_PATHWAY BMP receptor signaling
0.0 1.3 PID_ALK1_PATHWAY ALK1 signaling events
0.0 1.9 PID_CASPASE_PATHWAY Caspase cascade in apoptosis
0.0 1.1 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.3 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.0 0.6 PID_EPO_PATHWAY EPO signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.5 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.3 1.3 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.2 0.7 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.2 12.3 REACTOME_CHONDROITIN_SULFATE_DERMATAN_SULFATE_METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.2 2.7 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.2 6.4 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.1 4.1 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 1.5 REACTOME_INTEGRATION_OF_PROVIRUS Genes involved in Integration of provirus
0.1 2.0 REACTOME_ENOS_ACTIVATION_AND_REGULATION Genes involved in eNOS activation and regulation
0.1 2.6 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.6 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 1.1 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 2.9 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.9 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.6 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.6 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.2 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.1 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides