Motif ID: Hoxc6

Z-value: 0.297


Transcription factors associated with Hoxc6:

Gene SymbolEntrez IDGene Name
Hoxc6 ENSMUSG00000001661.4 Hoxc6



Activity profile for motif Hoxc6.

activity profile for motif Hoxc6


Sorted Z-values histogram for motif Hoxc6

Sorted Z-values for motif Hoxc6



Network of associatons between targets according to the STRING database.



Top targets:


Showing 1 to 20 of 53 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_17574268 2.049 ENSMUST00000030568.7
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr4_+_144893127 1.339 ENSMUST00000142808.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr7_+_73740277 1.069 ENSMUST00000107456.2
Fam174b
family with sequence similarity 174, member B
chr1_-_22315792 0.961 ENSMUST00000164877.1
Rims1
regulating synaptic membrane exocytosis 1
chr3_+_151437887 0.868 ENSMUST00000046977.7
Eltd1
EGF, latrophilin seven transmembrane domain containing 1
chr3_+_5218546 0.858 ENSMUST00000026284.6
Zfhx4
zinc finger homeodomain 4
chr19_+_26748268 0.783 ENSMUST00000175791.1
ENSMUST00000176698.1
ENSMUST00000177252.1
ENSMUST00000176475.1
ENSMUST00000112637.2
Smarca2




SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2




chr3_+_5218516 0.735 ENSMUST00000175866.1
Zfhx4
zinc finger homeodomain 4
chr3_+_66985680 0.634 ENSMUST00000065047.6
Rsrc1
arginine/serine-rich coiled-coil 1
chr3_-_113574242 0.632 ENSMUST00000142505.2
Amy1
amylase 1, salivary
chr10_-_100589205 0.562 ENSMUST00000054471.8
4930430F08Rik
RIKEN cDNA 4930430F08 gene
chr3_+_5218589 0.533 ENSMUST00000177488.1
Zfhx4
zinc finger homeodomain 4
chr8_-_54724317 0.510 ENSMUST00000129132.2
ENSMUST00000150488.1
ENSMUST00000127511.2
Wdr17


WD repeat domain 17


chr19_+_11469353 0.493 ENSMUST00000165310.1
Ms4a6c
membrane-spanning 4-domains, subfamily A, member 6C
chrX_-_143933204 0.491 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chrX_-_143933089 0.444 ENSMUST00000087313.3
Dcx
doublecortin
chr18_+_37484955 0.444 ENSMUST00000053856.4
Pcdhb17
protocadherin beta 17
chr2_+_65620829 0.442 ENSMUST00000028377.7
Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr11_-_26210553 0.433 ENSMUST00000101447.3
5730522E02Rik
RIKEN cDNA 5730522E02 gene
chr10_-_70655934 0.379 ENSMUST00000162144.1
ENSMUST00000162793.1
Phyhipl

phytanoyl-CoA hydroxylase interacting protein-like


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 1.9 GO:0003350 pulmonary myocardium development(GO:0003350)
0.1 1.3 GO:0042572 retinol metabolic process(GO:0042572)
0.0 1.1 GO:0046677 response to antibiotic(GO:0046677)
0.2 1.0 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.1 0.9 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.8 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 0.3 GO:0034035 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.1 0.3 GO:0033762 response to glucagon(GO:0033762)
0.1 0.3 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.3 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.3 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 0.2 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) regulation of connective tissue replacement(GO:1905203)
0.0 0.2 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.1 GO:0052695 cellular glucuronidation(GO:0052695)

Gene overrepresentation in cellular_component category:

Showing 1 to 6 of 6 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.0 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.0 0.8 GO:0071564 npBAF complex(GO:0071564)
0.0 0.3 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.3 GO:0045275 respiratory chain complex III(GO:0045275)
0.0 0.3 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)

Gene overrepresentation in molecular_function category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.0 GO:0038191 neuropilin binding(GO:0038191)
0.2 1.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.2 0.6 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.0 0.5 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 0.3 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.1 0.3 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.3 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.3 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)

Gene overrepresentation in C2:CP category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.0 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.3 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.9 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.0 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.3 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.3 REACTOME_REGULATORY_RNA_PATHWAYS Genes involved in Regulatory RNA pathways