Motif ID: Hsf2

Z-value: 1.672


Transcription factors associated with Hsf2:

Gene SymbolEntrez IDGene Name
Hsf2 ENSMUSG00000019878.7 Hsf2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hsf2mm10_v2_chr10_+_57486354_574864140.321.9e-02Click!


Activity profile for motif Hsf2.

activity profile for motif Hsf2


Sorted Z-values histogram for motif Hsf2

Sorted Z-values for motif Hsf2



Network of associatons between targets according to the STRING database.



First level regulatory network of Hsf2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_25797032 15.357 ENSMUST00000165838.1
ENSMUST00000002344.6
Metrn

meteorin, glial cell differentiation regulator

chr4_+_154960915 14.756 ENSMUST00000049621.6
Hes5
hairy and enhancer of split 5 (Drosophila)
chr10_-_92164666 14.059 ENSMUST00000183123.1
ENSMUST00000182033.1
Rmst

rhabdomyosarcoma 2 associated transcript (non-coding RNA)

chr17_-_70849644 13.572 ENSMUST00000134654.1
ENSMUST00000172229.1
ENSMUST00000127719.1
Tgif1


TGFB-induced factor homeobox 1


chr17_-_70851189 13.539 ENSMUST00000059775.8
Tgif1
TGFB-induced factor homeobox 1
chr11_-_11970540 12.800 ENSMUST00000109653.1
Grb10
growth factor receptor bound protein 10
chr13_+_51645232 12.525 ENSMUST00000075853.5
Cks2
CDC28 protein kinase regulatory subunit 2
chr10_-_78591945 12.307 ENSMUST00000040580.6
Syde1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr10_+_4710119 11.504 ENSMUST00000105588.1
ENSMUST00000105589.1
Esr1

estrogen receptor 1 (alpha)

chr10_+_84838143 11.333 ENSMUST00000095388.4
Rfx4
regulatory factor X, 4 (influences HLA class II expression)
chr5_-_5514730 10.784 ENSMUST00000115445.1
ENSMUST00000179804.1
ENSMUST00000125110.1
ENSMUST00000115446.1
Cldn12



claudin 12



chr7_-_4752972 10.753 ENSMUST00000183971.1
ENSMUST00000182173.1
ENSMUST00000182738.1
ENSMUST00000184143.1
ENSMUST00000182111.1
ENSMUST00000182048.1
ENSMUST00000063324.7
Cox6b2






cytochrome c oxidase subunit VIb polypeptide 2






chr18_-_80986578 10.221 ENSMUST00000057950.7
Sall3
sal-like 3 (Drosophila)
chr1_+_136467958 10.151 ENSMUST00000047817.6
Kif14
kinesin family member 14
chr1_-_133424377 9.654 ENSMUST00000153799.1
Sox13
SRY-box containing gene 13
chr5_-_5514873 9.584 ENSMUST00000060947.7
Cldn12
claudin 12
chr12_-_91746020 9.466 ENSMUST00000166967.1
Ston2
stonin 2
chr9_+_44134562 9.413 ENSMUST00000034650.8
ENSMUST00000098852.2
Mcam

melanoma cell adhesion molecule

chr2_+_25180737 9.250 ENSMUST00000104999.2
Nrarp
Notch-regulated ankyrin repeat protein
chr1_-_72874877 9.115 ENSMUST00000027377.8
Igfbp5
insulin-like growth factor binding protein 5
chr2_+_52038005 9.108 ENSMUST00000065927.5
Tnfaip6
tumor necrosis factor alpha induced protein 6
chr9_+_7764041 8.894 ENSMUST00000052865.9
Tmem123
transmembrane protein 123
chr11_-_89302545 8.650 ENSMUST00000061728.3
Nog
noggin
chr2_+_152847961 8.590 ENSMUST00000164120.1
ENSMUST00000178997.1
ENSMUST00000109816.1
Tpx2


TPX2, microtubule-associated protein homolog (Xenopus laevis)


chr5_+_92683625 8.564 ENSMUST00000168878.1
Shroom3
shroom family member 3
chr18_+_50053282 8.302 ENSMUST00000148159.2
Tnfaip8
tumor necrosis factor, alpha-induced protein 8
chr14_-_48667508 8.292 ENSMUST00000144465.1
ENSMUST00000133479.1
ENSMUST00000119070.1
ENSMUST00000152018.1
Otx2



orthodenticle homolog 2 (Drosophila)



chr2_-_26503814 8.249 ENSMUST00000028288.4
Notch1
notch 1
chr14_-_65833963 8.120 ENSMUST00000022613.9
Esco2
establishment of cohesion 1 homolog 2 (S. cerevisiae)
chr2_+_152847993 8.114 ENSMUST00000028969.8
Tpx2
TPX2, microtubule-associated protein homolog (Xenopus laevis)
chr3_+_94342092 7.933 ENSMUST00000029794.5
Them5
thioesterase superfamily member 5
chr15_+_25773985 7.864 ENSMUST00000125667.1
Myo10
myosin X
chr6_-_95718800 7.757 ENSMUST00000079847.5
Suclg2
succinate-Coenzyme A ligase, GDP-forming, beta subunit
chr9_-_114781986 7.727 ENSMUST00000035009.8
ENSMUST00000084867.7
Cmtm7

CKLF-like MARVEL transmembrane domain containing 7

chr7_+_16781341 7.725 ENSMUST00000108496.2
Slc1a5
solute carrier family 1 (neutral amino acid transporter), member 5
chr10_+_121033960 7.600 ENSMUST00000020439.4
ENSMUST00000175867.1
Wif1

Wnt inhibitory factor 1

chr9_-_100571049 7.575 ENSMUST00000093792.2
Slc35g2
solute carrier family 35, member G2
chr2_+_91256144 7.333 ENSMUST00000154959.1
ENSMUST00000059566.4
Pacsin3

protein kinase C and casein kinase substrate in neurons 3

chr9_+_72438519 7.331 ENSMUST00000184604.1
Mns1
meiosis-specific nuclear structural protein 1
chr1_-_119053619 7.252 ENSMUST00000062483.8
Gli2
GLI-Kruppel family member GLI2
chr9_+_15520830 7.164 ENSMUST00000178999.1
Smco4
single-pass membrane protein with coiled-coil domains 4
chr6_+_134929089 7.078 ENSMUST00000183867.1
ENSMUST00000184991.1
ENSMUST00000183905.1
RP23-45G16.5


RP23-45G16.5


chr7_+_127211608 7.044 ENSMUST00000032910.6
Mylpf
myosin light chain, phosphorylatable, fast skeletal muscle
chr11_+_120949053 6.992 ENSMUST00000154187.1
ENSMUST00000100130.3
ENSMUST00000129473.1
ENSMUST00000168579.1
Slc16a3



solute carrier family 16 (monocarboxylic acid transporters), member 3



chr1_-_138847579 6.941 ENSMUST00000093486.3
ENSMUST00000046870.6
Lhx9

LIM homeobox protein 9

chr11_+_43528759 6.836 ENSMUST00000050574.6
Ccnjl
cyclin J-like
chr3_+_27984145 6.774 ENSMUST00000067757.4
Pld1
phospholipase D1
chr2_-_91931675 6.622 ENSMUST00000111309.1
Mdk
midkine
chr19_-_10203880 6.577 ENSMUST00000142241.1
ENSMUST00000116542.2
ENSMUST00000025651.5
ENSMUST00000156291.1
Fen1



flap structure specific endonuclease 1



chr6_-_92943485 6.533 ENSMUST00000113438.1
Adamts9
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 9
chr17_-_15375969 6.474 ENSMUST00000014917.7
Dll1
delta-like 1 (Drosophila)
chr2_+_59612034 6.432 ENSMUST00000112568.1
ENSMUST00000037526.4
Tanc1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr6_-_72235559 6.418 ENSMUST00000042646.7
Atoh8
atonal homolog 8 (Drosophila)
chr10_-_92165159 6.404 ENSMUST00000182567.1
ENSMUST00000181604.2
ENSMUST00000181213.1
Rmst


rhabdomyosarcoma 2 associated transcript (non-coding RNA)


chr7_-_99353104 6.323 ENSMUST00000169437.1
ENSMUST00000094154.4
Serpinh1

serine (or cysteine) peptidase inhibitor, clade H, member 1

chr2_-_172370506 6.319 ENSMUST00000109139.1
ENSMUST00000028997.7
ENSMUST00000109140.3
Aurka


aurora kinase A


chr1_+_138963709 6.315 ENSMUST00000168527.1
Dennd1b
DENN/MADD domain containing 1B
chr2_-_91931696 6.263 ENSMUST00000090602.5
Mdk
midkine
chr2_+_91255954 6.261 ENSMUST00000134699.1
Pacsin3
protein kinase C and casein kinase substrate in neurons 3
chr10_+_128238034 6.140 ENSMUST00000105245.2
Timeless
timeless circadian clock 1
chr4_-_147936713 6.136 ENSMUST00000105712.1
ENSMUST00000019199.7
Plod1

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1

chr16_-_45844228 6.045 ENSMUST00000076333.5
Phldb2
pleckstrin homology-like domain, family B, member 2
chr12_-_69228167 6.035 ENSMUST00000021359.5
Pole2
polymerase (DNA directed), epsilon 2 (p59 subunit)
chr2_+_30845059 6.000 ENSMUST00000041659.5
Prrx2
paired related homeobox 2
chr12_-_10900296 5.886 ENSMUST00000085735.2
Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chr16_-_45844303 5.857 ENSMUST00000036355.6
Phldb2
pleckstrin homology-like domain, family B, member 2
chr4_-_41695442 5.822 ENSMUST00000102961.3
ENSMUST00000064443.6
Cntfr

ciliary neurotrophic factor receptor

chr17_-_70851710 5.778 ENSMUST00000166395.2
Tgif1
TGFB-induced factor homeobox 1
chr17_-_58991343 5.766 ENSMUST00000025064.7
2610034M16Rik
RIKEN cDNA 2610034M16 gene
chr2_+_71389239 5.735 ENSMUST00000028408.2
Hat1
histone aminotransferase 1
chr9_-_77544870 5.699 ENSMUST00000183873.1
Lrrc1
leucine rich repeat containing 1
chr10_-_23349887 5.667 ENSMUST00000074366.6
ENSMUST00000092665.4
Eya4

eyes absent 4 homolog (Drosophila)

chr11_-_115813621 5.649 ENSMUST00000041684.4
ENSMUST00000156812.1
Caskin2

CASK-interacting protein 2

chr7_-_118995211 5.584 ENSMUST00000008878.8
Gprc5b
G protein-coupled receptor, family C, group 5, member B
chr6_+_53573364 5.573 ENSMUST00000047450.7
Creb5
cAMP responsive element binding protein 5
chr7_-_25250720 5.518 ENSMUST00000116343.2
ENSMUST00000045847.8
Erf

Ets2 repressor factor

chr2_+_30061754 5.372 ENSMUST00000149578.1
ENSMUST00000102866.3
Set

SET nuclear oncogene

chr12_-_56536895 5.343 ENSMUST00000001536.8
Nkx2-1
NK2 homeobox 1
chr7_-_110061319 5.329 ENSMUST00000098110.2
AA474408
expressed sequence AA474408
chr2_-_28466266 5.321 ENSMUST00000127683.1
ENSMUST00000086370.4
1700007K13Rik

RIKEN cDNA 1700007K13 gene

chr5_-_100820929 5.315 ENSMUST00000117364.1
ENSMUST00000055245.6
Fam175a

family with sequence similarity 175, member A

chr9_-_97018823 5.296 ENSMUST00000055433.4
Spsb4
splA/ryanodine receptor domain and SOCS box containing 4
chr18_-_53418004 5.293 ENSMUST00000025419.7
Ppic
peptidylprolyl isomerase C
chr4_+_128883549 5.272 ENSMUST00000035667.8
Trim62
tripartite motif-containing 62
chr10_-_80421847 5.246 ENSMUST00000156244.1
Tcf3
transcription factor 3
chr7_-_19310035 5.134 ENSMUST00000003640.2
Fosb
FBJ osteosarcoma oncogene B
chr4_+_59626189 5.016 ENSMUST00000070150.4
ENSMUST00000052420.6
E130308A19Rik

RIKEN cDNA E130308A19 gene

chr5_-_137116177 4.982 ENSMUST00000054384.5
ENSMUST00000152207.1
Trim56

tripartite motif-containing 56

chr15_+_78926720 4.981 ENSMUST00000089377.5
Lgals1
lectin, galactose binding, soluble 1
chr19_+_25505618 4.888 ENSMUST00000025755.4
Dmrt1
doublesex and mab-3 related transcription factor 1
chr10_-_81349085 4.816 ENSMUST00000141171.1
Hmg20b
high mobility group 20B
chr3_-_127780461 4.700 ENSMUST00000029662.5
ENSMUST00000161239.1
Alpk1

alpha-kinase 1

chr5_+_30105161 4.690 ENSMUST00000058045.4
Gareml
GRB2 associated, regulator of MAPK1-like
chr5_-_116422858 4.681 ENSMUST00000036991.4
Hspb8
heat shock protein 8
chr4_-_107923519 4.634 ENSMUST00000106719.1
ENSMUST00000106720.2
ENSMUST00000131644.1
ENSMUST00000030345.8
Cpt2



carnitine palmitoyltransferase 2



chr13_-_3918157 4.614 ENSMUST00000091853.4
Net1
neuroepithelial cell transforming gene 1
chr2_+_35109482 4.492 ENSMUST00000028235.4
ENSMUST00000156933.1
ENSMUST00000028237.8
Cep110


centrosomal protein 110


chr7_+_112679314 4.484 ENSMUST00000084705.5
ENSMUST00000059768.10
Tead1

TEA domain family member 1

chr6_-_128438673 4.479 ENSMUST00000032508.4
Fkbp4
FK506 binding protein 4
chr5_-_129787175 4.460 ENSMUST00000031399.6
Psph
phosphoserine phosphatase
chr1_-_136234113 4.370 ENSMUST00000120339.1
ENSMUST00000048668.8
5730559C18Rik

RIKEN cDNA 5730559C18 gene

chr9_-_77544829 4.351 ENSMUST00000183734.1
Lrrc1
leucine rich repeat containing 1
chr4_+_62965560 4.328 ENSMUST00000030043.6
ENSMUST00000107415.1
ENSMUST00000064814.5
Zfp618


zinc finger protein 618


chr6_-_119467210 4.328 ENSMUST00000118120.1
Wnt5b
wingless-related MMTV integration site 5B
chr8_+_95633500 4.311 ENSMUST00000034094.9
Gins3
GINS complex subunit 3 (Psf3 homolog)
chr11_+_34314757 4.281 ENSMUST00000165963.1
ENSMUST00000093192.3
Fam196b

family with sequence similarity 196, member B

chr15_+_57694651 4.235 ENSMUST00000096430.4
Zhx2
zinc fingers and homeoboxes 2
chr17_-_25727364 4.157 ENSMUST00000170070.1
ENSMUST00000048054.7
Chtf18

CTF18, chromosome transmission fidelity factor 18

chr7_-_44815658 4.144 ENSMUST00000107893.1
Atf5
activating transcription factor 5
chr1_-_193273099 4.007 ENSMUST00000009777.2
G0s2
G0/G1 switch gene 2
chr7_-_140102384 3.918 ENSMUST00000120034.1
ENSMUST00000121115.1
ENSMUST00000026539.7
Fuom


fucose mutarotase


chr11_+_26387194 3.904 ENSMUST00000109509.1
ENSMUST00000136830.1
Fancl

Fanconi anemia, complementation group L

chr1_-_17097839 3.886 ENSMUST00000038382.4
Jph1
junctophilin 1
chr1_-_44101661 3.837 ENSMUST00000152239.1
Tex30
testis expressed 30
chr5_-_50058908 3.824 ENSMUST00000030971.5
Gpr125
G protein-coupled receptor 125
chr6_+_56832059 3.823 ENSMUST00000031795.7
Fkbp9
FK506 binding protein 9
chr9_+_65141154 3.788 ENSMUST00000034961.4
Igdcc3
immunoglobulin superfamily, DCC subclass, member 3
chr11_-_100939357 3.773 ENSMUST00000092671.5
ENSMUST00000103114.1
Stat3

signal transducer and activator of transcription 3

chr7_+_75610038 3.714 ENSMUST00000125771.1
Akap13
A kinase (PRKA) anchor protein 13
chr17_+_47593444 3.680 ENSMUST00000182209.1
Ccnd3
cyclin D3
chr5_-_5694024 3.631 ENSMUST00000115425.2
ENSMUST00000115427.1
ENSMUST00000115424.2
ENSMUST00000015797.4
Steap2



six transmembrane epithelial antigen of prostate 2



chr6_+_128438757 3.631 ENSMUST00000144745.1
Gm10069
predicted gene 10069
chr12_+_81026800 3.556 ENSMUST00000110347.2
ENSMUST00000021564.4
ENSMUST00000129362.1
Smoc1


SPARC related modular calcium binding 1


chr12_+_37880700 3.549 ENSMUST00000040500.7
Dgkb
diacylglycerol kinase, beta
chr5_+_32611171 3.539 ENSMUST00000072311.6
ENSMUST00000168707.2
Yes1

Yamaguchi sarcoma viral (v-yes) oncogene homolog 1

chr5_-_149636164 3.519 ENSMUST00000076410.4
Hsph1
heat shock 105kDa/110kDa protein 1
chr6_-_39206782 3.284 ENSMUST00000002305.8
Jhdm1d
jumonji C domain-containing histone demethylase 1 homolog D (S. cerevisiae)
chr15_-_8710734 3.274 ENSMUST00000005493.7
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr7_+_112679327 3.242 ENSMUST00000106638.2
Tead1
TEA domain family member 1
chr8_+_15011025 3.242 ENSMUST00000069399.6
Kbtbd11
kelch repeat and BTB (POZ) domain containing 11
chr5_-_149051604 3.235 ENSMUST00000093196.4
Hmgb1
high mobility group box 1
chr5_+_7179299 3.229 ENSMUST00000179460.1
Tubb4b-ps1
tubulin, beta 4B class IVB, pseudogene 1
chr6_-_21851914 3.208 ENSMUST00000134635.1
ENSMUST00000123116.1
ENSMUST00000120965.1
Tspan12


tetraspanin 12


chr4_+_141242850 3.171 ENSMUST00000138096.1
ENSMUST00000006618.2
ENSMUST00000125392.1
Arhgef19


Rho guanine nucleotide exchange factor (GEF) 19


chr14_+_28504736 3.163 ENSMUST00000063465.4
Wnt5a
wingless-related MMTV integration site 5A
chr2_+_31759932 3.155 ENSMUST00000028190.6
Abl1
c-abl oncogene 1, non-receptor tyrosine kinase
chr1_+_95313607 3.147 ENSMUST00000059975.6
Fam174a
family with sequence similarity 174, member A
chr5_+_139423151 3.140 ENSMUST00000066211.4
Gper1
G protein-coupled estrogen receptor 1
chr17_+_47593516 3.101 ENSMUST00000182874.1
Ccnd3
cyclin D3
chr6_-_21852509 3.063 ENSMUST00000031678.3
Tspan12
tetraspanin 12
chr5_-_120472763 3.063 ENSMUST00000052258.7
ENSMUST00000031594.6
Sdsl

serine dehydratase-like

chr7_+_83631959 3.058 ENSMUST00000075418.7
ENSMUST00000117410.1
Stard5

StAR-related lipid transfer (START) domain containing 5

chr4_+_48540067 3.024 ENSMUST00000064807.2
Msantd3
Myb/SANT-like DNA-binding domain containing 3
chr3_+_127789872 2.995 ENSMUST00000054483.7
ENSMUST00000163775.1
Tifa

TRAF-interacting protein with forkhead-associated domain

chr9_-_72111172 2.960 ENSMUST00000183992.1
Tcf12
transcription factor 12
chr7_+_25681158 2.918 ENSMUST00000108403.3
B9d2
B9 protein domain 2
chr17_-_34627148 2.891 ENSMUST00000171376.1
ENSMUST00000169287.1
Ppt2

palmitoyl-protein thioesterase 2

chr5_-_124354671 2.874 ENSMUST00000031341.4
Cdk2ap1
CDK2 (cyclin-dependent kinase 2)-associated protein 1
chr6_-_76497631 2.832 ENSMUST00000097218.5
Gm9008
predicted pseudogene 9008
chr3_+_86224665 2.815 ENSMUST00000107635.1
Lrba
LPS-responsive beige-like anchor
chrX_+_56779699 2.777 ENSMUST00000114772.2
ENSMUST00000114768.3
ENSMUST00000155882.1
Fhl1


four and a half LIM domains 1


chr14_+_79481164 2.736 ENSMUST00000040131.5
Elf1
E74-like factor 1
chr2_-_151039363 2.732 ENSMUST00000066640.4
ENSMUST00000128627.1
Nanp
Ninl
N-acetylneuraminic acid phosphatase
ninein-like
chr17_+_36958571 2.710 ENSMUST00000040177.6
Znrd1as
Znrd1 antisense
chr3_+_96161981 2.702 ENSMUST00000054356.9
Mtmr11
myotubularin related protein 11
chr4_+_48539909 2.699 ENSMUST00000061135.1
Msantd3
Myb/SANT-like DNA-binding domain containing 3
chr18_+_60925644 2.695 ENSMUST00000115297.1
Camk2a
calcium/calmodulin-dependent protein kinase II alpha
chr11_+_115564434 2.680 ENSMUST00000021085.4
Nup85
nucleoporin 85
chr2_+_29889785 2.676 ENSMUST00000113763.1
ENSMUST00000113757.1
ENSMUST00000113756.1
ENSMUST00000133233.1
ENSMUST00000113759.2
ENSMUST00000113755.1
ENSMUST00000137558.1
ENSMUST00000046571.7
Odf2







outer dense fiber of sperm tails 2







chr2_+_120463566 2.670 ENSMUST00000028749.7
ENSMUST00000110721.1
Capn3

calpain 3

chr1_+_131867224 2.665 ENSMUST00000112386.1
ENSMUST00000027693.7
Rab7l1

RAB7, member RAS oncogene family-like 1

chr1_-_79858627 2.652 ENSMUST00000027467.4
Serpine2
serine (or cysteine) peptidase inhibitor, clade E, member 2
chr3_+_68869563 2.650 ENSMUST00000054551.2
1110032F04Rik
RIKEN cDNA 1110032F04 gene
chr4_-_43030440 2.639 ENSMUST00000135660.1
Stoml2
stomatin (Epb7.2)-like 2
chrX_-_157568983 2.631 ENSMUST00000065806.4
Yy2
Yy2 transcription factor
chr7_-_141443314 2.618 ENSMUST00000106005.2
Lrdd
leucine-rich and death domain containing
chr9_+_66126611 2.615 ENSMUST00000034945.5
Fam96a
family with sequence similarity 96, member A
chr1_-_45503282 2.607 ENSMUST00000086430.4
Col5a2
collagen, type V, alpha 2
chr8_-_80739497 2.557 ENSMUST00000043359.8
Smarca5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr1_+_104768510 2.551 ENSMUST00000062528.8
Cdh20
cadherin 20
chr8_+_70863127 2.545 ENSMUST00000050921.2
A230052G05Rik
RIKEN cDNA A230052G05 gene
chr7_+_127471484 2.535 ENSMUST00000033095.8
Prr14
proline rich 14
chr2_+_31759993 2.534 ENSMUST00000124089.1
Abl1
c-abl oncogene 1, non-receptor tyrosine kinase
chr4_-_154097105 2.527 ENSMUST00000105643.1
ENSMUST00000133533.1
ENSMUST00000097762.4
Trp73


transformation related protein 73


chr10_+_128092771 2.490 ENSMUST00000170054.2
ENSMUST00000045621.8
Baz2a

bromodomain adjacent to zinc finger domain, 2A

chr4_-_11254248 2.458 ENSMUST00000044616.3
ENSMUST00000108319.2
ENSMUST00000108318.2
Ints8


integrator complex subunit 8


chr18_-_24020307 2.448 ENSMUST00000153337.1
ENSMUST00000148525.1
Zfp191

zinc finger protein 191

chr1_+_187215501 2.436 ENSMUST00000097443.3
ENSMUST00000065573.7
ENSMUST00000110943.2
ENSMUST00000044812.5
Gpatch2



G patch domain containing 2



chr10_-_127070254 2.411 ENSMUST00000060991.4
Tspan31
tetraspanin 31
chr2_-_26246707 2.407 ENSMUST00000166349.1
C030048H21Rik
RIKEN cDNA C030048H21 gene
chr4_+_150236685 2.392 ENSMUST00000150175.1
Eno1
enolase 1, alpha non-neuron
chr6_-_142507805 2.383 ENSMUST00000134191.1
ENSMUST00000032373.5
Ldhb

lactate dehydrogenase B

chr19_+_53903351 2.377 ENSMUST00000025931.6
ENSMUST00000165617.1
Pdcd4

programmed cell death 4

chr6_+_66896397 2.371 ENSMUST00000043148.6
ENSMUST00000114228.1
ENSMUST00000114227.1
ENSMUST00000114226.1
ENSMUST00000114225.1
ENSMUST00000114224.1
Gng12





guanine nucleotide binding protein (G protein), gamma 12





chr1_+_178798438 2.363 ENSMUST00000160789.1
Kif26b
kinesin family member 26B
chr14_-_101609033 2.362 ENSMUST00000161991.1
ENSMUST00000100340.3
Tbc1d4

TBC1 domain family, member 4

chr2_+_158624882 2.361 ENSMUST00000045644.8
Actr5
ARP5 actin-related protein 5
chr10_+_80826656 2.355 ENSMUST00000060987.8
ENSMUST00000177850.1
ENSMUST00000180036.1
ENSMUST00000179172.1
Oaz1



ornithine decarboxylase antizyme 1



chr7_-_120982260 2.344 ENSMUST00000033169.8
Cdr2
cerebellar degeneration-related 2
chr19_+_5366764 2.343 ENSMUST00000025759.7
Eif1ad
eukaryotic translation initiation factor 1A domain containing
chr18_-_47368446 2.311 ENSMUST00000076043.6
ENSMUST00000135790.1
Sema6a

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A

chr16_+_77014069 2.296 ENSMUST00000023580.6
Usp25
ubiquitin specific peptidase 25
chr5_+_140735526 2.294 ENSMUST00000120630.2
Amz1
archaelysin family metallopeptidase 1
chr18_-_61259987 2.292 ENSMUST00000170335.2
Rps2-ps10
ribosomal protein S2, pseudogene 10
chr1_-_121567906 2.290 ENSMUST00000001724.5
Ddx18
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr1_-_55088024 2.286 ENSMUST00000027123.8
Hspd1
heat shock protein 1 (chaperonin)
chr1_+_186749368 2.268 ENSMUST00000180869.1
A430105J06Rik
RIKEN cDNA A430105J06 gene
chr7_-_127286385 2.267 ENSMUST00000172206.2
Gm17511
predicted gene, 17511
chr6_+_134035691 2.261 ENSMUST00000081028.6
ENSMUST00000111963.1
Etv6

ets variant gene 6 (TEL oncogene)

chr17_-_34627365 2.259 ENSMUST00000064953.8
ENSMUST00000170345.1
ENSMUST00000171121.2
ENSMUST00000168391.2
ENSMUST00000169067.2
Ppt2




palmitoyl-protein thioesterase 2





Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.9 29.5 GO:2000981 negative regulation of mechanoreceptor differentiation(GO:0045632) negative regulation of inner ear receptor cell differentiation(GO:2000981)
4.3 12.9 GO:0030421 defecation(GO:0030421)
3.4 10.2 GO:0021698 cerebellar cortex structural organization(GO:0021698)
2.9 11.5 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
2.5 12.6 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
2.3 11.3 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
2.2 8.7 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
2.1 8.3 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
2.1 32.9 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
2.0 6.1 GO:1904975 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
1.9 7.7 GO:0002337 B-1a B cell differentiation(GO:0002337)
1.9 5.7 GO:1900275 B cell proliferation involved in immune response(GO:0002322) negative regulation of phospholipase C activity(GO:1900275)
1.8 7.3 GO:0060032 notochord regression(GO:0060032)
1.8 5.3 GO:0021759 globus pallidus development(GO:0021759)
1.7 6.9 GO:0035262 gonad morphogenesis(GO:0035262)
1.7 11.9 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
1.7 6.8 GO:0015825 L-serine transport(GO:0015825)
1.6 8.1 GO:0034421 post-translational protein acetylation(GO:0034421)
1.6 6.3 GO:0007056 spindle assembly involved in female meiosis(GO:0007056) positive regulation of oocyte development(GO:0060282)
1.5 6.1 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
1.5 5.8 GO:0003360 brainstem development(GO:0003360)
1.4 12.8 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
1.3 9.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
1.2 4.8 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345) positive regulation of NK T cell activation(GO:0051135)
1.2 18.1 GO:0021891 olfactory bulb interneuron development(GO:0021891)
1.2 3.6 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
1.1 5.5 GO:0010668 ectodermal cell differentiation(GO:0010668)
1.1 6.6 GO:0043137 DNA replication, removal of RNA primer(GO:0043137) positive regulation of sister chromatid cohesion(GO:0045876)
1.1 3.2 GO:0045819 plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819)
1.0 6.8 GO:0032534 regulation of microvillus assembly(GO:0032534)
1.0 7.6 GO:0014807 regulation of somitogenesis(GO:0014807)
0.9 3.8 GO:1902724 positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.9 5.6 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.9 5.5 GO:1905063 regulation of vascular smooth muscle cell differentiation(GO:1905063)
0.9 4.5 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.9 2.7 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.9 2.6 GO:1990046 positive regulation of mitochondrial DNA replication(GO:0090297) regulation of cardiolipin metabolic process(GO:1900208) positive regulation of cardiolipin metabolic process(GO:1900210) stress-induced mitochondrial fusion(GO:1990046)
0.9 5.2 GO:0002326 B cell lineage commitment(GO:0002326)
0.9 2.6 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.9 7.8 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.9 7.7 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.8 5.9 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.8 5.0 GO:0002317 plasma cell differentiation(GO:0002317) positive regulation of viral entry into host cell(GO:0046598)
0.8 3.3 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.8 4.9 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.8 2.4 GO:0072092 ureteric bud invasion(GO:0072092)
0.8 4.6 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.7 9.5 GO:0046643 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.7 3.6 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.7 6.5 GO:1902913 positive regulation of melanocyte differentiation(GO:0045636) positive regulation of neuroepithelial cell differentiation(GO:1902913)
0.7 7.9 GO:0032048 cardiolipin metabolic process(GO:0032048)
0.7 5.7 GO:0016576 histone dephosphorylation(GO:0016576)
0.7 7.0 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.7 2.0 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.7 4.0 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.7 2.7 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.6 5.7 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.6 2.5 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.6 1.9 GO:0002842 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) positive regulation of T cell mediated immune response to tumor cell(GO:0002842) protein import into mitochondrial intermembrane space(GO:0045041)
0.6 3.7 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.6 1.9 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.6 13.6 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.6 1.2 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.6 2.4 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.6 1.7 GO:1902071 positive regulation of cellular response to hypoxia(GO:1900039) regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.6 1.1 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.6 7.3 GO:0070986 left/right axis specification(GO:0070986)
0.5 2.2 GO:0006203 dGTP catabolic process(GO:0006203) dATP catabolic process(GO:0046061)
0.5 4.2 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.5 8.7 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.5 1.5 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.5 3.9 GO:0006004 fucose metabolic process(GO:0006004)
0.5 1.5 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.5 3.4 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.5 10.3 GO:0046596 regulation of viral entry into host cell(GO:0046596)
0.5 2.4 GO:0019244 lactate biosynthetic process from pyruvate(GO:0019244)
0.5 1.4 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.5 1.8 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.5 1.4 GO:2000564 CD8-positive, alpha-beta T cell proliferation(GO:0035740) negative regulation of regulatory T cell differentiation(GO:0045590) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.4 12.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.4 5.4 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.4 5.3 GO:0030238 male sex determination(GO:0030238)
0.4 6.4 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.4 1.2 GO:1903054 protein targeting to vacuole involved in autophagy(GO:0071211) lysosomal membrane organization(GO:0097212) negative regulation of extracellular matrix organization(GO:1903054) positive regulation of protein folding(GO:1903334)
0.4 2.0 GO:1904659 glucose transmembrane transport(GO:1904659)
0.4 4.8 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.4 1.8 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.4 1.8 GO:0003420 regulation of growth plate cartilage chondrocyte proliferation(GO:0003420)
0.4 0.7 GO:0060686 prostatic bud formation(GO:0060513) regulation of prostatic bud formation(GO:0060685) negative regulation of prostatic bud formation(GO:0060686)
0.4 1.8 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
0.4 2.1 GO:0046349 amino sugar biosynthetic process(GO:0046349)
0.4 0.7 GO:0002489 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489)
0.3 7.6 GO:0045793 positive regulation of cell size(GO:0045793)
0.3 1.0 GO:0002946 tRNA C5-cytosine methylation(GO:0002946)
0.3 1.7 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.3 10.8 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.3 11.8 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.3 4.2 GO:0051451 myoblast migration(GO:0051451)
0.3 3.5 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.3 0.9 GO:0033566 gamma-tubulin complex localization(GO:0033566)
0.3 1.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.3 3.1 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.3 1.9 GO:0007296 vitellogenesis(GO:0007296)
0.3 2.6 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.3 2.4 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.3 12.3 GO:0032611 interleukin-1 beta production(GO:0032611)
0.3 0.5 GO:0072076 nephrogenic mesenchyme development(GO:0072076)
0.2 0.7 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.2 1.7 GO:0098535 de novo centriole assembly(GO:0098535)
0.2 11.9 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.2 3.5 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
0.2 6.4 GO:0007520 myoblast fusion(GO:0007520)
0.2 6.3 GO:0010842 retina layer formation(GO:0010842)
0.2 0.9 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.2 2.7 GO:0099628 angiotensin-activated signaling pathway(GO:0038166) receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.2 3.9 GO:0042474 middle ear morphogenesis(GO:0042474)
0.2 1.4 GO:0042572 retinol metabolic process(GO:0042572)
0.2 1.8 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.2 0.9 GO:0032472 Golgi calcium ion transport(GO:0032472)
0.2 0.7 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.2 2.4 GO:0070914 UV-damage excision repair(GO:0070914)
0.2 0.5 GO:1904154 protein localization to endoplasmic reticulum exit site(GO:0070973) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.2 1.6 GO:0042989 sequestering of actin monomers(GO:0042989)
0.2 1.9 GO:0002227 innate immune response in mucosa(GO:0002227)
0.2 2.7 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.2 2.9 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.2 1.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.2 0.3 GO:0019433 triglyceride catabolic process(GO:0019433)
0.2 1.5 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.1 10.0 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.1 4.9 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) negative regulation of cell cycle G2/M phase transition(GO:1902750)
0.1 5.6 GO:0060612 adipose tissue development(GO:0060612)
0.1 0.6 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 0.7 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.1 7.9 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.1 3.3 GO:0006801 superoxide metabolic process(GO:0006801)
0.1 0.5 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.1 1.8 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.5 GO:0007113 endomitotic cell cycle(GO:0007113)
0.1 1.9 GO:0098869 cellular oxidant detoxification(GO:0098869)
0.1 2.0 GO:0050687 negative regulation of defense response to virus(GO:0050687)
0.1 0.9 GO:0040016 embryonic cleavage(GO:0040016)
0.1 1.9 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1 1.6 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.1 0.7 GO:0044241 lipid digestion(GO:0044241)
0.1 0.7 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 0.2 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.1 1.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 2.5 GO:0016180 snRNA processing(GO:0016180)
0.1 0.8 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.1 0.3 GO:0015793 renal water transport(GO:0003097) glycerol transport(GO:0015793) renal water absorption(GO:0070295)
0.1 0.7 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 0.9 GO:0000132 establishment of mitotic spindle orientation(GO:0000132) establishment of mitotic spindle localization(GO:0040001)
0.1 1.9 GO:0045116 protein neddylation(GO:0045116)
0.1 1.2 GO:0048311 mitochondrion distribution(GO:0048311)
0.1 1.3 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.1 1.2 GO:0030813 positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.1 2.4 GO:0051099 positive regulation of binding(GO:0051099)
0.1 5.3 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.1 0.4 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.8 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 1.3 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.1 0.4 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.1 1.7 GO:0048246 macrophage chemotaxis(GO:0048246)
0.1 1.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.5 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 1.6 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.1 3.8 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.1 3.6 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.1 0.9 GO:0019369 drug metabolic process(GO:0017144) arachidonic acid metabolic process(GO:0019369)
0.1 0.7 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 1.0 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 1.4 GO:0033622 integrin activation(GO:0033622)
0.1 0.2 GO:0071285 cellular response to lithium ion(GO:0071285)
0.1 2.3 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.1 0.2 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.1 0.6 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 0.7 GO:0042182 ketone catabolic process(GO:0042182)
0.1 0.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 1.0 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 1.2 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.4 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0 1.6 GO:0048636 positive regulation of striated muscle tissue development(GO:0045844) positive regulation of muscle organ development(GO:0048636) positive regulation of muscle tissue development(GO:1901863)
0.0 2.3 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.1 GO:0001803 antibody-dependent cellular cytotoxicity(GO:0001788) type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.0 2.0 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.8 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.6 GO:0046621 negative regulation of organ growth(GO:0046621)
0.0 3.8 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 0.2 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.0 5.3 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 0.1 GO:0034242 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.0 0.3 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 1.3 GO:0019915 lipid storage(GO:0019915)
0.0 1.1 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 1.0 GO:1901796 regulation of signal transduction by p53 class mediator(GO:1901796)
0.0 0.5 GO:0031018 endocrine pancreas development(GO:0031018)
0.0 2.4 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.4 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.8 GO:0000154 rRNA modification(GO:0000154)
0.0 0.6 GO:0006414 translational elongation(GO:0006414)
0.0 0.2 GO:0031274 regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 2.0 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.2 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 1.0 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.4 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 1.7 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.0 0.2 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.6 GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway(GO:0007178)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 1.5 GO:0007601 visual perception(GO:0007601)
0.0 0.5 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.0 1.2 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.1 GO:0090472 dibasic protein processing(GO:0090472)
0.0 0.0 GO:1904468 negative regulation of tumor necrosis factor secretion(GO:1904468)
0.0 0.1 GO:0030913 paranodal junction assembly(GO:0030913)
0.0 0.1 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.4 GO:0031641 regulation of myelination(GO:0031641)
0.0 0.9 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 9.1 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
2.1 6.3 GO:0042585 germinal vesicle(GO:0042585)
2.1 16.7 GO:0005818 aster(GO:0005818)
1.9 5.8 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
1.9 7.7 GO:0071148 TEAD-1-YAP complex(GO:0071148)
1.6 8.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
1.6 11.5 GO:0097550 transcriptional preinitiation complex(GO:0097550)
1.3 7.8 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
1.2 6.0 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
1.2 4.8 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.9 2.7 GO:0099573 glutamatergic postsynaptic density(GO:0099573)
0.9 2.6 GO:0005588 collagen type V trimer(GO:0005588)
0.8 12.6 GO:0030061 mitochondrial crista(GO:0030061)
0.8 3.9 GO:0030314 junctional membrane complex(GO:0030314)
0.7 11.2 GO:0045180 basal cortex(GO:0045180)
0.7 3.6 GO:0031523 Myb complex(GO:0031523)
0.7 8.0 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.6 1.2 GO:0099524 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.5 2.5 GO:0033553 rDNA heterochromatin(GO:0033553)
0.5 1.5 GO:0030905 retromer, tubulation complex(GO:0030905)
0.5 9.9 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.5 4.2 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.4 2.6 GO:0005677 chromatin silencing complex(GO:0005677)
0.4 23.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.4 3.9 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.3 2.7 GO:0045171 intercellular bridge(GO:0045171)
0.3 10.2 GO:0051233 spindle midzone(GO:0051233)
0.3 4.8 GO:0097539 ciliary transition fiber(GO:0097539)
0.3 3.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.3 2.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.3 1.5 GO:0032389 MutLalpha complex(GO:0032389)
0.3 1.7 GO:0098536 deuterosome(GO:0098536)
0.3 17.4 GO:0016459 myosin complex(GO:0016459)
0.3 2.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.3 2.7 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.3 2.6 GO:0031595 nuclear proteasome complex(GO:0031595)
0.3 3.1 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.3 18.9 GO:0016328 lateral plasma membrane(GO:0016328)
0.2 1.4 GO:0097512 cardiac myofibril(GO:0097512)
0.2 1.9 GO:0061700 GATOR2 complex(GO:0061700)
0.2 2.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.2 2.9 GO:0036038 MKS complex(GO:0036038)
0.2 2.6 GO:0042101 T cell receptor complex(GO:0042101)
0.2 1.9 GO:0032420 stereocilium(GO:0032420)
0.2 0.7 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.2 5.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 2.5 GO:0032039 integrator complex(GO:0032039)
0.2 2.1 GO:0005614 interstitial matrix(GO:0005614)
0.1 8.3 GO:0005882 intermediate filament(GO:0005882)
0.1 1.1 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 14.2 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.1 0.4 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 2.0 GO:0031011 Ino80 complex(GO:0031011)
0.1 2.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 0.8 GO:0071203 WASH complex(GO:0071203)
0.1 1.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 1.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 1.0 GO:0000243 commitment complex(GO:0000243)
0.1 0.5 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 1.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 6.5 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 7.1 GO:0005811 lipid particle(GO:0005811)
0.1 5.8 GO:0031985 Golgi cisterna(GO:0031985)
0.1 1.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 1.5 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 2.3 GO:0031526 brush border membrane(GO:0031526)
0.1 1.1 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.1 3.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 3.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 6.3 GO:0005604 basement membrane(GO:0005604)
0.1 1.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 1.6 GO:0001741 XY body(GO:0001741)
0.1 1.6 GO:0030175 filopodium(GO:0030175)
0.1 1.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 3.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 4.6 GO:0030315 T-tubule(GO:0030315)
0.1 0.9 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 10.5 GO:0005802 trans-Golgi network(GO:0005802)
0.1 2.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.5 GO:0000974 Prp19 complex(GO:0000974)
0.1 0.9 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 1.5 GO:0005770 late endosome(GO:0005770)
0.0 6.6 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.1 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 5.1 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 2.1 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.6 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 3.5 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 2.4 GO:0005871 kinesin complex(GO:0005871)
0.0 1.0 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 12.8 GO:0016607 nuclear speck(GO:0016607)
0.0 8.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 5.3 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.9 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.2 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.6 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 5.3 GO:0016324 apical plasma membrane(GO:0016324)
0.0 2.3 GO:0000502 proteasome complex(GO:0000502)
0.0 3.9 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 9.5 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.8 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 4.0 GO:0031965 nuclear membrane(GO:0031965)
0.0 1.2 GO:0016605 PML body(GO:0016605)
0.0 1.0 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.6 GO:0005814 centriole(GO:0005814)
0.0 58.3 GO:0005634 nucleus(GO:0005634)
0.0 6.5 GO:0005739 mitochondrion(GO:0005739)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 11.5 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
3.1 12.5 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
2.6 7.8 GO:0004774 succinate-CoA ligase activity(GO:0004774)
1.9 16.7 GO:0061676 importin-alpha family protein binding(GO:0061676)
1.5 6.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
1.5 32.9 GO:0070410 co-SMAD binding(GO:0070410)
1.5 4.5 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
1.4 8.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
1.3 5.3 GO:0045131 pre-mRNA branch point binding(GO:0045131)
1.3 6.6 GO:0017108 5'-flap endonuclease activity(GO:0017108)
1.3 6.3 GO:0035174 histone serine kinase activity(GO:0035174)
1.2 3.6 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
1.1 9.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
1.1 3.2 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
1.1 3.2 GO:0005110 frizzled-2 binding(GO:0005110)
1.0 3.1 GO:0030284 estrogen receptor activity(GO:0030284)
1.0 13.6 GO:0019855 calcium channel inhibitor activity(GO:0019855)
1.0 3.1 GO:0032052 bile acid binding(GO:0032052)
1.0 7.0 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
1.0 5.0 GO:0005534 galactose binding(GO:0005534)
1.0 3.9 GO:0042806 fucose binding(GO:0042806)
1.0 5.8 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.9 4.6 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.9 3.6 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.9 4.5 GO:0032767 copper-dependent protein binding(GO:0032767)
0.9 5.2 GO:0070644 vitamin D response element binding(GO:0070644)
0.8 6.8 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.8 3.3 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.8 3.1 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.7 7.6 GO:0017147 Wnt-protein binding(GO:0017147)
0.7 2.0 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.7 2.7 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.7 2.7 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.6 6.5 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.6 1.9 GO:0005118 sevenless binding(GO:0005118)
0.6 2.4 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.6 2.4 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.6 8.2 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.6 1.7 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.5 3.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.5 4.8 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.5 3.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.5 1.5 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.5 9.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.5 1.9 GO:2001069 glycogen binding(GO:2001069)
0.5 5.7 GO:0070097 delta-catenin binding(GO:0070097)
0.4 5.3 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.4 3.0 GO:0016018 cyclosporin A binding(GO:0016018)
0.4 7.7 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.4 1.2 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.4 13.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.4 4.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.4 2.6 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.4 2.6 GO:1901612 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.4 3.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.4 5.9 GO:0030957 Tat protein binding(GO:0030957)
0.4 1.5 GO:1990460 leptin receptor binding(GO:1990460)
0.4 3.6 GO:0042301 phosphate ion binding(GO:0042301)
0.4 2.2 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.3 3.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.3 2.7 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.3 5.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.3 5.7 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.3 10.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.3 6.3 GO:0000400 four-way junction DNA binding(GO:0000400)
0.3 16.5 GO:0001784 phosphotyrosine binding(GO:0001784)
0.3 8.5 GO:0071837 HMG box domain binding(GO:0071837)
0.3 0.9 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.3 0.3 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.3 1.7 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.3 2.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.3 1.6 GO:0042731 PH domain binding(GO:0042731)
0.3 1.8 GO:0031419 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723) cobalamin binding(GO:0031419)
0.2 3.7 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.2 1.2 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.2 9.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.2 0.7 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.2 11.0 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.2 1.8 GO:0001972 retinoic acid binding(GO:0001972)
0.2 2.5 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.2 1.1 GO:0043532 angiostatin binding(GO:0043532)
0.2 2.7 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.2 1.8 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.2 1.5 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.2 1.6 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.2 1.4 GO:0043237 laminin-1 binding(GO:0043237)
0.2 1.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 1.8 GO:0001055 RNA polymerase II activity(GO:0001055)
0.2 6.4 GO:0005112 Notch binding(GO:0005112)
0.2 2.5 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.2 1.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.2 0.7 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.2 3.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 1.2 GO:0034452 dynactin binding(GO:0034452)
0.2 0.5 GO:0052740 phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.2 7.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 1.0 GO:0070728 leucine binding(GO:0070728)
0.2 6.4 GO:0070888 E-box binding(GO:0070888)
0.2 1.3 GO:0046790 virion binding(GO:0046790)
0.2 2.5 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 4.3 GO:0005109 frizzled binding(GO:0005109)
0.1 4.0 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 6.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.7 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 1.8 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 2.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.7 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 2.0 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.1 3.4 GO:0051018 protein kinase A binding(GO:0051018)
0.1 1.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 37.1 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 1.2 GO:0008430 selenium binding(GO:0008430)
0.1 0.5 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.1 1.6 GO:0016805 dipeptidase activity(GO:0016805)
0.1 2.0 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 1.0 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.1 1.8 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.1 10.2 GO:0003774 motor activity(GO:0003774)
0.1 3.6 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 14.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 1.7 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 2.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 5.2 GO:0005125 cytokine activity(GO:0005125)
0.1 7.5 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987)
0.1 2.1 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.5 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 1.9 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.1 0.8 GO:0019215 intermediate filament binding(GO:0019215)
0.1 1.1 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.3 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.4 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 4.3 GO:0019955 cytokine binding(GO:0019955)
0.1 0.4 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.2 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 0.4 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 6.6 GO:0008083 growth factor activity(GO:0008083)
0.1 0.8 GO:0031386 protein tag(GO:0031386)
0.1 1.6 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.0 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 1.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 1.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 1.3 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 3.5 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.1 0.5 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 1.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.5 GO:0031996 thioesterase binding(GO:0031996)
0.0 1.6 GO:0032452 histone demethylase activity(GO:0032452)
0.0 1.1 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 0.7 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 1.0 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.7 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.4 GO:0032554 purine deoxyribonucleotide binding(GO:0032554)
0.0 0.4 GO:0000182 rDNA binding(GO:0000182)
0.0 1.8 GO:0031491 nucleosome binding(GO:0031491)
0.0 1.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.5 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.7 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 5.2 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 2.2 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 1.4 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 1.0 GO:0017069 snRNA binding(GO:0017069)
0.0 0.1 GO:0019770 IgG receptor activity(GO:0019770)
0.0 2.3 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.3 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 3.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.6 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.7 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.2 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 0.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.7 GO:0008237 metallopeptidase activity(GO:0008237)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 3.2 GO:0005198 structural molecule activity(GO:0005198)
0.0 3.0 GO:0045296 cadherin binding(GO:0045296)
0.0 0.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.3 GO:0005310 dicarboxylic acid transmembrane transporter activity(GO:0005310)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 24.0 PID_AURORA_A_PATHWAY Aurora A signaling
0.5 48.3 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.4 13.4 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.4 22.3 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.4 13.0 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.3 7.3 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.3 12.0 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.3 14.9 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.3 6.1 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.3 5.6 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.3 3.8 ST_STAT3_PATHWAY STAT3 Pathway
0.3 11.0 PID_ATM_PATHWAY ATM pathway
0.3 7.9 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.3 6.8 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.2 4.1 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.2 6.2 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.2 6.7 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.2 8.9 PID_BMP_PATHWAY BMP receptor signaling
0.2 3.9 PID_BARD1_PATHWAY BARD1 signaling events
0.2 5.2 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.2 8.1 PID_PLK1_PATHWAY PLK1 signaling events
0.1 5.3 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 18.5 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 2.4 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.1 7.2 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.1 2.7 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 7.0 PID_CDC42_PATHWAY CDC42 signaling events
0.1 4.3 NABA_COLLAGENS Genes encoding collagen proteins
0.1 13.1 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 5.0 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.1 0.5 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.1 2.3 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 1.4 PID_IFNG_PATHWAY IFN-gamma pathway
0.1 3.5 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 3.4 PID_ERBB1_DOWNSTREAM_PATHWAY ErbB1 downstream signaling
0.0 0.3 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.4 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.8 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.5 PID_A6B1_A6B4_INTEGRIN_PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.9 WNT_SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.5 ST_FAS_SIGNALING_PATHWAY Fas Signaling Pathway
0.0 0.6 PID_ARF6_PATHWAY Arf6 signaling events
0.0 0.7 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 0.3 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.6 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.1 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.7 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 33.2 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.9 6.0 REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.8 7.0 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.7 6.6 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.6 12.8 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.6 6.7 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.6 18.9 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.6 9.1 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.5 3.7 REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.4 8.7 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.4 14.1 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.4 7.8 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.4 3.9 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.3 11.5 REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 Genes involved in Nuclear signaling by ERBB4
0.3 0.9 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.3 6.2 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.3 3.2 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.3 11.0 REACTOME_G1_PHASE Genes involved in G1 Phase
0.3 7.7 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2 15.3 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.2 1.8 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.2 13.3 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.2 3.6 REACTOME_PECAM1_INTERACTIONS Genes involved in PECAM1 interactions
0.2 3.1 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.2 3.9 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.2 1.3 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.2 1.8 REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.2 5.2 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.2 2.0 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 6.1 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 2.4 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism
0.1 9.0 REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1 0.7 REACTOME_P53_DEPENDENT_G1_DNA_DAMAGE_RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.1 3.6 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 1.8 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 0.5 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 4.0 REACTOME_INTERFERON_GAMMA_SIGNALING Genes involved in Interferon gamma signaling
0.1 1.5 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 2.1 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 0.9 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 5.0 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 2.3 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.1 0.5 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 3.7 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.1 2.1 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 5.6 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 4.0 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 2.2 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.1 1.6 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 2.4 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 1.0 REACTOME_DESTABILIZATION_OF_MRNA_BY_TRISTETRAPROLIN_TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 2.5 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 3.0 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 6.2 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 3.9 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.0 2.5 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.4 REACTOME_SIGNALING_BY_PDGF Genes involved in Signaling by PDGF
0.0 1.5 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.0 0.5 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 1.2 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.5 REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS Genes involved in G alpha (z) signalling events
0.0 0.5 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins